locus-tag	class	description
A9258_00005	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
A9258_00010	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
A9258_00015	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
A9258_00020	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
A9258_00030	ENOG4105D29	Helix-turn-helix type 11 domain protein
A9258_00035	ENOG4108ZNX	Heat shock protein
A9258_00040	ENOG4108ZNX	Heat shock protein
A9258_00045	ENOG4105JKW	Valine--pyruvate aminotransferase
A9258_00060	ENOG4105C2C	drug resistance transporter, Bcr CflA
A9258_00065	ENOG4105EEX	Two component transcriptional regulator (Winged helix family
A9258_00070	ENOG4105C08	Histidine kinase
A9258_00080	ENOG4105C8X	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity)
A9258_00085	ENOG4105D9K	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity)
A9258_00100	ENOG4105CAF	HipA N-terminal domain protein
A9258_00140	ENOG4105DC8	reductase
A9258_00145	ENOG4105BZU	Histidine kinase
A9258_00150	ENOG4105BZS	acriflavin resistance protein
A9258_00155	ENOG410624X	efflux transporter, rnd family, mfp subunit
A9258_00160	ENOG4105Y7M	Transcriptional regulator, TetR family
A9258_00190	ENOG4105CA9	Pyruvate kinase
A9258_00195	ENOG4105CXY	transporter
A9258_00200	ENOG4106JDA	Phosphoglycerate transport regulatory protein PGTC
A9258_00210	ENOG4107TXD	phosphoglycerate transport system transcriptional regulatory protein pgta
A9258_00220	ENOG4105DQF	Hydrolase
A9258_00225	ENOG4108EUD	Lysophospholipase
A9258_00235	ENOG4105FE8	tRNA (Guanosine-2'-O-)-methyltransferase
A9258_00240	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
A9258_00245	ENOG4105VFG	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity)
A9258_00255	ENOG4105DKP	glycosyl transferase, family 9
A9258_00260	ENOG4108W7E	Catalyzes the ATP-dependent phosphorylation of the 3- deoxy-D-manno-octulosonic acid (Kdo) residue in Kdo-lipid IV(A) at the 4-OH position (By similarity)
A9258_00270	ENOG4105EMK	carboxylate amino acid amine transporter
A9258_00295	ENOG4108M6U	Universal stress protein A
A9258_00300	ENOG4105RKW	reductase (By
A9258_00305	ENOG4105BZU	Histidine kinase
A9258_00310	ENOG41090A1	ferritin
A9258_00315	ENOG4105CBX	hi0933 family
A9258_00320	ENOG4105EU0	Major facilitator Superfamily
A9258_00340	ENOG4108N3D	putative enzyme
A9258_00345	ENOG4108NN8	Fimbrial protein
A9258_00350	ENOG4108GWT	fimbrillin MatB
A9258_00355	ENOG4107ZHV	Transcriptional regulator
A9258_00360	ENOG4105BZU	Histidine kinase
A9258_00370	ENOG4108HRK	Histidine kinase
A9258_00375	ENOG4105DY9	regulatoR
A9258_00380	ENOG4105FCD	Major Facilitator
A9258_00385	ENOG4105CY8	phosphoribosylaminoimidazole carboxylase atpase subunit
A9258_00390	ENOG4108UM6	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity)
A9258_00405	ENOG41063Z6	transcriptional regulator, lysR family
A9258_00410	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
A9258_00415	ENOG4105F03	Provides the (R)-glutamate required for cell wall biosynthesis (By similarity)
A9258_00450	ENOG4105CUZ	uba thif-type nad fad binding protein
A9258_00455	ENOG4105P9C	Participates in cysteine desulfuration mediated by SufS. Cysteine desulfuration mobilizes sulfur from L-cysteine to yield L-alanine and constitutes an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules. Functions as a sulfur acceptor for SufS, by mediating the direct transfer of the sulfur atom from the S-sulfanylcysteine of SufS, an intermediate product of cysteine desulfuration process (By similarity)
A9258_00460	ENOG4105C9B	Cysteine desulfurase
A9258_00465	ENOG4105C4R	Atp-dependent dna helicase
A9258_00470	ENOG4105BZU	Histidine kinase
A9258_00475	ENOG4105MPD	Cytochrome
A9258_00480	ENOG4105CPQ	Dehydrogenase
A9258_00485	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
A9258_00490	ENOG41062JF	Transcriptional regulator
A9258_00495	ENOG4105CUI	Catalyzes the interconversion between ADP-D-glycero- beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose (By similarity)
A9258_00510	ENOG4105W1T	Glycosyl Transferase
A9258_00530	ENOG4105DSJ	YicC domain protein
A9258_00535	ENOG4105ED0	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates (By similarity)
A9258_00540	ENOG4107QP2	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
A9258_00560	ENOG4105PC1	Conserved Protein
A9258_00570	ENOG4105E27	serine threonine protein kinase
A9258_00575	ENOG4108Z33	Thiol disulfide Interchange Protein
A9258_00580	ENOG4105S7S	phosphonate abc transporter
A9258_00585	ENOG4108VA1	ABC transporter
A9258_00590	ENOG4105EHI	Phosphonate ABC transporter, periplasmic
A9258_00595	ENOG4107RH7	Nicotinate phosphoribosyltransferase
A9258_00600	ENOG4108RWI	nicotinamidase
A9258_00610	ENOG4105EWC	Purine nucleoside phosphorylase
A9258_00615	ENOG4106HNH	Acyl-transferase
A9258_00620	ENOG4106HNH	Acyl-transferase
A9258_00625	ENOG4105C0P	Mg chelatase subunit ChlI
A9258_00635	ENOG4105P3Y	Acetolactate synthase 2 regulatory subunit
A9258_00640	ENOG4105CM2	brancheD-chain amino acid aminotransferase
A9258_00645	ENOG4105C01	Dihydroxy-acid dehydratase
A9258_00650	ENOG4105C7B	Threonine dehydratase
A9258_00655	ENOG4105UYK	outer membrane protein a
A9258_00665	ENOG4105C25	Primosomal protein n'
A9258_00670	ENOG4105VFB	Binds the 23S rRNA (By similarity)
A9258_00675	ENOG4105CGD	Nad-dependent epimerase dehydratase
A9258_00680	ENOG4105C6K	Malic enzyme
A9258_00690	ENOG4105JJR	Histidine kinase
A9258_00695	ENOG4107EXC	regulatoR
A9258_00700	ENOG4107R9T	Catalyzes the formation of 5-methyl-uridine at position 54 (m5U54) in all tRNAs (By similarity)
A9258_00715	ENOG4107R28	alpha amylase, catalytic region
A9258_00730	ENOG4105R8A	Heat shock protein
A9258_00735	ENOG4105C5I	Dehydrogenase
A9258_00740	ENOG4108RH0	Crea protein
A9258_00755	ENOG4108V7X	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
A9258_00760	ENOG4105CFQ	glutamine synthetase
A9258_00765	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
A9258_00775	ENOG4108HM4	ABC transporter
A9258_00780	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
A9258_00785	ENOG4105F38	ABC transporter, permease
A9258_00790	ENOG4105D38	putrescine abc transporter
A9258_00795	ENOG4108RPX	mosc domain containing protein
A9258_00815	ENOG4108VUY	thioesterase Superfamily protein
A9258_00820	ENOG4105C9U	ATP-dependent DNA helicase RecQ
A9258_00825	ENOG4105N7H	Cytochrome
A9258_00830	ENOG4105CNG	UPF0061 protein
A9258_00840	ENOG4105EX9	Membrane
A9258_00845	ENOG4108YYX	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. Modulates RNA-binding and helicase activities of the degradosome (By similarity)
A9258_00850	ENOG4108NVR	Methyl-accepting chemotaxis
A9258_00855	ENOG4105CJW	magnesium transporter
A9258_00860	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
A9258_00865	ENOG4107V9H	nitrite transporter
A9258_00870	ENOG4105WZK	nitrite reductase NADPH small subunit
A9258_00875	ENOG4107QZF	nitrite reductase NADPH large subunit
A9258_00890	ENOG4105C4N	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis (By similarity)
A9258_00895	ENOG4108R5P	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery (By similarity)
A9258_00905	ENOG4105C75	arginyL-tRNA synthetase
A9258_00915	ENOG4105K6V	RNA polymerase
A9258_00920	ENOG4108NIX	Factor ChrR
A9258_00925	ENOG4105DWR	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity)
A9258_00930	ENOG4105CPC	Aldo Keto reductase
A9258_00935	ENOG4105ENN	converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose (By similarity)
A9258_00940	ENOG4105CRD	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P) (By similarity)
A9258_00945	ENOG4105F0Z	galactose-1-phosphate uridylyltransferase
A9258_00950	ENOG4105CMR	udp-glucose 4-epimerase
A9258_00955	ENOG41060NJ	transcriptional regulator
A9258_00960	ENOG4105CNT	hydrolase family 2
A9258_00970	ENOG4105C2J	ABC transporter
A9258_00975	ENOG4107SDZ	Galactoside transport system permease protein mglC
A9258_00980	ENOG4105C8Q	Methyl-accepting chemotaxis
A9258_01000	ENOG4105C5B	carbamate kinase
A9258_01005	ENOG4105DBV	ornithine carbamoyltransferase
A9258_01010	ENOG4105CSX	c4-dicarboxylate anaerobic carrier
A9258_01015	ENOG410682Y	Regulates arginine biosynthesis genes (By similarity)
A9258_01020	ENOG4108R9M	Involved in allosteric regulation of aspartate carbamoyltransferase (By similarity)
A9258_01025	ENOG4105CXT	aspartate transcarbamylase
A9258_01040	ENOG4105DJ4	phosphatidylserine decarboxylase
A9258_01045	ENOG4105C8Q	Methyl-accepting chemotaxis
A9258_01055	ENOG4105CF7	AraC family transcriptional regulator
A9258_01060	ENOG4108I6A	alcohol dehydrogenase
A9258_01065	ENOG4108IIE	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
A9258_01070	ENOG4105C15	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
A9258_01080	ENOG4105WWK	YheO domain protein
A9258_01085	ENOG4105CEM	UPF0597 protein
A9258_01095	ENOG4107QMW	pyridine nucleotide-disulfide oxidoreductase
A9258_01100	ENOG4106SNF	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
A9258_01105	ENOG4105C34	Pseudouridine synthase
A9258_01110	ENOG4105DBW	Multi-copper polyphenol oxidoreductase laccase
A9258_01115	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
A9258_01120	ENOG4107T8T	UPF0173 metal-dependent hydrolase
A9258_01125	ENOG4105CU9	asparagine synthetase A
A9258_01130	ENOG4108VVK	transcriptional Regulator, AsnC
A9258_01145	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
A9258_01150	ENOG410642E	Short chain dehydrogenase
A9258_01160	ENOG4107WP9	Histidine kinase
A9258_01170	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
A9258_01175	ENOG4108UQ5	membrane protein YcdZ
A9258_01185	ENOG4105DQ2	Is probably involved in the electron transfer between its heme and the molybdenum cofactor of the reductase catalytic subunit YedY (By similarity)
A9258_01200	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
A9258_01205	ENOG4105IFJ	Histidine kinase
A9258_01215	ENOG4107QY8	reductase
A9258_01220	ENOG4105CUW	cytochrome C-TYPE protein
A9258_01225	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
A9258_01240	ENOG4105E7U	AraC family transcriptional regulator
A9258_01250	ENOG4107ZYR	domain protein
A9258_01255	ENOG4105D4A	Cell wall formation (By similarity)
A9258_01260	ENOG4105HJX	Biotin- acetyl-CoA-carboxylase ligase
A9258_01265	ENOG4105CS9	pantothenic acid kinase
A9258_01280	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
A9258_01290	ENOG4105PM1	preprotein translocase subunit SecE
A9258_01295	ENOG4105E5V	Participates in transcription elongation, termination and antitermination (By similarity)
A9258_01300	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
A9258_01305	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
A9258_01310	ENOG4108VZM	50s ribosomal protein L10
A9258_01315	ENOG4105KBC	Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity)
A9258_01320	ENOG4108IIJ	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
A9258_01325	ENOG4105D27	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
A9258_01335	ENOG4105WWK	YheO domain protein
A9258_01340	ENOG4105KME	endoribonuclease L-psp
A9258_01350	ENOG4108ZKU	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions (By similarity)
A9258_01355	ENOG4105YKK	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions (By similarity)
A9258_01365	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
A9258_01370	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
A9258_01375	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
A9258_01380	ENOG4108ZI0	d,d-heptose 1,7-bisphosphate phosphatase
A9258_01415	ENOG4105C7N	Xanthine uracil vitamin C permease
A9258_01420	ENOG4105CMT	Dihydroxyacetone kinase
A9258_01425	ENOG4108UTZ	Dihydroxyacetone kinase
A9258_01440	ENOG4108JU9	GAF modulated sigma54 specific transcriptional regulator Fis family
A9258_01445	ENOG4105ETT	transcriptional Regulator, LysR family
A9258_01450	ENOG4105DWY	Agmatine deiminase
A9258_01455	ENOG4105EMU	Dehydrogenase
A9258_01460	ENOG4105IPI	Membrane
A9258_01490	ENOG4105CH6	catalase
A9258_01495	ENOG4105WCN	acetyltransferase
A9258_01515	ENOG4105BZU	Histidine kinase
A9258_01525	ENOG4108IJ6	ABC transporter
A9258_01535	ENOG4105E4X	binding-protein-dependent transport systems inner membrane Component
A9258_01560	ENOG4105CWB	LysR family transcriptional Regulator
A9258_01570	ENOG4105C2I	pirin domain protein
A9258_01575	ENOG4108VBZ	doxx family
A9258_01580	ENOG4105DSY	exodeoxyribonuclease V, gamma
A9258_01585	ENOG4107QKA	exodeoxyribonuclease V beta
A9258_01590	ENOG4107QYX	exodeoxyribonuclease v alpha
A9258_01600	ENOG4105KHA	Glyoxalase Bleomycin resistance protein (Dioxygenase
A9258_01635	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
A9258_01640	ENOG4105E0F	Histidine kinase
A9258_01650	ENOG4105D05	Receptor
A9258_01655	ENOG4105VEQ	Cold shock protein
A9258_01665	ENOG41076HS	cation diffusion facilitator family transporter
A9258_01675	ENOG4108UUM	single-stranded DNA-binding protein
A9258_01680	ENOG41086KC	Transcriptional regulator
A9258_01685	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
A9258_01695	ENOG4105EIF	outer membrane protein W
A9258_01700	ENOG4105C8Q	Methyl-accepting chemotaxis
A9258_01715	ENOG4105SYT	Methylenetetrahydrofolate reductase
A9258_01725	ENOG4105DKK	Benzoate
A9258_01730	ENOG4108JCI	Transcriptional regulator
A9258_01760	ENOG41090HJ	UPF0265 protein
A9258_01770	ENOG4105N42	UPF0307 protein
A9258_01775	ENOG4105CMS	peptidase U62, modulator of DNA gyrase
A9258_01780	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
A9258_01785	ENOG4105VFK	BolA family
A9258_01795	ENOG4105E3I	toluene tolerance
A9258_01800	ENOG4107PE3	Mammalian cell entry related domain protein
A9258_01805	ENOG4105CY3	ABC transporter, permease
A9258_01810	ENOG4105DHJ	ABC, transporter
A9258_01815	ENOG4105C2X	Arabinose 5-phosphate isomerase
A9258_01820	ENOG4108Z4R	3-deoxy-d-manno-octulosonate 8-phosphate phosphatase
A9258_01825	ENOG4108P1K	Required for the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane (By similarity)
A9258_01830	ENOG4105WI0	lipopolysaccharide transport periplasmic protein lptA
A9258_01835	ENOG4108IUZ	ABC transporter
A9258_01840	ENOG4105DTW	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
A9258_01845	ENOG41080QH	sigma 54 modulation protein ribosomal protein S30EA
A9258_01850	ENOG4107RM2	PTS IIA-like nitrogen-regulatory protein PtsN
A9258_01855	ENOG4105C21	Displays ATPase and GTPase activities (By similarity)
A9258_01860	ENOG41080Z8	PHOSPHOCARRIER protein
A9258_01865	ENOG4105EMD	TRANSCRIPTIONal
A9258_01880	ENOG41069H0	dihydroorotase EC 3.5.2.3
A9258_01910	ENOG4105C0H	protease
A9258_01915	ENOG4105C0H	protease
A9258_01925	ENOG4105D6Z	AFG1 family ATPase
A9258_01930	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
A9258_01935	ENOG4108UJD	30S ribosomal protein S9
A9258_01940	ENOG4108R5F	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
A9258_01945	ENOG4105DJ5	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
A9258_01950	ENOG4105EIX	cytochrome c1
A9258_01955	ENOG4107MKT	Stringent starvation protein a
A9258_01960	ENOG4105KB2	stringent starvation protein b
A9258_01965	ENOG4105W4M	Transport-associated protein
A9258_01970	ENOG4105F55	Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate (By similarity)
A9258_01975	ENOG41082RQ	UPF0102 protein
A9258_01980	ENOG4105E1C	Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1A (PBP1a) (By similarity)
A9258_01985	ENOG4105CU0	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity)
A9258_01995	ENOG4108V6E	Cell division protein mraZ
A9258_02000	ENOG4105CGJ	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity)
A9258_02005	ENOG41063Y6	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity)
A9258_02010	ENOG4105CJN	penicillin-binding protein
A9258_02015	ENOG4107EEN	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity)
A9258_02020	ENOG4108EQQ	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein (By similarity)
A9258_02025	ENOG4105CPY	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity)
A9258_02030	ENOG4105DMZ	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity)
A9258_02035	ENOG4105CNI	cell division protein FtsW
A9258_02040	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
A9258_02045	ENOG4105DFU	Cell wall formation (By similarity)
A9258_02050	ENOG4105K7E	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly (By similarity)
A9258_02055	ENOG4105CIT	This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity)
A9258_02060	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
A9258_02065	ENOG4105C7C	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
A9258_02075	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
A9258_02085	ENOG4105EJF	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity)
A9258_02090	ENOG41067SF	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase (By similarity)
A9258_02095	ENOG4105DHA	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity (By similarity)
A9258_02110	ENOG4105D7Q	type ii secretion system
A9258_02115	ENOG4107QHF	type ii secretion system protein e
A9258_02125	ENOG4105D18	nicotinate-nucleotide pyrophosphorylase
A9258_02140	ENOG41073TP	transcriptional regulator
A9258_02145	ENOG4105DAQ	Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) (By similarity)
A9258_02150	ENOG4107QSN	dihydrolipoamide acetyltransferase
A9258_02155	ENOG4107QN2	dihydrolipoyl dehydrogenase
A9258_02160	ENOG4105BZU	Histidine kinase
A9258_02170	ENOG4108N3W	hemolysin secretion protein
A9258_02175	ENOG4108N3W	hemolysin secretion protein
A9258_02180	ENOG4105D78	K07001 NTE family protein
A9258_02185	ENOG4107QIJ	Aconitate hydratase 2
A9258_02200	ENOG4105E82	cytochrome subunit of dehydrogenase
A9258_02210	ENOG4105CKI	cobalamin synthesis protein
A9258_02215	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
A9258_02225	ENOG4105K8U	2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
A9258_02230	ENOG4107ZVW	dihydroneopterin aldolase
A9258_02235	ENOG4105K7Z	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP (By similarity)
A9258_02275	ENOG4105DWD	nucleoside recognition domain protein
A9258_02280	ENOG4107R88	Chemotaxis protein (CheV)
A9258_02285	ENOG410904N	short-chain dehydrogenase reductase
A9258_02290	ENOG4105E0I	Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of tRNA(Met), by using acetyl-CoA as an acetyl donor and ATP (or GTP) (By similarity)
A9258_02305	ENOG4108UQY	Iron-storage protein
A9258_02315	ENOG4108Z5K	methylglyoxal synthase
A9258_02330	ENOG4105HDK	L-asparaginase
A9258_02345	ENOG4105D4X	repressor
A9258_02350	ENOG4105C5Y	PTS System
A9258_02355	ENOG4105CG3	alpha amylase, catalytic region
A9258_02360	ENOG4108UW5	maltose o-acetyltransferase
A9258_02370	ENOG4107AQZ	Membrane
A9258_02380	ENOG4105C26	Dehydrogenase
A9258_02385	ENOG4105NRK	Binding-protein-dependent transport systems, inner membrane component
A9258_02390	ENOG4105D81	ABC transporter, permease
A9258_02395	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
A9258_02400	ENOG4107TYH	extracellular solute-binding protein family 1
A9258_02405	ENOG4108M0I	Transcriptional regulator
A9258_02410	ENOG4105DFD	Na H antiporter
A9258_02450	ENOG4105CXW	Synthesizes alpha-1,4-glucan chains using ADP-glucose (By similarity)
A9258_02455	ENOG4107QQ4	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans (By similarity)
A9258_02460	ENOG4105D8J	Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle (By similarity)
A9258_02465	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
A9258_02480	ENOG4107VXZ	Hydrolase
A9258_02485	ENOG4105KW8	RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity)
A9258_02490	ENOG4105F1S	paraquat-inducible protein a
A9258_02495	ENOG4105DY2	Paraquat-inducible protein b
A9258_02500	ENOG4108Q2G	(LipO)protein
A9258_02505	ENOG4105UYK	outer membrane protein a
A9258_02520	ENOG4105H4F	exported protein
A9258_02530	ENOG4105KMG	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes (By similarity)
A9258_02535	ENOG4105CEN	a g-specific adenine glycosylase
A9258_02555	ENOG4105D4J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
A9258_02570	ENOG41067MG	lrgb family
A9258_02580	ENOG4105CMU	LysR family (Transcriptional regulator
A9258_02605	ENOG4108Z66	YbaK ebsC protein
A9258_02610	ENOG4105CJ3	phosphate transporter
A9258_02615	ENOG4107IX6	phosphate transport regulator
A9258_02630	ENOG4105D1S	lipid A biosynthesis
A9258_02635	ENOG4105DW0	Catalyzes the ADP transfer to D-glycero-D-manno-heptose 1-phosphate, yielding ADP-D,D-heptose (By similarity)
A9258_02640	ENOG4105DFG	type I secretion outer membrane protein
A9258_02645	ENOG41087AY	ADP-Ribose pyrophosphatase
A9258_02650	ENOG4108SX3	cytoplasmic protein
A9258_02655	ENOG41070EG	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes (By similarity)
A9258_02660	ENOG4105IPS	esterase
A9258_02680	ENOG4105Y49	secretion protein, HlyD family
A9258_02685	ENOG4105DSW	Fusaric acid resistance protein
A9258_02690	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
A9258_02695	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
A9258_02730	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
A9258_02735	ENOG4105N2G	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
A9258_02760	ENOG4107S7E	1-acyl-sn-glycerol-3-phosphate acyltransferase
A9258_02765	ENOG41087YS	Phage shock protein A
A9258_02780	ENOG41082IR	Excinuclease ABC C subunit domain protein
A9258_02790	ENOG4105FR1	rard protein
A9258_02795	ENOG4108RG0	uracil-dna glycosylase
A9258_02810	ENOG4105FAV	ABC, transporter
A9258_02815	ENOG4105FDK	ABC transporter
A9258_02820	ENOG4105NXV	High-affinity zinc uptake system protein
A9258_02840	ENOG4105DR5	peptidase
A9258_02850	ENOG4105R2J	Conserved Protein
A9258_02870	ENOG4105D86	that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity)
A9258_02875	ENOG4105DFP	Integrase
A9258_02895	ENOG4107TH8	cina domain protein
A9258_02900	ENOG4105C68	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity)
A9258_02910	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
A9258_02915	ENOG4105CFH	Aspartokinase
A9258_02920	ENOG4105VM8	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding (By similarity)
A9258_02955	ENOG41061WM	D-Alanyl-D-Alanine
A9258_02960	ENOG4106W5V	Membrane
A9258_02970	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
A9258_02975	ENOG4105MYG	DNA polymerase iii, chi subunit
A9258_02980	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
A9258_02985	ENOG4108M8S	permease YjgP YjgQ family protein
A9258_02990	ENOG4108K5H	permease YjgP YjgQ family protein
A9258_03005	ENOG4105DFP	Integrase
A9258_03020	ENOG4105XB7	anti-repressor protein
A9258_03045	ENOG4105BZU	Histidine kinase
A9258_03050	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
A9258_03060	ENOG4105EYA	deoxyribonuclease
A9258_03065	ENOG4105D9N	nucleoside
A9258_03075	ENOG4105FCI	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate (By similarity)
A9258_03080	ENOG4105CMW	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis (By similarity)
A9258_03085	ENOG4105CZG	Phosphotransfer between the C1 and C5 carbon atoms of pentose (By similarity)
A9258_03090	ENOG4105D3A	purine nucleoside phosphorylase DeoD-type
A9258_03095	ENOG4105BZU	Histidine kinase
A9258_03105	ENOG4105EAC	phosphoserine phosphatase
A9258_03120	ENOG4105DNJ	May play a role in the repair of endogenous alkylation damage (By similarity)
A9258_03130	ENOG4108ZVW	Anti-RNA polymerase sigma 70 factor
A9258_03135	ENOG4105K70	DNA-binding protein
A9258_03145	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
A9258_03165	ENOG4105CWM	branched-chain amino acid transport system II carrier protein
A9258_03170	ENOG4105CWM	branched-chain amino acid transport system II carrier protein
A9258_03175	ENOG4107S47	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC) (By similarity)
A9258_03180	ENOG4105C1J	atp-dependent rna helicase
A9258_03185	ENOG4105D1Q	UPF0246 protein
A9258_03190	ENOG4105CZX	twitching motility protein
A9258_03195	ENOG4105CZX	twitching motility protein
A9258_03200	ENOG4105DFA	alanine racemase domain protein
A9258_03205	ENOG4105II7	pyrroline-5-carboxylate reductase
A9258_03210	ENOG4108VIA	integral membrane protein
A9258_03215	ENOG4105VZ9	UPF0235 protein
A9258_03230	ENOG4107QSI	ABC, transporter
A9258_03240	ENOG4105EQK	-acetyltransferase
A9258_03245	ENOG4106WH9	Protein of unknown function (DUF2753)
A9258_03250	ENOG4105E39	Enoyl-CoA hydratase
A9258_03265	ENOG4108RZ4	Short-chain dehydrogenase reductase Sdr
A9258_03270	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
A9258_03275	ENOG4105C8Q	Methyl-accepting chemotaxis
A9258_03280	ENOG4105KA4	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity)
A9258_03285	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
A9258_03290	ENOG4105C4M	(Ubiquinol oxidase) subunit I
A9258_03295	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
A9258_03305	ENOG4105KJB	cyd operon protein YbgE
A9258_03310	ENOG4107YD3	Thioesterase
A9258_03315	ENOG4105E02	MotA TolQ exbB proton channel
A9258_03320	ENOG4105M8F	Biopolymer transport protein exbD tolR
A9258_03330	ENOG4107R6Y	Involved in the TonB-independent uptake of proteins (By similarity)
A9258_03335	ENOG4105KCK	Peptidoglycan-associated lipoprotein
A9258_03340	ENOG4105UFD	tol-pal system protein YbgF
A9258_03375	ENOG4105C8Q	Methyl-accepting chemotaxis
A9258_03380	ENOG4105D0I	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate (By similarity)
A9258_03385	ENOG4105DSB	aldose 1-epimerase
A9258_03395	ENOG4107RTM	4-alpha-glucanotransferase (EC 2.4.1.25)
A9258_03400	ENOG4105C9C	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity)
A9258_03410	ENOG4105E0X	reductase
A9258_03420	ENOG4105EJF	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity)
A9258_03425	ENOG4105CJH	Alcohol dehydrogenase zinc-binding domain protein
A9258_03430	ENOG4108ZHJ	Organic hydroperoxide resistance protein
A9258_03435	ENOG4105K56	Transcriptional regulator
A9258_03450	ENOG4105EW9	transcriptional regulator AsnC family
A9258_03465	ENOG4108K4B	hydrolase
A9258_03480	ENOG4105C8J	)-transporter
A9258_03490	ENOG4105C8J	)-transporter
A9258_03515	ENOG4107SQD	Transcriptional regulator, GntR family
A9258_03535	ENOG4105E3B	Multicopper oxidase
A9258_03545	ENOG4105XEP	YhcH YjgK YiaL family protein
A9258_03555	ENOG4105CUY	Mechanosensitive ion channel
A9258_03560	ENOG4107N1Q	ErfK YbiS YcfS YnhG family protein
A9258_03565	ENOG4105CK7	Sodium proline symporter
A9258_03600	ENOG4105EQ2	LysR family Transcriptional regulator
A9258_03605	ENOG4105D6S	protein involved in catabolism of external DNA
A9258_03615	ENOG4105C5H	ABC transporter
A9258_03620	ENOG4105C2X	Arabinose 5-phosphate isomerase
A9258_03625	ENOG4105G5H	Membrane
A9258_03630	ENOG4107QX8	SPFH domain, Band 7 family protein
A9258_03635	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
A9258_03640	ENOG4105C11	sulfate adenylyltransferase), subunit 2
A9258_03645	ENOG4105C3T	may be the GTPase, regulating ATP sulfurylase activity (By similarity)
A9258_03655	ENOG4108I67	Catalyzes the synthesis of activated sulfate (By similarity)
A9258_03675	ENOG4107RHT	methyl-accepting chemotaxis sensory transducer with Pas Pac sensor
A9258_03710	ENOG4108UUE	Transcriptional regulator
A9258_03725	ENOG4105F0N	pyrophosphate phospho-hydrolase
A9258_03730	ENOG4105DFU	Cell wall formation (By similarity)
A9258_03735	ENOG4108UMA	3-octaprenyl-4-hydroxybenzoate carboxy-lyase
A9258_03740	ENOG410630P	Transcriptional regulator
A9258_03745	ENOG4108UGV	hypoxanthine phosphoribosyltransferase
A9258_03750	ENOG4105DA5	(ABC) transporter
A9258_03755	ENOG4105E3A	(ABC) transporter
A9258_03760	ENOG4105DCU	2-hydroxyglutaryl-CoA dehydratase
A9258_03765	ENOG4105CIZ	coA-substrate-specific enzyme activase
A9258_03785	ENOG4108IAA	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate (By similarity)
A9258_03790	ENOG4105CCG	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is tranferred onto alpha-ketoisovalerate to form ketopantoate (By similarity)
A9258_03795	ENOG4105K8U	2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
A9258_03800	ENOG4105DJ0	Poly(A) Polymerase
A9258_03805	ENOG4106F3G	Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon (By similarity)
A9258_03810	ENOG4108V7X	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
A9258_03815	ENOG4105PW4	Sugar fermentation stimulation protein homolog
A9258_03825	ENOG4105CQ7	ATP-dependent helicase
A9258_03830	ENOG4105BZ4	penicillin-binding protein
A9258_03835	ENOG4108YZK	glyoxalase bleomycin resistance protein dioxygenase
A9258_03840	ENOG4108ZBZ	Catalyzes the excretion of spermidine (By similarity)
A9258_03845	ENOG41090TI	Catalyzes the excretion of spermidine (By similarity)
A9258_03855	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
A9258_03865	ENOG41076MN	Phosphoesterase, PA-phosphatase related
A9258_03880	ENOG4105CDM	Glutamate-1-semialdehyde aminotransferase
A9258_03885	ENOG4105CMQ	Chloride channel
A9258_03895	ENOG4108YX9	iron--sulfur cluster insertion protein erpA
A9258_03920	ENOG4108NIW	Leucine export protein LeuE
A9258_03925	ENOG4105VY0	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters (By similarity)
A9258_03930	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
A9258_03940	ENOG4107V40	secretion protein, HlyD family
A9258_03970	ENOG4105I93	response regulator
A9258_03975	ENOG4105DUX	Transporter
A9258_03980	ENOG4105C3Y	UTP-glucose-1-phosphate uridylyltransferase
A9258_03985	ENOG41083P1	competence protein ComEA helix-hairpin-helix repeat protein
A9258_03990	ENOG4108RNI	3'(2')5'-bisphosphate nucleotidase
A9258_03995	ENOG4105K9H	YciI-like protein
A9258_04000	ENOG4107835	probably involved in intracellular septation (By similarity)
A9258_04005	ENOG4105DY8	decarboxylase
A9258_04010	ENOG4108UT2	hemolysin iii
A9258_04015	ENOG4105D0C	transport protein
A9258_04025	ENOG4107R88	Chemotaxis protein (CheV)
A9258_04030	ENOG4108UJV	acyl-CoA thioesterase i
A9258_04035	ENOG4108I0Y	(ABC) transporter
A9258_04040	ENOG4105CV6	ABC transporter, permease
A9258_04045	ENOG4105ECP	epimerase
A9258_04050	ENOG4105BZU	Histidine kinase
A9258_04055	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
A9258_04060	ENOG4105IIU	Aminopeptidase
A9258_04065	ENOG4105CZ1	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity)
A9258_04070	ENOG41090ED	Protein with unknown function (DUF469)
A9258_04075	ENOG4105CSV	Glutaminase
A9258_04080	ENOG4107RM6	sulfurtransferase
A9258_04085	ENOG4105RX7	peptidase S8 and S53, subtilisin, kexin, sedolisin
A9258_04090	ENOG4105SUV	lipoprotein YgdR
A9258_04095	ENOG4105BZ1	(ABC) transporter
A9258_04115	ENOG4107G87	m6 family metalloprotease domain protein
A9258_04120	ENOG4105KQT	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome (By similarity)
A9258_04125	ENOG4105BZU	Histidine kinase
A9258_04145	ENOG4105VYA	Uncharacterized conserved protein (DUF2132)
A9258_04150	ENOG4105DJ4	phosphatidylserine decarboxylase
A9258_04155	ENOG4105E06	May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity)
A9258_04160	ENOG4108RBP	3'-to-5' exoribonuclease specific for small oligoribonucleotides (By similarity)
A9258_04200	ENOG4105VEQ	Cold shock protein
A9258_04210	ENOG4105C8Q	Methyl-accepting chemotaxis
A9258_04215	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
A9258_04220	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
A9258_04225	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
A9258_04270	ENOG4109015	Biopolymer transport protein exbD tolR
A9258_04290	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
A9258_04295	ENOG4108I5X	binding-protein-dependent transport systems inner membrane Component
A9258_04300	ENOG4108IYQ	Binding-protein-dependent transport systems inner membrane component
A9258_04315	ENOG4108JQ7	(ABC) transporter
A9258_04320	ENOG4105CIN	aminoacyl-histidine dipeptidase
A9258_04325	ENOG4105DYA	Acts on guanine, xanthine and to a lesser extent hypoxanthine (By similarity)
A9258_04330	ENOG4105V1F	Fermentation respiration switch protein
A9258_04335	ENOG4108UVK	Binds to the sigma-S subunit of RNA polymerase, activating expression of sigma-S-regulated genes. Stimulates RNA polymerase holoenzyme formation and may bind to several other sigma factors, such as sigma-70 and sigma-32 (By similarity)
A9258_04345	ENOG4105C2S	Catalyzes the NADPH dependent reduction of L-gamma- glutamyl 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate (By similarity)
A9258_04375	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
A9258_04385	ENOG4105D7T	ABC transporter
A9258_04390	ENOG4105DG7	nitrate ABC transporter
A9258_04395	ENOG4105D7T	ABC transporter
A9258_04400	ENOG4107QZF	nitrite reductase NADPH large subunit
A9258_04405	ENOG4107QZF	nitrite reductase NADPH large subunit
A9258_04410	ENOG4105DD7	kinase (PfkB family
A9258_04415	ENOG4105D53	Catalyzes the hydrolysis of pseudouridine 5'-phosphate (PsiMP) to ribose 5-phosphate and uracil (By similarity)
A9258_04425	ENOG4105CA0	peroxidase
A9258_04460	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
A9258_04490	ENOG4105C84	Histidine ammonia-lyase
A9258_04515	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
A9258_04525	ENOG4105C2D	reductase
A9258_04530	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
A9258_04540	ENOG4108RIR	Molybdenum cofactor biosynthesis protein
A9258_04550	ENOG4105DWK	Membrane
A9258_04555	ENOG4107XM3	UPF0442 protein
A9258_04565	ENOG4108IJ7	Glycine betaine
A9258_04570	ENOG4108HQS	Glycine betaine
A9258_04575	ENOG4105GIJ	Glycine betaine
A9258_04580	ENOG4105ET3	Reduction of activated sulfate into sulfite (By similarity)
A9258_04585	ENOG4105ET1	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate (By similarity)
A9258_04590	ENOG4107EER	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity)
A9258_04595	ENOG4107TIF	Phenazine biosynthesis protein, PhzF family
A9258_04600	ENOG4105CRK	lysyL-tRNA synthetase
A9258_04605	ENOG4105CG1	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA (By similarity)
A9258_04610	ENOG4105C8Q	Methyl-accepting chemotaxis
A9258_04615	ENOG4105D6U	Sodium Glutamate Symporter
A9258_04620	ENOG4105HDK	L-asparaginase
A9258_04625	ENOG4105VUT	cytoplasmic protein
A9258_04645	ENOG4105D07	Signal peptide peptidase, SppA
A9258_04650	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
A9258_04655	ENOG41069NU	Nitroreductase
A9258_04670	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
A9258_04675	ENOG4105CIS	alcohol dehydrogenase
A9258_04680	ENOG4105HEI	LysR family (Transcriptional regulator
A9258_04685	ENOG4105CI1	PTS System
A9258_04690	ENOG4108IA2	Sodium pantothenate symporter
A9258_04700	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
A9258_04705	ENOG4105KM4	Acetyl-CoA carboxylase, biotin carboxyl carrier protein
A9258_04710	ENOG4108Z38	Catalyzes a trans-dehydration via an enolate intermediate (By similarity)
A9258_04715	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
A9258_04725	ENOG4105BZU	Histidine kinase
A9258_04745	ENOG4109039	Involved in the biogenesis of TorA. Acts on TorA before the insertion of the molybdenum cofactor and, as a result, probably favors a conformation of the apoenzyme that is competent for acquiring the cofactor (By similarity)
A9258_04760	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
A9258_04775	ENOG4108Z11	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes (By similarity)
A9258_04780	ENOG4105D1W	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity)
A9258_04800	ENOG4108UTT	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity)
A9258_04805	ENOG4107YIM	Involved in the transcription termination process (By similarity)
A9258_04810	ENOG4105CG2	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity)
A9258_04815	ENOG4108ZAI	phosphatidylglycerophosphatase a
A9258_04820	ENOG4108JQ6	ABC transporter
A9258_04830	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
A9258_04840	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
A9258_04845	ENOG4105CTB	Polyprenyl synthetase
A9258_04850	ENOG41067QG	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
A9258_04855	ENOG4105E14	MotA TolQ exbB proton channel
A9258_04860	ENOG4107XSU	flagellar motor protein motb
A9258_04865	ENOG4108UKH	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
A9258_04875	ENOG4105HBR	Rna-binding protein
A9258_04880	ENOG4105F7M	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit (By similarity)
A9258_04885	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
A9258_04890	ENOG4105EEI	dihydropteroate synthase
A9258_04895	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
A9258_04900	ENOG4105CP7	Triose-phosphate isomerase
A9258_04920	ENOG4105K7D	Required for maturation of 30S ribosomal subunits (By similarity)
A9258_04925	ENOG4105CHV	Transcription elongation factor NusA
A9258_04930	ENOG4107QHU	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
A9258_04935	ENOG4105KG7	Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity)
A9258_04940	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
A9258_04945	ENOG4105K77	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity)
A9258_04950	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
A9258_04960	ENOG4105BZU	Histidine kinase
A9258_04965	ENOG41090EX	DsrE family
A9258_04980	ENOG4105EQ6	Hydrolyzes dipeptides containing N-terminal aspartate residues. May play a role in allowing the cell to use peptide aspartate to spare carbon otherwise required for the synthesis of the aspartate family of amino acids (By similarity)
A9258_04990	ENOG4108NEV	two component transcriptional regulator, LytTR family
A9258_05000	ENOG4108ZXC	Two component transcriptional regulator, luxr family
A9258_05015	ENOG4105DB1	molybdopterin oxidoreductase
A9258_05045	ENOG4107N1Q	ErfK YbiS YcfS YnhG family protein
A9258_05065	ENOG41071R3	Low-potential electron donor to a number of redox enzymes (By similarity)
A9258_05070	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
A9258_05075	ENOG4105M2E	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell (By similarity)
A9258_05080	ENOG4105T95	Thiol disulfide interChange protein
A9258_05085	ENOG4105C2R	Single-stranded-DNA-specific exonuclease (RecJ)
A9258_05090	ENOG4107SWG	transcriptional regulator MERR family
A9258_05105	ENOG4108IUB	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
A9258_05110	ENOG4105MJ9	esterase
A9258_05120	ENOG4105C0G	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity)
A9258_05125	ENOG4108BDP	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity)
A9258_05130	ENOG4108Z43	UPF0250 protein
A9258_05135	ENOG4105DZ1	carboxypeptidase
A9258_05140	ENOG4105K6T	rare lipoprotein A
A9258_05145	ENOG4105CVE	Lytic murein transglycosylase
A9258_05150	ENOG4105CNI	cell division protein FtsW
A9258_05155	ENOG4105CJN	penicillin-binding protein
A9258_05160	ENOG4108UXA	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA (By similarity)
A9258_05165	ENOG4105KEM	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation (By similarity)
A9258_05170	ENOG4108Z1W	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity)
A9258_05185	ENOG4105C8T	Leucyl-tRNA synthetase
A9258_05190	ENOG4107PAI	alpha helical protein
A9258_05195	ENOG4105CE8	Transfers the fatty acyl group on membrane lipoproteins (By similarity)
A9258_05200	ENOG4108JU5	Magnesium and cobalt efflux protein
A9258_05205	ENOG4105KGE	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA (By similarity)
A9258_05210	ENOG4105C9A	Phoh family
A9258_05215	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
A9258_05220	ENOG4105EAK	ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family
A9258_05225	ENOG4106XMA	In vivo, quickly hydrolyzes the ureidoacrylate peracid to avoid toxicity, but can also hydrolyzes ureidoacrylate that is formed spontaneously from ureidoacrylate peracid. One of the products of hydrolysis, carbamate, hydrolyzes spontaneously, thereby releasing one of the pyrimidine rings nitrogen atoms as ammonia and one of its carbons as CO2 (By similarity)
A9258_05235	ENOG4105BZU	Histidine kinase
A9258_05250	ENOG4105EVE	HAD-superfamily hydrolase subfamily IA variant 3
A9258_05260	ENOG4105BZU	Histidine kinase
A9258_05270	ENOG4105C5I	Dehydrogenase
A9258_05280	ENOG4108R5S	membrane
A9258_05285	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
A9258_05295	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
A9258_05305	ENOG4105DHQ	Histidine kinase
A9258_05310	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
A9258_05345	ENOG4105T0Z	Conserved Protein
A9258_05365	ENOG4108VP9	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane (By similarity)
A9258_05370	ENOG4108WJH	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane (By similarity)
A9258_05375	ENOG4105E33	succinate dehydrogenase
A9258_05385	ENOG4105C8Q	Methyl-accepting chemotaxis
A9258_05390	ENOG4108QXE	glycerophosphoryl diester phosphodiesterase
A9258_05395	ENOG4105EGS	Mechanosensitive ion channel
A9258_05405	ENOG4105DR5	peptidase
A9258_05420	ENOG4105EJC	lysr family transcriptional regulator
A9258_05435	ENOG4105C8Q	Methyl-accepting chemotaxis
A9258_05440	ENOG4105C5Q	Transcriptional regulator
A9258_05445	ENOG4108JQC	penicillin-binding protein 1A
A9258_05470	ENOG4105E4G	Type IV pilus
A9258_05475	ENOG4105KHV	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
A9258_05480	ENOG4105D49	3-dehydroquinate synthase
A9258_05490	ENOG4105DFE	Dna adenine methylase
A9258_05495	ENOG4105DJV	ribulose-phosphate 3-epimerase
A9258_05500	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
A9258_05505	ENOG4105C31	Tryptophanyl-tRNA synthetase
A9258_05520	ENOG4105C8Y	Acetylornithine aminotransferase
A9258_05530	ENOG4105C26	Dehydrogenase
A9258_05540	ENOG4107VXZ	Hydrolase
A9258_05550	ENOG4105D95	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin (By similarity)
A9258_05560	ENOG4105CG3	alpha amylase, catalytic region
A9258_05570	ENOG41060QA	UPF0267 protein
A9258_05580	ENOG4108I5U	Uridine phosphorylase
A9258_05585	ENOG4106Z1T	Nicotinamide Mononucleotide Transporter
A9258_05590	ENOG4107QWE	)-transporter
A9258_05665	ENOG4105C3G	gtp-binding protein
A9258_05670	ENOG4108ZPD	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity)
A9258_05675	ENOG4105CGH	5'-nucleotidase
A9258_05680	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
A9258_05695	ENOG4105C1U	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein (By similarity)
A9258_05700	ENOG4105C7E	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) (By similarity)
A9258_05705	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
A9258_05710	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
A9258_05720	ENOG41063JG	Transcriptional regulator
A9258_05725	ENOG4105CXR	Phospho-2-dehydro-3-deoxyoctonate aldolase
A9258_05730	ENOG4105CK2	sodium dicarboxylate symporter
A9258_05735	ENOG4108VKA	Acts as a radical domain for damaged PFL and possibly other radical proteins (By similarity)
A9258_05740	ENOG4105D5S	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine (By similarity)
A9258_05755	ENOG4105CW3	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
A9258_05760	ENOG4105BZG	amino acid carrier protein
A9258_05765	ENOG4105F8C	transglutaminase domain-containing protein
A9258_05775	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
A9258_05780	ENOG41066YJ	Beta-lactamase
A9258_05785	ENOG4105DUX	Transporter
A9258_05790	ENOG4107Y66	Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity)
A9258_05795	ENOG4108UJU	UPF0301 protein
A9258_05805	ENOG4105D7Z	glutathione synthase
A9258_05810	ENOG4105QF0	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity)
A9258_05820	ENOG4105GPY	SprT protein
A9258_05825	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
A9258_05830	ENOG4105CV1	Transketolase (EC 2.2.1.1)
A9258_05840	ENOG4107XTP	(EAL) domain protein
A9258_05850	ENOG4105KME	endoribonuclease L-psp
A9258_05855	ENOG4105TMR	Functions as a holding molecular chaperone (holdase) which stabilizes unfolding intermediates and rapidly releases them in an active form once stress has abated. Plays an important role in protecting cells from severe heat shock and starvation, as well as in acid resistance of stationary-phase cells. It catalyzes the conversion of methylglyoxal (MG) to D-lactate in a single glutathione (GSH)-independent step (By similarity)
A9258_05865	ENOG4105ED7	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling (By similarity)
A9258_05870	ENOG4105DR5	peptidase
A9258_05875	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
A9258_05880	ENOG4107WCA	isomerase
A9258_05890	ENOG4108V1U	phospholipid-binding protein
A9258_05895	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
A9258_05910	ENOG4105C87	Aminotransferase class I and II
A9258_05920	ENOG4105C5Q	Transcriptional regulator
A9258_05925	ENOG4105UBK	short-chain dehydrogenase reductase
A9258_05930	ENOG4105ERU	peptidase
A9258_05935	ENOG4105EY2	Catalyzes the hydrolysis of N(2)-succinylarginine into N(2)-succinylornithine, ammonia and CO(2) (By similarity)
A9258_05940	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
A9258_05955	ENOG4107RHT	methyl-accepting chemotaxis sensory transducer with Pas Pac sensor
A9258_05960	ENOG4105E2D	ec 3.2.1.52
A9258_05965	ENOG4105RD7	BadF BadG BcrA BcrD
A9258_05975	ENOG4108JQ7	(ABC) transporter
A9258_05985	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
A9258_05995	ENOG4108J59	Extracellular solute-binding protein, family 5
A9258_06000	ENOG4105BZU	Histidine kinase
A9258_06020	ENOG4105XIQ	Protein of unknown function (DUF2517)
A9258_06050	ENOG4107SDU	Methyl-accepting chemotaxis
A9258_06060	ENOG4108ESY	Metal dependent phosphohydrolase
A9258_06065	ENOG4105DR8	Membrane
A9258_06070	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
A9258_06075	ENOG4105C6R	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor (By similarity)
A9258_06080	ENOG4108IUZ	ABC transporter
A9258_06085	ENOG4107A5B	Binding-protein-dependent transport systems, inner membrane component
A9258_06095	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
A9258_06100	ENOG4105BZU	Histidine kinase
A9258_06105	ENOG4105HD0	Transcriptional regulator of molybdate metabolism, LysR family
A9258_06110	ENOG4107H9G	Necessary for formate dehydrogenase activity (By similarity)
A9258_06145	ENOG4108IEG	Formate dehydrogenase Alpha subunit
A9258_06145	ENOG4108IEG	Formate dehydrogenase Alpha subunit
A9258_06150	ENOG4105QAX	Iron-sulfur
A9258_06160	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
A9258_06165	ENOG4107R1I	NAD-dependent malic enzyme
A9258_06180	ENOG4105C2W	permease
A9258_06185	ENOG4105HHQ	6-phosphogluconolactonase (EC 3.1.1.31)
A9258_06225	ENOG4105EGS	Mechanosensitive ion channel
A9258_06230	ENOG4105CA9	Pyruvate kinase
A9258_06245	ENOG4105CKD	glutathione-regulated potassium-efflux system protein
A9258_06255	ENOG4105DH7	May be involved in recombination (By similarity)
A9258_06265	ENOG4107RH8	nuclease SbcCD subunit D
A9258_06270	ENOG4105EYH	Exonuclease
A9258_06275	ENOG4105EYH	Exonuclease
A9258_06285	ENOG4105CPW	cytochrome b561
A9258_06295	ENOG4105BZU	Histidine kinase
A9258_06300	ENOG4105C5Y	PTS System
A9258_06310	ENOG4105KZ7	phosphocarrier protein hpr
A9258_06315	ENOG4105C6T	cysteine synthase
A9258_06320	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
A9258_06335	ENOG4108R96	Methyltransferase, YaeB family
A9258_06355	ENOG4108JJ8	(ABC) transporter
A9258_06360	ENOG4108JJ9	ABC, transporter
A9258_06375	ENOG41065U4	response regulator
A9258_06385	ENOG4108YYX	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. Modulates RNA-binding and helicase activities of the degradosome (By similarity)
A9258_06400	ENOG4105VS7	Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue. This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon. When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation (By similarity)
A9258_06405	ENOG4106FVC	RNA methyltransferase
A9258_06415	ENOG4105D5I	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate (By similarity)
A9258_06420	ENOG4105D98	threonine synthase
A9258_06425	ENOG4108VSZ	Inherit from COG: ketosteroid isomerase-like protein
A9258_06440	ENOG4105C5H	ABC transporter
A9258_06450	ENOG4108QW8	Purine nucleoside phosphorylase deoD-type
A9258_06465	ENOG4105BZU	Histidine kinase
A9258_06470	ENOG4105C8E	extradiol ring-cleavage dioxygenase class IIi protein subunit b
A9258_06475	ENOG4108V1T	peptidylprolyl cis-trans isomerase
A9258_06490	ENOG4105CUB	amino acid
A9258_06500	ENOG4105CUB	amino acid
A9258_06505	ENOG4108JPW	Aminotransferase
A9258_06510	ENOG4105C26	Dehydrogenase
A9258_06515	ENOG4107VRI	Transcriptional regulator
A9258_06520	ENOG4105CJP	fad dependent oxidoreductase
A9258_06550	ENOG4105Q26	Siderophore-interacting protein
A9258_06555	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
A9258_06560	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
A9258_06565	ENOG4105DJY	efflux transporter, rnd family, mfp subunit
A9258_06575	ENOG4105E2M	Manganese-dependent inorganic pyrophosphatase
A9258_06585	ENOG4105C4F	May be involved in recombinational repair of damaged DNA (By similarity)
A9258_06590	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
A9258_06595	ENOG4105K90	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
A9258_06600	ENOG4105CFG	Acts as a chaperone (By similarity)
A9258_06605	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
A9258_06615	ENOG4105D7K	pfkb domain protein
A9258_06630	ENOG4105WBN	Transcriptional regulator (LacI family
A9258_06650	ENOG41080HT	Transcriptional regulator, arsr family
A9258_06675	ENOG4105BZU	Histidine kinase
A9258_06680	ENOG4107RMF	Catalyzes both the ATP-dependent activation of exogenously supplied lipoate to lipoyl-AMP and the transfer of the activated lipoyl onto the lipoyl domains of lipoate-dependent enzymes (By similarity)
A9258_06700	ENOG4108IJF	Heavy metal efflux pump, CzcA
A9258_06705	ENOG4105EP1	Efflux transporter rnd family, mfp subunit
A9258_06725	ENOG4105CGK	Exodeoxyribonuclease III
A9258_06740	ENOG4105E5W	Transporter
A9258_06785	ENOG4105E2S	oxidase) subunit II
A9258_06790	ENOG4105BZ9	Cytochrome C oxidase, subunit I
A9258_06795	ENOG4105CCU	oxidase (Subunit III)
A9258_06800	ENOG41090KH	cytochrome o ubiquinol oxidase (subunit iv)
A9258_06805	ENOG4105F1R	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group (By similarity)
A9258_06810	ENOG4107RDB	Major Facilitator
A9258_06820	ENOG4105E2B	Taurine dioxygenase
A9258_06825	ENOG4105EUS	Binding-protein-dependent transport systems, inner membrane component
A9258_06830	ENOG4108ETV	ABC transporter
A9258_06835	ENOG4106FTQ	Taurine ABC transporter, periplasmic
A9258_06845	ENOG4105D9N	nucleoside
A9258_06865	ENOG4105S2T	inner membrane protein YbcI
A9258_06870	ENOG4105F6H	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate (By similarity)
A9258_06875	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
A9258_06880	ENOG4105DK0	Indole-3-glycerol phosphate synthase
A9258_06885	ENOG4108I0Q	anthranilate phosphoribosyltransferase
A9258_06890	ENOG4108EFP	Anthranilate synthase component II
A9258_06895	ENOG4105CRQ	synthase (Component I)
A9258_06900	ENOG4105DB7	PHP domain protein
A9258_06905	ENOG4107RTD	sua5 ycio yrdc ywlc family protein
A9258_06915	ENOG4105K8I	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves (By similarity)
A9258_06920	ENOG4105FE9	pseudouridine synthase
A9258_06925	ENOG4105C29	acyl-CoA thioesterase
A9258_06940	ENOG4108IG5	Transcriptional regulator
A9258_06945	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
A9258_06950	ENOG4105BZS	acriflavin resistance protein
A9258_06955	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
A9258_06960	ENOG4105C1B	dTDP-glucose 4-6-dehydratase
A9258_06965	ENOG4105DBZ	Dtdp-4-dehydrorhamnose reductase
A9258_06975	ENOG4108URP	Dtdp-4-dehydrorhamnose 3,5-epimerase
A9258_06985	ENOG4105EY8	ABC transporter
A9258_07010	ENOG4105ESV	Glycosyl transferase, family 4
A9258_07020	ENOG4105ESV	Glycosyl transferase, family 4
A9258_07030	ENOG4107QQG	Dehydrogenase
A9258_07060	ENOG4105C5E	polysaccharide biosynthesis protein
A9258_07070	ENOG4105EAG	UDP-N-acetylglucosamine 2-epimerase
A9258_07080	ENOG4105DAY	polysaccharide export protein
A9258_07090	ENOG4105D75	Capsular exopolysaccharide family
A9258_07095	ENOG4105E3R	(LipO)protein
A9258_07105	ENOG4108YXG	UPF0502 protein
A9258_07115	ENOG4105KR1	Trans-acting protein required for termination of DNA replication. Binds to DNA replication terminator sequences (terA to terF) to prevent the passage of replication forks. The termination efficiency will be affected by the affinity of this protein for the terminator sequence (By similarity)
A9258_07130	ENOG4107RUY	(E1 component), alpha subunit
A9258_07135	ENOG4105CPP	Dehydrogenase, E1 component
A9258_07140	ENOG4107QSN	dihydrolipoamide acetyltransferase
A9258_07145	ENOG4105VEQ	Cold shock protein
A9258_07175	ENOG4108594	Permease of the drug metabolite transporter
A9258_07180	ENOG4105N2W	Transcriptional regulator
A9258_07185	ENOG4105C6N	Formate acetyltransferase
A9258_07190	ENOG4105F1A	Pyruvate formate-lyase
A9258_07195	ENOG4107T9Z	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
A9258_07205	ENOG4105CPI	Metal Dependent Phosphohydrolase
A9258_07210	ENOG4105I08	Pseudouridine synthase
A9258_07220	ENOG4107QSI	ABC, transporter
A9258_07225	ENOG4108RE9	Phosphodiesterase
A9258_07240	ENOG4107ESN	Flagella basal body P-ring formation protein flgA
A9258_07245	ENOG4107R88	Chemotaxis protein (CheV)
A9258_07250	ENOG4105BZU	Histidine kinase
A9258_07255	ENOG4105K88	Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body (By similarity)
A9258_07260	ENOG4108ZC9	flagellar basal-body rod protein flgc
A9258_07270	ENOG4105BZE	flagellar hook protein, FlgE
A9258_07275	ENOG4108KPB	Flagellar basal-body rod protein FlgF
A9258_07280	ENOG4105CGA	flagellar basal-body rod protein FlgG
A9258_07285	ENOG4107W7W	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity)
A9258_07290	ENOG4105D92	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity)
A9258_07295	ENOG4108ZW7	flagellar rod assembly protein muramidase flgj
A9258_07300	ENOG4105E1Q	flagellar hook-associated protein
A9258_07305	ENOG4105DTJ	flagellar hook-associated protein
A9258_07310	ENOG4105CJW	magnesium transporter
A9258_07315	ENOG4105C9X	ppx gppa phosphatase
A9258_07320	ENOG4105CUU	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) (By similarity)
A9258_07325	ENOG4105RH4	Glycine cleavage system transcriptional repressor
A9258_07335	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
A9258_07340	ENOG4105BZU	Histidine kinase
A9258_07345	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
A9258_07350	ENOG4107QNR	UPF0135 protein
A9258_07355	ENOG4108V3E	phosphoribosylglycinamide formyltransferase
A9258_07360	ENOG4105CXB	phosphoribosylaminoimidazole synthetase
A9258_07365	ENOG4105CZ5	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate (By similarity)
A9258_07380	ENOG4108I9X	Isocitrate lyase
A9258_07385	ENOG4107QP3	malate synthase g
A9258_07395	ENOG4108Z6B	deaminase
A9258_07400	ENOG4105C8U	phosphate abc transporter
A9258_07405	ENOG4105E2Z	phosphate ABC transporter (Permease
A9258_07410	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
A9258_07420	ENOG4105C37	(CBS) domain
A9258_07430	ENOG4105C3R	Methionine synthase
A9258_07435	ENOG4105D5Q	Arginine ornithine antiporter
A9258_07450	ENOG4105CDA	abc transporter atp-binding protein
A9258_07455	ENOG4105E5Q	amino acid AbC transporter
A9258_07460	ENOG4106TNF	Periplasmic binding protein
A9258_07465	ENOG4105BZU	Histidine kinase
A9258_07470	ENOG4105CXY	transporter
A9258_07475	ENOG4105BZU	Histidine kinase
A9258_07480	ENOG4108KX4	response regulator
A9258_07485	ENOG4105NXH	GreA GreB family elongation factor
A9258_07515	ENOG4105C9W	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity (By similarity)
A9258_07520	ENOG4108ISG	Major Facilitator
A9258_07525	ENOG4105DGU	Histone deacetylase
A9258_07535	ENOG4105DVT	helicase
A9258_07540	ENOG4105QMY	Porin Gram-negative type
A9258_07550	ENOG4105CGF	Aromatic amino acid aminotransferase
A9258_07555	ENOG4105D7A	ATP-binding protein
A9258_07620	ENOG4105CSW	GntR family transcriptional regulator
A9258_07625	ENOG4105UVJ	5-dehydro-4-deoxyglucarate dehydratase
A9258_07635	ENOG4108YXU	transcriptional regulator AsnC family
A9258_07705	ENOG4105CHD	Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) (By similarity)
A9258_07710	ENOG4105W49	UPF0434 protein
A9258_07715	ENOG4105CET	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria (By similarity)
A9258_07720	ENOG4105WH1	Two component transcriptional regulator luxr family
A9258_07725	ENOG4105CII	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity)
A9258_07770	ENOG4105E5H	Transposase
A9258_07780	ENOG4105C26	Dehydrogenase
A9258_07790	ENOG4108HRG	Involved in the cleavage of the C1-C2 bond of 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy- glucuronate (5DG) (By similarity)
A9258_07800	ENOG4105E9V	Periplasmic binding protein LacI transcriptional regulator
A9258_07810	ENOG4105CNN	ABC, transporter
A9258_07820	ENOG4105D7K	pfkb domain protein
A9258_07830	ENOG4105DH8	myo-inositol catabolism
A9258_07835	ENOG4105F2I	Transposase
A9258_07840	ENOG4108ZQS	transposase
A9258_07845	ENOG4108MVM	Transposase
A9258_07910	ENOG4105JJ8	Cytochrome c nitrite reductase, pentaheme subunit
A9258_07915	ENOG4105D3S	4Fe-4S Ferredoxin, iron-sulfur binding domain protein
A9258_07920	ENOG4105DVI	reductase, NrfD
A9258_07925	ENOG4105F10	Catalyzes the hydrolysis of the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1- phosphate (lipid X) and UMP (By similarity)
A9258_07935	ENOG4108R5K	PPIases accelerate the folding of proteins (By similarity)
A9258_07955	ENOG410620I	Diguanylate cyclase
A9258_07990	ENOG4108ZJT	translation initiation factor, Sui1
A9258_08015	ENOG4107QQ4	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans (By similarity)
A9258_08020	ENOG4105CZX	twitching motility protein
A9258_08030	ENOG4105BZU	Histidine kinase
A9258_08035	ENOG4108ESU	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Involved in the translocation of the substrate across the membrane (By similarity)
A9258_08040	ENOG41080WI	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system (By similarity)
A9258_08050	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
A9258_08055	ENOG41080IJ	Diacylglycerol kinase
A9258_08060	ENOG4108JQ1	Dehydrogenase
A9258_08065	ENOG4105E66	phosphoriboisomerase A
A9258_08070	ENOG4105MK2	5-formyltetrahydrofolate cyclo-ligase
A9258_08080	ENOG4105DUK	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity)
A9258_08085	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
A9258_08090	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
A9258_08095	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
A9258_08100	ENOG4107QS8	(LipO)protein
A9258_08105	ENOG4108MIB	
A9258_08125	ENOG4108MK9	spermidine N(1)-acetyltransferase
A9258_08130	ENOG4105C1J	atp-dependent rna helicase
A9258_08155	ENOG4108Z4X	TRANSCRIPTIONal
A9258_08170	ENOG4105EAB	amino acid AbC transporter
A9258_08175	ENOG4105DRP	amino acid AbC transporter
A9258_08180	ENOG4105CDA	abc transporter atp-binding protein
A9258_08185	ENOG4105BZ8	glutamate synthase
A9258_08190	ENOG4105CBC	glutamate synthase
A9258_08195	ENOG4105N5T	Radical SAM Protein
A9258_08205	ENOG4105C42	Type I secretion membrane fusion protein (HlyD
A9258_08250	ENOG4105C85	amino acid
A9258_08260	ENOG4105CF9	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation (By similarity)
A9258_08265	ENOG4108HRN	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate (By similarity)
A9258_08310	ENOG4105D01	(LipO)protein
A9258_08315	ENOG4105EYK	Phosphatidylglycerophosphatase B
A9258_08320	ENOG4105CJ0	Catalyzes the oxidation of erythronate-4-phosphate to 3- hydroxy-2-oxo-4-phosphonooxybutanoate (By similarity)
A9258_08325	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
A9258_08335	ENOG4105DI7	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity)
A9258_08340	ENOG4107QTG	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA (By similarity)
A9258_08345	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
A9258_08350	ENOG4108S3P	Sporulation domain protein
A9258_08355	ENOG4108Z0T	Part of a sulfur-relay system (By similarity)
A9258_08360	ENOG4105EM2	membrane
A9258_08365	ENOG4108MN8	Membrane
A9258_08385	ENOG4105DIJ	Phosphoethanolamine transferase
A9258_08395	ENOG4105FF5	Membrane
A9258_08405	ENOG4107RHT	methyl-accepting chemotaxis sensory transducer with Pas Pac sensor
A9258_08410	ENOG4105BZU	Histidine kinase
A9258_08415	ENOG4108W1A	pseudouridine synthase
A9258_08425	ENOG4105E6K	4-Hydroxyphenylpyruvate dioxygenase
A9258_08430	ENOG4105F1J	Homogentisate 1,2-dioxygenase
A9258_08440	ENOG4108RXX	maleylacetoacetate isomerase
A9258_08445	ENOG4108TGY	Glutathione S-transferase
A9258_08455	ENOG4105CAQ	asparagine synthetase
A9258_08465	ENOG4105CKD	glutathione-regulated potassium-efflux system protein
A9258_08470	ENOG4105D4U	had-superfamily hydrolase, subfamily iia
A9258_08475	ENOG4105EKD	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism (By similarity)
A9258_08480	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
A9258_08485	ENOG4105EE5	Membrane protein terC
A9258_08495	ENOG4105CQB	FAD linked oxidase domain protein
A9258_08505	ENOG4105KA0	thioesterase Superfamily protein
A9258_08515	ENOG4105D3Y	Na H antiporter
A9258_08520	ENOG4105DH5	Responsible for the end-turnover of tRNA specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis (By similarity)
A9258_08530	ENOG4105EIY	sodium-type flagellar protein motY
A9258_08535	ENOG4108UYE	Lactoylglutathione lyase
A9258_08540	ENOG4105CSM	endonuclease III
A9258_08545	ENOG4105DZB	Electron transport complex
A9258_08555	ENOG4105D6A	Electron transport complex
A9258_08565	ENOG4108R3D	Electron transport complex
A9258_08570	ENOG4105DGN	Electron transport complex
A9258_08575	ENOG4108PCN	EamA-like transporter family
A9258_08585	ENOG4107SDU	Methyl-accepting chemotaxis
A9258_08590	ENOG4105RKW	reductase (By
A9258_08595	ENOG4105CSX	c4-dicarboxylate anaerobic carrier
A9258_08600	ENOG4105CHM	Aminotransferase
A9258_08610	ENOG41090BQ	Glutaredoxin
A9258_08615	ENOG4106HRJ	d-alanyl-d-alanine carboxypeptidase
A9258_08620	ENOG4105CFI	type iii restriction protein res subunit
A9258_08625	ENOG4105EFX	secretion protein, HlyD family
A9258_08630	ENOG4105KK7	inner membrane protein YiaW
A9258_08640	ENOG4108NEV	two component transcriptional regulator, LytTR family
A9258_08645	ENOG4108HRK	Histidine kinase
A9258_08650	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
A9258_08655	ENOG4108EKI	Dehydrogenase
A9258_08665	ENOG4105EZI	multiple antibiotic resistance (MarC)-related protein
A9258_08670	ENOG4107QSI	ABC, transporter
A9258_08675	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
A9258_08680	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
A9258_08685	ENOG4105C3U	ABC transporter
A9258_08695	ENOG4108JQ7	(ABC) transporter
A9258_08700	ENOG4105DU1	integral membrane protein, terc
A9258_08705	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
A9258_08715	ENOG4105CK2	sodium dicarboxylate symporter
A9258_08730	ENOG4105CD3	dihydroorotase
A9258_08740	ENOG4108NVR	Methyl-accepting chemotaxis
A9258_08745	ENOG4105K59	histidine triad (HIT) protein
A9258_08780	ENOG4107QN8	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
A9258_08785	ENOG4107RAB	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
A9258_08795	ENOG4105CKW	Inner membrane protein yedI
A9258_08800	ENOG4105DPN	Oligoendopeptidase f
A9258_08805	ENOG4105DPN	Oligoendopeptidase f
A9258_08810	ENOG4105C2W	permease
A9258_08820	ENOG4105CEP	NADH dehydrogenase
A9258_08840	ENOG4105K8R	UPF0145 protein
A9258_08850	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
A9258_08855	ENOG410810Y	Sulfite reductase
A9258_08860	ENOG4107SHJ	sulfite reductase subunit b
A9258_08865	ENOG4105D5B	Sulfite reductase, subunit A
A9258_08870	ENOG4108NRW	Phospholipase, patatin family
A9258_08875	ENOG4105EBE	Peptidase U61, LD-carboxypeptidase A
A9258_08880	ENOG4107T7U	Sulfatase
A9258_08890	ENOG4105CFH	Aspartokinase
A9258_08895	ENOG4107QZM	n-acetylglutamate synthase
A9258_08900	ENOG4107QXP	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
A9258_08925	ENOG4105F2Z	3-oxoadipate enol-lactonase
A9258_08940	ENOG4105CR8	Transcriptional regulator
A9258_08945	ENOG4105DAA	L-lactate
A9258_08955	ENOG4107QR9	Iron-sulfur cluster binding protein
A9258_08960	ENOG4108ZZK	Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source (By similarity)
A9258_08980	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
A9258_08990	ENOG4105C2C	drug resistance transporter, Bcr CflA
A9258_09040	ENOG4105CHH	sulfate transporter
A9258_09085	ENOG4108ZQS	transposase
A9258_09105	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
A9258_09110	ENOG4105C8Q	Methyl-accepting chemotaxis
A9258_09115	ENOG4105BZU	Histidine kinase
A9258_09120	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
A9258_09125	ENOG4105BZU	Histidine kinase
A9258_09130	ENOG4108V3W	Chemotaxis protein, CheW
A9258_09135	ENOG4105C8Q	Methyl-accepting chemotaxis
A9258_09140	ENOG4105CBS	Chea signal transduction histidine kinase
A9258_09150	ENOG4108VYJ	response regulator receiver protein
A9258_09155	ENOG4105E3S	small subunit
A9258_09160	ENOG4105QA4	4Fe-4S Ferredoxin, iron-sulfur binding domain protein
A9258_09165	ENOG4105CJ5	hydrogenase 2 b cytochrome subunit
A9258_09170	ENOG4105DPX	Hydrogenase, large subunit
A9258_09175	ENOG4108USZ	hydrogenase
A9258_09180	ENOG4108WGS	hydrogenase 2-specific chaperone
A9258_09185	ENOG4107RNA	Nickel ABC transporter, periplasmic nickel-binding protein
A9258_09190	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
A9258_09195	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
A9258_09200	ENOG4105C3U	ABC transporter
A9258_09205	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
A9258_09210	ENOG4107RSS	Hydrogenase accessory protein HypB
A9258_09215	ENOG4105WMM	Probably plays a role in a hydrogenase nickel cofactor insertion step (By similarity)
A9258_09220	ENOG4105C45	hydrogenase expression formation protein (HypE)
A9258_09225	ENOG4105CQS	hydrogenase expression formation protein HypD
A9258_09230	ENOG4105WRB	Hydrogenase assembly chaperone hypC hupF
A9258_09240	ENOG4105EM7	Selenocysteine-specific translation elongation factor
A9258_09245	ENOG4105C1Y	Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis (By similarity)
A9258_09250	ENOG4108MG9	hydrogenase 3 maturation protease
A9258_09255	ENOG4105I6X	formate hydrogenlyase maturation
A9258_09260	ENOG4105C47	NADH ubiquinone oxidoreductase 20 kda subunit
A9258_09270	ENOG4105CQV	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
A9258_09275	ENOG4107TDF	Formate hydrogenlyase subunit 4
A9258_09280	ENOG4108JPZ	Monovalent cation H antiporter subunit D
A9258_09285	ENOG4108MFN	small subunit of hydrogenase-3, iron-sulfur protein (part of formate hydrogenlyase (FHL) complex)
A9258_09290	ENOG4105DFH	Transport of potassium into the cell (By similarity)
A9258_09295	ENOG4108RC0	Electron transport protein
A9258_09300	ENOG4107QIW	Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity)
A9258_09305	ENOG4107QIW	Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity)
A9258_09315	ENOG4108JUA	Transcriptional regulator
A9258_09320	ENOG4107H9G	Necessary for formate dehydrogenase activity (By similarity)
A9258_09325	ENOG4105F3K	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity)
A9258_09330	ENOG4105CJX	Molecular chaperone. Has ATPase activity (By similarity)
A9258_09335	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
A9258_09340	ENOG4105CFX	Catalyzes the ferrous insertion into protoporphyrin IX (By similarity)
A9258_09350	ENOG4107RE1	Inosine-guanosine kinase
A9258_09365	ENOG4105BZU	Histidine kinase
A9258_09370	ENOG4107QQ4	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans (By similarity)
A9258_09380	ENOG4105F3T	(LipO)protein
A9258_09390	ENOG4108IQC	2,3-dihydroxybenzoate-AMP ligase
A9258_09395	ENOG4105WQI	isochorismatase
A9258_09400	ENOG4105CEY	Amp-dependent synthetase and ligase
A9258_09405	ENOG4105X17	23-dihydro-2,3-dihydroxybenzoate dehydrogenase
A9258_09415	ENOG4105CEY	Amp-dependent synthetase and ligase
A9258_09420	ENOG4108MES	Periplasmic binding protein
A9258_09425	ENOG4108TSE	Transferase
A9258_09430	ENOG4105E0A	ABC, transporter
A9258_09435	ENOG4105TVJ	transport system, permease
A9258_09440	ENOG4105DQ5	transport system permease protein
A9258_09445	ENOG4105D05	Receptor
A9258_09460	ENOG4105QZU	Inner membrane protein YfeZ
A9258_09465	ENOG4107QUT	magnesium and cobalt transport protein CorA
A9258_09470	ENOG4105DWH	electron transfer flavoprotein-ubiquinone oxidoreductase
A9258_09475	ENOG4105BZJ	Electron transfer flavoprotein
A9258_09480	ENOG4105C10	Electron transfer flavoprotein
A9258_09485	ENOG4107QM1	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine (By similarity)
A9258_09490	ENOG4105CMY	5-enolpyruvylshikimate-3-phosphate synthase
A9258_09495	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
A9258_09500	ENOG4108NVR	Methyl-accepting chemotaxis
A9258_09505	ENOG4105D4P	Coproporphyrinogen iii oxidase
A9258_09510	ENOG4105DVS	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
A9258_09535	ENOG4105DFH	Transport of potassium into the cell (By similarity)
A9258_09540	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
A9258_09545	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
A9258_09550	ENOG4105DFP	Integrase
A9258_09590	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
A9258_09605	ENOG4105FQ6	thiopurine methyltransferase
A9258_09610	ENOG4107VK2	coenzyme PQQ biosynthesis protein PqqF
A9258_09615	ENOG4108BY2	phosphohistidine phosphatase
A9258_09625	ENOG4108IPJ	Membrane
A9258_09630	ENOG4108J59	Extracellular solute-binding protein, family 5
A9258_09635	ENOG4105CZI	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
A9258_09640	ENOG4108JA2	transcriptioN-repair coupling factor
A9258_09650	ENOG4105D60	lipoprotein releasing system transmembrane protein
A9258_09655	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
A9258_09660	ENOG4105D60	lipoprotein releasing system transmembrane protein
A9258_09675	ENOG4105DEA	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation
A9258_09680	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
A9258_09685	ENOG4105CHN	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
A9258_09690	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
A9258_09700	ENOG4105EIN	peptidylprolyl cis-trans isomerase
A9258_09705	ENOG4105C5H	ABC transporter
A9258_09710	ENOG4107QN1	sodium solute
A9258_09715	ENOG41062QD	Membrane
A9258_09730	ENOG41060WC	Enoyl-CoA hydratase
A9258_09765	ENOG4105BZG	amino acid carrier protein
A9258_09780	ENOG4106HK8	GPR1 FUN34 yaaH family protein
A9258_09815	ENOG4107QX3	carboxylase
A9258_09820	ENOG4105C1G	acyl-Coa dehydrogenase
A9258_09825	ENOG4105C26	Dehydrogenase
A9258_09830	ENOG4105C1G	acyl-Coa dehydrogenase
A9258_09835	ENOG4105E39	Enoyl-CoA hydratase
A9258_09840	ENOG4105E39	Enoyl-CoA hydratase
A9258_09845	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
A9258_09850	ENOG4105CHR	reductase
A9258_09855	ENOG4105D5Q	Arginine ornithine antiporter
A9258_09860	ENOG4105HF0	Membrane
A9258_09885	ENOG4105BZU	Histidine kinase
A9258_09890	ENOG4105BZU	Histidine kinase
A9258_09895	ENOG4105W5Q	DNA repair protein (RadC
A9258_09960	ENOG4105EQ2	LysR family Transcriptional regulator
A9258_09965	ENOG4105ENX	hydrolase
A9258_09970	ENOG4105DRY	peptidase s9 prolyl oligopeptidase active site domain protein
A9258_09980	ENOG4105HEI	LysR family (Transcriptional regulator
A9258_09985	ENOG4105CPC	Aldo Keto reductase
A9258_10000	ENOG4105BZU	Histidine kinase
A9258_10005	ENOG4108KB2	LysR family Transcriptional regulator
A9258_10010	ENOG4105CS2	ec 3.2.1.21
A9258_10015	ENOG4105BZU	Histidine kinase
A9258_10025	ENOG4105DHT	Metal Dependent Phosphohydrolase
A9258_10030	ENOG4105CHR	reductase
A9258_10035	ENOG4105CBN	LysR family transcriptional regulator
A9258_10040	ENOG4105EFU	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin (By similarity)
A9258_10050	ENOG4105DUM	transcriptional regulator, lysR family
A9258_10060	ENOG4105NWR	lipid A biosynthesis (Kdo)2-(Lauroyl)-lipid IVA acyltransferase
A9258_10065	ENOG4105NWR	lipid A biosynthesis (Kdo)2-(Lauroyl)-lipid IVA acyltransferase
A9258_10090	ENOG4105CQ2	DNA polymerase
A9258_10120	ENOG4107QI1	Mate efflux family protein
A9258_10125	ENOG4105W1I	UPF0253 protein
A9258_10130	ENOG4108R6K	riboflavin synthase, subunit alpha
A9258_10140	ENOG4107UW8	HAD-superfamily hydrolase subfamily IA variant 3
A9258_10145	ENOG4108HH9	Catalyzes two reactions the first one is the production of beta-formyl glycinamide ribonucleotide (GAR) from formate, ATP and beta GAR
A9258_10150	ENOG4108SXK	Transporter Drug Metabolite Exporter family
A9258_10155	ENOG4108V3G	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity)
A9258_10190	ENOG4105XW2	UPF0263 protein
A9258_10195	ENOG4108VKV	Monofunctional biosynthetic peptidoglycan transglycosylase
A9258_10205	ENOG4105VJP	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell (By similarity)
A9258_10210	ENOG4107QMS	site-determining protein
A9258_10215	ENOG4105K7U	Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization (By similarity)
A9258_10220	ENOG4105VNG	YcgL domain-containing protein
A9258_10225	ENOG4105CVE	Lytic murein transglycosylase
A9258_10230	ENOG4105EJQ	L-serine dehydratase
A9258_10235	ENOG4105EJQ	L-serine dehydratase
A9258_10240	ENOG4105NBK	UPF0345 protein
A9258_10245	ENOG4105CK2	sodium dicarboxylate symporter
A9258_10255	ENOG4105CHU	acetyl-coa acetyltransferase
A9258_10260	ENOG4105D58	Diguanylate phosphodiesterase
A9258_10265	ENOG4105CKF	membrane protein involved in aromatic hydrocarbon degradation
A9258_10270	ENOG4105CKF	membrane protein involved in aromatic hydrocarbon degradation
A9258_10280	ENOG4105EMN	RNA polymerase sigma factor
A9258_10310	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
A9258_10315	ENOG4105CHU	acetyl-coa acetyltransferase
A9258_10320	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
A9258_10330	ENOG4108VWS	Yaeq family
A9258_10350	ENOG4108TVE	i protein
A9258_10355	ENOG4108JUB	Transcriptional regulator
A9258_10360	ENOG4105IW6	Carbamoyltransferase
A9258_10365	ENOG4107RCH	Diaminopropionate ammonia-lyase
A9258_10370	ENOG4107S4Y	M20 DapE family protein YgeY
A9258_10380	ENOG4105C5B	carbamate kinase
A9258_10385	ENOG4108Q5Y	Membrane
A9258_10390	ENOG4107P0T	Selenium-dependent molybdenum hydroxylase system protein, YqeB family
A9258_10395	ENOG4105MJ6	selenium-dependent hydroxylase accessory protein YqeC
A9258_10405	ENOG4105BZ8	glutamate synthase
A9258_10410	ENOG4107UUR	Chlorohydrolase aminohydrolase
A9258_10415	ENOG410873Y	FAD binding domain in molybdopterin dehydrogenase
A9258_10420	ENOG4105C7W	Xanthine dehydrogenase
A9258_10425	ENOG4105C2W	permease
A9258_10430	ENOG4107QUY	Guanine deaminase
A9258_10435	ENOG4105C7N	Xanthine uracil vitamin C permease
A9258_10440	ENOG4105C7W	Xanthine dehydrogenase
A9258_10445	ENOG4108HR6	Dehydrogenase
A9258_10450	ENOG4108UTP	(2Fe-2S)-binding domain protein
A9258_10460	ENOG4107MBR	17 kDa surface antigen
A9258_10470	ENOG4105CSX	c4-dicarboxylate anaerobic carrier
A9258_10475	ENOG4105CEY	Amp-dependent synthetase and ligase
A9258_10480	ENOG4105K8F	Phosphoribosyl-amp cyclohydrolase
A9258_10485	ENOG4105C0S	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity)
A9258_10490	ENOG4105BZU	Histidine kinase
A9258_10500	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
A9258_10505	ENOG4105CJV	Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase
A9258_10510	ENOG4108UJE	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity)
A9258_10520	ENOG4105CIH	Imidazole acetol-phosphate transaminase
A9258_10525	ENOG4105CEK	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity)
A9258_10530	ENOG4105E21	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity)
A9258_10540	ENOG4105DVT	helicase
A9258_10545	ENOG41072GX	Peptidase M22 Glycoprotease
A9258_10555	ENOG410626R	Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity)
A9258_10560	ENOG4105CEY	Amp-dependent synthetase and ligase
A9258_10565	ENOG4105ZIE	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides (By similarity)
A9258_10570	ENOG4106PMH	Extracellular solute-binding protein family 3
A9258_10680	ENOG4107TII	Recombinase
A9258_10690	ENOG4105FBT	Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs (By similarity)
A9258_10695	ENOG4105WD1	Membrane
A9258_10700	ENOG4109003	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity)
A9258_10705	ENOG4107QMP	dna polymerase iii subunits gamma and tau
A9258_10710	ENOG4105KDX	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection (By similarity)
A9258_10730	ENOG4105CQ7	ATP-dependent helicase
A9258_10745	ENOG4105BZU	Histidine kinase
A9258_10750	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
A9258_10755	ENOG4105C5X	domain protein
A9258_10760	ENOG4105CR7	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA (By similarity)
A9258_10765	ENOG4105D4F	Synthesizes selenophosphate from selenide and ATP (By similarity)
A9258_10775	ENOG4105FAT	Acyl-transferase
A9258_10785	ENOG4105DR4	Methyltransferase
A9258_10790	ENOG4108N3W	hemolysin secretion protein
A9258_10795	ENOG4105VSY	K01512 acylphosphatase EC 3.6.1.7
A9258_10800	ENOG4108K3A	Glutathione S-transferase
A9258_10805	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
A9258_10810	ENOG4105D1F	ATP-binding protein
A9258_10815	ENOG4105DBI	uridine monophosphokinase
A9258_10820	ENOG4105DHP	deoxycytidine triphosphate deaminase
A9258_10825	ENOG4105CJ3	phosphate transporter
A9258_10830	ENOG4105C03	ribonuclease
A9258_10835	ENOG4105EI2	Pseudouridine synthase
A9258_10845	ENOG4108UHJ	MAF-like protein
A9258_10850	ENOG4105CNH	Multidrug resistance protein MdtL
A9258_10865	ENOG4105FCQ	metal-binding, possibly nucleic acid-binding protein
A9258_10870	ENOG4105VGS	50s ribosomal protein l32
A9258_10875	ENOG4105C6B	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA (By similarity)
A9258_10880	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
A9258_10885	ENOG4105CJF	Malonyl coA-acyl carrier protein transacylase
A9258_10890	ENOG4105CHR	reductase
A9258_10895	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
A9258_10900	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
A9258_10905	ENOG4105YAZ	4-amino-4-deoxychorismate lyase
A9258_10910	ENOG4105HHA	aminodeoxychorismate lyase
A9258_10915	ENOG4108ZMD	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity)
A9258_10920	ENOG4107QRG	dna polymerase iii
A9258_10925	ENOG4105F8V	Hydrolase, tatD family
A9258_10940	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
A9258_10945	ENOG4105DY2	Paraquat-inducible protein b
A9258_10950	ENOG4105F1S	paraquat-inducible protein a
A9258_10960	ENOG4105CR4	methylisocitrate lyase
A9258_10965	ENOG4105BZN	citrate synthase
A9258_10970	ENOG4105DXD	2-methylcitrate dehydratase
A9258_11010	ENOG4105PDP	Short chain dehydrogenase
A9258_11020	ENOG4105X2V	dna damage-inducible protein
A9258_11030	ENOG4105DAN	ATP-dependent protease
A9258_11035	ENOG4108RKI	Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl- ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)- decenoyl-ACP. Can catalyze the dehydratase reaction for beta- hydroxyacyl-ACPs with saturated chain lengths up to 16 0, being most active on intermediate chain length (By similarity)
A9258_11045	ENOG4105C5H	ABC transporter
A9258_11055	ENOG4105C4H	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA (By similarity)
A9258_11060	ENOG4108T7E	Contributes to the efficiency of the cell division process by stabilizing the polymeric form of the cell division protein FtsZ. Acts by promoting interactions between FtsZ protofilaments and suppressing the GTPase activity of FtsZ (By similarity)
A9258_11065	ENOG4107QYT	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor (By similarity)
A9258_11070	ENOG4105C7I	Dehydrogenase
A9258_11080	ENOG4105CD8	aminopeptidase N
A9258_11085	ENOG4105CN1	protease
A9258_11090	ENOG41073DY	may be a structural element that influences the osmotic activation of ProP at a post-translational level (By similarity)
A9258_11095	ENOG4108ZGC	gaf domain protein
A9258_11105	ENOG4105EUH	cytochrome C oxidase, cbb3-type, subunit i
A9258_11120	ENOG4105D6P	C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex (By similarity)
A9258_11145	ENOG4105DS0	Transcriptional regulator, Crp Fnr family
A9258_11150	ENOG4105Q9Y	Universal stress protein
A9258_11155	ENOG4105CB3	Required for the thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32) (By similarity)
A9258_11170	ENOG4108RXX	maleylacetoacetate isomerase
A9258_11175	ENOG4105MRB	Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose (By similarity)
A9258_11180	ENOG4105C2J	ABC transporter
A9258_11185	ENOG4105CNN	ABC, transporter
A9258_11190	ENOG4105E9V	Periplasmic binding protein LacI transcriptional regulator
A9258_11195	ENOG4108RVA	ribokinase
A9258_11200	ENOG4105ETE	Transcriptional regulator (LacI family
A9258_11215	ENOG4105NDF	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity)
A9258_11230	ENOG4105BZU	Histidine kinase
A9258_11235	ENOG4108ZUF	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
A9258_11240	ENOG4105C6A	phenylalanyl-tRNA synthetase (beta subunit)
A9258_11245	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
A9258_11250	ENOG4108YZX	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity)
A9258_11255	ENOG41083UC	50s ribosomal protein L35
A9258_11260	ENOG4108UUX	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity)
A9258_11265	ENOG4105C22	threonyL-tRNA synthetase
A9258_11280	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
A9258_11285	ENOG4108HWB	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
A9258_11290	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
A9258_11295	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
A9258_11300	ENOG4105E05	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
A9258_11305	ENOG4105XPH	Ferredoxin
A9258_11310	ENOG4105CA3	membrane-bound lytic murein transglycosylase
A9258_11315	ENOG4105XZD	Fe-S protein
A9258_11320	ENOG4107SZR	mannose-6-phosphate isomerase
A9258_11325	ENOG4105F3R	pts system mannose fructose sorbose family iid
A9258_11330	ENOG4105ETZ	PTS System
A9258_11335	ENOG4108EQA	pts system
A9258_11350	ENOG4107P2S	Transcriptional regulator
A9258_11355	ENOG4108Y83	glucose-6-phosphate isomerase
A9258_11360	ENOG4105DM4	PTS System
A9258_11365	ENOG4105DE4	1-phosphofructokinase
A9258_11370	ENOG4105DTZ	bifunctional PTS system fructose-specific transporter subunit IIA HPr protein
A9258_11375	ENOG4107B7Y	DNA-binding transcriptional regulator FruR
A9258_11380	ENOG4105E0U	tyrosine-specific transport protein
A9258_11395	ENOG4105C1J	atp-dependent rna helicase
A9258_11405	ENOG4105D10	5-enolpyruvylshikimate-3-phosphate phospholyase
A9258_11410	ENOG4105C76	Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue (By similarity)
A9258_11415	ENOG4108DG9	Smr protein MutS2
A9258_11425	ENOG4105BZU	Histidine kinase
A9258_11430	ENOG4105DKJ	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
A9258_11455	ENOG4108Z8G	Alkylphosphonate utilization operon protein PhnA
A9258_11485	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
A9258_11505	ENOG4105DUC	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division (By similarity)
A9258_11510	ENOG4105DAH	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF (By similarity)
A9258_11520	ENOG4106371	Methyltransferase
A9258_11525	ENOG4107S90	membrAne
A9258_11535	ENOG4105CTQ	phosphohexokinase
A9258_11540	ENOG4105CH2	amidohydrolase
A9258_11545	ENOG4105PAD	Hydrolase
A9258_11550	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
A9258_11580	ENOG4105CPB	ATP-dependent endonuclease of the OLD family
A9258_11595	ENOG4105VP0	transcriptional regulator, lysR family
A9258_11600	ENOG4105EJ9	Membrane
A9258_11605	ENOG4106IUH	DTW domain containing protein
A9258_11615	ENOG4105CPF	Cell wall formation (By similarity)
A9258_11625	ENOG4108V06	Glutathione peroxidase
A9258_11630	ENOG4105C1J	atp-dependent rna helicase
A9258_11635	ENOG4105K5X	acetyltransferase
A9258_11645	ENOG4105KK4	UPF0060 membrane protein
A9258_11675	ENOG41061CK	Antibiotic biosynthesis monooxygenase
A9258_11680	ENOG4107XGF	functions in a salvage pathway. Uses pyridoxamine (By similarity)
A9258_11700	ENOG4105D1N	poly(r)-hydroxyalkanoic acid synthase, class
A9258_11710	ENOG4105WQ3	Rna-binding protein
A9258_11720	ENOG4105BZ1	(ABC) transporter
A9258_11725	ENOG4105BZ1	(ABC) transporter
A9258_11730	ENOG4105BZU	Histidine kinase
A9258_11735	ENOG4105K63	Thioredoxin
A9258_11740	ENOG4105C8P	)-transporter
A9258_11745	ENOG4107QQN	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties (By similarity)
A9258_11780	ENOG4105C44	Serine transporter
A9258_11785	ENOG4107QV7	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system) (By similarity)
A9258_11790	ENOG4105C9U	ATP-dependent DNA helicase RecQ
A9258_11795	ENOG4105CYN	Serine protein kinase
A9258_11805	ENOG4105ED1	spovr family
A9258_11810	ENOG4105C05	Multifunctional regulator of fatty acid metabolism (By similarity)
A9258_11815	ENOG4105DKR	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity)
A9258_11820	ENOG410635M	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein (By similarity)
A9258_11825	ENOG4105DQR	SNARE associated Golgi
A9258_11835	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
A9258_11845	ENOG4105D0C	transport protein
A9258_11850	ENOG4105CHQ	Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella (By similarity)
A9258_11870	ENOG4108MRH	transcriptional regulatory protein
A9258_11875	ENOG4105CEQ	signal transduction histidine kinase regulating citrate malate metabolism
A9258_11880	ENOG4105E2R	ROK family
A9258_11885	ENOG4105C8Q	Methyl-accepting chemotaxis
A9258_11890	ENOG4105K5B	UPF0225 protein
A9258_11895	ENOG4107R5Y	anaerobic glycerol-3-phosphate dehydrogenase, subunit A
A9258_11900	ENOG4108KJ0	anaerobic glycerol-3-phosphate dehydrogenase, subunit B
A9258_11905	ENOG4105CHG	glycolate oxidase (iron-sulfur subunit)
A9258_11925	ENOG4105JJ8	Cytochrome c nitrite reductase, pentaheme subunit
A9258_11930	ENOG4105D3S	4Fe-4S Ferredoxin, iron-sulfur binding domain protein
A9258_11935	ENOG4105DVI	reductase, NrfD
A9258_11940	ENOG4105DA4	cytochrome c-type biogenesis protein
A9258_11945	ENOG4107QX9	Thiol disulfide interChange protein
A9258_11950	ENOG4108DMF	Cytochrome C biogenesis protein
A9258_11955	ENOG4108Z4K	mutator MutT protein
A9258_11960	ENOG41061WM	D-Alanyl-D-Alanine
A9258_11965	ENOG4105C0F	tryptophanase EC 4.1.99.1
A9258_11970	ENOG4105EXX	Deoxyribodipyrimidine photolyase-related protein
A9258_11975	ENOG4105MWK	D-amino acid dehydrogenase, small subunit
A9258_11990	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
A9258_12000	ENOG4105DSS	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation (By similarity)
A9258_12005	ENOG4105DZ2	Transcriptional regulator
A9258_12015	ENOG4105E0K	tonB-dependent siderophore receptor
A9258_12020	ENOG4108XW0	May be a transcriptional activator of genes involved in the multiple antibiotic resistance (Mar) phenotype. It can also activate genes such as sodA, zwf and micF
A9258_12030	ENOG4105CR8	Transcriptional regulator
A9258_12035	ENOG4108RYK	Nad-dependent epimerase dehydratase
A9258_12045	ENOG4105C28	cystathionine
A9258_12055	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
A9258_12060	ENOG4105KPY	Small multidrug resistance protein
A9258_12065	ENOG4105DDY	UPF0142 protein ycaO
A9258_12070	ENOG4105TMB	Formate nitrite transporter
A9258_12075	ENOG4105C6N	Formate acetyltransferase
A9258_12080	ENOG4108KAZ	Involved in phosphonate degradation (By similarity)
A9258_12085	ENOG4108JPW	Aminotransferase
A9258_12090	ENOG4107STF	Involved in phosphonate degradation (By similarity)
A9258_12100	ENOG4105C4Y	ABC transporter
A9258_12110	ENOG4107RCV	ABC transporter, permease
A9258_12115	ENOG4105CJP	fad dependent oxidoreductase
A9258_12130	ENOG4105CH8	Succinyl-CoA ligase ADP-forming subunit alpha
A9258_12135	ENOG4105CMV	Succinyl-CoA synthetase subunit beta
A9258_12140	ENOG4105C7S	Dehydrogenase
A9258_12145	ENOG4105C7P	2-oxoglutarate dehydrogenase, E1
A9258_12150	ENOG4105E33	succinate dehydrogenase
A9258_12155	ENOG4105C00	Succinate dehydrogenase (Flavoprotein subunit)
A9258_12160	ENOG4105N1I	succinate dehydrogenase, hydrophobic membrane anchor protein
A9258_12165	ENOG4108UTY	succinate dehydrogenase, cytochrome b556 subunit
A9258_12170	ENOG4105BZN	citrate synthase
A9258_12185	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
A9258_12190	ENOG4105CWG	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34 (By similarity)
A9258_12200	ENOG4105CEE	C4-dicarboxylate transporter
A9258_12215	ENOG4108VKG	metal-dependent hydrolase
A9258_12230	ENOG4105NRA	50s ribosomal protein l31 type b
A9258_12240	ENOG4105EUB	pirin domain protein
A9258_12245	ENOG4105HEI	LysR family (Transcriptional regulator
A9258_12255	ENOG4105CNN	ABC, transporter
A9258_12265	ENOG4105DMK	Periplasmic binding protein LacI transcriptional regulator
A9258_12270	ENOG4105EF1	ribulokinase
A9258_12280	ENOG4105CAC	Catalyzes the conversion of L-arabinose to L-ribulose (By similarity)
A9258_12285	ENOG4105CJB	Exodeoxyribonuclease I
A9258_12295	ENOG4107R49	K07407 alpha-galactosidase EC 3.2.1.22
A9258_12305	ENOG41067MG	lrgb family
A9258_12310	ENOG4107T42	This enzyme scavenge exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis (By similarity)
A9258_12315	ENOG4108IQE	Amp-dependent synthetase and ligase
A9258_12320	ENOG4105MH2	YfcL protein
A9258_12330	ENOG4105EE5	Membrane protein terC
A9258_12335	ENOG41090EK	ompa motb domain protein
A9258_12340	ENOG4108KHX	Diguanylate cyclase
A9258_12345	ENOG4108WS1	
A9258_12355	ENOG41090A4	Pterin carbinolamine dehydratase
A9258_12360	ENOG41090A4	Pterin carbinolamine dehydratase
A9258_12365	ENOG4105MIR	Phenylalanine 4-monooxygenase
A9258_12370	ENOG4106K28	UPF0283 membrane protein
A9258_12375	ENOG4105CM6	amino acid regulated cytosolic protein
A9258_12385	ENOG4105YYT	phage shock protein B
A9258_12390	ENOG41087YS	Phage shock protein A
A9258_12395	ENOG4105E51	psp operon transcriptional activator
A9258_12400	ENOG4108J59	Extracellular solute-binding protein, family 5
A9258_12405	ENOG4108I5W	peptide transport system, permease protein
A9258_12410	ENOG4108EU3	peptide transport system, permease
A9258_12415	ENOG4108JQ3	Peptide ABC transporter ATP-binding protein
A9258_12420	ENOG4108JQ2	peptide transport system atp-binding protein
A9258_12425	ENOG4105FR9	TRNA-(Ms 2 io 6 A)-hydroxylase
A9258_12430	ENOG4105CBA	glutamine phosphoribosylpyrophosphate amidotransferase
A9258_12435	ENOG4105E96	Colicin v production protein
A9258_12440	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
A9258_12450	ENOG4105D1H	recombination factor protein RarA
A9258_12455	ENOG4107Y7W	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) (By similarity)
A9258_12460	ENOG4105CNU	cell division protein FtsK
A9258_12465	ENOG4105EW9	transcriptional regulator AsnC family
A9258_12470	ENOG4105C3M	thioredoxin reductase
A9258_12475	ENOG4105BZU	Histidine kinase
A9258_12480	ENOG4107MBR	17 kDa surface antigen
A9258_12485	ENOG4108R4Z	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine (By similarity)
A9258_12490	ENOG4105DWA	May conjugate Arg from its aminoacyl-tRNA to the N- termini of proteins containing an N-terminal aspartate or glutamate
A9258_12495	ENOG4105K9U	however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity)
A9258_12500	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
A9258_12505	ENOG4105KAE	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation (By similarity)
A9258_12510	ENOG4105VEQ	Cold shock protein
A9258_12515	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
A9258_12545	ENOG4105CS6	Rhs element vgr protein
A9258_12550	ENOG4108WC9	type VI secretion system effector, hcp1 family
A9258_12565	ENOG4108RMJ	sensory transduction regulator
A9258_12575	ENOG4107104	thymidine kinase
A9258_12580	ENOG4107S6Z	Na H antiporter
A9258_12590	ENOG4108WBT	adenosyltransferase
A9258_12595	ENOG4105VRT	cytoplasmic protein
A9258_12600	ENOG4105EIZ	Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity)
A9258_12605	ENOG4105FD2	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) (By similarity)
A9258_12620	ENOG4106EG9	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) (By similarity)
A9258_12625	ENOG4105CFV	Tetratricopeptide repeat protein
A9258_12635	ENOG41080YA	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
A9258_12640	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
A9258_12645	ENOG4105CAT	Cytidine monophosphate kinase
A9258_12650	ENOG4108JEN	Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate (By similarity)
A9258_12655	ENOG4107R11	Transcriptional regulator
A9258_12660	ENOG4105CMU	LysR family (Transcriptional regulator
A9258_12665	ENOG4105D2S	major facilitator superfamily
A9258_12680	ENOG4108DBC	nitroreductase
A9258_12685	ENOG4105BZU	Histidine kinase
A9258_12695	ENOG4105CBN	LysR family transcriptional regulator
A9258_12700	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
A9258_12725	ENOG4107RGM	aldo keto reductase
A9258_12730	ENOG4105VFU	Rna-binding protein
A9258_12740	ENOG4105HPZ	Involved in the removal of murein from the sacculus. May also facilitate integration of nascent murein strands into the sacculus by cleaving the peptide bonds between neighboring strands in mature murein (By similarity)
A9258_12750	ENOG4105HA9	of methanol dehydrogenase type
A9258_12765	ENOG4105E14	MotA TolQ exbB proton channel
A9258_12770	ENOG4105ER2	Ompa motb domain protein
A9258_12775	ENOG4105KWU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
A9258_12780	ENOG4105ES3	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
A9258_12785	ENOG4105CQV	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
A9258_12790	ENOG4105GKE	subunit e
A9258_12795	ENOG4107QIZ	NADH dehydrogenase
A9258_12800	ENOG4108IEH	NADH dehydrogenase subunit g
A9258_12805	ENOG4105CMZ	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone (By similarity)
A9258_12810	ENOG4105P3U	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
A9258_12815	ENOG4107UFS	subunit j
A9258_12820	ENOG41080EA	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
A9258_12825	ENOG4105D65	subunit l
A9258_12830	ENOG4105C8S	subunit m
A9258_12835	ENOG4105CNR	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
A9258_12845	ENOG4107QIK	phosphoribosylformylglycinamidine synthase
A9258_12850	ENOG4105CHQ	Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella (By similarity)
A9258_12855	ENOG4105VPD	cellular component movement
A9258_12860	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
A9258_12865	ENOG4105CNE	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
A9258_12870	ENOG4105N21	Membrane
A9258_12875	ENOG4105CUT	histidyl-tRNA synthetase
A9258_12880	ENOG4105C4E	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (By similarity)
A9258_12885	ENOG4105HSZ	Cytoskeletal protein that is involved in cell-shape control through regulation of the length of the long axis (By similarity)
A9258_12895	ENOG4105C55	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
A9258_12900	ENOG4108UGX	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity)
A9258_12905	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
A9258_12915	ENOG4108ZIT	Ferredoxin, 2FE-2S
A9258_12920	ENOG4105C9I	Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB
A9258_12925	ENOG4108SWN	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA (By similarity)
A9258_12930	ENOG4108Z4V	iron-sulfur cluster assembly
A9258_12935	ENOG4107XTC	May be involved in the formation or repair of Fe-S clusters present in iron-sulfur proteins
A9258_12940	ENOG4105C3J	Cysteine desulfurase
A9258_12960	ENOG4105XPQ	lipid carrier protein
A9258_12965	ENOG4105CFP	Peptidase U32
A9258_12970	ENOG4106RZ4	Peptidase U32
A9258_12985	ENOG4107RAB	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
A9258_12990	ENOG4107QN8	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
A9258_12995	ENOG4105VIE	preprotein translocase, subunit YajC
A9258_13000	ENOG4105C6U	Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity)
A9258_13005	ENOG4105E2N	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) (By similarity)
A9258_13010	ENOG4105W87	Cbs domain
A9258_13015	ENOG4105D3R	alkyl hydroperoxide reductase
A9258_13025	ENOG4108ISG	Major Facilitator
A9258_13040	ENOG4105K89	arsenate reductase
A9258_13045	ENOG4105D6J	arsenicaL-resistance protein
A9258_13050	ENOG41085FC	arsR family transcriptional regulator
A9258_13055	ENOG4105CBI	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
A9258_13060	ENOG4105KE9	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity)
A9258_13065	ENOG4105D43	The glycine cleavage system catalyzes the degradation of glycine (By similarity)
A9258_13070	ENOG4105EAK	ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family
A9258_13075	ENOG4105D0A	hydroxylase
A9258_13085	ENOG4107YUN	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division (By similarity)
A9258_13095	ENOG4105E5M	Multidrug resistance protein D
A9258_13100	ENOG4105CYM	Glutathione S-transferase
A9258_13115	ENOG4108NVR	Methyl-accepting chemotaxis
A9258_13130	ENOG4105DUF	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively (By similarity)
A9258_13145	ENOG4105C5E	polysaccharide biosynthesis protein
A9258_13165	ENOG4105CDM	Glutamate-1-semialdehyde aminotransferase
A9258_13200	ENOG4105MQ3	flagellar protein FliS
A9258_13215	ENOG4105I03	Flagellin
A9258_13230	ENOG4105I03	Flagellin
A9258_13235	ENOG4105I03	Flagellin
A9258_13240	ENOG4105EN6	Membrane
A9258_13250	ENOG4105D8I	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS (By similarity)
A9258_13260	ENOG4108JQB	penicillin-binding protein 1C
A9258_13265	ENOG4105DN3	alpha-2-macroglobulin domain protein
A9258_13270	ENOG4105CH2	amidohydrolase
A9258_13275	ENOG4105IPI	Membrane
A9258_13280	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
A9258_13285	ENOG4105J12	Multidrug resistance protein mdtN
A9258_13300	ENOG4107QMW	pyridine nucleotide-disulfide oxidoreductase
A9258_13305	ENOG4105BZU	Histidine kinase
A9258_13310	ENOG4105F1A	Pyruvate formate-lyase
A9258_13325	ENOG4105DSP	amino acid AbC transporter
A9258_13330	ENOG4106PMH	Extracellular solute-binding protein family 3
A9258_13335	ENOG4108JEH	abc transporter atp-binding protein
A9258_13340	ENOG4105DWU	Membrane
A9258_13345	ENOG4105DYB	Isoaspartyl dipeptidase
A9258_13350	ENOG4108ZYK	Acyl carrier protein phosphodiesterase
A9258_13365	ENOG4105K89	arsenate reductase
A9258_13375	ENOG4105ERG	peptidase m48, ste24p
A9258_13380	ENOG41082K8	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Interacts with IscS and stimulates its activity. Then, accepts a sulfur from IscS and transfers it in turn to TusD (By similarity)
A9258_13400	ENOG4105CSR	polyphosphate kinase 2
A9258_13405	ENOG4108IJ9	(ABC) transporter
A9258_13410	ENOG4105EG2	ABC transporter, permease
A9258_13415	ENOG4105D56	permease protein
A9258_13420	ENOG4107FKK	extracellular solute-binding protein family 1
A9258_13425	ENOG4106V8H	Nucleoid-associated protein
A9258_13430	ENOG4105PAN	UPF0352 protein
A9258_13435	ENOG4105E68	Sulfatase
A9258_13440	ENOG4105D05	Receptor
A9258_13445	ENOG4105CUG	Oligopeptidase b
A9258_13465	ENOG4108QSZ	General inhibitor of pancreatic serine proteases inhibits chymotrypsin, trypsin, elastases, factor X, kallikrein as well as a variety of other proteases (By similarity)
A9258_13470	ENOG4108WFC	UPF0438 protein yifE
A9258_13475	ENOG4105CVI	Transcriptional regulator
A9258_13485	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
A9258_13490	ENOG4106MZZ	glycerophosphoryl diester phosphodiesterase
A9258_13495	ENOG4105C6V	Glycerol-3-phosphate dehydrogenase
A9258_13500	ENOG4105E98	transcriptional regulator DeoR family
A9258_13505	ENOG4105CXY	transporter
A9258_13510	ENOG4105D8C	Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity)
A9258_13515	ENOG4108JQ0	Key enzyme in the regulation of glycerol uptake and metabolism (By similarity)
A9258_13520	ENOG4105HEI	LysR family (Transcriptional regulator
A9258_13540	ENOG4105CV8	reductase
A9258_13545	ENOG4105F27	Major Facilitator
A9258_13555	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
A9258_13560	ENOG4105C4M	(Ubiquinol oxidase) subunit I
A9258_13565	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
A9258_13575	ENOG4108Q2J	Inner membrane protein YebE
A9258_13590	ENOG4106428	Protein of unknown function (DUF2496)
A9258_13600	ENOG4105D2S	major facilitator superfamily
A9258_13615	ENOG4105DJ2	Major Facilitator Superfamily
A9258_13620	ENOG4105FE9	pseudouridine synthase
A9258_13625	ENOG4105D82	Glutamate dehydrogenase
A9258_13645	ENOG4105CFI	type iii restriction protein res subunit
A9258_13655	ENOG4105WWK	YheO domain protein
A9258_13660	ENOG4105CEM	UPF0597 protein
A9258_13665	ENOG4105KME	endoribonuclease L-psp
A9258_13670	ENOG4105C44	Serine transporter
A9258_13675	ENOG4108NVR	Methyl-accepting chemotaxis
A9258_13690	ENOG4105DP5	Catalyzes the biosynthesis of agmatine from arginine (By similarity)
A9258_13695	ENOG4105D42	Cleaves the N-terminal amino acid of tripeptides (By similarity)
A9258_13720	ENOG4108YYC	ycei family
A9258_13725	ENOG4105CC0	LysR family Transcriptional regulator
A9258_13735	ENOG4105CKU	formyltetrahydrofolate synthetase
A9258_13740	ENOG4105C8Q	Methyl-accepting chemotaxis
A9258_13745	ENOG4105EUJ	GTP cyclohydrolase i
A9258_13750	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
A9258_13755	ENOG4105D06	uba thif-type nad fad binding protein
A9258_13760	ENOG4105D3C	The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters (By similarity)
A9258_13765	ENOG4105CGB	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system (By similarity)
A9258_13770	ENOG4105E0C	molybdate abc transporter
A9258_13775	ENOG4108S6J	ABC transporter, periplasmic molybdate-binding protein
A9258_13780	ENOG4108ZAF	Molybdopterin
A9258_13785	ENOG4105M00	molybdopterin converting factor, subunit 1
A9258_13790	ENOG4108YXW	Together with MoaA, is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
A9258_13795	ENOG4108RIR	Molybdenum cofactor biosynthesis protein
A9258_13800	ENOG4105CUW	cytochrome C-TYPE protein
A9258_13810	ENOG4105GXZ	Ferredoxin-type protein NapH
A9258_13815	ENOG4108BGM	Quinol dehydrogenase periplasmic component
A9258_13820	ENOG4107QIW	Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity)
A9258_13830	ENOG4108ZNS	ferredoxin-type protein NapF
A9258_13835	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
A9258_13840	ENOG4105BZU	Histidine kinase
A9258_13845	ENOG4105WH1	Two component transcriptional regulator luxr family
A9258_13855	ENOG4105BZU	Histidine kinase
A9258_13865	ENOG4105CHW	UPF0052 protein
A9258_13875	ENOG4105E7A	Glutamine amidotransferase
A9258_13880	ENOG4105F55	Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate (By similarity)
A9258_13885	ENOG4107QPN	acyl-Coa dehydrogenase
A9258_13890	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
A9258_13900	ENOG4108JDX	DNA polymerase iii, epsilon subunit
A9258_13905	ENOG4108UMW	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
A9258_13910	ENOG4105D1A	Methyltransferase
A9258_13915	ENOG4108RW0	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
A9258_13920	ENOG4105E9H	Lytic Murein transglycosylase
A9258_13935	ENOG4105NAU	thioesterase Superfamily protein
A9258_13945	ENOG41060NJ	transcriptional regulator
A9258_13950	ENOG4107SC1	transglycosylase
A9258_13955	ENOG4105BZU	Histidine kinase
A9258_13960	ENOG4108WPH	sigma 54 modulation protein ribosomal protein S30EA
A9258_13985	ENOG4105CFU	surface antigen
A9258_13995	ENOG4105KQ5	peptidylprolyl cis-trans isomerase
A9258_14010	ENOG4107ZN8	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity (By similarity)
A9258_14020	ENOG4105VNH	ABC transporter solute-binding protein
A9258_14030	ENOG4108VGW	abc transporter atp-binding protein
A9258_14035	ENOG4108T9J	Cdp-alcohol phosphatidyltransferase
A9258_14040	ENOG4105CVE	Lytic murein transglycosylase
A9258_14055	ENOG4107QIX	Phosphoglucomutase (EC 5.4.2.2
A9258_14060	ENOG4107CDU	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated (By similarity)
A9258_14065	ENOG4105EV9	Alpha Beta Hydrolase
A9258_14075	ENOG4105NNH	LexA regulated protein
A9258_14080	ENOG4105MHQ	Low-potential electron donor to a number of redox enzymes (By similarity)
A9258_14090	ENOG41090R7	Ferric uptake
A9258_14095	ENOG4105CX6	glutaminyL-tRNA synthetase
A9258_14100	ENOG4105E2D	ec 3.2.1.52
A9258_14105	ENOG4105CI1	PTS System
A9258_14110	ENOG4105CKA	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion (By similarity)
A9258_14115	ENOG4105CE4	GlcNAc 6-P deacetylase
A9258_14120	ENOG4105E2R	ROK family
A9258_14125	ENOG4105DIJ	Phosphoethanolamine transferase
A9258_14130	ENOG4105CDY	transcriptional regulatory protein
A9258_14135	ENOG4105C9M	aspartyl-trna synthetase
A9258_14140	ENOG41081XQ	Conserved Protein
A9258_14145	ENOG4105DA6	Catalyzes the conversion of 5-methoxyuridine (mo5U) to uridine-5-oxyacetic acid (cmo5U) at position 34 in tRNA. May also participate in the methylation of uridine-5-oxyacetic acid (cmo5U) to uridine-5-oxyacetic acid methyl ester (mcmo5U) (By similarity)
A9258_14150	ENOG4105PFA	Catalyzes the conversion of 5-hydroxyuridine (ho5U) to 5-methoxyuridine (mo5U) at position 34 in tRNA (By similarity)
A9258_14170	ENOG4105D3R	alkyl hydroperoxide reductase
A9258_14175	ENOG4105C5Q	Transcriptional regulator
A9258_14185	ENOG4107TT5	NLP P60 protein
A9258_14195	ENOG4107RGH	Aldehyde dehydrogenase
A9258_14200	ENOG4107Z3H	Transcriptional regulator, TetR family
A9258_14220	ENOG4105C6T	cysteine synthase
A9258_14240	ENOG4105UQX	Mate efflux family protein
A9258_14260	ENOG4107SQI	penicillin amidase
A9258_14265	ENOG4105D95	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin (By similarity)
A9258_14275	ENOG4105QVC	MOSC domain-containing protein
A9258_14275	ENOG4105QVC	MOSC domain-containing protein
A9258_14280	ENOG4107SDU	Methyl-accepting chemotaxis
A9258_14285	ENOG4105D0M	Protease HtpX homolog
A9258_14290	ENOG4105E78	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity)
A9258_14295	ENOG410626R	Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity)
A9258_14300	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
A9258_14305	ENOG4105CZF	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism (By similarity)
A9258_14325	ENOG4105C5S	asparaginyl-tRNA synthetase
A9258_14330	ENOG4105DS2	Anaerobic c4-dicarboxylate transporter
A9258_14345	ENOG4105CEE	C4-dicarboxylate transporter
A9258_14360	ENOG4105KUZ	arsenate reductase
A9258_14365	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
A9258_14375	ENOG4105C3N	Participates in control of cell volume in low-osmolarity conditions (By similarity)
A9258_14395	ENOG410829K	Lysine exporter protein (Lyse ygga)
A9258_14400	ENOG4108NVR	Methyl-accepting chemotaxis
A9258_14405	ENOG4105RX8	Protein of unknown function (DUF1523)
A9258_14420	ENOG4105DU0	nucleoside hydrolase
A9258_14425	ENOG4105D3G	Pseudouridine synthase
A9258_14430	ENOG4107SXA	Phosphorylase
A9258_14435	ENOG4105C0A	alcohol dehydrogenase
A9258_14515	ENOG4105YRI	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
A9258_14520	ENOG4105K4T	epimerase
A9258_14525	ENOG4105VDB	UPF0125 protein
A9258_14530	ENOG4108Z1B	Cyclase dehydrase
A9258_14535	ENOG4108UH4	Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity)
A9258_14620	ENOG4105EFV	Major head subunit
A9258_14625	ENOG4108TVE	i protein
A9258_14645	ENOG4105QIB	mu-like prophage Flumu protein gp29
A9258_14650	ENOG4105CF2	Mu-like prophage FluMu protein GP28
A9258_14655	ENOG4108Z6H	mu-like prophage Flumu protein gp27
A9258_14765	ENOG4108F3G	Type I restriction-modification system, R subunit
A9258_14805	ENOG4105W8I	Transcriptional regulator
A9258_14815	ENOG4105BZC	d-serine deaminase
A9258_14820	ENOG4108HMX	isocitrate dehydrogenase (NADP)
A9258_14825	ENOG4106R3P	AraC family transcriptional regulator
A9258_14830	ENOG4105EIP	mannose-6-phosphate isomerase
A9258_14840	ENOG4105DM4	PTS System
A9258_14850	ENOG4105C87	Aminotransferase class I and II
A9258_14855	ENOG4105CI1	PTS System
A9258_14860	ENOG4107P2S	Transcriptional regulator
A9258_14875	ENOG4105KEG	ribosomal-protein-alanine acetyltransferase
A9258_14895	ENOG4105DM4	PTS System
A9258_14900	ENOG4105CXY	transporter
A9258_14905	ENOG4108YRF	PTS System
A9258_14915	ENOG4108R99	pseudouridine synthase
A9258_14925	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
A9258_14930	ENOG41075W9	High frequency lysogenization protein HflD homolog
A9258_14935	ENOG4107QTF	adenylosuccinate lyase
A9258_14940	ENOG4105EZE	Cupin 4 family protein
A9258_14950	ENOG4108YYD	acetyltransferase
A9258_14965	ENOG4108S7T	Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) (By similarity)
A9258_14985	ENOG4105M2J	Glutaredoxin
A9258_14990	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
A9258_14995	ENOG410903C	(LipO)protein
A9258_15000	ENOG4105KWW	Biogenesis protein
A9258_15005	ENOG4105KWW	Biogenesis protein
A9258_15010	ENOG4107QX9	Thiol disulfide interChange protein
A9258_15015	ENOG4105DA4	cytochrome c-type biogenesis protein
A9258_15020	ENOG4108ZKK	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH (By similarity)
A9258_15025	ENOG4105X3C	heme exporter protein
A9258_15030	ENOG41060IM	Heme exporter protein
A9258_15035	ENOG4105CA5	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes (By similarity)
A9258_15050	ENOG4108V3W	Chemotaxis protein, CheW
A9258_15060	ENOG4107QJE	Chromosome Partitioning Protein
A9258_15065	ENOG4108SEK	ompa motb domain protein
A9258_15070	ENOG4105E14	MotA TolQ exbB proton channel
A9258_15075	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
A9258_15080	ENOG4105CBS	Chea signal transduction histidine kinase
A9258_15085	ENOG4108KCC	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P) (By similarity)
A9258_15090	ENOG4108VYJ	response regulator receiver protein
A9258_15095	ENOG4105DN4	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
A9258_15105	ENOG4105FZW	flagellar biosynthesis regulator FlhF
A9258_15110	ENOG4105D7B	Flagellar biosynthesis protein flha
A9258_15115	ENOG4105D00	flagellar biosynthetic protein flhB
A9258_15120	ENOG4105D19	Role in flagellar biosynthesis (By similarity)
A9258_15125	ENOG4105VS8	Flagellar biosynthetic protein fliq
A9258_15130	ENOG4105CN7	Flagellar biosynthetic protein FliP
A9258_15135	ENOG4105VTB	flagellar biosynthesis protein fliO
A9258_15140	ENOG4105DD5	Flagellar motor switch protein
A9258_15145	ENOG4105D24	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
A9258_15165	ENOG4108JIR	Flagellum-specific ATP synthase
A9258_15175	ENOG4105CS3	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
A9258_15180	ENOG4105C1F	The M ring may be actively involved in energy transduction (By similarity)
A9258_15185	ENOG4105VQ0	flagellar hook-basal body complex protein fliE
A9258_15195	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
A9258_15200	ENOG4105CBM	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 (By similarity)
A9258_15210	ENOG4105EUK	rtx toxin RtxA
A9258_15225	ENOG4108JJA	ABC, transporter
A9258_15230	ENOG4105C42	Type I secretion membrane fusion protein (HlyD
A9258_15235	ENOG4108JJA	ABC, transporter
A9258_15240	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
A9258_15255	ENOG4106KNT	transcriptional regulator
A9258_15260	ENOG4105CA9	Pyruvate kinase
A9258_15270	ENOG4105BZS	acriflavin resistance protein
A9258_15275	ENOG4107QPN	acyl-Coa dehydrogenase
A9258_15285	ENOG4107SSZ	Phosphatase
A9258_15300	ENOG4108NF7	phage-type endonuclease
A9258_15325	ENOG4108ZQS	transposase
A9258_15330	ENOG4108MVM	Transposase
A9258_15360	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
A9258_15380	ENOG4105CVR	type I restriction-modification system
A9258_15400	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
A9258_15405	ENOG4107UNZ	domain protein
A9258_15425	ENOG4107QKC	Oxidoreductase alpha (molybdopterin) subunit
A9258_15430	ENOG4107H9G	Necessary for formate dehydrogenase activity (By similarity)
A9258_15435	ENOG4105CBN	LysR family transcriptional regulator
A9258_15455	ENOG4105KNY	Microcompartments protein
A9258_15460	ENOG4105KNY	Microcompartments protein
A9258_15465	ENOG4105KNY	Microcompartments protein
A9258_15470	ENOG4108EKI	Dehydrogenase
A9258_15480	ENOG4108EKI	Dehydrogenase
A9258_15485	ENOG4105C6N	Formate acetyltransferase
A9258_15490	ENOG4105F1A	Pyruvate formate-lyase
A9258_15495	ENOG4105KNY	Microcompartments protein
A9258_15500	ENOG4108VPX	Involved in 1,2-propanediol (1,2-PD) degradation by catalyzing the conversion of propanoyl-CoA to propanoyl-phosphate (By similarity)
A9258_15545	ENOG4108R66	Conserved Protein
A9258_15550	ENOG4107RJ1	sodium solute
A9258_15560	ENOG4105C9S	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P) (By similarity)
A9258_15565	ENOG4105QEK	Transcriptional regulator
A9258_15570	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
A9258_15575	ENOG4105C1X	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity (By similarity)
A9258_15580	ENOG4105E98	transcriptional regulator DeoR family
A9258_15585	ENOG4105EDR	glucose galactose transporter
A9258_15590	ENOG4105EHF	Converts the aldose L-fucose into the corresponding ketose L-fuculose (By similarity)
A9258_15595	ENOG4105CMG	Carbohydrate kinase
A9258_15605	ENOG4105NWF	RbsD or FucU transport
A9258_15615	ENOG4108JQ5	ABC transporter
A9258_15620	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
A9258_15630	ENOG4105DEF	Extracellular solute-binding protein, family 5
A9258_15640	ENOG4107N1Q	ErfK YbiS YcfS YnhG family protein
A9258_15655	ENOG4105EBA	Specifically methylates the adenine in position 1618 of 23S rRNA (By similarity)
A9258_15660	ENOG4107TT5	NLP P60 protein
A9258_15670	ENOG4107QR8	Thioredoxin
A9258_15680	ENOG4105C66	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity)
A9258_15685	ENOG4105CIY	formyltetrahydrofolate deformylase
A9258_15695	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
A9258_15710	ENOG4108VC8	Peptidase family M23
A9258_15720	ENOG4105E4C	Lytic transglycosylase catalytic
A9258_15725	ENOG4105D8C	Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity)
A9258_15730	ENOG4105NHU	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group (By similarity)
A9258_15740	ENOG4105EP9	oxidoreductase
A9258_15760	ENOG4105CCT	upf0313 protein
A9258_15770	ENOG4105BZS	acriflavin resistance protein
A9258_15775	ENOG4105J12	Multidrug resistance protein mdtN
A9258_15780	ENOG4105BZU	Histidine kinase
A9258_15785	ENOG4105D78	K07001 NTE family protein
A9258_15790	ENOG4105C8J	)-transporter
A9258_15805	ENOG4105UYK	outer membrane protein a
A9258_15810	ENOG4105UYK	outer membrane protein a
A9258_15815	ENOG4105UYK	outer membrane protein a
A9258_15820	ENOG4107R1I	NAD-dependent malic enzyme
A9258_15825	ENOG4105ECQ	AraC Family Transcriptional Regulator
A9258_15830	ENOG4105UQX	Mate efflux family protein
A9258_15835	ENOG4105RKX	Protein of unknown function (DUF2498)
A9258_15840	ENOG4105BZU	Histidine kinase
A9258_15845	ENOG4105C2W	permease
A9258_15850	ENOG4108KMH	lipoate-protein ligase a
A9258_15855	ENOG4105BZG	amino acid carrier protein
A9258_15880	ENOG4105PTV	Nudix Hydrolase
A9258_15900	ENOG4105CJ1	ABC, transporter
A9258_15905	ENOG4108V1T	peptidylprolyl cis-trans isomerase
A9258_15910	ENOG4106N3A	copper homeostasis protein cutc
A9258_15925	ENOG4105ERG	peptidase m48, ste24p
A9258_15935	ENOG4105BZU	Histidine kinase
A9258_15940	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
A9258_15945	ENOG4108ZI4	Glyoxalase Bleomycin resistance protein (Dioxygenase
A9258_15950	ENOG4105C04	l-carnitine dehydratase bile acid-inducible protein F
A9258_15955	ENOG4105C1G	acyl-Coa dehydrogenase
A9258_15960	ENOG4108JU9	GAF modulated sigma54 specific transcriptional regulator Fis family
A9258_15965	ENOG4105C26	Dehydrogenase
A9258_15975	ENOG4108IPJ	Membrane
A9258_15980	ENOG4106YYS	transcriptional regulatory protein
A9258_15985	ENOG4105CEQ	signal transduction histidine kinase regulating citrate malate metabolism
A9258_15990	ENOG4107R1I	NAD-dependent malic enzyme
A9258_15995	ENOG4105D2K	citrate carrier protein
A9258_16000	ENOG4108US0	Transcription regulator that can specifically activate or repress expression of target genes (By similarity)
A9258_16005	ENOG4105J12	Multidrug resistance protein mdtN
A9258_16035	ENOG4108RDD	Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine (By similarity)
A9258_16040	ENOG4105CJD	(Anaerobic) ribonucleoside-triphosphate reductase
A9258_16050	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
A9258_16060	ENOG4105CDB	Required for chromosome condensation and partitioning (By similarity)
A9258_16065	ENOG4105EXN	Sulfate transport protein CysZ
A9258_16070	ENOG4105EN6	Membrane
A9258_16080	ENOG4105EAQ	(twin-arginine translocation) pathway signal
A9258_16085	ENOG4105DIT	ErfK YbiS YcfS YnhG family protein
A9258_16115	ENOG4107T9C	Alpha amylase catalytic region
A9258_16150	ENOG4105BZU	Histidine kinase
A9258_16155	ENOG4105D3U	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
A9258_16160	ENOG4105C9K	Endothelin-converting enzyme 1
A9258_16170	ENOG4105C5H	ABC transporter
A9258_16175	ENOG4105KNA	-acetyltransferase
A9258_16180	ENOG4105DVH	amino acid
A9258_16185	ENOG4105EXG	Transcriptional regulator
A9258_16195	ENOG4105C44	Serine transporter
A9258_16200	ENOG4105EQ2	LysR family Transcriptional regulator
A9258_16210	ENOG4107XGF	functions in a salvage pathway. Uses pyridoxamine (By similarity)
A9258_16215	ENOG4105CXN	decarboxylase
A9258_16220	ENOG4105D5Q	Arginine ornithine antiporter
A9258_16225	ENOG4108M3R	transcriptional activator CadC
A9258_16230	ENOG4107QM9	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA (By similarity)
A9258_16235	ENOG4105C0B	DNA polymerase III (alpha subunit)
A9258_16240	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
A9258_16245	ENOG4105D0V	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
A9258_16250	ENOG4105DAF	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
A9258_16255	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
A9258_16260	ENOG4105D7M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
A9258_16265	ENOG4108RFI	Molecular chaperone that interacts specifically with outer membrane proteins, thus maintaining the solubility of early folding intermediates during passage through the periplasm (By similarity)
A9258_16275	ENOG4105DZP	Membrane-associated zinc metalloprotease
A9258_16280	ENOG4105CEA	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity)
A9258_16285	ENOG4105KNE	Phosphatidate cytidylyltransferase
A9258_16290	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
A9258_16295	ENOG4108VCV	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity)
A9258_16300	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
A9258_16305	ENOG4105CU7	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity)
A9258_16310	ENOG4105CE9	30S ribosomal protein S2
A9258_16315	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
A9258_16320	ENOG4105E1P	Modifies, by uridylylation or deuridylylation the PII (GlnB) regulatory protein (By similarity)
A9258_16325	ENOG4105DMJ	Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate (By similarity)
A9258_16330	ENOG4108T8E	UPF0325 protein
A9258_16335	ENOG4105CI1	PTS System
A9258_16340	ENOG4107W52	maltose operon periplasmic protein
A9258_16345	ENOG4108KDD	Involved in the transport of maltose and maltodextrins (By similarity)
A9258_16350	ENOG4105QDK	Flavodoxin
A9258_16355	ENOG4105DR9	pseudouridine synthase
A9258_16360	ENOG4105WP7	tRNA pseudouridine synthase C
A9258_16385	ENOG4105EXF	Zn-ribbon-containing, possibly nucleic-acid-binding protein
A9258_16390	ENOG4108T6E	Interacts with the SecY protein in vivo. May bind preferentially to an uncomplexed state of SecY, thus functioning either as a chelating agent for excess SecY in the cell or as a regulatory factor that negatively controls the translocase function (By similarity)
A9258_16395	ENOG4107R1K	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) (By similarity)
A9258_16405	ENOG4105BZU	Histidine kinase
A9258_16410	ENOG4105EWT	decarboxylase family
A9258_16415	ENOG4105CIQ	May have a role in processing of nucleic acids. It is probably not an exonuclease
A9258_16420	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
A9258_16430	ENOG4105EZ6	Catalyzes the 2'-O-methylation at nucleotide C2498 in 23S rRNA (By similarity)
A9258_16435	ENOG4105M08	Membrane
A9258_16445	ENOG4105ETT	transcriptional Regulator, LysR family
A9258_16450	ENOG4105C8Q	Methyl-accepting chemotaxis
A9258_16455	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
A9258_16470	ENOG4105CJ2	(LipO)protein
A9258_16475	ENOG4105D26	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. The first step is catalyzed by NqrF, which accepts electrons from NADH and reduces ubiquinone-1 to ubisemiquinone by a one-electron transfer pathway (By similarity)
A9258_16480	ENOG4108IUB	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
A9258_16485	ENOG4105F5D	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
A9258_16490	ENOG4106I92	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
A9258_16495	ENOG4108J5C	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
A9258_16500	ENOG4105DWQ	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
A9258_16505	ENOG4105M85	Bola protein
A9258_16510	ENOG4105D8J	Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle (By similarity)
A9258_16520	ENOG4108R5K	PPIases accelerate the folding of proteins (By similarity)
A9258_16530	ENOG4105EYM	Major Facilitator superfamily
A9258_16535	ENOG4105DRB	nucleoside-specific channel-forming protein
A9258_16540	ENOG4108VPT	UPF0234 protein
A9258_16545	ENOG4108JZF	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity)
A9258_16550	ENOG4107S0N	DJ-1 family
A9258_16555	ENOG4105C7K	acetolactate synthase
A9258_16590	ENOG4108WC9	type VI secretion system effector, hcp1 family
A9258_16595	ENOG4105VJY	transcriptional regulator
A9258_16605	ENOG4105DRC	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity)
A9258_16610	ENOG4105CMR	udp-glucose 4-epimerase
A9258_16620	ENOG4105EJ7	Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O (By similarity)
A9258_16625	ENOG4108RMU	ferritin dps family protein
A9258_16650	ENOG4105CV9	cyclopropane-fatty-acyl-phospholipid synthase
A9258_16665	ENOG4105EMU	Dehydrogenase
A9258_16675	ENOG4105CVP	deoxyribo-dipyrimidine photolyase
A9258_16680	ENOG4108XDN	Transcriptional regulator
A9258_16685	ENOG4107SEY	Conserved Protein
A9258_16715	ENOG4105CQC	Prephenate dehydratase
A9258_16745	ENOG4108NF7	phage-type endonuclease
A9258_16785	ENOG4105W5Q	DNA repair protein (RadC
A9258_16795	ENOG4105EIZ	Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity)
A9258_16800	ENOG4105FD2	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) (By similarity)
A9258_16815	ENOG4107ZIF	6-carboxy-5,6,7,8-tetrahydropterin synthase
A9258_16830	ENOG4105C9U	ATP-dependent DNA helicase RecQ
A9258_16850	ENOG4105C9U	ATP-dependent DNA helicase RecQ
A9258_16855	ENOG4105BZK	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair (By similarity)
A9258_16880	ENOG4107ZSV	Receptor
A9258_16905	ENOG4108JUA	Transcriptional regulator
A9258_16925	ENOG4105EHG	Permease protein
A9258_16930	ENOG4108W0P	ABC transporter
A9258_16940	ENOG4105DVA	methyltransferase
A9258_16965	ENOG4105D8V	Glucose sorbosone dehydrogenase
A9258_16975	ENOG4105C8Q	Methyl-accepting chemotaxis
A9258_16980	ENOG4105J5J	Outer membrane porin
A9258_16985	ENOG4105E1F	short-chain dehydrogenase reductase
A9258_17010	ENOG4105CTD	carboxy-peptidase
A9258_17025	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
A9258_17030	ENOG4105CFP	Peptidase U32
A9258_17035	ENOG4105N14	lysine exporter protein LysE YggA
A9258_17045	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
A9258_17050	ENOG4105C8Q	Methyl-accepting chemotaxis
A9258_17055	ENOG4108VYJ	response regulator receiver protein
A9258_17065	ENOG4105CBS	Chea signal transduction histidine kinase
A9258_17075	ENOG4108V3W	Chemotaxis protein, CheW
A9258_17080	ENOG4105C8Q	Methyl-accepting chemotaxis
A9258_17085	ENOG4105BZU	Histidine kinase
A9258_17090	ENOG4108Z4W	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis (By similarity)
A9258_17095	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
A9258_17100	ENOG4105C9B	Cysteine desulfurase
A9258_17130	ENOG4108NJZ	Sensory box GGDEF EAL domain protein
A9258_17135	ENOG4105CFP	Peptidase U32
A9258_17140	ENOG4105K5D	4fe-4S ferredoxin iroN-sulfur binding
A9258_17145	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
A9258_17150	ENOG4105CDU	Replicative dna helicase
A9258_17160	ENOG4105BZU	Histidine kinase
A9258_17165	ENOG4105CGH	5'-nucleotidase
A9258_17185	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
A9258_17190	ENOG4108V1T	peptidylprolyl cis-trans isomerase
A9258_17200	ENOG4105VRX	Protein slyX homolog
A9258_17205	ENOG4108YZY	peptidylprolyl cis-trans isomerase
A9258_17210	ENOG4105VKU	nucleicacid-binding protein
A9258_17220	ENOG4107R88	Chemotaxis protein (CheV)
A9258_17225	ENOG4105DNZ	Alpha Beta Hydrolase
A9258_17235	ENOG4105YP7	UPF0270 protein
A9258_17240	ENOG4105C6Y	Udp-glucose 6-dehydrogenase
A9258_17245	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
A9258_17250	ENOG4105CKK	Glycosyl transferase, family 2
A9258_17255	ENOG4108I2E	Bifunctional enzyme that catalyzes the oxidative decarboxylation of UDP-glucuronic acid (UDP-GlcUA) to UDP-4-keto- arabinose (UDP-Ara4O) and the addition of a formyl group to UDP-4- amino-4-deoxy-L-arabinose (UDP-L-Ara4N) to form UDP-L-4-formamido- arabinose (UDP-L-Ara4FN). The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides (By similarity)
A9258_17260	ENOG4105F73	Catalyzes the deformylation of 4-deoxy-4-formamido-L- arabinose-phosphoundecaprenol to 4-amino-4-deoxy-L-arabinose- phosphoundecaprenol. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides (By similarity)
A9258_17265	ENOG4105SA9	Catalyzes the transfer of the L-Ara4N moiety of the glycolipid undecaprenyl phosphate-alpha-L-Ara4N to lipid A. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides (By similarity)
A9258_17270	ENOG41060GT	Translocates 4-amino-4-deoxy-L-arabinose- phosphoundecaprenol (alpha-L-Ara4N-phosphoundecaprenol) from the cytoplasmic to the periplasmic side of the inner membrane (By similarity)
A9258_17275	ENOG4105PE8	Translocates 4-amino-4-deoxy-L-arabinose- phosphoundecaprenol (alpha-L-Ara4N-phosphoundecaprenol) from the cytoplasmic to the periplasmic side of the inner membrane (By similarity)
A9258_17280	ENOG4105CJE	phosphoribulokinase (EC 2.7.1.19)
A9258_17295	ENOG4108UKZ	OsmC family
A9258_17300	ENOG4107RYR	Transcriptional regulator, Crp Fnr family
A9258_17305	ENOG4105DHI	Methyltransferase
A9258_17310	ENOG4108M1A	Chitin-binding protein
A9258_17315	ENOG4108MA4	Peptidase M66
A9258_17325	ENOG4105BZU	Histidine kinase
A9258_17335	ENOG4105VMP	Transcriptional regulator
A9258_17340	ENOG4105D8G	Major Facilitator superfamily
A9258_17345	ENOG4105D05	Receptor
A9258_17365	ENOG4105PYN	Pyridoxamine 5-phosphate oxidase-related
A9258_17370	ENOG41090JE	Utilization Protein
A9258_17380	ENOG4105EHG	Permease protein
A9258_17410	ENOG4105D9N	nucleoside
A9258_17415	ENOG4107U5R	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate (By similarity)
A9258_17435	ENOG4105E4C	Lytic transglycosylase catalytic
A9258_17440	ENOG4105DUF	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively (By similarity)
A9258_17455	ENOG4105C5H	ABC transporter
A9258_17465	ENOG4105C7N	Xanthine uracil vitamin C permease
A9258_17470	ENOG41066UG	Regulatory DnaK co-chaperone. Direct interaction between DnaK and DjlA is needed for the induction of the wcaABCDE operon, involved in the synthesis of a colanic acid polysaccharide capsule, possibly through activation of the RcsB RcsC phosphotransfer signaling pathway. The colanic acid capsule may help the bacterium survive conditions outside the host (By similarity)
A9258_17475	ENOG4108S0S	Nucleotidyl transferase
A9258_17480	ENOG4105EHM	Aminoglycoside phosphotransferase
A9258_17485	ENOG4105E7H	involved in the assembly of LPS in the outer leaflet of the outer membrane. Determines N-hexane tolerance and is involved in outer membrane permeability. Essential for envelope biogenesis (By similarity)
A9258_17495	ENOG4105CEZ	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) (By similarity)
A9258_17500	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
A9258_17505	ENOG4105NWN	ApaG protein
A9258_17510	ENOG4105DDT	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP (By similarity)
A9258_17520	ENOG4105DEN	Luciferase family
A9258_17525	ENOG4108ESY	Metal dependent phosphohydrolase
A9258_17540	ENOG4105CEY	Amp-dependent synthetase and ligase
A9258_17545	ENOG4105DWD	nucleoside recognition domain protein
A9258_17550	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
A9258_17555	ENOG4105K46	50S ribosomal protein l27
A9258_17565	ENOG4105EAH	synthase
A9258_17575	ENOG4105EPW	hflc protein
A9258_17580	ENOG4107QJR	hflk protein
A9258_17585	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
A9258_17590	ENOG4105KW8	RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity)
A9258_17595	ENOG4105DKX	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity)
A9258_17600	ENOG4105DC6	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity)
A9258_17605	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
A9258_17610	ENOG4105K8N	protein family UPF0079, ATPase
A9258_17615	ENOG4105DR1	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)
A9258_17620	ENOG4105EH2	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity)
A9258_17640	ENOG4108JEI	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity)
A9258_17645	ENOG4108UMI	ABC transporter, permease
A9258_17650	ENOG4105D01	(LipO)protein
A9258_17655	ENOG4105MDZ	Transcriptional activator rfaH
A9258_17660	ENOG4108N3W	hemolysin secretion protein
A9258_17665	ENOG4105BZU	Histidine kinase
A9258_17670	ENOG4105BZU	Histidine kinase
A9258_17680	ENOG4105C4Q	deoxyguanosinetriphosphate triphosphohydrolase-like protein
A9258_17685	ENOG4105BZU	Histidine kinase
A9258_17705	ENOG4106173	Uncharacterized protein conserved in bacteria (DUF2057)
A9258_17710	ENOG4105EXG	Transcriptional regulator
A9258_17720	ENOG4107QWK	SAICAR synthetase
A9258_17725	ENOG4107EG0	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
A9258_17730	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
A9258_17735	ENOG4105RH4	Glycine cleavage system transcriptional repressor
A9258_17740	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
A9258_17745	ENOG4105XWI	UPF0304 protein
A9258_17750	ENOG4105PQ6	UPF0208 membrane protein
A9258_17755	ENOG4105C6H	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity)
A9258_17760	ENOG4105C6K	Malic enzyme
A9258_17765	ENOG4108ZP8	Acetolactate synthase small subunit
A9258_17770	ENOG4105C7K	acetolactate synthase
A9258_17780	ENOG4105YVM	Phosphoesterase, PA-phosphatase related
A9258_17790	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
A9258_17800	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
A9258_17805	ENOG4105MQS	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
A9258_17820	ENOG4105DP9	ABC transporter
A9258_17825	ENOG4106SMU	thiamine transporter membrane protein
A9258_17830	ENOG4107T0D	ABC, transporter
A9258_17835	ENOG4108IAB	Phoh family
A9258_17845	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
A9258_17875	ENOG4105BZK	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair (By similarity)
A9258_17880	ENOG4105D3G	Pseudouridine synthase
A9258_17890	ENOG4105BZU	Histidine kinase
A9258_17900	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
A9258_17905	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
A9258_17910	ENOG4107QI1	Mate efflux family protein
A9258_17915	ENOG4108YH1	overproduction of this protein in Escherichia coli inhibits the F plasmid-mediated exclusion of bacteriophage T7
A9258_17920	ENOG4108IJ0	Aspartate ammonia-lyase
A9258_17925	ENOG4105DS2	Anaerobic c4-dicarboxylate transporter
A9258_17935	ENOG4105EV4	Multidrug resistance protein mdtH
A9258_17955	ENOG4105D9U	N-acetyltransferase
A9258_17965	ENOG4105D9R	oxidoreductase
A9258_17975	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
A9258_17980	ENOG4105CSA	Coproporphyrinogen iii oxidase
A9258_17990	ENOG4105NAE	bifunctional deaminase-reductase domain protein
A9258_18000	ENOG4105DC1	bifunctional purine biosynthesis protein purh
A9258_18005	ENOG4105C12	Phosphoribosylglycinamide synthetase
A9258_18035	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
A9258_18040	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
A9258_18045	ENOG4105KTH	gatB Yqey
A9258_18050	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
A9258_18060	ENOG4108K5P	(LipO)protein
A9258_18065	ENOG4108UM1	dedA family
A9258_18070	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
A9258_18075	ENOG4105CV2	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates (By similarity)
A9258_18080	ENOG4106NZV	Responsible for synthesis of pseudouridine from uracil- 13 in transfer RNAs (By similarity)
A9258_18085	ENOG4108UH8	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (By similarity)
A9258_18090	ENOG4105CE5	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) (By similarity)
A9258_18095	ENOG4105XX3	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity)
A9258_18100	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
A9258_18105	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
A9258_18110	ENOG4105DXN	mazG family
A9258_18115	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
A9258_18120	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
A9258_18125	ENOG4105BZU	Histidine kinase
A9258_18130	ENOG4108W15	Protein of unknown function (DUF1456)
A9258_18135	ENOG4108VBV	N-Acetylmuramoyl-L-alanine amidase
A9258_18140	ENOG4105E98	transcriptional regulator DeoR family
A9258_18145	ENOG4105C6Q	that is required for full activity and stability of the Y subunit. Could have a chaperone-like function for the proper and stable folding of
A9258_18150	ENOG4105E70	isomerase
A9258_18155	ENOG4108RG5	PTS system N-acetylgalactosamine-specific transporter subunit IIB
A9258_18165	ENOG4105F3R	pts system mannose fructose sorbose family iid
A9258_18170	ENOG4108YTN	IIa component
A9258_18175	ENOG4105CE4	GlcNAc 6-P deacetylase
A9258_18180	ENOG4105D2N	Aldolase
A9258_18190	ENOG4105CSZ	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate (By similarity)
A9258_18195	ENOG41071DT	Involved in DNA repair and RecF pathway recombination (By similarity)
A9258_18210	ENOG4105C3F	Signal peptidase i
A9258_18215	ENOG4105C4S	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity)
A9258_18230	ENOG41069PW	sigma-e factor negative regulatory protein
A9258_18235	ENOG4105EMN	RNA polymerase sigma factor
A9258_18240	ENOG4108IYU	L-aspartate oxidase
A9258_18250	ENOG4105Y75	tpr repeat protein
A9258_18255	ENOG4106XY2	Folate-binding protein involved in regulating the level of ATP-DnaA and in the modification of some tRNAs. It is probably a key factor in regulatory networks that act via tRNA modification, such as initiation of chromosomal replication (By similarity)
A9258_18280	ENOG4105CSG	Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps (By similarity)
A9258_18290	ENOG4105CJP	fad dependent oxidoreductase
A9258_18295	ENOG4105D2N	Aldolase
A9258_18300	ENOG4105BZA	Phosphoglycerate kinase
A9258_18305	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
A9258_18310	ENOG4105DKQ	ROK family
A9258_18315	ENOG4105CFZ	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III (By similarity)
A9258_18320	ENOG4105E09	nadh pyrophosphatase
A9258_18325	ENOG4105C26	Dehydrogenase
A9258_18330	ENOG4106MWK	domain protein
A9258_18335	ENOG4105EYW	Ion transport protein
A9258_18340	ENOG4105C8Q	Methyl-accepting chemotaxis
A9258_18350	ENOG4105CE6	Adenylation and deadenylation of glutamate--ammonia ligase (By similarity)
A9258_18375	ENOG4108IYI	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine (By similarity)
A9258_18380	ENOG4105E5Q	amino acid AbC transporter
A9258_18385	ENOG4105E5Q	amino acid AbC transporter
A9258_18390	ENOG4105CDA	abc transporter atp-binding protein
A9258_18395	ENOG4105CT1	(ABC) transporter
A9258_18400	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
A9258_18405	ENOG4105DJY	efflux transporter, rnd family, mfp subunit
A9258_18410	ENOG4105E3W	Two component transcriptional regulator (Winged helix family
A9258_18415	ENOG4105E0F	Histidine kinase
A9258_18455	ENOG4105EA8	2-Nitropropane dioxygenase
A9258_18480	ENOG4105CA0	peroxidase
A9258_18485	ENOG4107V4F	S-adenosyl-l-methionine hydroxide adenosyltransferase
A9258_18505	ENOG4105C1J	atp-dependent rna helicase
A9258_18515	ENOG4107YH7	Beta-lactamase (EC 3.5.2.6)
A9258_18520	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
A9258_18525	ENOG4105DWY	Agmatine deiminase
A9258_18540	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
A9258_18545	ENOG4108MJ3	acetyltransferase
A9258_18570	ENOG4105BZU	Histidine kinase
A9258_18575	ENOG4105BZU	Histidine kinase
A9258_18585	ENOG4107R4Q	Functions as an ATPase. May play a role in metal insertion (metal-chelatase) or as a chaperone (By similarity)
A9258_18595	ENOG41080E2	ribosomal-protein-alanine acetyltransferase
A9258_18605	ENOG4108IQE	Amp-dependent synthetase and ligase
A9258_18615	ENOG4105D9M	gamma-glutamylcysteine synthetase
A9258_18625	ENOG4105W39	Membrane
A9258_18645	ENOG4105DP0	ferredoxin-NADP reductase
A9258_18650	ENOG4105K9Q	Binds to the 23S rRNA (By similarity)
A9258_18655	ENOG4105VH8	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity)
A9258_18660	ENOG4108ZDX	Binds together with S18 to 16S ribosomal RNA (By similarity)
A9258_18665	ENOG4105C56	H( )-stimulated, divalent metal cation uptake system (By similarity)
A9258_18695	ENOG4105C2N	RNA methyltransferase TrmH family group 3
A9258_18700	ENOG4105C40	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity)
A9258_18705	ENOG4106TD9	Diguanylate cyclase
A9258_18710	ENOG4106762	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD) (By similarity)
A9258_18720	ENOG4108YZA	Nitrogen regulatory protein pii
A9258_18725	ENOG4105C4K	Nad synthetase
A9258_18785	ENOG4105C48	Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) (By similarity)
A9258_18790	ENOG41090X3	Peptidyl-prolyl cis-trans isomerase
A9258_18795	ENOG4105M02	This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity)
A9258_18800	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
A9258_18805	ENOG4105DTN	riboflavin biosynthesis protein ribF
A9258_18810	ENOG4105CJR	Integral membrane protein (MviN
A9258_18815	ENOG4105KQV	Binds directly to 16S ribosomal RNA (By similarity)
A9258_18820	ENOG41080HT	Transcriptional regulator, arsr family
A9258_18825	ENOG41063Z6	transcriptional regulator, lysR family
A9258_18835	ENOG4105DRC	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity)
A9258_18840	ENOG4105C0V	Provides the sole de novo source of dTMP for DNA biosynthesis (By similarity)
A9258_18845	ENOG4105C3B	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity)
A9258_18850	ENOG4108HRM	phosphoenolpyruvate--protein phosphotransferase
A9258_18855	ENOG4105EJF	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity)
A9258_18860	ENOG4105IRT	Sequence-specific endonuclease that cleaves unmethylated GATC sequences. It is involved in DNA mismatch repair (By similarity)
A9258_18870	ENOG4108YY1	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity)
A9258_18875	ENOG4105D6X	Specifically methylates guanosine-37 in various tRNAs (By similarity)
A9258_18880	ENOG4108ZR6	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity)
A9258_18885	ENOG4105K5M	30s ribosomal protein S16
A9258_18890	ENOG4105CB9	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
A9258_18895	ENOG4106KVJ	cytochrome C assembly protein
A9258_18900	ENOG4108JU6	CBS domain protein
A9258_18910	ENOG4105CJJ	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity)
A9258_18915	ENOG4108UV7	flagellar protein motX
A9258_18920	ENOG4105C80	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
A9258_18925	ENOG4105DMR	ABC, transporter
A9258_18930	ENOG4105GBT	ABC transporter
A9258_18935	ENOG4106PMH	Extracellular solute-binding protein family 3
A9258_18940	ENOG4105E5Z	arginine transporter ATP-binding subunit
A9258_18945	ENOG410682Y	Regulates arginine biosynthesis genes (By similarity)
A9258_18950	ENOG4105EZR	dyp-type peroxidase family protein
A9258_18955	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
A9258_18970	ENOG4108YZA	Nitrogen regulatory protein pii
A9258_18975	ENOG4108YZN	class I peptide chain release factor
A9258_18985	ENOG4105D9N	nucleoside
A9258_18990	ENOG4105HEI	LysR family (Transcriptional regulator
A9258_19005	ENOG4105BZW	Glycerate kinase
A9258_19010	ENOG4107QQ0	gntp family
A9258_19015	ENOG4108IXP	Carbohydrate diacid transcriptional activator CdaR
A9258_19020	ENOG4105XTV	UPF0231 protein
A9258_19035	ENOG4107RHT	methyl-accepting chemotaxis sensory transducer with Pas Pac sensor
A9258_19040	ENOG4108QYW	Bacterial hemolysins are exotoxins that attack blood cell membranes and cause cell rupture. Beta-hemolysin is a phospholipase C with specific activity toward sphingomyelins. Has a high specificity for sphingomyelin, hydrolyzes lysophosphatidylcholine at a much lower rate, but has no activity towards phosphatidylcholine, phosphatidylethanolamine, or phosphatidylserine (By similarity)
A9258_19055	ENOG4105C1J	atp-dependent rna helicase
A9258_19065	ENOG4108V1J	Has antioxidant activity. Could remove peroxides or H(2)O(2) (By similarity)
A9258_19095	ENOG4105CGF	Aromatic amino acid aminotransferase
A9258_19110	ENOG41076CZ	activating enzyme
A9258_19115	ENOG4105G0K	glycine radical enzyme YjjI family
A9258_19135	ENOG4107RE3	peptidase, S41
A9258_19165	ENOG4108N3W	hemolysin secretion protein
A9258_19170	ENOG4108M1A	Chitin-binding protein
A9258_19175	ENOG4107R11	Transcriptional regulator
A9258_19180	ENOG4108IJ6	ABC transporter
A9258_19185	ENOG4105ECW	sulfate abc transporter
A9258_19190	ENOG4108I5D	sulfate abc transporter
A9258_19200	ENOG4105DE7	Sulfate ABC transporter periplasmic sulfate-binding protein
A9258_19205	ENOG4107PU6	Membrane
A9258_19210	ENOG4108UW5	maltose o-acetyltransferase
A9258_19235	ENOG4105CH7	arginosuccinase
A9258_19240	ENOG4105CDH	Citrulline--aspartate ligase
A9258_19250	ENOG4105CAS	nag kinase
A9258_19255	ENOG4105C0N	N-acetylglutamate semialdehyde dehydrogenase
A9258_19265	ENOG4105CCA	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle (By similarity)
A9258_19275	ENOG4105CFH	Aspartokinase
A9258_19280	ENOG4105C28	cystathionine
A9258_19285	ENOG4105GGQ	This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis (By similarity)
A9258_19290	ENOG41086D8	Transcriptional regulator
A9258_19295	ENOG4108Z7R	Chaperone CsaA
A9258_19300	ENOG4105C44	Serine transporter
A9258_19305	ENOG4108RNI	3'(2')5'-bisphosphate nucleotidase
A9258_19310	ENOG4107RK2	ADP-ribose diphosphatase NudE
A9258_19315	ENOG4107Y3D	HAD-superfamily hydrolase subfamily IA variant 3
A9258_19320	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
A9258_19325	ENOG4108UDW	Transcriptional regulator, luxr family
A9258_19365	ENOG4108VAU	general secretion pathway protein G
A9258_19370	ENOG4105D7Q	type ii secretion system
A9258_19375	ENOG4107QHF	type ii secretion system protein e
A9258_19380	ENOG4105GVR	general secretion pathway protein D
A9258_19390	ENOG4105VEJ	Heat shock protein
A9258_19395	ENOG4105F4C	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress (By similarity)
A9258_19400	ENOG4105DJ1	Phosphoenolpyruvate Carboxylase
A9258_19415	ENOG4105VXR	cytoplasmic protein
A9258_19420	ENOG4108R6G	acetyltransferase
A9258_19425	ENOG4108XTF	Outer Membrane Lipoprotein
A9258_19430	ENOG4107RNS	bifunctional 2',3'-cyclic nucleotide 2'-phosphodiesterase 3'-nucleotidase periplasmic
A9258_19435	ENOG4108ZUB	Lysine exporter protein (Lyse ygga)
A9258_19440	ENOG4105VJY	transcriptional regulator
A9258_19445	ENOG4105NNS	Autoinducer synthesis protein
A9258_19450	ENOG4105CXD	Specific inhibitor of chromosomal initiation of replication in vitro. Binds the three 13-mers in the origin (oriC) to block initiation of replication (By similarity)
A9258_19455	ENOG4108IEC	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction (By similarity)
A9258_19470	ENOG4105CTS	PTS system mannitol-specific
A9258_19475	ENOG4107SQ3	mannitol-1-phosphate 5-dehydrogenase
A9258_19480	ENOG4105E61	Mannitol repressor protein
A9258_19485	ENOG4105C3N	Participates in control of cell volume in low-osmolarity conditions (By similarity)
A9258_19510	ENOG4108UPT	UPF0178 protein
A9258_19525	ENOG4107K5X	Membrane-bound metal-dependent hydrolase
A9258_19530	ENOG4105D9N	nucleoside
A9258_19535	ENOG4105C1J	atp-dependent rna helicase
A9258_19560	ENOG4105EIS	1,4-dihydroxy-2-naphthoate octaprenyltransferase
A9258_19565	ENOG4105E4F	Isochorismate synthase
A9258_19570	ENOG4105C4A	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC) (By similarity)
A9258_19575	ENOG4107J5P	Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC). Is also able to catalyze the hydrolysis of the thioester bond in palmitoyl-CoA in vitro (By similarity)
A9258_19580	ENOG4108IPT	Naphthoate synthase
A9258_19585	ENOG4105DNI	Converts SHCHC to OSB (By similarity)
A9258_19590	ENOG4105CEY	Amp-dependent synthetase and ligase
A9258_19605	ENOG4108MDY	Fimbrial
A9258_19610	ENOG4108FZ9	Chaperone
A9258_19615	ENOG4106PG1	outer membrane usher protein
A9258_19625	ENOG4105HMV	Fimbrial protein
A9258_19635	ENOG4107MM9	BNR Asp-box repeat-containing protein
A9258_19640	ENOG4108UB4	uncharacterized protein ygjQ
A9258_19645	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
A9258_19655	ENOG4107IFA	Lipase (EC 3.1.1.3)
A9258_19675	ENOG4105KNR	Activates the small RNA gene sgrS under glucose- phosphate stress conditions as well as yfdZ. Represses its own transcription under both stress and non-stress conditions. Might act as a sensor of the intracellular accumulation of phosphoglucose by binding these molecules in its C-terminal solute-binding domain (By similarity)
A9258_19680	ENOG4108IQK	o-acetylhomoserine
A9258_19690	ENOG4108I6A	alcohol dehydrogenase
A9258_19705	ENOG4105DZW	Dipeptidase
A9258_19710	ENOG4105EMU	Dehydrogenase
A9258_19730	ENOG4105KT7	mgtC SapB transporter
A9258_19750	ENOG4105E0M	Sulfatase
A9258_19755	ENOG4108YXU	transcriptional regulator AsnC family
A9258_19765	ENOG4105CVG	Homoserine O-transsuccinylase
A9258_19770	ENOG4105E4Y	Endoribonuclease that initiates mRNA decay (By similarity)
A9258_19775	ENOG4108I62	cina-like protein
A9258_19785	ENOG4105CJ1	ABC, transporter
A9258_19800	ENOG410667J	hydrolase
A9258_19805	ENOG4108Z86	Glutamine amidotransferase
A9258_19815	ENOG4107RYR	Transcriptional regulator, Crp Fnr family
A9258_19825	ENOG4105DFC	had-superfamily hydrolase, subfamily ia, variant
A9258_19830	ENOG4108IYS	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
A9258_19840	ENOG4105E4Z	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan (By similarity)
A9258_19845	ENOG4105CU5	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity)
A9258_19850	ENOG4105XQ6	frataxin-like protein
A9258_19855	ENOG4106CJB	Phospholipase Carboxylesterase
A9258_19860	ENOG4107T0K	Adenylate cyclase
A9258_19865	ENOG4105D6W	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity)
A9258_19870	ENOG41076E6	Uroporphyrinogen-III Synthase
A9258_19875	ENOG4105ECF	c-methyltransferase
A9258_19890	ENOG4105CBT	Fructose-1,6-bisphosphatase
A9258_19905	ENOG4105E0K	tonB-dependent siderophore receptor
A9258_19930	ENOG4105KVH	Transcriptional regulator
A9258_19935	ENOG4105N0V	mono-oxygenase ydhR
A9258_19950	ENOG4108TPP	exopolysaccharide synthesis
A9258_19955	ENOG4105C44	Serine transporter
A9258_19960	ENOG4105BZU	Histidine kinase
A9258_19975	ENOG4108WEF	Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1B (PBP1b) (By similarity)
A9258_19985	ENOG4105D41	biosynthesis protein thiH
A9258_19990	ENOG4105CA8	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity)
A9258_20000	ENOG4105D06	uba thif-type nad fad binding protein
A9258_20005	ENOG4108UV6	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity)
A9258_20010	ENOG4105CBF	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction (By similarity)
A9258_20015	ENOG4107Y8H	Aerolysin toxin
A9258_20030	ENOG4105ETX	regulatoR
A9258_20040	ENOG4105CWM	branched-chain amino acid transport system II carrier protein
A9258_20045	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
A9258_20050	ENOG4105C3R	Methionine synthase
A9258_20055	ENOG4105EEQ	Na H antiporter
A9258_20080	ENOG41090ED	Protein with unknown function (DUF469)
A9258_20090	ENOG4105UYK	outer membrane protein a
A9258_20095	ENOG4106PG1	outer membrane usher protein
A9258_20100	ENOG4106P2F	Pfam:Pili_assembly_C
A9258_20145	ENOG4108HU6	Metal dependent phosphohydrolase
A9258_20155	ENOG4105CGZ	zinc metallopeptidase
A9258_20160	ENOG4105F0S	class B acid phosphatase
A9258_20175	ENOG4107SDU	Methyl-accepting chemotaxis
A9258_20180	ENOG4107MMM	Anti-sigma-factor antagonist
A9258_20185	ENOG4105QD0	anti-sigma regulatory factor serine threonine protein kinase
A9258_20190	ENOG4105BZU	Histidine kinase
A9258_20195	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
A9258_20205	ENOG4105CSH	Transporter
A9258_20220	ENOG4105E15	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
A9258_20225	ENOG4105C5Y	PTS System
A9258_20240	ENOG4108PSC	Represses the expression of the murPQ operon involved in the uptake and degradation of N-acetylmuramic acid (MurNAc). Binds to two adjacent inverted repeats within the operator region. MurNAc 6-phosphate, the substrate of MurQ, is the specific inducer that weakens binding of MurR to the operator (By similarity)
A9258_20245	ENOG4105D1U	peptidase U62 modulator of DNA gyrase
A9258_20260	ENOG4105QD6	exported protein
A9258_20265	ENOG4105C03	ribonuclease
A9258_20270	ENOG4108Z03	MAF-like protein
A9258_20275	ENOG4105VQ7	Rod shape-determining protein MreD
A9258_20280	ENOG4105N3I	Involved in formation and maintenance of cell shape (By similarity)
A9258_20285	ENOG4105DFF	Rod shape-determining protein mreb
A9258_20310	ENOG4106855	Competence protein
A9258_20330	ENOG4105D7Q	type ii secretion system
A9258_20335	ENOG4107QHF	type ii secretion system protein e
A9258_20345	ENOG4108WTW	DNA transposition protein
A9258_20350	ENOG4105GVR	general secretion pathway protein D
A9258_20380	ENOG41062P1	Diguanylate cyclase phosphodiesterase
A9258_20385	ENOG4107XTP	(EAL) domain protein
A9258_20390	ENOG4105EWV	Sodium calcium exchanger membrane region
A9258_20395	ENOG4105C84	Histidine ammonia-lyase
A9258_20400	ENOG4105CGP	Urocanate hydratase
A9258_20405	ENOG41088SP	formiminoglutamate hydrolase
A9258_20410	ENOG4105CI2	imidazolone-5-propionate hydrolase
A9258_20415	ENOG4105CZE	histidine utilization repressor
A9258_20420	ENOG41077A9	carbonic anhydrase
A9258_20430	ENOG4105CRP	Part of the ABC transporter FtsEX involved in
A9258_20435	ENOG4105CAK	Cell division ATP-binding protein ftsE
A9258_20440	ENOG4105CCP	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
A9258_20445	ENOG4106H78	methyltransferase
A9258_20460	ENOG4105EJ2	Transcriptional regulator
A9258_20470	ENOG4107RZC	phospholipase d
A9258_20475	ENOG4105E4C	Lytic transglycosylase catalytic
A9258_20485	ENOG4105WKS	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity)
A9258_20495	ENOG41076UM	multiple antibiotic resistance (MarC)-related protein
A9258_20500	ENOG4105VVZ	metal-binding protein
A9258_20515	ENOG4105JQN	Transcriptional regulator
A9258_20530	ENOG4107FS9	Membrane
A9258_20545	ENOG4105CUG	Oligopeptidase b
A9258_20560	ENOG4105EMU	Dehydrogenase
A9258_20565	ENOG4108W5M	transcriptional regulator
A9258_20570	ENOG4108K2R	Glutathione-regulated potassium-efflux system ancillary protein
A9258_20615	ENOG4108ZT0	50S ribosomal protein l17
A9258_20620	ENOG4105CTF	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
A9258_20625	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
A9258_20630	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
A9258_20635	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
A9258_20640	ENOG4105CGG	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity)
A9258_20645	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
A9258_20650	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
A9258_20655	ENOG4105K4C	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity)
A9258_20660	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
A9258_20665	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
A9258_20670	ENOG4105VBI	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
A9258_20675	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
A9258_20680	ENOG4105KAR	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity)
A9258_20685	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
A9258_20690	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
A9258_20695	ENOG41083MP	50s ribosomal protein l29
A9258_20700	ENOG4108R70	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity)
A9258_20705	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
A9258_20710	ENOG4105KAP	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity)
A9258_20715	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
A9258_20720	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
A9258_20725	ENOG41080KG	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
A9258_20730	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
A9258_20735	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
A9258_20740	ENOG4108Z10	Involved in the binding of tRNA to the ribosomes (By similarity)
A9258_20750	ENOG4105E0F	Histidine kinase
A9258_20755	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
A9258_20760	ENOG4108RRZ	Transcription elongation factor GreB
A9258_20765	ENOG4105BZM	domain protein
A9258_20785	ENOG4105D3C	The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters (By similarity)
A9258_20790	ENOG4105MJ2	Competence protein
A9258_20795	ENOG4107RUK	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins (By similarity)
A9258_20800	ENOG4105CSF	NADPH-dependent glycerol-3-phosphate dehydrogenase
A9258_20805	ENOG4105IX2	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA (By similarity)
A9258_20810	ENOG4107YZP	Rhodanese domain protein
A9258_20815	ENOG4105CJI	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
A9258_20820	ENOG41063SB	peptidase
A9258_20830	ENOG4105DIQ	Transcriptional regulator
A9258_20835	ENOG4108UHU	Aldolase
A9258_20840	ENOG4105C01	Dihydroxy-acid dehydratase
A9258_20845	ENOG4108Z67	carbohydrate kinase, thermoresistant glucokinase family
A9258_20850	ENOG4105C6Z	Gluconate
A9258_20855	ENOG4105JIM	Phosphatidylserine synthase
A9258_20860	ENOG4105CB5	ATP-dependent DNA helicase recG
A9258_20870	ENOG4105SUU	thioesterase domain
A9258_20880	ENOG4108YYA	Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine (By similarity)
A9258_20885	ENOG4107S2Z	UPF0761 membrane protein
A9258_20895	ENOG4105C5F	glutamine synthetase
A9258_20905	ENOG4105CUX	Signal transduction histidine kinase
A9258_20910	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
A9258_20915	ENOG4105EKD	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism (By similarity)
A9258_20920	ENOG4105D4P	Coproporphyrinogen iii oxidase
A9258_20925	ENOG4105XCT	Protein of unknown function (DUF2489)
A9258_20930	ENOG4105ZR3	A GTPase-activating protein (GAP) that modifies Der EngA GTPase function. May play a role in ribosome biogenesis (By similarity)
A9258_20940	ENOG4106RE7	Cytochrome
A9258_20945	ENOG4105WHM	Necessary for normal cell division and for the maintenance of normal septation (By similarity)
A9258_20950	ENOG4105SG3	Protein of unknown function (DUF1488)
A9258_20955	ENOG4105E2X	shikimate dehydrogenase
A9258_20960	ENOG4105DBS	Key enzyme in heme biosynthesis. Catalyzes the oxidative decarboxylation of propionic acid side chains of rings A and B of coproporphyrinogen III (By similarity)
A9258_20965	ENOG4105EK0	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
A9258_20975	ENOG4108WI1	Dna topoisomerase
A9258_20980	ENOG4108RPN	Protein smg homolog
A9258_20985	ENOG4105C79	DNA protecting protein DprA
A9258_20995	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
A9258_21000	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
A9258_21005	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
A9258_21010	ENOG4105C1A	potassium transporter peripheral membrane
A9258_21015	ENOG4105D37	Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA (By similarity)
A9258_21020	ENOG4105CGY	Dna recombination protein
A9258_21040	ENOG4108TFM	Kinase, PfkB family
A9258_21045	ENOG4105DCF	alanine dehydrogenase
A9258_21050	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
A9258_21055	ENOG4105C26	Dehydrogenase
A9258_21065	ENOG4108JCI	Transcriptional regulator
A9258_21070	ENOG4105C26	Dehydrogenase
A9258_21080	ENOG4105FR1	rard protein
A9258_21085	ENOG4105ECQ	AraC Family Transcriptional Regulator
A9258_21095	ENOG4105C52	Atpase, p-type (Transporting), had superfamily, subfamily ic
A9258_21100	ENOG4105CUC	YeeE YedE family protein
A9258_21105	ENOG410829K	Lysine exporter protein (Lyse ygga)
A9258_21115	ENOG4108YH8	Covalently attaches a chromophore to Cys residue(s) of phycobiliproteins (By similarity)
A9258_21140	ENOG41061EV	selenium-binding protein YdfZ
A9258_21150	ENOG4105HEI	LysR family (Transcriptional regulator
A9258_21155	ENOG4108UK5	Transposase
A9258_21160	ENOG4105C4R	Atp-dependent dna helicase
A9258_21165	ENOG4105DIH	basic membrane
A9258_21170	ENOG4108JQ9	ABC transporter
A9258_21175	ENOG4105UIB	(ABC) transporter
A9258_21185	ENOG4105CC0	LysR family Transcriptional regulator
A9258_21205	ENOG4105E46	N-alpha,N-alpha,N-alpha-trimethyl-L-histidine metabolic process
A9258_21210	ENOG4105DHU	Bile acid
A9258_21215	ENOG4105E5D	amino acid
A9258_21220	ENOG4108Y51	tRNA-binding protein
A9258_21225	ENOG4105E5D	amino acid
A9258_21230	ENOG4105FK9	beta-D-galactosidase beta subunit
A9258_21235	ENOG4105CNT	hydrolase family 2
A9258_21240	ENOG4105CQ4	Transcriptional regulator
A9258_21275	ENOG4108Z0R	Transferase
A9258_21280	ENOG4105C2M	dna polymerase I
A9258_21285	ENOG4108556	Isoprenoid biosynthesis protein with amidotransferase-like domain
A9258_21290	ENOG41065UX	Non-essential, abundant cell division factor that is required for proper Z-ring formation. It is recruited early to the divisome by direct interaction with FtsZ, stimulating Z-ring assembly and thereby promoting cell division earlier in the cell cycle. Its recruitment to the Z-ring requires functional FtsA or ZipA (By similarity)
A9258_21300	ENOG4105D7W	serine acetyltransferase
A9258_21310	ENOG4105E3W	Two component transcriptional regulator (Winged helix family
A9258_21315	ENOG4105E0F	Histidine kinase
A9258_21320	ENOG4108UIQ	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity)
A9258_21325	ENOG4107R73	Mate efflux family protein
A9258_21340	ENOG4105DS7	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity)
A9258_21345	ENOG4105E55	glycerol-3-phosphate acyltransferase
A9258_21350	ENOG4105C4G	Synthesis of 3-octaprenyl-4-hydroxybenzoate (By similarity)
A9258_21355	ENOG4105VEI	Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4- hydroxybenzoate (4HB) for the ubiquinone pathway (By similarity)
A9258_21360	ENOG4105X6C	Flagellar basal body-associated protein FliL
A9258_21370	ENOG4105D3Z	quinone oxidoreductase, yhdh yhfp family
A9258_21375	ENOG4105DIQ	Transcriptional regulator
A9258_21395	ENOG4105D8A	3-Deoxy-D-manno-octulosonic-acid transferase
A9258_21400	ENOG4105XA0	heptosyltransferase ii
A9258_21405	ENOG4106WTF	Glycosyl transferase, family 2
A9258_21410	ENOG4105M5K	heptosyltransferase
A9258_21415	ENOG4108ZEF	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity)
A9258_21420	ENOG4108MJ5	VirK protein
A9258_21425	ENOG4105ERD	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity)
A9258_21435	ENOG4105W0E	50S ribosomal protein L33
A9258_21440	ENOG4105W5Q	DNA repair protein (RadC
A9258_21445	ENOG4105CJS	Phosphopantothenoylcysteine decarboxylase
A9258_21450	ENOG4108Z1K	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA (By similarity)
A9258_21455	ENOG4105EC0	Required for nucleoid occlusion (NO) phenomenon, which prevents Z-ring formation and cell division over the nucleoid. Acts as a DNA-associated cell division inhibitor that binds simultaneously chromosomal DNA and FtsZ, and disrupts the assembly of FtsZ polymers. SlmA-DNA-binding sequences (SBS) are dispersed on non-Ter regions of the chromosome, preventing FtsZ polymerization at these regions (By similarity)
A9258_21460	ENOG4105D64	Mechanosensitive ion channel
A9258_21470	ENOG4107QP8	phosphohexose isomerase
A9258_21475	ENOG4105C6M	Alpha-keto-beta-hydroxylacyl reductoisomerase
A9258_21480	ENOG4105EMY	transcriptional regulator
A9258_21495	ENOG4105CD5	CoA-binding domain protein
A9258_21520	ENOG4108RR8	protoporphyrinogen oxidase
A9258_21525	ENOG4105D37	Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA (By similarity)
A9258_21530	ENOG4108ZK7	protein family UPF0029, Impact, N-terminal protein
A9258_21535	ENOG4105D9Y	Splits dipeptides with a prolyl residue in the C- terminal position (By similarity)
A9258_21540	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
A9258_21545	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
A9258_21550	ENOG4105CHU	acetyl-coa acetyltransferase
A9258_21555	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
A9258_21560	ENOG4105E0F	Histidine kinase
A9258_21575	ENOG41082K8	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Interacts with IscS and stimulates its activity. Then, accepts a sulfur from IscS and transfers it in turn to TusD (By similarity)
A9258_21580	ENOG4105M4H	endoribonuclease L-psp
A9258_21585	ENOG4108ZG0	Ompa motb domain protein
A9258_21590	ENOG4105D3W	isochorismatase
A9258_21595	ENOG4108R3E	Dna-3-methyladenine glycosylase i
A9258_21600	ENOG4108HMW	glycyl-tRNA synthetase, alpha subunit
A9258_21605	ENOG4105C38	Glycyl-tRNA synthetase beta subunit
A9258_21620	ENOG4107RIQ	Sulfate adenylate transferase
A9258_21640	ENOG4105CIC	tryptophan-specific transport protein
A9258_21645	ENOG4105HEE	Binding Domain protein
A9258_21655	ENOG4108EQM	faD-dependent pyridine nucleotide-disulfide oxidoreductase
A9258_21660	ENOG4105CNW	domain protein
A9258_21665	ENOG4108JUA	Transcriptional regulator
A9258_21670	ENOG4105FDP	GntR family transcriptional regulator
A9258_21675	ENOG4105CI1	PTS System
A9258_21680	ENOG4105F8D	glycoside hydrolase family 4
A9258_21685	ENOG4105ETE	Transcriptional regulator (LacI family
A9258_21690	ENOG4105CP9	extracellular ligand-binding receptor
A9258_21695	ENOG4105C32	Amino acid ABC transporter (Permease)
A9258_21700	ENOG4105CF8	branched-chain amino acid ABC transporter, permease
A9258_21705	ENOG4105C0Z	ABC transporter
A9258_21710	ENOG4108IV0	ABC, transporter
A9258_21725	ENOG4105M78	Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide (By similarity)
A9258_21740	ENOG4105W0Z	cytoplasmic protein
A9258_21745	ENOG4107QK7	reductase
A9258_21750	ENOG4105D3H	Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol (By similarity)
A9258_21760	ENOG4105C4P	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity)
A9258_21765	ENOG4105K63	Thioredoxin
A9258_21770	ENOG4105C1J	atp-dependent rna helicase
A9258_21775	ENOG4105C9X	ppx gppa phosphatase
A9258_21790	ENOG4105FFN	Specifically methylates the guanosine in position 1516 of 16S rRNA (By similarity)
A9258_21795	ENOG4105BZU	Histidine kinase
A9258_21800	ENOG4105DGW	oligopeptidase A
A9258_21805	ENOG4105D52	delta-aminolevulinic acid dehydratase
A9258_21810	ENOG4105F8V	Hydrolase, tatD family
A9258_21815	ENOG4105DCX	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity)
A9258_21820	ENOG4105X8U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation (By similarity)
A9258_21825	ENOG4105WKS	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity)
A9258_21830	ENOG4105CNK	Required, probably indirectly, for the hydroxylation of 2-octaprenylphenol to 2-octaprenyl-6-hydroxy-phenol, the fourth step in ubiquinone biosynthesis (By similarity)
A9258_21835	ENOG4105JC1	sterol-binding domain protein
A9258_21845	ENOG4105WMR	Protein CrcB homolog
A9258_21850	ENOG4105DZC	cytosine deaminase
A9258_21890	ENOG410822N	TonB family
A9258_21895	ENOG4109015	Biopolymer transport protein exbD tolR
A9258_21915	ENOG4105VJY	transcriptional regulator
A9258_21920	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
A9258_21925	ENOG410804X	Transcriptional regulator
A9258_21930	ENOG4105E3W	Two component transcriptional regulator (Winged helix family
A9258_21935	ENOG4105EB3	Histidine kinase
A9258_21945	ENOG4105CT7	inner membrane cred family protein
A9258_21950	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
A9258_21955	ENOG4105KNM	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
A9258_21960	ENOG4105C4J	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity)
A9258_21965	ENOG4105J80	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity)
A9258_21970	ENOG4105CDG	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity)
A9258_21975	ENOG4107S15	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
A9258_21980	ENOG4107Z6K	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
A9258_21985	ENOG4105KY6	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
A9258_21990	ENOG4105EE4	it plays a direct role in the translocation of protons across the membrane (By similarity)
A9258_22000	ENOG4105FA0	parb-like partition protein
A9258_22005	ENOG4107QJE	Chromosome Partitioning Protein
A9258_22010	ENOG4105D28	Specifically methylates the N7 position of a guanine in 16S rRNA (By similarity)
A9258_22015	ENOG4107RE5	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity)
A9258_22020	ENOG4105QTB	Flavodoxin
A9258_22025	ENOG4105E0K	tonB-dependent siderophore receptor
A9258_22030	ENOG4105IBP	Cyclic peptide transporter
A9258_22035	ENOG4105E0A	ABC, transporter
A9258_22045	ENOG4105S6R	Iron-hydroxamate transporter permease subunit
A9258_22050	ENOG4105C1H	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity)
A9258_22055	ENOG4105DHW	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
A9258_22060	ENOG4105NVJ	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme (By similarity)
A9258_22065	ENOG4105CDA	abc transporter atp-binding protein
A9258_22070	ENOG4105E5Q	amino acid AbC transporter
A9258_22075	ENOG4105EAB	amino acid AbC transporter