locus-tag	class	description
GQR50_00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
GQR50_00010	COG0592	DNA-directed DNA polymerase activity
GQR50_00015	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
GQR50_00020	COG0187	DNA topoisomerase II activity
GQR50_00030	COG2378	regulation of single-species biofilm formation
GQR50_00035	COG0071	Belongs to the small heat shock protein (HSP20) family
GQR50_00040	COG0071	Belongs to the small heat shock protein (HSP20) family
GQR50_00045	COG3977	Valine--pyruvate aminotransferase
GQR50_00060	COG2814	Major facilitator Superfamily
GQR50_00065	COG0745	RESPONSE REGULATOR receiver
GQR50_00070	COG2205	protein histidine kinase activity
GQR50_00095	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
GQR50_00100	COG4191	Histidine kinase
GQR50_00100	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GQR50_00105	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
GQR50_00110	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GQR50_00115	COG1309	transcriptional regulator
GQR50_00145	COG0561	phosphatase activity
GQR50_00150	COG2267	carboxylic ester hydrolase activity
GQR50_00155	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
GQR50_00160	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
GQR50_00165	COG1758	RNA polymerase activity
GQR50_00175	COG0859	PFAM glycosyl transferase family 9
GQR50_00180	COG3642	lipopolysaccharide core region biosynthetic process
GQR50_00220	COG0589	response to stress
GQR50_00225	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
GQR50_00230	COG3706	GGDEF domain
GQR50_00235	COG1528	Iron-storage protein
GQR50_00240	COG2081	HI0933 family
GQR50_00245	COG2223	nitrite transmembrane transporter activity
GQR50_00250	COG1280	lysine exporter protein (LysE YggA)
GQR50_00295	COG2197	response regulator
GQR50_00300	COG2205	protein histidine kinase activity
GQR50_00300	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GQR50_00310	COG3275	phosphorelay sensor kinase activity
GQR50_00315	COG3279	Response regulator of the LytR AlgR family
GQR50_00320	COG2223	nitrite transmembrane transporter activity
GQR50_00325	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
GQR50_00330	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
GQR50_00345	COG0583	DNA-binding transcription factor activity
GQR50_00350	COG4206	TonB-dependent receptor
GQR50_00355	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
GQR50_00395	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
GQR50_00400	COG2166	iron-sulfur cluster assembly
GQR50_00405	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
GQR50_00410	COG0210	DNA helicase
GQR50_00420	COG3245	cytochrome
GQR50_00425	COG1063	alcohol dehydrogenase
GQR50_00430	COG0156	8-amino-7-oxononanoate synthase activity
GQR50_00440	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GQR50_00450	COG3307	-O-antigen
GQR50_00455	COG0463	Glycosyl transferase, family 2
GQR50_00465	COG1561	YicC-like family, N-terminal region
GQR50_00470	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
GQR50_00475	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
GQR50_00485	COG0789	Transcriptional regulator
GQR50_00490	COG4251	negative regulation of phosphorylation
GQR50_00490	COG5001	Diguanylate cyclase
GQR50_00490	COG2203	Gaf domain
GQR50_00490	COG3706	GGDEF domain
GQR50_00495	COG3084	Protein conserved in bacteria
GQR50_00505	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
GQR50_00510	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
GQR50_00515	COG3639	organic phosphonate transmembrane transporter activity
GQR50_00520	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
GQR50_00525	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
GQR50_00535	COG1335	isochorismatase
GQR50_00545	COG1683	Conserved Protein
GQR50_00550	COG0204	Acyl-transferase
GQR50_00555	COG0204	Acyl-transferase
GQR50_00560	COG0606	chelatase, subunit chli
GQR50_00575	COG3978	acetolactate synthase activity
GQR50_00580	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
GQR50_00585	COG0129	dihydroxy-acid dehydratase activity
GQR50_00615	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
GQR50_00620	COG0254	rRNA binding
GQR50_00625	COG0702	epimerase
GQR50_00630	COG0281	malic enzyme
GQR50_00640	COG2205	protein histidine kinase activity
GQR50_00645	COG0745	RESPONSE REGULATOR receiver
GQR50_00650	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
GQR50_00670	COG0366	Alpha amylase catalytic
GQR50_00680	COG3187	Heat shock protein
GQR50_00685	COG0443	Heat shock 70 kDa protein
GQR50_00690	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
GQR50_00695	COG3045	CreA protein
GQR50_00710	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
GQR50_00715	COG0174	glutamine synthetase
GQR50_00735	COG3842	ATPase activity
GQR50_00740	COG1176	ABC-type spermidine putrescine transport system, permease component I
GQR50_00745	COG1177	transmembrane transport
GQR50_00750	COG2258	MOSC domain
GQR50_00765	COG2050	protein possibly involved in aromatic compounds catabolism
GQR50_00770	COG0514	ATP-dependent DNA helicase (RecQ)
GQR50_00780	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
GQR50_00790	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
GQR50_00795	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
GQR50_00805	COG2239	Acts as a magnesium transporter
GQR50_00810	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
GQR50_00810	COG1648	precorrin-2 dehydrogenase activity
GQR50_00815	COG2116	formate transmembrane transporter activity
GQR50_00820	COG2146	nitrite reductase [NAD(P)H] activity
GQR50_00825	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
GQR50_00840	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
GQR50_00845	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
GQR50_00865	COG1595	DNA-templated transcription, initiation
GQR50_00870	COG3806	Anti-sigma factor
GQR50_00875	COG1968	undecaprenyl-diphosphatase activity
GQR50_00880	COG0667	Aldo Keto reductase
GQR50_00885	COG2017	converts alpha-aldose to the beta-anomer
GQR50_00890	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
GQR50_00900	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
GQR50_00905	COG1609	Transcriptional regulator
GQR50_00910	COG3250	beta-galactosidase activity
GQR50_00930	COG0840	transmembrane signaling receptor activity
GQR50_00960	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
GQR50_00965	COG1288	antiporter activity
GQR50_00970	COG1438	arginine binding
GQR50_00975	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
GQR50_00980	COG0540	Belongs to the ATCase OTCase family
GQR50_01015	COG0583	DNA-binding transcription factor activity
GQR50_01030	COG2207	Transcriptional regulator
GQR50_01035	COG1979	alcohol dehydrogenase
GQR50_01040	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
GQR50_01045	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
GQR50_01055	COG3681	Belongs to the UPF0597 family
GQR50_01065	COG0446	pyridine nucleotide-disulphide oxidoreductase
GQR50_01070	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
GQR50_01075	COG0564	pseudouridine synthase activity
GQR50_01085	COG0542	response to heat
GQR50_01090	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
GQR50_01100	COG2502	aspartate--ammonia ligase
GQR50_01105	COG1522	sequence-specific DNA binding
GQR50_01115	COG5413	integral membrane protein
GQR50_01140	COG2205	protein histidine kinase activity
GQR50_01150	COG2204	response regulator
GQR50_01185	COG0745	RESPONSE REGULATOR receiver
GQR50_01190	COG2205	protein histidine kinase activity
GQR50_01200	COG0243	molybdopterin cofactor binding
GQR50_01205	COG3005	denitrification pathway
GQR50_01210	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
GQR50_01230	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
GQR50_01235	COG0569	domain protein
GQR50_01240	COG0812	UDP-N-acetylmuramate dehydrogenase activity
GQR50_01265	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
GQR50_01275	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
GQR50_01280	COG0250	Participates in transcription elongation, termination and antitermination
GQR50_01285	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
GQR50_01290	COG0081	regulation of translation
GQR50_01295	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
GQR50_01300	COG0222	ribosome binding
GQR50_01305	COG0085	RNA polymerase activity
GQR50_01310	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
GQR50_01315	COG2964	Protein conserved in bacteria
GQR50_01320	COG0251	oxidation-reduction process
GQR50_01330	COG2923	Belongs to the DsrF TusC family
GQR50_01335	COG2168	tRNA wobble position uridine thiolation
GQR50_01340	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
GQR50_01345	COG0049	tRNA binding
GQR50_01350	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
GQR50_01355	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
GQR50_01360	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
GQR50_01395	COG2252	PERMEase
GQR50_01400	COG2376	Dihydroxyacetone kinase
GQR50_01405	COG1461	Dihydroxyacetone kinase
GQR50_01420	COG3284	Transcriptional regulator
GQR50_01425	COG0583	DNA-binding transcription factor activity
GQR50_01430	COG2957	Belongs to the agmatine deiminase family
GQR50_01435	COG4221	oxidoreductase activity
GQR50_01440	COG0628	permease
GQR50_01445	COG0494	nUDIX hydrolase
GQR50_01470	COG0753	catalase activity
GQR50_01475	COG1247	-acetyltransferase
GQR50_01495	COG3706	GGDEF domain
GQR50_01505	COG3842	ATPase activity
GQR50_01515	COG1176	ABC-type spermidine putrescine transport system, permease component I
GQR50_01540	COG0583	DNA-binding transcription factor activity
GQR50_01550	COG1741	Belongs to the pirin family
GQR50_01555	COG2259	Doxx family
GQR50_01560	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
GQR50_01565	COG1074	ATP-dependent DNA helicase activity
GQR50_01570	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
GQR50_01580	COG3039	Transposase
GQR50_01595	COG0346	lactoylglutathione lyase activity
GQR50_01635	COG0745	RESPONSE REGULATOR receiver
GQR50_01645	COG3706	GGDEF domain
GQR50_01645	COG4251	negative regulation of phosphorylation
GQR50_01645	COG2203	Gaf domain
GQR50_01645	COG5001	Diguanylate cyclase
GQR50_01650	COG4771	TonB-dependent receptor
GQR50_01655	COG1278	Cold shock
GQR50_01680	COG0629	single-stranded DNA binding
GQR50_01685	COG2197	response regulator
GQR50_01690	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
GQR50_01695	COG3706	GGDEF domain
GQR50_01730	COG3135	benzoate transporter
GQR50_01735	COG1396	sequence-specific DNA binding
GQR50_01765	COG2926	Belongs to the UPF0265 family
GQR50_01775	COG3028	Belongs to the UPF0307 family
GQR50_01780	COG0312	modulator of DNA gyrase
GQR50_01785	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
GQR50_01790	COG5007	Belongs to the BolA IbaG family
GQR50_01800	COG2854	intermembrane phospholipid transfer
GQR50_01805	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
GQR50_01810	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
GQR50_01815	COG1127	ABC transporter
GQR50_01820	COG0517	IMP dehydrogenase activity
GQR50_01820	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
GQR50_01825	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
GQR50_01830	COG3117	lipopolysaccharide transmembrane transporter activity
GQR50_01835	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
GQR50_01840	COG1137	ATPase activity
GQR50_01845	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
GQR50_01855	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
GQR50_01860	COG1660	Displays ATPase and GTPase activities
GQR50_01865	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
GQR50_01870	COG3711	transcriptional antiterminator
GQR50_01870	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
GQR50_01885	COG3964	amidohydrolase
GQR50_01915	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GQR50_01920	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GQR50_01930	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
GQR50_01935	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
GQR50_01940	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GQR50_01945	COG0723	plastoquinol--plastocyanin reductase activity
GQR50_01950	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
GQR50_01955	COG2857	Cytochrome c1
GQR50_01960	COG0625	glutathione transferase activity
GQR50_01965	COG2969	positive regulation of protein catabolic process
GQR50_01970	COG2823	Periplasmic or secreted lipoprotein
GQR50_01975	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
GQR50_01980	COG0792	nuclease activity
GQR50_01985	COG3107	peptidoglycan biosynthetic process
GQR50_01990	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
GQR50_02000	COG2001	Belongs to the MraZ family
GQR50_02005	COG0275	rRNA processing
GQR50_02010	COG3116	cell division
GQR50_02015	COG0768	penicillin binding
GQR50_02025	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
GQR50_02030	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
GQR50_02035	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
GQR50_02040	COG0772	Belongs to the SEDS family
GQR50_02045	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
GQR50_02050	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
GQR50_02055	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
GQR50_02060	COG0849	cell division
GQR50_02065	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
GQR50_02070	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
GQR50_02080	COG0653	protein targeting
GQR50_02090	COG0494	nUDIX hydrolase
GQR50_02095	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
GQR50_02100	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
GQR50_02115	COG1459	type II secretion system
GQR50_02120	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
GQR50_02145	COG2186	Transcriptional regulator
GQR50_02150	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
GQR50_02155	COG0508	dehydrogenase complex catalyzes the overall conversion of
GQR50_02160	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
GQR50_02165	COG5001	Diguanylate cyclase
GQR50_02165	COG5002	protein histidine kinase activity
GQR50_02165	COG3447	MASE1 domain protein
GQR50_02175	COG0840	transmembrane signaling receptor activity
GQR50_02180	COG0840	transmembrane signaling receptor activity
GQR50_02185	COG1752	Esterase of the alpha-beta hydrolase superfamily
GQR50_02190	COG1049	propionate catabolic process, 2-methylcitrate cycle
GQR50_02195	COG2200	EAL domain
GQR50_02205	COG1280	lysine exporter protein (LysE YggA)
GQR50_02215	COG0523	cobalamin synthesis protein
GQR50_02220	COG0477	Major facilitator Superfamily
GQR50_02235	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
GQR50_02240	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
GQR50_02285	COG0835	chemotaxis
GQR50_02285	COG0784	Response regulator, receiver
GQR50_02290	COG1028	Short-chain dehydrogenase reductase Sdr
GQR50_02295	COG1444	tRNA N-acetyltransferase activity
GQR50_02320	COG1803	Methylglyoxal synthase
GQR50_02335	COG0252	asparaginase activity
GQR50_02355	COG1263	PTS System
GQR50_02355	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GQR50_02360	COG0366	Alpha amylase catalytic
GQR50_02365	COG0110	maltose O-acetyltransferase activity
GQR50_02370	COG1522	sequence-specific DNA binding
GQR50_02375	COG5006	permease, DMT superfamily
GQR50_02385	COG1012	belongs to the aldehyde dehydrogenase family
GQR50_02390	COG1177	transmembrane transport
GQR50_02395	COG1176	ABC-type spermidine putrescine transport system, permease component I
GQR50_02400	COG3842	ATPase activity
GQR50_02405	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
GQR50_02410	COG0583	DNA-binding transcription factor activity
GQR50_02415	COG1757	Na H antiporter
GQR50_02455	COG0297	glycogen (starch) synthase activity
GQR50_02460	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
GQR50_02465	COG2813	Specifically methylates the guanine in position
GQR50_02470	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
GQR50_02475	COG2203	Gaf domain
GQR50_02475	COG5001	Diguanylate cyclase
GQR50_02475	COG4251	negative regulation of phosphorylation
GQR50_02475	COG3706	GGDEF domain
GQR50_02485	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
GQR50_02495	COG2995	paraquat-inducible protein a
GQR50_02500	COG3008	intermembrane lipid transfer
GQR50_02500	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
GQR50_02505	COG3009	Protein conserved in bacteria
GQR50_02510	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
GQR50_02510	COG2885	chlorophyll binding
GQR50_02520	COG3240	lipase activity
GQR50_02525	COG3111	PFAM Bacterial OB fold (BOF) protein
GQR50_02535	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
GQR50_02540	COG1194	a g-specific adenine glycosylase
GQR50_02550	COG3267	Type II secretory pathway component ExeA
GQR50_02550	COG3409	Peptidoglycan-binding domain 1 protein
GQR50_02555	COG0617	tRNA 3'-terminal CCA addition
GQR50_02570	COG1346	cytolysis
GQR50_02575	COG1380	Effector of murein hydrolase LrgA
GQR50_02580	COG0583	DNA-binding transcription factor activity
GQR50_02610	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
GQR50_02615	COG0306	phosphate transporter
GQR50_02620	COG1392	Phosphate transport regulator
GQR50_02635	COG1560	Kdo2-lipid A biosynthetic process
GQR50_02640	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
GQR50_02640	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
GQR50_02645	COG1538	Outer membrane efflux protein
GQR50_02650	COG0494	nUDIX hydrolase
GQR50_02655	COG3151	Protein conserved in bacteria
GQR50_02665	COG3150	esterase
GQR50_02670	COG1051	belongs to the nudix hydrolase family
GQR50_02685	COG1566	PFAM secretion protein HlyD family protein
GQR50_02690	COG1289	transmembrane transporter activity
GQR50_02695	COG0187	DNA topoisomerase II activity
GQR50_02710	COG0583	DNA-binding transcription factor activity
GQR50_02750	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GQR50_02775	COG0204	Acyl-transferase
GQR50_02780	COG1842	Phage shock protein A
GQR50_02795	COG2827	Endonuclease containing a URI domain
GQR50_02805	COG2962	Rard protein
GQR50_02810	COG1573	uracil-dna glycosylase
GQR50_02815	COG0697	spore germination
GQR50_02820	COG0583	DNA-binding transcription factor activity
GQR50_02825	COG1108	ABC-type Mn2 Zn2 transport systems permease components
GQR50_02830	COG1121	(ABC) transporter
GQR50_02835	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
GQR50_02855	COG0739	heme binding
GQR50_02860	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
GQR50_02865	COG3068	Protein conserved in bacteria
GQR50_02885	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
GQR50_02910	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
GQR50_02925	COG0732	type I restriction modification DNA specificity domain
GQR50_02950	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
GQR50_02970	COG1546	Belongs to the CinA family
GQR50_02975	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
GQR50_02985	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
GQR50_02990	COG0527	aspartate kinase activity
GQR50_02995	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
GQR50_03030	COG1686	Belongs to the peptidase S11 family
GQR50_03035	COG0586	Pfam SNARE associated Golgi protein
GQR50_03040	COG1253	flavin adenine dinucleotide binding
GQR50_03045	COG0525	valine-tRNA ligase activity
GQR50_03050	COG2927	DNA polymerase III (CHI subunit)
GQR50_03055	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
GQR50_03060	COG0795	lipopolysaccharide-transporting ATPase activity
GQR50_03065	COG0795	lipopolysaccharide-transporting ATPase activity
GQR50_03080	COG0004	ammonium transporteR
GQR50_03085	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
GQR50_03095	COG0084	hydrolase, TatD family'
GQR50_03100	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
GQR50_03110	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
GQR50_03115	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
GQR50_03120	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
GQR50_03125	COG0813	purine-nucleoside phosphorylase activity
GQR50_03130	COG5001	Diguanylate cyclase
GQR50_03130	COG5002	protein histidine kinase activity
GQR50_03130	COG3447	MASE1 domain protein
GQR50_03140	COG0560	Phosphoserine phosphatase
GQR50_03165	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
GQR50_03175	COG0776	regulation of translation
GQR50_03190	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
GQR50_03195	COG0735	belongs to the Fur family
GQR50_03220	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
GQR50_03225	COG0513	Belongs to the DEAD box helicase family
GQR50_03230	COG3022	response to hydroperoxide
GQR50_03245	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
GQR50_03250	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
GQR50_03255	COG0762	integral membrane protein
GQR50_03260	COG1872	DUF167
GQR50_03275	COG4166	transmembrane transport
GQR50_03295	COG1024	Enoyl-CoA hydratase
GQR50_03310	COG4221	oxidoreductase activity
GQR50_03315	COG0442	prolyl-tRNA aminoacylation
GQR50_03320	COG0840	transmembrane signaling receptor activity
GQR50_03325	COG0632	four-way junction helicase activity
GQR50_03330	COG2255	four-way junction helicase activity
GQR50_03335	COG1271	oxidase subunit
GQR50_03340	COG1294	oxidase, subunit
GQR50_03345	COG4890	Cyd operon protein YbgT
GQR50_03350	COG3790	cyd operon protein YbgE
GQR50_03355	COG0824	Thioesterase
GQR50_03360	COG0811	peptide transport
GQR50_03375	COG0823	Involved in the tonB-independent uptake of proteins
GQR50_03380	COG2885	chlorophyll binding
GQR50_03385	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
GQR50_03460	COG0840	transmembrane signaling receptor activity
GQR50_03465	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
GQR50_03470	COG0676	glucose-6-phosphate 1-epimerase activity
GQR50_03475	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
GQR50_03480	COG1640	4-alpha-glucanotransferase
GQR50_03485	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
GQR50_03505	COG1051	belongs to the nudix hydrolase family
GQR50_03510	COG2130	NADP-dependent
GQR50_03515	COG1764	response to oxidative stress
GQR50_03520	COG1846	Transcriptional regulator
GQR50_03535	COG1522	sequence-specific DNA binding
GQR50_03555	COG0561	phosphatase activity
GQR50_03570	COG0733	neurotransmitter:sodium symporter activity
GQR50_03580	COG0733	neurotransmitter:sodium symporter activity
GQR50_03605	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GQR50_03615	COG1794	racemase activity, acting on amino acids and derivatives
GQR50_03630	COG2731	YhcH YjgK YiaL family protein
GQR50_03640	COG0668	transmembrane transport
GQR50_03650	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GQR50_03680	COG0583	DNA-binding transcription factor activity
GQR50_03685	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
GQR50_03695	COG0488	(ABC) transporter
GQR50_03700	COG0517	IMP dehydrogenase activity
GQR50_03700	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
GQR50_03705	COG1585	Membrane protein implicated in regulation of membrane protease activity
GQR50_03710	COG0330	HflC and HflK could
GQR50_03715	COG1648	precorrin-2 dehydrogenase activity
GQR50_03715	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
GQR50_03720	COG0175	sulfate reduction
GQR50_03725	COG2895	sulfate adenylyltransferase (ATP) activity
GQR50_03730	COG3273	potassium ion transport
GQR50_03730	COG0471	metal ion transport
GQR50_03735	COG0529	Catalyzes the synthesis of activated sulfate
GQR50_03770	COG0625	glutathione transferase activity
GQR50_03805	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
GQR50_03825	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
GQR50_03830	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
GQR50_03835	COG0163	prenyltransferase activity
GQR50_03850	COG1131	(ABC) transporter
GQR50_03855	COG0842	Transport permease protein
GQR50_03860	COG1775	2-hydroxyglutaryl-CoA dehydratase, D-component
GQR50_03865	COG1924	4 iron, 4 sulfur cluster binding
GQR50_03885	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
GQR50_03890	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
GQR50_03905	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
GQR50_03910	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
GQR50_03915	COG1489	DNA binding
GQR50_03925	COG1643	Atp-dependent helicase
GQR50_03930	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
GQR50_03935	COG0346	lactoylglutathione lyase activity
GQR50_03945	COG2076	Multidrug Resistance protein
GQR50_03955	COG3437	response regulator, receiver
GQR50_03955	COG0784	Response regulator, receiver
GQR50_03965	COG0671	phosphoesterase, PA-phosphatase related
GQR50_03980	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
GQR50_03985	COG0038	chloride channel
GQR50_03995	COG0316	Belongs to the HesB IscA family
GQR50_04020	COG1280	lysine exporter protein (LysE YggA)
GQR50_04040	COG2916	Histone family protein nucleoid-structuring protein H-NS
GQR50_04050	COG3311	Transcriptional regulator
GQR50_04100	COG2003	Belongs to the UPF0758 family
GQR50_04185	COG3293	Transposase
GQR50_04200	COG4584	PFAM Integrase catalytic
GQR50_04205	COG1484	DNA-dependent DNA replication
GQR50_04240	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
GQR50_04255	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GQR50_04285	COG0745	RESPONSE REGULATOR receiver
GQR50_04290	COG3104	oligopeptide transport
GQR50_04295	COG1210	Utp--glucose-1-phosphate uridylyltransferase
GQR50_04300	COG1555	photosystem II stabilization
GQR50_04310	COG2350	Protein conserved in bacteria
GQR50_04315	COG2917	probably involved in intracellular septation
GQR50_04320	COG0076	glutamate decarboxylase activity
GQR50_04325	COG1272	protein, Hemolysin III
GQR50_04330	COG2985	domain, Protein
GQR50_04330	COG0569	domain protein
GQR50_04395	COG0835	chemotaxis
GQR50_04395	COG0784	Response regulator, receiver
GQR50_04400	COG2755	lipolytic protein G-D-S-L family
GQR50_04405	COG4181	ATPase activity
GQR50_04410	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
GQR50_04415	COG1090	epimerase
GQR50_04420	COG2200	EAL domain
GQR50_04425	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GQR50_04430	COG4935	Belongs to the peptidase S8 family
GQR50_04430	COG2234	aminopeptidase activity
GQR50_04435	COG0220	tRNA (guanine-N7-)-methyltransferase activity
GQR50_04440	COG3171	Protein conserved in bacteria
GQR50_04445	COG2066	Belongs to the glutaminase family
GQR50_04450	COG2897	thiosulfate sulfurtransferase activity
GQR50_04455	COG1404	Belongs to the peptidase S8 family
GQR50_04465	COG1132	(ABC) transporter
GQR50_04490	COG4412	M6 family metalloprotease domain protein
GQR50_04490	COG3291	Pkd domain containing protein
GQR50_04495	COG3076	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome
GQR50_04500	COG5001	Diguanylate cyclase
GQR50_04500	COG3300	MHYT domain
GQR50_04515	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
GQR50_04520	COG3059	membrane
GQR50_04535	COG4628	conserved protein (DUF2132)
GQR50_04540	COG0688	phosphatidylethanolamine metabolic process
GQR50_04545	COG1162	GTPase activity
GQR50_04550	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
GQR50_04590	COG1278	Cold shock
GQR50_04600	COG0840	transmembrane signaling receptor activity
GQR50_04605	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
GQR50_04655	COG0848	biopolymer transport protein
GQR50_04660	COG0811	peptide transport
GQR50_04665	COG0811	peptide transport
GQR50_04680	COG4174	ABC transporter (Permease)
GQR50_04685	COG4239	(ABC) transporter, permease
GQR50_04695	COG0444	Belongs to the ABC transporter superfamily
GQR50_04700	COG4608	Belongs to the ABC transporter superfamily
GQR50_04710	COG2195	Cleaves the N-terminal amino acid of tripeptides
GQR50_04720	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
GQR50_04740	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
GQR50_04770	COG0243	molybdopterin cofactor binding
GQR50_04785	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
GQR50_04785	COG1116	anion transmembrane transporter activity
GQR50_04790	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
GQR50_04795	COG1116	anion transmembrane transporter activity
GQR50_04800	COG2146	nitrite reductase [NAD(P)H] activity
GQR50_04800	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
GQR50_04805	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
GQR50_04805	COG2146	nitrite reductase [NAD(P)H] activity
GQR50_04810	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GQR50_04815	COG2313	pseudouridylate synthase activity
GQR50_04825	COG1858	cytochrome C peroxidase
GQR50_04860	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
GQR50_04865	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
GQR50_04890	COG2986	histidine ammonia-lyase
GQR50_04915	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
GQR50_04925	COG1028	Short-chain dehydrogenase reductase Sdr
GQR50_04930	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
GQR50_04940	COG0521	Mo-molybdopterin cofactor biosynthetic process
GQR50_04950	COG2966	Psort location CytoplasmicMembrane, score
GQR50_04955	COG3610	response to peptide
GQR50_04965	COG4175	Glycine betaine
GQR50_04970	COG4176	ABC-type proline glycine betaine transport system permease component
GQR50_04975	COG2113	Glycine betaine
GQR50_04980	COG0175	sulfate reduction
GQR50_04985	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
GQR50_04990	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
GQR50_04995	COG0384	phenazine biosynthesis protein PhzF
GQR50_05000	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
GQR50_05015	COG0786	glutamate:sodium symporter activity
GQR50_05020	COG0252	asparaginase activity
GQR50_05030	COG2425	protein containing a von Willebrand factor type A (vWA) domain
GQR50_05035	COG3139	Protein of unknown function (DUF1315)
GQR50_05055	COG0616	signal peptide processing
GQR50_05060	COG1902	pentaerythritol trinitrate reductase activity
GQR50_05060	COG0446	pyridine nucleotide-disulphide oxidoreductase
GQR50_05065	COG0778	Nitroreductase
GQR50_05075	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
GQR50_05080	COG2264	protein methyltransferase activity
GQR50_05085	COG0604	alcohol dehydrogenase
GQR50_05090	COG0583	DNA-binding transcription factor activity
GQR50_05095	COG2190	(PTS) system
GQR50_05095	COG1263	PTS System
GQR50_05095	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GQR50_05100	COG4145	pantothenate transmembrane transporter activity
GQR50_05110	COG0439	Biotin carboxylase
GQR50_05115	COG0511	ligase activity, forming carbon-carbon bonds
GQR50_05120	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
GQR50_05125	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
GQR50_05155	COG3381	protein complex oligomerization
GQR50_05165	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
GQR50_05175	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
GQR50_05180	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
GQR50_05180	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
GQR50_05195	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
GQR50_05200	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
GQR50_05205	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
GQR50_05210	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
GQR50_05235	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
GQR50_05240	COG0142	geranyltranstransferase activity
GQR50_05245	COG1722	exodeoxyribonuclease VII activity
GQR50_05250	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
GQR50_05255	COG1360	Flagellar Motor Protein
GQR50_05260	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
GQR50_05270	COG1534	Rna-binding protein
GQR50_05275	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
GQR50_05280	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
GQR50_05285	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
GQR50_05290	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
GQR50_05295	COG0149	triose-phosphate isomerase activity
GQR50_05300	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
GQR50_05315	COG0779	Required for maturation of 30S ribosomal subunits
GQR50_05320	COG0195	Participates in both transcription termination and antitermination
GQR50_05325	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
GQR50_05330	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
GQR50_05335	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
GQR50_05340	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
GQR50_05345	COG1185	polyribonucleotide nucleotidyltransferase activity
GQR50_05350	COG2211	Major facilitator Superfamily
GQR50_05360	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
GQR50_05370	COG0114	fumarate hydratase activity
GQR50_05380	COG1966	Carbon starvation protein
GQR50_05385	COG3279	Response regulator of the LytR AlgR family
GQR50_05390	COG3275	phosphorelay sensor kinase activity
GQR50_05455	COG0312	modulator of DNA gyrase
GQR50_05460	COG0312	modulator of DNA gyrase
GQR50_05465	COG0716	FMN binding
GQR50_05470	COG4974	Belongs to the 'phage' integrase family
GQR50_05475	COG1970	mechanosensitive ion channel activity
GQR50_05480	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
GQR50_05490	COG0789	Transcriptional regulator
GQR50_05505	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
GQR50_05510	COG3545	Serine hydrolase
GQR50_05520	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
GQR50_05530	COG0321	lipoyl(octanoyl) transferase activity
GQR50_05535	COG2921	Belongs to the UPF0250 family
GQR50_05540	COG1686	Belongs to the peptidase S11 family
GQR50_05545	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
GQR50_05550	COG2951	lytic endotransglycosylase activity
GQR50_05555	COG0772	Belongs to the SEDS family
GQR50_05560	COG0772	Belongs to the SEDS family
GQR50_05565	COG0768	penicillin binding
GQR50_05570	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
GQR50_05575	COG0799	negative regulation of ribosome biogenesis
GQR50_05580	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
GQR50_05595	COG0495	leucyl-tRNA aminoacylation
GQR50_05600	COG2888	peptidyl-tyrosine sulfation
GQR50_05605	COG0815	Transfers the fatty acyl group on membrane lipoproteins
GQR50_05610	COG4535	Mg2 and Co2 transporter CorC
GQR50_05615	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
GQR50_05620	COG1702	phosphate starvation-inducible protein PhoH
GQR50_05625	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
GQR50_05630	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
GQR50_05635	COG1335	isochorismatase
GQR50_05645	COG3706	GGDEF domain
GQR50_05660	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
GQR50_05670	COG3706	GGDEF domain
GQR50_05680	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
GQR50_05690	COG3647	Membrane
GQR50_05695	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
GQR50_05705	COG0516	GMP reductase activity
GQR50_05725	COG0642	Histidine kinase
GQR50_05730	COG0745	RESPONSE REGULATOR receiver
GQR50_05760	COG4106	trans-aconitate 2-methyltransferase activity
GQR50_05765	COG3214	Protein conserved in bacteria
GQR50_05790	COG3029	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
GQR50_05795	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
GQR50_05800	COG1053	succinate dehydrogenase
GQR50_05810	COG0584	glycerophosphoryl diester phosphodiesterase
GQR50_05815	COG1511	domain protein
GQR50_05815	COG3264	Mechanosensitive ion channel
GQR50_05825	COG0739	heme binding
GQR50_05840	COG0583	DNA-binding transcription factor activity
GQR50_05860	COG0583	DNA-binding transcription factor activity
GQR50_05865	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
GQR50_05895	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
GQR50_05900	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
GQR50_05910	COG0338	D12 class N6 adenine-specific DNA methyltransferase
GQR50_05920	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
GQR50_05925	COG0546	phosphoglycolate phosphatase activity
GQR50_05930	COG0180	Tryptophanyl-tRNA synthetase
GQR50_05945	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
GQR50_05955	COG1012	belongs to the aldehyde dehydrogenase family
GQR50_05965	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
GQR50_05975	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
GQR50_05975	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
GQR50_05975	COG0674	pyruvate-flavodoxin oxidoreductase activity
GQR50_05975	COG1013	pyruvate-flavodoxin oxidoreductase activity
GQR50_05985	COG0366	Alpha amylase catalytic
GQR50_06015	COG0471	metal ion transport
GQR50_06015	COG0490	domain, Protein
GQR50_06060	COG0012	GTP binding
GQR50_06065	COG0193	aminoacyl-tRNA hydrolase activity
GQR50_06070	COG0737	Belongs to the 5'-nucleotidase family
GQR50_06075	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
GQR50_06085	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
GQR50_06090	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
GQR50_06095	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
GQR50_06100	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
GQR50_06105	COG2890	protein-(glutamine-N5) methyltransferase activity
GQR50_06115	COG2912	Transglutaminase-like superfamily
GQR50_06120	COG2877	3-deoxy-8-phosphooctulonate synthase activity
GQR50_06125	COG1301	dicarboxylic acid transport
GQR50_06135	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
GQR50_06150	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
GQR50_06155	COG1115	amino acid carrier protein
GQR50_06170	COG0714	Associated with various cellular activities
GQR50_06180	COG3104	oligopeptide transport
GQR50_06185	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
GQR50_06190	COG1678	Uncharacterized ACR, COG1678
GQR50_06200	COG0189	ligase activity
GQR50_06205	COG1385	rRNA (uridine-N3-)-methyltransferase activity
GQR50_06215	COG3091	SprT-like family
GQR50_06225	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
GQR50_06250	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
GQR50_06255	COG0739	heme binding
GQR50_06260	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
GQR50_06265	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
GQR50_06265	COG3408	Glycogen debranching enzyme
GQR50_06275	COG1881	PFAM PEBP family protein
GQR50_06285	COG0583	DNA-binding transcription factor activity
GQR50_06295	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
GQR50_06305	COG0583	DNA-binding transcription factor activity
GQR50_06310	COG1028	Short-chain dehydrogenase reductase Sdr
GQR50_06315	COG0616	signal peptide processing
GQR50_06320	COG3724	N-succinylarginine dihydrolase activity
GQR50_06325	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
GQR50_06340	COG0840	transmembrane signaling receptor activity
GQR50_06350	COG2971	BadF BadG BcrA BcrD
GQR50_06360	COG4608	Belongs to the ABC transporter superfamily
GQR50_06365	COG0444	Belongs to the ABC transporter superfamily
GQR50_06370	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GQR50_06375	COG0601	transmembrane transport
GQR50_06380	COG4166	transmembrane transport
GQR50_06415	COG3220	belongs to the UPF0276 family
GQR50_06445	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
GQR50_06450	COG1289	transmembrane transporter activity
GQR50_06460	COG0746	molybdenum cofactor guanylyltransferase activity
GQR50_06470	COG4662	Binding-protein-dependent transport system inner membrane component
GQR50_06480	COG2204	response regulator
GQR50_06485	COG3852	Histidine kinase
GQR50_06490	COG1910	domain protein
GQR50_06495	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
GQR50_06530	COG3383	formate dehydrogenase (NAD+) activity
GQR50_06530	COG3383	formate dehydrogenase (NAD+) activity
GQR50_06535	COG0437	4 iron, 4 sulfur cluster binding
GQR50_06550	COG0281	malic enzyme
GQR50_06570	COG2706	6-phosphogluconolactonase activity
GQR50_06580	COG3264	Mechanosensitive ion channel
GQR50_06580	COG1196	nuclear chromosome segregation
GQR50_06585	COG0469	pyruvate kinase activity
GQR50_06600	COG4651	solute:proton antiporter activity
GQR50_06600	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
GQR50_06610	COG2974	May be involved in recombination
GQR50_06620	COG0420	3'-5' exonuclease activity
GQR50_06625	COG0419	ATPase involved in DNA repair
GQR50_06640	COG3038	cytochrome b561
GQR50_06650	COG0745	RESPONSE REGULATOR receiver
GQR50_06650	COG3706	GGDEF domain
GQR50_06655	COG2190	(PTS) system
GQR50_06665	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
GQR50_06670	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
GQR50_06675	COG0542	response to heat
GQR50_06690	COG1720	tRNA m6t6A37 methyltransferase activity
GQR50_06710	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
GQR50_06715	COG4988	ABC transporter
GQR50_06730	COG0745	RESPONSE REGULATOR receiver
GQR50_06740	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
GQR50_06755	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
GQR50_06760	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
GQR50_06775	COG0083	homoserine kinase activity
GQR50_06780	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
GQR50_06785	COG4319	ketosteroid isomerase
GQR50_06790	COG0488	(ABC) transporter
GQR50_06815	COG0813	purine-nucleoside phosphorylase activity
GQR50_06830	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GQR50_06830	COG2205	protein histidine kinase activity
GQR50_06835	COG3384	dioxygenase
GQR50_06845	COG1283	sodium-dependent phosphate transmembrane transporter activity
GQR50_06855	COG0531	amino acid
GQR50_06860	COG0531	amino acid
GQR50_06875	COG1396	sequence-specific DNA binding
GQR50_06875	COG1917	Cupin 2, conserved barrel domain protein
GQR50_06880	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
GQR50_06900	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
GQR50_06905	COG2375	cellular response to nickel ion
GQR50_06910	COG1538	Outer membrane efflux protein
GQR50_06915	COG0577	efflux transmembrane transporter activity
GQR50_06915	COG1136	(ABC) transporter
GQR50_06920	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GQR50_06930	COG1227	inorganic diphosphatase activity
GQR50_06935	COG0497	DNA recombination
GQR50_06940	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
GQR50_06945	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
GQR50_06950	COG0443	Heat shock 70 kDa protein
GQR50_06955	COG0484	heat shock protein binding
GQR50_06985	COG1285	pathogenesis
GQR50_07000	COG0640	Transcriptional regulator
GQR50_07010	COG2391	methyltransferase activity
GQR50_07030	COG0095	Lipoate-protein ligase
GQR50_07050	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
GQR50_07055	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GQR50_07075	COG0708	Exodeoxyribonuclease III
GQR50_07090	COG2211	Major facilitator Superfamily
GQR50_07135	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
GQR50_07140	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
GQR50_07145	COG1845	cytochrome c oxidase, subunit III
GQR50_07150	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
GQR50_07155	COG0109	protoheme IX farnesyltransferase activity
GQR50_07160	COG2814	Major facilitator Superfamily
GQR50_07170	COG2205	protein histidine kinase activity
GQR50_07170	COG2198	Histidine kinase
GQR50_07170	COG0784	Response regulator, receiver
GQR50_07175	COG1879	ABC-type sugar transport system periplasmic component
GQR50_07185	COG0745	RESPONSE REGULATOR receiver
GQR50_07190	COG3005	denitrification pathway
GQR50_07200	COG3381	protein complex oligomerization
GQR50_07240	COG2003	Belongs to the UPF0758 family
GQR50_07275	COG0583	DNA-binding transcription factor activity
GQR50_07290	COG0549	Belongs to the carbamate kinase family
GQR50_07295	COG1304	FMN binding
GQR50_07300	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
GQR50_07305	COG1335	isochorismatase
GQR50_07320	COG3039	Transposase
GQR50_07345	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
GQR50_07385	COG0159	tryptophan synthase activity
GQR50_07390	COG0133	tryptophan synthase activity
GQR50_07395	COG0134	indole-3-glycerol-phosphate synthase activity
GQR50_07395	COG0135	phosphoribosylanthranilate isomerase activity
GQR50_07400	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
GQR50_07405	COG0512	Glutamine amidotransferase of anthranilate synthase
GQR50_07405	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
GQR50_07410	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
GQR50_07420	COG0009	L-threonylcarbamoyladenylate synthase
GQR50_07430	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
GQR50_07440	COG1946	Acyl-CoA thioesterase
GQR50_07460	COG1309	transcriptional regulator
GQR50_07465	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GQR50_07470	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
GQR50_07475	COG1538	Outer membrane efflux protein
GQR50_07485	COG1091	dTDP-4-dehydrorhamnose reductase activity
GQR50_07510	COG2244	polysaccharide biosynthetic process
GQR50_07530	COG0438	transferase activity, transferring glycosyl groups
GQR50_07535	COG1216	Glycosyl transferase, family 2
GQR50_07535	COG0463	Glycosyl transferase, family 2
GQR50_07540	COG0110	maltose O-acetyltransferase activity
GQR50_07550	COG4641	Protein conserved in bacteria
GQR50_07550	COG0438	transferase activity, transferring glycosyl groups
GQR50_07560	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
GQR50_07595	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
GQR50_07600	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
GQR50_07610	COG3132	Protein of unknown function, DUF480
GQR50_07650	COG1278	Cold shock
GQR50_07675	COG4166	transmembrane transport
GQR50_07680	COG0697	spore germination
GQR50_07685	COG1349	DNA-binding transcription factor activity
GQR50_07695	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
GQR50_07700	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
GQR50_07715	COG1187	pseudouridine synthase activity
GQR50_07730	COG0622	Phosphoesterase
GQR50_07745	COG1261	Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly
GQR50_07750	COG0835	chemotaxis
GQR50_07750	COG0784	Response regulator, receiver
GQR50_07755	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
GQR50_07760	COG1815	bacterial-type flagellum-dependent cell motility
GQR50_07765	COG1558	bacterial-type flagellum-dependent cell motility
GQR50_07780	COG4787	bacterial-type flagellum-dependent cell motility
GQR50_07785	COG4786	Flagellar basal body rod
GQR50_07790	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
GQR50_07795	COG1706	bacterial-type flagellum-dependent cell motility
GQR50_07805	COG1256	bacterial-type flagellum assembly
GQR50_07815	COG2239	Acts as a magnesium transporter
GQR50_07820	COG0248	Ppx GppA phosphatase
GQR50_07825	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
GQR50_07830	COG2716	regulation of RNA biosynthetic process
GQR50_07840	COG2204	response regulator
GQR50_07845	COG3852	Histidine kinase
GQR50_07850	COG2204	response regulator
GQR50_07855	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
GQR50_07860	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
GQR50_07865	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
GQR50_07870	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
GQR50_07890	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
GQR50_07900	COG0590	tRNA wobble adenosine to inosine editing
GQR50_07905	COG0573	inorganic phosphate transmembrane transporter activity
GQR50_07910	COG0581	inorganic phosphate transmembrane transporter activity
GQR50_07920	COG0704	Plays a role in the regulation of phosphate uptake
GQR50_07925	COG1253	flavin adenine dinucleotide binding
GQR50_07940	COG0531	amino acid
GQR50_07960	COG1126	abc transporter atp-binding protein
GQR50_07965	COG0765	amino acid transport
GQR50_07970	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GQR50_07975	COG3706	GGDEF domain
GQR50_07980	COG2271	Major facilitator Superfamily
GQR50_07995	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
GQR50_08020	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
GQR50_08025	COG0477	Major facilitator Superfamily
GQR50_08030	COG0123	including yeast histone deacetylase and acetoin utilization protein
GQR50_08040	COG1199	ATP-dependent helicase activity
GQR50_08055	COG1448	Aminotransferase
GQR50_08060	COG0433	COG0433 Predicted ATPase
GQR50_08075	COG0658	competence protein
GQR50_08075	COG2333	competence protein COMEC
GQR50_08080	COG1132	(ABC) transporter
GQR50_08085	COG1663	tetraacyldisaccharide 4'-kinase activity
GQR50_08090	COG2835	tetraacyldisaccharide 4'-kinase activity
GQR50_08095	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
GQR50_08100	COG2197	response regulator
GQR50_08105	COG0322	excinuclease ABC activity
GQR50_08160	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
GQR50_08165	COG0437	4 iron, 4 sulfur cluster binding
GQR50_08170	COG3301	Polysulphide reductase, NrfD
GQR50_08175	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
GQR50_08185	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
GQR50_08190	COG0215	cysteine-tRNA ligase activity
GQR50_08195	COG3039	Transposase
GQR50_08200	COG2801	Transposase and inactivated derivatives
GQR50_08220	COG1061	Type III restriction enzyme res subunit
GQR50_08230	COG2199	diguanylate cyclase activity
GQR50_08230	COG2203	Gaf domain
GQR50_08260	COG2119	membrane
GQR50_08265	COG0023	Translation Initiation Factor
GQR50_08290	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
GQR50_08305	COG2205	protein histidine kinase activity
GQR50_08305	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GQR50_08315	COG4138	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system
GQR50_08325	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
GQR50_08330	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
GQR50_08335	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
GQR50_08340	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
GQR50_08345	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
GQR50_08355	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
GQR50_08360	COG0505	Belongs to the CarA family
GQR50_08365	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
GQR50_08370	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
GQR50_08405	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GQR50_08410	COG0513	Belongs to the DEAD box helicase family
GQR50_08425	COG4104	PAAR repeat-containing protein
GQR50_08455	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GQR50_08460	COG0765	amino acid transport
GQR50_08465	COG1126	abc transporter atp-binding protein
GQR50_08470	COG0493	'glutamate synthase
GQR50_08475	COG0070	glutamate synthase
GQR50_08475	COG0067	glutamate synthase
GQR50_08475	COG0069	glutamate synthase activity
GQR50_08480	COG1242	4 iron, 4 sulfur cluster binding
GQR50_08535	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
GQR50_08540	COG0574	Belongs to the PEP-utilizing enzyme family
GQR50_08540	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
GQR50_08575	COG3038	cytochrome b561
GQR50_08590	COG1464	Belongs to the NlpA lipoprotein family
GQR50_08595	COG0671	phosphoesterase, PA-phosphatase related
GQR50_08600	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
GQR50_08605	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
GQR50_08615	COG0101	tRNA pseudouridine synthase activity
GQR50_08620	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
GQR50_08625	COG0285	dihydrofolate synthase activity
GQR50_08630	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
GQR50_08635	COG2920	part of a sulfur-relay system
GQR50_08640	COG1289	transmembrane transporter activity
GQR50_08645	COG0670	Belongs to the BI1 family
GQR50_08665	COG2194	sulfuric ester hydrolase activity
GQR50_08675	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
GQR50_08675	COG0392	lysyltransferase activity
GQR50_08685	COG0840	transmembrane signaling receptor activity
GQR50_08690	COG5001	Diguanylate cyclase
GQR50_08695	COG0564	pseudouridine synthase activity
GQR50_08710	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
GQR50_08720	COG0625	glutathione transferase activity
GQR50_08735	COG0367	asparagine synthase
GQR50_08745	COG4651	solute:proton antiporter activity
GQR50_08745	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
GQR50_08750	COG0647	UMP catabolic process
GQR50_08755	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
GQR50_08760	COG1902	pentaerythritol trinitrate reductase activity
GQR50_08765	COG1253	flavin adenine dinucleotide binding
GQR50_08775	COG0247	lactate metabolic process
GQR50_08775	COG0277	FAD linked oxidase domain protein
GQR50_08785	COG2050	protein possibly involved in aromatic compounds catabolism
GQR50_08795	COG2056	Na+-H+ antiporter family
GQR50_08800	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
GQR50_08815	COG0346	lactoylglutathione lyase activity
GQR50_08820	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
GQR50_08830	COG4659	FMN binding
GQR50_08835	COG4658	electron transport chain
GQR50_08845	COG2878	Part of a membrane complex involved in electron transport
GQR50_08850	COG4657	Part of a membrane complex involved in electron transport
GQR50_08855	COG0697	spore germination
GQR50_08870	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
GQR50_08875	COG1288	antiporter activity
GQR50_08880	COG0436	Aminotransferase
GQR50_08890	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
GQR50_08895	COG2027	D-alanyl-D-alanine carboxypeptidase
GQR50_08900	COG1061	Type III restriction enzyme res subunit
GQR50_08905	COG1566	PFAM secretion protein HlyD family protein
GQR50_08915	COG1966	Carbon starvation protein
GQR50_08920	COG3279	Response regulator of the LytR AlgR family
GQR50_08925	COG3275	phosphorelay sensor kinase activity
GQR50_08930	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
GQR50_08930	COG2199	diguanylate cyclase activity
GQR50_08935	COG1454	alcohol dehydrogenase
GQR50_08935	COG1012	belongs to the aldehyde dehydrogenase family
GQR50_08945	COG2095	MarC family integral membrane protein
GQR50_08955	COG0601	transmembrane transport
GQR50_08960	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GQR50_08965	COG0444	Belongs to the ABC transporter superfamily
GQR50_08975	COG0861	Integral membrane protein TerC family
GQR50_08980	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
GQR50_08990	COG1301	dicarboxylic acid transport
GQR50_09005	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
GQR50_09020	COG0537	adenosine 5'-monophosphoramidase activity
GQR50_09055	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
GQR50_09060	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
GQR50_09070	COG2354	Protein conserved in bacteria
GQR50_09085	COG2233	PERMEase
GQR50_09095	COG1252	NADH dehydrogenase
GQR50_09115	COG0393	Putative heavy-metal-binding
GQR50_09125	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
GQR50_09125	COG1648	precorrin-2 dehydrogenase activity
GQR50_09130	COG2221	Nitrite and sulphite reductase 4Fe-4S
GQR50_09145	COG4667	esterase of the alpha-beta hydrolase superfamily
GQR50_09150	COG1619	proteins homologs of microcin C7 resistance protein MccF
GQR50_09155	COG1368	sulfuric ester hydrolase activity
GQR50_09165	COG0527	aspartate kinase activity
GQR50_09170	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
GQR50_09170	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
GQR50_09175	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
GQR50_09195	COG0596	Alpha beta hydrolase
GQR50_09200	COG0346	lactoylglutathione lyase activity
GQR50_09210	COG0583	DNA-binding transcription factor activity
GQR50_09215	COG1620	l-lactate permease
GQR50_09225	COG1139	Iron-sulfur cluster binding protein
GQR50_09265	COG1136	(ABC) transporter
GQR50_09275	COG2814	Major facilitator Superfamily
GQR50_09295	COG0672	)-iron permease
GQR50_09350	COG3039	Transposase
GQR50_09355	COG2203	Gaf domain
GQR50_09355	COG2199	diguanylate cyclase activity
GQR50_09370	COG0393	Putative heavy-metal-binding
GQR50_09420	COG0582	viral genome integration into host DNA
GQR50_09435	COG0659	secondary active sulfate transmembrane transporter activity
GQR50_09450	COG4974	Belongs to the 'phage' integrase family
GQR50_09520	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
GQR50_09525	COG0840	transmembrane signaling receptor activity
GQR50_09535	COG2201	protein-glutamate methylesterase activity
GQR50_09550	COG0840	transmembrane signaling receptor activity
GQR50_09550	COG3290	protein histidine kinase activity
GQR50_09555	COG0643	Histidine kinase
GQR50_09555	COG2198	Histidine kinase
GQR50_09565	COG0745	RESPONSE REGULATOR receiver
GQR50_09570	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
GQR50_09575	COG0437	4 iron, 4 sulfur cluster binding
GQR50_09580	COG5557	Pfam Polysulphide reductase, NrfD
GQR50_09585	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
GQR50_09590	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
GQR50_09595	COG1773	rubredoxin
GQR50_09600	COG0747	negative chemotaxis
GQR50_09605	COG0601	transmembrane transport
GQR50_09610	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GQR50_09620	COG1124	(ABC) transporter
GQR50_09625	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
GQR50_09630	COG0375	protein maturation
GQR50_09635	COG0309	Hydrogenase expression formation protein (HypE)
GQR50_09645	COG0298	carbon dioxide binding
GQR50_09650	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
GQR50_09660	COG1921	L-seryl-tRNASec selenium transferase activity
GQR50_09670	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
GQR50_09680	COG3260	NADH ubiquinone oxidoreductase 20
GQR50_09685	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
GQR50_09690	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
GQR50_09690	COG3261	NADH dehydrogenase
GQR50_09695	COG0650	Formate hydrogenlyase subunit 4
GQR50_09700	COG0651	ATP synthesis coupled electron transport
GQR50_09705	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
GQR50_09710	COG3158	transport of potassium into the cell
GQR50_09725	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
GQR50_09750	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
GQR50_09755	COG0326	Molecular chaperone. Has ATPase activity
GQR50_09760	COG0563	adenylate kinase activity
GQR50_09765	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
GQR50_09775	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GQR50_09790	COG3300	MHYT domain
GQR50_09790	COG5001	Diguanylate cyclase
GQR50_09795	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
GQR50_09815	COG1021	2,3-dihydroxybenzoate-AMP ligase
GQR50_09820	COG1535	isochorismatase
GQR50_09820	COG3433	isochorismatase activity
GQR50_09825	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GQR50_09830	COG1028	Short-chain dehydrogenase reductase Sdr
GQR50_09840	COG0300	oxidoreductase activity
GQR50_09840	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GQR50_09840	COG1028	Short-chain dehydrogenase reductase Sdr
GQR50_09840	COG3321	synthase
GQR50_09840	COG0318	PFAM AMP-dependent synthetase and ligase
GQR50_09850	COG1051	belongs to the nudix hydrolase family
GQR50_09855	COG4235	cytochrome complex assembly
GQR50_09855	COG3088	subunit of a heme lyase
GQR50_09860	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GQR50_09865	COG1138	Cytochrome C-type biogenesis protein
GQR50_09870	COG3301	Polysulphide reductase, NrfD
GQR50_09875	COG0437	4 iron, 4 sulfur cluster binding
GQR50_09880	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
GQR50_09900	COG0247	lactate metabolic process
GQR50_09905	COG3075	Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses fumarate or nitrate as electron acceptor
GQR50_09910	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
GQR50_09915	COG3012	SEC-C Motif Domain Protein
GQR50_09920	COG0840	transmembrane signaling receptor activity
GQR50_09925	COG1846	Transcriptional regulator
GQR50_09925	COG1940	carbohydrate kinase activity
GQR50_09930	COG3290	protein histidine kinase activity
GQR50_09935	COG4565	transcriptional regulatory protein
GQR50_09955	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
GQR50_09960	COG2985	domain, Protein
GQR50_09960	COG0569	domain protein
GQR50_09970	COG0556	nucleotide-excision repair
GQR50_09980	COG0586	Pfam SNARE associated Golgi protein
GQR50_09985	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
GQR50_09990	COG3067	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
GQR50_09995	COG2186	Transcriptional regulator
GQR50_10000	COG2719	SpoVR family
GQR50_10010	COG2766	serine protein kinase
GQR50_10015	COG0514	ATP-dependent DNA helicase (RecQ)
GQR50_10020	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
GQR50_10025	COG0814	amino acid
GQR50_10055	COG0058	SHG alpha-glucan phosphorylase activity
GQR50_10060	COG0471	metal ion transport
GQR50_10065	COG3118	belongs to the thioredoxin family
GQR50_10075	COG1132	(ABC) transporter
GQR50_10085	COG1132	(ABC) transporter
GQR50_10095	COG2501	S4 domain
GQR50_10105	COG3243	poly(R)-hydroxyalkanoic acid synthase
GQR50_10125	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
GQR50_10130	COG2329	Antibiotic biosynthesis monooxygenase
GQR50_10160	COG1742	UPF0060 membrane protein
GQR50_10170	COG0456	acetyltransferase
GQR50_10175	COG0513	Belongs to the DEAD box helicase family
GQR50_10180	COG0386	Belongs to the glutathione peroxidase family
GQR50_10190	COG1181	Belongs to the D-alanine--D-alanine ligase family
GQR50_10205	COG0730	response to heat
GQR50_10210	COG0583	DNA-binding transcription factor activity
GQR50_10225	COG3593	DNA synthesis involved in DNA repair
GQR50_10280	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
GQR50_10285	COG1011	Hydrolase
GQR50_10290	COG1473	amidohydrolase
GQR50_10295	COG0205	6-phosphofructokinase activity
GQR50_10305	COG1434	Gram-negative-bacterium-type cell wall biogenesis
GQR50_10310	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
GQR50_10320	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
GQR50_10325	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
GQR50_10340	COG0242	peptide deformylase activity
GQR50_10385	COG2824	Alkylphosphonate utilization operon protein PhnA
GQR50_10410	COG0406	alpha-ribazole phosphatase activity
GQR50_10415	COG3706	GGDEF domain
GQR50_10425	COG2840	Smr protein MutS2
GQR50_10430	COG2890	protein-(glutamine-N5) methyltransferase activity
GQR50_10435	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
GQR50_10445	COG0513	Belongs to the DEAD box helicase family
GQR50_10450	COG5654	RES domain protein
GQR50_10460	COG0814	amino acid
GQR50_10465	COG1609	Transcriptional regulator
GQR50_10470	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
GQR50_10470	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
GQR50_10475	COG1105	Belongs to the carbohydrate kinase PfkB family
GQR50_10480	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GQR50_10480	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GQR50_10480	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
GQR50_10485	COG2140	Oxalate decarboxylase
GQR50_10490	COG1609	Transcriptional regulator
GQR50_10505	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GQR50_10505	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
GQR50_10510	COG3715	PTS system
GQR50_10515	COG3716	PTS system mannose fructose sorbose family IID component
GQR50_10520	COG2942	2-epimerase
GQR50_10525	COG3313	Fe-S protein
GQR50_10530	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
GQR50_10535	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
GQR50_10540	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
GQR50_10545	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
GQR50_10555	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
GQR50_10575	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
GQR50_10580	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
GQR50_10585	COG0291	Belongs to the bacterial ribosomal protein bL35 family
GQR50_10590	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
GQR50_10595	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
GQR50_10600	COG0072	phenylalanine-tRNA ligase activity
GQR50_10600	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GQR50_10605	COG0776	regulation of translation
GQR50_10625	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
GQR50_10635	COG5001	Diguanylate cyclase
GQR50_10635	COG3300	MHYT domain
GQR50_10640	COG1609	Transcriptional regulator
GQR50_10645	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GQR50_10650	COG1879	ABC-type sugar transport system periplasmic component
GQR50_10655	COG1172	Belongs to the binding-protein-dependent transport system permease family
GQR50_10660	COG1129	ABC transporter
GQR50_10665	COG1869	D-ribose catabolic process
GQR50_10685	COG0037	tRNA processing
GQR50_10690	COG0589	response to stress
GQR50_10695	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
GQR50_10720	COG2010	Cytochrome c
GQR50_10735	COG3278	Belongs to the heme-copper respiratory oxidase family
GQR50_10745	COG1956	GAF domain-containing protein
GQR50_10750	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
GQR50_10760	COG0308	aminopeptidase N
GQR50_10770	COG2902	Dehydrogenase
GQR50_10775	COG0167	dihydroorotate dehydrogenase activity
GQR50_10785	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
GQR50_10785	COG0116	Belongs to the methyltransferase superfamily
GQR50_10795	COG0488	(ABC) transporter
GQR50_10810	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
GQR50_10815	COG1067	ATP-dependent peptidase activity
GQR50_10825	COG4128	Pfam Zonular occludens toxin
GQR50_10860	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
GQR50_10870	COG4128	Pfam Zonular occludens toxin
GQR50_10905	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
GQR50_10945	COG4128	Pfam Zonular occludens toxin
GQR50_10960	COG3141	response to X-ray
GQR50_10970	COG4221	oxidoreductase activity
GQR50_11015	COG0372	Belongs to the citrate synthase family
GQR50_11020	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
GQR50_11030	COG2995	paraquat-inducible protein a
GQR50_11035	COG3008	intermembrane lipid transfer
GQR50_11040	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
GQR50_11040	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
GQR50_11055	COG0084	hydrolase, TatD family'
GQR50_11060	COG0470	DNA polymerase III
GQR50_11065	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
GQR50_11070	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
GQR50_11075	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
GQR50_11080	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
GQR50_11085	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
GQR50_11090	COG1028	Short-chain dehydrogenase reductase Sdr
GQR50_11100	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
GQR50_11105	COG0416	fatty acid biosynthetic process
GQR50_11110	COG0333	Belongs to the bacterial ribosomal protein bL32 family
GQR50_11115	COG1399	metal-binding, possibly nucleic acid-binding protein
GQR50_11130	COG2814	Major facilitator Superfamily
GQR50_11135	COG0424	maF-like protein
GQR50_11140	COG0546	phosphoglycolate phosphatase activity
GQR50_11145	COG0564	pseudouridine synthase activity
GQR50_11150	COG1530	ribonuclease E activity
GQR50_11155	COG0306	phosphate transporter
GQR50_11165	COG0717	Belongs to the dCTP deaminase family
GQR50_11170	COG0572	uridine kinase
GQR50_11175	COG0489	protein tyrosine kinase activity
GQR50_11180	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GQR50_11180	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GQR50_11190	COG0625	glutathione transferase activity
GQR50_11195	COG1254	Belongs to the acylphosphatase family
GQR50_11205	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
GQR50_11220	COG0709	Synthesizes selenophosphate from selenide and ATP
GQR50_11225	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
GQR50_11230	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GQR50_11235	COG3437	response regulator, receiver
GQR50_11245	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
GQR50_11255	COG1643	Atp-dependent helicase
GQR50_11275	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
GQR50_11285	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
GQR50_11290	COG2832	Protein of unknown function (DUF454)
GQR50_11295	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
GQR50_11310	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
GQR50_11315	COG0318	PFAM AMP-dependent synthetase and ligase
GQR50_11320	COG0596	Alpha beta hydrolase
GQR50_11320	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
GQR50_11320	COG2226	methyltransferase
GQR50_11330	COG1214	PFAM Peptidase M22, glycoprotease
GQR50_11340	COG1199	ATP-dependent helicase activity
GQR50_11350	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
GQR50_11355	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
GQR50_11360	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
GQR50_11365	COG0131	Imidazoleglycerol-phosphate dehydratase
GQR50_11365	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
GQR50_11370	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
GQR50_11375	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
GQR50_11380	COG3437	response regulator, receiver
GQR50_11390	COG2205	protein histidine kinase activity
GQR50_11390	COG0784	Response regulator, receiver
GQR50_11390	COG2198	Histidine kinase
GQR50_11395	COG0107	imidazoleglycerol-phosphate synthase activity
GQR50_11400	COG0140	phosphoribosyl-ATP diphosphatase activity
GQR50_11400	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
GQR50_11405	COG0318	PFAM AMP-dependent synthetase and ligase
GQR50_11410	COG1288	antiporter activity
GQR50_11420	COG3134	Outer membrane lipoprotein
GQR50_11430	COG2080	2 iron, 2 sulfur cluster binding
GQR50_11435	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
GQR50_11440	COG1529	Aldehyde oxidase and xanthine dehydrogenase
GQR50_11445	COG2252	PERMEase
GQR50_11450	COG0402	S-adenosylhomocysteine deaminase activity
GQR50_11455	COG2233	PERMEase
GQR50_11460	COG2080	2 iron, 2 sulfur cluster binding
GQR50_11460	COG1529	Aldehyde oxidase and xanthine dehydrogenase
GQR50_11465	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
GQR50_11470	COG0402	S-adenosylhomocysteine deaminase activity
GQR50_11475	COG0493	'glutamate synthase
GQR50_11475	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
GQR50_11480	COG2068	MobA-Related Protein
GQR50_11485	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
GQR50_11490	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
GQR50_11490	COG3608	succinylglutamate desuccinylase aspartoacylase
GQR50_11495	COG0697	spore germination
GQR50_11500	COG0549	Belongs to the carbamate kinase family
GQR50_11510	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
GQR50_11515	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
GQR50_11520	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
GQR50_11535	COG4681	YaeQ
GQR50_11545	COG1024	Enoyl-CoA hydratase
GQR50_11545	COG1250	3-hydroxyacyl-CoA dehydrogenase
GQR50_11550	COG0183	Belongs to the thiolase family
GQR50_11555	COG0714	Associated with various cellular activities
GQR50_11585	COG1595	DNA-templated transcription, initiation
GQR50_11595	COG2067	long-chain fatty acid transport protein
GQR50_11600	COG2067	long-chain fatty acid transport protein
GQR50_11605	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
GQR50_11625	COG3123	guanosine phosphorylase activity
GQR50_11630	COG1760	l-serine dehydratase
GQR50_11635	COG1760	l-serine dehydratase
GQR50_11640	COG2951	lytic endotransglycosylase activity
GQR50_11645	COG3100	YcgL domain-containing protein
GQR50_11650	COG0850	regulation of cytokinetic process
GQR50_11655	COG2894	cell division
GQR50_11660	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
GQR50_11670	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
GQR50_11710	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
GQR50_11715	COG0697	spore germination
GQR50_11720	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
GQR50_11725	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
GQR50_11735	COG0307	riboflavin synthase, alpha
GQR50_11745	COG0534	Mate efflux family protein
GQR50_11775	COG0417	DNA replication proofreading
GQR50_11800	COG1560	Kdo2-lipid A biosynthetic process
GQR50_11805	COG1560	Kdo2-lipid A biosynthetic process
GQR50_11815	COG0583	DNA-binding transcription factor activity
GQR50_11820	COG0673	inositol 2-dehydrogenase activity
GQR50_11825	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
GQR50_11830	COG0583	DNA-binding transcription factor activity
GQR50_11835	COG1028	Short-chain dehydrogenase reductase Sdr
GQR50_11840	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
GQR50_11850	COG3300	MHYT domain
GQR50_11850	COG5001	Diguanylate cyclase
GQR50_11855	COG2723	6-phospho-beta-galactosidase activity
GQR50_11860	COG0583	DNA-binding transcription factor activity
GQR50_11865	COG3706	GGDEF domain
GQR50_11880	COG0667	Aldo Keto reductase
GQR50_11885	COG0583	DNA-binding transcription factor activity
GQR50_11905	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
GQR50_11915	COG2003	Belongs to the UPF0758 family
GQR50_11930	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
GQR50_11965	COG0730	response to heat
GQR50_11975	COG1028	Short-chain dehydrogenase reductase Sdr
GQR50_11985	COG1024	Enoyl-CoA hydratase
GQR50_11990	COG1024	Enoyl-CoA hydratase
GQR50_11995	COG1960	acyl-CoA dehydrogenase activity
GQR50_12005	COG1960	acyl-CoA dehydrogenase activity
GQR50_12010	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
GQR50_12045	COG1584	GPR1 FUN34 yaaH family protein
GQR50_12060	COG1115	amino acid carrier protein
GQR50_12065	COG1024	Enoyl-CoA hydratase
GQR50_12080	COG3162	membrane
GQR50_12085	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GQR50_12090	COG0488	(ABC) transporter
GQR50_12095	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
GQR50_12100	COG0776	regulation of translation
GQR50_12105	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
GQR50_12110	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
GQR50_12115	COG0740	serine-type endopeptidase activity
GQR50_12120	COG0544	peptidyl-prolyl cis-trans isomerase activity
GQR50_12130	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
GQR50_12135	COG4591	ABC-type transport system involved in lipoprotein release permease component
GQR50_12140	COG1136	(ABC) transporter
GQR50_12145	COG4591	ABC-type transport system involved in lipoprotein release permease component
GQR50_12155	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
GQR50_12160	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
GQR50_12165	COG4166	transmembrane transport
GQR50_12170	COG0697	spore germination
GQR50_12180	COG2062	phosphohistidine phosphatase, SixA
GQR50_12230	COG0519	Catalyzes the synthesis of GMP from XMP
GQR50_12230	COG0518	GMP synthase (glutamine-hydrolyzing) activity
GQR50_12235	COG0517	IMP dehydrogenase activity
GQR50_12235	COG0516	GMP reductase activity
GQR50_12240	COG3158	transport of potassium into the cell
GQR50_12260	COG0697	spore germination
GQR50_12265	COG1570	exodeoxyribonuclease VII activity
GQR50_12280	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
GQR50_12285	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
GQR50_12290	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
GQR50_12315	COG0598	Magnesium transport protein CorA
GQR50_12335	COG4771	TonB-dependent receptor
GQR50_12340	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GQR50_12345	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GQR50_12350	COG1120	ATPase activity
GQR50_12360	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
GQR50_12365	COG3033	Beta-eliminating lyase
GQR50_12375	COG3046	protein related to deoxyribodipyrimidine photolyase
GQR50_12380	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
GQR50_12405	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
GQR50_12410	COG0583	DNA-binding transcription factor activity
GQR50_12420	COG4774	siderophore transport
GQR50_12425	COG4977	sequence-specific DNA binding
GQR50_12435	COG0583	DNA-binding transcription factor activity
GQR50_12440	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GQR50_12450	COG0626	cystathionine gamma-synthase activity
GQR50_12455	COG0612	Peptidase, M16
GQR50_12460	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
GQR50_12465	COG2076	Multidrug Resistance protein
GQR50_12470	COG1944	ATP diphosphatase activity
GQR50_12475	COG2116	formate transmembrane transporter activity
GQR50_12480	COG1882	Formate acetyltransferase
GQR50_12485	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
GQR50_12495	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
GQR50_12505	COG1840	ABC-type Fe3 transport system, periplasmic component
GQR50_12510	COG3842	ATPase activity
GQR50_12520	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
GQR50_12525	COG2983	Belongs to the UPF0260 family
GQR50_12540	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
GQR50_12545	COG0045	succinate-CoA ligase (ADP-forming) activity
GQR50_12550	COG0508	dehydrogenase complex catalyzes the overall conversion of
GQR50_12555	COG0567	Dehydrogenase, E1 component
GQR50_12565	COG1053	succinate dehydrogenase
GQR50_12570	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
GQR50_12575	COG2009	succinate dehydrogenase
GQR50_12595	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
GQR50_12600	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
GQR50_12600	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
GQR50_12610	COG3069	C4-dicarboxylate transmembrane transporter activity
GQR50_12625	COG1451	nucleotide metabolic process
GQR50_12640	COG0254	rRNA binding
GQR50_12645	COG0257	Belongs to the bacterial ribosomal protein bL36 family
GQR50_12655	COG0583	DNA-binding transcription factor activity
GQR50_12665	COG1172	Belongs to the binding-protein-dependent transport system permease family
GQR50_12675	COG1879	ABC-type sugar transport system periplasmic component
GQR50_12680	COG1069	ribulokinase activity
GQR50_12690	COG2160	L-arabinose isomerase activity
GQR50_12710	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
GQR50_12715	COG3457	Alanine racemase
GQR50_12730	COG1735	metal-dependent hydrolase with the TIM-barrel fold
GQR50_12735	COG3039	Transposase
GQR50_12740	COG1735	metal-dependent hydrolase with the TIM-barrel fold
GQR50_12750	COG2188	Transcriptional regulator
GQR50_12790	COG2925	Exonuclease
GQR50_12800	COG3345	alpha-galactosidase
GQR50_12805	COG1380	Effector of murein hydrolase LrgA
GQR50_12810	COG1346	cytolysis
GQR50_12815	COG0295	cytidine deaminase activity
GQR50_12820	COG1022	Amp-dependent synthetase and ligase
GQR50_12835	COG0861	Integral membrane protein TerC family
GQR50_12840	COG2885	chlorophyll binding
GQR50_12845	COG2199	diguanylate cyclase activity
GQR50_12865	COG2154	pterin-4-alpha-carbinolamine dehydratase
GQR50_12875	COG3768	UPF0283 membrane protein
GQR50_12880	COG3106	COG3106 Predicted ATPase
GQR50_12895	COG1842	Phage shock protein A
GQR50_12900	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
GQR50_12910	COG4168	peptide transport system, permease
GQR50_12915	COG4171	peptide transport system, permease
GQR50_12925	COG4172	Belongs to the ABC transporter superfamily
GQR50_12935	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
GQR50_12940	COG1286	toxin biosynthetic process
GQR50_12945	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
GQR50_12950	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
GQR50_12955	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
GQR50_12960	COG1674	ftsk spoiiie
GQR50_12960	COG0531	amino acid
GQR50_12970	COG0686	Belongs to the AlaDH PNT family
GQR50_12975	COG0492	ferredoxin-NADP+ reductase activity
GQR50_12980	COG3706	GGDEF domain
GQR50_12985	COG3134	Outer membrane lipoprotein
GQR50_12990	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
GQR50_12995	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
GQR50_13000	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
GQR50_13005	COG0542	response to heat
GQR50_13010	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
GQR50_13015	COG1278	Cold shock
GQR50_13020	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
GQR50_13050	COG3039	Transposase
GQR50_13070	COG3501	Rhs element vgr protein
GQR50_13175	COG3501	Rhs element vgr protein
GQR50_13195	COG3039	Transposase
GQR50_13205	COG2755	lipolytic protein G-D-S-L family
GQR50_13280	COG1435	thymidine kinase activity
GQR50_13285	COG1757	Na H antiporter
GQR50_13290	COG2916	Histone family protein nucleoid-structuring protein H-NS
GQR50_13295	COG2096	Adenosyltransferase
GQR50_13300	COG3530	Putative quorum-sensing-regulated virulence factor
GQR50_13305	COG0602	queuosine metabolic process
GQR50_13310	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
GQR50_13330	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
GQR50_13340	COG0776	regulation of translation
GQR50_13345	COG0539	negative regulation of cytoplasmic translation
GQR50_13350	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
GQR50_13355	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
GQR50_13385	COG0778	Nitroreductase
GQR50_13390	COG5001	Diguanylate cyclase
GQR50_13390	COG3300	MHYT domain
GQR50_13400	COG0583	DNA-binding transcription factor activity
GQR50_13405	COG3437	response regulator, receiver
GQR50_13430	COG4989	oxidoreductase activity
GQR50_13435	COG0724	RNA recognition motif
GQR50_13455	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
GQR50_13510	COG1484	DNA-dependent DNA replication
GQR50_13515	COG4584	PFAM Integrase catalytic
GQR50_13545	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
GQR50_13550	COG1360	Flagellar Motor Protein
GQR50_13555	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
GQR50_13560	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
GQR50_13565	COG0649	NAD binding
GQR50_13565	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
GQR50_13580	COG1034	ATP synthesis coupled electron transport
GQR50_13585	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
GQR50_13590	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
GQR50_13595	COG0839	Belongs to the complex I subunit 6 family
GQR50_13600	COG0713	ATP synthesis coupled electron transport
GQR50_13610	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
GQR50_13615	COG1007	ATP synthesis coupled electron transport
GQR50_13630	COG2199	diguanylate cyclase activity
GQR50_13630	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
GQR50_13635	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
GQR50_13635	COG0047	phosphoribosylformylglycinamidine synthase activity
GQR50_13640	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
GQR50_13645	COG1645	bacterial-type flagellum-dependent swarming motility
GQR50_13650	COG1160	GTP binding
GQR50_13655	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
GQR50_13660	COG2976	Protein conserved in bacteria
GQR50_13665	COG0124	histidyl-tRNA synthetase
GQR50_13670	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
GQR50_13685	COG0820	rRNA (adenine-C2-)-methyltransferase activity
GQR50_13690	COG0105	UTP biosynthetic process
GQR50_13695	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
GQR50_13705	COG0633	Ferredoxin
GQR50_13710	COG0443	Heat shock 70 kDa protein
GQR50_13715	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
GQR50_13725	COG0822	iron-sulfur transferase activity
GQR50_13730	COG1104	cysteine desulfurase activity
GQR50_13775	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
GQR50_13780	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
GQR50_13785	COG1862	Preprotein translocase
GQR50_13790	COG0343	queuine tRNA-ribosyltransferase activity
GQR50_13795	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
GQR50_13800	COG0517	IMP dehydrogenase activity
GQR50_13805	COG0450	alkyl hydroperoxide reductase
GQR50_13810	COG3634	alkyl hydroperoxide reductase activity
GQR50_13830	COG1393	Belongs to the ArsC family
GQR50_13835	COG0798	PFAM Bile acid sodium symporter
GQR50_13840	COG0640	Transcriptional regulator
GQR50_13845	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
GQR50_13845	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
GQR50_13850	COG0509	glycine decarboxylation via glycine cleavage system
GQR50_13855	COG0404	The glycine cleavage system catalyzes the degradation of glycine
GQR50_13860	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
GQR50_13865	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
GQR50_13885	COG2814	Major facilitator Superfamily
GQR50_13890	COG0625	glutathione transferase activity
GQR50_13900	COG0483	inositol monophosphate 1-phosphatase activity
GQR50_13920	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
GQR50_13940	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
GQR50_13950	COG2089	acid synthase
GQR50_13955	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
GQR50_13975	COG1083	cytidylyl-transferase
GQR50_14025	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
GQR50_14025	COG0301	tRNA thio-modification
GQR50_14035	COG4953	penicillin-binding protein 1C
GQR50_14040	COG2373	Large extracellular alpha-helical protein
GQR50_14045	COG0446	pyridine nucleotide-disulphide oxidoreductase
GQR50_14055	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
GQR50_14070	COG4215	(ABC) transporter
GQR50_14075	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GQR50_14085	COG2431	L-lysine efflux transmembrane transporter activity
GQR50_14090	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
GQR50_14095	COG3124	Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP
GQR50_14110	COG1393	Belongs to the ArsC family
GQR50_14120	COG4783	chaperone-mediated protein folding
GQR50_14125	COG0425	Belongs to the sulfur carrier protein TusA family
GQR50_14150	COG3842	ATPase activity
GQR50_14160	COG1175	transmembrane transport
GQR50_14170	COG3081	Nucleoid-associated protein
GQR50_14175	COG3082	Protein of unknown function (DUF1414)
GQR50_14180	COG3083	sulfuric ester hydrolase activity
GQR50_14185	COG4771	TonB-dependent receptor
GQR50_14190	COG1770	oligopeptidase
GQR50_14210	COG4574	serine-type endopeptidase inhibitor activity
GQR50_14215	COG3085	chromosome segregation
GQR50_14220	COG0583	DNA-binding transcription factor activity
GQR50_14225	COG0287	Prephenate dehydrogenase
GQR50_14225	COG1605	Chorismate mutase
GQR50_14230	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
GQR50_14235	COG0584	glycerophosphoryl diester phosphodiesterase
GQR50_14250	COG1349	DNA-binding transcription factor activity
GQR50_14255	COG2271	Major facilitator Superfamily
GQR50_14260	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
GQR50_14265	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
GQR50_14270	COG0583	DNA-binding transcription factor activity
GQR50_14290	COG0656	L-ascorbic acid biosynthetic process
GQR50_14295	COG2814	Major facilitator Superfamily
GQR50_14305	COG1294	oxidase, subunit
GQR50_14310	COG1271	oxidase subunit
GQR50_14315	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GQR50_14330	COG2979	Protein of unknown function (DUF533)
GQR50_14355	COG2271	Major facilitator Superfamily
GQR50_14360	COG0583	DNA-binding transcription factor activity
GQR50_14370	COG2807	transmembrane transport
GQR50_14375	COG1187	pseudouridine synthase activity
GQR50_14395	COG0346	lactoylglutathione lyase activity
GQR50_14405	COG1403	HNH endonuclease
GQR50_14415	COG2964	Protein conserved in bacteria
GQR50_14420	COG3681	Belongs to the UPF0597 family
GQR50_14430	COG0814	amino acid
GQR50_14455	COG1166	arginine decarboxylase activity
GQR50_14465	COG2195	Cleaves the N-terminal amino acid of tripeptides
GQR50_14495	COG0583	DNA-binding transcription factor activity
GQR50_14505	COG2759	Belongs to the formate--tetrahydrofolate ligase family
GQR50_14515	COG0840	transmembrane signaling receptor activity
GQR50_14520	COG0302	gtp cyclohydrolase
GQR50_14530	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
GQR50_14535	COG2267	carboxylic ester hydrolase activity
GQR50_14540	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
GQR50_14555	COG0314	molybdopterin synthase activity
GQR50_14560	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
GQR50_14565	COG0315	cyclic pyranopterin monophosphate synthase activity
GQR50_14570	COG0521	Mo-molybdopterin cofactor biosynthetic process
GQR50_14575	COG3005	denitrification pathway
GQR50_14585	COG0348	domain, Protein
GQR50_14590	COG0437	4 iron, 4 sulfur cluster binding
GQR50_14595	COG0243	molybdopterin cofactor binding
GQR50_14605	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
GQR50_14605	COG1149	4fe-4S ferredoxin, iron-sulfur binding domain protein
GQR50_14610	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
GQR50_14615	COG3850	Histidine kinase
GQR50_14620	COG2197	response regulator
GQR50_14650	COG0121	glutamine amidotransferase
GQR50_14655	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
GQR50_14660	COG1960	acyl-CoA dehydrogenase activity
GQR50_14665	COG3437	response regulator, receiver
GQR50_14665	COG0784	Response regulator, receiver
GQR50_14675	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
GQR50_14680	COG0328	RNA-DNA hybrid ribonuclease activity
GQR50_14685	COG2226	methyltransferase
GQR50_14690	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GQR50_14695	COG0741	lytic transglycosylase activity
GQR50_14695	COG1388	LysM domain
GQR50_14700	COG3021	interspecies interaction between organisms
GQR50_14710	COG1607	acyl-coa hydrolase
GQR50_14715	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GQR50_14725	COG0741	lytic transglycosylase activity
GQR50_14735	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
GQR50_14755	COG2911	Protein conserved in bacteria
GQR50_14760	COG0729	surface antigen
GQR50_14770	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
GQR50_14775	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
GQR50_14785	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
GQR50_14795	COG4134	Bacterial extracellular solute-binding protein
GQR50_14805	COG4136	ATPase activity
GQR50_14810	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
GQR50_14815	COG2951	lytic endotransglycosylase activity
GQR50_14830	COG1846	Transcriptional regulator
GQR50_14840	COG0033	Phosphoglucomutase
GQR50_14845	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
GQR50_14850	COG0596	Alpha beta hydrolase
GQR50_14865	COG0716	FMN binding
GQR50_14875	COG0735	belongs to the Fur family
GQR50_14880	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
GQR50_14890	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GQR50_14890	COG2190	(PTS) system
GQR50_14890	COG1263	PTS System
GQR50_14895	COG0363	glucosamine-6-phosphate deaminase activity
GQR50_14900	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
GQR50_14905	COG1940	carbohydrate kinase activity
GQR50_14905	COG1846	Transcriptional regulator
GQR50_14910	COG2194	sulfuric ester hydrolase activity
GQR50_14915	COG0217	transcriptional regulatory protein
GQR50_14920	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
GQR50_14925	COG1801	Protein of unknown function DUF72
GQR50_14930	COG4106	trans-aconitate 2-methyltransferase activity
GQR50_14935	COG0500	methyltransferase
GQR50_14960	COG0450	alkyl hydroperoxide reductase
GQR50_14965	COG0583	DNA-binding transcription factor activity
GQR50_14975	COG0791	NLP P60 protein
GQR50_14990	COG1309	transcriptional regulator
GQR50_15030	COG0534	Mate efflux family protein
GQR50_15050	COG2366	antibiotic biosynthetic process
GQR50_15055	COG1013	pyruvate-flavodoxin oxidoreductase activity
GQR50_15055	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
GQR50_15055	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
GQR50_15055	COG0674	pyruvate-flavodoxin oxidoreductase activity
GQR50_15065	COG3217	Mosc domain protein beta barrel domain protein
GQR50_15065	COG0633	Ferredoxin
GQR50_15065	COG3217	Mosc domain protein beta barrel domain protein
GQR50_15065	COG0633	Ferredoxin
GQR50_15075	COG0501	Belongs to the peptidase M48B family
GQR50_15080	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
GQR50_15085	COG1073	alpha beta
GQR50_15085	COG2226	methyltransferase
GQR50_15090	COG0156	8-amino-7-oxononanoate synthase activity
GQR50_15095	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
GQR50_15115	COG0017	Asparaginyl-tRNA synthetase
GQR50_15120	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
GQR50_15135	COG3069	C4-dicarboxylate transmembrane transporter activity
GQR50_15145	COG0583	DNA-binding transcription factor activity
GQR50_15150	COG1393	Belongs to the ArsC family
GQR50_15155	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
GQR50_15160	COG1876	peptidase activity
GQR50_15170	COG3263	regulation of cellular component size
GQR50_15190	COG1280	lysine exporter protein (LysE YggA)
GQR50_15220	COG0564	pseudouridine synthase activity
GQR50_15230	COG1454	alcohol dehydrogenase
GQR50_15235	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
GQR50_15240	COG0702	epimerase
GQR50_15250	COG2867	negative regulation of translational initiation
GQR50_15255	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
GQR50_15270	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
GQR50_15275	COG0583	DNA-binding transcription factor activity
GQR50_15280	COG2610	gluconate transmembrane transporter activity
GQR50_15285	COG3048	D-serine ammonia-lyase activity
GQR50_15295	COG0538	isocitrate dehydrogenase activity
GQR50_15300	COG2207	Transcriptional regulator
GQR50_15305	COG1482	cell wall glycoprotein biosynthetic process
GQR50_15320	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GQR50_15335	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
GQR50_15340	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GQR50_15340	COG1263	PTS System
GQR50_15345	COG1609	Transcriptional regulator
GQR50_15360	COG0456	acetyltransferase
GQR50_15370	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GQR50_15370	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
GQR50_15370	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GQR50_15380	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GQR50_15390	COG1187	pseudouridine synthase activity
GQR50_15400	COG0482	sulfurtransferase activity
GQR50_15405	COG2915	High frequency lysogenization protein hflD homolog
GQR50_15410	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
GQR50_15415	COG2850	peptidyl-arginine hydroxylation
GQR50_15420	COG3153	acetyltransferase
GQR50_15430	COG0625	glutathione transferase activity
GQR50_15435	COG0259	pyridoxamine-phosphate oxidase activity
GQR50_15450	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
GQR50_15450	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
GQR50_15455	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
GQR50_15470	COG4235	cytochrome complex assembly
GQR50_15470	COG3088	subunit of a heme lyase
GQR50_15475	COG3088	subunit of a heme lyase
GQR50_15475	COG4235	cytochrome complex assembly
GQR50_15480	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GQR50_15485	COG1138	Cytochrome C-type biogenesis protein
GQR50_15490	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
GQR50_15495	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
GQR50_15500	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
GQR50_15505	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
GQR50_15520	COG0835	chemotaxis
GQR50_15530	COG1192	Involved in chromosome partitioning
GQR50_15535	COG1360	Flagellar Motor Protein
GQR50_15540	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
GQR50_15545	COG2201	protein-glutamate methylesterase activity
GQR50_15550	COG2198	Histidine kinase
GQR50_15550	COG0643	Histidine kinase
GQR50_15555	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
GQR50_15570	COG0455	bacterial-type flagellum organization
GQR50_15580	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
GQR50_15590	COG1684	flagellar biosynthetic protein fliR
GQR50_15595	COG1987	bacterial-type flagellum assembly
GQR50_15645	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
GQR50_15655	COG1677	Flagellar hook-basal body complex protein FliE
GQR50_15670	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
GQR50_15680	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
GQR50_15680	COG3064	Membrane
GQR50_15680	COG1073	alpha beta
GQR50_15685	COG2994	toxin metabolic process
GQR50_15695	COG2274	protein secretion by the type I secretion system
GQR50_15705	COG2274	protein secretion by the type I secretion system
GQR50_15710	COG0745	RESPONSE REGULATOR receiver
GQR50_15725	COG1737	Transcriptional regulator
GQR50_15730	COG0469	pyruvate kinase activity
GQR50_15740	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
GQR50_15745	COG1960	acyl-CoA dehydrogenase activity
GQR50_15755	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
GQR50_15765	COG0243	molybdopterin cofactor binding
GQR50_15770	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
GQR50_15775	COG0583	DNA-binding transcription factor activity
GQR50_15795	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
GQR50_15800	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
GQR50_15805	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
GQR50_15810	COG1012	belongs to the aldehyde dehydrogenase family
GQR50_15810	COG1454	alcohol dehydrogenase
GQR50_15820	COG1012	belongs to the aldehyde dehydrogenase family
GQR50_15820	COG1454	alcohol dehydrogenase
GQR50_15825	COG1882	Formate acetyltransferase
GQR50_15830	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
GQR50_15835	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
GQR50_15840	COG4869	propanediol catabolic process
GQR50_15860	COG0582	viral genome integration into host DNA
GQR50_15870	COG3311	Transcriptional regulator
GQR50_15910	COG4683	PFAM Phage derived protein Gp49-like (DUF891)
GQR50_15920	COG5377	YqaJ viral recombinase family
GQR50_15950	COG2003	Belongs to the UPF0758 family
GQR50_15985	COG0515	serine threonine protein kinase
GQR50_16020	COG1388	LysM domain
GQR50_16020	COG1376	ErfK ybiS ycfS ynhG family protein
GQR50_16035	COG3129	Specifically methylates the adenine in position 1618 of 23S rRNA
GQR50_16045	COG0791	NLP P60 protein
GQR50_16055	COG3118	belongs to the thioredoxin family
GQR50_16065	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
GQR50_16070	COG0788	formyltetrahydrofolate deformylase activity
GQR50_16080	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
GQR50_16100	COG0366	Alpha amylase catalytic
GQR50_16105	COG1196	nuclear chromosome segregation
GQR50_16105	COG0741	lytic transglycosylase activity
GQR50_16105	COG0739	heme binding
GQR50_16110	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
GQR50_16115	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
GQR50_16125	COG0673	inositol 2-dehydrogenase activity
GQR50_16145	COG3152	Membrane
GQR50_16165	COG1032	radical SAM domain protein
GQR50_16175	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
GQR50_16180	COG1566	PFAM secretion protein HlyD family protein
GQR50_16185	COG2203	Gaf domain
GQR50_16185	COG2199	diguanylate cyclase activity
GQR50_16190	COG1752	Esterase of the alpha-beta hydrolase superfamily
GQR50_16195	COG0733	neurotransmitter:sodium symporter activity
GQR50_16225	COG0281	malic enzyme
GQR50_16235	COG0534	Mate efflux family protein
GQR50_16245	COG0745	RESPONSE REGULATOR receiver
GQR50_16245	COG3706	GGDEF domain
GQR50_16250	COG2233	PERMEase
GQR50_16255	COG0095	Lipoate-protein ligase
GQR50_16260	COG1115	amino acid carrier protein
GQR50_16265	COG0019	diaminopimelate decarboxylase activity
GQR50_16275	COG0678	peroxiredoxin activity
GQR50_16290	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
GQR50_16310	COG1131	(ABC) transporter
GQR50_16315	COG0545	Peptidyl-prolyl cis-trans isomerase
GQR50_16320	COG3142	Participates in the control of copper homeostasis
GQR50_16335	COG4783	chaperone-mediated protein folding
GQR50_16345	COG5002	protein histidine kinase activity
GQR50_16350	COG0745	RESPONSE REGULATOR receiver
GQR50_16355	COG0346	lactoylglutathione lyase activity
GQR50_16360	COG1804	L-carnitine dehydratase bile acid-inducible protein F
GQR50_16365	COG1960	acyl-CoA dehydrogenase activity
GQR50_16370	COG3284	Transcriptional regulator
GQR50_16375	COG1012	belongs to the aldehyde dehydrogenase family
GQR50_16385	COG0697	spore germination
GQR50_16390	COG4565	transcriptional regulatory protein
GQR50_16395	COG3290	protein histidine kinase activity
GQR50_16400	COG0281	malic enzyme
GQR50_16415	COG1846	Transcriptional regulator
GQR50_16420	COG1566	PFAM secretion protein HlyD family protein
GQR50_16450	COG0602	queuosine metabolic process
GQR50_16455	COG1328	CTP reductase activity
GQR50_16465	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
GQR50_16470	COG3115	cell septum assembly
GQR50_16475	COG1196	nuclear chromosome segregation
GQR50_16485	COG2860	membrane
GQR50_16495	COG3108	Peptidase M15
GQR50_16500	COG2989	Protein conserved in bacteria
GQR50_16515	COG0463	Glycosyl transferase, family 2
GQR50_16530	COG0366	Alpha amylase catalytic
GQR50_16565	COG3706	GGDEF domain
GQR50_16575	COG3590	peptidase
GQR50_16585	COG0488	(ABC) transporter
GQR50_16595	COG0531	amino acid
GQR50_16610	COG0814	amino acid
GQR50_16625	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
GQR50_16630	COG1982	Orn Lys Arg decarboxylase major
GQR50_16635	COG0531	amino acid
GQR50_16640	COG3710	Transcriptional regulator
GQR50_16645	COG0825	malonyl-CoA metabolic process
GQR50_16655	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
GQR50_16660	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
GQR50_16665	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
GQR50_16670	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
GQR50_16675	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
GQR50_16690	COG0750	zinc metalloprotease
GQR50_16695	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
GQR50_16700	COG0575	Belongs to the CDS family
GQR50_16710	COG0233	cytoplasmic translational termination
GQR50_16715	COG0528	UMP kinase activity
GQR50_16720	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
GQR50_16725	COG0052	Belongs to the universal ribosomal protein uS2 family
GQR50_16730	COG0024	Methionine aminopeptidase
GQR50_16735	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
GQR50_16740	COG2171	N-acyltransferase activity
GQR50_16750	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GQR50_16750	COG1263	PTS System
GQR50_16770	COG0564	pseudouridine synthase activity
GQR50_16775	COG3098	single-species biofilm formation
GQR50_16800	COG5595	Zn-ribbon-containing, possibly nucleic-acid-binding protein (DUF2310)
GQR50_16810	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
GQR50_16810	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
GQR50_16820	COG3706	GGDEF domain
GQR50_16825	COG1611	Belongs to the LOG family
GQR50_16830	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
GQR50_16835	COG0473	3-isopropylmalate dehydrogenase activity
GQR50_16845	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
GQR50_16850	COG2363	Small membrane protein
GQR50_16860	COG0583	DNA-binding transcription factor activity
GQR50_16865	COG0840	transmembrane signaling receptor activity
GQR50_16870	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
GQR50_16885	COG1477	protein flavinylation
GQR50_16890	COG2871	sodium ion transport
GQR50_16895	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
GQR50_16900	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
GQR50_16905	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
GQR50_16910	COG1805	sodium ion transport
GQR50_16915	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
GQR50_16920	COG0271	Belongs to the BolA IbaG family
GQR50_16925	COG2813	Specifically methylates the guanine in position
GQR50_16935	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
GQR50_16945	COG2211	Major facilitator Superfamily
GQR50_16955	COG1666	GTP binding
GQR50_16960	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
GQR50_16965	COG0693	protein deglycase activity
GQR50_17005	COG3501	Rhs element vgr protein
GQR50_17015	COG2771	luxR family
GQR50_17035	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
GQR50_17045	COG1151	hydroxylamine reductase activity
GQR50_17050	COG0783	Belongs to the Dps family
GQR50_17075	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
GQR50_17090	COG4221	oxidoreductase activity
GQR50_17100	COG0415	Belongs to the DNA photolyase family
GQR50_17105	COG0789	Transcriptional regulator
GQR50_17110	COG3272	Protein of unknown function (DUF1722)
GQR50_17140	COG1605	Chorismate mutase
GQR50_17140	COG0077	Prephenate dehydratase
GQR50_17200	COG2132	Multicopper oxidase
GQR50_17225	COG2217	Heavy metal translocating P-type atpase
GQR50_17235	COG5002	protein histidine kinase activity
GQR50_17240	COG0745	RESPONSE REGULATOR receiver
GQR50_17250	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GQR50_17255	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
GQR50_17260	COG1538	Outer membrane efflux protein
GQR50_17270	COG3039	Transposase
GQR50_17300	COG3039	Transposase
GQR50_17330	COG3254	rhamnose metabolic process
GQR50_17340	COG4806	L-rhamnose isomerase
GQR50_17345	COG1070	Carbohydrate kinase
GQR50_17350	COG4977	sequence-specific DNA binding
GQR50_17355	COG1454	alcohol dehydrogenase
GQR50_17360	COG0235	Class ii aldolase
GQR50_17370	COG0840	transmembrane signaling receptor activity
GQR50_17380	COG0300	oxidoreductase activity
GQR50_17405	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
GQR50_17420	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
GQR50_17430	COG0826	peptidase U32
GQR50_17435	COG1280	lysine exporter protein (LysE YggA)
GQR50_17450	COG0840	transmembrane signaling receptor activity
GQR50_17455	COG0745	RESPONSE REGULATOR receiver
GQR50_17465	COG2198	Histidine kinase
GQR50_17465	COG0643	Histidine kinase
GQR50_17475	COG0835	chemotaxis
GQR50_17480	COG0840	transmembrane signaling receptor activity
GQR50_17490	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
GQR50_17495	COG2201	protein-glutamate methylesterase activity
GQR50_17500	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
GQR50_17525	COG2205	protein histidine kinase activity
GQR50_17525	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GQR50_17530	COG2197	response regulator
GQR50_17540	COG3188	usher protein
GQR50_17555	COG2203	Gaf domain
GQR50_17555	COG2200	EAL domain
GQR50_17555	COG2199	diguanylate cyclase activity
GQR50_17565	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
GQR50_17575	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
GQR50_17580	COG0305	Participates in initiation and elongation during chromosome replication
GQR50_17585	COG0305	Participates in initiation and elongation during chromosome replication
GQR50_17600	COG2200	EAL domain
GQR50_17605	COG0737	Belongs to the 5'-nucleotidase family
GQR50_17625	COG2204	response regulator
GQR50_17630	COG0545	Peptidyl-prolyl cis-trans isomerase
GQR50_17640	COG2900	Belongs to the SlyX family
GQR50_17645	COG1047	Peptidyl-prolyl cis-trans
GQR50_17650	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
GQR50_17660	COG0784	Response regulator, receiver
GQR50_17660	COG0835	chemotaxis
GQR50_17665	COG0429	hydrolase of the alpha beta-hydrolase fold
GQR50_17670	COG5001	Diguanylate cyclase
GQR50_17670	COG2203	Gaf domain
GQR50_17670	COG3706	GGDEF domain
GQR50_17670	COG4251	negative regulation of phosphorylation
GQR50_17675	COG3089	Belongs to the UPF0270 family
GQR50_17685	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
GQR50_17690	COG0463	Glycosyl transferase, family 2
GQR50_17695	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
GQR50_17695	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GQR50_17700	COG0726	polysaccharide deacetylase
GQR50_17705	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
GQR50_17710	COG2076	Multidrug Resistance protein
GQR50_17715	COG2076	Multidrug Resistance protein
GQR50_17720	COG3954	Phosphoribulokinase
GQR50_17735	COG1765	OsmC-like protein
GQR50_17740	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
GQR50_17745	COG2226	methyltransferase
GQR50_17750	COG3397	chitin binding
GQR50_17765	COG2202	Pas domain
GQR50_17765	COG2205	protein histidine kinase activity
GQR50_17775	COG3655	Transcriptional regulator
GQR50_17780	COG2814	Major facilitator Superfamily
GQR50_17785	COG4771	TonB-dependent receptor
GQR50_17805	COG0748	coenzyme F420 binding
GQR50_17810	COG3721	Heme iron utilization protein
GQR50_17820	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GQR50_17845	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
GQR50_17850	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
GQR50_17855	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
GQR50_17875	COG0741	lytic transglycosylase activity
GQR50_17880	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
GQR50_17900	COG0488	(ABC) transporter
GQR50_17910	COG2252	PERMEase
GQR50_17915	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
GQR50_17920	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
GQR50_17925	COG3178	'Phosphotransferase
GQR50_17930	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
GQR50_17940	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
GQR50_17945	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
GQR50_17955	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
GQR50_17970	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GQR50_17975	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
GQR50_17990	COG0318	PFAM AMP-dependent synthetase and ligase
GQR50_18000	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
GQR50_18005	COG0211	Belongs to the bacterial ribosomal protein bL27 family
GQR50_18010	COG0261	This protein binds to 23S rRNA in the presence of protein L20
GQR50_18015	COG0142	geranyltranstransferase activity
GQR50_18020	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
GQR50_18025	COG0330	HflC and HflK could
GQR50_18030	COG0330	HflC and HflK could
GQR50_18035	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
GQR50_18040	COG1923	regulation of RNA biosynthetic process
GQR50_18045	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
GQR50_18050	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
GQR50_18060	COG0802	atpase or kinase
GQR50_18065	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
GQR50_18065	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
GQR50_18070	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
GQR50_18085	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
GQR50_18090	COG2011	ABC-type metal ion transport system permease component
GQR50_18095	COG1464	Belongs to the NlpA lipoprotein family
GQR50_18110	COG0840	transmembrane signaling receptor activity
GQR50_18135	COG2198	Histidine kinase
GQR50_18135	COG0784	Response regulator, receiver
GQR50_18135	COG5002	protein histidine kinase activity
GQR50_18155	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
GQR50_18170	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
GQR50_18175	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
GQR50_18185	COG2716	regulation of RNA biosynthetic process
GQR50_18190	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
GQR50_18195	COG3013	Belongs to the UPF0304 family
GQR50_18200	COG3092	negative regulation of chromosome organization
GQR50_18205	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
GQR50_18210	COG0280	phosphate acetyltransferase
GQR50_18210	COG0857	belongs to the CobB CobQ family
GQR50_18225	COG0028	Belongs to the TPP enzyme family
GQR50_18235	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
GQR50_18240	COG0671	phosphoesterase, PA-phosphatase related
GQR50_18250	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
GQR50_18255	COG0473	3-isopropylmalate dehydrogenase activity
GQR50_18260	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
GQR50_18265	COG0066	3-isopropylmalate dehydratase activity
GQR50_18280	COG4143	(ABC) transporter
GQR50_18285	COG1178	ABC-type Fe3 transport system permease component
GQR50_18290	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
GQR50_18295	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
GQR50_18305	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
GQR50_18335	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
GQR50_18340	COG0564	pseudouridine synthase activity
GQR50_18350	COG3300	MHYT domain
GQR50_18350	COG5001	Diguanylate cyclase
GQR50_18360	COG0459	protein refolding
GQR50_18365	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
GQR50_18375	COG3030	protein affecting phage T7 exclusion by the F plasmid
GQR50_18380	COG1027	Aspartate ammonia-lyase
GQR50_18385	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
GQR50_18395	COG0477	Major facilitator Superfamily
GQR50_18405	COG3227	Zinc metalloprotease (Elastase)
GQR50_18410	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GQR50_18415	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GQR50_18425	COG0673	inositol 2-dehydrogenase activity
GQR50_18435	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
GQR50_18440	COG0635	Involved in the biosynthesis of porphyrin-containing compound
GQR50_18445	COG3036	rescue of stalled ribosome
GQR50_18450	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
GQR50_18460	COG0138	bifunctional purine biosynthesis protein purh
GQR50_18465	COG0151	Belongs to the GarS family
GQR50_18515	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
GQR50_18540	COG0582	viral genome integration into host DNA
GQR50_18550	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
GQR50_18555	COG0358	DNA primase activity
GQR50_18560	COG1610	YqeY-like protein
GQR50_18565	COG0828	Belongs to the bacterial ribosomal protein bS21 family
GQR50_18570	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
GQR50_18580	COG1388	LysM domain
GQR50_18580	COG4942	peptidase
GQR50_18585	COG1238	metal cluster binding
GQR50_18590	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
GQR50_18595	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
GQR50_18600	COG0585	pseudouridine synthase activity
GQR50_18610	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
GQR50_18615	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
GQR50_18620	COG0148	phosphopyruvate hydratase activity
GQR50_18625	COG0504	CTP synthase activity
GQR50_18630	COG3956	TIGRFAM MazG family protein
GQR50_18635	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
GQR50_18640	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
GQR50_18650	COG4807	Protein conserved in bacteria
GQR50_18655	COG3023	N-Acetylmuramoyl-L-alanine amidase
GQR50_18660	COG1349	DNA-binding transcription factor activity
GQR50_18670	COG2222	sugar isomerase
GQR50_18675	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GQR50_18685	COG3716	PTS system mannose fructose sorbose family IID component
GQR50_18690	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
GQR50_18695	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
GQR50_18710	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
GQR50_18715	COG1381	Involved in DNA repair and RecF pathway recombination
GQR50_18725	COG0571	ribonuclease III activity
GQR50_18730	COG0681	Belongs to the peptidase S26 family
GQR50_18735	COG0481	GTPase activity
GQR50_18750	COG3073	An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E
GQR50_18755	COG1595	DNA-templated transcription, initiation
GQR50_18760	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
GQR50_18770	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
GQR50_18810	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
GQR50_18820	COG0126	phosphoglycerate kinase activity
GQR50_18825	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
GQR50_18830	COG1940	carbohydrate kinase activity
GQR50_18835	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
GQR50_18850	COG4991	sh3 domain protein
GQR50_18855	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
GQR50_18870	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
GQR50_18875	COG1028	Short-chain dehydrogenase reductase Sdr
GQR50_18890	COG1505	serine-type exopeptidase activity
GQR50_18895	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
GQR50_18900	COG0765	amino acid transport
GQR50_18905	COG0765	amino acid transport
GQR50_18910	COG1126	abc transporter atp-binding protein
GQR50_18915	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GQR50_18920	COG1136	(ABC) transporter
GQR50_18920	COG0577	efflux transmembrane transporter activity
GQR50_18925	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GQR50_18930	COG0745	RESPONSE REGULATOR receiver
GQR50_18935	COG2205	protein histidine kinase activity
GQR50_18940	COG2816	NAD+ diphosphatase activity
GQR50_18975	COG2070	2-Nitropropane dioxygenase
GQR50_19000	COG1912	Pfam S-adenosyl-l-methionine hydroxide adenosyltransferase
GQR50_19025	COG0513	Belongs to the DEAD box helicase family
GQR50_19055	COG0154	amidase activity
GQR50_19060	COG2957	Belongs to the agmatine deiminase family
GQR50_19075	COG1902	pentaerythritol trinitrate reductase activity
GQR50_19080	COG0456	acetyltransferase
GQR50_19110	COG0745	RESPONSE REGULATOR receiver
GQR50_19110	COG3706	GGDEF domain
GQR50_19115	COG5001	Diguanylate cyclase
GQR50_19115	COG3300	MHYT domain
GQR50_19125	COG0714	Associated with various cellular activities
GQR50_19135	COG0456	acetyltransferase
GQR50_19145	COG1022	Amp-dependent synthetase and ligase
GQR50_19155	COG2918	glutathione biosynthetic process
GQR50_19160	COG0612	Peptidase, M16
GQR50_19165	COG1238	metal cluster binding
GQR50_19190	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
GQR50_19195	COG0359	binds to the 23S rRNA
GQR50_19200	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
GQR50_19205	COG0360	Binds together with S18 to 16S ribosomal RNA
GQR50_19210	COG1914	H( )-stimulated, divalent metal cation uptake system
GQR50_19230	COG2153	protein acetylation
GQR50_19245	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
GQR50_19250	COG0557	exoribonuclease II activity
GQR50_19255	COG3706	GGDEF domain
GQR50_19260	COG1854	S-ribosylhomocysteine lyase activity
GQR50_19275	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
GQR50_19275	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
GQR50_19335	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
GQR50_19340	COG1047	Peptidyl-prolyl cis-trans
GQR50_19345	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
GQR50_19350	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
GQR50_19355	COG0196	riboflavin kinase activity
GQR50_19360	COG0728	peptidoglycan biosynthetic process
GQR50_19365	COG0268	Binds directly to 16S ribosomal RNA
GQR50_19370	COG0640	Transcriptional regulator
GQR50_19375	COG0583	DNA-binding transcription factor activity
GQR50_19385	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
GQR50_19390	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
GQR50_19395	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
GQR50_19405	COG1051	belongs to the nudix hydrolase family
GQR50_19410	COG3066	DNA modification
GQR50_19420	COG0335	large ribosomal subunit rRNA binding
GQR50_19425	COG0336	Belongs to the RNA methyltransferase TrmD family
GQR50_19430	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
GQR50_19435	COG0228	four-way junction DNA binding
GQR50_19440	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
GQR50_19445	COG4137	Cytochrome C assembly protein
GQR50_19450	COG4536	flavin adenine dinucleotide binding
GQR50_19460	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
GQR50_19460	COG1017	nitric oxide dioxygenase activity
GQR50_19465	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
GQR50_19470	COG0039	L-malate dehydrogenase activity
GQR50_19475	COG4160	amino acid transport
GQR50_19480	COG4215	(ABC) transporter
GQR50_19485	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GQR50_19490	COG1126	abc transporter atp-binding protein
GQR50_19495	COG1438	arginine binding
GQR50_19500	COG2837	iron assimilation
GQR50_19505	COG3842	ATPase activity
GQR50_19515	COG1840	ABC-type Fe3 transport system, periplasmic component
GQR50_19520	COG0347	Belongs to the P(II) protein family
GQR50_19535	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
GQR50_19540	COG0583	DNA-binding transcription factor activity
GQR50_19555	COG1929	Belongs to the glycerate kinase type-1 family
GQR50_19560	COG2610	gluconate transmembrane transporter activity
GQR50_19565	COG3835	regulator
GQR50_19570	COG3112	Uncharacterised protein family (UPF0231)
GQR50_19585	COG0840	transmembrane signaling receptor activity
GQR50_19590	COG3568	Endonuclease Exonuclease Phosphatase
GQR50_19605	COG0513	Belongs to the DEAD box helicase family
GQR50_19650	COG1448	Aminotransferase
GQR50_19665	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
GQR50_19670	COG1328	CTP reductase activity
GQR50_19690	COG4946	Tricorn protease homolog
GQR50_19690	COG0793	Belongs to the peptidase S41A family
GQR50_19720	COG0840	transmembrane signaling receptor activity
GQR50_19725	COG3397	chitin binding
GQR50_19730	COG0583	DNA-binding transcription factor activity
GQR50_19735	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
GQR50_19740	COG4208	sulfate ABC transporter
GQR50_19745	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
GQR50_19755	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
GQR50_19760	COG3174	membrane
GQR50_19765	COG0110	maltose O-acetyltransferase activity
GQR50_19785	COG0165	Argininosuccinate lyase
GQR50_19790	COG0137	argininosuccinate synthase activity
GQR50_19800	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
GQR50_19805	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
GQR50_19815	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
GQR50_19820	COG0527	aspartate kinase activity
GQR50_19820	COG0460	homoserine dehydrogenase
GQR50_19825	COG0626	cystathionine gamma-synthase activity
GQR50_19835	COG3708	Transcriptional regulator
GQR50_19835	COG2207	Transcriptional regulator
GQR50_19840	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GQR50_19845	COG0814	amino acid
GQR50_19850	COG1218	3'(2'),5'-bisphosphate nucleotidase
GQR50_19855	COG0494	nUDIX hydrolase
GQR50_19860	COG1011	Hydrolase
GQR50_19865	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
GQR50_19880	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
GQR50_19890	COG3156	type II secretion system protein K
GQR50_19895	COG4795	General secretion pathway protein
GQR50_19900	COG2165	general secretion pathway protein
GQR50_19915	COG2165	general secretion pathway protein
GQR50_19920	COG1459	type II secretion system
GQR50_19925	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
GQR50_19935	COG3031	protein transport across the cell outer membrane
GQR50_19945	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
GQR50_19970	COG0456	acetyltransferase
GQR50_19975	COG3133	Outer membrane lipoprotein
GQR50_19990	COG2771	luxR family
GQR50_19995	COG3916	Acyl-homoserine-lactone synthase
GQR50_20005	COG4776	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction
GQR50_20010	COG1309	transcriptional regulator
GQR50_20020	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
GQR50_20020	COG2213	PTS system mannitol-specific
GQR50_20025	COG0246	Mannitol dehydrogenase
GQR50_20030	COG3722	fumarate hydratase activity
GQR50_20035	COG3263	regulation of cellular component size
GQR50_20060	COG1671	Belongs to the UPF0178 family
GQR50_20075	COG1988	membrane-bound metal-dependent
GQR50_20080	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
GQR50_20085	COG0513	Belongs to the DEAD box helicase family
GQR50_20110	COG1575	Belongs to the MenA family. Type 1 subfamily
GQR50_20115	COG1169	isochorismate synthase
GQR50_20120	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
GQR50_20125	COG0596	Alpha beta hydrolase
GQR50_20130	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
GQR50_20135	COG1441	menaquinone biosynthetic process
GQR50_20140	COG0318	PFAM AMP-dependent synthetase and ligase
GQR50_20155	COG3539	Fimbrial protein
GQR50_20160	COG3121	Chaperone
GQR50_20165	COG3188	usher protein
GQR50_20175	COG3539	Fimbrial protein
GQR50_20180	COG3039	Transposase
GQR50_20190	COG3291	Pkd domain containing protein
GQR50_20195	COG2949	membrane
GQR50_20215	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
GQR50_20220	COG5380	lipid catabolic process
GQR50_20245	COG2873	o-acetylhomoserine
GQR50_20255	COG1979	alcohol dehydrogenase
GQR50_20275	COG4221	oxidoreductase activity
GQR50_20295	COG1285	pathogenesis
GQR50_20315	COG1368	sulfuric ester hydrolase activity
GQR50_20320	COG1522	sequence-specific DNA binding
GQR50_20330	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
GQR50_20335	COG1418	mRNA catabolic process
GQR50_20340	COG1058	Belongs to the CinA family
GQR50_20340	COG1546	Belongs to the CinA family
GQR50_20350	COG1129	ABC transporter
GQR50_20350	COG0842	Transport permease protein
GQR50_20365	COG0561	phosphatase activity
GQR50_20370	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
GQR50_20390	COG1011	Hydrolase
GQR50_20405	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
GQR50_20410	COG0019	diaminopimelate decarboxylase activity
GQR50_20420	COG1965	Belongs to the frataxin family
GQR50_20425	COG0400	carboxylic ester hydrolase activity
GQR50_20430	COG3072	Adenylate cyclase
GQR50_20435	COG0181	hydroxymethylbilane synthase activity
GQR50_20445	COG2959	enzyme of heme biosynthesis
GQR50_20460	COG1494	fructose-1,6-bisphosphatase
GQR50_20500	COG1733	regulation of RNA biosynthetic process
GQR50_20520	COG3932	Exopolysaccharide synthesis, ExoD
GQR50_20525	COG0814	amino acid
GQR50_20530	COG3706	GGDEF domain
GQR50_20545	COG3417	Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1B (PBP1b)
GQR50_20560	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
GQR50_20565	COG2022	thiamine diphosphate biosynthetic process
GQR50_20575	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
GQR50_20580	COG0352	thiamine-phosphate diphosphorylase activity
GQR50_20585	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
GQR50_20605	COG0745	RESPONSE REGULATOR receiver
GQR50_20615	COG1114	Component of the transport system for branched-chain amino acids
GQR50_20620	COG0189	ligase activity
GQR50_20645	COG1639	'signal transduction protein
GQR50_20655	COG2321	neutral zinc metallopeptidase
GQR50_20660	COG3700	Belongs to the class B bacterial acid phosphatase family
GQR50_20680	COG1366	Belongs to the anti-sigma-factor antagonist family
GQR50_20685	COG2172	sigma factor antagonist activity
GQR50_20690	COG0784	Response regulator, receiver
GQR50_20690	COG2205	protein histidine kinase activity
GQR50_20690	COG5002	protein histidine kinase activity
GQR50_20695	COG3437	response regulator, receiver
GQR50_20705	COG0477	Major facilitator Superfamily
GQR50_20725	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
GQR50_20730	COG1263	PTS System
GQR50_20730	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GQR50_20750	COG0312	modulator of DNA gyrase
GQR50_20755	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
GQR50_20765	COG3164	Protein of unknown function
GQR50_20770	COG1530	ribonuclease E activity
GQR50_20775	COG0424	maF-like protein
GQR50_20780	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
GQR50_20785	COG1792	Involved in formation and maintenance of cell shape
GQR50_20790	COG1077	Cell shape determining protein MreB Mrl
GQR50_20815	COG4968	Prepilin-type N-terminal cleavage methylation domain
GQR50_20835	COG1459	type II secretion system
GQR50_20840	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
GQR50_20890	COG2199	diguanylate cyclase activity
GQR50_20890	COG2200	EAL domain
GQR50_20895	COG2200	EAL domain
GQR50_20900	COG0387	Pfam Sodium calcium exchanger
GQR50_20905	COG2986	histidine ammonia-lyase
GQR50_20910	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
GQR50_20915	COG0010	Belongs to the arginase family
GQR50_20920	COG1228	amidohydrolase
GQR50_20925	COG2188	Transcriptional regulator
GQR50_20930	COG0288	reversible hydration of carbon dioxide
GQR50_20940	COG2177	Part of the ABC transporter FtsEX involved in
GQR50_20945	COG2884	Cell division ATP-binding protein ftsE
GQR50_20950	COG0552	protein localization to endoplasmic reticulum
GQR50_20955	COG0742	ribosomal rna small subunit methyltransferase
GQR50_20985	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
GQR50_20990	COG0741	lytic transglycosylase activity
GQR50_21010	COG2095	MarC family integral membrane protein
GQR50_21020	COG1301	dicarboxylic acid transport
GQR50_21045	COG3714	YhhN family
GQR50_21075	COG1770	oligopeptidase
GQR50_21090	COG4221	oxidoreductase activity
GQR50_21095	COG0583	DNA-binding transcription factor activity
GQR50_21100	COG2249	NAD(P)H dehydrogenase (quinone) activity
GQR50_21160	COG0203	ribosomal protein L17
GQR50_21165	COG0202	RNA polymerase activity
GQR50_21170	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
GQR50_21175	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
GQR50_21180	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
GQR50_21185	COG0257	Belongs to the bacterial ribosomal protein bL36 family
GQR50_21190	COG0201	protein transport
GQR50_21195	COG0200	Binds to the 23S rRNA
GQR50_21200	COG1841	ribosomal large subunit assembly
GQR50_21205	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
GQR50_21210	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
GQR50_21215	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
GQR50_21220	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
GQR50_21225	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
GQR50_21230	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
GQR50_21235	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
GQR50_21240	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
GQR50_21245	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
GQR50_21250	COG0255	Belongs to the universal ribosomal protein uL29 family
GQR50_21255	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
GQR50_21260	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
GQR50_21265	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
GQR50_21270	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
GQR50_21275	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
GQR50_21280	COG0089	rRNA binding
GQR50_21285	COG0088	Forms part of the polypeptide exit tunnel
GQR50_21290	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
GQR50_21295	COG0051	transcription antitermination factor activity, RNA binding
GQR50_21310	COG0745	RESPONSE REGULATOR receiver
GQR50_21315	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
GQR50_21320	COG2183	response to ionizing radiation
GQR50_21340	COG0596	Alpha beta hydrolase
GQR50_21345	COG1040	competence protein
GQR50_21350	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
GQR50_21350	COG0316	Belongs to the HesB IscA family
GQR50_21355	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
GQR50_21360	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
GQR50_21365	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
GQR50_21370	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
GQR50_21375	COG4942	peptidase
GQR50_21385	COG1609	Transcriptional regulator
GQR50_21390	COG0800	Aldolase
GQR50_21395	COG0129	dihydroxy-acid dehydratase activity
GQR50_21400	COG3265	gluconokinase activity
GQR50_21405	COG2610	gluconate transmembrane transporter activity
GQR50_21410	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
GQR50_21415	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
GQR50_21425	COG0456	acetyltransferase
GQR50_21440	COG1490	D-aminoacyl-tRNA deacylase activity
GQR50_21445	COG1295	ribonuclease BN
GQR50_21450	COG1295	ribonuclease BN
GQR50_21460	COG0174	glutamine synthetase
GQR50_21470	COG3852	Histidine kinase
GQR50_21475	COG2204	response regulator
GQR50_21480	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
GQR50_21485	COG0635	Involved in the biosynthesis of porphyrin-containing compound
GQR50_21495	COG3078	GTPase activator activity
GQR50_21505	COG0218	Necessary for normal cell division and for the maintenance of normal septation
GQR50_21515	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
GQR50_21520	COG0408	coproporphyrinogen oxidase activity
GQR50_21525	COG0009	L-threonylcarbamoyladenylate synthase
GQR50_21535	COG0551	DNA topoisomerase type I activity
GQR50_21540	COG2922	Belongs to the Smg family
GQR50_21545	COG0758	DNA mediated transformation
GQR50_21555	COG0242	peptide deformylase activity
GQR50_21560	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
GQR50_21565	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
GQR50_21565	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
GQR50_21570	COG0569	domain protein
GQR50_21575	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
GQR50_21580	COG1322	Protein conserved in bacteria
GQR50_21600	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GQR50_21605	COG0686	Belongs to the AlaDH PNT family
GQR50_21610	COG0518	GMP synthase (glutamine-hydrolyzing) activity
GQR50_21610	COG0519	Catalyzes the synthesis of GMP from XMP
GQR50_21625	COG1396	sequence-specific DNA binding
GQR50_21630	COG1012	belongs to the aldehyde dehydrogenase family
GQR50_21635	COG2962	Rard protein
GQR50_21645	COG1280	lysine exporter protein (LysE YggA)
GQR50_21655	COG2391	methyltransferase activity
GQR50_21660	COG1280	lysine exporter protein (LysE YggA)
GQR50_21715	COG0501	Belongs to the peptidase M48B family
GQR50_21720	COG0210	DNA helicase
GQR50_21745	COG0583	DNA-binding transcription factor activity
GQR50_21765	COG1262	PFAM Formylglycine-generating sulfatase enzyme
GQR50_21770	COG0385	Bile acid
GQR50_21775	COG0531	amino acid
GQR50_21780	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GQR50_21785	COG0531	amino acid
GQR50_21790	COG2731	YhcH YjgK YiaL family protein
GQR50_21795	COG3250	beta-galactosidase activity
GQR50_21800	COG1609	Transcriptional regulator
GQR50_21835	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
GQR50_21840	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
GQR50_21840	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
GQR50_21845	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
GQR50_21850	COG3074	FtsZ-dependent cytokinesis
GQR50_21860	COG1045	serine acetyltransferase
GQR50_21870	COG0745	RESPONSE REGULATOR receiver
GQR50_21875	COG2205	protein histidine kinase activity
GQR50_21880	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
GQR50_21885	COG0534	Mate efflux family protein
GQR50_21905	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
GQR50_21910	COG2937	Belongs to the GPAT DAPAT family
GQR50_21915	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
GQR50_21920	COG3161	chorismate lyase activity
GQR50_21925	COG1580	Controls the rotational direction of flagella during chemotaxis
GQR50_21945	COG0604	alcohol dehydrogenase
GQR50_21950	COG1609	Transcriptional regulator
GQR50_21970	COG1519	Transferase
GQR50_21975	COG0859	PFAM glycosyl transferase family 9
GQR50_21980	COG0463	Glycosyl transferase, family 2
GQR50_21985	COG0859	PFAM glycosyl transferase family 9
GQR50_21990	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
GQR50_21995	COG2990	Protein conserved in bacteria
GQR50_22000	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
GQR50_22010	COG0267	Belongs to the bacterial ribosomal protein bL33 family
GQR50_22015	COG0227	Belongs to the bacterial ribosomal protein bL28 family
GQR50_22020	COG2003	Belongs to the UPF0758 family
GQR50_22025	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
GQR50_22030	COG0756	dUTP diphosphatase activity
GQR50_22035	COG1309	transcriptional regulator
GQR50_22040	COG0668	transmembrane transport
GQR50_22050	COG0166	Belongs to the GPI family
GQR50_22055	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
GQR50_22060	COG0583	DNA-binding transcription factor activity
GQR50_22075	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GQR50_22075	COG1042	CoA-binding domain protein
GQR50_22075	COG0045	succinate-CoA ligase (ADP-forming) activity
GQR50_22100	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
GQR50_22105	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
GQR50_22110	COG1739	Uncharacterized protein family UPF0029
GQR50_22115	COG0006	proline dipeptidase activity
GQR50_22120	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
GQR50_22125	COG1024	Enoyl-CoA hydratase
GQR50_22125	COG1250	3-hydroxyacyl-CoA dehydrogenase
GQR50_22130	COG0183	Belongs to the thiolase family
GQR50_22135	COG0745	RESPONSE REGULATOR receiver
GQR50_22140	COG2205	protein histidine kinase activity
GQR50_22155	COG0425	Belongs to the sulfur carrier protein TusA family
GQR50_22160	COG0251	oxidation-reduction process
GQR50_22165	COG2885	chlorophyll binding
GQR50_22170	COG1335	isochorismatase
GQR50_22175	COG2818	Glycosylase
GQR50_22180	COG0752	glycyl-tRNA synthetase alpha subunit
GQR50_22185	COG0751	glycine-tRNA ligase activity
GQR50_22195	COG0529	Catalyzes the synthesis of activated sulfate
GQR50_22215	COG0814	amino acid
GQR50_22220	COG0348	domain, Protein
GQR50_22230	COG0446	pyridine nucleotide-disulphide oxidoreductase
GQR50_22235	COG0426	domain, Protein
GQR50_22235	COG1773	rubredoxin
GQR50_22240	COG3604	Transcriptional regulator
GQR50_22245	COG1609	Transcriptional regulator
GQR50_22255	COG0559	Belongs to the binding-protein-dependent transport system permease family
GQR50_22285	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
GQR50_22310	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
GQR50_22320	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
GQR50_22325	COG3118	belongs to the thioredoxin family
GQR50_22330	COG0513	Belongs to the DEAD box helicase family
GQR50_22335	COG0248	Ppx GppA phosphatase
GQR50_22350	COG0742	ribosomal rna small subunit methyltransferase
GQR50_22370	COG0084	hydrolase, TatD family'
GQR50_22375	COG0805	protein transport
GQR50_22380	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
GQR50_22390	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
GQR50_22395	COG3165	ubiquinone biosynthetic process from chorismate
GQR50_22405	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
GQR50_22410	COG0402	S-adenosylhomocysteine deaminase activity
GQR50_22450	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
GQR50_22455	COG0848	biopolymer transport protein
GQR50_22460	COG0811	peptide transport
GQR50_22465	COG0811	peptide transport
GQR50_22475	COG2771	luxR family
GQR50_22480	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
GQR50_22485	COG1349	DNA-binding transcription factor activity
GQR50_22490	COG0745	RESPONSE REGULATOR receiver
GQR50_22495	COG2205	protein histidine kinase activity
GQR50_22505	COG4452	Inner membrane protein CreD
GQR50_22510	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
GQR50_22515	COG0355	proton-transporting ATP synthase activity, rotational mechanism
GQR50_22520	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
GQR50_22525	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
GQR50_22530	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
GQR50_22535	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
GQR50_22540	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
GQR50_22550	COG0356	it plays a direct role in the translocation of protons across the membrane
GQR50_22560	COG1475	DNA binding
GQR50_22565	COG1192	Involved in chromosome partitioning
GQR50_22570	COG0357	Ribosomal RNA small subunit methyltransferase G
GQR50_22575	COG0445	tRNA wobble uridine modification
GQR50_22580	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
GQR50_22585	COG4774	siderophore transport
GQR50_22590	COG4615	Cyclic peptide transporter
GQR50_22595	COG1120	ATPase activity
GQR50_22610	COG3550	peptidyl-serine autophosphorylation
GQR50_22685	COG0732	type I restriction modification DNA specificity domain
GQR50_22710	COG4974	Belongs to the 'phage' integrase family
GQR50_22715	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
GQR50_22720	COG0706	membrane insertase activity
GQR50_22725	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
GQR50_22730	COG0594	ribonuclease P activity
GQR50_22735	COG0230	Belongs to the bacterial ribosomal protein bL34 family