locus-tag	class	description
AH4AK4_0001	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
AH4AK4_0002	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
AH4AK4_0003	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
AH4AK4_0004	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
AH4AK4_0006	ENOG4105D29	Helix-turn-helix type 11 domain protein
AH4AK4_0007	ENOG4105ECQ	AraC Family Transcriptional Regulator
AH4AK4_0009	ENOG4105IGJ	Zn-dependent Hydrolase of the beta-lactamase fold protein
AH4AK4_0010	ENOG4108ZNX	Heat shock protein
AH4AK4_0011	ENOG4108ZNX	Heat shock protein
AH4AK4_0012	ENOG4105JKW	Valine--pyruvate aminotransferase
AH4AK4_0016	ENOG4105C2C	drug resistance transporter, Bcr CflA
AH4AK4_0017	ENOG4105EEX	Two component transcriptional regulator (Winged helix family
AH4AK4_0018	ENOG4105C08	Histidine kinase
AH4AK4_0021	ENOG4105C8X	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity)
AH4AK4_0022	ENOG4105D9K	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity)
AH4AK4_0023	ENOG4105DC8	reductase
AH4AK4_0024	ENOG4105BZU	Histidine kinase
AH4AK4_0025	ENOG4105BZS	acriflavin resistance protein
AH4AK4_0026	ENOG410624X	efflux transporter, rnd family, mfp subunit
AH4AK4_0027	ENOG4105Y7M	Transcriptional regulator, TetR family
AH4AK4_0033	ENOG4105DQF	Hydrolase
AH4AK4_0034	ENOG4108EUD	Lysophospholipase
AH4AK4_0036	ENOG4105FE8	tRNA (Guanosine-2'-O-)-methyltransferase
AH4AK4_0037	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
AH4AK4_0038	ENOG4105VFG	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity)
AH4AK4_0039	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
AH4AK4_0040	ENOG4105DKP	glycosyl transferase, family 9
AH4AK4_0041	ENOG4108W7E	Catalyzes the ATP-dependent phosphorylation of the 3- deoxy-D-manno-octulosonic acid (Kdo) residue in Kdo-lipid IV(A) at the 4-OH position (By similarity)
AH4AK4_0043	ENOG4105EMK	carboxylate amino acid amine transporter
AH4AK4_0049	ENOG4108M6U	Universal stress protein A
AH4AK4_0050	ENOG4105RKW	reductase (By
AH4AK4_0051	ENOG4105BZU	Histidine kinase
AH4AK4_0052	ENOG41090A1	ferritin
AH4AK4_0053	ENOG4105CBX	hi0933 family
AH4AK4_0054	ENOG4105EU0	Major facilitator Superfamily
AH4AK4_0058	ENOG4108N3D	putative enzyme
AH4AK4_0059	ENOG4108NN8	Fimbrial protein
AH4AK4_0060	ENOG4108GWT	fimbrillin MatB
AH4AK4_0061	ENOG4107ZHV	Transcriptional regulator
AH4AK4_0062	ENOG4105BZU	Histidine kinase
AH4AK4_0064	ENOG4108HRK	Histidine kinase
AH4AK4_0065	ENOG4105DY9	regulatoR
AH4AK4_0066	ENOG4105FCD	Major Facilitator
AH4AK4_0067	ENOG4105CY8	phosphoribosylaminoimidazole carboxylase atpase subunit
AH4AK4_0068	ENOG4108UM6	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity)
AH4AK4_0069	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
AH4AK4_0070	ENOG4105F03	Provides the (R)-glutamate required for cell wall biosynthesis (By similarity)
AH4AK4_0077	ENOG4105CUZ	uba thif-type nad fad binding protein
AH4AK4_0078	ENOG4105P9C	Participates in cysteine desulfuration mediated by SufS. Cysteine desulfuration mobilizes sulfur from L-cysteine to yield L-alanine and constitutes an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules. Functions as a sulfur acceptor for SufS, by mediating the direct transfer of the sulfur atom from the S-sulfanylcysteine of SufS, an intermediate product of cysteine desulfuration process (By similarity)
AH4AK4_0079	ENOG4105C9B	Cysteine desulfurase
AH4AK4_0081	ENOG4105C4R	Atp-dependent dna helicase
AH4AK4_0082	ENOG4105BZU	Histidine kinase
AH4AK4_0085	ENOG4105CPQ	Dehydrogenase
AH4AK4_0086	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
AH4AK4_0087	ENOG41062JF	Transcriptional regulator
AH4AK4_0088	ENOG4105CUI	Catalyzes the interconversion between ADP-D-glycero- beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose (By similarity)
AH4AK4_0098	ENOG4105DIQ	Transcriptional regulator
AH4AK4_0099	ENOG4105D3Z	quinone oxidoreductase, yhdh yhfp family
AH4AK4_0103	ENOG4105X6C	Flagellar basal body-associated protein FliL
AH4AK4_0104	ENOG4105VEI	Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4- hydroxybenzoate (4HB) for the ubiquinone pathway (By similarity)
AH4AK4_0105	ENOG4105C4G	Synthesis of 3-octaprenyl-4-hydroxybenzoate (By similarity)
AH4AK4_0106	ENOG4105E55	glycerol-3-phosphate acyltransferase
AH4AK4_0107	ENOG4105DS7	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity)
AH4AK4_0110	ENOG4107R73	Mate efflux family protein
AH4AK4_0111	ENOG4108UIQ	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity)
AH4AK4_0112	ENOG4105E0F	Histidine kinase
AH4AK4_0113	ENOG4105E3W	Two component transcriptional regulator (Winged helix family
AH4AK4_0114	ENOG41076HS	cation diffusion facilitator family transporter
AH4AK4_0115	ENOG4105D7W	serine acetyltransferase
AH4AK4_0117	ENOG41065UX	Non-essential, abundant cell division factor that is required for proper Z-ring formation. It is recruited early to the divisome by direct interaction with FtsZ, stimulating Z-ring assembly and thereby promoting cell division earlier in the cell cycle. Its recruitment to the Z-ring requires functional FtsA or ZipA (By similarity)
AH4AK4_0118	ENOG4108556	Isoprenoid biosynthesis protein with amidotransferase-like domain
AH4AK4_0119	ENOG4105C2M	dna polymerase I
AH4AK4_0120	ENOG4108Z0R	Transferase
AH4AK4_0128	ENOG4105CQ4	Transcriptional regulator
AH4AK4_0129	ENOG4105CNT	hydrolase family 2
AH4AK4_0130	ENOG4105FK9	beta-D-galactosidase beta subunit
AH4AK4_0131	ENOG4105E5D	amino acid
AH4AK4_0132	ENOG4108Y51	tRNA-binding protein
AH4AK4_0133	ENOG4105E5D	amino acid
AH4AK4_0134	ENOG4105DHU	Bile acid
AH4AK4_0138	ENOG4105C4W	S-formylglutathione hydrolase
AH4AK4_0140	ENOG4105CC0	LysR family Transcriptional regulator
AH4AK4_0143	ENOG4105UIB	(ABC) transporter
AH4AK4_0144	ENOG4108JQ9	ABC transporter
AH4AK4_0145	ENOG4105DIH	basic membrane
AH4AK4_0147	ENOG4105C4R	Atp-dependent dna helicase
AH4AK4_0149	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
AH4AK4_0150	ENOG4108UK5	Transposase
AH4AK4_0151	ENOG4108UK5	Transposase
AH4AK4_0152	ENOG4105HEI	LysR family (Transcriptional regulator
AH4AK4_0154	ENOG4105KVH	Transcriptional regulator
AH4AK4_0157	ENOG4105CHR	reductase
AH4AK4_0160	ENOG4105K3G	Periplasmic Protein
AH4AK4_0163	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
AH4AK4_0166	ENOG41061EV	selenium-binding protein YdfZ
AH4AK4_0169	ENOG4108YH8	Covalently attaches a chromophore to Cys residue(s) of phycobiliproteins (By similarity)
AH4AK4_0170	ENOG4105EJC	lysr family transcriptional regulator
AH4AK4_0171	ENOG410829K	Lysine exporter protein (Lyse ygga)
AH4AK4_0172	ENOG4105CUC	YeeE YedE family protein
AH4AK4_0175	ENOG4105ECQ	AraC Family Transcriptional Regulator
AH4AK4_0176	ENOG4105FR1	rard protein
AH4AK4_0179	ENOG4105C26	Dehydrogenase
AH4AK4_0180	ENOG4108JCI	Transcriptional regulator
AH4AK4_0182	ENOG4105C26	Dehydrogenase
AH4AK4_0183	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
AH4AK4_0184	ENOG4107R11	Transcriptional regulator
AH4AK4_0185	ENOG4108TFM	Kinase, PfkB family
AH4AK4_0189	ENOG4105CGY	Dna recombination protein
AH4AK4_0190	ENOG4105D37	Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA (By similarity)
AH4AK4_0191	ENOG4105C1A	potassium transporter peripheral membrane
AH4AK4_0192	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
AH4AK4_0193	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
AH4AK4_0194	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
AH4AK4_0196	ENOG4105C79	DNA protecting protein DprA
AH4AK4_0197	ENOG4108RPN	Protein smg homolog
AH4AK4_0198	ENOG4108WI1	Dna topoisomerase
AH4AK4_0199	ENOG4105EK0	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
AH4AK4_0200	ENOG4105DBS	Key enzyme in heme biosynthesis. Catalyzes the oxidative decarboxylation of propionic acid side chains of rings A and B of coproporphyrinogen III (By similarity)
AH4AK4_0201	ENOG4105E2X	shikimate dehydrogenase
AH4AK4_0202	ENOG4105WHM	Necessary for normal cell division and for the maintenance of normal septation (By similarity)
AH4AK4_0203	ENOG4106RE7	Cytochrome
AH4AK4_0204	ENOG4105ZR3	A GTPase-activating protein (GAP) that modifies Der EngA GTPase function. May play a role in ribosome biogenesis (By similarity)
AH4AK4_0205	ENOG4105XCT	Protein of unknown function (DUF2489)
AH4AK4_0206	ENOG4105D4P	Coproporphyrinogen iii oxidase
AH4AK4_0207	ENOG4105EKD	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism (By similarity)
AH4AK4_0208	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
AH4AK4_0209	ENOG4105CUX	Signal transduction histidine kinase
AH4AK4_0211	ENOG4105C5F	glutamine synthetase
AH4AK4_0213	ENOG4107S2Z	UPF0761 membrane protein
AH4AK4_0214	ENOG4108YYA	Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine (By similarity)
AH4AK4_0216	ENOG4105SUU	thioesterase domain
AH4AK4_0218	ENOG4105CB5	ATP-dependent DNA helicase recG
AH4AK4_0219	ENOG4105JIM	Phosphatidylserine synthase
AH4AK4_0220	ENOG4105C6Z	Gluconate
AH4AK4_0221	ENOG4108Z67	carbohydrate kinase, thermoresistant glucokinase family
AH4AK4_0222	ENOG4105C01	Dihydroxy-acid dehydratase
AH4AK4_0223	ENOG4108UHU	Aldolase
AH4AK4_0226	ENOG4105DIQ	Transcriptional regulator
AH4AK4_0229	ENOG41063SB	peptidase
AH4AK4_0230	ENOG4105CJI	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
AH4AK4_0231	ENOG4107YZP	Rhodanese domain protein
AH4AK4_0232	ENOG4105IX2	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA (By similarity)
AH4AK4_0233	ENOG4105CSF	NADPH-dependent glycerol-3-phosphate dehydrogenase
AH4AK4_0234	ENOG4107RUK	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins (By similarity)
AH4AK4_0235	ENOG4105MJ2	Competence protein
AH4AK4_0236	ENOG4105D3C	The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters (By similarity)
AH4AK4_0239	ENOG4105BZM	domain protein
AH4AK4_0241	ENOG4108RRZ	Transcription elongation factor GreB
AH4AK4_0242	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
AH4AK4_0243	ENOG4105E0F	Histidine kinase
AH4AK4_0245	ENOG4108Z10	Involved in the binding of tRNA to the ribosomes (By similarity)
AH4AK4_0246	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
AH4AK4_0247	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
AH4AK4_0248	ENOG41080KG	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
AH4AK4_0249	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
AH4AK4_0251	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
AH4AK4_0252	ENOG4108R70	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity)
AH4AK4_0253	ENOG41083MP	50s ribosomal protein l29
AH4AK4_0254	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
AH4AK4_0255	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
AH4AK4_0256	ENOG4105KAR	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity)
AH4AK4_0257	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
AH4AK4_0258	ENOG4105VBI	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
AH4AK4_0259	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
AH4AK4_0260	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
AH4AK4_0261	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
AH4AK4_0262	ENOG4105VPB	50S ribosomal protein L30
AH4AK4_0263	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
AH4AK4_0264	ENOG4105CGG	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity)
AH4AK4_0266	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
AH4AK4_0267	ENOG4105CTF	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
AH4AK4_0268	ENOG4108ZT0	50S ribosomal protein l17
AH4AK4_0273	ENOG4108K2R	Glutathione-regulated potassium-efflux system ancillary protein
AH4AK4_0274	ENOG4108W5M	transcriptional regulator
AH4AK4_0275	ENOG4105EMU	Dehydrogenase
AH4AK4_0278	ENOG4105CUG	Oligopeptidase b
AH4AK4_0284	ENOG4107FS9	Membrane
AH4AK4_0287	ENOG4105JQN	Transcriptional regulator
AH4AK4_0290	ENOG4105VVZ	metal-binding protein
AH4AK4_0291	ENOG41076UM	multiple antibiotic resistance (MarC)-related protein
AH4AK4_0295	ENOG4105CHQ	Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella (By similarity)
AH4AK4_0297	ENOG4107RZC	phospholipase d
AH4AK4_0299	ENOG4105EJ2	Transcriptional regulator
AH4AK4_0300	ENOG4108Y73	Membrane
AH4AK4_0302	ENOG4106H78	methyltransferase
AH4AK4_0303	ENOG4105CCP	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
AH4AK4_0304	ENOG4105CAK	Cell division ATP-binding protein ftsE
AH4AK4_0305	ENOG4105CRP	Part of the ABC transporter FtsEX involved in
AH4AK4_0306	ENOG4105DEK	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
AH4AK4_0307	ENOG41077A9	carbonic anhydrase
AH4AK4_0308	ENOG4105CZE	histidine utilization repressor
AH4AK4_0309	ENOG4105CI2	imidazolone-5-propionate hydrolase
AH4AK4_0310	ENOG41088SP	formiminoglutamate hydrolase
AH4AK4_0311	ENOG4105CGP	Urocanate hydratase
AH4AK4_0312	ENOG4105C84	Histidine ammonia-lyase
AH4AK4_0313	ENOG4105EWV	Sodium calcium exchanger membrane region
AH4AK4_0314	ENOG4107XTP	(EAL) domain protein
AH4AK4_0322	ENOG4105GVR	general secretion pathway protein D
AH4AK4_0326	ENOG4105D7Q	type ii secretion system
AH4AK4_0329	ENOG4106855	Competence protein
AH4AK4_0334	ENOG4105DFF	Rod shape-determining protein mreb
AH4AK4_0335	ENOG4105N3I	Involved in formation and maintenance of cell shape (By similarity)
AH4AK4_0336	ENOG4105VQ7	Rod shape-determining protein MreD
AH4AK4_0337	ENOG4108Z03	MAF-like protein
AH4AK4_0338	ENOG4105C03	ribonuclease
AH4AK4_0339	ENOG4105QD6	exported protein
AH4AK4_0341	ENOG4105D1U	peptidase U62 modulator of DNA gyrase
AH4AK4_0344	ENOG4105CSH	Transporter
AH4AK4_0346	ENOG4105CGZ	zinc metallopeptidase
AH4AK4_0350	ENOG4105EEQ	Na H antiporter
AH4AK4_0351	ENOG4105C3R	Methionine synthase
AH4AK4_0353	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
AH4AK4_0355	ENOG4105ETX	regulatoR
AH4AK4_0358	ENOG4107Y8H	Aerolysin toxin
AH4AK4_0359	ENOG4105CBF	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction (By similarity)
AH4AK4_0360	ENOG4108UV6	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity)
AH4AK4_0361	ENOG4105D06	uba thif-type nad fad binding protein
AH4AK4_0363	ENOG4105CA8	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity)
AH4AK4_0364	ENOG4105D41	biosynthesis protein thiH
AH4AK4_0366	ENOG4108Z9I	-acetyltransferase
AH4AK4_0367	ENOG4105EQK	-acetyltransferase
AH4AK4_0368	ENOG4108WEF	Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1B (PBP1b) (By similarity)
AH4AK4_0370	ENOG4105BZU	Histidine kinase
AH4AK4_0371	ENOG4108TPP	exopolysaccharide synthesis
AH4AK4_0373	ENOG4105N0V	mono-oxygenase ydhR
AH4AK4_0374	ENOG4105KVH	Transcriptional regulator
AH4AK4_0378	ENOG4105E0K	tonB-dependent siderophore receptor
AH4AK4_0379	ENOG4108RTV	Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol (By similarity)
AH4AK4_0380	ENOG4105FCK	Membrane
AH4AK4_0381	ENOG4105CBT	Fructose-1,6-bisphosphatase
AH4AK4_0382	ENOG4105KRS	Proteinase inhibitor
AH4AK4_0383	ENOG410601J	HemY protein
AH4AK4_0384	ENOG4105ECF	c-methyltransferase
AH4AK4_0385	ENOG41076E6	Uroporphyrinogen-III Synthase
AH4AK4_0386	ENOG4105D6W	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity)
AH4AK4_0388	ENOG4107T0K	Adenylate cyclase
AH4AK4_0389	ENOG4106CJB	Phospholipase Carboxylesterase
AH4AK4_0390	ENOG4105XQ6	frataxin-like protein
AH4AK4_0392	ENOG4105CU5	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity)
AH4AK4_0393	ENOG4105E4Z	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan (By similarity)
AH4AK4_0395	ENOG4108IYS	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
AH4AK4_0396	ENOG4105DFC	had-superfamily hydrolase, subfamily ia, variant
AH4AK4_0398	ENOG4108Z86	Glutamine amidotransferase
AH4AK4_0399	ENOG410667J	hydrolase
AH4AK4_0401	ENOG4107K5X	Membrane-bound metal-dependent hydrolase
AH4AK4_0402	ENOG4108I62	cina-like protein
AH4AK4_0404	ENOG4105CVG	Homoserine O-transsuccinylase
AH4AK4_0406	ENOG4108YXU	transcriptional regulator AsnC family
AH4AK4_0407	ENOG4105E0M	Sulfatase
AH4AK4_0410	ENOG4105KT7	mgtC SapB transporter
AH4AK4_0414	ENOG4105EMU	Dehydrogenase
AH4AK4_0418	ENOG4108I6A	alcohol dehydrogenase
AH4AK4_0420	ENOG4108IQK	o-acetylhomoserine
AH4AK4_0426	ENOG4107IFA	Lipase (EC 3.1.1.3)
AH4AK4_0429	ENOG4108UB4	uncharacterized protein ygjQ
AH4AK4_0430	ENOG4107MM9	BNR Asp-box repeat-containing protein
AH4AK4_0431	ENOG4105CEY	Amp-dependent synthetase and ligase
AH4AK4_0432	ENOG4105DNI	Converts SHCHC to OSB (By similarity)
AH4AK4_0433	ENOG4108IPT	Naphthoate synthase
AH4AK4_0434	ENOG4107J5P	Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC). Is also able to catalyze the hydrolysis of the thioester bond in palmitoyl-CoA in vitro (By similarity)
AH4AK4_0435	ENOG4105C4A	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC) (By similarity)
AH4AK4_0436	ENOG4105E4F	Isochorismate synthase
AH4AK4_0437	ENOG4105EIS	1,4-dihydroxy-2-naphthoate octaprenyltransferase
AH4AK4_0438	ENOG4105D22	carbon starvation protein
AH4AK4_0439	ENOG4105VCD	cytoplasmic protein
AH4AK4_0440	ENOG4105CKI	cobalamin synthesis protein
AH4AK4_0445	ENOG4105C1J	atp-dependent rna helicase
AH4AK4_0447	ENOG4105D9N	nucleoside
AH4AK4_0448	ENOG4107VGF	ig domain protein group 2 domain protein
AH4AK4_0450	ENOG4108UPT	UPF0178 protein
AH4AK4_0455	ENOG4105E61	Mannitol repressor protein
AH4AK4_0456	ENOG4107SQ3	mannitol-1-phosphate 5-dehydrogenase
AH4AK4_0457	ENOG4105CTS	PTS system mannitol-specific
AH4AK4_0459	ENOG4108IEC	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction (By similarity)
AH4AK4_0460	ENOG4105CXD	Specific inhibitor of chromosomal initiation of replication in vitro. Binds the three 13-mers in the origin (oriC) to block initiation of replication (By similarity)
AH4AK4_0461	ENOG4105NNS	Autoinducer synthesis protein
AH4AK4_0462	ENOG4105VJY	transcriptional regulator
AH4AK4_0463	ENOG4108ZUB	Lysine exporter protein (Lyse ygga)
AH4AK4_0464	ENOG4107RNS	bifunctional 2',3'-cyclic nucleotide 2'-phosphodiesterase 3'-nucleotidase periplasmic
AH4AK4_0465	ENOG4105D1S	lipid A biosynthesis
AH4AK4_0467	ENOG4105DW0	Catalyzes the ADP transfer to D-glycero-D-manno-heptose 1-phosphate, yielding ADP-D,D-heptose (By similarity)
AH4AK4_0468	ENOG4105DFG	type I secretion outer membrane protein
AH4AK4_0469	ENOG41087AY	ADP-Ribose pyrophosphatase
AH4AK4_0470	ENOG4108SX3	cytoplasmic protein
AH4AK4_0471	ENOG41070EG	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes (By similarity)
AH4AK4_0472	ENOG4105IPS	esterase
AH4AK4_0476	ENOG4105Y49	secretion protein, HlyD family
AH4AK4_0477	ENOG4105DSW	Fusaric acid resistance protein
AH4AK4_0479	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
AH4AK4_0480	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
AH4AK4_0489	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
AH4AK4_0491	ENOG4105N2G	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
AH4AK4_0496	ENOG4107S7E	1-acyl-sn-glycerol-3-phosphate acyltransferase
AH4AK4_0497	ENOG41087YS	Phage shock protein A
AH4AK4_0500	ENOG41082IR	Excinuclease ABC C subunit domain protein
AH4AK4_0502	ENOG4108RG0	uracil-dna glycosylase
AH4AK4_0504	ENOG4105ETT	transcriptional Regulator, LysR family
AH4AK4_0505	ENOG4105FAV	ABC, transporter
AH4AK4_0506	ENOG4105FDK	ABC transporter
AH4AK4_0507	ENOG4105NXV	High-affinity zinc uptake system protein
AH4AK4_0511	ENOG4105DR5	peptidase
AH4AK4_0517	ENOG4105D86	that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity)
AH4AK4_0519	ENOG4107TH8	cina domain protein
AH4AK4_0520	ENOG4105C68	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity)
AH4AK4_0522	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
AH4AK4_0523	ENOG4105CFH	Aspartokinase
AH4AK4_0524	ENOG4105VM8	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding (By similarity)
AH4AK4_0531	ENOG41061WM	D-Alanyl-D-Alanine
AH4AK4_0532	ENOG4106W5V	Membrane
AH4AK4_0534	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
AH4AK4_0535	ENOG4105MYG	DNA polymerase iii, chi subunit
AH4AK4_0536	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
AH4AK4_0537	ENOG4108M8S	permease YjgP YjgQ family protein
AH4AK4_0538	ENOG4108K5H	permease YjgP YjgQ family protein
AH4AK4_0541	ENOG4105BZU	Histidine kinase
AH4AK4_0542	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
AH4AK4_0547	ENOG4105EYA	deoxyribonuclease
AH4AK4_0548	ENOG4105D9N	nucleoside
AH4AK4_0550	ENOG4105FCI	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate (By similarity)
AH4AK4_0551	ENOG4105CMW	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis (By similarity)
AH4AK4_0552	ENOG4105CZG	Phosphotransfer between the C1 and C5 carbon atoms of pentose (By similarity)
AH4AK4_0553	ENOG4105D3A	purine nucleoside phosphorylase DeoD-type
AH4AK4_0555	ENOG4108NST	exported protein
AH4AK4_0557	ENOG4105EAC	phosphoserine phosphatase
AH4AK4_0560	ENOG4105DNJ	May play a role in the repair of endogenous alkylation damage (By similarity)
AH4AK4_0562	ENOG4108ZVW	Anti-RNA polymerase sigma 70 factor
AH4AK4_0563	ENOG4105K70	DNA-binding protein
AH4AK4_0566	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
AH4AK4_0567	ENOG4105MYN	Zinc uptake regulation protein
AH4AK4_0570	ENOG4105CWM	branched-chain amino acid transport system II carrier protein
AH4AK4_0571	ENOG4107S47	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC) (By similarity)
AH4AK4_0572	ENOG4105C1J	atp-dependent rna helicase
AH4AK4_0573	ENOG4105D1Q	UPF0246 protein
AH4AK4_0574	ENOG4105CZX	twitching motility protein
AH4AK4_0575	ENOG4105CZX	twitching motility protein
AH4AK4_0576	ENOG4105DFA	alanine racemase domain protein
AH4AK4_0577	ENOG4105II7	pyrroline-5-carboxylate reductase
AH4AK4_0578	ENOG4108VIA	integral membrane protein
AH4AK4_0579	ENOG4105VZ9	UPF0235 protein
AH4AK4_0583	ENOG4105XTV	UPF0231 protein
AH4AK4_0584	ENOG4108IXP	Carbohydrate diacid transcriptional activator CdaR
AH4AK4_0585	ENOG4107QQ0	gntp family
AH4AK4_0586	ENOG4105BZW	Glycerate kinase
AH4AK4_0589	ENOG4105HEI	LysR family (Transcriptional regulator
AH4AK4_0590	ENOG4105D9N	nucleoside
AH4AK4_0592	ENOG4108YZN	class I peptide chain release factor
AH4AK4_0593	ENOG4108YZA	Nitrogen regulatory protein pii
AH4AK4_0594	ENOG4107QKW	extracellular solute-binding protein family 1
AH4AK4_0596	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
AH4AK4_0597	ENOG4105EZR	dyp-type peroxidase family protein
AH4AK4_0598	ENOG410682Y	Regulates arginine biosynthesis genes (By similarity)
AH4AK4_0599	ENOG4105E5Z	arginine transporter ATP-binding subunit
AH4AK4_0600	ENOG4106PMH	Extracellular solute-binding protein family 3
AH4AK4_0601	ENOG4105GBT	ABC transporter
AH4AK4_0603	ENOG4105DMR	ABC, transporter
AH4AK4_0604	ENOG4105C80	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
AH4AK4_0605	ENOG4108UV7	flagellar protein motX
AH4AK4_0606	ENOG4105CJJ	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity)
AH4AK4_0608	ENOG4108JU6	CBS domain protein
AH4AK4_0609	ENOG4106KVJ	cytochrome C assembly protein
AH4AK4_0610	ENOG4105CB9	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
AH4AK4_0611	ENOG4105K5M	30s ribosomal protein S16
AH4AK4_0612	ENOG4108ZR6	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity)
AH4AK4_0613	ENOG4105D6X	Specifically methylates guanosine-37 in various tRNAs (By similarity)
AH4AK4_0614	ENOG4108YY1	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity)
AH4AK4_0617	ENOG4105EJF	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity)
AH4AK4_0618	ENOG4108HRM	phosphoenolpyruvate--protein phosphotransferase
AH4AK4_0619	ENOG4105C3B	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity)
AH4AK4_0620	ENOG4105C0V	Provides the sole de novo source of dTMP for DNA biosynthesis (By similarity)
AH4AK4_0621	ENOG4105DRC	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity)
AH4AK4_0623	ENOG41063Z6	transcriptional regulator, lysR family
AH4AK4_0624	ENOG41080HT	Transcriptional regulator, arsr family
AH4AK4_0625	ENOG4105KQV	Binds directly to 16S ribosomal RNA (By similarity)
AH4AK4_0626	ENOG4105CJR	Integral membrane protein (MviN
AH4AK4_0627	ENOG4105DTN	riboflavin biosynthesis protein ribF
AH4AK4_0628	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
AH4AK4_0629	ENOG4105M02	This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity)
AH4AK4_0630	ENOG41090X3	Peptidyl-prolyl cis-trans isomerase
AH4AK4_0631	ENOG4105C48	Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) (By similarity)
AH4AK4_0632	ENOG4106855	Competence protein
AH4AK4_0638	ENOG4105C4K	Nad synthetase
AH4AK4_0639	ENOG4108YZA	Nitrogen regulatory protein pii
AH4AK4_0641	ENOG4106762	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD) (By similarity)
AH4AK4_0642	ENOG4106TD9	Diguanylate cyclase
AH4AK4_0643	ENOG4105C40	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity)
AH4AK4_0644	ENOG4105C2N	RNA methyltransferase TrmH family group 3
AH4AK4_0646	ENOG4107YB6	acetyltransferase, (GNAT) family
AH4AK4_0648	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
AH4AK4_0649	ENOG4105C56	H( )-stimulated, divalent metal cation uptake system (By similarity)
AH4AK4_0650	ENOG4108ZDX	Binds together with S18 to 16S ribosomal RNA (By similarity)
AH4AK4_0651	ENOG4105VH8	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity)
AH4AK4_0652	ENOG4105K9Q	Binds to the 23S rRNA (By similarity)
AH4AK4_0653	ENOG4105DP0	ferredoxin-NADP reductase
AH4AK4_0658	ENOG4105DQ4	alcohol dehydrogenase
AH4AK4_0659	ENOG4105W39	Membrane
AH4AK4_0661	ENOG4105D9M	gamma-glutamylcysteine synthetase
AH4AK4_0662	ENOG4105DS2	Anaerobic c4-dicarboxylate transporter
AH4AK4_0663	ENOG4108IJ0	Aspartate ammonia-lyase
AH4AK4_0664	ENOG4108YH1	overproduction of this protein in Escherichia coli inhibits the F plasmid-mediated exclusion of bacteriophage T7
AH4AK4_0666	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
AH4AK4_0667	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
AH4AK4_0669	ENOG4105BZU	Histidine kinase
AH4AK4_0671	ENOG4105D3G	Pseudouridine synthase
AH4AK4_0672	ENOG4105BZK	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair (By similarity)
AH4AK4_0678	ENOG4105DE7	Sulfate ABC transporter periplasmic sulfate-binding protein
AH4AK4_0680	ENOG4108I5D	sulfate abc transporter
AH4AK4_0681	ENOG4105ECW	sulfate abc transporter
AH4AK4_0682	ENOG4108IJ6	ABC transporter
AH4AK4_0683	ENOG4107R11	Transcriptional regulator
AH4AK4_0685	ENOG4108M1A	Chitin-binding protein
AH4AK4_0692	ENOG4105G0K	glycine radical enzyme YjjI family
AH4AK4_0693	ENOG41076CZ	activating enzyme
AH4AK4_0696	ENOG4105CGF	Aromatic amino acid aminotransferase
AH4AK4_0697	ENOG4105D1V	cellulose synthase operon protein YhjU
AH4AK4_0699	ENOG4105UTS	cellulose synthase operon protein YhjQ
AH4AK4_0700	ENOG4107QZ7	Cellulose synthase catalytic subunit
AH4AK4_0701	ENOG4107EEX	Cellulose synthase regulator protein
AH4AK4_0702	ENOG4105K2Z	endo-1,4-d-glucanase (EC 3.2.1.4)
AH4AK4_0703	ENOG4105EJG	cellulose synthase
AH4AK4_0709	ENOG4108V1J	Has antioxidant activity. Could remove peroxides or H(2)O(2) (By similarity)
AH4AK4_0710	ENOG4105C1J	atp-dependent rna helicase
AH4AK4_0713	ENOG4107RHT	methyl-accepting chemotaxis sensory transducer with Pas Pac sensor
AH4AK4_0715	ENOG4107QSI	ABC, transporter
AH4AK4_0717	ENOG4105EQK	-acetyltransferase
AH4AK4_0718	ENOG4106WH9	Protein of unknown function (DUF2753)
AH4AK4_0719	ENOG4105E39	Enoyl-CoA hydratase
AH4AK4_0722	ENOG4108RZ4	Short-chain dehydrogenase reductase Sdr
AH4AK4_0723	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
AH4AK4_0724	ENOG4105C8Q	Methyl-accepting chemotaxis
AH4AK4_0725	ENOG4105KA4	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity)
AH4AK4_0726	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
AH4AK4_0727	ENOG4105C4M	(Ubiquinol oxidase) subunit I
AH4AK4_0728	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
AH4AK4_0730	ENOG4105KJB	cyd operon protein YbgE
AH4AK4_0731	ENOG4107YD3	Thioesterase
AH4AK4_0732	ENOG4105E02	MotA TolQ exbB proton channel
AH4AK4_0733	ENOG4105M8F	Biopolymer transport protein exbD tolR
AH4AK4_0735	ENOG4107R6Y	Involved in the TonB-independent uptake of proteins (By similarity)
AH4AK4_0736	ENOG4105KCK	Peptidoglycan-associated lipoprotein
AH4AK4_0737	ENOG4105UFD	tol-pal system protein YbgF
AH4AK4_0742	ENOG4105C8Q	Methyl-accepting chemotaxis
AH4AK4_0743	ENOG4105D0I	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate (By similarity)
AH4AK4_0744	ENOG4105DSB	aldose 1-epimerase
AH4AK4_0745	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
AH4AK4_0746	ENOG4107RTM	4-alpha-glucanotransferase (EC 2.4.1.25)
AH4AK4_0747	ENOG4105C9C	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity)
AH4AK4_0749	ENOG4105E0X	reductase
AH4AK4_0752	ENOG4105CJH	Alcohol dehydrogenase zinc-binding domain protein
AH4AK4_0753	ENOG4105K56	Transcriptional regulator
AH4AK4_0756	ENOG4105EW9	transcriptional regulator AsnC family
AH4AK4_0760	ENOG410667J	hydrolase
AH4AK4_0763	ENOG4105C8J	)-transporter
AH4AK4_0764	ENOG4105C8J	)-transporter
AH4AK4_0767	ENOG4107SQD	Transcriptional regulator, GntR family
AH4AK4_0772	ENOG4108IQE	Amp-dependent synthetase and ligase
AH4AK4_0774	ENOG41080E2	ribosomal-protein-alanine acetyltransferase
AH4AK4_0777	ENOG4105EV2	VWA domain protein interacting with AAA ATPase
AH4AK4_0778	ENOG4105BZU	Histidine kinase
AH4AK4_0779	ENOG4105BZU	Histidine kinase
AH4AK4_0780	ENOG4105C8A	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP (By similarity)
AH4AK4_0783	ENOG4108MJ3	acetyltransferase
AH4AK4_0784	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
AH4AK4_0789	ENOG4105DWY	Agmatine deiminase
AH4AK4_0790	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
AH4AK4_0792	ENOG4107YH7	Beta-lactamase (EC 3.5.2.6)
AH4AK4_0797	ENOG4105C1J	atp-dependent rna helicase
AH4AK4_0798	ENOG4105BZU	Histidine kinase
AH4AK4_0799	ENOG4107Y60	(LipO)protein
AH4AK4_0801	ENOG4106B0W	Curli production assembly transport component CsgG
AH4AK4_0805	ENOG4107V4F	S-adenosyl-l-methionine hydroxide adenosyltransferase
AH4AK4_0816	ENOG4105VY0	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters (By similarity)
AH4AK4_0817	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
AH4AK4_0820	ENOG4107V40	secretion protein, HlyD family
AH4AK4_0826	ENOG4105I93	response regulator
AH4AK4_0827	ENOG4105DUX	Transporter
AH4AK4_0828	ENOG4105C3Y	UTP-glucose-1-phosphate uridylyltransferase
AH4AK4_0829	ENOG41083P1	competence protein ComEA helix-hairpin-helix repeat protein
AH4AK4_0830	ENOG4108RNI	3'(2')5'-bisphosphate nucleotidase
AH4AK4_0831	ENOG4105K9H	YciI-like protein
AH4AK4_0832	ENOG4107835	probably involved in intracellular septation (By similarity)
AH4AK4_0833	ENOG4105DY8	decarboxylase
AH4AK4_0835	ENOG4108UT2	hemolysin iii
AH4AK4_0836	ENOG4105D0C	transport protein
AH4AK4_0838	ENOG4105EV4	Multidrug resistance protein mdtH
AH4AK4_0842	ENOG4105D9U	N-acetyltransferase
AH4AK4_0844	ENOG4105XEP	YhcH YjgK YiaL family protein
AH4AK4_0846	ENOG4105CUY	Mechanosensitive ion channel
AH4AK4_0847	ENOG4107N1Q	ErfK YbiS YcfS YnhG family protein
AH4AK4_0848	ENOG4105CK7	Sodium proline symporter
AH4AK4_0855	ENOG4105D6S	protein involved in catabolism of external DNA
AH4AK4_0857	ENOG4105C5H	ABC transporter
AH4AK4_0858	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
AH4AK4_0859	ENOG4105FCK	Membrane
AH4AK4_0860	ENOG4107R88	Chemotaxis protein (CheV)
AH4AK4_0861	ENOG4108UJV	acyl-CoA thioesterase i
AH4AK4_0862	ENOG4108I0Y	(ABC) transporter
AH4AK4_0863	ENOG4105CV6	ABC transporter, permease
AH4AK4_0864	ENOG4105ECP	epimerase
AH4AK4_0865	ENOG4105BZU	Histidine kinase
AH4AK4_0866	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
AH4AK4_0867	ENOG4105IIU	Aminopeptidase
AH4AK4_0868	ENOG4105CZ1	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity)
AH4AK4_0869	ENOG41090ED	Protein with unknown function (DUF469)
AH4AK4_0870	ENOG4105CSV	Glutaminase
AH4AK4_0871	ENOG4107RM6	sulfurtransferase
AH4AK4_0872	ENOG4105E3R	(LipO)protein
AH4AK4_0873	ENOG4108W78	Pfam:DUF1017
AH4AK4_0874	ENOG4108MDC	(LipO)protein
AH4AK4_0878	ENOG4105SUV	lipoprotein YgdR
AH4AK4_0883	ENOG4105BZ1	(ABC) transporter
AH4AK4_0889	ENOG4105KQT	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome (By similarity)
AH4AK4_0890	ENOG4105BZU	Histidine kinase
AH4AK4_0894	ENOG4105VYA	Uncharacterized conserved protein (DUF2132)
AH4AK4_0895	ENOG4105DJ4	phosphatidylserine decarboxylase
AH4AK4_0897	ENOG4108RBP	3'-to-5' exoribonuclease specific for small oligoribonucleotides (By similarity)
AH4AK4_0903	ENOG4105VEQ	Cold shock protein
AH4AK4_0905	ENOG4105C8Q	Methyl-accepting chemotaxis
AH4AK4_0907	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
AH4AK4_0918	ENOG4109015	Biopolymer transport protein exbD tolR
AH4AK4_0925	ENOG4108I5X	binding-protein-dependent transport systems inner membrane Component
AH4AK4_0926	ENOG4108IYQ	Binding-protein-dependent transport systems inner membrane component
AH4AK4_0929	ENOG4108JQ7	(ABC) transporter
AH4AK4_0931	ENOG4105CIN	aminoacyl-histidine dipeptidase
AH4AK4_0933	ENOG4105DYA	Acts on guanine, xanthine and to a lesser extent hypoxanthine (By similarity)
AH4AK4_0934	ENOG4105V1F	Fermentation respiration switch protein
AH4AK4_0935	ENOG4108UVK	Binds to the sigma-S subunit of RNA polymerase, activating expression of sigma-S-regulated genes. Stimulates RNA polymerase holoenzyme formation and may bind to several other sigma factors, such as sigma-70 and sigma-32 (By similarity)
AH4AK4_0938	ENOG4105C2S	Catalyzes the NADPH dependent reduction of L-gamma- glutamyl 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate (By similarity)
AH4AK4_0944	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
AH4AK4_0947	ENOG4105DG7	nitrate ABC transporter
AH4AK4_0948	ENOG4105D7T	ABC transporter
AH4AK4_0949	ENOG4107QZF	nitrite reductase NADPH large subunit
AH4AK4_0950	ENOG4107QZF	nitrite reductase NADPH large subunit
AH4AK4_0952	ENOG4105DD7	kinase (PfkB family
AH4AK4_0953	ENOG4105D53	Catalyzes the hydrolysis of pseudouridine 5'-phosphate (PsiMP) to ribose 5-phosphate and uracil (By similarity)
AH4AK4_0955	ENOG4105CA0	peroxidase
AH4AK4_0958	ENOG4108RIR	Molybdenum cofactor biosynthesis protein
AH4AK4_0961	ENOG4105DWK	Membrane
AH4AK4_0962	ENOG4107XM3	UPF0442 protein
AH4AK4_0964	ENOG4108IJ7	Glycine betaine
AH4AK4_0965	ENOG4108HQS	Glycine betaine
AH4AK4_0966	ENOG4105GIJ	Glycine betaine
AH4AK4_0967	ENOG4105ET3	Reduction of activated sulfate into sulfite (By similarity)
AH4AK4_0968	ENOG4105ET1	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate (By similarity)
AH4AK4_0969	ENOG4107EER	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity)
AH4AK4_0970	ENOG4107TIF	Phenazine biosynthesis protein, PhzF family
AH4AK4_0971	ENOG4105CRK	lysyL-tRNA synthetase
AH4AK4_0972	ENOG4105CG1	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA (By similarity)
AH4AK4_0973	ENOG4105C8Q	Methyl-accepting chemotaxis
AH4AK4_0974	ENOG4105D6U	Sodium Glutamate Symporter
AH4AK4_0975	ENOG4105HDK	L-asparaginase
AH4AK4_0976	ENOG4105VUT	cytoplasmic protein
AH4AK4_0980	ENOG4105D07	Signal peptide peptidase, SppA
AH4AK4_0981	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
AH4AK4_0982	ENOG41069NU	Nitroreductase
AH4AK4_0984	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
AH4AK4_0985	ENOG4105CIS	alcohol dehydrogenase
AH4AK4_0986	ENOG4105HEI	LysR family (Transcriptional regulator
AH4AK4_0987	ENOG4105CI1	PTS System
AH4AK4_0988	ENOG4108IA2	Sodium pantothenate symporter
AH4AK4_0989	ENOG4105RG0	Membrane
AH4AK4_0990	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
AH4AK4_0991	ENOG4105KM4	Acetyl-CoA carboxylase, biotin carboxyl carrier protein
AH4AK4_0992	ENOG4108Z38	Catalyzes a trans-dehydration via an enolate intermediate (By similarity)
AH4AK4_0993	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
AH4AK4_0994	ENOG4105BZU	Histidine kinase
AH4AK4_0996	ENOG4109039	Involved in the biogenesis of TorA. Acts on TorA before the insertion of the molybdenum cofactor and, as a result, probably favors a conformation of the apoenzyme that is competent for acquiring the cofactor (By similarity)
AH4AK4_0997	ENOG4108EM1	reductase
AH4AK4_0998	ENOG4105CUW	cytochrome C-TYPE protein
AH4AK4_0999	ENOG4106WF9	DNA-binding transcriptional regulator TorR
AH4AK4_1000	ENOG4108SV3	Tmao reductase system periplasmic protein tort
AH4AK4_1001	ENOG4105BZU	Histidine kinase
AH4AK4_1003	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
AH4AK4_1004	ENOG4108Z11	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes (By similarity)
AH4AK4_1005	ENOG4105D1W	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity)
AH4AK4_1008	ENOG4108UTT	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity)
AH4AK4_1009	ENOG4107YIM	Involved in the transcription termination process (By similarity)
AH4AK4_1010	ENOG4105CG2	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity)
AH4AK4_1011	ENOG4108ZAI	phosphatidylglycerophosphatase a
AH4AK4_1013	ENOG4108JQ6	ABC transporter
AH4AK4_1015	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
AH4AK4_1017	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
AH4AK4_1018	ENOG4105CTB	Polyprenyl synthetase
AH4AK4_1019	ENOG41067QG	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
AH4AK4_1020	ENOG4105E14	MotA TolQ exbB proton channel
AH4AK4_1021	ENOG4107XSU	flagellar motor protein motb
AH4AK4_1022	ENOG4105K3G	Periplasmic Protein
AH4AK4_1023	ENOG4105CY3	ABC transporter, permease
AH4AK4_1024	ENOG4108IJ6	ABC transporter
AH4AK4_1034	ENOG4105T2N	Domain of unknown function (DUF2382)
AH4AK4_1036	ENOG4108UKH	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
AH4AK4_1038	ENOG4105HBR	Rna-binding protein
AH4AK4_1039	ENOG4105F7M	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit (By similarity)
AH4AK4_1040	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
AH4AK4_1041	ENOG4105EEI	dihydropteroate synthase
AH4AK4_1042	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
AH4AK4_1043	ENOG4105CP7	Triose-phosphate isomerase
AH4AK4_1047	ENOG4105K7D	Required for maturation of 30S ribosomal subunits (By similarity)
AH4AK4_1048	ENOG4105CHV	Transcription elongation factor NusA
AH4AK4_1049	ENOG4107QHU	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
AH4AK4_1050	ENOG4105KG7	Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity)
AH4AK4_1051	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
AH4AK4_1052	ENOG4105K77	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity)
AH4AK4_1053	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
AH4AK4_1054	ENOG4105E5W	Transporter
AH4AK4_1055	ENOG41090EX	DsrE family
AH4AK4_1057	ENOG4105K5D	4fe-4S ferredoxin iroN-sulfur binding
AH4AK4_1058	ENOG4105CFP	Peptidase U32
AH4AK4_1059	ENOG4107N1Q	ErfK YbiS YcfS YnhG family protein
AH4AK4_1062	ENOG4105D1U	peptidase U62 modulator of DNA gyrase
AH4AK4_1064	ENOG41071R3	Low-potential electron donor to a number of redox enzymes (By similarity)
AH4AK4_1065	ENOG41071R3	Low-potential electron donor to a number of redox enzymes (By similarity)
AH4AK4_1066	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
AH4AK4_1067	ENOG4105M2E	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell (By similarity)
AH4AK4_1069	ENOG4105C2R	Single-stranded-DNA-specific exonuclease (RecJ)
AH4AK4_1071	ENOG4108IUB	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
AH4AK4_1073	ENOG4105C0G	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity)
AH4AK4_1075	ENOG4108BDP	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity)
AH4AK4_1076	ENOG4108Z43	UPF0250 protein
AH4AK4_1077	ENOG4105DZ1	carboxypeptidase
AH4AK4_1078	ENOG4105K6T	rare lipoprotein A
AH4AK4_1079	ENOG4105CVE	Lytic murein transglycosylase
AH4AK4_1080	ENOG4105CNI	cell division protein FtsW
AH4AK4_1081	ENOG4105CJN	penicillin-binding protein
AH4AK4_1082	ENOG4108UXA	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA (By similarity)
AH4AK4_1083	ENOG4105KEM	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation (By similarity)
AH4AK4_1084	ENOG4108Z1W	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity)
AH4AK4_1087	ENOG4105C8T	Leucyl-tRNA synthetase
AH4AK4_1088	ENOG4107PAI	alpha helical protein
AH4AK4_1089	ENOG4105CE8	Transfers the fatty acyl group on membrane lipoproteins (By similarity)
AH4AK4_1090	ENOG4108JU5	Magnesium and cobalt efflux protein
AH4AK4_1091	ENOG4105KGE	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA (By similarity)
AH4AK4_1092	ENOG4105C9A	Phoh family
AH4AK4_1093	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
AH4AK4_1094	ENOG4105EAK	ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family
AH4AK4_1095	ENOG4106XMA	In vivo, quickly hydrolyzes the ureidoacrylate peracid to avoid toxicity, but can also hydrolyzes ureidoacrylate that is formed spontaneously from ureidoacrylate peracid. One of the products of hydrolysis, carbamate, hydrolyzes spontaneously, thereby releasing one of the pyrimidine rings nitrogen atoms as ammonia and one of its carbons as CO2 (By similarity)
AH4AK4_1096	ENOG4105F04	LysR family Transcriptional regulator
AH4AK4_1098	ENOG4105EVE	HAD-superfamily hydrolase subfamily IA variant 3
AH4AK4_1100	ENOG4105BZU	Histidine kinase
AH4AK4_1102	ENOG4105C5I	Dehydrogenase
AH4AK4_1104	ENOG4108R5S	membrane
AH4AK4_1105	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
AH4AK4_1107	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
AH4AK4_1109	ENOG4105DHQ	Histidine kinase
AH4AK4_1110	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
AH4AK4_1112	ENOG4108IXY	short-chain dehydrogenase reductase
AH4AK4_1114	ENOG4108IQE	Amp-dependent synthetase and ligase
AH4AK4_1116	ENOG4105DA6	Catalyzes the conversion of 5-methoxyuridine (mo5U) to uridine-5-oxyacetic acid (cmo5U) at position 34 in tRNA. May also participate in the methylation of uridine-5-oxyacetic acid (cmo5U) to uridine-5-oxyacetic acid methyl ester (mcmo5U) (By similarity)
AH4AK4_1117	ENOG4105T0Z	Conserved Protein
AH4AK4_1118	ENOG4108VP9	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane (By similarity)
AH4AK4_1119	ENOG4108WJH	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane (By similarity)
AH4AK4_1120	ENOG4105E33	succinate dehydrogenase
AH4AK4_1123	ENOG4105C8Q	Methyl-accepting chemotaxis
AH4AK4_1124	ENOG4108QXE	glycerophosphoryl diester phosphodiesterase
AH4AK4_1126	ENOG4105EGS	Mechanosensitive ion channel
AH4AK4_1128	ENOG4105DR5	peptidase
AH4AK4_1131	ENOG4108VEV	chaperone
AH4AK4_1132	ENOG4105CW0	outer membrane usher protein
AH4AK4_1133	ENOG4108VEV	chaperone
AH4AK4_1136	ENOG4105EJC	lysr family transcriptional regulator
AH4AK4_1139	ENOG4105C5Q	Transcriptional regulator
AH4AK4_1140	ENOG4108JQC	penicillin-binding protein 1A
AH4AK4_1145	ENOG4105E4G	Type IV pilus
AH4AK4_1146	ENOG4105KHV	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
AH4AK4_1147	ENOG4105D49	3-dehydroquinate synthase
AH4AK4_1149	ENOG4105DFE	Dna adenine methylase
AH4AK4_1150	ENOG4105DJV	ribulose-phosphate 3-epimerase
AH4AK4_1151	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
AH4AK4_1152	ENOG4105C31	Tryptophanyl-tRNA synthetase
AH4AK4_1155	ENOG4105C8Y	Acetylornithine aminotransferase
AH4AK4_1156	ENOG4105F4X	arginine
AH4AK4_1157	ENOG4105C26	Dehydrogenase
AH4AK4_1159	ENOG4107VXZ	Hydrolase
AH4AK4_1161	ENOG4107QF7	multi-drug
AH4AK4_1162	ENOG4105C5H	ABC transporter
AH4AK4_1164	ENOG4105CG3	alpha amylase, catalytic region
AH4AK4_1167	ENOG4105N5Z	UPF0267 protein
AH4AK4_1168	ENOG4107QWE	)-transporter
AH4AK4_1177	ENOG4105C3G	gtp-binding protein
AH4AK4_1178	ENOG4108ZPD	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity)
AH4AK4_1179	ENOG4105CGH	5'-nucleotidase
AH4AK4_1180	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
AH4AK4_1183	ENOG4105C1U	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein (By similarity)
AH4AK4_1184	ENOG4105C7E	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) (By similarity)
AH4AK4_1185	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
AH4AK4_1186	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
AH4AK4_1188	ENOG41063JG	Transcriptional regulator
AH4AK4_1189	ENOG4105CXR	Phospho-2-dehydro-3-deoxyoctonate aldolase
AH4AK4_1190	ENOG4105CK2	sodium dicarboxylate symporter
AH4AK4_1191	ENOG4108VKA	Acts as a radical domain for damaged PFL and possibly other radical proteins (By similarity)
AH4AK4_1192	ENOG4105D5S	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine (By similarity)
AH4AK4_1195	ENOG4105CW3	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
AH4AK4_1196	ENOG4105BZG	amino acid carrier protein
AH4AK4_1200	ENOG4107Y66	Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity)
AH4AK4_1201	ENOG4108UJU	UPF0301 protein
AH4AK4_1202	ENOG4105D7Z	glutathione synthase
AH4AK4_1203	ENOG4105QF0	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity)
AH4AK4_1205	ENOG4105GPY	SprT protein
AH4AK4_1206	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
AH4AK4_1207	ENOG4105CV1	Transketolase (EC 2.2.1.1)
AH4AK4_1208	ENOG4105KME	endoribonuclease L-psp
AH4AK4_1210	ENOG4105KEG	ribosomal-protein-alanine acetyltransferase
AH4AK4_1212	ENOG4105ED7	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling (By similarity)
AH4AK4_1214	ENOG4105DR5	peptidase
AH4AK4_1215	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
AH4AK4_1216	ENOG4107WCA	isomerase
AH4AK4_1218	ENOG4108V1U	phospholipid-binding protein
AH4AK4_1219	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
AH4AK4_1222	ENOG4105C87	Aminotransferase class I and II
AH4AK4_1224	ENOG4105C5Q	Transcriptional regulator
AH4AK4_1225	ENOG4105UBK	short-chain dehydrogenase reductase
AH4AK4_1226	ENOG4105ERU	peptidase
AH4AK4_1227	ENOG4105EY2	Catalyzes the hydrolysis of N(2)-succinylarginine into N(2)-succinylornithine, ammonia and CO(2) (By similarity)
AH4AK4_1228	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
AH4AK4_1231	ENOG4107RHT	methyl-accepting chemotaxis sensory transducer with Pas Pac sensor
AH4AK4_1232	ENOG4105E2D	ec 3.2.1.52
AH4AK4_1233	ENOG4105RD7	BadF BadG BcrA BcrD
AH4AK4_1236	ENOG4108JQ7	(ABC) transporter
AH4AK4_1238	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
AH4AK4_1242	ENOG4105CBM	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 (By similarity)
AH4AK4_1246	ENOG4105VQ0	flagellar hook-basal body complex protein fliE
AH4AK4_1247	ENOG4105C1F	The M ring may be actively involved in energy transduction (By similarity)
AH4AK4_1248	ENOG4105CS3	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
AH4AK4_1250	ENOG4108JIR	Flagellum-specific ATP synthase
AH4AK4_1254	ENOG4105D24	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
AH4AK4_1255	ENOG4105DD5	Flagellar motor switch protein
AH4AK4_1256	ENOG4105VTB	flagellar biosynthesis protein fliO
AH4AK4_1257	ENOG4105CN7	Flagellar biosynthetic protein FliP
AH4AK4_1258	ENOG4105VS8	Flagellar biosynthetic protein fliq
AH4AK4_1259	ENOG4105D19	Role in flagellar biosynthesis (By similarity)
AH4AK4_1260	ENOG4105D00	flagellar biosynthetic protein flhB
AH4AK4_1262	ENOG4105D7B	Flagellar biosynthesis protein flha
AH4AK4_1263	ENOG4105FZW	flagellar biosynthesis regulator FlhF
AH4AK4_1265	ENOG4105DN4	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
AH4AK4_1266	ENOG4108VYJ	response regulator receiver protein
AH4AK4_1267	ENOG4108KCC	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P) (By similarity)
AH4AK4_1268	ENOG4105CBS	Chea signal transduction histidine kinase
AH4AK4_1269	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
AH4AK4_1270	ENOG4105E14	MotA TolQ exbB proton channel
AH4AK4_1271	ENOG4108SEK	ompa motb domain protein
AH4AK4_1272	ENOG4107QJE	Chromosome Partitioning Protein
AH4AK4_1274	ENOG4108V3W	Chemotaxis protein, CheW
AH4AK4_1277	ENOG4105CA5	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes (By similarity)
AH4AK4_1279	ENOG41060IM	Heme exporter protein
AH4AK4_1280	ENOG4105X3C	heme exporter protein
AH4AK4_1281	ENOG4108ZKK	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH (By similarity)
AH4AK4_1282	ENOG4105DA4	cytochrome c-type biogenesis protein
AH4AK4_1283	ENOG4107QX9	Thiol disulfide interChange protein
AH4AK4_1284	ENOG4105KWW	Biogenesis protein
AH4AK4_1285	ENOG4108QUE	repeat-containing protein
AH4AK4_1286	ENOG410903C	(LipO)protein
AH4AK4_1287	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
AH4AK4_1288	ENOG4105M2J	Glutaredoxin
AH4AK4_1292	ENOG4108S7T	Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) (By similarity)
AH4AK4_1293	ENOG4107R11	Transcriptional regulator
AH4AK4_1298	ENOG4108YYD	acetyltransferase
AH4AK4_1301	ENOG4108UH4	Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity)
AH4AK4_1302	ENOG4108Z1B	Cyclase dehydrase
AH4AK4_1303	ENOG4105VDB	UPF0125 protein
AH4AK4_1304	ENOG4105K4T	epimerase
AH4AK4_1305	ENOG4105YRI	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
AH4AK4_1306	ENOG4105C0A	alcohol dehydrogenase
AH4AK4_1307	ENOG4107SXA	Phosphorylase
AH4AK4_1308	ENOG4105D3G	Pseudouridine synthase
AH4AK4_1309	ENOG4105DU0	nucleoside hydrolase
AH4AK4_1312	ENOG4105RX8	Protein of unknown function (DUF1523)
AH4AK4_1314	ENOG410829K	Lysine exporter protein (Lyse ygga)
AH4AK4_1316	ENOG4105C3N	Participates in control of cell volume in low-osmolarity conditions (By similarity)
AH4AK4_1319	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
AH4AK4_1320	ENOG4105KUZ	arsenate reductase
AH4AK4_1323	ENOG4105CEE	C4-dicarboxylate transporter
AH4AK4_1324	ENOG4105CH2	amidohydrolase
AH4AK4_1326	ENOG4105DS2	Anaerobic c4-dicarboxylate transporter
AH4AK4_1328	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
AH4AK4_1329	ENOG4105EMU	Dehydrogenase
AH4AK4_1331	ENOG4105C5S	asparaginyl-tRNA synthetase
AH4AK4_1334	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
AH4AK4_1336	ENOG4105CZF	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism (By similarity)
AH4AK4_1337	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
AH4AK4_1338	ENOG410626R	Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity)
AH4AK4_1339	ENOG4105E78	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity)
AH4AK4_1340	ENOG4105D0M	Protease HtpX homolog
AH4AK4_1341	ENOG4105QVC	MOSC domain-containing protein
AH4AK4_1341	ENOG4105QVC	MOSC domain-containing protein
AH4AK4_1344	ENOG4105Z2P	Protein of unknown function (DUF465)
AH4AK4_1346	ENOG4105UQX	Mate efflux family protein
AH4AK4_1350	ENOG4105C6T	cysteine synthase
AH4AK4_1353	ENOG4107Z3H	Transcriptional regulator, TetR family
AH4AK4_1354	ENOG4107RGH	Aldehyde dehydrogenase
AH4AK4_1356	ENOG4107TT5	NLP P60 protein
AH4AK4_1357	ENOG4105C5Q	Transcriptional regulator
AH4AK4_1361	ENOG4105PFA	Catalyzes the conversion of 5-hydroxyuridine (ho5U) to 5-methoxyuridine (mo5U) at position 34 in tRNA (By similarity)
AH4AK4_1362	ENOG4105DA6	Catalyzes the conversion of 5-methoxyuridine (mo5U) to uridine-5-oxyacetic acid (cmo5U) at position 34 in tRNA. May also participate in the methylation of uridine-5-oxyacetic acid (cmo5U) to uridine-5-oxyacetic acid methyl ester (mcmo5U) (By similarity)
AH4AK4_1363	ENOG41081XQ	Conserved Protein
AH4AK4_1364	ENOG4105C9M	aspartyl-trna synthetase
AH4AK4_1365	ENOG4105CDY	transcriptional regulatory protein
AH4AK4_1366	ENOG4105DIJ	Phosphoethanolamine transferase
AH4AK4_1367	ENOG4105E2R	ROK family
AH4AK4_1368	ENOG4105CE4	GlcNAc 6-P deacetylase
AH4AK4_1369	ENOG4105CKA	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion (By similarity)
AH4AK4_1370	ENOG4105CI1	PTS System
AH4AK4_1371	ENOG4105E2D	ec 3.2.1.52
AH4AK4_1374	ENOG4105CE2	Aldehyde oxidase and xanthine dehydrogenase, molybdopterin binding
AH4AK4_1376	ENOG4105C7W	Xanthine dehydrogenase
AH4AK4_1377	ENOG4105CX6	glutaminyL-tRNA synthetase
AH4AK4_1378	ENOG41090R7	Ferric uptake
AH4AK4_1380	ENOG4105MHQ	Low-potential electron donor to a number of redox enzymes (By similarity)
AH4AK4_1381	ENOG4105NNH	LexA regulated protein
AH4AK4_1383	ENOG4105EV9	Alpha Beta Hydrolase
AH4AK4_1384	ENOG4107CDU	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated (By similarity)
AH4AK4_1385	ENOG4107QIX	Phosphoglucomutase (EC 5.4.2.2
AH4AK4_1388	ENOG4105CVE	Lytic murein transglycosylase
AH4AK4_1389	ENOG4108T9J	Cdp-alcohol phosphatidyltransferase
AH4AK4_1390	ENOG4108VGW	abc transporter atp-binding protein
AH4AK4_1392	ENOG4105VNH	ABC transporter solute-binding protein
AH4AK4_1394	ENOG4107ZN8	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity (By similarity)
AH4AK4_1396	ENOG4107UUG	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity)
AH4AK4_1398	ENOG4105CFU	surface antigen
AH4AK4_1399	ENOG4105MA0	exported protein
AH4AK4_1403	ENOG4108WPH	sigma 54 modulation protein ribosomal protein S30EA
AH4AK4_1404	ENOG4105BZU	Histidine kinase
AH4AK4_1405	ENOG4107SC1	transglycosylase
AH4AK4_1406	ENOG41060NJ	transcriptional regulator
AH4AK4_1409	ENOG4105NAU	thioesterase Superfamily protein
AH4AK4_1411	ENOG4107NA1	Endonuclease Exonuclease phosphatase
AH4AK4_1412	ENOG4105E9H	Lytic Murein transglycosylase
AH4AK4_1413	ENOG4108RW0	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
AH4AK4_1414	ENOG4105D1A	Methyltransferase
AH4AK4_1415	ENOG4108UMW	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
AH4AK4_1416	ENOG4107RZZ	dna polymerase iii epsilon subunit
AH4AK4_1418	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
AH4AK4_1419	ENOG4107QPN	acyl-Coa dehydrogenase
AH4AK4_1420	ENOG4105F55	Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate (By similarity)
AH4AK4_1421	ENOG4105E7A	Glutamine amidotransferase
AH4AK4_1423	ENOG4105CHW	UPF0052 protein
AH4AK4_1425	ENOG4105BZU	Histidine kinase
AH4AK4_1428	ENOG4105WH1	Two component transcriptional regulator luxr family
AH4AK4_1429	ENOG4105BZU	Histidine kinase
AH4AK4_1430	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
AH4AK4_1433	ENOG4107QIW	Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity)
AH4AK4_1434	ENOG4108BGM	Quinol dehydrogenase periplasmic component
AH4AK4_1435	ENOG4105GXZ	Ferredoxin-type protein NapH
AH4AK4_1437	ENOG4105CUW	cytochrome C-TYPE protein
AH4AK4_1438	ENOG4108RIR	Molybdenum cofactor biosynthesis protein
AH4AK4_1439	ENOG4108YXW	Together with MoaA, is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
AH4AK4_1440	ENOG4105M00	molybdopterin converting factor, subunit 1
AH4AK4_1441	ENOG4108ZAF	Molybdopterin
AH4AK4_1442	ENOG4108S6J	ABC transporter, periplasmic molybdate-binding protein
AH4AK4_1443	ENOG4105E0C	molybdate abc transporter
AH4AK4_1444	ENOG4105CGB	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system (By similarity)
AH4AK4_1445	ENOG410832A	alpha/beta hydrolase fold
AH4AK4_1448	ENOG4105D06	uba thif-type nad fad binding protein
AH4AK4_1449	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
AH4AK4_1450	ENOG4105EUJ	GTP cyclohydrolase i
AH4AK4_1451	ENOG4105C8Q	Methyl-accepting chemotaxis
AH4AK4_1452	ENOG4105CKU	formyltetrahydrofolate synthetase
AH4AK4_1454	ENOG4105CC0	LysR family Transcriptional regulator
AH4AK4_1455	ENOG4108YYC	ycei family
AH4AK4_1457	ENOG4105C3E	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine (By similarity)
AH4AK4_1460	ENOG4105D42	Cleaves the N-terminal amino acid of tripeptides (By similarity)
AH4AK4_1463	ENOG4105DP5	Catalyzes the biosynthesis of agmatine from arginine (By similarity)
AH4AK4_1464	ENOG4108QY5	Ferric enterobactin transport protein
AH4AK4_1465	ENOG4105BZU	Histidine kinase
AH4AK4_1466	ENOG4108R4U	Hnh endonuclease
AH4AK4_1468	ENOG4105I9P	Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor (By similarity)
AH4AK4_1469	ENOG4105D82	Glutamate dehydrogenase
AH4AK4_1470	ENOG4105FE9	pseudouridine synthase
AH4AK4_1471	ENOG4105DJ2	Major Facilitator Superfamily
AH4AK4_1475	ENOG4106428	Protein of unknown function (DUF2496)
AH4AK4_1479	ENOG4108Q2J	Inner membrane protein YebE
AH4AK4_1481	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
AH4AK4_1482	ENOG4105C4M	(Ubiquinol oxidase) subunit I
AH4AK4_1483	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
AH4AK4_1485	ENOG4105F27	Major Facilitator
AH4AK4_1487	ENOG4105CV8	reductase
AH4AK4_1491	ENOG4105HEI	LysR family (Transcriptional regulator
AH4AK4_1492	ENOG4108JQ0	Key enzyme in the regulation of glycerol uptake and metabolism (By similarity)
AH4AK4_1493	ENOG4105D8C	Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity)
AH4AK4_1494	ENOG4105CXY	transporter
AH4AK4_1495	ENOG4105E98	transcriptional regulator DeoR family
AH4AK4_1497	ENOG4105C6V	Glycerol-3-phosphate dehydrogenase
AH4AK4_1498	ENOG4106MZZ	glycerophosphoryl diester phosphodiesterase
AH4AK4_1499	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
AH4AK4_1502	ENOG4108WFC	UPF0438 protein yifE
AH4AK4_1503	ENOG4108QSZ	General inhibitor of pancreatic serine proteases inhibits chymotrypsin, trypsin, elastases, factor X, kallikrein as well as a variety of other proteases (By similarity)
AH4AK4_1507	ENOG4105CUG	Oligopeptidase b
AH4AK4_1508	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
AH4AK4_1509	ENOG4105E68	Sulfatase
AH4AK4_1510	ENOG4105PAN	UPF0352 protein
AH4AK4_1511	ENOG4106V8H	Nucleoid-associated protein
AH4AK4_1513	ENOG4107FKK	extracellular solute-binding protein family 1
AH4AK4_1514	ENOG4105D56	permease protein
AH4AK4_1515	ENOG4105EG2	ABC transporter, permease
AH4AK4_1516	ENOG4108IJ9	(ABC) transporter
AH4AK4_1517	ENOG4105CSR	polyphosphate kinase 2
AH4AK4_1521	ENOG41082K8	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Interacts with IscS and stimulates its activity. Then, accepts a sulfur from IscS and transfers it in turn to TusD (By similarity)
AH4AK4_1523	ENOG4105ERG	peptidase m48, ste24p
AH4AK4_1525	ENOG4105K89	arsenate reductase
AH4AK4_1527	ENOG4105CI2	imidazolone-5-propionate hydrolase
AH4AK4_1528	ENOG4108ZYK	Acyl carrier protein phosphodiesterase
AH4AK4_1529	ENOG4106PMH	Extracellular solute-binding protein family 3
AH4AK4_1530	ENOG4105DYB	Isoaspartyl dipeptidase
AH4AK4_1531	ENOG4105DWU	Membrane
AH4AK4_1533	ENOG4108JEH	abc transporter atp-binding protein
AH4AK4_1534	ENOG4106PMH	Extracellular solute-binding protein family 3
AH4AK4_1535	ENOG4105DSP	amino acid AbC transporter
AH4AK4_1536	ENOG4106YG3	ABC transporter
AH4AK4_1538	ENOG4105F1A	Pyruvate formate-lyase
AH4AK4_1539	ENOG4105BZU	Histidine kinase
AH4AK4_1540	ENOG4107QMW	pyridine nucleotide-disulfide oxidoreductase
AH4AK4_1543	ENOG4105J12	Multidrug resistance protein mdtN
AH4AK4_1546	ENOG4105DN3	alpha-2-macroglobulin domain protein
AH4AK4_1547	ENOG4108JQB	penicillin-binding protein 1C
AH4AK4_1549	ENOG4105D8I	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS (By similarity)
AH4AK4_1551	ENOG4105EN6	Membrane
AH4AK4_1553	ENOG4105I03	Flagellin
AH4AK4_1554	ENOG4105I03	Flagellin
AH4AK4_1555	ENOG41063QE	flagellar protein FlaG
AH4AK4_1557	ENOG4105MQ3	flagellar protein FliS
AH4AK4_1565	ENOG4107TY6	Acylneuraminate cytidylyltransferase
AH4AK4_1567	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
AH4AK4_1568	ENOG4105C5E	polysaccharide biosynthesis protein
AH4AK4_1571	ENOG4105DUF	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively (By similarity)
AH4AK4_1574	ENOG4108N3W	hemolysin secretion protein
AH4AK4_1575	ENOG4108UYE	Lactoylglutathione lyase
AH4AK4_1576	ENOG4105CSM	endonuclease III
AH4AK4_1577	ENOG4105DZB	Electron transport complex
AH4AK4_1578	ENOG4108UQQ	Electron transport complex
AH4AK4_1580	ENOG4105D6A	Electron transport complex
AH4AK4_1582	ENOG4108R3D	Electron transport complex
AH4AK4_1583	ENOG4105DGN	Electron transport complex
AH4AK4_1584	ENOG4108PCN	EamA-like transporter family
AH4AK4_1586	ENOG4107SDU	Methyl-accepting chemotaxis
AH4AK4_1589	ENOG4105RKW	reductase (By
AH4AK4_1590	ENOG4105CSX	c4-dicarboxylate anaerobic carrier
AH4AK4_1591	ENOG4105CHM	Aminotransferase
AH4AK4_1594	ENOG41090BQ	Glutaredoxin
AH4AK4_1595	ENOG4106HRJ	d-alanyl-d-alanine carboxypeptidase
AH4AK4_1596	ENOG4105CFI	type iii restriction protein res subunit
AH4AK4_1598	ENOG4105EFX	secretion protein, HlyD family
AH4AK4_1599	ENOG4105KK7	inner membrane protein YiaW
AH4AK4_1600	ENOG4105EGS	Mechanosensitive ion channel
AH4AK4_1602	ENOG4108NEV	two component transcriptional regulator, LytTR family
AH4AK4_1603	ENOG4108HRK	Histidine kinase
AH4AK4_1604	ENOG4105CPI	Metal Dependent Phosphohydrolase
AH4AK4_1605	ENOG4108EKI	Dehydrogenase
AH4AK4_1606	ENOG4105EZI	multiple antibiotic resistance (MarC)-related protein
AH4AK4_1607	ENOG4107QSI	ABC, transporter
AH4AK4_1608	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
AH4AK4_1609	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
AH4AK4_1610	ENOG4105C3U	ABC transporter
AH4AK4_1611	ENOG4108JQ7	(ABC) transporter
AH4AK4_1613	ENOG4105DU1	integral membrane protein, terc
AH4AK4_1614	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
AH4AK4_1617	ENOG4105CK2	sodium dicarboxylate symporter
AH4AK4_1620	ENOG4105CD3	dihydroorotase
AH4AK4_1622	ENOG4108NVR	Methyl-accepting chemotaxis
AH4AK4_1623	ENOG4105K59	histidine triad (HIT) protein
AH4AK4_1631	ENOG4107QN8	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
AH4AK4_1633	ENOG4107RAB	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
AH4AK4_1636	ENOG4105CKW	Inner membrane protein yedI
AH4AK4_1637	ENOG4105DPN	Oligoendopeptidase f
AH4AK4_1638	ENOG4105DPN	Oligoendopeptidase f
AH4AK4_1640	ENOG4105CEP	NADH dehydrogenase
AH4AK4_1641	ENOG4105K8R	UPF0145 protein
AH4AK4_1642	ENOG4107T7U	Sulfatase
AH4AK4_1644	ENOG4105CFH	Aspartokinase
AH4AK4_1646	ENOG4107QZM	n-acetylglutamate synthase
AH4AK4_1648	ENOG4107QXP	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
AH4AK4_1656	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
AH4AK4_1660	ENOG4105C2C	drug resistance transporter, Bcr CflA
AH4AK4_1664	ENOG4105CVN	desaturase
AH4AK4_1675	ENOG4105CHH	sulfate transporter
AH4AK4_1678	ENOG4108WC9	type VI secretion system effector, hcp1 family
AH4AK4_1680	ENOG4105CS6	Rhs element vgr protein
AH4AK4_1695	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
AH4AK4_1702	ENOG4105CS6	Rhs element vgr protein
AH4AK4_1705	ENOG4105E3S	small subunit
AH4AK4_1706	ENOG4105QA4	4Fe-4S Ferredoxin, iron-sulfur binding domain protein
AH4AK4_1707	ENOG4105CJ5	hydrogenase 2 b cytochrome subunit
AH4AK4_1708	ENOG4105DPX	Hydrogenase, large subunit
AH4AK4_1709	ENOG4108USZ	hydrogenase
AH4AK4_1710	ENOG4108WGS	hydrogenase 2-specific chaperone
AH4AK4_1712	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
AH4AK4_1713	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
AH4AK4_1716	ENOG4105EFJ	Part of the ABC transporter complex NikABCDE involved in nickel import. Responsible for energy coupling to the transport system (By similarity)
AH4AK4_1717	ENOG4107RSS	Hydrogenase accessory protein HypB
AH4AK4_1720	ENOG4105WMM	Probably plays a role in a hydrogenase nickel cofactor insertion step (By similarity)
AH4AK4_1721	ENOG4105C45	hydrogenase expression formation protein (HypE)
AH4AK4_1722	ENOG4105CQS	hydrogenase expression formation protein HypD
AH4AK4_1723	ENOG4105WRB	Hydrogenase assembly chaperone hypC hupF
AH4AK4_1727	ENOG4105DFH	Transport of potassium into the cell (By similarity)
AH4AK4_1730	ENOG4105F3K	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity)
AH4AK4_1731	ENOG4105CJX	Molecular chaperone. Has ATPase activity (By similarity)
AH4AK4_1732	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
AH4AK4_1733	ENOG4105CFX	Catalyzes the ferrous insertion into protoporphyrin IX (By similarity)
AH4AK4_1736	ENOG4107RE1	Inosine-guanosine kinase
AH4AK4_1738	ENOG4105C8Q	Methyl-accepting chemotaxis
AH4AK4_1742	ENOG4105BZU	Histidine kinase
AH4AK4_1743	ENOG4107QQ4	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans (By similarity)
AH4AK4_1746	ENOG4105F3T	(LipO)protein
AH4AK4_1748	ENOG4108IQC	2,3-dihydroxybenzoate-AMP ligase
AH4AK4_1749	ENOG4105WQI	isochorismatase
AH4AK4_1750	ENOG4105CEY	Amp-dependent synthetase and ligase
AH4AK4_1751	ENOG4105X17	23-dihydro-2,3-dihydroxybenzoate dehydrogenase
AH4AK4_1753	ENOG4105CEY	Amp-dependent synthetase and ligase
AH4AK4_1755	ENOG4108TSE	Transferase
AH4AK4_1756	ENOG4105E0A	ABC, transporter
AH4AK4_1757	ENOG4105TVJ	transport system, permease
AH4AK4_1758	ENOG4105DQ5	transport system permease protein
AH4AK4_1759	ENOG4105D05	Receptor
AH4AK4_1762	ENOG4105QZU	Inner membrane protein YfeZ
AH4AK4_1763	ENOG4107QUT	magnesium and cobalt transport protein CorA
AH4AK4_1764	ENOG4105DWH	electron transfer flavoprotein-ubiquinone oxidoreductase
AH4AK4_1765	ENOG4105BZJ	Electron transfer flavoprotein
AH4AK4_1767	ENOG4105C10	Electron transfer flavoprotein
AH4AK4_1768	ENOG4107QM1	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine (By similarity)
AH4AK4_1769	ENOG4105CMY	5-enolpyruvylshikimate-3-phosphate synthase
AH4AK4_1770	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
AH4AK4_1771	ENOG4105EE5	Membrane protein terC
AH4AK4_1773	ENOG4105MH2	YfcL protein
AH4AK4_1774	ENOG4108IQE	Amp-dependent synthetase and ligase
AH4AK4_1775	ENOG4107T42	This enzyme scavenge exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis (By similarity)
AH4AK4_1776	ENOG41067MG	lrgb family
AH4AK4_1778	ENOG4107R49	K07407 alpha-galactosidase EC 3.2.1.22
AH4AK4_1780	ENOG4105CJB	Exodeoxyribonuclease I
AH4AK4_1781	ENOG4105DDT	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP (By similarity)
AH4AK4_1784	ENOG4105CHM	Aminotransferase
AH4AK4_1785	ENOG4105ETT	transcriptional Regulator, LysR family
AH4AK4_1786	ENOG4105CAC	Catalyzes the conversion of L-arabinose to L-ribulose (By similarity)
AH4AK4_1788	ENOG4105EF1	ribulokinase
AH4AK4_1789	ENOG4105DMK	Periplasmic binding protein LacI transcriptional regulator
AH4AK4_1791	ENOG4105CNN	ABC, transporter
AH4AK4_1794	ENOG4105NRA	50s ribosomal protein l31 type b
AH4AK4_1797	ENOG4108VKG	metal-dependent hydrolase
AH4AK4_1800	ENOG4105CEE	C4-dicarboxylate transporter
AH4AK4_1802	ENOG4105CWG	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34 (By similarity)
AH4AK4_1803	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
AH4AK4_1806	ENOG4105BZN	citrate synthase
AH4AK4_1807	ENOG4108UTY	succinate dehydrogenase, cytochrome b556 subunit
AH4AK4_1808	ENOG4105N1I	succinate dehydrogenase, hydrophobic membrane anchor protein
AH4AK4_1809	ENOG4105C00	Succinate dehydrogenase (Flavoprotein subunit)
AH4AK4_1810	ENOG4105E33	succinate dehydrogenase
AH4AK4_1811	ENOG4105C7P	2-oxoglutarate dehydrogenase, E1
AH4AK4_1812	ENOG4105C7S	Dehydrogenase
AH4AK4_1813	ENOG4105CMV	Succinyl-CoA synthetase subunit beta
AH4AK4_1814	ENOG4105CH8	Succinyl-CoA ligase ADP-forming subunit alpha
AH4AK4_1815	ENOG4105ECQ	AraC Family Transcriptional Regulator
AH4AK4_1817	ENOG4105CJP	fad dependent oxidoreductase
AH4AK4_1818	ENOG4107RCV	ABC transporter, permease
AH4AK4_1820	ENOG4105C4Y	ABC transporter
AH4AK4_1823	ENOG4107STF	Involved in phosphonate degradation (By similarity)
AH4AK4_1824	ENOG4108JPW	Aminotransferase
AH4AK4_1825	ENOG4108KAZ	Involved in phosphonate degradation (By similarity)
AH4AK4_1826	ENOG4105C6N	Formate acetyltransferase
AH4AK4_1827	ENOG4105TMB	Formate nitrite transporter
AH4AK4_1828	ENOG4105DDY	UPF0142 protein ycaO
AH4AK4_1830	ENOG4105KPY	Small multidrug resistance protein
AH4AK4_1831	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
AH4AK4_1832	ENOG4105VEQ	Cold shock protein
AH4AK4_1833	ENOG4105KAE	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation (By similarity)
AH4AK4_1834	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
AH4AK4_1835	ENOG4105K9U	however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity)
AH4AK4_1836	ENOG4105DWA	May conjugate Arg from its aminoacyl-tRNA to the N- termini of proteins containing an N-terminal aspartate or glutamate
AH4AK4_1837	ENOG4108R4Z	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine (By similarity)
AH4AK4_1838	ENOG4107MBR	17 kDa surface antigen
AH4AK4_1839	ENOG4105BZU	Histidine kinase
AH4AK4_1840	ENOG4105C3M	thioredoxin reductase
AH4AK4_1841	ENOG4105DCF	alanine dehydrogenase
AH4AK4_1843	ENOG4105EW9	transcriptional regulator AsnC family
AH4AK4_1844	ENOG4105CNU	cell division protein FtsK
AH4AK4_1845	ENOG4107Y7W	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) (By similarity)
AH4AK4_1846	ENOG4105D1H	recombination factor protein RarA
AH4AK4_1848	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
AH4AK4_1849	ENOG4105E96	Colicin v production protein
AH4AK4_1850	ENOG4105CBA	glutamine phosphoribosylpyrophosphate amidotransferase
AH4AK4_1851	ENOG4105CS2	ec 3.2.1.21
AH4AK4_1852	ENOG4105C5Y	PTS System
AH4AK4_1853	ENOG4105DDV	Transcriptional regulator (LacI family
AH4AK4_1854	ENOG4105FR9	TRNA-(Ms 2 io 6 A)-hydroxylase
AH4AK4_1855	ENOG4108JQ2	peptide transport system atp-binding protein
AH4AK4_1857	ENOG4108JQ3	Peptide ABC transporter ATP-binding protein
AH4AK4_1859	ENOG4108EU3	peptide transport system, permease
AH4AK4_1860	ENOG4108I5W	peptide transport system, permease protein
AH4AK4_1861	ENOG4108J59	Extracellular solute-binding protein, family 5
AH4AK4_1862	ENOG4105E51	psp operon transcriptional activator
AH4AK4_1863	ENOG41087YS	Phage shock protein A
AH4AK4_1864	ENOG4105YYT	phage shock protein B
AH4AK4_1866	ENOG4105CM6	amino acid regulated cytosolic protein
AH4AK4_1867	ENOG4106K28	UPF0283 membrane protein
AH4AK4_1868	ENOG4105MIR	Phenylalanine 4-monooxygenase
AH4AK4_1869	ENOG41090A4	Pterin carbinolamine dehydratase
AH4AK4_1871	ENOG4108WS1	
AH4AK4_1872	ENOG4108KHX	Diguanylate cyclase
AH4AK4_1873	ENOG41090EK	ompa motb domain protein
AH4AK4_1874	ENOG4105D4P	Coproporphyrinogen iii oxidase
AH4AK4_1875	ENOG4105DVS	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
AH4AK4_1877	ENOG4105SG9	biopolymer transport protein, ExbD
AH4AK4_1880	ENOG4105C9C	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity)
AH4AK4_1883	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
AH4AK4_1884	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
AH4AK4_1887	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
AH4AK4_1890	ENOG4105FQ6	thiopurine methyltransferase
AH4AK4_1891	ENOG4107QXK	peptidase
AH4AK4_1892	ENOG4108BY2	phosphohistidine phosphatase
AH4AK4_1894	ENOG4108IPJ	Membrane
AH4AK4_1895	ENOG4108J59	Extracellular solute-binding protein, family 5
AH4AK4_1896	ENOG4105CZI	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
AH4AK4_1897	ENOG4108JA2	transcriptioN-repair coupling factor
AH4AK4_1899	ENOG4105D60	lipoprotein releasing system transmembrane protein
AH4AK4_1900	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
AH4AK4_1901	ENOG4105D60	lipoprotein releasing system transmembrane protein
AH4AK4_1902	ENOG4105DK2	UPF0207 protein
AH4AK4_1905	ENOG4105DEA	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation
AH4AK4_1906	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
AH4AK4_1907	ENOG4105CHN	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
AH4AK4_1908	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
AH4AK4_1909	ENOG4105K70	DNA-binding protein
AH4AK4_1910	ENOG4105EIN	peptidylprolyl cis-trans isomerase
AH4AK4_1911	ENOG4105C5H	ABC transporter
AH4AK4_1912	ENOG4107QN1	sodium solute
AH4AK4_1913	ENOG41062QD	Membrane
AH4AK4_1916	ENOG41060WC	Enoyl-CoA hydratase
AH4AK4_1917	ENOG4105BZG	amino acid carrier protein
AH4AK4_1920	ENOG4106HK8	GPR1 FUN34 yaaH family protein
AH4AK4_1923	ENOG4105CBH	Hydroxymethylglutaryl-CoA lyase
AH4AK4_1925	ENOG4105E39	Enoyl-CoA hydratase
AH4AK4_1926	ENOG4107QX3	carboxylase
AH4AK4_1927	ENOG4105C1G	acyl-Coa dehydrogenase
AH4AK4_1928	ENOG4105C26	Dehydrogenase
AH4AK4_1929	ENOG4105C1G	acyl-Coa dehydrogenase
AH4AK4_1930	ENOG4105E39	Enoyl-CoA hydratase
AH4AK4_1931	ENOG4105E39	Enoyl-CoA hydratase
AH4AK4_1932	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
AH4AK4_1933	ENOG4105CHR	reductase
AH4AK4_1934	ENOG4105D5Q	Arginine ornithine antiporter
AH4AK4_1935	ENOG4105HF0	Membrane
AH4AK4_1937	ENOG4105D01	(LipO)protein
AH4AK4_1939	ENOG41062B0	ABC transporter, permease
AH4AK4_1940	ENOG4107R9N	ABC transporter
AH4AK4_1941	ENOG4105C2J	ABC transporter
AH4AK4_1942	ENOG4107R5U	Periplasmic binding protein LacI transcriptional regulator
AH4AK4_1946	ENOG4107H9G	Necessary for formate dehydrogenase activity (By similarity)
AH4AK4_1947	ENOG4107QKC	Oxidoreductase alpha (molybdopterin) subunit
AH4AK4_1950	ENOG4105BZU	Histidine kinase
AH4AK4_1951	ENOG4105DND	Transcriptional regulator
AH4AK4_1953	ENOG4105CS2	ec 3.2.1.21
AH4AK4_1954	ENOG4105CHR	reductase
AH4AK4_1955	ENOG4105CBN	LysR family transcriptional regulator
AH4AK4_1959	ENOG4105EFU	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin (By similarity)
AH4AK4_1961	ENOG4105DUM	transcriptional regulator, lysR family
AH4AK4_1963	ENOG4105D1S	lipid A biosynthesis
AH4AK4_1965	ENOG4105D1S	lipid A biosynthesis
AH4AK4_1967	ENOG4105EUB	pirin domain protein
AH4AK4_1970	ENOG4105CQ2	DNA polymerase
AH4AK4_1976	ENOG4107QI1	Mate efflux family protein
AH4AK4_1977	ENOG4105W1I	UPF0253 protein
AH4AK4_1978	ENOG4108R6K	riboflavin synthase, subunit alpha
AH4AK4_1980	ENOG4107UW8	HAD-superfamily hydrolase subfamily IA variant 3
AH4AK4_1981	ENOG4108HH9	Catalyzes two reactions the first one is the production of beta-formyl glycinamide ribonucleotide (GAR) from formate, ATP and beta GAR
AH4AK4_1982	ENOG4108SXK	Transporter Drug Metabolite Exporter family
AH4AK4_1983	ENOG4108V3G	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity)
AH4AK4_1990	ENOG4105XW2	UPF0263 protein
AH4AK4_1991	ENOG4108VKV	Monofunctional biosynthetic peptidoglycan transglycosylase
AH4AK4_1993	ENOG4105VJP	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell (By similarity)
AH4AK4_1994	ENOG4107QMS	site-determining protein
AH4AK4_1995	ENOG4105K7U	Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization (By similarity)
AH4AK4_1996	ENOG4105VNG	YcgL domain-containing protein
AH4AK4_1997	ENOG4105CVE	Lytic murein transglycosylase
AH4AK4_1998	ENOG4105EJQ	L-serine dehydratase
AH4AK4_1999	ENOG4105EJQ	L-serine dehydratase
AH4AK4_2001	ENOG4105NBK	UPF0345 protein
AH4AK4_2002	ENOG4105CK2	sodium dicarboxylate symporter
AH4AK4_2004	ENOG4105CHU	acetyl-coa acetyltransferase
AH4AK4_2005	ENOG4105D58	Diguanylate phosphodiesterase
AH4AK4_2006	ENOG4105CKF	membrane protein involved in aromatic hydrocarbon degradation
AH4AK4_2007	ENOG4105CKF	membrane protein involved in aromatic hydrocarbon degradation
AH4AK4_2010	ENOG4105EMN	RNA polymerase sigma factor
AH4AK4_2017	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
AH4AK4_2018	ENOG4105CHU	acetyl-coa acetyltransferase
AH4AK4_2019	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
AH4AK4_2021	ENOG4108VWS	Yaeq family
AH4AK4_2026	ENOG4105EHG	Permease protein
AH4AK4_2030	ENOG4105BZS	acriflavin resistance protein
AH4AK4_2033	ENOG4108YAB	Invasion protein
AH4AK4_2034	ENOG4107MBR	17 kDa surface antigen
AH4AK4_2036	ENOG4105CEY	Amp-dependent synthetase and ligase
AH4AK4_2039	ENOG4105K8F	Phosphoribosyl-amp cyclohydrolase
AH4AK4_2040	ENOG4105C0S	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity)
AH4AK4_2041	ENOG4105BZU	Histidine kinase
AH4AK4_2043	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
AH4AK4_2044	ENOG4105CJV	Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase
AH4AK4_2045	ENOG4108UJE	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity)
AH4AK4_2047	ENOG4105CIH	Imidazole acetol-phosphate transaminase
AH4AK4_2049	ENOG4105E21	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity)
AH4AK4_2051	ENOG4105DVT	helicase
AH4AK4_2052	ENOG41072GX	Peptidase M22 Glycoprotease
AH4AK4_2054	ENOG4107J5P	Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC). Is also able to catalyze the hydrolysis of the thioester bond in palmitoyl-CoA in vitro (By similarity)
AH4AK4_2055	ENOG4105CEY	Amp-dependent synthetase and ligase
AH4AK4_2058	ENOG4105DXC	membrane
AH4AK4_2060	ENOG4105FBT	Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs (By similarity)
AH4AK4_2061	ENOG4105WD1	Membrane
AH4AK4_2062	ENOG4109003	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity)
AH4AK4_2064	ENOG4107QMP	dna polymerase iii subunits gamma and tau
AH4AK4_2065	ENOG4105KDX	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection (By similarity)
AH4AK4_2066	ENOG4105CHJ	isochorismatase hydrolase
AH4AK4_2067	ENOG4105EUB	pirin domain protein
AH4AK4_2068	ENOG4105JQN	Transcriptional regulator
AH4AK4_2069	ENOG4105DWD	nucleoside recognition domain protein
AH4AK4_2070	ENOG4105WH1	Two component transcriptional regulator luxr family
AH4AK4_2072	ENOG4105CQ7	ATP-dependent helicase
AH4AK4_2074	ENOG4105KW6	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance (By similarity)
AH4AK4_2075	ENOG4105BZU	Histidine kinase
AH4AK4_2076	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
AH4AK4_2077	ENOG4105C5X	domain protein
AH4AK4_2078	ENOG4105CR7	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA (By similarity)
AH4AK4_2079	ENOG4105D4F	Synthesizes selenophosphate from selenide and ATP (By similarity)
AH4AK4_2080	ENOG4105FAT	Acyl-transferase
AH4AK4_2082	ENOG4105DR4	Methyltransferase
AH4AK4_2083	ENOG4108N3W	hemolysin secretion protein
AH4AK4_2084	ENOG4105VSY	K01512 acylphosphatase EC 3.6.1.7
AH4AK4_2086	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
AH4AK4_2087	ENOG4105D1F	ATP-binding protein
AH4AK4_2088	ENOG4105DBI	uridine monophosphokinase
AH4AK4_2089	ENOG4105DHP	deoxycytidine triphosphate deaminase
AH4AK4_2090	ENOG4105CJ3	phosphate transporter
AH4AK4_2091	ENOG4105C03	ribonuclease
AH4AK4_2092	ENOG4105EI2	Pseudouridine synthase
AH4AK4_2093	ENOG4108UHJ	MAF-like protein
AH4AK4_2095	ENOG4105FCQ	metal-binding, possibly nucleic acid-binding protein
AH4AK4_2096	ENOG4105VGS	50s ribosomal protein l32
AH4AK4_2097	ENOG4105C6B	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA (By similarity)
AH4AK4_2098	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
AH4AK4_2099	ENOG4105CJF	Malonyl coA-acyl carrier protein transacylase
AH4AK4_2100	ENOG4105CHR	reductase
AH4AK4_2101	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
AH4AK4_2102	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
AH4AK4_2103	ENOG4105YAZ	4-amino-4-deoxychorismate lyase
AH4AK4_2104	ENOG4105HHA	aminodeoxychorismate lyase
AH4AK4_2105	ENOG4108ZMD	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity)
AH4AK4_2106	ENOG4107QRG	dna polymerase iii
AH4AK4_2107	ENOG4105F8V	Hydrolase, tatD family
AH4AK4_2110	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
AH4AK4_2111	ENOG4105DY2	Paraquat-inducible protein b
AH4AK4_2112	ENOG4105H2K	paraquat-inducible protein a
AH4AK4_2114	ENOG4105X2V	dna damage-inducible protein
AH4AK4_2116	ENOG4105DAN	ATP-dependent protease
AH4AK4_2117	ENOG4108RKI	Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl- ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)- decenoyl-ACP. Can catalyze the dehydratase reaction for beta- hydroxyacyl-ACPs with saturated chain lengths up to 16 0, being most active on intermediate chain length (By similarity)
AH4AK4_2118	ENOG4105WFT	During stationary phase, converts 70S ribosomes to an inactive dimeric form (100S ribosomes) (By similarity)
AH4AK4_2120	ENOG4105C5H	ABC transporter
AH4AK4_2122	ENOG4105C4H	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA (By similarity)
AH4AK4_2123	ENOG4108T7E	Contributes to the efficiency of the cell division process by stabilizing the polymeric form of the cell division protein FtsZ. Acts by promoting interactions between FtsZ protofilaments and suppressing the GTPase activity of FtsZ (By similarity)
AH4AK4_2124	ENOG4107QYT	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor (By similarity)
AH4AK4_2125	ENOG4105C7I	Dehydrogenase
AH4AK4_2127	ENOG4105CD8	aminopeptidase N
AH4AK4_2129	ENOG4105CN1	protease
AH4AK4_2130	ENOG41073DY	may be a structural element that influences the osmotic activation of ProP at a post-translational level (By similarity)
AH4AK4_2131	ENOG4108ZGC	gaf domain protein
AH4AK4_2133	ENOG4105EUH	cytochrome C oxidase, cbb3-type, subunit i
AH4AK4_2136	ENOG4105D6P	C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex (By similarity)
AH4AK4_2141	ENOG4105DS0	Transcriptional regulator, Crp Fnr family
AH4AK4_2142	ENOG4105Q9Y	Universal stress protein
AH4AK4_2143	ENOG4105CB3	Required for the thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32) (By similarity)
AH4AK4_2146	ENOG4108RXX	maleylacetoacetate isomerase
AH4AK4_2147	ENOG4105MRB	Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose (By similarity)
AH4AK4_2148	ENOG4105C2J	ABC transporter
AH4AK4_2149	ENOG4105CNN	ABC, transporter
AH4AK4_2150	ENOG4105E9V	Periplasmic binding protein LacI transcriptional regulator
AH4AK4_2151	ENOG4108RVA	ribokinase
AH4AK4_2152	ENOG4105ETE	Transcriptional regulator (LacI family
AH4AK4_2153	ENOG4105BZU	Histidine kinase
AH4AK4_2155	ENOG4105NDF	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity)
AH4AK4_2158	ENOG4105BZU	Histidine kinase
AH4AK4_2159	ENOG4108ZUF	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
AH4AK4_2160	ENOG4105C6A	phenylalanyl-tRNA synthetase (beta subunit)
AH4AK4_2161	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
AH4AK4_2162	ENOG4108YZX	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity)
AH4AK4_2163	ENOG4108UUX	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity)
AH4AK4_2164	ENOG4105C22	threonyL-tRNA synthetase
AH4AK4_2170	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
AH4AK4_2171	ENOG4108HWB	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
AH4AK4_2172	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
AH4AK4_2173	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
AH4AK4_2174	ENOG4105E05	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
AH4AK4_2175	ENOG4105XPH	Ferredoxin
AH4AK4_2176	ENOG4105CA3	membrane-bound lytic murein transglycosylase
AH4AK4_2177	ENOG4105XZD	Fe-S protein
AH4AK4_2178	ENOG4105DM4	PTS System
AH4AK4_2179	ENOG4105DE4	1-phosphofructokinase
AH4AK4_2180	ENOG4105DTZ	bifunctional PTS system fructose-specific transporter subunit IIA HPr protein
AH4AK4_2181	ENOG4107B7Y	DNA-binding transcriptional regulator FruR
AH4AK4_2182	ENOG4105E0U	tyrosine-specific transport protein
AH4AK4_2189	ENOG4105WJG	Glutathione
AH4AK4_2190	ENOG4105C1J	atp-dependent rna helicase
AH4AK4_2192	ENOG4105D10	5-enolpyruvylshikimate-3-phosphate phospholyase
AH4AK4_2193	ENOG4105C76	Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue (By similarity)
AH4AK4_2194	ENOG4108DG9	Smr protein MutS2
AH4AK4_2201	ENOG4108Z8G	Alkylphosphonate utilization operon protein PhnA
AH4AK4_2204	ENOG4105JAB	phenazine biosynthesis protein, phzf family
AH4AK4_2213	ENOG4105DUC	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division (By similarity)
AH4AK4_2214	ENOG4105DAH	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF (By similarity)
AH4AK4_2215	ENOG4105GHU	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid partitioning. Probably acts via its interaction with MukB and MukE. Overexpression results in anucleate cells. It has a calcium binding activity (By similarity)
AH4AK4_2216	ENOG4106371	Methyltransferase
AH4AK4_2217	ENOG4107S90	membrAne
AH4AK4_2219	ENOG4105CTQ	phosphohexokinase
AH4AK4_2221	ENOG4105CH2	amidohydrolase
AH4AK4_2222	ENOG4105PAD	Hydrolase
AH4AK4_2223	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
AH4AK4_2228	ENOG4105CPB	ATP-dependent endonuclease of the OLD family
AH4AK4_2232	ENOG4105VP0	transcriptional regulator, lysR family
AH4AK4_2233	ENOG4105EJ9	Membrane
AH4AK4_2234	ENOG4106IUH	DTW domain containing protein
AH4AK4_2236	ENOG4105CPF	Cell wall formation (By similarity)
AH4AK4_2239	ENOG4105C1J	atp-dependent rna helicase
AH4AK4_2240	ENOG4105K5X	acetyltransferase
AH4AK4_2242	ENOG4105KK4	UPF0060 membrane protein
AH4AK4_2247	ENOG41061CK	Antibiotic biosynthesis monooxygenase
AH4AK4_2248	ENOG4107XGF	functions in a salvage pathway. Uses pyridoxamine (By similarity)
AH4AK4_2252	ENOG4105D1N	poly(r)-hydroxyalkanoic acid synthase, class
AH4AK4_2254	ENOG4105WQ3	Rna-binding protein
AH4AK4_2257	ENOG4105BZ1	(ABC) transporter
AH4AK4_2258	ENOG4105BZ1	(ABC) transporter
AH4AK4_2259	ENOG4105BZU	Histidine kinase
AH4AK4_2260	ENOG4105K63	Thioredoxin
AH4AK4_2261	ENOG4105C8P	)-transporter
AH4AK4_2263	ENOG4107QQN	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties (By similarity)
AH4AK4_2273	ENOG4105C44	Serine transporter
AH4AK4_2274	ENOG4107QV7	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system) (By similarity)
AH4AK4_2275	ENOG4105C9U	ATP-dependent DNA helicase RecQ
AH4AK4_2276	ENOG4105CYN	Serine protein kinase
AH4AK4_2277	ENOG4106AKX	UPF0229 protein
AH4AK4_2278	ENOG4105ED1	spovr family
AH4AK4_2279	ENOG4105C05	Multifunctional regulator of fatty acid metabolism (By similarity)
AH4AK4_2280	ENOG4105DKR	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity)
AH4AK4_2281	ENOG410635M	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein (By similarity)
AH4AK4_2282	ENOG4105DQR	SNARE associated Golgi
AH4AK4_2284	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
AH4AK4_2286	ENOG4105D0C	transport protein
AH4AK4_2287	ENOG4105E4C	Lytic transglycosylase catalytic
AH4AK4_2291	ENOG4108MRH	transcriptional regulatory protein
AH4AK4_2292	ENOG4105CEQ	signal transduction histidine kinase regulating citrate malate metabolism
AH4AK4_2293	ENOG4105E2R	ROK family
AH4AK4_2294	ENOG4105C8Q	Methyl-accepting chemotaxis
AH4AK4_2295	ENOG4105K5B	UPF0225 protein
AH4AK4_2296	ENOG4107R5Y	anaerobic glycerol-3-phosphate dehydrogenase, subunit A
AH4AK4_2297	ENOG4108KJ0	anaerobic glycerol-3-phosphate dehydrogenase, subunit B
AH4AK4_2298	ENOG4105CHG	glycolate oxidase (iron-sulfur subunit)
AH4AK4_2301	ENOG4105JJ8	Cytochrome c nitrite reductase, pentaheme subunit
AH4AK4_2302	ENOG4105D3S	4Fe-4S Ferredoxin, iron-sulfur binding domain protein
AH4AK4_2303	ENOG4105DVI	reductase, NrfD
AH4AK4_2304	ENOG4105DA4	cytochrome c-type biogenesis protein
AH4AK4_2305	ENOG4107QX9	Thiol disulfide interChange protein
AH4AK4_2306	ENOG4108DMF	Cytochrome C biogenesis protein
AH4AK4_2307	ENOG4108Z4K	mutator MutT protein
AH4AK4_2308	ENOG41061WM	D-Alanyl-D-Alanine
AH4AK4_2309	ENOG4105EXX	Deoxyribodipyrimidine photolyase-related protein
AH4AK4_2310	ENOG4105MWK	D-amino acid dehydrogenase, small subunit
AH4AK4_2313	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
AH4AK4_2315	ENOG4105DSS	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation (By similarity)
AH4AK4_2316	ENOG4105DZ2	Transcriptional regulator
AH4AK4_2320	ENOG4106TD9	Diguanylate cyclase
AH4AK4_2321	ENOG4108BRW	Activates expression of the rhaSR operon in response to L-rhamnose (By similarity)
AH4AK4_2323	ENOG4105JQN	Transcriptional regulator
AH4AK4_2324	ENOG4108RYK	Nad-dependent epimerase dehydratase
AH4AK4_2326	ENOG4105C28	cystathionine
AH4AK4_2327	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
AH4AK4_2331	ENOG4105C1X	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity (By similarity)
AH4AK4_2333	ENOG4108RMJ	sensory transduction regulator
AH4AK4_2335	ENOG4107104	thymidine kinase
AH4AK4_2336	ENOG4107S6Z	Na H antiporter
AH4AK4_2338	ENOG4108WBT	adenosyltransferase
AH4AK4_2339	ENOG4105VRT	cytoplasmic protein
AH4AK4_2340	ENOG4105EIZ	Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity)
AH4AK4_2341	ENOG4105FD2	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) (By similarity)
AH4AK4_2344	ENOG4106EG9	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) (By similarity)
AH4AK4_2345	ENOG4105CFV	Tetratricopeptide repeat protein
AH4AK4_2347	ENOG41080YA	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
AH4AK4_2348	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
AH4AK4_2349	ENOG4105CAT	Cytidine monophosphate kinase
AH4AK4_2350	ENOG4108JEN	Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate (By similarity)
AH4AK4_2351	ENOG4105DUM	transcriptional regulator, lysR family
AH4AK4_2352	ENOG4105D2S	major facilitator superfamily
AH4AK4_2355	ENOG4108DBC	nitroreductase
AH4AK4_2356	ENOG4105CFC	Transporter
AH4AK4_2357	ENOG4105BZU	Histidine kinase
AH4AK4_2359	ENOG4105CBN	LysR family transcriptional regulator
AH4AK4_2360	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
AH4AK4_2365	ENOG4107RGM	aldo keto reductase
AH4AK4_2366	ENOG4105VFU	Rna-binding protein
AH4AK4_2368	ENOG4105HPZ	Involved in the removal of murein from the sacculus. May also facilitate integration of nascent murein strands into the sacculus by cleaving the peptide bonds between neighboring strands in mature murein (By similarity)
AH4AK4_2371	ENOG4105HA9	of methanol dehydrogenase type
AH4AK4_2374	ENOG4105E14	MotA TolQ exbB proton channel
AH4AK4_2375	ENOG4105ER2	Ompa motb domain protein
AH4AK4_2376	ENOG4105KWU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
AH4AK4_2377	ENOG4105ES3	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
AH4AK4_2378	ENOG4105CQV	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
AH4AK4_2379	ENOG4105GKE	subunit e
AH4AK4_2380	ENOG4107QIZ	NADH dehydrogenase
AH4AK4_2381	ENOG4108IEH	NADH dehydrogenase subunit g
AH4AK4_2382	ENOG4105CMZ	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone (By similarity)
AH4AK4_2383	ENOG4105P3U	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
AH4AK4_2384	ENOG4107UFS	subunit j
AH4AK4_2385	ENOG41080EA	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
AH4AK4_2386	ENOG4105D65	subunit l
AH4AK4_2387	ENOG4105C8S	subunit m
AH4AK4_2388	ENOG4105CNR	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
AH4AK4_2390	ENOG4107QIK	phosphoribosylformylglycinamidine synthase
AH4AK4_2392	ENOG4105CHQ	Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella (By similarity)
AH4AK4_2394	ENOG4105VPD	cellular component movement
AH4AK4_2395	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
AH4AK4_2396	ENOG4105CNE	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
AH4AK4_2397	ENOG4105N21	Membrane
AH4AK4_2398	ENOG4105CUT	histidyl-tRNA synthetase
AH4AK4_2399	ENOG4105C4E	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (By similarity)
AH4AK4_2400	ENOG4105HSZ	Cytoskeletal protein that is involved in cell-shape control through regulation of the length of the long axis (By similarity)
AH4AK4_2402	ENOG4105C55	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
AH4AK4_2403	ENOG4108UGX	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity)
AH4AK4_2404	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
AH4AK4_2406	ENOG4108ZIT	Ferredoxin, 2FE-2S
AH4AK4_2407	ENOG4105C9I	Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB
AH4AK4_2408	ENOG4108SWN	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA (By similarity)
AH4AK4_2409	ENOG4108Z4V	iron-sulfur cluster assembly
AH4AK4_2410	ENOG4107XTC	May be involved in the formation or repair of Fe-S clusters present in iron-sulfur proteins
AH4AK4_2411	ENOG4105C3J	Cysteine desulfurase
AH4AK4_2412	ENOG4108ZF1	Transcriptional regulator, BadM Rrf2 family
AH4AK4_2413	ENOG4105CVS	RNA methyltransferase TrmH family, group 1
AH4AK4_2415	ENOG4105XPQ	lipid carrier protein
AH4AK4_2416	ENOG4105CFP	Peptidase U32
AH4AK4_2417	ENOG4106RZ4	Peptidase U32
AH4AK4_2419	ENOG4105M78	Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide (By similarity)
AH4AK4_2420	ENOG4107RAB	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
AH4AK4_2421	ENOG4107QN8	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
AH4AK4_2422	ENOG4105VIE	preprotein translocase, subunit YajC
AH4AK4_2423	ENOG4105C6U	Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity)
AH4AK4_2424	ENOG4105E2N	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) (By similarity)
AH4AK4_2425	ENOG4105W87	Cbs domain
AH4AK4_2426	ENOG4105D3R	alkyl hydroperoxide reductase
AH4AK4_2428	ENOG4108ISG	Major Facilitator
AH4AK4_2432	ENOG4105J0Q	Transcriptional regulator
AH4AK4_2433	ENOG410829K	Lysine exporter protein (Lyse ygga)
AH4AK4_2434	ENOG4105CCG	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is tranferred onto alpha-ketoisovalerate to form ketopantoate (By similarity)
AH4AK4_2435	ENOG4105CBI	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
AH4AK4_2437	ENOG4105KE9	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity)
AH4AK4_2438	ENOG4105D43	The glycine cleavage system catalyzes the degradation of glycine (By similarity)
AH4AK4_2439	ENOG4105EAK	ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family
AH4AK4_2440	ENOG4105D0A	hydroxylase
AH4AK4_2443	ENOG4105ETE	Transcriptional regulator (LacI family
AH4AK4_2444	ENOG4105C2J	ABC transporter
AH4AK4_2445	ENOG4105CNN	ABC, transporter
AH4AK4_2446	ENOG4105E9V	Periplasmic binding protein LacI transcriptional regulator
AH4AK4_2449	ENOG4105E5M	Multidrug resistance protein D
AH4AK4_2450	ENOG4105C3U	ABC transporter
AH4AK4_2451	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
AH4AK4_2452	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
AH4AK4_2454	ENOG4105CYM	Glutathione S-transferase
AH4AK4_2455	ENOG4108RXX	maleylacetoacetate isomerase
AH4AK4_2458	ENOG4105EIY	sodium-type flagellar protein motY
AH4AK4_2461	ENOG4105DH5	Responsible for the end-turnover of tRNA specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis (By similarity)
AH4AK4_2462	ENOG4105D3Y	Na H antiporter
AH4AK4_2464	ENOG4105EQ2	LysR family Transcriptional regulator
AH4AK4_2466	ENOG4105C1J	atp-dependent rna helicase
AH4AK4_2467	ENOG4105KA0	thioesterase Superfamily protein
AH4AK4_2469	ENOG4105CQB	FAD linked oxidase domain protein
AH4AK4_2472	ENOG4105EE5	Membrane protein terC
AH4AK4_2473	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
AH4AK4_2474	ENOG4105EKD	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism (By similarity)
AH4AK4_2475	ENOG4105D4U	had-superfamily hydrolase, subfamily iia
AH4AK4_2477	ENOG4105CAQ	asparagine synthetase
AH4AK4_2479	ENOG4108RXX	maleylacetoacetate isomerase
AH4AK4_2481	ENOG4105F1J	Homogentisate 1,2-dioxygenase
AH4AK4_2482	ENOG4105E6K	4-Hydroxyphenylpyruvate dioxygenase
AH4AK4_2484	ENOG4108W1A	pseudouridine synthase
AH4AK4_2485	ENOG4105BZU	Histidine kinase
AH4AK4_2486	ENOG4107RHT	methyl-accepting chemotaxis sensory transducer with Pas Pac sensor
AH4AK4_2487	ENOG4105CEY	Amp-dependent synthetase and ligase
AH4AK4_2489	ENOG4108MIW	Induces the synthesis of acid phosphatase (AppA) and several other polypeptides (such as AppBC) during the deceleration phase of growth. It also acts as a transcriptional repressor for one group of proteins that are synthesized preferentially in exponential growth and for one group synthesized only in the stationary phase. Also involved in the stabilization of the sigma stress factor RpoS during stress conditions
AH4AK4_2492	ENOG4105D25	secreted protein
AH4AK4_2496	ENOG4105HMI	Membrane
AH4AK4_2498	ENOG4108J8C	transporter major facilitator family protein
AH4AK4_2500	ENOG4105E2B	Taurine dioxygenase
AH4AK4_2501	ENOG4105EE6	Alcohol dehydrogenase zinc-binding domain protein
AH4AK4_2502	ENOG4105CR4	methylisocitrate lyase
AH4AK4_2503	ENOG4105BZN	citrate synthase
AH4AK4_2504	ENOG4108I0Z	Aconitate hydratase
AH4AK4_2505	ENOG4105C7F	AcnD-accessory protein PrpF
AH4AK4_2507	ENOG4107VGF	ig domain protein group 2 domain protein
AH4AK4_2510	ENOG4105CW0	outer membrane usher protein
AH4AK4_2512	ENOG4108WDE	Fimbrial protein
AH4AK4_2514	ENOG4108MN8	Membrane
AH4AK4_2515	ENOG4105EM2	membrane
AH4AK4_2516	ENOG4108Z0T	Part of a sulfur-relay system (By similarity)
AH4AK4_2517	ENOG4108S3P	Sporulation domain protein
AH4AK4_2518	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
AH4AK4_2519	ENOG4107QTG	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA (By similarity)
AH4AK4_2520	ENOG4105DI7	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity)
AH4AK4_2523	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
AH4AK4_2524	ENOG4105CJ0	Catalyzes the oxidation of erythronate-4-phosphate to 3- hydroxy-2-oxo-4-phosphonooxybutanoate (By similarity)
AH4AK4_2525	ENOG4105YVM	Phosphoesterase, PA-phosphatase related
AH4AK4_2526	ENOG4105D01	(LipO)protein
AH4AK4_2529	ENOG4105DKW	ABC transporter
AH4AK4_2533	ENOG4108HRN	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate (By similarity)
AH4AK4_2534	ENOG4105CF9	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation (By similarity)
AH4AK4_2536	ENOG4105C85	amino acid
AH4AK4_2543	ENOG4105C42	Type I secretion membrane fusion protein (HlyD
AH4AK4_2545	ENOG4105N5T	Radical SAM Protein
AH4AK4_2546	ENOG4105CBC	glutamate synthase
AH4AK4_2547	ENOG4105BZ8	glutamate synthase
AH4AK4_2548	ENOG4105CDA	abc transporter atp-binding protein
AH4AK4_2549	ENOG4105DRP	amino acid AbC transporter
AH4AK4_2550	ENOG4105EAB	amino acid AbC transporter
AH4AK4_2551	ENOG4108Z4X	TRANSCRIPTIONal
AH4AK4_2556	ENOG4105C1J	atp-dependent rna helicase
AH4AK4_2560	ENOG4107QS8	(LipO)protein
AH4AK4_2561	ENOG4106TD9	Diguanylate cyclase
AH4AK4_2562	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
AH4AK4_2564	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
AH4AK4_2565	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
AH4AK4_2566	ENOG4105DUK	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity)
AH4AK4_2568	ENOG4105MK2	5-formyltetrahydrofolate cyclo-ligase
AH4AK4_2569	ENOG4105E66	phosphoriboisomerase A
AH4AK4_2571	ENOG4108JQ1	Dehydrogenase
AH4AK4_2572	ENOG41080IJ	Diacylglycerol kinase
AH4AK4_2573	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
AH4AK4_2574	ENOG41080WI	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system (By similarity)
AH4AK4_2575	ENOG4108ESU	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Involved in the translocation of the substrate across the membrane (By similarity)
AH4AK4_2578	ENOG4105CZX	twitching motility protein
AH4AK4_2579	ENOG4107QQ4	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans (By similarity)
AH4AK4_2583	ENOG4108ZJT	translation initiation factor, Sui1
AH4AK4_2591	ENOG410620I	Diguanylate cyclase
AH4AK4_2595	ENOG4105C8N	cysteinyl-tRNA synthetase
AH4AK4_2596	ENOG4108R5K	PPIases accelerate the folding of proteins (By similarity)
AH4AK4_2598	ENOG4105F10	Catalyzes the hydrolysis of the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1- phosphate (lipid X) and UMP (By similarity)
AH4AK4_2599	ENOG4105Y3U	Transglycosylase-associated protein
AH4AK4_2600	ENOG4108TGY	Glutathione S-transferase
AH4AK4_2602	ENOG4107EXU	Short-chain dehydrogenase reductase Sdr
AH4AK4_2603	ENOG4105EQ2	LysR family Transcriptional regulator
AH4AK4_2605	ENOG4108IYS	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
AH4AK4_2620	ENOG4105KT5	UmuD protein
AH4AK4_2624	ENOG4105ED4	portal protein
AH4AK4_2639	ENOG4106050	phage regulatory protein, rha family
AH4AK4_2646	ENOG410685N	tail fiber protein
AH4AK4_2661	ENOG4105CII	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity)
AH4AK4_2663	ENOG4105WH1	Two component transcriptional regulator luxr family
AH4AK4_2664	ENOG4105CET	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria (By similarity)
AH4AK4_2665	ENOG4105W49	UPF0434 protein
AH4AK4_2666	ENOG4105CHD	Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) (By similarity)
AH4AK4_2667	ENOG4105BZ1	(ABC) transporter
AH4AK4_2668	ENOG4108EQH	DNA internalization-related competence protein ComEC Rec2
AH4AK4_2671	ENOG4105D7A	ATP-binding protein
AH4AK4_2672	ENOG4105CGF	Aromatic amino acid aminotransferase
AH4AK4_2674	ENOG4105QMY	Porin Gram-negative type
AH4AK4_2675	ENOG4105DVT	helicase
AH4AK4_2677	ENOG4105DGU	Histone deacetylase
AH4AK4_2678	ENOG4108ISG	Major Facilitator
AH4AK4_2679	ENOG4105C9W	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity (By similarity)
AH4AK4_2680	ENOG4105G6Z	alkaline phosphatase
AH4AK4_2684	ENOG4105NXH	GreA GreB family elongation factor
AH4AK4_2685	ENOG4108KX4	response regulator
AH4AK4_2686	ENOG4105BZU	Histidine kinase
AH4AK4_2687	ENOG4105CXY	transporter
AH4AK4_2689	ENOG4106PMH	Extracellular solute-binding protein family 3
AH4AK4_2690	ENOG4105E5Q	amino acid AbC transporter
AH4AK4_2693	ENOG4105CDA	abc transporter atp-binding protein
AH4AK4_2696	ENOG4105D5Q	Arginine ornithine antiporter
AH4AK4_2699	ENOG4105C37	(CBS) domain
AH4AK4_2700	ENOG4108UTW	Plays a role in the regulation of phosphate uptake
AH4AK4_2701	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
AH4AK4_2702	ENOG4105E2Z	phosphate ABC transporter (Permease
AH4AK4_2703	ENOG4105C8U	phosphate abc transporter
AH4AK4_2704	ENOG4108Z6B	deaminase
AH4AK4_2707	ENOG4107QP3	malate synthase g
AH4AK4_2708	ENOG4108I9X	Isocitrate lyase
AH4AK4_2711	ENOG4105CZ5	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate (By similarity)
AH4AK4_2712	ENOG4105CXB	phosphoribosylaminoimidazole synthetase
AH4AK4_2713	ENOG4108V3E	phosphoribosylglycinamide formyltransferase
AH4AK4_2714	ENOG4107QNR	UPF0135 protein
AH4AK4_2716	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
AH4AK4_2717	ENOG4105BZU	Histidine kinase
AH4AK4_2718	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
AH4AK4_2721	ENOG4105RH4	Glycine cleavage system transcriptional repressor
AH4AK4_2722	ENOG4105CUU	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) (By similarity)
AH4AK4_2723	ENOG4105C9X	ppx gppa phosphatase
AH4AK4_2724	ENOG4105CJW	magnesium transporter
AH4AK4_2727	ENOG4108ZW7	flagellar rod assembly protein muramidase flgj
AH4AK4_2728	ENOG4105D92	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity)
AH4AK4_2729	ENOG4107W7W	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity)
AH4AK4_2730	ENOG4105CGA	flagellar basal-body rod protein FlgG
AH4AK4_2731	ENOG4108KPB	Flagellar basal-body rod protein FlgF
AH4AK4_2732	ENOG4105BZE	flagellar hook protein, FlgE
AH4AK4_2734	ENOG4108ZC9	flagellar basal-body rod protein flgc
AH4AK4_2735	ENOG4105K88	Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body (By similarity)
AH4AK4_2736	ENOG4105BZU	Histidine kinase
AH4AK4_2737	ENOG4107R88	Chemotaxis protein (CheV)
AH4AK4_2738	ENOG4107ESN	Flagella basal body P-ring formation protein flgA
AH4AK4_2741	ENOG4108RE9	Phosphodiesterase
AH4AK4_2742	ENOG4107QSI	ABC, transporter
AH4AK4_2744	ENOG4105I08	Pseudouridine synthase
AH4AK4_2745	ENOG4105CPI	Metal Dependent Phosphohydrolase
AH4AK4_2747	ENOG4108594	Permease of the drug metabolite transporter
AH4AK4_2753	ENOG4105VEQ	Cold shock protein
AH4AK4_2754	ENOG4107QSN	dihydrolipoamide acetyltransferase
AH4AK4_2755	ENOG4105CPP	Dehydrogenase, E1 component
AH4AK4_2756	ENOG4107RUY	(E1 component), alpha subunit
AH4AK4_2760	ENOG4105KR1	Trans-acting protein required for termination of DNA replication. Binds to DNA replication terminator sequences (terA to terF) to prevent the passage of replication forks. The termination efficiency will be affected by the affinity of this protein for the terminator sequence (By similarity)
AH4AK4_2762	ENOG4108YXG	UPF0502 protein
AH4AK4_2765	ENOG4108KPN	Confers a modal distribution of chain length on the O- antigen component of lipopolysaccharide (LPS). Gives rise to a reduced number of short chain molecules and increases in numbers of longer molecules, with a modal value of 13 (in strain O111 M92) and of 17 (in strain K12)
AH4AK4_2767	ENOG4108URP	Dtdp-4-dehydrorhamnose 3,5-epimerase
AH4AK4_2768	ENOG4108I19	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis (By similarity)
AH4AK4_2769	ENOG4105DBZ	Dtdp-4-dehydrorhamnose reductase
AH4AK4_2772	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
AH4AK4_2776	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
AH4AK4_2778	ENOG4108I19	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis (By similarity)
AH4AK4_2779	ENOG4105C1B	dTDP-glucose 4-6-dehydratase
AH4AK4_2781	ENOG4105IFJ	Histidine kinase
AH4AK4_2783	ENOG4105CHC	glucokinase (EC 2.7.1.2)
AH4AK4_2784	ENOG4106KNT	transcriptional regulator
AH4AK4_2785	ENOG4105CA9	Pyruvate kinase
AH4AK4_2787	ENOG4105BZS	acriflavin resistance protein
AH4AK4_2788	ENOG4107QPN	acyl-Coa dehydrogenase
AH4AK4_2790	ENOG4107SSZ	Phosphatase
AH4AK4_2801	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
AH4AK4_2814	ENOG4108YGG	dna repair protein
AH4AK4_2817	ENOG4105DE7	Sulfate ABC transporter periplasmic sulfate-binding protein
AH4AK4_2818	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
AH4AK4_2819	ENOG4105BZS	acriflavin resistance protein
AH4AK4_2820	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
AH4AK4_2821	ENOG4108IG5	Transcriptional regulator
AH4AK4_2824	ENOG4105C29	acyl-CoA thioesterase
AH4AK4_2825	ENOG4105FE9	pseudouridine synthase
AH4AK4_2826	ENOG4105K8I	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves (By similarity)
AH4AK4_2828	ENOG4107RTD	sua5 ycio yrdc ywlc family protein
AH4AK4_2829	ENOG4105DB7	PHP domain protein
AH4AK4_2831	ENOG4105CRQ	synthase (Component I)
AH4AK4_2832	ENOG4108EFP	Anthranilate synthase component II
AH4AK4_2833	ENOG4108I0Q	anthranilate phosphoribosyltransferase
AH4AK4_2834	ENOG4105DK0	Indole-3-glycerol phosphate synthase
AH4AK4_2835	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
AH4AK4_2836	ENOG4105F6H	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate (By similarity)
AH4AK4_2839	ENOG4105S2T	inner membrane protein YbcI
AH4AK4_2843	ENOG4105CC0	LysR family Transcriptional regulator
AH4AK4_2845	ENOG4106FTQ	Taurine ABC transporter, periplasmic
AH4AK4_2846	ENOG4108ETV	ABC transporter
AH4AK4_2847	ENOG4105EUS	Binding-protein-dependent transport systems, inner membrane component
AH4AK4_2848	ENOG4105EUS	Binding-protein-dependent transport systems, inner membrane component
AH4AK4_2849	ENOG4105EUS	Binding-protein-dependent transport systems, inner membrane component
AH4AK4_2850	ENOG4105E2B	Taurine dioxygenase
AH4AK4_2851	ENOG4105KCV	RNA signal recognition particle 4.5S RNA
AH4AK4_2852	ENOG4107RDB	Major Facilitator
AH4AK4_2853	ENOG4105F1R	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group (By similarity)
AH4AK4_2854	ENOG41090KH	cytochrome o ubiquinol oxidase (subunit iv)
AH4AK4_2855	ENOG4105CCU	oxidase (Subunit III)
AH4AK4_2856	ENOG4105BZ9	Cytochrome C oxidase, subunit I
AH4AK4_2857	ENOG4105E2S	oxidase) subunit II
AH4AK4_2858	ENOG4105MDH	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity (By similarity)
AH4AK4_2859	ENOG4105CC0	LysR family Transcriptional regulator
AH4AK4_2869	ENOG4105CGK	Exodeoxyribonuclease III
AH4AK4_2871	ENOG4105EP1	Efflux transporter rnd family, mfp subunit
AH4AK4_2872	ENOG4108IJF	Heavy metal efflux pump, CzcA
AH4AK4_2875	ENOG4107RMF	Catalyzes both the ATP-dependent activation of exogenously supplied lipoate to lipoyl-AMP and the transfer of the activated lipoyl onto the lipoyl domains of lipoate-dependent enzymes (By similarity)
AH4AK4_2876	ENOG4105BZU	Histidine kinase
AH4AK4_2877	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
AH4AK4_2878	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
AH4AK4_2879	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
AH4AK4_2883	ENOG41080HT	Transcriptional regulator, arsr family
AH4AK4_2886	ENOG4105WBN	Transcriptional regulator (LacI family
AH4AK4_2889	ENOG4105D7K	pfkb domain protein
AH4AK4_2891	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
AH4AK4_2892	ENOG4105CFG	Acts as a chaperone (By similarity)
AH4AK4_2893	ENOG4105K90	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
AH4AK4_2894	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
AH4AK4_2895	ENOG4105BZU	Histidine kinase
AH4AK4_2896	ENOG4105C4F	May be involved in recombinational repair of damaged DNA (By similarity)
AH4AK4_2897	ENOG4105E2M	Manganese-dependent inorganic pyrophosphatase
AH4AK4_2899	ENOG4105DJY	efflux transporter, rnd family, mfp subunit
AH4AK4_2900	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
AH4AK4_2901	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
AH4AK4_2902	ENOG4105Q26	Siderophore-interacting protein
AH4AK4_2906	ENOG4105W8I	Transcriptional regulator
AH4AK4_2908	ENOG4105BZC	d-serine deaminase
AH4AK4_2911	ENOG4108HMX	isocitrate dehydrogenase (NADP)
AH4AK4_2912	ENOG4106R3P	AraC family transcriptional regulator
AH4AK4_2913	ENOG4105EIP	mannose-6-phosphate isomerase
AH4AK4_2914	ENOG4105P66	Membrane
AH4AK4_2916	ENOG4105DM4	PTS System
AH4AK4_2919	ENOG4107VGF	ig domain protein group 2 domain protein
AH4AK4_2921	ENOG4105DM4	PTS System
AH4AK4_2922	ENOG4105CXY	transporter
AH4AK4_2924	ENOG4108YRF	PTS System
AH4AK4_2926	ENOG4108R99	pseudouridine synthase
AH4AK4_2928	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
AH4AK4_2929	ENOG41075W9	High frequency lysogenization protein HflD homolog
AH4AK4_2930	ENOG4107QTF	adenylosuccinate lyase
AH4AK4_2931	ENOG4105EZE	Cupin 4 family protein
AH4AK4_2932	ENOG4105CA9	Pyruvate kinase
AH4AK4_2933	ENOG4105EGS	Mechanosensitive ion channel
AH4AK4_2935	ENOG4105HHQ	6-phosphogluconolactonase (EC 3.1.1.31)
AH4AK4_2938	ENOG4105C2W	permease
AH4AK4_2940	ENOG4107R1I	NAD-dependent malic enzyme
AH4AK4_2941	ENOG4105C6R	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor (By similarity)
AH4AK4_2942	ENOG4105FNP	Molybdopterin-guanine dinucleotide biosynthesis protein b
AH4AK4_2943	ENOG4105DR8	Membrane
AH4AK4_2944	ENOG4108ESY	Metal dependent phosphohydrolase
AH4AK4_2947	ENOG4107SDU	Methyl-accepting chemotaxis
AH4AK4_2957	ENOG4105I4A	GCN5-related N-acetyltransferase
AH4AK4_2960	ENOG4108VSZ	Inherit from COG: ketosteroid isomerase-like protein
AH4AK4_2961	ENOG4105D98	threonine synthase
AH4AK4_2962	ENOG4105D5I	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate (By similarity)
AH4AK4_2964	ENOG4106FVC	RNA methyltransferase
AH4AK4_2965	ENOG4105VS7	Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue. This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon. When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation (By similarity)
AH4AK4_2968	ENOG4108YYX	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. Modulates RNA-binding and helicase activities of the degradosome (By similarity)
AH4AK4_2970	ENOG41065U4	response regulator
AH4AK4_2973	ENOG4108JJ9	ABC, transporter
AH4AK4_2974	ENOG4108JJ8	(ABC) transporter
AH4AK4_2978	ENOG4108R96	Methyltransferase, YaeB family
AH4AK4_2982	ENOG4105C6T	cysteine synthase
AH4AK4_2983	ENOG4105KZ7	phosphocarrier protein hpr
AH4AK4_2985	ENOG4105C5Y	PTS System
AH4AK4_2986	ENOG4108VKM	cytochrome b561
AH4AK4_2987	ENOG4105EYH	Exonuclease
AH4AK4_2988	ENOG4107RH8	nuclease SbcCD subunit D
AH4AK4_2989	ENOG4105K5X	acetyltransferase
AH4AK4_2990	ENOG4105DH7	May be involved in recombination (By similarity)
AH4AK4_2991	ENOG4108UJV	acyl-CoA thioesterase i
AH4AK4_2992	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
AH4AK4_2993	ENOG4105CKD	glutathione-regulated potassium-efflux system protein
AH4AK4_3000	ENOG4105CJP	fad dependent oxidoreductase
AH4AK4_3001	ENOG4107VRI	Transcriptional regulator
AH4AK4_3002	ENOG4105C26	Dehydrogenase
AH4AK4_3003	ENOG4108JPW	Aminotransferase
AH4AK4_3004	ENOG4105CUB	amino acid
AH4AK4_3005	ENOG4105CUB	amino acid
AH4AK4_3008	ENOG4108V1T	peptidylprolyl cis-trans isomerase
AH4AK4_3009	ENOG4105C8E	extradiol ring-cleavage dioxygenase class IIi protein subunit b
AH4AK4_3010	ENOG4105BZU	Histidine kinase
AH4AK4_3012	ENOG4105XIQ	Protein of unknown function (DUF2517)
AH4AK4_3016	ENOG4105BZU	Histidine kinase
AH4AK4_3017	ENOG4105EQ2	LysR family Transcriptional regulator
AH4AK4_3018	ENOG4105ENX	hydrolase
AH4AK4_3020	ENOG4107RTG	Major Facilitator superfamily
AH4AK4_3022	ENOG4105DFH	Transport of potassium into the cell (By similarity)
AH4AK4_3025	ENOG4107N1Q	ErfK YbiS YcfS YnhG family protein
AH4AK4_3028	ENOG4105EBA	Specifically methylates the adenine in position 1618 of 23S rRNA (By similarity)
AH4AK4_3029	ENOG4107TT5	NLP P60 protein
AH4AK4_3030	ENOG4107YAK	holo-(acyl carrier protein) synthase 2
AH4AK4_3031	ENOG4107QR8	Thioredoxin
AH4AK4_3033	ENOG4105C66	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity)
AH4AK4_3035	ENOG4105CIY	formyltetrahydrofolate deformylase
AH4AK4_3040	ENOG4105E4C	Lytic transglycosylase catalytic
AH4AK4_3042	ENOG4105D8C	Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity)
AH4AK4_3043	ENOG4105NHU	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group (By similarity)
AH4AK4_3044	ENOG4105EP9	oxidoreductase
AH4AK4_3049	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
AH4AK4_3050	ENOG4105CCT	upf0313 protein
AH4AK4_3052	ENOG4105BZS	acriflavin resistance protein
AH4AK4_3054	ENOG4106TD9	Diguanylate cyclase
AH4AK4_3055	ENOG4105D78	K07001 NTE family protein
AH4AK4_3056	ENOG4105C8J	)-transporter
AH4AK4_3059	ENOG4105UYK	outer membrane protein a
AH4AK4_3062	ENOG4105UYK	outer membrane protein a
AH4AK4_3063	ENOG4107R1I	NAD-dependent malic enzyme
AH4AK4_3064	ENOG41075H3	AraC family transcriptional regulator
AH4AK4_3065	ENOG4105UQX	Mate efflux family protein
AH4AK4_3067	ENOG4105RKX	Protein of unknown function (DUF2498)
AH4AK4_3068	ENOG4105BZU	Histidine kinase
AH4AK4_3070	ENOG4105C2W	permease
AH4AK4_3071	ENOG4108KMH	lipoate-protein ligase a
AH4AK4_3072	ENOG4105BZG	amino acid carrier protein
AH4AK4_3076	ENOG4105PTV	Nudix Hydrolase
AH4AK4_3078	ENOG4105CDA	abc transporter atp-binding protein
AH4AK4_3079	ENOG4105DRP	amino acid AbC transporter
AH4AK4_3080	ENOG4105EZ7	amino acid ABC transporter
AH4AK4_3085	ENOG4105CJ1	ABC, transporter
AH4AK4_3086	ENOG4108V1T	peptidylprolyl cis-trans isomerase
AH4AK4_3087	ENOG4106N3A	copper homeostasis protein cutc
AH4AK4_3088	ENOG4105EZX	Catalyzes the phosphorylation of N-acetyl-D-glucosamine (GlcNAc) derived from cell-wall degradation, yielding GlcNAc-6-P (By similarity)
AH4AK4_3090	ENOG4105ERG	peptidase m48, ste24p
AH4AK4_3092	ENOG4105BZU	Histidine kinase
AH4AK4_3093	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
AH4AK4_3094	ENOG4108ZI4	Glyoxalase Bleomycin resistance protein (Dioxygenase
AH4AK4_3095	ENOG4105BZU	Histidine kinase
AH4AK4_3096	ENOG4108JU9	GAF modulated sigma54 specific transcriptional regulator Fis family
AH4AK4_3098	ENOG4105C26	Dehydrogenase
AH4AK4_3100	ENOG4108IPJ	Membrane
AH4AK4_3101	ENOG4106YYS	transcriptional regulatory protein
AH4AK4_3102	ENOG4105CEQ	signal transduction histidine kinase regulating citrate malate metabolism
AH4AK4_3103	ENOG4107R1I	NAD-dependent malic enzyme
AH4AK4_3106	ENOG4108US0	Transcription regulator that can specifically activate or repress expression of target genes (By similarity)
AH4AK4_3107	ENOG4105J12	Multidrug resistance protein mdtN
AH4AK4_3112	ENOG4108RDD	Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine (By similarity)
AH4AK4_3113	ENOG4105CJD	(Anaerobic) ribonucleoside-triphosphate reductase
AH4AK4_3115	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
AH4AK4_3117	ENOG4105CDB	Required for chromosome condensation and partitioning (By similarity)
AH4AK4_3118	ENOG4105EXN	Sulfate transport protein CysZ
AH4AK4_3119	ENOG4105EN6	Membrane
AH4AK4_3121	ENOG4105EAQ	(twin-arginine translocation) pathway signal
AH4AK4_3122	ENOG4105DIT	ErfK YbiS YcfS YnhG family protein
AH4AK4_3128	ENOG4107T9C	Alpha amylase catalytic region
AH4AK4_3135	ENOG4105BZU	Histidine kinase
AH4AK4_3136	ENOG4105D3U	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
AH4AK4_3137	ENOG4105C9K	Endothelin-converting enzyme 1
AH4AK4_3139	ENOG4105C5H	ABC transporter
AH4AK4_3141	ENOG4105DVH	amino acid
AH4AK4_3142	ENOG4105C44	Serine transporter
AH4AK4_3143	ENOG410642W	LysR family Transcriptional regulator
AH4AK4_3145	ENOG4105E2V	Glycosyltransferase 36
AH4AK4_3148	ENOG4105K3G	Periplasmic Protein
AH4AK4_3149	ENOG4107QM9	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA (By similarity)
AH4AK4_3150	ENOG4105C0B	DNA polymerase III (alpha subunit)
AH4AK4_3151	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
AH4AK4_3152	ENOG4105D0V	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
AH4AK4_3153	ENOG4105DAF	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
AH4AK4_3154	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
AH4AK4_3155	ENOG4105D7M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
AH4AK4_3156	ENOG4108RFI	Molecular chaperone that interacts specifically with outer membrane proteins, thus maintaining the solubility of early folding intermediates during passage through the periplasm (By similarity)
AH4AK4_3158	ENOG4105DZP	Membrane-associated zinc metalloprotease
AH4AK4_3159	ENOG4105CEA	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity)
AH4AK4_3160	ENOG4105KNE	Phosphatidate cytidylyltransferase
AH4AK4_3161	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
AH4AK4_3162	ENOG4108VCV	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity)
AH4AK4_3163	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
AH4AK4_3165	ENOG4105CU7	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity)
AH4AK4_3166	ENOG4105CE9	30S ribosomal protein S2
AH4AK4_3167	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
AH4AK4_3168	ENOG4105E1P	Modifies, by uridylylation or deuridylylation the PII (GlnB) regulatory protein (By similarity)
AH4AK4_3169	ENOG4105DMJ	Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate (By similarity)
AH4AK4_3170	ENOG4108T8E	UPF0325 protein
AH4AK4_3171	ENOG4105CI1	PTS System
AH4AK4_3172	ENOG4107W52	maltose operon periplasmic protein
AH4AK4_3173	ENOG4108KDD	Involved in the transport of maltose and maltodextrins (By similarity)
AH4AK4_3174	ENOG4105QDK	Flavodoxin
AH4AK4_3175	ENOG4105DR9	pseudouridine synthase
AH4AK4_3176	ENOG4105WP7	tRNA pseudouridine synthase C
AH4AK4_3182	ENOG4105EXF	Zn-ribbon-containing, possibly nucleic-acid-binding protein
AH4AK4_3183	ENOG4108T6E	Interacts with the SecY protein in vivo. May bind preferentially to an uncomplexed state of SecY, thus functioning either as a chelating agent for excess SecY in the cell or as a regulatory factor that negatively controls the translocase function (By similarity)
AH4AK4_3184	ENOG4107R1K	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) (By similarity)
AH4AK4_3186	ENOG4105BZU	Histidine kinase
AH4AK4_3188	ENOG4105EWT	decarboxylase family
AH4AK4_3189	ENOG4105CIQ	May have a role in processing of nucleic acids. It is probably not an exonuclease
AH4AK4_3190	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
AH4AK4_3192	ENOG4105EZ6	Catalyzes the 2'-O-methylation at nucleotide C2498 in 23S rRNA (By similarity)
AH4AK4_3193	ENOG4105M08	Membrane
AH4AK4_3195	ENOG4105ETT	transcriptional Regulator, LysR family
AH4AK4_3196	ENOG4105C8Q	Methyl-accepting chemotaxis
AH4AK4_3197	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
AH4AK4_3200	ENOG4105CJ2	(LipO)protein
AH4AK4_3201	ENOG4105D26	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. The first step is catalyzed by NqrF, which accepts electrons from NADH and reduces ubiquinone-1 to ubisemiquinone by a one-electron transfer pathway (By similarity)
AH4AK4_3202	ENOG4108IUB	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
AH4AK4_3203	ENOG4105F5D	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
AH4AK4_3204	ENOG4106I92	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
AH4AK4_3205	ENOG4108J5C	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
AH4AK4_3206	ENOG4105DWQ	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
AH4AK4_3207	ENOG4105M85	Bola protein
AH4AK4_3208	ENOG4105D8J	Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle (By similarity)
AH4AK4_3210	ENOG4108R5K	PPIases accelerate the folding of proteins (By similarity)
AH4AK4_3212	ENOG4105EYM	Major Facilitator superfamily
AH4AK4_3213	ENOG4105DRB	nucleoside-specific channel-forming protein
AH4AK4_3214	ENOG4108VPT	UPF0234 protein
AH4AK4_3215	ENOG4108JZF	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity)
AH4AK4_3216	ENOG4107S0N	DJ-1 family
AH4AK4_3217	ENOG4105C7K	acetolactate synthase
AH4AK4_3223	ENOG4105CS6	Rhs element vgr protein
AH4AK4_3224	ENOG4108WC9	type VI secretion system effector, hcp1 family
AH4AK4_3225	ENOG4105VJY	transcriptional regulator
AH4AK4_3227	ENOG4105H3G	oxidoreductase
AH4AK4_3228	ENOG4105K89	arsenate reductase
AH4AK4_3229	ENOG4105D6J	arsenicaL-resistance protein
AH4AK4_3231	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
AH4AK4_3238	ENOG4105BZU	Histidine kinase
AH4AK4_3239	ENOG4105E3W	Two component transcriptional regulator (Winged helix family
AH4AK4_3240	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
AH4AK4_3241	ENOG4105BZS	acriflavin resistance protein
AH4AK4_3244	ENOG4105DRC	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity)
AH4AK4_3245	ENOG4105CMR	udp-glucose 4-epimerase
AH4AK4_3246	ENOG4105CJJ	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity)
AH4AK4_3247	ENOG4105EJ7	Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O (By similarity)
AH4AK4_3248	ENOG4108RMU	ferritin dps family protein
AH4AK4_3253	ENOG4105CV9	cyclopropane-fatty-acyl-phospholipid synthase
AH4AK4_3256	ENOG4107FW0	short-chain dehydrogenase reductase
AH4AK4_3258	ENOG4105CVP	deoxyribo-dipyrimidine photolyase
AH4AK4_3259	ENOG4108XDN	Transcriptional regulator
AH4AK4_3260	ENOG4107SEY	Conserved Protein
AH4AK4_3266	ENOG4105CQC	Prephenate dehydratase
AH4AK4_3274	ENOG4107RDJ	Sulfotransferase
AH4AK4_3278	ENOG4105D8V	Glucose sorbosone dehydrogenase
AH4AK4_3280	ENOG4105MVE	transcriptional regulator
AH4AK4_3282	ENOG4105G63	Type III effector Hrp-dependent
AH4AK4_3284	ENOG4105QG4	Catalyzes the reversible isomerization between hydroxypyruvate and 2-hydroxy-3-oxopropanoate (also termed tartronate semialdehyde) (By similarity)
AH4AK4_3285	ENOG4105EXW	epimerase dehydratase
AH4AK4_3286	ENOG4105C6Z	Gluconate
AH4AK4_3288	ENOG4105C8Q	Methyl-accepting chemotaxis
AH4AK4_3291	ENOG4105E1F	short-chain dehydrogenase reductase
AH4AK4_3296	ENOG4105CTD	carboxy-peptidase
AH4AK4_3300	ENOG4105XDF	Protein of unknown function (DUF1272)
AH4AK4_3302	ENOG4105CFP	Peptidase U32
AH4AK4_3304	ENOG4105N14	lysine exporter protein LysE YggA
AH4AK4_3306	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
AH4AK4_3311	ENOG4105BZU	Histidine kinase
AH4AK4_3312	ENOG41068CG	regulatoR
AH4AK4_3314	ENOG4108N3D	putative enzyme
AH4AK4_3317	ENOG4108NJZ	Sensory box GGDEF EAL domain protein
AH4AK4_3319	ENOG4105DB1	molybdopterin oxidoreductase
AH4AK4_3320	ENOG4106WHD	Tetrathionate reductase
AH4AK4_3321	ENOG4105QA4	4Fe-4S Ferredoxin, iron-sulfur binding domain protein
AH4AK4_3322	ENOG4105BZU	Histidine kinase
AH4AK4_3323	ENOG4108ZXC	Two component transcriptional regulator, luxr family
AH4AK4_3324	ENOG4105EQ6	Hydrolyzes dipeptides containing N-terminal aspartate residues. May play a role in allowing the cell to use peptide aspartate to spare carbon otherwise required for the synthesis of the aspartate family of amino acids (By similarity)
AH4AK4_3327	ENOG4105C26	Dehydrogenase
AH4AK4_3328	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
AH4AK4_3329	ENOG4105CDU	Replicative dna helicase
AH4AK4_3332	ENOG4105CGH	5'-nucleotidase
AH4AK4_3336	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
AH4AK4_3337	ENOG4108V1T	peptidylprolyl cis-trans isomerase
AH4AK4_3339	ENOG4105VRX	Protein slyX homolog
AH4AK4_3340	ENOG4108YZY	peptidylprolyl cis-trans isomerase
AH4AK4_3341	ENOG4105VKU	nucleicacid-binding protein
AH4AK4_3343	ENOG4107R88	Chemotaxis protein (CheV)
AH4AK4_3344	ENOG4105DNZ	Alpha Beta Hydrolase
AH4AK4_3346	ENOG4105YP7	UPF0270 protein
AH4AK4_3347	ENOG4105CJE	phosphoribulokinase (EC 2.7.1.19)
AH4AK4_3350	ENOG4108UKZ	OsmC family
AH4AK4_3351	ENOG4107RYR	Transcriptional regulator, Crp Fnr family
AH4AK4_3353	ENOG4108MA4	Peptidase M66
AH4AK4_3356	ENOG4105BZU	Histidine kinase
AH4AK4_3357	ENOG4105D8G	Major Facilitator superfamily
AH4AK4_3362	ENOG4105PYN	Pyridoxamine 5-phosphate oxidase-related
AH4AK4_3363	ENOG41090JE	Utilization Protein
AH4AK4_3365	ENOG4105EHG	Permease protein
AH4AK4_3369	ENOG4105C6Y	Udp-glucose 6-dehydrogenase
AH4AK4_3371	ENOG4105SA9	Catalyzes the transfer of the L-Ara4N moiety of the glycolipid undecaprenyl phosphate-alpha-L-Ara4N to lipid A. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides (By similarity)
AH4AK4_3373	ENOG4105CKK	Glycosyl transferase, family 2
AH4AK4_3375	ENOG4105E4C	Lytic transglycosylase catalytic
AH4AK4_3376	ENOG4105C5H	ABC transporter
AH4AK4_3378	ENOG4105C7N	Xanthine uracil vitamin C permease
AH4AK4_3379	ENOG41066UG	Regulatory DnaK co-chaperone. Direct interaction between DnaK and DjlA is needed for the induction of the wcaABCDE operon, involved in the synthesis of a colanic acid polysaccharide capsule, possibly through activation of the RcsB RcsC phosphotransfer signaling pathway. The colanic acid capsule may help the bacterium survive conditions outside the host (By similarity)
AH4AK4_3380	ENOG4108S0S	Nucleotidyl transferase
AH4AK4_3381	ENOG4105EHM	Aminoglycoside phosphotransferase
AH4AK4_3382	ENOG4105E7H	involved in the assembly of LPS in the outer leaflet of the outer membrane. Determines N-hexane tolerance and is involved in outer membrane permeability. Essential for envelope biogenesis (By similarity)
AH4AK4_3384	ENOG4105CEZ	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) (By similarity)
AH4AK4_3385	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
AH4AK4_3386	ENOG4105NWN	ApaG protein
AH4AK4_3387	ENOG4105DDT	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP (By similarity)
AH4AK4_3390	ENOG4105DEN	Luciferase family
AH4AK4_3391	ENOG4105DHT	Metal Dependent Phosphohydrolase
AH4AK4_3392	ENOG4105DWD	nucleoside recognition domain protein
AH4AK4_3393	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
AH4AK4_3394	ENOG4105K46	50S ribosomal protein l27
AH4AK4_3395	ENOG4105EAH	synthase
AH4AK4_3397	ENOG4105EPW	hflc protein
AH4AK4_3398	ENOG4107QJR	hflk protein
AH4AK4_3399	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
AH4AK4_3400	ENOG4105KW8	RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity)
AH4AK4_3401	ENOG4105DKX	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity)
AH4AK4_3402	ENOG4105DC6	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity)
AH4AK4_3403	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
AH4AK4_3404	ENOG4105K8N	protein family UPF0079, ATPase
AH4AK4_3405	ENOG4105DR1	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)
AH4AK4_3410	ENOG4108JEI	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity)
AH4AK4_3411	ENOG4108UMI	ABC transporter, permease
AH4AK4_3412	ENOG4105D01	(LipO)protein
AH4AK4_3413	ENOG4105MDZ	Transcriptional activator rfaH
AH4AK4_3414	ENOG4105C8Q	Methyl-accepting chemotaxis
AH4AK4_3415	ENOG4105BZU	Histidine kinase
AH4AK4_3416	ENOG4105BZU	Histidine kinase
AH4AK4_3418	ENOG4105C4Q	deoxyguanosinetriphosphate triphosphohydrolase-like protein
AH4AK4_3419	ENOG4105BZU	Histidine kinase
AH4AK4_3424	ENOG4105EXG	Transcriptional regulator
AH4AK4_3426	ENOG4107QWK	SAICAR synthetase
AH4AK4_3427	ENOG4107EG0	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
AH4AK4_3428	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
AH4AK4_3429	ENOG4105RH4	Glycine cleavage system transcriptional repressor
AH4AK4_3430	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
AH4AK4_3431	ENOG4105XWI	UPF0304 protein
AH4AK4_3433	ENOG4105C6H	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity)
AH4AK4_3434	ENOG4105C6K	Malic enzyme
AH4AK4_3435	ENOG4108ZP8	Acetolactate synthase small subunit
AH4AK4_3436	ENOG4105C7K	acetolactate synthase
AH4AK4_3438	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
AH4AK4_3439	ENOG4105YVM	Phosphoesterase, PA-phosphatase related
AH4AK4_3441	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
AH4AK4_3442	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
AH4AK4_3443	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
AH4AK4_3444	ENOG4105MQS	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
AH4AK4_3447	ENOG4105DP9	ABC transporter
AH4AK4_3448	ENOG4106SMU	thiamine transporter membrane protein
AH4AK4_3449	ENOG4107T0D	ABC, transporter
AH4AK4_3450	ENOG4108IAB	Phoh family
AH4AK4_3458	ENOG4108YX9	iron--sulfur cluster insertion protein erpA
AH4AK4_3460	ENOG4105CMQ	Chloride channel
AH4AK4_3462	ENOG4105CDM	Glutamate-1-semialdehyde aminotransferase
AH4AK4_3466	ENOG41076MN	Phosphoesterase, PA-phosphatase related
AH4AK4_3468	ENOG4105EGI	Transcriptional regulator
AH4AK4_3469	ENOG41090TI	Catalyzes the excretion of spermidine (By similarity)
AH4AK4_3470	ENOG4108ZBZ	Catalyzes the excretion of spermidine (By similarity)
AH4AK4_3471	ENOG4108YZK	glyoxalase bleomycin resistance protein dioxygenase
AH4AK4_3472	ENOG4105BZ4	penicillin-binding protein
AH4AK4_3473	ENOG4105CQ7	ATP-dependent helicase
AH4AK4_3475	ENOG4105PW4	Sugar fermentation stimulation protein homolog
AH4AK4_3476	ENOG4108V7X	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
AH4AK4_3477	ENOG4106F3G	Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon (By similarity)
AH4AK4_3479	ENOG4105DJ0	Poly(A) Polymerase
AH4AK4_3480	ENOG4105K8U	2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
AH4AK4_3481	ENOG4105CCG	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is tranferred onto alpha-ketoisovalerate to form ketopantoate (By similarity)
AH4AK4_3482	ENOG4108IAA	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate (By similarity)
AH4AK4_3484	ENOG4105E3A	(ABC) transporter
AH4AK4_3485	ENOG4105DA5	(ABC) transporter
AH4AK4_3486	ENOG4108UGV	hypoxanthine phosphoribosyltransferase
AH4AK4_3487	ENOG410630P	Transcriptional regulator
AH4AK4_3488	ENOG4108UMA	3-octaprenyl-4-hydroxybenzoate carboxy-lyase
AH4AK4_3489	ENOG4105DFU	Cell wall formation (By similarity)
AH4AK4_3490	ENOG4105F0N	pyrophosphate phospho-hydrolase
AH4AK4_3493	ENOG4108UUE	Transcriptional regulator
AH4AK4_3496	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
AH4AK4_3503	ENOG4108I67	Catalyzes the synthesis of activated sulfate (By similarity)
AH4AK4_3505	ENOG4105C3T	may be the GTPase, regulating ATP sulfurylase activity (By similarity)
AH4AK4_3506	ENOG4105C11	sulfate adenylyltransferase), subunit 2
AH4AK4_3507	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
AH4AK4_3508	ENOG4107QX8	SPFH domain, Band 7 family protein
AH4AK4_3509	ENOG4105G5H	Membrane
AH4AK4_3511	ENOG4105D9R	oxidoreductase
AH4AK4_3512	ENOG4105CNH	Multidrug resistance protein MdtL
AH4AK4_3513	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
AH4AK4_3514	ENOG4105CSA	Coproporphyrinogen iii oxidase
AH4AK4_3515	ENOG4105VCN	Rescues the ribosomes stalled at the 3' end of non-stop mRNAs. May induce hydrolysis of the ribosome-bound peptidyl-tRNA. This activity is crucial when the stalled ribosome can not be rescued by the SsrA(tmRNA)-SmpB quality control system
AH4AK4_3519	ENOG4105DC1	bifunctional purine biosynthesis protein purh
AH4AK4_3520	ENOG4105C12	Phosphoribosylglycinamide synthetase
AH4AK4_3526	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
AH4AK4_3527	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
AH4AK4_3528	ENOG4105KTH	gatB Yqey
AH4AK4_3529	ENOG4105VCC	30S ribosomal protein S21
AH4AK4_3530	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
AH4AK4_3532	ENOG4108K5P	(LipO)protein
AH4AK4_3533	ENOG4108UM1	dedA family
AH4AK4_3534	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
AH4AK4_3535	ENOG4105CV2	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates (By similarity)
AH4AK4_3536	ENOG4106NZV	Responsible for synthesis of pseudouridine from uracil- 13 in transfer RNAs (By similarity)
AH4AK4_3537	ENOG4108UH8	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (By similarity)
AH4AK4_3538	ENOG4105CE5	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) (By similarity)
AH4AK4_3539	ENOG4105XX3	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity)
AH4AK4_3540	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
AH4AK4_3541	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
AH4AK4_3542	ENOG4105DXN	mazG family
AH4AK4_3543	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
AH4AK4_3544	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
AH4AK4_3545	ENOG4105BZU	Histidine kinase
AH4AK4_3546	ENOG4108W15	Protein of unknown function (DUF1456)
AH4AK4_3547	ENOG4108VBV	N-Acetylmuramoyl-L-alanine amidase
AH4AK4_3548	ENOG4105CSZ	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate (By similarity)
AH4AK4_3549	ENOG41071DT	Involved in DNA repair and RecF pathway recombination (By similarity)
AH4AK4_3551	ENOG4108ZBM	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity)
AH4AK4_3552	ENOG4105C3F	Signal peptidase i
AH4AK4_3553	ENOG4105C4S	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity)
AH4AK4_3557	ENOG4105EMN	RNA polymerase sigma factor
AH4AK4_3558	ENOG4108IYU	L-aspartate oxidase
AH4AK4_3560	ENOG4105Y75	tpr repeat protein
AH4AK4_3566	ENOG4105CSG	Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps (By similarity)
AH4AK4_3568	ENOG4105CJP	fad dependent oxidoreductase
AH4AK4_3569	ENOG4105D2N	Aldolase
AH4AK4_3570	ENOG4105BZA	Phosphoglycerate kinase
AH4AK4_3571	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
AH4AK4_3572	ENOG4105DKQ	ROK family
AH4AK4_3573	ENOG4105CFZ	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III (By similarity)
AH4AK4_3574	ENOG4105E09	nadh pyrophosphatase
AH4AK4_3575	ENOG4106MWK	domain protein
AH4AK4_3576	ENOG4105EYW	Ion transport protein
AH4AK4_3577	ENOG4105C8Q	Methyl-accepting chemotaxis
AH4AK4_3579	ENOG4105CE6	Adenylation and deadenylation of glutamate--ammonia ligase (By similarity)
AH4AK4_3580	ENOG4105CYX	Short-chain dehydrogenase reductase Sdr
AH4AK4_3583	ENOG4108IYI	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine (By similarity)
AH4AK4_3584	ENOG4105E5Q	amino acid AbC transporter
AH4AK4_3585	ENOG4105E5Q	amino acid AbC transporter
AH4AK4_3586	ENOG4105CDA	abc transporter atp-binding protein
AH4AK4_3587	ENOG4105CT1	(ABC) transporter
AH4AK4_3588	ENOG4107PU6	Membrane
AH4AK4_3589	ENOG4108UW5	maltose o-acetyltransferase
AH4AK4_3593	ENOG4107VGF	ig domain protein group 2 domain protein
AH4AK4_3599	ENOG41090U3	tautomerase
AH4AK4_3601	ENOG4107NQ8	LysR family Transcriptional regulator
AH4AK4_3602	ENOG4105CH7	arginosuccinase
AH4AK4_3603	ENOG4105CDH	Citrulline--aspartate ligase
AH4AK4_3605	ENOG4105CAS	nag kinase
AH4AK4_3606	ENOG4105C0N	N-acetylglutamate semialdehyde dehydrogenase
AH4AK4_3608	ENOG4105CCA	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle (By similarity)
AH4AK4_3610	ENOG4105BZU	Histidine kinase
AH4AK4_3611	ENOG4108Z66	YbaK ebsC protein
AH4AK4_3617	ENOG4105CMU	LysR family (Transcriptional regulator
AH4AK4_3619	ENOG41067MG	lrgb family
AH4AK4_3620	ENOG4105CFH	Aspartokinase
AH4AK4_3621	ENOG4105C28	cystathionine
AH4AK4_3622	ENOG4105GGQ	This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis (By similarity)
AH4AK4_3624	ENOG4108Z7R	Chaperone CsaA
AH4AK4_3625	ENOG4105C44	Serine transporter
AH4AK4_3626	ENOG4108RNI	3'(2')5'-bisphosphate nucleotidase
AH4AK4_3627	ENOG4107RK2	ADP-ribose diphosphatase NudE
AH4AK4_3628	ENOG4107Y3D	HAD-superfamily hydrolase subfamily IA variant 3
AH4AK4_3630	ENOG4105JQN	Transcriptional regulator
AH4AK4_3631	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
AH4AK4_3632	ENOG4108UDW	Transcriptional regulator, luxr family
AH4AK4_3640	ENOG4108VAU	general secretion pathway protein G
AH4AK4_3641	ENOG4105D7Q	type ii secretion system
AH4AK4_3642	ENOG4107QHF	type ii secretion system protein e
AH4AK4_3643	ENOG4105GVR	general secretion pathway protein D
AH4AK4_3645	ENOG4105VEJ	Heat shock protein
AH4AK4_3646	ENOG4105F4C	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress (By similarity)
AH4AK4_3647	ENOG4105DJ1	Phosphoenolpyruvate Carboxylase
AH4AK4_3651	ENOG4108XTF	Outer Membrane Lipoprotein
AH4AK4_3652	ENOG4105I7R	Adenylate cyclase
AH4AK4_3653	ENOG4107IX6	phosphate transport regulator
AH4AK4_3654	ENOG4105CJ3	phosphate transporter
AH4AK4_3655	ENOG4105D4J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
AH4AK4_3658	ENOG4105CEN	a g-specific adenine glycosylase
AH4AK4_3659	ENOG4105KMG	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes (By similarity)
AH4AK4_3665	ENOG4108Q2G	(LipO)protein
AH4AK4_3666	ENOG4105DY2	Paraquat-inducible protein b
AH4AK4_3667	ENOG4105F1S	paraquat-inducible protein a
AH4AK4_3669	ENOG4105KW8	RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity)
AH4AK4_3670	ENOG4107VXZ	Hydrolase
AH4AK4_3672	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
AH4AK4_3673	ENOG4105D8J	Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle (By similarity)
AH4AK4_3674	ENOG4107QQ4	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans (By similarity)
AH4AK4_3675	ENOG4105CXW	Synthesizes alpha-1,4-glucan chains using ADP-glucose (By similarity)
AH4AK4_3682	ENOG4105DFD	Na H antiporter
AH4AK4_3683	ENOG4108M0I	Transcriptional regulator
AH4AK4_3684	ENOG4107TYH	extracellular solute-binding protein family 1
AH4AK4_3685	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
AH4AK4_3686	ENOG4105D81	ABC transporter, permease
AH4AK4_3687	ENOG4105NRK	Binding-protein-dependent transport systems, inner membrane component
AH4AK4_3688	ENOG4105C26	Dehydrogenase
AH4AK4_3689	ENOG4105F1R	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group (By similarity)
AH4AK4_3694	ENOG4107QS1	Cytochrome C Oxidase, Subunit III
AH4AK4_3696	ENOG4105FT1	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I (By similarity)
AH4AK4_3699	ENOG4105E0I	Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of tRNA(Met), by using acetyl-CoA as an acetyl donor and ATP (or GTP) (By similarity)
AH4AK4_3702	ENOG4108UQY	Iron-storage protein
AH4AK4_3703	ENOG4108Z5K	methylglyoxal synthase
AH4AK4_3706	ENOG4105HDK	L-asparaginase
AH4AK4_3708	ENOG4105ETE	Transcriptional regulator (LacI family
AH4AK4_3711	ENOG4105DKQ	ROK family
AH4AK4_3712	ENOG4105VCP	PTS System
AH4AK4_3713	ENOG4105CS2	ec 3.2.1.21
AH4AK4_3714	ENOG4105CK1	PTS System
AH4AK4_3716	ENOG4105CK1	PTS System
AH4AK4_3718	ENOG4105D4X	repressor
AH4AK4_3719	ENOG4105C5Y	PTS System
AH4AK4_3720	ENOG4105CG3	alpha amylase, catalytic region
AH4AK4_3721	ENOG4108UW5	maltose o-acetyltransferase
AH4AK4_3728	ENOG4105UYK	outer membrane protein a
AH4AK4_3733	ENOG4105K7Z	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP (By similarity)
AH4AK4_3734	ENOG4107ZVW	dihydroneopterin aldolase
AH4AK4_3735	ENOG4105K8U	2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
AH4AK4_3737	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
AH4AK4_3738	ENOG4105CKI	cobalamin synthesis protein
AH4AK4_3740	ENOG4105E82	cytochrome subunit of dehydrogenase
AH4AK4_3741	ENOG4108MGI	Transcriptional regulator
AH4AK4_3742	ENOG4105EXG	Transcriptional regulator
AH4AK4_3743	ENOG4105F6U	Short-chain dehydrogenase reductase Sdr
AH4AK4_3744	ENOG4105BZU	Histidine kinase
AH4AK4_3745	ENOG4105BZU	Histidine kinase
AH4AK4_3746	ENOG4107QIJ	Aconitate hydratase 2
AH4AK4_3747	ENOG4105D78	K07001 NTE family protein
AH4AK4_3748	ENOG4108N3W	hemolysin secretion protein
AH4AK4_3749	ENOG4108N3W	hemolysin secretion protein
AH4AK4_3751	ENOG4105BZU	Histidine kinase
AH4AK4_3752	ENOG4107QN2	dihydrolipoyl dehydrogenase
AH4AK4_3753	ENOG4107QSN	dihydrolipoamide acetyltransferase
AH4AK4_3754	ENOG4105DAQ	Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) (By similarity)
AH4AK4_3755	ENOG41073TP	transcriptional regulator
AH4AK4_3758	ENOG4105D18	nicotinate-nucleotide pyrophosphorylase
AH4AK4_3759	ENOG4107QHF	type ii secretion system protein e
AH4AK4_3760	ENOG4105D7Q	type ii secretion system
AH4AK4_3763	ENOG4105DHA	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity (By similarity)
AH4AK4_3764	ENOG41067SF	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase (By similarity)
AH4AK4_3765	ENOG4105M6F	mutator MutT protein
AH4AK4_3766	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
AH4AK4_3768	ENOG4105C7C	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
AH4AK4_3769	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
AH4AK4_3770	ENOG4105CIT	This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity)
AH4AK4_3771	ENOG4105K7E	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly (By similarity)
AH4AK4_3772	ENOG4105DFU	Cell wall formation (By similarity)
AH4AK4_3773	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
AH4AK4_3774	ENOG4105CNI	cell division protein FtsW
AH4AK4_3775	ENOG4105DMZ	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity)
AH4AK4_3776	ENOG4105CPY	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity)
AH4AK4_3777	ENOG4108EQQ	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein (By similarity)
AH4AK4_3778	ENOG4107EEN	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity)
AH4AK4_3779	ENOG4105CJN	penicillin-binding protein
AH4AK4_3780	ENOG41063Y6	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity)
AH4AK4_3781	ENOG4105CGJ	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity)
AH4AK4_3782	ENOG4108V6E	Cell division protein mraZ
AH4AK4_3784	ENOG4105E9H	Lytic Murein transglycosylase
AH4AK4_3785	ENOG4105ER2	Ompa motb domain protein
AH4AK4_3786	ENOG4107RD7	Flagellar Motor Protein, MotA
AH4AK4_3791	ENOG4105MQ3	flagellar protein FliS
AH4AK4_3792	ENOG410804A	Flagellar hook-associated 2 domain-containing protein
AH4AK4_3793	ENOG4105I03	Flagellin
AH4AK4_3794	ENOG4105I03	Flagellin
AH4AK4_3795	ENOG4108C80	FliB family
AH4AK4_3797	ENOG4105DTJ	flagellar hook-associated protein
AH4AK4_3798	ENOG4105E1Q	flagellar hook-associated protein
AH4AK4_3800	ENOG4105D92	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity)
AH4AK4_3801	ENOG4107W7W	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity)
AH4AK4_3802	ENOG4105CGA	flagellar basal-body rod protein FlgG
AH4AK4_3803	ENOG4108KPB	Flagellar basal-body rod protein FlgF
AH4AK4_3804	ENOG4105BZE	flagellar hook protein, FlgE
AH4AK4_3805	ENOG4105W00	Flagellar hook capping protein
AH4AK4_3806	ENOG4108ZC9	flagellar basal-body rod protein flgc
AH4AK4_3807	ENOG4105K88	Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body (By similarity)
AH4AK4_3812	ENOG4108JIR	Flagellum-specific ATP synthase
AH4AK4_3814	ENOG4105CS3	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
AH4AK4_3815	ENOG4105C1F	The M ring may be actively involved in energy transduction (By similarity)
AH4AK4_3816	ENOG4105VQ0	flagellar hook-basal body complex protein fliE
AH4AK4_3817	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
AH4AK4_3819	ENOG4105D00	flagellar biosynthetic protein flhB
AH4AK4_3820	ENOG4105D19	Role in flagellar biosynthesis (By similarity)
AH4AK4_3821	ENOG4105VS8	Flagellar biosynthetic protein fliq
AH4AK4_3822	ENOG4105CN7	Flagellar biosynthetic protein FliP
AH4AK4_3823	ENOG4105DD5	Flagellar motor switch protein
AH4AK4_3825	ENOG4105CU0	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity)
AH4AK4_3826	ENOG4105E1C	Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1A (PBP1a) (By similarity)
AH4AK4_3827	ENOG41082RQ	UPF0102 protein
AH4AK4_3828	ENOG4105F55	Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate (By similarity)
AH4AK4_3829	ENOG4105W4M	Transport-associated protein
AH4AK4_3830	ENOG4105KB2	stringent starvation protein b
AH4AK4_3831	ENOG4107MKT	Stringent starvation protein a
AH4AK4_3832	ENOG4105EIX	cytochrome c1
AH4AK4_3833	ENOG4105DJ5	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
AH4AK4_3834	ENOG4108R5F	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
AH4AK4_3835	ENOG4108UJD	30S ribosomal protein S9
AH4AK4_3836	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
AH4AK4_3837	ENOG4105D6Z	AFG1 family ATPase
AH4AK4_3839	ENOG4105C0H	protease
AH4AK4_3840	ENOG4105C0H	protease
AH4AK4_3846	ENOG41069H0	dihydroorotase EC 3.5.2.3
AH4AK4_3850	ENOG41080Z8	PHOSPHOCARRIER protein
AH4AK4_3851	ENOG4105C21	Displays ATPase and GTPase activities (By similarity)
AH4AK4_3852	ENOG4107RM2	PTS IIA-like nitrogen-regulatory protein PtsN
AH4AK4_3853	ENOG41080QH	sigma 54 modulation protein ribosomal protein S30EA
AH4AK4_3854	ENOG4105DTW	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
AH4AK4_3855	ENOG4108IUZ	ABC transporter
AH4AK4_3856	ENOG4105WI0	lipopolysaccharide transport periplasmic protein lptA
AH4AK4_3857	ENOG4108P1K	Required for the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane (By similarity)
AH4AK4_3858	ENOG4108Z4R	3-deoxy-d-manno-octulosonate 8-phosphate phosphatase
AH4AK4_3859	ENOG4105C2X	Arabinose 5-phosphate isomerase
AH4AK4_3860	ENOG4105DHJ	ABC, transporter
AH4AK4_3861	ENOG4105CY3	ABC transporter, permease
AH4AK4_3862	ENOG4107PE3	Mammalian cell entry related domain protein
AH4AK4_3863	ENOG4105E3I	toluene tolerance
AH4AK4_3865	ENOG4105VFK	BolA family
AH4AK4_3866	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
AH4AK4_3867	ENOG4105CMS	peptidase U62, modulator of DNA gyrase
AH4AK4_3868	ENOG4105N42	UPF0307 protein
AH4AK4_3870	ENOG41090HJ	UPF0265 protein
AH4AK4_3877	ENOG4108JCI	Transcriptional regulator
AH4AK4_3878	ENOG4105DKK	Benzoate
AH4AK4_3880	ENOG4105SYT	Methylenetetrahydrofolate reductase
AH4AK4_3884	ENOG4105EIF	outer membrane protein W
AH4AK4_3886	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
AH4AK4_3887	ENOG41086KC	Transcriptional regulator
AH4AK4_3888	ENOG4108UUM	single-stranded DNA-binding protein
AH4AK4_3892	ENOG4105VEQ	Cold shock protein
AH4AK4_3893	ENOG4105D05	Receptor
AH4AK4_3894	ENOG4105D05	Receptor
AH4AK4_3895	ENOG4105E0F	Histidine kinase
AH4AK4_3896	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
AH4AK4_3899	ENOG4108NVR	Methyl-accepting chemotaxis
AH4AK4_3901	ENOG4105BZU	Histidine kinase
AH4AK4_3902	ENOG4108YZA	Nitrogen regulatory protein pii
AH4AK4_3906	ENOG4108IND	Tetr family transcriptional regulator
AH4AK4_3908	ENOG4105KHA	Glyoxalase Bleomycin resistance protein (Dioxygenase
AH4AK4_3911	ENOG4107QYX	exodeoxyribonuclease v alpha
AH4AK4_3912	ENOG4107QKA	exodeoxyribonuclease V beta
AH4AK4_3913	ENOG4105DSY	exodeoxyribonuclease V, gamma
AH4AK4_3914	ENOG4108VBZ	doxx family
AH4AK4_3915	ENOG4105C2I	pirin domain protein
AH4AK4_3917	ENOG4105CWB	LysR family transcriptional Regulator
AH4AK4_3922	ENOG4105E4X	binding-protein-dependent transport systems inner membrane Component
AH4AK4_3924	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
AH4AK4_3926	ENOG4105BZU	Histidine kinase
AH4AK4_3929	ENOG4105CF7	AraC family transcriptional regulator
AH4AK4_3930	ENOG4105WCN	acetyltransferase
AH4AK4_3931	ENOG4105CH6	catalase
AH4AK4_3935	ENOG410841Q	phosphoesterase PA-phosphatase related protein
AH4AK4_3936	ENOG4105IPI	Membrane
AH4AK4_3939	ENOG4108JU9	GAF modulated sigma54 specific transcriptional regulator Fis family
AH4AK4_3941	ENOG4108UTZ	Dihydroxyacetone kinase
AH4AK4_3942	ENOG4105CMT	Dihydroxyacetone kinase
AH4AK4_3943	ENOG4105C7N	Xanthine uracil vitamin C permease
AH4AK4_3944	ENOG4108CAF	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway (By similarity)
AH4AK4_3950	ENOG4108ZI0	d,d-heptose 1,7-bisphosphate phosphatase
AH4AK4_3951	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
AH4AK4_3952	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
AH4AK4_3953	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
AH4AK4_3954	ENOG4108UKE	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity)
AH4AK4_3955	ENOG4105YKK	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions (By similarity)
AH4AK4_3958	ENOG4105KME	endoribonuclease L-psp
AH4AK4_3959	ENOG4105WWK	YheO domain protein
AH4AK4_3960	ENOG4105D27	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
AH4AK4_3961	ENOG4108IIJ	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
AH4AK4_3962	ENOG4105KBC	Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity)
AH4AK4_3963	ENOG4108VZM	50s ribosomal protein L10
AH4AK4_3964	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
AH4AK4_3965	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
AH4AK4_3966	ENOG4105E5V	Participates in transcription elongation, termination and antitermination (By similarity)
AH4AK4_3967	ENOG4105PM1	preprotein translocase subunit SecE
AH4AK4_3969	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
AH4AK4_3973	ENOG4105CS9	pantothenic acid kinase
AH4AK4_3974	ENOG4105HJX	Biotin- acetyl-CoA-carboxylase ligase
AH4AK4_3975	ENOG4105D4A	Cell wall formation (By similarity)
AH4AK4_3976	ENOG4107ZYR	domain protein
AH4AK4_3978	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
AH4AK4_3979	ENOG4105CUW	cytochrome C-TYPE protein
AH4AK4_3980	ENOG4107QY8	reductase
AH4AK4_3982	ENOG4105IFJ	Histidine kinase
AH4AK4_3983	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
AH4AK4_3986	ENOG4105DQ2	Is probably involved in the electron transfer between its heme and the molybdenum cofactor of the reductase catalytic subunit YedY (By similarity)
AH4AK4_3987	ENOG4105CCD	The exact function is not known. Can catalyze the reduction of a variety of substrates like dimethyl sulfoxide, trimethylamine N-oxide, phenylmethyl sulfoxide and L-methionine sulfoxide. Cannot reduce cyclic N-oxides. Shows no activity as sulfite oxidase (By similarity)
AH4AK4_3988	ENOG4108UQ5	membrane protein YcdZ
AH4AK4_3989	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
AH4AK4_3991	ENOG4107WP9	Histidine kinase
AH4AK4_3994	ENOG410642E	Short chain dehydrogenase
AH4AK4_3995	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
AH4AK4_3998	ENOG4108VVK	transcriptional Regulator, AsnC
AH4AK4_3999	ENOG4105CU9	asparagine synthetase A
AH4AK4_4000	ENOG4107T8T	UPF0173 metal-dependent hydrolase
AH4AK4_4001	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
AH4AK4_4002	ENOG4105DBW	Multi-copper polyphenol oxidoreductase laccase
AH4AK4_4003	ENOG4105C34	Pseudouridine synthase
AH4AK4_4004	ENOG4106SNF	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AH4AK4_4005	ENOG4107QMW	pyridine nucleotide-disulfide oxidoreductase
AH4AK4_4006	ENOG4107R6U	sodium dicarboxylate symporter
AH4AK4_4007	ENOG4105CEM	UPF0597 protein
AH4AK4_4008	ENOG4105C15	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
AH4AK4_4009	ENOG4108IIE	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
AH4AK4_4010	ENOG4108I6A	alcohol dehydrogenase
AH4AK4_4011	ENOG4105CF7	AraC family transcriptional regulator
AH4AK4_4012	ENOG4105QNF	Outer membrane lipoprotein
AH4AK4_4014	ENOG4105C8Q	Methyl-accepting chemotaxis
AH4AK4_4015	ENOG4105DJ4	phosphatidylserine decarboxylase
AH4AK4_4019	ENOG4105CXT	aspartate transcarbamylase
AH4AK4_4020	ENOG4108R9M	Involved in allosteric regulation of aspartate carbamoyltransferase (By similarity)
AH4AK4_4021	ENOG410682Y	Regulates arginine biosynthesis genes (By similarity)
AH4AK4_4022	ENOG4105CSX	c4-dicarboxylate anaerobic carrier
AH4AK4_4023	ENOG4105DBV	ornithine carbamoyltransferase
AH4AK4_4024	ENOG4105C5B	carbamate kinase
AH4AK4_4028	ENOG4105C8Q	Methyl-accepting chemotaxis
AH4AK4_4029	ENOG4108HWV	)-transporter
AH4AK4_4030	ENOG4105C2J	ABC transporter
AH4AK4_4032	ENOG4105CNT	hydrolase family 2
AH4AK4_4033	ENOG41060NJ	transcriptional regulator
AH4AK4_4034	ENOG4105CMR	udp-glucose 4-epimerase
AH4AK4_4035	ENOG4105F0Z	galactose-1-phosphate uridylyltransferase
AH4AK4_4036	ENOG4105CRD	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P) (By similarity)
AH4AK4_4037	ENOG4105ENN	converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose (By similarity)
AH4AK4_4039	ENOG4105CT4	transporter
AH4AK4_4040	ENOG4105W3H	MtN3 and saliva related transmembrane protein
AH4AK4_4041	ENOG4105ETE	Transcriptional regulator (LacI family
AH4AK4_4044	ENOG4105F0P	binding-protein-dependent transport systems inner membrane Component
AH4AK4_4048	ENOG4108KDD	Involved in the transport of maltose and maltodextrins (By similarity)
AH4AK4_4049	ENOG4105CPC	Aldo Keto reductase
AH4AK4_4050	ENOG4105DWR	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity)
AH4AK4_4051	ENOG4108NIX	Factor ChrR
AH4AK4_4052	ENOG4105K6V	RNA polymerase
AH4AK4_4054	ENOG4105C75	arginyL-tRNA synthetase
AH4AK4_4056	ENOG4108R5P	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery (By similarity)
AH4AK4_4057	ENOG4105C4N	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis (By similarity)
AH4AK4_4061	ENOG4105D0S	secretion protein (HlyD
AH4AK4_4062	ENOG4105CJ1	ABC, transporter
AH4AK4_4063	ENOG4107QWP	ABC-2 type transporter
AH4AK4_4064	ENOG4107QWP	ABC-2 type transporter
AH4AK4_4067	ENOG4107QZF	nitrite reductase NADPH large subunit
AH4AK4_4068	ENOG4105WZK	nitrite reductase NADPH small subunit
AH4AK4_4069	ENOG4105WZK	nitrite reductase NADPH small subunit
AH4AK4_4070	ENOG4107V9H	nitrite transporter
AH4AK4_4071	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
AH4AK4_4073	ENOG4105CJW	magnesium transporter
AH4AK4_4074	ENOG4108YYX	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. Modulates RNA-binding and helicase activities of the degradosome (By similarity)
AH4AK4_4075	ENOG4105EX9	Membrane
AH4AK4_4077	ENOG4105CNG	UPF0061 protein
AH4AK4_4078	ENOG4105N7H	Cytochrome
AH4AK4_4079	ENOG4105C9U	ATP-dependent DNA helicase RecQ
AH4AK4_4080	ENOG4108VUY	thioesterase Superfamily protein
AH4AK4_4083	ENOG4108RPX	mosc domain containing protein
AH4AK4_4084	ENOG4105D38	putrescine abc transporter
AH4AK4_4085	ENOG4105F38	ABC transporter, permease
AH4AK4_4086	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
AH4AK4_4087	ENOG4108HM4	ABC transporter
AH4AK4_4090	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
AH4AK4_4092	ENOG4105CFQ	glutamine synthetase
AH4AK4_4093	ENOG4108V7X	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
AH4AK4_4096	ENOG4108RH0	Crea protein
AH4AK4_4097	ENOG4105C5I	Dehydrogenase
AH4AK4_4098	ENOG4105R8A	Heat shock protein
AH4AK4_4101	ENOG4107R28	alpha amylase, catalytic region
AH4AK4_4104	ENOG4107R9T	Catalyzes the formation of 5-methyl-uridine at position 54 (m5U54) in all tRNAs (By similarity)
AH4AK4_4105	ENOG4107EXC	regulatoR
AH4AK4_4106	ENOG4105JJR	Histidine kinase
AH4AK4_4108	ENOG4105C6K	Malic enzyme
AH4AK4_4109	ENOG4105CGD	Nad-dependent epimerase dehydratase
AH4AK4_4110	ENOG4105VFB	Binds the 23S rRNA (By similarity)
AH4AK4_4111	ENOG4105C25	Primosomal protein n'
AH4AK4_4112	ENOG4105UYK	outer membrane protein a
AH4AK4_4113	ENOG4105C7B	Threonine dehydratase
AH4AK4_4114	ENOG4105C01	Dihydroxy-acid dehydratase
AH4AK4_4115	ENOG4105CM2	brancheD-chain amino acid aminotransferase
AH4AK4_4116	ENOG4105P3Y	Acetolactate synthase 2 regulatory subunit
AH4AK4_4118	ENOG4105C0P	Mg chelatase subunit ChlI
AH4AK4_4119	ENOG4106HNH	Acyl-transferase
AH4AK4_4120	ENOG4106HNH	Acyl-transferase
AH4AK4_4122	ENOG4108RWI	nicotinamidase
AH4AK4_4123	ENOG4107RH7	Nicotinate phosphoribosyltransferase
AH4AK4_4124	ENOG4108Z33	Thiol disulfide Interchange Protein
AH4AK4_4125	ENOG4105E27	serine threonine protein kinase
AH4AK4_4127	ENOG4105PC1	Conserved Protein
AH4AK4_4131	ENOG4107QP2	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
AH4AK4_4132	ENOG4105ED0	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates (By similarity)
AH4AK4_4133	ENOG4105DSJ	YicC domain protein
AH4AK4_4135	ENOG4105D8A	3-Deoxy-D-manno-octulosonic-acid transferase
AH4AK4_4136	ENOG4105XA0	heptosyltransferase ii
AH4AK4_4137	ENOG4106WTF	Glycosyl transferase, family 2
AH4AK4_4138	ENOG4105M5K	heptosyltransferase
AH4AK4_4139	ENOG4108ZEF	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity)
AH4AK4_4140	ENOG4108MJ5	VirK protein
AH4AK4_4141	ENOG4105ERD	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity)
AH4AK4_4143	ENOG4105W0E	50S ribosomal protein L33
AH4AK4_4144	ENOG4105W5Q	DNA repair protein (RadC
AH4AK4_4145	ENOG4105CJS	Phosphopantothenoylcysteine decarboxylase
AH4AK4_4146	ENOG4108Z1K	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA (By similarity)
AH4AK4_4147	ENOG4105EC0	Required for nucleoid occlusion (NO) phenomenon, which prevents Z-ring formation and cell division over the nucleoid. Acts as a DNA-associated cell division inhibitor that binds simultaneously chromosomal DNA and FtsZ, and disrupts the assembly of FtsZ polymers. SlmA-DNA-binding sequences (SBS) are dispersed on non-Ter regions of the chromosome, preventing FtsZ polymerization at these regions (By similarity)
AH4AK4_4148	ENOG4105D64	Mechanosensitive ion channel
AH4AK4_4149	ENOG4107QP8	phosphohexose isomerase
AH4AK4_4150	ENOG4105C6M	Alpha-keto-beta-hydroxylacyl reductoisomerase
AH4AK4_4151	ENOG4105EMY	transcriptional regulator
AH4AK4_4153	ENOG4105CD5	CoA-binding domain protein
AH4AK4_4159	ENOG4108RR8	protoporphyrinogen oxidase
AH4AK4_4160	ENOG4105D37	Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA (By similarity)
AH4AK4_4161	ENOG4108ZK7	protein family UPF0029, Impact, N-terminal protein
AH4AK4_4162	ENOG4105D9Y	Splits dipeptides with a prolyl residue in the C- terminal position (By similarity)
AH4AK4_4163	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
AH4AK4_4164	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
AH4AK4_4165	ENOG4105CHU	acetyl-coa acetyltransferase
AH4AK4_4166	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
AH4AK4_4167	ENOG4105E0F	Histidine kinase
AH4AK4_4171	ENOG41082K8	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Interacts with IscS and stimulates its activity. Then, accepts a sulfur from IscS and transfers it in turn to TusD (By similarity)
AH4AK4_4172	ENOG4105M4H	endoribonuclease L-psp
AH4AK4_4173	ENOG4108ZG0	Ompa motb domain protein
AH4AK4_4178	ENOG4108R3E	Dna-3-methyladenine glycosylase i
AH4AK4_4179	ENOG4108HMW	glycyl-tRNA synthetase, alpha subunit
AH4AK4_4180	ENOG4105C38	Glycyl-tRNA synthetase beta subunit
AH4AK4_4184	ENOG4108ZHR	arsR family transcriptional regulator
AH4AK4_4186	ENOG4105CIC	tryptophan-specific transport protein
AH4AK4_4187	ENOG4105CIC	tryptophan-specific transport protein
AH4AK4_4188	ENOG4105C0F	tryptophanase EC 4.1.99.1
AH4AK4_4191	ENOG4108EQM	faD-dependent pyridine nucleotide-disulfide oxidoreductase
AH4AK4_4192	ENOG4105CNW	domain protein
AH4AK4_4193	ENOG4108JUA	Transcriptional regulator
AH4AK4_4194	ENOG4105ETE	Transcriptional regulator (LacI family
AH4AK4_4195	ENOG4105CP9	extracellular ligand-binding receptor
AH4AK4_4196	ENOG4105C32	Amino acid ABC transporter (Permease)
AH4AK4_4197	ENOG4105CF8	branched-chain amino acid ABC transporter, permease
AH4AK4_4198	ENOG4105C0Z	ABC transporter
AH4AK4_4199	ENOG4108IV0	ABC, transporter
AH4AK4_4202	ENOG4105M78	Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide (By similarity)
AH4AK4_4205	ENOG4105W0Z	cytoplasmic protein
AH4AK4_4206	ENOG4107QK7	reductase
AH4AK4_4207	ENOG4105D3H	Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol (By similarity)
AH4AK4_4209	ENOG4105C4P	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity)
AH4AK4_4210	ENOG4105K63	Thioredoxin
AH4AK4_4211	ENOG4105C1J	atp-dependent rna helicase
AH4AK4_4212	ENOG4105C9X	ppx gppa phosphatase
AH4AK4_4215	ENOG4105FFN	Specifically methylates the guanosine in position 1516 of 16S rRNA (By similarity)
AH4AK4_4216	ENOG4105BZU	Histidine kinase
AH4AK4_4218	ENOG4105DGW	oligopeptidase A
AH4AK4_4219	ENOG4105D52	delta-aminolevulinic acid dehydratase
AH4AK4_4220	ENOG4105F8V	Hydrolase, tatD family
AH4AK4_4221	ENOG4105DCX	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity)
AH4AK4_4222	ENOG4105X8U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation (By similarity)
AH4AK4_4223	ENOG4105WKS	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity)
AH4AK4_4224	ENOG4105CNK	Required, probably indirectly, for the hydroxylation of 2-octaprenylphenol to 2-octaprenyl-6-hydroxy-phenol, the fourth step in ubiquinone biosynthesis (By similarity)
AH4AK4_4225	ENOG4105JC1	sterol-binding domain protein
AH4AK4_4226	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
AH4AK4_4227	ENOG4105WMR	Protein CrcB homolog
AH4AK4_4228	ENOG4105DZC	cytosine deaminase
AH4AK4_4236	ENOG410822N	TonB family
AH4AK4_4237	ENOG4109015	Biopolymer transport protein exbD tolR
AH4AK4_4241	ENOG4105VJY	transcriptional regulator
AH4AK4_4242	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
AH4AK4_4243	ENOG410804X	Transcriptional regulator
AH4AK4_4244	ENOG4105E3W	Two component transcriptional regulator (Winged helix family
AH4AK4_4245	ENOG4105EB3	Histidine kinase
AH4AK4_4247	ENOG4105CT7	inner membrane cred family protein
AH4AK4_4248	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
AH4AK4_4249	ENOG4105KNM	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
AH4AK4_4250	ENOG4105C4J	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity)
AH4AK4_4251	ENOG4105J80	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity)
AH4AK4_4252	ENOG4105CDG	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity)
AH4AK4_4253	ENOG4107S15	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
AH4AK4_4254	ENOG4107Z6K	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
AH4AK4_4255	ENOG4105KY6	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
AH4AK4_4256	ENOG4105EE4	it plays a direct role in the translocation of protons across the membrane (By similarity)
AH4AK4_4257	ENOG4105FA0	parb-like partition protein
AH4AK4_4258	ENOG4107QJE	Chromosome Partitioning Protein
AH4AK4_4259	ENOG4105D28	Specifically methylates the N7 position of a guanine in 16S rRNA (By similarity)
AH4AK4_4260	ENOG4107RE5	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity)
AH4AK4_4261	ENOG4105QTB	Flavodoxin
AH4AK4_4262	ENOG4105E0K	tonB-dependent siderophore receptor
AH4AK4_4263	ENOG4105IBP	Cyclic peptide transporter
AH4AK4_4264	ENOG4105E0A	ABC, transporter
AH4AK4_4265	ENOG4105J76	Periplasmic binding protein
AH4AK4_4266	ENOG4105S6R	Iron-hydroxamate transporter permease subunit
AH4AK4_4267	ENOG4105C1H	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity)
AH4AK4_4268	ENOG4105DHW	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
AH4AK4_4269	ENOG4105NVJ	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme (By similarity)
AH4AK4_4270	ENOG4105CDA	abc transporter atp-binding protein
AH4AK4_4271	ENOG4105E5Q	amino acid AbC transporter
AH4AK4_4272	ENOG4105EAB	amino acid AbC transporter