locus-tag	class	description
CK627_00010	COG0561	phosphatase activity
CK627_00025	COG1522	sequence-specific DNA binding
CK627_00040	COG1846	Transcriptional regulator
CK627_00045	COG2130	NADP-dependent
CK627_00050	COG1051	belongs to the nudix hydrolase family
CK627_00070	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
CK627_00075	COG1640	4-alpha-glucanotransferase
CK627_00080	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
CK627_00085	COG0676	glucose-6-phosphate 1-epimerase activity
CK627_00090	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
CK627_00095	COG0840	transmembrane signaling receptor activity
CK627_00170	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
CK627_00175	COG2885	chlorophyll binding
CK627_00180	COG0823	Involved in the tonB-independent uptake of proteins
CK627_00195	COG0811	peptide transport
CK627_00200	COG0824	Thioesterase
CK627_00205	COG3790	cyd operon protein YbgE
CK627_00210	COG4890	Cyd operon protein YbgT
CK627_00215	COG1294	oxidase, subunit
CK627_00220	COG1271	oxidase subunit
CK627_00225	COG2255	four-way junction helicase activity
CK627_00230	COG0632	four-way junction helicase activity
CK627_00235	COG0840	transmembrane signaling receptor activity
CK627_00240	COG0442	prolyl-tRNA aminoacylation
CK627_00245	COG4221	oxidoreductase activity
CK627_00260	COG1024	Enoyl-CoA hydratase
CK627_00270	COG0110	maltose O-acetyltransferase activity
CK627_00280	COG4166	transmembrane transport
CK627_00295	COG1872	DUF167
CK627_00300	COG0762	integral membrane protein
CK627_00305	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
CK627_00310	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
CK627_00320	COG2805	Type II/IV secretion system protein
CK627_00325	COG3022	response to hydroperoxide
CK627_00330	COG0513	Belongs to the DEAD box helicase family
CK627_00335	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
CK627_00360	COG0735	belongs to the Fur family
CK627_00365	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CK627_00380	COG0776	regulation of translation
CK627_00410	COG0560	Phosphoserine phosphatase
CK627_00420	COG3447	MASE1 domain protein
CK627_00420	COG5001	Diguanylate cyclase
CK627_00420	COG5002	protein histidine kinase activity
CK627_00425	COG0813	purine-nucleoside phosphorylase activity
CK627_00430	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
CK627_00435	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
CK627_00440	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
CK627_00450	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
CK627_00455	COG0084	hydrolase, TatD family'
CK627_00475	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
CK627_00480	COG0004	ammonium transporteR
CK627_00485	COG4974	Belongs to the 'phage' integrase family
CK627_00495	COG2932	Transcriptional regulator
CK627_00585	COG4695	Portal protein
CK627_00710	COG0795	lipopolysaccharide-transporting ATPase activity
CK627_00715	COG0795	lipopolysaccharide-transporting ATPase activity
CK627_00720	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
CK627_00725	COG2927	DNA polymerase III (CHI subunit)
CK627_00730	COG0525	valine-tRNA ligase activity
CK627_00735	COG1253	flavin adenine dinucleotide binding
CK627_00740	COG0586	Pfam SNARE associated Golgi protein
CK627_00745	COG1686	Belongs to the peptidase S11 family
CK627_00780	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
CK627_00785	COG0527	aspartate kinase activity
CK627_00790	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
CK627_00800	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
CK627_00805	COG1546	Belongs to the CinA family
CK627_00810	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
CK627_00830	COG3068	Protein conserved in bacteria
CK627_00840	COG0739	heme binding
CK627_00860	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
CK627_00865	COG1121	(ABC) transporter
CK627_00870	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CK627_00875	COG0583	DNA-binding transcription factor activity
CK627_00880	COG0697	spore germination
CK627_00885	COG1573	uracil-dna glycosylase
CK627_00890	COG2962	Rard protein
CK627_00900	COG2827	Endonuclease containing a URI domain
CK627_00915	COG1842	Phage shock protein A
CK627_00920	COG0204	Acyl-transferase
CK627_00940	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CK627_00990	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
CK627_01000	COG0583	DNA-binding transcription factor activity
CK627_01015	COG0187	DNA topoisomerase II activity
CK627_01020	COG1289	transmembrane transporter activity
CK627_01025	COG1566	PFAM secretion protein HlyD family protein
CK627_01040	COG1051	belongs to the nudix hydrolase family
CK627_01045	COG3150	esterase
CK627_01055	COG3151	Protein conserved in bacteria
CK627_01060	COG0494	nUDIX hydrolase
CK627_01065	COG1538	Outer membrane efflux protein
CK627_01070	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
CK627_01070	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
CK627_01075	COG1560	Kdo2-lipid A biosynthetic process
CK627_01090	COG1392	Phosphate transport regulator
CK627_01095	COG0306	phosphate transporter
CK627_01100	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
CK627_01130	COG0583	DNA-binding transcription factor activity
CK627_01135	COG1380	Effector of murein hydrolase LrgA
CK627_01140	COG1346	cytolysis
CK627_01155	COG0617	tRNA 3'-terminal CCA addition
CK627_01160	COG3267	Type II secretory pathway component ExeA
CK627_01160	COG3409	Peptidoglycan-binding domain 1 protein
CK627_01170	COG1194	a g-specific adenine glycosylase
CK627_01175	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
CK627_01185	COG3111	PFAM Bacterial OB fold (BOF) protein
CK627_01190	COG3240	lipase activity
CK627_01200	COG2885	chlorophyll binding
CK627_01200	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
CK627_01205	COG3009	Protein conserved in bacteria
CK627_01210	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
CK627_01210	COG3008	intermembrane lipid transfer
CK627_01215	COG2995	paraquat-inducible protein a
CK627_01225	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CK627_01235	COG3706	GGDEF domain
CK627_01235	COG2203	Gaf domain
CK627_01235	COG4251	negative regulation of phosphorylation
CK627_01235	COG5001	Diguanylate cyclase
CK627_01240	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CK627_01245	COG2813	Specifically methylates the guanine in position
CK627_01250	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
CK627_01255	COG0297	glycogen (starch) synthase activity
CK627_01295	COG1757	Na H antiporter
CK627_01300	COG0583	DNA-binding transcription factor activity
CK627_01305	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
CK627_01310	COG3842	ATPase activity
CK627_01315	COG1176	ABC-type spermidine putrescine transport system, permease component I
CK627_01320	COG1177	transmembrane transport
CK627_01325	COG1012	belongs to the aldehyde dehydrogenase family
CK627_01350	COG0110	maltose O-acetyltransferase activity
CK627_01355	COG0366	Alpha amylase catalytic
CK627_01360	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CK627_01360	COG1263	PTS System
CK627_01365	COG1609	Transcriptional regulator
CK627_01380	COG0252	asparaginase activity
CK627_01395	COG1803	Methylglyoxal synthase
CK627_01420	COG1444	tRNA N-acetyltransferase activity
CK627_01430	COG0784	Response regulator, receiver
CK627_01430	COG0835	chemotaxis
CK627_01470	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
CK627_01475	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
CK627_01490	COG0477	Major facilitator Superfamily
CK627_01495	COG0523	cobalamin synthesis protein
CK627_01505	COG1280	lysine exporter protein (LysE YggA)
CK627_01515	COG1049	propionate catabolic process, 2-methylcitrate cycle
CK627_01520	COG1752	Esterase of the alpha-beta hydrolase superfamily
CK627_01525	COG0840	transmembrane signaling receptor activity
CK627_01530	COG0840	transmembrane signaling receptor activity
CK627_01540	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CK627_01545	COG0508	dehydrogenase complex catalyzes the overall conversion of
CK627_01550	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
CK627_01555	COG2186	Transcriptional regulator
CK627_01585	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
CK627_01590	COG1459	type II secretion system
CK627_01605	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
CK627_01610	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
CK627_01615	COG0494	nUDIX hydrolase
CK627_01625	COG0653	protein targeting
CK627_01635	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
CK627_01640	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
CK627_01645	COG0849	cell division
CK627_01650	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
CK627_01655	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
CK627_01660	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
CK627_01665	COG0772	Belongs to the SEDS family
CK627_01670	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
CK627_01680	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
CK627_01690	COG0768	penicillin binding
CK627_01695	COG3116	cell division
CK627_01700	COG0275	rRNA processing
CK627_01705	COG2001	Belongs to the MraZ family
CK627_01715	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
CK627_01720	COG3107	peptidoglycan biosynthetic process
CK627_01725	COG0792	nuclease activity
CK627_01730	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
CK627_01735	COG2823	Periplasmic or secreted lipoprotein
CK627_01740	COG2969	positive regulation of protein catabolic process
CK627_01745	COG0625	glutathione transferase activity
CK627_01750	COG2857	Cytochrome c1
CK627_01755	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
CK627_01760	COG0723	plastoquinol--plastocyanin reductase activity
CK627_01765	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
CK627_01770	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
CK627_01775	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
CK627_01785	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CK627_01790	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CK627_01825	COG3964	amidohydrolase
CK627_01840	COG3711	transcriptional antiterminator
CK627_01840	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CK627_01845	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CK627_01850	COG1660	Displays ATPase and GTPase activities
CK627_01855	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CK627_01865	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
CK627_01870	COG1137	ATPase activity
CK627_01875	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
CK627_01880	COG3117	lipopolysaccharide transmembrane transporter activity
CK627_01885	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
CK627_01890	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
CK627_01890	COG0517	IMP dehydrogenase activity
CK627_01895	COG1127	ABC transporter
CK627_01900	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
CK627_01905	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
CK627_01910	COG2854	intermembrane phospholipid transfer
CK627_01920	COG5007	Belongs to the BolA IbaG family
CK627_01925	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
CK627_01930	COG0312	modulator of DNA gyrase
CK627_01935	COG3028	Belongs to the UPF0307 family
CK627_01945	COG2926	Belongs to the UPF0265 family
CK627_01975	COG1396	sequence-specific DNA binding
CK627_01980	COG3135	benzoate transporter
CK627_02010	COG3047	cAMP biosynthetic process
CK627_02015	COG3706	GGDEF domain
CK627_02020	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
CK627_02025	COG2197	response regulator
CK627_02055	COG1278	Cold shock
CK627_02060	COG4771	TonB-dependent receptor
CK627_02065	COG5001	Diguanylate cyclase
CK627_02065	COG4251	negative regulation of phosphorylation
CK627_02065	COG2203	Gaf domain
CK627_02065	COG3706	GGDEF domain
CK627_02075	COG0745	RESPONSE REGULATOR receiver
CK627_02095	COG0745	RESPONSE REGULATOR receiver
CK627_02095	COG3706	GGDEF domain
CK627_02105	COG0346	lactoylglutathione lyase activity
CK627_02110	COG0583	DNA-binding transcription factor activity
CK627_02125	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
CK627_02130	COG1074	ATP-dependent DNA helicase activity
CK627_02135	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
CK627_02140	COG2259	Doxx family
CK627_02145	COG1741	Belongs to the pirin family
CK627_02155	COG0583	DNA-binding transcription factor activity
CK627_02180	COG1175	transmembrane transport
CK627_02190	COG3842	ATPase activity
CK627_02200	COG3706	GGDEF domain
CK627_02220	COG1247	-acetyltransferase
CK627_02250	COG0628	permease
CK627_02255	COG4221	oxidoreductase activity
CK627_02260	COG2957	Belongs to the agmatine deiminase family
CK627_02265	COG0583	DNA-binding transcription factor activity
CK627_02270	COG3284	Transcriptional regulator
CK627_02285	COG1461	Dihydroxyacetone kinase
CK627_02290	COG2376	Dihydroxyacetone kinase
CK627_02295	COG2252	PERMEase
CK627_02330	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
CK627_02335	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
CK627_02340	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
CK627_02345	COG0049	tRNA binding
CK627_02350	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
CK627_02355	COG2168	tRNA wobble position uridine thiolation
CK627_02360	COG2923	Belongs to the DsrF TusC family
CK627_02370	COG0251	oxidation-reduction process
CK627_02375	COG2964	Protein conserved in bacteria
CK627_02380	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
CK627_02385	COG0085	RNA polymerase activity
CK627_02390	COG0222	ribosome binding
CK627_02395	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
CK627_02400	COG0081	regulation of translation
CK627_02405	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
CK627_02410	COG0250	Participates in transcription elongation, termination and antitermination
CK627_02415	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
CK627_02425	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
CK627_02450	COG0812	UDP-N-acetylmuramate dehydrogenase activity
CK627_02455	COG0569	domain protein
CK627_02460	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
CK627_02480	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
CK627_02485	COG3005	denitrification pathway
CK627_02490	COG0243	molybdopterin cofactor binding
CK627_02500	COG2205	protein histidine kinase activity
CK627_02505	COG0745	RESPONSE REGULATOR receiver
CK627_02520	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
CK627_02540	COG2204	response regulator
CK627_02550	COG2205	protein histidine kinase activity
CK627_02565	COG1028	Short-chain dehydrogenase reductase Sdr
CK627_02570	COG0516	GMP reductase activity
CK627_02570	COG0517	IMP dehydrogenase activity
CK627_02575	COG5413	integral membrane protein
CK627_02585	COG1522	sequence-specific DNA binding
CK627_02590	COG2502	aspartate--ammonia ligase
CK627_02595	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
CK627_02600	COG0542	response to heat
CK627_02610	COG0564	pseudouridine synthase activity
CK627_02615	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CK627_02620	COG0446	pyridine nucleotide-disulphide oxidoreductase
CK627_02630	COG3681	Belongs to the UPF0597 family
CK627_02640	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
CK627_02645	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
CK627_02650	COG1979	alcohol dehydrogenase
CK627_02655	COG2207	Transcriptional regulator
CK627_02675	COG0688	phosphatidylethanolamine metabolic process
CK627_02690	COG0540	Belongs to the ATCase OTCase family
CK627_02695	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
CK627_02700	COG1438	arginine binding
CK627_02705	COG1288	antiporter activity
CK627_02710	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
CK627_02760	COG3250	beta-galactosidase activity
CK627_02765	COG1609	Transcriptional regulator
CK627_02770	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
CK627_02780	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
CK627_02785	COG2017	converts alpha-aldose to the beta-anomer
CK627_02790	COG0667	Aldo Keto reductase
CK627_02795	COG1968	undecaprenyl-diphosphatase activity
CK627_02800	COG3806	Anti-sigma factor
CK627_02805	COG1595	DNA-templated transcription, initiation
CK627_02825	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
CK627_02830	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
CK627_02835	COG0477	Major facilitator Superfamily
CK627_02845	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CK627_02850	COG2146	nitrite reductase [NAD(P)H] activity
CK627_02855	COG2116	formate transmembrane transporter activity
CK627_02860	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
CK627_02860	COG1648	precorrin-2 dehydrogenase activity
CK627_02865	COG2239	Acts as a magnesium transporter
CK627_02875	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
CK627_02880	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
CK627_02890	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
CK627_02900	COG0514	ATP-dependent DNA helicase (RecQ)
CK627_02905	COG2050	protein possibly involved in aromatic compounds catabolism
CK627_02920	COG2258	MOSC domain
CK627_02925	COG1177	transmembrane transport
CK627_02930	COG1176	ABC-type spermidine putrescine transport system, permease component I
CK627_02935	COG3842	ATPase activity
CK627_02955	COG0174	glutamine synthetase
CK627_02960	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
CK627_02975	COG3045	CreA protein
CK627_02980	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CK627_02985	COG0443	Heat shock 70 kDa protein
CK627_02990	COG3187	Heat shock protein
CK627_03000	COG0366	Alpha amylase catalytic
CK627_03005	COG1086	Polysaccharide biosynthesis protein
CK627_03010	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
CK627_03015	COG1213	nucleotidyl transferase
CK627_03020	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
CK627_03025	COG0574	Belongs to the PEP-utilizing enzyme family
CK627_03025	COG3848	Pyruvate phosphate dikinase
CK627_03030	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
CK627_03040	COG0529	Catalyzes the synthesis of activated sulfate
CK627_03065	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
CK627_03085	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
CK627_03105	COG1442	glycosyl transferase family 8
CK627_03110	COG1215	transferase activity, transferring glycosyl groups
CK627_03125	COG0318	PFAM AMP-dependent synthetase and ligase
CK627_03130	COG1028	Short-chain dehydrogenase reductase Sdr
CK627_03145	COG1083	cytidylyl-transferase
CK627_03155	COG2089	acid synthase
CK627_03175	COG4310	Domain of unknown function (DUF2172)
CK627_03210	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
CK627_03215	COG0745	RESPONSE REGULATOR receiver
CK627_03220	COG2205	protein histidine kinase activity
CK627_03230	COG0281	malic enzyme
CK627_03235	COG0702	epimerase
CK627_03240	COG0254	rRNA binding
CK627_03245	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
CK627_03275	COG0129	dihydroxy-acid dehydratase activity
CK627_03280	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CK627_03285	COG3978	acetolactate synthase activity
CK627_03295	COG0606	chelatase, subunit chli
CK627_03300	COG0204	Acyl-transferase
CK627_03305	COG0204	Acyl-transferase
CK627_03310	COG1683	Conserved Protein
CK627_03320	COG1335	isochorismatase
CK627_03330	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
CK627_03335	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
CK627_03340	COG3639	organic phosphonate transmembrane transporter activity
CK627_03345	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
CK627_03350	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
CK627_03360	COG3084	Protein conserved in bacteria
CK627_03365	COG2203	Gaf domain
CK627_03365	COG3706	GGDEF domain
CK627_03365	COG4251	negative regulation of phosphorylation
CK627_03365	COG5001	Diguanylate cyclase
CK627_03370	COG0789	Transcriptional regulator
CK627_03380	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
CK627_03385	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
CK627_03390	COG1561	YicC-like family, N-terminal region
CK627_03405	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CK627_03415	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CK627_03435	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CK627_03440	COG4605	iron ion homeostasis
CK627_03445	COG4604	ABC transporter, ATP-binding protein
CK627_03450	COG4607	ABC-type enterochelin transport system periplasmic component
CK627_03455	COG4774	siderophore transport
CK627_03475	COG3306	glycosyltransferase involved in LPS biosynthesis
CK627_03490	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CK627_03505	COG1063	alcohol dehydrogenase
CK627_03510	COG3245	cytochrome
CK627_03515	COG5001	Diguanylate cyclase
CK627_03515	COG3300	MHYT domain
CK627_03525	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
CK627_03530	COG2166	iron-sulfur cluster assembly
CK627_03535	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
CK627_03570	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
CK627_03580	COG0583	DNA-binding transcription factor activity
CK627_03595	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
CK627_03600	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
CK627_03605	COG2223	nitrite transmembrane transporter activity
CK627_03610	COG3279	Response regulator of the LytR AlgR family
CK627_03615	COG3275	phosphorelay sensor kinase activity
CK627_03625	COG2223	nitrite transmembrane transporter activity
CK627_03630	COG2081	HI0933 family
CK627_03635	COG1528	Iron-storage protein
CK627_03640	COG2199	diguanylate cyclase activity
CK627_03645	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
CK627_03650	COG0589	response to stress
CK627_03690	COG3642	lipopolysaccharide core region biosynthetic process
CK627_03695	COG0859	PFAM glycosyl transferase family 9
CK627_03710	COG1758	RNA polymerase activity
CK627_03715	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CK627_03720	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CK627_03730	COG2267	carboxylic ester hydrolase activity
CK627_03735	COG0561	phosphatase activity
CK627_03755	COG1840	ABC-type Fe3 transport system, periplasmic component
CK627_03760	COG2271	Major facilitator Superfamily
CK627_03795	COG1309	transcriptional regulator
CK627_03800	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CK627_03805	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CK627_03810	COG4191	Histidine kinase
CK627_03810	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CK627_03815	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CK627_03840	COG2205	protein histidine kinase activity
CK627_03845	COG0745	RESPONSE REGULATOR receiver
CK627_03850	COG2814	Major facilitator Superfamily
CK627_03865	COG3977	Valine--pyruvate aminotransferase
CK627_03870	COG0071	Belongs to the small heat shock protein (HSP20) family
CK627_03875	COG0071	Belongs to the small heat shock protein (HSP20) family
CK627_03880	COG2378	regulation of single-species biofilm formation
CK627_03890	COG0187	DNA topoisomerase II activity
CK627_03900	COG0592	DNA-directed DNA polymerase activity
CK627_03905	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
CK627_03920	COG1126	abc transporter atp-binding protein
CK627_03925	COG0230	Belongs to the bacterial ribosomal protein bL34 family
CK627_03930	COG0594	ribonuclease P activity
CK627_03935	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
CK627_03940	COG0706	membrane insertase activity
CK627_03945	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
CK627_03960	COG1120	ATPase activity
CK627_03965	COG4615	Cyclic peptide transporter
CK627_03970	COG4774	siderophore transport
CK627_03975	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
CK627_03980	COG0445	tRNA wobble uridine modification
CK627_03985	COG0357	Ribosomal RNA small subunit methyltransferase G
CK627_03990	COG1192	Involved in chromosome partitioning
CK627_03995	COG1475	DNA binding
CK627_04005	COG0356	it plays a direct role in the translocation of protons across the membrane
CK627_04015	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
CK627_04020	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
CK627_04025	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
CK627_04030	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
CK627_04035	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
CK627_04040	COG0355	proton-transporting ATP synthase activity, rotational mechanism
CK627_04045	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
CK627_04050	COG4452	Inner membrane protein CreD
CK627_04060	COG2205	protein histidine kinase activity
CK627_04065	COG0745	RESPONSE REGULATOR receiver
CK627_04070	COG1349	DNA-binding transcription factor activity
CK627_04075	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
CK627_04080	COG2771	luxR family
CK627_04090	COG0811	peptide transport
CK627_04095	COG0811	peptide transport
CK627_04100	COG0848	biopolymer transport protein
CK627_04105	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
CK627_04145	COG0402	S-adenosylhomocysteine deaminase activity
CK627_04150	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
CK627_04160	COG3165	ubiquinone biosynthetic process from chorismate
CK627_04165	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
CK627_04175	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CK627_04180	COG0805	protein transport
CK627_04185	COG0084	hydrolase, TatD family'
CK627_04205	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CK627_04210	COG0742	ribosomal rna small subunit methyltransferase
CK627_04225	COG0248	Ppx GppA phosphatase
CK627_04230	COG0513	Belongs to the DEAD box helicase family
CK627_04235	COG3118	belongs to the thioredoxin family
CK627_04240	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
CK627_04250	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
CK627_04275	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CK627_04305	COG0559	Belongs to the binding-protein-dependent transport system permease family
CK627_04315	COG1609	Transcriptional regulator
CK627_04330	COG2188	Transcriptional regulator
CK627_04335	COG0348	domain, Protein
CK627_04340	COG0814	amino acid
CK627_04375	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
CK627_04385	COG0751	glycine-tRNA ligase activity
CK627_04390	COG0752	glycyl-tRNA synthetase alpha subunit
CK627_04395	COG2818	Glycosylase
CK627_04405	COG2885	chlorophyll binding
CK627_04410	COG0251	oxidation-reduction process
CK627_04415	COG0425	Belongs to the sulfur carrier protein TusA family
CK627_04430	COG2205	protein histidine kinase activity
CK627_04435	COG0745	RESPONSE REGULATOR receiver
CK627_04440	COG0183	Belongs to the thiolase family
CK627_04445	COG1250	3-hydroxyacyl-CoA dehydrogenase
CK627_04445	COG1024	Enoyl-CoA hydratase
CK627_04450	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CK627_04455	COG0006	proline dipeptidase activity
CK627_04460	COG1739	Uncharacterized protein family UPF0029
CK627_04465	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
CK627_04470	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
CK627_04500	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CK627_04500	COG0045	succinate-CoA ligase (ADP-forming) activity
CK627_04500	COG1042	CoA-binding domain protein
CK627_04515	COG0583	DNA-binding transcription factor activity
CK627_04520	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
CK627_04525	COG0166	Belongs to the GPI family
CK627_04540	COG0668	transmembrane transport
CK627_04545	COG1309	transcriptional regulator
CK627_04550	COG0756	dUTP diphosphatase activity
CK627_04555	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
CK627_04560	COG2003	Belongs to the UPF0758 family
CK627_04565	COG0227	Belongs to the bacterial ribosomal protein bL28 family
CK627_04570	COG0267	Belongs to the bacterial ribosomal protein bL33 family
CK627_04580	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
CK627_04585	COG2990	Protein conserved in bacteria
CK627_04590	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
CK627_04595	COG0859	PFAM glycosyl transferase family 9
CK627_04600	COG0463	Glycosyl transferase, family 2
CK627_04605	COG0859	PFAM glycosyl transferase family 9
CK627_04610	COG1519	Transferase
CK627_04630	COG1609	Transcriptional regulator
CK627_04635	COG0604	alcohol dehydrogenase
CK627_04655	COG1580	Controls the rotational direction of flagella during chemotaxis
CK627_04660	COG3161	chorismate lyase activity
CK627_04665	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
CK627_04670	COG2937	Belongs to the GPAT DAPAT family
CK627_04675	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
CK627_04695	COG0534	Mate efflux family protein
CK627_04700	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
CK627_04705	COG2205	protein histidine kinase activity
CK627_04710	COG0745	RESPONSE REGULATOR receiver
CK627_04720	COG1045	serine acetyltransferase
CK627_04730	COG3074	FtsZ-dependent cytokinesis
CK627_04735	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
CK627_04740	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CK627_04740	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CK627_04745	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
CK627_04785	COG1609	Transcriptional regulator
CK627_04790	COG3250	beta-galactosidase activity
CK627_04795	COG2731	YhcH YjgK YiaL family protein
CK627_04800	COG0531	amino acid
CK627_04805	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CK627_04810	COG0531	amino acid
CK627_04815	COG0385	Bile acid
CK627_04820	COG1262	PFAM Formylglycine-generating sulfatase enzyme
CK627_04840	COG0583	DNA-binding transcription factor activity
CK627_04865	COG0210	DNA helicase
CK627_04875	COG1943	Transposase
CK627_04895	COG0583	DNA-binding transcription factor activity
CK627_04925	COG3161	chorismate lyase activity
CK627_04960	COG1280	lysine exporter protein (LysE YggA)
CK627_04965	COG2391	methyltransferase activity
CK627_04975	COG1280	lysine exporter protein (LysE YggA)
CK627_04985	COG2962	Rard protein
CK627_04995	COG1012	belongs to the aldehyde dehydrogenase family
CK627_05000	COG1396	sequence-specific DNA binding
CK627_05015	COG0518	GMP synthase (glutamine-hydrolyzing) activity
CK627_05015	COG0519	Catalyzes the synthesis of GMP from XMP
CK627_05020	COG0686	Belongs to the AlaDH PNT family
CK627_05025	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CK627_05045	COG1322	Protein conserved in bacteria
CK627_05050	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
CK627_05055	COG0569	domain protein
CK627_05060	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CK627_05060	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
CK627_05065	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
CK627_05070	COG0242	peptide deformylase activity
CK627_05080	COG0758	DNA mediated transformation
CK627_05085	COG2922	Belongs to the Smg family
CK627_05090	COG0551	DNA topoisomerase type I activity
CK627_05100	COG0009	L-threonylcarbamoyladenylate synthase
CK627_05105	COG0408	coproporphyrinogen oxidase activity
CK627_05110	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
CK627_05120	COG0218	Necessary for normal cell division and for the maintenance of normal septation
CK627_05135	COG3078	GTPase activator activity
CK627_05145	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CK627_05150	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
CK627_05155	COG2204	response regulator
CK627_05160	COG3852	Histidine kinase
CK627_05170	COG0174	glutamine synthetase
CK627_05180	COG1295	ribonuclease BN
CK627_05185	COG1295	ribonuclease BN
CK627_05190	COG1490	D-aminoacyl-tRNA deacylase activity
CK627_05200	COG0456	acetyltransferase
CK627_05210	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
CK627_05215	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CK627_05220	COG2610	gluconate transmembrane transporter activity
CK627_05225	COG3265	gluconokinase activity
CK627_05230	COG0129	dihydroxy-acid dehydratase activity
CK627_05235	COG0800	Aldolase
CK627_05240	COG1609	Transcriptional regulator
CK627_05250	COG4942	peptidase
CK627_05255	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
CK627_05260	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CK627_05265	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
CK627_05270	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
CK627_05275	COG0316	Belongs to the HesB IscA family
CK627_05275	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
CK627_05280	COG1040	competence protein
CK627_05285	COG0596	Alpha beta hydrolase
CK627_05305	COG2183	response to ionizing radiation
CK627_05310	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CK627_05315	COG0745	RESPONSE REGULATOR receiver
CK627_05330	COG0051	transcription antitermination factor activity, RNA binding
CK627_05335	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
CK627_05340	COG0088	Forms part of the polypeptide exit tunnel
CK627_05345	COG0089	rRNA binding
CK627_05350	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
CK627_05355	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
CK627_05360	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
CK627_05365	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
CK627_05370	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
CK627_05375	COG0255	Belongs to the universal ribosomal protein uL29 family
CK627_05380	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
CK627_05385	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
CK627_05390	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
CK627_05395	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
CK627_05400	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
CK627_05405	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
CK627_05410	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
CK627_05415	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
CK627_05420	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
CK627_05425	COG1841	ribosomal large subunit assembly
CK627_05430	COG0200	Binds to the 23S rRNA
CK627_05435	COG0201	protein transport
CK627_05440	COG0257	Belongs to the bacterial ribosomal protein bL36 family
CK627_05445	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
CK627_05450	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
CK627_05455	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
CK627_05460	COG0202	RNA polymerase activity
CK627_05465	COG0203	ribosomal protein L17
CK627_05515	COG2249	NAD(P)H dehydrogenase (quinone) activity
CK627_05520	COG0583	DNA-binding transcription factor activity
CK627_05525	COG4221	oxidoreductase activity
CK627_05540	COG1770	oligopeptidase
CK627_05565	COG3714	YhhN family
CK627_05590	COG1301	dicarboxylic acid transport
CK627_05600	COG2095	MarC family integral membrane protein
CK627_05620	COG0741	lytic transglycosylase activity
CK627_05625	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CK627_05650	COG0742	ribosomal rna small subunit methyltransferase
CK627_05655	COG0552	protein localization to endoplasmic reticulum
CK627_05660	COG2884	Cell division ATP-binding protein ftsE
CK627_05665	COG2177	Part of the ABC transporter FtsEX involved in
CK627_05675	COG0288	reversible hydration of carbon dioxide
CK627_05680	COG2188	Transcriptional regulator
CK627_05685	COG1228	amidohydrolase
CK627_05690	COG0010	Belongs to the arginase family
CK627_05695	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
CK627_05700	COG2986	histidine ammonia-lyase
CK627_05705	COG0387	Pfam Sodium calcium exchanger
CK627_05710	COG2200	EAL domain
CK627_05715	COG2200	EAL domain
CK627_05715	COG2199	diguanylate cyclase activity
CK627_05765	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
CK627_05770	COG1459	type II secretion system
CK627_05790	COG4968	Prepilin-type N-terminal cleavage methylation domain
CK627_05815	COG1077	Cell shape determining protein MreB Mrl
CK627_05820	COG1792	Involved in formation and maintenance of cell shape
CK627_05825	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
CK627_05830	COG0424	maF-like protein
CK627_05835	COG1530	ribonuclease E activity
CK627_05840	COG3164	Protein of unknown function
CK627_05855	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CK627_05860	COG0312	modulator of DNA gyrase
CK627_05875	COG0477	Major facilitator Superfamily
CK627_05885	COG3437	response regulator, receiver
CK627_05890	COG5002	protein histidine kinase activity
CK627_05890	COG0784	Response regulator, receiver
CK627_05890	COG2205	protein histidine kinase activity
CK627_05895	COG2172	sigma factor antagonist activity
CK627_05900	COG1366	Belongs to the anti-sigma-factor antagonist family
CK627_05920	COG3700	Belongs to the class B bacterial acid phosphatase family
CK627_05925	COG2321	neutral zinc metallopeptidase
CK627_05935	COG1639	'signal transduction protein
CK627_05960	COG0189	ligase activity
CK627_05970	COG0745	RESPONSE REGULATOR receiver
CK627_05985	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
CK627_05990	COG0352	thiamine-phosphate diphosphorylase activity
CK627_05995	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
CK627_06005	COG2022	thiamine diphosphate biosynthetic process
CK627_06010	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
CK627_06035	COG3417	Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1B (PBP1b)
CK627_06055	COG3706	GGDEF domain
CK627_06060	COG0814	amino acid
CK627_06065	COG3932	Exopolysaccharide synthesis, ExoD
CK627_06085	COG1733	regulation of RNA biosynthetic process
CK627_06090	COG0456	acetyltransferase
CK627_06125	COG1494	fructose-1,6-bisphosphatase
CK627_06140	COG2959	enzyme of heme biosynthesis
CK627_06150	COG0181	hydroxymethylbilane synthase activity
CK627_06155	COG3072	Adenylate cyclase
CK627_06160	COG0400	carboxylic ester hydrolase activity
CK627_06165	COG1965	Belongs to the frataxin family
CK627_06170	COG0019	diaminopimelate decarboxylase activity
CK627_06175	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
CK627_06190	COG1011	Hydrolase
CK627_06210	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
CK627_06215	COG0561	phosphatase activity
CK627_06230	COG1129	ABC transporter
CK627_06230	COG0842	Transport permease protein
CK627_06240	COG1058	Belongs to the CinA family
CK627_06240	COG1546	Belongs to the CinA family
CK627_06245	COG1418	mRNA catabolic process
CK627_06250	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
CK627_06260	COG1522	sequence-specific DNA binding
CK627_06265	COG1368	sulfuric ester hydrolase activity
CK627_06285	COG1285	pathogenesis
CK627_06305	COG4221	oxidoreductase activity
CK627_06320	COG1979	alcohol dehydrogenase
CK627_06330	COG2873	o-acetylhomoserine
CK627_06355	COG5380	lipid catabolic process
CK627_06360	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
CK627_06375	COG2949	membrane
CK627_06380	COG3291	Pkd domain containing protein
CK627_06390	COG3539	Fimbrial protein
CK627_06400	COG3188	usher protein
CK627_06405	COG3121	Chaperone
CK627_06425	COG0318	PFAM AMP-dependent synthetase and ligase
CK627_06430	COG1441	menaquinone biosynthetic process
CK627_06435	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
CK627_06440	COG0596	Alpha beta hydrolase
CK627_06445	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
CK627_06450	COG1169	isochorismate synthase
CK627_06455	COG1575	Belongs to the MenA family. Type 1 subfamily
CK627_06480	COG0513	Belongs to the DEAD box helicase family
CK627_06485	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
CK627_06505	COG1671	Belongs to the UPF0178 family
CK627_06530	COG3263	regulation of cellular component size
CK627_06535	COG3722	fumarate hydratase activity
CK627_06540	COG0246	Mannitol dehydrogenase
CK627_06545	COG2213	PTS system mannitol-specific
CK627_06545	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
CK627_06555	COG1309	transcriptional regulator
CK627_06560	COG4776	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction
CK627_06570	COG3916	Acyl-homoserine-lactone synthase
CK627_06575	COG2771	luxR family
CK627_06590	COG3133	Outer membrane lipoprotein
CK627_06595	COG0456	acetyltransferase
CK627_06620	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
CK627_06630	COG3031	protein transport across the cell outer membrane
CK627_06640	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
CK627_06645	COG1459	type II secretion system
CK627_06650	COG2165	general secretion pathway protein
CK627_06660	COG2165	general secretion pathway protein
CK627_06665	COG4795	General secretion pathway protein
CK627_06670	COG3156	type II secretion system protein K
CK627_06680	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
CK627_06695	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
CK627_06705	COG1902	pentaerythritol trinitrate reductase activity
CK627_06710	COG1011	Hydrolase
CK627_06715	COG0494	nUDIX hydrolase
CK627_06720	COG1218	3'(2'),5'-bisphosphate nucleotidase
CK627_06725	COG0814	amino acid
CK627_06730	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CK627_06735	COG2207	Transcriptional regulator
CK627_06735	COG3708	Transcriptional regulator
CK627_06745	COG0626	cystathionine gamma-synthase activity
CK627_06750	COG0527	aspartate kinase activity
CK627_06750	COG0460	homoserine dehydrogenase
CK627_06755	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
CK627_06765	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
CK627_06770	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
CK627_06780	COG0137	argininosuccinate synthase activity
CK627_06790	COG0165	Argininosuccinate lyase
CK627_06815	COG0110	maltose O-acetyltransferase activity
CK627_06820	COG3174	membrane
CK627_06825	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
CK627_06835	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
CK627_06840	COG4208	sulfate ABC transporter
CK627_06845	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
CK627_06850	COG0583	DNA-binding transcription factor activity
CK627_06855	COG3397	chitin binding
CK627_06895	COG4946	Tricorn protease homolog
CK627_06895	COG0793	Belongs to the peptidase S41A family
CK627_06915	COG1328	CTP reductase activity
CK627_06920	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
CK627_06935	COG1448	Aminotransferase
CK627_06975	COG0513	Belongs to the DEAD box helicase family
CK627_06990	COG3568	Endonuclease Exonuclease Phosphatase
CK627_07005	COG3112	Uncharacterised protein family (UPF0231)
CK627_07010	COG3835	regulator
CK627_07015	COG2610	gluconate transmembrane transporter activity
CK627_07020	COG1929	Belongs to the glycerate kinase type-1 family
CK627_07040	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
CK627_07055	COG0347	Belongs to the P(II) protein family
CK627_07060	COG1840	ABC-type Fe3 transport system, periplasmic component
CK627_07070	COG3842	ATPase activity
CK627_07075	COG2837	iron assimilation
CK627_07080	COG1438	arginine binding
CK627_07085	COG1126	abc transporter atp-binding protein
CK627_07090	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CK627_07095	COG4215	(ABC) transporter
CK627_07100	COG4160	amino acid transport
CK627_07105	COG0039	L-malate dehydrogenase activity
CK627_07110	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
CK627_07115	COG1017	nitric oxide dioxygenase activity
CK627_07115	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CK627_07120	COG1959	2 iron, 2 sulfur cluster binding
CK627_07125	COG4536	flavin adenine dinucleotide binding
CK627_07130	COG4137	Cytochrome C assembly protein
CK627_07135	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
CK627_07140	COG0228	four-way junction DNA binding
CK627_07145	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
CK627_07150	COG0336	Belongs to the RNA methyltransferase TrmD family
CK627_07155	COG0335	large ribosomal subunit rRNA binding
CK627_07165	COG3066	DNA modification
CK627_07170	COG1051	belongs to the nudix hydrolase family
CK627_07180	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
CK627_07185	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
CK627_07190	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
CK627_07200	COG0583	DNA-binding transcription factor activity
CK627_07205	COG0640	Transcriptional regulator
CK627_07210	COG0268	Binds directly to 16S ribosomal RNA
CK627_07215	COG0728	peptidoglycan biosynthetic process
CK627_07220	COG0196	riboflavin kinase activity
CK627_07225	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
CK627_07230	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
CK627_07235	COG1047	Peptidyl-prolyl cis-trans
CK627_07240	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
CK627_07300	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
CK627_07300	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CK627_07315	COG1854	S-ribosylhomocysteine lyase activity
CK627_07320	COG3706	GGDEF domain
CK627_07325	COG0557	exoribonuclease II activity
CK627_07365	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CK627_07375	COG2153	protein acetylation
CK627_07380	COG0697	spore germination
CK627_07400	COG2814	Major facilitator Superfamily
CK627_07410	COG0583	DNA-binding transcription factor activity
CK627_07420	COG1914	H( )-stimulated, divalent metal cation uptake system
CK627_07425	COG0360	Binds together with S18 to 16S ribosomal RNA
CK627_07430	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
CK627_07435	COG0359	binds to the 23S rRNA
CK627_07440	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CK627_07470	COG1238	metal cluster binding
CK627_07475	COG0612	Peptidase, M16
CK627_07480	COG2918	glutathione biosynthetic process
CK627_07485	COG1022	Amp-dependent synthetase and ligase
CK627_07495	COG0456	acetyltransferase
CK627_07505	COG0714	Associated with various cellular activities
CK627_07525	COG5001	Diguanylate cyclase
CK627_07535	COG3706	GGDEF domain
CK627_07535	COG0745	RESPONSE REGULATOR receiver
CK627_07555	COG1902	pentaerythritol trinitrate reductase activity
CK627_07565	COG2852	Protein conserved in bacteria
CK627_07575	COG2957	Belongs to the agmatine deiminase family
CK627_07580	COG0154	amidase activity
CK627_07595	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CK627_07600	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
CK627_07610	COG0513	Belongs to the DEAD box helicase family
CK627_07635	COG1912	Pfam S-adenosyl-l-methionine hydroxide adenosyltransferase
CK627_07640	COG1858	cytochrome C peroxidase
CK627_07665	COG2070	2-Nitropropane dioxygenase
CK627_07700	COG2205	protein histidine kinase activity
CK627_07705	COG0745	RESPONSE REGULATOR receiver
CK627_07710	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CK627_07715	COG0577	efflux transmembrane transporter activity
CK627_07715	COG1136	(ABC) transporter
CK627_07720	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CK627_07725	COG1126	abc transporter atp-binding protein
CK627_07730	COG0765	amino acid transport
CK627_07735	COG0765	amino acid transport
CK627_07740	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
CK627_07745	COG1505	serine-type exopeptidase activity
CK627_07760	COG1028	Short-chain dehydrogenase reductase Sdr
CK627_07765	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
CK627_07780	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CK627_07785	COG4991	sh3 domain protein
CK627_07800	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
CK627_07805	COG1940	carbohydrate kinase activity
CK627_07810	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
CK627_07815	COG0126	phosphoglycerate kinase activity
CK627_07825	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CK627_07870	COG0354	folic acid binding
CK627_07875	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
CK627_07890	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
CK627_07895	COG1595	DNA-templated transcription, initiation
CK627_07900	COG3073	An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E
CK627_07915	COG0481	GTPase activity
CK627_07920	COG0681	Belongs to the peptidase S26 family
CK627_07925	COG0571	ribonuclease III activity
CK627_07935	COG1381	Involved in DNA repair and RecF pathway recombination
CK627_07940	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
CK627_07955	COG4821	SIS domain
CK627_07960	COG3716	PTS system mannose fructose sorbose family IID component
CK627_07965	COG3715	PTS system
CK627_07970	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CK627_07980	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
CK627_07985	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
CK627_07990	COG2222	sugar isomerase
CK627_08000	COG1349	DNA-binding transcription factor activity
CK627_08005	COG3023	N-Acetylmuramoyl-L-alanine amidase
CK627_08010	COG4807	Protein conserved in bacteria
CK627_08020	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
CK627_08025	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CK627_08030	COG3956	TIGRFAM MazG family protein
CK627_08035	COG0504	CTP synthase activity
CK627_08040	COG0148	phosphopyruvate hydratase activity
CK627_08045	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
CK627_08050	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
CK627_08060	COG0585	pseudouridine synthase activity
CK627_08065	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
CK627_08070	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
CK627_08075	COG1238	metal cluster binding
CK627_08080	COG4942	peptidase
CK627_08080	COG1388	LysM domain
CK627_08090	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
CK627_08095	COG0828	Belongs to the bacterial ribosomal protein bS21 family
CK627_08100	COG1610	YqeY-like protein
CK627_08105	COG0358	DNA primase activity
CK627_08110	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CK627_08190	COG0151	Belongs to the GarS family
CK627_08195	COG0138	bifunctional purine biosynthesis protein purh
CK627_08205	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
CK627_08210	COG3036	rescue of stalled ribosome
CK627_08215	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CK627_08220	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
CK627_08230	COG0673	inositol 2-dehydrogenase activity
CK627_08240	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CK627_08245	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CK627_08250	COG3227	Zinc metalloprotease (Elastase)
CK627_08260	COG0477	Major facilitator Superfamily
CK627_08270	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
CK627_08275	COG1027	Aspartate ammonia-lyase
CK627_08280	COG3030	protein affecting phage T7 exclusion by the F plasmid
CK627_08290	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
CK627_08295	COG0459	protein refolding
CK627_08305	COG5001	Diguanylate cyclase
CK627_08305	COG3300	MHYT domain
CK627_08320	COG0784	Response regulator, receiver
CK627_08320	COG0835	chemotaxis
CK627_08325	COG2755	lipolytic protein G-D-S-L family
CK627_08330	COG4181	ATPase activity
CK627_08335	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
CK627_08340	COG1090	epimerase
CK627_08345	COG2200	EAL domain
CK627_08350	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CK627_08355	COG2234	aminopeptidase activity
CK627_08355	COG4935	Belongs to the peptidase S8 family
CK627_08360	COG0220	tRNA (guanine-N7-)-methyltransferase activity
CK627_08365	COG3171	Protein conserved in bacteria
CK627_08370	COG2066	Belongs to the glutaminase family
CK627_08375	COG2897	thiosulfate sulfurtransferase activity
CK627_08380	COG1404	Belongs to the peptidase S8 family
CK627_08390	COG1132	(ABC) transporter
CK627_08415	COG4412	M6 family metalloprotease domain protein
CK627_08415	COG3291	Pkd domain containing protein
CK627_08420	COG3076	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome
CK627_08425	COG3300	MHYT domain
CK627_08425	COG5001	Diguanylate cyclase
CK627_08445	COG4628	conserved protein (DUF2132)
CK627_08450	COG0688	phosphatidylethanolamine metabolic process
CK627_08455	COG1162	GTPase activity
CK627_08460	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
CK627_08500	COG1278	Cold shock
CK627_08510	COG0840	transmembrane signaling receptor activity
CK627_08515	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CK627_08520	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CK627_08570	COG0848	biopolymer transport protein
CK627_08575	COG0811	peptide transport
CK627_08580	COG0811	peptide transport
CK627_08595	COG4174	ABC transporter (Permease)
CK627_08600	COG4239	(ABC) transporter, permease
CK627_08610	COG0444	Belongs to the ABC transporter superfamily
CK627_08615	COG4608	Belongs to the ABC transporter superfamily
CK627_08630	COG2195	Cleaves the N-terminal amino acid of tripeptides
CK627_08640	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
CK627_08660	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
CK627_08690	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CK627_08695	COG2313	pseudouridylate synthase activity
CK627_08705	COG1858	cytochrome C peroxidase
CK627_08740	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CK627_08745	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CK627_08760	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
CK627_08770	COG2986	histidine ammonia-lyase
CK627_08795	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CK627_08805	COG1028	Short-chain dehydrogenase reductase Sdr
CK627_08810	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CK627_08820	COG0521	Mo-molybdopterin cofactor biosynthetic process
CK627_08830	COG2966	Psort location CytoplasmicMembrane, score
CK627_08835	COG3610	response to peptide
CK627_08845	COG4175	Glycine betaine
CK627_08850	COG4176	ABC-type proline glycine betaine transport system permease component
CK627_08855	COG2113	Glycine betaine
CK627_08860	COG0175	sulfate reduction
CK627_08865	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CK627_08870	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
CK627_08875	COG0384	phenazine biosynthesis protein PhzF
CK627_08880	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
CK627_08895	COG0786	glutamate:sodium symporter activity
CK627_08900	COG0252	asparaginase activity
CK627_08905	COG3139	Protein of unknown function (DUF1315)
CK627_08925	COG0616	signal peptide processing
CK627_08930	COG0446	pyridine nucleotide-disulphide oxidoreductase
CK627_08930	COG1902	pentaerythritol trinitrate reductase activity
CK627_08940	COG0778	Nitroreductase
CK627_08950	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CK627_08955	COG2264	protein methyltransferase activity
CK627_08960	COG0604	alcohol dehydrogenase
CK627_08965	COG0583	DNA-binding transcription factor activity
CK627_08970	COG1263	PTS System
CK627_08970	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CK627_08970	COG2190	(PTS) system
CK627_08975	COG4145	pantothenate transmembrane transporter activity
CK627_08980	COG3924	membrane
CK627_08985	COG0439	Biotin carboxylase
CK627_08990	COG0511	ligase activity, forming carbon-carbon bonds
CK627_08995	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
CK627_09000	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CK627_09010	COG3300	MHYT domain
CK627_09010	COG5001	Diguanylate cyclase
CK627_09030	COG3381	protein complex oligomerization
CK627_09040	COG3005	denitrification pathway
CK627_09045	COG0745	RESPONSE REGULATOR receiver
CK627_09055	COG1879	ABC-type sugar transport system periplasmic component
CK627_09060	COG2205	protein histidine kinase activity
CK627_09060	COG0784	Response regulator, receiver
CK627_09060	COG2198	Histidine kinase
CK627_09070	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
CK627_09085	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
CK627_09090	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CK627_09090	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CK627_09105	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
CK627_09110	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CK627_09115	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
CK627_09120	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
CK627_09125	COG4172	Belongs to the ABC transporter superfamily
CK627_09145	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
CK627_09150	COG0142	geranyltranstransferase activity
CK627_09155	COG1722	exodeoxyribonuclease VII activity
CK627_09160	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
CK627_09165	COG1360	Flagellar Motor Protein
CK627_09170	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CK627_09180	COG1534	Rna-binding protein
CK627_09185	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
CK627_09190	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CK627_09195	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
CK627_09200	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CK627_09205	COG0149	triose-phosphate isomerase activity
CK627_09210	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
CK627_09225	COG0779	Required for maturation of 30S ribosomal subunits
CK627_09230	COG0195	Participates in both transcription termination and antitermination
CK627_09235	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
CK627_09240	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
CK627_09245	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
CK627_09250	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
CK627_09255	COG1185	polyribonucleotide nucleotidyltransferase activity
CK627_09260	COG2211	Major facilitator Superfamily
CK627_09265	COG3706	GGDEF domain
CK627_09270	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
CK627_09280	COG0114	fumarate hydratase activity
CK627_09325	COG0312	modulator of DNA gyrase
CK627_09330	COG0312	modulator of DNA gyrase
CK627_09335	COG0716	FMN binding
CK627_09340	COG4974	Belongs to the 'phage' integrase family
CK627_09345	COG2203	Gaf domain
CK627_09345	COG2199	diguanylate cyclase activity
CK627_09350	COG1970	mechanosensitive ion channel activity
CK627_09360	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
CK627_09365	COG0789	Transcriptional regulator
CK627_09385	COG3545	Serine hydrolase
CK627_09415	COG0270	DNA (cytosine-5-)-methyltransferase activity
CK627_09425	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
CK627_09430	COG0321	lipoyl(octanoyl) transferase activity
CK627_09435	COG2921	Belongs to the UPF0250 family
CK627_09440	COG1686	Belongs to the peptidase S11 family
CK627_09445	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
CK627_09450	COG2951	lytic endotransglycosylase activity
CK627_09455	COG0772	Belongs to the SEDS family
CK627_09460	COG0768	penicillin binding
CK627_09465	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
CK627_09470	COG0799	negative regulation of ribosome biogenesis
CK627_09475	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
CK627_09490	COG0495	leucyl-tRNA aminoacylation
CK627_09495	COG2888	peptidyl-tyrosine sulfation
CK627_09500	COG0815	Transfers the fatty acyl group on membrane lipoproteins
CK627_09505	COG4535	Mg2 and Co2 transporter CorC
CK627_09510	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
CK627_09515	COG1702	phosphate starvation-inducible protein PhoH
CK627_09520	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CK627_09525	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CK627_09530	COG1335	isochorismatase
CK627_09540	COG3706	GGDEF domain
CK627_09555	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CK627_09565	COG3706	GGDEF domain
CK627_09575	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CK627_09585	COG3647	Membrane
CK627_09590	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
CK627_09600	COG0516	GMP reductase activity
CK627_09610	COG0642	Histidine kinase
CK627_09615	COG0745	RESPONSE REGULATOR receiver
CK627_09650	COG3214	Protein conserved in bacteria
CK627_09675	COG3029	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
CK627_09680	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
CK627_09685	COG1053	succinate dehydrogenase
CK627_09700	COG0584	glycerophosphoryl diester phosphodiesterase
CK627_09705	COG3264	Mechanosensitive ion channel
CK627_09705	COG1511	domain protein
CK627_09715	COG0739	heme binding
CK627_09730	COG0583	DNA-binding transcription factor activity
CK627_09750	COG0583	DNA-binding transcription factor activity
CK627_09755	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
CK627_09785	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
CK627_09790	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
CK627_09800	COG0338	D12 class N6 adenine-specific DNA methyltransferase
CK627_09805	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
CK627_09815	COG0180	Tryptophanyl-tRNA synthetase
CK627_09830	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CK627_09840	COG1012	belongs to the aldehyde dehydrogenase family
CK627_09850	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CK627_09860	COG0674	pyruvate-flavodoxin oxidoreductase activity
CK627_09860	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CK627_09860	COG1013	pyruvate-flavodoxin oxidoreductase activity
CK627_09860	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
CK627_09890	COG0488	(ABC) transporter
CK627_09905	COG0366	Alpha amylase catalytic
CK627_09925	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
CK627_09935	COG0490	domain, Protein
CK627_09935	COG0471	metal ion transport
CK627_09980	COG0012	GTP binding
CK627_09985	COG0193	aminoacyl-tRNA hydrolase activity
CK627_09990	COG0737	Belongs to the 5'-nucleotidase family
CK627_09995	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
CK627_10005	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
CK627_10010	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
CK627_10015	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
CK627_10020	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
CK627_10025	COG2890	protein-(glutamine-N5) methyltransferase activity
CK627_10035	COG2912	Transglutaminase-like superfamily
CK627_10040	COG2877	3-deoxy-8-phosphooctulonate synthase activity
CK627_10045	COG1301	dicarboxylic acid transport
CK627_10055	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
CK627_10070	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
CK627_10075	COG1115	amino acid carrier protein
CK627_10090	COG0714	Associated with various cellular activities
CK627_10100	COG3104	oligopeptide transport
CK627_10105	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
CK627_10110	COG1678	Uncharacterized ACR, COG1678
CK627_10120	COG0189	ligase activity
CK627_10125	COG1385	rRNA (uridine-N3-)-methyltransferase activity
CK627_10135	COG3091	SprT-like family
CK627_10145	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
CK627_10165	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
CK627_10170	COG0739	heme binding
CK627_10175	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
CK627_10180	COG3408	Glycogen debranching enzyme
CK627_10180	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
CK627_10190	COG1881	PFAM PEBP family protein
CK627_10200	COG0583	DNA-binding transcription factor activity
CK627_10210	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
CK627_10220	COG0583	DNA-binding transcription factor activity
CK627_10225	COG1028	Short-chain dehydrogenase reductase Sdr
CK627_10230	COG0616	signal peptide processing
CK627_10235	COG3724	N-succinylarginine dihydrolase activity
CK627_10240	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
CK627_10255	COG0840	transmembrane signaling receptor activity
CK627_10265	COG2971	BadF BadG BcrA BcrD
CK627_10275	COG4608	Belongs to the ABC transporter superfamily
CK627_10280	COG0444	Belongs to the ABC transporter superfamily
CK627_10285	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CK627_10290	COG0601	transmembrane transport
CK627_10295	COG4166	transmembrane transport
CK627_10340	COG3220	belongs to the UPF0276 family
CK627_10370	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
CK627_10375	COG1289	transmembrane transporter activity
CK627_10380	COG0303	'Molybdopterin
CK627_10385	COG0746	molybdenum cofactor guanylyltransferase activity
CK627_10395	COG4662	Binding-protein-dependent transport system inner membrane component
CK627_10405	COG2204	response regulator
CK627_10410	COG3852	Histidine kinase
CK627_10415	COG1910	domain protein
CK627_10420	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
CK627_10455	COG3383	formate dehydrogenase (NAD+) activity
CK627_10455	COG3383	formate dehydrogenase (NAD+) activity
CK627_10460	COG0437	4 iron, 4 sulfur cluster binding
CK627_10470	COG0281	malic enzyme
CK627_10490	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CK627_10505	COG2706	6-phosphogluconolactonase activity
CK627_10515	COG1196	nuclear chromosome segregation
CK627_10515	COG3264	Mechanosensitive ion channel
CK627_10520	COG0469	pyruvate kinase activity
CK627_10535	COG4651	solute:proton antiporter activity
CK627_10535	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
CK627_10545	COG2974	May be involved in recombination
CK627_10555	COG0420	3'-5' exonuclease activity
CK627_10565	COG3038	cytochrome b561
CK627_10570	COG0745	RESPONSE REGULATOR receiver
CK627_10570	COG3706	GGDEF domain
CK627_10575	COG2190	(PTS) system
CK627_10580	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CK627_10585	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CK627_10590	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
CK627_10595	COG0542	response to heat
CK627_10610	COG3437	response regulator, receiver
CK627_10610	COG2770	Histidine kinase
CK627_10615	COG1720	tRNA m6t6A37 methyltransferase activity
CK627_10635	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
CK627_10640	COG4988	ABC transporter
CK627_10655	COG0745	RESPONSE REGULATOR receiver
CK627_10665	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
CK627_10680	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
CK627_10685	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
CK627_10695	COG0083	homoserine kinase activity
CK627_10700	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
CK627_10705	COG4319	ketosteroid isomerase
CK627_10720	COG0488	(ABC) transporter
CK627_10730	COG0813	purine-nucleoside phosphorylase activity
CK627_10745	COG2205	protein histidine kinase activity
CK627_10745	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CK627_10750	COG3706	GGDEF domain
CK627_10750	COG5001	Diguanylate cyclase
CK627_10750	COG4251	negative regulation of phosphorylation
CK627_10750	COG2203	Gaf domain
CK627_10755	COG2205	protein histidine kinase activity
CK627_10755	COG5002	protein histidine kinase activity
CK627_10755	COG0784	Response regulator, receiver
CK627_10760	COG3384	dioxygenase
CK627_10770	COG1283	sodium-dependent phosphate transmembrane transporter activity
CK627_10780	COG0531	amino acid
CK627_10785	COG0531	amino acid
CK627_10800	COG1396	sequence-specific DNA binding
CK627_10800	COG1917	Cupin 2, conserved barrel domain protein
CK627_10805	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CK627_10825	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
CK627_10830	COG2375	cellular response to nickel ion
CK627_10835	COG1538	Outer membrane efflux protein
CK627_10840	COG0577	efflux transmembrane transporter activity
CK627_10840	COG1136	(ABC) transporter
CK627_10845	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CK627_10855	COG1227	inorganic diphosphatase activity
CK627_10860	COG0497	DNA recombination
CK627_10865	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
CK627_10870	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
CK627_10875	COG0443	Heat shock 70 kDa protein
CK627_10880	COG0484	heat shock protein binding
CK627_10910	COG1285	pathogenesis
CK627_10925	COG0640	Transcriptional regulator
CK627_10955	COG0095	Lipoate-protein ligase
CK627_10970	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CK627_10975	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CK627_11000	COG0708	Exodeoxyribonuclease III
CK627_11020	COG2211	Major facilitator Superfamily
CK627_11060	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
CK627_11065	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
CK627_11070	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
CK627_11075	COG1845	cytochrome c oxidase, subunit III
CK627_11080	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
CK627_11085	COG0109	protoheme IX farnesyltransferase activity
CK627_11090	COG2814	Major facilitator Superfamily
CK627_11105	COG2175	clavaminate synthase activity
CK627_11110	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CK627_11115	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
CK627_11120	COG4521	taurine ABC transporter
CK627_11130	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
CK627_11180	COG0159	tryptophan synthase activity
CK627_11185	COG0133	tryptophan synthase activity
CK627_11190	COG0134	indole-3-glycerol-phosphate synthase activity
CK627_11190	COG0135	phosphoribosylanthranilate isomerase activity
CK627_11195	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
CK627_11200	COG0512	Glutamine amidotransferase of anthranilate synthase
CK627_11200	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
CK627_11205	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
CK627_11215	COG0009	L-threonylcarbamoyladenylate synthase
CK627_11225	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
CK627_11235	COG1946	Acyl-CoA thioesterase
CK627_11250	COG1309	transcriptional regulator
CK627_11255	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CK627_11260	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CK627_11265	COG1538	Outer membrane efflux protein
CK627_11275	COG1091	dTDP-4-dehydrorhamnose reductase activity
CK627_11280	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
CK627_11295	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CK627_11300	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
CK627_11305	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
CK627_11335	COG1051	belongs to the nudix hydrolase family
CK627_11350	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CK627_11365	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
CK627_11385	COG0438	transferase activity, transferring glycosyl groups
CK627_11390	COG1215	transferase activity, transferring glycosyl groups
CK627_11395	COG1216	Glycosyl transferase, family 2
CK627_11400	COG1596	polysaccharide export
CK627_11405	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CK627_11430	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CK627_11440	COG3132	Protein of unknown function, DUF480
CK627_11480	COG1278	Cold shock
CK627_11510	COG0697	spore germination
CK627_11515	COG1349	DNA-binding transcription factor activity
CK627_11525	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
CK627_11530	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
CK627_11545	COG1187	pseudouridine synthase activity
CK627_11555	COG4166	transmembrane transport
CK627_11560	COG0622	Phosphoesterase
CK627_11575	COG1261	Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly
CK627_11580	COG0784	Response regulator, receiver
CK627_11580	COG0835	chemotaxis
CK627_11585	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
CK627_11590	COG1815	bacterial-type flagellum-dependent cell motility
CK627_11595	COG1558	bacterial-type flagellum-dependent cell motility
CK627_11610	COG4787	bacterial-type flagellum-dependent cell motility
CK627_11615	COG4786	Flagellar basal body rod
CK627_11620	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
CK627_11625	COG1706	bacterial-type flagellum-dependent cell motility
CK627_11630	COG1705	Flagellar rod assembly protein muramidase FlgJ
CK627_11630	COG3951	Flagellar rod assembly protein muramidase FlgJ
CK627_11635	COG1256	bacterial-type flagellum assembly
CK627_11645	COG2239	Acts as a magnesium transporter
CK627_11650	COG0248	Ppx GppA phosphatase
CK627_11655	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
CK627_11660	COG2716	regulation of RNA biosynthetic process
CK627_11670	COG2204	response regulator
CK627_11675	COG3852	Histidine kinase
CK627_11680	COG2204	response regulator
CK627_11685	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
CK627_11690	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
CK627_11695	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
CK627_11700	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
CK627_11720	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
CK627_11735	COG0590	tRNA wobble adenosine to inosine editing
CK627_11740	COG0573	inorganic phosphate transmembrane transporter activity
CK627_11745	COG0581	inorganic phosphate transmembrane transporter activity
CK627_11755	COG0704	Plays a role in the regulation of phosphate uptake
CK627_11760	COG1253	flavin adenine dinucleotide binding
CK627_11775	COG0531	amino acid
CK627_11800	COG0765	amino acid transport
CK627_11805	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CK627_11810	COG2271	Major facilitator Superfamily
CK627_11825	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CK627_11855	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
CK627_11860	COG0477	Major facilitator Superfamily
CK627_11875	COG1199	ATP-dependent helicase activity
CK627_11880	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
CK627_11890	COG1448	Aminotransferase
CK627_11895	COG0433	COG0433 Predicted ATPase
CK627_11910	COG0658	competence protein
CK627_11910	COG2333	competence protein COMEC
CK627_11920	COG1663	tetraacyldisaccharide 4'-kinase activity
CK627_11925	COG2835	tetraacyldisaccharide 4'-kinase activity
CK627_11930	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
CK627_11935	COG2197	response regulator
CK627_11940	COG0322	excinuclease ABC activity
CK627_12000	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
CK627_12005	COG0437	4 iron, 4 sulfur cluster binding
CK627_12010	COG3301	Polysulphide reductase, NrfD
CK627_12015	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CK627_12025	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
CK627_12060	COG2203	Gaf domain
CK627_12060	COG2199	diguanylate cyclase activity
CK627_12090	COG2119	membrane
CK627_12095	COG0023	Translation Initiation Factor
CK627_12120	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
CK627_12135	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CK627_12135	COG2205	protein histidine kinase activity
CK627_12140	COG4139	cobalamin transport
CK627_12145	COG4138	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system
CK627_12150	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
CK627_12155	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
CK627_12160	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CK627_12165	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
CK627_12170	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
CK627_12180	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
CK627_12185	COG0505	Belongs to the CarA family
CK627_12190	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
CK627_12195	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CK627_12210	COG2814	Major facilitator Superfamily
CK627_12260	COG0513	Belongs to the DEAD box helicase family
CK627_12270	COG4104	PAAR repeat-containing protein
CK627_12285	COG0789	Transcriptional regulator
CK627_12300	COG0493	'glutamate synthase
CK627_12305	COG0067	glutamate synthase
CK627_12305	COG0069	glutamate synthase activity
CK627_12305	COG0070	glutamate synthase
CK627_12310	COG1242	4 iron, 4 sulfur cluster binding
CK627_12365	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
CK627_12370	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CK627_12370	COG0574	Belongs to the PEP-utilizing enzyme family
CK627_12410	COG1464	Belongs to the NlpA lipoprotein family
CK627_12415	COG0671	phosphoesterase, PA-phosphatase related
CK627_12420	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CK627_12425	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
CK627_12435	COG0101	tRNA pseudouridine synthase activity
CK627_12440	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
CK627_12445	COG0285	dihydrofolate synthase activity
CK627_12450	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
CK627_12455	COG2920	part of a sulfur-relay system
CK627_12460	COG1289	transmembrane transporter activity
CK627_12465	COG0670	Belongs to the BI1 family
CK627_12485	COG2194	sulfuric ester hydrolase activity
CK627_12490	COG0392	lysyltransferase activity
CK627_12490	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
CK627_12500	COG0840	transmembrane signaling receptor activity
CK627_12505	COG5001	Diguanylate cyclase
CK627_12510	COG0564	pseudouridine synthase activity
CK627_12525	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
CK627_12535	COG0625	glutathione transferase activity
CK627_12545	COG0367	asparagine synthase
CK627_12555	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
CK627_12555	COG4651	solute:proton antiporter activity
CK627_12560	COG0647	UMP catabolic process
CK627_12565	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
CK627_12570	COG1902	pentaerythritol trinitrate reductase activity
CK627_12575	COG1253	flavin adenine dinucleotide binding
CK627_12585	COG0247	lactate metabolic process
CK627_12585	COG0277	FAD linked oxidase domain protein
CK627_12595	COG2050	protein possibly involved in aromatic compounds catabolism
CK627_12605	COG2056	Na+-H+ antiporter family
CK627_12610	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CK627_12620	COG2885	chlorophyll binding
CK627_12625	COG0346	lactoylglutathione lyase activity
CK627_12630	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
CK627_12640	COG4659	FMN binding
CK627_12645	COG4658	electron transport chain
CK627_12655	COG2878	Part of a membrane complex involved in electron transport
CK627_12660	COG4657	Part of a membrane complex involved in electron transport
CK627_12665	COG0697	spore germination
CK627_12680	COG2932	Transcriptional regulator
CK627_12810	COG0640	Transcriptional regulator
CK627_12820	COG4373	Mu-like prophage FluMu protein gp28
CK627_12825	COG4383	Mu-like prophage protein gp29
CK627_12845	COG4388	Caudovirus prohead serine protease
CK627_12850	COG4397	Mu-like prophage major head subunit gpT
CK627_12915	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
CK627_12920	COG1288	antiporter activity
CK627_12925	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
CK627_12925	COG3264	Mechanosensitive ion channel
CK627_12930	COG0436	Aminotransferase
CK627_12940	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
CK627_12945	COG2027	D-alanyl-D-alanine carboxypeptidase
CK627_12950	COG1061	Type III restriction enzyme res subunit
CK627_12955	COG1566	PFAM secretion protein HlyD family protein
CK627_12965	COG1966	Carbon starvation protein
CK627_12970	COG3279	Response regulator of the LytR AlgR family
CK627_12975	COG3275	phosphorelay sensor kinase activity
CK627_12980	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
CK627_12980	COG2199	diguanylate cyclase activity
CK627_12985	COG1454	alcohol dehydrogenase
CK627_12985	COG1012	belongs to the aldehyde dehydrogenase family
CK627_12995	COG2095	MarC family integral membrane protein
CK627_13005	COG0601	transmembrane transport
CK627_13010	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CK627_13015	COG0444	Belongs to the ABC transporter superfamily
CK627_13025	COG0861	Integral membrane protein TerC family
CK627_13030	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
CK627_13040	COG1301	dicarboxylic acid transport
CK627_13055	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
CK627_13070	COG0537	adenosine 5'-monophosphoramidase activity
CK627_13105	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CK627_13110	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CK627_13125	COG2354	Protein conserved in bacteria
CK627_13135	COG1164	Oligoendopeptidase f
CK627_13140	COG2233	PERMEase
CK627_13155	COG1252	NADH dehydrogenase
CK627_13175	COG0393	Putative heavy-metal-binding
CK627_13185	COG1619	proteins homologs of microcin C7 resistance protein MccF
CK627_13190	COG1368	sulfuric ester hydrolase activity
CK627_13200	COG0527	aspartate kinase activity
CK627_13205	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
CK627_13205	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
CK627_13210	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CK627_13230	COG0596	Alpha beta hydrolase
CK627_13235	COG0583	DNA-binding transcription factor activity
CK627_13240	COG1620	l-lactate permease
CK627_13250	COG1139	Iron-sulfur cluster binding protein
CK627_13280	COG1136	(ABC) transporter
CK627_13300	COG2814	Major facilitator Superfamily
CK627_13320	COG0672	)-iron permease
CK627_13360	COG0659	secondary active sulfate transmembrane transporter activity
CK627_13375	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
CK627_13380	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
CK627_13385	COG0437	4 iron, 4 sulfur cluster binding
CK627_13390	COG5557	Pfam Polysulphide reductase, NrfD
CK627_13395	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
CK627_13400	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
CK627_13405	COG1773	rubredoxin
CK627_13415	COG0601	transmembrane transport
CK627_13420	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CK627_13425	COG0444	Belongs to the ABC transporter superfamily
CK627_13430	COG1124	(ABC) transporter
CK627_13435	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
CK627_13440	COG0375	protein maturation
CK627_13445	COG0309	Hydrogenase expression formation protein (HypE)
CK627_13455	COG0298	carbon dioxide binding
CK627_13460	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
CK627_13470	COG1921	L-seryl-tRNASec selenium transferase activity
CK627_13475	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
CK627_13485	COG3260	NADH ubiquinone oxidoreductase 20
CK627_13490	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CK627_13495	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
CK627_13495	COG3261	NADH dehydrogenase
CK627_13500	COG0650	Formate hydrogenlyase subunit 4
CK627_13505	COG0651	ATP synthesis coupled electron transport
CK627_13510	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
CK627_13515	COG3158	transport of potassium into the cell
CK627_13525	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
CK627_13550	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
CK627_13555	COG0326	Molecular chaperone. Has ATPase activity
CK627_13565	COG0563	adenylate kinase activity
CK627_13570	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
CK627_13580	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CK627_13595	COG3300	MHYT domain
CK627_13595	COG5001	Diguanylate cyclase
CK627_13600	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
CK627_13620	COG1021	2,3-dihydroxybenzoate-AMP ligase
CK627_13625	COG1535	isochorismatase
CK627_13625	COG3433	isochorismatase activity
CK627_13630	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CK627_13635	COG1028	Short-chain dehydrogenase reductase Sdr
CK627_13645	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CK627_13650	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CK627_13655	COG2977	Belongs to the P-Pant transferase superfamily
CK627_13660	COG1120	ATPase activity
CK627_13665	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CK627_13670	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CK627_13675	COG4771	TonB-dependent receptor
CK627_13695	COG0598	Magnesium transport protein CorA
CK627_13715	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
CK627_13720	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
CK627_13725	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
CK627_13740	COG1570	exodeoxyribonuclease VII activity
CK627_13745	COG0697	spore germination
CK627_13765	COG3158	transport of potassium into the cell
CK627_13770	COG0516	GMP reductase activity
CK627_13770	COG0517	IMP dehydrogenase activity
CK627_13775	COG0519	Catalyzes the synthesis of GMP from XMP
CK627_13775	COG0518	GMP synthase (glutamine-hydrolyzing) activity
CK627_13780	COG0582	viral genome integration into host DNA
CK627_13855	COG2062	phosphohistidine phosphatase, SixA
CK627_13870	COG4166	transmembrane transport
CK627_13875	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
CK627_13880	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
CK627_13890	COG4591	ABC-type transport system involved in lipoprotein release permease component
CK627_13895	COG1136	(ABC) transporter
CK627_13900	COG4591	ABC-type transport system involved in lipoprotein release permease component
CK627_13905	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
CK627_13920	COG0544	peptidyl-prolyl cis-trans isomerase activity
CK627_13925	COG0740	serine-type endopeptidase activity
CK627_13930	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
CK627_13935	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
CK627_13940	COG0776	regulation of translation
CK627_13945	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CK627_13950	COG0488	(ABC) transporter
CK627_13955	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CK627_13960	COG3162	membrane
CK627_13975	COG1024	Enoyl-CoA hydratase
CK627_13980	COG1115	amino acid carrier protein
CK627_13995	COG1584	GPR1 FUN34 yaaH family protein
CK627_14030	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
CK627_14035	COG1960	acyl-CoA dehydrogenase activity
CK627_14045	COG1960	acyl-CoA dehydrogenase activity
CK627_14050	COG1024	Enoyl-CoA hydratase
CK627_14055	COG1024	Enoyl-CoA hydratase
CK627_14065	COG1028	Short-chain dehydrogenase reductase Sdr
CK627_14075	COG0730	response to heat
CK627_14090	COG1073	alpha beta
CK627_14095	COG1506	peptidase
CK627_14095	COG0823	Involved in the tonB-independent uptake of proteins
CK627_14100	COG0702	epimerase
CK627_14105	COG0583	DNA-binding transcription factor activity
CK627_14110	COG0667	Aldo Keto reductase
CK627_14160	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
CK627_14170	COG0438	transferase activity, transferring glycosyl groups
CK627_14235	COG0438	transferase activity, transferring glycosyl groups
CK627_14240	COG0583	DNA-binding transcription factor activity
CK627_14245	COG2723	6-phospho-beta-galactosidase activity
CK627_14250	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
CK627_14260	COG0583	DNA-binding transcription factor activity
CK627_14265	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
CK627_14270	COG0673	inositol 2-dehydrogenase activity
CK627_14275	COG0583	DNA-binding transcription factor activity
CK627_14285	COG1560	Kdo2-lipid A biosynthetic process
CK627_14290	COG1560	Kdo2-lipid A biosynthetic process
CK627_14305	COG2203	Gaf domain
CK627_14305	COG2199	diguanylate cyclase activity
CK627_14315	COG0417	DNA replication proofreading
CK627_14350	COG0534	Mate efflux family protein
CK627_14360	COG0307	riboflavin synthase, alpha
CK627_14370	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CK627_14375	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
CK627_14380	COG0697	spore germination
CK627_14385	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
CK627_14425	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CK627_14435	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
CK627_14440	COG2894	cell division
CK627_14445	COG0850	regulation of cytokinetic process
CK627_14450	COG3100	YcgL domain-containing protein
CK627_14455	COG2951	lytic endotransglycosylase activity
CK627_14460	COG1760	l-serine dehydratase
CK627_14470	COG1760	l-serine dehydratase
CK627_14475	COG3123	guanosine phosphorylase activity
CK627_14495	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
CK627_14500	COG2067	long-chain fatty acid transport protein
CK627_14515	COG1595	DNA-templated transcription, initiation
CK627_14545	COG0714	Associated with various cellular activities
CK627_14550	COG0183	Belongs to the thiolase family
CK627_14555	COG1250	3-hydroxyacyl-CoA dehydrogenase
CK627_14555	COG1024	Enoyl-CoA hydratase
CK627_14565	COG4681	YaeQ
CK627_14585	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
CK627_14590	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CK627_14595	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CK627_14605	COG0549	Belongs to the carbamate kinase family
CK627_14610	COG0697	spore germination
CK627_14615	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
CK627_14615	COG3608	succinylglutamate desuccinylase aspartoacylase
CK627_14620	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
CK627_14625	COG2068	MobA-Related Protein
CK627_14630	COG0493	'glutamate synthase
CK627_14630	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
CK627_14635	COG0402	S-adenosylhomocysteine deaminase activity
CK627_14640	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
CK627_14645	COG2080	2 iron, 2 sulfur cluster binding
CK627_14645	COG1529	Aldehyde oxidase and xanthine dehydrogenase
CK627_14650	COG2233	PERMEase
CK627_14655	COG0402	S-adenosylhomocysteine deaminase activity
CK627_14660	COG2252	PERMEase
CK627_14665	COG1529	Aldehyde oxidase and xanthine dehydrogenase
CK627_14670	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
CK627_14675	COG2080	2 iron, 2 sulfur cluster binding
CK627_14685	COG3134	Outer membrane lipoprotein
CK627_14695	COG1288	antiporter activity
CK627_14700	COG0318	PFAM AMP-dependent synthetase and ligase
CK627_14705	COG2378	regulation of single-species biofilm formation
CK627_14715	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
CK627_14715	COG0140	phosphoribosyl-ATP diphosphatase activity
CK627_14720	COG0107	imidazoleglycerol-phosphate synthase activity
CK627_14735	COG3437	response regulator, receiver
CK627_14740	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
CK627_14745	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
CK627_14750	COG0131	Imidazoleglycerol-phosphate dehydratase
CK627_14750	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
CK627_14755	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CK627_14760	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
CK627_14765	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
CK627_14775	COG1199	ATP-dependent helicase activity
CK627_14780	COG1214	PFAM Peptidase M22, glycoprotease
CK627_14790	COG2267	carboxylic ester hydrolase activity
CK627_14795	COG0318	PFAM AMP-dependent synthetase and ligase
CK627_14815	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CK627_14820	COG2832	Protein of unknown function (DUF454)
CK627_14825	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
CK627_14835	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
CK627_14840	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
CK627_14865	COG1643	Atp-dependent helicase
CK627_14875	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
CK627_14885	COG3437	response regulator, receiver
CK627_14890	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CK627_14895	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
CK627_14900	COG0709	Synthesizes selenophosphate from selenide and ATP
CK627_14915	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
CK627_14920	COG0840	transmembrane signaling receptor activity
CK627_14925	COG1254	Belongs to the acylphosphatase family
CK627_14930	COG0625	glutathione transferase activity
CK627_14935	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CK627_14935	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CK627_14940	COG0489	protein tyrosine kinase activity
CK627_14945	COG0572	uridine kinase
CK627_14950	COG0717	Belongs to the dCTP deaminase family
CK627_14955	COG0306	phosphate transporter
CK627_14960	COG1530	ribonuclease E activity
CK627_14970	COG0546	phosphoglycolate phosphatase activity
CK627_14975	COG0424	maF-like protein
CK627_14980	COG2814	Major facilitator Superfamily
CK627_14995	COG1399	metal-binding, possibly nucleic acid-binding protein
CK627_15000	COG0333	Belongs to the bacterial ribosomal protein bL32 family
CK627_15005	COG0416	fatty acid biosynthetic process
CK627_15010	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CK627_15020	COG1028	Short-chain dehydrogenase reductase Sdr
CK627_15025	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CK627_15030	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CK627_15035	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CK627_15040	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
CK627_15045	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
CK627_15050	COG0470	DNA polymerase III
CK627_15055	COG0084	hydrolase, TatD family'
CK627_15070	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
CK627_15070	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
CK627_15075	COG3008	intermembrane lipid transfer
CK627_15080	COG2995	paraquat-inducible protein a
CK627_15090	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
CK627_15095	COG0372	Belongs to the citrate synthase family
CK627_15140	COG4221	oxidoreductase activity
CK627_15150	COG3141	response to X-ray
CK627_15230	COG4128	Pfam Zonular occludens toxin
CK627_15270	COG1067	ATP-dependent peptidase activity
CK627_15275	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
CK627_15290	COG0488	(ABC) transporter
CK627_15300	COG0116	Belongs to the methyltransferase superfamily
CK627_15300	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
CK627_15310	COG0167	dihydroorotate dehydrogenase activity
CK627_15315	COG2902	Dehydrogenase
CK627_15325	COG0308	aminopeptidase N
CK627_15335	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
CK627_15340	COG1956	GAF domain-containing protein
CK627_15350	COG3278	Belongs to the heme-copper respiratory oxidase family
CK627_15365	COG2010	Cytochrome c
CK627_15390	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CK627_15395	COG0589	response to stress
CK627_15400	COG0037	tRNA processing
CK627_15420	COG1869	D-ribose catabolic process
CK627_15425	COG1129	ABC transporter
CK627_15430	COG1172	Belongs to the binding-protein-dependent transport system permease family
CK627_15435	COG1879	ABC-type sugar transport system periplasmic component
CK627_15440	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CK627_15445	COG1609	Transcriptional regulator
CK627_15450	COG5001	Diguanylate cyclase
CK627_15450	COG3300	MHYT domain
CK627_15460	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
CK627_15475	COG2205	protein histidine kinase activity
CK627_15475	COG0784	Response regulator, receiver
CK627_15480	COG0776	regulation of translation
CK627_15485	COG0072	phenylalanine-tRNA ligase activity
CK627_15485	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CK627_15490	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
CK627_15495	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
CK627_15500	COG0291	Belongs to the bacterial ribosomal protein bL35 family
CK627_15505	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
CK627_15510	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
CK627_15530	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
CK627_15540	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CK627_15545	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CK627_15550	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CK627_15555	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
CK627_15560	COG3313	Fe-S protein
CK627_15565	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CK627_15565	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CK627_15565	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
CK627_15570	COG1105	Belongs to the carbohydrate kinase PfkB family
CK627_15575	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
CK627_15575	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CK627_15580	COG1609	Transcriptional regulator
CK627_15585	COG0814	amino acid
CK627_15600	COG0513	Belongs to the DEAD box helicase family
CK627_15610	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
CK627_15615	COG2890	protein-(glutamine-N5) methyltransferase activity
CK627_15620	COG2840	Smr protein MutS2
CK627_15630	COG3706	GGDEF domain
CK627_15635	COG0406	alpha-ribazole phosphatase activity
CK627_15660	COG2824	Alkylphosphonate utilization operon protein PhnA
CK627_15680	COG0384	phenazine biosynthesis protein PhzF
CK627_15705	COG0242	peptide deformylase activity
CK627_15745	COG0251	oxidation-reduction process
CK627_15750	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
CK627_15755	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
CK627_15760	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
CK627_15770	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
CK627_15775	COG1434	Gram-negative-bacterium-type cell wall biogenesis
CK627_15785	COG0205	6-phosphofructokinase activity
CK627_15790	COG1473	amidohydrolase
CK627_15795	COG1011	Hydrolase
CK627_15800	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
CK627_15855	COG3593	DNA synthesis involved in DNA repair
CK627_15870	COG0583	DNA-binding transcription factor activity
CK627_15875	COG0730	response to heat
CK627_15890	COG1181	Belongs to the D-alanine--D-alanine ligase family
CK627_15900	COG0386	Belongs to the glutathione peroxidase family
CK627_15905	COG0513	Belongs to the DEAD box helicase family
CK627_15910	COG0456	acetyltransferase
CK627_15945	COG2329	Antibiotic biosynthesis monooxygenase
CK627_15950	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
CK627_15980	COG2501	S4 domain
CK627_15995	COG1132	(ABC) transporter
CK627_16005	COG1132	(ABC) transporter
CK627_16015	COG3118	belongs to the thioredoxin family
CK627_16020	COG0471	metal ion transport
CK627_16025	COG0058	SHG alpha-glucan phosphorylase activity
CK627_16060	COG0814	amino acid
CK627_16065	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
CK627_16070	COG0514	ATP-dependent DNA helicase (RecQ)
CK627_16075	COG2766	serine protein kinase
CK627_16080	COG2718	Belongs to the UPF0229 family
CK627_16085	COG2719	SpoVR family
CK627_16090	COG2186	Transcriptional regulator
CK627_16095	COG3067	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
CK627_16100	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
CK627_16105	COG0586	Pfam SNARE associated Golgi protein
CK627_16115	COG0556	nucleotide-excision repair
CK627_16130	COG0569	domain protein
CK627_16130	COG2985	domain, Protein
CK627_16135	COG0741	lytic transglycosylase activity
CK627_16135	COG0739	heme binding
CK627_16135	COG1196	nuclear chromosome segregation
CK627_16140	COG3181	Tripartite tricarboxylate transporter family receptor
CK627_16155	COG4565	transcriptional regulatory protein
CK627_16160	COG3290	protein histidine kinase activity
CK627_16165	COG1846	Transcriptional regulator
CK627_16165	COG1940	carbohydrate kinase activity
CK627_16170	COG0840	transmembrane signaling receptor activity
CK627_16175	COG3012	SEC-C Motif Domain Protein
CK627_16180	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
CK627_16185	COG3075	Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses fumarate or nitrate as electron acceptor
CK627_16190	COG0247	lactate metabolic process
CK627_16200	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
CK627_16205	COG0437	4 iron, 4 sulfur cluster binding
CK627_16210	COG3301	Polysulphide reductase, NrfD
CK627_16215	COG1138	Cytochrome C-type biogenesis protein
CK627_16220	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CK627_16225	COG3088	subunit of a heme lyase
CK627_16225	COG4235	cytochrome complex assembly
CK627_16240	COG3033	Beta-eliminating lyase
CK627_16250	COG3046	protein related to deoxyribodipyrimidine photolyase
CK627_16255	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CK627_16270	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
CK627_16275	COG0583	DNA-binding transcription factor activity
CK627_16285	COG4774	siderophore transport
CK627_16290	COG4977	sequence-specific DNA binding
CK627_16300	COG0583	DNA-binding transcription factor activity
CK627_16305	COG2910	NAD(P)H-binding
CK627_16315	COG0626	cystathionine gamma-synthase activity
CK627_16320	COG0612	Peptidase, M16
CK627_16325	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
CK627_16330	COG2076	Multidrug Resistance protein
CK627_16335	COG1944	ATP diphosphatase activity
CK627_16340	COG2116	formate transmembrane transporter activity
CK627_16345	COG1882	Formate acetyltransferase
CK627_16350	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CK627_16360	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
CK627_16370	COG1840	ABC-type Fe3 transport system, periplasmic component
CK627_16375	COG3842	ATPase activity
CK627_16385	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CK627_16390	COG2983	Belongs to the UPF0260 family
CK627_16395	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
CK627_16400	COG0045	succinate-CoA ligase (ADP-forming) activity
CK627_16405	COG0508	dehydrogenase complex catalyzes the overall conversion of
CK627_16410	COG0567	Dehydrogenase, E1 component
CK627_16425	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
CK627_16430	COG2009	succinate dehydrogenase
CK627_16450	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CK627_16455	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
CK627_16455	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CK627_16465	COG3069	C4-dicarboxylate transmembrane transporter activity
CK627_16480	COG1451	nucleotide metabolic process
CK627_16495	COG0254	rRNA binding
CK627_16500	COG0257	Belongs to the bacterial ribosomal protein bL36 family
CK627_16510	COG0583	DNA-binding transcription factor activity
CK627_16515	COG2925	Exonuclease
CK627_16525	COG3345	alpha-galactosidase
CK627_16530	COG1380	Effector of murein hydrolase LrgA
CK627_16535	COG1346	cytolysis
CK627_16540	COG0295	cytidine deaminase activity
CK627_16545	COG1022	Amp-dependent synthetase and ligase
CK627_16560	COG0861	Integral membrane protein TerC family
CK627_16565	COG2885	chlorophyll binding
CK627_16590	COG2154	pterin-4-alpha-carbinolamine dehydratase
CK627_16600	COG3768	UPF0283 membrane protein
CK627_16605	COG3106	COG3106 Predicted ATPase
CK627_16620	COG1842	Phage shock protein A
CK627_16625	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
CK627_16635	COG4168	peptide transport system, permease
CK627_16640	COG4171	peptide transport system, permease
CK627_16650	COG4172	Belongs to the ABC transporter superfamily
CK627_16660	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
CK627_16665	COG1286	toxin biosynthetic process
CK627_16670	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
CK627_16675	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
CK627_16680	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
CK627_16685	COG1674	ftsk spoiiie
CK627_16685	COG0531	amino acid
CK627_16695	COG0492	ferredoxin-NADP+ reductase activity
CK627_16700	COG3706	GGDEF domain
CK627_16705	COG3134	Outer membrane lipoprotein
CK627_16710	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
CK627_16715	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
CK627_16720	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
CK627_16725	COG0542	response to heat
CK627_16730	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
CK627_16735	COG1278	Cold shock
CK627_16740	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
CK627_16765	COG3501	Rhs element vgr protein
CK627_16870	COG3501	Rhs element vgr protein
CK627_16900	COG1435	thymidine kinase activity
CK627_16905	COG1757	Na H antiporter
CK627_16910	COG2916	Histone family protein nucleoid-structuring protein H-NS
CK627_16915	COG2096	Adenosyltransferase
CK627_16920	COG3530	Putative quorum-sensing-regulated virulence factor
CK627_16925	COG0602	queuosine metabolic process
CK627_16930	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
CK627_16950	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
CK627_16960	COG0776	regulation of translation
CK627_16965	COG0539	negative regulation of cytoplasmic translation
CK627_16970	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
CK627_16975	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CK627_16985	COG0583	DNA-binding transcription factor activity
CK627_17005	COG0778	Nitroreductase
CK627_17010	COG3300	MHYT domain
CK627_17010	COG5001	Diguanylate cyclase
CK627_17020	COG0583	DNA-binding transcription factor activity
CK627_17025	COG3437	response regulator, receiver
CK627_17050	COG4989	oxidoreductase activity
CK627_17055	COG0724	RNA recognition motif
CK627_17075	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
CK627_17095	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
CK627_17100	COG1360	Flagellar Motor Protein
CK627_17105	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CK627_17110	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CK627_17115	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CK627_17115	COG0649	NAD binding
CK627_17130	COG1034	ATP synthesis coupled electron transport
CK627_17135	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
CK627_17140	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CK627_17145	COG0839	Belongs to the complex I subunit 6 family
CK627_17150	COG0713	ATP synthesis coupled electron transport
CK627_17160	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CK627_17165	COG1007	ATP synthesis coupled electron transport
CK627_17180	COG2199	diguanylate cyclase activity
CK627_17180	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
CK627_17185	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CK627_17185	COG0047	phosphoribosylformylglycinamidine synthase activity
CK627_17190	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
CK627_17200	COG1645	bacterial-type flagellum-dependent swarming motility
CK627_17205	COG1160	GTP binding
CK627_17210	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CK627_17215	COG2976	Protein conserved in bacteria
CK627_17220	COG0124	histidyl-tRNA synthetase
CK627_17225	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
CK627_17240	COG0820	rRNA (adenine-C2-)-methyltransferase activity
CK627_17245	COG0105	UTP biosynthetic process
CK627_17250	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
CK627_17260	COG0633	Ferredoxin
CK627_17265	COG0443	Heat shock 70 kDa protein
CK627_17270	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
CK627_17280	COG0822	iron-sulfur transferase activity
CK627_17285	COG1104	cysteine desulfurase activity
CK627_17330	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CK627_17335	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CK627_17340	COG1862	Preprotein translocase
CK627_17345	COG0343	queuine tRNA-ribosyltransferase activity
CK627_17350	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
CK627_17355	COG0517	IMP dehydrogenase activity
CK627_17360	COG0450	alkyl hydroperoxide reductase
CK627_17365	COG3634	alkyl hydroperoxide reductase activity
CK627_17375	COG3852	Histidine kinase
CK627_17395	COG0641	radical SAM
CK627_17400	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
CK627_17400	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
CK627_17405	COG0509	glycine decarboxylation via glycine cleavage system
CK627_17410	COG0404	The glycine cleavage system catalyzes the degradation of glycine
CK627_17415	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CK627_17420	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CK627_17440	COG2814	Major facilitator Superfamily
CK627_17445	COG0625	glutathione transferase activity
CK627_17455	COG0483	inositol monophosphate 1-phosphatase activity
CK627_17475	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
CK627_17490	COG1086	Polysaccharide biosynthesis protein
CK627_17520	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
CK627_17540	COG0301	tRNA thio-modification
CK627_17540	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CK627_17550	COG4953	penicillin-binding protein 1C
CK627_17555	COG2373	Large extracellular alpha-helical protein
CK627_17560	COG0446	pyridine nucleotide-disulphide oxidoreductase
CK627_17570	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
CK627_17585	COG4215	(ABC) transporter
CK627_17590	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CK627_17600	COG2431	L-lysine efflux transmembrane transporter activity
CK627_17605	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
CK627_17625	COG1393	Belongs to the ArsC family
CK627_17635	COG4783	chaperone-mediated protein folding
CK627_17640	COG0425	Belongs to the sulfur carrier protein TusA family
CK627_17665	COG3842	ATPase activity
CK627_17675	COG1175	transmembrane transport
CK627_17685	COG3081	Nucleoid-associated protein
CK627_17690	COG3082	Protein of unknown function (DUF1414)
CK627_17695	COG3083	sulfuric ester hydrolase activity
CK627_17700	COG4771	TonB-dependent receptor
CK627_17705	COG1770	oligopeptidase
CK627_17725	COG4574	serine-type endopeptidase inhibitor activity
CK627_17730	COG3085	chromosome segregation
CK627_17735	COG0583	DNA-binding transcription factor activity
CK627_17740	COG0287	Prephenate dehydrogenase
CK627_17740	COG1605	Chorismate mutase
CK627_17745	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
CK627_17750	COG0584	glycerophosphoryl diester phosphodiesterase
CK627_17760	COG1349	DNA-binding transcription factor activity
CK627_17765	COG2271	Major facilitator Superfamily
CK627_17770	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
CK627_17775	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
CK627_17780	COG0840	transmembrane signaling receptor activity
CK627_17790	COG0583	DNA-binding transcription factor activity
CK627_17810	COG0656	L-ascorbic acid biosynthetic process
CK627_17815	COG2814	Major facilitator Superfamily
CK627_17830	COG3220	belongs to the UPF0276 family
CK627_17850	COG1294	oxidase, subunit
CK627_17860	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CK627_17870	COG2979	Protein of unknown function (DUF533)
CK627_17900	COG2271	Major facilitator Superfamily
CK627_17905	COG0583	DNA-binding transcription factor activity
CK627_17915	COG2807	transmembrane transport
CK627_17925	COG1187	pseudouridine synthase activity
CK627_17940	COG0346	lactoylglutathione lyase activity
CK627_17950	COG1403	HNH endonuclease
CK627_17960	COG2964	Protein conserved in bacteria
CK627_17965	COG3681	Belongs to the UPF0597 family
CK627_17975	COG0814	amino acid
CK627_17995	COG0583	DNA-binding transcription factor activity
CK627_18000	COG2015	COG2015, Alkyl sulfatase and related hydrolases
CK627_18010	COG1166	arginine decarboxylase activity
CK627_18025	COG2195	Cleaves the N-terminal amino acid of tripeptides
CK627_18055	COG0583	DNA-binding transcription factor activity
CK627_18065	COG2759	Belongs to the formate--tetrahydrofolate ligase family
CK627_18070	COG0840	transmembrane signaling receptor activity
CK627_18075	COG0302	gtp cyclohydrolase
CK627_18085	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
CK627_18090	COG2267	carboxylic ester hydrolase activity
CK627_18095	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
CK627_18110	COG0314	molybdopterin synthase activity
CK627_18115	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
CK627_18120	COG0315	cyclic pyranopterin monophosphate synthase activity
CK627_18125	COG0521	Mo-molybdopterin cofactor biosynthetic process
CK627_18130	COG3005	denitrification pathway
CK627_18140	COG0348	domain, Protein
CK627_18145	COG0437	4 iron, 4 sulfur cluster binding
CK627_18150	COG0243	molybdopterin cofactor binding
CK627_18160	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
CK627_18160	COG1149	4fe-4S ferredoxin, iron-sulfur binding domain protein
CK627_18165	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
CK627_18170	COG3850	Histidine kinase
CK627_18175	COG2197	response regulator
CK627_18185	COG0784	Response regulator, receiver
CK627_18185	COG2205	protein histidine kinase activity
CK627_18205	COG0121	glutamine amidotransferase
CK627_18210	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
CK627_18215	COG1960	acyl-CoA dehydrogenase activity
CK627_18220	COG0784	Response regulator, receiver
CK627_18220	COG3437	response regulator, receiver
CK627_18230	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CK627_18235	COG0328	RNA-DNA hybrid ribonuclease activity
CK627_18240	COG2226	methyltransferase
CK627_18245	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CK627_18250	COG1388	LysM domain
CK627_18250	COG0741	lytic transglycosylase activity
CK627_18255	COG3021	interspecies interaction between organisms
CK627_18265	COG1607	acyl-coa hydrolase
CK627_18280	COG0741	lytic transglycosylase activity
CK627_18290	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
CK627_18310	COG2911	Protein conserved in bacteria
CK627_18315	COG0729	surface antigen
CK627_18325	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CK627_18330	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CK627_18340	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CK627_18350	COG4134	Bacterial extracellular solute-binding protein
CK627_18360	COG4136	ATPase activity
CK627_18365	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
CK627_18370	COG2951	lytic endotransglycosylase activity
CK627_18385	COG1846	Transcriptional regulator
CK627_18395	COG0033	Phosphoglucomutase
CK627_18400	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
CK627_18405	COG0596	Alpha beta hydrolase
CK627_18420	COG0716	FMN binding
CK627_18430	COG0735	belongs to the Fur family
CK627_18435	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CK627_18445	COG2190	(PTS) system
CK627_18445	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CK627_18445	COG1263	PTS System
CK627_18450	COG0363	glucosamine-6-phosphate deaminase activity
CK627_18455	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
CK627_18460	COG1940	carbohydrate kinase activity
CK627_18460	COG1846	Transcriptional regulator
CK627_18465	COG2194	sulfuric ester hydrolase activity
CK627_18470	COG0217	transcriptional regulatory protein
CK627_18475	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
CK627_18485	COG1801	Protein of unknown function DUF72
CK627_18490	COG4106	trans-aconitate 2-methyltransferase activity
CK627_18495	COG0500	methyltransferase
CK627_18515	COG0450	alkyl hydroperoxide reductase
CK627_18520	COG0583	DNA-binding transcription factor activity
CK627_18530	COG0791	NLP P60 protein
CK627_18545	COG1309	transcriptional regulator
CK627_18585	COG0534	Mate efflux family protein
CK627_18595	COG2841	Protein conserved in bacteria
CK627_18600	COG2169	Transcriptional regulator
CK627_18600	COG1917	Cupin 2, conserved barrel domain protein
CK627_18605	COG2366	antibiotic biosynthetic process
CK627_18610	COG0674	pyruvate-flavodoxin oxidoreductase activity
CK627_18610	COG1013	pyruvate-flavodoxin oxidoreductase activity
CK627_18610	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
CK627_18610	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
CK627_18620	COG3217	Mosc domain protein beta barrel domain protein
CK627_18620	COG0633	Ferredoxin
CK627_18620	COG3217	Mosc domain protein beta barrel domain protein
CK627_18620	COG0633	Ferredoxin
CK627_18630	COG0501	Belongs to the peptidase M48B family
CK627_18635	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
CK627_18640	COG1073	alpha beta
CK627_18640	COG2226	methyltransferase
CK627_18645	COG0156	8-amino-7-oxononanoate synthase activity
CK627_18650	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
CK627_18670	COG0017	Asparaginyl-tRNA synthetase
CK627_18675	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
CK627_18690	COG3069	C4-dicarboxylate transmembrane transporter activity
CK627_18700	COG0583	DNA-binding transcription factor activity
CK627_18705	COG1393	Belongs to the ArsC family
CK627_18710	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CK627_18715	COG1876	peptidase activity
CK627_18725	COG3263	regulation of cellular component size
CK627_18745	COG1280	lysine exporter protein (LysE YggA)
CK627_18775	COG0564	pseudouridine synthase activity
CK627_18780	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
CK627_18785	COG1454	alcohol dehydrogenase
CK627_18790	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CK627_18795	COG0702	epimerase
CK627_18800	COG2914	Belongs to the UPF0125 (RnfH) family
CK627_18805	COG2867	negative regulation of translational initiation
CK627_18810	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
CK627_18905	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
CK627_18940	COG2814	Major facilitator Superfamily
CK627_18940	COG0477	Major facilitator Superfamily
CK627_18945	COG0457	Tetratricopeptide repeat
CK627_18950	COG1940	carbohydrate kinase activity
CK627_18955	COG0583	DNA-binding transcription factor activity
CK627_18960	COG3048	D-serine ammonia-lyase activity
CK627_18970	COG0538	isocitrate dehydrogenase activity
CK627_18975	COG2207	Transcriptional regulator
CK627_18995	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CK627_19005	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
CK627_19010	COG1263	PTS System
CK627_19010	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CK627_19015	COG1609	Transcriptional regulator
CK627_19020	COG0446	pyridine nucleotide-disulphide oxidoreductase
CK627_19020	COG1902	pentaerythritol trinitrate reductase activity
CK627_19025	COG0789	Transcriptional regulator
CK627_19035	COG0456	acetyltransferase
CK627_19050	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CK627_19050	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CK627_19050	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CK627_19060	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CK627_19070	COG1187	pseudouridine synthase activity
CK627_19080	COG0482	sulfurtransferase activity
CK627_19085	COG2915	High frequency lysogenization protein hflD homolog
CK627_19090	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
CK627_19095	COG2850	peptidyl-arginine hydroxylation
CK627_19105	COG3153	acetyltransferase
CK627_19115	COG0625	glutathione transferase activity
CK627_19120	COG0259	pyridoxamine-phosphate oxidase activity
CK627_19135	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CK627_19135	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
CK627_19140	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
CK627_19160	COG4235	cytochrome complex assembly
CK627_19160	COG3088	subunit of a heme lyase
CK627_19165	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CK627_19170	COG1138	Cytochrome C-type biogenesis protein
CK627_19175	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
CK627_19180	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CK627_19185	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CK627_19190	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CK627_19205	COG0835	chemotaxis
CK627_19215	COG1192	Involved in chromosome partitioning
CK627_19220	COG1360	Flagellar Motor Protein
CK627_19225	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
CK627_19235	COG2198	Histidine kinase
CK627_19235	COG0643	Histidine kinase
CK627_19240	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
CK627_19255	COG0455	bacterial-type flagellum organization
CK627_19265	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
CK627_19275	COG1684	flagellar biosynthetic protein fliR
CK627_19280	COG1987	bacterial-type flagellum assembly
CK627_19330	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
CK627_19340	COG1677	Flagellar hook-basal body complex protein FliE
CK627_19355	COG1393	Belongs to the ArsC family
CK627_19360	COG0798	PFAM Bile acid sodium symporter
CK627_19375	COG0640	Transcriptional regulator
CK627_19380	COG1342	Belongs to the UPF0251 family
CK627_19400	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CK627_19405	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
CK627_19405	COG1073	alpha beta
CK627_19405	COG3064	Membrane
CK627_19410	COG2994	toxin metabolic process
CK627_19420	COG2274	protein secretion by the type I secretion system
CK627_19430	COG2274	protein secretion by the type I secretion system
CK627_19435	COG0745	RESPONSE REGULATOR receiver
CK627_19450	COG1737	Transcriptional regulator
CK627_19455	COG0469	pyruvate kinase activity
CK627_19470	COG1960	acyl-CoA dehydrogenase activity
CK627_19480	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
CK627_19490	COG0243	molybdopterin cofactor binding
CK627_19495	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
CK627_19500	COG0583	DNA-binding transcription factor activity
CK627_19520	COG5002	protein histidine kinase activity
CK627_19525	COG0745	RESPONSE REGULATOR receiver
CK627_19530	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CK627_19535	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CK627_19555	COG1388	LysM domain
CK627_19555	COG1376	ErfK ybiS ycfS ynhG family protein
CK627_19570	COG3129	Specifically methylates the adenine in position 1618 of 23S rRNA
CK627_19575	COG0791	NLP P60 protein
CK627_19585	COG3118	belongs to the thioredoxin family
CK627_19595	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CK627_19600	COG0788	formyltetrahydrofolate deformylase activity
CK627_19610	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CK627_19630	COG0366	Alpha amylase catalytic
CK627_19635	COG0739	heme binding
CK627_19635	COG0741	lytic transglycosylase activity
CK627_19635	COG1196	nuclear chromosome segregation
CK627_19640	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
CK627_19645	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
CK627_19650	COG0673	inositol 2-dehydrogenase activity
CK627_19680	COG3152	Membrane
CK627_19700	COG1032	radical SAM domain protein
CK627_19710	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CK627_19715	COG1566	PFAM secretion protein HlyD family protein
CK627_19720	COG3706	GGDEF domain
CK627_19725	COG1752	Esterase of the alpha-beta hydrolase superfamily
CK627_19730	COG0733	neurotransmitter:sodium symporter activity
CK627_19760	COG0281	malic enzyme
CK627_19765	COG2207	Transcriptional regulator
CK627_19770	COG0534	Mate efflux family protein
CK627_19780	COG0745	RESPONSE REGULATOR receiver
CK627_19780	COG3706	GGDEF domain
CK627_19785	COG2233	PERMEase
CK627_19790	COG0095	Lipoate-protein ligase
CK627_19795	COG1115	amino acid carrier protein
CK627_19800	COG0019	diaminopimelate decarboxylase activity
CK627_19820	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
CK627_19830	COG1126	abc transporter atp-binding protein
CK627_19835	COG0765	amino acid transport
CK627_19840	COG4597	amino acid ABC transporter
CK627_19845	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CK627_19860	COG1131	(ABC) transporter
CK627_19865	COG0545	Peptidyl-prolyl cis-trans isomerase
CK627_19890	COG4783	chaperone-mediated protein folding
CK627_19900	COG5002	protein histidine kinase activity
CK627_19905	COG0745	RESPONSE REGULATOR receiver
CK627_19910	COG0346	lactoylglutathione lyase activity
CK627_19915	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CK627_19920	COG1960	acyl-CoA dehydrogenase activity
CK627_19925	COG3284	Transcriptional regulator
CK627_19930	COG1012	belongs to the aldehyde dehydrogenase family
CK627_19940	COG0697	spore germination
CK627_19945	COG4565	transcriptional regulatory protein
CK627_19950	COG3290	protein histidine kinase activity
CK627_19955	COG0281	malic enzyme
CK627_19970	COG1846	Transcriptional regulator
CK627_19975	COG1566	PFAM secretion protein HlyD family protein
CK627_20005	COG0602	queuosine metabolic process
CK627_20010	COG1328	CTP reductase activity
CK627_20020	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
CK627_20025	COG3115	cell septum assembly
CK627_20030	COG1196	nuclear chromosome segregation
CK627_20040	COG2860	membrane
CK627_20050	COG3108	Peptidase M15
CK627_20055	COG2989	Protein conserved in bacteria
CK627_20070	COG0463	Glycosyl transferase, family 2
CK627_20085	COG0366	Alpha amylase catalytic
CK627_20120	COG3706	GGDEF domain
CK627_20130	COG3590	peptidase
CK627_20140	COG0488	(ABC) transporter
CK627_20150	COG0531	amino acid
CK627_20155	COG0814	amino acid
CK627_20170	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
CK627_20175	COG1982	Orn Lys Arg decarboxylase major
CK627_20180	COG0531	amino acid
CK627_20185	COG3710	Transcriptional regulator
CK627_20190	COG0825	malonyl-CoA metabolic process
CK627_20200	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
CK627_20205	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CK627_20210	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CK627_20215	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
CK627_20220	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CK627_20235	COG0750	zinc metalloprotease
CK627_20240	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
CK627_20245	COG0575	Belongs to the CDS family
CK627_20255	COG0233	cytoplasmic translational termination
CK627_20260	COG0528	UMP kinase activity
CK627_20265	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
CK627_20270	COG0052	Belongs to the universal ribosomal protein uS2 family
CK627_20275	COG0024	Methionine aminopeptidase
CK627_20280	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
CK627_20285	COG2171	N-acyltransferase activity
CK627_20295	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CK627_20295	COG1263	PTS System
CK627_20315	COG0564	pseudouridine synthase activity
CK627_20320	COG3098	single-species biofilm formation
CK627_20345	COG5595	Zn-ribbon-containing, possibly nucleic-acid-binding protein (DUF2310)
CK627_20355	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
CK627_20355	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
CK627_20365	COG3706	GGDEF domain
CK627_20370	COG1611	Belongs to the LOG family
CK627_20375	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CK627_20380	COG0473	3-isopropylmalate dehydrogenase activity
CK627_20390	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
CK627_20395	COG2363	Small membrane protein
CK627_20405	COG0583	DNA-binding transcription factor activity
CK627_20410	COG0840	transmembrane signaling receptor activity
CK627_20415	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CK627_20430	COG1477	protein flavinylation
CK627_20435	COG2871	sodium ion transport
CK627_20440	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
CK627_20445	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
CK627_20450	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
CK627_20455	COG1805	sodium ion transport
CK627_20460	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
CK627_20465	COG0271	Belongs to the BolA IbaG family
CK627_20470	COG2813	Specifically methylates the guanine in position
CK627_20480	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
CK627_20490	COG2211	Major facilitator Superfamily
CK627_20500	COG1666	GTP binding
CK627_20505	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
CK627_20510	COG0693	protein deglycase activity
CK627_20550	COG3501	Rhs element vgr protein
CK627_20565	COG2771	luxR family
CK627_20585	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
CK627_20585	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
CK627_20590	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
CK627_20595	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CK627_20600	COG1151	hydroxylamine reductase activity
CK627_20605	COG0783	Belongs to the Dps family
CK627_20630	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
CK627_20645	COG4221	oxidoreductase activity
CK627_20655	COG0415	Belongs to the DNA photolyase family
CK627_20660	COG0789	Transcriptional regulator
CK627_20665	COG3272	Protein of unknown function (DUF1722)
CK627_20695	COG1605	Chorismate mutase
CK627_20695	COG0077	Prephenate dehydratase
CK627_20720	COG1349	DNA-binding transcription factor activity
CK627_20725	COG2084	Dehydrogenase
CK627_20735	COG0235	Class ii aldolase
CK627_20740	COG3622	Belongs to the hyi family
CK627_20745	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CK627_20750	COG2610	gluconate transmembrane transporter activity
CK627_20760	COG0840	transmembrane signaling receptor activity
CK627_20770	COG0300	oxidoreductase activity
CK627_21025	COG0826	peptidase U32
CK627_21030	COG1280	lysine exporter protein (LysE YggA)
CK627_21060	COG2198	Histidine kinase
CK627_21060	COG0643	Histidine kinase
CK627_21070	COG0835	chemotaxis
CK627_21075	COG0840	transmembrane signaling receptor activity
CK627_21085	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
CK627_21090	COG2201	protein-glutamate methylesterase activity
CK627_21095	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
CK627_21120	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CK627_21120	COG2205	protein histidine kinase activity
CK627_21125	COG2197	response regulator
CK627_21150	COG2200	EAL domain
CK627_21150	COG2199	diguanylate cyclase activity
CK627_21150	COG2203	Gaf domain
CK627_21160	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
CK627_21165	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
CK627_21170	COG0305	Participates in initiation and elongation during chromosome replication
CK627_21185	COG2200	EAL domain
CK627_21190	COG0737	Belongs to the 5'-nucleotidase family
CK627_21210	COG2204	response regulator
CK627_21215	COG0545	Peptidyl-prolyl cis-trans isomerase
CK627_21225	COG2900	Belongs to the SlyX family
CK627_21230	COG1047	Peptidyl-prolyl cis-trans
CK627_21235	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
CK627_21245	COG0835	chemotaxis
CK627_21245	COG0784	Response regulator, receiver
CK627_21250	COG0429	hydrolase of the alpha beta-hydrolase fold
CK627_21255	COG3089	Belongs to the UPF0270 family
CK627_21265	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
CK627_21270	COG0463	Glycosyl transferase, family 2
CK627_21275	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CK627_21275	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
CK627_21280	COG0726	polysaccharide deacetylase
CK627_21285	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
CK627_21290	COG2076	Multidrug Resistance protein
CK627_21295	COG2076	Multidrug Resistance protein
CK627_21300	COG3954	Phosphoribulokinase
CK627_21315	COG1765	OsmC-like protein
CK627_21320	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CK627_21330	COG3397	chitin binding
CK627_21345	COG2205	protein histidine kinase activity
CK627_21345	COG2202	Pas domain
CK627_21355	COG3655	Transcriptional regulator
CK627_21365	COG2814	Major facilitator Superfamily
CK627_21375	COG4771	TonB-dependent receptor
CK627_21395	COG0748	coenzyme F420 binding
CK627_21400	COG3721	Heme iron utilization protein
CK627_21410	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CK627_21415	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
CK627_21440	COG0741	lytic transglycosylase activity
CK627_21445	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
CK627_21460	COG0488	(ABC) transporter
CK627_21470	COG2252	PERMEase
CK627_21475	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
CK627_21480	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
CK627_21485	COG3178	'Phosphotransferase
CK627_21490	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
CK627_21500	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
CK627_21505	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
CK627_21515	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
CK627_21525	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CK627_21530	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
CK627_21545	COG0318	PFAM AMP-dependent synthetase and ligase
CK627_21555	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
CK627_21560	COG0211	Belongs to the bacterial ribosomal protein bL27 family
CK627_21565	COG0261	This protein binds to 23S rRNA in the presence of protein L20
CK627_21570	COG0142	geranyltranstransferase activity
CK627_21575	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
CK627_21580	COG0330	HflC and HflK could
CK627_21585	COG0330	HflC and HflK could
CK627_21590	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
CK627_21595	COG1923	regulation of RNA biosynthetic process
CK627_21600	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
CK627_21605	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
CK627_21615	COG0802	atpase or kinase
CK627_21620	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
CK627_21620	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
CK627_21645	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
CK627_21650	COG2011	ABC-type metal ion transport system permease component
CK627_21655	COG1464	Belongs to the NlpA lipoprotein family
CK627_21665	COG0840	transmembrane signaling receptor activity
CK627_21690	COG5002	protein histidine kinase activity
CK627_21690	COG2198	Histidine kinase
CK627_21690	COG0784	Response regulator, receiver
CK627_21710	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
CK627_21725	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
CK627_21730	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
CK627_21740	COG2716	regulation of RNA biosynthetic process
CK627_21745	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
CK627_21750	COG3013	Belongs to the UPF0304 family
CK627_21755	COG3092	negative regulation of chromosome organization
CK627_21760	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
CK627_21765	COG0857	belongs to the CobB CobQ family
CK627_21765	COG0280	phosphate acetyltransferase
CK627_21770	COG0440	acetolactate synthase activity
CK627_21775	COG0028	Belongs to the TPP enzyme family
CK627_21790	COG0671	phosphoesterase, PA-phosphatase related
CK627_21800	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CK627_21805	COG0473	3-isopropylmalate dehydrogenase activity
CK627_21810	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
CK627_21815	COG0066	3-isopropylmalate dehydratase activity
CK627_21830	COG4143	(ABC) transporter
CK627_21835	COG1178	ABC-type Fe3 transport system permease component
CK627_21840	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
CK627_21845	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
CK627_21855	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CK627_21890	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
CK627_21895	COG0564	pseudouridine synthase activity
CK627_21905	COG2985	domain, Protein
CK627_21905	COG0569	domain protein
CK627_21910	COG1272	protein, Hemolysin III
CK627_21915	COG0076	glutamate decarboxylase activity
CK627_21920	COG2917	probably involved in intracellular septation
CK627_21925	COG2350	Protein conserved in bacteria
CK627_21935	COG1555	photosystem II stabilization
CK627_21940	COG1210	Utp--glucose-1-phosphate uridylyltransferase
CK627_21945	COG3104	oligopeptide transport
CK627_21950	COG0745	RESPONSE REGULATOR receiver
CK627_21980	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CK627_21995	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
CK627_22025	COG0316	Belongs to the HesB IscA family
CK627_22035	COG0038	chloride channel
CK627_22040	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
CK627_22055	COG0671	phosphoesterase, PA-phosphatase related
CK627_22065	COG0784	Response regulator, receiver
CK627_22065	COG3437	response regulator, receiver
CK627_22075	COG2076	Multidrug Resistance protein
CK627_22085	COG0346	lactoylglutathione lyase activity
CK627_22090	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CK627_22095	COG1643	Atp-dependent helicase
CK627_22105	COG1489	DNA binding
CK627_22110	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
CK627_22115	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CK627_22130	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
CK627_22135	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
CK627_22155	COG1924	4 iron, 4 sulfur cluster binding
CK627_22160	COG1775	2-hydroxyglutaryl-CoA dehydratase, D-component
CK627_22165	COG0842	Transport permease protein
CK627_22170	COG1131	(ABC) transporter
CK627_22185	COG0163	prenyltransferase activity
CK627_22190	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
CK627_22195	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
CK627_22210	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
CK627_22245	COG0840	transmembrane signaling receptor activity
CK627_22265	COG0529	Catalyzes the synthesis of activated sulfate
CK627_22270	COG3273	potassium ion transport
CK627_22270	COG0471	metal ion transport
CK627_22275	COG2895	sulfate adenylyltransferase (ATP) activity
CK627_22280	COG0175	sulfate reduction
CK627_22285	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
CK627_22285	COG1648	precorrin-2 dehydrogenase activity
CK627_22290	COG0330	HflC and HflK could
CK627_22295	COG1585	Membrane protein implicated in regulation of membrane protease activity
CK627_22300	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
CK627_22300	COG0517	IMP dehydrogenase activity
CK627_22305	COG0488	(ABC) transporter
CK627_22315	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
CK627_22345	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CK627_22355	COG0668	transmembrane transport
CK627_22365	COG2731	YhcH YjgK YiaL family protein
CK627_22380	COG1794	racemase activity, acting on amino acids and derivatives
CK627_22390	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CK627_22415	COG0733	neurotransmitter:sodium symporter activity
CK627_22425	COG0733	neurotransmitter:sodium symporter activity