locus-tag	class	description
HQ396_00050	COG2816	NAD+ diphosphatase activity
HQ396_00060	COG0745	RESPONSE REGULATOR receiver
HQ396_00065	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HQ396_00070	COG0577	efflux transmembrane transporter activity
HQ396_00070	COG1136	(ABC) transporter
HQ396_00075	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HQ396_00080	COG1126	abc transporter atp-binding protein
HQ396_00090	COG0765	amino acid transport
HQ396_00140	COG4991	sh3 domain protein
HQ396_00155	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
HQ396_00160	COG1940	carbohydrate kinase activity
HQ396_00165	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
HQ396_00170	COG0126	phosphoglycerate kinase activity
HQ396_00180	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
HQ396_00215	COG0354	folic acid binding
HQ396_00220	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
HQ396_00230	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
HQ396_00235	COG1595	DNA-templated transcription, initiation
HQ396_00240	COG3073	An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E
HQ396_00255	COG0481	GTPase activity
HQ396_00260	COG0681	Belongs to the peptidase S26 family
HQ396_00265	COG0571	ribonuclease III activity
HQ396_00275	COG1381	Involved in DNA repair and RecF pathway recombination
HQ396_00280	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
HQ396_00295	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
HQ396_00300	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
HQ396_00305	COG3716	PTS system mannose fructose sorbose family IID component
HQ396_00315	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HQ396_00320	COG2222	sugar isomerase
HQ396_00330	COG1349	DNA-binding transcription factor activity
HQ396_00340	COG4807	Protein conserved in bacteria
HQ396_00355	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HQ396_00360	COG3956	TIGRFAM MazG family protein
HQ396_00365	COG0504	CTP synthase activity
HQ396_00370	COG0148	phosphopyruvate hydratase activity
HQ396_00380	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
HQ396_00390	COG0585	pseudouridine synthase activity
HQ396_00395	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
HQ396_00400	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
HQ396_00405	COG1238	metal cluster binding
HQ396_00420	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
HQ396_00425	COG0828	Belongs to the bacterial ribosomal protein bS21 family
HQ396_00430	COG1610	YqeY-like protein
HQ396_00435	COG0358	DNA primase activity
HQ396_00440	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HQ396_00480	COG0151	Belongs to the GarS family
HQ396_00485	COG0138	bifunctional purine biosynthesis protein purh
HQ396_00495	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
HQ396_00500	COG3036	rescue of stalled ribosome
HQ396_00505	COG0635	Involved in the biosynthesis of porphyrin-containing compound
HQ396_00510	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
HQ396_00520	COG0673	inositol 2-dehydrogenase activity
HQ396_00530	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HQ396_00550	COG0477	Major facilitator Superfamily
HQ396_00560	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
HQ396_00565	COG1027	Aspartate ammonia-lyase
HQ396_00570	COG3030	protein affecting phage T7 exclusion by the F plasmid
HQ396_00575	COG0534	Mate efflux family protein
HQ396_00580	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
HQ396_00585	COG0459	protein refolding
HQ396_00595	COG3300	MHYT domain
HQ396_00595	COG5001	Diguanylate cyclase
HQ396_00605	COG0564	pseudouridine synthase activity
HQ396_00610	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
HQ396_00650	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
HQ396_00660	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
HQ396_00685	COG0066	3-isopropylmalate dehydratase activity
HQ396_00690	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
HQ396_00695	COG0473	3-isopropylmalate dehydrogenase activity
HQ396_00700	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
HQ396_00710	COG0671	phosphoesterase, PA-phosphatase related
HQ396_00715	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
HQ396_00730	COG0857	belongs to the CobB CobQ family
HQ396_00730	COG0280	phosphate acetyltransferase
HQ396_00735	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HQ396_00745	COG3013	Belongs to the UPF0304 family
HQ396_00755	COG2716	regulation of RNA biosynthetic process
HQ396_00785	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
HQ396_00830	COG0840	transmembrane signaling receptor activity
HQ396_00845	COG2011	ABC-type metal ion transport system permease component
HQ396_00850	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
HQ396_00875	COG0802	atpase or kinase
HQ396_00890	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
HQ396_00895	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
HQ396_00900	COG1923	regulation of RNA biosynthetic process
HQ396_00905	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
HQ396_00910	COG0330	HflC and HflK could
HQ396_00915	COG0330	HflC and HflK could
HQ396_00920	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
HQ396_00925	COG0142	geranyltranstransferase activity
HQ396_00930	COG0261	This protein binds to 23S rRNA in the presence of protein L20
HQ396_00935	COG0211	Belongs to the bacterial ribosomal protein bL27 family
HQ396_00940	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
HQ396_00945	COG3314	Sporulation integral membrane protein YlbJ
HQ396_00950	COG0318	PFAM AMP-dependent synthetase and ligase
HQ396_00965	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
HQ396_00970	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HQ396_00980	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
HQ396_00985	COG2967	ApaG domain
HQ396_00990	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
HQ396_00995	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
HQ396_01005	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
HQ396_01010	COG3178	'Phosphotransferase
HQ396_01015	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
HQ396_01020	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
HQ396_01025	COG2252	PERMEase
HQ396_01035	COG0488	(ABC) transporter
HQ396_01055	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
HQ396_01060	COG0741	lytic transglycosylase activity
HQ396_01080	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
HQ396_01085	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
HQ396_01090	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
HQ396_01125	COG3721	Heme iron utilization protein
HQ396_01130	COG0748	coenzyme F420 binding
HQ396_01150	COG4771	TonB-dependent receptor
HQ396_01155	COG2814	Major facilitator Superfamily
HQ396_01160	COG3655	Transcriptional regulator
HQ396_01170	COG2202	Pas domain
HQ396_01170	COG2205	protein histidine kinase activity
HQ396_01190	COG2226	methyltransferase
HQ396_01200	COG1765	OsmC-like protein
HQ396_01215	COG3954	Phosphoribulokinase
HQ396_01220	COG2076	Multidrug Resistance protein
HQ396_01225	COG2076	Multidrug Resistance protein
HQ396_01230	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
HQ396_01235	COG0726	polysaccharide deacetylase
HQ396_01260	COG3089	Belongs to the UPF0270 family
HQ396_01265	COG5001	Diguanylate cyclase
HQ396_01265	COG4251	negative regulation of phosphorylation
HQ396_01265	COG3706	GGDEF domain
HQ396_01265	COG2203	Gaf domain
HQ396_01270	COG0429	hydrolase of the alpha beta-hydrolase fold
HQ396_01275	COG0784	Response regulator, receiver
HQ396_01275	COG0835	chemotaxis
HQ396_01285	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
HQ396_01290	COG1047	Peptidyl-prolyl cis-trans
HQ396_01305	COG0545	Peptidyl-prolyl cis-trans isomerase
HQ396_01310	COG2204	response regulator
HQ396_01335	COG2200	EAL domain
HQ396_01345	COG0305	Participates in initiation and elongation during chromosome replication
HQ396_01350	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HQ396_01355	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
HQ396_01360	COG0826	peptidase U32
HQ396_01365	COG2200	EAL domain
HQ396_01365	COG2203	Gaf domain
HQ396_01365	COG2199	diguanylate cyclase activity
HQ396_01390	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
HQ396_01395	COG2201	protein-glutamate methylesterase activity
HQ396_01400	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
HQ396_01410	COG0840	transmembrane signaling receptor activity
HQ396_01415	COG0835	chemotaxis
HQ396_01425	COG0643	Histidine kinase
HQ396_01425	COG2198	Histidine kinase
HQ396_01440	COG0840	transmembrane signaling receptor activity
HQ396_01445	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HQ396_01455	COG1280	lysine exporter protein (LysE YggA)
HQ396_01460	COG0826	peptidase U32
HQ396_01510	COG0300	oxidoreductase activity
HQ396_01520	COG0840	transmembrane signaling receptor activity
HQ396_01530	COG0235	Class ii aldolase
HQ396_01535	COG1454	alcohol dehydrogenase
HQ396_01540	COG4977	sequence-specific DNA binding
HQ396_01550	COG4806	L-rhamnose isomerase
HQ396_01560	COG3254	rhamnose metabolic process
HQ396_01590	COG1204	response to ionizing radiation
HQ396_01595	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HQ396_01630	COG0515	serine threonine protein kinase
HQ396_01630	COG2815	serine threonine protein kinase
HQ396_01645	COG2003	Belongs to the UPF0758 family
HQ396_01690	COG5377	YqaJ viral recombinase family
HQ396_01720	COG0077	Prephenate dehydratase
HQ396_01720	COG1605	Chorismate mutase
HQ396_01750	COG3272	Protein of unknown function (DUF1722)
HQ396_01755	COG0789	Transcriptional regulator
HQ396_01770	COG4221	oxidoreductase activity
HQ396_01810	COG0783	Belongs to the Dps family
HQ396_01815	COG1151	hydroxylamine reductase activity
HQ396_01825	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
HQ396_01830	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
HQ396_01830	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
HQ396_01840	COG2771	luxR family
HQ396_01855	COG4104	PAAR repeat-containing protein
HQ396_01900	COG0693	protein deglycase activity
HQ396_01905	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HQ396_01910	COG1666	GTP binding
HQ396_01915	COG3248	Nucleoside-binding outer membrane protein
HQ396_01920	COG2211	Major facilitator Superfamily
HQ396_01930	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
HQ396_01940	COG2813	Specifically methylates the guanine in position
HQ396_01945	COG0271	Belongs to the BolA IbaG family
HQ396_01950	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
HQ396_01955	COG1805	sodium ion transport
HQ396_01960	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
HQ396_01965	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
HQ396_01970	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
HQ396_01975	COG2871	sodium ion transport
HQ396_01980	COG1477	protein flavinylation
HQ396_01995	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HQ396_02000	COG0840	transmembrane signaling receptor activity
HQ396_02005	COG0583	DNA-binding transcription factor activity
HQ396_02015	COG2363	Small membrane protein
HQ396_02020	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
HQ396_02030	COG0473	3-isopropylmalate dehydrogenase activity
HQ396_02055	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
HQ396_02055	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
HQ396_02065	COG5595	Zn-ribbon-containing, possibly nucleic-acid-binding protein (DUF2310)
HQ396_02090	COG3098	single-species biofilm formation
HQ396_02095	COG0564	pseudouridine synthase activity
HQ396_02105	COG4580	involved in the transport of maltose and maltodextrins
HQ396_02115	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HQ396_02115	COG1263	PTS System
HQ396_02125	COG2171	N-acyltransferase activity
HQ396_02130	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
HQ396_02140	COG0052	Belongs to the universal ribosomal protein uS2 family
HQ396_02145	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
HQ396_02150	COG0528	UMP kinase activity
HQ396_02155	COG0233	cytoplasmic translational termination
HQ396_02160	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
HQ396_02165	COG0575	Belongs to the CDS family
HQ396_02170	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
HQ396_02175	COG0750	zinc metalloprotease
HQ396_02190	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
HQ396_02195	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
HQ396_02200	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
HQ396_02205	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
HQ396_02210	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HQ396_02220	COG0825	malonyl-CoA metabolic process
HQ396_02230	COG0531	amino acid
HQ396_02235	COG1982	Orn Lys Arg decarboxylase major
HQ396_02240	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
HQ396_02255	COG0814	amino acid
HQ396_02260	COG1234	tRNA 3'-trailer cleavage
HQ396_02270	COG0531	amino acid
HQ396_02290	COG3590	peptidase
HQ396_02300	COG3706	GGDEF domain
HQ396_02355	COG0463	Glycosyl transferase, family 2
HQ396_02370	COG2989	Protein conserved in bacteria
HQ396_02375	COG3108	Peptidase M15
HQ396_02405	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
HQ396_02415	COG1328	CTP reductase activity
HQ396_02420	COG0602	queuosine metabolic process
HQ396_02450	COG1566	PFAM secretion protein HlyD family protein
HQ396_02455	COG1846	Transcriptional regulator
HQ396_02495	COG0697	spore germination
HQ396_02530	COG0745	RESPONSE REGULATOR receiver
HQ396_02560	COG3142	Participates in the control of copper homeostasis
HQ396_02565	COG0545	Peptidyl-prolyl cis-trans isomerase
HQ396_02590	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
HQ396_02600	COG0678	peroxiredoxin activity
HQ396_02610	COG0019	diaminopimelate decarboxylase activity
HQ396_02640	COG0534	Mate efflux family protein
HQ396_02650	COG0281	malic enzyme
HQ396_02680	COG0733	neurotransmitter:sodium symporter activity
HQ396_02685	COG1752	Esterase of the alpha-beta hydrolase superfamily
HQ396_02695	COG1566	PFAM secretion protein HlyD family protein
HQ396_02700	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HQ396_02710	COG1032	radical SAM domain protein
HQ396_02740	COG0673	inositol 2-dehydrogenase activity
HQ396_02750	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
HQ396_02755	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
HQ396_02760	COG1196	nuclear chromosome segregation
HQ396_02760	COG0739	heme binding
HQ396_02760	COG0741	lytic transglycosylase activity
HQ396_02765	COG0366	Alpha amylase catalytic
HQ396_02795	COG0788	formyltetrahydrofolate deformylase activity
HQ396_02800	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
HQ396_02810	COG3118	belongs to the thioredoxin family
HQ396_02820	COG0791	NLP P60 protein
HQ396_02825	COG3129	Specifically methylates the adenine in position 1618 of 23S rRNA
HQ396_02840	COG1388	LysM domain
HQ396_02840	COG1376	ErfK ybiS ycfS ynhG family protein
HQ396_02850	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HQ396_02855	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HQ396_02860	COG0745	RESPONSE REGULATOR receiver
HQ396_02865	COG5002	protein histidine kinase activity
HQ396_02885	COG4869	propanediol catabolic process
HQ396_02895	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HQ396_02900	COG1882	Formate acetyltransferase
HQ396_02905	COG1012	belongs to the aldehyde dehydrogenase family
HQ396_02905	COG1454	alcohol dehydrogenase
HQ396_02950	COG0583	DNA-binding transcription factor activity
HQ396_02960	COG0243	molybdopterin cofactor binding
HQ396_02980	COG1960	acyl-CoA dehydrogenase activity
HQ396_02995	COG0469	pyruvate kinase activity
HQ396_03000	COG1737	Transcriptional regulator
HQ396_03035	COG1677	Flagellar hook-basal body complex protein FliE
HQ396_03045	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
HQ396_03100	COG1684	flagellar biosynthetic protein fliR
HQ396_03135	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
HQ396_03140	COG2198	Histidine kinase
HQ396_03140	COG0643	Histidine kinase
HQ396_03140	COG0784	Response regulator, receiver
HQ396_03145	COG2201	protein-glutamate methylesterase activity
HQ396_03150	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
HQ396_03155	COG1360	Flagellar Motor Protein
HQ396_03160	COG1192	Involved in chromosome partitioning
HQ396_03170	COG0835	chemotaxis
HQ396_03190	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
HQ396_03195	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
HQ396_03200	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
HQ396_03210	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
HQ396_03215	COG3088	subunit of a heme lyase
HQ396_03215	COG4235	cytochrome complex assembly
HQ396_03220	COG3088	subunit of a heme lyase
HQ396_03220	COG4235	cytochrome complex assembly
HQ396_03235	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
HQ396_03240	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
HQ396_03240	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
HQ396_03255	COG0259	pyridoxamine-phosphate oxidase activity
HQ396_03260	COG0625	glutathione transferase activity
HQ396_03270	COG3153	acetyltransferase
HQ396_03275	COG2850	peptidyl-arginine hydroxylation
HQ396_03280	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
HQ396_03285	COG2915	High frequency lysogenization protein hflD homolog
HQ396_03290	COG0482	sulfurtransferase activity
HQ396_03300	COG1187	pseudouridine synthase activity
HQ396_03310	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
HQ396_03310	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HQ396_03310	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HQ396_03325	COG5599	Phosphatase
HQ396_03330	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
HQ396_03330	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HQ396_03330	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HQ396_03340	COG0456	acetyltransferase
HQ396_03350	COG0789	Transcriptional regulator
HQ396_03360	COG1609	Transcriptional regulator
HQ396_03365	COG1263	PTS System
HQ396_03365	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HQ396_03385	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HQ396_03410	COG0538	isocitrate dehydrogenase activity
HQ396_03420	COG3048	D-serine ammonia-lyase activity
HQ396_03425	COG2610	gluconate transmembrane transporter activity
HQ396_03430	COG0583	DNA-binding transcription factor activity
HQ396_03450	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
HQ396_03455	COG2867	negative regulation of translational initiation
HQ396_03460	COG2914	Belongs to the UPF0125 (RnfH) family
HQ396_03470	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
HQ396_03485	COG0564	pseudouridine synthase activity
HQ396_03515	COG1280	lysine exporter protein (LysE YggA)
HQ396_03525	COG3263	regulation of cellular component size
HQ396_03535	COG3263	regulation of cellular component size
HQ396_03545	COG1876	peptidase activity
HQ396_03550	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
HQ396_03555	COG1393	Belongs to the ArsC family
HQ396_03560	COG0583	DNA-binding transcription factor activity
HQ396_03570	COG3069	C4-dicarboxylate transmembrane transporter activity
HQ396_03585	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
HQ396_03590	COG0017	Asparaginyl-tRNA synthetase
HQ396_03610	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
HQ396_03615	COG0156	8-amino-7-oxononanoate synthase activity
HQ396_03620	COG2226	methyltransferase
HQ396_03620	COG1073	alpha beta
HQ396_03625	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
HQ396_03640	COG0633	Ferredoxin
HQ396_03640	COG3217	Mosc domain protein beta barrel domain protein
HQ396_03640	COG0633	Ferredoxin
HQ396_03640	COG3217	Mosc domain protein beta barrel domain protein
HQ396_03650	COG0674	pyruvate-flavodoxin oxidoreductase activity
HQ396_03650	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
HQ396_03650	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
HQ396_03650	COG1013	pyruvate-flavodoxin oxidoreductase activity
HQ396_03730	COG0791	NLP P60 protein
HQ396_03740	COG0583	DNA-binding transcription factor activity
HQ396_03745	COG0450	alkyl hydroperoxide reductase
HQ396_03765	COG0500	methyltransferase
HQ396_03770	COG4106	trans-aconitate 2-methyltransferase activity
HQ396_03775	COG1801	Protein of unknown function DUF72
HQ396_03780	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
HQ396_03785	COG0217	transcriptional regulatory protein
HQ396_03795	COG1846	Transcriptional regulator
HQ396_03795	COG1940	carbohydrate kinase activity
HQ396_03800	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
HQ396_03805	COG0363	glucosamine-6-phosphate deaminase activity
HQ396_03810	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HQ396_03810	COG2190	(PTS) system
HQ396_03810	COG1263	PTS System
HQ396_03815	COG2190	(PTS) system
HQ396_03815	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HQ396_03815	COG1263	PTS System
HQ396_03825	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
HQ396_03830	COG0735	belongs to the Fur family
HQ396_03840	COG0716	FMN binding
HQ396_03855	COG0596	Alpha beta hydrolase
HQ396_03860	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
HQ396_03865	COG0033	Phosphoglucomutase
HQ396_03875	COG1846	Transcriptional regulator
HQ396_03885	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HQ396_03900	COG4134	Bacterial extracellular solute-binding protein
HQ396_03905	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
HQ396_03910	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
HQ396_03920	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HQ396_03925	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
HQ396_03935	COG0729	surface antigen
HQ396_03960	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
HQ396_03970	COG0741	lytic transglycosylase activity
HQ396_03985	COG1607	acyl-coa hydrolase
HQ396_03995	COG3021	interspecies interaction between organisms
HQ396_04000	COG3021	interspecies interaction between organisms
HQ396_04005	COG1388	LysM domain
HQ396_04005	COG0741	lytic transglycosylase activity
HQ396_04010	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
HQ396_04020	COG0328	RNA-DNA hybrid ribonuclease activity
HQ396_04035	COG0784	Response regulator, receiver
HQ396_04035	COG3437	response regulator, receiver
HQ396_04045	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
HQ396_04050	COG0121	glutamine amidotransferase
HQ396_04080	COG2197	response regulator
HQ396_04090	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
HQ396_04095	COG1149	4fe-4S ferredoxin, iron-sulfur binding domain protein
HQ396_04095	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
HQ396_04105	COG0243	molybdopterin cofactor binding
HQ396_04110	COG0437	4 iron, 4 sulfur cluster binding
HQ396_04115	COG0348	domain, Protein
HQ396_04125	COG3005	denitrification pathway
HQ396_04130	COG0521	Mo-molybdopterin cofactor biosynthetic process
HQ396_04135	COG0315	cyclic pyranopterin monophosphate synthase activity
HQ396_04140	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
HQ396_04145	COG0314	molybdopterin synthase activity
HQ396_04160	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
HQ396_04165	COG2267	carboxylic ester hydrolase activity
HQ396_04190	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
HQ396_04200	COG0302	gtp cyclohydrolase
HQ396_04205	COG0840	transmembrane signaling receptor activity
HQ396_04220	COG0583	DNA-binding transcription factor activity
HQ396_04250	COG2195	Cleaves the N-terminal amino acid of tripeptides
HQ396_04260	COG1166	arginine decarboxylase activity
HQ396_04280	COG0814	amino acid
HQ396_04290	COG3681	Belongs to the UPF0597 family
HQ396_04295	COG2964	Protein conserved in bacteria
HQ396_04315	COG0346	lactoylglutathione lyase activity
HQ396_04340	COG2807	transmembrane transport
HQ396_04350	COG0583	DNA-binding transcription factor activity
HQ396_04355	COG2271	Major facilitator Superfamily
HQ396_04370	COG1607	acyl-coa hydrolase
HQ396_04385	COG2979	Protein of unknown function (DUF533)
HQ396_04405	COG1294	oxidase, subunit
HQ396_04415	COG2814	Major facilitator Superfamily
HQ396_04420	COG0656	L-ascorbic acid biosynthetic process
HQ396_04450	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
HQ396_04455	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
HQ396_04460	COG2271	Major facilitator Superfamily
HQ396_04465	COG1349	DNA-binding transcription factor activity
HQ396_04475	COG0584	glycerophosphoryl diester phosphodiesterase
HQ396_04480	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
HQ396_04485	COG0287	Prephenate dehydrogenase
HQ396_04485	COG1605	Chorismate mutase
HQ396_04490	COG0583	DNA-binding transcription factor activity
HQ396_04495	COG3085	chromosome segregation
HQ396_04500	COG4574	serine-type endopeptidase inhibitor activity
HQ396_04535	COG3082	Protein of unknown function (DUF1414)
HQ396_04550	COG1175	transmembrane transport
HQ396_04560	COG3842	ATPase activity
HQ396_04590	COG4783	chaperone-mediated protein folding
HQ396_04600	COG1393	Belongs to the ArsC family
HQ396_04615	COG3124	Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP
HQ396_04620	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
HQ396_04625	COG2431	L-lysine efflux transmembrane transporter activity
HQ396_04655	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HQ396_04685	COG1538	Outer membrane efflux protein
HQ396_04690	COG0628	permease
HQ396_04700	COG4953	penicillin-binding protein 1C
HQ396_04710	COG0301	tRNA thio-modification
HQ396_04710	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HQ396_04730	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
HQ396_04760	COG2801	Transposase and inactivated derivatives
HQ396_04790	COG4310	Domain of unknown function (DUF2172)
HQ396_04795	COG2089	acid synthase
HQ396_04805	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
HQ396_04840	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
HQ396_04860	COG0483	inositol monophosphate 1-phosphatase activity
HQ396_04870	COG0625	glutathione transferase activity
HQ396_04900	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
HQ396_04905	COG0404	The glycine cleavage system catalyzes the degradation of glycine
HQ396_04910	COG0509	glycine decarboxylation via glycine cleavage system
HQ396_04915	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
HQ396_04915	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
HQ396_04925	COG0641	radical SAM
HQ396_04930	COG0640	Transcriptional regulator
HQ396_04935	COG0798	PFAM Bile acid sodium symporter
HQ396_04940	COG1393	Belongs to the ArsC family
HQ396_04960	COG3634	alkyl hydroperoxide reductase activity
HQ396_04970	COG0517	IMP dehydrogenase activity
HQ396_04975	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
HQ396_04980	COG0343	queuine tRNA-ribosyltransferase activity
HQ396_04985	COG1862	Preprotein translocase
HQ396_04990	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
HQ396_04995	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
HQ396_05010	COG0826	peptidase U32
HQ396_05015	COG0826	peptidase U32
HQ396_05020	COG3154	lipid carrier protein
HQ396_05040	COG1104	cysteine desulfurase activity
HQ396_05045	COG0822	iron-sulfur transferase activity
HQ396_05055	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
HQ396_05060	COG0443	Heat shock 70 kDa protein
HQ396_05065	COG0633	Ferredoxin
HQ396_05075	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
HQ396_05080	COG0105	UTP biosynthetic process
HQ396_05085	COG0820	rRNA (adenine-C2-)-methyltransferase activity
HQ396_05100	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
HQ396_05105	COG0124	histidyl-tRNA synthetase
HQ396_05110	COG2976	Protein conserved in bacteria
HQ396_05115	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
HQ396_05120	COG1160	GTP binding
HQ396_05125	COG1645	bacterial-type flagellum-dependent swarming motility
HQ396_05130	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
HQ396_05135	COG0047	phosphoribosylformylglycinamidine synthase activity
HQ396_05135	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HQ396_05140	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
HQ396_05140	COG2199	diguanylate cyclase activity
HQ396_05155	COG1007	ATP synthesis coupled electron transport
HQ396_05160	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
HQ396_05170	COG0713	ATP synthesis coupled electron transport
HQ396_05175	COG0839	Belongs to the complex I subunit 6 family
HQ396_05180	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
HQ396_05185	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
HQ396_05210	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
HQ396_05215	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
HQ396_05220	COG1360	Flagellar Motor Protein
HQ396_05225	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
HQ396_05245	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
HQ396_05265	COG0724	RNA recognition motif
HQ396_05295	COG3437	response regulator, receiver
HQ396_05300	COG0583	DNA-binding transcription factor activity
HQ396_05315	COG0778	Nitroreductase
HQ396_05345	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
HQ396_05350	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
HQ396_05355	COG0539	negative regulation of cytoplasmic translation
HQ396_05360	COG0776	regulation of translation
HQ396_05370	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
HQ396_05390	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
HQ396_05395	COG0602	queuosine metabolic process
HQ396_05400	COG3530	Putative quorum-sensing-regulated virulence factor
HQ396_05410	COG2916	Histone family protein nucleoid-structuring protein H-NS
HQ396_05420	COG1435	thymidine kinase activity
HQ396_05450	COG3501	Rhs element vgr protein
HQ396_05485	COG3209	COG3209 Rhs family protein
HQ396_05520	COG2801	Transposase and inactivated derivatives
HQ396_05600	COG3829	transcription factor binding
HQ396_05635	COG3179	chitinase
HQ396_05665	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
HQ396_05670	COG1278	Cold shock
HQ396_05675	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
HQ396_05680	COG0542	response to heat
HQ396_05685	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
HQ396_05690	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
HQ396_05695	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
HQ396_05700	COG3134	Outer membrane lipoprotein
HQ396_05705	COG3706	GGDEF domain
HQ396_05710	COG0492	ferredoxin-NADP+ reductase activity
HQ396_05715	COG0686	Belongs to the AlaDH PNT family
HQ396_05725	COG0531	amino acid
HQ396_05725	COG1674	ftsk spoiiie
HQ396_05730	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
HQ396_05735	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
HQ396_05740	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
HQ396_05745	COG1286	toxin biosynthetic process
HQ396_05750	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
HQ396_05760	COG4172	Belongs to the ABC transporter superfamily
HQ396_05770	COG4171	peptide transport system, permease
HQ396_05775	COG4168	peptide transport system, permease
HQ396_05790	COG1842	Phage shock protein A
HQ396_05805	COG3106	COG3106 Predicted ATPase
HQ396_05810	COG3768	UPF0283 membrane protein
HQ396_05840	COG2199	diguanylate cyclase activity
HQ396_05845	COG2885	chlorophyll binding
HQ396_05850	COG0861	Integral membrane protein TerC family
HQ396_05865	COG1022	Amp-dependent synthetase and ligase
HQ396_05870	COG0295	cytidine deaminase activity
HQ396_05880	COG1380	Effector of murein hydrolase LrgA
HQ396_05915	COG2188	Transcriptional regulator
HQ396_05925	COG1735	metal-dependent hydrolase with the TIM-barrel fold
HQ396_05940	COG3457	Alanine racemase
HQ396_05945	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
HQ396_05955	COG2160	L-arabinose isomerase activity
HQ396_05970	COG1879	ABC-type sugar transport system periplasmic component
HQ396_05990	COG0583	DNA-binding transcription factor activity
HQ396_06000	COG0257	Belongs to the bacterial ribosomal protein bL36 family
HQ396_06005	COG0254	rRNA binding
HQ396_06020	COG1451	nucleotide metabolic process
HQ396_06035	COG3069	C4-dicarboxylate transmembrane transporter activity
HQ396_06045	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
HQ396_06045	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
HQ396_06050	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
HQ396_06075	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
HQ396_06080	COG1053	succinate dehydrogenase
HQ396_06090	COG0567	Dehydrogenase, E1 component
HQ396_06095	COG0508	dehydrogenase complex catalyzes the overall conversion of
HQ396_06100	COG0045	succinate-CoA ligase (ADP-forming) activity
HQ396_06105	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
HQ396_06120	COG2983	Belongs to the UPF0260 family
HQ396_06135	COG3842	ATPase activity
HQ396_06140	COG1840	ABC-type Fe3 transport system, periplasmic component
HQ396_06150	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
HQ396_06160	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
HQ396_06165	COG1882	Formate acetyltransferase
HQ396_06170	COG2116	formate transmembrane transporter activity
HQ396_06175	COG1944	ATP diphosphatase activity
HQ396_06185	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
HQ396_06190	COG0612	Peptidase, M16
HQ396_06195	COG0626	cystathionine gamma-synthase activity
HQ396_06205	COG2910	NAD(P)H-binding
HQ396_06210	COG0583	DNA-binding transcription factor activity
HQ396_06220	COG4977	sequence-specific DNA binding
HQ396_06225	COG4774	siderophore transport
HQ396_06235	COG0583	DNA-binding transcription factor activity
HQ396_06240	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
HQ396_06250	COG0517	IMP dehydrogenase activity
HQ396_06250	COG0516	GMP reductase activity
HQ396_06265	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
HQ396_06270	COG3046	protein related to deoxyribodipyrimidine photolyase
HQ396_06280	COG3033	Beta-eliminating lyase
HQ396_06290	COG1051	belongs to the nudix hydrolase family
HQ396_06320	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
HQ396_06330	COG0247	lactate metabolic process
HQ396_06340	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
HQ396_06345	COG3012	SEC-C Motif Domain Protein
HQ396_06350	COG0840	transmembrane signaling receptor activity
HQ396_06355	COG1940	carbohydrate kinase activity
HQ396_06355	COG1846	Transcriptional regulator
HQ396_06360	COG3290	protein histidine kinase activity
HQ396_06365	COG4565	transcriptional regulatory protein
HQ396_06385	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
HQ396_06390	COG2985	domain, Protein
HQ396_06390	COG0569	domain protein
HQ396_06400	COG0556	nucleotide-excision repair
HQ396_06410	COG0586	Pfam SNARE associated Golgi protein
HQ396_06415	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
HQ396_06420	COG3067	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
HQ396_06425	COG2186	Transcriptional regulator
HQ396_06430	COG2719	SpoVR family
HQ396_06440	COG2766	serine protein kinase
HQ396_06445	COG0514	ATP-dependent DNA helicase (RecQ)
HQ396_06450	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
HQ396_06455	COG0814	amino acid
HQ396_06485	COG0058	SHG alpha-glucan phosphorylase activity
HQ396_06490	COG0471	metal ion transport
HQ396_06495	COG3118	belongs to the thioredoxin family
HQ396_06505	COG1132	(ABC) transporter
HQ396_06525	COG2501	S4 domain
HQ396_06535	COG3243	poly(R)-hydroxyalkanoic acid synthase
HQ396_06560	COG2329	Antibiotic biosynthesis monooxygenase
HQ396_06595	COG1742	UPF0060 membrane protein
HQ396_06605	COG0456	acetyltransferase
HQ396_06610	COG0513	Belongs to the DEAD box helicase family
HQ396_06615	COG0386	Belongs to the glutathione peroxidase family
HQ396_06625	COG1181	Belongs to the D-alanine--D-alanine ligase family
HQ396_06635	COG3148	PFAM DTW domain containing protein
HQ396_06640	COG0730	response to heat
HQ396_06645	COG0583	DNA-binding transcription factor activity
HQ396_06715	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
HQ396_06720	COG1011	Hydrolase
HQ396_06740	COG1434	Gram-negative-bacterium-type cell wall biogenesis
HQ396_06745	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
HQ396_06755	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
HQ396_06760	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
HQ396_06780	COG0242	peptide deformylase activity
HQ396_06810	COG0384	phenazine biosynthesis protein PhzF
HQ396_06820	COG2824	Alkylphosphonate utilization operon protein PhnA
HQ396_06845	COG0588	phosphoglycerate mutase activity
HQ396_06860	COG2840	Smr protein MutS2
HQ396_06865	COG2890	protein-(glutamine-N5) methyltransferase activity
HQ396_06870	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
HQ396_06880	COG0513	Belongs to the DEAD box helicase family
HQ396_06885	COG5654	RES domain protein
HQ396_06895	COG0814	amino acid
HQ396_06900	COG1609	Transcriptional regulator
HQ396_06905	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
HQ396_06905	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
HQ396_06910	COG1105	Belongs to the carbohydrate kinase PfkB family
HQ396_06915	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HQ396_06915	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
HQ396_06915	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HQ396_06920	COG2140	Oxalate decarboxylase
HQ396_06925	COG1609	Transcriptional regulator
HQ396_06940	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
HQ396_06940	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HQ396_06950	COG3716	PTS system mannose fructose sorbose family IID component
HQ396_06955	COG2942	2-epimerase
HQ396_06960	COG3313	Fe-S protein
HQ396_06965	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
HQ396_06970	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
HQ396_06975	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HQ396_06980	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HQ396_06990	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
HQ396_07015	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
HQ396_07020	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
HQ396_07025	COG0291	Belongs to the bacterial ribosomal protein bL35 family
HQ396_07035	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
HQ396_07045	COG0776	regulation of translation
HQ396_07085	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HQ396_07090	COG1879	ABC-type sugar transport system periplasmic component
HQ396_07095	COG1172	Belongs to the binding-protein-dependent transport system permease family
HQ396_07100	COG1129	ABC transporter
HQ396_07105	COG1869	D-ribose catabolic process
HQ396_07125	COG0037	tRNA processing
HQ396_07130	COG0589	response to stress
HQ396_07135	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
HQ396_07160	COG2010	Cytochrome c
HQ396_07175	COG3278	Belongs to the heme-copper respiratory oxidase family
HQ396_07185	COG1956	GAF domain-containing protein
HQ396_07190	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
HQ396_07200	COG0308	aminopeptidase N
HQ396_07215	COG0167	dihydroorotate dehydrogenase activity
HQ396_07225	COG0116	Belongs to the methyltransferase superfamily
HQ396_07225	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
HQ396_07235	COG0488	(ABC) transporter
HQ396_07255	COG1067	ATP-dependent peptidase activity
HQ396_07300	COG4128	Pfam Zonular occludens toxin
HQ396_07320	COG3141	response to X-ray
HQ396_07330	COG4221	oxidoreductase activity
HQ396_07380	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
HQ396_07400	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
HQ396_07400	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
HQ396_07420	COG0470	DNA polymerase III
HQ396_07425	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
HQ396_07435	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
HQ396_07445	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
HQ396_07450	COG1028	Short-chain dehydrogenase reductase Sdr
HQ396_07460	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HQ396_07465	COG0416	fatty acid biosynthetic process
HQ396_07470	COG0333	Belongs to the bacterial ribosomal protein bL32 family
HQ396_07475	COG1399	metal-binding, possibly nucleic acid-binding protein
HQ396_07490	COG2814	Major facilitator Superfamily
HQ396_07495	COG0424	maF-like protein
HQ396_07505	COG0564	pseudouridine synthase activity
HQ396_07510	COG1530	ribonuclease E activity
HQ396_07515	COG0306	phosphate transporter
HQ396_07520	COG0717	Belongs to the dCTP deaminase family
HQ396_07525	COG0572	uridine kinase
HQ396_07530	COG0489	protein tyrosine kinase activity
HQ396_07535	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HQ396_07535	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HQ396_07540	COG0625	glutathione transferase activity
HQ396_07545	COG1254	Belongs to the acylphosphatase family
HQ396_07550	COG0840	transmembrane signaling receptor activity
HQ396_07555	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
HQ396_07570	COG0709	Synthesizes selenophosphate from selenide and ATP
HQ396_07575	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
HQ396_07580	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
HQ396_07585	COG3437	response regulator, receiver
HQ396_07595	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
HQ396_07605	COG1643	Atp-dependent helicase
HQ396_07610	COG0517	IMP dehydrogenase activity
HQ396_07610	COG0617	tRNA 3'-terminal CCA addition
HQ396_07610	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
HQ396_07630	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
HQ396_07640	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
HQ396_07645	COG2832	Protein of unknown function (DUF454)
HQ396_07650	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HQ396_07665	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
HQ396_07675	COG0596	Alpha beta hydrolase
HQ396_07675	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
HQ396_07675	COG2226	methyltransferase
HQ396_07685	COG1214	PFAM Peptidase M22, glycoprotease
HQ396_07700	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
HQ396_07710	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
HQ396_07720	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
HQ396_07730	COG3437	response regulator, receiver
HQ396_07735	COG2199	diguanylate cyclase activity
HQ396_07740	COG0784	Response regulator, receiver
HQ396_07740	COG2198	Histidine kinase
HQ396_07740	COG2205	protein histidine kinase activity
HQ396_07745	COG0107	imidazoleglycerol-phosphate synthase activity
HQ396_07750	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
HQ396_07750	COG0140	phosphoribosyl-ATP diphosphatase activity
HQ396_07765	COG1288	antiporter activity
HQ396_07775	COG3134	Outer membrane lipoprotein
HQ396_07785	COG2080	2 iron, 2 sulfur cluster binding
HQ396_07790	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
HQ396_07795	COG1529	Aldehyde oxidase and xanthine dehydrogenase
HQ396_07800	COG2252	PERMEase
HQ396_07805	COG0402	S-adenosylhomocysteine deaminase activity
HQ396_07810	COG2233	PERMEase
HQ396_07820	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
HQ396_07825	COG0402	S-adenosylhomocysteine deaminase activity
HQ396_07830	COG0493	'glutamate synthase
HQ396_07830	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
HQ396_07840	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
HQ396_07845	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
HQ396_07845	COG3608	succinylglutamate desuccinylase aspartoacylase
HQ396_07850	COG0697	spore germination
HQ396_07855	COG0549	Belongs to the carbamate kinase family
HQ396_07865	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
HQ396_07870	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
HQ396_07875	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
HQ396_07880	COG3829	transcription factor binding
HQ396_07940	COG1024	Enoyl-CoA hydratase
HQ396_07940	COG1250	3-hydroxyacyl-CoA dehydrogenase
HQ396_07945	COG0183	Belongs to the thiolase family
HQ396_07950	COG0714	Associated with various cellular activities
HQ396_07980	COG1595	DNA-templated transcription, initiation
HQ396_07995	COG2067	long-chain fatty acid transport protein
HQ396_08000	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
HQ396_08020	COG3123	guanosine phosphorylase activity
HQ396_08030	COG1760	l-serine dehydratase
HQ396_08035	COG2951	lytic endotransglycosylase activity
HQ396_08040	COG3100	YcgL domain-containing protein
HQ396_08045	COG0850	regulation of cytokinetic process
HQ396_08050	COG2894	cell division
HQ396_08055	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
HQ396_08060	COG3099	Belongs to the UPF0263 family
HQ396_08065	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
HQ396_08105	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
HQ396_08115	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
HQ396_08120	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
HQ396_08140	COG0534	Mate efflux family protein
HQ396_08195	COG1560	Kdo2-lipid A biosynthetic process
HQ396_08200	COG1560	Kdo2-lipid A biosynthetic process
HQ396_08210	COG0583	DNA-binding transcription factor activity
HQ396_08215	COG0673	inositol 2-dehydrogenase activity
HQ396_08220	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
HQ396_08225	COG0583	DNA-binding transcription factor activity
HQ396_08230	COG1028	Short-chain dehydrogenase reductase Sdr
HQ396_08235	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
HQ396_08255	COG0583	DNA-binding transcription factor activity
HQ396_08260	COG3706	GGDEF domain
HQ396_08275	COG0667	Aldo Keto reductase
HQ396_08280	COG0583	DNA-binding transcription factor activity
HQ396_08290	COG0730	response to heat
HQ396_08310	COG1024	Enoyl-CoA hydratase
HQ396_08320	COG1960	acyl-CoA dehydrogenase activity
HQ396_08370	COG1584	GPR1 FUN34 yaaH family protein
HQ396_08375	COG3228	Belongs to the MtfA family
HQ396_08385	COG1115	amino acid carrier protein
HQ396_08435	COG3162	membrane
HQ396_08440	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HQ396_08445	COG0488	(ABC) transporter
HQ396_08450	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
HQ396_08455	COG0776	regulation of translation
HQ396_08460	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
HQ396_08470	COG0740	serine-type endopeptidase activity
HQ396_08475	COG0544	peptidyl-prolyl cis-trans isomerase activity
HQ396_08485	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
HQ396_08490	COG4591	ABC-type transport system involved in lipoprotein release permease component
HQ396_08495	COG1136	(ABC) transporter
HQ396_08500	COG4591	ABC-type transport system involved in lipoprotein release permease component
HQ396_08515	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
HQ396_08525	COG0697	spore germination
HQ396_08535	COG2062	phosphohistidine phosphatase, SixA
HQ396_08575	COG0518	GMP synthase (glutamine-hydrolyzing) activity
HQ396_08575	COG0519	Catalyzes the synthesis of GMP from XMP
HQ396_08580	COG0516	GMP reductase activity
HQ396_08580	COG0517	IMP dehydrogenase activity
HQ396_08585	COG3158	transport of potassium into the cell
HQ396_08605	COG0697	spore germination
HQ396_08610	COG1570	exodeoxyribonuclease VII activity
HQ396_08625	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
HQ396_08630	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
HQ396_08635	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
HQ396_08680	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HQ396_08685	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HQ396_08690	COG1120	ATPase activity
HQ396_08700	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
HQ396_08705	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HQ396_08715	COG1028	Short-chain dehydrogenase reductase Sdr
HQ396_08725	COG3433	isochorismatase activity
HQ396_08725	COG1535	isochorismatase
HQ396_08750	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
HQ396_08755	COG3300	MHYT domain
HQ396_08755	COG5001	Diguanylate cyclase
HQ396_08780	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
HQ396_08785	COG0563	adenylate kinase activity
HQ396_08790	COG0326	Molecular chaperone. Has ATPase activity
HQ396_08795	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
HQ396_08820	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
HQ396_08825	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
HQ396_08830	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
HQ396_08840	COG3158	transport of potassium into the cell
HQ396_08845	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
HQ396_08850	COG0651	ATP synthesis coupled electron transport
HQ396_08855	COG0650	Formate hydrogenlyase subunit 4
HQ396_08860	COG3261	NADH dehydrogenase
HQ396_08860	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
HQ396_08865	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
HQ396_08870	COG3260	NADH ubiquinone oxidoreductase 20
HQ396_08880	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
HQ396_08890	COG1921	L-seryl-tRNASec selenium transferase activity
HQ396_08900	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
HQ396_08905	COG0298	carbon dioxide binding
HQ396_08915	COG0309	Hydrogenase expression formation protein (HypE)
HQ396_08920	COG0375	protein maturation
HQ396_08925	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
HQ396_08930	COG3842	ATPase activity
HQ396_08935	COG0444	Belongs to the ABC transporter superfamily
HQ396_08940	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
HQ396_08960	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
HQ396_08970	COG5557	Pfam Polysulphide reductase, NrfD
HQ396_08975	COG0437	4 iron, 4 sulfur cluster binding
HQ396_08980	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
HQ396_08995	COG2198	Histidine kinase
HQ396_08995	COG0643	Histidine kinase
HQ396_09000	COG3290	protein histidine kinase activity
HQ396_09000	COG0840	transmembrane signaling receptor activity
HQ396_09005	COG0835	chemotaxis
HQ396_09015	COG2201	protein-glutamate methylesterase activity
HQ396_09025	COG0840	transmembrane signaling receptor activity
HQ396_09125	COG0582	viral genome integration into host DNA
HQ396_09195	COG0672	)-iron permease
HQ396_09215	COG2814	Major facilitator Superfamily
HQ396_09225	COG1136	(ABC) transporter
HQ396_09230	COG0577	efflux transmembrane transporter activity
HQ396_09265	COG1139	Iron-sulfur cluster binding protein
HQ396_09275	COG1620	l-lactate permease
HQ396_09280	COG0583	DNA-binding transcription factor activity
HQ396_09290	COG0346	lactoylglutathione lyase activity
HQ396_09295	COG0596	Alpha beta hydrolase
HQ396_09315	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HQ396_09320	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
HQ396_09320	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
HQ396_09325	COG0527	aspartate kinase activity
HQ396_09340	COG1619	proteins homologs of microcin C7 resistance protein MccF
HQ396_09345	COG4667	esterase of the alpha-beta hydrolase superfamily
HQ396_09365	COG1648	precorrin-2 dehydrogenase activity
HQ396_09365	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
HQ396_09375	COG0393	Putative heavy-metal-binding
HQ396_09395	COG1252	NADH dehydrogenase
HQ396_09400	COG3150	esterase
HQ396_09405	COG2233	PERMEase
HQ396_09420	COG2354	Protein conserved in bacteria
HQ396_09430	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
HQ396_09435	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
HQ396_09470	COG0537	adenosine 5'-monophosphoramidase activity
HQ396_09500	COG1301	dicarboxylic acid transport
HQ396_09510	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HQ396_09515	COG0861	Integral membrane protein TerC family
HQ396_09530	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
HQ396_09535	COG0601	transmembrane transport
HQ396_09545	COG2095	MarC family integral membrane protein
HQ396_09565	COG3275	phosphorelay sensor kinase activity
HQ396_09570	COG3279	Response regulator of the LytR AlgR family
HQ396_09575	COG1966	Carbon starvation protein
HQ396_09585	COG1566	PFAM secretion protein HlyD family protein
HQ396_09590	COG1061	Type III restriction enzyme res subunit
HQ396_09595	COG2027	D-alanyl-D-alanine carboxypeptidase
HQ396_09600	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
HQ396_09610	COG0436	Aminotransferase
HQ396_09615	COG1288	antiporter activity
HQ396_09620	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
HQ396_09635	COG0697	spore germination
HQ396_09640	COG4657	Part of a membrane complex involved in electron transport
HQ396_09645	COG2878	Part of a membrane complex involved in electron transport
HQ396_09660	COG4659	FMN binding
HQ396_09665	COG4660	Part of a membrane complex involved in electron transport
HQ396_09670	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
HQ396_09675	COG0346	lactoylglutathione lyase activity
HQ396_09690	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
HQ396_09705	COG2050	protein possibly involved in aromatic compounds catabolism
HQ396_09725	COG1253	flavin adenine dinucleotide binding
HQ396_09735	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
HQ396_09770	COG0625	glutathione transferase activity
HQ396_09775	COG0625	glutathione transferase activity
HQ396_09785	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
HQ396_09800	COG0564	pseudouridine synthase activity
HQ396_09805	COG2203	Gaf domain
HQ396_09805	COG2199	diguanylate cyclase activity
HQ396_09810	COG0840	transmembrane signaling receptor activity
HQ396_09820	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
HQ396_09820	COG0392	lysyltransferase activity
HQ396_09830	COG2194	sulfuric ester hydrolase activity
HQ396_10015	COG4790	Type iii secretion
HQ396_10020	COG4794	Type iii secretion
HQ396_10030	COG4792	protein secretion
HQ396_10045	COG0670	Belongs to the BI1 family
HQ396_10050	COG1289	transmembrane transporter activity
HQ396_10055	COG2920	part of a sulfur-relay system
HQ396_10060	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
HQ396_10065	COG0285	dihydrofolate synthase activity
HQ396_10070	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
HQ396_10075	COG0101	tRNA pseudouridine synthase activity
HQ396_10085	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
HQ396_10090	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
HQ396_10095	COG0671	phosphoesterase, PA-phosphatase related
HQ396_10115	COG3038	cytochrome b561
HQ396_10150	COG0574	Belongs to the PEP-utilizing enzyme family
HQ396_10150	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HQ396_10155	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
HQ396_10185	COG2304	oxidoreductase activity
HQ396_10240	COG1242	4 iron, 4 sulfur cluster binding
HQ396_10245	COG0070	glutamate synthase
HQ396_10245	COG0069	glutamate synthase activity
HQ396_10245	COG0067	glutamate synthase
HQ396_10250	COG0493	'glutamate synthase
HQ396_10260	COG0765	amino acid transport
HQ396_10265	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HQ396_10280	COG0789	Transcriptional regulator
HQ396_10295	COG4104	PAAR repeat-containing protein
HQ396_10305	COG0513	Belongs to the DEAD box helicase family
HQ396_10310	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HQ396_10345	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
HQ396_10350	COG0505	Belongs to the CarA family
HQ396_10355	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
HQ396_10365	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
HQ396_10370	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
HQ396_10375	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
HQ396_10380	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
HQ396_10385	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
HQ396_10405	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HQ396_10405	COG2205	protein histidine kinase activity
HQ396_10420	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
HQ396_10445	COG0023	Translation Initiation Factor
HQ396_10450	COG2119	membrane
HQ396_10480	COG2203	Gaf domain
HQ396_10480	COG2199	diguanylate cyclase activity
HQ396_10510	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
HQ396_10520	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
HQ396_10530	COG0437	4 iron, 4 sulfur cluster binding
HQ396_10535	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
HQ396_10580	COG2801	Transposase and inactivated derivatives
HQ396_10605	COG0322	excinuclease ABC activity
HQ396_10610	COG2197	response regulator
HQ396_10615	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
HQ396_10620	COG2835	tetraacyldisaccharide 4'-kinase activity
HQ396_10625	COG1663	tetraacyldisaccharide 4'-kinase activity
HQ396_10630	COG1132	(ABC) transporter
HQ396_10635	COG0658	competence protein
HQ396_10635	COG2333	competence protein COMEC
HQ396_10650	COG0433	COG0433 Predicted ATPase
HQ396_10655	COG1448	Aminotransferase
HQ396_10670	COG1199	ATP-dependent helicase activity
HQ396_10680	COG0123	including yeast histone deacetylase and acetoin utilization protein
HQ396_10685	COG0477	Major facilitator Superfamily
HQ396_10715	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
HQ396_10730	COG2271	Major facilitator Superfamily
HQ396_10740	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HQ396_10750	COG1126	abc transporter atp-binding protein
HQ396_10785	COG1253	flavin adenine dinucleotide binding
HQ396_10790	COG0704	Plays a role in the regulation of phosphate uptake
HQ396_10795	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
HQ396_10800	COG0581	inorganic phosphate transmembrane transporter activity
HQ396_10805	COG0573	inorganic phosphate transmembrane transporter activity
HQ396_10810	COG0590	tRNA wobble adenosine to inosine editing
HQ396_10825	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
HQ396_10845	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
HQ396_10850	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
HQ396_10855	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
HQ396_10860	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
HQ396_10885	COG2716	regulation of RNA biosynthetic process
HQ396_10890	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
HQ396_10900	COG2239	Acts as a magnesium transporter
HQ396_10920	COG1706	bacterial-type flagellum-dependent cell motility
HQ396_10925	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
HQ396_10935	COG4787	bacterial-type flagellum-dependent cell motility
HQ396_10945	COG1749	Flagellar hook protein flgE
HQ396_10960	COG1815	bacterial-type flagellum-dependent cell motility
HQ396_10970	COG0784	Response regulator, receiver
HQ396_10970	COG0835	chemotaxis
HQ396_10975	COG1261	Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly
HQ396_10990	COG0622	Phosphoesterase
HQ396_11020	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
HQ396_11025	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HQ396_11030	COG1882	Formate acetyltransferase
HQ396_11035	COG1349	DNA-binding transcription factor activity
HQ396_11070	COG1278	Cold shock
HQ396_11150	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
HQ396_11165	COG2755	lipolytic protein G-D-S-L family
HQ396_11165	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
HQ396_11230	COG2165	general secretion pathway protein
HQ396_11240	COG1459	type II secretion system
HQ396_11245	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
HQ396_11250	COG2801	Transposase and inactivated derivatives
HQ396_11265	COG1091	dTDP-4-dehydrorhamnose reductase activity
HQ396_11280	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HQ396_11285	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HQ396_11290	COG1309	transcriptional regulator
HQ396_11305	COG1946	Acyl-CoA thioesterase
HQ396_11315	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
HQ396_11325	COG0009	L-threonylcarbamoyladenylate synthase
HQ396_11335	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
HQ396_11340	COG0512	Glutamine amidotransferase of anthranilate synthase
HQ396_11340	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
HQ396_11345	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
HQ396_11350	COG0134	indole-3-glycerol-phosphate synthase activity
HQ396_11350	COG0135	phosphoribosylanthranilate isomerase activity
HQ396_11355	COG0133	tryptophan synthase activity
HQ396_11360	COG0159	tryptophan synthase activity
HQ396_11385	COG1988	membrane-bound metal-dependent
HQ396_11415	COG4521	taurine ABC transporter
HQ396_11430	COG2175	clavaminate synthase activity
HQ396_11445	COG0109	protoheme IX farnesyltransferase activity
HQ396_11450	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
HQ396_11455	COG1845	cytochrome c oxidase, subunit III
HQ396_11460	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
HQ396_11465	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
HQ396_11510	COG2211	Major facilitator Superfamily
HQ396_11525	COG0708	Exodeoxyribonuclease III
HQ396_11570	COG0095	Lipoate-protein ligase
HQ396_11600	COG0640	Transcriptional regulator
HQ396_11615	COG1285	pathogenesis
HQ396_11645	COG0484	heat shock protein binding
HQ396_11650	COG0443	Heat shock 70 kDa protein
HQ396_11655	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
HQ396_11660	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
HQ396_11680	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HQ396_11685	COG0577	efflux transmembrane transporter activity
HQ396_11685	COG1136	(ABC) transporter
HQ396_11700	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
HQ396_11740	COG1396	sequence-specific DNA binding
HQ396_11740	COG1917	Cupin 2, conserved barrel domain protein
HQ396_11755	COG0531	amino acid
HQ396_11765	COG0531	amino acid
HQ396_11775	COG1283	sodium-dependent phosphate transmembrane transporter activity
HQ396_11785	COG3384	dioxygenase
HQ396_11790	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HQ396_11790	COG2205	protein histidine kinase activity
HQ396_11805	COG0813	purine-nucleoside phosphorylase activity
HQ396_11815	COG1943	Transposase
HQ396_11835	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
HQ396_11840	COG0083	homoserine kinase activity
HQ396_11850	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
HQ396_11855	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
HQ396_11870	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
HQ396_11880	COG0745	RESPONSE REGULATOR receiver
HQ396_11895	COG4988	ABC transporter
HQ396_11935	COG0542	response to heat
HQ396_11940	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
HQ396_11945	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
HQ396_11955	COG2190	(PTS) system
HQ396_11970	COG3038	cytochrome b561
HQ396_11985	COG0419	ATPase involved in DNA repair
HQ396_11990	COG0420	3'-5' exonuclease activity
HQ396_12000	COG2974	May be involved in recombination
HQ396_12010	COG4651	solute:proton antiporter activity
HQ396_12010	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
HQ396_12025	COG0469	pyruvate kinase activity
HQ396_12040	COG2706	6-phosphogluconolactonase activity
HQ396_12050	COG0281	malic enzyme
HQ396_12065	COG0437	4 iron, 4 sulfur cluster binding
HQ396_12115	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
HQ396_12125	COG3852	Histidine kinase
HQ396_12130	COG2204	response regulator
HQ396_12140	COG4662	Binding-protein-dependent transport system inner membrane component
HQ396_12150	COG0746	molybdenum cofactor guanylyltransferase activity
HQ396_12160	COG1289	transmembrane transporter activity
HQ396_12165	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
HQ396_12195	COG3220	belongs to the UPF0276 family
HQ396_12230	COG4166	transmembrane transport
HQ396_12235	COG0601	transmembrane transport
HQ396_12240	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
HQ396_12245	COG0444	Belongs to the ABC transporter superfamily
HQ396_12260	COG2971	BadF BadG BcrA BcrD
HQ396_12270	COG0840	transmembrane signaling receptor activity
HQ396_12290	COG3724	N-succinylarginine dihydrolase activity
HQ396_12295	COG0616	signal peptide processing
HQ396_12300	COG1028	Short-chain dehydrogenase reductase Sdr
HQ396_12305	COG0583	DNA-binding transcription factor activity
HQ396_12315	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
HQ396_12325	COG0583	DNA-binding transcription factor activity
HQ396_12330	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
HQ396_12380	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
HQ396_12390	COG3091	SprT-like family
HQ396_12400	COG1385	rRNA (uridine-N3-)-methyltransferase activity
HQ396_12405	COG0189	ligase activity
HQ396_12415	COG1678	Uncharacterized ACR, COG1678
HQ396_12420	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
HQ396_12425	COG3104	oligopeptide transport
HQ396_12435	COG0714	Associated with various cellular activities
HQ396_12450	COG1115	amino acid carrier protein
HQ396_12455	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
HQ396_12470	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
HQ396_12480	COG1301	dicarboxylic acid transport
HQ396_12485	COG2877	3-deoxy-8-phosphooctulonate synthase activity
HQ396_12490	COG2912	Transglutaminase-like superfamily
HQ396_12500	COG2890	protein-(glutamine-N5) methyltransferase activity
HQ396_12505	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
HQ396_12510	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
HQ396_12515	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
HQ396_12520	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
HQ396_12530	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HQ396_12535	COG0737	Belongs to the 5'-nucleotidase family
HQ396_12540	COG0193	aminoacyl-tRNA hydrolase activity
HQ396_12545	COG0012	GTP binding
HQ396_12590	COG0471	metal ion transport
HQ396_12590	COG0490	domain, Protein
HQ396_12610	COG3097	Belongs to the UPF0267 family
HQ396_12620	COG2214	Heat shock protein DnaJ domain protein
HQ396_12625	COG0443	Heat shock 70 kDa protein
HQ396_12635	COG0366	Alpha amylase catalytic
HQ396_12645	COG1013	pyruvate-flavodoxin oxidoreductase activity
HQ396_12645	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
HQ396_12645	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
HQ396_12645	COG0674	pyruvate-flavodoxin oxidoreductase activity
HQ396_12655	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
HQ396_12665	COG1012	belongs to the aldehyde dehydrogenase family
HQ396_12675	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
HQ396_12690	COG0180	Tryptophanyl-tRNA synthetase
HQ396_12700	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
HQ396_12710	COG0338	D12 class N6 adenine-specific DNA methyltransferase
HQ396_12725	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
HQ396_12755	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
HQ396_12760	COG0583	DNA-binding transcription factor activity
HQ396_12795	COG0739	heme binding
HQ396_12810	COG0584	glycerophosphoryl diester phosphodiesterase
HQ396_12820	COG1053	succinate dehydrogenase
HQ396_12825	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
HQ396_12830	COG3029	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
HQ396_12855	COG3214	Protein conserved in bacteria
HQ396_12895	COG0642	Histidine kinase
HQ396_12915	COG0516	GMP reductase activity
HQ396_12935	COG3647	Membrane
HQ396_12945	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HQ396_12955	COG3706	GGDEF domain
HQ396_12965	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
HQ396_12980	COG3706	GGDEF domain
HQ396_12990	COG1335	isochorismatase
HQ396_12995	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
HQ396_13000	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
HQ396_13005	COG1702	phosphate starvation-inducible protein PhoH
HQ396_13010	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
HQ396_13015	COG4535	Mg2 and Co2 transporter CorC
HQ396_13020	COG0815	Transfers the fatty acyl group on membrane lipoproteins
HQ396_13025	COG2888	peptidyl-tyrosine sulfation
HQ396_13045	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
HQ396_13050	COG0799	negative regulation of ribosome biogenesis
HQ396_13055	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
HQ396_13060	COG0768	penicillin binding
HQ396_13065	COG0772	Belongs to the SEDS family
HQ396_13070	COG2951	lytic endotransglycosylase activity
HQ396_13085	COG2921	Belongs to the UPF0250 family
HQ396_13095	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
HQ396_13105	COG3545	Serine hydrolase
HQ396_13110	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
HQ396_13125	COG0789	Transcriptional regulator
HQ396_13135	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
HQ396_13140	COG1970	mechanosensitive ion channel activity
HQ396_13145	COG4974	Belongs to the 'phage' integrase family
HQ396_13155	COG0312	modulator of DNA gyrase
HQ396_13160	COG0312	modulator of DNA gyrase
HQ396_13230	COG3279	Response regulator of the LytR AlgR family
HQ396_13235	COG1966	Carbon starvation protein
HQ396_13260	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
HQ396_13270	COG2211	Major facilitator Superfamily
HQ396_13275	COG1185	polyribonucleotide nucleotidyltransferase activity
HQ396_13280	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
HQ396_13285	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
HQ396_13290	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
HQ396_13295	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
HQ396_13300	COG0195	Participates in both transcription termination and antitermination
HQ396_13305	COG0779	Required for maturation of 30S ribosomal subunits
HQ396_13320	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
HQ396_13325	COG0149	triose-phosphate isomerase activity
HQ396_13330	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
HQ396_13345	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
HQ396_13350	COG1534	Rna-binding protein
HQ396_13365	COG1360	Flagellar Motor Protein
HQ396_13370	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
HQ396_13375	COG1722	exodeoxyribonuclease VII activity
HQ396_13385	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
HQ396_13395	COG0601	transmembrane transport
HQ396_13410	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
HQ396_13415	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
HQ396_13420	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
HQ396_13425	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
HQ396_13445	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
HQ396_13445	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
HQ396_13450	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
HQ396_13460	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
HQ396_13475	COG3381	protein complex oligomerization
HQ396_13495	COG3300	MHYT domain
HQ396_13495	COG5001	Diguanylate cyclase
HQ396_13505	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
HQ396_13510	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
HQ396_13515	COG0511	ligase activity, forming carbon-carbon bonds
HQ396_13520	COG0439	Biotin carboxylase
HQ396_13545	COG0583	DNA-binding transcription factor activity
HQ396_13550	COG0604	alcohol dehydrogenase
HQ396_13555	COG2264	protein methyltransferase activity
HQ396_13570	COG0778	Nitroreductase
HQ396_13575	COG0446	pyridine nucleotide-disulphide oxidoreductase
HQ396_13575	COG1902	pentaerythritol trinitrate reductase activity
HQ396_13580	COG0616	signal peptide processing
HQ396_13600	COG3139	Protein of unknown function (DUF1315)
HQ396_13605	COG0252	asparaginase activity
HQ396_13610	COG0786	glutamate:sodium symporter activity
HQ396_13625	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
HQ396_13635	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
HQ396_13640	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
HQ396_13645	COG0175	sulfate reduction
HQ396_13650	COG2113	Glycine betaine
HQ396_13655	COG4176	ABC-type proline glycine betaine transport system permease component
HQ396_13670	COG3610	response to peptide
HQ396_13675	COG2966	Psort location CytoplasmicMembrane, score
HQ396_13685	COG0521	Mo-molybdopterin cofactor biosynthetic process
HQ396_13700	COG1028	Short-chain dehydrogenase reductase Sdr
HQ396_13710	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
HQ396_13760	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
HQ396_13765	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
HQ396_13800	COG1858	cytochrome C peroxidase
HQ396_13815	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HQ396_13840	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
HQ396_13855	COG1073	alpha beta
HQ396_13860	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
HQ396_13865	COG2195	Cleaves the N-terminal amino acid of tripeptides
HQ396_13875	COG0444	Belongs to the ABC transporter superfamily
HQ396_13890	COG4174	ABC transporter (Permease)
HQ396_13905	COG0811	peptide transport
HQ396_13910	COG0811	peptide transport
HQ396_13915	COG0848	biopolymer transport protein
HQ396_13965	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
HQ396_13970	COG0840	transmembrane signaling receptor activity
HQ396_13980	COG1278	Cold shock
HQ396_14020	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
HQ396_14025	COG1162	GTPase activity
HQ396_14030	COG0688	phosphatidylethanolamine metabolic process
HQ396_14035	COG4628	conserved protein (DUF2132)
HQ396_14050	COG3059	membrane
HQ396_14055	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
HQ396_14060	COG2207	Transcriptional regulator
HQ396_14070	COG3300	MHYT domain
HQ396_14070	COG5001	Diguanylate cyclase
HQ396_14075	COG3076	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome
HQ396_14115	COG2897	thiosulfate sulfurtransferase activity
HQ396_14120	COG2066	Belongs to the glutaminase family
HQ396_14125	COG3171	Protein conserved in bacteria
HQ396_14130	COG0220	tRNA (guanine-N7-)-methyltransferase activity
HQ396_14135	COG2234	aminopeptidase activity
HQ396_14135	COG4935	Belongs to the peptidase S8 family
HQ396_14140	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HQ396_14145	COG2200	EAL domain
HQ396_14150	COG1090	epimerase
HQ396_14160	COG4181	ATPase activity
HQ396_14165	COG2755	lipolytic protein G-D-S-L family
HQ396_14190	COG2985	domain, Protein
HQ396_14190	COG0569	domain protein
HQ396_14205	COG2917	probably involved in intracellular septation
HQ396_14210	COG2350	Protein conserved in bacteria
HQ396_14220	COG1555	photosystem II stabilization
HQ396_14225	COG1210	Utp--glucose-1-phosphate uridylyltransferase
HQ396_14230	COG3104	oligopeptide transport
HQ396_14235	COG0745	RESPONSE REGULATOR receiver
HQ396_14280	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
HQ396_14285	COG1280	lysine exporter protein (LysE YggA)
HQ396_14310	COG0316	Belongs to the HesB IscA family
HQ396_14320	COG0038	chloride channel
HQ396_14325	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
HQ396_14340	COG0671	phosphoesterase, PA-phosphatase related
HQ396_14350	COG3437	response regulator, receiver
HQ396_14350	COG0784	Response regulator, receiver
HQ396_14360	COG2076	Multidrug Resistance protein
HQ396_14370	COG0346	lactoylglutathione lyase activity
HQ396_14375	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
HQ396_14380	COG1643	Atp-dependent helicase
HQ396_14395	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
HQ396_14400	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
HQ396_14415	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
HQ396_14420	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
HQ396_14445	COG1775	2-hydroxyglutaryl-CoA dehydratase, D-component
HQ396_14450	COG0842	Transport permease protein
HQ396_14455	COG1131	(ABC) transporter
HQ396_14480	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
HQ396_14495	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
HQ396_14510	COG1136	(ABC) transporter
HQ396_14530	COG0840	transmembrane signaling receptor activity
HQ396_14565	COG0529	Catalyzes the synthesis of activated sulfate
HQ396_14570	COG0471	metal ion transport
HQ396_14570	COG3273	potassium ion transport
HQ396_14575	COG2895	sulfate adenylyltransferase (ATP) activity
HQ396_14580	COG0175	sulfate reduction
HQ396_14585	COG1648	precorrin-2 dehydrogenase activity
HQ396_14585	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
HQ396_14590	COG0330	HflC and HflK could
HQ396_14595	COG1585	Membrane protein implicated in regulation of membrane protease activity
HQ396_14600	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
HQ396_14600	COG0517	IMP dehydrogenase activity
HQ396_14605	COG0488	(ABC) transporter
HQ396_14615	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
HQ396_14620	COG0583	DNA-binding transcription factor activity
HQ396_14655	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HQ396_14665	COG0668	transmembrane transport
HQ396_14675	COG2731	YhcH YjgK YiaL family protein
HQ396_14690	COG1794	racemase activity, acting on amino acids and derivatives
HQ396_14705	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HQ396_14755	COG0561	phosphatase activity
HQ396_14790	COG1846	Transcriptional regulator
HQ396_14795	COG1764	response to oxidative stress
HQ396_14800	COG2130	NADP-dependent
HQ396_14805	COG1051	belongs to the nudix hydrolase family
HQ396_14825	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
HQ396_14830	COG1640	4-alpha-glucanotransferase
HQ396_14835	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
HQ396_14840	COG0676	glucose-6-phosphate 1-epimerase activity
HQ396_14845	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
HQ396_14925	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
HQ396_14930	COG2885	chlorophyll binding
HQ396_14935	COG0823	Involved in the tonB-independent uptake of proteins
HQ396_14950	COG0811	peptide transport
HQ396_14955	COG0824	Thioesterase
HQ396_14960	COG3790	cyd operon protein YbgE
HQ396_14965	COG4890	Cyd operon protein YbgT
HQ396_14970	COG1294	oxidase, subunit
HQ396_14975	COG1271	oxidase subunit
HQ396_14980	COG2255	four-way junction helicase activity
HQ396_14985	COG0632	four-way junction helicase activity
HQ396_14990	COG0840	transmembrane signaling receptor activity
HQ396_14995	COG0442	prolyl-tRNA aminoacylation
HQ396_15000	COG4221	oxidoreductase activity
HQ396_15015	COG1024	Enoyl-CoA hydratase
HQ396_15035	COG4166	transmembrane transport
HQ396_15050	COG1872	DUF167
HQ396_15055	COG0762	integral membrane protein
HQ396_15060	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HQ396_15065	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
HQ396_15080	COG3022	response to hydroperoxide
HQ396_15085	COG0513	Belongs to the DEAD box helicase family
HQ396_15090	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
HQ396_15115	COG0735	belongs to the Fur family
HQ396_15120	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HQ396_15135	COG0776	regulation of translation
HQ396_15145	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
HQ396_15170	COG0560	Phosphoserine phosphatase
HQ396_15180	COG3447	MASE1 domain protein
HQ396_15180	COG5001	Diguanylate cyclase
HQ396_15180	COG5002	protein histidine kinase activity
HQ396_15185	COG0813	purine-nucleoside phosphorylase activity
HQ396_15190	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
HQ396_15195	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
HQ396_15200	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
HQ396_15210	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
HQ396_15220	COG2165	general secretion pathway protein
HQ396_15230	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HQ396_15235	COG0004	ammonium transporteR
HQ396_15300	COG0582	viral genome integration into host DNA
HQ396_15315	COG0795	lipopolysaccharide-transporting ATPase activity
HQ396_15320	COG0795	lipopolysaccharide-transporting ATPase activity
HQ396_15325	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
HQ396_15330	COG2927	DNA polymerase III (CHI subunit)
HQ396_15335	COG0525	valine-tRNA ligase activity
HQ396_15345	COG0586	Pfam SNARE associated Golgi protein
HQ396_15350	COG1686	Belongs to the peptidase S11 family
HQ396_15385	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
HQ396_15390	COG0527	aspartate kinase activity
HQ396_15395	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
HQ396_15405	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
HQ396_15415	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
HQ396_15435	COG3068	Protein conserved in bacteria
HQ396_15445	COG0739	heme binding
HQ396_15465	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
HQ396_15470	COG1121	(ABC) transporter
HQ396_15475	COG1108	ABC-type Mn2 Zn2 transport systems permease components
HQ396_15480	COG0583	DNA-binding transcription factor activity
HQ396_15485	COG0697	spore germination
HQ396_15490	COG1573	uracil-dna glycosylase
HQ396_15495	COG2962	Rard protein
HQ396_15505	COG2827	Endonuclease containing a URI domain
HQ396_15520	COG1842	Phage shock protein A
HQ396_15525	COG0204	Acyl-transferase
HQ396_15545	COG3118	belongs to the thioredoxin family
HQ396_15605	COG1566	PFAM secretion protein HlyD family protein
HQ396_15620	COG1051	belongs to the nudix hydrolase family
HQ396_15625	COG3150	esterase
HQ396_15635	COG3151	Protein conserved in bacteria
HQ396_15640	COG0494	nUDIX hydrolase
HQ396_15645	COG1538	Outer membrane efflux protein
HQ396_15650	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
HQ396_15650	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
HQ396_15655	COG1560	Kdo2-lipid A biosynthetic process
HQ396_15670	COG1392	Phosphate transport regulator
HQ396_15675	COG0306	phosphate transporter
HQ396_15680	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
HQ396_15705	COG0583	DNA-binding transcription factor activity
HQ396_15710	COG1380	Effector of murein hydrolase LrgA
HQ396_15730	COG0617	tRNA 3'-terminal CCA addition
HQ396_15735	COG3267	Type II secretory pathway component ExeA
HQ396_15735	COG3409	Peptidoglycan-binding domain 1 protein
HQ396_15745	COG1194	a g-specific adenine glycosylase
HQ396_15750	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
HQ396_15760	COG3111	PFAM Bacterial OB fold (BOF) protein
HQ396_15765	COG3240	lipase activity
HQ396_15780	COG3009	Protein conserved in bacteria
HQ396_15790	COG2995	paraquat-inducible protein a
HQ396_15800	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
HQ396_15810	COG5001	Diguanylate cyclase
HQ396_15810	COG3706	GGDEF domain
HQ396_15810	COG4251	negative regulation of phosphorylation
HQ396_15810	COG2203	Gaf domain
HQ396_15815	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HQ396_15820	COG2813	Specifically methylates the guanine in position
HQ396_15825	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
HQ396_15830	COG0297	glycogen (starch) synthase activity
HQ396_15870	COG1757	Na H antiporter
HQ396_15875	COG0583	DNA-binding transcription factor activity
HQ396_15880	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
HQ396_15885	COG3842	ATPase activity
HQ396_15890	COG1176	ABC-type spermidine putrescine transport system, permease component I
HQ396_15895	COG1177	transmembrane transport
HQ396_15900	COG1012	belongs to the aldehyde dehydrogenase family
HQ396_15910	COG5006	permease, DMT superfamily
HQ396_15915	COG1522	sequence-specific DNA binding
HQ396_15920	COG0110	maltose O-acetyltransferase activity
HQ396_15925	COG0366	Alpha amylase catalytic
HQ396_15930	COG1263	PTS System
HQ396_15930	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HQ396_15950	COG0252	asparaginase activity
HQ396_15965	COG1803	Methylglyoxal synthase
HQ396_15990	COG1444	tRNA N-acetyltransferase activity
HQ396_15995	COG1028	Short-chain dehydrogenase reductase Sdr
HQ396_16000	COG0784	Response regulator, receiver
HQ396_16000	COG0835	chemotaxis
HQ396_16045	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
HQ396_16050	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
HQ396_16065	COG0477	Major facilitator Superfamily
HQ396_16070	COG0523	cobalamin synthesis protein
HQ396_16080	COG1280	lysine exporter protein (LysE YggA)
HQ396_16090	COG2200	EAL domain
HQ396_16095	COG1049	propionate catabolic process, 2-methylcitrate cycle
HQ396_16100	COG1752	Esterase of the alpha-beta hydrolase superfamily
HQ396_16105	COG0840	transmembrane signaling receptor activity
HQ396_16110	COG0840	transmembrane signaling receptor activity
HQ396_16120	COG5002	protein histidine kinase activity
HQ396_16120	COG5001	Diguanylate cyclase
HQ396_16120	COG3447	MASE1 domain protein
HQ396_16125	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
HQ396_16130	COG0508	dehydrogenase complex catalyzes the overall conversion of
HQ396_16135	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
HQ396_16140	COG2186	Transcriptional regulator
HQ396_16165	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
HQ396_16170	COG1459	type II secretion system
HQ396_16185	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
HQ396_16190	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
HQ396_16195	COG0494	nUDIX hydrolase
HQ396_16205	COG0653	protein targeting
HQ396_16215	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
HQ396_16220	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
HQ396_16225	COG0849	cell division
HQ396_16235	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
HQ396_16245	COG0772	Belongs to the SEDS family
HQ396_16250	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
HQ396_16255	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
HQ396_16260	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
HQ396_16270	COG0768	penicillin binding
HQ396_16275	COG3116	cell division
HQ396_16280	COG0275	rRNA processing
HQ396_16285	COG2001	Belongs to the MraZ family
HQ396_16305	COG1360	Flagellar Motor Protein
HQ396_16310	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
HQ396_16315	COG1191	sigma factor activity
HQ396_16340	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
HQ396_16350	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
HQ396_16365	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
HQ396_16380	COG1706	bacterial-type flagellum-dependent cell motility
HQ396_16385	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
HQ396_16390	COG4786	Flagellar basal body rod
HQ396_16400	COG1749	Flagellar hook protein flgE
HQ396_16415	COG1815	bacterial-type flagellum-dependent cell motility
HQ396_16450	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
HQ396_16460	COG1677	Flagellar hook-basal body complex protein FliE
HQ396_16510	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
HQ396_16515	COG3107	peptidoglycan biosynthetic process
HQ396_16520	COG0792	nuclease activity
HQ396_16525	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
HQ396_16530	COG2823	Periplasmic or secreted lipoprotein
HQ396_16535	COG2969	positive regulation of protein catabolic process
HQ396_16540	COG0625	glutathione transferase activity
HQ396_16545	COG2857	Cytochrome c1
HQ396_16550	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
HQ396_16555	COG0723	plastoquinol--plastocyanin reductase activity
HQ396_16560	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
HQ396_16565	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
HQ396_16570	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
HQ396_16580	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HQ396_16585	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HQ396_16615	COG3964	amidohydrolase
HQ396_16630	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
HQ396_16630	COG3711	transcriptional antiterminator
HQ396_16635	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
HQ396_16640	COG1660	Displays ATPase and GTPase activities
HQ396_16645	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
HQ396_16655	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
HQ396_16660	COG1137	ATPase activity
HQ396_16665	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
HQ396_16670	COG3117	lipopolysaccharide transmembrane transporter activity
HQ396_16675	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
HQ396_16680	COG0517	IMP dehydrogenase activity
HQ396_16680	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
HQ396_16685	COG1127	ABC transporter
HQ396_16690	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
HQ396_16695	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
HQ396_16700	COG2854	intermembrane phospholipid transfer
HQ396_16710	COG5007	Belongs to the BolA IbaG family
HQ396_16715	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HQ396_16720	COG0312	modulator of DNA gyrase
HQ396_16725	COG3028	Belongs to the UPF0307 family
HQ396_16735	COG2926	Belongs to the UPF0265 family
HQ396_16775	COG3135	benzoate transporter
HQ396_16805	COG3047	cAMP biosynthetic process
HQ396_16820	COG2197	response regulator
HQ396_16830	COG0629	single-stranded DNA binding
HQ396_16850	COG1278	Cold shock
HQ396_16855	COG4771	TonB-dependent receptor
HQ396_16860	COG3706	GGDEF domain
HQ396_16860	COG4251	negative regulation of phosphorylation
HQ396_16860	COG2203	Gaf domain
HQ396_16860	COG5001	Diguanylate cyclase
HQ396_16905	COG0346	lactoylglutathione lyase activity
HQ396_16930	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
HQ396_16935	COG2259	Doxx family
HQ396_16940	COG1741	Belongs to the pirin family
HQ396_16950	COG0583	DNA-binding transcription factor activity
HQ396_16975	COG1176	ABC-type spermidine putrescine transport system, permease component I
HQ396_16985	COG3842	ATPase activity
HQ396_17015	COG1247	-acetyltransferase
HQ396_17020	COG0753	catalase activity
HQ396_17045	COG0494	nUDIX hydrolase
HQ396_17060	COG2957	Belongs to the agmatine deiminase family
HQ396_17065	COG0583	DNA-binding transcription factor activity
HQ396_17070	COG3284	Transcriptional regulator
HQ396_17085	COG1461	Dihydroxyacetone kinase
HQ396_17090	COG2376	Dihydroxyacetone kinase
HQ396_17095	COG2252	PERMEase
HQ396_17130	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
HQ396_17135	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
HQ396_17140	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
HQ396_17145	COG0049	tRNA binding
HQ396_17150	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
HQ396_17155	COG2168	tRNA wobble position uridine thiolation
HQ396_17160	COG2923	Belongs to the DsrF TusC family
HQ396_17165	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
HQ396_17170	COG0251	oxidation-reduction process
HQ396_17175	COG2964	Protein conserved in bacteria
HQ396_17180	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HQ396_17185	COG0085	RNA polymerase activity
HQ396_17190	COG0222	ribosome binding
HQ396_17195	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
HQ396_17200	COG0081	regulation of translation
HQ396_17205	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
HQ396_17210	COG0250	Participates in transcription elongation, termination and antitermination
HQ396_17225	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
HQ396_17250	COG0812	UDP-N-acetylmuramate dehydrogenase activity
HQ396_17260	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
HQ396_17280	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HQ396_17285	COG3005	denitrification pathway
HQ396_17320	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
HQ396_17345	COG2205	protein histidine kinase activity
HQ396_17370	COG5413	integral membrane protein
HQ396_17380	COG1522	sequence-specific DNA binding
HQ396_17385	COG2502	aspartate--ammonia ligase
HQ396_17390	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
HQ396_17395	COG0542	response to heat
HQ396_17410	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
HQ396_17415	COG0446	pyridine nucleotide-disulphide oxidoreductase
HQ396_17425	COG3681	Belongs to the UPF0597 family
HQ396_17435	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
HQ396_17440	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
HQ396_17445	COG1979	alcohol dehydrogenase
HQ396_17450	COG2207	Transcriptional regulator
HQ396_17455	COG3040	lipid binding
HQ396_17470	COG0688	phosphatidylethanolamine metabolic process
HQ396_17485	COG0540	Belongs to the ATCase OTCase family
HQ396_17490	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
HQ396_17495	COG1438	arginine binding
HQ396_17500	COG1288	antiporter activity
HQ396_17505	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
HQ396_17535	COG0840	transmembrane signaling receptor activity
HQ396_17575	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
HQ396_17580	COG2017	converts alpha-aldose to the beta-anomer
HQ396_17585	COG0667	Aldo Keto reductase
HQ396_17590	COG1968	undecaprenyl-diphosphatase activity
HQ396_17595	COG3806	Anti-sigma factor
HQ396_17600	COG1595	DNA-templated transcription, initiation
HQ396_17625	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
HQ396_17630	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
HQ396_17645	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
HQ396_17655	COG2116	formate transmembrane transporter activity
HQ396_17660	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
HQ396_17660	COG1648	precorrin-2 dehydrogenase activity
HQ396_17665	COG2239	Acts as a magnesium transporter
HQ396_17675	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
HQ396_17680	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
HQ396_17690	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
HQ396_17700	COG0514	ATP-dependent DNA helicase (RecQ)
HQ396_17705	COG2050	protein possibly involved in aromatic compounds catabolism
HQ396_17720	COG2258	MOSC domain
HQ396_17725	COG1177	transmembrane transport
HQ396_17730	COG1176	ABC-type spermidine putrescine transport system, permease component I
HQ396_17735	COG3842	ATPase activity
HQ396_17775	COG3045	CreA protein
HQ396_17780	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HQ396_17785	COG0443	Heat shock 70 kDa protein
HQ396_17800	COG0366	Alpha amylase catalytic
HQ396_17815	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HQ396_17820	COG0745	RESPONSE REGULATOR receiver
HQ396_17825	COG2205	protein histidine kinase activity
HQ396_17835	COG0281	malic enzyme
HQ396_17845	COG0254	rRNA binding
HQ396_17850	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
HQ396_17870	COG0129	dihydroxy-acid dehydratase activity
HQ396_17880	COG3978	acetolactate synthase activity
HQ396_17890	COG0606	chelatase, subunit chli
HQ396_17895	COG0204	Acyl-transferase
HQ396_17900	COG0204	Acyl-transferase
HQ396_17905	COG1683	Conserved Protein
HQ396_17915	COG1335	isochorismatase
HQ396_17925	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
HQ396_17930	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
HQ396_17935	COG3639	organic phosphonate transmembrane transporter activity
HQ396_17940	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
HQ396_17945	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
HQ396_17955	COG3084	Protein conserved in bacteria
HQ396_17960	COG2203	Gaf domain
HQ396_17960	COG5001	Diguanylate cyclase
HQ396_17960	COG4251	negative regulation of phosphorylation
HQ396_17960	COG3706	GGDEF domain
HQ396_17965	COG0789	Transcriptional regulator
HQ396_17975	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
HQ396_17980	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
HQ396_17985	COG1561	YicC-like family, N-terminal region
HQ396_18005	COG3306	glycosyltransferase involved in LPS biosynthesis
HQ396_18020	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
HQ396_18030	COG0156	8-amino-7-oxononanoate synthase activity
HQ396_18035	COG1063	alcohol dehydrogenase
HQ396_18040	COG3245	cytochrome
HQ396_18050	COG0210	DNA helicase
HQ396_18055	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
HQ396_18060	COG2166	iron-sulfur cluster assembly
HQ396_18065	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
HQ396_18105	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
HQ396_18115	COG0583	DNA-binding transcription factor activity
HQ396_18140	COG2223	nitrite transmembrane transporter activity
HQ396_18160	COG2223	nitrite transmembrane transporter activity
HQ396_18170	COG1528	Iron-storage protein
HQ396_18185	COG0589	response to stress
HQ396_18225	COG3642	lipopolysaccharide core region biosynthetic process
HQ396_18230	COG0859	PFAM glycosyl transferase family 9
HQ396_18240	COG1758	RNA polymerase activity
HQ396_18245	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HQ396_18295	COG0469	pyruvate kinase activity
HQ396_18345	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
HQ396_18370	COG0745	RESPONSE REGULATOR receiver
HQ396_18375	COG2814	Major facilitator Superfamily
HQ396_18390	COG3977	Valine--pyruvate aminotransferase
HQ396_18395	COG0071	Belongs to the small heat shock protein (HSP20) family
HQ396_18400	COG0071	Belongs to the small heat shock protein (HSP20) family
HQ396_18405	COG2378	regulation of single-species biofilm formation
HQ396_18425	COG0592	DNA-directed DNA polymerase activity
HQ396_18430	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
HQ396_18445	COG1126	abc transporter atp-binding protein
HQ396_18450	COG0230	Belongs to the bacterial ribosomal protein bL34 family
HQ396_18455	COG0594	ribonuclease P activity
HQ396_18460	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
HQ396_18465	COG0706	membrane insertase activity
HQ396_18470	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
HQ396_18485	COG1120	ATPase activity
HQ396_18490	COG4615	Cyclic peptide transporter
HQ396_18500	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
HQ396_18505	COG0445	tRNA wobble uridine modification
HQ396_18510	COG0357	Ribosomal RNA small subunit methyltransferase G
HQ396_18515	COG1192	Involved in chromosome partitioning
HQ396_18520	COG1475	DNA binding
HQ396_18530	COG0356	it plays a direct role in the translocation of protons across the membrane
HQ396_18540	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
HQ396_18545	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HQ396_18550	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
HQ396_18555	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
HQ396_18560	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
HQ396_18565	COG0355	proton-transporting ATP synthase activity, rotational mechanism
HQ396_18570	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
HQ396_18575	COG4452	Inner membrane protein CreD
HQ396_18585	COG2205	protein histidine kinase activity
HQ396_18590	COG0745	RESPONSE REGULATOR receiver
HQ396_18595	COG1349	DNA-binding transcription factor activity
HQ396_18600	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
HQ396_18605	COG2771	luxR family
HQ396_18615	COG0811	peptide transport
HQ396_18620	COG0811	peptide transport
HQ396_18625	COG0848	biopolymer transport protein
HQ396_18630	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
HQ396_18670	COG0402	S-adenosylhomocysteine deaminase activity
HQ396_18675	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HQ396_18685	COG3165	ubiquinone biosynthetic process from chorismate
HQ396_18700	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
HQ396_18705	COG0805	protein transport
HQ396_18710	COG0084	hydrolase, TatD family'
HQ396_18730	COG0742	ribosomal rna small subunit methyltransferase
HQ396_18745	COG0248	Ppx GppA phosphatase
HQ396_18750	COG0513	Belongs to the DEAD box helicase family
HQ396_18755	COG3118	belongs to the thioredoxin family
HQ396_18770	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
HQ396_18795	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HQ396_18835	COG1609	Transcriptional regulator
HQ396_18840	COG3604	Transcriptional regulator
HQ396_18845	COG0426	domain, Protein
HQ396_18845	COG1773	rubredoxin
HQ396_18860	COG0348	domain, Protein
HQ396_18865	COG0814	amino acid
HQ396_18900	COG2046	Belongs to the sulfate adenylyltransferase family
HQ396_18900	COG0529	Catalyzes the synthesis of activated sulfate
HQ396_18910	COG0751	glycine-tRNA ligase activity
HQ396_18915	COG0752	glycyl-tRNA synthetase alpha subunit
HQ396_18920	COG2818	Glycosylase
HQ396_18925	COG0840	transmembrane signaling receptor activity
HQ396_18930	COG2885	chlorophyll binding
HQ396_18935	COG0251	oxidation-reduction process
HQ396_18940	COG0425	Belongs to the sulfur carrier protein TusA family
HQ396_18965	COG0183	Belongs to the thiolase family
HQ396_18970	COG1250	3-hydroxyacyl-CoA dehydrogenase
HQ396_18970	COG1024	Enoyl-CoA hydratase
HQ396_18975	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
HQ396_18980	COG0006	proline dipeptidase activity
HQ396_18985	COG1739	Uncharacterized protein family UPF0029
HQ396_18995	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
HQ396_19035	COG0583	DNA-binding transcription factor activity
HQ396_19040	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
HQ396_19045	COG0166	Belongs to the GPI family
HQ396_19055	COG0668	transmembrane transport
HQ396_19060	COG1309	transcriptional regulator
HQ396_19065	COG0756	dUTP diphosphatase activity
HQ396_19075	COG2003	Belongs to the UPF0758 family
HQ396_19080	COG0227	Belongs to the bacterial ribosomal protein bL28 family
HQ396_19085	COG0267	Belongs to the bacterial ribosomal protein bL33 family
HQ396_19095	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
HQ396_19100	COG2990	Protein conserved in bacteria
HQ396_19105	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
HQ396_19110	COG0859	PFAM glycosyl transferase family 9
HQ396_19115	COG0463	Glycosyl transferase, family 2
HQ396_19120	COG0859	PFAM glycosyl transferase family 9
HQ396_19125	COG1519	Transferase
HQ396_19145	COG1609	Transcriptional regulator
HQ396_19150	COG0604	alcohol dehydrogenase
HQ396_19165	COG1580	Controls the rotational direction of flagella during chemotaxis
HQ396_19170	COG3161	chorismate lyase activity
HQ396_19180	COG2937	Belongs to the GPAT DAPAT family
HQ396_19185	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
HQ396_19200	COG0534	Mate efflux family protein
HQ396_19205	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
HQ396_19210	COG2205	protein histidine kinase activity
HQ396_19215	COG0745	RESPONSE REGULATOR receiver
HQ396_19225	COG1045	serine acetyltransferase
HQ396_19235	COG3074	FtsZ-dependent cytokinesis
HQ396_19240	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
HQ396_19245	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HQ396_19245	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HQ396_19250	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
HQ396_19285	COG1609	Transcriptional regulator
HQ396_19290	COG3250	beta-galactosidase activity
HQ396_19295	COG2731	YhcH YjgK YiaL family protein
HQ396_19300	COG0531	amino acid
HQ396_19305	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HQ396_19310	COG0531	amino acid
HQ396_19315	COG0385	Bile acid
HQ396_19340	COG0583	DNA-binding transcription factor activity
HQ396_19350	COG4603	Belongs to the binding-protein-dependent transport system permease family
HQ396_19355	COG3845	ABC transporter
HQ396_19360	COG1744	ABC transporter substrate-binding protein PnrA-like
HQ396_19365	COG0210	DNA helicase
HQ396_19380	COG0583	DNA-binding transcription factor activity
HQ396_19440	COG2391	methyltransferase activity
HQ396_19450	COG1280	lysine exporter protein (LysE YggA)
HQ396_19460	COG2962	Rard protein
HQ396_19470	COG1012	belongs to the aldehyde dehydrogenase family
HQ396_19475	COG1396	sequence-specific DNA binding
HQ396_19490	COG0518	GMP synthase (glutamine-hydrolyzing) activity
HQ396_19490	COG0519	Catalyzes the synthesis of GMP from XMP
HQ396_19495	COG0686	Belongs to the AlaDH PNT family
HQ396_19520	COG1322	Protein conserved in bacteria
HQ396_19525	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
HQ396_19530	COG0569	domain protein
HQ396_19545	COG0242	peptide deformylase activity
HQ396_19555	COG0758	DNA mediated transformation
HQ396_19560	COG2922	Belongs to the Smg family
HQ396_19565	COG0551	DNA topoisomerase type I activity
HQ396_19575	COG0009	L-threonylcarbamoyladenylate synthase
HQ396_19580	COG0408	coproporphyrinogen oxidase activity
HQ396_19585	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
HQ396_19595	COG0218	Necessary for normal cell division and for the maintenance of normal septation
HQ396_19605	COG3078	GTPase activator activity
HQ396_19615	COG0635	Involved in the biosynthesis of porphyrin-containing compound
HQ396_19620	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
HQ396_19625	COG2204	response regulator
HQ396_19630	COG3852	Histidine kinase
HQ396_19640	COG0174	glutamine synthetase
HQ396_19645	COG1217	gtp-binding protein TYPA
HQ396_19650	COG1295	ribonuclease BN
HQ396_19655	COG1295	ribonuclease BN
HQ396_19660	COG1490	D-aminoacyl-tRNA deacylase activity
HQ396_19670	COG0456	acetyltransferase
HQ396_19680	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
HQ396_19685	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HQ396_19690	COG2610	gluconate transmembrane transporter activity
HQ396_19695	COG3265	gluconokinase activity
HQ396_19705	COG0800	Aldolase
HQ396_19710	COG1609	Transcriptional regulator
HQ396_19720	COG4942	peptidase
HQ396_19725	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
HQ396_19730	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HQ396_19735	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
HQ396_19740	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
HQ396_19745	COG0316	Belongs to the HesB IscA family
HQ396_19745	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
HQ396_19755	COG0596	Alpha beta hydrolase
HQ396_19775	COG2183	response to ionizing radiation
HQ396_19780	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
HQ396_19800	COG0051	transcription antitermination factor activity, RNA binding
HQ396_19805	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
HQ396_19810	COG0088	Forms part of the polypeptide exit tunnel
HQ396_19815	COG0089	rRNA binding
HQ396_19820	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
HQ396_19825	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
HQ396_19830	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
HQ396_19835	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
HQ396_19840	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
HQ396_19845	COG0255	Belongs to the universal ribosomal protein uL29 family
HQ396_19850	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
HQ396_19855	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
HQ396_19860	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
HQ396_19865	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
HQ396_19870	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
HQ396_19875	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
HQ396_19880	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
HQ396_19885	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
HQ396_19890	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
HQ396_19895	COG1841	ribosomal large subunit assembly
HQ396_19900	COG0200	Binds to the 23S rRNA
HQ396_19905	COG0201	protein transport
HQ396_19910	COG0257	Belongs to the bacterial ribosomal protein bL36 family
HQ396_19915	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
HQ396_19920	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
HQ396_19925	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
HQ396_19930	COG0202	RNA polymerase activity
HQ396_19935	COG0203	ribosomal protein L17
HQ396_19985	COG2249	NAD(P)H dehydrogenase (quinone) activity
HQ396_19990	COG0583	DNA-binding transcription factor activity
HQ396_19995	COG4221	oxidoreductase activity
HQ396_20010	COG1770	oligopeptidase
HQ396_20030	COG3714	YhhN family
HQ396_20055	COG1301	dicarboxylic acid transport
HQ396_20075	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
HQ396_20085	COG0741	lytic transglycosylase activity
HQ396_20125	COG0552	protein localization to endoplasmic reticulum
HQ396_20135	COG2177	Part of the ABC transporter FtsEX involved in
HQ396_20145	COG0288	reversible hydration of carbon dioxide
HQ396_20155	COG1228	amidohydrolase
HQ396_20160	COG0010	Belongs to the arginase family
HQ396_20170	COG2986	histidine ammonia-lyase
HQ396_20180	COG2200	EAL domain
HQ396_20185	COG2200	EAL domain
HQ396_20185	COG2199	diguanylate cyclase activity
HQ396_20230	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
HQ396_20235	COG1459	type II secretion system
HQ396_20245	COG2165	general secretion pathway protein
HQ396_20255	COG4968	Prepilin-type N-terminal cleavage methylation domain
HQ396_20280	COG1077	Cell shape determining protein MreB Mrl
HQ396_20285	COG1792	Involved in formation and maintenance of cell shape
HQ396_20290	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
HQ396_20295	COG0424	maF-like protein
HQ396_20300	COG1530	ribonuclease E activity
HQ396_20305	COG3164	Protein of unknown function
HQ396_20315	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
HQ396_20320	COG0312	modulator of DNA gyrase
HQ396_20335	COG0477	Major facilitator Superfamily
HQ396_20345	COG3437	response regulator, receiver
HQ396_20350	COG5002	protein histidine kinase activity
HQ396_20350	COG0784	Response regulator, receiver
HQ396_20350	COG2205	protein histidine kinase activity
HQ396_20355	COG2172	sigma factor antagonist activity
HQ396_20360	COG1366	Belongs to the anti-sigma-factor antagonist family
HQ396_20380	COG3700	Belongs to the class B bacterial acid phosphatase family
HQ396_20385	COG2321	neutral zinc metallopeptidase
HQ396_20395	COG1639	'signal transduction protein
HQ396_20420	COG0189	ligase activity
HQ396_20430	COG0642	Histidine kinase
HQ396_20435	COG0745	RESPONSE REGULATOR receiver
HQ396_20455	COG3766	membrane
HQ396_20465	COG0754	glutathionylspermidine amidase activity
HQ396_20470	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
HQ396_20475	COG0352	thiamine-phosphate diphosphorylase activity
HQ396_20480	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
HQ396_20490	COG2022	thiamine diphosphate biosynthetic process
HQ396_20495	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
HQ396_20520	COG3417	Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1B (PBP1b)
HQ396_20540	COG3706	GGDEF domain
HQ396_20545	COG0814	amino acid
HQ396_20550	COG3932	Exopolysaccharide synthesis, ExoD
HQ396_20570	COG1733	regulation of RNA biosynthetic process
HQ396_20610	COG1494	fructose-1,6-bisphosphatase
HQ396_20625	COG2959	enzyme of heme biosynthesis
HQ396_20635	COG0181	hydroxymethylbilane synthase activity
HQ396_20640	COG3072	Adenylate cyclase
HQ396_20650	COG1965	Belongs to the frataxin family
HQ396_20660	COG0019	diaminopimelate decarboxylase activity
HQ396_20680	COG1011	Hydrolase
HQ396_20700	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
HQ396_20705	COG0561	phosphatase activity
HQ396_20720	COG0842	Transport permease protein
HQ396_20720	COG1129	ABC transporter
HQ396_20730	COG1546	Belongs to the CinA family
HQ396_20730	COG1058	Belongs to the CinA family
HQ396_20735	COG1418	mRNA catabolic process
HQ396_20740	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
HQ396_20750	COG1522	sequence-specific DNA binding
HQ396_20755	COG1368	sulfuric ester hydrolase activity
HQ396_20795	COG4221	oxidoreductase activity
HQ396_20815	COG1979	alcohol dehydrogenase
HQ396_20825	COG2873	o-acetylhomoserine
HQ396_20850	COG5380	lipid catabolic process
HQ396_20855	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
HQ396_20870	COG2949	membrane
HQ396_20875	COG3291	Pkd domain containing protein
HQ396_20885	COG3539	Fimbrial protein
HQ396_20895	COG3188	usher protein
HQ396_20900	COG3121	Chaperone
HQ396_20905	COG3539	Fimbrial protein
HQ396_20920	COG0318	PFAM AMP-dependent synthetase and ligase
HQ396_20925	COG1441	menaquinone biosynthetic process
HQ396_20930	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
HQ396_20935	COG0596	Alpha beta hydrolase
HQ396_20940	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
HQ396_20945	COG1169	isochorismate synthase
HQ396_20950	COG1575	Belongs to the MenA family. Type 1 subfamily
HQ396_20975	COG0513	Belongs to the DEAD box helicase family
HQ396_20980	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
HQ396_20985	COG1988	membrane-bound metal-dependent
HQ396_21025	COG3263	regulation of cellular component size
HQ396_21030	COG3722	fumarate hydratase activity
HQ396_21035	COG0246	Mannitol dehydrogenase
HQ396_21040	COG2213	PTS system mannitol-specific
HQ396_21040	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
HQ396_21050	COG1309	transcriptional regulator
HQ396_21055	COG4776	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction
HQ396_21065	COG3916	Acyl-homoserine-lactone synthase
HQ396_21070	COG2771	luxR family
HQ396_21085	COG3133	Outer membrane lipoprotein
HQ396_21090	COG0456	acetyltransferase
HQ396_21110	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
HQ396_21115	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
HQ396_21125	COG3031	protein transport across the cell outer membrane
HQ396_21135	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
HQ396_21140	COG1459	type II secretion system
HQ396_21145	COG2165	general secretion pathway protein
HQ396_21160	COG2165	general secretion pathway protein
HQ396_21165	COG4795	General secretion pathway protein
HQ396_21170	COG3156	type II secretion system protein K
HQ396_21180	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
HQ396_21195	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
HQ396_21200	COG1011	Hydrolase
HQ396_21205	COG0494	nUDIX hydrolase
HQ396_21210	COG1218	3'(2'),5'-bisphosphate nucleotidase
HQ396_21215	COG0814	amino acid
HQ396_21220	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HQ396_21225	COG3708	Transcriptional regulator
HQ396_21225	COG2207	Transcriptional regulator
HQ396_21240	COG0527	aspartate kinase activity
HQ396_21240	COG0460	homoserine dehydrogenase
HQ396_21250	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
HQ396_21260	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
HQ396_21265	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
HQ396_21275	COG0137	argininosuccinate synthase activity
HQ396_21280	COG0165	Argininosuccinate lyase
HQ396_21315	COG3174	membrane
HQ396_21330	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
HQ396_21340	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
HQ396_21345	COG0583	DNA-binding transcription factor activity
HQ396_21350	COG3397	chitin binding
HQ396_21355	COG0840	transmembrane signaling receptor activity
HQ396_21405	COG1328	CTP reductase activity
HQ396_21410	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HQ396_21425	COG1448	Aminotransferase
HQ396_21465	COG0513	Belongs to the DEAD box helicase family
HQ396_21485	COG0840	transmembrane signaling receptor activity
HQ396_21500	COG3112	Uncharacterised protein family (UPF0231)
HQ396_21510	COG2610	gluconate transmembrane transporter activity
HQ396_21515	COG1929	Belongs to the glycerate kinase type-1 family
HQ396_21530	COG0583	DNA-binding transcription factor activity
HQ396_21535	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
HQ396_21550	COG0347	Belongs to the P(II) protein family
HQ396_21555	COG1840	ABC-type Fe3 transport system, periplasmic component
HQ396_21565	COG3842	ATPase activity
HQ396_21570	COG2837	iron assimilation
HQ396_21575	COG1438	arginine binding
HQ396_21580	COG1126	abc transporter atp-binding protein
HQ396_21585	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HQ396_21590	COG4215	(ABC) transporter
HQ396_21595	COG4160	amino acid transport
HQ396_21600	COG0039	L-malate dehydrogenase activity
HQ396_21605	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
HQ396_21610	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
HQ396_21610	COG1017	nitric oxide dioxygenase activity
HQ396_21620	COG4536	flavin adenine dinucleotide binding
HQ396_21625	COG4137	Cytochrome C assembly protein
HQ396_21630	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
HQ396_21635	COG0228	four-way junction DNA binding
HQ396_21640	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
HQ396_21645	COG0336	Belongs to the RNA methyltransferase TrmD family
HQ396_21650	COG0335	large ribosomal subunit rRNA binding
HQ396_21660	COG3066	DNA modification
HQ396_21665	COG1051	belongs to the nudix hydrolase family
HQ396_21675	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
HQ396_21685	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
HQ396_21695	COG0583	DNA-binding transcription factor activity
HQ396_21700	COG0640	Transcriptional regulator
HQ396_21705	COG0268	Binds directly to 16S ribosomal RNA
HQ396_21720	COG0196	riboflavin kinase activity
HQ396_21730	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
HQ396_21735	COG1047	Peptidyl-prolyl cis-trans
HQ396_21740	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
HQ396_21745	COG4970	Tfp pilus assembly protein FimT
HQ396_21800	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
HQ396_21800	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
HQ396_21815	COG1854	S-ribosylhomocysteine lyase activity
HQ396_21820	COG3706	GGDEF domain
HQ396_21825	COG0557	exoribonuclease II activity
HQ396_21830	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HQ396_21840	COG2153	protein acetylation
HQ396_21860	COG1914	H( )-stimulated, divalent metal cation uptake system
HQ396_21865	COG0360	Binds together with S18 to 16S ribosomal RNA
HQ396_21870	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
HQ396_21875	COG0359	binds to the 23S rRNA
HQ396_21905	COG1238	metal cluster binding
HQ396_21910	COG0612	Peptidase, M16
HQ396_21915	COG2918	glutathione biosynthetic process
HQ396_21925	COG1022	Amp-dependent synthetase and ligase
HQ396_21935	COG0456	acetyltransferase
HQ396_21945	COG0714	Associated with various cellular activities
HQ396_21955	COG3300	MHYT domain
HQ396_21955	COG5001	Diguanylate cyclase
HQ396_21965	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
HQ396_21990	COG1902	pentaerythritol trinitrate reductase activity
HQ396_22000	COG2852	Protein conserved in bacteria
HQ396_22010	COG2957	Belongs to the agmatine deiminase family
HQ396_22045	COG0513	Belongs to the DEAD box helicase family
HQ396_22070	COG1912	Pfam S-adenosyl-l-methionine hydroxide adenosyltransferase