locus-tag	class	description
MUW98_00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
MUW98_00010	COG0592	DNA-directed DNA polymerase activity
MUW98_00015	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
MUW98_00030	COG2378	regulation of single-species biofilm formation
MUW98_00035	COG0071	Belongs to the small heat shock protein (HSP20) family
MUW98_00040	COG0071	Belongs to the small heat shock protein (HSP20) family
MUW98_00045	COG3977	Valine--pyruvate aminotransferase
MUW98_00060	COG2814	Major facilitator Superfamily
MUW98_00065	COG0745	RESPONSE REGULATOR receiver
MUW98_00070	COG2205	protein histidine kinase activity
MUW98_00090	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
MUW98_00095	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
MUW98_00095	COG4191	Histidine kinase
MUW98_00100	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
MUW98_00105	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
MUW98_00150	COG0469	pyruvate kinase activity
MUW98_00155	COG2271	Major facilitator Superfamily
MUW98_00180	COG0561	phosphatase activity
MUW98_00185	COG2267	carboxylic ester hydrolase activity
MUW98_00190	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
MUW98_00195	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
MUW98_00200	COG1758	RNA polymerase activity
MUW98_00210	COG0859	PFAM glycosyl transferase family 9
MUW98_00215	COG3642	lipopolysaccharide core region biosynthetic process
MUW98_00255	COG0589	response to stress
MUW98_00260	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
MUW98_00270	COG1528	Iron-storage protein
MUW98_00275	COG2081	HI0933 family
MUW98_00280	COG2223	nitrite transmembrane transporter activity
MUW98_00300	COG3188	usher protein
MUW98_00320	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
MUW98_00320	COG2205	protein histidine kinase activity
MUW98_00330	COG3275	phosphorelay sensor kinase activity
MUW98_00335	COG3279	Response regulator of the LytR AlgR family
MUW98_00340	COG2223	nitrite transmembrane transporter activity
MUW98_00345	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
MUW98_00350	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
MUW98_00365	COG0583	DNA-binding transcription factor activity
MUW98_00370	COG4206	TonB-dependent receptor
MUW98_00375	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
MUW98_00410	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
MUW98_00415	COG2166	iron-sulfur cluster assembly
MUW98_00420	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
MUW98_00425	COG0210	DNA helicase
MUW98_00435	COG3245	cytochrome
MUW98_00440	COG1063	alcohol dehydrogenase
MUW98_00445	COG0156	8-amino-7-oxononanoate synthase activity
MUW98_00455	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
MUW98_00470	COG3306	glycosyltransferase involved in LPS biosynthesis
MUW98_00490	COG1561	YicC-like family, N-terminal region
MUW98_00495	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
MUW98_00500	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
MUW98_00510	COG0789	Transcriptional regulator
MUW98_00515	COG5001	Diguanylate cyclase
MUW98_00515	COG4251	negative regulation of phosphorylation
MUW98_00515	COG3706	GGDEF domain
MUW98_00515	COG2203	Gaf domain
MUW98_00520	COG3084	Protein conserved in bacteria
MUW98_00530	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
MUW98_00535	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
MUW98_00545	COG1335	isochorismatase
MUW98_00555	COG1683	Conserved Protein
MUW98_00560	COG0204	Acyl-transferase
MUW98_00565	COG0204	Acyl-transferase
MUW98_00570	COG0606	chelatase, subunit chli
MUW98_00580	COG3978	acetolactate synthase activity
MUW98_00590	COG0129	dihydroxy-acid dehydratase activity
MUW98_00620	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
MUW98_00625	COG0254	rRNA binding
MUW98_00630	COG0702	epimerase
MUW98_00635	COG0281	malic enzyme
MUW98_00645	COG2205	protein histidine kinase activity
MUW98_00650	COG0745	RESPONSE REGULATOR receiver
MUW98_00655	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
MUW98_00670	COG0366	Alpha amylase catalytic
MUW98_00685	COG0443	Heat shock 70 kDa protein
MUW98_00690	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MUW98_00695	COG3045	CreA protein
MUW98_00715	COG0174	glutamine synthetase
MUW98_00735	COG3842	ATPase activity
MUW98_00740	COG1176	ABC-type spermidine putrescine transport system, permease component I
MUW98_00745	COG1177	transmembrane transport
MUW98_00750	COG2258	MOSC domain
MUW98_00765	COG2050	protein possibly involved in aromatic compounds catabolism
MUW98_00770	COG0514	ATP-dependent DNA helicase (RecQ)
MUW98_00780	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
MUW98_00790	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
MUW98_00795	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
MUW98_00805	COG2239	Acts as a magnesium transporter
MUW98_00810	COG1648	precorrin-2 dehydrogenase activity
MUW98_00810	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
MUW98_00815	COG2116	formate transmembrane transporter activity
MUW98_00830	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
MUW98_00835	COG0842	Transport permease protein
MUW98_00840	COG0842	Transport permease protein
MUW98_00845	COG1131	(ABC) transporter
MUW98_00850	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
MUW98_00870	COG0477	Major facilitator Superfamily
MUW98_00875	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
MUW98_00880	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
MUW98_00900	COG1595	DNA-templated transcription, initiation
MUW98_00905	COG3806	Anti-sigma factor
MUW98_00910	COG1968	undecaprenyl-diphosphatase activity
MUW98_00915	COG0667	Aldo Keto reductase
MUW98_00920	COG2017	converts alpha-aldose to the beta-anomer
MUW98_00925	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
MUW98_00935	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
MUW98_00940	COG1609	Transcriptional regulator
MUW98_00945	COG3250	beta-galactosidase activity
MUW98_00965	COG0840	transmembrane signaling receptor activity
MUW98_00970	COG3328	transposase activity
MUW98_01000	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
MUW98_01005	COG1288	antiporter activity
MUW98_01010	COG1438	arginine binding
MUW98_01015	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
MUW98_01020	COG0540	Belongs to the ATCase OTCase family
MUW98_01040	COG0688	phosphatidylethanolamine metabolic process
MUW98_01050	COG3040	lipid binding
MUW98_01055	COG2207	Transcriptional regulator
MUW98_01060	COG1979	alcohol dehydrogenase
MUW98_01065	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
MUW98_01070	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
MUW98_01080	COG3681	Belongs to the UPF0597 family
MUW98_01090	COG0446	pyridine nucleotide-disulphide oxidoreductase
MUW98_01095	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
MUW98_01100	COG0564	pseudouridine synthase activity
MUW98_01110	COG0542	response to heat
MUW98_01115	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
MUW98_01120	COG2502	aspartate--ammonia ligase
MUW98_01125	COG1522	sequence-specific DNA binding
MUW98_01135	COG5413	integral membrane protein
MUW98_01160	COG2205	protein histidine kinase activity
MUW98_01170	COG2204	response regulator
MUW98_01185	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
MUW98_01215	COG0243	molybdopterin cofactor binding
MUW98_01220	COG3005	denitrification pathway
MUW98_01225	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
MUW98_01245	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
MUW98_01250	COG0569	domain protein
MUW98_01255	COG0812	UDP-N-acetylmuramate dehydrogenase activity
MUW98_01280	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
MUW98_01295	COG0250	Participates in transcription elongation, termination and antitermination
MUW98_01300	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
MUW98_01305	COG0081	regulation of translation
MUW98_01310	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
MUW98_01315	COG0222	ribosome binding
MUW98_01320	COG0085	RNA polymerase activity
MUW98_01325	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
MUW98_01330	COG2964	Protein conserved in bacteria
MUW98_01335	COG0251	oxidation-reduction process
MUW98_01345	COG2923	Belongs to the DsrF TusC family
MUW98_01350	COG2168	tRNA wobble position uridine thiolation
MUW98_01355	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
MUW98_01360	COG0049	tRNA binding
MUW98_01365	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
MUW98_01370	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
MUW98_01375	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
MUW98_01410	COG2252	PERMEase
MUW98_01415	COG2376	Dihydroxyacetone kinase
MUW98_01420	COG1461	Dihydroxyacetone kinase
MUW98_01435	COG3284	Transcriptional regulator
MUW98_01440	COG0583	DNA-binding transcription factor activity
MUW98_01445	COG2957	Belongs to the agmatine deiminase family
MUW98_01460	COG0628	permease
MUW98_01465	COG0494	nUDIX hydrolase
MUW98_01490	COG0753	catalase activity
MUW98_01495	COG1247	-acetyltransferase
MUW98_01515	COG2199	diguanylate cyclase activity
MUW98_01515	COG2203	Gaf domain
MUW98_01525	COG3842	ATPase activity
MUW98_01535	COG1175	transmembrane transport
MUW98_01560	COG0583	DNA-binding transcription factor activity
MUW98_01570	COG1741	Belongs to the pirin family
MUW98_01575	COG2259	Doxx family
MUW98_01580	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
MUW98_01585	COG1074	ATP-dependent DNA helicase activity
MUW98_01590	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
MUW98_01600	COG0346	lactoylglutathione lyase activity
MUW98_01645	COG4251	negative regulation of phosphorylation
MUW98_01645	COG5001	Diguanylate cyclase
MUW98_01645	COG2203	Gaf domain
MUW98_01645	COG3706	GGDEF domain
MUW98_01650	COG4771	TonB-dependent receptor
MUW98_01655	COG1278	Cold shock
MUW98_01690	COG2916	Histone family protein nucleoid-structuring protein H-NS
MUW98_01695	COG5499	transcription regulator containing HTH domain
MUW98_01710	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
MUW98_01725	COG1136	(ABC) transporter
MUW98_01740	COG1309	transcriptional regulator
MUW98_01745	COG5642	Protein of unknown function (DUF2384)
MUW98_01775	COG0629	single-stranded DNA binding
MUW98_01780	COG2197	response regulator
MUW98_01785	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
MUW98_01795	COG3047	cAMP biosynthetic process
MUW98_01800	COG0840	transmembrane signaling receptor activity
MUW98_01825	COG3135	benzoate transporter
MUW98_01830	COG1396	sequence-specific DNA binding
MUW98_01860	COG2926	Belongs to the UPF0265 family
MUW98_01870	COG3028	Belongs to the UPF0307 family
MUW98_01875	COG0312	modulator of DNA gyrase
MUW98_01880	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
MUW98_01885	COG5007	Belongs to the BolA IbaG family
MUW98_01895	COG2854	intermembrane phospholipid transfer
MUW98_01900	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
MUW98_01905	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
MUW98_01910	COG1127	ABC transporter
MUW98_01915	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
MUW98_01915	COG0517	IMP dehydrogenase activity
MUW98_01920	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
MUW98_01925	COG3117	lipopolysaccharide transmembrane transporter activity
MUW98_01930	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
MUW98_01935	COG1137	ATPase activity
MUW98_01940	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
MUW98_01950	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
MUW98_01955	COG1660	Displays ATPase and GTPase activities
MUW98_01960	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
MUW98_01965	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
MUW98_01965	COG3711	transcriptional antiterminator
MUW98_01980	COG3964	amidohydrolase
MUW98_02010	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
MUW98_02015	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
MUW98_02025	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
MUW98_02030	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
MUW98_02035	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
MUW98_02040	COG0723	plastoquinol--plastocyanin reductase activity
MUW98_02045	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
MUW98_02050	COG2857	Cytochrome c1
MUW98_02055	COG0625	glutathione transferase activity
MUW98_02060	COG2969	positive regulation of protein catabolic process
MUW98_02065	COG2823	Periplasmic or secreted lipoprotein
MUW98_02070	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
MUW98_02075	COG0792	nuclease activity
MUW98_02080	COG3107	peptidoglycan biosynthetic process
MUW98_02085	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
MUW98_02095	COG2001	Belongs to the MraZ family
MUW98_02100	COG0275	rRNA processing
MUW98_02105	COG3116	cell division
MUW98_02110	COG0768	penicillin binding
MUW98_02120	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
MUW98_02125	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
MUW98_02130	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
MUW98_02135	COG0772	Belongs to the SEDS family
MUW98_02140	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
MUW98_02145	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
MUW98_02150	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
MUW98_02155	COG0849	cell division
MUW98_02160	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
MUW98_02165	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
MUW98_02175	COG0653	protein targeting
MUW98_02185	COG0494	nUDIX hydrolase
MUW98_02190	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
MUW98_02195	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
MUW98_02210	COG1459	type II secretion system
MUW98_02215	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
MUW98_02240	COG2186	Transcriptional regulator
MUW98_02245	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
MUW98_02250	COG0508	dehydrogenase complex catalyzes the overall conversion of
MUW98_02255	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
MUW98_02265	COG0840	transmembrane signaling receptor activity
MUW98_02270	COG0840	transmembrane signaling receptor activity
MUW98_02275	COG1752	Esterase of the alpha-beta hydrolase superfamily
MUW98_02280	COG1049	propionate catabolic process, 2-methylcitrate cycle
MUW98_02285	COG2200	EAL domain
MUW98_02295	COG1280	lysine exporter protein (LysE YggA)
MUW98_02305	COG0523	cobalamin synthesis protein
MUW98_02310	COG0477	Major facilitator Superfamily
MUW98_02325	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
MUW98_02330	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
MUW98_02375	COG0784	Response regulator, receiver
MUW98_02375	COG0835	chemotaxis
MUW98_02380	COG1028	Short-chain dehydrogenase reductase Sdr
MUW98_02385	COG1444	tRNA N-acetyltransferase activity
MUW98_02410	COG1803	Methylglyoxal synthase
MUW98_02425	COG0252	asparaginase activity
MUW98_02445	COG1263	PTS System
MUW98_02445	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
MUW98_02450	COG0366	Alpha amylase catalytic
MUW98_02455	COG0110	maltose O-acetyltransferase activity
MUW98_02460	COG1522	sequence-specific DNA binding
MUW98_02465	COG5006	permease, DMT superfamily
MUW98_02475	COG1012	belongs to the aldehyde dehydrogenase family
MUW98_02480	COG1177	transmembrane transport
MUW98_02485	COG1176	ABC-type spermidine putrescine transport system, permease component I
MUW98_02490	COG3842	ATPase activity
MUW98_02495	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
MUW98_02500	COG0583	DNA-binding transcription factor activity
MUW98_02505	COG1757	Na H antiporter
MUW98_02545	COG0297	glycogen (starch) synthase activity
MUW98_02550	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
MUW98_02555	COG2813	Specifically methylates the guanine in position
MUW98_02560	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
MUW98_02565	COG3706	GGDEF domain
MUW98_02565	COG5001	Diguanylate cyclase
MUW98_02565	COG2203	Gaf domain
MUW98_02565	COG4251	negative regulation of phosphorylation
MUW98_02575	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
MUW98_02585	COG2995	paraquat-inducible protein a
MUW98_02590	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
MUW98_02590	COG3008	intermembrane lipid transfer
MUW98_02595	COG3009	Protein conserved in bacteria
MUW98_02600	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
MUW98_02600	COG2885	chlorophyll binding
MUW98_02610	COG3240	lipase activity
MUW98_02615	COG3111	PFAM Bacterial OB fold (BOF) protein
MUW98_02625	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
MUW98_02630	COG1194	a g-specific adenine glycosylase
MUW98_02640	COG3267	Type II secretory pathway component ExeA
MUW98_02640	COG3409	Peptidoglycan-binding domain 1 protein
MUW98_02645	COG0617	tRNA 3'-terminal CCA addition
MUW98_02660	COG1346	cytolysis
MUW98_02665	COG1380	Effector of murein hydrolase LrgA
MUW98_02670	COG0583	DNA-binding transcription factor activity
MUW98_02700	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
MUW98_02705	COG0306	phosphate transporter
MUW98_02710	COG1392	Phosphate transport regulator
MUW98_02725	COG1560	Kdo2-lipid A biosynthetic process
MUW98_02730	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
MUW98_02730	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
MUW98_02735	COG1538	Outer membrane efflux protein
MUW98_02740	COG0494	nUDIX hydrolase
MUW98_02745	COG3151	Protein conserved in bacteria
MUW98_02755	COG3150	esterase
MUW98_02760	COG1051	belongs to the nudix hydrolase family
MUW98_02775	COG1566	PFAM secretion protein HlyD family protein
MUW98_02780	COG1289	transmembrane transporter activity
MUW98_02785	COG0187	DNA topoisomerase II activity
MUW98_02805	COG0583	DNA-binding transcription factor activity
MUW98_02850	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
MUW98_02875	COG0204	Acyl-transferase
MUW98_02880	COG1842	Phage shock protein A
MUW98_02895	COG2827	Endonuclease containing a URI domain
MUW98_02905	COG2962	Rard protein
MUW98_02910	COG1573	uracil-dna glycosylase
MUW98_02915	COG0697	spore germination
MUW98_02920	COG0583	DNA-binding transcription factor activity
MUW98_02925	COG1108	ABC-type Mn2 Zn2 transport systems permease components
MUW98_02930	COG1121	(ABC) transporter
MUW98_02935	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
MUW98_02955	COG0739	heme binding
MUW98_02965	COG3068	Protein conserved in bacteria
MUW98_02985	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
MUW98_02990	COG1546	Belongs to the CinA family
MUW98_02995	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
MUW98_03005	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
MUW98_03010	COG0527	aspartate kinase activity
MUW98_03015	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
MUW98_03055	COG1686	Belongs to the peptidase S11 family
MUW98_03060	COG0586	Pfam SNARE associated Golgi protein
MUW98_03065	COG1253	flavin adenine dinucleotide binding
MUW98_03070	COG0525	valine-tRNA ligase activity
MUW98_03075	COG2927	DNA polymerase III (CHI subunit)
MUW98_03080	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
MUW98_03085	COG0795	lipopolysaccharide-transporting ATPase activity
MUW98_03090	COG0795	lipopolysaccharide-transporting ATPase activity
MUW98_03105	COG0582	viral genome integration into host DNA
MUW98_03165	COG4974	Belongs to the 'phage' integrase family
MUW98_03230	COG0732	type I restriction modification DNA specificity domain
MUW98_03230	COG0827	DNA restriction-modification system
MUW98_03255	COG4695	Portal protein
MUW98_03405	COG0004	ammonium transporteR
MUW98_03410	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
MUW98_03420	COG2165	general secretion pathway protein
MUW98_03425	COG0084	hydrolase, TatD family'
MUW98_03430	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
MUW98_03440	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
MUW98_03445	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
MUW98_03450	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
MUW98_03455	COG0813	purine-nucleoside phosphorylase activity
MUW98_03460	COG3447	MASE1 domain protein
MUW98_03460	COG5002	protein histidine kinase activity
MUW98_03460	COG5001	Diguanylate cyclase
MUW98_03470	COG0560	Phosphoserine phosphatase
MUW98_03495	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
MUW98_03505	COG0776	regulation of translation
MUW98_03520	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
MUW98_03525	COG0735	belongs to the Fur family
MUW98_03550	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
MUW98_03555	COG0513	Belongs to the DEAD box helicase family
MUW98_03560	COG3022	response to hydroperoxide
MUW98_03575	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
MUW98_03580	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
MUW98_03585	COG0762	integral membrane protein
MUW98_03590	COG1872	DUF167
MUW98_03605	COG4166	transmembrane transport
MUW98_03625	COG1024	Enoyl-CoA hydratase
MUW98_03640	COG4221	oxidoreductase activity
MUW98_03645	COG0442	prolyl-tRNA aminoacylation
MUW98_03650	COG0840	transmembrane signaling receptor activity
MUW98_03655	COG0632	four-way junction helicase activity
MUW98_03660	COG2255	four-way junction helicase activity
MUW98_03665	COG1271	oxidase subunit
MUW98_03670	COG1294	oxidase, subunit
MUW98_03675	COG4890	Cyd operon protein YbgT
MUW98_03680	COG3790	cyd operon protein YbgE
MUW98_03685	COG0824	Thioesterase
MUW98_03690	COG0811	peptide transport
MUW98_03705	COG0823	Involved in the tonB-independent uptake of proteins
MUW98_03710	COG2885	chlorophyll binding
MUW98_03715	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
MUW98_03760	COG0840	transmembrane signaling receptor activity
MUW98_03765	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
MUW98_03770	COG0676	glucose-6-phosphate 1-epimerase activity
MUW98_03775	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
MUW98_03780	COG1640	4-alpha-glucanotransferase
MUW98_03785	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
MUW98_03805	COG1051	belongs to the nudix hydrolase family
MUW98_03810	COG2130	NADP-dependent
MUW98_03815	COG1764	response to oxidative stress
MUW98_03820	COG1846	Transcriptional regulator
MUW98_03830	COG4584	PFAM Integrase catalytic
MUW98_03835	COG1484	DNA-dependent DNA replication
MUW98_03865	COG0561	phosphatase activity
MUW98_03880	COG0733	neurotransmitter:sodium symporter activity
MUW98_03890	COG0733	neurotransmitter:sodium symporter activity
MUW98_03915	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
MUW98_03930	COG1794	racemase activity, acting on amino acids and derivatives
MUW98_03945	COG2731	YhcH YjgK YiaL family protein
MUW98_03955	COG0668	transmembrane transport
MUW98_03965	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
MUW98_03995	COG0583	DNA-binding transcription factor activity
MUW98_04000	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
MUW98_04010	COG0488	(ABC) transporter
MUW98_04015	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
MUW98_04015	COG0517	IMP dehydrogenase activity
MUW98_04020	COG1585	Membrane protein implicated in regulation of membrane protease activity
MUW98_04025	COG0330	HflC and HflK could
MUW98_04030	COG1648	precorrin-2 dehydrogenase activity
MUW98_04030	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
MUW98_04035	COG0175	sulfate reduction
MUW98_04040	COG2895	sulfate adenylyltransferase (ATP) activity
MUW98_04045	COG3273	potassium ion transport
MUW98_04045	COG0471	metal ion transport
MUW98_04050	COG0529	Catalyzes the synthesis of activated sulfate
MUW98_04085	COG0840	transmembrane signaling receptor activity
MUW98_04105	COG1136	(ABC) transporter
MUW98_04120	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
MUW98_04135	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
MUW98_04140	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
MUW98_04145	COG0163	prenyltransferase activity
MUW98_04160	COG1131	(ABC) transporter
MUW98_04165	COG0842	Transport permease protein
MUW98_04170	COG1775	2-hydroxyglutaryl-CoA dehydratase, D-component
MUW98_04175	COG1924	4 iron, 4 sulfur cluster binding
MUW98_04195	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
MUW98_04200	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
MUW98_04215	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
MUW98_04220	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
MUW98_04225	COG1489	DNA binding
MUW98_04235	COG1643	Atp-dependent helicase
MUW98_04240	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
MUW98_04245	COG0346	lactoylglutathione lyase activity
MUW98_04255	COG2076	Multidrug Resistance protein
MUW98_04265	COG0784	Response regulator, receiver
MUW98_04265	COG3437	response regulator, receiver
MUW98_04275	COG0671	phosphoesterase, PA-phosphatase related
MUW98_04290	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
MUW98_04295	COG0038	chloride channel
MUW98_04305	COG0316	Belongs to the HesB IscA family
MUW98_04340	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
MUW98_04355	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
MUW98_04385	COG0745	RESPONSE REGULATOR receiver
MUW98_04390	COG3104	oligopeptide transport
MUW98_04395	COG1210	Utp--glucose-1-phosphate uridylyltransferase
MUW98_04400	COG1555	photosystem II stabilization
MUW98_04410	COG2350	Protein conserved in bacteria
MUW98_04415	COG2917	probably involved in intracellular septation
MUW98_04420	COG0076	glutamate decarboxylase activity
MUW98_04425	COG1272	protein, Hemolysin III
MUW98_04430	COG0569	domain protein
MUW98_04430	COG2985	domain, Protein
MUW98_04440	COG0835	chemotaxis
MUW98_04440	COG0784	Response regulator, receiver
MUW98_04445	COG2755	lipolytic protein G-D-S-L family
MUW98_04450	COG4181	ATPase activity
MUW98_04455	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
MUW98_04460	COG1090	epimerase
MUW98_04465	COG2200	EAL domain
MUW98_04470	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
MUW98_04475	COG4935	Belongs to the peptidase S8 family
MUW98_04475	COG2234	aminopeptidase activity
MUW98_04480	COG0220	tRNA (guanine-N7-)-methyltransferase activity
MUW98_04485	COG3171	Protein conserved in bacteria
MUW98_04490	COG2066	Belongs to the glutaminase family
MUW98_04495	COG2897	thiosulfate sulfurtransferase activity
MUW98_04505	COG1132	(ABC) transporter
MUW98_04525	COG0582	viral genome integration into host DNA
MUW98_04545	COG2314	TM2 domain
MUW98_04565	COG4974	Belongs to the 'phage' integrase family
MUW98_04640	COG3076	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome
MUW98_04645	COG3300	MHYT domain
MUW98_04645	COG5001	Diguanylate cyclase
MUW98_04655	COG2207	Transcriptional regulator
MUW98_04660	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
MUW98_04665	COG3059	membrane
MUW98_04685	COG4628	conserved protein (DUF2132)
MUW98_04690	COG0688	phosphatidylethanolamine metabolic process
MUW98_04695	COG1162	GTPase activity
MUW98_04700	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
MUW98_04740	COG1278	Cold shock
MUW98_04750	COG0840	transmembrane signaling receptor activity
MUW98_04755	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
MUW98_04805	COG0848	biopolymer transport protein
MUW98_04810	COG0811	peptide transport
MUW98_04815	COG0811	peptide transport
MUW98_04830	COG4174	ABC transporter (Permease)
MUW98_04835	COG4239	(ABC) transporter, permease
MUW98_04845	COG0444	Belongs to the ABC transporter superfamily
MUW98_04850	COG4608	Belongs to the ABC transporter superfamily
MUW98_04855	COG2195	Cleaves the N-terminal amino acid of tripeptides
MUW98_04860	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
MUW98_04865	COG1073	alpha beta
MUW98_04880	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
MUW98_04905	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
MUW98_04910	COG2313	pseudouridylate synthase activity
MUW98_04920	COG1858	cytochrome C peroxidase
MUW98_04955	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
MUW98_04960	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
MUW98_05020	COG1028	Short-chain dehydrogenase reductase Sdr
MUW98_05025	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
MUW98_05035	COG0521	Mo-molybdopterin cofactor biosynthetic process
MUW98_05045	COG2966	Psort location CytoplasmicMembrane, score
MUW98_05050	COG3610	response to peptide
MUW98_05060	COG4175	Glycine betaine
MUW98_05065	COG4176	ABC-type proline glycine betaine transport system permease component
MUW98_05070	COG2113	Glycine betaine
MUW98_05075	COG0175	sulfate reduction
MUW98_05080	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
MUW98_05085	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
MUW98_05090	COG0384	phenazine biosynthesis protein PhzF
MUW98_05095	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
MUW98_05110	COG0786	glutamate:sodium symporter activity
MUW98_05115	COG0252	asparaginase activity
MUW98_05120	COG3139	Protein of unknown function (DUF1315)
MUW98_05140	COG0616	signal peptide processing
MUW98_05145	COG1902	pentaerythritol trinitrate reductase activity
MUW98_05145	COG0446	pyridine nucleotide-disulphide oxidoreductase
MUW98_05150	COG0778	Nitroreductase
MUW98_05175	COG2264	protein methyltransferase activity
MUW98_05180	COG0604	alcohol dehydrogenase
MUW98_05185	COG0583	DNA-binding transcription factor activity
MUW98_05190	COG1263	PTS System
MUW98_05190	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
MUW98_05190	COG2190	(PTS) system
MUW98_05195	COG4145	pantothenate transmembrane transporter activity
MUW98_05205	COG0439	Biotin carboxylase
MUW98_05210	COG0511	ligase activity, forming carbon-carbon bonds
MUW98_05215	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
MUW98_05220	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
MUW98_05230	COG5001	Diguanylate cyclase
MUW98_05230	COG3300	MHYT domain
MUW98_05250	COG3381	protein complex oligomerization
MUW98_05265	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
MUW98_05275	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
MUW98_05280	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
MUW98_05280	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
MUW98_05300	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
MUW98_05305	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
MUW98_05310	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
MUW98_05315	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
MUW98_05320	COG4172	Belongs to the ABC transporter superfamily
MUW98_05330	COG0601	transmembrane transport
MUW98_05340	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
MUW98_05345	COG0142	geranyltranstransferase activity
MUW98_05350	COG1722	exodeoxyribonuclease VII activity
MUW98_05355	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
MUW98_05360	COG1360	Flagellar Motor Protein
MUW98_05375	COG1534	Rna-binding protein
MUW98_05380	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
MUW98_05390	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
MUW98_05395	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
MUW98_05400	COG0149	triose-phosphate isomerase activity
MUW98_05405	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
MUW98_05420	COG0779	Required for maturation of 30S ribosomal subunits
MUW98_05425	COG0195	Participates in both transcription termination and antitermination
MUW98_05430	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
MUW98_05435	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
MUW98_05440	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
MUW98_05445	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
MUW98_05450	COG1185	polyribonucleotide nucleotidyltransferase activity
MUW98_05455	COG2211	Major facilitator Superfamily
MUW98_05465	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
MUW98_05475	COG0114	fumarate hydratase activity
MUW98_05485	COG1966	Carbon starvation protein
MUW98_05490	COG3279	Response regulator of the LytR AlgR family
MUW98_05495	COG3275	phosphorelay sensor kinase activity
MUW98_05560	COG0312	modulator of DNA gyrase
MUW98_05565	COG0312	modulator of DNA gyrase
MUW98_05575	COG4974	Belongs to the 'phage' integrase family
MUW98_05585	COG1970	mechanosensitive ion channel activity
MUW98_05590	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
MUW98_05600	COG0789	Transcriptional regulator
MUW98_05615	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
MUW98_05620	COG3545	Serine hydrolase
MUW98_05630	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
MUW98_05635	COG0321	lipoyl(octanoyl) transferase activity
MUW98_05640	COG2921	Belongs to the UPF0250 family
MUW98_05645	COG1686	Belongs to the peptidase S11 family
MUW98_05650	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
MUW98_05655	COG2951	lytic endotransglycosylase activity
MUW98_05660	COG0772	Belongs to the SEDS family
MUW98_05665	COG0772	Belongs to the SEDS family
MUW98_05670	COG0768	penicillin binding
MUW98_05675	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
MUW98_05680	COG0799	negative regulation of ribosome biogenesis
MUW98_05685	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
MUW98_05700	COG0495	leucyl-tRNA aminoacylation
MUW98_05705	COG2888	peptidyl-tyrosine sulfation
MUW98_05710	COG0815	Transfers the fatty acyl group on membrane lipoproteins
MUW98_05715	COG4535	Mg2 and Co2 transporter CorC
MUW98_05720	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
MUW98_05725	COG1702	phosphate starvation-inducible protein PhoH
MUW98_05730	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
MUW98_05735	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
MUW98_05740	COG1335	isochorismatase
MUW98_05750	COG3706	GGDEF domain
MUW98_05765	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
MUW98_05785	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MUW98_05795	COG3647	Membrane
MUW98_05800	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
MUW98_05810	COG0516	GMP reductase activity
MUW98_05820	COG0642	Histidine kinase
MUW98_05860	COG3214	Protein conserved in bacteria
MUW98_05885	COG3029	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
MUW98_05890	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
MUW98_05895	COG1053	succinate dehydrogenase
MUW98_05905	COG0584	glycerophosphoryl diester phosphodiesterase
MUW98_05910	COG1511	domain protein
MUW98_05910	COG3264	Mechanosensitive ion channel
MUW98_05920	COG0739	heme binding
MUW98_05935	COG0583	DNA-binding transcription factor activity
MUW98_05955	COG0583	DNA-binding transcription factor activity
MUW98_05960	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
MUW98_05990	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
MUW98_05995	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
MUW98_06005	COG0338	D12 class N6 adenine-specific DNA methyltransferase
MUW98_06010	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
MUW98_06020	COG0180	Tryptophanyl-tRNA synthetase
MUW98_06035	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
MUW98_06045	COG1012	belongs to the aldehyde dehydrogenase family
MUW98_06055	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
MUW98_06065	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
MUW98_06065	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
MUW98_06065	COG1013	pyruvate-flavodoxin oxidoreductase activity
MUW98_06065	COG0674	pyruvate-flavodoxin oxidoreductase activity
MUW98_06075	COG0488	(ABC) transporter
MUW98_06085	COG0366	Alpha amylase catalytic
MUW98_06115	COG0471	metal ion transport
MUW98_06115	COG0490	domain, Protein
MUW98_06255	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
MUW98_06265	COG2003	Belongs to the UPF0758 family
MUW98_06305	COG0583	DNA-binding transcription factor activity
MUW98_06320	COG0549	Belongs to the carbamate kinase family
MUW98_06325	COG1304	FMN binding
MUW98_06330	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
MUW98_06335	COG1335	isochorismatase
MUW98_06360	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
MUW98_06365	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
MUW98_06370	COG4821	SIS domain
MUW98_06375	COG2188	Transcriptional regulator
MUW98_06380	COG1486	melibiose metabolic process
MUW98_06385	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
MUW98_06390	COG1447	Phosphotransferase system cellobiose-specific component IIA
MUW98_06410	COG1484	DNA-dependent DNA replication
MUW98_06415	COG4584	PFAM Integrase catalytic
MUW98_06425	COG0012	GTP binding
MUW98_06430	COG0193	aminoacyl-tRNA hydrolase activity
MUW98_06435	COG0737	Belongs to the 5'-nucleotidase family
MUW98_06440	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
MUW98_06450	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
MUW98_06455	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
MUW98_06460	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
MUW98_06465	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
MUW98_06470	COG2890	protein-(glutamine-N5) methyltransferase activity
MUW98_06480	COG2912	Transglutaminase-like superfamily
MUW98_06485	COG2877	3-deoxy-8-phosphooctulonate synthase activity
MUW98_06490	COG1301	dicarboxylic acid transport
MUW98_06500	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
MUW98_06515	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
MUW98_06520	COG1115	amino acid carrier protein
MUW98_06535	COG0714	Associated with various cellular activities
MUW98_06565	COG3104	oligopeptide transport
MUW98_06570	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
MUW98_06575	COG1678	Uncharacterized ACR, COG1678
MUW98_06585	COG0189	ligase activity
MUW98_06590	COG1385	rRNA (uridine-N3-)-methyltransferase activity
MUW98_06600	COG3091	SprT-like family
MUW98_06610	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
MUW98_06630	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
MUW98_06635	COG0739	heme binding
MUW98_06640	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
MUW98_06645	COG3408	Glycogen debranching enzyme
MUW98_06645	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
MUW98_06655	COG1881	PFAM PEBP family protein
MUW98_06660	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
MUW98_06665	COG0583	DNA-binding transcription factor activity
MUW98_06675	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
MUW98_06685	COG0583	DNA-binding transcription factor activity
MUW98_06690	COG1028	Short-chain dehydrogenase reductase Sdr
MUW98_06695	COG0616	signal peptide processing
MUW98_06700	COG3724	N-succinylarginine dihydrolase activity
MUW98_06720	COG0840	transmembrane signaling receptor activity
MUW98_06730	COG2971	BadF BadG BcrA BcrD
MUW98_06740	COG4608	Belongs to the ABC transporter superfamily
MUW98_06745	COG0444	Belongs to the ABC transporter superfamily
MUW98_06750	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
MUW98_06755	COG0601	transmembrane transport
MUW98_06760	COG4166	transmembrane transport
MUW98_06765	COG2205	protein histidine kinase activity
MUW98_06765	COG0784	Response regulator, receiver
MUW98_06795	COG3220	belongs to the UPF0276 family
MUW98_06825	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
MUW98_06830	COG1289	transmembrane transporter activity
MUW98_06835	COG0303	'Molybdopterin
MUW98_06840	COG0746	molybdenum cofactor guanylyltransferase activity
MUW98_06850	COG4662	Binding-protein-dependent transport system inner membrane component
MUW98_06860	COG2204	response regulator
MUW98_06865	COG3852	Histidine kinase
MUW98_06870	COG1910	domain protein
MUW98_06875	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
MUW98_06910	COG3383	formate dehydrogenase (NAD+) activity
MUW98_06910	COG3383	formate dehydrogenase (NAD+) activity
MUW98_06915	COG0437	4 iron, 4 sulfur cluster binding
MUW98_06930	COG0281	malic enzyme
MUW98_06950	COG2706	6-phosphogluconolactonase activity
MUW98_07025	COG1196	nuclear chromosome segregation
MUW98_07025	COG3264	Mechanosensitive ion channel
MUW98_07030	COG0469	pyruvate kinase activity
MUW98_07045	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
MUW98_07045	COG4651	solute:proton antiporter activity
MUW98_07055	COG2974	May be involved in recombination
MUW98_07065	COG0420	3'-5' exonuclease activity
MUW98_07070	COG0419	ATPase involved in DNA repair
MUW98_07080	COG3038	cytochrome b561
MUW98_07095	COG2190	(PTS) system
MUW98_07105	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
MUW98_07110	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
MUW98_07115	COG0542	response to heat
MUW98_07130	COG1720	tRNA m6t6A37 methyltransferase activity
MUW98_07150	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
MUW98_07155	COG4988	ABC transporter
MUW98_07170	COG0745	RESPONSE REGULATOR receiver
MUW98_07180	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
MUW98_07195	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
MUW98_07200	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
MUW98_07210	COG0083	homoserine kinase activity
MUW98_07215	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
MUW98_07225	COG0488	(ABC) transporter
MUW98_07250	COG0813	purine-nucleoside phosphorylase activity
MUW98_07265	COG2205	protein histidine kinase activity
MUW98_07265	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
MUW98_07270	COG3384	dioxygenase
MUW98_07280	COG1283	sodium-dependent phosphate transmembrane transporter activity
MUW98_07290	COG0531	amino acid
MUW98_07295	COG0531	amino acid
MUW98_07310	COG1917	Cupin 2, conserved barrel domain protein
MUW98_07310	COG1396	sequence-specific DNA binding
MUW98_07315	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
MUW98_07335	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
MUW98_07340	COG2375	cellular response to nickel ion
MUW98_07350	COG0577	efflux transmembrane transporter activity
MUW98_07350	COG1136	(ABC) transporter
MUW98_07355	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
MUW98_07365	COG1227	inorganic diphosphatase activity
MUW98_07370	COG0497	DNA recombination
MUW98_07375	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
MUW98_07380	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
MUW98_07385	COG0443	Heat shock 70 kDa protein
MUW98_07390	COG0484	heat shock protein binding
MUW98_07420	COG1285	pathogenesis
MUW98_07435	COG0640	Transcriptional regulator
MUW98_07465	COG0095	Lipoate-protein ligase
MUW98_07485	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
MUW98_07490	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
MUW98_07510	COG0708	Exodeoxyribonuclease III
MUW98_07525	COG2211	Major facilitator Superfamily
MUW98_07570	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
MUW98_07575	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
MUW98_07580	COG1845	cytochrome c oxidase, subunit III
MUW98_07585	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
MUW98_07590	COG0109	protoheme IX farnesyltransferase activity
MUW98_07595	COG2814	Major facilitator Superfamily
MUW98_07605	COG0784	Response regulator, receiver
MUW98_07605	COG2198	Histidine kinase
MUW98_07605	COG2205	protein histidine kinase activity
MUW98_07610	COG1879	ABC-type sugar transport system periplasmic component
MUW98_07620	COG0745	RESPONSE REGULATOR receiver
MUW98_07625	COG3005	denitrification pathway
MUW98_07635	COG3381	protein complex oligomerization
MUW98_07675	COG2003	Belongs to the UPF0758 family
MUW98_07725	COG3311	Transcriptional regulator
MUW98_07745	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
MUW98_07815	COG0159	tryptophan synthase activity
MUW98_07820	COG0133	tryptophan synthase activity
MUW98_07825	COG0135	phosphoribosylanthranilate isomerase activity
MUW98_07825	COG0134	indole-3-glycerol-phosphate synthase activity
MUW98_07830	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
MUW98_07835	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
MUW98_07835	COG0512	Glutamine amidotransferase of anthranilate synthase
MUW98_07840	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
MUW98_07850	COG0009	L-threonylcarbamoyladenylate synthase
MUW98_07860	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
MUW98_07870	COG1946	Acyl-CoA thioesterase
MUW98_07885	COG1309	transcriptional regulator
MUW98_07890	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
MUW98_07895	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
MUW98_07905	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
MUW98_07935	COG0482	sulfurtransferase activity
MUW98_07940	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
MUW98_07950	COG1086	Polysaccharide biosynthesis protein
MUW98_07975	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
MUW98_07990	COG1091	dTDP-4-dehydrorhamnose reductase activity
MUW98_07995	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
MUW98_08005	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
MUW98_08015	COG3132	Protein of unknown function, DUF480
MUW98_08055	COG1278	Cold shock
MUW98_08085	COG0697	spore germination
MUW98_08090	COG1349	DNA-binding transcription factor activity
MUW98_08095	COG1882	Formate acetyltransferase
MUW98_08100	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
MUW98_08105	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
MUW98_08135	COG0622	Phosphoesterase
MUW98_08150	COG1261	Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly
MUW98_08155	COG0784	Response regulator, receiver
MUW98_08155	COG0835	chemotaxis
MUW98_08160	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
MUW98_08165	COG1815	bacterial-type flagellum-dependent cell motility
MUW98_08185	COG4787	bacterial-type flagellum-dependent cell motility
MUW98_08195	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
MUW98_08200	COG1706	bacterial-type flagellum-dependent cell motility
MUW98_08205	COG3951	Flagellar rod assembly protein muramidase FlgJ
MUW98_08205	COG1705	Flagellar rod assembly protein muramidase FlgJ
MUW98_08210	COG1256	bacterial-type flagellum assembly
MUW98_08220	COG2239	Acts as a magnesium transporter
MUW98_08230	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
MUW98_08235	COG2716	regulation of RNA biosynthetic process
MUW98_08260	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
MUW98_08265	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
MUW98_08270	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
MUW98_08275	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
MUW98_08295	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
MUW98_08310	COG0590	tRNA wobble adenosine to inosine editing
MUW98_08315	COG0573	inorganic phosphate transmembrane transporter activity
MUW98_08320	COG0581	inorganic phosphate transmembrane transporter activity
MUW98_08325	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
MUW98_08330	COG0704	Plays a role in the regulation of phosphate uptake
MUW98_08335	COG1253	flavin adenine dinucleotide binding
MUW98_08350	COG0531	amino acid
MUW98_08370	COG1126	abc transporter atp-binding protein
MUW98_08375	COG0765	amino acid transport
MUW98_08380	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
MUW98_08390	COG2271	Major facilitator Superfamily
MUW98_08405	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
MUW98_08430	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
MUW98_08435	COG0477	Major facilitator Superfamily
MUW98_08440	COG0123	including yeast histone deacetylase and acetoin utilization protein
MUW98_08450	COG1199	ATP-dependent helicase activity
MUW98_08460	COG3328	transposase activity
MUW98_08470	COG1448	Aminotransferase
MUW98_08475	COG0433	COG0433 Predicted ATPase
MUW98_08490	COG0658	competence protein
MUW98_08490	COG2333	competence protein COMEC
MUW98_08500	COG1663	tetraacyldisaccharide 4'-kinase activity
MUW98_08505	COG2835	tetraacyldisaccharide 4'-kinase activity
MUW98_08510	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
MUW98_08515	COG2197	response regulator
MUW98_08520	COG0322	excinuclease ABC activity
MUW98_08575	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
MUW98_08580	COG0437	4 iron, 4 sulfur cluster binding
MUW98_08585	COG3301	Polysulphide reductase, NrfD
MUW98_08590	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
MUW98_08600	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
MUW98_08625	COG2199	diguanylate cyclase activity
MUW98_08625	COG2203	Gaf domain
MUW98_08655	COG2119	membrane
MUW98_08660	COG0023	Translation Initiation Factor
MUW98_08685	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
MUW98_08700	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
MUW98_08700	COG2205	protein histidine kinase activity
MUW98_08710	COG4138	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system
MUW98_08720	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
MUW98_08725	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
MUW98_08730	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
MUW98_08735	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
MUW98_08740	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
MUW98_08750	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
MUW98_08755	COG0505	Belongs to the CarA family
MUW98_08760	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
MUW98_08765	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
MUW98_08800	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
MUW98_08805	COG0513	Belongs to the DEAD box helicase family
MUW98_08815	COG4104	PAAR repeat-containing protein
MUW98_08830	COG0789	Transcriptional regulator
MUW98_08845	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
MUW98_08850	COG0765	amino acid transport
MUW98_08855	COG1126	abc transporter atp-binding protein
MUW98_08860	COG0493	'glutamate synthase
MUW98_08865	COG0067	glutamate synthase
MUW98_08865	COG0070	glutamate synthase
MUW98_08865	COG0069	glutamate synthase activity
MUW98_08870	COG1242	4 iron, 4 sulfur cluster binding
MUW98_08935	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
MUW98_08940	COG0574	Belongs to the PEP-utilizing enzyme family
MUW98_08940	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
MUW98_08970	COG1464	Belongs to the NlpA lipoprotein family
MUW98_08975	COG0671	phosphoesterase, PA-phosphatase related
MUW98_08980	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
MUW98_08985	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
MUW98_08995	COG0101	tRNA pseudouridine synthase activity
MUW98_09000	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
MUW98_09005	COG0285	dihydrofolate synthase activity
MUW98_09010	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
MUW98_09015	COG2920	part of a sulfur-relay system
MUW98_09020	COG1289	transmembrane transporter activity
MUW98_09025	COG0670	Belongs to the BI1 family
MUW98_09045	COG2194	sulfuric ester hydrolase activity
MUW98_09050	COG0392	lysyltransferase activity
MUW98_09050	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
MUW98_09060	COG0840	transmembrane signaling receptor activity
MUW98_09065	COG2199	diguanylate cyclase activity
MUW98_09065	COG2203	Gaf domain
MUW98_09070	COG0564	pseudouridine synthase activity
MUW98_09085	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
MUW98_09095	COG0625	glutathione transferase activity
MUW98_09110	COG0367	asparagine synthase
MUW98_09120	COG4651	solute:proton antiporter activity
MUW98_09120	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
MUW98_09125	COG0647	UMP catabolic process
MUW98_09135	COG1902	pentaerythritol trinitrate reductase activity
MUW98_09140	COG1253	flavin adenine dinucleotide binding
MUW98_09150	COG0247	lactate metabolic process
MUW98_09150	COG0277	FAD linked oxidase domain protein
MUW98_09160	COG2050	protein possibly involved in aromatic compounds catabolism
MUW98_09170	COG2056	Na+-H+ antiporter family
MUW98_09175	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
MUW98_09190	COG0346	lactoylglutathione lyase activity
MUW98_09195	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
MUW98_09200	COG4660	Part of a membrane complex involved in electron transport
MUW98_09205	COG4659	FMN binding
MUW98_09210	COG4658	electron transport chain
MUW98_09220	COG2878	Part of a membrane complex involved in electron transport
MUW98_09225	COG4657	Part of a membrane complex involved in electron transport
MUW98_09230	COG0697	spore germination
MUW98_09250	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
MUW98_09255	COG1288	antiporter activity
MUW98_09260	COG0436	Aminotransferase
MUW98_09270	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
MUW98_09275	COG2027	D-alanyl-D-alanine carboxypeptidase
MUW98_09280	COG1061	Type III restriction enzyme res subunit
MUW98_09285	COG1566	PFAM secretion protein HlyD family protein
MUW98_09295	COG1966	Carbon starvation protein
MUW98_09300	COG3279	Response regulator of the LytR AlgR family
MUW98_09305	COG3275	phosphorelay sensor kinase activity
MUW98_09310	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
MUW98_09310	COG2199	diguanylate cyclase activity
MUW98_09315	COG1012	belongs to the aldehyde dehydrogenase family
MUW98_09315	COG1454	alcohol dehydrogenase
MUW98_09325	COG2095	MarC family integral membrane protein
MUW98_09335	COG0601	transmembrane transport
MUW98_09340	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
MUW98_09355	COG0861	Integral membrane protein TerC family
MUW98_09360	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
MUW98_09370	COG1301	dicarboxylic acid transport
MUW98_09385	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
MUW98_09400	COG0537	adenosine 5'-monophosphoramidase activity
MUW98_09435	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
MUW98_09440	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
MUW98_09475	COG2354	Protein conserved in bacteria
MUW98_09490	COG2233	PERMEase
MUW98_09495	COG3150	esterase
MUW98_09500	COG1252	NADH dehydrogenase
MUW98_09520	COG0393	Putative heavy-metal-binding
MUW98_09535	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
MUW98_09535	COG1648	precorrin-2 dehydrogenase activity
MUW98_09555	COG4667	esterase of the alpha-beta hydrolase superfamily
MUW98_09560	COG1619	proteins homologs of microcin C7 resistance protein MccF
MUW98_09565	COG1368	sulfuric ester hydrolase activity
MUW98_09575	COG0527	aspartate kinase activity
MUW98_09580	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
MUW98_09580	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
MUW98_09585	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
MUW98_09605	COG0596	Alpha beta hydrolase
MUW98_09610	COG0346	lactoylglutathione lyase activity
MUW98_09620	COG0583	DNA-binding transcription factor activity
MUW98_09625	COG1620	l-lactate permease
MUW98_09630	COG0247	lactate metabolic process
MUW98_09635	COG1139	Iron-sulfur cluster binding protein
MUW98_09660	COG4584	PFAM Integrase catalytic
MUW98_09665	COG1484	DNA-dependent DNA replication
MUW98_09695	COG0577	efflux transmembrane transporter activity
MUW98_09700	COG1136	(ABC) transporter
MUW98_09710	COG2814	Major facilitator Superfamily
MUW98_09730	COG0672	)-iron permease
MUW98_09760	COG0659	secondary active sulfate transmembrane transporter activity
MUW98_09780	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
MUW98_09785	COG0840	transmembrane signaling receptor activity
MUW98_09795	COG2201	protein-glutamate methylesterase activity
MUW98_09805	COG0835	chemotaxis
MUW98_09810	COG3290	protein histidine kinase activity
MUW98_09810	COG0840	transmembrane signaling receptor activity
MUW98_09815	COG0643	Histidine kinase
MUW98_09815	COG2198	Histidine kinase
MUW98_09825	COG0745	RESPONSE REGULATOR receiver
MUW98_09830	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
MUW98_09835	COG0437	4 iron, 4 sulfur cluster binding
MUW98_09840	COG5557	Pfam Polysulphide reductase, NrfD
MUW98_09845	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
MUW98_09850	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
MUW98_09855	COG1773	rubredoxin
MUW98_09870	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
MUW98_09880	COG1124	(ABC) transporter
MUW98_09885	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
MUW98_09895	COG0375	protein maturation
MUW98_09900	COG0309	Hydrogenase expression formation protein (HypE)
MUW98_09910	COG0298	carbon dioxide binding
MUW98_09915	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
MUW98_09925	COG1921	L-seryl-tRNASec selenium transferase activity
MUW98_09935	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
MUW98_09945	COG3260	NADH ubiquinone oxidoreductase 20
MUW98_09950	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
MUW98_09955	COG3261	NADH dehydrogenase
MUW98_09955	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
MUW98_09960	COG0650	Formate hydrogenlyase subunit 4
MUW98_09965	COG0651	ATP synthesis coupled electron transport
MUW98_09970	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
MUW98_09975	COG3158	transport of potassium into the cell
MUW98_09990	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
MUW98_10005	COG3039	Transposase
MUW98_10020	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
MUW98_10025	COG0326	Molecular chaperone. Has ATPase activity
MUW98_10030	COG0563	adenylate kinase activity
MUW98_10035	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
MUW98_10040	COG3788	relative of glutathione S-transferase, MAPEG superfamily
MUW98_10045	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
MUW98_10060	COG3300	MHYT domain
MUW98_10060	COG5001	Diguanylate cyclase
MUW98_10065	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
MUW98_10085	COG1021	2,3-dihydroxybenzoate-AMP ligase
MUW98_10090	COG3433	isochorismatase activity
MUW98_10090	COG1535	isochorismatase
MUW98_10095	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
MUW98_10100	COG1028	Short-chain dehydrogenase reductase Sdr
MUW98_10110	COG3321	synthase
MUW98_10110	COG1028	Short-chain dehydrogenase reductase Sdr
MUW98_10110	COG0300	oxidoreductase activity
MUW98_10110	COG0318	PFAM AMP-dependent synthetase and ligase
MUW98_10110	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
MUW98_10115	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
MUW98_10125	COG1120	ATPase activity
MUW98_10130	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MUW98_10135	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MUW98_10140	COG4771	TonB-dependent receptor
MUW98_10180	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
MUW98_10185	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
MUW98_10190	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
MUW98_10205	COG1570	exodeoxyribonuclease VII activity
MUW98_10210	COG0697	spore germination
MUW98_10230	COG3158	transport of potassium into the cell
MUW98_10235	COG0516	GMP reductase activity
MUW98_10235	COG0517	IMP dehydrogenase activity
MUW98_10240	COG0518	GMP synthase (glutamine-hydrolyzing) activity
MUW98_10240	COG0519	Catalyzes the synthesis of GMP from XMP
MUW98_10285	COG2062	phosphohistidine phosphatase, SixA
MUW98_10295	COG0697	spore germination
MUW98_10300	COG4166	transmembrane transport
MUW98_10305	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
MUW98_10310	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
MUW98_10320	COG4591	ABC-type transport system involved in lipoprotein release permease component
MUW98_10325	COG1136	(ABC) transporter
MUW98_10330	COG4591	ABC-type transport system involved in lipoprotein release permease component
MUW98_10335	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
MUW98_10345	COG0544	peptidyl-prolyl cis-trans isomerase activity
MUW98_10350	COG0740	serine-type endopeptidase activity
MUW98_10355	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
MUW98_10360	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
MUW98_10365	COG0776	regulation of translation
MUW98_10370	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
MUW98_10375	COG0488	(ABC) transporter
MUW98_10380	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
MUW98_10385	COG3162	membrane
MUW98_10400	COG1024	Enoyl-CoA hydratase
MUW98_10420	COG1115	amino acid carrier protein
MUW98_10435	COG1584	GPR1 FUN34 yaaH family protein
MUW98_10470	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
MUW98_10475	COG1960	acyl-CoA dehydrogenase activity
MUW98_10485	COG1960	acyl-CoA dehydrogenase activity
MUW98_10490	COG1024	Enoyl-CoA hydratase
MUW98_10495	COG1024	Enoyl-CoA hydratase
MUW98_10505	COG1028	Short-chain dehydrogenase reductase Sdr
MUW98_10515	COG0730	response to heat
MUW98_10535	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
MUW98_10560	COG2003	Belongs to the UPF0758 family
MUW98_10610	COG5001	Diguanylate cyclase
MUW98_10610	COG3300	MHYT domain
MUW98_10615	COG0583	DNA-binding transcription factor activity
MUW98_10620	COG2723	6-phospho-beta-galactosidase activity
MUW98_10625	COG5001	Diguanylate cyclase
MUW98_10625	COG3300	MHYT domain
MUW98_10630	COG4584	PFAM Integrase catalytic
MUW98_10635	COG1484	DNA-dependent DNA replication
MUW98_10650	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
MUW98_10655	COG1028	Short-chain dehydrogenase reductase Sdr
MUW98_10660	COG0583	DNA-binding transcription factor activity
MUW98_10675	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
MUW98_10680	COG0673	inositol 2-dehydrogenase activity
MUW98_10685	COG0583	DNA-binding transcription factor activity
MUW98_10695	COG1560	Kdo2-lipid A biosynthetic process
MUW98_10700	COG1560	Kdo2-lipid A biosynthetic process
MUW98_10725	COG0417	DNA replication proofreading
MUW98_10755	COG0534	Mate efflux family protein
MUW98_10765	COG0307	riboflavin synthase, alpha
MUW98_10775	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
MUW98_10780	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
MUW98_10785	COG0697	spore germination
MUW98_10790	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
MUW98_10830	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
MUW98_10835	COG3099	Belongs to the UPF0263 family
MUW98_10840	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
MUW98_10845	COG2894	cell division
MUW98_10850	COG0850	regulation of cytokinetic process
MUW98_10855	COG3100	YcgL domain-containing protein
MUW98_10860	COG2951	lytic endotransglycosylase activity
MUW98_10865	COG1760	l-serine dehydratase
MUW98_10870	COG1760	l-serine dehydratase
MUW98_10875	COG3123	guanosine phosphorylase activity
MUW98_10895	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
MUW98_10900	COG2067	long-chain fatty acid transport protein
MUW98_10915	COG1595	DNA-templated transcription, initiation
MUW98_10945	COG0714	Associated with various cellular activities
MUW98_10950	COG0183	Belongs to the thiolase family
MUW98_10955	COG1024	Enoyl-CoA hydratase
MUW98_10955	COG1250	3-hydroxyacyl-CoA dehydrogenase
MUW98_10975	COG3829	transcription factor binding
MUW98_10980	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
MUW98_10985	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
MUW98_10990	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
MUW98_11000	COG0549	Belongs to the carbamate kinase family
MUW98_11005	COG0697	spore germination
MUW98_11015	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
MUW98_11015	COG3608	succinylglutamate desuccinylase aspartoacylase
MUW98_11020	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
MUW98_11030	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
MUW98_11030	COG0493	'glutamate synthase
MUW98_11035	COG0402	S-adenosylhomocysteine deaminase activity
MUW98_11040	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
MUW98_11045	COG1529	Aldehyde oxidase and xanthine dehydrogenase
MUW98_11045	COG2080	2 iron, 2 sulfur cluster binding
MUW98_11050	COG2233	PERMEase
MUW98_11055	COG0402	S-adenosylhomocysteine deaminase activity
MUW98_11060	COG2252	PERMEase
MUW98_11065	COG1529	Aldehyde oxidase and xanthine dehydrogenase
MUW98_11070	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
MUW98_11075	COG2080	2 iron, 2 sulfur cluster binding
MUW98_11085	COG3134	Outer membrane lipoprotein
MUW98_11095	COG1288	antiporter activity
MUW98_11100	COG0318	PFAM AMP-dependent synthetase and ligase
MUW98_11110	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
MUW98_11110	COG0140	phosphoribosyl-ATP diphosphatase activity
MUW98_11115	COG0107	imidazoleglycerol-phosphate synthase activity
MUW98_11120	COG0784	Response regulator, receiver
MUW98_11120	COG2198	Histidine kinase
MUW98_11120	COG2205	protein histidine kinase activity
MUW98_11125	COG2199	diguanylate cyclase activity
MUW98_11130	COG3437	response regulator, receiver
MUW98_11135	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
MUW98_11140	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
MUW98_11145	COG0131	Imidazoleglycerol-phosphate dehydratase
MUW98_11145	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
MUW98_11150	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
MUW98_11155	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
MUW98_11160	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
MUW98_11170	COG1199	ATP-dependent helicase activity
MUW98_11175	COG1214	PFAM Peptidase M22, glycoprotease
MUW98_11185	COG0596	Alpha beta hydrolase
MUW98_11185	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
MUW98_11185	COG2226	methyltransferase
MUW98_11190	COG0318	PFAM AMP-dependent synthetase and ligase
MUW98_11210	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
MUW98_11215	COG2832	Protein of unknown function (DUF454)
MUW98_11220	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
MUW98_11230	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
MUW98_11245	COG0517	IMP dehydrogenase activity
MUW98_11245	COG0617	tRNA 3'-terminal CCA addition
MUW98_11245	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
MUW98_11250	COG1643	Atp-dependent helicase
MUW98_11260	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
MUW98_11270	COG3437	response regulator, receiver
MUW98_11275	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
MUW98_11280	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
MUW98_11285	COG0709	Synthesizes selenophosphate from selenide and ATP
MUW98_11300	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
MUW98_11305	COG0840	transmembrane signaling receptor activity
MUW98_11310	COG1254	Belongs to the acylphosphatase family
MUW98_11320	COG0625	glutathione transferase activity
MUW98_11325	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
MUW98_11325	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
MUW98_11330	COG0489	protein tyrosine kinase activity
MUW98_11335	COG0572	uridine kinase
MUW98_11340	COG0717	Belongs to the dCTP deaminase family
MUW98_11345	COG0306	phosphate transporter
MUW98_11350	COG1530	ribonuclease E activity
MUW98_11355	COG0564	pseudouridine synthase activity
MUW98_11360	COG0546	phosphoglycolate phosphatase activity
MUW98_11365	COG0424	maF-like protein
MUW98_11370	COG2814	Major facilitator Superfamily
MUW98_11385	COG1399	metal-binding, possibly nucleic acid-binding protein
MUW98_11390	COG0333	Belongs to the bacterial ribosomal protein bL32 family
MUW98_11395	COG0416	fatty acid biosynthetic process
MUW98_11400	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
MUW98_11410	COG1028	Short-chain dehydrogenase reductase Sdr
MUW98_11415	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
MUW98_11425	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
MUW98_11430	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
MUW98_11435	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
MUW98_11440	COG0470	DNA polymerase III
MUW98_11445	COG0084	hydrolase, TatD family'
MUW98_11460	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
MUW98_11460	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
MUW98_11465	COG3008	intermembrane lipid transfer
MUW98_11470	COG2995	paraquat-inducible protein a
MUW98_11480	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
MUW98_11485	COG0372	Belongs to the citrate synthase family
MUW98_11530	COG4221	oxidoreductase activity
MUW98_11540	COG3141	response to X-ray
MUW98_11630	COG5499	transcription regulator containing HTH domain
MUW98_11640	COG1609	Transcriptional regulator
MUW98_11665	COG1064	alcohol dehydrogenase
MUW98_11670	COG0583	DNA-binding transcription factor activity
MUW98_11675	COG0667	Aldo Keto reductase
MUW98_11740	COG0840	transmembrane signaling receptor activity
MUW98_11760	COG3173	Aminoglycoside phosphotransferase
MUW98_11785	COG1695	Transcriptional regulator
MUW98_11800	COG3328	transposase activity
MUW98_11830	COG1132	(ABC) transporter
MUW98_11865	COG2161	toxin-antitoxin pair type II binding
MUW98_11870	COG4115	mRNA cleavage
MUW98_11905	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
MUW98_11925	COG1028	Short-chain dehydrogenase reductase Sdr
MUW98_11940	COG1028	Short-chain dehydrogenase reductase Sdr
MUW98_11945	COG0656	L-ascorbic acid biosynthetic process
MUW98_11970	COG5002	protein histidine kinase activity
MUW98_11980	COG0667	Aldo Keto reductase
MUW98_11990	COG2814	Major facilitator Superfamily
MUW98_12005	COG0667	Aldo Keto reductase
MUW98_12010	COG1979	alcohol dehydrogenase
MUW98_12015	COG0583	DNA-binding transcription factor activity
MUW98_12020	COG5642	Protein of unknown function (DUF2384)
MUW98_12050	COG1067	ATP-dependent peptidase activity
MUW98_12055	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
MUW98_12070	COG0488	(ABC) transporter
MUW98_12080	COG0116	Belongs to the methyltransferase superfamily
MUW98_12080	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
MUW98_12090	COG0167	dihydroorotate dehydrogenase activity
MUW98_12095	COG2902	Dehydrogenase
MUW98_12105	COG0308	aminopeptidase N
MUW98_12115	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
MUW98_12120	COG1956	GAF domain-containing protein
MUW98_12130	COG3278	Belongs to the heme-copper respiratory oxidase family
MUW98_12145	COG2010	Cytochrome c
MUW98_12170	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
MUW98_12175	COG0589	response to stress
MUW98_12180	COG0037	tRNA processing
MUW98_12195	COG0625	glutathione transferase activity
MUW98_12200	COG1869	D-ribose catabolic process
MUW98_12205	COG1129	ABC transporter
MUW98_12210	COG1172	Belongs to the binding-protein-dependent transport system permease family
MUW98_12215	COG1879	ABC-type sugar transport system periplasmic component
MUW98_12220	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
MUW98_12225	COG1609	Transcriptional regulator
MUW98_12230	COG3300	MHYT domain
MUW98_12230	COG5001	Diguanylate cyclase
MUW98_12260	COG0776	regulation of translation
MUW98_12265	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
MUW98_12265	COG0072	phenylalanine-tRNA ligase activity
MUW98_12270	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
MUW98_12275	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
MUW98_12280	COG0291	Belongs to the bacterial ribosomal protein bL35 family
MUW98_12285	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
MUW98_12290	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
MUW98_12315	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
MUW98_12325	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MUW98_12330	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MUW98_12335	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
MUW98_12340	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
MUW98_12345	COG3313	Fe-S protein
MUW98_12350	COG2942	2-epimerase
MUW98_12355	COG3716	PTS system mannose fructose sorbose family IID component
MUW98_12360	COG3715	PTS system
MUW98_12365	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
MUW98_12365	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
MUW98_12380	COG1609	Transcriptional regulator
MUW98_12385	COG2140	Oxalate decarboxylase
MUW98_12390	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
MUW98_12390	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
MUW98_12390	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
MUW98_12395	COG1105	Belongs to the carbohydrate kinase PfkB family
MUW98_12400	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
MUW98_12400	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
MUW98_12405	COG1609	Transcriptional regulator
MUW98_12410	COG0814	amino acid
MUW98_12420	COG5654	RES domain protein
MUW98_12425	COG0513	Belongs to the DEAD box helicase family
MUW98_12435	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
MUW98_12440	COG2890	protein-(glutamine-N5) methyltransferase activity
MUW98_12445	COG2840	Smr protein MutS2
MUW98_12455	COG3706	GGDEF domain
MUW98_12460	COG0406	alpha-ribazole phosphatase activity
MUW98_12490	COG2824	Alkylphosphonate utilization operon protein PhnA
MUW98_12500	COG0384	phenazine biosynthesis protein PhzF
MUW98_12530	COG0242	peptide deformylase activity
MUW98_12550	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
MUW98_12555	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
MUW98_12565	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
MUW98_12570	COG1434	Gram-negative-bacterium-type cell wall biogenesis
MUW98_12580	COG0205	6-phosphofructokinase activity
MUW98_12585	COG1473	amidohydrolase
MUW98_12590	COG1011	Hydrolase
MUW98_12595	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
MUW98_12645	COG3593	DNA synthesis involved in DNA repair
MUW98_12660	COG0583	DNA-binding transcription factor activity
MUW98_12665	COG0730	response to heat
MUW98_12670	COG3148	PFAM DTW domain containing protein
MUW98_12680	COG1181	Belongs to the D-alanine--D-alanine ligase family
MUW98_12690	COG0386	Belongs to the glutathione peroxidase family
MUW98_12695	COG0513	Belongs to the DEAD box helicase family
MUW98_12700	COG0456	acetyltransferase
MUW98_12710	COG1742	UPF0060 membrane protein
MUW98_12740	COG2329	Antibiotic biosynthesis monooxygenase
MUW98_12745	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
MUW98_12775	COG2501	S4 domain
MUW98_12790	COG1132	(ABC) transporter
MUW98_12795	COG1132	(ABC) transporter
MUW98_12805	COG3118	belongs to the thioredoxin family
MUW98_12810	COG0471	metal ion transport
MUW98_12815	COG0058	SHG alpha-glucan phosphorylase activity
MUW98_12845	COG0814	amino acid
MUW98_12850	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
MUW98_12855	COG0514	ATP-dependent DNA helicase (RecQ)
MUW98_12860	COG2766	serine protein kinase
MUW98_12870	COG2719	SpoVR family
MUW98_12875	COG2186	Transcriptional regulator
MUW98_12880	COG3067	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
MUW98_12885	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
MUW98_12890	COG0586	Pfam SNARE associated Golgi protein
MUW98_12900	COG0556	nucleotide-excision repair
MUW98_12910	COG0569	domain protein
MUW98_12910	COG2985	domain, Protein
MUW98_12935	COG4565	transcriptional regulatory protein
MUW98_12940	COG3290	protein histidine kinase activity
MUW98_12945	COG1846	Transcriptional regulator
MUW98_12945	COG1940	carbohydrate kinase activity
MUW98_12950	COG0840	transmembrane signaling receptor activity
MUW98_12955	COG3012	SEC-C Motif Domain Protein
MUW98_12960	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
MUW98_12965	COG3075	Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses fumarate or nitrate as electron acceptor
MUW98_12970	COG0247	lactate metabolic process
MUW98_12990	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
MUW98_12995	COG0437	4 iron, 4 sulfur cluster binding
MUW98_13000	COG3301	Polysulphide reductase, NrfD
MUW98_13005	COG1138	Cytochrome C-type biogenesis protein
MUW98_13010	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
MUW98_13015	COG3088	subunit of a heme lyase
MUW98_13015	COG4235	cytochrome complex assembly
MUW98_13020	COG1051	belongs to the nudix hydrolase family
MUW98_13030	COG3033	Beta-eliminating lyase
MUW98_13040	COG3046	protein related to deoxyribodipyrimidine photolyase
MUW98_13045	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
MUW98_13070	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
MUW98_13085	COG4774	siderophore transport
MUW98_13090	COG4977	sequence-specific DNA binding
MUW98_13100	COG0583	DNA-binding transcription factor activity
MUW98_13105	COG2910	NAD(P)H-binding
MUW98_13120	COG0612	Peptidase, M16
MUW98_13125	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
MUW98_13135	COG1944	ATP diphosphatase activity
MUW98_13140	COG2116	formate transmembrane transporter activity
MUW98_13145	COG1882	Formate acetyltransferase
MUW98_13150	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
MUW98_13155	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
MUW98_13160	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
MUW98_13170	COG1840	ABC-type Fe3 transport system, periplasmic component
MUW98_13175	COG3842	ATPase activity
MUW98_13185	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
MUW98_13190	COG2983	Belongs to the UPF0260 family
MUW98_13205	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
MUW98_13210	COG0045	succinate-CoA ligase (ADP-forming) activity
MUW98_13215	COG0508	dehydrogenase complex catalyzes the overall conversion of
MUW98_13220	COG0567	Dehydrogenase, E1 component
MUW98_13230	COG1053	succinate dehydrogenase
MUW98_13235	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
MUW98_13260	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
MUW98_13265	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
MUW98_13265	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
MUW98_13275	COG3069	C4-dicarboxylate transmembrane transporter activity
MUW98_13290	COG1451	nucleotide metabolic process
MUW98_13305	COG0254	rRNA binding
MUW98_13310	COG0257	Belongs to the bacterial ribosomal protein bL36 family
MUW98_13320	COG0583	DNA-binding transcription factor activity
MUW98_13340	COG1879	ABC-type sugar transport system periplasmic component
MUW98_13345	COG1069	ribulokinase activity
MUW98_13355	COG2160	L-arabinose isomerase activity
MUW98_13360	COG2925	Exonuclease
MUW98_13370	COG3345	alpha-galactosidase
MUW98_13375	COG1380	Effector of murein hydrolase LrgA
MUW98_13380	COG1346	cytolysis
MUW98_13385	COG0295	cytidine deaminase activity
MUW98_13390	COG1022	Amp-dependent synthetase and ligase
MUW98_13405	COG0861	Integral membrane protein TerC family
MUW98_13410	COG2885	chlorophyll binding
MUW98_13415	COG2199	diguanylate cyclase activity
MUW98_13440	COG2154	pterin-4-alpha-carbinolamine dehydratase
MUW98_13450	COG3768	UPF0283 membrane protein
MUW98_13455	COG3106	COG3106 Predicted ATPase
MUW98_13470	COG1842	Phage shock protein A
MUW98_13475	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
MUW98_13485	COG4168	peptide transport system, permease
MUW98_13490	COG4171	peptide transport system, permease
MUW98_13500	COG4172	Belongs to the ABC transporter superfamily
MUW98_13510	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
MUW98_13515	COG1286	toxin biosynthetic process
MUW98_13520	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
MUW98_13525	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
MUW98_13530	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
MUW98_13535	COG0531	amino acid
MUW98_13535	COG1674	ftsk spoiiie
MUW98_13545	COG0686	Belongs to the AlaDH PNT family
MUW98_13550	COG0492	ferredoxin-NADP+ reductase activity
MUW98_13555	COG3706	GGDEF domain
MUW98_13560	COG3134	Outer membrane lipoprotein
MUW98_13565	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
MUW98_13570	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
MUW98_13575	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
MUW98_13580	COG0542	response to heat
MUW98_13585	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
MUW98_13590	COG1278	Cold shock
MUW98_13595	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
MUW98_13630	COG4584	PFAM Integrase catalytic
MUW98_13635	COG1484	DNA-dependent DNA replication
MUW98_13650	COG4372	Transposase
MUW98_13670	COG3328	transposase activity
MUW98_13730	COG3550	peptidyl-serine autophosphorylation
MUW98_13735	COG4584	PFAM Integrase catalytic
MUW98_13740	COG1484	DNA-dependent DNA replication
MUW98_13805	COG3829	transcription factor binding
MUW98_13880	COG3501	Rhs element vgr protein
MUW98_13910	COG1435	thymidine kinase activity
MUW98_13915	COG1757	Na H antiporter
MUW98_13925	COG2916	Histone family protein nucleoid-structuring protein H-NS
MUW98_13930	COG2096	Adenosyltransferase
MUW98_13935	COG3530	Putative quorum-sensing-regulated virulence factor
MUW98_13940	COG0602	queuosine metabolic process
MUW98_13945	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
MUW98_13965	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
MUW98_13975	COG0776	regulation of translation
MUW98_13980	COG0539	negative regulation of cytoplasmic translation
MUW98_13985	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
MUW98_13990	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
MUW98_14000	COG0583	DNA-binding transcription factor activity
MUW98_14020	COG0778	Nitroreductase
MUW98_14025	COG5001	Diguanylate cyclase
MUW98_14025	COG3300	MHYT domain
MUW98_14035	COG0583	DNA-binding transcription factor activity
MUW98_14040	COG3437	response regulator, receiver
MUW98_14065	COG4989	oxidoreductase activity
MUW98_14070	COG0724	RNA recognition motif
MUW98_14090	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
MUW98_14105	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
MUW98_14110	COG1360	Flagellar Motor Protein
MUW98_14115	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
MUW98_14120	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
MUW98_14125	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
MUW98_14125	COG0649	NAD binding
MUW98_14140	COG1034	ATP synthesis coupled electron transport
MUW98_14145	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
MUW98_14150	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
MUW98_14155	COG0839	Belongs to the complex I subunit 6 family
MUW98_14160	COG0713	ATP synthesis coupled electron transport
MUW98_14170	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
MUW98_14175	COG1007	ATP synthesis coupled electron transport
MUW98_14180	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
MUW98_14180	COG0047	phosphoribosylformylglycinamidine synthase activity
MUW98_14185	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
MUW98_14190	COG1645	bacterial-type flagellum-dependent swarming motility
MUW98_14195	COG1160	GTP binding
MUW98_14200	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
MUW98_14205	COG2976	Protein conserved in bacteria
MUW98_14210	COG0124	histidyl-tRNA synthetase
MUW98_14215	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
MUW98_14230	COG0820	rRNA (adenine-C2-)-methyltransferase activity
MUW98_14235	COG0105	UTP biosynthetic process
MUW98_14240	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
MUW98_14250	COG0633	Ferredoxin
MUW98_14255	COG0443	Heat shock 70 kDa protein
MUW98_14260	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
MUW98_14270	COG0822	iron-sulfur transferase activity
MUW98_14275	COG1104	cysteine desulfurase activity
MUW98_14295	COG3154	lipid carrier protein
MUW98_14300	COG0826	peptidase U32
MUW98_14305	COG0826	peptidase U32
MUW98_14320	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
MUW98_14325	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
MUW98_14330	COG1862	Preprotein translocase
MUW98_14335	COG0343	queuine tRNA-ribosyltransferase activity
MUW98_14340	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
MUW98_14345	COG0517	IMP dehydrogenase activity
MUW98_14355	COG3634	alkyl hydroperoxide reductase activity
MUW98_14375	COG1393	Belongs to the ArsC family
MUW98_14380	COG0798	PFAM Bile acid sodium symporter
MUW98_14410	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
MUW98_14410	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
MUW98_14415	COG0509	glycine decarboxylation via glycine cleavage system
MUW98_14420	COG0404	The glycine cleavage system catalyzes the degradation of glycine
MUW98_14425	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
MUW98_14430	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
MUW98_14450	COG2814	Major facilitator Superfamily
MUW98_14455	COG0625	glutathione transferase activity
MUW98_14465	COG0483	inositol monophosphate 1-phosphatase activity
MUW98_14485	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
MUW98_14505	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
MUW98_14515	COG2089	acid synthase
MUW98_14520	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
MUW98_14540	COG1083	cytidylyl-transferase
MUW98_14570	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
MUW98_14590	COG0301	tRNA thio-modification
MUW98_14590	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
MUW98_14600	COG4953	penicillin-binding protein 1C
MUW98_14605	COG2373	Large extracellular alpha-helical protein
MUW98_14610	COG0446	pyridine nucleotide-disulphide oxidoreductase
MUW98_14620	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
MUW98_14640	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
MUW98_14650	COG2431	L-lysine efflux transmembrane transporter activity
MUW98_14655	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
MUW98_14660	COG3124	Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP
MUW98_14675	COG1393	Belongs to the ArsC family
MUW98_14685	COG4783	chaperone-mediated protein folding
MUW98_14690	COG0425	Belongs to the sulfur carrier protein TusA family
MUW98_14715	COG3842	ATPase activity
MUW98_14720	COG3833	ABC-type maltose transport systems, permease component
MUW98_14725	COG1175	transmembrane transport
MUW98_14735	COG3081	Nucleoid-associated protein
MUW98_14740	COG3082	Protein of unknown function (DUF1414)
MUW98_14745	COG3083	sulfuric ester hydrolase activity
MUW98_14750	COG4771	TonB-dependent receptor
MUW98_14755	COG1770	oligopeptidase
MUW98_14775	COG4574	serine-type endopeptidase inhibitor activity
MUW98_14780	COG3085	chromosome segregation
MUW98_14785	COG0583	DNA-binding transcription factor activity
MUW98_14790	COG0287	Prephenate dehydrogenase
MUW98_14790	COG1605	Chorismate mutase
MUW98_14795	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
MUW98_14800	COG0584	glycerophosphoryl diester phosphodiesterase
MUW98_14815	COG1349	DNA-binding transcription factor activity
MUW98_14835	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
MUW98_14840	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
MUW98_14845	COG0583	DNA-binding transcription factor activity
MUW98_14870	COG0656	L-ascorbic acid biosynthetic process
MUW98_14875	COG2814	Major facilitator Superfamily
MUW98_14885	COG1294	oxidase, subunit
MUW98_14890	COG1271	oxidase subunit
MUW98_14895	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
MUW98_14905	COG2979	Protein of unknown function (DUF533)
MUW98_14930	COG2271	Major facilitator Superfamily
MUW98_14935	COG0583	DNA-binding transcription factor activity
MUW98_14945	COG2807	transmembrane transport
MUW98_14950	COG1187	pseudouridine synthase activity
MUW98_14975	COG1403	HNH endonuclease
MUW98_14990	COG3681	Belongs to the UPF0597 family
MUW98_15000	COG0814	amino acid
MUW98_15020	COG1166	arginine decarboxylase activity
MUW98_15030	COG2195	Cleaves the N-terminal amino acid of tripeptides
MUW98_15060	COG0583	DNA-binding transcription factor activity
MUW98_15070	COG2759	Belongs to the formate--tetrahydrofolate ligase family
MUW98_15075	COG0840	transmembrane signaling receptor activity
MUW98_15080	COG0302	gtp cyclohydrolase
MUW98_15090	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
MUW98_15095	COG2267	carboxylic ester hydrolase activity
MUW98_15100	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
MUW98_15115	COG0314	molybdopterin synthase activity
MUW98_15120	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
MUW98_15125	COG0315	cyclic pyranopterin monophosphate synthase activity
MUW98_15130	COG0521	Mo-molybdopterin cofactor biosynthetic process
MUW98_15135	COG3005	denitrification pathway
MUW98_15145	COG0348	domain, Protein
MUW98_15150	COG0437	4 iron, 4 sulfur cluster binding
MUW98_15155	COG0243	molybdopterin cofactor binding
MUW98_15165	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
MUW98_15165	COG1149	4fe-4S ferredoxin, iron-sulfur binding domain protein
MUW98_15170	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
MUW98_15175	COG3850	Histidine kinase
MUW98_15180	COG2197	response regulator
MUW98_15210	COG0121	glutamine amidotransferase
MUW98_15215	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
MUW98_15220	COG1960	acyl-CoA dehydrogenase activity
MUW98_15225	COG0784	Response regulator, receiver
MUW98_15225	COG3437	response regulator, receiver
MUW98_15240	COG0328	RNA-DNA hybrid ribonuclease activity
MUW98_15245	COG2226	methyltransferase
MUW98_15250	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
MUW98_15255	COG0741	lytic transglycosylase activity
MUW98_15255	COG1388	LysM domain
MUW98_15260	COG3021	interspecies interaction between organisms
MUW98_15270	COG1607	acyl-coa hydrolase
MUW98_15285	COG0741	lytic transglycosylase activity
MUW98_15295	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
MUW98_15315	COG2911	Protein conserved in bacteria
MUW98_15320	COG0729	surface antigen
MUW98_15330	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
MUW98_15335	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
MUW98_15345	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
MUW98_15355	COG4134	Bacterial extracellular solute-binding protein
MUW98_15365	COG4136	ATPase activity
MUW98_15370	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
MUW98_15375	COG2951	lytic endotransglycosylase activity
MUW98_15390	COG1846	Transcriptional regulator
MUW98_15400	COG0033	Phosphoglucomutase
MUW98_15405	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
MUW98_15410	COG0596	Alpha beta hydrolase
MUW98_15425	COG0716	FMN binding
MUW98_15435	COG0735	belongs to the Fur family
MUW98_15440	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
MUW98_15450	COG2190	(PTS) system
MUW98_15450	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
MUW98_15450	COG1263	PTS System
MUW98_15455	COG0363	glucosamine-6-phosphate deaminase activity
MUW98_15460	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
MUW98_15465	COG1846	Transcriptional regulator
MUW98_15465	COG1940	carbohydrate kinase activity
MUW98_15470	COG2194	sulfuric ester hydrolase activity
MUW98_15475	COG0217	transcriptional regulatory protein
MUW98_15480	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
MUW98_15485	COG1801	Protein of unknown function DUF72
MUW98_15490	COG4106	trans-aconitate 2-methyltransferase activity
MUW98_15495	COG0500	methyltransferase
MUW98_15515	COG0450	alkyl hydroperoxide reductase
MUW98_15520	COG0583	DNA-binding transcription factor activity
MUW98_15530	COG4584	PFAM Integrase catalytic
MUW98_15535	COG1484	DNA-dependent DNA replication
MUW98_15545	COG0791	NLP P60 protein
MUW98_15560	COG1309	transcriptional regulator
MUW98_15600	COG0534	Mate efflux family protein
MUW98_15620	COG1013	pyruvate-flavodoxin oxidoreductase activity
MUW98_15620	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
MUW98_15620	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
MUW98_15620	COG0674	pyruvate-flavodoxin oxidoreductase activity
MUW98_15630	COG0633	Ferredoxin
MUW98_15630	COG3217	Mosc domain protein beta barrel domain protein
MUW98_15630	COG0633	Ferredoxin
MUW98_15630	COG3217	Mosc domain protein beta barrel domain protein
MUW98_15640	COG0501	Belongs to the peptidase M48B family
MUW98_15645	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
MUW98_15650	COG1073	alpha beta
MUW98_15650	COG2226	methyltransferase
MUW98_15655	COG0156	8-amino-7-oxononanoate synthase activity
MUW98_15660	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
MUW98_15680	COG0017	Asparaginyl-tRNA synthetase
MUW98_15685	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
MUW98_15700	COG3069	C4-dicarboxylate transmembrane transporter activity
MUW98_15710	COG0583	DNA-binding transcription factor activity
MUW98_15715	COG1393	Belongs to the ArsC family
MUW98_15720	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
MUW98_15725	COG1876	peptidase activity
MUW98_15735	COG3263	regulation of cellular component size
MUW98_15755	COG1280	lysine exporter protein (LysE YggA)
MUW98_15785	COG0564	pseudouridine synthase activity
MUW98_15795	COG1454	alcohol dehydrogenase
MUW98_15800	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
MUW98_15805	COG0702	epimerase
MUW98_15810	COG2914	Belongs to the UPF0125 (RnfH) family
MUW98_15815	COG2867	negative regulation of translational initiation
MUW98_15820	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
MUW98_15830	COG0582	viral genome integration into host DNA
MUW98_15835	COG2916	Histone family protein nucleoid-structuring protein H-NS
MUW98_15845	COG3328	transposase activity
MUW98_15850	COG4983	Phage plasmid primase, P4 family domain protein
MUW98_15870	COG4683	PFAM Phage derived protein Gp49-like (DUF891)
MUW98_15880	COG5377	YqaJ viral recombinase family
MUW98_15925	COG2003	Belongs to the UPF0758 family
MUW98_15930	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
MUW98_15955	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
MUW98_15995	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
MUW98_16010	COG0514	ATP-dependent DNA helicase (RecQ)
MUW98_16015	COG1940	carbohydrate kinase activity
MUW98_16020	COG0583	DNA-binding transcription factor activity
MUW98_16030	COG3048	D-serine ammonia-lyase activity
MUW98_16040	COG0538	isocitrate dehydrogenase activity
MUW98_16045	COG2207	Transcriptional regulator
MUW98_16050	COG1482	cell wall glycoprotein biosynthetic process
MUW98_16065	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
MUW98_16075	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
MUW98_16080	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
MUW98_16080	COG1263	PTS System
MUW98_16085	COG1609	Transcriptional regulator
MUW98_16095	COG0789	Transcriptional regulator
MUW98_16100	COG1484	DNA-dependent DNA replication
MUW98_16105	COG4584	PFAM Integrase catalytic
MUW98_16135	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
MUW98_16135	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
MUW98_16135	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
MUW98_16145	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
MUW98_16155	COG1187	pseudouridine synthase activity
MUW98_16165	COG0482	sulfurtransferase activity
MUW98_16170	COG2915	High frequency lysogenization protein hflD homolog
MUW98_16175	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
MUW98_16180	COG2850	peptidyl-arginine hydroxylation
MUW98_16190	COG3153	acetyltransferase
MUW98_16200	COG0625	glutathione transferase activity
MUW98_16205	COG0259	pyridoxamine-phosphate oxidase activity
MUW98_16220	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
MUW98_16220	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
MUW98_16225	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
MUW98_16240	COG4235	cytochrome complex assembly
MUW98_16240	COG3088	subunit of a heme lyase
MUW98_16245	COG3088	subunit of a heme lyase
MUW98_16245	COG4235	cytochrome complex assembly
MUW98_16250	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
MUW98_16255	COG1138	Cytochrome C-type biogenesis protein
MUW98_16260	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
MUW98_16265	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
MUW98_16270	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
MUW98_16275	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
MUW98_16290	COG0835	chemotaxis
MUW98_16300	COG1192	Involved in chromosome partitioning
MUW98_16305	COG1360	Flagellar Motor Protein
MUW98_16310	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
MUW98_16315	COG2201	protein-glutamate methylesterase activity
MUW98_16320	COG0643	Histidine kinase
MUW98_16320	COG0784	Response regulator, receiver
MUW98_16320	COG2198	Histidine kinase
MUW98_16325	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
MUW98_16350	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
MUW98_16360	COG1684	flagellar biosynthetic protein fliR
MUW98_16415	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
MUW98_16425	COG1677	Flagellar hook-basal body complex protein FliE
MUW98_16440	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
MUW98_16450	COG1073	alpha beta
MUW98_16450	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
MUW98_16450	COG3064	Membrane
MUW98_16455	COG2994	toxin metabolic process
MUW98_16465	COG2274	protein secretion by the type I secretion system
MUW98_16475	COG2274	protein secretion by the type I secretion system
MUW98_16495	COG1737	Transcriptional regulator
MUW98_16500	COG0469	pyruvate kinase activity
MUW98_16510	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
MUW98_16515	COG1960	acyl-CoA dehydrogenase activity
MUW98_16525	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
MUW98_16535	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
MUW98_16555	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
MUW98_16565	COG1401	restriction endodeoxyribonuclease activity
MUW98_16570	COG0732	type I restriction modification DNA specificity domain
MUW98_16575	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
MUW98_16625	COG2003	Belongs to the UPF0758 family
MUW98_16670	COG5377	YqaJ viral recombinase family
MUW98_16690	COG4983	Phage plasmid primase, P4 family domain protein
MUW98_16740	COG0789	Transcriptional regulator
MUW98_16745	COG2916	Histone family protein nucleoid-structuring protein H-NS
MUW98_16770	COG1484	DNA-dependent DNA replication
MUW98_16775	COG4584	PFAM Integrase catalytic
MUW98_16790	COG0243	molybdopterin cofactor binding
MUW98_16795	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
MUW98_16800	COG0583	DNA-binding transcription factor activity
MUW98_16840	COG1454	alcohol dehydrogenase
MUW98_16840	COG1012	belongs to the aldehyde dehydrogenase family
MUW98_16850	COG1454	alcohol dehydrogenase
MUW98_16850	COG1012	belongs to the aldehyde dehydrogenase family
MUW98_16855	COG1882	Formate acetyltransferase
MUW98_16860	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
MUW98_16870	COG4869	propanediol catabolic process
MUW98_16890	COG5002	protein histidine kinase activity
MUW98_16895	COG0745	RESPONSE REGULATOR receiver
MUW98_16900	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
MUW98_16905	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
MUW98_16915	COG1388	LysM domain
MUW98_16915	COG1376	ErfK ybiS ycfS ynhG family protein
MUW98_16930	COG3129	Specifically methylates the adenine in position 1618 of 23S rRNA
MUW98_16935	COG0791	NLP P60 protein
MUW98_16940	COG2091	lysine biosynthetic process via aminoadipic acid
MUW98_16945	COG3118	belongs to the thioredoxin family
MUW98_16955	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
MUW98_16960	COG0788	formyltetrahydrofolate deformylase activity
MUW98_16970	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
MUW98_16990	COG0366	Alpha amylase catalytic
MUW98_16995	COG0741	lytic transglycosylase activity
MUW98_16995	COG0739	heme binding
MUW98_16995	COG1196	nuclear chromosome segregation
MUW98_17000	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
MUW98_17005	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
MUW98_17010	COG0673	inositol 2-dehydrogenase activity
MUW98_17030	COG3152	Membrane
MUW98_17050	COG1032	radical SAM domain protein
MUW98_17060	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
MUW98_17065	COG1566	PFAM secretion protein HlyD family protein
MUW98_17075	COG1752	Esterase of the alpha-beta hydrolase superfamily
MUW98_17080	COG0733	neurotransmitter:sodium symporter activity
MUW98_17110	COG0281	malic enzyme
MUW98_17120	COG0534	Mate efflux family protein
MUW98_17135	COG2233	PERMEase
MUW98_17140	COG0095	Lipoate-protein ligase
MUW98_17145	COG1115	amino acid carrier protein
MUW98_17150	COG0019	diaminopimelate decarboxylase activity
MUW98_17160	COG0678	peroxiredoxin activity
MUW98_17170	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
MUW98_17190	COG1131	(ABC) transporter
MUW98_17195	COG0545	Peptidyl-prolyl cis-trans isomerase
MUW98_17205	COG3142	Participates in the control of copper homeostasis
MUW98_17230	COG5002	protein histidine kinase activity
MUW98_17235	COG0745	RESPONSE REGULATOR receiver
MUW98_17240	COG0346	lactoylglutathione lyase activity
MUW98_17245	COG1804	L-carnitine dehydratase bile acid-inducible protein F
MUW98_17250	COG1960	acyl-CoA dehydrogenase activity
MUW98_17255	COG3284	Transcriptional regulator
MUW98_17270	COG0697	spore germination
MUW98_17275	COG4565	transcriptional regulatory protein
MUW98_17280	COG3290	protein histidine kinase activity
MUW98_17285	COG0281	malic enzyme
MUW98_17300	COG1846	Transcriptional regulator
MUW98_17305	COG1566	PFAM secretion protein HlyD family protein
MUW98_17335	COG0602	queuosine metabolic process
MUW98_17340	COG1328	CTP reductase activity
MUW98_17350	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
MUW98_17355	COG3115	cell septum assembly
MUW98_17360	COG1196	nuclear chromosome segregation
MUW98_17370	COG2860	membrane
MUW98_17380	COG3108	Peptidase M15
MUW98_17385	COG2989	Protein conserved in bacteria
MUW98_17400	COG0463	Glycosyl transferase, family 2
MUW98_17415	COG0366	Alpha amylase catalytic
MUW98_17450	COG3706	GGDEF domain
MUW98_17455	COG0037	tRNA processing
MUW98_17460	COG3590	peptidase
MUW98_17470	COG0488	(ABC) transporter
MUW98_17480	COG0531	amino acid
MUW98_17490	COG1073	alpha beta
MUW98_17495	COG1073	alpha beta
MUW98_17505	COG1234	tRNA 3'-trailer cleavage
MUW98_17510	COG0814	amino acid
MUW98_17525	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
MUW98_17530	COG1982	Orn Lys Arg decarboxylase major
MUW98_17535	COG0531	amino acid
MUW98_17540	COG3710	Transcriptional regulator
MUW98_17545	COG0825	malonyl-CoA metabolic process
MUW98_17555	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
MUW98_17560	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
MUW98_17565	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
MUW98_17570	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
MUW98_17575	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
MUW98_17590	COG0750	zinc metalloprotease
MUW98_17595	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
MUW98_17600	COG0575	Belongs to the CDS family
MUW98_17605	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
MUW98_17610	COG0233	cytoplasmic translational termination
MUW98_17615	COG0528	UMP kinase activity
MUW98_17620	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
MUW98_17625	COG0052	Belongs to the universal ribosomal protein uS2 family
MUW98_17630	COG0024	Methionine aminopeptidase
MUW98_17635	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
MUW98_17640	COG2171	N-acyltransferase activity
MUW98_17650	COG1263	PTS System
MUW98_17650	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
MUW98_17660	COG4580	involved in the transport of maltose and maltodextrins
MUW98_17670	COG0564	pseudouridine synthase activity
MUW98_17675	COG3098	single-species biofilm formation
MUW98_17700	COG5595	Zn-ribbon-containing, possibly nucleic-acid-binding protein (DUF2310)
MUW98_17710	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
MUW98_17710	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
MUW98_17725	COG1611	Belongs to the LOG family
MUW98_17730	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
MUW98_17735	COG0473	3-isopropylmalate dehydrogenase activity
MUW98_17745	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
MUW98_17750	COG2363	Small membrane protein
MUW98_17760	COG0583	DNA-binding transcription factor activity
MUW98_17765	COG0840	transmembrane signaling receptor activity
MUW98_17770	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
MUW98_17785	COG1477	protein flavinylation
MUW98_17790	COG2871	sodium ion transport
MUW98_17795	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
MUW98_17800	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
MUW98_17805	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
MUW98_17810	COG1805	sodium ion transport
MUW98_17815	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
MUW98_17820	COG0271	Belongs to the BolA IbaG family
MUW98_17825	COG2813	Specifically methylates the guanine in position
MUW98_17835	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
MUW98_17845	COG2211	Major facilitator Superfamily
MUW98_17850	COG3248	Nucleoside-binding outer membrane protein
MUW98_17855	COG1666	GTP binding
MUW98_17860	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
MUW98_17865	COG0693	protein deglycase activity
MUW98_17910	COG3501	Rhs element vgr protein
MUW98_17925	COG2771	luxR family
MUW98_17935	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
MUW98_17935	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
MUW98_17940	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
MUW98_17950	COG1151	hydroxylamine reductase activity
MUW98_17955	COG0783	Belongs to the Dps family
MUW98_17980	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
MUW98_17995	COG4221	oxidoreductase activity
MUW98_18005	COG0415	Belongs to the DNA photolyase family
MUW98_18010	COG0789	Transcriptional regulator
MUW98_18015	COG3272	Protein of unknown function (DUF1722)
MUW98_18045	COG0077	Prephenate dehydratase
MUW98_18045	COG1605	Chorismate mutase
MUW98_18080	COG0840	transmembrane signaling receptor activity
MUW98_18090	COG0300	oxidoreductase activity
MUW98_18115	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
MUW98_18140	COG0826	peptidase U32
MUW98_18145	COG1280	lysine exporter protein (LysE YggA)
MUW98_18155	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
MUW98_18160	COG0840	transmembrane signaling receptor activity
MUW98_18175	COG2198	Histidine kinase
MUW98_18175	COG0643	Histidine kinase
MUW98_18185	COG0835	chemotaxis
MUW98_18190	COG0840	transmembrane signaling receptor activity
MUW98_18200	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
MUW98_18205	COG2201	protein-glutamate methylesterase activity
MUW98_18210	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
MUW98_18240	COG2197	response regulator
MUW98_18250	COG3188	usher protein
MUW98_18270	COG2199	diguanylate cyclase activity
MUW98_18270	COG2200	EAL domain
MUW98_18270	COG2203	Gaf domain
MUW98_18275	COG0826	peptidase U32
MUW98_18280	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
MUW98_18290	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
MUW98_18305	COG2200	EAL domain
MUW98_18310	COG0737	Belongs to the 5'-nucleotidase family
MUW98_18330	COG2204	response regulator
MUW98_18335	COG0545	Peptidyl-prolyl cis-trans isomerase
MUW98_18350	COG1047	Peptidyl-prolyl cis-trans
MUW98_18355	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
MUW98_18365	COG0835	chemotaxis
MUW98_18365	COG0784	Response regulator, receiver
MUW98_18370	COG0429	hydrolase of the alpha beta-hydrolase fold
MUW98_18375	COG4251	negative regulation of phosphorylation
MUW98_18375	COG3706	GGDEF domain
MUW98_18375	COG2203	Gaf domain
MUW98_18375	COG5001	Diguanylate cyclase
MUW98_18380	COG3089	Belongs to the UPF0270 family
MUW98_18390	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
MUW98_18395	COG0463	Glycosyl transferase, family 2
MUW98_18400	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
MUW98_18400	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
MUW98_18405	COG0726	polysaccharide deacetylase
MUW98_18410	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
MUW98_18415	COG2076	Multidrug Resistance protein
MUW98_18420	COG2076	Multidrug Resistance protein
MUW98_18425	COG3954	Phosphoribulokinase
MUW98_18440	COG1765	OsmC-like protein
MUW98_18450	COG2226	methyltransferase
MUW98_18455	COG3397	chitin binding
MUW98_18470	COG2202	Pas domain
MUW98_18470	COG2205	protein histidine kinase activity
MUW98_18480	COG3655	Transcriptional regulator
MUW98_18485	COG2814	Major facilitator Superfamily
MUW98_18490	COG4771	TonB-dependent receptor
MUW98_18510	COG0748	coenzyme F420 binding
MUW98_18515	COG3721	Heme iron utilization protein
MUW98_18525	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MUW98_18550	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
MUW98_18555	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
MUW98_18560	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
MUW98_18580	COG0741	lytic transglycosylase activity
MUW98_18585	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
MUW98_18600	COG0488	(ABC) transporter
MUW98_18610	COG2252	PERMEase
MUW98_18615	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
MUW98_18620	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
MUW98_18625	COG3178	'Phosphotransferase
MUW98_18630	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
MUW98_18640	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
MUW98_18645	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
MUW98_18650	COG2967	ApaG domain
MUW98_18655	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
MUW98_18665	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MUW98_18670	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
MUW98_18685	COG0318	PFAM AMP-dependent synthetase and ligase
MUW98_18690	COG3314	Sporulation integral membrane protein YlbJ
MUW98_18695	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
MUW98_18700	COG0211	Belongs to the bacterial ribosomal protein bL27 family
MUW98_18705	COG0261	This protein binds to 23S rRNA in the presence of protein L20
MUW98_18710	COG0142	geranyltranstransferase activity
MUW98_18715	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
MUW98_18720	COG0330	HflC and HflK could
MUW98_18725	COG0330	HflC and HflK could
MUW98_18730	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
MUW98_18735	COG1923	regulation of RNA biosynthetic process
MUW98_18740	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
MUW98_18745	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
MUW98_18755	COG0802	atpase or kinase
MUW98_18760	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
MUW98_18760	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
MUW98_18765	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
MUW98_18780	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
MUW98_18785	COG2011	ABC-type metal ion transport system permease component
MUW98_18790	COG1464	Belongs to the NlpA lipoprotein family
MUW98_18800	COG0840	transmembrane signaling receptor activity
MUW98_18825	COG5002	protein histidine kinase activity
MUW98_18825	COG2198	Histidine kinase
MUW98_18825	COG0784	Response regulator, receiver
MUW98_18845	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
MUW98_18860	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
MUW98_18865	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
MUW98_18875	COG2716	regulation of RNA biosynthetic process
MUW98_18880	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
MUW98_18885	COG3013	Belongs to the UPF0304 family
MUW98_18895	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
MUW98_18900	COG0280	phosphate acetyltransferase
MUW98_18900	COG0857	belongs to the CobB CobQ family
MUW98_18910	COG0028	Belongs to the TPP enzyme family
MUW98_18920	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
MUW98_18925	COG0671	phosphoesterase, PA-phosphatase related
MUW98_18935	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
MUW98_18940	COG0473	3-isopropylmalate dehydrogenase activity
MUW98_18945	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
MUW98_18950	COG0066	3-isopropylmalate dehydratase activity
MUW98_18965	COG4143	(ABC) transporter
MUW98_18970	COG1178	ABC-type Fe3 transport system permease component
MUW98_18975	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
MUW98_18985	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
MUW98_18995	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MUW98_19025	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
MUW98_19030	COG0564	pseudouridine synthase activity
MUW98_19040	COG5001	Diguanylate cyclase
MUW98_19040	COG3300	MHYT domain
MUW98_19050	COG0459	protein refolding
MUW98_19055	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
MUW98_19060	COG0534	Mate efflux family protein
MUW98_19065	COG3030	protein affecting phage T7 exclusion by the F plasmid
MUW98_19070	COG1027	Aspartate ammonia-lyase
MUW98_19075	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
MUW98_19085	COG0477	Major facilitator Superfamily
MUW98_19100	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
MUW98_19105	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
MUW98_19115	COG0673	inositol 2-dehydrogenase activity
MUW98_19125	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
MUW98_19130	COG0635	Involved in the biosynthesis of porphyrin-containing compound
MUW98_19135	COG3036	rescue of stalled ribosome
MUW98_19140	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
MUW98_19150	COG0138	bifunctional purine biosynthesis protein purh
MUW98_19155	COG0151	Belongs to the GarS family
MUW98_19180	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
MUW98_19185	COG0358	DNA primase activity
MUW98_19190	COG1610	YqeY-like protein
MUW98_19195	COG0828	Belongs to the bacterial ribosomal protein bS21 family
MUW98_19200	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
MUW98_19215	COG1238	metal cluster binding
MUW98_19220	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
MUW98_19225	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
MUW98_19230	COG0585	pseudouridine synthase activity
MUW98_19240	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
MUW98_19245	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
MUW98_19250	COG0148	phosphopyruvate hydratase activity
MUW98_19255	COG0504	CTP synthase activity
MUW98_19260	COG3956	TIGRFAM MazG family protein
MUW98_19265	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
MUW98_19270	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
MUW98_19280	COG4807	Protein conserved in bacteria
MUW98_19285	COG3023	N-Acetylmuramoyl-L-alanine amidase
MUW98_19290	COG1349	DNA-binding transcription factor activity
MUW98_19300	COG2222	sugar isomerase
MUW98_19305	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
MUW98_19315	COG3716	PTS system mannose fructose sorbose family IID component
MUW98_19320	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
MUW98_19325	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
MUW98_19340	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
MUW98_19345	COG1381	Involved in DNA repair and RecF pathway recombination
MUW98_19355	COG0571	ribonuclease III activity
MUW98_19360	COG0681	Belongs to the peptidase S26 family
MUW98_19365	COG0481	GTPase activity
MUW98_19380	COG3073	An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E
MUW98_19385	COG1595	DNA-templated transcription, initiation
MUW98_19390	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
MUW98_19400	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
MUW98_19440	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
MUW98_19450	COG0126	phosphoglycerate kinase activity
MUW98_19455	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
MUW98_19460	COG1940	carbohydrate kinase activity
MUW98_19465	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
MUW98_19480	COG4991	sh3 domain protein
MUW98_19485	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
MUW98_19500	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
MUW98_19520	COG1505	serine-type exopeptidase activity
MUW98_19525	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
MUW98_19530	COG0765	amino acid transport
MUW98_19535	COG0765	amino acid transport
MUW98_19540	COG1126	abc transporter atp-binding protein
MUW98_19545	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
MUW98_19550	COG0577	efflux transmembrane transporter activity
MUW98_19550	COG1136	(ABC) transporter
MUW98_19555	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
MUW98_19560	COG0745	RESPONSE REGULATOR receiver
MUW98_19565	COG2205	protein histidine kinase activity
MUW98_19570	COG2816	NAD+ diphosphatase activity
MUW98_19605	COG2070	2-Nitropropane dioxygenase
MUW98_19630	COG1858	cytochrome C peroxidase
MUW98_19635	COG1912	Pfam S-adenosyl-l-methionine hydroxide adenosyltransferase
MUW98_19660	COG0513	Belongs to the DEAD box helicase family
MUW98_19680	COG0154	amidase activity
MUW98_19685	COG2957	Belongs to the agmatine deiminase family
MUW98_19695	COG2852	Protein conserved in bacteria
MUW98_19705	COG1902	pentaerythritol trinitrate reductase activity
MUW98_19740	COG5001	Diguanylate cyclase
MUW98_19740	COG3300	MHYT domain
MUW98_19750	COG0714	Associated with various cellular activities
MUW98_19760	COG0456	acetyltransferase
MUW98_19770	COG1022	Amp-dependent synthetase and ligase
MUW98_19775	COG2918	glutathione biosynthetic process
MUW98_19780	COG0612	Peptidase, M16
MUW98_19785	COG1238	metal cluster binding
MUW98_19810	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
MUW98_19815	COG0359	binds to the 23S rRNA
MUW98_19820	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
MUW98_19825	COG0360	Binds together with S18 to 16S ribosomal RNA
MUW98_19830	COG1914	H( )-stimulated, divalent metal cation uptake system
MUW98_19850	COG2153	protein acetylation
MUW98_19860	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
MUW98_19865	COG0557	exoribonuclease II activity
MUW98_19870	COG3706	GGDEF domain
MUW98_19875	COG1854	S-ribosylhomocysteine lyase activity
MUW98_19890	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
MUW98_19890	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
MUW98_19940	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
MUW98_19945	COG1047	Peptidyl-prolyl cis-trans
MUW98_19950	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
MUW98_19955	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
MUW98_19960	COG0196	riboflavin kinase activity
MUW98_19970	COG0728	peptidoglycan biosynthetic process
MUW98_19975	COG0268	Binds directly to 16S ribosomal RNA
MUW98_19980	COG0640	Transcriptional regulator
MUW98_19985	COG0583	DNA-binding transcription factor activity
MUW98_19995	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
MUW98_20000	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
MUW98_20005	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
MUW98_20015	COG1051	belongs to the nudix hydrolase family
MUW98_20020	COG3066	DNA modification
MUW98_20030	COG0335	large ribosomal subunit rRNA binding
MUW98_20035	COG0336	Belongs to the RNA methyltransferase TrmD family
MUW98_20040	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
MUW98_20045	COG0228	four-way junction DNA binding
MUW98_20050	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
MUW98_20055	COG4137	Cytochrome C assembly protein
MUW98_20060	COG4536	flavin adenine dinucleotide binding
MUW98_20065	COG1959	2 iron, 2 sulfur cluster binding
MUW98_20070	COG1017	nitric oxide dioxygenase activity
MUW98_20070	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
MUW98_20075	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
MUW98_20080	COG0039	L-malate dehydrogenase activity
MUW98_20085	COG4160	amino acid transport
MUW98_20090	COG4215	(ABC) transporter
MUW98_20095	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
MUW98_20100	COG1126	abc transporter atp-binding protein
MUW98_20105	COG1438	arginine binding
MUW98_20110	COG2837	iron assimilation
MUW98_20115	COG3842	ATPase activity
MUW98_20125	COG1840	ABC-type Fe3 transport system, periplasmic component
MUW98_20130	COG0347	Belongs to the P(II) protein family
MUW98_20145	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
MUW98_20150	COG0583	DNA-binding transcription factor activity
MUW98_20165	COG1929	Belongs to the glycerate kinase type-1 family
MUW98_20170	COG2610	gluconate transmembrane transporter activity
MUW98_20175	COG3835	regulator
MUW98_20185	COG3112	Uncharacterised protein family (UPF0231)
MUW98_20200	COG0840	transmembrane signaling receptor activity
MUW98_20220	COG0513	Belongs to the DEAD box helicase family
MUW98_20260	COG1448	Aminotransferase
MUW98_20275	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
MUW98_20280	COG1328	CTP reductase activity
MUW98_20300	COG0793	Belongs to the peptidase S41A family
MUW98_20300	COG4946	Tricorn protease homolog
MUW98_20335	COG3397	chitin binding
MUW98_20340	COG0583	DNA-binding transcription factor activity
MUW98_20345	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
MUW98_20350	COG4208	sulfate ABC transporter
MUW98_20355	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
MUW98_20365	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
MUW98_20370	COG3174	membrane
MUW98_20375	COG0110	maltose O-acetyltransferase activity
MUW98_20400	COG0165	Argininosuccinate lyase
MUW98_20405	COG0137	argininosuccinate synthase activity
MUW98_20415	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
MUW98_20420	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
MUW98_20430	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
MUW98_20435	COG0460	homoserine dehydrogenase
MUW98_20435	COG0527	aspartate kinase activity
MUW98_20440	COG0626	cystathionine gamma-synthase activity
MUW98_20450	COG2207	Transcriptional regulator
MUW98_20450	COG3708	Transcriptional regulator
MUW98_20455	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
MUW98_20460	COG0814	amino acid
MUW98_20465	COG1218	3'(2'),5'-bisphosphate nucleotidase
MUW98_20470	COG0494	nUDIX hydrolase
MUW98_20475	COG1011	Hydrolase
MUW98_20480	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
MUW98_20495	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
MUW98_20505	COG3156	type II secretion system protein K
MUW98_20510	COG4795	General secretion pathway protein
MUW98_20515	COG2165	general secretion pathway protein
MUW98_20530	COG2165	general secretion pathway protein
MUW98_20535	COG1459	type II secretion system
MUW98_20540	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
MUW98_20550	COG3031	protein transport across the cell outer membrane
MUW98_20560	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
MUW98_20565	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
MUW98_20585	COG0456	acetyltransferase
MUW98_20590	COG3133	Outer membrane lipoprotein
MUW98_20605	COG2771	luxR family
MUW98_20610	COG3916	Acyl-homoserine-lactone synthase
MUW98_20620	COG4776	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction
MUW98_20625	COG1309	transcriptional regulator
MUW98_20635	COG2213	PTS system mannitol-specific
MUW98_20635	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
MUW98_20640	COG0246	Mannitol dehydrogenase
MUW98_20645	COG3722	fumarate hydratase activity
MUW98_20650	COG3263	regulation of cellular component size
MUW98_20675	COG1671	Belongs to the UPF0178 family
MUW98_20690	COG1988	membrane-bound metal-dependent
MUW98_20695	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
MUW98_20705	COG0513	Belongs to the DEAD box helicase family
MUW98_20730	COG1575	Belongs to the MenA family. Type 1 subfamily
MUW98_20735	COG1169	isochorismate synthase
MUW98_20740	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
MUW98_20745	COG0596	Alpha beta hydrolase
MUW98_20750	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
MUW98_20755	COG1441	menaquinone biosynthetic process
MUW98_20760	COG0318	PFAM AMP-dependent synthetase and ligase
MUW98_20770	COG3328	transposase activity
MUW98_20785	COG3539	Fimbrial protein
MUW98_20790	COG3121	Chaperone
MUW98_20795	COG3188	usher protein
MUW98_20805	COG3539	Fimbrial protein
MUW98_20815	COG3291	Pkd domain containing protein
MUW98_20820	COG2949	membrane
MUW98_20825	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
MUW98_20835	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
MUW98_20840	COG5380	lipid catabolic process
MUW98_20855	COG4533	DNA binding
MUW98_20865	COG2873	o-acetylhomoserine
MUW98_20875	COG1979	alcohol dehydrogenase
MUW98_20895	COG4221	oxidoreductase activity
MUW98_20915	COG1285	pathogenesis
MUW98_20935	COG1368	sulfuric ester hydrolase activity
MUW98_20940	COG1522	sequence-specific DNA binding
MUW98_20950	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
MUW98_20955	COG1418	mRNA catabolic process
MUW98_20960	COG1058	Belongs to the CinA family
MUW98_20960	COG1546	Belongs to the CinA family
MUW98_20970	COG1129	ABC transporter
MUW98_20970	COG0842	Transport permease protein
MUW98_20985	COG0561	phosphatase activity
MUW98_20990	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
MUW98_21010	COG1011	Hydrolase
MUW98_21025	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
MUW98_21030	COG0019	diaminopimelate decarboxylase activity
MUW98_21040	COG1965	Belongs to the frataxin family
MUW98_21045	COG0400	carboxylic ester hydrolase activity
MUW98_21050	COG3072	Adenylate cyclase
MUW98_21055	COG0181	hydroxymethylbilane synthase activity
MUW98_21065	COG2959	enzyme of heme biosynthesis
MUW98_21080	COG1494	fructose-1,6-bisphosphatase
MUW98_21120	COG1733	regulation of RNA biosynthetic process
MUW98_21140	COG3932	Exopolysaccharide synthesis, ExoD
MUW98_21145	COG0814	amino acid
MUW98_21150	COG3706	GGDEF domain
MUW98_21170	COG3417	Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1B (PBP1b)
MUW98_21185	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
MUW98_21190	COG2022	thiamine diphosphate biosynthetic process
MUW98_21200	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
MUW98_21205	COG0352	thiamine-phosphate diphosphorylase activity
MUW98_21210	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
MUW98_21235	COG0745	RESPONSE REGULATOR receiver
MUW98_21240	COG0642	Histidine kinase
MUW98_21250	COG0189	ligase activity
MUW98_21275	COG1639	'signal transduction protein
MUW98_21285	COG2321	neutral zinc metallopeptidase
MUW98_21290	COG3700	Belongs to the class B bacterial acid phosphatase family
MUW98_21310	COG1366	Belongs to the anti-sigma-factor antagonist family
MUW98_21315	COG2172	sigma factor antagonist activity
MUW98_21320	COG0784	Response regulator, receiver
MUW98_21320	COG2205	protein histidine kinase activity
MUW98_21320	COG5002	protein histidine kinase activity
MUW98_21325	COG3437	response regulator, receiver
MUW98_21335	COG0477	Major facilitator Superfamily
MUW98_21350	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
MUW98_21355	COG1263	PTS System
MUW98_21355	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
MUW98_21375	COG0312	modulator of DNA gyrase
MUW98_21380	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
MUW98_21390	COG3164	Protein of unknown function
MUW98_21395	COG1530	ribonuclease E activity
MUW98_21400	COG0424	maF-like protein
MUW98_21405	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
MUW98_21410	COG1792	Involved in formation and maintenance of cell shape
MUW98_21415	COG1077	Cell shape determining protein MreB Mrl
MUW98_21450	COG2165	general secretion pathway protein
MUW98_21460	COG1459	type II secretion system
MUW98_21465	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
MUW98_21510	COG2199	diguanylate cyclase activity
MUW98_21510	COG2200	EAL domain
MUW98_21515	COG2200	EAL domain
MUW98_21520	COG0387	Pfam Sodium calcium exchanger
MUW98_21525	COG2986	histidine ammonia-lyase
MUW98_21530	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
MUW98_21535	COG0010	Belongs to the arginase family
MUW98_21540	COG1228	amidohydrolase
MUW98_21545	COG2188	Transcriptional regulator
MUW98_21550	COG0288	reversible hydration of carbon dioxide
MUW98_21560	COG2177	Part of the ABC transporter FtsEX involved in
MUW98_21565	COG2884	Cell division ATP-binding protein ftsE
MUW98_21570	COG0552	protein localization to endoplasmic reticulum
MUW98_21575	COG0742	ribosomal rna small subunit methyltransferase
MUW98_21600	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
MUW98_21610	COG0741	lytic transglycosylase activity
MUW98_21620	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
MUW98_21630	COG2095	MarC family integral membrane protein
MUW98_21640	COG1301	dicarboxylic acid transport
MUW98_21665	COG3714	YhhN family
MUW98_21685	COG1770	oligopeptidase
MUW98_21700	COG4221	oxidoreductase activity
MUW98_21705	COG0583	DNA-binding transcription factor activity
MUW98_21710	COG2249	NAD(P)H dehydrogenase (quinone) activity
MUW98_21760	COG0203	ribosomal protein L17
MUW98_21765	COG0202	RNA polymerase activity
MUW98_21770	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
MUW98_21775	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
MUW98_21780	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
MUW98_21785	COG0257	Belongs to the bacterial ribosomal protein bL36 family
MUW98_21790	COG0201	protein transport
MUW98_21795	COG0200	Binds to the 23S rRNA
MUW98_21800	COG1841	ribosomal large subunit assembly
MUW98_21805	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
MUW98_21810	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
MUW98_21815	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
MUW98_21820	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
MUW98_21825	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
MUW98_21830	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
MUW98_21835	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
MUW98_21840	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
MUW98_21845	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
MUW98_21850	COG0255	Belongs to the universal ribosomal protein uL29 family
MUW98_21855	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
MUW98_21860	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
MUW98_21865	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
MUW98_21870	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
MUW98_21875	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
MUW98_21880	COG0089	rRNA binding
MUW98_21885	COG0088	Forms part of the polypeptide exit tunnel
MUW98_21890	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
MUW98_21895	COG0051	transcription antitermination factor activity, RNA binding
MUW98_21915	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
MUW98_21920	COG2183	response to ionizing radiation
MUW98_21940	COG0596	Alpha beta hydrolase
MUW98_21945	COG1040	competence protein
MUW98_21950	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
MUW98_21950	COG0316	Belongs to the HesB IscA family
MUW98_21955	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
MUW98_21960	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
MUW98_21965	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
MUW98_21970	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
MUW98_21975	COG4942	peptidase
MUW98_21985	COG1609	Transcriptional regulator
MUW98_21990	COG0800	Aldolase
MUW98_22000	COG3265	gluconokinase activity
MUW98_22005	COG2610	gluconate transmembrane transporter activity
MUW98_22010	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
MUW98_22015	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
MUW98_22025	COG0456	acetyltransferase
MUW98_22035	COG1490	D-aminoacyl-tRNA deacylase activity
MUW98_22045	COG1295	ribonuclease BN
MUW98_22050	COG1217	gtp-binding protein TYPA
MUW98_22055	COG0174	glutamine synthetase
MUW98_22065	COG3852	Histidine kinase
MUW98_22070	COG2204	response regulator
MUW98_22075	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
MUW98_22080	COG0635	Involved in the biosynthesis of porphyrin-containing compound
MUW98_22090	COG3078	GTPase activator activity
MUW98_22100	COG0218	Necessary for normal cell division and for the maintenance of normal septation
MUW98_22110	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
MUW98_22115	COG0408	coproporphyrinogen oxidase activity
MUW98_22120	COG0009	L-threonylcarbamoyladenylate synthase
MUW98_22130	COG0551	DNA topoisomerase type I activity
MUW98_22135	COG2922	Belongs to the Smg family
MUW98_22140	COG0758	DNA mediated transformation
MUW98_22150	COG0242	peptide deformylase activity
MUW98_22155	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
MUW98_22160	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
MUW98_22160	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
MUW98_22165	COG0569	domain protein
MUW98_22170	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
MUW98_22175	COG1322	Protein conserved in bacteria
MUW98_22195	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
MUW98_22200	COG0686	Belongs to the AlaDH PNT family
MUW98_22205	COG0518	GMP synthase (glutamine-hydrolyzing) activity
MUW98_22205	COG0519	Catalyzes the synthesis of GMP from XMP
MUW98_22215	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
MUW98_22220	COG1396	sequence-specific DNA binding
MUW98_22225	COG1012	belongs to the aldehyde dehydrogenase family
MUW98_22235	COG2962	Rard protein
MUW98_22245	COG1280	lysine exporter protein (LysE YggA)
MUW98_22255	COG0840	transmembrane signaling receptor activity
MUW98_22260	COG2391	methyltransferase activity
MUW98_22265	COG1280	lysine exporter protein (LysE YggA)
MUW98_22320	COG0583	DNA-binding transcription factor activity
MUW98_22325	COG1943	Transposase
MUW98_22345	COG0210	DNA helicase
MUW98_22360	COG1744	ABC transporter substrate-binding protein PnrA-like
MUW98_22365	COG3845	ABC transporter
MUW98_22370	COG4603	Belongs to the binding-protein-dependent transport system permease family
MUW98_22375	COG1079	Belongs to the binding-protein-dependent transport system permease family
MUW98_22380	COG0583	DNA-binding transcription factor activity
MUW98_22400	COG1262	PFAM Formylglycine-generating sulfatase enzyme
MUW98_22405	COG0385	Bile acid
MUW98_22410	COG0531	amino acid
MUW98_22415	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
MUW98_22420	COG0531	amino acid
MUW98_22425	COG2731	YhcH YjgK YiaL family protein
MUW98_22430	COG3250	beta-galactosidase activity
MUW98_22435	COG1609	Transcriptional regulator
MUW98_22470	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
MUW98_22475	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
MUW98_22475	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
MUW98_22480	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
MUW98_22485	COG3074	FtsZ-dependent cytokinesis
MUW98_22495	COG1045	serine acetyltransferase
MUW98_22505	COG0745	RESPONSE REGULATOR receiver
MUW98_22510	COG2205	protein histidine kinase activity
MUW98_22515	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
MUW98_22520	COG0534	Mate efflux family protein
MUW98_22535	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
MUW98_22540	COG2937	Belongs to the GPAT DAPAT family
MUW98_22545	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
MUW98_22550	COG3161	chorismate lyase activity
MUW98_22555	COG1580	Controls the rotational direction of flagella during chemotaxis
MUW98_22570	COG0604	alcohol dehydrogenase
MUW98_22575	COG1609	Transcriptional regulator
MUW98_22595	COG1519	Transferase
MUW98_22600	COG0859	PFAM glycosyl transferase family 9
MUW98_22605	COG0463	Glycosyl transferase, family 2
MUW98_22610	COG0859	PFAM glycosyl transferase family 9
MUW98_22615	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
MUW98_22620	COG2990	Protein conserved in bacteria
MUW98_22625	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
MUW98_22635	COG0267	Belongs to the bacterial ribosomal protein bL33 family
MUW98_22640	COG0227	Belongs to the bacterial ribosomal protein bL28 family
MUW98_22645	COG2003	Belongs to the UPF0758 family
MUW98_22650	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
MUW98_22655	COG0756	dUTP diphosphatase activity
MUW98_22660	COG1309	transcriptional regulator
MUW98_22665	COG0668	transmembrane transport
MUW98_22675	COG0166	Belongs to the GPI family
MUW98_22680	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
MUW98_22685	COG0583	DNA-binding transcription factor activity
MUW98_22700	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
MUW98_22700	COG1042	CoA-binding domain protein
MUW98_22700	COG0045	succinate-CoA ligase (ADP-forming) activity
MUW98_22730	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
MUW98_22735	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
MUW98_22740	COG1739	Uncharacterized protein family UPF0029
MUW98_22745	COG0006	proline dipeptidase activity
MUW98_22750	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
MUW98_22755	COG1024	Enoyl-CoA hydratase
MUW98_22755	COG1250	3-hydroxyacyl-CoA dehydrogenase
MUW98_22760	COG0183	Belongs to the thiolase family
MUW98_22785	COG0425	Belongs to the sulfur carrier protein TusA family
MUW98_22790	COG0251	oxidation-reduction process
MUW98_22795	COG2885	chlorophyll binding
MUW98_22805	COG2818	Glycosylase
MUW98_22810	COG0752	glycyl-tRNA synthetase alpha subunit
MUW98_22815	COG0751	glycine-tRNA ligase activity
MUW98_22830	COG0194	GDP metabolic process
MUW98_22850	COG0814	amino acid
MUW98_22855	COG0348	domain, Protein
MUW98_22865	COG0446	pyridine nucleotide-disulphide oxidoreductase
MUW98_22870	COG1773	rubredoxin
MUW98_22870	COG0426	domain, Protein
MUW98_22875	COG3604	Transcriptional regulator
MUW98_22880	COG2188	Transcriptional regulator
MUW98_22895	COG1609	Transcriptional regulator
MUW98_22935	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
MUW98_22960	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
MUW98_22975	COG3118	belongs to the thioredoxin family
MUW98_22980	COG0513	Belongs to the DEAD box helicase family
MUW98_22985	COG0248	Ppx GppA phosphatase
MUW98_22995	COG0742	ribosomal rna small subunit methyltransferase
MUW98_23015	COG0084	hydrolase, TatD family'
MUW98_23020	COG0805	protein transport
MUW98_23025	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
MUW98_23035	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
MUW98_23040	COG3165	ubiquinone biosynthetic process from chorismate
MUW98_23050	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
MUW98_23055	COG0402	S-adenosylhomocysteine deaminase activity
MUW98_23100	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
MUW98_23105	COG0848	biopolymer transport protein
MUW98_23110	COG0811	peptide transport
MUW98_23115	COG0811	peptide transport
MUW98_23125	COG2771	luxR family
MUW98_23130	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
MUW98_23135	COG1349	DNA-binding transcription factor activity
MUW98_23140	COG0745	RESPONSE REGULATOR receiver
MUW98_23145	COG2205	protein histidine kinase activity
MUW98_23155	COG4452	Inner membrane protein CreD
MUW98_23160	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
MUW98_23165	COG0355	proton-transporting ATP synthase activity, rotational mechanism
MUW98_23170	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
MUW98_23175	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
MUW98_23180	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
MUW98_23185	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
MUW98_23190	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
MUW98_23200	COG0356	it plays a direct role in the translocation of protons across the membrane
MUW98_23210	COG1475	DNA binding
MUW98_23215	COG1192	Involved in chromosome partitioning
MUW98_23220	COG0357	Ribosomal RNA small subunit methyltransferase G
MUW98_23225	COG0445	tRNA wobble uridine modification
MUW98_23230	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
MUW98_23235	COG4774	siderophore transport
MUW98_23240	COG4615	Cyclic peptide transporter
MUW98_23245	COG1120	ATPase activity
MUW98_23260	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
MUW98_23265	COG0706	membrane insertase activity
MUW98_23270	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
MUW98_23275	COG0594	ribonuclease P activity
MUW98_23280	COG0230	Belongs to the bacterial ribosomal protein bL34 family
MUW98_23285	COG1126	abc transporter atp-binding protein
MUW98_23390	COG2916	Histone family protein nucleoid-structuring protein H-NS
MUW98_23465	COG3039	Transposase
MUW98_23480	COG2197	response regulator
MUW98_23645	COG3039	Transposase
MUW98_23795	COG2916	Histone family protein nucleoid-structuring protein H-NS
MUW98_23820	COG2011	ABC-type metal ion transport system permease component
MUW98_23830	COG1464	Belongs to the NlpA lipoprotein family
MUW98_23865	COG0840	transmembrane signaling receptor activity
MUW98_23895	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
MUW98_23960	COG2003	Belongs to the UPF0758 family
MUW98_24145	COG1192	Involved in chromosome partitioning
MUW98_24200	COG2974	May be involved in recombination
MUW98_24215	COG2189	Belongs to the N(4) N(6)-methyltransferase family
MUW98_24385	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
MUW98_24415	COG2771	luxR family
MUW98_24475	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
MUW98_24505	COG2916	Histone family protein nucleoid-structuring protein H-NS
MUW98_24520	COG4962	Type ii secretion system protein e
MUW98_24600	COG3451	type IV secretory pathway VirB4
MUW98_24665	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
MUW98_24750	COG1937	Protein conserved in bacteria
MUW98_24760	COG0640	Transcriptional regulator
MUW98_24765	COG0840	transmembrane signaling receptor activity