locus-tag	class	description
FT673_00005	COG2314	TM2 domain
FT673_00145	COG0346	lactoylglutathione lyase activity
FT673_00175	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FT673_00235	COG1252	NADH dehydrogenase
FT673_00310	COG0537	adenosine 5'-monophosphoramidase activity
FT673_00350	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
FT673_00355	COG0861	Integral membrane protein TerC family
FT673_00370	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FT673_00375	COG0601	transmembrane transport
FT673_00415	COG1966	Carbon starvation protein
FT673_00440	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
FT673_00450	COG0436	Aminotransferase
FT673_00455	COG1288	antiporter activity
FT673_00460	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
FT673_00480	COG0697	spore germination
FT673_00485	COG4657	Part of a membrane complex involved in electron transport
FT673_00500	COG4658	electron transport chain
FT673_00510	COG4660	Part of a membrane complex involved in electron transport
FT673_00520	COG0346	lactoylglutathione lyase activity
FT673_00535	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
FT673_00570	COG1253	flavin adenine dinucleotide binding
FT673_00600	COG0367	asparagine synthase
FT673_00645	COG5001	Diguanylate cyclase
FT673_00670	COG2194	sulfuric ester hydrolase activity
FT673_00685	COG1317	bacterial-type flagellum organization
FT673_00850	COG4794	Type iii secretion
FT673_00880	COG0670	Belongs to the BI1 family
FT673_00890	COG2920	part of a sulfur-relay system
FT673_00920	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
FT673_00925	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FT673_00930	COG0671	phosphoesterase, PA-phosphatase related
FT673_00935	COG1464	Belongs to the NlpA lipoprotein family
FT673_01055	COG0765	amino acid transport
FT673_01060	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FT673_01075	COG0789	Transcriptional regulator
FT673_01100	COG0513	Belongs to the DEAD box helicase family
FT673_01105	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FT673_01145	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
FT673_01155	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
FT673_01165	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
FT673_01170	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
FT673_01175	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FT673_01180	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
FT673_01185	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
FT673_01220	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
FT673_01250	COG2119	membrane
FT673_01320	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
FT673_01330	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FT673_01335	COG3301	Polysulphide reductase, NrfD
FT673_01340	COG0437	4 iron, 4 sulfur cluster binding
FT673_01345	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
FT673_01405	COG2197	response regulator
FT673_01415	COG2835	tetraacyldisaccharide 4'-kinase activity
FT673_01555	COG2197	response regulator
FT673_01590	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
FT673_01595	COG1960	acyl-CoA dehydrogenase activity
FT673_01610	COG3385	transposase activity
FT673_01655	COG1749	Flagellar hook protein flgE
FT673_01685	COG0835	chemotaxis
FT673_01685	COG0784	Response regulator, receiver
FT673_01690	COG1261	Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly
FT673_01740	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
FT673_01750	COG1349	DNA-binding transcription factor activity
FT673_01785	COG1278	Cold shock
FT673_01835	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
FT673_01850	COG1091	dTDP-4-dehydrorhamnose reductase activity
FT673_01880	COG0438	transferase activity, transferring glycosyl groups
FT673_01920	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
FT673_01940	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FT673_01995	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
FT673_02095	COG4521	taurine ABC transporter
FT673_02125	COG0109	protoheme IX farnesyltransferase activity
FT673_02130	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
FT673_02135	COG1845	cytochrome c oxidase, subunit III
FT673_02205	COG0708	Exodeoxyribonuclease III
FT673_02250	COG0095	Lipoate-protein ligase
FT673_02295	COG1285	pathogenesis
FT673_02330	COG0443	Heat shock 70 kDa protein
FT673_02360	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FT673_02440	COG0531	amino acid
FT673_02445	COG0531	amino acid
FT673_02465	COG3384	dioxygenase
FT673_02485	COG0813	purine-nucleoside phosphorylase activity
FT673_02535	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
FT673_02565	COG0745	RESPONSE REGULATOR receiver
FT673_02625	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
FT673_02630	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
FT673_02640	COG2190	(PTS) system
FT673_02685	COG2974	May be involved in recombination
FT673_02695	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
FT673_02695	COG4651	solute:proton antiporter activity
FT673_02710	COG0469	pyruvate kinase activity
FT673_02715	COG3264	Mechanosensitive ion channel
FT673_02715	COG1196	nuclear chromosome segregation
FT673_02745	COG0281	malic enzyme
FT673_02915	COG4166	transmembrane transport
FT673_02930	COG0444	Belongs to the ABC transporter superfamily
FT673_02980	COG0616	signal peptide processing
FT673_02985	COG1028	Short-chain dehydrogenase reductase Sdr
FT673_03010	COG0583	DNA-binding transcription factor activity
FT673_03015	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
FT673_03035	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
FT673_03110	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
FT673_03145	COG1115	amino acid carrier protein
FT673_03150	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
FT673_03165	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
FT673_03175	COG1301	dicarboxylic acid transport
FT673_03180	COG2877	3-deoxy-8-phosphooctulonate synthase activity
FT673_03200	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
FT673_03210	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
FT673_03215	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
FT673_03240	COG0012	GTP binding
FT673_03315	COG0366	Alpha amylase catalytic
FT673_03325	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FT673_03325	COG1013	pyruvate-flavodoxin oxidoreductase activity
FT673_03325	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
FT673_03325	COG0674	pyruvate-flavodoxin oxidoreductase activity
FT673_03335	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FT673_03345	COG1012	belongs to the aldehyde dehydrogenase family
FT673_03370	COG0180	Tryptophanyl-tRNA synthetase
FT673_03380	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
FT673_03400	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
FT673_03455	COG0583	DNA-binding transcription factor activity
FT673_03470	COG0739	heme binding
FT673_03495	COG1053	succinate dehydrogenase
FT673_03500	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
FT673_03505	COG3029	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
FT673_03570	COG0642	Histidine kinase
FT673_03590	COG0516	GMP reductase activity
FT673_03600	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
FT673_03635	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FT673_03675	COG1702	phosphate starvation-inducible protein PhoH
FT673_03680	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
FT673_03685	COG4535	Mg2 and Co2 transporter CorC
FT673_03690	COG0815	Transfers the fatty acyl group on membrane lipoproteins
FT673_03700	COG0495	leucyl-tRNA aminoacylation
FT673_03720	COG0799	negative regulation of ribosome biogenesis
FT673_03725	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
FT673_03735	COG0772	Belongs to the SEDS family
FT673_03740	COG0772	Belongs to the SEDS family
FT673_03755	COG1686	Belongs to the peptidase S11 family
FT673_03760	COG2921	Belongs to the UPF0250 family
FT673_03785	COG3545	Serine hydrolase
FT673_03790	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
FT673_03920	COG1966	Carbon starvation protein
FT673_03965	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
FT673_03975	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
FT673_03985	COG0195	Participates in both transcription termination and antitermination
FT673_03990	COG0779	Required for maturation of 30S ribosomal subunits
FT673_04005	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
FT673_04010	COG0149	triose-phosphate isomerase activity
FT673_04030	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
FT673_04035	COG1534	Rna-binding protein
FT673_04050	COG1360	Flagellar Motor Protein
FT673_04060	COG1722	exodeoxyribonuclease VII activity
FT673_04095	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
FT673_04105	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
FT673_04130	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FT673_04130	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FT673_04135	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
FT673_04195	COG0511	ligase activity, forming carbon-carbon bonds
FT673_04200	COG0439	Biotin carboxylase
FT673_04230	COG2264	protein methyltransferase activity
FT673_04275	COG3139	Protein of unknown function (DUF1315)
FT673_04295	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
FT673_04300	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
FT673_04350	COG2966	Psort location CytoplasmicMembrane, score
FT673_04360	COG0521	Mo-molybdopterin cofactor biosynthetic process
FT673_04370	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FT673_04435	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FT673_04475	COG1858	cytochrome C peroxidase
FT673_04485	COG2313	pseudouridylate synthase activity
FT673_04490	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FT673_04565	COG4608	Belongs to the ABC transporter superfamily
FT673_04570	COG0444	Belongs to the ABC transporter superfamily
FT673_04600	COG0811	peptide transport
FT673_04660	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FT673_04675	COG1278	Cold shock
FT673_04730	COG4628	conserved protein (DUF2132)
FT673_04745	COG3059	membrane
FT673_04750	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
FT673_04755	COG2207	Transcriptional regulator
FT673_04770	COG3076	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome
FT673_04805	COG1132	(ABC) transporter
FT673_04825	COG2066	Belongs to the glutaminase family
FT673_04830	COG3171	Protein conserved in bacteria
FT673_04835	COG0220	tRNA (guanine-N7-)-methyltransferase activity
FT673_04840	COG4935	Belongs to the peptidase S8 family
FT673_04840	COG2234	aminopeptidase activity
FT673_04855	COG1090	epimerase
FT673_04865	COG4181	ATPase activity
FT673_04875	COG0784	Response regulator, receiver
FT673_04875	COG0835	chemotaxis
FT673_04920	COG2917	probably involved in intracellular septation
FT673_04925	COG2350	Protein conserved in bacteria
FT673_04935	COG1555	photosystem II stabilization
FT673_04985	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FT673_05000	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
FT673_05005	COG1280	lysine exporter protein (LysE YggA)
FT673_05030	COG0316	Belongs to the HesB IscA family
FT673_05045	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
FT673_05080	COG2076	Multidrug Resistance protein
FT673_05090	COG0346	lactoylglutathione lyase activity
FT673_05110	COG1489	DNA binding
FT673_05115	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
FT673_05120	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FT673_05190	COG0163	prenyltransferase activity
FT673_05200	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
FT673_05220	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
FT673_05235	COG1136	(ABC) transporter
FT673_05265	COG1484	DNA-dependent DNA replication
FT673_05270	COG4584	PFAM Integrase catalytic
FT673_05290	COG0529	Catalyzes the synthesis of activated sulfate
FT673_05295	COG0471	metal ion transport
FT673_05295	COG3273	potassium ion transport
FT673_05300	COG2895	sulfate adenylyltransferase (ATP) activity
FT673_05305	COG0175	sulfate reduction
FT673_05320	COG1585	Membrane protein implicated in regulation of membrane protease activity
FT673_05410	COG2731	YhcH YjgK YiaL family protein
FT673_05425	COG1794	racemase activity, acting on amino acids and derivatives
FT673_05520	COG1846	Transcriptional regulator
FT673_05525	COG1764	response to oxidative stress
FT673_05530	COG2130	NADP-dependent
FT673_05535	COG1051	belongs to the nudix hydrolase family
FT673_05565	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
FT673_05570	COG0676	glucose-6-phosphate 1-epimerase activity
FT673_05575	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
FT673_05655	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
FT673_05660	COG2885	chlorophyll binding
FT673_05680	COG0811	peptide transport
FT673_05685	COG0824	Thioesterase
FT673_05690	COG3790	cyd operon protein YbgE
FT673_05695	COG4890	Cyd operon protein YbgT
FT673_05700	COG1294	oxidase, subunit
FT673_05710	COG2255	four-way junction helicase activity
FT673_05725	COG0442	prolyl-tRNA aminoacylation
FT673_05730	COG4221	oxidoreductase activity
FT673_05745	COG1024	Enoyl-CoA hydratase
FT673_05785	COG0762	integral membrane protein
FT673_05790	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
FT673_05795	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
FT673_05810	COG3022	response to hydroperoxide
FT673_05815	COG0513	Belongs to the DEAD box helicase family
FT673_05845	COG0735	belongs to the Fur family
FT673_05850	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
FT673_05865	COG0776	regulation of translation
FT673_05925	COG0813	purine-nucleoside phosphorylase activity
FT673_05930	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
FT673_05935	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
FT673_05940	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
FT673_05950	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
FT673_05960	COG2165	general secretion pathway protein
FT673_05970	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
FT673_05975	COG0004	ammonium transporteR
FT673_05990	COG0795	lipopolysaccharide-transporting ATPase activity
FT673_05995	COG0795	lipopolysaccharide-transporting ATPase activity
FT673_06000	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
FT673_06010	COG0525	valine-tRNA ligase activity
FT673_06015	COG1253	flavin adenine dinucleotide binding
FT673_06020	COG0586	Pfam SNARE associated Golgi protein
FT673_06060	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
FT673_06070	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
FT673_06080	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
FT673_06085	COG1546	Belongs to the CinA family
FT673_06110	COG3068	Protein conserved in bacteria
FT673_06150	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FT673_06170	COG2962	Rard protein
FT673_06300	COG3150	esterase
FT673_06315	COG0494	nUDIX hydrolase
FT673_06325	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
FT673_06325	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
FT673_06330	COG1560	Kdo2-lipid A biosynthetic process
FT673_06345	COG1392	Phosphate transport regulator
FT673_06350	COG0306	phosphate transporter
FT673_06390	COG1380	Effector of murein hydrolase LrgA
FT673_06415	COG3267	Type II secretory pathway component ExeA
FT673_06415	COG3409	Peptidoglycan-binding domain 1 protein
FT673_06425	COG1194	a g-specific adenine glycosylase
FT673_06430	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
FT673_06440	COG3111	PFAM Bacterial OB fold (BOF) protein
FT673_06455	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
FT673_06455	COG2885	chlorophyll binding
FT673_06460	COG3009	Protein conserved in bacteria
FT673_06465	COG3008	intermembrane lipid transfer
FT673_06465	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
FT673_06490	COG3706	GGDEF domain
FT673_06490	COG2203	Gaf domain
FT673_06490	COG5001	Diguanylate cyclase
FT673_06490	COG4251	negative regulation of phosphorylation
FT673_06495	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FT673_06505	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
FT673_06555	COG0583	DNA-binding transcription factor activity
FT673_06580	COG1012	belongs to the aldehyde dehydrogenase family
FT673_06600	COG0110	maltose O-acetyltransferase activity
FT673_06610	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FT673_06610	COG1263	PTS System
FT673_06630	COG0252	asparaginase activity
FT673_06645	COG1803	Methylglyoxal synthase
FT673_06670	COG1444	tRNA N-acetyltransferase activity
FT673_06675	COG1028	Short-chain dehydrogenase reductase Sdr
FT673_06680	COG0784	Response regulator, receiver
FT673_06680	COG0835	chemotaxis
FT673_06725	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
FT673_06730	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
FT673_06770	COG2200	EAL domain
FT673_06775	COG1049	propionate catabolic process, 2-methylcitrate cycle
FT673_06785	COG0840	transmembrane signaling receptor activity
FT673_06800	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FT673_06805	COG0508	dehydrogenase complex catalyzes the overall conversion of
FT673_06815	COG2186	Transcriptional regulator
FT673_06845	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
FT673_06865	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
FT673_06895	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
FT673_06900	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
FT673_06905	COG0849	cell division
FT673_06915	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
FT673_06925	COG0772	Belongs to the SEDS family
FT673_06930	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
FT673_06940	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
FT673_06955	COG3116	cell division
FT673_06960	COG0275	rRNA processing
FT673_06965	COG2001	Belongs to the MraZ family
FT673_06990	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
FT673_06995	COG1191	sigma factor activity
FT673_07025	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
FT673_07075	COG1749	Flagellar hook protein flgE
FT673_07090	COG1815	bacterial-type flagellum-dependent cell motility
FT673_07125	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
FT673_07135	COG1677	Flagellar hook-basal body complex protein FliE
FT673_07160	COG1987	bacterial-type flagellum assembly
FT673_07185	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
FT673_07195	COG0792	nuclease activity
FT673_07200	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
FT673_07205	COG2823	Periplasmic or secreted lipoprotein
FT673_07215	COG0625	glutathione transferase activity
FT673_07235	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
FT673_07240	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
FT673_07255	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FT673_07310	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
FT673_07335	COG1137	ATPase activity
FT673_07340	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
FT673_07345	COG3117	lipopolysaccharide transmembrane transporter activity
FT673_07355	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
FT673_07355	COG0517	IMP dehydrogenase activity
FT673_07360	COG1127	ABC transporter
FT673_07365	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
FT673_07370	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
FT673_07390	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
FT673_07395	COG0312	modulator of DNA gyrase
FT673_07400	COG3028	Belongs to the UPF0307 family
FT673_07410	COG2926	Belongs to the UPF0265 family
FT673_07445	COG3135	benzoate transporter
FT673_07475	COG3047	cAMP biosynthetic process
FT673_07490	COG2197	response regulator
FT673_07495	COG0629	single-stranded DNA binding
FT673_07595	COG2259	Doxx family
FT673_07600	COG1741	Belongs to the pirin family
FT673_07635	COG1176	ABC-type spermidine putrescine transport system, permease component I
FT673_07720	COG2957	Belongs to the agmatine deiminase family
FT673_07745	COG1461	Dihydroxyacetone kinase
FT673_07750	COG2376	Dihydroxyacetone kinase
FT673_07755	COG2252	PERMEase
FT673_07790	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
FT673_07795	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
FT673_07800	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
FT673_07805	COG0049	tRNA binding
FT673_07810	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
FT673_07815	COG2168	tRNA wobble position uridine thiolation
FT673_07820	COG2923	Belongs to the DsrF TusC family
FT673_07830	COG0251	oxidation-reduction process
FT673_07835	COG2964	Protein conserved in bacteria
FT673_07845	COG0085	RNA polymerase activity
FT673_07850	COG0222	ribosome binding
FT673_07855	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
FT673_07860	COG0081	regulation of translation
FT673_07865	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
FT673_07870	COG0250	Participates in transcription elongation, termination and antitermination
FT673_07885	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
FT673_07915	COG0569	domain protein
FT673_07945	COG3005	denitrification pathway
FT673_08010	COG2205	protein histidine kinase activity
FT673_08035	COG5413	integral membrane protein
FT673_08045	COG1522	sequence-specific DNA binding
FT673_08050	COG2502	aspartate--ammonia ligase
FT673_08060	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
FT673_08080	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FT673_08095	COG3681	Belongs to the UPF0597 family
FT673_08105	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
FT673_08125	COG3040	lipid binding
FT673_08135	COG0688	phosphatidylethanolamine metabolic process
FT673_08150	COG0540	Belongs to the ATCase OTCase family
FT673_08155	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
FT673_08160	COG1438	arginine binding
FT673_08170	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
FT673_08240	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
FT673_08255	COG1968	undecaprenyl-diphosphatase activity
FT673_08260	COG3806	Anti-sigma factor
FT673_08265	COG1595	DNA-templated transcription, initiation
FT673_08285	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
FT673_08305	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FT673_08335	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
FT673_08340	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
FT673_08365	COG2050	protein possibly involved in aromatic compounds catabolism
FT673_08390	COG1176	ABC-type spermidine putrescine transport system, permease component I
FT673_08435	COG3045	CreA protein
FT673_08440	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FT673_08445	COG0443	Heat shock 70 kDa protein
FT673_08460	COG0366	Alpha amylase catalytic
FT673_08465	COG1086	Polysaccharide biosynthesis protein
FT673_08470	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
FT673_08475	COG4750	Nucleotidyl transferase
FT673_08485	COG3848	Pyruvate phosphate dikinase
FT673_08485	COG0574	Belongs to the PEP-utilizing enzyme family
FT673_08490	COG0529	Catalyzes the synthesis of activated sulfate
FT673_08510	COG0438	transferase activity, transferring glycosyl groups
FT673_08525	COG1215	transferase activity, transferring glycosyl groups
FT673_08540	COG0318	PFAM AMP-dependent synthetase and ligase
FT673_08545	COG1028	Short-chain dehydrogenase reductase Sdr
FT673_08560	COG1083	cytidylyl-transferase
FT673_08625	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
FT673_08645	COG0281	malic enzyme
FT673_08655	COG0254	rRNA binding
FT673_08690	COG3978	acetolactate synthase activity
FT673_08710	COG0204	Acyl-transferase
FT673_08735	COG1335	isochorismatase
FT673_08760	COG3084	Protein conserved in bacteria
FT673_08780	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
FT673_08785	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
FT673_08805	COG3306	glycosyltransferase involved in LPS biosynthesis
FT673_08820	COG0438	transferase activity, transferring glycosyl groups
FT673_08825	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FT673_08835	COG0156	8-amino-7-oxononanoate synthase activity
FT673_08845	COG3245	cytochrome
FT673_08860	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
FT673_08865	COG2166	iron-sulfur cluster assembly
FT673_08870	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
FT673_08915	COG0583	DNA-binding transcription factor activity
FT673_08930	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
FT673_08945	COG3279	Response regulator of the LytR AlgR family
FT673_08950	COG3275	phosphorelay sensor kinase activity
FT673_08955	COG2205	protein histidine kinase activity
FT673_08955	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FT673_08960	COG2205	protein histidine kinase activity
FT673_08960	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FT673_09035	COG1528	Iron-storage protein
FT673_09045	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
FT673_09050	COG0589	response to stress
FT673_09090	COG3642	lipopolysaccharide core region biosynthetic process
FT673_09095	COG0859	PFAM glycosyl transferase family 9
FT673_09115	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FT673_09120	COG2267	carboxylic ester hydrolase activity
FT673_09125	COG0561	phosphatase activity
FT673_09155	COG1309	transcriptional regulator
FT673_09160	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FT673_09170	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FT673_09170	COG4191	Histidine kinase
FT673_09175	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FT673_09205	COG3385	transposase activity
FT673_09270	COG3328	transposase activity
FT673_09310	COG5001	Diguanylate cyclase
FT673_09310	COG3300	MHYT domain
FT673_09350	COG0732	type I restriction modification DNA specificity domain
FT673_09385	COG4974	Belongs to the 'phage' integrase family
FT673_09390	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
FT673_09395	COG0706	membrane insertase activity
FT673_09400	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
FT673_09405	COG0594	ribonuclease P activity
FT673_09410	COG0230	Belongs to the bacterial ribosomal protein bL34 family
FT673_09430	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
FT673_09435	COG0592	DNA-directed DNA polymerase activity
FT673_09440	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
FT673_09455	COG2378	regulation of single-species biofilm formation
FT673_09465	COG0071	Belongs to the small heat shock protein (HSP20) family
FT673_09530	COG3550	peptidyl-serine autophosphorylation
FT673_09575	COG1484	DNA-dependent DNA replication
FT673_09615	COG3550	peptidyl-serine autophosphorylation
FT673_09630	COG1120	ATPase activity
FT673_09645	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
FT673_09650	COG0445	tRNA wobble uridine modification
FT673_09655	COG0357	Ribosomal RNA small subunit methyltransferase G
FT673_09660	COG1192	Involved in chromosome partitioning
FT673_09665	COG1475	DNA binding
FT673_09685	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
FT673_09690	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
FT673_09695	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
FT673_09705	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
FT673_09710	COG0355	proton-transporting ATP synthase activity, rotational mechanism
FT673_09715	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
FT673_09720	COG4452	Inner membrane protein CreD
FT673_09735	COG0745	RESPONSE REGULATOR receiver
FT673_09740	COG1349	DNA-binding transcription factor activity
FT673_09745	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
FT673_09790	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
FT673_09820	COG2771	luxR family
FT673_09830	COG0811	peptide transport
FT673_09835	COG0811	peptide transport
FT673_09845	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
FT673_09890	COG0402	S-adenosylhomocysteine deaminase activity
FT673_09895	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
FT673_09905	COG3165	ubiquinone biosynthetic process from chorismate
FT673_09910	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
FT673_09920	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
FT673_09925	COG0805	protein transport
FT673_09930	COG0084	hydrolase, TatD family'
FT673_09965	COG0248	Ppx GppA phosphatase
FT673_09970	COG0513	Belongs to the DEAD box helicase family
FT673_09975	COG3118	belongs to the thioredoxin family
FT673_10015	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FT673_10055	COG1609	Transcriptional regulator
FT673_10065	COG1773	rubredoxin
FT673_10065	COG0426	domain, Protein
FT673_10080	COG0348	domain, Protein
FT673_10085	COG0814	amino acid
FT673_10135	COG0752	glycyl-tRNA synthetase alpha subunit
FT673_10195	COG0183	Belongs to the thiolase family
FT673_10205	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FT673_10210	COG0006	proline dipeptidase activity
FT673_10225	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
FT673_10250	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FT673_10250	COG1042	CoA-binding domain protein
FT673_10250	COG0045	succinate-CoA ligase (ADP-forming) activity
FT673_10270	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
FT673_10275	COG0166	Belongs to the GPI family
FT673_10290	COG0668	transmembrane transport
FT673_10305	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
FT673_10310	COG2003	Belongs to the UPF0758 family
FT673_10315	COG0227	Belongs to the bacterial ribosomal protein bL28 family
FT673_10320	COG0267	Belongs to the bacterial ribosomal protein bL33 family
FT673_10330	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
FT673_10335	COG2990	Protein conserved in bacteria
FT673_10340	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
FT673_10350	COG0463	Glycosyl transferase, family 2
FT673_10355	COG0859	PFAM glycosyl transferase family 9
FT673_10385	COG0604	alcohol dehydrogenase
FT673_10410	COG3161	chorismate lyase activity
FT673_10415	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
FT673_10425	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
FT673_10455	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
FT673_10465	COG0745	RESPONSE REGULATOR receiver
FT673_10485	COG3074	FtsZ-dependent cytokinesis
FT673_10500	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FT673_10500	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FT673_10540	COG1609	Transcriptional regulator
FT673_10605	COG4603	Belongs to the binding-protein-dependent transport system permease family
FT673_10610	COG3845	ABC transporter
FT673_10615	COG1744	ABC transporter substrate-binding protein PnrA-like
FT673_10695	COG2391	methyltransferase activity
FT673_10730	COG1012	belongs to the aldehyde dehydrogenase family
FT673_10735	COG1396	sequence-specific DNA binding
FT673_10760	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FT673_10780	COG1322	Protein conserved in bacteria
FT673_10790	COG0569	domain protein
FT673_10795	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
FT673_10795	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
FT673_10800	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
FT673_10805	COG0242	peptide deformylase activity
FT673_10815	COG0758	DNA mediated transformation
FT673_10820	COG2922	Belongs to the Smg family
FT673_10825	COG0551	DNA topoisomerase type I activity
FT673_10840	COG0408	coproporphyrinogen oxidase activity
FT673_10845	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
FT673_10855	COG0218	Necessary for normal cell division and for the maintenance of normal septation
FT673_10870	COG3078	GTPase activator activity
FT673_10885	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
FT673_10905	COG0174	glutamine synthetase
FT673_10910	COG1217	gtp-binding protein TYPA
FT673_10920	COG1295	ribonuclease BN
FT673_10955	COG2610	gluconate transmembrane transporter activity
FT673_10960	COG3265	gluconokinase activity
FT673_10965	COG0129	dihydroxy-acid dehydratase activity
FT673_10970	COG0800	Aldolase
FT673_10975	COG1609	Transcriptional regulator
FT673_10985	COG4942	peptidase
FT673_10990	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
FT673_11000	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
FT673_11010	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
FT673_11010	COG0316	Belongs to the HesB IscA family
FT673_11020	COG0596	Alpha beta hydrolase
FT673_11045	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
FT673_11070	COG0051	transcription antitermination factor activity, RNA binding
FT673_11075	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
FT673_11080	COG0088	Forms part of the polypeptide exit tunnel
FT673_11085	COG0089	rRNA binding
FT673_11090	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
FT673_11095	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
FT673_11100	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
FT673_11105	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
FT673_11110	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
FT673_11115	COG0255	Belongs to the universal ribosomal protein uL29 family
FT673_11120	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
FT673_11135	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
FT673_11140	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
FT673_11145	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
FT673_11150	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
FT673_11155	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
FT673_11160	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
FT673_11165	COG1841	ribosomal large subunit assembly
FT673_11170	COG0200	Binds to the 23S rRNA
FT673_11175	COG0201	protein transport
FT673_11180	COG0257	Belongs to the bacterial ribosomal protein bL36 family
FT673_11185	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
FT673_11190	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
FT673_11195	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
FT673_11200	COG0202	RNA polymerase activity
FT673_11205	COG0203	ribosomal protein L17
FT673_11255	COG4584	PFAM Integrase catalytic
FT673_11325	COG3714	YhhN family
FT673_11360	COG2095	MarC family integral membrane protein
FT673_11370	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
FT673_11425	COG2177	Part of the ABC transporter FtsEX involved in
FT673_11440	COG2188	Transcriptional regulator
FT673_11455	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
FT673_11460	COG2986	histidine ammonia-lyase
FT673_11470	COG2200	EAL domain
FT673_11540	COG4969	Belongs to the N-Me-Phe pilin family
FT673_11545	COG4968	Prepilin-type N-terminal cleavage methylation domain
FT673_11570	COG1077	Cell shape determining protein MreB Mrl
FT673_11580	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
FT673_11585	COG0424	maF-like protein
FT673_11590	COG1530	ribonuclease E activity
FT673_11605	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FT673_11625	COG0477	Major facilitator Superfamily
FT673_11635	COG3437	response regulator, receiver
FT673_11650	COG1366	Belongs to the anti-sigma-factor antagonist family
FT673_11670	COG3700	Belongs to the class B bacterial acid phosphatase family
FT673_11675	COG2321	neutral zinc metallopeptidase
FT673_11720	COG0642	Histidine kinase
FT673_11740	COG3766	membrane
FT673_11750	COG0754	glutathionylspermidine amidase activity
FT673_11765	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
FT673_11780	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
FT673_11795	COG3417	Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1B (PBP1b)
FT673_11840	COG1733	regulation of RNA biosynthetic process
FT673_11895	COG2959	enzyme of heme biosynthesis
FT673_11920	COG1965	Belongs to the frataxin family
FT673_11975	COG0561	phosphatase activity
FT673_12020	COG1522	sequence-specific DNA binding
FT673_12065	COG4221	oxidoreductase activity
FT673_12095	COG2873	o-acetylhomoserine
FT673_12150	COG3291	Pkd domain containing protein
FT673_12160	COG3539	Fimbrial protein
FT673_12210	COG0596	Alpha beta hydrolase
FT673_12220	COG1169	isochorismate synthase
FT673_12255	COG0513	Belongs to the DEAD box helicase family
FT673_12260	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
FT673_12265	COG1988	membrane-bound metal-dependent
FT673_12305	COG3263	regulation of cellular component size
FT673_12310	COG3722	fumarate hydratase activity
FT673_12315	COG0246	Mannitol dehydrogenase
FT673_12320	COG2213	PTS system mannitol-specific
FT673_12320	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
FT673_12330	COG1309	transcriptional regulator
FT673_12365	COG3133	Outer membrane lipoprotein
FT673_12370	COG0456	acetyltransferase
FT673_12390	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
FT673_12395	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
FT673_12405	COG3031	protein transport across the cell outer membrane
FT673_12415	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
FT673_12440	COG2165	general secretion pathway protein
FT673_12445	COG4795	General secretion pathway protein
FT673_12460	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
FT673_12475	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
FT673_12480	COG1011	Hydrolase
FT673_12485	COG0494	nUDIX hydrolase
FT673_12490	COG1218	3'(2'),5'-bisphosphate nucleotidase
FT673_12520	COG0527	aspartate kinase activity
FT673_12520	COG0460	homoserine dehydrogenase
FT673_12545	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
FT673_12560	COG0165	Argininosuccinate lyase
FT673_12585	COG0110	maltose O-acetyltransferase activity
FT673_12590	COG3174	membrane
FT673_12605	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
FT673_12610	COG4208	sulfate ABC transporter
FT673_12615	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
FT673_12620	COG0583	DNA-binding transcription factor activity
FT673_12625	COG3397	chitin binding
FT673_12630	COG0840	transmembrane signaling receptor activity
FT673_12690	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
FT673_12705	COG1448	Aminotransferase
FT673_12745	COG0513	Belongs to the DEAD box helicase family
FT673_12765	COG0840	transmembrane signaling receptor activity
FT673_12780	COG3112	Uncharacterised protein family (UPF0231)
FT673_12795	COG1929	Belongs to the glycerate kinase type-1 family
FT673_12815	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
FT673_12830	COG0347	Belongs to the P(II) protein family
FT673_12835	COG1840	ABC-type Fe3 transport system, periplasmic component
FT673_12845	COG3842	ATPase activity
FT673_12850	COG2837	iron assimilation
FT673_12855	COG1438	arginine binding
FT673_12865	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FT673_12870	COG4215	(ABC) transporter
FT673_12875	COG4160	amino acid transport
FT673_12880	COG0039	L-malate dehydrogenase activity
FT673_12895	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
FT673_12895	COG1017	nitric oxide dioxygenase activity
FT673_12915	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
FT673_12920	COG0228	four-way junction DNA binding
FT673_12925	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
FT673_12930	COG0336	Belongs to the RNA methyltransferase TrmD family
FT673_12935	COG0335	large ribosomal subunit rRNA binding
FT673_12960	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
FT673_12985	COG0640	Transcriptional regulator
FT673_12990	COG0268	Binds directly to 16S ribosomal RNA
FT673_13025	COG4970	Tfp pilus assembly protein FimT
FT673_13100	COG3706	GGDEF domain
FT673_13105	COG0557	exoribonuclease II activity
FT673_13140	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FT673_13150	COG2153	protein acetylation
FT673_13165	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
FT673_13170	COG1914	H( )-stimulated, divalent metal cation uptake system
FT673_13175	COG0360	Binds together with S18 to 16S ribosomal RNA
FT673_13180	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
FT673_13185	COG0359	binds to the 23S rRNA
FT673_13215	COG1238	metal cluster binding
FT673_13225	COG2918	glutathione biosynthetic process
FT673_13235	COG1022	Amp-dependent synthetase and ligase
FT673_13245	COG0456	acetyltransferase
FT673_13255	COG0714	Associated with various cellular activities
FT673_13265	COG5001	Diguanylate cyclase
FT673_13265	COG3300	MHYT domain
FT673_13295	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
FT673_13325	COG3846	protein secretion by the type IV secretion system
FT673_13350	COG3838	Conjugal transfer protein Trbc
FT673_13385	COG2076	Multidrug Resistance protein
FT673_13435	COG1127	ABC transporter
FT673_13460	COG4959	Type IV secretory pathway protease TraF
FT673_13510	COG1396	sequence-specific DNA binding
FT673_13520	COG5489	Protein of unknown function (DUF736)
FT673_13550	COG2003	Belongs to the UPF0758 family
FT673_13570	COG3621	Patatin-like phospholipase
FT673_13590	COG4804	nuclease activity
FT673_13600	COG1902	pentaerythritol trinitrate reductase activity
FT673_13610	COG2852	Protein conserved in bacteria
FT673_13620	COG2957	Belongs to the agmatine deiminase family
FT673_13750	COG0745	RESPONSE REGULATOR receiver
FT673_13760	COG1136	(ABC) transporter
FT673_13760	COG0577	efflux transmembrane transporter activity
FT673_13770	COG1126	abc transporter atp-binding protein
FT673_13775	COG0765	amino acid transport
FT673_13830	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FT673_13835	COG4991	sh3 domain protein
FT673_13850	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
FT673_13855	COG1940	carbohydrate kinase activity
FT673_13860	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
FT673_13865	COG0126	phosphoglycerate kinase activity
FT673_13920	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
FT673_13930	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
FT673_13935	COG1595	DNA-templated transcription, initiation
FT673_13940	COG3073	An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E
FT673_13955	COG0481	GTPase activity
FT673_13965	COG0571	ribonuclease III activity
FT673_13975	COG1381	Involved in DNA repair and RecF pathway recombination
FT673_14000	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
FT673_14005	COG3716	PTS system mannose fructose sorbose family IID component
FT673_14015	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FT673_14030	COG1349	DNA-binding transcription factor activity
FT673_14040	COG4807	Protein conserved in bacteria
FT673_14050	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
FT673_14060	COG3956	TIGRFAM MazG family protein
FT673_14065	COG0504	CTP synthase activity
FT673_14070	COG0148	phosphopyruvate hydratase activity
FT673_14075	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
FT673_14100	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
FT673_14125	COG0828	Belongs to the bacterial ribosomal protein bS21 family
FT673_14130	COG1610	YqeY-like protein
FT673_14180	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
FT673_14185	COG3036	rescue of stalled ribosome
FT673_14190	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FT673_14195	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
FT673_14250	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
FT673_14255	COG1027	Aspartate ammonia-lyase
FT673_14265	COG0534	Mate efflux family protein
FT673_14270	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
FT673_14275	COG0459	protein refolding
FT673_14285	COG5001	Diguanylate cyclase
FT673_14285	COG3300	MHYT domain
FT673_14295	COG0564	pseudouridine synthase activity
FT673_14370	COG0066	3-isopropylmalate dehydratase activity
FT673_14375	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
FT673_14380	COG0473	3-isopropylmalate dehydrogenase activity
FT673_14395	COG0671	phosphoesterase, PA-phosphatase related
FT673_14425	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
FT673_14440	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
FT673_14495	COG5002	protein histidine kinase activity
FT673_14495	COG2198	Histidine kinase
FT673_14495	COG0784	Response regulator, receiver
FT673_14520	COG0840	transmembrane signaling receptor activity
FT673_14530	COG1464	Belongs to the NlpA lipoprotein family
FT673_14535	COG2011	ABC-type metal ion transport system permease component
FT673_14555	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
FT673_14560	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
FT673_14560	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
FT673_14565	COG0802	atpase or kinase
FT673_14580	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
FT673_14585	COG1923	regulation of RNA biosynthetic process
FT673_14600	COG0330	HflC and HflK could
FT673_14610	COG0142	geranyltranstransferase activity
FT673_14615	COG0261	This protein binds to 23S rRNA in the presence of protein L20
FT673_14620	COG0211	Belongs to the bacterial ribosomal protein bL27 family
FT673_14625	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
FT673_14665	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
FT673_14695	COG3178	'Phosphotransferase
FT673_14700	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
FT673_14710	COG2252	PERMEase
FT673_14720	COG0488	(ABC) transporter
FT673_14735	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
FT673_14740	COG0741	lytic transglycosylase activity
FT673_14760	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
FT673_14810	COG0748	coenzyme F420 binding
FT673_14840	COG2814	Major facilitator Superfamily
FT673_14845	COG3655	Transcriptional regulator
FT673_14875	COG2226	methyltransferase
FT673_14885	COG1765	OsmC-like protein
FT673_14910	COG2076	Multidrug Resistance protein
FT673_14930	COG0463	Glycosyl transferase, family 2
FT673_14960	COG0835	chemotaxis
FT673_14960	COG0784	Response regulator, receiver
FT673_14970	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
FT673_14990	COG0545	Peptidyl-prolyl cis-trans isomerase
FT673_15015	COG0737	Belongs to the 5'-nucleotidase family
FT673_15035	COG0305	Participates in initiation and elongation during chromosome replication
FT673_15055	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
FT673_15090	COG2197	response regulator
FT673_15095	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FT673_15095	COG2205	protein histidine kinase activity
FT673_15120	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
FT673_15130	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
FT673_15145	COG0835	chemotaxis
FT673_15185	COG1280	lysine exporter protein (LysE YggA)
FT673_15190	COG0826	peptidase U32
FT673_15240	COG0300	oxidoreductase activity
FT673_15285	COG1605	Chorismate mutase
FT673_15285	COG0077	Prephenate dehydratase
FT673_15375	COG0783	Belongs to the Dps family
FT673_15395	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
FT673_15395	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
FT673_15410	COG2831	hemolysin activation secretion protein
FT673_15430	COG3210	domain, Protein
FT673_15445	COG4584	PFAM Integrase catalytic
FT673_15450	COG1484	DNA-dependent DNA replication
FT673_15460	COG3210	domain, Protein
FT673_15485	COG2771	luxR family
FT673_15560	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
FT673_15565	COG1666	GTP binding
FT673_15600	COG0271	Belongs to the BolA IbaG family
FT673_15610	COG1805	sodium ion transport
FT673_15620	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
FT673_15625	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
FT673_15630	COG2871	sodium ion transport
FT673_15655	COG0840	transmembrane signaling receptor activity
FT673_15660	COG0583	DNA-binding transcription factor activity
FT673_15670	COG2363	Small membrane protein
FT673_15690	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FT673_15695	COG1611	Belongs to the LOG family
FT673_15710	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
FT673_15710	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
FT673_15720	COG5595	Zn-ribbon-containing, possibly nucleic-acid-binding protein (DUF2310)
FT673_15745	COG3098	single-species biofilm formation
FT673_15750	COG0564	pseudouridine synthase activity
FT673_15770	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FT673_15770	COG1263	PTS System
FT673_15800	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
FT673_15810	COG0233	cytoplasmic translational termination
FT673_15850	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
FT673_15865	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
FT673_15875	COG0825	malonyl-CoA metabolic process
FT673_15890	COG0531	amino acid
FT673_15915	COG0814	amino acid
FT673_15920	COG0531	amino acid
FT673_15940	COG3590	peptidase
FT673_15950	COG3706	GGDEF domain
FT673_16015	COG2989	Protein conserved in bacteria
FT673_16020	COG3108	Peptidase M15
FT673_16030	COG2860	membrane
FT673_16045	COG3115	cell septum assembly
FT673_16060	COG1328	CTP reductase activity
FT673_16065	COG0602	queuosine metabolic process
FT673_16095	COG1566	PFAM secretion protein HlyD family protein
FT673_16100	COG1846	Transcriptional regulator
FT673_16125	COG4565	transcriptional regulatory protein
FT673_16160	COG0346	lactoylglutathione lyase activity
FT673_16200	COG0545	Peptidyl-prolyl cis-trans isomerase
FT673_16205	COG1131	(ABC) transporter
FT673_16225	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
FT673_16235	COG0678	peroxiredoxin activity
FT673_16245	COG0019	diaminopimelate decarboxylase activity
FT673_16285	COG0281	malic enzyme
FT673_16320	COG1752	Esterase of the alpha-beta hydrolase superfamily
FT673_16330	COG1566	PFAM secretion protein HlyD family protein
FT673_16345	COG1032	radical SAM domain protein
FT673_16365	COG3152	Membrane
FT673_16385	COG0673	inositol 2-dehydrogenase activity
FT673_16395	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
FT673_16440	COG0788	formyltetrahydrofolate deformylase activity
FT673_16445	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FT673_16465	COG0791	NLP P60 protein
FT673_16510	COG4869	propanediol catabolic process
FT673_16530	COG1454	alcohol dehydrogenase
FT673_16530	COG1012	belongs to the aldehyde dehydrogenase family
FT673_16540	COG1454	alcohol dehydrogenase
FT673_16540	COG1012	belongs to the aldehyde dehydrogenase family
FT673_16640	COG1136	(ABC) transporter
FT673_16665	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
FT673_16690	COG0469	pyruvate kinase activity
FT673_16695	COG1737	Transcriptional regulator
FT673_16715	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
FT673_16795	COG2132	Multicopper oxidase
FT673_16830	COG5002	protein histidine kinase activity
FT673_16835	COG0745	RESPONSE REGULATOR receiver
FT673_16845	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FT673_16855	COG1538	Outer membrane efflux protein
FT673_16870	COG5642	Protein of unknown function (DUF2384)
FT673_16905	COG1677	Flagellar hook-basal body complex protein FliE
FT673_17005	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
FT673_17025	COG1360	Flagellar Motor Protein
FT673_17040	COG0835	chemotaxis
FT673_17060	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
FT673_17065	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
FT673_17070	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
FT673_17085	COG3088	subunit of a heme lyase
FT673_17085	COG4235	cytochrome complex assembly
FT673_17105	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
FT673_17110	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
FT673_17110	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
FT673_17150	COG2850	peptidyl-arginine hydroxylation
FT673_17155	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
FT673_17160	COG2915	High frequency lysogenization protein hflD homolog
FT673_17185	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FT673_17185	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FT673_17185	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FT673_17235	COG1609	Transcriptional regulator
FT673_17240	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FT673_17240	COG1263	PTS System
FT673_17245	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
FT673_17285	COG0538	isocitrate dehydrogenase activity
FT673_17295	COG3048	D-serine ammonia-lyase activity
FT673_17300	COG0583	DNA-binding transcription factor activity
FT673_17330	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
FT673_17340	COG2914	Belongs to the UPF0125 (RnfH) family
FT673_17345	COG0702	epimerase
FT673_17350	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FT673_17355	COG1454	alcohol dehydrogenase
FT673_17365	COG0564	pseudouridine synthase activity
FT673_17395	COG1280	lysine exporter protein (LysE YggA)
FT673_17425	COG1876	peptidase activity
FT673_17435	COG1393	Belongs to the ArsC family
FT673_17450	COG3069	C4-dicarboxylate transmembrane transporter activity
FT673_17470	COG0017	Asparaginyl-tRNA synthetase
FT673_17495	COG0156	8-amino-7-oxononanoate synthase activity
FT673_17625	COG0450	alkyl hydroperoxide reductase
FT673_17645	COG0500	methyltransferase
FT673_17650	COG4106	trans-aconitate 2-methyltransferase activity
FT673_17665	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
FT673_17670	COG0217	transcriptional regulatory protein
FT673_17710	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FT673_17715	COG0735	belongs to the Fur family
FT673_17725	COG0716	FMN binding
FT673_17745	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
FT673_17750	COG0033	Phosphoglucomutase
FT673_17780	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
FT673_17785	COG4136	ATPase activity
FT673_17805	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
FT673_17815	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FT673_17820	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FT673_17855	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
FT673_17865	COG0741	lytic transglycosylase activity
FT673_17880	COG1607	acyl-coa hydrolase
FT673_17890	COG3021	interspecies interaction between organisms
FT673_17910	COG0328	RNA-DNA hybrid ribonuclease activity
FT673_17935	COG2716	regulation of RNA biosynthetic process
FT673_17960	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
FT673_17970	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
FT673_17975	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
FT673_18025	COG0704	Plays a role in the regulation of phosphate uptake
FT673_18030	COG1253	flavin adenine dinucleotide binding
FT673_18070	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FT673_18095	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
FT673_18165	COG1448	Aminotransferase
FT673_18180	COG0302	gtp cyclohydrolase
FT673_18185	COG0840	transmembrane signaling receptor activity
FT673_18190	COG2759	Belongs to the formate--tetrahydrofolate ligase family
FT673_18230	COG2195	Cleaves the N-terminal amino acid of tripeptides
FT673_18310	COG0346	lactoylglutathione lyase activity
FT673_18335	COG2807	transmembrane transport
FT673_18345	COG0583	DNA-binding transcription factor activity
FT673_18375	COG2979	Protein of unknown function (DUF533)
FT673_18395	COG1271	oxidase subunit
FT673_18400	COG1294	oxidase, subunit
FT673_18415	COG0656	L-ascorbic acid biosynthetic process
FT673_18440	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
FT673_18445	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
FT673_18450	COG2271	Major facilitator Superfamily
FT673_18475	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
FT673_18480	COG1605	Chorismate mutase
FT673_18480	COG0287	Prephenate dehydrogenase
FT673_18490	COG3085	chromosome segregation
FT673_18495	COG4574	serine-type endopeptidase inhibitor activity
FT673_18535	COG3081	Nucleoid-associated protein
FT673_18545	COG1175	transmembrane transport
FT673_18555	COG3842	ATPase activity
FT673_18580	COG0425	Belongs to the sulfur carrier protein TusA family
FT673_18585	COG4783	chaperone-mediated protein folding
FT673_18595	COG1393	Belongs to the ArsC family
FT673_18610	COG3124	Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP
FT673_18620	COG2431	L-lysine efflux transmembrane transporter activity
FT673_18650	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
FT673_18740	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
FT673_18765	COG0483	inositol monophosphate 1-phosphatase activity
FT673_18775	COG0625	glutathione transferase activity
FT673_18810	COG0404	The glycine cleavage system catalyzes the degradation of glycine
FT673_18815	COG0509	glycine decarboxylation via glycine cleavage system
FT673_18820	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
FT673_18820	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
FT673_18825	COG0640	Transcriptional regulator
FT673_18835	COG1393	Belongs to the ArsC family
FT673_18865	COG0517	IMP dehydrogenase activity
FT673_18880	COG1862	Preprotein translocase
FT673_18890	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FT673_18915	COG3154	lipid carrier protein
FT673_18935	COG1104	cysteine desulfurase activity
FT673_18940	COG0822	iron-sulfur transferase activity
FT673_18950	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
FT673_18960	COG0633	Ferredoxin
FT673_19005	COG2976	Protein conserved in bacteria
FT673_19020	COG1645	bacterial-type flagellum-dependent swarming motility
FT673_19030	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
FT673_19035	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
FT673_19035	COG0047	phosphoribosylformylglycinamidine synthase activity
FT673_19070	COG0713	ATP synthesis coupled electron transport
FT673_19075	COG0839	Belongs to the complex I subunit 6 family
FT673_19080	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FT673_19105	COG0649	NAD binding
FT673_19105	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FT673_19115	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FT673_19120	COG1360	Flagellar Motor Protein
FT673_19165	COG0724	RNA recognition motif
FT673_19170	COG4989	oxidoreductase activity
FT673_19195	COG3437	response regulator, receiver
FT673_19200	COG0583	DNA-binding transcription factor activity
FT673_19210	COG3300	MHYT domain
FT673_19210	COG5001	Diguanylate cyclase
FT673_19215	COG0778	Nitroreductase
FT673_19245	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FT673_19300	COG3530	Putative quorum-sensing-regulated virulence factor
FT673_19310	COG2916	Histone family protein nucleoid-structuring protein H-NS
FT673_19320	COG1435	thymidine kinase activity
FT673_19340	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
FT673_19400	COG2003	Belongs to the UPF0758 family
FT673_19445	COG3311	Transcriptional regulator
FT673_19485	COG0582	viral genome integration into host DNA
FT673_19510	COG3209	COG3209 Rhs family protein
FT673_19715	COG2916	Histone family protein nucleoid-structuring protein H-NS
FT673_19725	COG5642	Protein of unknown function (DUF2384)
FT673_19750	COG3447	MASE1 domain protein
FT673_19750	COG5001	Diguanylate cyclase
FT673_19750	COG5002	protein histidine kinase activity
FT673_19850	COG1278	Cold shock
FT673_19865	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
FT673_19870	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
FT673_19875	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
FT673_19880	COG3134	Outer membrane lipoprotein
FT673_19890	COG0492	ferredoxin-NADP+ reductase activity
FT673_19910	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
FT673_19915	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
FT673_19925	COG1286	toxin biosynthetic process
FT673_19930	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
FT673_19940	COG4172	Belongs to the ABC transporter superfamily
FT673_19950	COG4171	peptide transport system, permease
FT673_19955	COG4168	peptide transport system, permease
FT673_20000	COG2154	pterin-4-alpha-carbinolamine dehydratase
FT673_20120	COG0257	Belongs to the bacterial ribosomal protein bL36 family
FT673_20140	COG1451	nucleotide metabolic process
FT673_20170	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FT673_20195	COG1053	succinate dehydrogenase
FT673_20215	COG0045	succinate-CoA ligase (ADP-forming) activity
FT673_20230	COG2983	Belongs to the UPF0260 family
FT673_20250	COG1840	ABC-type Fe3 transport system, periplasmic component
FT673_20270	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FT673_20295	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
FT673_20315	COG2910	NAD(P)H-binding
FT673_20400	COG1051	belongs to the nudix hydrolase family
FT673_20405	COG3088	subunit of a heme lyase
FT673_20405	COG4235	cytochrome complex assembly
FT673_20410	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FT673_20420	COG3301	Polysulphide reductase, NrfD
FT673_20425	COG0437	4 iron, 4 sulfur cluster binding
FT673_20430	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
FT673_20465	COG3012	SEC-C Motif Domain Protein
FT673_20535	COG0586	Pfam SNARE associated Golgi protein
FT673_20540	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
FT673_20550	COG3067	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
FT673_20555	COG2186	Transcriptional regulator
FT673_20560	COG2719	SpoVR family
FT673_20575	COG0514	ATP-dependent DNA helicase (RecQ)
FT673_20630	COG3118	belongs to the thioredoxin family
FT673_20640	COG1132	(ABC) transporter
FT673_20695	COG2329	Antibiotic biosynthesis monooxygenase
FT673_20725	COG1742	UPF0060 membrane protein
FT673_20735	COG0456	acetyltransferase
FT673_20740	COG0513	Belongs to the DEAD box helicase family
FT673_20745	COG0386	Belongs to the glutathione peroxidase family
FT673_20760	COG1181	Belongs to the D-alanine--D-alanine ligase family
FT673_20850	COG1011	Hydrolase
FT673_20855	COG1473	amidohydrolase
FT673_20860	COG0205	6-phosphofructokinase activity
FT673_20885	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
FT673_20910	COG0242	peptide deformylase activity
FT673_20955	COG2824	Alkylphosphonate utilization operon protein PhnA
FT673_20990	COG3706	GGDEF domain
FT673_21000	COG2840	Smr protein MutS2
FT673_21005	COG2890	protein-(glutamine-N5) methyltransferase activity
FT673_21010	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
FT673_21020	COG0513	Belongs to the DEAD box helicase family
FT673_21025	COG5654	RES domain protein
FT673_21035	COG0814	amino acid
FT673_21040	COG1609	Transcriptional regulator
FT673_21060	COG2140	Oxalate decarboxylase
FT673_21080	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
FT673_21080	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FT673_21090	COG3716	PTS system mannose fructose sorbose family IID component
FT673_21095	COG2942	2-epimerase
FT673_21100	COG3313	Fe-S protein
FT673_21110	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
FT673_21115	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FT673_21120	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FT673_21130	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
FT673_21160	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
FT673_21165	COG0291	Belongs to the bacterial ribosomal protein bL35 family
FT673_21170	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
FT673_21405	COG4974	Belongs to the 'phage' integrase family
FT673_21410	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
FT673_21420	COG0776	regulation of translation
FT673_21460	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FT673_21465	COG1879	ABC-type sugar transport system periplasmic component
FT673_21470	COG1172	Belongs to the binding-protein-dependent transport system permease family
FT673_21480	COG1869	D-ribose catabolic process
FT673_21505	COG0589	response to stress
FT673_21590	COG0167	dihydroorotate dehydrogenase activity
FT673_21600	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
FT673_21600	COG0116	Belongs to the methyltransferase superfamily
FT673_21625	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
FT673_21630	COG1067	ATP-dependent peptidase activity
FT673_21640	COG3141	response to X-ray
FT673_21695	COG0372	Belongs to the citrate synthase family
FT673_21700	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
FT673_21710	COG2995	paraquat-inducible protein a
FT673_21745	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
FT673_21750	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
FT673_21755	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FT673_21765	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FT673_21770	COG1028	Short-chain dehydrogenase reductase Sdr
FT673_21780	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FT673_21785	COG0416	fatty acid biosynthetic process
FT673_21790	COG0333	Belongs to the bacterial ribosomal protein bL32 family
FT673_21795	COG1399	metal-binding, possibly nucleic acid-binding protein
FT673_21825	COG0564	pseudouridine synthase activity
FT673_21830	COG1530	ribonuclease E activity
FT673_21850	COG0572	uridine kinase
FT673_21860	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FT673_21860	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FT673_21870	COG1254	Belongs to the acylphosphatase family
FT673_21880	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
FT673_21895	COG0709	Synthesizes selenophosphate from selenide and ATP
FT673_21905	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FT673_21920	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
FT673_21935	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
FT673_21935	COG0617	tRNA 3'-terminal CCA addition
FT673_21935	COG0517	IMP dehydrogenase activity
FT673_21965	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
FT673_21970	COG2832	Protein of unknown function (DUF454)
FT673_21975	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
FT673_22000	COG2226	methyltransferase
FT673_22000	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
FT673_22000	COG0596	Alpha beta hydrolase
FT673_22010	COG1214	PFAM Peptidase M22, glycoprotease
FT673_22050	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
FT673_22060	COG3437	response regulator, receiver
FT673_22075	COG0107	imidazoleglycerol-phosphate synthase activity
FT673_22125	COG2252	PERMEase
FT673_22130	COG0402	S-adenosylhomocysteine deaminase activity
FT673_22145	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
FT673_22150	COG0402	S-adenosylhomocysteine deaminase activity
FT673_22175	COG0697	spore germination
FT673_22265	COG4397	Mu-like prophage major head subunit gpT
FT673_22290	COG4373	Mu-like prophage FluMu protein gp28
FT673_22490	COG2067	long-chain fatty acid transport protein
FT673_22495	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
FT673_22515	COG3123	guanosine phosphorylase activity
FT673_22520	COG1760	l-serine dehydratase
FT673_22530	COG1760	l-serine dehydratase
FT673_22540	COG3100	YcgL domain-containing protein
FT673_22545	COG0850	regulation of cytokinetic process
FT673_22550	COG2894	cell division
FT673_22555	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
FT673_22560	COG3099	Belongs to the UPF0263 family
FT673_22565	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FT673_22610	COG0697	spore germination
FT673_22620	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FT673_22640	COG0534	Mate efflux family protein
FT673_22695	COG1560	Kdo2-lipid A biosynthetic process
FT673_22700	COG1560	Kdo2-lipid A biosynthetic process
FT673_22710	COG0583	DNA-binding transcription factor activity
FT673_22780	COG0730	response to heat
FT673_22810	COG1960	acyl-CoA dehydrogenase activity
FT673_22860	COG1584	GPR1 FUN34 yaaH family protein
FT673_22875	COG1115	amino acid carrier protein
FT673_22915	COG1024	Enoyl-CoA hydratase
FT673_22930	COG3162	membrane
FT673_22935	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FT673_22940	COG0488	(ABC) transporter
FT673_22970	COG0544	peptidyl-prolyl cis-trans isomerase activity
FT673_22985	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
FT673_22995	COG1136	(ABC) transporter
FT673_23010	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
FT673_23015	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
FT673_23020	COG4166	transmembrane transport
FT673_23060	COG2169	Transcriptional regulator
FT673_23060	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
FT673_23130	COG3657	addiction module killer protein
FT673_23135	COG3636	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
FT673_23155	COG0582	viral genome integration into host DNA
FT673_23290	COG1120	ATPase activity
FT673_23315	COG1028	Short-chain dehydrogenase reductase Sdr
FT673_23370	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FT673_23375	COG3788	relative of glutathione S-transferase, MAPEG superfamily
FT673_23380	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
FT673_23385	COG0563	adenylate kinase activity
FT673_23395	COG0326	Molecular chaperone. Has ATPase activity
FT673_23405	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
FT673_23450	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
FT673_23455	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
FT673_23515	COG0298	carbon dioxide binding
FT673_23525	COG0309	Hydrogenase expression formation protein (HypE)
FT673_23535	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
FT673_23540	COG3842	ATPase activity
FT673_23550	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FT673_23565	COG1773	rubredoxin
FT673_23660	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs