locus-tag	class	description
HQK30_00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
HQK30_00010	COG0592	DNA-directed DNA polymerase activity
HQK30_00030	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
HQK30_00100	COG2378	regulation of single-species biofilm formation
HQK30_00105	COG0071	Belongs to the small heat shock protein (HSP20) family
HQK30_00110	COG0071	Belongs to the small heat shock protein (HSP20) family
HQK30_00115	COG3977	Valine--pyruvate aminotransferase
HQK30_00130	COG2814	Major facilitator Superfamily
HQK30_00135	COG0745	RESPONSE REGULATOR receiver
HQK30_00140	COG2205	protein histidine kinase activity
HQK30_00165	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
HQK30_00170	COG4191	Histidine kinase
HQK30_00170	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HQK30_00175	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HQK30_00180	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HQK30_00185	COG1309	transcriptional regulator
HQK30_00220	COG2271	Major facilitator Superfamily
HQK30_00240	COG0561	phosphatase activity
HQK30_00245	COG2267	carboxylic ester hydrolase activity
HQK30_00255	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HQK30_00260	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HQK30_00265	COG1758	RNA polymerase activity
HQK30_00275	COG0859	PFAM glycosyl transferase family 9
HQK30_00280	COG3642	lipopolysaccharide core region biosynthetic process
HQK30_00320	COG0589	response to stress
HQK30_00325	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
HQK30_00330	COG2199	diguanylate cyclase activity
HQK30_00335	COG1528	Iron-storage protein
HQK30_00340	COG2081	HI0933 family
HQK30_00345	COG2223	nitrite transmembrane transporter activity
HQK30_00365	COG3188	usher protein
HQK30_00385	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HQK30_00385	COG2205	protein histidine kinase activity
HQK30_00395	COG3275	phosphorelay sensor kinase activity
HQK30_00400	COG3279	Response regulator of the LytR AlgR family
HQK30_00405	COG2223	nitrite transmembrane transporter activity
HQK30_00410	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
HQK30_00415	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
HQK30_00430	COG0583	DNA-binding transcription factor activity
HQK30_00440	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
HQK30_00470	COG1042	CoA-binding domain protein
HQK30_00470	COG0045	succinate-CoA ligase (ADP-forming) activity
HQK30_00470	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HQK30_00485	COG0583	DNA-binding transcription factor activity
HQK30_00490	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
HQK30_00495	COG0166	Belongs to the GPI family
HQK30_00505	COG0668	transmembrane transport
HQK30_00510	COG1309	transcriptional regulator
HQK30_00515	COG0756	dUTP diphosphatase activity
HQK30_00520	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
HQK30_00525	COG2003	Belongs to the UPF0758 family
HQK30_00530	COG0227	Belongs to the bacterial ribosomal protein bL28 family
HQK30_00535	COG0267	Belongs to the bacterial ribosomal protein bL33 family
HQK30_00545	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
HQK30_00550	COG2990	Protein conserved in bacteria
HQK30_00555	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
HQK30_00560	COG0859	PFAM glycosyl transferase family 9
HQK30_00565	COG0463	Glycosyl transferase, family 2
HQK30_00570	COG0859	PFAM glycosyl transferase family 9
HQK30_00575	COG1519	Transferase
HQK30_00595	COG1609	Transcriptional regulator
HQK30_00600	COG0604	alcohol dehydrogenase
HQK30_00615	COG1580	Controls the rotational direction of flagella during chemotaxis
HQK30_00620	COG3161	chorismate lyase activity
HQK30_00625	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
HQK30_00630	COG2937	Belongs to the GPAT DAPAT family
HQK30_00635	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
HQK30_00650	COG0534	Mate efflux family protein
HQK30_00655	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
HQK30_00660	COG2205	protein histidine kinase activity
HQK30_00665	COG0745	RESPONSE REGULATOR receiver
HQK30_00675	COG1045	serine acetyltransferase
HQK30_00685	COG3074	FtsZ-dependent cytokinesis
HQK30_00690	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
HQK30_00695	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HQK30_00695	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HQK30_00700	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
HQK30_00735	COG1609	Transcriptional regulator
HQK30_00740	COG3250	beta-galactosidase activity
HQK30_00745	COG2731	YhcH YjgK YiaL family protein
HQK30_00750	COG0531	amino acid
HQK30_00755	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HQK30_00760	COG0531	amino acid
HQK30_00765	COG0385	Bile acid
HQK30_00770	COG1262	PFAM Formylglycine-generating sulfatase enzyme
HQK30_00790	COG0583	DNA-binding transcription factor activity
HQK30_00815	COG0210	DNA helicase
HQK30_00830	COG2856	Zn peptidase
HQK30_00840	COG1943	Transposase
HQK30_00860	COG0583	DNA-binding transcription factor activity
HQK30_00880	COG3161	chorismate lyase activity
HQK30_00915	COG1280	lysine exporter protein (LysE YggA)
HQK30_00925	COG2391	methyltransferase activity
HQK30_00935	COG1280	lysine exporter protein (LysE YggA)
HQK30_00945	COG2962	Rard protein
HQK30_00955	COG1012	belongs to the aldehyde dehydrogenase family
HQK30_00960	COG1396	sequence-specific DNA binding
HQK30_00975	COG0519	Catalyzes the synthesis of GMP from XMP
HQK30_00975	COG0518	GMP synthase (glutamine-hydrolyzing) activity
HQK30_00980	COG0686	Belongs to the AlaDH PNT family
HQK30_00985	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HQK30_01005	COG1322	Protein conserved in bacteria
HQK30_01010	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
HQK30_01015	COG0569	domain protein
HQK30_01020	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
HQK30_01020	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
HQK30_01025	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
HQK30_01030	COG0242	peptide deformylase activity
HQK30_01040	COG0758	DNA mediated transformation
HQK30_01045	COG2922	Belongs to the Smg family
HQK30_01050	COG0551	DNA topoisomerase type I activity
HQK30_01060	COG0009	L-threonylcarbamoyladenylate synthase
HQK30_01065	COG0408	coproporphyrinogen oxidase activity
HQK30_01070	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
HQK30_01080	COG0218	Necessary for normal cell division and for the maintenance of normal septation
HQK30_01090	COG3078	GTPase activator activity
HQK30_01100	COG0635	Involved in the biosynthesis of porphyrin-containing compound
HQK30_01105	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
HQK30_01110	COG2204	response regulator
HQK30_01115	COG3852	Histidine kinase
HQK30_01125	COG0174	glutamine synthetase
HQK30_01135	COG1295	ribonuclease BN
HQK30_01140	COG1295	ribonuclease BN
HQK30_01145	COG1490	D-aminoacyl-tRNA deacylase activity
HQK30_01155	COG0456	acetyltransferase
HQK30_01165	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
HQK30_01170	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HQK30_01175	COG2610	gluconate transmembrane transporter activity
HQK30_01180	COG3265	gluconokinase activity
HQK30_01190	COG0800	Aldolase
HQK30_01195	COG1609	Transcriptional regulator
HQK30_01205	COG4942	peptidase
HQK30_01210	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
HQK30_01215	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HQK30_01220	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
HQK30_01225	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
HQK30_01230	COG0316	Belongs to the HesB IscA family
HQK30_01230	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
HQK30_01240	COG0596	Alpha beta hydrolase
HQK30_01260	COG2183	response to ionizing radiation
HQK30_01265	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
HQK30_01270	COG0745	RESPONSE REGULATOR receiver
HQK30_01285	COG0051	transcription antitermination factor activity, RNA binding
HQK30_01290	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
HQK30_01295	COG0088	Forms part of the polypeptide exit tunnel
HQK30_01300	COG0089	rRNA binding
HQK30_01305	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
HQK30_01310	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
HQK30_01315	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
HQK30_01320	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
HQK30_01325	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
HQK30_01330	COG0255	Belongs to the universal ribosomal protein uL29 family
HQK30_01335	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
HQK30_01340	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
HQK30_01345	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
HQK30_01350	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
HQK30_01355	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
HQK30_01360	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
HQK30_01365	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
HQK30_01370	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
HQK30_01375	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
HQK30_01380	COG1841	ribosomal large subunit assembly
HQK30_01385	COG0200	Binds to the 23S rRNA
HQK30_01390	COG0201	protein transport
HQK30_01395	COG0257	Belongs to the bacterial ribosomal protein bL36 family
HQK30_01400	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
HQK30_01405	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
HQK30_01410	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
HQK30_01415	COG0202	RNA polymerase activity
HQK30_01420	COG0203	ribosomal protein L17
HQK30_01470	COG2249	NAD(P)H dehydrogenase (quinone) activity
HQK30_01475	COG0583	DNA-binding transcription factor activity
HQK30_01480	COG4221	oxidoreductase activity
HQK30_01495	COG1770	oligopeptidase
HQK30_01500	COG2358	TRAP transporter, solute receptor (TAXI family
HQK30_01515	COG3714	YhhN family
HQK30_01540	COG1301	dicarboxylic acid transport
HQK30_01550	COG2095	MarC family integral membrane protein
HQK30_01560	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
HQK30_01570	COG0741	lytic transglycosylase activity
HQK30_01580	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HQK30_01605	COG0742	ribosomal rna small subunit methyltransferase
HQK30_01610	COG0552	protein localization to endoplasmic reticulum
HQK30_01615	COG2884	Cell division ATP-binding protein ftsE
HQK30_01620	COG2177	Part of the ABC transporter FtsEX involved in
HQK30_01630	COG0288	reversible hydration of carbon dioxide
HQK30_01635	COG2188	Transcriptional regulator
HQK30_01640	COG1228	amidohydrolase
HQK30_01645	COG0010	Belongs to the arginase family
HQK30_01650	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
HQK30_01655	COG2986	histidine ammonia-lyase
HQK30_01660	COG0387	Pfam Sodium calcium exchanger
HQK30_01665	COG2200	EAL domain
HQK30_01670	COG2199	diguanylate cyclase activity
HQK30_01670	COG2200	EAL domain
HQK30_01715	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
HQK30_01720	COG1459	type II secretion system
HQK30_01735	COG4969	Belongs to the N-Me-Phe pilin family
HQK30_01740	COG4968	Prepilin-type N-terminal cleavage methylation domain
HQK30_01765	COG1077	Cell shape determining protein MreB Mrl
HQK30_01770	COG1792	Involved in formation and maintenance of cell shape
HQK30_01775	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
HQK30_01780	COG0424	maF-like protein
HQK30_01785	COG1530	ribonuclease E activity
HQK30_01790	COG3164	Protein of unknown function
HQK30_01805	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
HQK30_01810	COG0312	modulator of DNA gyrase
HQK30_01825	COG0477	Major facilitator Superfamily
HQK30_01835	COG3437	response regulator, receiver
HQK30_01840	COG0784	Response regulator, receiver
HQK30_01840	COG2205	protein histidine kinase activity
HQK30_01840	COG5002	protein histidine kinase activity
HQK30_01845	COG2172	sigma factor antagonist activity
HQK30_01850	COG1366	Belongs to the anti-sigma-factor antagonist family
HQK30_01870	COG3700	Belongs to the class B bacterial acid phosphatase family
HQK30_01875	COG2321	neutral zinc metallopeptidase
HQK30_01885	COG1639	'signal transduction protein
HQK30_01910	COG0189	ligase activity
HQK30_01915	COG0642	Histidine kinase
HQK30_01920	COG0745	RESPONSE REGULATOR receiver
HQK30_01945	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
HQK30_01950	COG0352	thiamine-phosphate diphosphorylase activity
HQK30_01955	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
HQK30_01965	COG2022	thiamine diphosphate biosynthetic process
HQK30_01970	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
HQK30_01975	COG1943	Transposase
HQK30_01990	COG3417	Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1B (PBP1b)
HQK30_02015	COG0814	amino acid
HQK30_02020	COG3932	Exopolysaccharide synthesis, ExoD
HQK30_02040	COG1733	regulation of RNA biosynthetic process
HQK30_02045	COG0456	acetyltransferase
HQK30_02080	COG1494	fructose-1,6-bisphosphatase
HQK30_02095	COG2959	enzyme of heme biosynthesis
HQK30_02105	COG0181	hydroxymethylbilane synthase activity
HQK30_02110	COG3072	Adenylate cyclase
HQK30_02115	COG0400	carboxylic ester hydrolase activity
HQK30_02120	COG1965	Belongs to the frataxin family
HQK30_02130	COG0019	diaminopimelate decarboxylase activity
HQK30_02135	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
HQK30_02150	COG1011	Hydrolase
HQK30_02170	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
HQK30_02175	COG0561	phosphatase activity
HQK30_02190	COG1129	ABC transporter
HQK30_02190	COG0842	Transport permease protein
HQK30_02200	COG1058	Belongs to the CinA family
HQK30_02200	COG1546	Belongs to the CinA family
HQK30_02205	COG1418	mRNA catabolic process
HQK30_02210	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
HQK30_02220	COG1522	sequence-specific DNA binding
HQK30_02225	COG1368	sulfuric ester hydrolase activity
HQK30_02245	COG1285	pathogenesis
HQK30_02265	COG4221	oxidoreductase activity
HQK30_02280	COG1979	alcohol dehydrogenase
HQK30_02290	COG2873	o-acetylhomoserine
HQK30_02300	COG4533	DNA binding
HQK30_02315	COG5380	lipid catabolic process
HQK30_02320	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
HQK30_02330	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
HQK30_02335	COG2949	membrane
HQK30_02340	COG3291	Pkd domain containing protein
HQK30_02350	COG3539	Fimbrial protein
HQK30_02360	COG3188	usher protein
HQK30_02365	COG3121	Chaperone
HQK30_02370	COG3539	Fimbrial protein
HQK30_02385	COG0318	PFAM AMP-dependent synthetase and ligase
HQK30_02390	COG1441	menaquinone biosynthetic process
HQK30_02395	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
HQK30_02400	COG0596	Alpha beta hydrolase
HQK30_02405	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
HQK30_02410	COG1169	isochorismate synthase
HQK30_02415	COG1575	Belongs to the MenA family. Type 1 subfamily
HQK30_02445	COG0513	Belongs to the DEAD box helicase family
HQK30_02450	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
HQK30_02455	COG1988	membrane-bound metal-dependent
HQK30_02470	COG1671	Belongs to the UPF0178 family
HQK30_02495	COG3263	regulation of cellular component size
HQK30_02500	COG3722	fumarate hydratase activity
HQK30_02505	COG0246	Mannitol dehydrogenase
HQK30_02510	COG2213	PTS system mannitol-specific
HQK30_02510	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
HQK30_02520	COG1309	transcriptional regulator
HQK30_02525	COG4776	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction
HQK30_02535	COG3916	Acyl-homoserine-lactone synthase
HQK30_02540	COG2771	luxR family
HQK30_02555	COG3133	Outer membrane lipoprotein
HQK30_02560	COG0456	acetyltransferase
HQK30_02585	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
HQK30_02595	COG3031	protein transport across the cell outer membrane
HQK30_02605	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
HQK30_02610	COG1459	type II secretion system
HQK30_02615	COG2165	general secretion pathway protein
HQK30_02625	COG2165	general secretion pathway protein
HQK30_02630	COG4795	General secretion pathway protein
HQK30_02635	COG3156	type II secretion system protein K
HQK30_02645	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
HQK30_02660	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
HQK30_02670	COG1902	pentaerythritol trinitrate reductase activity
HQK30_02675	COG1011	Hydrolase
HQK30_02680	COG0494	nUDIX hydrolase
HQK30_02685	COG1218	3'(2'),5'-bisphosphate nucleotidase
HQK30_02690	COG0814	amino acid
HQK30_02695	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HQK30_02700	COG2207	Transcriptional regulator
HQK30_02700	COG3708	Transcriptional regulator
HQK30_02710	COG0626	cystathionine gamma-synthase activity
HQK30_02715	COG0460	homoserine dehydrogenase
HQK30_02715	COG0527	aspartate kinase activity
HQK30_02725	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
HQK30_02735	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
HQK30_02740	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
HQK30_02750	COG0137	argininosuccinate synthase activity
HQK30_02755	COG0165	Argininosuccinate lyase
HQK30_02780	COG0110	maltose O-acetyltransferase activity
HQK30_02785	COG3174	membrane
HQK30_02790	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
HQK30_02800	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
HQK30_02805	COG4208	sulfate ABC transporter
HQK30_02810	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
HQK30_02815	COG0583	DNA-binding transcription factor activity
HQK30_02820	COG3397	chitin binding
HQK30_02855	COG4946	Tricorn protease homolog
HQK30_02855	COG0793	Belongs to the peptidase S41A family
HQK30_02875	COG1328	CTP reductase activity
HQK30_02880	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HQK30_02895	COG1448	Aminotransferase
HQK30_02935	COG0513	Belongs to the DEAD box helicase family
HQK30_02965	COG3112	Uncharacterised protein family (UPF0231)
HQK30_02970	COG3835	regulator
HQK30_02975	COG2610	gluconate transmembrane transporter activity
HQK30_02980	COG1929	Belongs to the glycerate kinase type-1 family
HQK30_03000	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
HQK30_03015	COG0347	Belongs to the P(II) protein family
HQK30_03020	COG1840	ABC-type Fe3 transport system, periplasmic component
HQK30_03030	COG3842	ATPase activity
HQK30_03035	COG2837	iron assimilation
HQK30_03040	COG1438	arginine binding
HQK30_03045	COG1126	abc transporter atp-binding protein
HQK30_03050	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HQK30_03055	COG4215	(ABC) transporter
HQK30_03060	COG4160	amino acid transport
HQK30_03065	COG0039	L-malate dehydrogenase activity
HQK30_03070	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
HQK30_03075	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
HQK30_03075	COG1017	nitric oxide dioxygenase activity
HQK30_03080	COG1959	2 iron, 2 sulfur cluster binding
HQK30_03085	COG4536	flavin adenine dinucleotide binding
HQK30_03090	COG4137	Cytochrome C assembly protein
HQK30_03095	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
HQK30_03100	COG0228	four-way junction DNA binding
HQK30_03105	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
HQK30_03110	COG0336	Belongs to the RNA methyltransferase TrmD family
HQK30_03115	COG0335	large ribosomal subunit rRNA binding
HQK30_03125	COG3066	DNA modification
HQK30_03130	COG1051	belongs to the nudix hydrolase family
HQK30_03140	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
HQK30_03145	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
HQK30_03150	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
HQK30_03160	COG0583	DNA-binding transcription factor activity
HQK30_03165	COG0640	Transcriptional regulator
HQK30_03170	COG0268	Binds directly to 16S ribosomal RNA
HQK30_03175	COG0728	peptidoglycan biosynthetic process
HQK30_03180	COG0196	riboflavin kinase activity
HQK30_03185	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
HQK30_03190	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
HQK30_03195	COG1047	Peptidyl-prolyl cis-trans
HQK30_03200	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
HQK30_03260	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
HQK30_03260	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
HQK30_03275	COG1854	S-ribosylhomocysteine lyase activity
HQK30_03280	COG3706	GGDEF domain
HQK30_03285	COG0557	exoribonuclease II activity
HQK30_03310	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HQK30_03320	COG2153	protein acetylation
HQK30_03325	COG0697	spore germination
HQK30_03345	COG2814	Major facilitator Superfamily
HQK30_03355	COG0583	DNA-binding transcription factor activity
HQK30_03365	COG1914	H( )-stimulated, divalent metal cation uptake system
HQK30_03370	COG0360	Binds together with S18 to 16S ribosomal RNA
HQK30_03375	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
HQK30_03380	COG0359	binds to the 23S rRNA
HQK30_03385	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
HQK30_03415	COG1238	metal cluster binding
HQK30_03420	COG0612	Peptidase, M16
HQK30_03425	COG2918	glutathione biosynthetic process
HQK30_03430	COG1022	Amp-dependent synthetase and ligase
HQK30_03440	COG0456	acetyltransferase
HQK30_03450	COG0714	Associated with various cellular activities
HQK30_03470	COG3300	MHYT domain
HQK30_03470	COG5001	Diguanylate cyclase
HQK30_03495	COG1902	pentaerythritol trinitrate reductase activity
HQK30_03505	COG2852	Protein conserved in bacteria
HQK30_03515	COG2957	Belongs to the agmatine deiminase family
HQK30_03520	COG0154	amidase activity
HQK30_03525	COG2801	Transposase and inactivated derivatives
HQK30_03545	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
HQK30_03550	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
HQK30_03560	COG0513	Belongs to the DEAD box helicase family
HQK30_03580	COG1912	Pfam S-adenosyl-l-methionine hydroxide adenosyltransferase
HQK30_03605	COG2070	2-Nitropropane dioxygenase
HQK30_03635	COG2816	NAD+ diphosphatase activity
HQK30_03640	COG2205	protein histidine kinase activity
HQK30_03645	COG0745	RESPONSE REGULATOR receiver
HQK30_03650	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HQK30_03655	COG0577	efflux transmembrane transporter activity
HQK30_03655	COG1136	(ABC) transporter
HQK30_03660	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HQK30_03665	COG1126	abc transporter atp-binding protein
HQK30_03670	COG0765	amino acid transport
HQK30_03675	COG0765	amino acid transport
HQK30_03680	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
HQK30_03685	COG1505	serine-type exopeptidase activity
HQK30_03690	COG2982	Protein involved in outer membrane biogenesis
HQK30_03700	COG1028	Short-chain dehydrogenase reductase Sdr
HQK30_03705	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
HQK30_03720	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
HQK30_03725	COG4991	sh3 domain protein
HQK30_03735	COG2816	NAD+ diphosphatase activity
HQK30_03740	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
HQK30_03745	COG1940	carbohydrate kinase activity
HQK30_03750	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
HQK30_03755	COG0126	phosphoglycerate kinase activity
HQK30_03765	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
HQK30_03810	COG0354	folic acid binding
HQK30_03815	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
HQK30_03825	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
HQK30_03830	COG1595	DNA-templated transcription, initiation
HQK30_03835	COG3073	An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E
HQK30_03850	COG0481	GTPase activity
HQK30_03855	COG0681	Belongs to the peptidase S26 family
HQK30_03860	COG0571	ribonuclease III activity
HQK30_03870	COG1381	Involved in DNA repair and RecF pathway recombination
HQK30_03875	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
HQK30_03885	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
HQK30_03890	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
HQK30_03895	COG3716	PTS system mannose fructose sorbose family IID component
HQK30_03905	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HQK30_03910	COG2222	sugar isomerase
HQK30_03920	COG1349	DNA-binding transcription factor activity
HQK30_03925	COG3023	N-Acetylmuramoyl-L-alanine amidase
HQK30_03930	COG4807	Protein conserved in bacteria
HQK30_03940	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HQK30_03945	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HQK30_03950	COG3956	TIGRFAM MazG family protein
HQK30_03955	COG0504	CTP synthase activity
HQK30_03960	COG0148	phosphopyruvate hydratase activity
HQK30_03965	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
HQK30_03970	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
HQK30_03980	COG0585	pseudouridine synthase activity
HQK30_03985	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
HQK30_03990	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
HQK30_03995	COG1238	metal cluster binding
HQK30_04010	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
HQK30_04015	COG0828	Belongs to the bacterial ribosomal protein bS21 family
HQK30_04020	COG1610	YqeY-like protein
HQK30_04025	COG0358	DNA primase activity
HQK30_04030	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HQK30_04115	COG0138	bifunctional purine biosynthesis protein purh
HQK30_04130	COG3036	rescue of stalled ribosome
HQK30_04135	COG0635	Involved in the biosynthesis of porphyrin-containing compound
HQK30_04140	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
HQK30_04150	COG0673	inositol 2-dehydrogenase activity
HQK30_04160	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HQK30_04165	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HQK30_04170	COG3227	Zinc metalloprotease (Elastase)
HQK30_04180	COG0477	Major facilitator Superfamily
HQK30_04190	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
HQK30_04195	COG1027	Aspartate ammonia-lyase
HQK30_04200	COG3030	protein affecting phage T7 exclusion by the F plasmid
HQK30_04205	COG0534	Mate efflux family protein
HQK30_04210	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
HQK30_04215	COG0459	protein refolding
HQK30_04225	COG3300	MHYT domain
HQK30_04225	COG5001	Diguanylate cyclase
HQK30_04235	COG0564	pseudouridine synthase activity
HQK30_04240	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
HQK30_04275	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HQK30_04285	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
HQK30_04295	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
HQK30_04305	COG4143	(ABC) transporter
HQK30_04340	COG0066	3-isopropylmalate dehydratase activity
HQK30_04345	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
HQK30_04350	COG0473	3-isopropylmalate dehydrogenase activity
HQK30_04355	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
HQK30_04365	COG0671	phosphoesterase, PA-phosphatase related
HQK30_04380	COG0028	Belongs to the TPP enzyme family
HQK30_04385	COG0440	acetolactate synthase activity
HQK30_04390	COG0280	phosphate acetyltransferase
HQK30_04390	COG0857	belongs to the CobB CobQ family
HQK30_04395	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HQK30_04405	COG3013	Belongs to the UPF0304 family
HQK30_04410	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
HQK30_04415	COG2716	regulation of RNA biosynthetic process
HQK30_04425	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
HQK30_04430	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
HQK30_04445	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
HQK30_04465	COG5002	protein histidine kinase activity
HQK30_04465	COG0784	Response regulator, receiver
HQK30_04465	COG2198	Histidine kinase
HQK30_04490	COG0840	transmembrane signaling receptor activity
HQK30_04500	COG1464	Belongs to the NlpA lipoprotein family
HQK30_04505	COG2011	ABC-type metal ion transport system permease component
HQK30_04510	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
HQK30_04530	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
HQK30_04530	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
HQK30_04535	COG0802	atpase or kinase
HQK30_04545	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
HQK30_04550	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
HQK30_04555	COG1923	regulation of RNA biosynthetic process
HQK30_04560	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
HQK30_04565	COG0330	HflC and HflK could
HQK30_04570	COG0330	HflC and HflK could
HQK30_04575	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
HQK30_04580	COG0142	geranyltranstransferase activity
HQK30_04585	COG0261	This protein binds to 23S rRNA in the presence of protein L20
HQK30_04590	COG0211	Belongs to the bacterial ribosomal protein bL27 family
HQK30_04595	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
HQK30_04605	COG0318	PFAM AMP-dependent synthetase and ligase
HQK30_04620	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
HQK30_04625	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HQK30_04635	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
HQK30_04640	COG2967	ApaG domain
HQK30_04645	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
HQK30_04650	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
HQK30_04660	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
HQK30_04665	COG3178	'Phosphotransferase
HQK30_04670	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
HQK30_04675	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
HQK30_04680	COG2252	PERMEase
HQK30_04690	COG0488	(ABC) transporter
HQK30_04705	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
HQK30_04710	COG0741	lytic transglycosylase activity
HQK30_04735	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
HQK30_04740	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HQK30_04750	COG3721	Heme iron utilization protein
HQK30_04755	COG0748	coenzyme F420 binding
HQK30_04775	COG4771	TonB-dependent receptor
HQK30_04780	COG2814	Major facilitator Superfamily
HQK30_04790	COG3655	Transcriptional regulator
HQK30_04800	COG2205	protein histidine kinase activity
HQK30_04800	COG2202	Pas domain
HQK30_04815	COG3397	chitin binding
HQK30_04830	COG1765	OsmC-like protein
HQK30_04845	COG3954	Phosphoribulokinase
HQK30_04850	COG2076	Multidrug Resistance protein
HQK30_04855	COG2076	Multidrug Resistance protein
HQK30_04860	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
HQK30_04865	COG0726	polysaccharide deacetylase
HQK30_04870	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
HQK30_04870	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
HQK30_04875	COG0463	Glycosyl transferase, family 2
HQK30_04880	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
HQK30_04890	COG3089	Belongs to the UPF0270 family
HQK30_04895	COG0429	hydrolase of the alpha beta-hydrolase fold
HQK30_04900	COG0835	chemotaxis
HQK30_04900	COG0784	Response regulator, receiver
HQK30_04910	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
HQK30_04915	COG1047	Peptidyl-prolyl cis-trans
HQK30_04920	COG2900	Belongs to the SlyX family
HQK30_04930	COG0545	Peptidyl-prolyl cis-trans isomerase
HQK30_04935	COG2204	response regulator
HQK30_04955	COG0737	Belongs to the 5'-nucleotidase family
HQK30_04960	COG2200	EAL domain
HQK30_04975	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HQK30_04980	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
HQK30_04990	COG2199	diguanylate cyclase activity
HQK30_04990	COG2200	EAL domain
HQK30_04990	COG2203	Gaf domain
HQK30_05015	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
HQK30_05020	COG2201	protein-glutamate methylesterase activity
HQK30_05025	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
HQK30_05035	COG0840	transmembrane signaling receptor activity
HQK30_05040	COG0835	chemotaxis
HQK30_05050	COG2198	Histidine kinase
HQK30_05050	COG0643	Histidine kinase
HQK30_05060	COG0745	RESPONSE REGULATOR receiver
HQK30_05080	COG1280	lysine exporter protein (LysE YggA)
HQK30_05085	COG0826	peptidase U32
HQK30_05115	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
HQK30_05140	COG0300	oxidoreductase activity
HQK30_05150	COG0840	transmembrane signaling receptor activity
HQK30_05160	COG2610	gluconate transmembrane transporter activity
HQK30_05165	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
HQK30_05170	COG3622	Belongs to the hyi family
HQK30_05175	COG0235	Class ii aldolase
HQK30_05185	COG2084	Dehydrogenase
HQK30_05190	COG1349	DNA-binding transcription factor activity
HQK30_05215	COG1605	Chorismate mutase
HQK30_05215	COG0077	Prephenate dehydratase
HQK30_05245	COG3272	Protein of unknown function (DUF1722)
HQK30_05250	COG0789	Transcriptional regulator
HQK30_05255	COG0415	Belongs to the DNA photolyase family
HQK30_05265	COG4221	oxidoreductase activity
HQK30_05280	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
HQK30_05305	COG0783	Belongs to the Dps family
HQK30_05310	COG1151	hydroxylamine reductase activity
HQK30_05320	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
HQK30_05325	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
HQK30_05325	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
HQK30_05340	COG2771	luxR family
HQK30_05355	COG3501	Rhs element vgr protein
HQK30_05420	COG0693	protein deglycase activity
HQK30_05425	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HQK30_05430	COG1666	GTP binding
HQK30_05435	COG3248	Nucleoside-binding outer membrane protein
HQK30_05440	COG2211	Major facilitator Superfamily
HQK30_05450	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
HQK30_05460	COG2813	Specifically methylates the guanine in position
HQK30_05465	COG0271	Belongs to the BolA IbaG family
HQK30_05470	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
HQK30_05475	COG1805	sodium ion transport
HQK30_05480	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
HQK30_05485	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
HQK30_05490	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
HQK30_05495	COG2871	sodium ion transport
HQK30_05500	COG1477	protein flavinylation
HQK30_05515	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HQK30_05520	COG0840	transmembrane signaling receptor activity
HQK30_05525	COG0583	DNA-binding transcription factor activity
HQK30_05535	COG2363	Small membrane protein
HQK30_05540	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
HQK30_05550	COG0473	3-isopropylmalate dehydrogenase activity
HQK30_05555	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HQK30_05560	COG1611	Belongs to the LOG family
HQK30_05565	COG3706	GGDEF domain
HQK30_05575	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
HQK30_05575	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
HQK30_05585	COG5595	Zn-ribbon-containing, possibly nucleic-acid-binding protein (DUF2310)
HQK30_05610	COG3098	single-species biofilm formation
HQK30_05615	COG0564	pseudouridine synthase activity
HQK30_05645	COG2171	N-acyltransferase activity
HQK30_05650	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
HQK30_05655	COG0024	Methionine aminopeptidase
HQK30_05660	COG0052	Belongs to the universal ribosomal protein uS2 family
HQK30_05665	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
HQK30_05670	COG0528	UMP kinase activity
HQK30_05675	COG0233	cytoplasmic translational termination
HQK30_05680	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
HQK30_05685	COG0575	Belongs to the CDS family
HQK30_05690	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
HQK30_05695	COG0750	zinc metalloprotease
HQK30_05710	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
HQK30_05715	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
HQK30_05720	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
HQK30_05725	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
HQK30_05730	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HQK30_05740	COG0825	malonyl-CoA metabolic process
HQK30_05745	COG3710	Transcriptional regulator
HQK30_05750	COG0531	amino acid
HQK30_05755	COG1982	Orn Lys Arg decarboxylase major
HQK30_05760	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
HQK30_05775	COG0814	amino acid
HQK30_05780	COG0531	amino acid
HQK30_05790	COG0488	(ABC) transporter
HQK30_05800	COG3590	peptidase
HQK30_05810	COG3706	GGDEF domain
HQK30_05845	COG0366	Alpha amylase catalytic
HQK30_05860	COG0463	Glycosyl transferase, family 2
HQK30_05875	COG2989	Protein conserved in bacteria
HQK30_05880	COG3108	Peptidase M15
HQK30_05890	COG2860	membrane
HQK30_05900	COG1196	nuclear chromosome segregation
HQK30_05905	COG3115	cell septum assembly
HQK30_05910	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
HQK30_05920	COG1328	CTP reductase activity
HQK30_05925	COG0602	queuosine metabolic process
HQK30_05955	COG1566	PFAM secretion protein HlyD family protein
HQK30_05960	COG1846	Transcriptional regulator
HQK30_05975	COG0281	malic enzyme
HQK30_05980	COG3290	protein histidine kinase activity
HQK30_05985	COG4565	transcriptional regulatory protein
HQK30_05990	COG0697	spore germination
HQK30_06000	COG1012	belongs to the aldehyde dehydrogenase family
HQK30_06005	COG3284	Transcriptional regulator
HQK30_06010	COG1960	acyl-CoA dehydrogenase activity
HQK30_06015	COG1804	L-carnitine dehydratase bile acid-inducible protein F
HQK30_06020	COG0346	lactoylglutathione lyase activity
HQK30_06025	COG0745	RESPONSE REGULATOR receiver
HQK30_06030	COG5002	protein histidine kinase activity
HQK30_06040	COG4783	chaperone-mediated protein folding
HQK30_06070	COG0545	Peptidyl-prolyl cis-trans isomerase
HQK30_06075	COG1131	(ABC) transporter
HQK30_06090	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HQK30_06095	COG4597	amino acid ABC transporter
HQK30_06100	COG0765	amino acid transport
HQK30_06105	COG1126	abc transporter atp-binding protein
HQK30_06115	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
HQK30_06125	COG0678	peroxiredoxin activity
HQK30_06135	COG0019	diaminopimelate decarboxylase activity
HQK30_06140	COG1115	amino acid carrier protein
HQK30_06145	COG0095	Lipoate-protein ligase
HQK30_06150	COG2233	PERMEase
HQK30_06165	COG0534	Mate efflux family protein
HQK30_06170	COG2207	Transcriptional regulator
HQK30_06175	COG0281	malic enzyme
HQK30_06205	COG0733	neurotransmitter:sodium symporter activity
HQK30_06210	COG1752	Esterase of the alpha-beta hydrolase superfamily
HQK30_06215	COG3706	GGDEF domain
HQK30_06220	COG1566	PFAM secretion protein HlyD family protein
HQK30_06225	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HQK30_06235	COG1032	radical SAM domain protein
HQK30_06245	COG1280	lysine exporter protein (LysE YggA)
HQK30_06250	COG1028	Short-chain dehydrogenase reductase Sdr
HQK30_06300	COG0673	inositol 2-dehydrogenase activity
HQK30_06305	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
HQK30_06310	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
HQK30_06315	COG0739	heme binding
HQK30_06315	COG0741	lytic transglycosylase activity
HQK30_06315	COG1196	nuclear chromosome segregation
HQK30_06320	COG0366	Alpha amylase catalytic
HQK30_06340	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HQK30_06350	COG0788	formyltetrahydrofolate deformylase activity
HQK30_06355	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
HQK30_06365	COG3118	belongs to the thioredoxin family
HQK30_06375	COG0791	NLP P60 protein
HQK30_06380	COG3129	Specifically methylates the adenine in position 1618 of 23S rRNA
HQK30_06395	COG1388	LysM domain
HQK30_06395	COG1376	ErfK ybiS ycfS ynhG family protein
HQK30_06420	COG4869	propanediol catabolic process
HQK30_06430	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HQK30_06435	COG1882	Formate acetyltransferase
HQK30_06440	COG1012	belongs to the aldehyde dehydrogenase family
HQK30_06440	COG1454	alcohol dehydrogenase
HQK30_06450	COG1012	belongs to the aldehyde dehydrogenase family
HQK30_06450	COG1454	alcohol dehydrogenase
HQK30_06485	COG0583	DNA-binding transcription factor activity
HQK30_06490	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
HQK30_06495	COG0243	molybdopterin cofactor binding
HQK30_06505	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
HQK30_06515	COG1960	acyl-CoA dehydrogenase activity
HQK30_06520	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HQK30_06530	COG0469	pyruvate kinase activity
HQK30_06535	COG1737	Transcriptional regulator
HQK30_06550	COG0745	RESPONSE REGULATOR receiver
HQK30_06555	COG2274	protein secretion by the type I secretion system
HQK30_06565	COG2274	protein secretion by the type I secretion system
HQK30_06575	COG2994	toxin metabolic process
HQK30_06580	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
HQK30_06580	COG1073	alpha beta
HQK30_06580	COG3064	Membrane
HQK30_06585	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
HQK30_06600	COG1342	Belongs to the UPF0251 family
HQK30_06605	COG0640	Transcriptional regulator
HQK30_06620	COG0798	PFAM Bile acid sodium symporter
HQK30_06640	COG1677	Flagellar hook-basal body complex protein FliE
HQK30_06650	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
HQK30_06705	COG1684	flagellar biosynthetic protein fliR
HQK30_06715	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
HQK30_06740	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
HQK30_06745	COG0643	Histidine kinase
HQK30_06745	COG2198	Histidine kinase
HQK30_06745	COG0784	Response regulator, receiver
HQK30_06750	COG2201	protein-glutamate methylesterase activity
HQK30_06755	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
HQK30_06765	COG1192	Involved in chromosome partitioning
HQK30_06775	COG0835	chemotaxis
HQK30_06790	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
HQK30_06795	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
HQK30_06800	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
HQK30_06805	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
HQK30_06810	COG1138	Cytochrome C-type biogenesis protein
HQK30_06815	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
HQK30_06820	COG4235	cytochrome complex assembly
HQK30_06820	COG3088	subunit of a heme lyase
HQK30_06840	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
HQK30_06845	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
HQK30_06845	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
HQK30_06860	COG0259	pyridoxamine-phosphate oxidase activity
HQK30_06865	COG0625	glutathione transferase activity
HQK30_06875	COG3153	acetyltransferase
HQK30_06890	COG2850	peptidyl-arginine hydroxylation
HQK30_06895	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
HQK30_06900	COG2915	High frequency lysogenization protein hflD homolog
HQK30_06905	COG0482	sulfurtransferase activity
HQK30_06915	COG1187	pseudouridine synthase activity
HQK30_06925	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
HQK30_06925	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HQK30_06925	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HQK30_06935	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
HQK30_06935	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HQK30_06935	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HQK30_06945	COG3081	Nucleoid-associated protein
HQK30_06950	COG0456	acetyltransferase
HQK30_06960	COG1609	Transcriptional regulator
HQK30_06965	COG1263	PTS System
HQK30_06965	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HQK30_06970	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
HQK30_06980	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HQK30_07000	COG2207	Transcriptional regulator
HQK30_07005	COG0538	isocitrate dehydrogenase activity
HQK30_07015	COG3048	D-serine ammonia-lyase activity
HQK30_07020	COG0583	DNA-binding transcription factor activity
HQK30_07025	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
HQK30_07040	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
HQK30_07045	COG2867	negative regulation of translational initiation
HQK30_07050	COG2914	Belongs to the UPF0125 (RnfH) family
HQK30_07055	COG0702	epimerase
HQK30_07060	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
HQK30_07065	COG1454	alcohol dehydrogenase
HQK30_07075	COG0564	pseudouridine synthase activity
HQK30_07105	COG1280	lysine exporter protein (LysE YggA)
HQK30_07125	COG3263	regulation of cellular component size
HQK30_07135	COG1876	peptidase activity
HQK30_07140	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
HQK30_07145	COG1393	Belongs to the ArsC family
HQK30_07150	COG0583	DNA-binding transcription factor activity
HQK30_07160	COG3069	C4-dicarboxylate transmembrane transporter activity
HQK30_07175	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
HQK30_07180	COG0017	Asparaginyl-tRNA synthetase
HQK30_07200	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
HQK30_07205	COG0156	8-amino-7-oxononanoate synthase activity
HQK30_07210	COG1073	alpha beta
HQK30_07210	COG2226	methyltransferase
HQK30_07215	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
HQK30_07220	COG0501	Belongs to the peptidase M48B family
HQK30_07230	COG3217	Mosc domain protein beta barrel domain protein
HQK30_07230	COG3217	Mosc domain protein beta barrel domain protein
HQK30_07230	COG0633	Ferredoxin
HQK30_07230	COG0633	Ferredoxin
HQK30_07240	COG1013	pyruvate-flavodoxin oxidoreductase activity
HQK30_07240	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
HQK30_07240	COG0674	pyruvate-flavodoxin oxidoreductase activity
HQK30_07240	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
HQK30_07245	COG2366	antibiotic biosynthetic process
HQK30_07250	COG1917	Cupin 2, conserved barrel domain protein
HQK30_07250	COG2169	Transcriptional regulator
HQK30_07255	COG2841	Protein conserved in bacteria
HQK30_07265	COG0534	Mate efflux family protein
HQK30_07305	COG1309	transcriptional regulator
HQK30_07320	COG0791	NLP P60 protein
HQK30_07330	COG0583	DNA-binding transcription factor activity
HQK30_07335	COG0450	alkyl hydroperoxide reductase
HQK30_07355	COG0500	methyltransferase
HQK30_07360	COG4106	trans-aconitate 2-methyltransferase activity
HQK30_07365	COG1801	Protein of unknown function DUF72
HQK30_07370	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
HQK30_07375	COG0217	transcriptional regulatory protein
HQK30_07380	COG2194	sulfuric ester hydrolase activity
HQK30_07385	COG1846	Transcriptional regulator
HQK30_07385	COG1940	carbohydrate kinase activity
HQK30_07390	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
HQK30_07395	COG0363	glucosamine-6-phosphate deaminase activity
HQK30_07400	COG1263	PTS System
HQK30_07400	COG2190	(PTS) system
HQK30_07400	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HQK30_07410	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
HQK30_07415	COG0735	belongs to the Fur family
HQK30_07425	COG0716	FMN binding
HQK30_07440	COG0596	Alpha beta hydrolase
HQK30_07445	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
HQK30_07450	COG0033	Phosphoglucomutase
HQK30_07460	COG1846	Transcriptional regulator
HQK30_07475	COG2951	lytic endotransglycosylase activity
HQK30_07480	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HQK30_07485	COG4136	ATPase activity
HQK30_07495	COG4134	Bacterial extracellular solute-binding protein
HQK30_07505	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
HQK30_07515	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HQK30_07520	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
HQK30_07530	COG0729	surface antigen
HQK30_07535	COG2911	Protein conserved in bacteria
HQK30_07555	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
HQK30_07565	COG0741	lytic transglycosylase activity
HQK30_07580	COG1607	acyl-coa hydrolase
HQK30_07590	COG3021	interspecies interaction between organisms
HQK30_07595	COG0741	lytic transglycosylase activity
HQK30_07595	COG1388	LysM domain
HQK30_07600	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
HQK30_07605	COG2226	methyltransferase
HQK30_07610	COG0328	RNA-DNA hybrid ribonuclease activity
HQK30_07615	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
HQK30_07625	COG0784	Response regulator, receiver
HQK30_07625	COG3437	response regulator, receiver
HQK30_07630	COG1960	acyl-CoA dehydrogenase activity
HQK30_07635	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
HQK30_07640	COG0121	glutamine amidotransferase
HQK30_07670	COG2197	response regulator
HQK30_07675	COG3850	Histidine kinase
HQK30_07680	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
HQK30_07685	COG1149	4fe-4S ferredoxin, iron-sulfur binding domain protein
HQK30_07685	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
HQK30_07695	COG0243	molybdopterin cofactor binding
HQK30_07700	COG0437	4 iron, 4 sulfur cluster binding
HQK30_07705	COG0348	domain, Protein
HQK30_07715	COG3005	denitrification pathway
HQK30_07720	COG0521	Mo-molybdopterin cofactor biosynthetic process
HQK30_07725	COG0315	cyclic pyranopterin monophosphate synthase activity
HQK30_07730	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
HQK30_07735	COG0314	molybdopterin synthase activity
HQK30_07750	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
HQK30_07755	COG2267	carboxylic ester hydrolase activity
HQK30_07760	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
HQK30_07770	COG0302	gtp cyclohydrolase
HQK30_07775	COG0840	transmembrane signaling receptor activity
HQK30_07780	COG2759	Belongs to the formate--tetrahydrofolate ligase family
HQK30_07790	COG0583	DNA-binding transcription factor activity
HQK30_07820	COG2195	Cleaves the N-terminal amino acid of tripeptides
HQK30_07830	COG1166	arginine decarboxylase activity
HQK30_07840	COG2015	COG2015, Alkyl sulfatase and related hydrolases
HQK30_07845	COG0583	DNA-binding transcription factor activity
HQK30_07865	COG0814	amino acid
HQK30_07875	COG3681	Belongs to the UPF0597 family
HQK30_07880	COG2964	Protein conserved in bacteria
HQK30_07890	COG1061	Type III restriction enzyme res subunit
HQK30_07900	COG0346	lactoylglutathione lyase activity
HQK30_07925	COG1187	pseudouridine synthase activity
HQK30_07935	COG2807	transmembrane transport
HQK30_07945	COG0583	DNA-binding transcription factor activity
HQK30_07950	COG2271	Major facilitator Superfamily
HQK30_07980	COG2979	Protein of unknown function (DUF533)
HQK30_07990	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HQK30_08000	COG1294	oxidase, subunit
HQK30_08020	COG3220	belongs to the UPF0276 family
HQK30_08035	COG2814	Major facilitator Superfamily
HQK30_08040	COG0656	L-ascorbic acid biosynthetic process
HQK30_08075	COG0583	DNA-binding transcription factor activity
HQK30_08085	COG0840	transmembrane signaling receptor activity
HQK30_08090	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
HQK30_08095	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
HQK30_08100	COG2271	Major facilitator Superfamily
HQK30_08105	COG1349	DNA-binding transcription factor activity
HQK30_08115	COG0584	glycerophosphoryl diester phosphodiesterase
HQK30_08120	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
HQK30_08125	COG0287	Prephenate dehydrogenase
HQK30_08125	COG1605	Chorismate mutase
HQK30_08130	COG0583	DNA-binding transcription factor activity
HQK30_08135	COG3085	chromosome segregation
HQK30_08140	COG4574	serine-type endopeptidase inhibitor activity
HQK30_08160	COG1770	oligopeptidase
HQK30_08165	COG4771	TonB-dependent receptor
HQK30_08170	COG3083	sulfuric ester hydrolase activity
HQK30_08175	COG3082	Protein of unknown function (DUF1414)
HQK30_08180	COG3081	Nucleoid-associated protein
HQK30_08190	COG1175	transmembrane transport
HQK30_08195	COG3833	ABC-type maltose transport systems, permease component
HQK30_08200	COG3842	ATPase activity
HQK30_08210	COG0596	Alpha beta hydrolase
HQK30_08225	COG0425	Belongs to the sulfur carrier protein TusA family
HQK30_08230	COG4783	chaperone-mediated protein folding
HQK30_08240	COG1393	Belongs to the ArsC family
HQK30_08255	COG3124	Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP
HQK30_08260	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
HQK30_08265	COG2431	L-lysine efflux transmembrane transporter activity
HQK30_08275	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HQK30_08310	COG1091	dTDP-4-dehydrorhamnose reductase activity
HQK30_08320	COG1210	Utp--glucose-1-phosphate uridylyltransferase
HQK30_08330	COG0438	transferase activity, transferring glycosyl groups
HQK30_08330	COG1216	Glycosyl transferase, family 2
HQK30_08350	COG1215	transferase activity, transferring glycosyl groups
HQK30_08395	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HQK30_08405	COG0446	pyridine nucleotide-disulphide oxidoreductase
HQK30_08410	COG2373	Large extracellular alpha-helical protein
HQK30_08415	COG4953	penicillin-binding protein 1C
HQK30_08425	COG0301	tRNA thio-modification
HQK30_08425	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HQK30_08445	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
HQK30_08475	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
HQK30_08485	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
HQK30_08505	COG0483	inositol monophosphate 1-phosphatase activity
HQK30_08515	COG0625	glutathione transferase activity
HQK30_08520	COG2814	Major facilitator Superfamily
HQK30_08540	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
HQK30_08545	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
HQK30_08550	COG0404	The glycine cleavage system catalyzes the degradation of glycine
HQK30_08555	COG0509	glycine decarboxylation via glycine cleavage system
HQK30_08560	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
HQK30_08560	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
HQK30_08565	COG0641	radical SAM
HQK30_08570	COG3119	arylsulfatase activity
HQK30_08585	COG3852	Histidine kinase
HQK30_08590	COG0477	Major facilitator Superfamily
HQK30_08595	COG3634	alkyl hydroperoxide reductase activity
HQK30_08605	COG0517	IMP dehydrogenase activity
HQK30_08610	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
HQK30_08615	COG0343	queuine tRNA-ribosyltransferase activity
HQK30_08620	COG1862	Preprotein translocase
HQK30_08625	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
HQK30_08630	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
HQK30_08645	COG0826	peptidase U32
HQK30_08650	COG0826	peptidase U32
HQK30_08655	COG3154	lipid carrier protein
HQK30_08675	COG1104	cysteine desulfurase activity
HQK30_08680	COG0822	iron-sulfur transferase activity
HQK30_08690	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
HQK30_08695	COG0443	Heat shock 70 kDa protein
HQK30_08700	COG0633	Ferredoxin
HQK30_08710	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
HQK30_08715	COG0105	UTP biosynthetic process
HQK30_08720	COG0820	rRNA (adenine-C2-)-methyltransferase activity
HQK30_08735	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
HQK30_08740	COG0124	histidyl-tRNA synthetase
HQK30_08745	COG2976	Protein conserved in bacteria
HQK30_08750	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
HQK30_08755	COG1160	GTP binding
HQK30_08760	COG1645	bacterial-type flagellum-dependent swarming motility
HQK30_08765	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
HQK30_08770	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HQK30_08770	COG0047	phosphoribosylformylglycinamidine synthase activity
HQK30_08775	COG2199	diguanylate cyclase activity
HQK30_08775	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
HQK30_08790	COG1007	ATP synthesis coupled electron transport
HQK30_08795	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
HQK30_08805	COG0713	ATP synthesis coupled electron transport
HQK30_08810	COG0839	Belongs to the complex I subunit 6 family
HQK30_08815	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
HQK30_08820	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
HQK30_08825	COG1034	ATP synthesis coupled electron transport
HQK30_08840	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
HQK30_08840	COG0649	NAD binding
HQK30_08845	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
HQK30_08850	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
HQK30_08855	COG1360	Flagellar Motor Protein
HQK30_08860	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
HQK30_08880	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
HQK30_08900	COG0724	RNA recognition motif
HQK30_08905	COG4989	oxidoreductase activity
HQK30_08930	COG3437	response regulator, receiver
HQK30_08935	COG0583	DNA-binding transcription factor activity
HQK30_08945	COG5001	Diguanylate cyclase
HQK30_08945	COG3300	MHYT domain
HQK30_08950	COG0778	Nitroreductase
HQK30_08970	COG0583	DNA-binding transcription factor activity
HQK30_08980	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
HQK30_08985	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
HQK30_08990	COG0539	negative regulation of cytoplasmic translation
HQK30_08995	COG0776	regulation of translation
HQK30_09005	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
HQK30_09025	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
HQK30_09030	COG0602	queuosine metabolic process
HQK30_09035	COG3530	Putative quorum-sensing-regulated virulence factor
HQK30_09040	COG2096	Adenosyltransferase
HQK30_09045	COG2916	Histone family protein nucleoid-structuring protein H-NS
HQK30_09050	COG1757	Na H antiporter
HQK30_09055	COG1435	thymidine kinase activity
HQK30_09085	COG3501	Rhs element vgr protein
HQK30_09115	COG3501	Rhs element vgr protein
HQK30_09220	COG3501	Rhs element vgr protein
HQK30_09265	COG2801	Transposase and inactivated derivatives
HQK30_09290	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
HQK30_09295	COG1278	Cold shock
HQK30_09300	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
HQK30_09305	COG0542	response to heat
HQK30_09310	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
HQK30_09315	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
HQK30_09320	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
HQK30_09325	COG3134	Outer membrane lipoprotein
HQK30_09330	COG3706	GGDEF domain
HQK30_09335	COG0492	ferredoxin-NADP+ reductase activity
HQK30_09345	COG0531	amino acid
HQK30_09345	COG1674	ftsk spoiiie
HQK30_09350	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
HQK30_09355	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
HQK30_09360	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
HQK30_09365	COG1286	toxin biosynthetic process
HQK30_09370	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
HQK30_09380	COG4172	Belongs to the ABC transporter superfamily
HQK30_09390	COG4171	peptide transport system, permease
HQK30_09395	COG4168	peptide transport system, permease
HQK30_09405	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
HQK30_09410	COG1842	Phage shock protein A
HQK30_09425	COG3106	COG3106 Predicted ATPase
HQK30_09430	COG3768	UPF0283 membrane protein
HQK30_09440	COG2154	pterin-4-alpha-carbinolamine dehydratase
HQK30_09465	COG2885	chlorophyll binding
HQK30_09470	COG0861	Integral membrane protein TerC family
HQK30_09485	COG1022	Amp-dependent synthetase and ligase
HQK30_09490	COG0295	cytidine deaminase activity
HQK30_09495	COG1346	cytolysis
HQK30_09500	COG1380	Effector of murein hydrolase LrgA
HQK30_09505	COG3345	alpha-galactosidase
HQK30_09515	COG2925	Exonuclease
HQK30_09520	COG0583	DNA-binding transcription factor activity
HQK30_09530	COG0257	Belongs to the bacterial ribosomal protein bL36 family
HQK30_09535	COG0254	rRNA binding
HQK30_09550	COG1451	nucleotide metabolic process
HQK30_09565	COG3069	C4-dicarboxylate transmembrane transporter activity
HQK30_09575	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
HQK30_09575	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
HQK30_09580	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
HQK30_09605	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
HQK30_09620	COG0567	Dehydrogenase, E1 component
HQK30_09625	COG0508	dehydrogenase complex catalyzes the overall conversion of
HQK30_09630	COG0045	succinate-CoA ligase (ADP-forming) activity
HQK30_09635	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
HQK30_09645	COG0300	oxidoreductase activity
HQK30_09655	COG1280	lysine exporter protein (LysE YggA)
HQK30_09660	COG2983	Belongs to the UPF0260 family
HQK30_09665	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
HQK30_09675	COG3842	ATPase activity
HQK30_09680	COG1840	ABC-type Fe3 transport system, periplasmic component
HQK30_09690	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
HQK30_09700	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
HQK30_09705	COG1882	Formate acetyltransferase
HQK30_09710	COG2116	formate transmembrane transporter activity
HQK30_09715	COG1944	ATP diphosphatase activity
HQK30_09725	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
HQK30_09730	COG0612	Peptidase, M16
HQK30_09745	COG2910	NAD(P)H-binding
HQK30_09750	COG0583	DNA-binding transcription factor activity
HQK30_09765	COG4774	siderophore transport
HQK30_09780	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
HQK30_09795	COG0517	IMP dehydrogenase activity
HQK30_09795	COG0516	GMP reductase activity
HQK30_09800	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
HQK30_09805	COG3046	protein related to deoxyribodipyrimidine photolyase
HQK30_09815	COG3033	Beta-eliminating lyase
HQK30_09830	COG3088	subunit of a heme lyase
HQK30_09830	COG4235	cytochrome complex assembly
HQK30_09835	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
HQK30_09840	COG1138	Cytochrome C-type biogenesis protein
HQK30_09845	COG3301	Polysulphide reductase, NrfD
HQK30_09850	COG0437	4 iron, 4 sulfur cluster binding
HQK30_09855	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
HQK30_09870	COG0247	lactate metabolic process
HQK30_09875	COG3075	Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses fumarate or nitrate as electron acceptor
HQK30_09880	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
HQK30_09885	COG3012	SEC-C Motif Domain Protein
HQK30_09890	COG0840	transmembrane signaling receptor activity
HQK30_09895	COG1846	Transcriptional regulator
HQK30_09895	COG1940	carbohydrate kinase activity
HQK30_09900	COG3290	protein histidine kinase activity
HQK30_09905	COG4565	transcriptional regulatory protein
HQK30_09925	COG0739	heme binding
HQK30_09925	COG1196	nuclear chromosome segregation
HQK30_09925	COG0741	lytic transglycosylase activity
HQK30_09930	COG0569	domain protein
HQK30_09930	COG2985	domain, Protein
HQK30_09945	COG0556	nucleotide-excision repair
HQK30_09955	COG0586	Pfam SNARE associated Golgi protein
HQK30_09960	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
HQK30_09965	COG3067	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
HQK30_09970	COG2186	Transcriptional regulator
HQK30_09975	COG2719	SpoVR family
HQK30_09980	COG2718	Belongs to the UPF0229 family
HQK30_09985	COG2766	serine protein kinase
HQK30_09990	COG0514	ATP-dependent DNA helicase (RecQ)
HQK30_09995	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
HQK30_10000	COG0814	amino acid
HQK30_10030	COG0058	SHG alpha-glucan phosphorylase activity
HQK30_10040	COG0471	metal ion transport
HQK30_10045	COG3118	belongs to the thioredoxin family
HQK30_10055	COG1132	(ABC) transporter
HQK30_10060	COG1132	(ABC) transporter
HQK30_10075	COG2501	S4 domain
HQK30_10105	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
HQK30_10110	COG2329	Antibiotic biosynthesis monooxygenase
HQK30_10150	COG0513	Belongs to the DEAD box helicase family
HQK30_10155	COG0386	Belongs to the glutathione peroxidase family
HQK30_10165	COG1181	Belongs to the D-alanine--D-alanine ligase family
HQK30_10180	COG0730	response to heat
HQK30_10185	COG0583	DNA-binding transcription factor activity
HQK30_10200	COG3593	DNA synthesis involved in DNA repair
HQK30_10245	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
HQK30_10250	COG1011	Hydrolase
HQK30_10255	COG1473	amidohydrolase
HQK30_10260	COG0205	6-phosphofructokinase activity
HQK30_10270	COG1434	Gram-negative-bacterium-type cell wall biogenesis
HQK30_10275	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
HQK30_10285	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
HQK30_10290	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
HQK30_10295	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
HQK30_10320	COG0242	peptide deformylase activity
HQK30_10345	COG0384	phenazine biosynthesis protein PhzF
HQK30_10350	COG2824	Alkylphosphonate utilization operon protein PhnA
HQK30_10370	COG0588	phosphoglycerate mutase activity
HQK30_10375	COG3706	GGDEF domain
HQK30_10385	COG2840	Smr protein MutS2
HQK30_10390	COG2890	protein-(glutamine-N5) methyltransferase activity
HQK30_10395	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
HQK30_10405	COG0513	Belongs to the DEAD box helicase family
HQK30_10420	COG0814	amino acid
HQK30_10425	COG1609	Transcriptional regulator
HQK30_10430	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
HQK30_10430	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
HQK30_10435	COG1105	Belongs to the carbohydrate kinase PfkB family
HQK30_10440	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
HQK30_10440	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HQK30_10440	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HQK30_10445	COG3313	Fe-S protein
HQK30_10450	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
HQK30_10455	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
HQK30_10465	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HQK30_10475	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
HQK30_10500	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
HQK30_10505	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
HQK30_10510	COG0291	Belongs to the bacterial ribosomal protein bL35 family
HQK30_10515	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
HQK30_10520	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
HQK30_10525	COG0072	phenylalanine-tRNA ligase activity
HQK30_10525	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HQK30_10530	COG0776	regulation of translation
HQK30_10535	COG0784	Response regulator, receiver
HQK30_10535	COG2205	protein histidine kinase activity
HQK30_10560	COG2199	diguanylate cyclase activity
HQK30_10565	COG1609	Transcriptional regulator
HQK30_10570	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HQK30_10575	COG1879	ABC-type sugar transport system periplasmic component
HQK30_10580	COG1172	Belongs to the binding-protein-dependent transport system permease family
HQK30_10585	COG1129	ABC transporter
HQK30_10590	COG1869	D-ribose catabolic process
HQK30_10610	COG0037	tRNA processing
HQK30_10615	COG0589	response to stress
HQK30_10620	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
HQK30_10645	COG2010	Cytochrome c
HQK30_10660	COG3278	Belongs to the heme-copper respiratory oxidase family
HQK30_10670	COG1956	GAF domain-containing protein
HQK30_10675	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
HQK30_10685	COG0308	aminopeptidase N
HQK30_10695	COG2902	Dehydrogenase
HQK30_10700	COG0167	dihydroorotate dehydrogenase activity
HQK30_10715	COG0116	Belongs to the methyltransferase superfamily
HQK30_10715	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
HQK30_10740	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
HQK30_10745	COG1067	ATP-dependent peptidase activity
HQK30_10785	COG4128	Pfam Zonular occludens toxin
HQK30_10810	COG3141	response to X-ray
HQK30_10820	COG4221	oxidoreductase activity
HQK30_10865	COG0372	Belongs to the citrate synthase family
HQK30_10870	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
HQK30_10880	COG2995	paraquat-inducible protein a
HQK30_10885	COG3008	intermembrane lipid transfer
HQK30_10890	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
HQK30_10890	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
HQK30_10905	COG0084	hydrolase, TatD family'
HQK30_10910	COG0470	DNA polymerase III
HQK30_10915	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
HQK30_10920	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
HQK30_10925	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
HQK30_10935	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
HQK30_10940	COG1028	Short-chain dehydrogenase reductase Sdr
HQK30_10950	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HQK30_10955	COG0416	fatty acid biosynthetic process
HQK30_10960	COG0333	Belongs to the bacterial ribosomal protein bL32 family
HQK30_10965	COG1399	metal-binding, possibly nucleic acid-binding protein
HQK30_10975	COG0424	maF-like protein
HQK30_10980	COG0546	phosphoglycolate phosphatase activity
HQK30_10985	COG0564	pseudouridine synthase activity
HQK30_10990	COG1530	ribonuclease E activity
HQK30_10995	COG0306	phosphate transporter
HQK30_11000	COG0717	Belongs to the dCTP deaminase family
HQK30_11005	COG0572	uridine kinase
HQK30_11010	COG0489	protein tyrosine kinase activity
HQK30_11015	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HQK30_11015	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HQK30_11020	COG0625	glutathione transferase activity
HQK30_11025	COG1254	Belongs to the acylphosphatase family
HQK30_11030	COG0840	transmembrane signaling receptor activity
HQK30_11040	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
HQK30_11055	COG0709	Synthesizes selenophosphate from selenide and ATP
HQK30_11060	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
HQK30_11065	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
HQK30_11070	COG3437	response regulator, receiver
HQK30_11080	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
HQK30_11090	COG1643	Atp-dependent helicase
HQK30_11095	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
HQK30_11095	COG0517	IMP dehydrogenase activity
HQK30_11095	COG0617	tRNA 3'-terminal CCA addition
HQK30_11115	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
HQK30_11120	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
HQK30_11130	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
HQK30_11135	COG2832	Protein of unknown function (DUF454)
HQK30_11140	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HQK30_11155	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
HQK30_11160	COG0318	PFAM AMP-dependent synthetase and ligase
HQK30_11165	COG2267	carboxylic ester hydrolase activity
HQK30_11175	COG1214	PFAM Peptidase M22, glycoprotease
HQK30_11180	COG1199	ATP-dependent helicase activity
HQK30_11190	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
HQK30_11195	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
HQK30_11200	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
HQK30_11205	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
HQK30_11205	COG0131	Imidazoleglycerol-phosphate dehydratase
HQK30_11210	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
HQK30_11215	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
HQK30_11220	COG3437	response regulator, receiver
HQK30_11230	COG2205	protein histidine kinase activity
HQK30_11230	COG2198	Histidine kinase
HQK30_11230	COG0784	Response regulator, receiver
HQK30_11235	COG0107	imidazoleglycerol-phosphate synthase activity
HQK30_11240	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
HQK30_11240	COG0140	phosphoribosyl-ATP diphosphatase activity
HQK30_11250	COG2378	regulation of single-species biofilm formation
HQK30_11260	COG1288	antiporter activity
HQK30_11270	COG3134	Outer membrane lipoprotein
HQK30_11280	COG2080	2 iron, 2 sulfur cluster binding
HQK30_11285	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
HQK30_11290	COG1529	Aldehyde oxidase and xanthine dehydrogenase
HQK30_11295	COG2252	PERMEase
HQK30_11300	COG0402	S-adenosylhomocysteine deaminase activity
HQK30_11305	COG2233	PERMEase
HQK30_11310	COG2080	2 iron, 2 sulfur cluster binding
HQK30_11310	COG1529	Aldehyde oxidase and xanthine dehydrogenase
HQK30_11315	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
HQK30_11320	COG0402	S-adenosylhomocysteine deaminase activity
HQK30_11325	COG0493	'glutamate synthase
HQK30_11325	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
HQK30_11330	COG2068	MobA-Related Protein
HQK30_11335	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
HQK30_11340	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
HQK30_11340	COG3608	succinylglutamate desuccinylase aspartoacylase
HQK30_11345	COG0697	spore germination
HQK30_11350	COG0549	Belongs to the carbamate kinase family
HQK30_11360	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
HQK30_11365	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
HQK30_11370	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
HQK30_11395	COG1250	3-hydroxyacyl-CoA dehydrogenase
HQK30_11395	COG1024	Enoyl-CoA hydratase
HQK30_11400	COG0183	Belongs to the thiolase family
HQK30_11405	COG0714	Associated with various cellular activities
HQK30_11435	COG1595	DNA-templated transcription, initiation
HQK30_11450	COG2067	long-chain fatty acid transport protein
HQK30_11455	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
HQK30_11475	COG3123	guanosine phosphorylase activity
HQK30_11480	COG1760	l-serine dehydratase
HQK30_11485	COG1760	l-serine dehydratase
HQK30_11490	COG2951	lytic endotransglycosylase activity
HQK30_11495	COG3100	YcgL domain-containing protein
HQK30_11500	COG0850	regulation of cytokinetic process
HQK30_11505	COG2894	cell division
HQK30_11510	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
HQK30_11515	COG3099	Belongs to the UPF0263 family
HQK30_11520	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
HQK30_11560	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
HQK30_11565	COG0697	spore germination
HQK30_11570	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
HQK30_11575	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
HQK30_11585	COG0307	riboflavin synthase, alpha
HQK30_11595	COG0534	Mate efflux family protein
HQK30_11625	COG0417	DNA replication proofreading
HQK30_11635	COG3300	MHYT domain
HQK30_11635	COG5001	Diguanylate cyclase
HQK30_11650	COG1560	Kdo2-lipid A biosynthetic process
HQK30_11655	COG1560	Kdo2-lipid A biosynthetic process
HQK30_11665	COG0583	DNA-binding transcription factor activity
HQK30_11670	COG0673	inositol 2-dehydrogenase activity
HQK30_11675	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
HQK30_11680	COG0583	DNA-binding transcription factor activity
HQK30_11690	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
HQK30_11695	COG2723	6-phospho-beta-galactosidase activity
HQK30_11700	COG0583	DNA-binding transcription factor activity
HQK30_11705	COG0438	transferase activity, transferring glycosyl groups
HQK30_11770	COG0438	transferase activity, transferring glycosyl groups
HQK30_11775	COG1215	transferase activity, transferring glycosyl groups
HQK30_11780	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
HQK30_11830	COG0667	Aldo Keto reductase
HQK30_11835	COG0583	DNA-binding transcription factor activity
HQK30_11840	COG0702	epimerase
HQK30_11845	COG1506	peptidase
HQK30_11845	COG0823	Involved in the tonB-independent uptake of proteins
HQK30_11850	COG1073	alpha beta
HQK30_11865	COG0730	response to heat
HQK30_11875	COG1028	Short-chain dehydrogenase reductase Sdr
HQK30_11885	COG1024	Enoyl-CoA hydratase
HQK30_11890	COG1024	Enoyl-CoA hydratase
HQK30_11895	COG1960	acyl-CoA dehydrogenase activity
HQK30_11905	COG1960	acyl-CoA dehydrogenase activity
HQK30_11910	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
HQK30_11945	COG1584	GPR1 FUN34 yaaH family protein
HQK30_11960	COG1115	amino acid carrier protein
HQK30_11990	COG1024	Enoyl-CoA hydratase
HQK30_12005	COG3162	membrane
HQK30_12010	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HQK30_12015	COG0488	(ABC) transporter
HQK30_12020	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
HQK30_12025	COG0776	regulation of translation
HQK30_12030	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
HQK30_12035	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
HQK30_12040	COG0740	serine-type endopeptidase activity
HQK30_12045	COG0544	peptidyl-prolyl cis-trans isomerase activity
HQK30_12055	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
HQK30_12060	COG4591	ABC-type transport system involved in lipoprotein release permease component
HQK30_12065	COG1136	(ABC) transporter
HQK30_12070	COG4591	ABC-type transport system involved in lipoprotein release permease component
HQK30_12080	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
HQK30_12085	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
HQK30_12090	COG4166	transmembrane transport
HQK30_12095	COG0697	spore germination
HQK30_12105	COG2062	phosphohistidine phosphatase, SixA
HQK30_12150	COG0519	Catalyzes the synthesis of GMP from XMP
HQK30_12150	COG0518	GMP synthase (glutamine-hydrolyzing) activity
HQK30_12155	COG0517	IMP dehydrogenase activity
HQK30_12155	COG0516	GMP reductase activity
HQK30_12160	COG3158	transport of potassium into the cell
HQK30_12180	COG0697	spore germination
HQK30_12185	COG1570	exodeoxyribonuclease VII activity
HQK30_12200	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
HQK30_12205	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
HQK30_12210	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
HQK30_12250	COG4771	TonB-dependent receptor
HQK30_12255	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HQK30_12260	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HQK30_12265	COG1120	ATPase activity
HQK30_12275	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
HQK30_12280	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HQK30_12290	COG1028	Short-chain dehydrogenase reductase Sdr
HQK30_12295	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HQK30_12300	COG3433	isochorismatase activity
HQK30_12300	COG1535	isochorismatase
HQK30_12305	COG1021	2,3-dihydroxybenzoate-AMP ligase
HQK30_12325	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
HQK30_12330	COG5001	Diguanylate cyclase
HQK30_12330	COG3300	MHYT domain
HQK30_12345	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HQK30_12350	COG3788	relative of glutathione S-transferase, MAPEG superfamily
HQK30_12355	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
HQK30_12360	COG0563	adenylate kinase activity
HQK30_12365	COG0326	Molecular chaperone. Has ATPase activity
HQK30_12370	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
HQK30_12395	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
HQK30_12405	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
HQK30_12410	COG3158	transport of potassium into the cell
HQK30_12420	COG2223	nitrite transmembrane transporter activity
HQK30_12425	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
HQK30_12435	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
HQK30_12440	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
HQK30_12445	COG0651	ATP synthesis coupled electron transport
HQK30_12450	COG0650	Formate hydrogenlyase subunit 4
HQK30_12455	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
HQK30_12455	COG3261	NADH dehydrogenase
HQK30_12460	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
HQK30_12465	COG3260	NADH ubiquinone oxidoreductase 20
HQK30_12475	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
HQK30_12485	COG1921	L-seryl-tRNASec selenium transferase activity
HQK30_12495	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
HQK30_12500	COG0298	carbon dioxide binding
HQK30_12510	COG0309	Hydrogenase expression formation protein (HypE)
HQK30_12515	COG0375	protein maturation
HQK30_12520	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
HQK30_12525	COG3842	ATPase activity
HQK30_12535	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
HQK30_12540	COG0601	transmembrane transport
HQK30_12550	COG1773	rubredoxin
HQK30_12555	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
HQK30_12560	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
HQK30_12565	COG5557	Pfam Polysulphide reductase, NrfD
HQK30_12570	COG0437	4 iron, 4 sulfur cluster binding
HQK30_12575	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
HQK30_12580	COG0745	RESPONSE REGULATOR receiver
HQK30_12590	COG0643	Histidine kinase
HQK30_12590	COG2198	Histidine kinase
HQK30_12595	COG0840	transmembrane signaling receptor activity
HQK30_12595	COG3290	protein histidine kinase activity
HQK30_12600	COG0835	chemotaxis
HQK30_12610	COG2201	protein-glutamate methylesterase activity
HQK30_12620	COG0840	transmembrane signaling receptor activity
HQK30_12625	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HQK30_12640	COG0659	secondary active sulfate transmembrane transporter activity
HQK30_12670	COG0672	)-iron permease
HQK30_12690	COG2814	Major facilitator Superfamily
HQK30_12710	COG1136	(ABC) transporter
HQK30_12750	COG1139	Iron-sulfur cluster binding protein
HQK30_12755	COG0247	lactate metabolic process
HQK30_12760	COG1620	l-lactate permease
HQK30_12765	COG0583	DNA-binding transcription factor activity
HQK30_12770	COG0596	Alpha beta hydrolase
HQK30_12790	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HQK30_12795	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
HQK30_12795	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
HQK30_12800	COG0527	aspartate kinase activity
HQK30_12810	COG1368	sulfuric ester hydrolase activity
HQK30_12815	COG1619	proteins homologs of microcin C7 resistance protein MccF
HQK30_12825	COG0393	Putative heavy-metal-binding
HQK30_12845	COG1252	NADH dehydrogenase
HQK30_12850	COG3150	esterase
HQK30_12855	COG2233	PERMEase
HQK30_12870	COG2354	Protein conserved in bacteria
HQK30_12890	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
HQK30_12895	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
HQK30_12930	COG0537	adenosine 5'-monophosphoramidase activity
HQK30_12945	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
HQK30_12960	COG1301	dicarboxylic acid transport
HQK30_12970	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HQK30_12975	COG0861	Integral membrane protein TerC family
HQK30_12985	COG0444	Belongs to the ABC transporter superfamily
HQK30_12990	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
HQK30_12995	COG0601	transmembrane transport
HQK30_13005	COG2095	MarC family integral membrane protein
HQK30_13015	COG1012	belongs to the aldehyde dehydrogenase family
HQK30_13015	COG1454	alcohol dehydrogenase
HQK30_13020	COG2199	diguanylate cyclase activity
HQK30_13020	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
HQK30_13025	COG3275	phosphorelay sensor kinase activity
HQK30_13030	COG3279	Response regulator of the LytR AlgR family
HQK30_13035	COG1966	Carbon starvation protein
HQK30_13045	COG1566	PFAM secretion protein HlyD family protein
HQK30_13050	COG1061	Type III restriction enzyme res subunit
HQK30_13055	COG2027	D-alanyl-D-alanine carboxypeptidase
HQK30_13060	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
HQK30_13070	COG0436	Aminotransferase
HQK30_13075	COG3264	Mechanosensitive ion channel
HQK30_13075	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
HQK30_13080	COG1288	antiporter activity
HQK30_13085	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
HQK30_13095	COG0697	spore germination
HQK30_13100	COG4657	Part of a membrane complex involved in electron transport
HQK30_13105	COG2878	Part of a membrane complex involved in electron transport
HQK30_13115	COG4658	electron transport chain
HQK30_13120	COG4659	FMN binding
HQK30_13125	COG4660	Part of a membrane complex involved in electron transport
HQK30_13130	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
HQK30_13135	COG0346	lactoylglutathione lyase activity
HQK30_13150	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
HQK30_13155	COG2056	Na+-H+ antiporter family
HQK30_13165	COG2050	protein possibly involved in aromatic compounds catabolism
HQK30_13175	COG0247	lactate metabolic process
HQK30_13175	COG0277	FAD linked oxidase domain protein
HQK30_13185	COG1253	flavin adenine dinucleotide binding
HQK30_13190	COG1902	pentaerythritol trinitrate reductase activity
HQK30_13195	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
HQK30_13200	COG0647	UMP catabolic process
HQK30_13205	COG4651	solute:proton antiporter activity
HQK30_13205	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
HQK30_13215	COG0367	asparagine synthase
HQK30_13225	COG0625	glutathione transferase activity
HQK30_13235	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
HQK30_13250	COG0564	pseudouridine synthase activity
HQK30_13255	COG5001	Diguanylate cyclase
HQK30_13260	COG0840	transmembrane signaling receptor activity
HQK30_13270	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
HQK30_13270	COG0392	lysyltransferase activity
HQK30_13275	COG2194	sulfuric ester hydrolase activity
HQK30_13295	COG0670	Belongs to the BI1 family
HQK30_13300	COG1289	transmembrane transporter activity
HQK30_13305	COG2920	part of a sulfur-relay system
HQK30_13310	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
HQK30_13315	COG0285	dihydrofolate synthase activity
HQK30_13320	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
HQK30_13325	COG0101	tRNA pseudouridine synthase activity
HQK30_13335	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
HQK30_13340	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
HQK30_13345	COG0671	phosphoesterase, PA-phosphatase related
HQK30_13350	COG1464	Belongs to the NlpA lipoprotein family
HQK30_13390	COG0574	Belongs to the PEP-utilizing enzyme family
HQK30_13390	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HQK30_13395	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
HQK30_13465	COG1242	4 iron, 4 sulfur cluster binding
HQK30_13470	COG0070	glutamate synthase
HQK30_13470	COG0069	glutamate synthase activity
HQK30_13470	COG0067	glutamate synthase
HQK30_13475	COG0493	'glutamate synthase
HQK30_13490	COG0789	Transcriptional regulator
HQK30_13505	COG4104	PAAR repeat-containing protein
HQK30_13515	COG0513	Belongs to the DEAD box helicase family
HQK30_13520	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HQK30_13565	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
HQK30_13570	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
HQK30_13575	COG0505	Belongs to the CarA family
HQK30_13580	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
HQK30_13590	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
HQK30_13595	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
HQK30_13600	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
HQK30_13605	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
HQK30_13610	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
HQK30_13615	COG4138	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system
HQK30_13625	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HQK30_13625	COG2205	protein histidine kinase activity
HQK30_13665	COG0023	Translation Initiation Factor
HQK30_13670	COG2119	membrane
HQK30_13700	COG2203	Gaf domain
HQK30_13700	COG2199	diguanylate cyclase activity
HQK30_13715	COG1204	response to ionizing radiation
HQK30_13725	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
HQK30_13735	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
HQK30_13740	COG3301	Polysulphide reductase, NrfD
HQK30_13745	COG0437	4 iron, 4 sulfur cluster binding
HQK30_13750	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
HQK30_13800	COG0322	excinuclease ABC activity
HQK30_13805	COG2197	response regulator
HQK30_13810	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
HQK30_13815	COG2835	tetraacyldisaccharide 4'-kinase activity
HQK30_13820	COG1663	tetraacyldisaccharide 4'-kinase activity
HQK30_13830	COG0658	competence protein
HQK30_13830	COG2333	competence protein COMEC
HQK30_13845	COG0433	COG0433 Predicted ATPase
HQK30_13850	COG1448	Aminotransferase
HQK30_13865	COG1199	ATP-dependent helicase activity
HQK30_13875	COG0123	including yeast histone deacetylase and acetoin utilization protein
HQK30_13880	COG0477	Major facilitator Superfamily
HQK30_13885	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
HQK30_13910	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
HQK30_13925	COG2271	Major facilitator Superfamily
HQK30_13930	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HQK30_13935	COG0765	amino acid transport
HQK30_13960	COG0531	amino acid
HQK30_13975	COG1253	flavin adenine dinucleotide binding
HQK30_13990	COG3547	Transposase (IS116 IS110 IS902 family)
HQK30_13995	COG2801	Transposase and inactivated derivatives
HQK30_14020	COG0704	Plays a role in the regulation of phosphate uptake
HQK30_14025	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
HQK30_14030	COG0581	inorganic phosphate transmembrane transporter activity
HQK30_14035	COG0573	inorganic phosphate transmembrane transporter activity
HQK30_14040	COG0590	tRNA wobble adenosine to inosine editing
HQK30_14055	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
HQK30_14075	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
HQK30_14080	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
HQK30_14085	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
HQK30_14090	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
HQK30_14100	COG3852	Histidine kinase
HQK30_14115	COG2716	regulation of RNA biosynthetic process
HQK30_14120	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
HQK30_14130	COG2239	Acts as a magnesium transporter
HQK30_14145	COG3951	Flagellar rod assembly protein muramidase FlgJ
HQK30_14145	COG1705	Flagellar rod assembly protein muramidase FlgJ
HQK30_14150	COG1706	bacterial-type flagellum-dependent cell motility
HQK30_14155	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
HQK30_14165	COG4787	bacterial-type flagellum-dependent cell motility
HQK30_14185	COG1815	bacterial-type flagellum-dependent cell motility
HQK30_14190	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
HQK30_14195	COG0784	Response regulator, receiver
HQK30_14195	COG0835	chemotaxis
HQK30_14200	COG1261	Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly
HQK30_14215	COG0622	Phosphoesterase
HQK30_14220	COG4166	transmembrane transport
HQK30_14245	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
HQK30_14250	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HQK30_14255	COG1882	Formate acetyltransferase
HQK30_14260	COG1349	DNA-binding transcription factor activity
HQK30_14265	COG0697	spore germination
HQK30_14270	COG4166	transmembrane transport
HQK30_14295	COG1278	Cold shock
HQK30_14335	COG3132	Protein of unknown function, DUF480
HQK30_14350	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
HQK30_14355	COG0438	transferase activity, transferring glycosyl groups
HQK30_14410	COG1091	dTDP-4-dehydrorhamnose reductase activity
HQK30_14425	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HQK30_14430	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HQK30_14435	COG1309	transcriptional regulator
HQK30_14450	COG1946	Acyl-CoA thioesterase
HQK30_14460	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
HQK30_14470	COG0009	L-threonylcarbamoyladenylate synthase
HQK30_14480	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
HQK30_14485	COG0512	Glutamine amidotransferase of anthranilate synthase
HQK30_14485	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
HQK30_14490	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
HQK30_14495	COG0134	indole-3-glycerol-phosphate synthase activity
HQK30_14495	COG0135	phosphoribosylanthranilate isomerase activity
HQK30_14500	COG0133	tryptophan synthase activity
HQK30_14505	COG0159	tryptophan synthase activity
HQK30_14540	COG1988	membrane-bound metal-dependent
HQK30_14545	COG1396	sequence-specific DNA binding
HQK30_14550	COG3550	peptidyl-serine autophosphorylation
HQK30_14570	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
HQK30_14580	COG4521	taurine ABC transporter
HQK30_14585	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
HQK30_14590	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
HQK30_14595	COG2175	clavaminate synthase activity
HQK30_14605	COG2814	Major facilitator Superfamily
HQK30_14610	COG0109	protoheme IX farnesyltransferase activity
HQK30_14615	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
HQK30_14620	COG1845	cytochrome c oxidase, subunit III
HQK30_14625	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
HQK30_14630	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
HQK30_14635	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
HQK30_14680	COG2211	Major facilitator Superfamily
HQK30_14685	COG0071	Belongs to the small heat shock protein (HSP20) family
HQK30_14700	COG0708	Exodeoxyribonuclease III
HQK30_14715	COG2067	long-chain fatty acid transport protein
HQK30_14725	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HQK30_14730	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HQK30_14750	COG0095	Lipoate-protein ligase
HQK30_14780	COG0640	Transcriptional regulator
HQK30_14795	COG1285	pathogenesis
HQK30_14825	COG0484	heat shock protein binding
HQK30_14830	COG0443	Heat shock 70 kDa protein
HQK30_14835	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
HQK30_14840	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
HQK30_14845	COG0497	DNA recombination
HQK30_14850	COG1227	inorganic diphosphatase activity
HQK30_14860	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HQK30_14865	COG1136	(ABC) transporter
HQK30_14865	COG0577	efflux transmembrane transporter activity
HQK30_14875	COG2375	cellular response to nickel ion
HQK30_14880	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
HQK30_14900	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
HQK30_14905	COG1396	sequence-specific DNA binding
HQK30_14905	COG1917	Cupin 2, conserved barrel domain protein
HQK30_14920	COG0531	amino acid
HQK30_14930	COG0531	amino acid
HQK30_14940	COG1283	sodium-dependent phosphate transmembrane transporter activity
HQK30_14950	COG3384	dioxygenase
HQK30_14955	COG5002	protein histidine kinase activity
HQK30_14955	COG0784	Response regulator, receiver
HQK30_14955	COG2205	protein histidine kinase activity
HQK30_14960	COG4251	negative regulation of phosphorylation
HQK30_14960	COG5001	Diguanylate cyclase
HQK30_14960	COG2203	Gaf domain
HQK30_14960	COG3706	GGDEF domain
HQK30_14965	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HQK30_14965	COG2205	protein histidine kinase activity
HQK30_14980	COG0488	(ABC) transporter
HQK30_14995	COG4319	ketosteroid isomerase
HQK30_15000	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
HQK30_15005	COG0083	homoserine kinase activity
HQK30_15015	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
HQK30_15020	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
HQK30_15035	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
HQK30_15045	COG0745	RESPONSE REGULATOR receiver
HQK30_15060	COG4988	ABC transporter
HQK30_15065	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
HQK30_15085	COG1720	tRNA m6t6A37 methyltransferase activity
HQK30_15090	COG3437	response regulator, receiver
HQK30_15090	COG2770	Histidine kinase
HQK30_15105	COG0542	response to heat
HQK30_15110	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
HQK30_15115	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
HQK30_15120	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HQK30_15125	COG2190	(PTS) system
HQK30_15135	COG3038	cytochrome b561
HQK30_15145	COG0420	3'-5' exonuclease activity
HQK30_15155	COG2974	May be involved in recombination
HQK30_15165	COG4651	solute:proton antiporter activity
HQK30_15165	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
HQK30_15180	COG0469	pyruvate kinase activity
HQK30_15185	COG1196	nuclear chromosome segregation
HQK30_15185	COG3264	Mechanosensitive ion channel
HQK30_15195	COG2706	6-phosphogluconolactonase activity
HQK30_15210	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HQK30_15230	COG0281	malic enzyme
HQK30_15240	COG0437	4 iron, 4 sulfur cluster binding
HQK30_15245	COG3383	formate dehydrogenase (NAD+) activity
HQK30_15245	COG3383	formate dehydrogenase (NAD+) activity
HQK30_15280	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
HQK30_15285	COG1910	domain protein
HQK30_15290	COG3852	Histidine kinase
HQK30_15295	COG2204	response regulator
HQK30_15305	COG4662	Binding-protein-dependent transport system inner membrane component
HQK30_15315	COG0746	molybdenum cofactor guanylyltransferase activity
HQK30_15320	COG0303	'Molybdopterin
HQK30_15325	COG1289	transmembrane transporter activity
HQK30_15330	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
HQK30_15360	COG3220	belongs to the UPF0276 family
HQK30_15400	COG2205	protein histidine kinase activity
HQK30_15400	COG0784	Response regulator, receiver
HQK30_15405	COG4166	transmembrane transport
HQK30_15410	COG0601	transmembrane transport
HQK30_15415	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
HQK30_15420	COG0444	Belongs to the ABC transporter superfamily
HQK30_15425	COG4608	Belongs to the ABC transporter superfamily
HQK30_15435	COG2971	BadF BadG BcrA BcrD
HQK30_15445	COG0840	transmembrane signaling receptor activity
HQK30_15465	COG3724	N-succinylarginine dihydrolase activity
HQK30_15470	COG0616	signal peptide processing
HQK30_15475	COG1028	Short-chain dehydrogenase reductase Sdr
HQK30_15480	COG0583	DNA-binding transcription factor activity
HQK30_15490	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
HQK30_15500	COG0583	DNA-binding transcription factor activity
HQK30_15510	COG1881	PFAM PEBP family protein
HQK30_15520	COG3408	Glycogen debranching enzyme
HQK30_15520	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
HQK30_15525	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
HQK30_15530	COG0739	heme binding
HQK30_15535	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
HQK30_15550	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
HQK30_15560	COG3091	SprT-like family
HQK30_15570	COG1385	rRNA (uridine-N3-)-methyltransferase activity
HQK30_15575	COG0189	ligase activity
HQK30_15585	COG1678	Uncharacterized ACR, COG1678
HQK30_15590	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
HQK30_15595	COG3104	oligopeptide transport
HQK30_15605	COG0714	Associated with various cellular activities
HQK30_15620	COG1115	amino acid carrier protein
HQK30_15625	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
HQK30_15640	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
HQK30_15650	COG1301	dicarboxylic acid transport
HQK30_15655	COG2877	3-deoxy-8-phosphooctulonate synthase activity
HQK30_15660	COG2912	Transglutaminase-like superfamily
HQK30_15670	COG2890	protein-(glutamine-N5) methyltransferase activity
HQK30_15675	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
HQK30_15680	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
HQK30_15685	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
HQK30_15690	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
HQK30_15700	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HQK30_15705	COG0737	Belongs to the 5'-nucleotidase family
HQK30_15710	COG0193	aminoacyl-tRNA hydrolase activity
HQK30_15715	COG0012	GTP binding
HQK30_15760	COG0471	metal ion transport
HQK30_15760	COG0490	domain, Protein
HQK30_15800	COG0488	(ABC) transporter
HQK30_15830	COG0674	pyruvate-flavodoxin oxidoreductase activity
HQK30_15830	COG1013	pyruvate-flavodoxin oxidoreductase activity
HQK30_15830	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
HQK30_15830	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
HQK30_15840	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
HQK30_15850	COG1012	belongs to the aldehyde dehydrogenase family
HQK30_15860	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
HQK30_15875	COG0180	Tryptophanyl-tRNA synthetase
HQK30_15885	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
HQK30_15890	COG0338	D12 class N6 adenine-specific DNA methyltransferase
HQK30_15900	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
HQK30_15905	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
HQK30_15935	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
HQK30_15940	COG0583	DNA-binding transcription factor activity
HQK30_15945	COG0840	transmembrane signaling receptor activity
HQK30_15960	COG0583	DNA-binding transcription factor activity
HQK30_15975	COG0739	heme binding
HQK30_15985	COG1511	domain protein
HQK30_15985	COG3264	Mechanosensitive ion channel
HQK30_15990	COG0584	glycerophosphoryl diester phosphodiesterase
HQK30_16000	COG1053	succinate dehydrogenase
HQK30_16005	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
HQK30_16010	COG3029	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
HQK30_16035	COG3214	Protein conserved in bacteria
HQK30_16070	COG0745	RESPONSE REGULATOR receiver
HQK30_16075	COG0642	Histidine kinase
HQK30_16085	COG0516	GMP reductase activity
HQK30_16095	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
HQK30_16100	COG3647	Membrane
HQK30_16110	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HQK30_16120	COG3706	GGDEF domain
HQK30_16130	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
HQK30_16145	COG3706	GGDEF domain
HQK30_16155	COG1335	isochorismatase
HQK30_16160	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
HQK30_16165	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
HQK30_16170	COG1702	phosphate starvation-inducible protein PhoH
HQK30_16175	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
HQK30_16180	COG4535	Mg2 and Co2 transporter CorC
HQK30_16185	COG0815	Transfers the fatty acyl group on membrane lipoproteins
HQK30_16190	COG2888	peptidyl-tyrosine sulfation
HQK30_16195	COG0495	leucyl-tRNA aminoacylation
HQK30_16210	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
HQK30_16215	COG0799	negative regulation of ribosome biogenesis
HQK30_16220	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
HQK30_16225	COG0768	penicillin binding
HQK30_16230	COG0772	Belongs to the SEDS family
HQK30_16235	COG2951	lytic endotransglycosylase activity
HQK30_16245	COG1686	Belongs to the peptidase S11 family
HQK30_16250	COG2921	Belongs to the UPF0250 family
HQK30_16255	COG0321	lipoyl(octanoyl) transferase activity
HQK30_16260	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
HQK30_16265	COG3545	Serine hydrolase
HQK30_16285	COG0789	Transcriptional regulator
HQK30_16290	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
HQK30_16300	COG1970	mechanosensitive ion channel activity
HQK30_16305	COG2203	Gaf domain
HQK30_16305	COG2199	diguanylate cyclase activity
HQK30_16310	COG4974	Belongs to the 'phage' integrase family
HQK30_16320	COG0312	modulator of DNA gyrase
HQK30_16325	COG0312	modulator of DNA gyrase
HQK30_16395	COG0114	fumarate hydratase activity
HQK30_16405	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
HQK30_16410	COG3706	GGDEF domain
HQK30_16415	COG2211	Major facilitator Superfamily
HQK30_16420	COG1185	polyribonucleotide nucleotidyltransferase activity
HQK30_16425	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
HQK30_16430	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
HQK30_16435	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
HQK30_16440	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
HQK30_16445	COG0195	Participates in both transcription termination and antitermination
HQK30_16450	COG0779	Required for maturation of 30S ribosomal subunits
HQK30_16465	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
HQK30_16470	COG0149	triose-phosphate isomerase activity
HQK30_16475	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
HQK30_16480	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
HQK30_16490	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
HQK30_16495	COG1534	Rna-binding protein
HQK30_16510	COG1360	Flagellar Motor Protein
HQK30_16515	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
HQK30_16520	COG1722	exodeoxyribonuclease VII activity
HQK30_16525	COG0142	geranyltranstransferase activity
HQK30_16530	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
HQK30_16550	COG4172	Belongs to the ABC transporter superfamily
HQK30_16555	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
HQK30_16560	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
HQK30_16565	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
HQK30_16570	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
HQK30_16585	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
HQK30_16585	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
HQK30_16590	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
HQK30_16605	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
HQK30_16615	COG0784	Response regulator, receiver
HQK30_16615	COG2198	Histidine kinase
HQK30_16615	COG2205	protein histidine kinase activity
HQK30_16620	COG1879	ABC-type sugar transport system periplasmic component
HQK30_16635	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
HQK30_16645	COG0745	RESPONSE REGULATOR receiver
HQK30_16650	COG3005	denitrification pathway
HQK30_16660	COG3381	protein complex oligomerization
HQK30_16680	COG3300	MHYT domain
HQK30_16680	COG5001	Diguanylate cyclase
HQK30_16690	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
HQK30_16695	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
HQK30_16700	COG0511	ligase activity, forming carbon-carbon bonds
HQK30_16705	COG0439	Biotin carboxylase
HQK30_16710	COG3924	membrane
HQK30_16715	COG4145	pantothenate transmembrane transporter activity
HQK30_16720	COG1263	PTS System
HQK30_16720	COG2190	(PTS) system
HQK30_16720	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HQK30_16725	COG0583	DNA-binding transcription factor activity
HQK30_16730	COG0604	alcohol dehydrogenase
HQK30_16735	COG2264	protein methyltransferase activity
HQK30_16750	COG0778	Nitroreductase
HQK30_16755	COG1902	pentaerythritol trinitrate reductase activity
HQK30_16755	COG0446	pyridine nucleotide-disulphide oxidoreductase
HQK30_16760	COG0616	signal peptide processing
HQK30_16780	COG3139	Protein of unknown function (DUF1315)
HQK30_16785	COG0252	asparaginase activity
HQK30_16790	COG0786	glutamate:sodium symporter activity
HQK30_16805	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
HQK30_16810	COG0384	phenazine biosynthesis protein PhzF
HQK30_16815	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
HQK30_16820	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
HQK30_16825	COG0175	sulfate reduction
HQK30_16830	COG2113	Glycine betaine
HQK30_16835	COG4176	ABC-type proline glycine betaine transport system permease component
HQK30_16840	COG4175	Glycine betaine
HQK30_16850	COG3610	response to peptide
HQK30_16855	COG2966	Psort location CytoplasmicMembrane, score
HQK30_16865	COG0521	Mo-molybdopterin cofactor biosynthetic process
HQK30_16875	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
HQK30_16880	COG1028	Short-chain dehydrogenase reductase Sdr
HQK30_16890	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
HQK30_16915	COG2986	histidine ammonia-lyase
HQK30_16940	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
HQK30_16945	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
HQK30_16980	COG1858	cytochrome C peroxidase
HQK30_16990	COG2313	pseudouridylate synthase activity
HQK30_16995	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HQK30_17020	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
HQK30_17040	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
HQK30_17045	COG2195	Cleaves the N-terminal amino acid of tripeptides
HQK30_17050	COG4608	Belongs to the ABC transporter superfamily
HQK30_17055	COG0444	Belongs to the ABC transporter superfamily
HQK30_17065	COG4239	(ABC) transporter, permease
HQK30_17070	COG4174	ABC transporter (Permease)
HQK30_17085	COG0811	peptide transport
HQK30_17090	COG0811	peptide transport
HQK30_17095	COG0848	biopolymer transport protein
HQK30_17145	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
HQK30_17150	COG0840	transmembrane signaling receptor activity
HQK30_17160	COG1278	Cold shock
HQK30_17200	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
HQK30_17205	COG1162	GTPase activity
HQK30_17210	COG0688	phosphatidylethanolamine metabolic process
HQK30_17215	COG4628	conserved protein (DUF2132)
HQK30_17235	COG5001	Diguanylate cyclase
HQK30_17235	COG3300	MHYT domain
HQK30_17240	COG3076	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome
HQK30_17265	COG1132	(ABC) transporter
HQK30_17275	COG1404	Belongs to the peptidase S8 family
HQK30_17280	COG2897	thiosulfate sulfurtransferase activity
HQK30_17285	COG2066	Belongs to the glutaminase family
HQK30_17290	COG3171	Protein conserved in bacteria
HQK30_17295	COG0220	tRNA (guanine-N7-)-methyltransferase activity
HQK30_17300	COG2234	aminopeptidase activity
HQK30_17300	COG4935	Belongs to the peptidase S8 family
HQK30_17305	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HQK30_17310	COG2200	EAL domain
HQK30_17315	COG1090	epimerase
HQK30_17320	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
HQK30_17325	COG4181	ATPase activity
HQK30_17330	COG2755	lipolytic protein G-D-S-L family
HQK30_17335	COG0835	chemotaxis
HQK30_17335	COG0784	Response regulator, receiver
HQK30_17360	COG2985	domain, Protein
HQK30_17360	COG0569	domain protein
HQK30_17365	COG1272	protein, Hemolysin III
HQK30_17370	COG0076	glutamate decarboxylase activity
HQK30_17375	COG2917	probably involved in intracellular septation
HQK30_17380	COG2350	Protein conserved in bacteria
HQK30_17390	COG1555	photosystem II stabilization
HQK30_17395	COG1210	Utp--glucose-1-phosphate uridylyltransferase
HQK30_17400	COG3104	oligopeptide transport
HQK30_17405	COG0745	RESPONSE REGULATOR receiver
HQK30_17435	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HQK30_17450	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
HQK30_17480	COG0316	Belongs to the HesB IscA family
HQK30_17490	COG0038	chloride channel
HQK30_17495	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
HQK30_17510	COG0671	phosphoesterase, PA-phosphatase related
HQK30_17520	COG3437	response regulator, receiver
HQK30_17520	COG0784	Response regulator, receiver
HQK30_17530	COG2076	Multidrug Resistance protein
HQK30_17540	COG0346	lactoylglutathione lyase activity
HQK30_17545	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
HQK30_17550	COG1643	Atp-dependent helicase
HQK30_17560	COG1489	DNA binding
HQK30_17565	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
HQK30_17570	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
HQK30_17585	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
HQK30_17590	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
HQK30_17610	COG1924	4 iron, 4 sulfur cluster binding
HQK30_17615	COG1775	2-hydroxyglutaryl-CoA dehydratase, D-component
HQK30_17620	COG0842	Transport permease protein
HQK30_17625	COG1131	(ABC) transporter
HQK30_17640	COG0163	prenyltransferase activity
HQK30_17645	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
HQK30_17650	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
HQK30_17665	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
HQK30_17680	COG1136	(ABC) transporter
HQK30_17700	COG0840	transmembrane signaling receptor activity
HQK30_17715	COG0529	Catalyzes the synthesis of activated sulfate
HQK30_17720	COG0471	metal ion transport
HQK30_17720	COG3273	potassium ion transport
HQK30_17725	COG2895	sulfate adenylyltransferase (ATP) activity
HQK30_17730	COG0175	sulfate reduction
HQK30_17735	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
HQK30_17735	COG1648	precorrin-2 dehydrogenase activity
HQK30_17740	COG0330	HflC and HflK could
HQK30_17745	COG1585	Membrane protein implicated in regulation of membrane protease activity
HQK30_17750	COG0517	IMP dehydrogenase activity
HQK30_17750	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
HQK30_17755	COG0488	(ABC) transporter
HQK30_17765	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
HQK30_17790	COG2801	Transposase and inactivated derivatives
HQK30_17805	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HQK30_17815	COG0668	transmembrane transport
HQK30_17825	COG2731	YhcH YjgK YiaL family protein
HQK30_17840	COG1794	racemase activity, acting on amino acids and derivatives
HQK30_17855	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HQK30_17880	COG0733	neurotransmitter:sodium symporter activity
HQK30_17890	COG0733	neurotransmitter:sodium symporter activity
HQK30_17905	COG0561	phosphatase activity
HQK30_17935	COG1846	Transcriptional regulator
HQK30_17940	COG2130	NADP-dependent
HQK30_17945	COG1051	belongs to the nudix hydrolase family
HQK30_17965	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
HQK30_17970	COG1640	4-alpha-glucanotransferase
HQK30_17975	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
HQK30_17980	COG0676	glucose-6-phosphate 1-epimerase activity
HQK30_17985	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
HQK30_17990	COG0840	transmembrane signaling receptor activity
HQK30_18065	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
HQK30_18070	COG2885	chlorophyll binding
HQK30_18075	COG0823	Involved in the tonB-independent uptake of proteins
HQK30_18090	COG0811	peptide transport
HQK30_18095	COG0824	Thioesterase
HQK30_18100	COG3790	cyd operon protein YbgE
HQK30_18105	COG4890	Cyd operon protein YbgT
HQK30_18110	COG1294	oxidase, subunit
HQK30_18115	COG1271	oxidase subunit
HQK30_18120	COG2255	four-way junction helicase activity
HQK30_18125	COG0632	four-way junction helicase activity
HQK30_18130	COG0840	transmembrane signaling receptor activity
HQK30_18135	COG0442	prolyl-tRNA aminoacylation
HQK30_18140	COG4221	oxidoreductase activity
HQK30_18155	COG1024	Enoyl-CoA hydratase
HQK30_18165	COG0110	maltose O-acetyltransferase activity
HQK30_18175	COG4166	transmembrane transport
HQK30_18190	COG1872	DUF167
HQK30_18195	COG0762	integral membrane protein
HQK30_18200	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HQK30_18205	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
HQK30_18215	COG2805	Type II/IV secretion system protein
HQK30_18220	COG3022	response to hydroperoxide
HQK30_18225	COG0513	Belongs to the DEAD box helicase family
HQK30_18230	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
HQK30_18255	COG0735	belongs to the Fur family
HQK30_18260	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HQK30_18275	COG0776	regulation of translation
HQK30_18305	COG0560	Phosphoserine phosphatase
HQK30_18315	COG3447	MASE1 domain protein
HQK30_18315	COG5001	Diguanylate cyclase
HQK30_18315	COG5002	protein histidine kinase activity
HQK30_18320	COG0813	purine-nucleoside phosphorylase activity
HQK30_18325	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
HQK30_18330	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
HQK30_18335	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
HQK30_18345	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
HQK30_18350	COG0084	hydrolase, TatD family'
HQK30_18370	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HQK30_18375	COG0004	ammonium transporteR
HQK30_18405	COG0795	lipopolysaccharide-transporting ATPase activity
HQK30_18410	COG0795	lipopolysaccharide-transporting ATPase activity
HQK30_18415	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
HQK30_18420	COG2927	DNA polymerase III (CHI subunit)
HQK30_18425	COG0525	valine-tRNA ligase activity
HQK30_18430	COG1253	flavin adenine dinucleotide binding
HQK30_18435	COG0586	Pfam SNARE associated Golgi protein
HQK30_18440	COG1686	Belongs to the peptidase S11 family
HQK30_18475	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
HQK30_18480	COG0527	aspartate kinase activity
HQK30_18485	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
HQK30_18495	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
HQK30_18500	COG1546	Belongs to the CinA family
HQK30_18505	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
HQK30_18525	COG3068	Protein conserved in bacteria
HQK30_18535	COG0739	heme binding
HQK30_18555	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
HQK30_18560	COG1121	(ABC) transporter
HQK30_18565	COG1108	ABC-type Mn2 Zn2 transport systems permease components
HQK30_18570	COG0583	DNA-binding transcription factor activity
HQK30_18575	COG0697	spore germination
HQK30_18580	COG1573	uracil-dna glycosylase
HQK30_18585	COG2962	Rard protein
HQK30_18595	COG2827	Endonuclease containing a URI domain
HQK30_18610	COG1842	Phage shock protein A
HQK30_18615	COG0204	Acyl-transferase
HQK30_18635	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
HQK30_18700	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
HQK30_18710	COG0583	DNA-binding transcription factor activity
HQK30_18730	COG1289	transmembrane transporter activity
HQK30_18735	COG1566	PFAM secretion protein HlyD family protein
HQK30_18750	COG1051	belongs to the nudix hydrolase family
HQK30_18755	COG3150	esterase
HQK30_18765	COG3151	Protein conserved in bacteria
HQK30_18770	COG0494	nUDIX hydrolase
HQK30_18775	COG1538	Outer membrane efflux protein
HQK30_18780	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
HQK30_18780	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
HQK30_18785	COG1560	Kdo2-lipid A biosynthetic process
HQK30_18800	COG1392	Phosphate transport regulator
HQK30_18805	COG0306	phosphate transporter
HQK30_18810	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
HQK30_18840	COG0583	DNA-binding transcription factor activity
HQK30_18845	COG1380	Effector of murein hydrolase LrgA
HQK30_18850	COG1346	cytolysis
HQK30_18865	COG0617	tRNA 3'-terminal CCA addition
HQK30_18870	COG3267	Type II secretory pathway component ExeA
HQK30_18870	COG3409	Peptidoglycan-binding domain 1 protein
HQK30_18880	COG1194	a g-specific adenine glycosylase
HQK30_18885	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
HQK30_18895	COG3111	PFAM Bacterial OB fold (BOF) protein
HQK30_18900	COG3240	lipase activity
HQK30_18915	COG3009	Protein conserved in bacteria
HQK30_18920	COG3008	intermembrane lipid transfer
HQK30_18920	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
HQK30_18925	COG2995	paraquat-inducible protein a
HQK30_18935	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
HQK30_18945	COG4251	negative regulation of phosphorylation
HQK30_18945	COG3706	GGDEF domain
HQK30_18945	COG5001	Diguanylate cyclase
HQK30_18945	COG2203	Gaf domain
HQK30_18950	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HQK30_18955	COG2813	Specifically methylates the guanine in position
HQK30_18960	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
HQK30_18965	COG0297	glycogen (starch) synthase activity
HQK30_19000	COG1757	Na H antiporter
HQK30_19005	COG0583	DNA-binding transcription factor activity
HQK30_19010	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
HQK30_19015	COG3842	ATPase activity
HQK30_19020	COG1176	ABC-type spermidine putrescine transport system, permease component I
HQK30_19025	COG1177	transmembrane transport
HQK30_19030	COG1012	belongs to the aldehyde dehydrogenase family
HQK30_19055	COG0110	maltose O-acetyltransferase activity
HQK30_19060	COG0366	Alpha amylase catalytic
HQK30_19065	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HQK30_19065	COG1263	PTS System
HQK30_19070	COG1609	Transcriptional regulator
HQK30_19085	COG0252	asparaginase activity
HQK30_19100	COG1803	Methylglyoxal synthase
HQK30_19125	COG1444	tRNA N-acetyltransferase activity
HQK30_19130	COG1028	Short-chain dehydrogenase reductase Sdr
HQK30_19135	COG0835	chemotaxis
HQK30_19135	COG0784	Response regulator, receiver
HQK30_19180	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
HQK30_19185	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
HQK30_19200	COG0477	Major facilitator Superfamily
HQK30_19205	COG0523	cobalamin synthesis protein
HQK30_19215	COG1280	lysine exporter protein (LysE YggA)
HQK30_19225	COG2200	EAL domain
HQK30_19230	COG1049	propionate catabolic process, 2-methylcitrate cycle
HQK30_19235	COG1752	Esterase of the alpha-beta hydrolase superfamily
HQK30_19240	COG0840	transmembrane signaling receptor activity
HQK30_19245	COG0840	transmembrane signaling receptor activity
HQK30_19255	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
HQK30_19260	COG0508	dehydrogenase complex catalyzes the overall conversion of
HQK30_19265	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
HQK30_19270	COG2186	Transcriptional regulator
HQK30_19295	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
HQK30_19300	COG1459	type II secretion system
HQK30_19315	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
HQK30_19320	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
HQK30_19325	COG0494	nUDIX hydrolase
HQK30_19335	COG0653	protein targeting
HQK30_19345	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
HQK30_19350	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
HQK30_19355	COG0849	cell division
HQK30_19360	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
HQK30_19365	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
HQK30_19370	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
HQK30_19375	COG0772	Belongs to the SEDS family
HQK30_19380	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
HQK30_19390	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
HQK30_19400	COG0768	penicillin binding
HQK30_19405	COG3116	cell division
HQK30_19410	COG0275	rRNA processing
HQK30_19415	COG2001	Belongs to the MraZ family
HQK30_19425	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
HQK30_19430	COG3107	peptidoglycan biosynthetic process
HQK30_19435	COG0792	nuclease activity
HQK30_19440	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
HQK30_19445	COG2823	Periplasmic or secreted lipoprotein
HQK30_19450	COG2969	positive regulation of protein catabolic process
HQK30_19455	COG0625	glutathione transferase activity
HQK30_19460	COG2857	Cytochrome c1
HQK30_19465	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
HQK30_19470	COG0723	plastoquinol--plastocyanin reductase activity
HQK30_19475	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
HQK30_19480	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
HQK30_19485	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
HQK30_19495	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HQK30_19500	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HQK30_19530	COG3964	amidohydrolase
HQK30_19545	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
HQK30_19545	COG3711	transcriptional antiterminator
HQK30_19550	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
HQK30_19555	COG1660	Displays ATPase and GTPase activities
HQK30_19560	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
HQK30_19570	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
HQK30_19575	COG1137	ATPase activity
HQK30_19580	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
HQK30_19585	COG3117	lipopolysaccharide transmembrane transporter activity
HQK30_19590	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
HQK30_19595	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
HQK30_19595	COG0517	IMP dehydrogenase activity
HQK30_19600	COG1127	ABC transporter
HQK30_19605	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
HQK30_19610	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
HQK30_19615	COG2854	intermembrane phospholipid transfer
HQK30_19625	COG5007	Belongs to the BolA IbaG family
HQK30_19630	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HQK30_19635	COG0312	modulator of DNA gyrase
HQK30_19640	COG3028	Belongs to the UPF0307 family
HQK30_19650	COG2926	Belongs to the UPF0265 family
HQK30_19680	COG1396	sequence-specific DNA binding
HQK30_19685	COG3135	benzoate transporter
HQK30_19710	COG0840	transmembrane signaling receptor activity
HQK30_19715	COG3047	cAMP biosynthetic process
HQK30_19720	COG3706	GGDEF domain
HQK30_19725	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
HQK30_19730	COG2197	response regulator
HQK30_19760	COG4771	TonB-dependent receptor
HQK30_19765	COG2203	Gaf domain
HQK30_19765	COG3706	GGDEF domain
HQK30_19765	COG4251	negative regulation of phosphorylation
HQK30_19765	COG5001	Diguanylate cyclase
HQK30_19775	COG0745	RESPONSE REGULATOR receiver
HQK30_19810	COG0346	lactoylglutathione lyase activity
HQK30_19820	COG0583	DNA-binding transcription factor activity
HQK30_19830	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
HQK30_19835	COG1074	ATP-dependent DNA helicase activity
HQK30_19840	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
HQK30_19845	COG2259	Doxx family
HQK30_19850	COG1741	Belongs to the pirin family
HQK30_19860	COG0583	DNA-binding transcription factor activity
HQK30_19885	COG1175	transmembrane transport
HQK30_19895	COG3842	ATPase activity
HQK30_19905	COG3706	GGDEF domain
HQK30_19925	COG1247	-acetyltransferase
HQK30_19950	COG0671	phosphoesterase, PA-phosphatase related
HQK30_19955	COG0628	permease
HQK30_19960	COG4221	oxidoreductase activity
HQK30_19965	COG2957	Belongs to the agmatine deiminase family
HQK30_19970	COG0583	DNA-binding transcription factor activity
HQK30_19975	COG3284	Transcriptional regulator
HQK30_19990	COG1461	Dihydroxyacetone kinase
HQK30_19995	COG2376	Dihydroxyacetone kinase
HQK30_20000	COG2252	PERMEase
HQK30_20035	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
HQK30_20040	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
HQK30_20045	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
HQK30_20050	COG0049	tRNA binding
HQK30_20055	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
HQK30_20060	COG2168	tRNA wobble position uridine thiolation
HQK30_20075	COG0251	oxidation-reduction process
HQK30_20080	COG2964	Protein conserved in bacteria
HQK30_20085	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HQK30_20090	COG0085	RNA polymerase activity
HQK30_20095	COG0222	ribosome binding
HQK30_20100	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
HQK30_20105	COG0081	regulation of translation
HQK30_20110	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
HQK30_20115	COG0250	Participates in transcription elongation, termination and antitermination
HQK30_20130	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
HQK30_20155	COG0812	UDP-N-acetylmuramate dehydrogenase activity
HQK30_20160	COG0569	domain protein
HQK30_20165	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
HQK30_20185	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HQK30_20190	COG3005	denitrification pathway
HQK30_20195	COG0243	molybdopterin cofactor binding
HQK30_20205	COG2205	protein histidine kinase activity
HQK30_20210	COG0745	RESPONSE REGULATOR receiver
HQK30_20225	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
HQK30_20240	COG2204	response regulator
HQK30_20250	COG2205	protein histidine kinase activity
HQK30_20265	COG1028	Short-chain dehydrogenase reductase Sdr
HQK30_20270	COG0617	tRNA 3'-terminal CCA addition
HQK30_20270	COG3620	sequence-specific DNA binding
HQK30_20270	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
HQK30_20275	COG5413	integral membrane protein
HQK30_20285	COG1522	sequence-specific DNA binding
HQK30_20290	COG2502	aspartate--ammonia ligase
HQK30_20295	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
HQK30_20300	COG0542	response to heat
HQK30_20310	COG0564	pseudouridine synthase activity
HQK30_20315	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
HQK30_20320	COG0446	pyridine nucleotide-disulphide oxidoreductase
HQK30_20330	COG3681	Belongs to the UPF0597 family
HQK30_20340	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
HQK30_20345	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
HQK30_20350	COG1979	alcohol dehydrogenase
HQK30_20355	COG2207	Transcriptional regulator
HQK30_20360	COG3040	lipid binding
HQK30_20375	COG0688	phosphatidylethanolamine metabolic process
HQK30_20395	COG0540	Belongs to the ATCase OTCase family
HQK30_20400	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
HQK30_20405	COG1438	arginine binding
HQK30_20410	COG1288	antiporter activity
HQK30_20415	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
HQK30_20465	COG3250	beta-galactosidase activity
HQK30_20470	COG1609	Transcriptional regulator
HQK30_20475	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
HQK30_20485	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
HQK30_20490	COG2017	converts alpha-aldose to the beta-anomer
HQK30_20495	COG0667	Aldo Keto reductase
HQK30_20500	COG1968	undecaprenyl-diphosphatase activity
HQK30_20505	COG3806	Anti-sigma factor
HQK30_20510	COG1595	DNA-templated transcription, initiation
HQK30_20520	COG0018	arginyl-trna synthetase
HQK30_20530	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
HQK30_20535	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
HQK30_20540	COG0477	Major facilitator Superfamily
HQK30_20550	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
HQK30_20560	COG2116	formate transmembrane transporter activity
HQK30_20565	COG1648	precorrin-2 dehydrogenase activity
HQK30_20565	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
HQK30_20570	COG2239	Acts as a magnesium transporter
HQK30_20580	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
HQK30_20585	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
HQK30_20595	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
HQK30_20605	COG0514	ATP-dependent DNA helicase (RecQ)
HQK30_20610	COG2050	protein possibly involved in aromatic compounds catabolism
HQK30_20625	COG2258	MOSC domain
HQK30_20630	COG1177	transmembrane transport
HQK30_20635	COG1176	ABC-type spermidine putrescine transport system, permease component I
HQK30_20640	COG3842	ATPase activity
HQK30_20660	COG0174	glutamine synthetase
HQK30_20680	COG3045	CreA protein
HQK30_20685	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HQK30_20690	COG0443	Heat shock 70 kDa protein
HQK30_20695	COG3187	Heat shock protein
HQK30_20705	COG0366	Alpha amylase catalytic
HQK30_20710	COG1086	Polysaccharide biosynthesis protein
HQK30_20715	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
HQK30_20735	COG0367	asparagine synthase
HQK30_20740	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
HQK30_20765	COG1215	transferase activity, transferring glycosyl groups
HQK30_20780	COG0318	PFAM AMP-dependent synthetase and ligase
HQK30_20785	COG1028	Short-chain dehydrogenase reductase Sdr
HQK30_20800	COG1083	cytidylyl-transferase
HQK30_20810	COG2089	acid synthase
HQK30_20830	COG4310	Domain of unknown function (DUF2172)
HQK30_20865	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HQK30_20870	COG0745	RESPONSE REGULATOR receiver
HQK30_20875	COG2205	protein histidine kinase activity
HQK30_20885	COG0281	malic enzyme
HQK30_20890	COG0702	epimerase
HQK30_20895	COG0254	rRNA binding
HQK30_20900	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
HQK30_20930	COG0129	dihydroxy-acid dehydratase activity
HQK30_20940	COG3978	acetolactate synthase activity
HQK30_20950	COG0606	chelatase, subunit chli
HQK30_20955	COG0204	Acyl-transferase
HQK30_20960	COG0204	Acyl-transferase
HQK30_20965	COG1683	Conserved Protein
HQK30_20975	COG1335	isochorismatase
HQK30_20985	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
HQK30_20990	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
HQK30_20995	COG3639	organic phosphonate transmembrane transporter activity
HQK30_21000	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
HQK30_21005	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
HQK30_21015	COG3084	Protein conserved in bacteria
HQK30_21020	COG4251	negative regulation of phosphorylation
HQK30_21020	COG5001	Diguanylate cyclase
HQK30_21020	COG2203	Gaf domain
HQK30_21020	COG3706	GGDEF domain
HQK30_21025	COG0789	Transcriptional regulator
HQK30_21035	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
HQK30_21040	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
HQK30_21045	COG1561	YicC-like family, N-terminal region
HQK30_21070	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HQK30_21090	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HQK30_21095	COG4605	iron ion homeostasis
HQK30_21100	COG4604	ABC transporter, ATP-binding protein
HQK30_21105	COG4607	ABC-type enterochelin transport system periplasmic component
HQK30_21110	COG4774	siderophore transport
HQK30_21130	COG3306	glycosyltransferase involved in LPS biosynthesis
HQK30_21145	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
HQK30_21160	COG1063	alcohol dehydrogenase
HQK30_21165	COG3245	cytochrome
HQK30_21170	COG3300	MHYT domain
HQK30_21170	COG5001	Diguanylate cyclase
HQK30_21180	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
HQK30_21185	COG2166	iron-sulfur cluster assembly
HQK30_21190	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
HQK30_21225	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
HQK30_21230	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
HQK30_21235	COG1739	Uncharacterized protein family UPF0029
HQK30_21240	COG0006	proline dipeptidase activity
HQK30_21245	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
HQK30_21250	COG1024	Enoyl-CoA hydratase
HQK30_21250	COG1250	3-hydroxyacyl-CoA dehydrogenase
HQK30_21255	COG0183	Belongs to the thiolase family
HQK30_21260	COG0745	RESPONSE REGULATOR receiver
HQK30_21265	COG2205	protein histidine kinase activity
HQK30_21280	COG0425	Belongs to the sulfur carrier protein TusA family
HQK30_21285	COG0251	oxidation-reduction process
HQK30_21295	COG2885	chlorophyll binding
HQK30_21305	COG2818	Glycosylase
HQK30_21310	COG0752	glycyl-tRNA synthetase alpha subunit
HQK30_21315	COG0751	glycine-tRNA ligase activity
HQK30_21350	COG0814	amino acid
HQK30_21355	COG0348	domain, Protein
HQK30_21365	COG0446	pyridine nucleotide-disulphide oxidoreductase
HQK30_21370	COG0426	domain, Protein
HQK30_21370	COG1773	rubredoxin
HQK30_21375	COG3604	Transcriptional regulator
HQK30_21380	COG2188	Transcriptional regulator
HQK30_21395	COG1609	Transcriptional regulator
HQK30_21435	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HQK30_21460	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
HQK30_21475	COG3118	belongs to the thioredoxin family
HQK30_21480	COG0513	Belongs to the DEAD box helicase family
HQK30_21485	COG0248	Ppx GppA phosphatase
HQK30_21500	COG0742	ribosomal rna small subunit methyltransferase
HQK30_21505	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HQK30_21525	COG0084	hydrolase, TatD family'
HQK30_21530	COG0805	protein transport
HQK30_21535	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
HQK30_21545	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
HQK30_21550	COG3165	ubiquinone biosynthetic process from chorismate
HQK30_21560	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HQK30_21565	COG0402	S-adenosylhomocysteine deaminase activity
HQK30_21610	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
HQK30_21615	COG0848	biopolymer transport protein
HQK30_21620	COG0811	peptide transport
HQK30_21625	COG0811	peptide transport
HQK30_21635	COG2771	luxR family
HQK30_21640	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
HQK30_21645	COG1349	DNA-binding transcription factor activity
HQK30_21650	COG0745	RESPONSE REGULATOR receiver
HQK30_21655	COG2205	protein histidine kinase activity
HQK30_21665	COG4452	Inner membrane protein CreD
HQK30_21670	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
HQK30_21675	COG0355	proton-transporting ATP synthase activity, rotational mechanism
HQK30_21680	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
HQK30_21685	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
HQK30_21690	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
HQK30_21695	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HQK30_21700	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
HQK30_21710	COG0356	it plays a direct role in the translocation of protons across the membrane
HQK30_21720	COG1475	DNA binding
HQK30_21725	COG1192	Involved in chromosome partitioning
HQK30_21730	COG0357	Ribosomal RNA small subunit methyltransferase G
HQK30_21735	COG0445	tRNA wobble uridine modification
HQK30_21740	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
HQK30_21745	COG4774	siderophore transport
HQK30_21750	COG4615	Cyclic peptide transporter
HQK30_21755	COG1120	ATPase activity
HQK30_21770	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
HQK30_21775	COG0706	membrane insertase activity
HQK30_21780	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
HQK30_21785	COG0594	ribonuclease P activity
HQK30_21790	COG0230	Belongs to the bacterial ribosomal protein bL34 family
HQK30_21795	COG1126	abc transporter atp-binding protein