locus-tag	class	description
HQ395_00015	COG3031	protein transport across the cell outer membrane
HQ395_00025	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
HQ395_00030	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
HQ395_00050	COG0456	acetyltransferase
HQ395_00055	COG3133	Outer membrane lipoprotein
HQ395_00070	COG2771	luxR family
HQ395_00075	COG3916	Acyl-homoserine-lactone synthase
HQ395_00085	COG4776	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction
HQ395_00090	COG1309	transcriptional regulator
HQ395_00100	COG2213	PTS system mannitol-specific
HQ395_00100	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
HQ395_00105	COG0246	Mannitol dehydrogenase
HQ395_00110	COG3722	fumarate hydratase activity
HQ395_00115	COG3263	regulation of cellular component size
HQ395_00140	COG1671	Belongs to the UPF0178 family
HQ395_00155	COG1988	membrane-bound metal-dependent
HQ395_00160	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
HQ395_00165	COG0513	Belongs to the DEAD box helicase family
HQ395_00190	COG1575	Belongs to the MenA family. Type 1 subfamily
HQ395_00195	COG1169	isochorismate synthase
HQ395_00200	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
HQ395_00205	COG0596	Alpha beta hydrolase
HQ395_00210	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
HQ395_00215	COG1441	menaquinone biosynthetic process
HQ395_00220	COG0318	PFAM AMP-dependent synthetase and ligase
HQ395_00235	COG3539	Fimbrial protein
HQ395_00240	COG3121	Chaperone
HQ395_00245	COG3188	usher protein
HQ395_00255	COG3539	Fimbrial protein
HQ395_00265	COG3291	Pkd domain containing protein
HQ395_00270	COG2949	membrane
HQ395_00275	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
HQ395_00285	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
HQ395_00290	COG5380	lipid catabolic process
HQ395_00305	COG4533	DNA binding
HQ395_00315	COG2873	o-acetylhomoserine
HQ395_00325	COG1979	alcohol dehydrogenase
HQ395_00345	COG4221	oxidoreductase activity
HQ395_00365	COG1285	pathogenesis
HQ395_00385	COG1368	sulfuric ester hydrolase activity
HQ395_00390	COG1522	sequence-specific DNA binding
HQ395_00400	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
HQ395_00405	COG1418	mRNA catabolic process
HQ395_00410	COG1546	Belongs to the CinA family
HQ395_00410	COG1058	Belongs to the CinA family
HQ395_00420	COG1129	ABC transporter
HQ395_00420	COG0842	Transport permease protein
HQ395_00435	COG0561	phosphatase activity
HQ395_00440	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
HQ395_00460	COG1011	Hydrolase
HQ395_00475	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
HQ395_00480	COG0019	diaminopimelate decarboxylase activity
HQ395_00490	COG1965	Belongs to the frataxin family
HQ395_00495	COG0400	carboxylic ester hydrolase activity
HQ395_00500	COG3072	Adenylate cyclase
HQ395_00505	COG0181	hydroxymethylbilane synthase activity
HQ395_00515	COG2959	enzyme of heme biosynthesis
HQ395_00530	COG1494	fructose-1,6-bisphosphatase
HQ395_00570	COG1733	regulation of RNA biosynthetic process
HQ395_00590	COG3932	Exopolysaccharide synthesis, ExoD
HQ395_00595	COG0814	amino acid
HQ395_00600	COG5433	transposase activity
HQ395_00605	COG3706	GGDEF domain
HQ395_00620	COG3417	Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1B (PBP1b)
HQ395_00635	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
HQ395_00640	COG2022	thiamine diphosphate biosynthetic process
HQ395_00650	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
HQ395_00655	COG0352	thiamine-phosphate diphosphorylase activity
HQ395_00660	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
HQ395_00680	COG0745	RESPONSE REGULATOR receiver
HQ395_00685	COG0642	Histidine kinase
HQ395_00695	COG0189	ligase activity
HQ395_00720	COG1639	'signal transduction protein
HQ395_00730	COG2321	neutral zinc metallopeptidase
HQ395_00735	COG3700	Belongs to the class B bacterial acid phosphatase family
HQ395_00760	COG1366	Belongs to the anti-sigma-factor antagonist family
HQ395_00765	COG2172	sigma factor antagonist activity
HQ395_00775	COG3437	response regulator, receiver
HQ395_00785	COG0477	Major facilitator Superfamily
HQ395_00800	COG0312	modulator of DNA gyrase
HQ395_00805	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
HQ395_00820	COG3164	Protein of unknown function
HQ395_00825	COG1530	ribonuclease E activity
HQ395_00830	COG0424	maF-like protein
HQ395_00835	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
HQ395_00840	COG1792	Involved in formation and maintenance of cell shape
HQ395_00845	COG1077	Cell shape determining protein MreB Mrl
HQ395_00870	COG4968	Prepilin-type N-terminal cleavage methylation domain
HQ395_00880	COG2165	general secretion pathway protein
HQ395_00890	COG1459	type II secretion system
HQ395_00895	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
HQ395_00905	COG2842	Transposition protein
HQ395_00940	COG2199	diguanylate cyclase activity
HQ395_00940	COG2200	EAL domain
HQ395_00945	COG2200	EAL domain
HQ395_00950	COG0387	Pfam Sodium calcium exchanger
HQ395_00955	COG2986	histidine ammonia-lyase
HQ395_00960	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
HQ395_00965	COG0010	Belongs to the arginase family
HQ395_00970	COG1228	amidohydrolase
HQ395_00975	COG2188	Transcriptional regulator
HQ395_00980	COG0288	reversible hydration of carbon dioxide
HQ395_00990	COG2177	Part of the ABC transporter FtsEX involved in
HQ395_00995	COG2884	Cell division ATP-binding protein ftsE
HQ395_01000	COG0552	protein localization to endoplasmic reticulum
HQ395_01005	COG0742	ribosomal rna small subunit methyltransferase
HQ395_01030	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HQ395_01040	COG0741	lytic transglycosylase activity
HQ395_01050	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
HQ395_01060	COG2095	MarC family integral membrane protein
HQ395_01070	COG1301	dicarboxylic acid transport
HQ395_01095	COG3714	YhhN family
HQ395_01115	COG1770	oligopeptidase
HQ395_01130	COG4221	oxidoreductase activity
HQ395_01135	COG0583	DNA-binding transcription factor activity
HQ395_01140	COG2249	NAD(P)H dehydrogenase (quinone) activity
HQ395_01160	COG1484	DNA-dependent DNA replication
HQ395_01165	COG4584	PFAM Integrase catalytic
HQ395_01200	COG0203	ribosomal protein L17
HQ395_01205	COG0202	RNA polymerase activity
HQ395_01210	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
HQ395_01215	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
HQ395_01220	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
HQ395_01225	COG0257	Belongs to the bacterial ribosomal protein bL36 family
HQ395_01230	COG0201	protein transport
HQ395_01235	COG0200	Binds to the 23S rRNA
HQ395_01240	COG1841	ribosomal large subunit assembly
HQ395_01245	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
HQ395_01250	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
HQ395_01255	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
HQ395_01260	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
HQ395_01265	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
HQ395_01270	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
HQ395_01275	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
HQ395_01280	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
HQ395_01285	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
HQ395_01290	COG0255	Belongs to the universal ribosomal protein uL29 family
HQ395_01295	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
HQ395_01300	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
HQ395_01305	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
HQ395_01310	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
HQ395_01315	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
HQ395_01320	COG0089	rRNA binding
HQ395_01325	COG0088	Forms part of the polypeptide exit tunnel
HQ395_01330	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
HQ395_01335	COG0051	transcription antitermination factor activity, RNA binding
HQ395_01355	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
HQ395_01360	COG2183	response to ionizing radiation
HQ395_01380	COG0596	Alpha beta hydrolase
HQ395_01385	COG1040	competence protein
HQ395_01390	COG0316	Belongs to the HesB IscA family
HQ395_01390	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
HQ395_01400	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
HQ395_01405	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
HQ395_01410	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HQ395_01415	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
HQ395_01420	COG4942	peptidase
HQ395_01430	COG1609	Transcriptional regulator
HQ395_01435	COG0800	Aldolase
HQ395_01445	COG3265	gluconokinase activity
HQ395_01450	COG2610	gluconate transmembrane transporter activity
HQ395_01455	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HQ395_01460	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
HQ395_01470	COG0456	acetyltransferase
HQ395_01480	COG1490	D-aminoacyl-tRNA deacylase activity
HQ395_01485	COG1295	ribonuclease BN
HQ395_01490	COG1217	gtp-binding protein TYPA
HQ395_01495	COG0174	glutamine synthetase
HQ395_01505	COG3852	Histidine kinase
HQ395_01510	COG2204	response regulator
HQ395_01515	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
HQ395_01520	COG0635	Involved in the biosynthesis of porphyrin-containing compound
HQ395_01530	COG3078	GTPase activator activity
HQ395_01535	COG5433	transposase activity
HQ395_01550	COG0218	Necessary for normal cell division and for the maintenance of normal septation
HQ395_01560	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
HQ395_01565	COG0408	coproporphyrinogen oxidase activity
HQ395_01570	COG0009	L-threonylcarbamoyladenylate synthase
HQ395_01580	COG0551	DNA topoisomerase type I activity
HQ395_01585	COG2922	Belongs to the Smg family
HQ395_01600	COG0242	peptide deformylase activity
HQ395_01605	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
HQ395_01610	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
HQ395_01610	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
HQ395_01615	COG0569	domain protein
HQ395_01620	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
HQ395_01625	COG1322	Protein conserved in bacteria
HQ395_01645	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HQ395_01650	COG0686	Belongs to the AlaDH PNT family
HQ395_01655	COG0518	GMP synthase (glutamine-hydrolyzing) activity
HQ395_01655	COG0519	Catalyzes the synthesis of GMP from XMP
HQ395_01665	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
HQ395_01670	COG1396	sequence-specific DNA binding
HQ395_01675	COG1012	belongs to the aldehyde dehydrogenase family
HQ395_01685	COG2962	Rard protein
HQ395_01695	COG1280	lysine exporter protein (LysE YggA)
HQ395_01705	COG2391	methyltransferase activity
HQ395_01710	COG1280	lysine exporter protein (LysE YggA)
HQ395_01760	COG0583	DNA-binding transcription factor activity
HQ395_01765	COG1943	Transposase
HQ395_01775	COG0210	DNA helicase
HQ395_01780	COG1744	ABC transporter substrate-binding protein PnrA-like
HQ395_01785	COG3845	ABC transporter
HQ395_01790	COG4603	Belongs to the binding-protein-dependent transport system permease family
HQ395_01795	COG1079	Belongs to the binding-protein-dependent transport system permease family
HQ395_01800	COG0583	DNA-binding transcription factor activity
HQ395_01820	COG1262	PFAM Formylglycine-generating sulfatase enzyme
HQ395_01825	COG0385	Bile acid
HQ395_01835	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HQ395_01840	COG0531	amino acid
HQ395_01845	COG2731	YhcH YjgK YiaL family protein
HQ395_01850	COG3250	beta-galactosidase activity
HQ395_01855	COG1609	Transcriptional regulator
HQ395_01890	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
HQ395_01895	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HQ395_01895	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HQ395_01900	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
HQ395_01905	COG3074	FtsZ-dependent cytokinesis
HQ395_01915	COG1045	serine acetyltransferase
HQ395_01925	COG0745	RESPONSE REGULATOR receiver
HQ395_01930	COG2205	protein histidine kinase activity
HQ395_01935	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
HQ395_01940	COG0534	Mate efflux family protein
HQ395_01955	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
HQ395_01960	COG2937	Belongs to the GPAT DAPAT family
HQ395_01965	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
HQ395_01970	COG3161	chorismate lyase activity
HQ395_01990	COG0604	alcohol dehydrogenase
HQ395_01995	COG1609	Transcriptional regulator
HQ395_02015	COG1519	Transferase
HQ395_02020	COG0859	PFAM glycosyl transferase family 9
HQ395_02025	COG0463	Glycosyl transferase, family 2
HQ395_02030	COG0859	PFAM glycosyl transferase family 9
HQ395_02035	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
HQ395_02040	COG2990	Protein conserved in bacteria
HQ395_02045	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
HQ395_02055	COG0267	Belongs to the bacterial ribosomal protein bL33 family
HQ395_02060	COG0227	Belongs to the bacterial ribosomal protein bL28 family
HQ395_02065	COG2003	Belongs to the UPF0758 family
HQ395_02070	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
HQ395_02075	COG0756	dUTP diphosphatase activity
HQ395_02080	COG1309	transcriptional regulator
HQ395_02085	COG0668	transmembrane transport
HQ395_02095	COG0166	Belongs to the GPI family
HQ395_02100	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
HQ395_02105	COG0583	DNA-binding transcription factor activity
HQ395_02145	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
HQ395_02155	COG1739	Uncharacterized protein family UPF0029
HQ395_02160	COG0006	proline dipeptidase activity
HQ395_02165	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
HQ395_02170	COG1024	Enoyl-CoA hydratase
HQ395_02170	COG1250	3-hydroxyacyl-CoA dehydrogenase
HQ395_02175	COG0183	Belongs to the thiolase family
HQ395_02200	COG0425	Belongs to the sulfur carrier protein TusA family
HQ395_02205	COG0251	oxidation-reduction process
HQ395_02210	COG2885	chlorophyll binding
HQ395_02220	COG2818	Glycosylase
HQ395_02225	COG0752	glycyl-tRNA synthetase alpha subunit
HQ395_02230	COG0751	glycine-tRNA ligase activity
HQ395_02275	COG0814	amino acid
HQ395_02280	COG0348	domain, Protein
HQ395_02290	COG0446	pyridine nucleotide-disulphide oxidoreductase
HQ395_02295	COG0426	domain, Protein
HQ395_02295	COG1773	rubredoxin
HQ395_02300	COG3604	Transcriptional regulator
HQ395_02305	COG1609	Transcriptional regulator
HQ395_02345	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HQ395_02370	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
HQ395_02385	COG3118	belongs to the thioredoxin family
HQ395_02390	COG0513	Belongs to the DEAD box helicase family
HQ395_02395	COG0248	Ppx GppA phosphatase
HQ395_02410	COG0742	ribosomal rna small subunit methyltransferase
HQ395_02430	COG0084	hydrolase, TatD family'
HQ395_02435	COG0805	protein transport
HQ395_02440	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
HQ395_02450	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
HQ395_02455	COG3165	ubiquinone biosynthetic process from chorismate
HQ395_02465	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HQ395_02470	COG0402	S-adenosylhomocysteine deaminase activity
HQ395_02515	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
HQ395_02520	COG0848	biopolymer transport protein
HQ395_02525	COG0811	peptide transport
HQ395_02530	COG0811	peptide transport
HQ395_02540	COG2771	luxR family
HQ395_02545	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
HQ395_02550	COG1349	DNA-binding transcription factor activity
HQ395_02555	COG0745	RESPONSE REGULATOR receiver
HQ395_02560	COG2205	protein histidine kinase activity
HQ395_02570	COG4452	Inner membrane protein CreD
HQ395_02575	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
HQ395_02580	COG0355	proton-transporting ATP synthase activity, rotational mechanism
HQ395_02585	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
HQ395_02590	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
HQ395_02595	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
HQ395_02600	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HQ395_02605	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
HQ395_02615	COG0356	it plays a direct role in the translocation of protons across the membrane
HQ395_02625	COG1475	DNA binding
HQ395_02630	COG1192	Involved in chromosome partitioning
HQ395_02635	COG0357	Ribosomal RNA small subunit methyltransferase G
HQ395_02640	COG0445	tRNA wobble uridine modification
HQ395_02645	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
HQ395_02650	COG4774	siderophore transport
HQ395_02655	COG4615	Cyclic peptide transporter
HQ395_02660	COG1120	ATPase activity
HQ395_02665	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
HQ395_02680	COG0706	membrane insertase activity
HQ395_02685	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
HQ395_02690	COG0594	ribonuclease P activity
HQ395_02695	COG0230	Belongs to the bacterial ribosomal protein bL34 family
HQ395_02700	COG1126	abc transporter atp-binding protein
HQ395_02715	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
HQ395_02720	COG0592	DNA-directed DNA polymerase activity
HQ395_02725	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
HQ395_02740	COG2378	regulation of single-species biofilm formation
HQ395_02745	COG0071	Belongs to the small heat shock protein (HSP20) family
HQ395_02750	COG0071	Belongs to the small heat shock protein (HSP20) family
HQ395_02755	COG3977	Valine--pyruvate aminotransferase
HQ395_02770	COG2814	Major facilitator Superfamily
HQ395_02775	COG0745	RESPONSE REGULATOR receiver
HQ395_02780	COG2205	protein histidine kinase activity
HQ395_02800	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
HQ395_02805	COG4191	Histidine kinase
HQ395_02805	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HQ395_02810	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HQ395_02815	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HQ395_02820	COG1309	transcriptional regulator
HQ395_02850	COG0561	phosphatase activity
HQ395_02855	COG2267	carboxylic ester hydrolase activity
HQ395_02865	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HQ395_02870	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HQ395_02875	COG1758	RNA polymerase activity
HQ395_02885	COG0859	PFAM glycosyl transferase family 9
HQ395_02890	COG3642	lipopolysaccharide core region biosynthetic process
HQ395_02930	COG0589	response to stress
HQ395_02935	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
HQ395_02945	COG1528	Iron-storage protein
HQ395_02950	COG2081	HI0933 family
HQ395_02955	COG2223	nitrite transmembrane transporter activity
HQ395_02965	COG3275	phosphorelay sensor kinase activity
HQ395_02970	COG3279	Response regulator of the LytR AlgR family
HQ395_02975	COG2223	nitrite transmembrane transporter activity
HQ395_02980	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
HQ395_02985	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
HQ395_03000	COG0583	DNA-binding transcription factor activity
HQ395_03005	COG4206	TonB-dependent receptor
HQ395_03010	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
HQ395_03045	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
HQ395_03050	COG2166	iron-sulfur cluster assembly
HQ395_03055	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
HQ395_03060	COG0210	DNA helicase
HQ395_03070	COG3245	cytochrome
HQ395_03075	COG1063	alcohol dehydrogenase
HQ395_03080	COG0156	8-amino-7-oxononanoate synthase activity
HQ395_03090	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
HQ395_03105	COG3306	glycosyltransferase involved in LPS biosynthesis
HQ395_03125	COG1561	YicC-like family, N-terminal region
HQ395_03130	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
HQ395_03135	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
HQ395_03145	COG0789	Transcriptional regulator
HQ395_03150	COG4251	negative regulation of phosphorylation
HQ395_03150	COG2203	Gaf domain
HQ395_03150	COG5001	Diguanylate cyclase
HQ395_03150	COG3706	GGDEF domain
HQ395_03155	COG3084	Protein conserved in bacteria
HQ395_03165	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
HQ395_03170	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
HQ395_03180	COG1335	isochorismatase
HQ395_03190	COG1683	Conserved Protein
HQ395_03195	COG0204	Acyl-transferase
HQ395_03200	COG0204	Acyl-transferase
HQ395_03205	COG0606	chelatase, subunit chli
HQ395_03215	COG3978	acetolactate synthase activity
HQ395_03225	COG0129	dihydroxy-acid dehydratase activity
HQ395_03245	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
HQ395_03250	COG0254	rRNA binding
HQ395_03255	COG0702	epimerase
HQ395_03260	COG0281	malic enzyme
HQ395_03270	COG2205	protein histidine kinase activity
HQ395_03275	COG0745	RESPONSE REGULATOR receiver
HQ395_03280	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HQ395_03295	COG0366	Alpha amylase catalytic
HQ395_03310	COG0443	Heat shock 70 kDa protein
HQ395_03315	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HQ395_03320	COG3045	CreA protein
HQ395_03340	COG0174	glutamine synthetase
HQ395_03360	COG3842	ATPase activity
HQ395_03365	COG1176	ABC-type spermidine putrescine transport system, permease component I
HQ395_03370	COG1177	transmembrane transport
HQ395_03375	COG2258	MOSC domain
HQ395_03395	COG2050	protein possibly involved in aromatic compounds catabolism
HQ395_03400	COG0514	ATP-dependent DNA helicase (RecQ)
HQ395_03410	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
HQ395_03420	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
HQ395_03425	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
HQ395_03435	COG2239	Acts as a magnesium transporter
HQ395_03440	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
HQ395_03440	COG1648	precorrin-2 dehydrogenase activity
HQ395_03445	COG2116	formate transmembrane transporter activity
HQ395_03455	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
HQ395_03460	COG0842	Transport permease protein
HQ395_03465	COG0842	Transport permease protein
HQ395_03470	COG1131	(ABC) transporter
HQ395_03475	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HQ395_03495	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
HQ395_03500	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
HQ395_03520	COG1595	DNA-templated transcription, initiation
HQ395_03525	COG3806	Anti-sigma factor
HQ395_03530	COG1968	undecaprenyl-diphosphatase activity
HQ395_03535	COG0667	Aldo Keto reductase
HQ395_03540	COG2017	converts alpha-aldose to the beta-anomer
HQ395_03545	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
HQ395_03555	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
HQ395_03560	COG1609	Transcriptional regulator
HQ395_03565	COG3250	beta-galactosidase activity
HQ395_03585	COG0840	transmembrane signaling receptor activity
HQ395_03615	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
HQ395_03620	COG1288	antiporter activity
HQ395_03625	COG1438	arginine binding
HQ395_03630	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
HQ395_03635	COG0540	Belongs to the ATCase OTCase family
HQ395_03655	COG0688	phosphatidylethanolamine metabolic process
HQ395_03670	COG3040	lipid binding
HQ395_03675	COG2207	Transcriptional regulator
HQ395_03680	COG1979	alcohol dehydrogenase
HQ395_03685	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
HQ395_03690	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
HQ395_03700	COG3681	Belongs to the UPF0597 family
HQ395_03710	COG0446	pyridine nucleotide-disulphide oxidoreductase
HQ395_03715	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
HQ395_03720	COG0564	pseudouridine synthase activity
HQ395_03730	COG0542	response to heat
HQ395_03740	COG2502	aspartate--ammonia ligase
HQ395_03745	COG1522	sequence-specific DNA binding
HQ395_03755	COG5413	integral membrane protein
HQ395_03780	COG2205	protein histidine kinase activity
HQ395_03790	COG2204	response regulator
HQ395_03805	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
HQ395_03835	COG0243	molybdopterin cofactor binding
HQ395_03840	COG3005	denitrification pathway
HQ395_03845	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HQ395_03865	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
HQ395_03870	COG0569	domain protein
HQ395_03875	COG0812	UDP-N-acetylmuramate dehydrogenase activity
HQ395_03900	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
HQ395_03915	COG0250	Participates in transcription elongation, termination and antitermination
HQ395_03920	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
HQ395_03925	COG0081	regulation of translation
HQ395_03930	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
HQ395_03935	COG0222	ribosome binding
HQ395_03940	COG0085	RNA polymerase activity
HQ395_03945	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HQ395_03950	COG2964	Protein conserved in bacteria
HQ395_03955	COG0251	oxidation-reduction process
HQ395_03965	COG2923	Belongs to the DsrF TusC family
HQ395_03970	COG2168	tRNA wobble position uridine thiolation
HQ395_03975	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
HQ395_03980	COG0049	tRNA binding
HQ395_03985	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
HQ395_03990	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
HQ395_03995	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
HQ395_04035	COG2252	PERMEase
HQ395_04040	COG2376	Dihydroxyacetone kinase
HQ395_04045	COG1461	Dihydroxyacetone kinase
HQ395_04060	COG3284	Transcriptional regulator
HQ395_04070	COG2957	Belongs to the agmatine deiminase family
HQ395_04080	COG0628	permease
HQ395_04085	COG0494	nUDIX hydrolase
HQ395_04110	COG0753	catalase activity
HQ395_04115	COG1247	-acetyltransferase
HQ395_04135	COG2199	diguanylate cyclase activity
HQ395_04135	COG2203	Gaf domain
HQ395_04155	COG1176	ABC-type spermidine putrescine transport system, permease component I
HQ395_04180	COG0583	DNA-binding transcription factor activity
HQ395_04190	COG1741	Belongs to the pirin family
HQ395_04195	COG2259	Doxx family
HQ395_04200	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
HQ395_04205	COG1074	ATP-dependent DNA helicase activity
HQ395_04210	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
HQ395_04220	COG0346	lactoylglutathione lyase activity
HQ395_04270	COG3706	GGDEF domain
HQ395_04275	COG4771	TonB-dependent receptor
HQ395_04280	COG1278	Cold shock
HQ395_04300	COG0629	single-stranded DNA binding
HQ395_04305	COG2197	response regulator
HQ395_04310	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
HQ395_04320	COG3047	cAMP biosynthetic process
HQ395_04325	COG0840	transmembrane signaling receptor activity
HQ395_04350	COG3135	benzoate transporter
HQ395_04355	COG1396	sequence-specific DNA binding
HQ395_04385	COG2926	Belongs to the UPF0265 family
HQ395_04395	COG3028	Belongs to the UPF0307 family
HQ395_04400	COG0312	modulator of DNA gyrase
HQ395_04405	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HQ395_04410	COG5007	Belongs to the BolA IbaG family
HQ395_04420	COG2854	intermembrane phospholipid transfer
HQ395_04425	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
HQ395_04430	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
HQ395_04435	COG1127	ABC transporter
HQ395_04440	COG0517	IMP dehydrogenase activity
HQ395_04440	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
HQ395_04445	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
HQ395_04450	COG3117	lipopolysaccharide transmembrane transporter activity
HQ395_04455	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
HQ395_04460	COG1137	ATPase activity
HQ395_04465	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
HQ395_04475	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
HQ395_04480	COG1660	Displays ATPase and GTPase activities
HQ395_04485	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
HQ395_04490	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
HQ395_04490	COG3711	transcriptional antiterminator
HQ395_04505	COG3964	amidohydrolase
HQ395_04535	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HQ395_04540	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HQ395_04550	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
HQ395_04555	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
HQ395_04560	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
HQ395_04565	COG0723	plastoquinol--plastocyanin reductase activity
HQ395_04570	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
HQ395_04575	COG2857	Cytochrome c1
HQ395_04580	COG0625	glutathione transferase activity
HQ395_04585	COG2969	positive regulation of protein catabolic process
HQ395_04590	COG2823	Periplasmic or secreted lipoprotein
HQ395_04595	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
HQ395_04600	COG0792	nuclease activity
HQ395_04605	COG3107	peptidoglycan biosynthetic process
HQ395_04610	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
HQ395_04660	COG1677	Flagellar hook-basal body complex protein FliE
HQ395_04670	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
HQ395_04705	COG1815	bacterial-type flagellum-dependent cell motility
HQ395_04720	COG1749	Flagellar hook protein flgE
HQ395_04730	COG4786	Flagellar basal body rod
HQ395_04735	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
HQ395_04740	COG1706	bacterial-type flagellum-dependent cell motility
HQ395_04750	COG1256	bacterial-type flagellum assembly
HQ395_04750	COG4786	Flagellar basal body rod
HQ395_04755	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
HQ395_04770	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
HQ395_04775	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
HQ395_04780	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
HQ395_04805	COG1191	sigma factor activity
HQ395_04810	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
HQ395_04815	COG1360	Flagellar Motor Protein
HQ395_04825	COG0741	lytic transglycosylase activity
HQ395_04825	COG1388	LysM domain
HQ395_04835	COG2001	Belongs to the MraZ family
HQ395_04840	COG0275	rRNA processing
HQ395_04845	COG3116	cell division
HQ395_04850	COG0768	penicillin binding
HQ395_04860	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
HQ395_04865	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
HQ395_04870	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
HQ395_04875	COG0772	Belongs to the SEDS family
HQ395_04880	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
HQ395_04885	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
HQ395_04890	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
HQ395_04895	COG0849	cell division
HQ395_04900	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
HQ395_04905	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
HQ395_04915	COG0653	protein targeting
HQ395_04925	COG0494	nUDIX hydrolase
HQ395_04930	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
HQ395_04935	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
HQ395_04950	COG1459	type II secretion system
HQ395_04955	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
HQ395_04980	COG2186	Transcriptional regulator
HQ395_04985	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
HQ395_04990	COG0508	dehydrogenase complex catalyzes the overall conversion of
HQ395_04995	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
HQ395_05005	COG0840	transmembrane signaling receptor activity
HQ395_05010	COG0840	transmembrane signaling receptor activity
HQ395_05015	COG1752	Esterase of the alpha-beta hydrolase superfamily
HQ395_05020	COG1049	propionate catabolic process, 2-methylcitrate cycle
HQ395_05025	COG2200	EAL domain
HQ395_05035	COG1280	lysine exporter protein (LysE YggA)
HQ395_05045	COG0523	cobalamin synthesis protein
HQ395_05050	COG0477	Major facilitator Superfamily
HQ395_05065	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
HQ395_05070	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
HQ395_05110	COG3314	Sporulation integral membrane protein YlbJ
HQ395_05115	COG0784	Response regulator, receiver
HQ395_05115	COG0835	chemotaxis
HQ395_05125	COG1444	tRNA N-acetyltransferase activity
HQ395_05150	COG1803	Methylglyoxal synthase
HQ395_05165	COG0252	asparaginase activity
HQ395_05185	COG1263	PTS System
HQ395_05185	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HQ395_05190	COG0366	Alpha amylase catalytic
HQ395_05195	COG0110	maltose O-acetyltransferase activity
HQ395_05200	COG1522	sequence-specific DNA binding
HQ395_05205	COG5006	permease, DMT superfamily
HQ395_05215	COG1012	belongs to the aldehyde dehydrogenase family
HQ395_05220	COG1177	transmembrane transport
HQ395_05225	COG1176	ABC-type spermidine putrescine transport system, permease component I
HQ395_05230	COG3842	ATPase activity
HQ395_05235	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
HQ395_05240	COG0583	DNA-binding transcription factor activity
HQ395_05245	COG1757	Na H antiporter
HQ395_05285	COG0297	glycogen (starch) synthase activity
HQ395_05290	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
HQ395_05295	COG2813	Specifically methylates the guanine in position
HQ395_05300	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HQ395_05305	COG4251	negative regulation of phosphorylation
HQ395_05305	COG5001	Diguanylate cyclase
HQ395_05305	COG3706	GGDEF domain
HQ395_05305	COG2203	Gaf domain
HQ395_05315	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
HQ395_05325	COG2995	paraquat-inducible protein a
HQ395_05330	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
HQ395_05330	COG3008	intermembrane lipid transfer
HQ395_05335	COG3009	Protein conserved in bacteria
HQ395_05340	COG2885	chlorophyll binding
HQ395_05340	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
HQ395_05355	COG3111	PFAM Bacterial OB fold (BOF) protein
HQ395_05365	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
HQ395_05370	COG1194	a g-specific adenine glycosylase
HQ395_05380	COG3267	Type II secretory pathway component ExeA
HQ395_05380	COG3409	Peptidoglycan-binding domain 1 protein
HQ395_05385	COG0617	tRNA 3'-terminal CCA addition
HQ395_05400	COG1346	cytolysis
HQ395_05405	COG1380	Effector of murein hydrolase LrgA
HQ395_05410	COG0583	DNA-binding transcription factor activity
HQ395_05440	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
HQ395_05445	COG0306	phosphate transporter
HQ395_05450	COG1392	Phosphate transport regulator
HQ395_05465	COG1560	Kdo2-lipid A biosynthetic process
HQ395_05470	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
HQ395_05470	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
HQ395_05475	COG1538	Outer membrane efflux protein
HQ395_05480	COG0494	nUDIX hydrolase
HQ395_05485	COG3151	Protein conserved in bacteria
HQ395_05495	COG3150	esterase
HQ395_05500	COG1051	belongs to the nudix hydrolase family
HQ395_05515	COG1566	PFAM secretion protein HlyD family protein
HQ395_05520	COG1289	transmembrane transporter activity
HQ395_05570	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
HQ395_05590	COG0204	Acyl-transferase
HQ395_05595	COG1842	Phage shock protein A
HQ395_05610	COG2827	Endonuclease containing a URI domain
HQ395_05620	COG2962	Rard protein
HQ395_05625	COG1573	uracil-dna glycosylase
HQ395_05630	COG0697	spore germination
HQ395_05635	COG0583	DNA-binding transcription factor activity
HQ395_05640	COG1108	ABC-type Mn2 Zn2 transport systems permease components
HQ395_05645	COG1121	(ABC) transporter
HQ395_05650	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
HQ395_05670	COG0739	heme binding
HQ395_05680	COG3068	Protein conserved in bacteria
HQ395_05700	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
HQ395_05740	COG1196	nuclear chromosome segregation
HQ395_05750	COG1546	Belongs to the CinA family
HQ395_05755	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
HQ395_05765	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
HQ395_05775	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
HQ395_05810	COG1686	Belongs to the peptidase S11 family
HQ395_05815	COG0586	Pfam SNARE associated Golgi protein
HQ395_05820	COG1253	flavin adenine dinucleotide binding
HQ395_05825	COG0525	valine-tRNA ligase activity
HQ395_05830	COG2927	DNA polymerase III (CHI subunit)
HQ395_05835	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
HQ395_05840	COG0795	lipopolysaccharide-transporting ATPase activity
HQ395_05845	COG0795	lipopolysaccharide-transporting ATPase activity
HQ395_05860	COG0004	ammonium transporteR
HQ395_05865	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HQ395_05875	COG2165	general secretion pathway protein
HQ395_05880	COG0084	hydrolase, TatD family'
HQ395_05885	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
HQ395_05895	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
HQ395_05900	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
HQ395_05905	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
HQ395_05910	COG0813	purine-nucleoside phosphorylase activity
HQ395_05915	COG3447	MASE1 domain protein
HQ395_05915	COG5002	protein histidine kinase activity
HQ395_05915	COG5001	Diguanylate cyclase
HQ395_05925	COG0560	Phosphoserine phosphatase
HQ395_05950	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
HQ395_05960	COG0776	regulation of translation
HQ395_05975	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HQ395_05980	COG0735	belongs to the Fur family
HQ395_06005	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
HQ395_06010	COG0513	Belongs to the DEAD box helicase family
HQ395_06015	COG3022	response to hydroperoxide
HQ395_06030	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
HQ395_06035	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HQ395_06040	COG0762	integral membrane protein
HQ395_06045	COG1872	DUF167
HQ395_06060	COG4166	transmembrane transport
HQ395_06080	COG1024	Enoyl-CoA hydratase
HQ395_06095	COG4221	oxidoreductase activity
HQ395_06100	COG0442	prolyl-tRNA aminoacylation
HQ395_06105	COG0840	transmembrane signaling receptor activity
HQ395_06110	COG0632	four-way junction helicase activity
HQ395_06115	COG2255	four-way junction helicase activity
HQ395_06120	COG1271	oxidase subunit
HQ395_06125	COG1294	oxidase, subunit
HQ395_06130	COG4890	Cyd operon protein YbgT
HQ395_06135	COG3790	cyd operon protein YbgE
HQ395_06140	COG0824	Thioesterase
HQ395_06145	COG0811	peptide transport
HQ395_06160	COG0823	Involved in the tonB-independent uptake of proteins
HQ395_06165	COG2885	chlorophyll binding
HQ395_06170	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
HQ395_06250	COG0840	transmembrane signaling receptor activity
HQ395_06255	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
HQ395_06260	COG0676	glucose-6-phosphate 1-epimerase activity
HQ395_06265	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
HQ395_06270	COG1640	4-alpha-glucanotransferase
HQ395_06275	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
HQ395_06295	COG1051	belongs to the nudix hydrolase family
HQ395_06300	COG2130	NADP-dependent
HQ395_06305	COG1764	response to oxidative stress
HQ395_06310	COG1846	Transcriptional regulator
HQ395_06345	COG0561	phosphatase activity
HQ395_06360	COG0733	neurotransmitter:sodium symporter activity
HQ395_06370	COG0733	neurotransmitter:sodium symporter activity
HQ395_06395	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HQ395_06410	COG1794	racemase activity, acting on amino acids and derivatives
HQ395_06425	COG2731	YhcH YjgK YiaL family protein
HQ395_06435	COG0668	transmembrane transport
HQ395_06445	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HQ395_06485	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
HQ395_06495	COG0488	(ABC) transporter
HQ395_06500	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
HQ395_06500	COG0517	IMP dehydrogenase activity
HQ395_06505	COG1585	Membrane protein implicated in regulation of membrane protease activity
HQ395_06510	COG0330	HflC and HflK could
HQ395_06520	COG0175	sulfate reduction
HQ395_06525	COG2895	sulfate adenylyltransferase (ATP) activity
HQ395_06530	COG3273	potassium ion transport
HQ395_06530	COG0471	metal ion transport
HQ395_06535	COG0529	Catalyzes the synthesis of activated sulfate
HQ395_06550	COG5433	transposase activity
HQ395_06575	COG0840	transmembrane signaling receptor activity
HQ395_06595	COG1136	(ABC) transporter
HQ395_06610	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
HQ395_06625	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
HQ395_06630	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
HQ395_06635	COG0163	prenyltransferase activity
HQ395_06650	COG1131	(ABC) transporter
HQ395_06655	COG0842	Transport permease protein
HQ395_06660	COG1775	2-hydroxyglutaryl-CoA dehydratase, D-component
HQ395_06665	COG1924	4 iron, 4 sulfur cluster binding
HQ395_06685	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
HQ395_06690	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
HQ395_06705	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
HQ395_06710	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
HQ395_06715	COG1489	DNA binding
HQ395_06725	COG1643	Atp-dependent helicase
HQ395_06730	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
HQ395_06735	COG0346	lactoylglutathione lyase activity
HQ395_06745	COG2076	Multidrug Resistance protein
HQ395_06755	COG0784	Response regulator, receiver
HQ395_06755	COG3437	response regulator, receiver
HQ395_06765	COG0671	phosphoesterase, PA-phosphatase related
HQ395_06780	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
HQ395_06785	COG0038	chloride channel
HQ395_06795	COG0316	Belongs to the HesB IscA family
HQ395_06820	COG1280	lysine exporter protein (LysE YggA)
HQ395_06850	COG0789	Transcriptional regulator
HQ395_06860	COG2916	Histone family protein nucleoid-structuring protein H-NS
HQ395_06870	COG3311	Transcriptional regulator
HQ395_06920	COG2003	Belongs to the UPF0758 family
HQ395_06925	COG4584	PFAM Integrase catalytic
HQ395_06930	COG1484	DNA-dependent DNA replication
HQ395_06975	COG1196	nuclear chromosome segregation
HQ395_06990	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
HQ395_06995	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
HQ395_07010	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HQ395_07040	COG0745	RESPONSE REGULATOR receiver
HQ395_07045	COG3104	oligopeptide transport
HQ395_07050	COG1210	Utp--glucose-1-phosphate uridylyltransferase
HQ395_07055	COG1555	photosystem II stabilization
HQ395_07065	COG2350	Protein conserved in bacteria
HQ395_07070	COG2917	probably involved in intracellular septation
HQ395_07075	COG0076	glutamate decarboxylase activity
HQ395_07080	COG1272	protein, Hemolysin III
HQ395_07085	COG2985	domain, Protein
HQ395_07085	COG0569	domain protein
HQ395_07095	COG0784	Response regulator, receiver
HQ395_07095	COG0835	chemotaxis
HQ395_07100	COG2755	lipolytic protein G-D-S-L family
HQ395_07105	COG4181	ATPase activity
HQ395_07110	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
HQ395_07115	COG1090	epimerase
HQ395_07120	COG2200	EAL domain
HQ395_07125	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HQ395_07130	COG2234	aminopeptidase activity
HQ395_07130	COG4935	Belongs to the peptidase S8 family
HQ395_07135	COG0220	tRNA (guanine-N7-)-methyltransferase activity
HQ395_07140	COG3171	Protein conserved in bacteria
HQ395_07145	COG2066	Belongs to the glutaminase family
HQ395_07150	COG2897	thiosulfate sulfurtransferase activity
HQ395_07165	COG1132	(ABC) transporter
HQ395_07185	COG0582	viral genome integration into host DNA
HQ395_07195	COG5433	transposase activity
HQ395_07215	COG3447	MASE1 domain protein
HQ395_07215	COG5002	protein histidine kinase activity
HQ395_07215	COG5001	Diguanylate cyclase
HQ395_07220	COG4974	Belongs to the 'phage' integrase family
HQ395_07255	COG3039	Transposase
HQ395_07270	COG3076	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome
HQ395_07275	COG3300	MHYT domain
HQ395_07275	COG5001	Diguanylate cyclase
HQ395_07285	COG2207	Transcriptional regulator
HQ395_07290	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
HQ395_07295	COG3059	membrane
HQ395_07310	COG4628	conserved protein (DUF2132)
HQ395_07315	COG0688	phosphatidylethanolamine metabolic process
HQ395_07320	COG1162	GTPase activity
HQ395_07325	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
HQ395_07365	COG1278	Cold shock
HQ395_07375	COG0840	transmembrane signaling receptor activity
HQ395_07380	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
HQ395_07430	COG0848	biopolymer transport protein
HQ395_07435	COG0811	peptide transport
HQ395_07440	COG0811	peptide transport
HQ395_07455	COG4174	ABC transporter (Permease)
HQ395_07460	COG4239	(ABC) transporter, permease
HQ395_07470	COG0444	Belongs to the ABC transporter superfamily
HQ395_07475	COG4608	Belongs to the ABC transporter superfamily
HQ395_07480	COG2195	Cleaves the N-terminal amino acid of tripeptides
HQ395_07485	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
HQ395_07490	COG1073	alpha beta
HQ395_07505	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
HQ395_07540	COG1522	sequence-specific DNA binding
HQ395_07540	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HQ395_07545	COG2313	pseudouridylate synthase activity
HQ395_07555	COG1858	cytochrome C peroxidase
HQ395_07590	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
HQ395_07595	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
HQ395_07645	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
HQ395_07655	COG1028	Short-chain dehydrogenase reductase Sdr
HQ395_07670	COG0521	Mo-molybdopterin cofactor biosynthetic process
HQ395_07680	COG2966	Psort location CytoplasmicMembrane, score
HQ395_07685	COG3610	response to peptide
HQ395_07695	COG4175	Glycine betaine
HQ395_07700	COG4176	ABC-type proline glycine betaine transport system permease component
HQ395_07705	COG2113	Glycine betaine
HQ395_07710	COG0175	sulfate reduction
HQ395_07715	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
HQ395_07720	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
HQ395_07725	COG0384	phenazine biosynthesis protein PhzF
HQ395_07730	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
HQ395_07745	COG0786	glutamate:sodium symporter activity
HQ395_07750	COG0252	asparaginase activity
HQ395_07755	COG3139	Protein of unknown function (DUF1315)
HQ395_07775	COG0616	signal peptide processing
HQ395_07780	COG0446	pyridine nucleotide-disulphide oxidoreductase
HQ395_07780	COG1902	pentaerythritol trinitrate reductase activity
HQ395_07785	COG0778	Nitroreductase
HQ395_07800	COG2264	protein methyltransferase activity
HQ395_07805	COG0604	alcohol dehydrogenase
HQ395_07810	COG0583	DNA-binding transcription factor activity
HQ395_07815	COG1263	PTS System
HQ395_07815	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HQ395_07815	COG2190	(PTS) system
HQ395_07820	COG4145	pantothenate transmembrane transporter activity
HQ395_07830	COG0439	Biotin carboxylase
HQ395_07835	COG0511	ligase activity, forming carbon-carbon bonds
HQ395_07840	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
HQ395_07845	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
HQ395_07855	COG3300	MHYT domain
HQ395_07855	COG5001	Diguanylate cyclase
HQ395_07875	COG3381	protein complex oligomerization
HQ395_07890	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
HQ395_07905	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
HQ395_07910	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
HQ395_07910	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
HQ395_07930	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
HQ395_07935	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
HQ395_07940	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
HQ395_07945	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
HQ395_07950	COG4172	Belongs to the ABC transporter superfamily
HQ395_07960	COG0601	transmembrane transport
HQ395_07970	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
HQ395_07975	COG0142	geranyltranstransferase activity
HQ395_07980	COG1722	exodeoxyribonuclease VII activity
HQ395_07985	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
HQ395_07990	COG1360	Flagellar Motor Protein
HQ395_08005	COG1534	Rna-binding protein
HQ395_08010	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
HQ395_08020	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
HQ395_08025	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
HQ395_08030	COG0149	triose-phosphate isomerase activity
HQ395_08035	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
HQ395_08050	COG0779	Required for maturation of 30S ribosomal subunits
HQ395_08055	COG0195	Participates in both transcription termination and antitermination
HQ395_08060	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
HQ395_08065	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
HQ395_08070	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
HQ395_08075	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
HQ395_08080	COG1185	polyribonucleotide nucleotidyltransferase activity
HQ395_08085	COG2211	Major facilitator Superfamily
HQ395_08095	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
HQ395_08105	COG0114	fumarate hydratase activity
HQ395_08115	COG1966	Carbon starvation protein
HQ395_08120	COG3279	Response regulator of the LytR AlgR family
HQ395_08125	COG3275	phosphorelay sensor kinase activity
HQ395_08190	COG0312	modulator of DNA gyrase
HQ395_08205	COG4974	Belongs to the 'phage' integrase family
HQ395_08210	COG1970	mechanosensitive ion channel activity
HQ395_08215	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
HQ395_08230	COG0789	Transcriptional regulator
HQ395_08245	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
HQ395_08250	COG3545	Serine hydrolase
HQ395_08260	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
HQ395_08265	COG0321	lipoyl(octanoyl) transferase activity
HQ395_08270	COG2921	Belongs to the UPF0250 family
HQ395_08275	COG1686	Belongs to the peptidase S11 family
HQ395_08280	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
HQ395_08285	COG2951	lytic endotransglycosylase activity
HQ395_08290	COG0772	Belongs to the SEDS family
HQ395_08295	COG0768	penicillin binding
HQ395_08300	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
HQ395_08305	COG0799	negative regulation of ribosome biogenesis
HQ395_08310	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
HQ395_08325	COG0495	leucyl-tRNA aminoacylation
HQ395_08330	COG2888	peptidyl-tyrosine sulfation
HQ395_08335	COG0815	Transfers the fatty acyl group on membrane lipoproteins
HQ395_08340	COG4535	Mg2 and Co2 transporter CorC
HQ395_08345	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
HQ395_08350	COG1702	phosphate starvation-inducible protein PhoH
HQ395_08360	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
HQ395_08365	COG1335	isochorismatase
HQ395_08375	COG3706	GGDEF domain
HQ395_08390	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
HQ395_08410	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HQ395_08420	COG3647	Membrane
HQ395_08425	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
HQ395_08435	COG0516	GMP reductase activity
HQ395_08455	COG0642	Histidine kinase
HQ395_08490	COG4106	trans-aconitate 2-methyltransferase activity
HQ395_08495	COG3214	Protein conserved in bacteria
HQ395_08520	COG3029	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
HQ395_08525	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
HQ395_08530	COG1053	succinate dehydrogenase
HQ395_08540	COG0584	glycerophosphoryl diester phosphodiesterase
HQ395_08545	COG1511	domain protein
HQ395_08545	COG3264	Mechanosensitive ion channel
HQ395_08555	COG0739	heme binding
HQ395_08570	COG0583	DNA-binding transcription factor activity
HQ395_08590	COG0583	DNA-binding transcription factor activity
HQ395_08595	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
HQ395_08625	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
HQ395_08630	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
HQ395_08640	COG0338	D12 class N6 adenine-specific DNA methyltransferase
HQ395_08645	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
HQ395_08655	COG0180	Tryptophanyl-tRNA synthetase
HQ395_08670	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
HQ395_08680	COG1012	belongs to the aldehyde dehydrogenase family
HQ395_08705	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
HQ395_08715	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
HQ395_08715	COG1013	pyruvate-flavodoxin oxidoreductase activity
HQ395_08715	COG0674	pyruvate-flavodoxin oxidoreductase activity
HQ395_08715	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
HQ395_08725	COG0366	Alpha amylase catalytic
HQ395_08755	COG0471	metal ion transport
HQ395_08755	COG0490	domain, Protein
HQ395_08825	COG3177	Filamentation induced by cAMP protein fic
HQ395_08830	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HQ395_08855	COG5433	transposase activity
HQ395_08875	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
HQ395_08900	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
HQ395_08905	COG2003	Belongs to the UPF0758 family
HQ395_08950	COG5377	YqaJ viral recombinase family
HQ395_08960	COG0012	GTP binding
HQ395_08965	COG0193	aminoacyl-tRNA hydrolase activity
HQ395_08970	COG0737	Belongs to the 5'-nucleotidase family
HQ395_08975	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HQ395_08985	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
HQ395_08990	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
HQ395_08995	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
HQ395_09000	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
HQ395_09005	COG2890	protein-(glutamine-N5) methyltransferase activity
HQ395_09015	COG2912	Transglutaminase-like superfamily
HQ395_09020	COG2877	3-deoxy-8-phosphooctulonate synthase activity
HQ395_09025	COG1301	dicarboxylic acid transport
HQ395_09035	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
HQ395_09050	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
HQ395_09055	COG1115	amino acid carrier protein
HQ395_09070	COG0714	Associated with various cellular activities
HQ395_09080	COG3104	oligopeptide transport
HQ395_09085	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
HQ395_09090	COG1678	Uncharacterized ACR, COG1678
HQ395_09100	COG0189	ligase activity
HQ395_09105	COG1385	rRNA (uridine-N3-)-methyltransferase activity
HQ395_09115	COG3091	SprT-like family
HQ395_09240	COG0640	Transcriptional regulator
HQ395_09250	COG4373	Mu-like prophage FluMu protein gp28
HQ395_09255	COG4383	Mu-like prophage protein gp29
HQ395_09275	COG4388	Caudovirus prohead serine protease
HQ395_09280	COG4397	Mu-like prophage major head subunit gpT
HQ395_09355	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
HQ395_09380	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
HQ395_09385	COG0739	heme binding
HQ395_09390	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
HQ395_09395	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
HQ395_09395	COG3408	Glycogen debranching enzyme
HQ395_09405	COG1881	PFAM PEBP family protein
HQ395_09410	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
HQ395_09415	COG0583	DNA-binding transcription factor activity
HQ395_09425	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
HQ395_09435	COG0583	DNA-binding transcription factor activity
HQ395_09440	COG1028	Short-chain dehydrogenase reductase Sdr
HQ395_09445	COG0616	signal peptide processing
HQ395_09450	COG3724	N-succinylarginine dihydrolase activity
HQ395_09470	COG0840	transmembrane signaling receptor activity
HQ395_09480	COG2971	BadF BadG BcrA BcrD
HQ395_09490	COG4608	Belongs to the ABC transporter superfamily
HQ395_09495	COG0444	Belongs to the ABC transporter superfamily
HQ395_09500	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
HQ395_09505	COG0601	transmembrane transport
HQ395_09510	COG4166	transmembrane transport
HQ395_09515	COG0784	Response regulator, receiver
HQ395_09515	COG2205	protein histidine kinase activity
HQ395_09545	COG3220	belongs to the UPF0276 family
HQ395_09575	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
HQ395_09580	COG1289	transmembrane transporter activity
HQ395_09585	COG0303	'Molybdopterin
HQ395_09590	COG0746	molybdenum cofactor guanylyltransferase activity
HQ395_09600	COG4662	Binding-protein-dependent transport system inner membrane component
HQ395_09610	COG2204	response regulator
HQ395_09615	COG3852	Histidine kinase
HQ395_09620	COG1910	domain protein
HQ395_09625	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
HQ395_09660	COG3383	formate dehydrogenase (NAD+) activity
HQ395_09660	COG3383	formate dehydrogenase (NAD+) activity
HQ395_09665	COG0437	4 iron, 4 sulfur cluster binding
HQ395_09680	COG0281	malic enzyme
HQ395_09690	COG2706	6-phosphogluconolactonase activity
HQ395_09700	COG1196	nuclear chromosome segregation
HQ395_09700	COG3264	Mechanosensitive ion channel
HQ395_09705	COG0469	pyruvate kinase activity
HQ395_09720	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
HQ395_09720	COG4651	solute:proton antiporter activity
HQ395_09725	COG0405	Gamma-glutamyltransferase
HQ395_09730	COG2974	May be involved in recombination
HQ395_09740	COG0420	3'-5' exonuclease activity
HQ395_09745	COG0419	ATPase involved in DNA repair
HQ395_09760	COG3038	cytochrome b561
HQ395_09775	COG2190	(PTS) system
HQ395_09785	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
HQ395_09790	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
HQ395_09795	COG0542	response to heat
HQ395_09810	COG1720	tRNA m6t6A37 methyltransferase activity
HQ395_09830	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
HQ395_09835	COG4988	ABC transporter
HQ395_09850	COG0745	RESPONSE REGULATOR receiver
HQ395_09860	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
HQ395_09875	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
HQ395_09880	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
HQ395_09890	COG0083	homoserine kinase activity
HQ395_09895	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
HQ395_09905	COG0488	(ABC) transporter
HQ395_09920	COG0813	purine-nucleoside phosphorylase activity
HQ395_09935	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HQ395_09935	COG2205	protein histidine kinase activity
HQ395_09940	COG3384	dioxygenase
HQ395_09960	COG0531	amino acid
HQ395_09970	COG0531	amino acid
HQ395_09985	COG1917	Cupin 2, conserved barrel domain protein
HQ395_09985	COG1396	sequence-specific DNA binding
HQ395_09990	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
HQ395_10010	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
HQ395_10015	COG2375	cellular response to nickel ion
HQ395_10025	COG0577	efflux transmembrane transporter activity
HQ395_10025	COG1136	(ABC) transporter
HQ395_10030	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HQ395_10040	COG1227	inorganic diphosphatase activity
HQ395_10050	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
HQ395_10055	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
HQ395_10060	COG0443	Heat shock 70 kDa protein
HQ395_10065	COG0484	heat shock protein binding
HQ395_10095	COG1285	pathogenesis
HQ395_10110	COG0640	Transcriptional regulator
HQ395_10140	COG0095	Lipoate-protein ligase
HQ395_10160	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HQ395_10165	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HQ395_10185	COG0708	Exodeoxyribonuclease III
HQ395_10245	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
HQ395_10250	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
HQ395_10255	COG1845	cytochrome c oxidase, subunit III
HQ395_10260	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
HQ395_10265	COG0109	protoheme IX farnesyltransferase activity
HQ395_10270	COG2814	Major facilitator Superfamily
HQ395_10280	COG2175	clavaminate synthase activity
HQ395_10285	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
HQ395_10290	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
HQ395_10295	COG4521	taurine ABC transporter
HQ395_10325	COG1988	membrane-bound metal-dependent
HQ395_10350	COG0159	tryptophan synthase activity
HQ395_10355	COG0133	tryptophan synthase activity
HQ395_10360	COG0134	indole-3-glycerol-phosphate synthase activity
HQ395_10360	COG0135	phosphoribosylanthranilate isomerase activity
HQ395_10365	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
HQ395_10370	COG0512	Glutamine amidotransferase of anthranilate synthase
HQ395_10370	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
HQ395_10375	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
HQ395_10385	COG0009	L-threonylcarbamoyladenylate synthase
HQ395_10395	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
HQ395_10405	COG1946	Acyl-CoA thioesterase
HQ395_10420	COG1309	transcriptional regulator
HQ395_10425	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HQ395_10430	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HQ395_10445	COG1091	dTDP-4-dehydrorhamnose reductase activity
HQ395_10465	COG1459	type II secretion system
HQ395_10475	COG2165	general secretion pathway protein
HQ395_10510	COG1450	Type ii and iii secretion system protein
HQ395_10535	COG3562	capsule polysaccharide
HQ395_10540	COG2755	lipolytic protein G-D-S-L family
HQ395_10540	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
HQ395_10555	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
HQ395_10570	COG0463	Glycosyl transferase, family 2
HQ395_10575	COG0438	transferase activity, transferring glycosyl groups
HQ395_10585	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
HQ395_10595	COG3132	Protein of unknown function, DUF480
HQ395_10635	COG1278	Cold shock
HQ395_10665	COG0697	spore germination
HQ395_10670	COG1349	DNA-binding transcription factor activity
HQ395_10675	COG1882	Formate acetyltransferase
HQ395_10680	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HQ395_10685	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
HQ395_10715	COG0622	Phosphoesterase
HQ395_10730	COG1261	Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly
HQ395_10735	COG0835	chemotaxis
HQ395_10735	COG0784	Response regulator, receiver
HQ395_10740	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
HQ395_10745	COG1815	bacterial-type flagellum-dependent cell motility
HQ395_10760	COG1749	Flagellar hook protein flgE
HQ395_10770	COG4787	bacterial-type flagellum-dependent cell motility
HQ395_10780	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
HQ395_10785	COG1706	bacterial-type flagellum-dependent cell motility
HQ395_10790	COG3951	Flagellar rod assembly protein muramidase FlgJ
HQ395_10790	COG1705	Flagellar rod assembly protein muramidase FlgJ
HQ395_10805	COG2239	Acts as a magnesium transporter
HQ395_10815	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
HQ395_10820	COG2716	regulation of RNA biosynthetic process
HQ395_10845	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
HQ395_10850	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
HQ395_10855	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
HQ395_10860	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
HQ395_10880	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
HQ395_10895	COG0590	tRNA wobble adenosine to inosine editing
HQ395_10900	COG0573	inorganic phosphate transmembrane transporter activity
HQ395_10905	COG0581	inorganic phosphate transmembrane transporter activity
HQ395_10910	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
HQ395_10915	COG0704	Plays a role in the regulation of phosphate uptake
HQ395_10920	COG1253	flavin adenine dinucleotide binding
HQ395_10935	COG0531	amino acid
HQ395_10955	COG1126	abc transporter atp-binding protein
HQ395_10960	COG0765	amino acid transport
HQ395_10965	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HQ395_10975	COG2271	Major facilitator Superfamily
HQ395_10990	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
HQ395_11015	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
HQ395_11020	COG0477	Major facilitator Superfamily
HQ395_11025	COG0123	including yeast histone deacetylase and acetoin utilization protein
HQ395_11035	COG1199	ATP-dependent helicase activity
HQ395_11050	COG1448	Aminotransferase
HQ395_11055	COG0433	COG0433 Predicted ATPase
HQ395_11070	COG0658	competence protein
HQ395_11070	COG2333	competence protein COMEC
HQ395_11080	COG1663	tetraacyldisaccharide 4'-kinase activity
HQ395_11085	COG2835	tetraacyldisaccharide 4'-kinase activity
HQ395_11090	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
HQ395_11095	COG2197	response regulator
HQ395_11100	COG0322	excinuclease ABC activity
HQ395_11370	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
HQ395_11385	COG4974	Belongs to the 'phage' integrase family
HQ395_11435	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
HQ395_11440	COG0437	4 iron, 4 sulfur cluster binding
HQ395_11445	COG3301	Polysulphide reductase, NrfD
HQ395_11450	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
HQ395_11460	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
HQ395_11485	COG2203	Gaf domain
HQ395_11485	COG2199	diguanylate cyclase activity
HQ395_11515	COG2119	membrane
HQ395_11520	COG0023	Translation Initiation Factor
HQ395_11545	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
HQ395_11560	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HQ395_11560	COG2205	protein histidine kinase activity
HQ395_11570	COG4138	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system
HQ395_11580	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
HQ395_11585	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
HQ395_11590	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
HQ395_11595	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
HQ395_11600	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
HQ395_11610	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
HQ395_11615	COG0505	Belongs to the CarA family
HQ395_11620	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
HQ395_11625	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
HQ395_11655	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HQ395_11660	COG0513	Belongs to the DEAD box helicase family
HQ395_11670	COG4104	PAAR repeat-containing protein
HQ395_11685	COG0789	Transcriptional regulator
HQ395_11700	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HQ395_11705	COG0765	amino acid transport
HQ395_11710	COG1126	abc transporter atp-binding protein
HQ395_11715	COG0493	'glutamate synthase
HQ395_11720	COG0067	glutamate synthase
HQ395_11720	COG0069	glutamate synthase activity
HQ395_11720	COG0070	glutamate synthase
HQ395_11725	COG1242	4 iron, 4 sulfur cluster binding
HQ395_11765	COG2304	oxidoreductase activity
HQ395_11790	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
HQ395_11795	COG0574	Belongs to the PEP-utilizing enzyme family
HQ395_11795	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HQ395_11835	COG1464	Belongs to the NlpA lipoprotein family
HQ395_11840	COG0671	phosphoesterase, PA-phosphatase related
HQ395_11845	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
HQ395_11850	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
HQ395_11860	COG0101	tRNA pseudouridine synthase activity
HQ395_11865	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
HQ395_11870	COG0285	dihydrofolate synthase activity
HQ395_11875	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
HQ395_11880	COG2920	part of a sulfur-relay system
HQ395_11885	COG1289	transmembrane transporter activity
HQ395_11890	COG0670	Belongs to the BI1 family
HQ395_11905	COG4792	protein secretion
HQ395_11910	COG4791	protein targeting
HQ395_11915	COG4794	Type iii secretion
HQ395_12080	COG1317	bacterial-type flagellum organization
HQ395_12095	COG2194	sulfuric ester hydrolase activity
HQ395_12100	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
HQ395_12100	COG0392	lysyltransferase activity
HQ395_12110	COG0840	transmembrane signaling receptor activity
HQ395_12115	COG5001	Diguanylate cyclase
HQ395_12120	COG0564	pseudouridine synthase activity
HQ395_12135	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
HQ395_12145	COG0625	glutathione transferase activity
HQ395_12150	COG0625	glutathione transferase activity
HQ395_12160	COG0367	asparagine synthase
HQ395_12170	COG4651	solute:proton antiporter activity
HQ395_12170	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
HQ395_12175	COG0647	UMP catabolic process
HQ395_12185	COG1902	pentaerythritol trinitrate reductase activity
HQ395_12190	COG1253	flavin adenine dinucleotide binding
HQ395_12200	COG0277	FAD linked oxidase domain protein
HQ395_12200	COG0247	lactate metabolic process
HQ395_12210	COG2050	protein possibly involved in aromatic compounds catabolism
HQ395_12220	COG2056	Na+-H+ antiporter family
HQ395_12225	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
HQ395_12240	COG0346	lactoylglutathione lyase activity
HQ395_12245	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
HQ395_12250	COG4660	Part of a membrane complex involved in electron transport
HQ395_12255	COG4659	FMN binding
HQ395_12260	COG4658	electron transport chain
HQ395_12270	COG2878	Part of a membrane complex involved in electron transport
HQ395_12275	COG4657	Part of a membrane complex involved in electron transport
HQ395_12280	COG0697	spore germination
HQ395_12295	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
HQ395_12300	COG1288	antiporter activity
HQ395_12305	COG0436	Aminotransferase
HQ395_12315	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
HQ395_12320	COG2027	D-alanyl-D-alanine carboxypeptidase
HQ395_12325	COG1061	Type III restriction enzyme res subunit
HQ395_12330	COG1566	PFAM secretion protein HlyD family protein
HQ395_12340	COG1966	Carbon starvation protein
HQ395_12345	COG3279	Response regulator of the LytR AlgR family
HQ395_12350	COG3275	phosphorelay sensor kinase activity
HQ395_12355	COG2199	diguanylate cyclase activity
HQ395_12355	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
HQ395_12360	COG1454	alcohol dehydrogenase
HQ395_12360	COG1012	belongs to the aldehyde dehydrogenase family
HQ395_12370	COG2095	MarC family integral membrane protein
HQ395_12380	COG0601	transmembrane transport
HQ395_12385	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
HQ395_12400	COG0861	Integral membrane protein TerC family
HQ395_12405	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HQ395_12415	COG1301	dicarboxylic acid transport
HQ395_12430	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
HQ395_12445	COG0537	adenosine 5'-monophosphoramidase activity
HQ395_12480	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
HQ395_12485	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
HQ395_12500	COG2354	Protein conserved in bacteria
HQ395_12515	COG2233	PERMEase
HQ395_12520	COG3150	esterase
HQ395_12525	COG1252	NADH dehydrogenase
HQ395_12545	COG0393	Putative heavy-metal-binding
HQ395_12575	COG4667	esterase of the alpha-beta hydrolase superfamily
HQ395_12580	COG1619	proteins homologs of microcin C7 resistance protein MccF
HQ395_12585	COG1368	sulfuric ester hydrolase activity
HQ395_12595	COG0527	aspartate kinase activity
HQ395_12605	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HQ395_12625	COG0596	Alpha beta hydrolase
HQ395_12630	COG0346	lactoylglutathione lyase activity
HQ395_12640	COG0583	DNA-binding transcription factor activity
HQ395_12645	COG1620	l-lactate permease
HQ395_12700	COG2814	Major facilitator Superfamily
HQ395_12720	COG0672	)-iron permease
HQ395_12750	COG0659	secondary active sulfate transmembrane transporter activity
HQ395_12775	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
HQ395_12795	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HQ395_12800	COG0840	transmembrane signaling receptor activity
HQ395_12810	COG2201	protein-glutamate methylesterase activity
HQ395_12820	COG0835	chemotaxis
HQ395_12825	COG0840	transmembrane signaling receptor activity
HQ395_12825	COG3290	protein histidine kinase activity
HQ395_12830	COG0643	Histidine kinase
HQ395_12830	COG2198	Histidine kinase
HQ395_12840	COG0745	RESPONSE REGULATOR receiver
HQ395_12845	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
HQ395_12850	COG0437	4 iron, 4 sulfur cluster binding
HQ395_12860	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
HQ395_12865	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
HQ395_12870	COG1773	rubredoxin
HQ395_12880	COG0601	transmembrane transport
HQ395_12885	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
HQ395_12890	COG0444	Belongs to the ABC transporter superfamily
HQ395_12895	COG1124	(ABC) transporter
HQ395_12900	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
HQ395_12905	COG0375	protein maturation
HQ395_12910	COG0309	Hydrogenase expression formation protein (HypE)
HQ395_12920	COG0298	carbon dioxide binding
HQ395_12925	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
HQ395_12935	COG1921	L-seryl-tRNASec selenium transferase activity
HQ395_12945	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
HQ395_12955	COG3260	NADH ubiquinone oxidoreductase 20
HQ395_12960	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
HQ395_12965	COG3261	NADH dehydrogenase
HQ395_12965	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
HQ395_12970	COG0650	Formate hydrogenlyase subunit 4
HQ395_12975	COG0651	ATP synthesis coupled electron transport
HQ395_12980	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
HQ395_12985	COG3158	transport of potassium into the cell
HQ395_13000	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
HQ395_13025	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
HQ395_13030	COG0326	Molecular chaperone. Has ATPase activity
HQ395_13035	COG0563	adenylate kinase activity
HQ395_13040	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
HQ395_13050	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HQ395_13065	COG3300	MHYT domain
HQ395_13065	COG5001	Diguanylate cyclase
HQ395_13070	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
HQ395_13090	COG1021	2,3-dihydroxybenzoate-AMP ligase
HQ395_13095	COG1535	isochorismatase
HQ395_13095	COG3433	isochorismatase activity
HQ395_13100	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HQ395_13105	COG1028	Short-chain dehydrogenase reductase Sdr
HQ395_13115	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HQ395_13120	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
HQ395_13130	COG1120	ATPase activity
HQ395_13135	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HQ395_13140	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HQ395_13145	COG4771	TonB-dependent receptor
HQ395_13185	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
HQ395_13190	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
HQ395_13195	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
HQ395_13210	COG1570	exodeoxyribonuclease VII activity
HQ395_13235	COG3158	transport of potassium into the cell
HQ395_13240	COG0516	GMP reductase activity
HQ395_13240	COG0517	IMP dehydrogenase activity
HQ395_13245	COG0518	GMP synthase (glutamine-hydrolyzing) activity
HQ395_13245	COG0519	Catalyzes the synthesis of GMP from XMP
HQ395_13295	COG2062	phosphohistidine phosphatase, SixA
HQ395_13305	COG0697	spore germination
HQ395_13310	COG4166	transmembrane transport
HQ395_13315	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
HQ395_13320	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
HQ395_13330	COG4591	ABC-type transport system involved in lipoprotein release permease component
HQ395_13335	COG1136	(ABC) transporter
HQ395_13340	COG4591	ABC-type transport system involved in lipoprotein release permease component
HQ395_13345	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
HQ395_13355	COG0544	peptidyl-prolyl cis-trans isomerase activity
HQ395_13360	COG0740	serine-type endopeptidase activity
HQ395_13365	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
HQ395_13370	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
HQ395_13375	COG0776	regulation of translation
HQ395_13380	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
HQ395_13385	COG0488	(ABC) transporter
HQ395_13390	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HQ395_13395	COG3162	membrane
HQ395_13410	COG1024	Enoyl-CoA hydratase
HQ395_13540	COG4695	Portal protein
HQ395_13665	COG4974	Belongs to the 'phage' integrase family
HQ395_13670	COG1115	amino acid carrier protein
HQ395_13685	COG1584	GPR1 FUN34 yaaH family protein
HQ395_13720	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
HQ395_13725	COG1960	acyl-CoA dehydrogenase activity
HQ395_13735	COG1960	acyl-CoA dehydrogenase activity
HQ395_13740	COG1024	Enoyl-CoA hydratase
HQ395_13745	COG1024	Enoyl-CoA hydratase
HQ395_13755	COG1028	Short-chain dehydrogenase reductase Sdr
HQ395_13765	COG0730	response to heat
HQ395_13775	COG0583	DNA-binding transcription factor activity
HQ395_13780	COG0667	Aldo Keto reductase
HQ395_13790	COG3706	GGDEF domain
HQ395_13795	COG0583	DNA-binding transcription factor activity
HQ395_13800	COG2723	6-phospho-beta-galactosidase activity
HQ395_13805	COG3300	MHYT domain
HQ395_13805	COG5001	Diguanylate cyclase
HQ395_13815	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
HQ395_13820	COG1028	Short-chain dehydrogenase reductase Sdr
HQ395_13825	COG0583	DNA-binding transcription factor activity
HQ395_13830	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
HQ395_13835	COG0673	inositol 2-dehydrogenase activity
HQ395_13840	COG0583	DNA-binding transcription factor activity
HQ395_13850	COG1560	Kdo2-lipid A biosynthetic process
HQ395_13855	COG1560	Kdo2-lipid A biosynthetic process
HQ395_13870	COG2199	diguanylate cyclase activity
HQ395_13870	COG2203	Gaf domain
HQ395_13880	COG0417	DNA replication proofreading
HQ395_13910	COG0534	Mate efflux family protein
HQ395_13920	COG0307	riboflavin synthase, alpha
HQ395_13930	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
HQ395_13935	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
HQ395_13945	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
HQ395_13985	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
HQ395_13990	COG3099	Belongs to the UPF0263 family
HQ395_13995	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
HQ395_14000	COG2894	cell division
HQ395_14005	COG0850	regulation of cytokinetic process
HQ395_14010	COG3100	YcgL domain-containing protein
HQ395_14015	COG2951	lytic endotransglycosylase activity
HQ395_14020	COG1760	l-serine dehydratase
HQ395_14025	COG1760	l-serine dehydratase
HQ395_14050	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
HQ395_14055	COG2067	long-chain fatty acid transport protein
HQ395_14075	COG1595	DNA-templated transcription, initiation
HQ395_14105	COG0714	Associated with various cellular activities
HQ395_14110	COG0183	Belongs to the thiolase family
HQ395_14115	COG1250	3-hydroxyacyl-CoA dehydrogenase
HQ395_14115	COG1024	Enoyl-CoA hydratase
HQ395_14135	COG2932	Transcriptional regulator
HQ395_14240	COG0640	Transcriptional regulator
HQ395_14250	COG4373	Mu-like prophage FluMu protein gp28
HQ395_14255	COG4383	Mu-like prophage protein gp29
HQ395_14290	COG4388	Caudovirus prohead serine protease
HQ395_14295	COG4397	Mu-like prophage major head subunit gpT
HQ395_14405	COG3829	transcription factor binding
HQ395_14410	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
HQ395_14415	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
HQ395_14420	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
HQ395_14430	COG0549	Belongs to the carbamate kinase family
HQ395_14435	COG0697	spore germination
HQ395_14440	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
HQ395_14440	COG3608	succinylglutamate desuccinylase aspartoacylase
HQ395_14445	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
HQ395_14455	COG0493	'glutamate synthase
HQ395_14455	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
HQ395_14460	COG0402	S-adenosylhomocysteine deaminase activity
HQ395_14465	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
HQ395_14475	COG2233	PERMEase
HQ395_14480	COG0402	S-adenosylhomocysteine deaminase activity
HQ395_14485	COG2252	PERMEase
HQ395_14490	COG1529	Aldehyde oxidase and xanthine dehydrogenase
HQ395_14495	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
HQ395_14500	COG2080	2 iron, 2 sulfur cluster binding
HQ395_14510	COG3134	Outer membrane lipoprotein
HQ395_14520	COG1288	antiporter activity
HQ395_14525	COG0318	PFAM AMP-dependent synthetase and ligase
HQ395_14535	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
HQ395_14535	COG0140	phosphoribosyl-ATP diphosphatase activity
HQ395_14540	COG0107	imidazoleglycerol-phosphate synthase activity
HQ395_14545	COG2205	protein histidine kinase activity
HQ395_14545	COG0784	Response regulator, receiver
HQ395_14545	COG2198	Histidine kinase
HQ395_14550	COG2199	diguanylate cyclase activity
HQ395_14555	COG3437	response regulator, receiver
HQ395_14560	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
HQ395_14565	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
HQ395_14570	COG0131	Imidazoleglycerol-phosphate dehydratase
HQ395_14570	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
HQ395_14575	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
HQ395_14580	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
HQ395_14585	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
HQ395_14595	COG1199	ATP-dependent helicase activity
HQ395_14600	COG1214	PFAM Peptidase M22, glycoprotease
HQ395_14610	COG0596	Alpha beta hydrolase
HQ395_14610	COG2226	methyltransferase
HQ395_14610	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
HQ395_14615	COG0318	PFAM AMP-dependent synthetase and ligase
HQ395_14635	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HQ395_14640	COG2832	Protein of unknown function (DUF454)
HQ395_14645	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
HQ395_14655	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
HQ395_14675	COG0517	IMP dehydrogenase activity
HQ395_14675	COG0617	tRNA 3'-terminal CCA addition
HQ395_14675	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
HQ395_14680	COG1643	Atp-dependent helicase
HQ395_14690	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
HQ395_14700	COG3437	response regulator, receiver
HQ395_14705	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
HQ395_14710	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
HQ395_14715	COG0709	Synthesizes selenophosphate from selenide and ATP
HQ395_14730	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
HQ395_14740	COG1254	Belongs to the acylphosphatase family
HQ395_14745	COG0625	glutathione transferase activity
HQ395_14755	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HQ395_14755	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HQ395_14760	COG0489	protein tyrosine kinase activity
HQ395_14765	COG0572	uridine kinase
HQ395_14770	COG0717	Belongs to the dCTP deaminase family
HQ395_14775	COG0306	phosphate transporter
HQ395_14780	COG1530	ribonuclease E activity
HQ395_14785	COG0564	pseudouridine synthase activity
HQ395_14790	COG0546	phosphoglycolate phosphatase activity
HQ395_14795	COG0424	maF-like protein
HQ395_14800	COG2814	Major facilitator Superfamily
HQ395_14815	COG1399	metal-binding, possibly nucleic acid-binding protein
HQ395_14820	COG0333	Belongs to the bacterial ribosomal protein bL32 family
HQ395_14825	COG0416	fatty acid biosynthetic process
HQ395_14830	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HQ395_14840	COG1028	Short-chain dehydrogenase reductase Sdr
HQ395_14845	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
HQ395_14855	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
HQ395_14860	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
HQ395_14865	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
HQ395_14870	COG0470	DNA polymerase III
HQ395_14875	COG0084	hydrolase, TatD family'
HQ395_14890	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
HQ395_14890	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
HQ395_14895	COG3008	intermembrane lipid transfer
HQ395_14900	COG2995	paraquat-inducible protein a
HQ395_14910	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
HQ395_14915	COG0372	Belongs to the citrate synthase family
HQ395_14960	COG4221	oxidoreductase activity
HQ395_14970	COG3141	response to X-ray
HQ395_14980	COG1067	ATP-dependent peptidase activity
HQ395_14985	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
HQ395_15000	COG0488	(ABC) transporter
HQ395_15010	COG0116	Belongs to the methyltransferase superfamily
HQ395_15010	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
HQ395_15020	COG0167	dihydroorotate dehydrogenase activity
HQ395_15025	COG2902	Dehydrogenase
HQ395_15035	COG0308	aminopeptidase N
HQ395_15045	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
HQ395_15050	COG1956	GAF domain-containing protein
HQ395_15060	COG3278	Belongs to the heme-copper respiratory oxidase family
HQ395_15075	COG2010	Cytochrome c
HQ395_15100	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
HQ395_15105	COG0589	response to stress
HQ395_15110	COG0037	tRNA processing
HQ395_15125	COG0625	glutathione transferase activity
HQ395_15130	COG1869	D-ribose catabolic process
HQ395_15135	COG1129	ABC transporter
HQ395_15140	COG1172	Belongs to the binding-protein-dependent transport system permease family
HQ395_15145	COG1879	ABC-type sugar transport system periplasmic component
HQ395_15150	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HQ395_15155	COG1609	Transcriptional regulator
HQ395_15160	COG3300	MHYT domain
HQ395_15160	COG5001	Diguanylate cyclase
HQ395_15190	COG0776	regulation of translation
HQ395_15195	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HQ395_15195	COG0072	phenylalanine-tRNA ligase activity
HQ395_15200	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
HQ395_15205	COG4974	Belongs to the 'phage' integrase family
HQ395_15290	COG4695	Portal protein
HQ395_15330	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
HQ395_15335	COG0291	Belongs to the bacterial ribosomal protein bL35 family
HQ395_15340	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
HQ395_15345	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
HQ395_15370	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
HQ395_15380	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HQ395_15385	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HQ395_15390	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
HQ395_15395	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
HQ395_15400	COG3313	Fe-S protein
HQ395_15410	COG3716	PTS system mannose fructose sorbose family IID component
HQ395_15415	COG3715	PTS system
HQ395_15420	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HQ395_15420	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
HQ395_15435	COG1609	Transcriptional regulator
HQ395_15440	COG2140	Oxalate decarboxylase
HQ395_15445	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HQ395_15445	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HQ395_15445	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
HQ395_15450	COG1105	Belongs to the carbohydrate kinase PfkB family
HQ395_15455	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
HQ395_15455	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
HQ395_15460	COG1609	Transcriptional regulator
HQ395_15465	COG0814	amino acid
HQ395_15475	COG0583	DNA-binding transcription factor activity
HQ395_15480	COG0513	Belongs to the DEAD box helicase family
HQ395_15490	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
HQ395_15495	COG2890	protein-(glutamine-N5) methyltransferase activity
HQ395_15500	COG2840	Smr protein MutS2
HQ395_15510	COG3706	GGDEF domain
HQ395_15515	COG0406	alpha-ribazole phosphatase activity
HQ395_15540	COG2824	Alkylphosphonate utilization operon protein PhnA
HQ395_15555	COG0384	phenazine biosynthesis protein PhzF
HQ395_15585	COG0242	peptide deformylase activity
HQ395_15595	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
HQ395_15600	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
HQ395_15605	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
HQ395_15620	COG1434	Gram-negative-bacterium-type cell wall biogenesis
HQ395_15630	COG0205	6-phosphofructokinase activity
HQ395_15635	COG1473	amidohydrolase
HQ395_15640	COG1011	Hydrolase
HQ395_15645	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
HQ395_15700	COG3593	DNA synthesis involved in DNA repair
HQ395_15715	COG0583	DNA-binding transcription factor activity
HQ395_15720	COG0730	response to heat
HQ395_15725	COG3148	PFAM DTW domain containing protein
HQ395_15735	COG1181	Belongs to the D-alanine--D-alanine ligase family
HQ395_15745	COG0386	Belongs to the glutathione peroxidase family
HQ395_15750	COG0513	Belongs to the DEAD box helicase family
HQ395_15755	COG0456	acetyltransferase
HQ395_15765	COG1742	UPF0060 membrane protein
HQ395_15795	COG2329	Antibiotic biosynthesis monooxygenase
HQ395_15800	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
HQ395_15820	COG3243	poly(R)-hydroxyalkanoic acid synthase
HQ395_15830	COG2501	S4 domain
HQ395_15840	COG1132	(ABC) transporter
HQ395_15845	COG1132	(ABC) transporter
HQ395_15855	COG3118	belongs to the thioredoxin family
HQ395_15860	COG0471	metal ion transport
HQ395_15895	COG0814	amino acid
HQ395_15900	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
HQ395_15905	COG0514	ATP-dependent DNA helicase (RecQ)
HQ395_15910	COG2766	serine protein kinase
HQ395_15920	COG2719	SpoVR family
HQ395_15925	COG2186	Transcriptional regulator
HQ395_15930	COG3067	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
HQ395_15935	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
HQ395_15940	COG0586	Pfam SNARE associated Golgi protein
HQ395_15950	COG0556	nucleotide-excision repair
HQ395_15960	COG0569	domain protein
HQ395_15960	COG2985	domain, Protein
HQ395_15965	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
HQ395_15985	COG4565	transcriptional regulatory protein
HQ395_15990	COG3290	protein histidine kinase activity
HQ395_15995	COG1846	Transcriptional regulator
HQ395_15995	COG1940	carbohydrate kinase activity
HQ395_16000	COG0840	transmembrane signaling receptor activity
HQ395_16005	COG3012	SEC-C Motif Domain Protein
HQ395_16015	COG3075	Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses fumarate or nitrate as electron acceptor
HQ395_16020	COG0247	lactate metabolic process
HQ395_16030	COG5433	transposase activity
HQ395_16040	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
HQ395_16045	COG0437	4 iron, 4 sulfur cluster binding
HQ395_16050	COG3301	Polysulphide reductase, NrfD
HQ395_16055	COG1138	Cytochrome C-type biogenesis protein
HQ395_16060	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
HQ395_16065	COG4235	cytochrome complex assembly
HQ395_16065	COG3088	subunit of a heme lyase
HQ395_16070	COG1051	belongs to the nudix hydrolase family
HQ395_16080	COG3033	Beta-eliminating lyase
HQ395_16090	COG3046	protein related to deoxyribodipyrimidine photolyase
HQ395_16095	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
HQ395_16130	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
HQ395_16135	COG0583	DNA-binding transcription factor activity
HQ395_16145	COG1335	isochorismatase
HQ395_16165	COG4774	siderophore transport
HQ395_16180	COG0583	DNA-binding transcription factor activity
HQ395_16185	COG2910	NAD(P)H-binding
HQ395_16195	COG0626	cystathionine gamma-synthase activity
HQ395_16200	COG0612	Peptidase, M16
HQ395_16205	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
HQ395_16215	COG1944	ATP diphosphatase activity
HQ395_16220	COG2116	formate transmembrane transporter activity
HQ395_16225	COG1882	Formate acetyltransferase
HQ395_16230	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
HQ395_16235	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
HQ395_16240	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
HQ395_16250	COG1840	ABC-type Fe3 transport system, periplasmic component
HQ395_16255	COG3842	ATPase activity
HQ395_16265	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
HQ395_16270	COG2983	Belongs to the UPF0260 family
HQ395_16280	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
HQ395_16285	COG0045	succinate-CoA ligase (ADP-forming) activity
HQ395_16290	COG0508	dehydrogenase complex catalyzes the overall conversion of
HQ395_16295	COG0567	Dehydrogenase, E1 component
HQ395_16305	COG1053	succinate dehydrogenase
HQ395_16310	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
HQ395_16335	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
HQ395_16340	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
HQ395_16340	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
HQ395_16350	COG3069	C4-dicarboxylate transmembrane transporter activity
HQ395_16365	COG1451	nucleotide metabolic process
HQ395_16380	COG0254	rRNA binding
HQ395_16385	COG0257	Belongs to the bacterial ribosomal protein bL36 family
HQ395_16395	COG0583	DNA-binding transcription factor activity
HQ395_16405	COG1172	Belongs to the binding-protein-dependent transport system permease family
HQ395_16415	COG1879	ABC-type sugar transport system periplasmic component
HQ395_16420	COG1069	ribulokinase activity
HQ395_16430	COG2160	L-arabinose isomerase activity
HQ395_16475	COG2916	Histone family protein nucleoid-structuring protein H-NS
HQ395_16550	COG3039	Transposase
HQ395_16565	COG0305	Participates in initiation and elongation during chromosome replication
HQ395_16605	COG1484	DNA-dependent DNA replication
HQ395_16610	COG4584	PFAM Integrase catalytic
HQ395_16645	COG0582	viral genome integration into host DNA
HQ395_16650	COG2925	Exonuclease
HQ395_16660	COG3345	alpha-galactosidase
HQ395_16665	COG1380	Effector of murein hydrolase LrgA
HQ395_16670	COG1346	cytolysis
HQ395_16675	COG0295	cytidine deaminase activity
HQ395_16680	COG1022	Amp-dependent synthetase and ligase
HQ395_16695	COG0861	Integral membrane protein TerC family
HQ395_16700	COG2885	chlorophyll binding
HQ395_16705	COG2199	diguanylate cyclase activity
HQ395_16725	COG2154	pterin-4-alpha-carbinolamine dehydratase
HQ395_16735	COG3768	UPF0283 membrane protein
HQ395_16740	COG3106	COG3106 Predicted ATPase
HQ395_16755	COG1842	Phage shock protein A
HQ395_16760	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
HQ395_16770	COG4168	peptide transport system, permease
HQ395_16775	COG4171	peptide transport system, permease
HQ395_16785	COG4172	Belongs to the ABC transporter superfamily
HQ395_16795	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
HQ395_16800	COG1286	toxin biosynthetic process
HQ395_16805	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
HQ395_16810	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
HQ395_16815	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
HQ395_16820	COG1674	ftsk spoiiie
HQ395_16820	COG0531	amino acid
HQ395_16830	COG0686	Belongs to the AlaDH PNT family
HQ395_16835	COG0492	ferredoxin-NADP+ reductase activity
HQ395_16840	COG3706	GGDEF domain
HQ395_16845	COG3134	Outer membrane lipoprotein
HQ395_16850	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
HQ395_16855	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
HQ395_16860	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
HQ395_16865	COG0542	response to heat
HQ395_16870	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
HQ395_16875	COG1278	Cold shock
HQ395_16880	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
HQ395_16910	COG2226	methyltransferase
HQ395_16920	COG3250	beta-galactosidase activity
HQ395_16925	COG2223	nitrite transmembrane transporter activity
HQ395_16930	COG5433	transposase activity
HQ395_16940	COG3039	Transposase
HQ395_16960	COG5433	transposase activity
HQ395_16965	COG3039	Transposase
HQ395_16970	COG1609	Transcriptional regulator
HQ395_16975	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
HQ395_16980	COG1085	galactose-1-phosphate uridylyltransferase
HQ395_16985	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
HQ395_16990	COG0469	pyruvate kinase activity
HQ395_17030	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HQ395_17035	COG0501	Belongs to the peptidase M48B family
HQ395_17055	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
HQ395_17065	COG0542	response to heat
HQ395_17070	COG0071	Belongs to the small heat shock protein (HSP20) family
HQ395_17135	COG4584	PFAM Integrase catalytic
HQ395_17140	COG1484	DNA-dependent DNA replication
HQ395_17220	COG3550	peptidyl-serine autophosphorylation
HQ395_17270	COG3829	transcription factor binding
HQ395_17350	COG5433	transposase activity
HQ395_17385	COG4584	PFAM Integrase catalytic
HQ395_17390	COG1484	DNA-dependent DNA replication
HQ395_17430	COG3501	Rhs element vgr protein
HQ395_17460	COG1435	thymidine kinase activity
HQ395_17465	COG1757	Na H antiporter
HQ395_17470	COG2916	Histone family protein nucleoid-structuring protein H-NS
HQ395_17475	COG2096	Adenosyltransferase
HQ395_17480	COG3530	Putative quorum-sensing-regulated virulence factor
HQ395_17485	COG0602	queuosine metabolic process
HQ395_17490	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
HQ395_17510	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
HQ395_17520	COG0776	regulation of translation
HQ395_17525	COG0539	negative regulation of cytoplasmic translation
HQ395_17530	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
HQ395_17535	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
HQ395_17545	COG0583	DNA-binding transcription factor activity
HQ395_17565	COG0778	Nitroreductase
HQ395_17570	COG5001	Diguanylate cyclase
HQ395_17570	COG3300	MHYT domain
HQ395_17580	COG0583	DNA-binding transcription factor activity
HQ395_17585	COG3437	response regulator, receiver
HQ395_17610	COG4989	oxidoreductase activity
HQ395_17615	COG0724	RNA recognition motif
HQ395_17635	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
HQ395_17650	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
HQ395_17655	COG1360	Flagellar Motor Protein
HQ395_17660	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
HQ395_17665	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
HQ395_17670	COG0649	NAD binding
HQ395_17670	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
HQ395_17685	COG1034	ATP synthesis coupled electron transport
HQ395_17690	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
HQ395_17695	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
HQ395_17700	COG0839	Belongs to the complex I subunit 6 family
HQ395_17705	COG0713	ATP synthesis coupled electron transport
HQ395_17715	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
HQ395_17720	COG1007	ATP synthesis coupled electron transport
HQ395_17735	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
HQ395_17735	COG2199	diguanylate cyclase activity
HQ395_17740	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HQ395_17740	COG0047	phosphoribosylformylglycinamidine synthase activity
HQ395_17745	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
HQ395_17750	COG1645	bacterial-type flagellum-dependent swarming motility
HQ395_17755	COG1160	GTP binding
HQ395_17760	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
HQ395_17765	COG2976	Protein conserved in bacteria
HQ395_17770	COG0124	histidyl-tRNA synthetase
HQ395_17775	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
HQ395_17790	COG0820	rRNA (adenine-C2-)-methyltransferase activity
HQ395_17795	COG0105	UTP biosynthetic process
HQ395_17800	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
HQ395_17810	COG0633	Ferredoxin
HQ395_17815	COG0443	Heat shock 70 kDa protein
HQ395_17820	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
HQ395_17830	COG0822	iron-sulfur transferase activity
HQ395_17835	COG1104	cysteine desulfurase activity
HQ395_17855	COG3154	lipid carrier protein
HQ395_17860	COG0826	peptidase U32
HQ395_17865	COG0826	peptidase U32
HQ395_17880	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
HQ395_17885	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
HQ395_17890	COG1862	Preprotein translocase
HQ395_17895	COG0343	queuine tRNA-ribosyltransferase activity
HQ395_17900	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
HQ395_17905	COG0517	IMP dehydrogenase activity
HQ395_17915	COG3634	alkyl hydroperoxide reductase activity
HQ395_17935	COG1393	Belongs to the ArsC family
HQ395_17940	COG0798	PFAM Bile acid sodium symporter
HQ395_17945	COG0640	Transcriptional regulator
HQ395_17950	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
HQ395_17950	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
HQ395_17955	COG0509	glycine decarboxylation via glycine cleavage system
HQ395_17960	COG0404	The glycine cleavage system catalyzes the degradation of glycine
HQ395_17970	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
HQ395_17990	COG2814	Major facilitator Superfamily
HQ395_17995	COG0625	glutathione transferase activity
HQ395_18005	COG0483	inositol monophosphate 1-phosphatase activity
HQ395_18025	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
HQ395_18040	COG1086	Polysaccharide biosynthesis protein
HQ395_18045	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
HQ395_18060	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
HQ395_18070	COG2089	acid synthase
HQ395_18075	COG4310	Domain of unknown function (DUF2172)
HQ395_18125	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
HQ395_18145	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HQ395_18145	COG0301	tRNA thio-modification
HQ395_18155	COG4953	penicillin-binding protein 1C
HQ395_18160	COG2373	Large extracellular alpha-helical protein
HQ395_18165	COG0446	pyridine nucleotide-disulphide oxidoreductase
HQ395_18175	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HQ395_18195	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HQ395_18205	COG2431	L-lysine efflux transmembrane transporter activity
HQ395_18210	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
HQ395_18215	COG3124	Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP
HQ395_18230	COG1393	Belongs to the ArsC family
HQ395_18240	COG4783	chaperone-mediated protein folding
HQ395_18245	COG0425	Belongs to the sulfur carrier protein TusA family
HQ395_18270	COG3842	ATPase activity
HQ395_18275	COG3833	ABC-type maltose transport systems, permease component
HQ395_18280	COG1175	transmembrane transport
HQ395_18290	COG3081	Nucleoid-associated protein
HQ395_18295	COG3082	Protein of unknown function (DUF1414)
HQ395_18300	COG3083	sulfuric ester hydrolase activity
HQ395_18305	COG4771	TonB-dependent receptor
HQ395_18310	COG1770	oligopeptidase
HQ395_18330	COG4574	serine-type endopeptidase inhibitor activity
HQ395_18335	COG3085	chromosome segregation
HQ395_18340	COG0583	DNA-binding transcription factor activity
HQ395_18345	COG0287	Prephenate dehydrogenase
HQ395_18345	COG1605	Chorismate mutase
HQ395_18350	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
HQ395_18355	COG0584	glycerophosphoryl diester phosphodiesterase
HQ395_18370	COG1349	DNA-binding transcription factor activity
HQ395_18375	COG2271	Major facilitator Superfamily
HQ395_18380	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
HQ395_18385	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
HQ395_18390	COG0583	DNA-binding transcription factor activity
HQ395_18410	COG0656	L-ascorbic acid biosynthetic process
HQ395_18415	COG2814	Major facilitator Superfamily
HQ395_18425	COG1294	oxidase, subunit
HQ395_18430	COG1271	oxidase subunit
HQ395_18435	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HQ395_18450	COG2979	Protein of unknown function (DUF533)
HQ395_18475	COG2271	Major facilitator Superfamily
HQ395_18480	COG0583	DNA-binding transcription factor activity
HQ395_18490	COG2807	transmembrane transport
HQ395_18495	COG1187	pseudouridine synthase activity
HQ395_18510	COG0346	lactoylglutathione lyase activity
HQ395_18520	COG1061	Type III restriction enzyme res subunit
HQ395_18535	COG3681	Belongs to the UPF0597 family
HQ395_18545	COG0814	amino acid
HQ395_18565	COG1166	arginine decarboxylase activity
HQ395_18575	COG2195	Cleaves the N-terminal amino acid of tripeptides
HQ395_18605	COG0583	DNA-binding transcription factor activity
HQ395_18615	COG2759	Belongs to the formate--tetrahydrofolate ligase family
HQ395_18620	COG0840	transmembrane signaling receptor activity
HQ395_18625	COG0302	gtp cyclohydrolase
HQ395_18635	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
HQ395_18660	COG2267	carboxylic ester hydrolase activity
HQ395_18665	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
HQ395_18680	COG0314	molybdopterin synthase activity
HQ395_18685	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
HQ395_18690	COG0315	cyclic pyranopterin monophosphate synthase activity
HQ395_18695	COG0521	Mo-molybdopterin cofactor biosynthetic process
HQ395_18700	COG3005	denitrification pathway
HQ395_18710	COG0348	domain, Protein
HQ395_18715	COG0437	4 iron, 4 sulfur cluster binding
HQ395_18720	COG0243	molybdopterin cofactor binding
HQ395_18730	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
HQ395_18730	COG1149	4fe-4S ferredoxin, iron-sulfur binding domain protein
HQ395_18735	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
HQ395_18740	COG3850	Histidine kinase
HQ395_18745	COG2197	response regulator
HQ395_18775	COG0121	glutamine amidotransferase
HQ395_18780	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
HQ395_18785	COG1960	acyl-CoA dehydrogenase activity
HQ395_18790	COG3437	response regulator, receiver
HQ395_18790	COG0784	Response regulator, receiver
HQ395_18805	COG0328	RNA-DNA hybrid ribonuclease activity
HQ395_18810	COG2226	methyltransferase
HQ395_18815	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
HQ395_18825	COG3021	interspecies interaction between organisms
HQ395_18835	COG1607	acyl-coa hydrolase
HQ395_18850	COG0741	lytic transglycosylase activity
HQ395_18860	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
HQ395_18880	COG2911	Protein conserved in bacteria
HQ395_18885	COG0729	surface antigen
HQ395_18895	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
HQ395_18900	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HQ395_18910	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
HQ395_18920	COG4134	Bacterial extracellular solute-binding protein
HQ395_18930	COG4136	ATPase activity
HQ395_18935	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HQ395_18940	COG2951	lytic endotransglycosylase activity
HQ395_18945	COG1846	Transcriptional regulator
HQ395_18955	COG0033	Phosphoglucomutase
HQ395_18960	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
HQ395_18965	COG0596	Alpha beta hydrolase
HQ395_18980	COG0716	FMN binding
HQ395_18990	COG0735	belongs to the Fur family
HQ395_18995	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
HQ395_19005	COG1263	PTS System
HQ395_19005	COG2190	(PTS) system
HQ395_19005	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HQ395_19010	COG0363	glucosamine-6-phosphate deaminase activity
HQ395_19015	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
HQ395_19020	COG1846	Transcriptional regulator
HQ395_19020	COG1940	carbohydrate kinase activity
HQ395_19025	COG2194	sulfuric ester hydrolase activity
HQ395_19030	COG0217	transcriptional regulatory protein
HQ395_19035	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
HQ395_19040	COG1801	Protein of unknown function DUF72
HQ395_19045	COG4106	trans-aconitate 2-methyltransferase activity
HQ395_19050	COG0500	methyltransferase
HQ395_19070	COG0450	alkyl hydroperoxide reductase
HQ395_19075	COG0583	DNA-binding transcription factor activity
HQ395_19085	COG0791	NLP P60 protein
HQ395_19100	COG1309	transcriptional regulator
HQ395_19140	COG0534	Mate efflux family protein
HQ395_19160	COG2366	antibiotic biosynthetic process
HQ395_19165	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
HQ395_19165	COG0674	pyruvate-flavodoxin oxidoreductase activity
HQ395_19165	COG1013	pyruvate-flavodoxin oxidoreductase activity
HQ395_19165	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
HQ395_19175	COG0633	Ferredoxin
HQ395_19175	COG3217	Mosc domain protein beta barrel domain protein
HQ395_19175	COG0633	Ferredoxin
HQ395_19175	COG3217	Mosc domain protein beta barrel domain protein
HQ395_19185	COG0501	Belongs to the peptidase M48B family
HQ395_19190	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
HQ395_19195	COG1073	alpha beta
HQ395_19195	COG2226	methyltransferase
HQ395_19200	COG0156	8-amino-7-oxononanoate synthase activity
HQ395_19205	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
HQ395_19225	COG0017	Asparaginyl-tRNA synthetase
HQ395_19230	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
HQ395_19255	COG0583	DNA-binding transcription factor activity
HQ395_19260	COG1393	Belongs to the ArsC family
HQ395_19265	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
HQ395_19270	COG1876	peptidase activity
HQ395_19280	COG3263	regulation of cellular component size
HQ395_19290	COG3263	regulation of cellular component size
HQ395_19300	COG1280	lysine exporter protein (LysE YggA)
HQ395_19340	COG1454	alcohol dehydrogenase
HQ395_19345	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
HQ395_19350	COG0702	epimerase
HQ395_19355	COG2914	Belongs to the UPF0125 (RnfH) family
HQ395_19360	COG2867	negative regulation of translational initiation
HQ395_19365	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
HQ395_19375	COG0582	viral genome integration into host DNA
HQ395_19385	COG3385	transposase activity
HQ395_19450	COG0625	glutathione transferase activity
HQ395_19455	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HQ395_19510	COG5377	YqaJ viral recombinase family
HQ395_19565	COG2003	Belongs to the UPF0758 family
HQ395_19620	COG1715	Restriction endonuclease
HQ395_19630	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
HQ395_19660	COG4804	nuclease activity
HQ395_19685	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HQ395_19755	COG4397	Mu-like prophage major head subunit gpT
HQ395_19760	COG4388	Caudovirus prohead serine protease
HQ395_19780	COG4383	Mu-like prophage protein gp29
HQ395_19785	COG4373	Mu-like prophage FluMu protein gp28
HQ395_19800	COG0640	Transcriptional regulator
HQ395_19925	COG0732	type I restriction modification DNA specificity domain
HQ395_19930	COG3171	Protein conserved in bacteria
HQ395_19940	COG0583	DNA-binding transcription factor activity
HQ395_19945	COG2610	gluconate transmembrane transporter activity
HQ395_19950	COG3048	D-serine ammonia-lyase activity
HQ395_19960	COG0538	isocitrate dehydrogenase activity
HQ395_19965	COG2207	Transcriptional regulator
HQ395_19985	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HQ395_20000	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
HQ395_20005	COG1263	PTS System
HQ395_20005	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HQ395_20010	COG1609	Transcriptional regulator
HQ395_20025	COG0456	acetyltransferase
HQ395_20040	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HQ395_20040	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HQ395_20040	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
HQ395_20045	COG5599	Phosphatase
HQ395_20060	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HQ395_20070	COG1187	pseudouridine synthase activity
HQ395_20080	COG0482	sulfurtransferase activity
HQ395_20085	COG2915	High frequency lysogenization protein hflD homolog
HQ395_20090	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
HQ395_20095	COG2850	peptidyl-arginine hydroxylation
HQ395_20100	COG3153	acetyltransferase
HQ395_20110	COG0625	glutathione transferase activity
HQ395_20115	COG0259	pyridoxamine-phosphate oxidase activity
HQ395_20130	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
HQ395_20130	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
HQ395_20135	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
HQ395_20150	COG3088	subunit of a heme lyase
HQ395_20150	COG4235	cytochrome complex assembly
HQ395_20155	COG3088	subunit of a heme lyase
HQ395_20155	COG4235	cytochrome complex assembly
HQ395_20160	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
HQ395_20165	COG1138	Cytochrome C-type biogenesis protein
HQ395_20170	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
HQ395_20175	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
HQ395_20180	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
HQ395_20185	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
HQ395_20200	COG0835	chemotaxis
HQ395_20210	COG1192	Involved in chromosome partitioning
HQ395_20215	COG1360	Flagellar Motor Protein
HQ395_20220	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
HQ395_20225	COG2201	protein-glutamate methylesterase activity
HQ395_20230	COG0643	Histidine kinase
HQ395_20230	COG0784	Response regulator, receiver
HQ395_20230	COG2198	Histidine kinase
HQ395_20235	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
HQ395_20260	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
HQ395_20270	COG1684	flagellar biosynthetic protein fliR
HQ395_20325	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
HQ395_20335	COG1677	Flagellar hook-basal body complex protein FliE
HQ395_20350	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
HQ395_20370	COG1737	Transcriptional regulator
HQ395_20375	COG0469	pyruvate kinase activity
HQ395_20385	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HQ395_20390	COG1960	acyl-CoA dehydrogenase activity
HQ395_20400	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
HQ395_20470	COG0243	molybdopterin cofactor binding
HQ395_20475	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
HQ395_20480	COG0583	DNA-binding transcription factor activity
HQ395_20490	COG1376	ErfK ybiS ycfS ynhG family protein
HQ395_20490	COG1388	LysM domain
HQ395_20505	COG3129	Specifically methylates the adenine in position 1618 of 23S rRNA
HQ395_20510	COG0791	NLP P60 protein
HQ395_20520	COG3118	belongs to the thioredoxin family
HQ395_20530	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
HQ395_20535	COG0788	formyltetrahydrofolate deformylase activity
HQ395_20545	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HQ395_20565	COG0366	Alpha amylase catalytic
HQ395_20570	COG0739	heme binding
HQ395_20570	COG0741	lytic transglycosylase activity
HQ395_20570	COG1196	nuclear chromosome segregation
HQ395_20575	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
HQ395_20580	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
HQ395_20590	COG0673	inositol 2-dehydrogenase activity
HQ395_20610	COG3152	Membrane
HQ395_20635	COG1032	radical SAM domain protein
HQ395_20645	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HQ395_20650	COG1566	PFAM secretion protein HlyD family protein
HQ395_20660	COG1752	Esterase of the alpha-beta hydrolase superfamily
HQ395_20665	COG0733	neurotransmitter:sodium symporter activity
HQ395_20695	COG0281	malic enzyme
HQ395_20705	COG0534	Mate efflux family protein
HQ395_20720	COG2233	PERMEase
HQ395_20725	COG0095	Lipoate-protein ligase
HQ395_20730	COG1115	amino acid carrier protein
HQ395_20735	COG0019	diaminopimelate decarboxylase activity
HQ395_20745	COG0678	peroxiredoxin activity
HQ395_20755	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
HQ395_20775	COG1131	(ABC) transporter
HQ395_20780	COG0545	Peptidyl-prolyl cis-trans isomerase
HQ395_20800	COG3142	Participates in the control of copper homeostasis
HQ395_20825	COG5002	protein histidine kinase activity
HQ395_20830	COG0745	RESPONSE REGULATOR receiver
HQ395_20835	COG0346	lactoylglutathione lyase activity
HQ395_20840	COG1804	L-carnitine dehydratase bile acid-inducible protein F
HQ395_20845	COG1960	acyl-CoA dehydrogenase activity
HQ395_20850	COG3284	Transcriptional regulator
HQ395_20865	COG0697	spore germination
HQ395_20870	COG4565	transcriptional regulatory protein
HQ395_20875	COG3290	protein histidine kinase activity
HQ395_20880	COG0281	malic enzyme
HQ395_20890	COG5433	transposase activity
HQ395_20900	COG1846	Transcriptional regulator
HQ395_20905	COG1566	PFAM secretion protein HlyD family protein
HQ395_20935	COG0602	queuosine metabolic process
HQ395_20940	COG1328	CTP reductase activity
HQ395_20950	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
HQ395_20955	COG3115	cell septum assembly
HQ395_20970	COG2860	membrane
HQ395_20980	COG3108	Peptidase M15
HQ395_20985	COG2989	Protein conserved in bacteria
HQ395_21000	COG0463	Glycosyl transferase, family 2
HQ395_21020	COG0366	Alpha amylase catalytic
HQ395_21060	COG3706	GGDEF domain
HQ395_21070	COG3590	peptidase
HQ395_21080	COG0488	(ABC) transporter
HQ395_21090	COG0531	amino acid
HQ395_21105	COG0814	amino acid
HQ395_21120	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
HQ395_21125	COG1982	Orn Lys Arg decarboxylase major
HQ395_21130	COG0531	amino acid
HQ395_21135	COG3710	Transcriptional regulator
HQ395_21140	COG0825	malonyl-CoA metabolic process
HQ395_21150	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HQ395_21155	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
HQ395_21160	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
HQ395_21165	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
HQ395_21170	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
HQ395_21185	COG0750	zinc metalloprotease
HQ395_21190	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
HQ395_21195	COG0575	Belongs to the CDS family
HQ395_21200	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
HQ395_21205	COG0233	cytoplasmic translational termination
HQ395_21210	COG0528	UMP kinase activity
HQ395_21215	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
HQ395_21220	COG0052	Belongs to the universal ribosomal protein uS2 family
HQ395_21225	COG0024	Methionine aminopeptidase
HQ395_21230	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
HQ395_21235	COG2171	N-acyltransferase activity
HQ395_21245	COG1263	PTS System
HQ395_21245	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HQ395_21255	COG4580	involved in the transport of maltose and maltodextrins
HQ395_21265	COG0564	pseudouridine synthase activity
HQ395_21270	COG3098	single-species biofilm formation
HQ395_21295	COG5595	Zn-ribbon-containing, possibly nucleic-acid-binding protein (DUF2310)
HQ395_21305	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
HQ395_21305	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
HQ395_21320	COG1611	Belongs to the LOG family
HQ395_21325	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HQ395_21330	COG0473	3-isopropylmalate dehydrogenase activity
HQ395_21340	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
HQ395_21345	COG2363	Small membrane protein
HQ395_21355	COG0583	DNA-binding transcription factor activity
HQ395_21360	COG0840	transmembrane signaling receptor activity
HQ395_21365	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HQ395_21380	COG1477	protein flavinylation
HQ395_21385	COG2871	sodium ion transport
HQ395_21390	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
HQ395_21395	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
HQ395_21400	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
HQ395_21405	COG1805	sodium ion transport
HQ395_21410	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
HQ395_21415	COG0271	Belongs to the BolA IbaG family
HQ395_21420	COG2813	Specifically methylates the guanine in position
HQ395_21430	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
HQ395_21440	COG2211	Major facilitator Superfamily
HQ395_21445	COG3248	Nucleoside-binding outer membrane protein
HQ395_21450	COG1666	GTP binding
HQ395_21455	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HQ395_21460	COG0693	protein deglycase activity
HQ395_21510	COG4104	PAAR repeat-containing protein
HQ395_21525	COG2771	luxR family
HQ395_21535	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
HQ395_21535	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
HQ395_21540	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
HQ395_21550	COG1151	hydroxylamine reductase activity
HQ395_21555	COG0783	Belongs to the Dps family
HQ395_21580	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
HQ395_21595	COG4221	oxidoreductase activity
HQ395_21605	COG0415	Belongs to the DNA photolyase family
HQ395_21610	COG0789	Transcriptional regulator
HQ395_21615	COG3272	Protein of unknown function (DUF1722)
HQ395_21645	COG1605	Chorismate mutase
HQ395_21645	COG0077	Prephenate dehydratase
HQ395_21680	COG0840	transmembrane signaling receptor activity
HQ395_21690	COG0300	oxidoreductase activity
HQ395_21715	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
HQ395_21745	COG0826	peptidase U32
HQ395_21750	COG1280	lysine exporter protein (LysE YggA)
HQ395_21760	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HQ395_21765	COG0840	transmembrane signaling receptor activity
HQ395_21780	COG2198	Histidine kinase
HQ395_21780	COG0643	Histidine kinase
HQ395_21790	COG0835	chemotaxis
HQ395_21795	COG0840	transmembrane signaling receptor activity
HQ395_21805	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
HQ395_21810	COG2201	protein-glutamate methylesterase activity
HQ395_21815	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
HQ395_21840	COG2205	protein histidine kinase activity
HQ395_21840	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HQ395_21845	COG2197	response regulator
HQ395_21870	COG2199	diguanylate cyclase activity
HQ395_21870	COG2200	EAL domain
HQ395_21870	COG2203	Gaf domain
HQ395_21875	COG0826	peptidase U32
HQ395_21880	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
HQ395_21885	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HQ395_21890	COG0305	Participates in initiation and elongation during chromosome replication
HQ395_21900	COG2200	EAL domain
HQ395_21905	COG0737	Belongs to the 5'-nucleotidase family
HQ395_21925	COG2204	response regulator
HQ395_21930	COG0545	Peptidyl-prolyl cis-trans isomerase
HQ395_21940	COG2900	Belongs to the SlyX family
HQ395_21945	COG1047	Peptidyl-prolyl cis-trans
HQ395_21950	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
HQ395_21960	COG0835	chemotaxis
HQ395_21960	COG0784	Response regulator, receiver
HQ395_21965	COG0429	hydrolase of the alpha beta-hydrolase fold
HQ395_21970	COG3706	GGDEF domain
HQ395_21970	COG5001	Diguanylate cyclase
HQ395_21970	COG4251	negative regulation of phosphorylation
HQ395_21970	COG2203	Gaf domain
HQ395_21975	COG3089	Belongs to the UPF0270 family
HQ395_21985	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
HQ395_21990	COG0463	Glycosyl transferase, family 2
HQ395_21995	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
HQ395_21995	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
HQ395_22000	COG0726	polysaccharide deacetylase
HQ395_22005	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
HQ395_22010	COG2076	Multidrug Resistance protein
HQ395_22015	COG2076	Multidrug Resistance protein
HQ395_22020	COG3954	Phosphoribulokinase
HQ395_22035	COG1765	OsmC-like protein
HQ395_22045	COG2226	methyltransferase
HQ395_22050	COG3397	chitin binding
HQ395_22065	COG2205	protein histidine kinase activity
HQ395_22065	COG2202	Pas domain
HQ395_22075	COG3655	Transcriptional regulator
HQ395_22080	COG2814	Major facilitator Superfamily
HQ395_22085	COG4771	TonB-dependent receptor
HQ395_22105	COG0748	coenzyme F420 binding
HQ395_22110	COG3721	Heme iron utilization protein
HQ395_22120	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HQ395_22145	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
HQ395_22150	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
HQ395_22155	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
HQ395_22175	COG0741	lytic transglycosylase activity
HQ395_22180	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
HQ395_22200	COG0488	(ABC) transporter
HQ395_22210	COG2252	PERMEase
HQ395_22215	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
HQ395_22220	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
HQ395_22225	COG3178	'Phosphotransferase
HQ395_22230	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
HQ395_22240	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
HQ395_22245	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
HQ395_22250	COG2967	ApaG domain
HQ395_22255	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
HQ395_22265	COG5433	transposase activity
HQ395_22275	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HQ395_22280	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
HQ395_22295	COG0318	PFAM AMP-dependent synthetase and ligase
HQ395_22300	COG3314	Sporulation integral membrane protein YlbJ
HQ395_22305	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
HQ395_22310	COG0211	Belongs to the bacterial ribosomal protein bL27 family
HQ395_22315	COG0261	This protein binds to 23S rRNA in the presence of protein L20
HQ395_22320	COG0142	geranyltranstransferase activity
HQ395_22325	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
HQ395_22330	COG0330	HflC and HflK could
HQ395_22335	COG0330	HflC and HflK could
HQ395_22340	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
HQ395_22345	COG1923	regulation of RNA biosynthetic process
HQ395_22350	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
HQ395_22355	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
HQ395_22365	COG0802	atpase or kinase
HQ395_22370	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
HQ395_22370	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
HQ395_22375	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
HQ395_22390	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
HQ395_22395	COG2011	ABC-type metal ion transport system permease component
HQ395_22400	COG1464	Belongs to the NlpA lipoprotein family
HQ395_22410	COG0840	transmembrane signaling receptor activity
HQ395_22455	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
HQ395_22470	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
HQ395_22475	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
HQ395_22485	COG2716	regulation of RNA biosynthetic process
HQ395_22490	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
HQ395_22495	COG3013	Belongs to the UPF0304 family
HQ395_22505	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HQ395_22510	COG0857	belongs to the CobB CobQ family
HQ395_22510	COG0280	phosphate acetyltransferase
HQ395_22520	COG0028	Belongs to the TPP enzyme family
HQ395_22530	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
HQ395_22535	COG0671	phosphoesterase, PA-phosphatase related
HQ395_22545	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
HQ395_22550	COG0473	3-isopropylmalate dehydrogenase activity
HQ395_22555	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
HQ395_22560	COG0066	3-isopropylmalate dehydratase activity
HQ395_22575	COG4143	(ABC) transporter
HQ395_22585	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
HQ395_22590	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
HQ395_22600	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HQ395_22630	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
HQ395_22635	COG0564	pseudouridine synthase activity
HQ395_22645	COG5001	Diguanylate cyclase
HQ395_22645	COG3300	MHYT domain
HQ395_22655	COG0459	protein refolding
HQ395_22660	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
HQ395_22670	COG3030	protein affecting phage T7 exclusion by the F plasmid
HQ395_22675	COG1027	Aspartate ammonia-lyase
HQ395_22680	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
HQ395_22690	COG0477	Major facilitator Superfamily
HQ395_22705	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HQ395_22720	COG0673	inositol 2-dehydrogenase activity
HQ395_22730	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
HQ395_22735	COG0635	Involved in the biosynthesis of porphyrin-containing compound
HQ395_22740	COG3036	rescue of stalled ribosome
HQ395_22745	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
HQ395_22755	COG0138	bifunctional purine biosynthesis protein purh
HQ395_22760	COG0151	Belongs to the GarS family
HQ395_22785	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HQ395_22790	COG0358	DNA primase activity
HQ395_22795	COG1610	YqeY-like protein
HQ395_22800	COG0828	Belongs to the bacterial ribosomal protein bS21 family
HQ395_22805	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
HQ395_22820	COG1238	metal cluster binding
HQ395_22825	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
HQ395_22830	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
HQ395_22835	COG0585	pseudouridine synthase activity
HQ395_22845	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
HQ395_22850	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
HQ395_22855	COG0148	phosphopyruvate hydratase activity
HQ395_22860	COG0504	CTP synthase activity
HQ395_22865	COG3956	TIGRFAM MazG family protein
HQ395_22870	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HQ395_22875	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HQ395_22885	COG4807	Protein conserved in bacteria
HQ395_22890	COG3023	N-Acetylmuramoyl-L-alanine amidase
HQ395_22895	COG1349	DNA-binding transcription factor activity
HQ395_22905	COG2222	sugar isomerase
HQ395_22910	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HQ395_22920	COG3716	PTS system mannose fructose sorbose family IID component
HQ395_22925	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
HQ395_22930	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
HQ395_22945	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
HQ395_22950	COG1381	Involved in DNA repair and RecF pathway recombination
HQ395_22960	COG0571	ribonuclease III activity
HQ395_22965	COG0681	Belongs to the peptidase S26 family
HQ395_22970	COG0481	GTPase activity
HQ395_22985	COG3073	An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E
HQ395_22990	COG1595	DNA-templated transcription, initiation
HQ395_22995	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
HQ395_23005	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
HQ395_23035	COG4232	protein-disulfide reductase activity
HQ395_23050	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
HQ395_23060	COG0126	phosphoglycerate kinase activity
HQ395_23065	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
HQ395_23070	COG1940	carbohydrate kinase activity
HQ395_23075	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
HQ395_23090	COG4991	sh3 domain protein
HQ395_23095	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
HQ395_23110	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
HQ395_23115	COG1028	Short-chain dehydrogenase reductase Sdr
HQ395_23125	COG2982	Protein involved in outer membrane biogenesis
HQ395_23130	COG1505	serine-type exopeptidase activity
HQ395_23135	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
HQ395_23140	COG0765	amino acid transport
HQ395_23145	COG0765	amino acid transport
HQ395_23150	COG1126	abc transporter atp-binding protein
HQ395_23155	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HQ395_23160	COG0577	efflux transmembrane transporter activity
HQ395_23160	COG1136	(ABC) transporter
HQ395_23165	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HQ395_23170	COG0745	RESPONSE REGULATOR receiver
HQ395_23180	COG2816	NAD+ diphosphatase activity
HQ395_23210	COG2070	2-Nitropropane dioxygenase
HQ395_23235	COG1912	Pfam S-adenosyl-l-methionine hydroxide adenosyltransferase
HQ395_23255	COG3706	GGDEF domain
HQ395_23260	COG0513	Belongs to the DEAD box helicase family
HQ395_23295	COG2957	Belongs to the agmatine deiminase family
HQ395_23310	COG1902	pentaerythritol trinitrate reductase activity
HQ395_23330	COG0456	acetyltransferase
HQ395_23340	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
HQ395_23360	COG0714	Associated with various cellular activities
HQ395_23380	COG1022	Amp-dependent synthetase and ligase
HQ395_23390	COG2918	glutathione biosynthetic process
HQ395_23395	COG0612	Peptidase, M16
HQ395_23400	COG1238	metal cluster binding
HQ395_23425	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
HQ395_23430	COG0359	binds to the 23S rRNA
HQ395_23435	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
HQ395_23440	COG0360	Binds together with S18 to 16S ribosomal RNA
HQ395_23445	COG1914	H( )-stimulated, divalent metal cation uptake system
HQ395_23465	COG2153	protein acetylation
HQ395_23475	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HQ395_23505	COG5433	transposase activity
HQ395_23510	COG0557	exoribonuclease II activity
HQ395_23515	COG3706	GGDEF domain
HQ395_23520	COG1854	S-ribosylhomocysteine lyase activity
HQ395_23535	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
HQ395_23535	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
HQ395_23595	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
HQ395_23600	COG1047	Peptidyl-prolyl cis-trans
HQ395_23605	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
HQ395_23610	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
HQ395_23615	COG0196	riboflavin kinase activity
HQ395_23625	COG0728	peptidoglycan biosynthetic process
HQ395_23630	COG0268	Binds directly to 16S ribosomal RNA
HQ395_23635	COG0640	Transcriptional regulator
HQ395_23640	COG0583	DNA-binding transcription factor activity
HQ395_23650	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
HQ395_23655	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
HQ395_23660	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
HQ395_23670	COG1051	belongs to the nudix hydrolase family
HQ395_23675	COG3066	DNA modification
HQ395_23685	COG0335	large ribosomal subunit rRNA binding
HQ395_23690	COG0336	Belongs to the RNA methyltransferase TrmD family
HQ395_23695	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
HQ395_23700	COG0228	four-way junction DNA binding
HQ395_23705	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
HQ395_23710	COG4137	Cytochrome C assembly protein
HQ395_23715	COG4536	flavin adenine dinucleotide binding
HQ395_23725	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
HQ395_23725	COG1017	nitric oxide dioxygenase activity
HQ395_23735	COG0039	L-malate dehydrogenase activity
HQ395_23740	COG4160	amino acid transport
HQ395_23745	COG4215	(ABC) transporter
HQ395_23750	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HQ395_23755	COG1126	abc transporter atp-binding protein
HQ395_23760	COG1438	arginine binding
HQ395_23765	COG2837	iron assimilation
HQ395_23770	COG3842	ATPase activity
HQ395_23780	COG1840	ABC-type Fe3 transport system, periplasmic component
HQ395_23785	COG0347	Belongs to the P(II) protein family
HQ395_23800	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
HQ395_23805	COG0583	DNA-binding transcription factor activity
HQ395_23820	COG1929	Belongs to the glycerate kinase type-1 family
HQ395_23825	COG2610	gluconate transmembrane transporter activity
HQ395_23830	COG3835	regulator
HQ395_23835	COG3112	Uncharacterised protein family (UPF0231)
HQ395_23850	COG0840	transmembrane signaling receptor activity
HQ395_23870	COG0513	Belongs to the DEAD box helicase family
HQ395_23910	COG1448	Aminotransferase
HQ395_23925	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HQ395_23930	COG1328	CTP reductase activity
HQ395_23950	COG0793	Belongs to the peptidase S41A family
HQ395_23950	COG4946	Tricorn protease homolog
HQ395_23980	COG0840	transmembrane signaling receptor activity
HQ395_23985	COG3397	chitin binding
HQ395_23990	COG0583	DNA-binding transcription factor activity
HQ395_23995	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
HQ395_24000	COG4208	sulfate ABC transporter
HQ395_24005	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
HQ395_24015	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
HQ395_24020	COG3174	membrane
HQ395_24025	COG0110	maltose O-acetyltransferase activity
HQ395_24060	COG0165	Argininosuccinate lyase
HQ395_24065	COG0137	argininosuccinate synthase activity
HQ395_24075	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
HQ395_24080	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
HQ395_24090	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
HQ395_24095	COG0460	homoserine dehydrogenase
HQ395_24095	COG0527	aspartate kinase activity
HQ395_24100	COG0626	cystathionine gamma-synthase activity
HQ395_24110	COG3708	Transcriptional regulator
HQ395_24110	COG2207	Transcriptional regulator
HQ395_24115	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HQ395_24120	COG0814	amino acid
HQ395_24125	COG1218	3'(2'),5'-bisphosphate nucleotidase
HQ395_24130	COG0494	nUDIX hydrolase
HQ395_24135	COG1011	Hydrolase
HQ395_24140	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
HQ395_24155	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
HQ395_24165	COG3156	type II secretion system protein K
HQ395_24175	COG4795	General secretion pathway protein
HQ395_24180	COG2165	general secretion pathway protein
HQ395_24195	COG2165	general secretion pathway protein
HQ395_24200	COG1459	type II secretion system