locus-tag	class	description
GET80_00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
GET80_00010	COG0592	DNA-directed DNA polymerase activity
GET80_00015	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
GET80_00030	COG2378	regulation of single-species biofilm formation
GET80_00035	COG0071	Belongs to the small heat shock protein (HSP20) family
GET80_00040	COG0071	Belongs to the small heat shock protein (HSP20) family
GET80_00045	COG3977	Valine--pyruvate aminotransferase
GET80_00060	COG2814	Major facilitator Superfamily
GET80_00065	COG0745	RESPONSE REGULATOR receiver
GET80_00070	COG2205	protein histidine kinase activity
GET80_00095	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
GET80_00100	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GET80_00100	COG4191	Histidine kinase
GET80_00105	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
GET80_00110	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GET80_00115	COG1309	transcriptional regulator
GET80_00145	COG0561	phosphatase activity
GET80_00150	COG2267	carboxylic ester hydrolase activity
GET80_00155	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
GET80_00160	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
GET80_00165	COG1758	RNA polymerase activity
GET80_00175	COG0859	PFAM glycosyl transferase family 9
GET80_00180	COG3642	lipopolysaccharide core region biosynthetic process
GET80_00220	COG0589	response to stress
GET80_00225	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
GET80_00235	COG1528	Iron-storage protein
GET80_00240	COG2081	HI0933 family
GET80_00245	COG2223	nitrite transmembrane transporter activity
GET80_00265	COG3188	usher protein
GET80_00285	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GET80_00285	COG2205	protein histidine kinase activity
GET80_00295	COG3275	phosphorelay sensor kinase activity
GET80_00300	COG3279	Response regulator of the LytR AlgR family
GET80_00305	COG2223	nitrite transmembrane transporter activity
GET80_00310	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
GET80_00315	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
GET80_00330	COG0583	DNA-binding transcription factor activity
GET80_00335	COG4206	TonB-dependent receptor
GET80_00340	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
GET80_00375	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
GET80_00380	COG2166	iron-sulfur cluster assembly
GET80_00385	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
GET80_00390	COG0210	DNA helicase
GET80_00400	COG3245	cytochrome
GET80_00405	COG1063	alcohol dehydrogenase
GET80_00410	COG0156	8-amino-7-oxononanoate synthase activity
GET80_00420	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GET80_00435	COG3306	glycosyltransferase involved in LPS biosynthesis
GET80_00455	COG1561	YicC-like family, N-terminal region
GET80_00460	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
GET80_00465	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
GET80_00475	COG0789	Transcriptional regulator
GET80_00480	COG5001	Diguanylate cyclase
GET80_00480	COG4251	negative regulation of phosphorylation
GET80_00480	COG3706	GGDEF domain
GET80_00480	COG2203	Gaf domain
GET80_00485	COG3084	Protein conserved in bacteria
GET80_00495	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
GET80_00500	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
GET80_00510	COG1335	isochorismatase
GET80_00520	COG1683	Conserved Protein
GET80_00525	COG0204	Acyl-transferase
GET80_00530	COG0204	Acyl-transferase
GET80_00535	COG0606	chelatase, subunit chli
GET80_00550	COG3978	acetolactate synthase activity
GET80_00560	COG0129	dihydroxy-acid dehydratase activity
GET80_00580	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
GET80_00585	COG0254	rRNA binding
GET80_00590	COG0702	epimerase
GET80_00595	COG0281	malic enzyme
GET80_00605	COG2205	protein histidine kinase activity
GET80_00610	COG0745	RESPONSE REGULATOR receiver
GET80_00615	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
GET80_00650	COG4310	Domain of unknown function (DUF2172)
GET80_00670	COG2089	acid synthase
GET80_00680	COG1083	cytidylyl-transferase
GET80_00695	COG1028	Short-chain dehydrogenase reductase Sdr
GET80_00700	COG0318	PFAM AMP-dependent synthetase and ligase
GET80_00715	COG1215	transferase activity, transferring glycosyl groups
GET80_00755	COG0529	Catalyzes the synthesis of activated sulfate
GET80_00765	COG0574	Belongs to the PEP-utilizing enzyme family
GET80_00765	COG3848	Pyruvate phosphate dikinase
GET80_00770	COG0519	Catalyzes the synthesis of GMP from XMP
GET80_00775	COG4750	Nucleotidyl transferase
GET80_00780	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
GET80_00785	COG1086	Polysaccharide biosynthesis protein
GET80_00790	COG0366	Alpha amylase catalytic
GET80_00805	COG0443	Heat shock 70 kDa protein
GET80_00810	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
GET80_00815	COG3045	CreA protein
GET80_00835	COG0174	glutamine synthetase
GET80_00855	COG3842	ATPase activity
GET80_00860	COG1176	ABC-type spermidine putrescine transport system, permease component I
GET80_00865	COG1177	transmembrane transport
GET80_00870	COG2258	MOSC domain
GET80_00885	COG2050	protein possibly involved in aromatic compounds catabolism
GET80_00890	COG0514	ATP-dependent DNA helicase (RecQ)
GET80_00900	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
GET80_00910	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
GET80_00915	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
GET80_00925	COG2239	Acts as a magnesium transporter
GET80_00930	COG1648	precorrin-2 dehydrogenase activity
GET80_00930	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
GET80_00935	COG2116	formate transmembrane transporter activity
GET80_00945	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
GET80_00955	COG0477	Major facilitator Superfamily
GET80_00965	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
GET80_00970	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
GET80_00990	COG1595	DNA-templated transcription, initiation
GET80_00995	COG3806	Anti-sigma factor
GET80_01000	COG1968	undecaprenyl-diphosphatase activity
GET80_01005	COG0667	Aldo Keto reductase
GET80_01010	COG2017	converts alpha-aldose to the beta-anomer
GET80_01015	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
GET80_01025	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
GET80_01030	COG1609	Transcriptional regulator
GET80_01035	COG3250	beta-galactosidase activity
GET80_01085	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
GET80_01090	COG1288	antiporter activity
GET80_01095	COG1438	arginine binding
GET80_01100	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
GET80_01105	COG0540	Belongs to the ATCase OTCase family
GET80_01125	COG0688	phosphatidylethanolamine metabolic process
GET80_01135	COG0583	DNA-binding transcription factor activity
GET80_01150	COG3040	lipid binding
GET80_01155	COG2207	Transcriptional regulator
GET80_01160	COG1979	alcohol dehydrogenase
GET80_01165	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
GET80_01170	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
GET80_01180	COG3681	Belongs to the UPF0597 family
GET80_01190	COG0446	pyridine nucleotide-disulphide oxidoreductase
GET80_01195	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
GET80_01200	COG0564	pseudouridine synthase activity
GET80_01210	COG0542	response to heat
GET80_01215	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
GET80_01225	COG2502	aspartate--ammonia ligase
GET80_01230	COG1522	sequence-specific DNA binding
GET80_01240	COG5413	integral membrane protein
GET80_01265	COG2205	protein histidine kinase activity
GET80_01275	COG2204	response regulator
GET80_01295	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
GET80_01325	COG0243	molybdopterin cofactor binding
GET80_01330	COG3005	denitrification pathway
GET80_01335	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
GET80_01355	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
GET80_01360	COG0569	domain protein
GET80_01365	COG0812	UDP-N-acetylmuramate dehydrogenase activity
GET80_01390	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
GET80_01405	COG0250	Participates in transcription elongation, termination and antitermination
GET80_01410	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
GET80_01415	COG0081	regulation of translation
GET80_01420	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
GET80_01425	COG0222	ribosome binding
GET80_01430	COG0085	RNA polymerase activity
GET80_01435	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
GET80_01440	COG2964	Protein conserved in bacteria
GET80_01445	COG0251	oxidation-reduction process
GET80_01455	COG2923	Belongs to the DsrF TusC family
GET80_01460	COG2168	tRNA wobble position uridine thiolation
GET80_01465	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
GET80_01470	COG0049	tRNA binding
GET80_01475	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
GET80_01480	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
GET80_01485	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
GET80_01520	COG2252	PERMEase
GET80_01525	COG2376	Dihydroxyacetone kinase
GET80_01530	COG1461	Dihydroxyacetone kinase
GET80_01545	COG3284	Transcriptional regulator
GET80_01555	COG2957	Belongs to the agmatine deiminase family
GET80_01560	COG4221	oxidoreductase activity
GET80_01565	COG0628	permease
GET80_01570	COG0494	nUDIX hydrolase
GET80_01595	COG0753	catalase activity
GET80_01600	COG1247	-acetyltransferase
GET80_01620	COG2203	Gaf domain
GET80_01620	COG2199	diguanylate cyclase activity
GET80_01630	COG3842	ATPase activity
GET80_01640	COG1175	transmembrane transport
GET80_01670	COG0583	DNA-binding transcription factor activity
GET80_01680	COG1741	Belongs to the pirin family
GET80_01685	COG2259	Doxx family
GET80_01690	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
GET80_01695	COG1074	ATP-dependent DNA helicase activity
GET80_01700	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
GET80_01710	COG0346	lactoylglutathione lyase activity
GET80_01755	COG3706	GGDEF domain
GET80_01755	COG2203	Gaf domain
GET80_01755	COG4251	negative regulation of phosphorylation
GET80_01755	COG5001	Diguanylate cyclase
GET80_01760	COG4771	TonB-dependent receptor
GET80_01765	COG1278	Cold shock
GET80_01790	COG0629	single-stranded DNA binding
GET80_01795	COG2197	response regulator
GET80_01800	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
GET80_01810	COG3047	cAMP biosynthetic process
GET80_01815	COG0840	transmembrane signaling receptor activity
GET80_01840	COG3135	benzoate transporter
GET80_01845	COG1396	sequence-specific DNA binding
GET80_01875	COG2926	Belongs to the UPF0265 family
GET80_01885	COG3028	Belongs to the UPF0307 family
GET80_01890	COG0312	modulator of DNA gyrase
GET80_01895	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
GET80_01900	COG5007	Belongs to the BolA IbaG family
GET80_01910	COG2854	intermembrane phospholipid transfer
GET80_01915	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
GET80_01920	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
GET80_01925	COG1127	ABC transporter
GET80_01930	COG0517	IMP dehydrogenase activity
GET80_01930	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
GET80_01935	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
GET80_01940	COG3117	lipopolysaccharide transmembrane transporter activity
GET80_01945	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
GET80_01950	COG1137	ATPase activity
GET80_01955	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
GET80_01965	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
GET80_01970	COG1660	Displays ATPase and GTPase activities
GET80_01975	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
GET80_01980	COG3711	transcriptional antiterminator
GET80_01980	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
GET80_01995	COG3964	amidohydrolase
GET80_02025	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GET80_02030	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GET80_02040	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
GET80_02045	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
GET80_02050	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GET80_02055	COG0723	plastoquinol--plastocyanin reductase activity
GET80_02060	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
GET80_02065	COG2857	Cytochrome c1
GET80_02070	COG0625	glutathione transferase activity
GET80_02075	COG2969	positive regulation of protein catabolic process
GET80_02080	COG2823	Periplasmic or secreted lipoprotein
GET80_02085	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
GET80_02090	COG0792	nuclease activity
GET80_02095	COG3107	peptidoglycan biosynthetic process
GET80_02100	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
GET80_02110	COG2001	Belongs to the MraZ family
GET80_02115	COG0275	rRNA processing
GET80_02120	COG3116	cell division
GET80_02125	COG0768	penicillin binding
GET80_02135	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
GET80_02140	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
GET80_02145	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
GET80_02150	COG0772	Belongs to the SEDS family
GET80_02155	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
GET80_02160	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
GET80_02165	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
GET80_02170	COG0849	cell division
GET80_02175	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
GET80_02180	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
GET80_02190	COG0653	protein targeting
GET80_02200	COG0494	nUDIX hydrolase
GET80_02205	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
GET80_02210	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
GET80_02225	COG1459	type II secretion system
GET80_02230	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
GET80_02260	COG2186	Transcriptional regulator
GET80_02265	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
GET80_02270	COG0508	dehydrogenase complex catalyzes the overall conversion of
GET80_02275	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
GET80_02285	COG0840	transmembrane signaling receptor activity
GET80_02290	COG0840	transmembrane signaling receptor activity
GET80_02295	COG1752	Esterase of the alpha-beta hydrolase superfamily
GET80_02300	COG1049	propionate catabolic process, 2-methylcitrate cycle
GET80_02310	COG1280	lysine exporter protein (LysE YggA)
GET80_02320	COG0523	cobalamin synthesis protein
GET80_02325	COG0477	Major facilitator Superfamily
GET80_02340	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
GET80_02345	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
GET80_02385	COG3314	Sporulation integral membrane protein YlbJ
GET80_02390	COG0784	Response regulator, receiver
GET80_02390	COG0835	chemotaxis
GET80_02395	COG1028	Short-chain dehydrogenase reductase Sdr
GET80_02400	COG1444	tRNA N-acetyltransferase activity
GET80_02425	COG1803	Methylglyoxal synthase
GET80_02440	COG0252	asparaginase activity
GET80_02460	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GET80_02460	COG1263	PTS System
GET80_02465	COG0366	Alpha amylase catalytic
GET80_02470	COG0110	maltose O-acetyltransferase activity
GET80_02475	COG1522	sequence-specific DNA binding
GET80_02480	COG5006	permease, DMT superfamily
GET80_02490	COG1012	belongs to the aldehyde dehydrogenase family
GET80_02495	COG1177	transmembrane transport
GET80_02500	COG1176	ABC-type spermidine putrescine transport system, permease component I
GET80_02505	COG3842	ATPase activity
GET80_02510	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
GET80_02515	COG0583	DNA-binding transcription factor activity
GET80_02520	COG1757	Na H antiporter
GET80_02560	COG0297	glycogen (starch) synthase activity
GET80_02565	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
GET80_02570	COG2813	Specifically methylates the guanine in position
GET80_02575	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
GET80_02580	COG2203	Gaf domain
GET80_02580	COG4251	negative regulation of phosphorylation
GET80_02580	COG5001	Diguanylate cyclase
GET80_02580	COG3706	GGDEF domain
GET80_02590	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
GET80_02600	COG2995	paraquat-inducible protein a
GET80_02605	COG3008	intermembrane lipid transfer
GET80_02605	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
GET80_02610	COG3009	Protein conserved in bacteria
GET80_02615	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
GET80_02615	COG2885	chlorophyll binding
GET80_02625	COG3240	lipase activity
GET80_02630	COG3111	PFAM Bacterial OB fold (BOF) protein
GET80_02640	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
GET80_02645	COG1194	a g-specific adenine glycosylase
GET80_02655	COG3409	Peptidoglycan-binding domain 1 protein
GET80_02655	COG3267	Type II secretory pathway component ExeA
GET80_02660	COG0617	tRNA 3'-terminal CCA addition
GET80_02675	COG1346	cytolysis
GET80_02680	COG1380	Effector of murein hydrolase LrgA
GET80_02685	COG0583	DNA-binding transcription factor activity
GET80_02715	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
GET80_02720	COG0306	phosphate transporter
GET80_02725	COG1392	Phosphate transport regulator
GET80_02740	COG1560	Kdo2-lipid A biosynthetic process
GET80_02745	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
GET80_02745	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
GET80_02750	COG1538	Outer membrane efflux protein
GET80_02755	COG0494	nUDIX hydrolase
GET80_02760	COG3151	Protein conserved in bacteria
GET80_02770	COG3150	esterase
GET80_02775	COG1051	belongs to the nudix hydrolase family
GET80_02790	COG1566	PFAM secretion protein HlyD family protein
GET80_02795	COG1289	transmembrane transporter activity
GET80_02845	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GET80_02865	COG0204	Acyl-transferase
GET80_02870	COG1842	Phage shock protein A
GET80_02885	COG2827	Endonuclease containing a URI domain
GET80_02895	COG2962	Rard protein
GET80_02900	COG1573	uracil-dna glycosylase
GET80_02905	COG0697	spore germination
GET80_02910	COG0583	DNA-binding transcription factor activity
GET80_02915	COG1108	ABC-type Mn2 Zn2 transport systems permease components
GET80_02920	COG1121	(ABC) transporter
GET80_02925	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
GET80_02945	COG0739	heme binding
GET80_02955	COG3068	Protein conserved in bacteria
GET80_02975	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
GET80_02980	COG1546	Belongs to the CinA family
GET80_02985	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
GET80_02995	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
GET80_03000	COG0527	aspartate kinase activity
GET80_03005	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
GET80_03040	COG1686	Belongs to the peptidase S11 family
GET80_03045	COG0586	Pfam SNARE associated Golgi protein
GET80_03050	COG1253	flavin adenine dinucleotide binding
GET80_03055	COG0525	valine-tRNA ligase activity
GET80_03060	COG2927	DNA polymerase III (CHI subunit)
GET80_03065	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
GET80_03070	COG0795	lipopolysaccharide-transporting ATPase activity
GET80_03075	COG0795	lipopolysaccharide-transporting ATPase activity
GET80_03090	COG0004	ammonium transporteR
GET80_03095	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
GET80_03105	COG2165	general secretion pathway protein
GET80_03110	COG0084	hydrolase, TatD family'
GET80_03115	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
GET80_03125	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
GET80_03130	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
GET80_03135	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
GET80_03140	COG0813	purine-nucleoside phosphorylase activity
GET80_03145	COG5001	Diguanylate cyclase
GET80_03145	COG5002	protein histidine kinase activity
GET80_03145	COG3447	MASE1 domain protein
GET80_03155	COG0560	Phosphoserine phosphatase
GET80_03180	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
GET80_03190	COG0776	regulation of translation
GET80_03205	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
GET80_03210	COG0735	belongs to the Fur family
GET80_03235	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
GET80_03240	COG0513	Belongs to the DEAD box helicase family
GET80_03245	COG3022	response to hydroperoxide
GET80_03260	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
GET80_03265	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
GET80_03270	COG0762	integral membrane protein
GET80_03275	COG1872	DUF167
GET80_03290	COG4166	transmembrane transport
GET80_03310	COG1024	Enoyl-CoA hydratase
GET80_03325	COG4221	oxidoreductase activity
GET80_03330	COG0442	prolyl-tRNA aminoacylation
GET80_03335	COG0840	transmembrane signaling receptor activity
GET80_03340	COG0632	four-way junction helicase activity
GET80_03345	COG2255	four-way junction helicase activity
GET80_03350	COG1271	oxidase subunit
GET80_03355	COG1294	oxidase, subunit
GET80_03360	COG4890	Cyd operon protein YbgT
GET80_03365	COG3790	cyd operon protein YbgE
GET80_03370	COG0824	Thioesterase
GET80_03375	COG0811	peptide transport
GET80_03390	COG0823	Involved in the tonB-independent uptake of proteins
GET80_03395	COG2885	chlorophyll binding
GET80_03400	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
GET80_03475	COG0840	transmembrane signaling receptor activity
GET80_03480	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
GET80_03485	COG0676	glucose-6-phosphate 1-epimerase activity
GET80_03490	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
GET80_03495	COG1640	4-alpha-glucanotransferase
GET80_03500	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
GET80_03520	COG1051	belongs to the nudix hydrolase family
GET80_03525	COG2130	NADP-dependent
GET80_03530	COG1764	response to oxidative stress
GET80_03535	COG1846	Transcriptional regulator
GET80_03570	COG0561	phosphatase activity
GET80_03585	COG0733	neurotransmitter:sodium symporter activity
GET80_03595	COG0733	neurotransmitter:sodium symporter activity
GET80_03620	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GET80_03630	COG1794	racemase activity, acting on amino acids and derivatives
GET80_03645	COG2731	YhcH YjgK YiaL family protein
GET80_03655	COG0668	transmembrane transport
GET80_03660	COG1376	ErfK ybiS ycfS ynhG family protein
GET80_03665	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GET80_03705	COG0583	DNA-binding transcription factor activity
GET80_03710	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
GET80_03720	COG0488	(ABC) transporter
GET80_03725	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
GET80_03725	COG0517	IMP dehydrogenase activity
GET80_03730	COG1585	Membrane protein implicated in regulation of membrane protease activity
GET80_03735	COG0330	HflC and HflK could
GET80_03740	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
GET80_03740	COG1648	precorrin-2 dehydrogenase activity
GET80_03745	COG0175	sulfate reduction
GET80_03750	COG2895	sulfate adenylyltransferase (ATP) activity
GET80_03755	COG0471	metal ion transport
GET80_03755	COG3273	potassium ion transport
GET80_03760	COG0529	Catalyzes the synthesis of activated sulfate
GET80_03810	COG1136	(ABC) transporter
GET80_03825	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
GET80_03845	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
GET80_03850	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
GET80_03855	COG0163	prenyltransferase activity
GET80_03870	COG1131	(ABC) transporter
GET80_03875	COG0842	Transport permease protein
GET80_03880	COG1775	2-hydroxyglutaryl-CoA dehydratase, D-component
GET80_03885	COG1924	4 iron, 4 sulfur cluster binding
GET80_03905	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
GET80_03910	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
GET80_03925	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
GET80_03930	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
GET80_03935	COG1489	DNA binding
GET80_03945	COG1643	Atp-dependent helicase
GET80_03950	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
GET80_03955	COG0346	lactoylglutathione lyase activity
GET80_03965	COG2076	Multidrug Resistance protein
GET80_03975	COG0784	Response regulator, receiver
GET80_03975	COG3437	response regulator, receiver
GET80_03985	COG0671	phosphoesterase, PA-phosphatase related
GET80_04000	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
GET80_04005	COG0038	chloride channel
GET80_04015	COG0316	Belongs to the HesB IscA family
GET80_04040	COG1280	lysine exporter protein (LysE YggA)
GET80_04045	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
GET80_04060	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GET80_04090	COG0745	RESPONSE REGULATOR receiver
GET80_04095	COG3104	oligopeptide transport
GET80_04100	COG1210	Utp--glucose-1-phosphate uridylyltransferase
GET80_04105	COG1555	photosystem II stabilization
GET80_04115	COG2350	Protein conserved in bacteria
GET80_04120	COG2917	probably involved in intracellular septation
GET80_04125	COG0076	glutamate decarboxylase activity
GET80_04130	COG1272	protein, Hemolysin III
GET80_04135	COG2985	domain, Protein
GET80_04135	COG0569	domain protein
GET80_04145	COG0784	Response regulator, receiver
GET80_04145	COG0835	chemotaxis
GET80_04150	COG2755	lipolytic protein G-D-S-L family
GET80_04155	COG4181	ATPase activity
GET80_04160	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
GET80_04165	COG1090	epimerase
GET80_04170	COG2200	EAL domain
GET80_04175	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GET80_04180	COG4935	Belongs to the peptidase S8 family
GET80_04180	COG2234	aminopeptidase activity
GET80_04185	COG0220	tRNA (guanine-N7-)-methyltransferase activity
GET80_04190	COG3171	Protein conserved in bacteria
GET80_04195	COG2066	Belongs to the glutaminase family
GET80_04200	COG2897	thiosulfate sulfurtransferase activity
GET80_04205	COG1404	Belongs to the peptidase S8 family
GET80_04215	COG1132	(ABC) transporter
GET80_04250	COG3076	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome
GET80_04255	COG5001	Diguanylate cyclase
GET80_04255	COG3300	MHYT domain
GET80_04265	COG2207	Transcriptional regulator
GET80_04270	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
GET80_04275	COG3059	membrane
GET80_04290	COG4628	conserved protein (DUF2132)
GET80_04295	COG0688	phosphatidylethanolamine metabolic process
GET80_04300	COG1162	GTPase activity
GET80_04305	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
GET80_04345	COG1278	Cold shock
GET80_04355	COG0840	transmembrane signaling receptor activity
GET80_04360	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
GET80_04410	COG0848	biopolymer transport protein
GET80_04415	COG0811	peptide transport
GET80_04420	COG0811	peptide transport
GET80_04430	COG4206	TonB-dependent receptor
GET80_04435	COG4174	ABC transporter (Permease)
GET80_04440	COG4239	(ABC) transporter, permease
GET80_04450	COG0444	Belongs to the ABC transporter superfamily
GET80_04455	COG4608	Belongs to the ABC transporter superfamily
GET80_04465	COG2195	Cleaves the N-terminal amino acid of tripeptides
GET80_04475	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
GET80_04480	COG1073	alpha beta
GET80_04495	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
GET80_04525	COG0243	molybdopterin cofactor binding
GET80_04540	COG1116	anion transmembrane transporter activity
GET80_04540	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
GET80_04545	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
GET80_04550	COG1116	anion transmembrane transporter activity
GET80_04555	COG2146	nitrite reductase [NAD(P)H] activity
GET80_04555	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
GET80_04560	COG2146	nitrite reductase [NAD(P)H] activity
GET80_04560	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
GET80_04565	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GET80_04570	COG2313	pseudouridylate synthase activity
GET80_04580	COG1858	cytochrome C peroxidase
GET80_04615	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
GET80_04620	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
GET80_04645	COG2986	histidine ammonia-lyase
GET80_04670	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
GET80_04680	COG1028	Short-chain dehydrogenase reductase Sdr
GET80_04685	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
GET80_04695	COG0521	Mo-molybdopterin cofactor biosynthetic process
GET80_04705	COG2966	Psort location CytoplasmicMembrane, score
GET80_04710	COG3610	response to peptide
GET80_04730	COG4175	Glycine betaine
GET80_04735	COG4176	ABC-type proline glycine betaine transport system permease component
GET80_04740	COG2113	Glycine betaine
GET80_04745	COG0175	sulfate reduction
GET80_04750	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
GET80_04755	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
GET80_04760	COG0384	phenazine biosynthesis protein PhzF
GET80_04765	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
GET80_04780	COG0786	glutamate:sodium symporter activity
GET80_04785	COG0252	asparaginase activity
GET80_04790	COG3139	Protein of unknown function (DUF1315)
GET80_04810	COG0616	signal peptide processing
GET80_04815	COG1902	pentaerythritol trinitrate reductase activity
GET80_04815	COG0446	pyridine nucleotide-disulphide oxidoreductase
GET80_04820	COG0778	Nitroreductase
GET80_04830	COG2264	protein methyltransferase activity
GET80_04835	COG0604	alcohol dehydrogenase
GET80_04840	COG0583	DNA-binding transcription factor activity
GET80_04845	COG1263	PTS System
GET80_04845	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GET80_04845	COG2190	(PTS) system
GET80_04850	COG4145	pantothenate transmembrane transporter activity
GET80_04860	COG0439	Biotin carboxylase
GET80_04865	COG0511	ligase activity, forming carbon-carbon bonds
GET80_04870	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
GET80_04875	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
GET80_04885	COG5001	Diguanylate cyclase
GET80_04885	COG3300	MHYT domain
GET80_04905	COG3381	protein complex oligomerization
GET80_04915	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
GET80_04925	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
GET80_04930	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
GET80_04930	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
GET80_04950	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
GET80_04955	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
GET80_04960	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
GET80_04965	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
GET80_04970	COG4172	Belongs to the ABC transporter superfamily
GET80_04980	COG0601	transmembrane transport
GET80_04990	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
GET80_04995	COG0142	geranyltranstransferase activity
GET80_05000	COG1722	exodeoxyribonuclease VII activity
GET80_05005	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
GET80_05010	COG1360	Flagellar Motor Protein
GET80_05025	COG1534	Rna-binding protein
GET80_05030	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
GET80_05040	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
GET80_05045	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
GET80_05050	COG0149	triose-phosphate isomerase activity
GET80_05055	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
GET80_05070	COG0779	Required for maturation of 30S ribosomal subunits
GET80_05075	COG0195	Participates in both transcription termination and antitermination
GET80_05080	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
GET80_05085	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
GET80_05090	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
GET80_05095	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
GET80_05100	COG1185	polyribonucleotide nucleotidyltransferase activity
GET80_05105	COG2211	Major facilitator Superfamily
GET80_05115	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
GET80_05125	COG0114	fumarate hydratase activity
GET80_05135	COG1966	Carbon starvation protein
GET80_05140	COG3279	Response regulator of the LytR AlgR family
GET80_05145	COG3275	phosphorelay sensor kinase activity
GET80_05210	COG0312	modulator of DNA gyrase
GET80_05215	COG0312	modulator of DNA gyrase
GET80_05225	COG4974	Belongs to the 'phage' integrase family
GET80_05230	COG1970	mechanosensitive ion channel activity
GET80_05235	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
GET80_05245	COG0789	Transcriptional regulator
GET80_05260	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
GET80_05265	COG3545	Serine hydrolase
GET80_05275	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
GET80_05285	COG0321	lipoyl(octanoyl) transferase activity
GET80_05290	COG2921	Belongs to the UPF0250 family
GET80_05295	COG1686	Belongs to the peptidase S11 family
GET80_05300	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
GET80_05305	COG2951	lytic endotransglycosylase activity
GET80_05310	COG0772	Belongs to the SEDS family
GET80_05315	COG0768	penicillin binding
GET80_05320	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
GET80_05325	COG0799	negative regulation of ribosome biogenesis
GET80_05330	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
GET80_05350	COG0495	leucyl-tRNA aminoacylation
GET80_05355	COG2888	peptidyl-tyrosine sulfation
GET80_05360	COG0815	Transfers the fatty acyl group on membrane lipoproteins
GET80_05365	COG4535	Mg2 and Co2 transporter CorC
GET80_05370	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
GET80_05375	COG1702	phosphate starvation-inducible protein PhoH
GET80_05380	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
GET80_05385	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
GET80_05390	COG1335	isochorismatase
GET80_05400	COG3706	GGDEF domain
GET80_05415	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
GET80_05435	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
GET80_05445	COG3647	Membrane
GET80_05450	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
GET80_05465	COG0516	GMP reductase activity
GET80_05485	COG0642	Histidine kinase
GET80_05525	COG3214	Protein conserved in bacteria
GET80_05550	COG3029	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
GET80_05555	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
GET80_05560	COG1053	succinate dehydrogenase
GET80_05570	COG0584	glycerophosphoryl diester phosphodiesterase
GET80_05575	COG1511	domain protein
GET80_05575	COG3264	Mechanosensitive ion channel
GET80_05585	COG0739	heme binding
GET80_05600	COG0583	DNA-binding transcription factor activity
GET80_05620	COG0583	DNA-binding transcription factor activity
GET80_05625	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
GET80_05655	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
GET80_05660	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
GET80_05670	COG0338	D12 class N6 adenine-specific DNA methyltransferase
GET80_05690	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
GET80_05700	COG0180	Tryptophanyl-tRNA synthetase
GET80_05715	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
GET80_05725	COG1012	belongs to the aldehyde dehydrogenase family
GET80_05765	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
GET80_05775	COG1013	pyruvate-flavodoxin oxidoreductase activity
GET80_05775	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
GET80_05775	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
GET80_05775	COG0674	pyruvate-flavodoxin oxidoreductase activity
GET80_05785	COG0366	Alpha amylase catalytic
GET80_05795	COG3097	Belongs to the UPF0267 family
GET80_05815	COG0471	metal ion transport
GET80_05815	COG0490	domain, Protein
GET80_05865	COG0012	GTP binding
GET80_05870	COG0193	aminoacyl-tRNA hydrolase activity
GET80_05875	COG0737	Belongs to the 5'-nucleotidase family
GET80_05880	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
GET80_05890	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
GET80_05895	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
GET80_05900	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
GET80_05905	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
GET80_05910	COG2890	protein-(glutamine-N5) methyltransferase activity
GET80_05920	COG2912	Transglutaminase-like superfamily
GET80_05925	COG2877	3-deoxy-8-phosphooctulonate synthase activity
GET80_05930	COG1301	dicarboxylic acid transport
GET80_05940	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
GET80_05955	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
GET80_05960	COG1115	amino acid carrier protein
GET80_05975	COG0714	Associated with various cellular activities
GET80_06000	COG3104	oligopeptide transport
GET80_06005	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
GET80_06010	COG1678	Uncharacterized ACR, COG1678
GET80_06020	COG0189	ligase activity
GET80_06025	COG1385	rRNA (uridine-N3-)-methyltransferase activity
GET80_06035	COG3091	SprT-like family
GET80_06045	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
GET80_06070	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
GET80_06075	COG0739	heme binding
GET80_06080	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
GET80_06085	COG3408	Glycogen debranching enzyme
GET80_06085	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
GET80_06095	COG1881	PFAM PEBP family protein
GET80_06100	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
GET80_06105	COG0583	DNA-binding transcription factor activity
GET80_06115	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
GET80_06125	COG0583	DNA-binding transcription factor activity
GET80_06130	COG1028	Short-chain dehydrogenase reductase Sdr
GET80_06135	COG0616	signal peptide processing
GET80_06140	COG3724	N-succinylarginine dihydrolase activity
GET80_06160	COG0840	transmembrane signaling receptor activity
GET80_06170	COG2971	BadF BadG BcrA BcrD
GET80_06180	COG4608	Belongs to the ABC transporter superfamily
GET80_06185	COG0444	Belongs to the ABC transporter superfamily
GET80_06190	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GET80_06195	COG0601	transmembrane transport
GET80_06200	COG4166	transmembrane transport
GET80_06205	COG0784	Response regulator, receiver
GET80_06205	COG2205	protein histidine kinase activity
GET80_06235	COG3220	belongs to the UPF0276 family
GET80_06265	COG1289	transmembrane transporter activity
GET80_06275	COG0746	molybdenum cofactor guanylyltransferase activity
GET80_06285	COG4662	Binding-protein-dependent transport system inner membrane component
GET80_06295	COG2204	response regulator
GET80_06300	COG3852	Histidine kinase
GET80_06305	COG1910	domain protein
GET80_06310	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
GET80_06345	COG3383	formate dehydrogenase (NAD+) activity
GET80_06345	COG3383	formate dehydrogenase (NAD+) activity
GET80_06350	COG0437	4 iron, 4 sulfur cluster binding
GET80_06365	COG0281	malic enzyme
GET80_06385	COG2706	6-phosphogluconolactonase activity
GET80_06395	COG1196	nuclear chromosome segregation
GET80_06395	COG3264	Mechanosensitive ion channel
GET80_06400	COG0469	pyruvate kinase activity
GET80_06415	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
GET80_06415	COG4651	solute:proton antiporter activity
GET80_06425	COG2974	May be involved in recombination
GET80_06435	COG0420	3'-5' exonuclease activity
GET80_06440	COG0419	ATPase involved in DNA repair
GET80_06450	COG3038	cytochrome b561
GET80_06460	COG3706	GGDEF domain
GET80_06465	COG2190	(PTS) system
GET80_06475	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
GET80_06480	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
GET80_06485	COG0542	response to heat
GET80_06500	COG1720	tRNA m6t6A37 methyltransferase activity
GET80_06520	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
GET80_06525	COG4988	ABC transporter
GET80_06540	COG0745	RESPONSE REGULATOR receiver
GET80_06550	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
GET80_06565	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
GET80_06570	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
GET80_06585	COG0083	homoserine kinase activity
GET80_06590	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
GET80_06595	COG4319	ketosteroid isomerase
GET80_06610	COG0488	(ABC) transporter
GET80_06625	COG0813	purine-nucleoside phosphorylase activity
GET80_06640	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GET80_06640	COG2205	protein histidine kinase activity
GET80_06645	COG3384	dioxygenase
GET80_06655	COG1283	sodium-dependent phosphate transmembrane transporter activity
GET80_06665	COG0531	amino acid
GET80_06670	COG0531	amino acid
GET80_06685	COG1917	Cupin 2, conserved barrel domain protein
GET80_06685	COG1396	sequence-specific DNA binding
GET80_06690	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
GET80_06705	COG3152	Membrane
GET80_06725	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
GET80_06730	COG2375	cellular response to nickel ion
GET80_06740	COG0577	efflux transmembrane transporter activity
GET80_06740	COG1136	(ABC) transporter
GET80_06745	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GET80_06755	COG1227	inorganic diphosphatase activity
GET80_06760	COG0497	DNA recombination
GET80_06765	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
GET80_06770	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
GET80_06775	COG0443	Heat shock 70 kDa protein
GET80_06780	COG0484	heat shock protein binding
GET80_06810	COG1285	pathogenesis
GET80_06825	COG0640	Transcriptional regulator
GET80_06855	COG0095	Lipoate-protein ligase
GET80_06875	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
GET80_06880	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GET80_06900	COG0708	Exodeoxyribonuclease III
GET80_06915	COG2211	Major facilitator Superfamily
GET80_06960	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
GET80_06965	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
GET80_06970	COG1845	cytochrome c oxidase, subunit III
GET80_06975	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
GET80_06980	COG0109	protoheme IX farnesyltransferase activity
GET80_06985	COG2814	Major facilitator Superfamily
GET80_06995	COG2175	clavaminate synthase activity
GET80_07000	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
GET80_07005	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
GET80_07010	COG4521	taurine ABC transporter
GET80_07020	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
GET80_07105	COG0159	tryptophan synthase activity
GET80_07110	COG0133	tryptophan synthase activity
GET80_07115	COG0134	indole-3-glycerol-phosphate synthase activity
GET80_07115	COG0135	phosphoribosylanthranilate isomerase activity
GET80_07120	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
GET80_07125	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
GET80_07125	COG0512	Glutamine amidotransferase of anthranilate synthase
GET80_07130	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
GET80_07140	COG0009	L-threonylcarbamoyladenylate synthase
GET80_07150	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
GET80_07160	COG1946	Acyl-CoA thioesterase
GET80_07180	COG1309	transcriptional regulator
GET80_07185	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GET80_07190	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
GET80_07205	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
GET80_07225	COG0110	maltose O-acetyltransferase activity
GET80_07230	COG0110	maltose O-acetyltransferase activity
GET80_07250	COG0110	maltose O-acetyltransferase activity
GET80_07270	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
GET80_07290	COG3132	Protein of unknown function, DUF480
GET80_07330	COG1278	Cold shock
GET80_07365	COG1349	DNA-binding transcription factor activity
GET80_07370	COG1882	Formate acetyltransferase
GET80_07375	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
GET80_07380	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
GET80_07405	COG4166	transmembrane transport
GET80_07410	COG0622	Phosphoesterase
GET80_07425	COG1261	Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly
GET80_07430	COG0784	Response regulator, receiver
GET80_07430	COG0835	chemotaxis
GET80_07435	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
GET80_07440	COG1815	bacterial-type flagellum-dependent cell motility
GET80_07460	COG4787	bacterial-type flagellum-dependent cell motility
GET80_07470	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
GET80_07475	COG1706	bacterial-type flagellum-dependent cell motility
GET80_07485	COG1256	bacterial-type flagellum assembly
GET80_07495	COG2239	Acts as a magnesium transporter
GET80_07505	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
GET80_07510	COG2716	regulation of RNA biosynthetic process
GET80_07535	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
GET80_07540	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
GET80_07545	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
GET80_07550	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
GET80_07570	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
GET80_07580	COG0590	tRNA wobble adenosine to inosine editing
GET80_07585	COG0573	inorganic phosphate transmembrane transporter activity
GET80_07590	COG0581	inorganic phosphate transmembrane transporter activity
GET80_07595	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
GET80_07600	COG0704	Plays a role in the regulation of phosphate uptake
GET80_07605	COG1253	flavin adenine dinucleotide binding
GET80_07620	COG0531	amino acid
GET80_07640	COG1126	abc transporter atp-binding protein
GET80_07645	COG0765	amino acid transport
GET80_07650	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GET80_07660	COG2271	Major facilitator Superfamily
GET80_07675	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
GET80_07700	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
GET80_07705	COG0477	Major facilitator Superfamily
GET80_07710	COG0123	including yeast histone deacetylase and acetoin utilization protein
GET80_07720	COG1199	ATP-dependent helicase activity
GET80_07735	COG1448	Aminotransferase
GET80_07740	COG0433	COG0433 Predicted ATPase
GET80_07755	COG2333	competence protein COMEC
GET80_07755	COG0658	competence protein
GET80_07765	COG1663	tetraacyldisaccharide 4'-kinase activity
GET80_07770	COG2835	tetraacyldisaccharide 4'-kinase activity
GET80_07775	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
GET80_07780	COG2197	response regulator
GET80_07785	COG0322	excinuclease ABC activity
GET80_07840	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
GET80_07845	COG0437	4 iron, 4 sulfur cluster binding
GET80_07850	COG3301	Polysulphide reductase, NrfD
GET80_07855	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
GET80_07865	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
GET80_07905	COG2199	diguanylate cyclase activity
GET80_07905	COG2203	Gaf domain
GET80_07935	COG2119	membrane
GET80_07940	COG0023	Translation Initiation Factor
GET80_07965	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
GET80_07980	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GET80_07980	COG2205	protein histidine kinase activity
GET80_07990	COG4138	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system
GET80_08000	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
GET80_08005	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
GET80_08010	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
GET80_08015	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
GET80_08025	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
GET80_08030	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
GET80_08040	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
GET80_08050	COG0505	Belongs to the CarA family
GET80_08055	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
GET80_08060	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
GET80_08095	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GET80_08100	COG0513	Belongs to the DEAD box helicase family
GET80_08110	COG4104	PAAR repeat-containing protein
GET80_08125	COG0789	Transcriptional regulator
GET80_08140	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GET80_08145	COG0765	amino acid transport
GET80_08150	COG1126	abc transporter atp-binding protein
GET80_08155	COG0493	'glutamate synthase
GET80_08160	COG0067	glutamate synthase
GET80_08160	COG0069	glutamate synthase activity
GET80_08160	COG0070	glutamate synthase
GET80_08165	COG1242	4 iron, 4 sulfur cluster binding
GET80_08220	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
GET80_08225	COG0574	Belongs to the PEP-utilizing enzyme family
GET80_08225	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
GET80_08265	COG1464	Belongs to the NlpA lipoprotein family
GET80_08270	COG0671	phosphoesterase, PA-phosphatase related
GET80_08275	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
GET80_08280	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
GET80_08290	COG0101	tRNA pseudouridine synthase activity
GET80_08295	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
GET80_08300	COG0285	dihydrofolate synthase activity
GET80_08305	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
GET80_08310	COG2920	part of a sulfur-relay system
GET80_08315	COG1289	transmembrane transporter activity
GET80_08320	COG0670	Belongs to the BI1 family
GET80_08340	COG2194	sulfuric ester hydrolase activity
GET80_08350	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
GET80_08350	COG0392	lysyltransferase activity
GET80_08360	COG0840	transmembrane signaling receptor activity
GET80_08365	COG2203	Gaf domain
GET80_08365	COG2199	diguanylate cyclase activity
GET80_08370	COG0564	pseudouridine synthase activity
GET80_08385	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
GET80_08395	COG0625	glutathione transferase activity
GET80_08400	COG0625	glutathione transferase activity
GET80_08410	COG0367	asparagine synthase
GET80_08420	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
GET80_08420	COG4651	solute:proton antiporter activity
GET80_08425	COG0647	UMP catabolic process
GET80_08430	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
GET80_08435	COG1902	pentaerythritol trinitrate reductase activity
GET80_08440	COG1253	flavin adenine dinucleotide binding
GET80_08450	COG0247	lactate metabolic process
GET80_08450	COG0277	FAD linked oxidase domain protein
GET80_08460	COG2050	protein possibly involved in aromatic compounds catabolism
GET80_08470	COG2056	Na+-H+ antiporter family
GET80_08475	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
GET80_08490	COG0346	lactoylglutathione lyase activity
GET80_08495	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
GET80_08500	COG4660	Part of a membrane complex involved in electron transport
GET80_08505	COG4659	FMN binding
GET80_08510	COG4658	electron transport chain
GET80_08520	COG2878	Part of a membrane complex involved in electron transport
GET80_08525	COG4657	Part of a membrane complex involved in electron transport
GET80_08530	COG0697	spore germination
GET80_08550	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
GET80_08555	COG1288	antiporter activity
GET80_08560	COG0436	Aminotransferase
GET80_08570	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
GET80_08575	COG2027	D-alanyl-D-alanine carboxypeptidase
GET80_08580	COG1061	Type III restriction enzyme res subunit
GET80_08585	COG1566	PFAM secretion protein HlyD family protein
GET80_08595	COG1966	Carbon starvation protein
GET80_08600	COG3279	Response regulator of the LytR AlgR family
GET80_08605	COG3275	phosphorelay sensor kinase activity
GET80_08610	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
GET80_08610	COG2199	diguanylate cyclase activity
GET80_08615	COG1454	alcohol dehydrogenase
GET80_08615	COG1012	belongs to the aldehyde dehydrogenase family
GET80_08625	COG2095	MarC family integral membrane protein
GET80_08635	COG0601	transmembrane transport
GET80_08640	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GET80_08655	COG0861	Integral membrane protein TerC family
GET80_08660	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
GET80_08670	COG1301	dicarboxylic acid transport
GET80_08685	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
GET80_08700	COG0537	adenosine 5'-monophosphoramidase activity
GET80_08735	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
GET80_08740	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
GET80_08750	COG2354	Protein conserved in bacteria
GET80_08760	COG1164	Oligoendopeptidase f
GET80_08765	COG2233	PERMEase
GET80_08770	COG3150	esterase
GET80_08775	COG1252	NADH dehydrogenase
GET80_08795	COG0393	Putative heavy-metal-binding
GET80_08805	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
GET80_08805	COG1648	precorrin-2 dehydrogenase activity
GET80_08825	COG4667	esterase of the alpha-beta hydrolase superfamily
GET80_08830	COG1619	proteins homologs of microcin C7 resistance protein MccF
GET80_08835	COG1368	sulfuric ester hydrolase activity
GET80_08845	COG0527	aspartate kinase activity
GET80_08850	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
GET80_08850	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
GET80_08855	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
GET80_08880	COG0596	Alpha beta hydrolase
GET80_08885	COG0346	lactoylglutathione lyase activity
GET80_08895	COG0583	DNA-binding transcription factor activity
GET80_08900	COG1620	l-lactate permease
GET80_08905	COG0247	lactate metabolic process
GET80_08910	COG1139	Iron-sulfur cluster binding protein
GET80_08940	COG0577	efflux transmembrane transporter activity
GET80_08945	COG1136	(ABC) transporter
GET80_08955	COG2814	Major facilitator Superfamily
GET80_08975	COG0672	)-iron permease
GET80_09005	COG0659	secondary active sulfate transmembrane transporter activity
GET80_09025	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
GET80_09030	COG0840	transmembrane signaling receptor activity
GET80_09040	COG2201	protein-glutamate methylesterase activity
GET80_09050	COG0835	chemotaxis
GET80_09055	COG0840	transmembrane signaling receptor activity
GET80_09055	COG3290	protein histidine kinase activity
GET80_09060	COG0643	Histidine kinase
GET80_09060	COG2198	Histidine kinase
GET80_09075	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
GET80_09080	COG0437	4 iron, 4 sulfur cluster binding
GET80_09085	COG5557	Pfam Polysulphide reductase, NrfD
GET80_09090	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
GET80_09095	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
GET80_09100	COG1773	rubredoxin
GET80_09110	COG0601	transmembrane transport
GET80_09115	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GET80_09125	COG3842	ATPase activity
GET80_09130	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
GET80_09135	COG0375	protein maturation
GET80_09140	COG0309	Hydrogenase expression formation protein (HypE)
GET80_09150	COG0298	carbon dioxide binding
GET80_09155	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
GET80_09165	COG1921	L-seryl-tRNASec selenium transferase activity
GET80_09175	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
GET80_09185	COG3260	NADH ubiquinone oxidoreductase 20
GET80_09190	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
GET80_09195	COG3261	NADH dehydrogenase
GET80_09195	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
GET80_09200	COG0650	Formate hydrogenlyase subunit 4
GET80_09205	COG0651	ATP synthesis coupled electron transport
GET80_09210	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
GET80_09215	COG3158	transport of potassium into the cell
GET80_09225	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
GET80_09250	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
GET80_09260	COG0326	Molecular chaperone. Has ATPase activity
GET80_09270	COG0563	adenylate kinase activity
GET80_09275	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
GET80_09280	COG3788	relative of glutathione S-transferase, MAPEG superfamily
GET80_09285	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GET80_09300	COG3300	MHYT domain
GET80_09300	COG5001	Diguanylate cyclase
GET80_09305	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
GET80_09325	COG1021	2,3-dihydroxybenzoate-AMP ligase
GET80_09330	COG3433	isochorismatase activity
GET80_09330	COG1535	isochorismatase
GET80_09335	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GET80_09340	COG1028	Short-chain dehydrogenase reductase Sdr
GET80_09350	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GET80_09355	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
GET80_09365	COG1120	ATPase activity
GET80_09370	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GET80_09375	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GET80_09380	COG4771	TonB-dependent receptor
GET80_09420	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
GET80_09425	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
GET80_09430	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
GET80_09445	COG1570	exodeoxyribonuclease VII activity
GET80_09450	COG0697	spore germination
GET80_09470	COG3158	transport of potassium into the cell
GET80_09475	COG0516	GMP reductase activity
GET80_09475	COG0517	IMP dehydrogenase activity
GET80_09480	COG0519	Catalyzes the synthesis of GMP from XMP
GET80_09480	COG0518	GMP synthase (glutamine-hydrolyzing) activity
GET80_09520	COG2062	phosphohistidine phosphatase, SixA
GET80_09530	COG0697	spore germination
GET80_09535	COG4166	transmembrane transport
GET80_09540	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
GET80_09545	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
GET80_09555	COG4591	ABC-type transport system involved in lipoprotein release permease component
GET80_09560	COG1136	(ABC) transporter
GET80_09565	COG4591	ABC-type transport system involved in lipoprotein release permease component
GET80_09570	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
GET80_09585	COG0544	peptidyl-prolyl cis-trans isomerase activity
GET80_09590	COG0740	serine-type endopeptidase activity
GET80_09595	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
GET80_09600	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
GET80_09605	COG0776	regulation of translation
GET80_09610	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
GET80_09615	COG0488	(ABC) transporter
GET80_09620	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GET80_09625	COG3162	membrane
GET80_09640	COG1024	Enoyl-CoA hydratase
GET80_09645	COG1115	amino acid carrier protein
GET80_09660	COG1584	GPR1 FUN34 yaaH family protein
GET80_09695	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
GET80_09700	COG1960	acyl-CoA dehydrogenase activity
GET80_09710	COG1960	acyl-CoA dehydrogenase activity
GET80_09715	COG1024	Enoyl-CoA hydratase
GET80_09720	COG1024	Enoyl-CoA hydratase
GET80_09730	COG1028	Short-chain dehydrogenase reductase Sdr
GET80_09740	COG0730	response to heat
GET80_09760	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
GET80_09810	COG1598	PFAM Uncharacterised protein family UPF0150
GET80_09835	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
GET80_09840	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
GET80_09845	COG2135	peptidase activity
GET80_09865	COG1073	alpha beta
GET80_09870	COG0583	DNA-binding transcription factor activity
GET80_09875	COG1902	pentaerythritol trinitrate reductase activity
GET80_09895	COG3621	Patatin-like phospholipase
GET80_09945	COG5001	Diguanylate cyclase
GET80_09945	COG3300	MHYT domain
GET80_09950	COG0583	DNA-binding transcription factor activity
GET80_09955	COG2723	6-phospho-beta-galactosidase activity
GET80_09960	COG5001	Diguanylate cyclase
GET80_09960	COG3300	MHYT domain
GET80_09970	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
GET80_09980	COG0583	DNA-binding transcription factor activity
GET80_09985	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
GET80_09990	COG0673	inositol 2-dehydrogenase activity
GET80_09995	COG0583	DNA-binding transcription factor activity
GET80_10005	COG1560	Kdo2-lipid A biosynthetic process
GET80_10010	COG1560	Kdo2-lipid A biosynthetic process
GET80_10035	COG0417	DNA replication proofreading
GET80_10065	COG0534	Mate efflux family protein
GET80_10075	COG0307	riboflavin synthase, alpha
GET80_10085	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
GET80_10090	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
GET80_10095	COG0697	spore germination
GET80_10100	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
GET80_10140	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
GET80_10145	COG3099	Belongs to the UPF0263 family
GET80_10150	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
GET80_10155	COG2894	cell division
GET80_10160	COG0850	regulation of cytokinetic process
GET80_10165	COG3100	YcgL domain-containing protein
GET80_10170	COG2951	lytic endotransglycosylase activity
GET80_10175	COG1760	l-serine dehydratase
GET80_10185	COG1760	l-serine dehydratase
GET80_10190	COG3123	guanosine phosphorylase activity
GET80_10210	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
GET80_10215	COG2067	long-chain fatty acid transport protein
GET80_10230	COG1595	DNA-templated transcription, initiation
GET80_10260	COG0714	Associated with various cellular activities
GET80_10265	COG0183	Belongs to the thiolase family
GET80_10270	COG1024	Enoyl-CoA hydratase
GET80_10270	COG1250	3-hydroxyacyl-CoA dehydrogenase
GET80_10290	COG3829	transcription factor binding
GET80_10295	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
GET80_10300	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
GET80_10305	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
GET80_10315	COG0549	Belongs to the carbamate kinase family
GET80_10320	COG0697	spore germination
GET80_10325	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
GET80_10325	COG3608	succinylglutamate desuccinylase aspartoacylase
GET80_10330	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
GET80_10335	COG2068	MobA-Related Protein
GET80_10340	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
GET80_10340	COG0493	'glutamate synthase
GET80_10345	COG0402	S-adenosylhomocysteine deaminase activity
GET80_10350	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
GET80_10355	COG1529	Aldehyde oxidase and xanthine dehydrogenase
GET80_10355	COG2080	2 iron, 2 sulfur cluster binding
GET80_10360	COG2233	PERMEase
GET80_10365	COG0402	S-adenosylhomocysteine deaminase activity
GET80_10370	COG2252	PERMEase
GET80_10375	COG1529	Aldehyde oxidase and xanthine dehydrogenase
GET80_10380	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
GET80_10385	COG2080	2 iron, 2 sulfur cluster binding
GET80_10395	COG3134	Outer membrane lipoprotein
GET80_10410	COG0318	PFAM AMP-dependent synthetase and ligase
GET80_10425	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
GET80_10425	COG0140	phosphoribosyl-ATP diphosphatase activity
GET80_10430	COG0107	imidazoleglycerol-phosphate synthase activity
GET80_10435	COG2205	protein histidine kinase activity
GET80_10435	COG0784	Response regulator, receiver
GET80_10435	COG2198	Histidine kinase
GET80_10440	COG2199	diguanylate cyclase activity
GET80_10445	COG3437	response regulator, receiver
GET80_10450	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
GET80_10455	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
GET80_10460	COG0131	Imidazoleglycerol-phosphate dehydratase
GET80_10460	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
GET80_10465	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
GET80_10470	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
GET80_10475	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
GET80_10485	COG1199	ATP-dependent helicase activity
GET80_10495	COG1214	PFAM Peptidase M22, glycoprotease
GET80_10505	COG0596	Alpha beta hydrolase
GET80_10505	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
GET80_10505	COG2226	methyltransferase
GET80_10510	COG0318	PFAM AMP-dependent synthetase and ligase
GET80_10515	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
GET80_10530	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
GET80_10535	COG2832	Protein of unknown function (DUF454)
GET80_10540	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
GET80_10550	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
GET80_10555	COG0582	viral genome integration into host DNA
GET80_10660	COG0753	catalase activity
GET80_10720	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
GET80_10725	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
GET80_10885	COG0517	IMP dehydrogenase activity
GET80_10885	COG0617	tRNA 3'-terminal CCA addition
GET80_10885	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
GET80_10890	COG1643	Atp-dependent helicase
GET80_10900	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
GET80_10910	COG3437	response regulator, receiver
GET80_10915	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GET80_10920	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
GET80_10925	COG0709	Synthesizes selenophosphate from selenide and ATP
GET80_10940	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
GET80_10945	COG0840	transmembrane signaling receptor activity
GET80_10950	COG1254	Belongs to the acylphosphatase family
GET80_10955	COG0625	glutathione transferase activity
GET80_10960	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GET80_10960	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GET80_10965	COG0489	protein tyrosine kinase activity
GET80_10970	COG0572	uridine kinase
GET80_10975	COG0717	Belongs to the dCTP deaminase family
GET80_10985	COG0306	phosphate transporter
GET80_10990	COG1530	ribonuclease E activity
GET80_10995	COG0564	pseudouridine synthase activity
GET80_11000	COG0546	phosphoglycolate phosphatase activity
GET80_11005	COG0424	maF-like protein
GET80_11010	COG2814	Major facilitator Superfamily
GET80_11025	COG1399	metal-binding, possibly nucleic acid-binding protein
GET80_11030	COG0333	Belongs to the bacterial ribosomal protein bL32 family
GET80_11035	COG0416	fatty acid biosynthetic process
GET80_11040	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
GET80_11050	COG1028	Short-chain dehydrogenase reductase Sdr
GET80_11055	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
GET80_11060	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
GET80_11065	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
GET80_11070	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
GET80_11075	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
GET80_11080	COG0470	DNA polymerase III
GET80_11085	COG0084	hydrolase, TatD family'
GET80_11100	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
GET80_11100	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
GET80_11105	COG3008	intermembrane lipid transfer
GET80_11110	COG2995	paraquat-inducible protein a
GET80_11120	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
GET80_11125	COG0372	Belongs to the citrate synthase family
GET80_11170	COG4221	oxidoreductase activity
GET80_11180	COG3141	response to X-ray
GET80_11190	COG1067	ATP-dependent peptidase activity
GET80_11195	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
GET80_11210	COG0488	(ABC) transporter
GET80_11220	COG0116	Belongs to the methyltransferase superfamily
GET80_11220	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
GET80_11235	COG0167	dihydroorotate dehydrogenase activity
GET80_11240	COG2902	Dehydrogenase
GET80_11250	COG0308	aminopeptidase N
GET80_11260	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
GET80_11265	COG1956	GAF domain-containing protein
GET80_11275	COG3278	Belongs to the heme-copper respiratory oxidase family
GET80_11290	COG2010	Cytochrome c
GET80_11315	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
GET80_11320	COG0589	response to stress
GET80_11325	COG0037	tRNA processing
GET80_11345	COG1869	D-ribose catabolic process
GET80_11350	COG1129	ABC transporter
GET80_11355	COG1172	Belongs to the binding-protein-dependent transport system permease family
GET80_11360	COG1879	ABC-type sugar transport system periplasmic component
GET80_11365	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GET80_11370	COG1609	Transcriptional regulator
GET80_11375	COG2199	diguanylate cyclase activity
GET80_11400	COG0784	Response regulator, receiver
GET80_11400	COG2205	protein histidine kinase activity
GET80_11405	COG0776	regulation of translation
GET80_11410	COG0072	phenylalanine-tRNA ligase activity
GET80_11410	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GET80_11415	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
GET80_11420	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
GET80_11425	COG0291	Belongs to the bacterial ribosomal protein bL35 family
GET80_11430	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
GET80_11435	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
GET80_11455	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
GET80_11465	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
GET80_11470	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
GET80_11475	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
GET80_11480	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
GET80_11485	COG3313	Fe-S protein
GET80_11490	COG2942	2-epimerase
GET80_11495	COG3716	PTS system mannose fructose sorbose family IID component
GET80_11500	COG3715	PTS system
GET80_11505	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
GET80_11505	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GET80_11520	COG1609	Transcriptional regulator
GET80_11525	COG2140	Oxalate decarboxylase
GET80_11530	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GET80_11530	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
GET80_11530	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GET80_11535	COG1105	Belongs to the carbohydrate kinase PfkB family
GET80_11540	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
GET80_11540	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
GET80_11545	COG1609	Transcriptional regulator
GET80_11550	COG0814	amino acid
GET80_11560	COG5654	RES domain protein
GET80_11565	COG0513	Belongs to the DEAD box helicase family
GET80_11575	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
GET80_11580	COG2890	protein-(glutamine-N5) methyltransferase activity
GET80_11585	COG2840	Smr protein MutS2
GET80_11595	COG3706	GGDEF domain
GET80_11625	COG2824	Alkylphosphonate utilization operon protein PhnA
GET80_11645	COG0384	phenazine biosynthesis protein PhzF
GET80_11675	COG0242	peptide deformylase activity
GET80_11695	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
GET80_11700	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
GET80_11710	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
GET80_11715	COG1434	Gram-negative-bacterium-type cell wall biogenesis
GET80_11725	COG0205	6-phosphofructokinase activity
GET80_11730	COG1473	amidohydrolase
GET80_11735	COG1011	Hydrolase
GET80_11740	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
GET80_11785	COG3593	DNA synthesis involved in DNA repair
GET80_11800	COG0583	DNA-binding transcription factor activity
GET80_11805	COG0730	response to heat
GET80_11810	COG3148	PFAM DTW domain containing protein
GET80_11820	COG1181	Belongs to the D-alanine--D-alanine ligase family
GET80_11835	COG0386	Belongs to the glutathione peroxidase family
GET80_11840	COG0513	Belongs to the DEAD box helicase family
GET80_11845	COG0456	acetyltransferase
GET80_11855	COG1742	UPF0060 membrane protein
GET80_11885	COG2329	Antibiotic biosynthesis monooxygenase
GET80_11890	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
GET80_11910	COG3243	poly(R)-hydroxyalkanoic acid synthase
GET80_11920	COG2501	S4 domain
GET80_11935	COG1132	(ABC) transporter
GET80_11945	COG1132	(ABC) transporter
GET80_11955	COG3118	belongs to the thioredoxin family
GET80_11960	COG0471	metal ion transport
GET80_11965	COG0058	SHG alpha-glucan phosphorylase activity
GET80_12000	COG0814	amino acid
GET80_12005	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
GET80_12010	COG0514	ATP-dependent DNA helicase (RecQ)
GET80_12015	COG2766	serine protein kinase
GET80_12025	COG2719	SpoVR family
GET80_12030	COG2186	Transcriptional regulator
GET80_12035	COG3067	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
GET80_12040	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
GET80_12045	COG0586	Pfam SNARE associated Golgi protein
GET80_12055	COG0556	nucleotide-excision repair
GET80_12070	COG2985	domain, Protein
GET80_12070	COG0569	domain protein
GET80_12075	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
GET80_12095	COG4565	transcriptional regulatory protein
GET80_12100	COG3290	protein histidine kinase activity
GET80_12105	COG1846	Transcriptional regulator
GET80_12105	COG1940	carbohydrate kinase activity
GET80_12110	COG0840	transmembrane signaling receptor activity
GET80_12115	COG3012	SEC-C Motif Domain Protein
GET80_12120	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
GET80_12125	COG3075	Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses fumarate or nitrate as electron acceptor
GET80_12130	COG0247	lactate metabolic process
GET80_12150	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
GET80_12155	COG0437	4 iron, 4 sulfur cluster binding
GET80_12160	COG3301	Polysulphide reductase, NrfD
GET80_12170	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GET80_12175	COG4235	cytochrome complex assembly
GET80_12175	COG3088	subunit of a heme lyase
GET80_12180	COG1051	belongs to the nudix hydrolase family
GET80_12190	COG3033	Beta-eliminating lyase
GET80_12200	COG3046	protein related to deoxyribodipyrimidine photolyase
GET80_12205	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
GET80_12235	COG0516	GMP reductase activity
GET80_12235	COG0517	IMP dehydrogenase activity
GET80_12245	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
GET80_12260	COG4774	siderophore transport
GET80_12265	COG4977	sequence-specific DNA binding
GET80_12275	COG0583	DNA-binding transcription factor activity
GET80_12280	COG2910	NAD(P)H-binding
GET80_12295	COG0612	Peptidase, M16
GET80_12300	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
GET80_12310	COG1944	ATP diphosphatase activity
GET80_12315	COG2116	formate transmembrane transporter activity
GET80_12320	COG1882	Formate acetyltransferase
GET80_12325	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
GET80_12335	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
GET80_12345	COG1840	ABC-type Fe3 transport system, periplasmic component
GET80_12350	COG3842	ATPase activity
GET80_12360	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
GET80_12365	COG2983	Belongs to the UPF0260 family
GET80_12375	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
GET80_12380	COG0045	succinate-CoA ligase (ADP-forming) activity
GET80_12385	COG0508	dehydrogenase complex catalyzes the overall conversion of
GET80_12390	COG0567	Dehydrogenase, E1 component
GET80_12400	COG1053	succinate dehydrogenase
GET80_12405	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
GET80_12430	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
GET80_12435	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
GET80_12435	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
GET80_12445	COG3069	C4-dicarboxylate transmembrane transporter activity
GET80_12460	COG1451	nucleotide metabolic process
GET80_12475	COG0254	rRNA binding
GET80_12480	COG0257	Belongs to the bacterial ribosomal protein bL36 family
GET80_12490	COG0583	DNA-binding transcription factor activity
GET80_12500	COG1172	Belongs to the binding-protein-dependent transport system permease family
GET80_12510	COG1879	ABC-type sugar transport system periplasmic component
GET80_12515	COG1069	ribulokinase activity
GET80_12525	COG2160	L-arabinose isomerase activity
GET80_12530	COG2925	Exonuclease
GET80_12540	COG3345	alpha-galactosidase
GET80_12545	COG1380	Effector of murein hydrolase LrgA
GET80_12550	COG1346	cytolysis
GET80_12555	COG0295	cytidine deaminase activity
GET80_12560	COG1022	Amp-dependent synthetase and ligase
GET80_12575	COG0861	Integral membrane protein TerC family
GET80_12580	COG2885	chlorophyll binding
GET80_12585	COG2199	diguanylate cyclase activity
GET80_12605	COG2154	pterin-4-alpha-carbinolamine dehydratase
GET80_12615	COG3768	UPF0283 membrane protein
GET80_12620	COG3106	COG3106 Predicted ATPase
GET80_12635	COG1842	Phage shock protein A
GET80_12640	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
GET80_12650	COG4168	peptide transport system, permease
GET80_12655	COG4171	peptide transport system, permease
GET80_12665	COG4172	Belongs to the ABC transporter superfamily
GET80_12675	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
GET80_12680	COG1286	toxin biosynthetic process
GET80_12685	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
GET80_12690	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
GET80_12695	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
GET80_12700	COG0531	amino acid
GET80_12700	COG1674	ftsk spoiiie
GET80_12710	COG0686	Belongs to the AlaDH PNT family
GET80_12715	COG0492	ferredoxin-NADP+ reductase activity
GET80_12720	COG3706	GGDEF domain
GET80_12725	COG3134	Outer membrane lipoprotein
GET80_12730	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
GET80_12735	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
GET80_12740	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
GET80_12745	COG0542	response to heat
GET80_12750	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
GET80_12755	COG1278	Cold shock
GET80_12760	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
GET80_12840	COG3829	transcription factor binding
GET80_12915	COG3501	Rhs element vgr protein
GET80_12945	COG1435	thymidine kinase activity
GET80_12950	COG1757	Na H antiporter
GET80_12955	COG2916	Histone family protein nucleoid-structuring protein H-NS
GET80_12960	COG2096	Adenosyltransferase
GET80_12965	COG3530	Putative quorum-sensing-regulated virulence factor
GET80_12970	COG0602	queuosine metabolic process
GET80_12975	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
GET80_12995	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
GET80_13005	COG0776	regulation of translation
GET80_13010	COG0539	negative regulation of cytoplasmic translation
GET80_13015	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
GET80_13020	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
GET80_13030	COG0583	DNA-binding transcription factor activity
GET80_13050	COG0778	Nitroreductase
GET80_13055	COG3300	MHYT domain
GET80_13055	COG5001	Diguanylate cyclase
GET80_13065	COG0583	DNA-binding transcription factor activity
GET80_13070	COG3437	response regulator, receiver
GET80_13095	COG4989	oxidoreductase activity
GET80_13100	COG0724	RNA recognition motif
GET80_13120	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
GET80_13135	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
GET80_13140	COG1360	Flagellar Motor Protein
GET80_13145	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
GET80_13150	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
GET80_13155	COG0649	NAD binding
GET80_13155	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
GET80_13170	COG1034	ATP synthesis coupled electron transport
GET80_13175	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
GET80_13180	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
GET80_13185	COG0839	Belongs to the complex I subunit 6 family
GET80_13190	COG0713	ATP synthesis coupled electron transport
GET80_13200	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
GET80_13205	COG1007	ATP synthesis coupled electron transport
GET80_13220	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
GET80_13220	COG2199	diguanylate cyclase activity
GET80_13225	COG0047	phosphoribosylformylglycinamidine synthase activity
GET80_13225	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
GET80_13230	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
GET80_13240	COG1645	bacterial-type flagellum-dependent swarming motility
GET80_13245	COG1160	GTP binding
GET80_13250	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
GET80_13255	COG2976	Protein conserved in bacteria
GET80_13260	COG0124	histidyl-tRNA synthetase
GET80_13265	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
GET80_13270	COG1426	Protein conserved in bacteria
GET80_13280	COG0820	rRNA (adenine-C2-)-methyltransferase activity
GET80_13285	COG0105	UTP biosynthetic process
GET80_13290	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
GET80_13300	COG0633	Ferredoxin
GET80_13305	COG0443	Heat shock 70 kDa protein
GET80_13310	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
GET80_13320	COG0822	iron-sulfur transferase activity
GET80_13325	COG1104	cysteine desulfurase activity
GET80_13345	COG3154	lipid carrier protein
GET80_13350	COG0826	peptidase U32
GET80_13355	COG0826	peptidase U32
GET80_13370	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
GET80_13375	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
GET80_13380	COG1862	Preprotein translocase
GET80_13385	COG0343	queuine tRNA-ribosyltransferase activity
GET80_13390	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
GET80_13395	COG0517	IMP dehydrogenase activity
GET80_13405	COG3634	alkyl hydroperoxide reductase activity
GET80_13425	COG1393	Belongs to the ArsC family
GET80_13430	COG0798	PFAM Bile acid sodium symporter
GET80_13460	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
GET80_13460	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
GET80_13465	COG0509	glycine decarboxylation via glycine cleavage system
GET80_13470	COG0404	The glycine cleavage system catalyzes the degradation of glycine
GET80_13475	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
GET80_13480	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
GET80_13500	COG2814	Major facilitator Superfamily
GET80_13505	COG0625	glutathione transferase activity
GET80_13515	COG0483	inositol monophosphate 1-phosphatase activity
GET80_13535	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
GET80_13580	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
GET80_13600	COG0301	tRNA thio-modification
GET80_13600	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
GET80_13610	COG4953	penicillin-binding protein 1C
GET80_13615	COG2373	Large extracellular alpha-helical protein
GET80_13620	COG0446	pyridine nucleotide-disulphide oxidoreductase
GET80_13630	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
GET80_13675	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
GET80_13695	COG1216	Glycosyl transferase, family 2
GET80_13720	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GET80_13730	COG2431	L-lysine efflux transmembrane transporter activity
GET80_13735	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
GET80_13740	COG3124	Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP
GET80_13755	COG1393	Belongs to the ArsC family
GET80_13765	COG4783	chaperone-mediated protein folding
GET80_13770	COG0425	Belongs to the sulfur carrier protein TusA family
GET80_13785	COG2326	polyphosphate kinase activity
GET80_13790	COG3842	ATPase activity
GET80_13795	COG3833	ABC-type maltose transport systems, permease component
GET80_13800	COG1175	transmembrane transport
GET80_13810	COG3081	Nucleoid-associated protein
GET80_13815	COG3082	Protein of unknown function (DUF1414)
GET80_13820	COG3083	sulfuric ester hydrolase activity
GET80_13825	COG4771	TonB-dependent receptor
GET80_13830	COG1770	oligopeptidase
GET80_13850	COG4574	serine-type endopeptidase inhibitor activity
GET80_13855	COG3085	chromosome segregation
GET80_13860	COG0583	DNA-binding transcription factor activity
GET80_13865	COG0287	Prephenate dehydrogenase
GET80_13865	COG1605	Chorismate mutase
GET80_13870	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
GET80_13875	COG0584	glycerophosphoryl diester phosphodiesterase
GET80_13885	COG1349	DNA-binding transcription factor activity
GET80_13890	COG2271	Major facilitator Superfamily
GET80_13895	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
GET80_13900	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
GET80_13905	COG0583	DNA-binding transcription factor activity
GET80_13930	COG0656	L-ascorbic acid biosynthetic process
GET80_13935	COG2814	Major facilitator Superfamily
GET80_13945	COG1294	oxidase, subunit
GET80_13955	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GET80_13960	COG2979	Protein of unknown function (DUF533)
GET80_13985	COG2271	Major facilitator Superfamily
GET80_14000	COG2807	transmembrane transport
GET80_14010	COG1187	pseudouridine synthase activity
GET80_14030	COG0346	lactoylglutathione lyase activity
GET80_14040	COG1403	HNH endonuclease
GET80_14050	COG2964	Protein conserved in bacteria
GET80_14055	COG3681	Belongs to the UPF0597 family
GET80_14065	COG0814	amino acid
GET80_14085	COG1166	arginine decarboxylase activity
GET80_14105	COG2195	Cleaves the N-terminal amino acid of tripeptides
GET80_14135	COG0583	DNA-binding transcription factor activity
GET80_14145	COG2759	Belongs to the formate--tetrahydrofolate ligase family
GET80_14150	COG2759	Belongs to the formate--tetrahydrofolate ligase family
GET80_14155	COG0840	transmembrane signaling receptor activity
GET80_14160	COG0302	gtp cyclohydrolase
GET80_14170	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
GET80_14175	COG2267	carboxylic ester hydrolase activity
GET80_14180	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
GET80_14195	COG0314	molybdopterin synthase activity
GET80_14200	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
GET80_14205	COG0315	cyclic pyranopterin monophosphate synthase activity
GET80_14210	COG0521	Mo-molybdopterin cofactor biosynthetic process
GET80_14215	COG3005	denitrification pathway
GET80_14225	COG0348	domain, Protein
GET80_14230	COG0437	4 iron, 4 sulfur cluster binding
GET80_14235	COG0243	molybdopterin cofactor binding
GET80_14245	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
GET80_14245	COG1149	4fe-4S ferredoxin, iron-sulfur binding domain protein
GET80_14250	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
GET80_14255	COG3850	Histidine kinase
GET80_14260	COG2197	response regulator
GET80_14290	COG0121	glutamine amidotransferase
GET80_14295	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
GET80_14300	COG1960	acyl-CoA dehydrogenase activity
GET80_14305	COG3437	response regulator, receiver
GET80_14305	COG0784	Response regulator, receiver
GET80_14320	COG0328	RNA-DNA hybrid ribonuclease activity
GET80_14325	COG2226	methyltransferase
GET80_14330	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GET80_14335	COG1388	LysM domain
GET80_14335	COG0741	lytic transglycosylase activity
GET80_14340	COG3021	interspecies interaction between organisms
GET80_14350	COG1607	acyl-coa hydrolase
GET80_14365	COG0741	lytic transglycosylase activity
GET80_14375	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
GET80_14400	COG0729	surface antigen
GET80_14410	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
GET80_14415	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
GET80_14425	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
GET80_14435	COG4134	Bacterial extracellular solute-binding protein
GET80_14445	COG4136	ATPase activity
GET80_14450	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
GET80_14455	COG2951	lytic endotransglycosylase activity
GET80_14470	COG1846	Transcriptional regulator
GET80_14480	COG0033	Phosphoglucomutase
GET80_14485	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
GET80_14490	COG0596	Alpha beta hydrolase
GET80_14505	COG0716	FMN binding
GET80_14515	COG0735	belongs to the Fur family
GET80_14520	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
GET80_14530	COG2190	(PTS) system
GET80_14530	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GET80_14530	COG1263	PTS System
GET80_14535	COG0363	glucosamine-6-phosphate deaminase activity
GET80_14540	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
GET80_14545	COG1940	carbohydrate kinase activity
GET80_14545	COG1846	Transcriptional regulator
GET80_14550	COG2194	sulfuric ester hydrolase activity
GET80_14555	COG0217	transcriptional regulatory protein
GET80_14560	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
GET80_14570	COG1801	Protein of unknown function DUF72
GET80_14575	COG4106	trans-aconitate 2-methyltransferase activity
GET80_14580	COG0500	methyltransferase
GET80_14600	COG0450	alkyl hydroperoxide reductase
GET80_14605	COG0583	DNA-binding transcription factor activity
GET80_14615	COG0791	NLP P60 protein
GET80_14630	COG1309	transcriptional regulator
GET80_14670	COG0534	Mate efflux family protein
GET80_14690	COG0674	pyruvate-flavodoxin oxidoreductase activity
GET80_14690	COG1013	pyruvate-flavodoxin oxidoreductase activity
GET80_14690	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
GET80_14690	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
GET80_14700	COG0633	Ferredoxin
GET80_14700	COG3217	Mosc domain protein beta barrel domain protein
GET80_14700	COG3217	Mosc domain protein beta barrel domain protein
GET80_14700	COG0633	Ferredoxin
GET80_14710	COG0501	Belongs to the peptidase M48B family
GET80_14715	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
GET80_14720	COG2226	methyltransferase
GET80_14720	COG1073	alpha beta
GET80_14725	COG0156	8-amino-7-oxononanoate synthase activity
GET80_14730	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
GET80_14750	COG0017	Asparaginyl-tRNA synthetase
GET80_14755	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
GET80_14770	COG3069	C4-dicarboxylate transmembrane transporter activity
GET80_14780	COG0583	DNA-binding transcription factor activity
GET80_14785	COG1393	Belongs to the ArsC family
GET80_14790	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
GET80_14795	COG1876	peptidase activity
GET80_14805	COG3263	regulation of cellular component size
GET80_14825	COG1280	lysine exporter protein (LysE YggA)
GET80_14865	COG1454	alcohol dehydrogenase
GET80_14870	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
GET80_14875	COG0702	epimerase
GET80_14880	COG2914	Belongs to the UPF0125 (RnfH) family
GET80_14885	COG2867	negative regulation of translational initiation
GET80_14890	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
GET80_14910	COG0732	type I restriction modification DNA specificity domain
GET80_14940	COG0583	DNA-binding transcription factor activity
GET80_14950	COG3048	D-serine ammonia-lyase activity
GET80_14960	COG0538	isocitrate dehydrogenase activity
GET80_14965	COG2207	Transcriptional regulator
GET80_14970	COG1482	cell wall glycoprotein biosynthetic process
GET80_14985	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GET80_15000	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
GET80_15005	COG1263	PTS System
GET80_15005	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GET80_15010	COG1609	Transcriptional regulator
GET80_15015	COG0446	pyridine nucleotide-disulphide oxidoreductase
GET80_15015	COG1902	pentaerythritol trinitrate reductase activity
GET80_15020	COG0789	Transcriptional regulator
GET80_15030	COG0456	acetyltransferase
GET80_15040	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GET80_15040	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
GET80_15040	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GET80_15050	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GET80_15050	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GET80_15050	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
GET80_15060	COG1187	pseudouridine synthase activity
GET80_15070	COG0482	sulfurtransferase activity
GET80_15075	COG2915	High frequency lysogenization protein hflD homolog
GET80_15080	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
GET80_15085	COG2850	peptidyl-arginine hydroxylation
GET80_15095	COG3153	acetyltransferase
GET80_15105	COG0625	glutathione transferase activity
GET80_15110	COG0259	pyridoxamine-phosphate oxidase activity
GET80_15125	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
GET80_15125	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
GET80_15130	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
GET80_15145	COG3088	subunit of a heme lyase
GET80_15145	COG4235	cytochrome complex assembly
GET80_15150	COG3088	subunit of a heme lyase
GET80_15150	COG4235	cytochrome complex assembly
GET80_15155	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GET80_15160	COG1138	Cytochrome C-type biogenesis protein
GET80_15165	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
GET80_15170	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
GET80_15175	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
GET80_15180	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
GET80_15195	COG0835	chemotaxis
GET80_15205	COG1192	Involved in chromosome partitioning
GET80_15210	COG1360	Flagellar Motor Protein
GET80_15215	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
GET80_15220	COG2201	protein-glutamate methylesterase activity
GET80_15225	COG0643	Histidine kinase
GET80_15225	COG0784	Response regulator, receiver
GET80_15225	COG2198	Histidine kinase
GET80_15230	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
GET80_15255	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
GET80_15265	COG1684	flagellar biosynthetic protein fliR
GET80_15320	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
GET80_15330	COG1677	Flagellar hook-basal body complex protein FliE
GET80_15345	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
GET80_15355	COG3064	Membrane
GET80_15355	COG1073	alpha beta
GET80_15355	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
GET80_15360	COG2994	toxin metabolic process
GET80_15370	COG2274	protein secretion by the type I secretion system
GET80_15380	COG2274	protein secretion by the type I secretion system
GET80_15400	COG1737	Transcriptional regulator
GET80_15405	COG0469	pyruvate kinase activity
GET80_15415	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
GET80_15420	COG1960	acyl-CoA dehydrogenase activity
GET80_15430	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
GET80_15465	COG0243	molybdopterin cofactor binding
GET80_15470	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
GET80_15475	COG0583	DNA-binding transcription factor activity
GET80_15510	COG1012	belongs to the aldehyde dehydrogenase family
GET80_15510	COG1454	alcohol dehydrogenase
GET80_15520	COG1454	alcohol dehydrogenase
GET80_15520	COG1012	belongs to the aldehyde dehydrogenase family
GET80_15525	COG1882	Formate acetyltransferase
GET80_15530	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
GET80_15540	COG4869	propanediol catabolic process
GET80_15580	COG4409	exo-alpha-(2->6)-sialidase activity
GET80_15585	COG2731	YhcH YjgK YiaL family protein
GET80_15590	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GET80_15600	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
GET80_15605	COG1737	Transcriptional regulator
GET80_15610	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
GET80_15615	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
GET80_15620	COG1349	DNA-binding transcription factor activity
GET80_15625	COG0738	Major facilitator superfamily
GET80_15635	COG1070	Carbohydrate kinase
GET80_15655	COG4172	Belongs to the ABC transporter superfamily
GET80_15660	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GET80_15670	COG0747	negative chemotaxis
GET80_15685	COG1376	ErfK ybiS ycfS ynhG family protein
GET80_15685	COG1388	LysM domain
GET80_15700	COG3129	Specifically methylates the adenine in position 1618 of 23S rRNA
GET80_15705	COG0791	NLP P60 protein
GET80_15710	COG2091	lysine biosynthetic process via aminoadipic acid
GET80_15715	COG3118	belongs to the thioredoxin family
GET80_15725	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
GET80_15730	COG0788	formyltetrahydrofolate deformylase activity
GET80_15740	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
GET80_15760	COG0366	Alpha amylase catalytic
GET80_15765	COG0739	heme binding
GET80_15765	COG0741	lytic transglycosylase activity
GET80_15765	COG1196	nuclear chromosome segregation
GET80_15770	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
GET80_15775	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
GET80_15785	COG0673	inositol 2-dehydrogenase activity
GET80_15820	COG1032	radical SAM domain protein
GET80_15830	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
GET80_15835	COG1566	PFAM secretion protein HlyD family protein
GET80_15840	COG2199	diguanylate cyclase activity
GET80_15840	COG2203	Gaf domain
GET80_15845	COG1752	Esterase of the alpha-beta hydrolase superfamily
GET80_15850	COG0733	neurotransmitter:sodium symporter activity
GET80_15880	COG0281	malic enzyme
GET80_15890	COG0534	Mate efflux family protein
GET80_15905	COG2233	PERMEase
GET80_15910	COG0095	Lipoate-protein ligase
GET80_15915	COG1115	amino acid carrier protein
GET80_15920	COG0019	diaminopimelate decarboxylase activity
GET80_15930	COG0678	peroxiredoxin activity
GET80_15940	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
GET80_15960	COG1131	(ABC) transporter
GET80_15965	COG0545	Peptidyl-prolyl cis-trans isomerase
GET80_15970	COG3142	Participates in the control of copper homeostasis
GET80_15995	COG5002	protein histidine kinase activity
GET80_16000	COG0745	RESPONSE REGULATOR receiver
GET80_16005	COG0346	lactoylglutathione lyase activity
GET80_16010	COG1804	L-carnitine dehydratase bile acid-inducible protein F
GET80_16015	COG1960	acyl-CoA dehydrogenase activity
GET80_16020	COG3284	Transcriptional regulator
GET80_16035	COG0697	spore germination
GET80_16040	COG4565	transcriptional regulatory protein
GET80_16045	COG3290	protein histidine kinase activity
GET80_16050	COG0281	malic enzyme
GET80_16070	COG1846	Transcriptional regulator
GET80_16075	COG1566	PFAM secretion protein HlyD family protein
GET80_16105	COG0602	queuosine metabolic process
GET80_16120	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
GET80_16125	COG3115	cell septum assembly
GET80_16130	COG1196	nuclear chromosome segregation
GET80_16140	COG2860	membrane
GET80_16150	COG3108	Peptidase M15
GET80_16155	COG2989	Protein conserved in bacteria
GET80_16170	COG0463	Glycosyl transferase, family 2
GET80_16185	COG0366	Alpha amylase catalytic
GET80_16220	COG3706	GGDEF domain
GET80_16230	COG3590	peptidase
GET80_16240	COG0488	(ABC) transporter
GET80_16250	COG0531	amino acid
GET80_16260	COG1073	alpha beta
GET80_16265	COG1073	alpha beta
GET80_16275	COG1234	tRNA 3'-trailer cleavage
GET80_16280	COG0814	amino acid
GET80_16295	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
GET80_16300	COG1982	Orn Lys Arg decarboxylase major
GET80_16305	COG0531	amino acid
GET80_16310	COG3710	Transcriptional regulator
GET80_16315	COG0825	malonyl-CoA metabolic process
GET80_16325	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
GET80_16330	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
GET80_16335	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
GET80_16340	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
GET80_16345	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
GET80_16360	COG0750	zinc metalloprotease
GET80_16365	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
GET80_16370	COG0575	Belongs to the CDS family
GET80_16375	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
GET80_16380	COG0233	cytoplasmic translational termination
GET80_16385	COG0528	UMP kinase activity
GET80_16390	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
GET80_16395	COG0052	Belongs to the universal ribosomal protein uS2 family
GET80_16400	COG0024	Methionine aminopeptidase
GET80_16405	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
GET80_16410	COG2171	N-acyltransferase activity
GET80_16420	COG1263	PTS System
GET80_16420	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GET80_16430	COG4580	involved in the transport of maltose and maltodextrins
GET80_16440	COG0564	pseudouridine synthase activity
GET80_16445	COG3098	single-species biofilm formation
GET80_16470	COG5595	Zn-ribbon-containing, possibly nucleic-acid-binding protein (DUF2310)
GET80_16480	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
GET80_16480	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
GET80_16495	COG1611	Belongs to the LOG family
GET80_16500	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
GET80_16505	COG0473	3-isopropylmalate dehydrogenase activity
GET80_16515	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
GET80_16520	COG2363	Small membrane protein
GET80_16530	COG0583	DNA-binding transcription factor activity
GET80_16535	COG0840	transmembrane signaling receptor activity
GET80_16540	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
GET80_16555	COG1477	protein flavinylation
GET80_16560	COG2871	sodium ion transport
GET80_16565	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
GET80_16570	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
GET80_16575	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
GET80_16580	COG1805	sodium ion transport
GET80_16585	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
GET80_16590	COG0271	Belongs to the BolA IbaG family
GET80_16595	COG2813	Specifically methylates the guanine in position
GET80_16605	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
GET80_16615	COG2211	Major facilitator Superfamily
GET80_16620	COG3248	Nucleoside-binding outer membrane protein
GET80_16625	COG1666	GTP binding
GET80_16630	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
GET80_16635	COG0693	protein deglycase activity
GET80_16670	COG3501	Rhs element vgr protein
GET80_16685	COG2771	luxR family
GET80_16700	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
GET80_16700	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
GET80_16705	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
GET80_16715	COG1151	hydroxylamine reductase activity
GET80_16720	COG0783	Belongs to the Dps family
GET80_16745	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
GET80_16760	COG4221	oxidoreductase activity
GET80_16770	COG0415	Belongs to the DNA photolyase family
GET80_16775	COG0789	Transcriptional regulator
GET80_16780	COG3272	Protein of unknown function (DUF1722)
GET80_16810	COG0077	Prephenate dehydratase
GET80_16810	COG1605	Chorismate mutase
GET80_16835	COG3254	rhamnose metabolic process
GET80_16845	COG4806	L-rhamnose isomerase
GET80_16850	COG1070	Carbohydrate kinase
GET80_16855	COG4977	sequence-specific DNA binding
GET80_16860	COG1454	alcohol dehydrogenase
GET80_16865	COG0235	Class ii aldolase
GET80_16875	COG0840	transmembrane signaling receptor activity
GET80_16885	COG0300	oxidoreductase activity
GET80_16910	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
GET80_16940	COG0826	peptidase U32
GET80_16945	COG1280	lysine exporter protein (LysE YggA)
GET80_16955	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
GET80_16960	COG0840	transmembrane signaling receptor activity
GET80_16975	COG0643	Histidine kinase
GET80_16975	COG2198	Histidine kinase
GET80_16985	COG0835	chemotaxis
GET80_16990	COG0840	transmembrane signaling receptor activity
GET80_17000	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
GET80_17005	COG2201	protein-glutamate methylesterase activity
GET80_17010	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
GET80_17040	COG2197	response regulator
GET80_17050	COG3188	usher protein
GET80_17065	COG2199	diguanylate cyclase activity
GET80_17065	COG2200	EAL domain
GET80_17065	COG2203	Gaf domain
GET80_17070	COG0826	peptidase U32
GET80_17075	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
GET80_17085	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
GET80_17095	COG0305	Participates in initiation and elongation during chromosome replication
GET80_17110	COG2200	EAL domain
GET80_17115	COG0737	Belongs to the 5'-nucleotidase family
GET80_17135	COG2204	response regulator
GET80_17140	COG0545	Peptidyl-prolyl cis-trans isomerase
GET80_17155	COG1047	Peptidyl-prolyl cis-trans
GET80_17160	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
GET80_17170	COG0835	chemotaxis
GET80_17170	COG0784	Response regulator, receiver
GET80_17175	COG0429	hydrolase of the alpha beta-hydrolase fold
GET80_17180	COG2203	Gaf domain
GET80_17180	COG3706	GGDEF domain
GET80_17180	COG4251	negative regulation of phosphorylation
GET80_17180	COG5001	Diguanylate cyclase
GET80_17185	COG3089	Belongs to the UPF0270 family
GET80_17195	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
GET80_17200	COG0463	Glycosyl transferase, family 2
GET80_17205	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
GET80_17205	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GET80_17210	COG0726	polysaccharide deacetylase
GET80_17215	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
GET80_17220	COG2076	Multidrug Resistance protein
GET80_17225	COG2076	Multidrug Resistance protein
GET80_17230	COG3954	Phosphoribulokinase
GET80_17245	COG1765	OsmC-like protein
GET80_17255	COG2226	methyltransferase
GET80_17260	COG3397	chitin binding
GET80_17275	COG2202	Pas domain
GET80_17275	COG2205	protein histidine kinase activity
GET80_17285	COG3655	Transcriptional regulator
GET80_17290	COG2814	Major facilitator Superfamily
GET80_17295	COG4771	TonB-dependent receptor
GET80_17315	COG0748	coenzyme F420 binding
GET80_17320	COG3721	Heme iron utilization protein
GET80_17330	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GET80_17355	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
GET80_17360	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
GET80_17365	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
GET80_17385	COG0741	lytic transglycosylase activity
GET80_17390	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
GET80_17405	COG0488	(ABC) transporter
GET80_17415	COG2252	PERMEase
GET80_17420	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
GET80_17425	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
GET80_17430	COG3178	'Phosphotransferase
GET80_17435	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
GET80_17445	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
GET80_17450	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
GET80_17455	COG2967	ApaG domain
GET80_17460	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
GET80_17470	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GET80_17475	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
GET80_17490	COG0318	PFAM AMP-dependent synthetase and ligase
GET80_17495	COG3314	Sporulation integral membrane protein YlbJ
GET80_17500	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
GET80_17505	COG0211	Belongs to the bacterial ribosomal protein bL27 family
GET80_17510	COG0261	This protein binds to 23S rRNA in the presence of protein L20
GET80_17515	COG0142	geranyltranstransferase activity
GET80_17520	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
GET80_17525	COG0330	HflC and HflK could
GET80_17530	COG0330	HflC and HflK could
GET80_17535	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
GET80_17540	COG1923	regulation of RNA biosynthetic process
GET80_17545	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
GET80_17550	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
GET80_17560	COG0802	atpase or kinase
GET80_17565	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
GET80_17565	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
GET80_17585	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
GET80_17590	COG2011	ABC-type metal ion transport system permease component
GET80_17595	COG1464	Belongs to the NlpA lipoprotein family
GET80_17615	COG0840	transmembrane signaling receptor activity
GET80_17640	COG0784	Response regulator, receiver
GET80_17640	COG2198	Histidine kinase
GET80_17640	COG5002	protein histidine kinase activity
GET80_17660	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
GET80_17675	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
GET80_17680	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
GET80_17690	COG2716	regulation of RNA biosynthetic process
GET80_17695	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
GET80_17700	COG3013	Belongs to the UPF0304 family
GET80_17710	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
GET80_17715	COG0857	belongs to the CobB CobQ family
GET80_17715	COG0280	phosphate acetyltransferase
GET80_17725	COG0028	Belongs to the TPP enzyme family
GET80_17735	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
GET80_17740	COG0671	phosphoesterase, PA-phosphatase related
GET80_17750	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
GET80_17755	COG0473	3-isopropylmalate dehydrogenase activity
GET80_17760	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
GET80_17765	COG0066	3-isopropylmalate dehydratase activity
GET80_17785	COG1178	ABC-type Fe3 transport system permease component
GET80_17790	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
GET80_17795	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
GET80_17835	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
GET80_17840	COG0564	pseudouridine synthase activity
GET80_17850	COG3300	MHYT domain
GET80_17850	COG5001	Diguanylate cyclase
GET80_17860	COG0459	protein refolding
GET80_17865	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
GET80_17870	COG0534	Mate efflux family protein
GET80_17875	COG3030	protein affecting phage T7 exclusion by the F plasmid
GET80_17880	COG1027	Aspartate ammonia-lyase
GET80_17885	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
GET80_17895	COG0477	Major facilitator Superfamily
GET80_17910	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GET80_17915	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GET80_17925	COG0673	inositol 2-dehydrogenase activity
GET80_17935	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
GET80_17940	COG0635	Involved in the biosynthesis of porphyrin-containing compound
GET80_17945	COG3036	rescue of stalled ribosome
GET80_17950	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
GET80_17960	COG0138	bifunctional purine biosynthesis protein purh
GET80_17965	COG0151	Belongs to the GarS family
GET80_17990	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
GET80_17995	COG0358	DNA primase activity
GET80_18000	COG1610	YqeY-like protein
GET80_18005	COG0828	Belongs to the bacterial ribosomal protein bS21 family
GET80_18010	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
GET80_18025	COG1238	metal cluster binding
GET80_18030	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
GET80_18035	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
GET80_18040	COG0585	pseudouridine synthase activity
GET80_18050	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
GET80_18055	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
GET80_18060	COG0148	phosphopyruvate hydratase activity
GET80_18065	COG0504	CTP synthase activity
GET80_18070	COG3956	TIGRFAM MazG family protein
GET80_18075	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
GET80_18080	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
GET80_18090	COG4807	Protein conserved in bacteria
GET80_18095	COG3023	N-Acetylmuramoyl-L-alanine amidase
GET80_18100	COG1349	DNA-binding transcription factor activity
GET80_18110	COG2222	sugar isomerase
GET80_18115	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GET80_18125	COG3716	PTS system mannose fructose sorbose family IID component
GET80_18130	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
GET80_18135	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
GET80_18150	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
GET80_18155	COG1381	Involved in DNA repair and RecF pathway recombination
GET80_18165	COG0571	ribonuclease III activity
GET80_18170	COG0681	Belongs to the peptidase S26 family
GET80_18175	COG0481	GTPase activity
GET80_18190	COG3073	An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E
GET80_18195	COG1595	DNA-templated transcription, initiation
GET80_18200	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
GET80_18210	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
GET80_18250	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
GET80_18260	COG0126	phosphoglycerate kinase activity
GET80_18265	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
GET80_18270	COG1940	carbohydrate kinase activity
GET80_18275	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
GET80_18290	COG4991	sh3 domain protein
GET80_18295	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
GET80_18310	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
GET80_18315	COG1028	Short-chain dehydrogenase reductase Sdr
GET80_18335	COG1505	serine-type exopeptidase activity
GET80_18340	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
GET80_18345	COG0765	amino acid transport
GET80_18350	COG0765	amino acid transport
GET80_18355	COG1126	abc transporter atp-binding protein
GET80_18360	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GET80_18365	COG0577	efflux transmembrane transporter activity
GET80_18365	COG1136	(ABC) transporter
GET80_18370	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GET80_18375	COG0745	RESPONSE REGULATOR receiver
GET80_18380	COG2205	protein histidine kinase activity
GET80_18385	COG2816	NAD+ diphosphatase activity
GET80_18415	COG2070	2-Nitropropane dioxygenase
GET80_18445	COG1912	Pfam S-adenosyl-l-methionine hydroxide adenosyltransferase
GET80_18465	COG0513	Belongs to the DEAD box helicase family
GET80_18490	COG0154	amidase activity
GET80_18495	COG2957	Belongs to the agmatine deiminase family
GET80_18510	COG1902	pentaerythritol trinitrate reductase activity
GET80_18550	COG5001	Diguanylate cyclase
GET80_18550	COG3300	MHYT domain
GET80_18560	COG0714	Associated with various cellular activities
GET80_18570	COG0456	acetyltransferase
GET80_18580	COG1022	Amp-dependent synthetase and ligase
GET80_18590	COG2918	glutathione biosynthetic process
GET80_18595	COG0612	Peptidase, M16
GET80_18600	COG1238	metal cluster binding
GET80_18630	COG0359	binds to the 23S rRNA
GET80_18635	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
GET80_18640	COG0360	Binds together with S18 to 16S ribosomal RNA
GET80_18645	COG1914	H( )-stimulated, divalent metal cation uptake system
GET80_18650	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
GET80_18665	COG2153	protein acetylation
GET80_18675	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
GET80_18680	COG0557	exoribonuclease II activity
GET80_18685	COG3706	GGDEF domain
GET80_18690	COG1854	S-ribosylhomocysteine lyase activity
GET80_18705	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
GET80_18705	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
GET80_18765	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
GET80_18770	COG1047	Peptidyl-prolyl cis-trans
GET80_18775	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
GET80_18780	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
GET80_18785	COG0196	riboflavin kinase activity
GET80_18790	COG0728	peptidoglycan biosynthetic process
GET80_18795	COG0268	Binds directly to 16S ribosomal RNA
GET80_18800	COG0640	Transcriptional regulator
GET80_18805	COG0583	DNA-binding transcription factor activity
GET80_18815	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
GET80_18820	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
GET80_18825	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
GET80_18835	COG1051	belongs to the nudix hydrolase family
GET80_18840	COG3066	DNA modification
GET80_18850	COG0335	large ribosomal subunit rRNA binding
GET80_18855	COG0336	Belongs to the RNA methyltransferase TrmD family
GET80_18860	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
GET80_18865	COG0228	four-way junction DNA binding
GET80_18870	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
GET80_18875	COG4137	Cytochrome C assembly protein
GET80_18880	COG4536	flavin adenine dinucleotide binding
GET80_18890	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
GET80_18890	COG1017	nitric oxide dioxygenase activity
GET80_18895	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
GET80_18900	COG0039	L-malate dehydrogenase activity
GET80_18905	COG4160	amino acid transport
GET80_18910	COG4215	(ABC) transporter
GET80_18915	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GET80_18920	COG1126	abc transporter atp-binding protein
GET80_18925	COG1438	arginine binding
GET80_18930	COG2837	iron assimilation
GET80_18935	COG3842	ATPase activity
GET80_18945	COG1840	ABC-type Fe3 transport system, periplasmic component
GET80_18950	COG0347	Belongs to the P(II) protein family
GET80_18965	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
GET80_18970	COG0583	DNA-binding transcription factor activity
GET80_18985	COG1929	Belongs to the glycerate kinase type-1 family
GET80_18990	COG2610	gluconate transmembrane transporter activity
GET80_18995	COG3835	regulator
GET80_19000	COG3112	Uncharacterised protein family (UPF0231)
GET80_19015	COG0840	transmembrane signaling receptor activity
GET80_19035	COG0513	Belongs to the DEAD box helicase family
GET80_19075	COG1448	Aminotransferase
GET80_19090	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
GET80_19095	COG1328	CTP reductase activity
GET80_19115	COG0793	Belongs to the peptidase S41A family
GET80_19115	COG4946	Tricorn protease homolog
GET80_19155	COG3397	chitin binding
GET80_19160	COG0583	DNA-binding transcription factor activity
GET80_19165	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
GET80_19170	COG4208	sulfate ABC transporter
GET80_19175	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
GET80_19185	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
GET80_19190	COG3174	membrane
GET80_19195	COG0110	maltose O-acetyltransferase activity
GET80_19220	COG0165	Argininosuccinate lyase
GET80_19225	COG0137	argininosuccinate synthase activity
GET80_19235	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
GET80_19240	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
GET80_19250	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
GET80_19265	COG0527	aspartate kinase activity
GET80_19265	COG0460	homoserine dehydrogenase
GET80_19270	COG0626	cystathionine gamma-synthase activity
GET80_19280	COG3708	Transcriptional regulator
GET80_19280	COG2207	Transcriptional regulator
GET80_19285	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GET80_19290	COG0814	amino acid
GET80_19295	COG1218	3'(2'),5'-bisphosphate nucleotidase
GET80_19300	COG0494	nUDIX hydrolase
GET80_19305	COG1011	Hydrolase
GET80_19310	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
GET80_19325	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
GET80_19335	COG3156	type II secretion system protein K
GET80_19345	COG4795	General secretion pathway protein
GET80_19350	COG2165	general secretion pathway protein
GET80_19365	COG2165	general secretion pathway protein
GET80_19370	COG1459	type II secretion system
GET80_19375	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
GET80_19385	COG3031	protein transport across the cell outer membrane
GET80_19395	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
GET80_19400	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
GET80_19420	COG0456	acetyltransferase
GET80_19425	COG3133	Outer membrane lipoprotein
GET80_19440	COG2771	luxR family
GET80_19445	COG3916	Acyl-homoserine-lactone synthase
GET80_19455	COG4776	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction
GET80_19460	COG1309	transcriptional regulator
GET80_19470	COG2213	PTS system mannitol-specific
GET80_19470	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
GET80_19475	COG0246	Mannitol dehydrogenase
GET80_19480	COG3722	fumarate hydratase activity
GET80_19485	COG3263	regulation of cellular component size
GET80_19510	COG1671	Belongs to the UPF0178 family
GET80_19525	COG1988	membrane-bound metal-dependent
GET80_19530	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
GET80_19535	COG0513	Belongs to the DEAD box helicase family
GET80_19560	COG1575	Belongs to the MenA family. Type 1 subfamily
GET80_19565	COG1169	isochorismate synthase
GET80_19570	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
GET80_19575	COG0596	Alpha beta hydrolase
GET80_19580	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
GET80_19585	COG1441	menaquinone biosynthetic process
GET80_19590	COG0318	PFAM AMP-dependent synthetase and ligase
GET80_19605	COG3539	Fimbrial protein
GET80_19610	COG3121	Chaperone
GET80_19615	COG3188	usher protein
GET80_19625	COG3539	Fimbrial protein
GET80_19635	COG3291	Pkd domain containing protein
GET80_19640	COG2949	membrane
GET80_19645	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
GET80_19660	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
GET80_19665	COG5380	lipid catabolic process
GET80_19680	COG4533	DNA binding
GET80_19690	COG2873	o-acetylhomoserine
GET80_19700	COG1979	alcohol dehydrogenase
GET80_19720	COG4221	oxidoreductase activity
GET80_19740	COG1285	pathogenesis
GET80_19760	COG1368	sulfuric ester hydrolase activity
GET80_19765	COG1522	sequence-specific DNA binding
GET80_19775	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
GET80_19780	COG1418	mRNA catabolic process
GET80_19785	COG1058	Belongs to the CinA family
GET80_19785	COG1546	Belongs to the CinA family
GET80_19795	COG0842	Transport permease protein
GET80_19795	COG1129	ABC transporter
GET80_19810	COG0561	phosphatase activity
GET80_19815	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
GET80_19835	COG1011	Hydrolase
GET80_19850	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
GET80_19855	COG0019	diaminopimelate decarboxylase activity
GET80_19865	COG1965	Belongs to the frataxin family
GET80_19870	COG0400	carboxylic ester hydrolase activity
GET80_19875	COG3072	Adenylate cyclase
GET80_19880	COG0181	hydroxymethylbilane synthase activity
GET80_19890	COG2959	enzyme of heme biosynthesis
GET80_19905	COG1494	fructose-1,6-bisphosphatase
GET80_19945	COG1733	regulation of RNA biosynthetic process
GET80_19965	COG3932	Exopolysaccharide synthesis, ExoD
GET80_19970	COG0814	amino acid
GET80_19990	COG3417	Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1B (PBP1b)
GET80_19995	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GET80_20005	COG1943	Transposase
GET80_20010	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
GET80_20015	COG2022	thiamine diphosphate biosynthetic process
GET80_20025	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
GET80_20030	COG0352	thiamine-phosphate diphosphorylase activity
GET80_20035	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
GET80_20050	COG0745	RESPONSE REGULATOR receiver
GET80_20055	COG0642	Histidine kinase
GET80_20065	COG0189	ligase activity
GET80_20090	COG1639	'signal transduction protein
GET80_20100	COG2321	neutral zinc metallopeptidase
GET80_20105	COG3700	Belongs to the class B bacterial acid phosphatase family
GET80_20125	COG1366	Belongs to the anti-sigma-factor antagonist family
GET80_20130	COG2172	sigma factor antagonist activity
GET80_20135	COG2205	protein histidine kinase activity
GET80_20135	COG5002	protein histidine kinase activity
GET80_20135	COG0784	Response regulator, receiver
GET80_20140	COG3437	response regulator, receiver
GET80_20150	COG0477	Major facilitator Superfamily
GET80_20165	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
GET80_20170	COG1263	PTS System
GET80_20170	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GET80_20190	COG0312	modulator of DNA gyrase
GET80_20195	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
GET80_20210	COG3164	Protein of unknown function
GET80_20215	COG1530	ribonuclease E activity
GET80_20220	COG0424	maF-like protein
GET80_20225	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
GET80_20230	COG1792	Involved in formation and maintenance of cell shape
GET80_20235	COG1077	Cell shape determining protein MreB Mrl
GET80_20260	COG4968	Prepilin-type N-terminal cleavage methylation domain
GET80_20270	COG2165	general secretion pathway protein
GET80_20280	COG1459	type II secretion system
GET80_20285	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
GET80_20330	COG2199	diguanylate cyclase activity
GET80_20330	COG2200	EAL domain
GET80_20335	COG2200	EAL domain
GET80_20340	COG0387	Pfam Sodium calcium exchanger
GET80_20345	COG2986	histidine ammonia-lyase
GET80_20350	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
GET80_20355	COG0010	Belongs to the arginase family
GET80_20360	COG1228	amidohydrolase
GET80_20365	COG2188	Transcriptional regulator
GET80_20370	COG0288	reversible hydration of carbon dioxide
GET80_20380	COG2177	Part of the ABC transporter FtsEX involved in
GET80_20385	COG2884	Cell division ATP-binding protein ftsE
GET80_20390	COG0552	protein localization to endoplasmic reticulum
GET80_20395	COG0742	ribosomal rna small subunit methyltransferase
GET80_20420	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
GET80_20425	COG0741	lytic transglycosylase activity
GET80_20435	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
GET80_20445	COG2095	MarC family integral membrane protein
GET80_20455	COG1301	dicarboxylic acid transport
GET80_20480	COG3714	YhhN family
GET80_20505	COG1770	oligopeptidase
GET80_20520	COG4221	oxidoreductase activity
GET80_20525	COG0583	DNA-binding transcription factor activity
GET80_20530	COG2249	NAD(P)H dehydrogenase (quinone) activity
GET80_20585	COG0203	ribosomal protein L17
GET80_20590	COG0202	RNA polymerase activity
GET80_20595	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
GET80_20600	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
GET80_20605	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
GET80_20610	COG0257	Belongs to the bacterial ribosomal protein bL36 family
GET80_20615	COG0201	protein transport
GET80_20620	COG0200	Binds to the 23S rRNA
GET80_20625	COG1841	ribosomal large subunit assembly
GET80_20630	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
GET80_20635	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
GET80_20640	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
GET80_20645	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
GET80_20650	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
GET80_20655	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
GET80_20660	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
GET80_20665	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
GET80_20670	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
GET80_20675	COG0255	Belongs to the universal ribosomal protein uL29 family
GET80_20680	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
GET80_20685	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
GET80_20690	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
GET80_20695	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
GET80_20700	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
GET80_20705	COG0089	rRNA binding
GET80_20710	COG0088	Forms part of the polypeptide exit tunnel
GET80_20715	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
GET80_20720	COG0051	transcription antitermination factor activity, RNA binding
GET80_20740	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
GET80_20745	COG2183	response to ionizing radiation
GET80_20765	COG0596	Alpha beta hydrolase
GET80_20770	COG1040	competence protein
GET80_20775	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
GET80_20775	COG0316	Belongs to the HesB IscA family
GET80_20780	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
GET80_20785	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
GET80_20790	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
GET80_20795	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
GET80_20800	COG4942	peptidase
GET80_20810	COG1609	Transcriptional regulator
GET80_20815	COG0800	Aldolase
GET80_20820	COG0129	dihydroxy-acid dehydratase activity
GET80_20825	COG3265	gluconokinase activity
GET80_20830	COG2610	gluconate transmembrane transporter activity
GET80_20835	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
GET80_20840	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
GET80_20850	COG0456	acetyltransferase
GET80_20860	COG1490	D-aminoacyl-tRNA deacylase activity
GET80_20865	COG1295	ribonuclease BN
GET80_20870	COG1295	ribonuclease BN
GET80_20875	COG1217	gtp-binding protein TYPA
GET80_20880	COG0174	glutamine synthetase
GET80_20890	COG3852	Histidine kinase
GET80_20895	COG2204	response regulator
GET80_20900	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
GET80_20905	COG0635	Involved in the biosynthesis of porphyrin-containing compound
GET80_20915	COG3078	GTPase activator activity
GET80_20930	COG0218	Necessary for normal cell division and for the maintenance of normal septation
GET80_20940	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
GET80_20945	COG0408	coproporphyrinogen oxidase activity
GET80_20950	COG0009	L-threonylcarbamoyladenylate synthase
GET80_20960	COG0551	DNA topoisomerase type I activity
GET80_20965	COG2922	Belongs to the Smg family
GET80_20970	COG0758	DNA mediated transformation
GET80_20980	COG0242	peptide deformylase activity
GET80_20985	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
GET80_20990	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
GET80_20990	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
GET80_20995	COG0569	domain protein
GET80_21000	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
GET80_21005	COG1322	Protein conserved in bacteria
GET80_21025	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GET80_21030	COG0686	Belongs to the AlaDH PNT family
GET80_21035	COG0519	Catalyzes the synthesis of GMP from XMP
GET80_21035	COG0518	GMP synthase (glutamine-hydrolyzing) activity
GET80_21045	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
GET80_21050	COG1396	sequence-specific DNA binding
GET80_21055	COG1012	belongs to the aldehyde dehydrogenase family
GET80_21065	COG2962	Rard protein
GET80_21075	COG1280	lysine exporter protein (LysE YggA)
GET80_21085	COG0840	transmembrane signaling receptor activity
GET80_21090	COG2391	methyltransferase activity
GET80_21095	COG1280	lysine exporter protein (LysE YggA)
GET80_21160	COG0210	DNA helicase
GET80_21165	COG1744	ABC transporter substrate-binding protein PnrA-like
GET80_21170	COG3845	ABC transporter
GET80_21175	COG4603	Belongs to the binding-protein-dependent transport system permease family
GET80_21180	COG1079	Belongs to the binding-protein-dependent transport system permease family
GET80_21185	COG0583	DNA-binding transcription factor activity
GET80_21205	COG1262	PFAM Formylglycine-generating sulfatase enzyme
GET80_21210	COG0385	Bile acid
GET80_21215	COG0531	amino acid
GET80_21220	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GET80_21225	COG0531	amino acid
GET80_21230	COG2731	YhcH YjgK YiaL family protein
GET80_21235	COG3250	beta-galactosidase activity
GET80_21240	COG1609	Transcriptional regulator
GET80_21275	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
GET80_21280	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
GET80_21280	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
GET80_21285	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
GET80_21290	COG3074	FtsZ-dependent cytokinesis
GET80_21300	COG1045	serine acetyltransferase
GET80_21310	COG0745	RESPONSE REGULATOR receiver
GET80_21315	COG2205	protein histidine kinase activity
GET80_21320	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
GET80_21325	COG0534	Mate efflux family protein
GET80_21350	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
GET80_21355	COG2937	Belongs to the GPAT DAPAT family
GET80_21360	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
GET80_21365	COG3161	chorismate lyase activity
GET80_21370	COG1580	Controls the rotational direction of flagella during chemotaxis
GET80_21390	COG0604	alcohol dehydrogenase
GET80_21395	COG1609	Transcriptional regulator
GET80_21415	COG1519	Transferase
GET80_21420	COG0859	PFAM glycosyl transferase family 9
GET80_21425	COG0463	Glycosyl transferase, family 2
GET80_21430	COG0859	PFAM glycosyl transferase family 9
GET80_21435	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
GET80_21440	COG2990	Protein conserved in bacteria
GET80_21445	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
GET80_21455	COG0267	Belongs to the bacterial ribosomal protein bL33 family
GET80_21460	COG0227	Belongs to the bacterial ribosomal protein bL28 family
GET80_21465	COG2003	Belongs to the UPF0758 family
GET80_21470	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
GET80_21475	COG0756	dUTP diphosphatase activity
GET80_21480	COG1309	transcriptional regulator
GET80_21485	COG0668	transmembrane transport
GET80_21500	COG0166	Belongs to the GPI family
GET80_21505	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
GET80_21510	COG0583	DNA-binding transcription factor activity
GET80_21555	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
GET80_21560	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
GET80_21565	COG1739	Uncharacterized protein family UPF0029
GET80_21570	COG0006	proline dipeptidase activity
GET80_21575	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
GET80_21580	COG1024	Enoyl-CoA hydratase
GET80_21580	COG1250	3-hydroxyacyl-CoA dehydrogenase
GET80_21585	COG0183	Belongs to the thiolase family
GET80_21610	COG0425	Belongs to the sulfur carrier protein TusA family
GET80_21615	COG0251	oxidation-reduction process
GET80_21625	COG2885	chlorophyll binding
GET80_21635	COG2818	Glycosylase
GET80_21640	COG0752	glycyl-tRNA synthetase alpha subunit
GET80_21645	COG0751	glycine-tRNA ligase activity
GET80_21665	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
GET80_21680	COG0814	amino acid
GET80_21685	COG0348	domain, Protein
GET80_21695	COG0446	pyridine nucleotide-disulphide oxidoreductase
GET80_21700	COG0426	domain, Protein
GET80_21700	COG1773	rubredoxin
GET80_21705	COG3604	Transcriptional regulator
GET80_21710	COG2188	Transcriptional regulator
GET80_21725	COG1609	Transcriptional regulator
GET80_21765	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
GET80_21790	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
GET80_21805	COG3118	belongs to the thioredoxin family
GET80_21810	COG0513	Belongs to the DEAD box helicase family
GET80_21815	COG0248	Ppx GppA phosphatase
GET80_21830	COG0742	ribosomal rna small subunit methyltransferase
GET80_21850	COG0084	hydrolase, TatD family'
GET80_21855	COG0805	protein transport
GET80_21860	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
GET80_21870	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
GET80_21875	COG3165	ubiquinone biosynthetic process from chorismate
GET80_21885	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
GET80_21890	COG0402	S-adenosylhomocysteine deaminase activity
GET80_21905	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
GET80_21910	COG0848	biopolymer transport protein
GET80_21915	COG0811	peptide transport
GET80_21920	COG0811	peptide transport
GET80_21930	COG2771	luxR family
GET80_21935	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
GET80_21940	COG1349	DNA-binding transcription factor activity
GET80_21945	COG0745	RESPONSE REGULATOR receiver
GET80_21950	COG2205	protein histidine kinase activity
GET80_21960	COG4452	Inner membrane protein CreD
GET80_21965	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
GET80_21970	COG0355	proton-transporting ATP synthase activity, rotational mechanism
GET80_21975	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
GET80_21980	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
GET80_21985	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
GET80_21990	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
GET80_21995	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
GET80_22005	COG0356	it plays a direct role in the translocation of protons across the membrane
GET80_22015	COG1475	DNA binding
GET80_22020	COG1192	Involved in chromosome partitioning
GET80_22025	COG0357	Ribosomal RNA small subunit methyltransferase G
GET80_22030	COG0445	tRNA wobble uridine modification
GET80_22035	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
GET80_22040	COG4774	siderophore transport
GET80_22045	COG4615	Cyclic peptide transporter
GET80_22050	COG1120	ATPase activity
GET80_22065	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
GET80_22070	COG0706	membrane insertase activity
GET80_22075	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
GET80_22080	COG0594	ribonuclease P activity
GET80_22085	COG0230	Belongs to the bacterial ribosomal protein bL34 family
GET80_22090	COG1126	abc transporter atp-binding protein