locus-tag	class	description
NRZ29_00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
NRZ29_00010	COG0592	DNA-directed DNA polymerase activity
NRZ29_00015	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
NRZ29_00030	COG2378	regulation of single-species biofilm formation
NRZ29_00040	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
NRZ29_00045	COG0071	Belongs to the small heat shock protein (HSP20) family
NRZ29_00050	COG0071	Belongs to the small heat shock protein (HSP20) family
NRZ29_00055	COG3977	Valine--pyruvate aminotransferase
NRZ29_00070	COG2814	Major facilitator Superfamily
NRZ29_00075	COG0745	RESPONSE REGULATOR receiver
NRZ29_00080	COG2205	protein histidine kinase activity
NRZ29_00100	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
NRZ29_00105	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
NRZ29_00105	COG4191	Histidine kinase
NRZ29_00110	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
NRZ29_00115	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NRZ29_00120	COG1309	transcriptional regulator
NRZ29_00150	COG0469	pyruvate kinase activity
NRZ29_00155	COG2271	Major facilitator Superfamily
NRZ29_00180	COG0561	phosphatase activity
NRZ29_00185	COG2267	carboxylic ester hydrolase activity
NRZ29_00195	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
NRZ29_00200	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
NRZ29_00205	COG1758	RNA polymerase activity
NRZ29_00215	COG0859	PFAM glycosyl transferase family 9
NRZ29_00220	COG3642	lipopolysaccharide core region biosynthetic process
NRZ29_00260	COG0589	response to stress
NRZ29_00265	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
NRZ29_00275	COG1528	Iron-storage protein
NRZ29_00280	COG2081	HI0933 family
NRZ29_00285	COG2223	nitrite transmembrane transporter activity
NRZ29_00290	COG1280	lysine exporter protein (LysE YggA)
NRZ29_00310	COG3188	usher protein
NRZ29_00330	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
NRZ29_00330	COG2205	protein histidine kinase activity
NRZ29_00340	COG3275	phosphorelay sensor kinase activity
NRZ29_00345	COG3279	Response regulator of the LytR AlgR family
NRZ29_00350	COG2223	nitrite transmembrane transporter activity
NRZ29_00355	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
NRZ29_00360	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
NRZ29_00375	COG0583	DNA-binding transcription factor activity
NRZ29_00380	COG4206	TonB-dependent receptor
NRZ29_00385	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
NRZ29_00420	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
NRZ29_00425	COG2166	iron-sulfur cluster assembly
NRZ29_00430	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
NRZ29_00445	COG3245	cytochrome
NRZ29_00450	COG1063	alcohol dehydrogenase
NRZ29_00455	COG0156	8-amino-7-oxononanoate synthase activity
NRZ29_00465	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
NRZ29_00480	COG3306	glycosyltransferase involved in LPS biosynthesis
NRZ29_00500	COG4774	siderophore transport
NRZ29_00505	COG4607	ABC-type enterochelin transport system periplasmic component
NRZ29_00510	COG4604	ABC transporter, ATP-binding protein
NRZ29_00515	COG4605	iron ion homeostasis
NRZ29_00520	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NRZ29_00525	COG1132	(ABC) transporter
NRZ29_00530	COG2375	cellular response to nickel ion
NRZ29_00530	COG1132	(ABC) transporter
NRZ29_00540	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
NRZ29_00550	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
NRZ29_00560	COG0076	glutamate decarboxylase activity
NRZ29_00565	COG1561	YicC-like family, N-terminal region
NRZ29_00570	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
NRZ29_00575	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
NRZ29_00590	COG2203	Gaf domain
NRZ29_00590	COG4251	negative regulation of phosphorylation
NRZ29_00590	COG5001	Diguanylate cyclase
NRZ29_00590	COG3706	GGDEF domain
NRZ29_00595	COG3084	Protein conserved in bacteria
NRZ29_00605	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
NRZ29_00610	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
NRZ29_00620	COG1335	isochorismatase
NRZ29_00630	COG1683	Conserved Protein
NRZ29_00635	COG0204	Acyl-transferase
NRZ29_00640	COG0204	Acyl-transferase
NRZ29_00645	COG0606	chelatase, subunit chli
NRZ29_00655	COG3978	acetolactate synthase activity
NRZ29_00665	COG0129	dihydroxy-acid dehydratase activity
NRZ29_00685	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
NRZ29_00690	COG0254	rRNA binding
NRZ29_00695	COG0702	epimerase
NRZ29_00700	COG0281	malic enzyme
NRZ29_00710	COG2205	protein histidine kinase activity
NRZ29_00715	COG0745	RESPONSE REGULATOR receiver
NRZ29_00720	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
NRZ29_00755	COG4310	Domain of unknown function (DUF2172)
NRZ29_00775	COG2089	acid synthase
NRZ29_00785	COG1083	cytidylyl-transferase
NRZ29_00800	COG1028	Short-chain dehydrogenase reductase Sdr
NRZ29_00805	COG0318	PFAM AMP-dependent synthetase and ligase
NRZ29_00820	COG1215	transferase activity, transferring glycosyl groups
NRZ29_00825	COG0562	UDP-galactopyranose mutase
NRZ29_00845	COG2226	methyltransferase
NRZ29_00850	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
NRZ29_00855	COG1086	Polysaccharide biosynthesis protein
NRZ29_00860	COG0366	Alpha amylase catalytic
NRZ29_00875	COG0443	Heat shock 70 kDa protein
NRZ29_00880	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NRZ29_00885	COG3045	CreA protein
NRZ29_00905	COG0174	glutamine synthetase
NRZ29_00925	COG3842	ATPase activity
NRZ29_00930	COG1176	ABC-type spermidine putrescine transport system, permease component I
NRZ29_00935	COG1177	transmembrane transport
NRZ29_00940	COG2258	MOSC domain
NRZ29_00955	COG2050	protein possibly involved in aromatic compounds catabolism
NRZ29_00960	COG0514	ATP-dependent DNA helicase (RecQ)
NRZ29_00970	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
NRZ29_00980	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
NRZ29_00985	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
NRZ29_00995	COG2239	Acts as a magnesium transporter
NRZ29_01000	COG1648	precorrin-2 dehydrogenase activity
NRZ29_01000	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
NRZ29_01005	COG2116	formate transmembrane transporter activity
NRZ29_01020	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
NRZ29_01025	COG0842	Transport permease protein
NRZ29_01030	COG0842	Transport permease protein
NRZ29_01035	COG1131	(ABC) transporter
NRZ29_01040	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NRZ29_01050	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
NRZ29_01055	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
NRZ29_01075	COG1595	DNA-templated transcription, initiation
NRZ29_01080	COG3806	Anti-sigma factor
NRZ29_01085	COG1968	undecaprenyl-diphosphatase activity
NRZ29_01090	COG0667	Aldo Keto reductase
NRZ29_01095	COG2017	converts alpha-aldose to the beta-anomer
NRZ29_01100	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
NRZ29_01110	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
NRZ29_01115	COG1609	Transcriptional regulator
NRZ29_01120	COG3250	beta-galactosidase activity
NRZ29_01170	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
NRZ29_01175	COG1288	antiporter activity
NRZ29_01180	COG1438	arginine binding
NRZ29_01185	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
NRZ29_01190	COG0540	Belongs to the ATCase OTCase family
NRZ29_01210	COG0688	phosphatidylethanolamine metabolic process
NRZ29_01220	COG3040	lipid binding
NRZ29_01225	COG2207	Transcriptional regulator
NRZ29_01230	COG1979	alcohol dehydrogenase
NRZ29_01235	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
NRZ29_01240	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
NRZ29_01250	COG3681	Belongs to the UPF0597 family
NRZ29_01260	COG0446	pyridine nucleotide-disulphide oxidoreductase
NRZ29_01265	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
NRZ29_01270	COG0564	pseudouridine synthase activity
NRZ29_01280	COG0542	response to heat
NRZ29_01285	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
NRZ29_01290	COG2502	aspartate--ammonia ligase
NRZ29_01295	COG1522	sequence-specific DNA binding
NRZ29_01305	COG5413	integral membrane protein
NRZ29_01330	COG2205	protein histidine kinase activity
NRZ29_01340	COG2204	response regulator
NRZ29_01355	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
NRZ29_01385	COG0243	molybdopterin cofactor binding
NRZ29_01390	COG3005	denitrification pathway
NRZ29_01395	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
NRZ29_01415	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
NRZ29_01420	COG0569	domain protein
NRZ29_01425	COG0812	UDP-N-acetylmuramate dehydrogenase activity
NRZ29_01450	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
NRZ29_01465	COG0250	Participates in transcription elongation, termination and antitermination
NRZ29_01470	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
NRZ29_01475	COG0081	regulation of translation
NRZ29_01480	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
NRZ29_01485	COG0222	ribosome binding
NRZ29_01490	COG0085	RNA polymerase activity
NRZ29_01495	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
NRZ29_01500	COG2964	Protein conserved in bacteria
NRZ29_01505	COG0251	oxidation-reduction process
NRZ29_01520	COG2168	tRNA wobble position uridine thiolation
NRZ29_01525	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
NRZ29_01530	COG0049	tRNA binding
NRZ29_01535	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
NRZ29_01540	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
NRZ29_01545	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
NRZ29_01580	COG2252	PERMEase
NRZ29_01585	COG2376	Dihydroxyacetone kinase
NRZ29_01590	COG1461	Dihydroxyacetone kinase
NRZ29_01605	COG3284	Transcriptional regulator
NRZ29_01610	COG2957	Belongs to the agmatine deiminase family
NRZ29_01620	COG0628	permease
NRZ29_01625	COG0494	nUDIX hydrolase
NRZ29_01650	COG0753	catalase activity
NRZ29_01655	COG1247	-acetyltransferase
NRZ29_01675	COG2199	diguanylate cyclase activity
NRZ29_01675	COG2203	Gaf domain
NRZ29_01685	COG3842	ATPase activity
NRZ29_01695	COG1175	transmembrane transport
NRZ29_01720	COG0583	DNA-binding transcription factor activity
NRZ29_01730	COG1741	Belongs to the pirin family
NRZ29_01735	COG2259	Doxx family
NRZ29_01740	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
NRZ29_01745	COG1074	ATP-dependent DNA helicase activity
NRZ29_01750	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
NRZ29_01765	COG0346	lactoylglutathione lyase activity
NRZ29_01810	COG3706	GGDEF domain
NRZ29_01815	COG4771	TonB-dependent receptor
NRZ29_01820	COG1278	Cold shock
NRZ29_01845	COG0629	single-stranded DNA binding
NRZ29_01850	COG2197	response regulator
NRZ29_01855	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
NRZ29_01865	COG3047	cAMP biosynthetic process
NRZ29_01895	COG3135	benzoate transporter
NRZ29_01900	COG1396	sequence-specific DNA binding
NRZ29_01935	COG2926	Belongs to the UPF0265 family
NRZ29_01945	COG3028	Belongs to the UPF0307 family
NRZ29_01950	COG0312	modulator of DNA gyrase
NRZ29_01955	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
NRZ29_01960	COG5007	Belongs to the BolA IbaG family
NRZ29_01970	COG2854	intermembrane phospholipid transfer
NRZ29_01975	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
NRZ29_01980	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
NRZ29_01985	COG1127	ABC transporter
NRZ29_01990	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
NRZ29_01990	COG0517	IMP dehydrogenase activity
NRZ29_01995	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
NRZ29_02000	COG3117	lipopolysaccharide transmembrane transporter activity
NRZ29_02005	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
NRZ29_02010	COG1137	ATPase activity
NRZ29_02015	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
NRZ29_02025	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
NRZ29_02030	COG1660	Displays ATPase and GTPase activities
NRZ29_02035	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
NRZ29_02040	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
NRZ29_02040	COG3711	transcriptional antiterminator
NRZ29_02055	COG3964	amidohydrolase
NRZ29_02085	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
NRZ29_02090	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
NRZ29_02100	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
NRZ29_02105	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
NRZ29_02110	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
NRZ29_02115	COG0723	plastoquinol--plastocyanin reductase activity
NRZ29_02120	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
NRZ29_02125	COG2857	Cytochrome c1
NRZ29_02130	COG0625	glutathione transferase activity
NRZ29_02135	COG2969	positive regulation of protein catabolic process
NRZ29_02140	COG2823	Periplasmic or secreted lipoprotein
NRZ29_02145	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
NRZ29_02150	COG0792	nuclease activity
NRZ29_02155	COG3107	peptidoglycan biosynthetic process
NRZ29_02160	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
NRZ29_02170	COG2001	Belongs to the MraZ family
NRZ29_02175	COG0275	rRNA processing
NRZ29_02180	COG3116	cell division
NRZ29_02185	COG0768	penicillin binding
NRZ29_02190	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
NRZ29_02195	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
NRZ29_02200	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
NRZ29_02205	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
NRZ29_02210	COG0772	Belongs to the SEDS family
NRZ29_02215	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
NRZ29_02220	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
NRZ29_02225	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
NRZ29_02230	COG0849	cell division
NRZ29_02235	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
NRZ29_02240	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
NRZ29_02250	COG0653	protein targeting
NRZ29_02260	COG0494	nUDIX hydrolase
NRZ29_02265	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
NRZ29_02270	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
NRZ29_02285	COG1459	type II secretion system
NRZ29_02290	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
NRZ29_02315	COG2186	Transcriptional regulator
NRZ29_02320	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
NRZ29_02325	COG0508	dehydrogenase complex catalyzes the overall conversion of
NRZ29_02330	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
NRZ29_02340	COG0840	transmembrane signaling receptor activity
NRZ29_02345	COG0840	transmembrane signaling receptor activity
NRZ29_02350	COG1752	Esterase of the alpha-beta hydrolase superfamily
NRZ29_02355	COG1049	propionate catabolic process, 2-methylcitrate cycle
NRZ29_02365	COG1280	lysine exporter protein (LysE YggA)
NRZ29_02375	COG0523	cobalamin synthesis protein
NRZ29_02380	COG0477	Major facilitator Superfamily
NRZ29_02395	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
NRZ29_02400	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
NRZ29_02435	COG3314	Sporulation integral membrane protein YlbJ
NRZ29_02440	COG0835	chemotaxis
NRZ29_02440	COG0784	Response regulator, receiver
NRZ29_02450	COG1444	tRNA N-acetyltransferase activity
NRZ29_02475	COG1803	Methylglyoxal synthase
NRZ29_02490	COG0252	asparaginase activity
NRZ29_02510	COG1263	PTS System
NRZ29_02510	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
NRZ29_02515	COG0366	Alpha amylase catalytic
NRZ29_02520	COG0110	maltose O-acetyltransferase activity
NRZ29_02530	COG1012	belongs to the aldehyde dehydrogenase family
NRZ29_02535	COG1177	transmembrane transport
NRZ29_02540	COG1176	ABC-type spermidine putrescine transport system, permease component I
NRZ29_02545	COG3842	ATPase activity
NRZ29_02550	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
NRZ29_02555	COG0583	DNA-binding transcription factor activity
NRZ29_02560	COG1757	Na H antiporter
NRZ29_02580	COG0297	glycogen (starch) synthase activity
NRZ29_02585	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
NRZ29_02590	COG2813	Specifically methylates the guanine in position
NRZ29_02595	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
NRZ29_02600	COG5001	Diguanylate cyclase
NRZ29_02600	COG4251	negative regulation of phosphorylation
NRZ29_02600	COG3706	GGDEF domain
NRZ29_02600	COG2203	Gaf domain
NRZ29_02610	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
NRZ29_02620	COG2995	paraquat-inducible protein a
NRZ29_02625	COG3008	intermembrane lipid transfer
NRZ29_02625	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
NRZ29_02630	COG3009	Protein conserved in bacteria
NRZ29_02645	COG3240	lipase activity
NRZ29_02650	COG3111	PFAM Bacterial OB fold (BOF) protein
NRZ29_02660	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
NRZ29_02665	COG1194	a g-specific adenine glycosylase
NRZ29_02675	COG3267	Type II secretory pathway component ExeA
NRZ29_02675	COG3409	Peptidoglycan-binding domain 1 protein
NRZ29_02680	COG0617	tRNA 3'-terminal CCA addition
NRZ29_02695	COG1346	cytolysis
NRZ29_02700	COG1380	Effector of murein hydrolase LrgA
NRZ29_02705	COG0583	DNA-binding transcription factor activity
NRZ29_02740	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
NRZ29_02745	COG0306	phosphate transporter
NRZ29_02750	COG1392	Phosphate transport regulator
NRZ29_02765	COG1560	Kdo2-lipid A biosynthetic process
NRZ29_02770	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
NRZ29_02770	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
NRZ29_02775	COG1538	Outer membrane efflux protein
NRZ29_02780	COG0494	nUDIX hydrolase
NRZ29_02785	COG3151	Protein conserved in bacteria
NRZ29_02795	COG3150	esterase
NRZ29_02800	COG1051	belongs to the nudix hydrolase family
NRZ29_02815	COG1566	PFAM secretion protein HlyD family protein
NRZ29_02820	COG1289	transmembrane transporter activity
NRZ29_02840	COG0583	DNA-binding transcription factor activity
NRZ29_02895	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
NRZ29_02915	COG0204	Acyl-transferase
NRZ29_02920	COG1842	Phage shock protein A
NRZ29_02935	COG2827	Endonuclease containing a URI domain
NRZ29_02945	COG2962	Rard protein
NRZ29_02950	COG1573	uracil-dna glycosylase
NRZ29_02955	COG0697	spore germination
NRZ29_02960	COG0583	DNA-binding transcription factor activity
NRZ29_02965	COG1108	ABC-type Mn2 Zn2 transport systems permease components
NRZ29_02970	COG1121	(ABC) transporter
NRZ29_02975	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
NRZ29_02995	COG0739	heme binding
NRZ29_03005	COG3068	Protein conserved in bacteria
NRZ29_03025	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
NRZ29_03030	COG1546	Belongs to the CinA family
NRZ29_03035	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
NRZ29_03045	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
NRZ29_03050	COG0527	aspartate kinase activity
NRZ29_03055	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
NRZ29_03090	COG1686	Belongs to the peptidase S11 family
NRZ29_03095	COG0586	Pfam SNARE associated Golgi protein
NRZ29_03100	COG1253	flavin adenine dinucleotide binding
NRZ29_03110	COG2927	DNA polymerase III (CHI subunit)
NRZ29_03115	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
NRZ29_03120	COG0795	lipopolysaccharide-transporting ATPase activity
NRZ29_03125	COG0795	lipopolysaccharide-transporting ATPase activity
NRZ29_03140	COG0004	ammonium transporteR
NRZ29_03145	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
NRZ29_03155	COG2165	general secretion pathway protein
NRZ29_03160	COG0084	hydrolase, TatD family'
NRZ29_03165	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
NRZ29_03175	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
NRZ29_03180	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
NRZ29_03185	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
NRZ29_03190	COG0813	purine-nucleoside phosphorylase activity
NRZ29_03195	COG3447	MASE1 domain protein
NRZ29_03195	COG5001	Diguanylate cyclase
NRZ29_03195	COG5002	protein histidine kinase activity
NRZ29_03205	COG0560	Phosphoserine phosphatase
NRZ29_03230	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
NRZ29_03240	COG0776	regulation of translation
NRZ29_03255	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
NRZ29_03260	COG0735	belongs to the Fur family
NRZ29_03285	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
NRZ29_03290	COG0513	Belongs to the DEAD box helicase family
NRZ29_03295	COG3022	response to hydroperoxide
NRZ29_03310	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
NRZ29_03315	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
NRZ29_03320	COG0762	integral membrane protein
NRZ29_03325	COG1872	DUF167
NRZ29_03340	COG4166	transmembrane transport
NRZ29_03360	COG1024	Enoyl-CoA hydratase
NRZ29_03375	COG4221	oxidoreductase activity
NRZ29_03380	COG0442	prolyl-tRNA aminoacylation
NRZ29_03385	COG0840	transmembrane signaling receptor activity
NRZ29_03390	COG0632	four-way junction helicase activity
NRZ29_03395	COG2255	four-way junction helicase activity
NRZ29_03400	COG1271	oxidase subunit
NRZ29_03405	COG1294	oxidase, subunit
NRZ29_03410	COG4890	Cyd operon protein YbgT
NRZ29_03415	COG3790	cyd operon protein YbgE
NRZ29_03420	COG0824	Thioesterase
NRZ29_03425	COG0811	peptide transport
NRZ29_03440	COG0823	Involved in the tonB-independent uptake of proteins
NRZ29_03445	COG2885	chlorophyll binding
NRZ29_03450	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
NRZ29_03525	COG0840	transmembrane signaling receptor activity
NRZ29_03530	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
NRZ29_03535	COG0676	glucose-6-phosphate 1-epimerase activity
NRZ29_03540	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
NRZ29_03545	COG1640	4-alpha-glucanotransferase
NRZ29_03550	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
NRZ29_03570	COG1051	belongs to the nudix hydrolase family
NRZ29_03575	COG2130	NADP-dependent
NRZ29_03580	COG1764	response to oxidative stress
NRZ29_03585	COG1846	Transcriptional regulator
NRZ29_03620	COG0561	phosphatase activity
NRZ29_03635	COG0733	neurotransmitter:sodium symporter activity
NRZ29_03645	COG0733	neurotransmitter:sodium symporter activity
NRZ29_03670	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
NRZ29_03685	COG1794	racemase activity, acting on amino acids and derivatives
NRZ29_03690	COG2132	Multicopper oxidase
NRZ29_03695	COG2132	Multicopper oxidase
NRZ29_03705	COG2731	YhcH YjgK YiaL family protein
NRZ29_03715	COG0668	transmembrane transport
NRZ29_03725	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
NRZ29_03735	COG3076	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome
NRZ29_03755	COG0583	DNA-binding transcription factor activity
NRZ29_03760	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
NRZ29_03770	COG0488	(ABC) transporter
NRZ29_03775	COG0517	IMP dehydrogenase activity
NRZ29_03775	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
NRZ29_03780	COG1585	Membrane protein implicated in regulation of membrane protease activity
NRZ29_03785	COG0330	HflC and HflK could
NRZ29_03790	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
NRZ29_03790	COG1648	precorrin-2 dehydrogenase activity
NRZ29_03795	COG0175	sulfate reduction
NRZ29_03800	COG2895	sulfate adenylyltransferase (ATP) activity
NRZ29_03805	COG0471	metal ion transport
NRZ29_03805	COG3273	potassium ion transport
NRZ29_03810	COG0529	Catalyzes the synthesis of activated sulfate
NRZ29_03850	COG0625	glutathione transferase activity
NRZ29_03870	COG1136	(ABC) transporter
NRZ29_03885	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
NRZ29_03900	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
NRZ29_03905	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
NRZ29_03910	COG0163	prenyltransferase activity
NRZ29_03925	COG1131	(ABC) transporter
NRZ29_03930	COG0842	Transport permease protein
NRZ29_03935	COG1775	2-hydroxyglutaryl-CoA dehydratase, D-component
NRZ29_03940	COG1924	4 iron, 4 sulfur cluster binding
NRZ29_03960	COG1823	symporter activity
NRZ29_03965	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
NRZ29_03970	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
NRZ29_03975	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
NRZ29_03985	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
NRZ29_03990	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
NRZ29_03995	COG1489	DNA binding
NRZ29_04005	COG1643	Atp-dependent helicase
NRZ29_04010	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
NRZ29_04015	COG0346	lactoylglutathione lyase activity
NRZ29_04025	COG2076	Multidrug Resistance protein
NRZ29_04035	COG3437	response regulator, receiver
NRZ29_04035	COG0784	Response regulator, receiver
NRZ29_04045	COG0671	phosphoesterase, PA-phosphatase related
NRZ29_04060	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
NRZ29_04065	COG0038	chloride channel
NRZ29_04075	COG0316	Belongs to the HesB IscA family
NRZ29_04115	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
NRZ29_04120	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
NRZ29_04125	COG1178	ABC-type Fe3 transport system permease component
NRZ29_04130	COG4143	(ABC) transporter
NRZ29_04145	COG0066	3-isopropylmalate dehydratase activity
NRZ29_04150	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
NRZ29_04155	COG0473	3-isopropylmalate dehydrogenase activity
NRZ29_04160	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
NRZ29_04170	COG0671	phosphoesterase, PA-phosphatase related
NRZ29_04175	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
NRZ29_04185	COG0028	Belongs to the TPP enzyme family
NRZ29_04195	COG0280	phosphate acetyltransferase
NRZ29_04195	COG0857	belongs to the CobB CobQ family
NRZ29_04200	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
NRZ29_04210	COG3013	Belongs to the UPF0304 family
NRZ29_04215	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
NRZ29_04220	COG2716	regulation of RNA biosynthetic process
NRZ29_04230	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
NRZ29_04235	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
NRZ29_04250	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
NRZ29_04270	COG2198	Histidine kinase
NRZ29_04270	COG5002	protein histidine kinase activity
NRZ29_04270	COG0784	Response regulator, receiver
NRZ29_04295	COG0840	transmembrane signaling receptor activity
NRZ29_04315	COG1464	Belongs to the NlpA lipoprotein family
NRZ29_04320	COG2011	ABC-type metal ion transport system permease component
NRZ29_04325	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
NRZ29_04340	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
NRZ29_04345	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
NRZ29_04345	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
NRZ29_04350	COG0802	atpase or kinase
NRZ29_04360	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
NRZ29_04365	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
NRZ29_04370	COG1923	regulation of RNA biosynthetic process
NRZ29_04375	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
NRZ29_04380	COG0330	HflC and HflK could
NRZ29_04385	COG0330	HflC and HflK could
NRZ29_04390	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
NRZ29_04395	COG0142	geranyltranstransferase activity
NRZ29_04400	COG0261	This protein binds to 23S rRNA in the presence of protein L20
NRZ29_04405	COG0211	Belongs to the bacterial ribosomal protein bL27 family
NRZ29_04410	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
NRZ29_04415	COG3314	Sporulation integral membrane protein YlbJ
NRZ29_04420	COG0318	PFAM AMP-dependent synthetase and ligase
NRZ29_04435	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
NRZ29_04440	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NRZ29_04450	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
NRZ29_04455	COG2967	ApaG domain
NRZ29_04460	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
NRZ29_04465	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
NRZ29_04475	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
NRZ29_04480	COG3178	'Phosphotransferase
NRZ29_04485	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
NRZ29_04490	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
NRZ29_04495	COG2252	PERMEase
NRZ29_04505	COG0488	(ABC) transporter
NRZ29_04520	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
NRZ29_04525	COG0741	lytic transglycosylase activity
NRZ29_04545	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
NRZ29_04550	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
NRZ29_04555	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
NRZ29_04580	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NRZ29_04590	COG3721	Heme iron utilization protein
NRZ29_04595	COG0748	coenzyme F420 binding
NRZ29_04615	COG4771	TonB-dependent receptor
NRZ29_04620	COG2814	Major facilitator Superfamily
NRZ29_04625	COG3655	Transcriptional regulator
NRZ29_04635	COG2205	protein histidine kinase activity
NRZ29_04635	COG2202	Pas domain
NRZ29_04650	COG3397	chitin binding
NRZ29_04655	COG2226	methyltransferase
NRZ29_04665	COG1765	OsmC-like protein
NRZ29_04680	COG3954	Phosphoribulokinase
NRZ29_04685	COG2076	Multidrug Resistance protein
NRZ29_04690	COG2076	Multidrug Resistance protein
NRZ29_04695	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
NRZ29_04700	COG0726	polysaccharide deacetylase
NRZ29_04705	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
NRZ29_04705	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
NRZ29_04710	COG0463	Glycosyl transferase, family 2
NRZ29_04715	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
NRZ29_04725	COG3089	Belongs to the UPF0270 family
NRZ29_04730	COG5001	Diguanylate cyclase
NRZ29_04730	COG4251	negative regulation of phosphorylation
NRZ29_04730	COG3706	GGDEF domain
NRZ29_04730	COG2203	Gaf domain
NRZ29_04735	COG0429	hydrolase of the alpha beta-hydrolase fold
NRZ29_04740	COG0835	chemotaxis
NRZ29_04740	COG0784	Response regulator, receiver
NRZ29_04750	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
NRZ29_04755	COG1047	Peptidyl-prolyl cis-trans
NRZ29_04770	COG0545	Peptidyl-prolyl cis-trans isomerase
NRZ29_04775	COG2204	response regulator
NRZ29_04795	COG0737	Belongs to the 5'-nucleotidase family
NRZ29_04800	COG2200	EAL domain
NRZ29_04815	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
NRZ29_04825	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
NRZ29_04830	COG0826	peptidase U32
NRZ29_04835	COG2203	Gaf domain
NRZ29_04835	COG2200	EAL domain
NRZ29_04835	COG2199	diguanylate cyclase activity
NRZ29_04860	COG2197	response regulator
NRZ29_04865	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
NRZ29_04865	COG2205	protein histidine kinase activity
NRZ29_04890	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
NRZ29_04895	COG2201	protein-glutamate methylesterase activity
NRZ29_04900	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
NRZ29_04910	COG0840	transmembrane signaling receptor activity
NRZ29_04915	COG0835	chemotaxis
NRZ29_04925	COG0643	Histidine kinase
NRZ29_04925	COG2198	Histidine kinase
NRZ29_04940	COG0840	transmembrane signaling receptor activity
NRZ29_04945	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
NRZ29_04955	COG1280	lysine exporter protein (LysE YggA)
NRZ29_04960	COG0826	peptidase U32
NRZ29_04990	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
NRZ29_05015	COG0300	oxidoreductase activity
NRZ29_05025	COG0840	transmembrane signaling receptor activity
NRZ29_05035	COG2610	gluconate transmembrane transporter activity
NRZ29_05040	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
NRZ29_05045	COG3622	Belongs to the hyi family
NRZ29_05050	COG0235	Class ii aldolase
NRZ29_05060	COG2084	Dehydrogenase
NRZ29_05065	COG1349	DNA-binding transcription factor activity
NRZ29_05095	COG1204	response to ionizing radiation
NRZ29_05145	COG5377	YqaJ viral recombinase family
NRZ29_05175	COG1605	Chorismate mutase
NRZ29_05175	COG0077	Prephenate dehydratase
NRZ29_05205	COG3272	Protein of unknown function (DUF1722)
NRZ29_05210	COG0789	Transcriptional regulator
NRZ29_05215	COG0415	Belongs to the DNA photolyase family
NRZ29_05225	COG4221	oxidoreductase activity
NRZ29_05240	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
NRZ29_05265	COG0783	Belongs to the Dps family
NRZ29_05270	COG1151	hydroxylamine reductase activity
NRZ29_05280	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
NRZ29_05285	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
NRZ29_05285	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
NRZ29_05295	COG2771	luxR family
NRZ29_05345	COG0693	protein deglycase activity
NRZ29_05350	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
NRZ29_05355	COG1666	GTP binding
NRZ29_05360	COG3248	Nucleoside-binding outer membrane protein
NRZ29_05365	COG2211	Major facilitator Superfamily
NRZ29_05375	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
NRZ29_05385	COG2813	Specifically methylates the guanine in position
NRZ29_05390	COG0271	Belongs to the BolA IbaG family
NRZ29_05395	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
NRZ29_05400	COG1805	sodium ion transport
NRZ29_05405	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
NRZ29_05410	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
NRZ29_05415	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
NRZ29_05420	COG2871	sodium ion transport
NRZ29_05425	COG1477	protein flavinylation
NRZ29_05440	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
NRZ29_05445	COG0840	transmembrane signaling receptor activity
NRZ29_05450	COG0583	DNA-binding transcription factor activity
NRZ29_05460	COG2363	Small membrane protein
NRZ29_05465	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
NRZ29_05475	COG0473	3-isopropylmalate dehydrogenase activity
NRZ29_05480	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
NRZ29_05485	COG1611	Belongs to the LOG family
NRZ29_05500	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
NRZ29_05500	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
NRZ29_05510	COG5595	Zn-ribbon-containing, possibly nucleic-acid-binding protein (DUF2310)
NRZ29_05535	COG3098	single-species biofilm formation
NRZ29_05540	COG0564	pseudouridine synthase activity
NRZ29_05550	COG4580	involved in the transport of maltose and maltodextrins
NRZ29_05560	COG1263	PTS System
NRZ29_05560	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
NRZ29_05570	COG2171	N-acyltransferase activity
NRZ29_05575	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
NRZ29_05580	COG0024	Methionine aminopeptidase
NRZ29_05585	COG0052	Belongs to the universal ribosomal protein uS2 family
NRZ29_05590	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
NRZ29_05595	COG0528	UMP kinase activity
NRZ29_05600	COG0233	cytoplasmic translational termination
NRZ29_05605	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
NRZ29_05610	COG0575	Belongs to the CDS family
NRZ29_05615	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
NRZ29_05620	COG0750	zinc metalloprotease
NRZ29_05635	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
NRZ29_05640	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
NRZ29_05645	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
NRZ29_05650	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
NRZ29_05655	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
NRZ29_05665	COG0825	malonyl-CoA metabolic process
NRZ29_05670	COG3710	Transcriptional regulator
NRZ29_05675	COG0531	amino acid
NRZ29_05680	COG1982	Orn Lys Arg decarboxylase major
NRZ29_05685	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
NRZ29_05700	COG0814	amino acid
NRZ29_05705	COG0531	amino acid
NRZ29_05715	COG0488	(ABC) transporter
NRZ29_05725	COG3590	peptidase
NRZ29_05735	COG3706	GGDEF domain
NRZ29_05775	COG0366	Alpha amylase catalytic
NRZ29_05790	COG0463	Glycosyl transferase, family 2
NRZ29_05805	COG2989	Protein conserved in bacteria
NRZ29_05810	COG3108	Peptidase M15
NRZ29_05820	COG2860	membrane
NRZ29_05830	COG1196	nuclear chromosome segregation
NRZ29_05835	COG3115	cell septum assembly
NRZ29_05840	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
NRZ29_05850	COG1328	CTP reductase activity
NRZ29_05855	COG0602	queuosine metabolic process
NRZ29_05885	COG1566	PFAM secretion protein HlyD family protein
NRZ29_05890	COG1846	Transcriptional regulator
NRZ29_05905	COG0281	malic enzyme
NRZ29_05910	COG3290	protein histidine kinase activity
NRZ29_05915	COG4565	transcriptional regulatory protein
NRZ29_05920	COG0697	spore germination
NRZ29_05935	COG3284	Transcriptional regulator
NRZ29_05940	COG1960	acyl-CoA dehydrogenase activity
NRZ29_05945	COG1804	L-carnitine dehydratase bile acid-inducible protein F
NRZ29_05950	COG0346	lactoylglutathione lyase activity
NRZ29_05955	COG0745	RESPONSE REGULATOR receiver
NRZ29_05960	COG5002	protein histidine kinase activity
NRZ29_05985	COG3142	Participates in the control of copper homeostasis
NRZ29_05995	COG0545	Peptidyl-prolyl cis-trans isomerase
NRZ29_06000	COG1131	(ABC) transporter
NRZ29_06020	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
NRZ29_06030	COG0678	peroxiredoxin activity
NRZ29_06040	COG0019	diaminopimelate decarboxylase activity
NRZ29_06045	COG1115	amino acid carrier protein
NRZ29_06050	COG0095	Lipoate-protein ligase
NRZ29_06055	COG2233	PERMEase
NRZ29_06070	COG0534	Mate efflux family protein
NRZ29_06080	COG0281	malic enzyme
NRZ29_06110	COG0733	neurotransmitter:sodium symporter activity
NRZ29_06115	COG1752	Esterase of the alpha-beta hydrolase superfamily
NRZ29_06125	COG1566	PFAM secretion protein HlyD family protein
NRZ29_06130	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
NRZ29_06140	COG1032	radical SAM domain protein
NRZ29_06170	COG0673	inositol 2-dehydrogenase activity
NRZ29_06175	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
NRZ29_06180	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
NRZ29_06185	COG0739	heme binding
NRZ29_06185	COG0741	lytic transglycosylase activity
NRZ29_06185	COG1196	nuclear chromosome segregation
NRZ29_06190	COG0366	Alpha amylase catalytic
NRZ29_06210	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
NRZ29_06220	COG0788	formyltetrahydrofolate deformylase activity
NRZ29_06225	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
NRZ29_06235	COG3118	belongs to the thioredoxin family
NRZ29_06240	COG2091	lysine biosynthetic process via aminoadipic acid
NRZ29_06245	COG0791	NLP P60 protein
NRZ29_06250	COG3129	Specifically methylates the adenine in position 1618 of 23S rRNA
NRZ29_06265	COG1376	ErfK ybiS ycfS ynhG family protein
NRZ29_06265	COG1388	LysM domain
NRZ29_06320	COG4869	propanediol catabolic process
NRZ29_06330	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
NRZ29_06335	COG1882	Formate acetyltransferase
NRZ29_06340	COG1012	belongs to the aldehyde dehydrogenase family
NRZ29_06340	COG1454	alcohol dehydrogenase
NRZ29_06350	COG1454	alcohol dehydrogenase
NRZ29_06350	COG1012	belongs to the aldehyde dehydrogenase family
NRZ29_06385	COG0583	DNA-binding transcription factor activity
NRZ29_06390	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
NRZ29_06395	COG0243	molybdopterin cofactor binding
NRZ29_06405	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
NRZ29_06415	COG1960	acyl-CoA dehydrogenase activity
NRZ29_06430	COG0469	pyruvate kinase activity
NRZ29_06435	COG1737	Transcriptional regulator
NRZ29_06455	COG2274	protein secretion by the type I secretion system
NRZ29_06465	COG2274	protein secretion by the type I secretion system
NRZ29_06475	COG2994	toxin metabolic process
NRZ29_06480	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
NRZ29_06480	COG3064	Membrane
NRZ29_06480	COG1073	alpha beta
NRZ29_06490	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
NRZ29_06505	COG1677	Flagellar hook-basal body complex protein FliE
NRZ29_06515	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
NRZ29_06570	COG1684	flagellar biosynthetic protein fliR
NRZ29_06580	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
NRZ29_06605	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
NRZ29_06610	COG0643	Histidine kinase
NRZ29_06610	COG0784	Response regulator, receiver
NRZ29_06610	COG2198	Histidine kinase
NRZ29_06615	COG2201	protein-glutamate methylesterase activity
NRZ29_06620	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
NRZ29_06625	COG1360	Flagellar Motor Protein
NRZ29_06630	COG1192	Involved in chromosome partitioning
NRZ29_06640	COG0835	chemotaxis
NRZ29_06655	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
NRZ29_06660	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
NRZ29_06665	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
NRZ29_06670	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
NRZ29_06675	COG1138	Cytochrome C-type biogenesis protein
NRZ29_06680	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
NRZ29_06685	COG3088	subunit of a heme lyase
NRZ29_06685	COG4235	cytochrome complex assembly
NRZ29_06690	COG3088	subunit of a heme lyase
NRZ29_06690	COG4235	cytochrome complex assembly
NRZ29_06705	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
NRZ29_06710	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
NRZ29_06710	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
NRZ29_06725	COG0259	pyridoxamine-phosphate oxidase activity
NRZ29_06730	COG0625	glutathione transferase activity
NRZ29_06740	COG3153	acetyltransferase
NRZ29_06745	COG2850	peptidyl-arginine hydroxylation
NRZ29_06755	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
NRZ29_06760	COG2915	High frequency lysogenization protein hflD homolog
NRZ29_06765	COG0482	sulfurtransferase activity
NRZ29_06775	COG1187	pseudouridine synthase activity
NRZ29_06785	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
NRZ29_06795	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
NRZ29_06795	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
NRZ29_06795	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
NRZ29_06815	COG0456	acetyltransferase
NRZ29_06825	COG1609	Transcriptional regulator
NRZ29_06830	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
NRZ29_06830	COG1263	PTS System
NRZ29_06835	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
NRZ29_06850	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
NRZ29_06870	COG2207	Transcriptional regulator
NRZ29_06875	COG0538	isocitrate dehydrogenase activity
NRZ29_06885	COG3048	D-serine ammonia-lyase activity
NRZ29_06890	COG2610	gluconate transmembrane transporter activity
NRZ29_06895	COG0583	DNA-binding transcription factor activity
NRZ29_06915	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
NRZ29_06920	COG2867	negative regulation of translational initiation
NRZ29_06925	COG2914	Belongs to the UPF0125 (RnfH) family
NRZ29_06930	COG0702	epimerase
NRZ29_06935	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
NRZ29_06965	COG4964	Belongs to the GSP D family
NRZ29_07015	COG1454	alcohol dehydrogenase
NRZ29_07025	COG0564	pseudouridine synthase activity
NRZ29_07055	COG1280	lysine exporter protein (LysE YggA)
NRZ29_07075	COG3263	regulation of cellular component size
NRZ29_07085	COG1876	peptidase activity
NRZ29_07090	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
NRZ29_07095	COG1393	Belongs to the ArsC family
NRZ29_07100	COG0583	DNA-binding transcription factor activity
NRZ29_07110	COG3069	C4-dicarboxylate transmembrane transporter activity
NRZ29_07115	COG1473	amidohydrolase
NRZ29_07125	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
NRZ29_07130	COG0017	Asparaginyl-tRNA synthetase
NRZ29_07150	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
NRZ29_07155	COG0156	8-amino-7-oxononanoate synthase activity
NRZ29_07160	COG1073	alpha beta
NRZ29_07160	COG2226	methyltransferase
NRZ29_07165	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
NRZ29_07170	COG0501	Belongs to the peptidase M48B family
NRZ29_07180	COG3217	Mosc domain protein beta barrel domain protein
NRZ29_07180	COG0633	Ferredoxin
NRZ29_07180	COG0633	Ferredoxin
NRZ29_07180	COG3217	Mosc domain protein beta barrel domain protein
NRZ29_07190	COG0674	pyruvate-flavodoxin oxidoreductase activity
NRZ29_07190	COG1013	pyruvate-flavodoxin oxidoreductase activity
NRZ29_07190	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
NRZ29_07190	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
NRZ29_07195	COG2366	antibiotic biosynthetic process
NRZ29_07215	COG0534	Mate efflux family protein
NRZ29_07255	COG1309	transcriptional regulator
NRZ29_07270	COG0791	NLP P60 protein
NRZ29_07280	COG0583	DNA-binding transcription factor activity
NRZ29_07285	COG0450	alkyl hydroperoxide reductase
NRZ29_07305	COG0500	methyltransferase
NRZ29_07310	COG4106	trans-aconitate 2-methyltransferase activity
NRZ29_07315	COG1801	Protein of unknown function DUF72
NRZ29_07320	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
NRZ29_07325	COG0217	transcriptional regulatory protein
NRZ29_07330	COG2194	sulfuric ester hydrolase activity
NRZ29_07340	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
NRZ29_07345	COG2244	polysaccharide biosynthetic process
NRZ29_07355	COG1215	transferase activity, transferring glycosyl groups
NRZ29_07390	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
NRZ29_07395	COG0489	protein tyrosine kinase activity
NRZ29_07395	COG3206	protein involved in exopolysaccharide biosynthesis
NRZ29_07415	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
NRZ29_07425	COG3132	Protein of unknown function, DUF480
NRZ29_07465	COG1278	Cold shock
NRZ29_07500	COG1349	DNA-binding transcription factor activity
NRZ29_07505	COG1882	Formate acetyltransferase
NRZ29_07510	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
NRZ29_07515	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
NRZ29_07545	COG0622	Phosphoesterase
NRZ29_07560	COG1261	Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly
NRZ29_07565	COG0784	Response regulator, receiver
NRZ29_07565	COG0835	chemotaxis
NRZ29_07570	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
NRZ29_07575	COG1815	bacterial-type flagellum-dependent cell motility
NRZ29_07595	COG4787	bacterial-type flagellum-dependent cell motility
NRZ29_07605	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
NRZ29_07610	COG1706	bacterial-type flagellum-dependent cell motility
NRZ29_07615	COG1705	Flagellar rod assembly protein muramidase FlgJ
NRZ29_07615	COG3951	Flagellar rod assembly protein muramidase FlgJ
NRZ29_07620	COG1256	bacterial-type flagellum assembly
NRZ29_07630	COG2239	Acts as a magnesium transporter
NRZ29_07640	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
NRZ29_07645	COG2716	regulation of RNA biosynthetic process
NRZ29_07670	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
NRZ29_07675	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
NRZ29_07680	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
NRZ29_07685	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
NRZ29_07705	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
NRZ29_07720	COG0590	tRNA wobble adenosine to inosine editing
NRZ29_07725	COG0573	inorganic phosphate transmembrane transporter activity
NRZ29_07730	COG0581	inorganic phosphate transmembrane transporter activity
NRZ29_07735	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
NRZ29_07740	COG0704	Plays a role in the regulation of phosphate uptake
NRZ29_07745	COG1253	flavin adenine dinucleotide binding
NRZ29_07760	COG0531	amino acid
NRZ29_07785	COG0765	amino acid transport
NRZ29_07790	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
NRZ29_07800	COG2271	Major facilitator Superfamily
NRZ29_07815	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
NRZ29_07840	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
NRZ29_07845	COG0477	Major facilitator Superfamily
NRZ29_07850	COG0123	including yeast histone deacetylase and acetoin utilization protein
NRZ29_07860	COG1199	ATP-dependent helicase activity
NRZ29_07875	COG1448	Aminotransferase
NRZ29_07880	COG0433	COG0433 Predicted ATPase
NRZ29_07895	COG0658	competence protein
NRZ29_07895	COG2333	competence protein COMEC
NRZ29_07905	COG1663	tetraacyldisaccharide 4'-kinase activity
NRZ29_07910	COG2835	tetraacyldisaccharide 4'-kinase activity
NRZ29_07915	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
NRZ29_07920	COG2197	response regulator
NRZ29_07925	COG0322	excinuclease ABC activity
NRZ29_08030	COG3646	Phage regulatory protein
NRZ29_08115	COG4695	Portal protein
NRZ29_08145	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
NRZ29_08240	COG4974	Belongs to the 'phage' integrase family
NRZ29_08295	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
NRZ29_08300	COG0437	4 iron, 4 sulfur cluster binding
NRZ29_08305	COG3301	Polysulphide reductase, NrfD
NRZ29_08310	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
NRZ29_08320	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
NRZ29_08345	COG2203	Gaf domain
NRZ29_08345	COG2199	diguanylate cyclase activity
NRZ29_08375	COG2119	membrane
NRZ29_08380	COG0023	Translation Initiation Factor
NRZ29_08405	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
NRZ29_08420	COG2205	protein histidine kinase activity
NRZ29_08420	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
NRZ29_08430	COG4138	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system
NRZ29_08440	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
NRZ29_08445	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
NRZ29_08450	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
NRZ29_08455	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
NRZ29_08460	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
NRZ29_08470	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
NRZ29_08475	COG0505	Belongs to the CarA family
NRZ29_08480	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
NRZ29_08485	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
NRZ29_08525	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
NRZ29_08530	COG0513	Belongs to the DEAD box helicase family
NRZ29_08540	COG4104	PAAR repeat-containing protein
NRZ29_08555	COG0789	Transcriptional regulator
NRZ29_08570	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
NRZ29_08575	COG0765	amino acid transport
NRZ29_08580	COG1126	abc transporter atp-binding protein
NRZ29_08585	COG0493	'glutamate synthase
NRZ29_08590	COG0067	glutamate synthase
NRZ29_08590	COG0069	glutamate synthase activity
NRZ29_08590	COG0070	glutamate synthase
NRZ29_08595	COG1242	4 iron, 4 sulfur cluster binding
NRZ29_08655	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
NRZ29_08660	COG0574	Belongs to the PEP-utilizing enzyme family
NRZ29_08660	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
NRZ29_08690	COG1464	Belongs to the NlpA lipoprotein family
NRZ29_08695	COG0671	phosphoesterase, PA-phosphatase related
NRZ29_08700	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
NRZ29_08705	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
NRZ29_08715	COG0101	tRNA pseudouridine synthase activity
NRZ29_08720	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
NRZ29_08725	COG0285	dihydrofolate synthase activity
NRZ29_08730	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
NRZ29_08735	COG2920	part of a sulfur-relay system
NRZ29_08740	COG1289	transmembrane transporter activity
NRZ29_08745	COG0670	Belongs to the BI1 family
NRZ29_08760	COG2194	sulfuric ester hydrolase activity
NRZ29_08765	COG0392	lysyltransferase activity
NRZ29_08765	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
NRZ29_08775	COG0840	transmembrane signaling receptor activity
NRZ29_08780	COG5001	Diguanylate cyclase
NRZ29_08785	COG0564	pseudouridine synthase activity
NRZ29_08800	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
NRZ29_08810	COG0625	glutathione transferase activity
NRZ29_08820	COG0367	asparagine synthase
NRZ29_08830	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
NRZ29_08830	COG4651	solute:proton antiporter activity
NRZ29_08835	COG0647	UMP catabolic process
NRZ29_08845	COG1902	pentaerythritol trinitrate reductase activity
NRZ29_08850	COG1253	flavin adenine dinucleotide binding
NRZ29_08860	COG0277	FAD linked oxidase domain protein
NRZ29_08860	COG0247	lactate metabolic process
NRZ29_08870	COG2050	protein possibly involved in aromatic compounds catabolism
NRZ29_08880	COG2056	Na+-H+ antiporter family
NRZ29_08885	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
NRZ29_08900	COG0346	lactoylglutathione lyase activity
NRZ29_08905	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
NRZ29_08910	COG4660	Part of a membrane complex involved in electron transport
NRZ29_08915	COG4659	FMN binding
NRZ29_08920	COG4658	electron transport chain
NRZ29_08930	COG2878	Part of a membrane complex involved in electron transport
NRZ29_08935	COG4657	Part of a membrane complex involved in electron transport
NRZ29_08940	COG0697	spore germination
NRZ29_08960	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
NRZ29_08965	COG1288	antiporter activity
NRZ29_08970	COG0436	Aminotransferase
NRZ29_08980	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
NRZ29_08985	COG2027	D-alanyl-D-alanine carboxypeptidase
NRZ29_08990	COG1061	Type III restriction enzyme res subunit
NRZ29_08995	COG1566	PFAM secretion protein HlyD family protein
NRZ29_09005	COG1966	Carbon starvation protein
NRZ29_09010	COG3279	Response regulator of the LytR AlgR family
NRZ29_09015	COG3275	phosphorelay sensor kinase activity
NRZ29_09020	COG2199	diguanylate cyclase activity
NRZ29_09020	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
NRZ29_09025	COG1454	alcohol dehydrogenase
NRZ29_09025	COG1012	belongs to the aldehyde dehydrogenase family
NRZ29_09035	COG2095	MarC family integral membrane protein
NRZ29_09045	COG0601	transmembrane transport
NRZ29_09050	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
NRZ29_09065	COG0861	Integral membrane protein TerC family
NRZ29_09070	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
NRZ29_09080	COG1301	dicarboxylic acid transport
NRZ29_09095	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
NRZ29_09110	COG0537	adenosine 5'-monophosphoramidase activity
NRZ29_09145	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
NRZ29_09150	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
NRZ29_09160	COG2354	Protein conserved in bacteria
NRZ29_09175	COG2233	PERMEase
NRZ29_09180	COG3150	esterase
NRZ29_09185	COG1252	NADH dehydrogenase
NRZ29_09205	COG0393	Putative heavy-metal-binding
NRZ29_09215	COG4667	esterase of the alpha-beta hydrolase superfamily
NRZ29_09220	COG1619	proteins homologs of microcin C7 resistance protein MccF
NRZ29_09225	COG1368	sulfuric ester hydrolase activity
NRZ29_09235	COG0527	aspartate kinase activity
NRZ29_09240	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
NRZ29_09240	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
NRZ29_09245	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
NRZ29_09265	COG0596	Alpha beta hydrolase
NRZ29_09270	COG0346	lactoylglutathione lyase activity
NRZ29_09280	COG0583	DNA-binding transcription factor activity
NRZ29_09285	COG1620	l-lactate permease
NRZ29_09295	COG1139	Iron-sulfur cluster binding protein
NRZ29_09330	COG0577	efflux transmembrane transporter activity
NRZ29_09335	COG1136	(ABC) transporter
NRZ29_09345	COG2814	Major facilitator Superfamily
NRZ29_09365	COG0672	)-iron permease
NRZ29_09395	COG0659	secondary active sulfate transmembrane transporter activity
NRZ29_09415	COG0840	transmembrane signaling receptor activity
NRZ29_09425	COG2201	protein-glutamate methylesterase activity
NRZ29_09435	COG0835	chemotaxis
NRZ29_09440	COG0840	transmembrane signaling receptor activity
NRZ29_09440	COG3290	protein histidine kinase activity
NRZ29_09445	COG2198	Histidine kinase
NRZ29_09445	COG0643	Histidine kinase
NRZ29_09455	COG0745	RESPONSE REGULATOR receiver
NRZ29_09460	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
NRZ29_09465	COG0437	4 iron, 4 sulfur cluster binding
NRZ29_09470	COG5557	Pfam Polysulphide reductase, NrfD
NRZ29_09475	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
NRZ29_09480	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
NRZ29_09485	COG1773	rubredoxin
NRZ29_09500	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
NRZ29_09505	COG0444	Belongs to the ABC transporter superfamily
NRZ29_09510	COG1124	(ABC) transporter
NRZ29_09515	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
NRZ29_09525	COG0375	protein maturation
NRZ29_09530	COG0309	Hydrogenase expression formation protein (HypE)
NRZ29_09540	COG0298	carbon dioxide binding
NRZ29_09545	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
NRZ29_09555	COG1921	L-seryl-tRNASec selenium transferase activity
NRZ29_09565	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
NRZ29_09575	COG3260	NADH ubiquinone oxidoreductase 20
NRZ29_09580	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
NRZ29_09585	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
NRZ29_09585	COG3261	NADH dehydrogenase
NRZ29_09590	COG0650	Formate hydrogenlyase subunit 4
NRZ29_09595	COG0651	ATP synthesis coupled electron transport
NRZ29_09600	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
NRZ29_09605	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
NRZ29_09615	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
NRZ29_09620	COG2223	nitrite transmembrane transporter activity
NRZ29_09630	COG3158	transport of potassium into the cell
NRZ29_09635	COG0232	Belongs to the dGTPase family. Type 2 subfamily
NRZ29_09650	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
NRZ29_09675	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
NRZ29_09680	COG0326	Molecular chaperone. Has ATPase activity
NRZ29_09685	COG0563	adenylate kinase activity
NRZ29_09690	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
NRZ29_09695	COG3788	relative of glutathione S-transferase, MAPEG superfamily
NRZ29_09700	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
NRZ29_09715	COG3300	MHYT domain
NRZ29_09715	COG5001	Diguanylate cyclase
NRZ29_09720	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
NRZ29_09740	COG1021	2,3-dihydroxybenzoate-AMP ligase
NRZ29_09745	COG1535	isochorismatase
NRZ29_09745	COG3433	isochorismatase activity
NRZ29_09750	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
NRZ29_09755	COG1028	Short-chain dehydrogenase reductase Sdr
NRZ29_09765	COG0318	PFAM AMP-dependent synthetase and ligase
NRZ29_09765	COG0300	oxidoreductase activity
NRZ29_09765	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
NRZ29_09765	COG1028	Short-chain dehydrogenase reductase Sdr
NRZ29_09765	COG3321	synthase
NRZ29_09775	COG1051	belongs to the nudix hydrolase family
NRZ29_09780	COG3088	subunit of a heme lyase
NRZ29_09780	COG4235	cytochrome complex assembly
NRZ29_09785	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
NRZ29_09790	COG1138	Cytochrome C-type biogenesis protein
NRZ29_09795	COG3301	Polysulphide reductase, NrfD
NRZ29_09800	COG0437	4 iron, 4 sulfur cluster binding
NRZ29_09805	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
NRZ29_09815	COG0247	lactate metabolic process
NRZ29_09820	COG3075	Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses fumarate or nitrate as electron acceptor
NRZ29_09825	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
NRZ29_09830	COG3012	SEC-C Motif Domain Protein
NRZ29_09835	COG0840	transmembrane signaling receptor activity
NRZ29_09840	COG1846	Transcriptional regulator
NRZ29_09840	COG1940	carbohydrate kinase activity
NRZ29_09845	COG3290	protein histidine kinase activity
NRZ29_09850	COG4565	transcriptional regulatory protein
NRZ29_09870	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
NRZ29_09875	COG2985	domain, Protein
NRZ29_09875	COG0569	domain protein
NRZ29_09885	COG0556	nucleotide-excision repair
NRZ29_09895	COG0586	Pfam SNARE associated Golgi protein
NRZ29_09900	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
NRZ29_09905	COG3067	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
NRZ29_09910	COG2186	Transcriptional regulator
NRZ29_09915	COG2719	SpoVR family
NRZ29_09925	COG2766	serine protein kinase
NRZ29_09930	COG0514	ATP-dependent DNA helicase (RecQ)
NRZ29_09935	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
NRZ29_09940	COG0814	amino acid
NRZ29_09970	COG0058	SHG alpha-glucan phosphorylase activity
NRZ29_09975	COG0471	metal ion transport
NRZ29_09980	COG3118	belongs to the thioredoxin family
NRZ29_09990	COG1132	(ABC) transporter
NRZ29_09995	COG1132	(ABC) transporter
NRZ29_10010	COG2501	S4 domain
NRZ29_10020	COG3243	poly(R)-hydroxyalkanoic acid synthase
NRZ29_10040	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
NRZ29_10045	COG2329	Antibiotic biosynthesis monooxygenase
NRZ29_10075	COG1742	UPF0060 membrane protein
NRZ29_10085	COG0456	acetyltransferase
NRZ29_10090	COG0513	Belongs to the DEAD box helicase family
NRZ29_10095	COG0386	Belongs to the glutathione peroxidase family
NRZ29_10105	COG1181	Belongs to the D-alanine--D-alanine ligase family
NRZ29_10115	COG3148	PFAM DTW domain containing protein
NRZ29_10120	COG0730	response to heat
NRZ29_10125	COG0583	DNA-binding transcription factor activity
NRZ29_10145	COG3593	DNA synthesis involved in DNA repair
NRZ29_10200	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
NRZ29_10205	COG1011	Hydrolase
NRZ29_10210	COG1473	amidohydrolase
NRZ29_10215	COG0205	6-phosphofructokinase activity
NRZ29_10225	COG1434	Gram-negative-bacterium-type cell wall biogenesis
NRZ29_10230	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
NRZ29_10240	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
NRZ29_10245	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
NRZ29_10250	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
NRZ29_10260	COG0242	peptide deformylase activity
NRZ29_10290	COG0384	phenazine biosynthesis protein PhzF
NRZ29_10300	COG2824	Alkylphosphonate utilization operon protein PhnA
NRZ29_10310	COG0740	serine-type endopeptidase activity
NRZ29_10340	COG3706	GGDEF domain
NRZ29_10350	COG2840	Smr protein MutS2
NRZ29_10355	COG2890	protein-(glutamine-N5) methyltransferase activity
NRZ29_10360	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
NRZ29_10370	COG0513	Belongs to the DEAD box helicase family
NRZ29_10375	COG5654	RES domain protein
NRZ29_10385	COG0814	amino acid
NRZ29_10390	COG1609	Transcriptional regulator
NRZ29_10395	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
NRZ29_10395	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
NRZ29_10400	COG1105	Belongs to the carbohydrate kinase PfkB family
NRZ29_10405	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
NRZ29_10405	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
NRZ29_10405	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
NRZ29_10410	COG2140	Oxalate decarboxylase
NRZ29_10415	COG1609	Transcriptional regulator
NRZ29_10430	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
NRZ29_10430	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
NRZ29_10435	COG3715	PTS system
NRZ29_10440	COG3716	PTS system mannose fructose sorbose family IID component
NRZ29_10450	COG3313	Fe-S protein
NRZ29_10455	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
NRZ29_10460	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
NRZ29_10465	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NRZ29_10470	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NRZ29_10480	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
NRZ29_10505	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
NRZ29_10510	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
NRZ29_10515	COG0291	Belongs to the bacterial ribosomal protein bL35 family
NRZ29_10520	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
NRZ29_10525	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
NRZ29_10530	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NRZ29_10530	COG0072	phenylalanine-tRNA ligase activity
NRZ29_10535	COG0776	regulation of translation
NRZ29_10565	COG3300	MHYT domain
NRZ29_10565	COG5001	Diguanylate cyclase
NRZ29_10570	COG1609	Transcriptional regulator
NRZ29_10575	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
NRZ29_10580	COG1879	ABC-type sugar transport system periplasmic component
NRZ29_10585	COG1172	Belongs to the binding-protein-dependent transport system permease family
NRZ29_10590	COG1129	ABC transporter
NRZ29_10595	COG1869	D-ribose catabolic process
NRZ29_10615	COG0037	tRNA processing
NRZ29_10620	COG0589	response to stress
NRZ29_10625	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
NRZ29_10650	COG2010	Cytochrome c
NRZ29_10665	COG3278	Belongs to the heme-copper respiratory oxidase family
NRZ29_10675	COG1956	GAF domain-containing protein
NRZ29_10680	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
NRZ29_10690	COG0308	aminopeptidase N
NRZ29_10700	COG2902	Dehydrogenase
NRZ29_10705	COG0167	dihydroorotate dehydrogenase activity
NRZ29_10715	COG0116	Belongs to the methyltransferase superfamily
NRZ29_10715	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
NRZ29_10725	COG0488	(ABC) transporter
NRZ29_10740	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
NRZ29_10745	COG1067	ATP-dependent peptidase activity
NRZ29_10755	COG3141	response to X-ray
NRZ29_10765	COG4221	oxidoreductase activity
NRZ29_10810	COG0372	Belongs to the citrate synthase family
NRZ29_10815	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
NRZ29_10825	COG2995	paraquat-inducible protein a
NRZ29_10830	COG3008	intermembrane lipid transfer
NRZ29_10835	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
NRZ29_10835	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
NRZ29_10850	COG0084	hydrolase, TatD family'
NRZ29_10855	COG0470	DNA polymerase III
NRZ29_10860	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
NRZ29_10865	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
NRZ29_10870	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
NRZ29_10880	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
NRZ29_10885	COG1028	Short-chain dehydrogenase reductase Sdr
NRZ29_10895	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
NRZ29_10900	COG0416	fatty acid biosynthetic process
NRZ29_10905	COG0333	Belongs to the bacterial ribosomal protein bL32 family
NRZ29_10910	COG1399	metal-binding, possibly nucleic acid-binding protein
NRZ29_10925	COG2814	Major facilitator Superfamily
NRZ29_10930	COG0424	maF-like protein
NRZ29_10940	COG0564	pseudouridine synthase activity
NRZ29_10945	COG1530	ribonuclease E activity
NRZ29_10950	COG0306	phosphate transporter
NRZ29_10955	COG0717	Belongs to the dCTP deaminase family
NRZ29_10960	COG0572	uridine kinase
NRZ29_10965	COG0489	protein tyrosine kinase activity
NRZ29_10970	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NRZ29_10970	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NRZ29_10975	COG0625	glutathione transferase activity
NRZ29_10980	COG1254	Belongs to the acylphosphatase family
NRZ29_10985	COG0840	transmembrane signaling receptor activity
NRZ29_10990	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
NRZ29_11005	COG0709	Synthesizes selenophosphate from selenide and ATP
NRZ29_11010	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
NRZ29_11015	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
NRZ29_11020	COG3437	response regulator, receiver
NRZ29_11030	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
NRZ29_11040	COG1643	Atp-dependent helicase
NRZ29_11045	COG0517	IMP dehydrogenase activity
NRZ29_11045	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
NRZ29_11045	COG0617	tRNA 3'-terminal CCA addition
NRZ29_11065	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
NRZ29_11075	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
NRZ29_11080	COG2832	Protein of unknown function (DUF454)
NRZ29_11085	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
NRZ29_11100	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
NRZ29_11105	COG0318	PFAM AMP-dependent synthetase and ligase
NRZ29_11110	COG0596	Alpha beta hydrolase
NRZ29_11110	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
NRZ29_11110	COG2226	methyltransferase
NRZ29_11120	COG1214	PFAM Peptidase M22, glycoprotease
NRZ29_11125	COG1199	ATP-dependent helicase activity
NRZ29_11135	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
NRZ29_11140	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
NRZ29_11145	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
NRZ29_11150	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
NRZ29_11150	COG0131	Imidazoleglycerol-phosphate dehydratase
NRZ29_11155	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
NRZ29_11160	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
NRZ29_11165	COG3437	response regulator, receiver
NRZ29_11170	COG2199	diguanylate cyclase activity
NRZ29_11175	COG0784	Response regulator, receiver
NRZ29_11175	COG2198	Histidine kinase
NRZ29_11175	COG2205	protein histidine kinase activity
NRZ29_11180	COG0107	imidazoleglycerol-phosphate synthase activity
NRZ29_11185	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
NRZ29_11185	COG0140	phosphoribosyl-ATP diphosphatase activity
NRZ29_11195	COG2378	regulation of single-species biofilm formation
NRZ29_11205	COG1288	antiporter activity
NRZ29_11215	COG3134	Outer membrane lipoprotein
NRZ29_11225	COG2080	2 iron, 2 sulfur cluster binding
NRZ29_11230	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
NRZ29_11235	COG1529	Aldehyde oxidase and xanthine dehydrogenase
NRZ29_11240	COG2252	PERMEase
NRZ29_11245	COG0402	S-adenosylhomocysteine deaminase activity
NRZ29_11250	COG2233	PERMEase
NRZ29_11255	COG1529	Aldehyde oxidase and xanthine dehydrogenase
NRZ29_11255	COG2080	2 iron, 2 sulfur cluster binding
NRZ29_11260	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
NRZ29_11265	COG0402	S-adenosylhomocysteine deaminase activity
NRZ29_11270	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
NRZ29_11270	COG0493	'glutamate synthase
NRZ29_11275	COG2068	MobA-Related Protein
NRZ29_11280	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
NRZ29_11285	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
NRZ29_11285	COG3608	succinylglutamate desuccinylase aspartoacylase
NRZ29_11290	COG0697	spore germination
NRZ29_11295	COG0549	Belongs to the carbamate kinase family
NRZ29_11305	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
NRZ29_11310	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
NRZ29_11315	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
NRZ29_11320	COG3829	transcription factor binding
NRZ29_11350	COG1250	3-hydroxyacyl-CoA dehydrogenase
NRZ29_11350	COG1024	Enoyl-CoA hydratase
NRZ29_11355	COG0183	Belongs to the thiolase family
NRZ29_11360	COG0714	Associated with various cellular activities
NRZ29_11390	COG1595	DNA-templated transcription, initiation
NRZ29_11405	COG2067	long-chain fatty acid transport protein
NRZ29_11410	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
NRZ29_11430	COG3123	guanosine phosphorylase activity
NRZ29_11435	COG1760	l-serine dehydratase
NRZ29_11440	COG1760	l-serine dehydratase
NRZ29_11445	COG2951	lytic endotransglycosylase activity
NRZ29_11450	COG3100	YcgL domain-containing protein
NRZ29_11455	COG0850	regulation of cytokinetic process
NRZ29_11460	COG2894	cell division
NRZ29_11465	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
NRZ29_11470	COG3099	Belongs to the UPF0263 family
NRZ29_11475	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
NRZ29_11520	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
NRZ29_11525	COG0697	spore germination
NRZ29_11530	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
NRZ29_11535	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
NRZ29_11545	COG0307	riboflavin synthase, alpha
NRZ29_11555	COG0534	Mate efflux family protein
NRZ29_11585	COG0417	DNA replication proofreading
NRZ29_11610	COG1560	Kdo2-lipid A biosynthetic process
NRZ29_11615	COG1560	Kdo2-lipid A biosynthetic process
NRZ29_11625	COG0583	DNA-binding transcription factor activity
NRZ29_11630	COG0673	inositol 2-dehydrogenase activity
NRZ29_11635	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
NRZ29_11650	COG0583	DNA-binding transcription factor activity
NRZ29_11660	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
NRZ29_11670	COG3300	MHYT domain
NRZ29_11670	COG5001	Diguanylate cyclase
NRZ29_11675	COG2723	6-phospho-beta-galactosidase activity
NRZ29_11680	COG0583	DNA-binding transcription factor activity
NRZ29_11720	COG0730	response to heat
NRZ29_11730	COG1028	Short-chain dehydrogenase reductase Sdr
NRZ29_11740	COG1024	Enoyl-CoA hydratase
NRZ29_11745	COG1024	Enoyl-CoA hydratase
NRZ29_11750	COG1960	acyl-CoA dehydrogenase activity
NRZ29_11760	COG1960	acyl-CoA dehydrogenase activity
NRZ29_11765	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
NRZ29_11800	COG1584	GPR1 FUN34 yaaH family protein
NRZ29_11815	COG1115	amino acid carrier protein
NRZ29_11850	COG1024	Enoyl-CoA hydratase
NRZ29_11865	COG3162	membrane
NRZ29_11870	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
NRZ29_11875	COG0488	(ABC) transporter
NRZ29_11880	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
NRZ29_11885	COG0776	regulation of translation
NRZ29_11890	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
NRZ29_11895	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
NRZ29_11900	COG0740	serine-type endopeptidase activity
NRZ29_11905	COG0544	peptidyl-prolyl cis-trans isomerase activity
NRZ29_11915	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
NRZ29_11920	COG4591	ABC-type transport system involved in lipoprotein release permease component
NRZ29_11925	COG1136	(ABC) transporter
NRZ29_11930	COG4591	ABC-type transport system involved in lipoprotein release permease component
NRZ29_11940	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
NRZ29_11945	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
NRZ29_11950	COG4166	transmembrane transport
NRZ29_11955	COG0697	spore germination
NRZ29_11965	COG2062	phosphohistidine phosphatase, SixA
NRZ29_12015	COG0519	Catalyzes the synthesis of GMP from XMP
NRZ29_12015	COG0518	GMP synthase (glutamine-hydrolyzing) activity
NRZ29_12020	COG0517	IMP dehydrogenase activity
NRZ29_12020	COG0516	GMP reductase activity
NRZ29_12025	COG3158	transport of potassium into the cell
NRZ29_12045	COG0697	spore germination
NRZ29_12050	COG1570	exodeoxyribonuclease VII activity
NRZ29_12065	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
NRZ29_12070	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
NRZ29_12075	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
NRZ29_12115	COG4771	TonB-dependent receptor
NRZ29_12120	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NRZ29_12125	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NRZ29_12130	COG1120	ATPase activity
NRZ29_12135	COG2977	Belongs to the P-Pant transferase superfamily
NRZ29_12140	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
NRZ29_12145	COG3033	Beta-eliminating lyase
NRZ29_12155	COG3046	protein related to deoxyribodipyrimidine photolyase
NRZ29_12160	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
NRZ29_12175	COG0516	GMP reductase activity
NRZ29_12175	COG0517	IMP dehydrogenase activity
NRZ29_12185	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
NRZ29_12200	COG4774	siderophore transport
NRZ29_12205	COG4977	sequence-specific DNA binding
NRZ29_12215	COG0583	DNA-binding transcription factor activity
NRZ29_12220	COG2910	NAD(P)H-binding
NRZ29_12235	COG0612	Peptidase, M16
NRZ29_12240	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
NRZ29_12250	COG1944	ATP diphosphatase activity
NRZ29_12255	COG2116	formate transmembrane transporter activity
NRZ29_12260	COG1882	Formate acetyltransferase
NRZ29_12265	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
NRZ29_12270	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
NRZ29_12275	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
NRZ29_12285	COG1840	ABC-type Fe3 transport system, periplasmic component
NRZ29_12290	COG3842	ATPase activity
NRZ29_12300	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
NRZ29_12305	COG2983	Belongs to the UPF0260 family
NRZ29_12315	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
NRZ29_12320	COG0045	succinate-CoA ligase (ADP-forming) activity
NRZ29_12325	COG0508	dehydrogenase complex catalyzes the overall conversion of
NRZ29_12330	COG0567	Dehydrogenase, E1 component
NRZ29_12340	COG1053	succinate dehydrogenase
NRZ29_12345	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
NRZ29_12370	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
NRZ29_12375	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
NRZ29_12375	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
NRZ29_12385	COG3069	C4-dicarboxylate transmembrane transporter activity
NRZ29_12400	COG1451	nucleotide metabolic process
NRZ29_12415	COG0254	rRNA binding
NRZ29_12420	COG0257	Belongs to the bacterial ribosomal protein bL36 family
NRZ29_12430	COG0583	DNA-binding transcription factor activity
NRZ29_12440	COG1172	Belongs to the binding-protein-dependent transport system permease family
NRZ29_12450	COG1879	ABC-type sugar transport system periplasmic component
NRZ29_12455	COG1069	ribulokinase activity
NRZ29_12465	COG2160	L-arabinose isomerase activity
NRZ29_12470	COG2925	Exonuclease
NRZ29_12480	COG3345	alpha-galactosidase
NRZ29_12485	COG1380	Effector of murein hydrolase LrgA
NRZ29_12490	COG1346	cytolysis
NRZ29_12495	COG0295	cytidine deaminase activity
NRZ29_12500	COG1022	Amp-dependent synthetase and ligase
NRZ29_12515	COG0861	Integral membrane protein TerC family
NRZ29_12520	COG2885	chlorophyll binding
NRZ29_12525	COG2199	diguanylate cyclase activity
NRZ29_12540	COG2154	pterin-4-alpha-carbinolamine dehydratase
NRZ29_12550	COG3768	UPF0283 membrane protein
NRZ29_12555	COG3106	COG3106 Predicted ATPase
NRZ29_12570	COG1842	Phage shock protein A
NRZ29_12575	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
NRZ29_12585	COG4168	peptide transport system, permease
NRZ29_12590	COG4171	peptide transport system, permease
NRZ29_12600	COG4172	Belongs to the ABC transporter superfamily
NRZ29_12610	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
NRZ29_12615	COG1286	toxin biosynthetic process
NRZ29_12620	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
NRZ29_12625	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
NRZ29_12630	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
NRZ29_12635	COG0531	amino acid
NRZ29_12635	COG1674	ftsk spoiiie
NRZ29_12645	COG0686	Belongs to the AlaDH PNT family
NRZ29_12650	COG0492	ferredoxin-NADP+ reductase activity
NRZ29_12655	COG3706	GGDEF domain
NRZ29_12660	COG3134	Outer membrane lipoprotein
NRZ29_12665	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
NRZ29_12670	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
NRZ29_12675	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
NRZ29_12680	COG0542	response to heat
NRZ29_12685	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
NRZ29_12690	COG1278	Cold shock
NRZ29_12695	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
NRZ29_12775	COG3829	transcription factor binding
NRZ29_12850	COG3501	Rhs element vgr protein
NRZ29_12880	COG1435	thymidine kinase activity
NRZ29_12885	COG1757	Na H antiporter
NRZ29_12890	COG2916	Histone family protein nucleoid-structuring protein H-NS
NRZ29_12895	COG2096	Adenosyltransferase
NRZ29_12900	COG3530	Putative quorum-sensing-regulated virulence factor
NRZ29_12905	COG0602	queuosine metabolic process
NRZ29_12910	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
NRZ29_12930	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
NRZ29_12940	COG0776	regulation of translation
NRZ29_12945	COG0539	negative regulation of cytoplasmic translation
NRZ29_12950	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
NRZ29_12955	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
NRZ29_12965	COG0583	DNA-binding transcription factor activity
NRZ29_12985	COG0778	Nitroreductase
NRZ29_12990	COG3300	MHYT domain
NRZ29_12990	COG5001	Diguanylate cyclase
NRZ29_13000	COG0583	DNA-binding transcription factor activity
NRZ29_13005	COG3437	response regulator, receiver
NRZ29_13030	COG4989	oxidoreductase activity
NRZ29_13035	COG0724	RNA recognition motif
NRZ29_13055	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
NRZ29_13075	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
NRZ29_13080	COG1360	Flagellar Motor Protein
NRZ29_13085	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
NRZ29_13090	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
NRZ29_13095	COG0649	NAD binding
NRZ29_13095	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
NRZ29_13110	COG1034	ATP synthesis coupled electron transport
NRZ29_13115	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
NRZ29_13120	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
NRZ29_13125	COG0839	Belongs to the complex I subunit 6 family
NRZ29_13130	COG0713	ATP synthesis coupled electron transport
NRZ29_13140	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
NRZ29_13145	COG1007	ATP synthesis coupled electron transport
NRZ29_13150	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
NRZ29_13150	COG0047	phosphoribosylformylglycinamidine synthase activity
NRZ29_13155	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
NRZ29_13160	COG1645	bacterial-type flagellum-dependent swarming motility
NRZ29_13165	COG1160	GTP binding
NRZ29_13170	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
NRZ29_13175	COG2976	Protein conserved in bacteria
NRZ29_13180	COG0124	histidyl-tRNA synthetase
NRZ29_13185	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
NRZ29_13200	COG0820	rRNA (adenine-C2-)-methyltransferase activity
NRZ29_13205	COG0105	UTP biosynthetic process
NRZ29_13210	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
NRZ29_13220	COG0633	Ferredoxin
NRZ29_13225	COG0443	Heat shock 70 kDa protein
NRZ29_13230	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
NRZ29_13240	COG0822	iron-sulfur transferase activity
NRZ29_13245	COG1104	cysteine desulfurase activity
NRZ29_13265	COG3154	lipid carrier protein
NRZ29_13270	COG0826	peptidase U32
NRZ29_13275	COG0826	peptidase U32
NRZ29_13290	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
NRZ29_13295	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
NRZ29_13300	COG1862	Preprotein translocase
NRZ29_13305	COG0343	queuine tRNA-ribosyltransferase activity
NRZ29_13310	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
NRZ29_13315	COG0517	IMP dehydrogenase activity
NRZ29_13325	COG3634	alkyl hydroperoxide reductase activity
NRZ29_13335	COG3852	Histidine kinase
NRZ29_13350	COG1393	Belongs to the ArsC family
NRZ29_13355	COG0798	PFAM Bile acid sodium symporter
NRZ29_13360	COG0640	Transcriptional regulator
NRZ29_13365	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
NRZ29_13365	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
NRZ29_13370	COG0509	glycine decarboxylation via glycine cleavage system
NRZ29_13375	COG0404	The glycine cleavage system catalyzes the degradation of glycine
NRZ29_13380	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
NRZ29_13385	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
NRZ29_13405	COG2814	Major facilitator Superfamily
NRZ29_13410	COG0625	glutathione transferase activity
NRZ29_13420	COG0483	inositol monophosphate 1-phosphatase activity
NRZ29_13440	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
NRZ29_13485	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
NRZ29_13500	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
NRZ29_13500	COG0301	tRNA thio-modification
NRZ29_13510	COG4953	penicillin-binding protein 1C
NRZ29_13515	COG2373	Large extracellular alpha-helical protein
NRZ29_13520	COG0446	pyridine nucleotide-disulphide oxidoreductase
NRZ29_13530	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
NRZ29_13550	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
NRZ29_13560	COG2431	L-lysine efflux transmembrane transporter activity
NRZ29_13565	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
NRZ29_13570	COG3124	Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP
NRZ29_13585	COG1393	Belongs to the ArsC family
NRZ29_13590	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
NRZ29_13595	COG4783	chaperone-mediated protein folding
NRZ29_13600	COG0425	Belongs to the sulfur carrier protein TusA family
NRZ29_13625	COG3842	ATPase activity
NRZ29_13630	COG3833	ABC-type maltose transport systems, permease component
NRZ29_13635	COG1175	transmembrane transport
NRZ29_13645	COG3081	Nucleoid-associated protein
NRZ29_13650	COG3082	Protein of unknown function (DUF1414)
NRZ29_13655	COG3083	sulfuric ester hydrolase activity
NRZ29_13660	COG4771	TonB-dependent receptor
NRZ29_13665	COG1770	oligopeptidase
NRZ29_13685	COG4574	serine-type endopeptidase inhibitor activity
NRZ29_13690	COG3085	chromosome segregation
NRZ29_13695	COG0583	DNA-binding transcription factor activity
NRZ29_13700	COG1605	Chorismate mutase
NRZ29_13700	COG0287	Prephenate dehydrogenase
NRZ29_13705	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
NRZ29_13710	COG0584	glycerophosphoryl diester phosphodiesterase
NRZ29_13720	COG1349	DNA-binding transcription factor activity
NRZ29_13725	COG2271	Major facilitator Superfamily
NRZ29_13730	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
NRZ29_13735	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
NRZ29_13740	COG0583	DNA-binding transcription factor activity
NRZ29_13765	COG0656	L-ascorbic acid biosynthetic process
NRZ29_13770	COG2814	Major facilitator Superfamily
NRZ29_13780	COG1294	oxidase, subunit
NRZ29_13790	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
NRZ29_13800	COG2979	Protein of unknown function (DUF533)
NRZ29_13825	COG2271	Major facilitator Superfamily
NRZ29_13830	COG0583	DNA-binding transcription factor activity
NRZ29_13840	COG2807	transmembrane transport
NRZ29_13850	COG1187	pseudouridine synthase activity
NRZ29_13880	COG0346	lactoylglutathione lyase activity
NRZ29_13890	COG1403	HNH endonuclease
NRZ29_13905	COG3681	Belongs to the UPF0597 family
NRZ29_13915	COG0814	amino acid
NRZ29_13935	COG1166	arginine decarboxylase activity
NRZ29_13945	COG2195	Cleaves the N-terminal amino acid of tripeptides
NRZ29_13975	COG0583	DNA-binding transcription factor activity
NRZ29_13985	COG2759	Belongs to the formate--tetrahydrofolate ligase family
NRZ29_13990	COG0840	transmembrane signaling receptor activity
NRZ29_13995	COG0302	gtp cyclohydrolase
NRZ29_14005	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
NRZ29_14010	COG2267	carboxylic ester hydrolase activity
NRZ29_14015	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
NRZ29_14030	COG0314	molybdopterin synthase activity
NRZ29_14035	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
NRZ29_14040	COG0315	cyclic pyranopterin monophosphate synthase activity
NRZ29_14045	COG0521	Mo-molybdopterin cofactor biosynthetic process
NRZ29_14050	COG3005	denitrification pathway
NRZ29_14060	COG0348	domain, Protein
NRZ29_14065	COG0437	4 iron, 4 sulfur cluster binding
NRZ29_14070	COG0243	molybdopterin cofactor binding
NRZ29_14080	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
NRZ29_14080	COG1149	4fe-4S ferredoxin, iron-sulfur binding domain protein
NRZ29_14085	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
NRZ29_14090	COG3850	Histidine kinase
NRZ29_14095	COG2197	response regulator
NRZ29_14125	COG0121	glutamine amidotransferase
NRZ29_14130	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
NRZ29_14135	COG1960	acyl-CoA dehydrogenase activity
NRZ29_14140	COG0784	Response regulator, receiver
NRZ29_14140	COG3437	response regulator, receiver
NRZ29_14155	COG0328	RNA-DNA hybrid ribonuclease activity
NRZ29_14160	COG2226	methyltransferase
NRZ29_14165	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
NRZ29_14170	COG1388	LysM domain
NRZ29_14170	COG0741	lytic transglycosylase activity
NRZ29_14175	COG3021	interspecies interaction between organisms
NRZ29_14185	COG1607	acyl-coa hydrolase
NRZ29_14200	COG0741	lytic transglycosylase activity
NRZ29_14210	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
NRZ29_14235	COG0729	surface antigen
NRZ29_14245	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
NRZ29_14250	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
NRZ29_14260	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
NRZ29_14270	COG4134	Bacterial extracellular solute-binding protein
NRZ29_14280	COG4136	ATPase activity
NRZ29_14285	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
NRZ29_14290	COG2951	lytic endotransglycosylase activity
NRZ29_14295	COG1846	Transcriptional regulator
NRZ29_14305	COG0033	Phosphoglucomutase
NRZ29_14310	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
NRZ29_14315	COG0596	Alpha beta hydrolase
NRZ29_14330	COG0716	FMN binding
NRZ29_14340	COG0735	belongs to the Fur family
NRZ29_14345	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
NRZ29_14355	COG1263	PTS System
NRZ29_14355	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
NRZ29_14355	COG2190	(PTS) system
NRZ29_14360	COG0363	glucosamine-6-phosphate deaminase activity
NRZ29_14365	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
NRZ29_14370	COG1940	carbohydrate kinase activity
NRZ29_14370	COG1846	Transcriptional regulator
NRZ29_14385	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
NRZ29_14405	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
NRZ29_14440	COG1091	dTDP-4-dehydrorhamnose reductase activity
NRZ29_14455	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
NRZ29_14460	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NRZ29_14465	COG1309	transcriptional regulator
NRZ29_14480	COG1946	Acyl-CoA thioesterase
NRZ29_14490	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
NRZ29_14500	COG0009	L-threonylcarbamoyladenylate synthase
NRZ29_14510	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
NRZ29_14515	COG0512	Glutamine amidotransferase of anthranilate synthase
NRZ29_14515	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
NRZ29_14520	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
NRZ29_14525	COG0134	indole-3-glycerol-phosphate synthase activity
NRZ29_14525	COG0135	phosphoribosylanthranilate isomerase activity
NRZ29_14530	COG0133	tryptophan synthase activity
NRZ29_14535	COG0159	tryptophan synthase activity
NRZ29_14555	COG1988	membrane-bound metal-dependent
NRZ29_14575	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
NRZ29_14585	COG4521	taurine ABC transporter
NRZ29_14590	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
NRZ29_14595	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
NRZ29_14600	COG2175	clavaminate synthase activity
NRZ29_14610	COG2814	Major facilitator Superfamily
NRZ29_14615	COG0109	protoheme IX farnesyltransferase activity
NRZ29_14620	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
NRZ29_14625	COG1845	cytochrome c oxidase, subunit III
NRZ29_14630	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
NRZ29_14635	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
NRZ29_14680	COG2211	Major facilitator Superfamily
NRZ29_14695	COG0708	Exodeoxyribonuclease III
NRZ29_14715	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NRZ29_14720	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
NRZ29_14740	COG0095	Lipoate-protein ligase
NRZ29_14780	COG0446	pyridine nucleotide-disulphide oxidoreductase
NRZ29_14790	COG1285	pathogenesis
NRZ29_14820	COG0484	heat shock protein binding
NRZ29_14825	COG0443	Heat shock 70 kDa protein
NRZ29_14830	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
NRZ29_14835	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
NRZ29_14840	COG0497	DNA recombination
NRZ29_14845	COG1227	inorganic diphosphatase activity
NRZ29_14855	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NRZ29_14860	COG1136	(ABC) transporter
NRZ29_14860	COG0577	efflux transmembrane transporter activity
NRZ29_14870	COG2375	cellular response to nickel ion
NRZ29_14875	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
NRZ29_14910	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
NRZ29_14915	COG1917	Cupin 2, conserved barrel domain protein
NRZ29_14915	COG1396	sequence-specific DNA binding
NRZ29_14935	COG0531	amino acid
NRZ29_14945	COG0531	amino acid
NRZ29_14955	COG1283	sodium-dependent phosphate transmembrane transporter activity
NRZ29_14965	COG3384	dioxygenase
NRZ29_14970	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
NRZ29_14970	COG2205	protein histidine kinase activity
NRZ29_14990	COG0813	purine-nucleoside phosphorylase activity
NRZ29_15005	COG0488	(ABC) transporter
NRZ29_15020	COG4319	ketosteroid isomerase
NRZ29_15025	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
NRZ29_15030	COG0083	homoserine kinase activity
NRZ29_15040	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
NRZ29_15045	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
NRZ29_15060	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
NRZ29_15070	COG0745	RESPONSE REGULATOR receiver
NRZ29_15085	COG4988	ABC transporter
NRZ29_15090	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
NRZ29_15110	COG1720	tRNA m6t6A37 methyltransferase activity
NRZ29_15115	COG3437	response regulator, receiver
NRZ29_15115	COG2770	Histidine kinase
NRZ29_15130	COG0542	response to heat
NRZ29_15135	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
NRZ29_15140	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
NRZ29_15150	COG2190	(PTS) system
NRZ29_15165	COG3038	cytochrome b561
NRZ29_15175	COG0419	ATPase involved in DNA repair
NRZ29_15180	COG0420	3'-5' exonuclease activity
NRZ29_15190	COG2974	May be involved in recombination
NRZ29_15200	COG4651	solute:proton antiporter activity
NRZ29_15200	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
NRZ29_15215	COG0469	pyruvate kinase activity
NRZ29_15220	COG1196	nuclear chromosome segregation
NRZ29_15220	COG3264	Mechanosensitive ion channel
NRZ29_15230	COG2706	6-phosphogluconolactonase activity
NRZ29_15250	COG0281	malic enzyme
NRZ29_15265	COG0437	4 iron, 4 sulfur cluster binding
NRZ29_15270	COG3383	formate dehydrogenase (NAD+) activity
NRZ29_15270	COG3383	formate dehydrogenase (NAD+) activity
NRZ29_15305	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
NRZ29_15310	COG1910	domain protein
NRZ29_15315	COG3852	Histidine kinase
NRZ29_15320	COG2204	response regulator
NRZ29_15330	COG4662	Binding-protein-dependent transport system inner membrane component
NRZ29_15340	COG0746	molybdenum cofactor guanylyltransferase activity
NRZ29_15345	COG0303	'Molybdopterin
NRZ29_15350	COG1289	transmembrane transporter activity
NRZ29_15355	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
NRZ29_15390	COG3220	belongs to the UPF0276 family
NRZ29_15420	COG2205	protein histidine kinase activity
NRZ29_15420	COG0784	Response regulator, receiver
NRZ29_15425	COG4166	transmembrane transport
NRZ29_15430	COG0601	transmembrane transport
NRZ29_15435	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
NRZ29_15440	COG0444	Belongs to the ABC transporter superfamily
NRZ29_15445	COG4608	Belongs to the ABC transporter superfamily
NRZ29_15455	COG2971	BadF BadG BcrA BcrD
NRZ29_15465	COG0840	transmembrane signaling receptor activity
NRZ29_15485	COG3724	N-succinylarginine dihydrolase activity
NRZ29_15490	COG0616	signal peptide processing
NRZ29_15495	COG1028	Short-chain dehydrogenase reductase Sdr
NRZ29_15500	COG0583	DNA-binding transcription factor activity
NRZ29_15510	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
NRZ29_15520	COG0583	DNA-binding transcription factor activity
NRZ29_15525	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
NRZ29_15530	COG1881	PFAM PEBP family protein
NRZ29_15540	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
NRZ29_15540	COG3408	Glycogen debranching enzyme
NRZ29_15545	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
NRZ29_15550	COG0739	heme binding
NRZ29_15555	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
NRZ29_15575	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
NRZ29_15585	COG3091	SprT-like family
NRZ29_15595	COG1385	rRNA (uridine-N3-)-methyltransferase activity
NRZ29_15600	COG0189	ligase activity
NRZ29_15610	COG1678	Uncharacterized ACR, COG1678
NRZ29_15615	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
NRZ29_15620	COG3104	oligopeptide transport
NRZ29_15630	COG0714	Associated with various cellular activities
NRZ29_15645	COG1115	amino acid carrier protein
NRZ29_15650	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
NRZ29_15665	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
NRZ29_15675	COG1301	dicarboxylic acid transport
NRZ29_15685	COG2912	Transglutaminase-like superfamily
NRZ29_15695	COG2890	protein-(glutamine-N5) methyltransferase activity
NRZ29_15700	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
NRZ29_15705	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
NRZ29_15710	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
NRZ29_15715	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
NRZ29_15725	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
NRZ29_15730	COG0737	Belongs to the 5'-nucleotidase family
NRZ29_15735	COG0193	aminoacyl-tRNA hydrolase activity
NRZ29_15740	COG0012	GTP binding
NRZ29_15785	COG0490	domain, Protein
NRZ29_15785	COG0471	metal ion transport
NRZ29_15805	COG3097	Belongs to the UPF0267 family
NRZ29_15815	COG0366	Alpha amylase catalytic
NRZ29_15825	COG0674	pyruvate-flavodoxin oxidoreductase activity
NRZ29_15825	COG1013	pyruvate-flavodoxin oxidoreductase activity
NRZ29_15825	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
NRZ29_15825	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
NRZ29_15835	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
NRZ29_15845	COG1012	belongs to the aldehyde dehydrogenase family
NRZ29_15855	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
NRZ29_15870	COG0180	Tryptophanyl-tRNA synthetase
NRZ29_15880	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
NRZ29_15890	COG0338	D12 class N6 adenine-specific DNA methyltransferase
NRZ29_15900	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
NRZ29_15905	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
NRZ29_15935	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
NRZ29_15940	COG0583	DNA-binding transcription factor activity
NRZ29_15945	COG0840	transmembrane signaling receptor activity
NRZ29_15960	COG0583	DNA-binding transcription factor activity
NRZ29_15975	COG0739	heme binding
NRZ29_15985	COG1511	domain protein
NRZ29_15985	COG3264	Mechanosensitive ion channel
NRZ29_15990	COG0584	glycerophosphoryl diester phosphodiesterase
NRZ29_16000	COG1053	succinate dehydrogenase
NRZ29_16005	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
NRZ29_16010	COG3029	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
NRZ29_16035	COG3214	Protein conserved in bacteria
NRZ29_16040	COG4106	trans-aconitate 2-methyltransferase activity
NRZ29_16075	COG0642	Histidine kinase
NRZ29_16085	COG0516	GMP reductase activity
NRZ29_16095	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
NRZ29_16100	COG3647	Membrane
NRZ29_16110	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NRZ29_16130	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
NRZ29_16140	COG0583	DNA-binding transcription factor activity
NRZ29_16145	COG3706	GGDEF domain
NRZ29_16155	COG1335	isochorismatase
NRZ29_16160	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
NRZ29_16165	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
NRZ29_16170	COG1702	phosphate starvation-inducible protein PhoH
NRZ29_16175	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
NRZ29_16180	COG4535	Mg2 and Co2 transporter CorC
NRZ29_16185	COG0815	Transfers the fatty acyl group on membrane lipoproteins
NRZ29_16190	COG2888	peptidyl-tyrosine sulfation
NRZ29_16195	COG0495	leucyl-tRNA aminoacylation
NRZ29_16210	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
NRZ29_16215	COG0799	negative regulation of ribosome biogenesis
NRZ29_16220	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
NRZ29_16225	COG0768	penicillin binding
NRZ29_16230	COG0772	Belongs to the SEDS family
NRZ29_16235	COG2951	lytic endotransglycosylase activity
NRZ29_16240	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
NRZ29_16245	COG1686	Belongs to the peptidase S11 family
NRZ29_16250	COG2921	Belongs to the UPF0250 family
NRZ29_16255	COG0321	lipoyl(octanoyl) transferase activity
NRZ29_16260	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
NRZ29_16270	COG3545	Serine hydrolase
NRZ29_16275	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
NRZ29_16290	COG0789	Transcriptional regulator
NRZ29_16300	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
NRZ29_16305	COG1970	mechanosensitive ion channel activity
NRZ29_16310	COG4974	Belongs to the 'phage' integrase family
NRZ29_16320	COG0312	modulator of DNA gyrase
NRZ29_16325	COG0312	modulator of DNA gyrase
NRZ29_16390	COG3275	phosphorelay sensor kinase activity
NRZ29_16395	COG3279	Response regulator of the LytR AlgR family
NRZ29_16400	COG1966	Carbon starvation protein
NRZ29_16410	COG0114	fumarate hydratase activity
NRZ29_16420	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
NRZ29_16425	COG3706	GGDEF domain
NRZ29_16430	COG2211	Major facilitator Superfamily
NRZ29_16435	COG1185	polyribonucleotide nucleotidyltransferase activity
NRZ29_16440	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
NRZ29_16445	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
NRZ29_16450	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
NRZ29_16455	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
NRZ29_16460	COG0195	Participates in both transcription termination and antitermination
NRZ29_16465	COG0779	Required for maturation of 30S ribosomal subunits
NRZ29_16480	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
NRZ29_16485	COG0149	triose-phosphate isomerase activity
NRZ29_16490	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
NRZ29_16495	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
NRZ29_16505	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
NRZ29_16510	COG1534	Rna-binding protein
NRZ29_16525	COG1360	Flagellar Motor Protein
NRZ29_16530	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
NRZ29_16535	COG1722	exodeoxyribonuclease VII activity
NRZ29_16540	COG0142	geranyltranstransferase activity
NRZ29_16545	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
NRZ29_16555	COG0601	transmembrane transport
NRZ29_16565	COG4172	Belongs to the ABC transporter superfamily
NRZ29_16570	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
NRZ29_16575	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
NRZ29_16580	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
NRZ29_16585	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
NRZ29_16605	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
NRZ29_16605	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
NRZ29_16610	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
NRZ29_16625	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
NRZ29_16640	COG3381	protein complex oligomerization
NRZ29_16660	COG3300	MHYT domain
NRZ29_16660	COG5001	Diguanylate cyclase
NRZ29_16670	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
NRZ29_16675	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
NRZ29_16680	COG0511	ligase activity, forming carbon-carbon bonds
NRZ29_16685	COG0439	Biotin carboxylase
NRZ29_16695	COG4145	pantothenate transmembrane transporter activity
NRZ29_16700	COG1263	PTS System
NRZ29_16700	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
NRZ29_16700	COG2190	(PTS) system
NRZ29_16705	COG0583	DNA-binding transcription factor activity
NRZ29_16710	COG0604	alcohol dehydrogenase
NRZ29_16715	COG2264	protein methyltransferase activity
NRZ29_16740	COG0778	Nitroreductase
NRZ29_16745	COG1902	pentaerythritol trinitrate reductase activity
NRZ29_16745	COG0446	pyridine nucleotide-disulphide oxidoreductase
NRZ29_16750	COG0616	signal peptide processing
NRZ29_16770	COG3139	Protein of unknown function (DUF1315)
NRZ29_16775	COG0252	asparaginase activity
NRZ29_16780	COG0786	glutamate:sodium symporter activity
NRZ29_16795	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
NRZ29_16800	COG0384	phenazine biosynthesis protein PhzF
NRZ29_16805	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
NRZ29_16810	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
NRZ29_16815	COG0175	sulfate reduction
NRZ29_16820	COG2113	Glycine betaine
NRZ29_16825	COG4176	ABC-type proline glycine betaine transport system permease component
NRZ29_16830	COG4175	Glycine betaine
NRZ29_16840	COG3610	response to peptide
NRZ29_16845	COG2966	Psort location CytoplasmicMembrane, score
NRZ29_16855	COG0521	Mo-molybdopterin cofactor biosynthetic process
NRZ29_16865	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
NRZ29_16870	COG1028	Short-chain dehydrogenase reductase Sdr
NRZ29_16880	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
NRZ29_16905	COG2986	histidine ammonia-lyase
NRZ29_16930	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
NRZ29_16935	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
NRZ29_16970	COG1858	cytochrome C peroxidase
NRZ29_16980	COG2313	pseudouridylate synthase activity
NRZ29_16985	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
NRZ29_17020	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
NRZ29_17035	COG1073	alpha beta
NRZ29_17040	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
NRZ29_17045	COG2195	Cleaves the N-terminal amino acid of tripeptides
NRZ29_17050	COG4608	Belongs to the ABC transporter superfamily
NRZ29_17055	COG0444	Belongs to the ABC transporter superfamily
NRZ29_17065	COG4239	(ABC) transporter, permease
NRZ29_17070	COG4174	ABC transporter (Permease)
NRZ29_17085	COG0811	peptide transport
NRZ29_17090	COG0811	peptide transport
NRZ29_17095	COG0848	biopolymer transport protein
NRZ29_17145	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
NRZ29_17150	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
NRZ29_17155	COG0840	transmembrane signaling receptor activity
NRZ29_17165	COG1278	Cold shock
NRZ29_17200	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
NRZ29_17205	COG1162	GTPase activity
NRZ29_17210	COG0688	phosphatidylethanolamine metabolic process
NRZ29_17215	COG4628	conserved protein (DUF2132)
NRZ29_17235	COG5001	Diguanylate cyclase
NRZ29_17235	COG3300	MHYT domain
NRZ29_17240	COG3076	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome
NRZ29_17270	COG1132	(ABC) transporter
NRZ29_17280	COG2897	thiosulfate sulfurtransferase activity
NRZ29_17285	COG2066	Belongs to the glutaminase family
NRZ29_17290	COG3171	Protein conserved in bacteria
NRZ29_17295	COG0220	tRNA (guanine-N7-)-methyltransferase activity
NRZ29_17300	COG2234	aminopeptidase activity
NRZ29_17300	COG4935	Belongs to the peptidase S8 family
NRZ29_17305	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
NRZ29_17310	COG2200	EAL domain
NRZ29_17315	COG1090	epimerase
NRZ29_17320	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
NRZ29_17325	COG4181	ATPase activity
NRZ29_17330	COG2755	lipolytic protein G-D-S-L family
NRZ29_17335	COG0835	chemotaxis
NRZ29_17335	COG0784	Response regulator, receiver
NRZ29_17355	COG0569	domain protein
NRZ29_17355	COG2985	domain, Protein
NRZ29_17360	COG1272	protein, Hemolysin III
NRZ29_17365	COG0076	glutamate decarboxylase activity
NRZ29_17370	COG2917	probably involved in intracellular septation
NRZ29_17375	COG2350	Protein conserved in bacteria
NRZ29_17385	COG1555	photosystem II stabilization
NRZ29_17390	COG1210	Utp--glucose-1-phosphate uridylyltransferase
NRZ29_17395	COG3104	oligopeptide transport
NRZ29_17400	COG0745	RESPONSE REGULATOR receiver
NRZ29_17430	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NRZ29_17445	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
NRZ29_17450	COG1280	lysine exporter protein (LysE YggA)
NRZ29_17475	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
NRZ29_17480	COG0564	pseudouridine synthase activity
NRZ29_17490	COG5001	Diguanylate cyclase
NRZ29_17490	COG3300	MHYT domain
NRZ29_17500	COG0459	protein refolding
NRZ29_17505	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
NRZ29_17510	COG0534	Mate efflux family protein
NRZ29_17515	COG3030	protein affecting phage T7 exclusion by the F plasmid
NRZ29_17520	COG1027	Aspartate ammonia-lyase
NRZ29_17525	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
NRZ29_17535	COG0477	Major facilitator Superfamily
NRZ29_17550	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
NRZ29_17555	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
NRZ29_17565	COG0673	inositol 2-dehydrogenase activity
NRZ29_17575	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
NRZ29_17580	COG0635	Involved in the biosynthesis of porphyrin-containing compound
NRZ29_17585	COG3036	rescue of stalled ribosome
NRZ29_17590	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
NRZ29_17600	COG0138	bifunctional purine biosynthesis protein purh
NRZ29_17605	COG0151	Belongs to the GarS family
NRZ29_17630	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
NRZ29_17635	COG0358	DNA primase activity
NRZ29_17640	COG1610	YqeY-like protein
NRZ29_17645	COG0828	Belongs to the bacterial ribosomal protein bS21 family
NRZ29_17650	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
NRZ29_17665	COG1238	metal cluster binding
NRZ29_17670	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
NRZ29_17675	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
NRZ29_17680	COG0585	pseudouridine synthase activity
NRZ29_17690	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
NRZ29_17695	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
NRZ29_17700	COG0148	phosphopyruvate hydratase activity
NRZ29_17705	COG0504	CTP synthase activity
NRZ29_17710	COG3956	TIGRFAM MazG family protein
NRZ29_17715	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
NRZ29_17720	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
NRZ29_17730	COG4807	Protein conserved in bacteria
NRZ29_17735	COG3023	N-Acetylmuramoyl-L-alanine amidase
NRZ29_17740	COG1349	DNA-binding transcription factor activity
NRZ29_17750	COG2222	sugar isomerase
NRZ29_17755	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
NRZ29_17765	COG3716	PTS system mannose fructose sorbose family IID component
NRZ29_17770	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
NRZ29_17775	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
NRZ29_17790	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
NRZ29_17795	COG1381	Involved in DNA repair and RecF pathway recombination
NRZ29_17805	COG0571	ribonuclease III activity
NRZ29_17810	COG0681	Belongs to the peptidase S26 family
NRZ29_17815	COG0481	GTPase activity
NRZ29_17830	COG3073	An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E
NRZ29_17835	COG1595	DNA-templated transcription, initiation
NRZ29_17840	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
NRZ29_17850	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
NRZ29_17895	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
NRZ29_17905	COG0126	phosphoglycerate kinase activity
NRZ29_17910	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
NRZ29_17915	COG1940	carbohydrate kinase activity
NRZ29_17920	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
NRZ29_17935	COG4991	sh3 domain protein
NRZ29_17940	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
NRZ29_17955	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
NRZ29_17960	COG1028	Short-chain dehydrogenase reductase Sdr
NRZ29_17975	COG1505	serine-type exopeptidase activity
NRZ29_17980	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
NRZ29_17985	COG0765	amino acid transport
NRZ29_17990	COG0765	amino acid transport
NRZ29_17995	COG1126	abc transporter atp-binding protein
NRZ29_18000	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
NRZ29_18005	COG1136	(ABC) transporter
NRZ29_18005	COG0577	efflux transmembrane transporter activity
NRZ29_18010	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NRZ29_18015	COG0745	RESPONSE REGULATOR receiver
NRZ29_18020	COG2205	protein histidine kinase activity
NRZ29_18025	COG2816	NAD+ diphosphatase activity
NRZ29_18060	COG2070	2-Nitropropane dioxygenase
NRZ29_18085	COG1912	Pfam S-adenosyl-l-methionine hydroxide adenosyltransferase
NRZ29_18110	COG3706	GGDEF domain
NRZ29_18115	COG0513	Belongs to the DEAD box helicase family
NRZ29_18135	COG0154	amidase activity
NRZ29_18140	COG2957	Belongs to the agmatine deiminase family
NRZ29_18150	COG2852	Protein conserved in bacteria
NRZ29_18160	COG1902	pentaerythritol trinitrate reductase activity
NRZ29_18195	COG5001	Diguanylate cyclase
NRZ29_18195	COG3300	MHYT domain
NRZ29_18205	COG0714	Associated with various cellular activities
NRZ29_18215	COG0456	acetyltransferase
NRZ29_18225	COG1022	Amp-dependent synthetase and ligase
NRZ29_18235	COG2918	glutathione biosynthetic process
NRZ29_18240	COG0612	Peptidase, M16
NRZ29_18245	COG1238	metal cluster binding
NRZ29_18270	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
NRZ29_18275	COG0359	binds to the 23S rRNA
NRZ29_18280	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
NRZ29_18285	COG0360	Binds together with S18 to 16S ribosomal RNA
NRZ29_18290	COG1914	H( )-stimulated, divalent metal cation uptake system
NRZ29_18310	COG2153	protein acetylation
NRZ29_18320	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
NRZ29_18325	COG0557	exoribonuclease II activity
NRZ29_18330	COG3706	GGDEF domain
NRZ29_18335	COG1854	S-ribosylhomocysteine lyase activity
NRZ29_18350	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
NRZ29_18350	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
NRZ29_18390	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
NRZ29_18395	COG1047	Peptidyl-prolyl cis-trans
NRZ29_18400	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
NRZ29_18405	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
NRZ29_18410	COG0196	riboflavin kinase activity
NRZ29_18420	COG0728	peptidoglycan biosynthetic process
NRZ29_18425	COG0268	Binds directly to 16S ribosomal RNA
NRZ29_18430	COG0640	Transcriptional regulator
NRZ29_18435	COG0583	DNA-binding transcription factor activity
NRZ29_18445	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
NRZ29_18450	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
NRZ29_18455	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
NRZ29_18465	COG1051	belongs to the nudix hydrolase family
NRZ29_18470	COG3066	DNA modification
NRZ29_18480	COG0335	large ribosomal subunit rRNA binding
NRZ29_18485	COG0336	Belongs to the RNA methyltransferase TrmD family
NRZ29_18490	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
NRZ29_18495	COG0228	four-way junction DNA binding
NRZ29_18500	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
NRZ29_18505	COG4137	Cytochrome C assembly protein
NRZ29_18510	COG4536	flavin adenine dinucleotide binding
NRZ29_18520	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
NRZ29_18520	COG1017	nitric oxide dioxygenase activity
NRZ29_18525	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
NRZ29_18530	COG0039	L-malate dehydrogenase activity
NRZ29_18535	COG4160	amino acid transport
NRZ29_18540	COG4215	(ABC) transporter
NRZ29_18545	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
NRZ29_18550	COG1126	abc transporter atp-binding protein
NRZ29_18555	COG1438	arginine binding
NRZ29_18560	COG2837	iron assimilation
NRZ29_18565	COG3842	ATPase activity
NRZ29_18575	COG1840	ABC-type Fe3 transport system, periplasmic component
NRZ29_18580	COG0347	Belongs to the P(II) protein family
NRZ29_18595	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
NRZ29_18600	COG0583	DNA-binding transcription factor activity
NRZ29_18615	COG1929	Belongs to the glycerate kinase type-1 family
NRZ29_18620	COG2610	gluconate transmembrane transporter activity
NRZ29_18625	COG3835	regulator
NRZ29_18630	COG3112	Uncharacterised protein family (UPF0231)
NRZ29_18645	COG0840	transmembrane signaling receptor activity
NRZ29_18665	COG0513	Belongs to the DEAD box helicase family
NRZ29_18705	COG1448	Aminotransferase
NRZ29_18720	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
NRZ29_18725	COG1328	CTP reductase activity
NRZ29_18745	COG0793	Belongs to the peptidase S41A family
NRZ29_18745	COG4946	Tricorn protease homolog
NRZ29_18780	COG3397	chitin binding
NRZ29_18785	COG0583	DNA-binding transcription factor activity
NRZ29_18790	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
NRZ29_18795	COG4208	sulfate ABC transporter
NRZ29_18800	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
NRZ29_18810	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
NRZ29_18815	COG3174	membrane
NRZ29_18820	COG0110	maltose O-acetyltransferase activity
NRZ29_18840	COG1752	Esterase of the alpha-beta hydrolase superfamily
NRZ29_18845	COG0165	Argininosuccinate lyase
NRZ29_18850	COG0137	argininosuccinate synthase activity
NRZ29_18860	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
NRZ29_18865	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
NRZ29_18875	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
NRZ29_18880	COG0527	aspartate kinase activity
NRZ29_18880	COG0460	homoserine dehydrogenase
NRZ29_18885	COG0626	cystathionine gamma-synthase activity
NRZ29_18895	COG2207	Transcriptional regulator
NRZ29_18895	COG3708	Transcriptional regulator
NRZ29_18900	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NRZ29_18905	COG0814	amino acid
NRZ29_18910	COG1218	3'(2'),5'-bisphosphate nucleotidase
NRZ29_18915	COG0494	nUDIX hydrolase
NRZ29_18920	COG1011	Hydrolase
NRZ29_18925	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
NRZ29_18940	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
NRZ29_18950	COG3156	type II secretion system protein K
NRZ29_18955	COG4795	General secretion pathway protein
NRZ29_18960	COG2165	general secretion pathway protein
NRZ29_18975	COG2165	general secretion pathway protein
NRZ29_18980	COG1459	type II secretion system
NRZ29_18985	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
NRZ29_18995	COG3031	protein transport across the cell outer membrane
NRZ29_19005	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
NRZ29_19010	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
NRZ29_19030	COG0456	acetyltransferase
NRZ29_19035	COG3133	Outer membrane lipoprotein
NRZ29_19050	COG2771	luxR family
NRZ29_19055	COG3916	Acyl-homoserine-lactone synthase
NRZ29_19065	COG4776	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction
NRZ29_19070	COG1309	transcriptional regulator
NRZ29_19080	COG2213	PTS system mannitol-specific
NRZ29_19080	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
NRZ29_19085	COG0246	Mannitol dehydrogenase
NRZ29_19090	COG3722	fumarate hydratase activity
NRZ29_19095	COG3263	regulation of cellular component size
NRZ29_19120	COG1671	Belongs to the UPF0178 family
NRZ29_19135	COG1988	membrane-bound metal-dependent
NRZ29_19140	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
NRZ29_19145	COG0513	Belongs to the DEAD box helicase family
NRZ29_19170	COG1575	Belongs to the MenA family. Type 1 subfamily
NRZ29_19175	COG1169	isochorismate synthase
NRZ29_19180	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
NRZ29_19185	COG0596	Alpha beta hydrolase
NRZ29_19190	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
NRZ29_19195	COG1441	menaquinone biosynthetic process
NRZ29_19200	COG0318	PFAM AMP-dependent synthetase and ligase
NRZ29_19215	COG3539	Fimbrial protein
NRZ29_19225	COG3188	usher protein
NRZ29_19235	COG3539	Fimbrial protein
NRZ29_19245	COG3291	Pkd domain containing protein
NRZ29_19250	COG2949	membrane
NRZ29_19255	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
NRZ29_19265	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
NRZ29_19270	COG5380	lipid catabolic process
NRZ29_19285	COG4533	DNA binding
NRZ29_19295	COG2873	o-acetylhomoserine
NRZ29_19305	COG1979	alcohol dehydrogenase
NRZ29_19325	COG4221	oxidoreductase activity
NRZ29_19345	COG1285	pathogenesis
NRZ29_19365	COG1368	sulfuric ester hydrolase activity
NRZ29_19370	COG1522	sequence-specific DNA binding
NRZ29_19380	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
NRZ29_19385	COG1418	mRNA catabolic process
NRZ29_19390	COG1058	Belongs to the CinA family
NRZ29_19390	COG1546	Belongs to the CinA family
NRZ29_19400	COG0561	phosphatase activity
NRZ29_19405	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
NRZ29_19425	COG1011	Hydrolase
NRZ29_19440	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
NRZ29_19445	COG0019	diaminopimelate decarboxylase activity
NRZ29_19455	COG1965	Belongs to the frataxin family
NRZ29_19460	COG0400	carboxylic ester hydrolase activity
NRZ29_19465	COG3072	Adenylate cyclase
NRZ29_19470	COG0181	hydroxymethylbilane synthase activity
NRZ29_19480	COG2959	enzyme of heme biosynthesis
NRZ29_19495	COG1494	fructose-1,6-bisphosphatase
NRZ29_19535	COG1733	regulation of RNA biosynthetic process
NRZ29_19555	COG3932	Exopolysaccharide synthesis, ExoD
NRZ29_19560	COG0814	amino acid
NRZ29_19565	COG3706	GGDEF domain
NRZ29_19585	COG3417	Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1B (PBP1b)
NRZ29_19600	COG1943	Transposase
NRZ29_19605	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
NRZ29_19610	COG2022	thiamine diphosphate biosynthetic process
NRZ29_19620	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
NRZ29_19630	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
NRZ29_19650	COG0745	RESPONSE REGULATOR receiver
NRZ29_19655	COG0642	Histidine kinase
NRZ29_19665	COG0189	ligase activity
NRZ29_19690	COG1639	'signal transduction protein
NRZ29_19700	COG2321	neutral zinc metallopeptidase
NRZ29_19705	COG3700	Belongs to the class B bacterial acid phosphatase family
NRZ29_19725	COG1366	Belongs to the anti-sigma-factor antagonist family
NRZ29_19730	COG2172	sigma factor antagonist activity
NRZ29_19735	COG0784	Response regulator, receiver
NRZ29_19735	COG2205	protein histidine kinase activity
NRZ29_19735	COG5002	protein histidine kinase activity
NRZ29_19740	COG3437	response regulator, receiver
NRZ29_19750	COG0477	Major facilitator Superfamily
NRZ29_19770	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
NRZ29_19775	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
NRZ29_19775	COG1263	PTS System
NRZ29_19795	COG0312	modulator of DNA gyrase
NRZ29_19800	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
NRZ29_19815	COG3164	Protein of unknown function
NRZ29_19820	COG1530	ribonuclease E activity
NRZ29_19825	COG0424	maF-like protein
NRZ29_19830	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
NRZ29_19835	COG1792	Involved in formation and maintenance of cell shape
NRZ29_19840	COG1077	Cell shape determining protein MreB Mrl
NRZ29_19875	COG2165	general secretion pathway protein
NRZ29_19885	COG1459	type II secretion system
NRZ29_19890	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
NRZ29_19935	COG2200	EAL domain
NRZ29_19935	COG2199	diguanylate cyclase activity
NRZ29_19940	COG2200	EAL domain
NRZ29_19945	COG0387	Pfam Sodium calcium exchanger
NRZ29_19950	COG2986	histidine ammonia-lyase
NRZ29_19955	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
NRZ29_19960	COG0010	Belongs to the arginase family
NRZ29_19965	COG1228	amidohydrolase
NRZ29_19970	COG2188	Transcriptional regulator
NRZ29_19975	COG0288	reversible hydration of carbon dioxide
NRZ29_19985	COG2177	Part of the ABC transporter FtsEX involved in
NRZ29_19990	COG2884	Cell division ATP-binding protein ftsE
NRZ29_19995	COG0552	protein localization to endoplasmic reticulum
NRZ29_20000	COG0742	ribosomal rna small subunit methyltransferase
NRZ29_20025	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
NRZ29_20035	COG0741	lytic transglycosylase activity
NRZ29_20045	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
NRZ29_20055	COG2095	MarC family integral membrane protein
NRZ29_20065	COG1301	dicarboxylic acid transport
NRZ29_20090	COG3714	YhhN family
NRZ29_20115	COG1770	oligopeptidase
NRZ29_20130	COG4221	oxidoreductase activity
NRZ29_20135	COG0583	DNA-binding transcription factor activity
NRZ29_20140	COG2249	NAD(P)H dehydrogenase (quinone) activity
NRZ29_20185	COG0203	ribosomal protein L17
NRZ29_20190	COG0202	RNA polymerase activity
NRZ29_20195	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
NRZ29_20200	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
NRZ29_20205	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
NRZ29_20210	COG0257	Belongs to the bacterial ribosomal protein bL36 family
NRZ29_20215	COG0201	protein transport
NRZ29_20220	COG0200	Binds to the 23S rRNA
NRZ29_20225	COG1841	ribosomal large subunit assembly
NRZ29_20230	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
NRZ29_20235	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
NRZ29_20240	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
NRZ29_20245	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
NRZ29_20250	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
NRZ29_20255	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
NRZ29_20260	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
NRZ29_20265	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
NRZ29_20270	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
NRZ29_20275	COG0255	Belongs to the universal ribosomal protein uL29 family
NRZ29_20280	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
NRZ29_20285	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
NRZ29_20290	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
NRZ29_20295	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
NRZ29_20300	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
NRZ29_20305	COG0089	rRNA binding
NRZ29_20310	COG0088	Forms part of the polypeptide exit tunnel
NRZ29_20315	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
NRZ29_20320	COG0051	transcription antitermination factor activity, RNA binding
NRZ29_20340	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
NRZ29_20345	COG2183	response to ionizing radiation
NRZ29_20365	COG0596	Alpha beta hydrolase
NRZ29_20370	COG1040	competence protein
NRZ29_20375	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
NRZ29_20375	COG0316	Belongs to the HesB IscA family
NRZ29_20380	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
NRZ29_20385	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
NRZ29_20390	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
NRZ29_20395	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
NRZ29_20400	COG4942	peptidase
NRZ29_20410	COG1609	Transcriptional regulator
NRZ29_20415	COG0800	Aldolase
NRZ29_20420	COG0129	dihydroxy-acid dehydratase activity
NRZ29_20425	COG3265	gluconokinase activity
NRZ29_20430	COG2610	gluconate transmembrane transporter activity
NRZ29_20435	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
NRZ29_20440	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
NRZ29_20450	COG0456	acetyltransferase
NRZ29_20460	COG1490	D-aminoacyl-tRNA deacylase activity
NRZ29_20465	COG1295	ribonuclease BN
NRZ29_20470	COG1217	gtp-binding protein TYPA
NRZ29_20475	COG0174	glutamine synthetase
NRZ29_20485	COG3852	Histidine kinase
NRZ29_20490	COG2204	response regulator
NRZ29_20495	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
NRZ29_20500	COG0635	Involved in the biosynthesis of porphyrin-containing compound
NRZ29_20510	COG3078	GTPase activator activity
NRZ29_20520	COG0218	Necessary for normal cell division and for the maintenance of normal septation
NRZ29_20530	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
NRZ29_20535	COG0408	coproporphyrinogen oxidase activity
NRZ29_20540	COG0009	L-threonylcarbamoyladenylate synthase
NRZ29_20550	COG0551	DNA topoisomerase type I activity
NRZ29_20555	COG2922	Belongs to the Smg family
NRZ29_20560	COG0758	DNA mediated transformation
NRZ29_20570	COG0242	peptide deformylase activity
NRZ29_20575	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
NRZ29_20580	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
NRZ29_20580	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
NRZ29_20585	COG0569	domain protein
NRZ29_20590	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
NRZ29_20595	COG1322	Protein conserved in bacteria
NRZ29_20615	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
NRZ29_20620	COG0686	Belongs to the AlaDH PNT family
NRZ29_20625	COG0518	GMP synthase (glutamine-hydrolyzing) activity
NRZ29_20625	COG0519	Catalyzes the synthesis of GMP from XMP
NRZ29_20635	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
NRZ29_20640	COG1396	sequence-specific DNA binding
NRZ29_20645	COG1012	belongs to the aldehyde dehydrogenase family
NRZ29_20655	COG2962	Rard protein
NRZ29_20665	COG1280	lysine exporter protein (LysE YggA)
NRZ29_20675	COG2391	methyltransferase activity
NRZ29_20710	COG3161	chorismate lyase activity
NRZ29_20735	COG0583	DNA-binding transcription factor activity
NRZ29_20740	COG1943	Transposase
NRZ29_20755	COG0210	DNA helicase
NRZ29_20760	COG1744	ABC transporter substrate-binding protein PnrA-like
NRZ29_20765	COG3845	ABC transporter
NRZ29_20770	COG4603	Belongs to the binding-protein-dependent transport system permease family
NRZ29_20775	COG1079	Belongs to the binding-protein-dependent transport system permease family
NRZ29_20780	COG0583	DNA-binding transcription factor activity
NRZ29_20800	COG1262	PFAM Formylglycine-generating sulfatase enzyme
NRZ29_20805	COG0385	Bile acid
NRZ29_20810	COG0531	amino acid
NRZ29_20815	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NRZ29_20820	COG0531	amino acid
NRZ29_20825	COG2731	YhcH YjgK YiaL family protein
NRZ29_20830	COG3250	beta-galactosidase activity
NRZ29_20835	COG1609	Transcriptional regulator
NRZ29_20870	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
NRZ29_20875	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
NRZ29_20875	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
NRZ29_20880	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
NRZ29_20885	COG3074	FtsZ-dependent cytokinesis
NRZ29_20895	COG1045	serine acetyltransferase
NRZ29_20905	COG0745	RESPONSE REGULATOR receiver
NRZ29_20910	COG2205	protein histidine kinase activity
NRZ29_20915	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
NRZ29_20920	COG0534	Mate efflux family protein
NRZ29_20935	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
NRZ29_20940	COG2937	Belongs to the GPAT DAPAT family
NRZ29_20945	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
NRZ29_20950	COG3161	chorismate lyase activity
NRZ29_20955	COG1580	Controls the rotational direction of flagella during chemotaxis
NRZ29_20975	COG0604	alcohol dehydrogenase
NRZ29_20980	COG1609	Transcriptional regulator
NRZ29_21000	COG1519	Transferase
NRZ29_21005	COG0859	PFAM glycosyl transferase family 9
NRZ29_21010	COG0463	Glycosyl transferase, family 2
NRZ29_21015	COG0859	PFAM glycosyl transferase family 9
NRZ29_21020	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
NRZ29_21025	COG2990	Protein conserved in bacteria
NRZ29_21030	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
NRZ29_21040	COG0267	Belongs to the bacterial ribosomal protein bL33 family
NRZ29_21045	COG0227	Belongs to the bacterial ribosomal protein bL28 family
NRZ29_21050	COG2003	Belongs to the UPF0758 family
NRZ29_21055	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
NRZ29_21060	COG0756	dUTP diphosphatase activity
NRZ29_21065	COG1309	transcriptional regulator
NRZ29_21070	COG0668	transmembrane transport
NRZ29_21080	COG0166	Belongs to the GPI family
NRZ29_21085	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
NRZ29_21090	COG0583	DNA-binding transcription factor activity
NRZ29_21105	COG0045	succinate-CoA ligase (ADP-forming) activity
NRZ29_21105	COG1042	CoA-binding domain protein
NRZ29_21105	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
NRZ29_21130	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
NRZ29_21135	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
NRZ29_21140	COG1739	Uncharacterized protein family UPF0029
NRZ29_21145	COG0006	proline dipeptidase activity
NRZ29_21150	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
NRZ29_21155	COG1024	Enoyl-CoA hydratase
NRZ29_21155	COG1250	3-hydroxyacyl-CoA dehydrogenase
NRZ29_21160	COG0183	Belongs to the thiolase family
NRZ29_21185	COG0425	Belongs to the sulfur carrier protein TusA family
NRZ29_21190	COG0251	oxidation-reduction process
NRZ29_21195	COG2885	chlorophyll binding
NRZ29_21205	COG2818	Glycosylase
NRZ29_21210	COG0752	glycyl-tRNA synthetase alpha subunit
NRZ29_21215	COG0751	glycine-tRNA ligase activity
NRZ29_21225	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
NRZ29_21245	COG0814	amino acid
NRZ29_21250	COG0348	domain, Protein
NRZ29_21255	COG2188	Transcriptional regulator
NRZ29_21270	COG1609	Transcriptional regulator
NRZ29_21310	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
NRZ29_21335	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
NRZ29_21350	COG3118	belongs to the thioredoxin family
NRZ29_21355	COG0513	Belongs to the DEAD box helicase family
NRZ29_21360	COG0248	Ppx GppA phosphatase
NRZ29_21370	COG0742	ribosomal rna small subunit methyltransferase
NRZ29_21375	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
NRZ29_21405	COG0084	hydrolase, TatD family'
NRZ29_21410	COG0805	protein transport
NRZ29_21415	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
NRZ29_21425	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
NRZ29_21430	COG3165	ubiquinone biosynthetic process from chorismate
NRZ29_21440	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
NRZ29_21445	COG0402	S-adenosylhomocysteine deaminase activity
NRZ29_21490	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
NRZ29_21495	COG0848	biopolymer transport protein
NRZ29_21500	COG0811	peptide transport
NRZ29_21505	COG0811	peptide transport
NRZ29_21515	COG2771	luxR family
NRZ29_21520	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
NRZ29_21525	COG1349	DNA-binding transcription factor activity
NRZ29_21530	COG0745	RESPONSE REGULATOR receiver
NRZ29_21535	COG2205	protein histidine kinase activity
NRZ29_21545	COG4452	Inner membrane protein CreD
NRZ29_21550	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
NRZ29_21555	COG0355	proton-transporting ATP synthase activity, rotational mechanism
NRZ29_21560	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
NRZ29_21565	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
NRZ29_21570	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
NRZ29_21575	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
NRZ29_21580	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
NRZ29_21590	COG0356	it plays a direct role in the translocation of protons across the membrane
NRZ29_21600	COG1475	DNA binding
NRZ29_21605	COG1192	Involved in chromosome partitioning
NRZ29_21610	COG0357	Ribosomal RNA small subunit methyltransferase G
NRZ29_21615	COG0445	tRNA wobble uridine modification
NRZ29_21620	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
NRZ29_21625	COG4774	siderophore transport
NRZ29_21630	COG4615	Cyclic peptide transporter
NRZ29_21635	COG1120	ATPase activity
NRZ29_21650	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
NRZ29_21655	COG0706	membrane insertase activity
NRZ29_21660	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
NRZ29_21665	COG0594	ribonuclease P activity
NRZ29_21670	COG0230	Belongs to the bacterial ribosomal protein bL34 family
NRZ29_21675	COG1126	abc transporter atp-binding protein