locus-tag	class	description
AS145_00005	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
AS145_00010	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
AS145_00015	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
AS145_00020	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
AS145_00030	ENOG4105D29	Helix-turn-helix type 11 domain protein
AS145_00035	ENOG4108ZNX	Heat shock protein
AS145_00040	ENOG4108ZNX	Heat shock protein
AS145_00045	ENOG4105JKW	Valine--pyruvate aminotransferase
AS145_00060	ENOG4105C2C	drug resistance transporter, Bcr CflA
AS145_00065	ENOG4105EEX	Two component transcriptional regulator (Winged helix family
AS145_00070	ENOG4105C08	Histidine kinase
AS145_00080	ENOG4105C8X	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity)
AS145_00085	ENOG4105D9K	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity)
AS145_00090	ENOG4105DC8	reductase
AS145_00095	ENOG4105BZU	Histidine kinase
AS145_00100	ENOG4105BZS	acriflavin resistance protein
AS145_00105	ENOG410624X	efflux transporter, rnd family, mfp subunit
AS145_00110	ENOG4105Y7M	Transcriptional regulator, TetR family
AS145_00140	ENOG4105CA9	Pyruvate kinase
AS145_00145	ENOG4105CXY	transporter
AS145_00150	ENOG4106JDA	Phosphoglycerate transport regulatory protein PGTC
AS145_00160	ENOG4107TXD	phosphoglycerate transport system transcriptional regulatory protein pgta
AS145_00170	ENOG4105DQF	Hydrolase
AS145_00175	ENOG4108EUD	Lysophospholipase
AS145_00185	ENOG4105FE8	tRNA (Guanosine-2'-O-)-methyltransferase
AS145_00190	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
AS145_00195	ENOG4105VFG	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity)
AS145_00205	ENOG4105DKP	glycosyl transferase, family 9
AS145_00210	ENOG4108W7E	Catalyzes the ATP-dependent phosphorylation of the 3- deoxy-D-manno-octulosonic acid (Kdo) residue in Kdo-lipid IV(A) at the 4-OH position (By similarity)
AS145_00220	ENOG4105EMK	carboxylate amino acid amine transporter
AS145_00245	ENOG4108M6U	Universal stress protein A
AS145_00250	ENOG4105RKW	reductase (By
AS145_00255	ENOG4105BZU	Histidine kinase
AS145_00260	ENOG41090A1	ferritin
AS145_00265	ENOG4105CBX	hi0933 family
AS145_00270	ENOG4105EU0	Major facilitator Superfamily
AS145_00290	ENOG4108N3D	putative enzyme
AS145_00295	ENOG4108NN8	Fimbrial protein
AS145_00300	ENOG4108GWT	fimbrillin MatB
AS145_00305	ENOG4107ZHV	Transcriptional regulator
AS145_00310	ENOG4105BZU	Histidine kinase
AS145_00320	ENOG4108HRK	Histidine kinase
AS145_00325	ENOG4105DY9	regulatoR
AS145_00330	ENOG4105FCD	Major Facilitator
AS145_00335	ENOG4105CY8	phosphoribosylaminoimidazole carboxylase atpase subunit
AS145_00340	ENOG4108UM6	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity)
AS145_00355	ENOG41063Z6	transcriptional regulator, lysR family
AS145_00360	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
AS145_00365	ENOG4105F03	Provides the (R)-glutamate required for cell wall biosynthesis (By similarity)
AS145_00405	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
AS145_00470	ENOG4108YGG	dna repair protein
AS145_00515	ENOG410679B	prophage CP4-57 regulatory protein alpA
AS145_00520	ENOG4108YX2	DNA-binding protein
AS145_00535	ENOG4105VJY	transcriptional regulator
AS145_00540	ENOG4108WC9	type VI secretion system effector, hcp1 family
AS145_00545	ENOG4105CS6	Rhs element vgr protein
AS145_00585	ENOG4105DAX	Pfam:DUF2983
AS145_00645	ENOG4105DFP	Integrase
AS145_00650	ENOG4105CUZ	uba thif-type nad fad binding protein
AS145_00655	ENOG4105P9C	Participates in cysteine desulfuration mediated by SufS. Cysteine desulfuration mobilizes sulfur from L-cysteine to yield L-alanine and constitutes an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules. Functions as a sulfur acceptor for SufS, by mediating the direct transfer of the sulfur atom from the S-sulfanylcysteine of SufS, an intermediate product of cysteine desulfuration process (By similarity)
AS145_00660	ENOG4105C9B	Cysteine desulfurase
AS145_00665	ENOG4105C4R	Atp-dependent dna helicase
AS145_00670	ENOG4105BZU	Histidine kinase
AS145_00675	ENOG4105MPD	Cytochrome
AS145_00680	ENOG4105CPQ	Dehydrogenase
AS145_00685	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
AS145_00690	ENOG41062JF	Transcriptional regulator
AS145_00695	ENOG4105CUI	Catalyzes the interconversion between ADP-D-glycero- beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose (By similarity)
AS145_00710	ENOG4105W1T	Glycosyl Transferase
AS145_00730	ENOG4105DSJ	YicC domain protein
AS145_00735	ENOG4105ED0	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates (By similarity)
AS145_00740	ENOG4107QP2	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
AS145_00760	ENOG4105PC1	Conserved Protein
AS145_00770	ENOG4105E27	serine threonine protein kinase
AS145_00775	ENOG4108Z33	Thiol disulfide Interchange Protein
AS145_00780	ENOG4105S7S	phosphonate abc transporter
AS145_00785	ENOG4108VA1	ABC transporter
AS145_00790	ENOG4105EHI	Phosphonate ABC transporter, periplasmic
AS145_00795	ENOG4107RH7	Nicotinate phosphoribosyltransferase
AS145_00800	ENOG4108RWI	nicotinamidase
AS145_00810	ENOG4105EWC	Purine nucleoside phosphorylase
AS145_00815	ENOG4106HNH	Acyl-transferase
AS145_00820	ENOG4106HNH	Acyl-transferase
AS145_00825	ENOG4105C0P	Mg chelatase subunit ChlI
AS145_00835	ENOG4105P3Y	Acetolactate synthase 2 regulatory subunit
AS145_00840	ENOG4105CM2	brancheD-chain amino acid aminotransferase
AS145_00845	ENOG4105C01	Dihydroxy-acid dehydratase
AS145_00850	ENOG4105C7B	Threonine dehydratase
AS145_00855	ENOG4105UYK	outer membrane protein a
AS145_00865	ENOG4105C25	Primosomal protein n'
AS145_00870	ENOG4105VFB	Binds the 23S rRNA (By similarity)
AS145_00875	ENOG4105CGD	Nad-dependent epimerase dehydratase
AS145_00880	ENOG4105C6K	Malic enzyme
AS145_00890	ENOG4105JJR	Histidine kinase
AS145_00895	ENOG4107EXC	regulatoR
AS145_00900	ENOG4107R9T	Catalyzes the formation of 5-methyl-uridine at position 54 (m5U54) in all tRNAs (By similarity)
AS145_00915	ENOG4107R28	alpha amylase, catalytic region
AS145_00930	ENOG4105R8A	Heat shock protein
AS145_00935	ENOG4105C5I	Dehydrogenase
AS145_00940	ENOG4108RH0	Crea protein
AS145_00955	ENOG4108V7X	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
AS145_00960	ENOG4105CFQ	glutamine synthetase
AS145_00965	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
AS145_00975	ENOG4108HM4	ABC transporter
AS145_00980	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
AS145_00985	ENOG4105F38	ABC transporter, permease
AS145_00990	ENOG4105D38	putrescine abc transporter
AS145_00995	ENOG4108RPX	mosc domain containing protein
AS145_01010	ENOG4108VUY	thioesterase Superfamily protein
AS145_01015	ENOG4105C9U	ATP-dependent DNA helicase RecQ
AS145_01020	ENOG4105N7H	Cytochrome
AS145_01025	ENOG4105CNG	UPF0061 protein
AS145_01035	ENOG4105EX9	Membrane
AS145_01040	ENOG4108YYX	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. Modulates RNA-binding and helicase activities of the degradosome (By similarity)
AS145_01045	ENOG4108NVR	Methyl-accepting chemotaxis
AS145_01050	ENOG4105CJW	magnesium transporter
AS145_01055	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
AS145_01060	ENOG4107V9H	nitrite transporter
AS145_01065	ENOG4105WZK	nitrite reductase NADPH small subunit
AS145_01070	ENOG4107QZF	nitrite reductase NADPH large subunit
AS145_01085	ENOG4105C4N	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis (By similarity)
AS145_01090	ENOG4108R5P	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery (By similarity)
AS145_01100	ENOG4105C75	arginyL-tRNA synthetase
AS145_01110	ENOG4105K6V	RNA polymerase
AS145_01115	ENOG4108NIX	Factor ChrR
AS145_01120	ENOG4105DWR	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity)
AS145_01125	ENOG4105CPC	Aldo Keto reductase
AS145_01130	ENOG4105ENN	converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose (By similarity)
AS145_01135	ENOG4105CRD	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P) (By similarity)
AS145_01140	ENOG4105F0Z	galactose-1-phosphate uridylyltransferase
AS145_01145	ENOG4105CMR	udp-glucose 4-epimerase
AS145_01150	ENOG41060NJ	transcriptional regulator
AS145_01155	ENOG4105CNT	hydrolase family 2
AS145_01165	ENOG4105C2J	ABC transporter
AS145_01170	ENOG4107SDZ	Galactoside transport system permease protein mglC
AS145_01175	ENOG4105C8Q	Methyl-accepting chemotaxis
AS145_01195	ENOG4105C5B	carbamate kinase
AS145_01200	ENOG4105DBV	ornithine carbamoyltransferase
AS145_01205	ENOG4105CSX	c4-dicarboxylate anaerobic carrier
AS145_01210	ENOG410682Y	Regulates arginine biosynthesis genes (By similarity)
AS145_01215	ENOG4108R9M	Involved in allosteric regulation of aspartate carbamoyltransferase (By similarity)
AS145_01220	ENOG4105CXT	aspartate transcarbamylase
AS145_01235	ENOG4105DJ4	phosphatidylserine decarboxylase
AS145_01240	ENOG4105C8Q	Methyl-accepting chemotaxis
AS145_01250	ENOG4105CF7	AraC family transcriptional regulator
AS145_01255	ENOG4108I6A	alcohol dehydrogenase
AS145_01260	ENOG4108IIE	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
AS145_01265	ENOG4105C15	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
AS145_01275	ENOG4105WWK	YheO domain protein
AS145_01280	ENOG4105CEM	UPF0597 protein
AS145_01290	ENOG4107QMW	pyridine nucleotide-disulfide oxidoreductase
AS145_01295	ENOG4106SNF	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AS145_01300	ENOG4105C34	Pseudouridine synthase
AS145_01305	ENOG4105DBW	Multi-copper polyphenol oxidoreductase laccase
AS145_01310	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
AS145_01315	ENOG4107T8T	UPF0173 metal-dependent hydrolase
AS145_01320	ENOG4105CU9	asparagine synthetase A
AS145_01325	ENOG4108VVK	transcriptional Regulator, AsnC
AS145_01340	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
AS145_01345	ENOG410642E	Short chain dehydrogenase
AS145_01355	ENOG4107WP9	Histidine kinase
AS145_01365	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
AS145_01370	ENOG4108UQ5	membrane protein YcdZ
AS145_01380	ENOG4105DQ2	Is probably involved in the electron transfer between its heme and the molybdenum cofactor of the reductase catalytic subunit YedY (By similarity)
AS145_01395	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
AS145_01400	ENOG4105IFJ	Histidine kinase
AS145_01410	ENOG4107QY8	reductase
AS145_01415	ENOG4105CUW	cytochrome C-TYPE protein
AS145_01420	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
AS145_01435	ENOG4105E7U	AraC family transcriptional regulator
AS145_01445	ENOG4107ZYR	domain protein
AS145_01450	ENOG4105D4A	Cell wall formation (By similarity)
AS145_01455	ENOG4105HJX	Biotin- acetyl-CoA-carboxylase ligase
AS145_01460	ENOG4105CS9	pantothenic acid kinase
AS145_01475	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
AS145_01485	ENOG4105PM1	preprotein translocase subunit SecE
AS145_01490	ENOG4105E5V	Participates in transcription elongation, termination and antitermination (By similarity)
AS145_01495	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
AS145_01500	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
AS145_01505	ENOG4108VZM	50s ribosomal protein L10
AS145_01510	ENOG4105KBC	Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity)
AS145_01515	ENOG4108IIJ	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
AS145_01520	ENOG4105D27	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
AS145_01530	ENOG4105WWK	YheO domain protein
AS145_01535	ENOG4105KME	endoribonuclease L-psp
AS145_01545	ENOG4108ZKU	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions (By similarity)
AS145_01550	ENOG4105YKK	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions (By similarity)
AS145_01560	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
AS145_01565	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
AS145_01570	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
AS145_01575	ENOG4108ZI0	d,d-heptose 1,7-bisphosphate phosphatase
AS145_01615	ENOG4105C7N	Xanthine uracil vitamin C permease
AS145_01620	ENOG4105CMT	Dihydroxyacetone kinase
AS145_01625	ENOG4108UTZ	Dihydroxyacetone kinase
AS145_01640	ENOG4108JU9	GAF modulated sigma54 specific transcriptional regulator Fis family
AS145_01645	ENOG4105ETT	transcriptional Regulator, LysR family
AS145_01650	ENOG4105DWY	Agmatine deiminase
AS145_01655	ENOG4105EMU	Dehydrogenase
AS145_01660	ENOG4105IPI	Membrane
AS145_01690	ENOG4105CH6	catalase
AS145_01695	ENOG4105WCN	acetyltransferase
AS145_01715	ENOG4105BZU	Histidine kinase
AS145_01725	ENOG4108IJ6	ABC transporter
AS145_01735	ENOG4105E4X	binding-protein-dependent transport systems inner membrane Component
AS145_01760	ENOG4105CWB	LysR family transcriptional Regulator
AS145_01770	ENOG4105C2I	pirin domain protein
AS145_01775	ENOG4108VBZ	doxx family
AS145_01780	ENOG4105DSY	exodeoxyribonuclease V, gamma
AS145_01785	ENOG4107QKA	exodeoxyribonuclease V beta
AS145_01790	ENOG4107QYX	exodeoxyribonuclease v alpha
AS145_01800	ENOG4105KHA	Glyoxalase Bleomycin resistance protein (Dioxygenase
AS145_01835	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
AS145_01840	ENOG4105E0F	Histidine kinase
AS145_01850	ENOG4105D05	Receptor
AS145_01855	ENOG4105VEQ	Cold shock protein
AS145_01865	ENOG41076HS	cation diffusion facilitator family transporter
AS145_01875	ENOG4108UUM	single-stranded DNA-binding protein
AS145_01880	ENOG41086KC	Transcriptional regulator
AS145_01885	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
AS145_01895	ENOG4105EIF	outer membrane protein W
AS145_01900	ENOG4105C8Q	Methyl-accepting chemotaxis
AS145_01915	ENOG4105SYT	Methylenetetrahydrofolate reductase
AS145_01925	ENOG4105DKK	Benzoate
AS145_01930	ENOG4108JCI	Transcriptional regulator
AS145_01960	ENOG41090HJ	UPF0265 protein
AS145_01970	ENOG4105N42	UPF0307 protein
AS145_01975	ENOG4105CMS	peptidase U62, modulator of DNA gyrase
AS145_01980	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
AS145_01985	ENOG4105VFK	BolA family
AS145_01995	ENOG4105E3I	toluene tolerance
AS145_02000	ENOG4107PE3	Mammalian cell entry related domain protein
AS145_02005	ENOG4105CY3	ABC transporter, permease
AS145_02010	ENOG4105DHJ	ABC, transporter
AS145_02015	ENOG4105C2X	Arabinose 5-phosphate isomerase
AS145_02020	ENOG4108Z4R	3-deoxy-d-manno-octulosonate 8-phosphate phosphatase
AS145_02025	ENOG4108P1K	Required for the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane (By similarity)
AS145_02030	ENOG4105WI0	lipopolysaccharide transport periplasmic protein lptA
AS145_02035	ENOG4108IUZ	ABC transporter
AS145_02040	ENOG4105DTW	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
AS145_02045	ENOG41080QH	sigma 54 modulation protein ribosomal protein S30EA
AS145_02050	ENOG4107RM2	PTS IIA-like nitrogen-regulatory protein PtsN
AS145_02055	ENOG4105C21	Displays ATPase and GTPase activities (By similarity)
AS145_02060	ENOG41080Z8	PHOSPHOCARRIER protein
AS145_02065	ENOG4105EMD	TRANSCRIPTIONal
AS145_02080	ENOG41069H0	dihydroorotase EC 3.5.2.3
AS145_02110	ENOG4105C0H	protease
AS145_02115	ENOG4105C0H	protease
AS145_02125	ENOG4105D6Z	AFG1 family ATPase
AS145_02130	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
AS145_02135	ENOG4108UJD	30S ribosomal protein S9
AS145_02140	ENOG4108R5F	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
AS145_02145	ENOG4105DJ5	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
AS145_02150	ENOG4105EIX	cytochrome c1
AS145_02155	ENOG4107MKT	Stringent starvation protein a
AS145_02160	ENOG4105KB2	stringent starvation protein b
AS145_02165	ENOG4105W4M	Transport-associated protein
AS145_02170	ENOG4105F55	Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate (By similarity)
AS145_02175	ENOG41082RQ	UPF0102 protein
AS145_02180	ENOG4105E1C	Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1A (PBP1a) (By similarity)
AS145_02185	ENOG4105CU0	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity)
AS145_02190	ENOG4108V6E	Cell division protein mraZ
AS145_02195	ENOG4105CGJ	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity)
AS145_02200	ENOG41063Y6	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity)
AS145_02205	ENOG4105CJN	penicillin-binding protein
AS145_02210	ENOG4107EEN	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity)
AS145_02215	ENOG4108EQQ	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein (By similarity)
AS145_02220	ENOG4105CPY	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity)
AS145_02225	ENOG4105DMZ	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity)
AS145_02230	ENOG4105CNI	cell division protein FtsW
AS145_02235	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
AS145_02240	ENOG4105DFU	Cell wall formation (By similarity)
AS145_02245	ENOG4105K7E	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly (By similarity)
AS145_02250	ENOG4105CIT	This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity)
AS145_02255	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
AS145_02260	ENOG4105C7C	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
AS145_02270	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
AS145_02280	ENOG4105EJF	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity)
AS145_02285	ENOG41067SF	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase (By similarity)
AS145_02290	ENOG4105DHA	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity (By similarity)
AS145_02305	ENOG4105D7Q	type ii secretion system
AS145_02310	ENOG4107QHF	type ii secretion system protein e
AS145_02320	ENOG4105D18	nicotinate-nucleotide pyrophosphorylase
AS145_02335	ENOG41073TP	transcriptional regulator
AS145_02340	ENOG4105DAQ	Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) (By similarity)
AS145_02345	ENOG4107QSN	dihydrolipoamide acetyltransferase
AS145_02350	ENOG4107QN2	dihydrolipoyl dehydrogenase
AS145_02355	ENOG4105BZU	Histidine kinase
AS145_02365	ENOG4108N3W	hemolysin secretion protein
AS145_02370	ENOG4108N3W	hemolysin secretion protein
AS145_02375	ENOG4105D78	K07001 NTE family protein
AS145_02380	ENOG4107QIJ	Aconitate hydratase 2
AS145_02395	ENOG4105E82	cytochrome subunit of dehydrogenase
AS145_02405	ENOG4105CKI	cobalamin synthesis protein
AS145_02410	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
AS145_02420	ENOG4105K8U	2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
AS145_02425	ENOG4107ZVW	dihydroneopterin aldolase
AS145_02430	ENOG4105K7Z	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP (By similarity)
AS145_02470	ENOG4105DWD	nucleoside recognition domain protein
AS145_02475	ENOG4107R88	Chemotaxis protein (CheV)
AS145_02480	ENOG410904N	short-chain dehydrogenase reductase
AS145_02485	ENOG4105E0I	Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of tRNA(Met), by using acetyl-CoA as an acetyl donor and ATP (or GTP) (By similarity)
AS145_02500	ENOG4108UQY	Iron-storage protein
AS145_02510	ENOG4108Z5K	methylglyoxal synthase
AS145_02525	ENOG4105HDK	L-asparaginase
AS145_02540	ENOG4105D4X	repressor
AS145_02545	ENOG4105C5Y	PTS System
AS145_02550	ENOG4105CG3	alpha amylase, catalytic region
AS145_02555	ENOG4108UW5	maltose o-acetyltransferase
AS145_02565	ENOG4107AQZ	Membrane
AS145_02575	ENOG4105C26	Dehydrogenase
AS145_02580	ENOG4105NRK	Binding-protein-dependent transport systems, inner membrane component
AS145_02585	ENOG4105D81	ABC transporter, permease
AS145_02590	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
AS145_02595	ENOG4107TYH	extracellular solute-binding protein family 1
AS145_02600	ENOG4108M0I	Transcriptional regulator
AS145_02605	ENOG4105DFD	Na H antiporter
AS145_02650	ENOG4105CXW	Synthesizes alpha-1,4-glucan chains using ADP-glucose (By similarity)
AS145_02655	ENOG4107QQ4	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans (By similarity)
AS145_02660	ENOG4105D8J	Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle (By similarity)
AS145_02665	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
AS145_02680	ENOG4107VXZ	Hydrolase
AS145_02685	ENOG4105KW8	RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity)
AS145_02690	ENOG4105F1S	paraquat-inducible protein a
AS145_02695	ENOG4105DY2	Paraquat-inducible protein b
AS145_02700	ENOG4108Q2G	(LipO)protein
AS145_02705	ENOG4105UYK	outer membrane protein a
AS145_02720	ENOG4105H4F	exported protein
AS145_02730	ENOG4105KMG	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes (By similarity)
AS145_02735	ENOG4105CEN	a g-specific adenine glycosylase
AS145_02755	ENOG4105D4J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
AS145_02770	ENOG41067MG	lrgb family
AS145_02780	ENOG4105CMU	LysR family (Transcriptional regulator
AS145_02805	ENOG4108Z66	YbaK ebsC protein
AS145_02810	ENOG4105CJ3	phosphate transporter
AS145_02815	ENOG4107IX6	phosphate transport regulator
AS145_02830	ENOG4105D1S	lipid A biosynthesis
AS145_02835	ENOG4105DW0	Catalyzes the ADP transfer to D-glycero-D-manno-heptose 1-phosphate, yielding ADP-D,D-heptose (By similarity)
AS145_02840	ENOG4105DFG	type I secretion outer membrane protein
AS145_02845	ENOG41087AY	ADP-Ribose pyrophosphatase
AS145_02850	ENOG4108SX3	cytoplasmic protein
AS145_02855	ENOG41070EG	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes (By similarity)
AS145_02860	ENOG4105IPS	esterase
AS145_02880	ENOG4105Y49	secretion protein, HlyD family
AS145_02885	ENOG4105DSW	Fusaric acid resistance protein
AS145_02890	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
AS145_02895	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
AS145_02930	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
AS145_02935	ENOG4105N2G	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
AS145_02960	ENOG4107S7E	1-acyl-sn-glycerol-3-phosphate acyltransferase
AS145_02965	ENOG41087YS	Phage shock protein A
AS145_02980	ENOG41082IR	Excinuclease ABC C subunit domain protein
AS145_02990	ENOG4105FR1	rard protein
AS145_02995	ENOG4108RG0	uracil-dna glycosylase
AS145_03010	ENOG4105FAV	ABC, transporter
AS145_03015	ENOG4105FDK	ABC transporter
AS145_03020	ENOG4105NXV	High-affinity zinc uptake system protein
AS145_03040	ENOG4105DR5	peptidase
AS145_03050	ENOG4105R2J	Conserved Protein
AS145_03070	ENOG4105D86	that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity)
AS145_03075	ENOG4105DFP	Integrase
AS145_03090	ENOG4107TH8	cina domain protein
AS145_03095	ENOG4105C68	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity)
AS145_03105	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
AS145_03110	ENOG4105CFH	Aspartokinase
AS145_03115	ENOG4105VM8	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding (By similarity)
AS145_03170	ENOG41061WM	D-Alanyl-D-Alanine
AS145_03175	ENOG4106W5V	Membrane
AS145_03185	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
AS145_03190	ENOG4105MYG	DNA polymerase iii, chi subunit
AS145_03195	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
AS145_03200	ENOG4108M8S	permease YjgP YjgQ family protein
AS145_03205	ENOG4108K5H	permease YjgP YjgQ family protein
AS145_03220	ENOG4105DFP	Integrase
AS145_03235	ENOG4105XB7	anti-repressor protein
AS145_03260	ENOG4105BZU	Histidine kinase
AS145_03265	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
AS145_03275	ENOG4105EYA	deoxyribonuclease
AS145_03280	ENOG4105D9N	nucleoside
AS145_03290	ENOG4105FCI	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate (By similarity)
AS145_03295	ENOG4105CMW	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis (By similarity)
AS145_03300	ENOG4105CZG	Phosphotransfer between the C1 and C5 carbon atoms of pentose (By similarity)
AS145_03305	ENOG4105D3A	purine nucleoside phosphorylase DeoD-type
AS145_03310	ENOG4105BZU	Histidine kinase
AS145_03320	ENOG4105EAC	phosphoserine phosphatase
AS145_03335	ENOG4105DNJ	May play a role in the repair of endogenous alkylation damage (By similarity)
AS145_03345	ENOG4108ZVW	Anti-RNA polymerase sigma 70 factor
AS145_03350	ENOG4105K70	DNA-binding protein
AS145_03360	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
AS145_03380	ENOG4105CWM	branched-chain amino acid transport system II carrier protein
AS145_03385	ENOG4105CWM	branched-chain amino acid transport system II carrier protein
AS145_03390	ENOG4107S47	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC) (By similarity)
AS145_03395	ENOG4105C1J	atp-dependent rna helicase
AS145_03400	ENOG4105D1Q	UPF0246 protein
AS145_03405	ENOG4105CZX	twitching motility protein
AS145_03410	ENOG4105CZX	twitching motility protein
AS145_03415	ENOG4105DFA	alanine racemase domain protein
AS145_03420	ENOG4105II7	pyrroline-5-carboxylate reductase
AS145_03425	ENOG4108VIA	integral membrane protein
AS145_03430	ENOG4105VZ9	UPF0235 protein
AS145_03445	ENOG4107QSI	ABC, transporter
AS145_03455	ENOG4105EQK	-acetyltransferase
AS145_03460	ENOG4106WH9	Protein of unknown function (DUF2753)
AS145_03465	ENOG4105E39	Enoyl-CoA hydratase
AS145_03480	ENOG4108RZ4	Short-chain dehydrogenase reductase Sdr
AS145_03485	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
AS145_03490	ENOG4105C8Q	Methyl-accepting chemotaxis
AS145_03495	ENOG4105KA4	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity)
AS145_03500	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
AS145_03505	ENOG4105C4M	(Ubiquinol oxidase) subunit I
AS145_03510	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
AS145_03520	ENOG4105KJB	cyd operon protein YbgE
AS145_03525	ENOG4107YD3	Thioesterase
AS145_03530	ENOG4105E02	MotA TolQ exbB proton channel
AS145_03535	ENOG4105M8F	Biopolymer transport protein exbD tolR
AS145_03545	ENOG4107R6Y	Involved in the TonB-independent uptake of proteins (By similarity)
AS145_03550	ENOG4105KCK	Peptidoglycan-associated lipoprotein
AS145_03555	ENOG4105UFD	tol-pal system protein YbgF
AS145_03610	ENOG4105C8Q	Methyl-accepting chemotaxis
AS145_03615	ENOG4105D0I	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate (By similarity)
AS145_03620	ENOG4105DSB	aldose 1-epimerase
AS145_03630	ENOG4107RTM	4-alpha-glucanotransferase (EC 2.4.1.25)
AS145_03635	ENOG4105C9C	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity)
AS145_03645	ENOG4105E0X	reductase
AS145_03655	ENOG4105EJF	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity)
AS145_03660	ENOG4105CJH	Alcohol dehydrogenase zinc-binding domain protein
AS145_03665	ENOG4108ZHJ	Organic hydroperoxide resistance protein
AS145_03670	ENOG4105K56	Transcriptional regulator
AS145_03685	ENOG4105EW9	transcriptional regulator AsnC family
AS145_03700	ENOG4108K4B	hydrolase
AS145_03715	ENOG4105C8J	)-transporter
AS145_03725	ENOG4105C8J	)-transporter
AS145_03750	ENOG4107SQD	Transcriptional regulator, GntR family
AS145_03770	ENOG4105E3B	Multicopper oxidase
AS145_03780	ENOG4105XEP	YhcH YjgK YiaL family protein
AS145_03790	ENOG4105CUY	Mechanosensitive ion channel
AS145_03795	ENOG4107N1Q	ErfK YbiS YcfS YnhG family protein
AS145_03800	ENOG4105CK7	Sodium proline symporter
AS145_03835	ENOG4105EQ2	LysR family Transcriptional regulator
AS145_03840	ENOG4105D6S	protein involved in catabolism of external DNA
AS145_03850	ENOG4105C5H	ABC transporter
AS145_03855	ENOG4105C2X	Arabinose 5-phosphate isomerase
AS145_03860	ENOG4105G5H	Membrane
AS145_03865	ENOG4107QX8	SPFH domain, Band 7 family protein
AS145_03870	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
AS145_03875	ENOG4105C11	sulfate adenylyltransferase), subunit 2
AS145_03880	ENOG4105C3T	may be the GTPase, regulating ATP sulfurylase activity (By similarity)
AS145_03890	ENOG4108I67	Catalyzes the synthesis of activated sulfate (By similarity)
AS145_03910	ENOG4107RHT	methyl-accepting chemotaxis sensory transducer with Pas Pac sensor
AS145_03945	ENOG4108UUE	Transcriptional regulator
AS145_03960	ENOG4105F0N	pyrophosphate phospho-hydrolase
AS145_03965	ENOG4105DFU	Cell wall formation (By similarity)
AS145_03970	ENOG4108UMA	3-octaprenyl-4-hydroxybenzoate carboxy-lyase
AS145_03975	ENOG410630P	Transcriptional regulator
AS145_03980	ENOG4108UGV	hypoxanthine phosphoribosyltransferase
AS145_03985	ENOG4105DA5	(ABC) transporter
AS145_03990	ENOG4105E3A	(ABC) transporter
AS145_03995	ENOG4105DCU	2-hydroxyglutaryl-CoA dehydratase
AS145_04000	ENOG4105CIZ	coA-substrate-specific enzyme activase
AS145_04020	ENOG4108IAA	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate (By similarity)
AS145_04025	ENOG4105CCG	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is tranferred onto alpha-ketoisovalerate to form ketopantoate (By similarity)
AS145_04030	ENOG4105K8U	2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
AS145_04035	ENOG4105DJ0	Poly(A) Polymerase
AS145_04040	ENOG4106F3G	Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon (By similarity)
AS145_04045	ENOG4108V7X	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
AS145_04050	ENOG4105PW4	Sugar fermentation stimulation protein homolog
AS145_04060	ENOG4105CQ7	ATP-dependent helicase
AS145_04065	ENOG4105BZ4	penicillin-binding protein
AS145_04070	ENOG4108YZK	glyoxalase bleomycin resistance protein dioxygenase
AS145_04075	ENOG4108ZBZ	Catalyzes the excretion of spermidine (By similarity)
AS145_04080	ENOG41090TI	Catalyzes the excretion of spermidine (By similarity)
AS145_04090	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
AS145_04100	ENOG41076MN	Phosphoesterase, PA-phosphatase related
AS145_04115	ENOG4105CDM	Glutamate-1-semialdehyde aminotransferase
AS145_04120	ENOG4105CMQ	Chloride channel
AS145_04130	ENOG4108YX9	iron--sulfur cluster insertion protein erpA
AS145_04155	ENOG4108NIW	Leucine export protein LeuE
AS145_04160	ENOG4105VY0	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters (By similarity)
AS145_04165	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
AS145_04175	ENOG4107V40	secretion protein, HlyD family
AS145_04205	ENOG4105I93	response regulator
AS145_04210	ENOG4105DUX	Transporter
AS145_04215	ENOG4105C3Y	UTP-glucose-1-phosphate uridylyltransferase
AS145_04220	ENOG41083P1	competence protein ComEA helix-hairpin-helix repeat protein
AS145_04225	ENOG4108RNI	3'(2')5'-bisphosphate nucleotidase
AS145_04230	ENOG4105K9H	YciI-like protein
AS145_04235	ENOG4107835	probably involved in intracellular septation (By similarity)
AS145_04240	ENOG4105DY8	decarboxylase
AS145_04245	ENOG4108UT2	hemolysin iii
AS145_04250	ENOG4105D0C	transport protein
AS145_04260	ENOG4107R88	Chemotaxis protein (CheV)
AS145_04265	ENOG4108UJV	acyl-CoA thioesterase i
AS145_04270	ENOG4108I0Y	(ABC) transporter
AS145_04275	ENOG4105CV6	ABC transporter, permease
AS145_04280	ENOG4105ECP	epimerase
AS145_04285	ENOG4105BZU	Histidine kinase
AS145_04290	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
AS145_04295	ENOG4105IIU	Aminopeptidase
AS145_04300	ENOG4105CZ1	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity)
AS145_04305	ENOG41090ED	Protein with unknown function (DUF469)
AS145_04310	ENOG4105CSV	Glutaminase
AS145_04315	ENOG4107RM6	sulfurtransferase
AS145_04320	ENOG4105RX7	peptidase S8 and S53, subtilisin, kexin, sedolisin
AS145_04325	ENOG4105SUV	lipoprotein YgdR
AS145_04330	ENOG4105BZ1	(ABC) transporter
AS145_04350	ENOG4107G87	m6 family metalloprotease domain protein
AS145_04355	ENOG4105KQT	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome (By similarity)
AS145_04360	ENOG4105BZU	Histidine kinase
AS145_04380	ENOG4105VYA	Uncharacterized conserved protein (DUF2132)
AS145_04385	ENOG4105DJ4	phosphatidylserine decarboxylase
AS145_04390	ENOG4105E06	May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity)
AS145_04395	ENOG4108RBP	3'-to-5' exoribonuclease specific for small oligoribonucleotides (By similarity)
AS145_04425	ENOG4105VEQ	Cold shock protein
AS145_04435	ENOG4105C8Q	Methyl-accepting chemotaxis
AS145_04440	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
AS145_04445	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
AS145_04515	ENOG4109015	Biopolymer transport protein exbD tolR
AS145_04535	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
AS145_04540	ENOG4108I5X	binding-protein-dependent transport systems inner membrane Component
AS145_04545	ENOG4108IYQ	Binding-protein-dependent transport systems inner membrane component
AS145_04560	ENOG4108JQ7	(ABC) transporter
AS145_04565	ENOG4105CIN	aminoacyl-histidine dipeptidase
AS145_04570	ENOG4105DYA	Acts on guanine, xanthine and to a lesser extent hypoxanthine (By similarity)
AS145_04575	ENOG4105V1F	Fermentation respiration switch protein
AS145_04580	ENOG4108UVK	Binds to the sigma-S subunit of RNA polymerase, activating expression of sigma-S-regulated genes. Stimulates RNA polymerase holoenzyme formation and may bind to several other sigma factors, such as sigma-70 and sigma-32 (By similarity)
AS145_04590	ENOG4105C2S	Catalyzes the NADPH dependent reduction of L-gamma- glutamyl 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate (By similarity)
AS145_04620	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
AS145_04630	ENOG4105D7T	ABC transporter
AS145_04635	ENOG4105DG7	nitrate ABC transporter
AS145_04640	ENOG4105D7T	ABC transporter
AS145_04645	ENOG4107QZF	nitrite reductase NADPH large subunit
AS145_04650	ENOG4107QZF	nitrite reductase NADPH large subunit
AS145_04655	ENOG4105DD7	kinase (PfkB family
AS145_04660	ENOG4105D53	Catalyzes the hydrolysis of pseudouridine 5'-phosphate (PsiMP) to ribose 5-phosphate and uracil (By similarity)
AS145_04670	ENOG4105CA0	peroxidase
AS145_04705	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
AS145_04735	ENOG4105C84	Histidine ammonia-lyase
AS145_04760	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
AS145_04770	ENOG4105C2D	reductase
AS145_04775	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
AS145_04785	ENOG4108RIR	Molybdenum cofactor biosynthesis protein
AS145_04795	ENOG4105DWK	Membrane
AS145_04800	ENOG4107XM3	UPF0442 protein
AS145_04810	ENOG4108IJ7	Glycine betaine
AS145_04815	ENOG4108HQS	Glycine betaine
AS145_04820	ENOG4105GIJ	Glycine betaine
AS145_04825	ENOG4105ET3	Reduction of activated sulfate into sulfite (By similarity)
AS145_04830	ENOG4105ET1	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate (By similarity)
AS145_04835	ENOG4107EER	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity)
AS145_04840	ENOG4107TIF	Phenazine biosynthesis protein, PhzF family
AS145_04845	ENOG4105CRK	lysyL-tRNA synthetase
AS145_04850	ENOG4105CG1	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA (By similarity)
AS145_04855	ENOG4105C8Q	Methyl-accepting chemotaxis
AS145_04860	ENOG4105D6U	Sodium Glutamate Symporter
AS145_04865	ENOG4105HDK	L-asparaginase
AS145_04870	ENOG4105VUT	cytoplasmic protein
AS145_04890	ENOG4105D07	Signal peptide peptidase, SppA
AS145_04895	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
AS145_04900	ENOG41069NU	Nitroreductase
AS145_04915	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
AS145_04920	ENOG4105CIS	alcohol dehydrogenase
AS145_04925	ENOG4105HEI	LysR family (Transcriptional regulator
AS145_04930	ENOG4105CI1	PTS System
AS145_04935	ENOG4108IA2	Sodium pantothenate symporter
AS145_04945	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
AS145_04950	ENOG4105KM4	Acetyl-CoA carboxylase, biotin carboxyl carrier protein
AS145_04955	ENOG4108Z38	Catalyzes a trans-dehydration via an enolate intermediate (By similarity)
AS145_04960	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
AS145_04970	ENOG4105BZU	Histidine kinase
AS145_04990	ENOG4109039	Involved in the biogenesis of TorA. Acts on TorA before the insertion of the molybdenum cofactor and, as a result, probably favors a conformation of the apoenzyme that is competent for acquiring the cofactor (By similarity)
AS145_05005	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
AS145_05020	ENOG4108Z11	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes (By similarity)
AS145_05025	ENOG4105D1W	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity)
AS145_05045	ENOG4108UTT	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity)
AS145_05050	ENOG4107YIM	Involved in the transcription termination process (By similarity)
AS145_05055	ENOG4105CG2	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity)
AS145_05060	ENOG4108ZAI	phosphatidylglycerophosphatase a
AS145_05065	ENOG4108JQ6	ABC transporter
AS145_05075	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
AS145_05085	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
AS145_05090	ENOG4105CTB	Polyprenyl synthetase
AS145_05095	ENOG41067QG	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
AS145_05100	ENOG4105E14	MotA TolQ exbB proton channel
AS145_05105	ENOG4107XSU	flagellar motor protein motb
AS145_05110	ENOG4108UKH	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
AS145_05120	ENOG4105HBR	Rna-binding protein
AS145_05125	ENOG4105F7M	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit (By similarity)
AS145_05130	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
AS145_05135	ENOG4105EEI	dihydropteroate synthase
AS145_05140	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
AS145_05145	ENOG4105CP7	Triose-phosphate isomerase
AS145_05165	ENOG4105K7D	Required for maturation of 30S ribosomal subunits (By similarity)
AS145_05170	ENOG4105CHV	Transcription elongation factor NusA
AS145_05175	ENOG4107QHU	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
AS145_05180	ENOG4105KG7	Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity)
AS145_05185	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
AS145_05190	ENOG4105K77	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity)
AS145_05195	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
AS145_05205	ENOG4105BZU	Histidine kinase
AS145_05210	ENOG41090EX	DsrE family
AS145_05225	ENOG4105EQ6	Hydrolyzes dipeptides containing N-terminal aspartate residues. May play a role in allowing the cell to use peptide aspartate to spare carbon otherwise required for the synthesis of the aspartate family of amino acids (By similarity)
AS145_05235	ENOG4108NEV	two component transcriptional regulator, LytTR family
AS145_05245	ENOG4108ZXC	Two component transcriptional regulator, luxr family
AS145_05250	ENOG4105BZU	Histidine kinase
AS145_05255	ENOG4105QA4	4Fe-4S Ferredoxin, iron-sulfur binding domain protein
AS145_05260	ENOG4106WHD	Tetrathionate reductase
AS145_05265	ENOG4105DB1	molybdopterin oxidoreductase
AS145_05295	ENOG4107N1Q	ErfK YbiS YcfS YnhG family protein
AS145_05315	ENOG41071R3	Low-potential electron donor to a number of redox enzymes (By similarity)
AS145_05320	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
AS145_05325	ENOG4105M2E	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell (By similarity)
AS145_05330	ENOG4105T95	Thiol disulfide interChange protein
AS145_05335	ENOG4105C2R	Single-stranded-DNA-specific exonuclease (RecJ)
AS145_05340	ENOG4107SWG	transcriptional regulator MERR family
AS145_05355	ENOG4108IUB	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
AS145_05360	ENOG4105MJ9	esterase
AS145_05370	ENOG4105C0G	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity)
AS145_05375	ENOG4108BDP	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity)
AS145_05380	ENOG4108Z43	UPF0250 protein
AS145_05385	ENOG4105DZ1	carboxypeptidase
AS145_05390	ENOG4105K6T	rare lipoprotein A
AS145_05395	ENOG4105CVE	Lytic murein transglycosylase
AS145_05400	ENOG4105CNI	cell division protein FtsW
AS145_05405	ENOG4105CJN	penicillin-binding protein
AS145_05410	ENOG4108UXA	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA (By similarity)
AS145_05415	ENOG4105KEM	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation (By similarity)
AS145_05420	ENOG4108Z1W	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity)
AS145_05435	ENOG4105C8T	Leucyl-tRNA synthetase
AS145_05440	ENOG4107PAI	alpha helical protein
AS145_05445	ENOG4105CE8	Transfers the fatty acyl group on membrane lipoproteins (By similarity)
AS145_05450	ENOG4108JU5	Magnesium and cobalt efflux protein
AS145_05455	ENOG4105KGE	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA (By similarity)
AS145_05460	ENOG4105C9A	Phoh family
AS145_05465	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
AS145_05470	ENOG4105EAK	ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family
AS145_05475	ENOG4106XMA	In vivo, quickly hydrolyzes the ureidoacrylate peracid to avoid toxicity, but can also hydrolyzes ureidoacrylate that is formed spontaneously from ureidoacrylate peracid. One of the products of hydrolysis, carbamate, hydrolyzes spontaneously, thereby releasing one of the pyrimidine rings nitrogen atoms as ammonia and one of its carbons as CO2 (By similarity)
AS145_05485	ENOG4105BZU	Histidine kinase
AS145_05500	ENOG4105EVE	HAD-superfamily hydrolase subfamily IA variant 3
AS145_05510	ENOG4105BZU	Histidine kinase
AS145_05520	ENOG4105C5I	Dehydrogenase
AS145_05530	ENOG4108R5S	membrane
AS145_05535	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
AS145_05545	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
AS145_05555	ENOG4105DHQ	Histidine kinase
AS145_05560	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
AS145_05595	ENOG4105T0Z	Conserved Protein
AS145_05615	ENOG4108VP9	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane (By similarity)
AS145_05620	ENOG4108WJH	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane (By similarity)
AS145_05625	ENOG4105E33	succinate dehydrogenase
AS145_05635	ENOG4105C8Q	Methyl-accepting chemotaxis
AS145_05640	ENOG4108QXE	glycerophosphoryl diester phosphodiesterase
AS145_05645	ENOG4105EGS	Mechanosensitive ion channel
AS145_05655	ENOG4105DR5	peptidase
AS145_05670	ENOG4105EJC	lysr family transcriptional regulator
AS145_05685	ENOG4105C8Q	Methyl-accepting chemotaxis
AS145_05690	ENOG4105C5Q	Transcriptional regulator
AS145_05695	ENOG4108JQC	penicillin-binding protein 1A
AS145_05720	ENOG4105E4G	Type IV pilus
AS145_05725	ENOG4105KHV	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
AS145_05730	ENOG4105D49	3-dehydroquinate synthase
AS145_05740	ENOG4105DFE	Dna adenine methylase
AS145_05745	ENOG4105DJV	ribulose-phosphate 3-epimerase
AS145_05750	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
AS145_05755	ENOG4105C31	Tryptophanyl-tRNA synthetase
AS145_05770	ENOG4105C8Y	Acetylornithine aminotransferase
AS145_05780	ENOG4105C26	Dehydrogenase
AS145_05790	ENOG4107VXZ	Hydrolase
AS145_05800	ENOG4105D95	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin (By similarity)
AS145_05810	ENOG4105CG3	alpha amylase, catalytic region
AS145_05820	ENOG41060QA	UPF0267 protein
AS145_05830	ENOG4108I5U	Uridine phosphorylase
AS145_05835	ENOG4106Z1T	Nicotinamide Mononucleotide Transporter
AS145_05840	ENOG4107QWE	)-transporter
AS145_05885	ENOG4105C3G	gtp-binding protein
AS145_05890	ENOG4108ZPD	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity)
AS145_05895	ENOG4105CGH	5'-nucleotidase
AS145_05900	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
AS145_05915	ENOG4105C1U	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein (By similarity)
AS145_05920	ENOG4105C7E	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) (By similarity)
AS145_05925	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
AS145_05930	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
AS145_05940	ENOG41063JG	Transcriptional regulator
AS145_05945	ENOG4105CXR	Phospho-2-dehydro-3-deoxyoctonate aldolase
AS145_05950	ENOG4105CK2	sodium dicarboxylate symporter
AS145_05955	ENOG4108VKA	Acts as a radical domain for damaged PFL and possibly other radical proteins (By similarity)
AS145_05960	ENOG4105D5S	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine (By similarity)
AS145_05975	ENOG4105CW3	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
AS145_05980	ENOG4105BZG	amino acid carrier protein
AS145_05985	ENOG4105F8C	transglutaminase domain-containing protein
AS145_05995	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
AS145_06000	ENOG41066YJ	Beta-lactamase
AS145_06005	ENOG4105DUX	Transporter
AS145_06010	ENOG4107Y66	Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity)
AS145_06015	ENOG4108UJU	UPF0301 protein
AS145_06025	ENOG4105D7Z	glutathione synthase
AS145_06030	ENOG4105QF0	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity)
AS145_06040	ENOG4105GPY	SprT protein
AS145_06045	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
AS145_06050	ENOG4105CV1	Transketolase (EC 2.2.1.1)
AS145_06060	ENOG4107XTP	(EAL) domain protein
AS145_06070	ENOG4105KME	endoribonuclease L-psp
AS145_06075	ENOG4105TMR	Functions as a holding molecular chaperone (holdase) which stabilizes unfolding intermediates and rapidly releases them in an active form once stress has abated. Plays an important role in protecting cells from severe heat shock and starvation, as well as in acid resistance of stationary-phase cells. It catalyzes the conversion of methylglyoxal (MG) to D-lactate in a single glutathione (GSH)-independent step (By similarity)
AS145_06085	ENOG4105ED7	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling (By similarity)
AS145_06090	ENOG4105DR5	peptidase
AS145_06095	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
AS145_06100	ENOG4107WCA	isomerase
AS145_06110	ENOG4108V1U	phospholipid-binding protein
AS145_06115	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
AS145_06130	ENOG4105C87	Aminotransferase class I and II
AS145_06140	ENOG4105C5Q	Transcriptional regulator
AS145_06145	ENOG4105UBK	short-chain dehydrogenase reductase
AS145_06150	ENOG4105ERU	peptidase
AS145_06155	ENOG4105EY2	Catalyzes the hydrolysis of N(2)-succinylarginine into N(2)-succinylornithine, ammonia and CO(2) (By similarity)
AS145_06160	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
AS145_06175	ENOG4107RHT	methyl-accepting chemotaxis sensory transducer with Pas Pac sensor
AS145_06180	ENOG4105E2D	ec 3.2.1.52
AS145_06185	ENOG4105RD7	BadF BadG BcrA BcrD
AS145_06195	ENOG4108JQ7	(ABC) transporter
AS145_06205	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
AS145_06215	ENOG4108J59	Extracellular solute-binding protein, family 5
AS145_06220	ENOG4105BZU	Histidine kinase
AS145_06240	ENOG4105XIQ	Protein of unknown function (DUF2517)
AS145_06270	ENOG4107SDU	Methyl-accepting chemotaxis
AS145_06280	ENOG4108ESY	Metal dependent phosphohydrolase
AS145_06285	ENOG4105DR8	Membrane
AS145_06290	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
AS145_06295	ENOG4105C6R	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor (By similarity)
AS145_06300	ENOG4108IUZ	ABC transporter
AS145_06305	ENOG4107A5B	Binding-protein-dependent transport systems, inner membrane component
AS145_06315	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
AS145_06320	ENOG4105BZU	Histidine kinase
AS145_06325	ENOG4105HD0	Transcriptional regulator of molybdate metabolism, LysR family
AS145_06330	ENOG4107H9G	Necessary for formate dehydrogenase activity (By similarity)
AS145_06365	ENOG4108IEG	Formate dehydrogenase Alpha subunit
AS145_06365	ENOG4108IEG	Formate dehydrogenase Alpha subunit
AS145_06370	ENOG4105QAX	Iron-sulfur
AS145_06380	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
AS145_06385	ENOG4107R1I	NAD-dependent malic enzyme
AS145_06400	ENOG4105C2W	permease
AS145_06405	ENOG4105HHQ	6-phosphogluconolactonase (EC 3.1.1.31)
AS145_06415	ENOG4105EGS	Mechanosensitive ion channel
AS145_06420	ENOG4105CA9	Pyruvate kinase
AS145_06435	ENOG4105CKD	glutathione-regulated potassium-efflux system protein
AS145_06445	ENOG4105DH7	May be involved in recombination (By similarity)
AS145_06455	ENOG4107RH8	nuclease SbcCD subunit D
AS145_06460	ENOG4105EYH	Exonuclease
AS145_06465	ENOG4105EYH	Exonuclease
AS145_06475	ENOG4105CPW	cytochrome b561
AS145_06485	ENOG4105BZU	Histidine kinase
AS145_06490	ENOG4105C5Y	PTS System
AS145_06500	ENOG4105KZ7	phosphocarrier protein hpr
AS145_06505	ENOG4105C6T	cysteine synthase
AS145_06510	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
AS145_06525	ENOG4108R96	Methyltransferase, YaeB family
AS145_06545	ENOG4108JJ8	(ABC) transporter
AS145_06550	ENOG4108JJ9	ABC, transporter
AS145_06565	ENOG41065U4	response regulator
AS145_06575	ENOG4108YYX	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. Modulates RNA-binding and helicase activities of the degradosome (By similarity)
AS145_06590	ENOG4105VS7	Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue. This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon. When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation (By similarity)
AS145_06595	ENOG4106FVC	RNA methyltransferase
AS145_06605	ENOG4105D5I	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate (By similarity)
AS145_06610	ENOG4105D98	threonine synthase
AS145_06615	ENOG4108VSZ	Inherit from COG: ketosteroid isomerase-like protein
AS145_06630	ENOG4105C5H	ABC transporter
AS145_06640	ENOG4108QW8	Purine nucleoside phosphorylase deoD-type
AS145_06655	ENOG4105BZU	Histidine kinase
AS145_06660	ENOG4105C8E	extradiol ring-cleavage dioxygenase class IIi protein subunit b
AS145_06665	ENOG4108V1T	peptidylprolyl cis-trans isomerase
AS145_06680	ENOG4105CUB	amino acid
AS145_06690	ENOG4105CUB	amino acid
AS145_06695	ENOG4108JPW	Aminotransferase
AS145_06700	ENOG4105C26	Dehydrogenase
AS145_06705	ENOG4107VRI	Transcriptional regulator
AS145_06710	ENOG4105CJP	fad dependent oxidoreductase
AS145_06740	ENOG4105Q26	Siderophore-interacting protein
AS145_06745	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
AS145_06750	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
AS145_06755	ENOG4105DJY	efflux transporter, rnd family, mfp subunit
AS145_06765	ENOG4105E2M	Manganese-dependent inorganic pyrophosphatase
AS145_06775	ENOG4105C4F	May be involved in recombinational repair of damaged DNA (By similarity)
AS145_06780	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
AS145_06785	ENOG4105K90	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
AS145_06790	ENOG4105CFG	Acts as a chaperone (By similarity)
AS145_06795	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
AS145_06805	ENOG4105D7K	pfkb domain protein
AS145_06820	ENOG4105WBN	Transcriptional regulator (LacI family
AS145_06840	ENOG41080HT	Transcriptional regulator, arsr family
AS145_06865	ENOG4105BZU	Histidine kinase
AS145_06870	ENOG4107RMF	Catalyzes both the ATP-dependent activation of exogenously supplied lipoate to lipoyl-AMP and the transfer of the activated lipoyl onto the lipoyl domains of lipoate-dependent enzymes (By similarity)
AS145_06890	ENOG4108IJF	Heavy metal efflux pump, CzcA
AS145_06895	ENOG4105EP1	Efflux transporter rnd family, mfp subunit
AS145_06915	ENOG4105CGK	Exodeoxyribonuclease III
AS145_06930	ENOG4105E5W	Transporter
AS145_06975	ENOG4105E2S	oxidase) subunit II
AS145_06980	ENOG4105BZ9	Cytochrome C oxidase, subunit I
AS145_06985	ENOG4105CCU	oxidase (Subunit III)
AS145_06990	ENOG41090KH	cytochrome o ubiquinol oxidase (subunit iv)
AS145_06995	ENOG4105F1R	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group (By similarity)
AS145_07000	ENOG4107RDB	Major Facilitator
AS145_07010	ENOG4105BZU	Histidine kinase
AS145_07015	ENOG4108SV3	Tmao reductase system periplasmic protein tort
AS145_07025	ENOG4106WF9	DNA-binding transcriptional regulator TorR
AS145_07035	ENOG4108EM1	reductase
AS145_07040	ENOG4109039	Involved in the biogenesis of TorA. Acts on TorA before the insertion of the molybdenum cofactor and, as a result, probably favors a conformation of the apoenzyme that is competent for acquiring the cofactor (By similarity)
AS145_07080	ENOG4108YGG	dna repair protein
AS145_07120	ENOG4105F52	Transcriptional regulator
AS145_07135	ENOG4105C5B	carbamate kinase
AS145_07140	ENOG4107REC	cytoplasmic protein
AS145_07145	ENOG4107R1Q	Membrane protein FdrA
AS145_07150	ENOG4106XMA	In vivo, quickly hydrolyzes the ureidoacrylate peracid to avoid toxicity, but can also hydrolyzes ureidoacrylate that is formed spontaneously from ureidoacrylate peracid. One of the products of hydrolysis, carbamate, hydrolyzes spontaneously, thereby releasing one of the pyrimidine rings nitrogen atoms as ammonia and one of its carbons as CO2 (By similarity)
AS145_07165	ENOG410679B	prophage CP4-57 regulatory protein alpA
AS145_07185	ENOG4105D9N	nucleoside
AS145_07215	ENOG4105F6H	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate (By similarity)
AS145_07220	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
AS145_07225	ENOG4105DK0	Indole-3-glycerol phosphate synthase
AS145_07230	ENOG4108I0Q	anthranilate phosphoribosyltransferase
AS145_07235	ENOG4108EFP	Anthranilate synthase component II
AS145_07240	ENOG4105CRQ	synthase (Component I)
AS145_07245	ENOG4105DB7	PHP domain protein
AS145_07250	ENOG4107RTD	sua5 ycio yrdc ywlc family protein
AS145_07260	ENOG4105K8I	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves (By similarity)
AS145_07265	ENOG4105FE9	pseudouridine synthase
AS145_07270	ENOG4105C29	acyl-CoA thioesterase
AS145_07285	ENOG4108IG5	Transcriptional regulator
AS145_07290	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
AS145_07295	ENOG4105BZS	acriflavin resistance protein
AS145_07300	ENOG4105C1B	dTDP-glucose 4-6-dehydratase
AS145_07315	ENOG4105EGZ	biosynthesis protein
AS145_07325	ENOG4105C0K	Gdp-mannose 4,6-dehydratase
AS145_07330	ENOG4105C30	Nad-dependent epimerase dehydratase
AS145_07335	ENOG4105CJT	Mannose-1-phosphate guanylyltransferase
AS145_07345	ENOG4105ESV	Glycosyl transferase, family 4
AS145_07350	ENOG4105DBZ	Dtdp-4-dehydrorhamnose reductase
AS145_07355	ENOG4108I19	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis (By similarity)
AS145_07365	ENOG4108QY5	Ferric enterobactin transport protein
AS145_07385	ENOG4105E3R	(LipO)protein
AS145_07395	ENOG4108YXG	UPF0502 protein
AS145_07405	ENOG4105KR1	Trans-acting protein required for termination of DNA replication. Binds to DNA replication terminator sequences (terA to terF) to prevent the passage of replication forks. The termination efficiency will be affected by the affinity of this protein for the terminator sequence (By similarity)
AS145_07420	ENOG4107RUY	(E1 component), alpha subunit
AS145_07425	ENOG4105CPP	Dehydrogenase, E1 component
AS145_07430	ENOG4107QSN	dihydrolipoamide acetyltransferase
AS145_07435	ENOG4105VEQ	Cold shock protein
AS145_07465	ENOG4108594	Permease of the drug metabolite transporter
AS145_07470	ENOG4105N2W	Transcriptional regulator
AS145_07475	ENOG4105C6N	Formate acetyltransferase
AS145_07480	ENOG4105F1A	Pyruvate formate-lyase
AS145_07485	ENOG4107T9Z	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
AS145_07495	ENOG4105CPI	Metal Dependent Phosphohydrolase
AS145_07500	ENOG4105I08	Pseudouridine synthase
AS145_07510	ENOG4107QSI	ABC, transporter
AS145_07515	ENOG4108RE9	Phosphodiesterase
AS145_07530	ENOG4107ESN	Flagella basal body P-ring formation protein flgA
AS145_07535	ENOG4107R88	Chemotaxis protein (CheV)
AS145_07540	ENOG4105BZU	Histidine kinase
AS145_07545	ENOG4105K88	Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body (By similarity)
AS145_07550	ENOG4108ZC9	flagellar basal-body rod protein flgc
AS145_07560	ENOG4105BZE	flagellar hook protein, FlgE
AS145_07565	ENOG4108KPB	Flagellar basal-body rod protein FlgF
AS145_07570	ENOG4105CGA	flagellar basal-body rod protein FlgG
AS145_07575	ENOG4107W7W	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity)
AS145_07580	ENOG4105D92	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity)
AS145_07585	ENOG4108ZW7	flagellar rod assembly protein muramidase flgj
AS145_07590	ENOG4105E1Q	flagellar hook-associated protein
AS145_07595	ENOG4105DTJ	flagellar hook-associated protein
AS145_07600	ENOG4105CJW	magnesium transporter
AS145_07605	ENOG4105C9X	ppx gppa phosphatase
AS145_07610	ENOG4105CUU	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) (By similarity)
AS145_07615	ENOG4105RH4	Glycine cleavage system transcriptional repressor
AS145_07625	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
AS145_07630	ENOG4105BZU	Histidine kinase
AS145_07635	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
AS145_07640	ENOG4107QNR	UPF0135 protein
AS145_07645	ENOG4108V3E	phosphoribosylglycinamide formyltransferase
AS145_07650	ENOG4105CXB	phosphoribosylaminoimidazole synthetase
AS145_07655	ENOG4105CZ5	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate (By similarity)
AS145_07670	ENOG4108I9X	Isocitrate lyase
AS145_07675	ENOG4107QP3	malate synthase g
AS145_07685	ENOG4108Z6B	deaminase
AS145_07690	ENOG4105C8U	phosphate abc transporter
AS145_07695	ENOG4105E2Z	phosphate ABC transporter (Permease
AS145_07700	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
AS145_07710	ENOG4105C37	(CBS) domain
AS145_07720	ENOG4105C3R	Methionine synthase
AS145_07725	ENOG4105D5Q	Arginine ornithine antiporter
AS145_07740	ENOG4105CDA	abc transporter atp-binding protein
AS145_07745	ENOG4105E5Q	amino acid AbC transporter
AS145_07750	ENOG4106TNF	Periplasmic binding protein
AS145_07755	ENOG4105BZU	Histidine kinase
AS145_07760	ENOG4105CXY	transporter
AS145_07765	ENOG4105BZU	Histidine kinase
AS145_07770	ENOG4108KX4	response regulator
AS145_07775	ENOG4105NXH	GreA GreB family elongation factor
AS145_07805	ENOG4105C9W	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity (By similarity)
AS145_07810	ENOG4108ISG	Major Facilitator
AS145_07815	ENOG4105DGU	Histone deacetylase
AS145_07825	ENOG4105DVT	helicase
AS145_07830	ENOG4105QMY	Porin Gram-negative type
AS145_07840	ENOG4105CGF	Aromatic amino acid aminotransferase
AS145_07845	ENOG4105D7A	ATP-binding protein
AS145_07910	ENOG4105CSW	GntR family transcriptional regulator
AS145_07915	ENOG4105UVJ	5-dehydro-4-deoxyglucarate dehydratase
AS145_07925	ENOG4108YXU	transcriptional regulator AsnC family
AS145_08000	ENOG4105CHD	Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) (By similarity)
AS145_08005	ENOG4105W49	UPF0434 protein
AS145_08010	ENOG4105CET	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria (By similarity)
AS145_08015	ENOG4105WH1	Two component transcriptional regulator luxr family
AS145_08020	ENOG4105CII	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity)
AS145_08105	ENOG4105KSC	Transcriptional regulator, TraR DksA family
AS145_08155	ENOG4105ED4	portal protein
AS145_08240	ENOG4105RDA	repressor
AS145_08250	ENOG4108IYS	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
AS145_08280	ENOG4105E5H	Transposase
AS145_08290	ENOG4105C26	Dehydrogenase
AS145_08300	ENOG4108HRG	Involved in the cleavage of the C1-C2 bond of 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy- glucuronate (5DG) (By similarity)
AS145_08310	ENOG4105E9V	Periplasmic binding protein LacI transcriptional regulator
AS145_08320	ENOG4105CNN	ABC, transporter
AS145_08330	ENOG4105D7K	pfkb domain protein
AS145_08340	ENOG4105DH8	myo-inositol catabolism
AS145_08345	ENOG4105F2I	Transposase
AS145_08350	ENOG4108ZQS	transposase
AS145_08355	ENOG4108MVM	Transposase
AS145_08420	ENOG4105JJ8	Cytochrome c nitrite reductase, pentaheme subunit
AS145_08425	ENOG4105D3S	4Fe-4S Ferredoxin, iron-sulfur binding domain protein
AS145_08430	ENOG4105DVI	reductase, NrfD
AS145_08435	ENOG4105F10	Catalyzes the hydrolysis of the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1- phosphate (lipid X) and UMP (By similarity)
AS145_08445	ENOG4108R5K	PPIases accelerate the folding of proteins (By similarity)
AS145_08465	ENOG410620I	Diguanylate cyclase
AS145_08500	ENOG4108ZJT	translation initiation factor, Sui1
AS145_08525	ENOG4107QQ4	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans (By similarity)
AS145_08530	ENOG4105CZX	twitching motility protein
AS145_08540	ENOG4105BZU	Histidine kinase
AS145_08545	ENOG4108ESU	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Involved in the translocation of the substrate across the membrane (By similarity)
AS145_08550	ENOG41080WI	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system (By similarity)
AS145_08560	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
AS145_08565	ENOG41080IJ	Diacylglycerol kinase
AS145_08570	ENOG4108JQ1	Dehydrogenase
AS145_08575	ENOG4105E66	phosphoriboisomerase A
AS145_08580	ENOG4105E66	phosphoriboisomerase A
AS145_08585	ENOG4105MK2	5-formyltetrahydrofolate cyclo-ligase
AS145_08595	ENOG4105DUK	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity)
AS145_08600	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
AS145_08605	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
AS145_08610	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
AS145_08615	ENOG4107QS8	(LipO)protein
AS145_08620	ENOG4108MIB	
AS145_08640	ENOG4108MK9	spermidine N(1)-acetyltransferase
AS145_08645	ENOG4105C1J	atp-dependent rna helicase
AS145_08670	ENOG4108Z4X	TRANSCRIPTIONal
AS145_08685	ENOG4105EAB	amino acid AbC transporter
AS145_08690	ENOG4105DRP	amino acid AbC transporter
AS145_08695	ENOG4105CDA	abc transporter atp-binding protein
AS145_08700	ENOG4105BZ8	glutamate synthase
AS145_08705	ENOG4105CBC	glutamate synthase
AS145_08710	ENOG4105N5T	Radical SAM Protein
AS145_08720	ENOG4105C42	Type I secretion membrane fusion protein (HlyD
AS145_08765	ENOG4105C85	amino acid
AS145_08775	ENOG4105CF9	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation (By similarity)
AS145_08780	ENOG4108HRN	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate (By similarity)
AS145_08825	ENOG4105D01	(LipO)protein
AS145_08830	ENOG4105EYK	Phosphatidylglycerophosphatase B
AS145_08835	ENOG4105CJ0	Catalyzes the oxidation of erythronate-4-phosphate to 3- hydroxy-2-oxo-4-phosphonooxybutanoate (By similarity)
AS145_08840	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
AS145_08850	ENOG4105DI7	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity)
AS145_08855	ENOG4107QTG	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA (By similarity)
AS145_08860	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
AS145_08865	ENOG4108S3P	Sporulation domain protein
AS145_08870	ENOG4108Z0T	Part of a sulfur-relay system (By similarity)
AS145_08875	ENOG4105EM2	membrane
AS145_08880	ENOG4108MN8	Membrane
AS145_08900	ENOG4105DIJ	Phosphoethanolamine transferase
AS145_08910	ENOG4105FF5	Membrane
AS145_08920	ENOG4107RHT	methyl-accepting chemotaxis sensory transducer with Pas Pac sensor
AS145_08925	ENOG4105BZU	Histidine kinase
AS145_08930	ENOG4108W1A	pseudouridine synthase
AS145_08940	ENOG4105E6K	4-Hydroxyphenylpyruvate dioxygenase
AS145_08945	ENOG4105F1J	Homogentisate 1,2-dioxygenase
AS145_08955	ENOG4108RXX	maleylacetoacetate isomerase
AS145_08960	ENOG4108TGY	Glutathione S-transferase
AS145_08970	ENOG4105CAQ	asparagine synthetase
AS145_08980	ENOG4105CKD	glutathione-regulated potassium-efflux system protein
AS145_08985	ENOG4105D4U	had-superfamily hydrolase, subfamily iia
AS145_08990	ENOG4105EKD	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism (By similarity)
AS145_08995	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
AS145_09000	ENOG4105EE5	Membrane protein terC
AS145_09010	ENOG4105CQB	FAD linked oxidase domain protein
AS145_09020	ENOG4105KA0	thioesterase Superfamily protein
AS145_09030	ENOG4105D3Y	Na H antiporter
AS145_09035	ENOG4105DH5	Responsible for the end-turnover of tRNA specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis (By similarity)
AS145_09045	ENOG4105EIY	sodium-type flagellar protein motY
AS145_09050	ENOG4108UYE	Lactoylglutathione lyase
AS145_09055	ENOG4105CSM	endonuclease III
AS145_09060	ENOG4105DZB	Electron transport complex
AS145_09070	ENOG4105D6A	Electron transport complex
AS145_09080	ENOG4108R3D	Electron transport complex
AS145_09085	ENOG4105DGN	Electron transport complex
AS145_09090	ENOG4108PCN	EamA-like transporter family
AS145_09100	ENOG4107SDU	Methyl-accepting chemotaxis
AS145_09105	ENOG4105RKW	reductase (By
AS145_09110	ENOG4105CSX	c4-dicarboxylate anaerobic carrier
AS145_09115	ENOG4105CHM	Aminotransferase
AS145_09125	ENOG41090BQ	Glutaredoxin
AS145_09130	ENOG4106HRJ	d-alanyl-d-alanine carboxypeptidase
AS145_09135	ENOG4105CFI	type iii restriction protein res subunit
AS145_09140	ENOG4105EFX	secretion protein, HlyD family
AS145_09145	ENOG4105KK7	inner membrane protein YiaW
AS145_09155	ENOG4108NEV	two component transcriptional regulator, LytTR family
AS145_09160	ENOG4108HRK	Histidine kinase
AS145_09165	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
AS145_09170	ENOG4108EKI	Dehydrogenase
AS145_09180	ENOG4105EZI	multiple antibiotic resistance (MarC)-related protein
AS145_09185	ENOG4107QSI	ABC, transporter
AS145_09190	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
AS145_09195	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
AS145_09200	ENOG4105C3U	ABC transporter
AS145_09210	ENOG4108JQ7	(ABC) transporter
AS145_09215	ENOG4105DU1	integral membrane protein, terc
AS145_09220	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
AS145_09230	ENOG4105CK2	sodium dicarboxylate symporter
AS145_09245	ENOG4105CD3	dihydroorotase
AS145_09255	ENOG4108NVR	Methyl-accepting chemotaxis
AS145_09260	ENOG4105K59	histidine triad (HIT) protein
AS145_09295	ENOG4107QN8	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
AS145_09300	ENOG4107RAB	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
AS145_09310	ENOG4105CKW	Inner membrane protein yedI
AS145_09315	ENOG4105DPN	Oligoendopeptidase f
AS145_09320	ENOG4105DPN	Oligoendopeptidase f
AS145_09325	ENOG4105C2W	permease
AS145_09335	ENOG4105CEP	NADH dehydrogenase
AS145_09355	ENOG4105K8R	UPF0145 protein
AS145_09365	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
AS145_09370	ENOG410810Y	Sulfite reductase
AS145_09375	ENOG4107SHJ	sulfite reductase subunit b
AS145_09380	ENOG4105D5B	Sulfite reductase, subunit A
AS145_09385	ENOG4108NRW	Phospholipase, patatin family
AS145_09390	ENOG4105EBE	Peptidase U61, LD-carboxypeptidase A
AS145_09395	ENOG4107T7U	Sulfatase
AS145_09405	ENOG4105CFH	Aspartokinase
AS145_09410	ENOG4107QZM	n-acetylglutamate synthase
AS145_09415	ENOG4107QXP	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
AS145_09440	ENOG4105F2Z	3-oxoadipate enol-lactonase
AS145_09455	ENOG4105CR8	Transcriptional regulator
AS145_09460	ENOG4105DAA	L-lactate
AS145_09470	ENOG4107QR9	Iron-sulfur cluster binding protein
AS145_09475	ENOG4108ZZK	Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source (By similarity)
AS145_09495	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
AS145_09505	ENOG4105C2C	drug resistance transporter, Bcr CflA
AS145_09555	ENOG4105CHH	sulfate transporter
AS145_09600	ENOG4108ZQS	transposase
AS145_09620	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
AS145_09625	ENOG4105C8Q	Methyl-accepting chemotaxis
AS145_09630	ENOG4105BZU	Histidine kinase
AS145_09635	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
AS145_09640	ENOG4105BZU	Histidine kinase
AS145_09645	ENOG4108V3W	Chemotaxis protein, CheW
AS145_09650	ENOG4105C8Q	Methyl-accepting chemotaxis
AS145_09655	ENOG4105CBS	Chea signal transduction histidine kinase
AS145_09665	ENOG4108VYJ	response regulator receiver protein
AS145_09670	ENOG4105E3S	small subunit
AS145_09675	ENOG4105QA4	4Fe-4S Ferredoxin, iron-sulfur binding domain protein
AS145_09680	ENOG4105CJ5	hydrogenase 2 b cytochrome subunit
AS145_09685	ENOG4105DPX	Hydrogenase, large subunit
AS145_09690	ENOG4108USZ	hydrogenase
AS145_09695	ENOG4108WGS	hydrogenase 2-specific chaperone
AS145_09700	ENOG4107RNA	Nickel ABC transporter, periplasmic nickel-binding protein
AS145_09705	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
AS145_09710	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
AS145_09715	ENOG4105C3U	ABC transporter
AS145_09720	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
AS145_09725	ENOG4107RSS	Hydrogenase accessory protein HypB
AS145_09730	ENOG4105WMM	Probably plays a role in a hydrogenase nickel cofactor insertion step (By similarity)
AS145_09735	ENOG4105C45	hydrogenase expression formation protein (HypE)
AS145_09740	ENOG4105CQS	hydrogenase expression formation protein HypD
AS145_09745	ENOG4105WRB	Hydrogenase assembly chaperone hypC hupF
AS145_09755	ENOG4105EM7	Selenocysteine-specific translation elongation factor
AS145_09760	ENOG4105C1Y	Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis (By similarity)
AS145_09765	ENOG4108MG9	hydrogenase 3 maturation protease
AS145_09770	ENOG4105I6X	formate hydrogenlyase maturation
AS145_09775	ENOG4105C47	NADH ubiquinone oxidoreductase 20 kda subunit
AS145_09785	ENOG4105CQV	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
AS145_09790	ENOG4107TDF	Formate hydrogenlyase subunit 4
AS145_09795	ENOG4108JPZ	Monovalent cation H antiporter subunit D
AS145_09800	ENOG4108MFN	small subunit of hydrogenase-3, iron-sulfur protein (part of formate hydrogenlyase (FHL) complex)
AS145_09805	ENOG4105DFH	Transport of potassium into the cell (By similarity)
AS145_09810	ENOG4108RC0	Electron transport protein
AS145_09815	ENOG4107QIW	Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity)
AS145_09820	ENOG4107QIW	Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity)
AS145_09830	ENOG4108JUA	Transcriptional regulator
AS145_09835	ENOG4107H9G	Necessary for formate dehydrogenase activity (By similarity)
AS145_09840	ENOG4105F3K	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity)
AS145_09845	ENOG4105CJX	Molecular chaperone. Has ATPase activity (By similarity)
AS145_09850	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
AS145_09855	ENOG4105CFX	Catalyzes the ferrous insertion into protoporphyrin IX (By similarity)
AS145_09865	ENOG4107RE1	Inosine-guanosine kinase
AS145_09885	ENOG4107QQ4	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans (By similarity)
AS145_09895	ENOG4105F3T	(LipO)protein
AS145_09905	ENOG4108IQC	2,3-dihydroxybenzoate-AMP ligase
AS145_09910	ENOG4105WQI	isochorismatase
AS145_09915	ENOG4105CEY	Amp-dependent synthetase and ligase
AS145_09920	ENOG4105X17	23-dihydro-2,3-dihydroxybenzoate dehydrogenase
AS145_09930	ENOG4105CEY	Amp-dependent synthetase and ligase
AS145_09935	ENOG4108MES	Periplasmic binding protein
AS145_09940	ENOG4108TSE	Transferase
AS145_09945	ENOG4105E0A	ABC, transporter
AS145_09950	ENOG4105TVJ	transport system, permease
AS145_09955	ENOG4105DQ5	transport system permease protein
AS145_09960	ENOG4105D05	Receptor
AS145_09975	ENOG4105QZU	Inner membrane protein YfeZ
AS145_09980	ENOG4107QUT	magnesium and cobalt transport protein CorA
AS145_09985	ENOG4105DWH	electron transfer flavoprotein-ubiquinone oxidoreductase
AS145_09990	ENOG4105BZJ	Electron transfer flavoprotein
AS145_09995	ENOG4105C10	Electron transfer flavoprotein
AS145_10000	ENOG4107QM1	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine (By similarity)
AS145_10005	ENOG4105CMY	5-enolpyruvylshikimate-3-phosphate synthase
AS145_10010	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
AS145_10015	ENOG4108NVR	Methyl-accepting chemotaxis
AS145_10020	ENOG4105D4P	Coproporphyrinogen iii oxidase
AS145_10025	ENOG4105DVS	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
AS145_10050	ENOG4105DFH	Transport of potassium into the cell (By similarity)
AS145_10055	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
AS145_10060	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
AS145_10065	ENOG4105DFP	Integrase
AS145_10105	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
AS145_10120	ENOG4105FQ6	thiopurine methyltransferase
AS145_10125	ENOG4107VK2	coenzyme PQQ biosynthesis protein PqqF
AS145_10130	ENOG4108BY2	phosphohistidine phosphatase
AS145_10140	ENOG4108IPJ	Membrane
AS145_10145	ENOG4108J59	Extracellular solute-binding protein, family 5
AS145_10150	ENOG4105CZI	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
AS145_10155	ENOG4108JA2	transcriptioN-repair coupling factor
AS145_10165	ENOG4105D60	lipoprotein releasing system transmembrane protein
AS145_10170	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
AS145_10175	ENOG4105D60	lipoprotein releasing system transmembrane protein
AS145_10190	ENOG4105DEA	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation
AS145_10195	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
AS145_10200	ENOG4105CHN	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
AS145_10205	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
AS145_10215	ENOG4105EIN	peptidylprolyl cis-trans isomerase
AS145_10220	ENOG4105C5H	ABC transporter
AS145_10225	ENOG4107QN1	sodium solute
AS145_10230	ENOG41062QD	Membrane
AS145_10245	ENOG41060WC	Enoyl-CoA hydratase
AS145_10280	ENOG4105BZG	amino acid carrier protein
AS145_10295	ENOG4106HK8	GPR1 FUN34 yaaH family protein
AS145_10330	ENOG4107QX3	carboxylase
AS145_10335	ENOG4105C1G	acyl-Coa dehydrogenase
AS145_10340	ENOG4105C26	Dehydrogenase
AS145_10345	ENOG4105C1G	acyl-Coa dehydrogenase
AS145_10350	ENOG4105E39	Enoyl-CoA hydratase
AS145_10355	ENOG4105E39	Enoyl-CoA hydratase
AS145_10360	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
AS145_10365	ENOG4105CHR	reductase
AS145_10370	ENOG4105D5Q	Arginine ornithine antiporter
AS145_10375	ENOG4105HF0	Membrane
AS145_10395	ENOG4105BZU	Histidine kinase
AS145_10400	ENOG4105W5Q	DNA repair protein (RadC
AS145_10420	ENOG4105EQ2	LysR family Transcriptional regulator
AS145_10425	ENOG4105ENX	hydrolase
AS145_10430	ENOG4105DRY	peptidase s9 prolyl oligopeptidase active site domain protein
AS145_10440	ENOG4105HEI	LysR family (Transcriptional regulator
AS145_10445	ENOG4105CPC	Aldo Keto reductase
AS145_10460	ENOG4105BZU	Histidine kinase
AS145_10465	ENOG4108KB2	LysR family Transcriptional regulator
AS145_10470	ENOG4105CS2	ec 3.2.1.21
AS145_10475	ENOG4105BZU	Histidine kinase
AS145_10485	ENOG4105DHT	Metal Dependent Phosphohydrolase
AS145_10490	ENOG4105CHR	reductase
AS145_10495	ENOG4105CBN	LysR family transcriptional regulator
AS145_10500	ENOG4105EFU	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin (By similarity)
AS145_10510	ENOG4105DUM	transcriptional regulator, lysR family
AS145_10520	ENOG4105NWR	lipid A biosynthesis (Kdo)2-(Lauroyl)-lipid IVA acyltransferase
AS145_10525	ENOG4105NWR	lipid A biosynthesis (Kdo)2-(Lauroyl)-lipid IVA acyltransferase
AS145_10550	ENOG4105CQ2	DNA polymerase
AS145_10580	ENOG4107QI1	Mate efflux family protein
AS145_10585	ENOG4105W1I	UPF0253 protein
AS145_10590	ENOG4108R6K	riboflavin synthase, subunit alpha
AS145_10600	ENOG4107UW8	HAD-superfamily hydrolase subfamily IA variant 3
AS145_10605	ENOG4108HH9	Catalyzes two reactions the first one is the production of beta-formyl glycinamide ribonucleotide (GAR) from formate, ATP and beta GAR
AS145_10610	ENOG4108SXK	Transporter Drug Metabolite Exporter family
AS145_10615	ENOG4108V3G	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity)
AS145_10650	ENOG4105XW2	UPF0263 protein
AS145_10655	ENOG4108VKV	Monofunctional biosynthetic peptidoglycan transglycosylase
AS145_10665	ENOG4105VJP	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell (By similarity)
AS145_10670	ENOG4107QMS	site-determining protein
AS145_10675	ENOG4105K7U	Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization (By similarity)
AS145_10680	ENOG4105VNG	YcgL domain-containing protein
AS145_10685	ENOG4105CVE	Lytic murein transglycosylase
AS145_10690	ENOG4105EJQ	L-serine dehydratase
AS145_10695	ENOG4105EJQ	L-serine dehydratase
AS145_10700	ENOG4105NBK	UPF0345 protein
AS145_10705	ENOG4105CK2	sodium dicarboxylate symporter
AS145_10715	ENOG4105CHU	acetyl-coa acetyltransferase
AS145_10720	ENOG4105D58	Diguanylate phosphodiesterase
AS145_10730	ENOG4105CKF	membrane protein involved in aromatic hydrocarbon degradation
AS145_10740	ENOG4105EMN	RNA polymerase sigma factor
AS145_10770	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
AS145_10775	ENOG4105CHU	acetyl-coa acetyltransferase
AS145_10780	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
AS145_10785	ENOG4108VWS	Yaeq family
AS145_10805	ENOG4108TVE	i protein
AS145_10810	ENOG4108JUB	Transcriptional regulator
AS145_10815	ENOG4105IW6	Carbamoyltransferase
AS145_10820	ENOG4107RCH	Diaminopropionate ammonia-lyase
AS145_10825	ENOG4107S4Y	M20 DapE family protein YgeY
AS145_10835	ENOG4105C5B	carbamate kinase
AS145_10840	ENOG4108Q5Y	Membrane
AS145_10845	ENOG4107P0T	Selenium-dependent molybdenum hydroxylase system protein, YqeB family
AS145_10850	ENOG4105MJ6	selenium-dependent hydroxylase accessory protein YqeC
AS145_10860	ENOG4105BZ8	glutamate synthase
AS145_10865	ENOG4107UUR	Chlorohydrolase aminohydrolase
AS145_10870	ENOG410873Y	FAD binding domain in molybdopterin dehydrogenase
AS145_10875	ENOG4105C7W	Xanthine dehydrogenase
AS145_10880	ENOG4105C2W	permease
AS145_10885	ENOG4107QUY	Guanine deaminase
AS145_10890	ENOG4105C7N	Xanthine uracil vitamin C permease
AS145_10895	ENOG4105C7W	Xanthine dehydrogenase
AS145_10900	ENOG4108HR6	Dehydrogenase
AS145_10905	ENOG4108UTP	(2Fe-2S)-binding domain protein
AS145_10915	ENOG4107MBR	17 kDa surface antigen
AS145_10925	ENOG4105CSX	c4-dicarboxylate anaerobic carrier
AS145_10930	ENOG4105CEY	Amp-dependent synthetase and ligase
AS145_10935	ENOG4105K8F	Phosphoribosyl-amp cyclohydrolase
AS145_10940	ENOG4105C0S	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity)
AS145_10945	ENOG4105BZU	Histidine kinase
AS145_10955	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
AS145_10960	ENOG4105CJV	Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase
AS145_10965	ENOG4108UJE	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity)
AS145_10975	ENOG4105CIH	Imidazole acetol-phosphate transaminase
AS145_10980	ENOG4105CEK	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity)
AS145_10985	ENOG4105E21	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity)
AS145_10995	ENOG4105DVT	helicase
AS145_11000	ENOG41072GX	Peptidase M22 Glycoprotease
AS145_11010	ENOG410626R	Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity)
AS145_11015	ENOG4105CEY	Amp-dependent synthetase and ligase
AS145_11020	ENOG4105ZIE	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides (By similarity)
AS145_11025	ENOG4106PMH	Extracellular solute-binding protein family 3
AS145_11130	ENOG4107TII	Recombinase
AS145_11140	ENOG4105FBT	Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs (By similarity)
AS145_11145	ENOG4105WD1	Membrane
AS145_11150	ENOG4109003	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity)
AS145_11155	ENOG4107QMP	dna polymerase iii subunits gamma and tau
AS145_11160	ENOG4105KDX	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection (By similarity)
AS145_11165	ENOG4107R08	Integrase
AS145_11195	ENOG41076J9	exonuclease VIII
AS145_11285	ENOG4105CH6	catalase
AS145_11310	ENOG4108ZUE	Phage regulatory protein rha
AS145_11315	ENOG4105NY2	NinB protein
AS145_11335	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
AS145_11340	ENOG4105KT5	UmuD protein
AS145_11515	ENOG4105CQ7	ATP-dependent helicase
AS145_11530	ENOG4105BZU	Histidine kinase
AS145_11535	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
AS145_11540	ENOG4105C5X	domain protein
AS145_11545	ENOG4105CR7	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA (By similarity)
AS145_11550	ENOG4105D4F	Synthesizes selenophosphate from selenide and ATP (By similarity)
AS145_11560	ENOG4105FAT	Acyl-transferase
AS145_11570	ENOG4105DR4	Methyltransferase
AS145_11575	ENOG4108N3W	hemolysin secretion protein
AS145_11580	ENOG4105VSY	K01512 acylphosphatase EC 3.6.1.7
AS145_11585	ENOG4108K3A	Glutathione S-transferase
AS145_11590	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
AS145_11595	ENOG4105D1F	ATP-binding protein
AS145_11600	ENOG4105DBI	uridine monophosphokinase
AS145_11605	ENOG4105DHP	deoxycytidine triphosphate deaminase
AS145_11610	ENOG4105CJ3	phosphate transporter
AS145_11615	ENOG4105C03	ribonuclease
AS145_11620	ENOG4105EI2	Pseudouridine synthase
AS145_11630	ENOG4108UHJ	MAF-like protein
AS145_11635	ENOG4105CNH	Multidrug resistance protein MdtL
AS145_11650	ENOG4105FCQ	metal-binding, possibly nucleic acid-binding protein
AS145_11655	ENOG4105VGS	50s ribosomal protein l32
AS145_11660	ENOG4105C6B	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA (By similarity)
AS145_11665	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
AS145_11670	ENOG4105CJF	Malonyl coA-acyl carrier protein transacylase
AS145_11675	ENOG4105CHR	reductase
AS145_11680	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
AS145_11685	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
AS145_11690	ENOG4105YAZ	4-amino-4-deoxychorismate lyase
AS145_11695	ENOG4105HHA	aminodeoxychorismate lyase
AS145_11700	ENOG4108ZMD	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity)
AS145_11705	ENOG4107QRG	dna polymerase iii
AS145_11710	ENOG4105F8V	Hydrolase, tatD family
AS145_11725	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
AS145_11730	ENOG4105DY2	Paraquat-inducible protein b
AS145_11735	ENOG4105F1S	paraquat-inducible protein a
AS145_11745	ENOG4105CR4	methylisocitrate lyase
AS145_11750	ENOG4105BZN	citrate synthase
AS145_11755	ENOG4105DXD	2-methylcitrate dehydratase
AS145_11795	ENOG4105PDP	Short chain dehydrogenase
AS145_11805	ENOG4105X2V	dna damage-inducible protein
AS145_11815	ENOG4105DAN	ATP-dependent protease
AS145_11820	ENOG4108RKI	Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl- ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)- decenoyl-ACP. Can catalyze the dehydratase reaction for beta- hydroxyacyl-ACPs with saturated chain lengths up to 16 0, being most active on intermediate chain length (By similarity)
AS145_11830	ENOG4105C5H	ABC transporter
AS145_11840	ENOG4105C4H	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA (By similarity)
AS145_11845	ENOG4108T7E	Contributes to the efficiency of the cell division process by stabilizing the polymeric form of the cell division protein FtsZ. Acts by promoting interactions between FtsZ protofilaments and suppressing the GTPase activity of FtsZ (By similarity)
AS145_11850	ENOG4107QYT	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor (By similarity)
AS145_11855	ENOG4105C7I	Dehydrogenase
AS145_11865	ENOG4105CD8	aminopeptidase N
AS145_11870	ENOG4105CN1	protease
AS145_11875	ENOG41073DY	may be a structural element that influences the osmotic activation of ProP at a post-translational level (By similarity)
AS145_11880	ENOG4108ZGC	gaf domain protein
AS145_11890	ENOG4105EUH	cytochrome C oxidase, cbb3-type, subunit i
AS145_11905	ENOG4105D6P	C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex (By similarity)
AS145_11930	ENOG4105DS0	Transcriptional regulator, Crp Fnr family
AS145_11935	ENOG4105Q9Y	Universal stress protein
AS145_11940	ENOG4105CB3	Required for the thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32) (By similarity)
AS145_11955	ENOG4108RXX	maleylacetoacetate isomerase
AS145_11960	ENOG4105MRB	Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose (By similarity)
AS145_11965	ENOG4105C2J	ABC transporter
AS145_11970	ENOG4105CNN	ABC, transporter
AS145_11975	ENOG4105E9V	Periplasmic binding protein LacI transcriptional regulator
AS145_11980	ENOG4108RVA	ribokinase
AS145_11985	ENOG4105ETE	Transcriptional regulator (LacI family
AS145_12000	ENOG4105NDF	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity)
AS145_12015	ENOG4105BZU	Histidine kinase
AS145_12020	ENOG4108ZUF	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
AS145_12025	ENOG4105C6A	phenylalanyl-tRNA synthetase (beta subunit)
AS145_12030	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
AS145_12035	ENOG4108YZX	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity)
AS145_12040	ENOG41083UC	50s ribosomal protein L35
AS145_12045	ENOG4108UUX	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity)
AS145_12050	ENOG4105C22	threonyL-tRNA synthetase
AS145_12065	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
AS145_12070	ENOG4108HWB	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
AS145_12075	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
AS145_12080	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
AS145_12085	ENOG4105E05	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
AS145_12090	ENOG4105XPH	Ferredoxin
AS145_12095	ENOG4105CA3	membrane-bound lytic murein transglycosylase
AS145_12100	ENOG4105XZD	Fe-S protein
AS145_12105	ENOG4107SZR	mannose-6-phosphate isomerase
AS145_12110	ENOG4105F3R	pts system mannose fructose sorbose family iid
AS145_12115	ENOG4105ETZ	PTS System
AS145_12120	ENOG4108EQA	pts system
AS145_12135	ENOG4107P2S	Transcriptional regulator
AS145_12140	ENOG4108Y83	glucose-6-phosphate isomerase
AS145_12145	ENOG4105DM4	PTS System
AS145_12150	ENOG4105DE4	1-phosphofructokinase
AS145_12155	ENOG4105DTZ	bifunctional PTS system fructose-specific transporter subunit IIA HPr protein
AS145_12160	ENOG4107B7Y	DNA-binding transcriptional regulator FruR
AS145_12165	ENOG4105E0U	tyrosine-specific transport protein
AS145_12180	ENOG4105C1J	atp-dependent rna helicase
AS145_12190	ENOG4105D10	5-enolpyruvylshikimate-3-phosphate phospholyase
AS145_12195	ENOG4105C76	Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue (By similarity)
AS145_12200	ENOG4108DG9	Smr protein MutS2
AS145_12210	ENOG4105BZU	Histidine kinase
AS145_12215	ENOG4105DKJ	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
AS145_12240	ENOG4108Z8G	Alkylphosphonate utilization operon protein PhnA
AS145_12270	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
AS145_12290	ENOG4105DUC	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division (By similarity)
AS145_12295	ENOG4105DAH	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF (By similarity)
AS145_12305	ENOG4106371	Methyltransferase
AS145_12310	ENOG4107S90	membrAne
AS145_12320	ENOG4105CTQ	phosphohexokinase
AS145_12325	ENOG4105CH2	amidohydrolase
AS145_12330	ENOG4105PAD	Hydrolase
AS145_12335	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
AS145_12390	ENOG4105CPB	ATP-dependent endonuclease of the OLD family
AS145_12405	ENOG4105VP0	transcriptional regulator, lysR family
AS145_12410	ENOG4105EJ9	Membrane
AS145_12415	ENOG4106IUH	DTW domain containing protein
AS145_12425	ENOG4105CPF	Cell wall formation (By similarity)
AS145_12435	ENOG4108V06	Glutathione peroxidase
AS145_12440	ENOG4105C1J	atp-dependent rna helicase
AS145_12445	ENOG4105K5X	acetyltransferase
AS145_12455	ENOG4105KK4	UPF0060 membrane protein
AS145_12485	ENOG41061CK	Antibiotic biosynthesis monooxygenase
AS145_12490	ENOG4107XGF	functions in a salvage pathway. Uses pyridoxamine (By similarity)
AS145_12510	ENOG4105D1N	poly(r)-hydroxyalkanoic acid synthase, class
AS145_12520	ENOG4105WQ3	Rna-binding protein
AS145_12530	ENOG4105BZ1	(ABC) transporter
AS145_12535	ENOG4105BZ1	(ABC) transporter
AS145_12540	ENOG4105BZU	Histidine kinase
AS145_12545	ENOG4105K63	Thioredoxin
AS145_12550	ENOG4105C8P	)-transporter
AS145_12555	ENOG4107QQN	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties (By similarity)
AS145_12590	ENOG4105C44	Serine transporter
AS145_12595	ENOG4107QV7	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system) (By similarity)
AS145_12600	ENOG4105C9U	ATP-dependent DNA helicase RecQ
AS145_12605	ENOG4105CYN	Serine protein kinase
AS145_12615	ENOG4105ED1	spovr family
AS145_12620	ENOG4105C05	Multifunctional regulator of fatty acid metabolism (By similarity)
AS145_12625	ENOG4105DKR	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity)
AS145_12630	ENOG410635M	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein (By similarity)
AS145_12635	ENOG4105DQR	SNARE associated Golgi
AS145_12645	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
AS145_12655	ENOG4105D0C	transport protein
AS145_12660	ENOG4105CHQ	Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella (By similarity)
AS145_12680	ENOG4108MRH	transcriptional regulatory protein
AS145_12685	ENOG4105CEQ	signal transduction histidine kinase regulating citrate malate metabolism
AS145_12690	ENOG4105E2R	ROK family
AS145_12695	ENOG4105C8Q	Methyl-accepting chemotaxis
AS145_12700	ENOG4105K5B	UPF0225 protein
AS145_12705	ENOG4107R5Y	anaerobic glycerol-3-phosphate dehydrogenase, subunit A
AS145_12710	ENOG4108KJ0	anaerobic glycerol-3-phosphate dehydrogenase, subunit B
AS145_12715	ENOG4105CHG	glycolate oxidase (iron-sulfur subunit)
AS145_12735	ENOG4105JJ8	Cytochrome c nitrite reductase, pentaheme subunit
AS145_12740	ENOG4105D3S	4Fe-4S Ferredoxin, iron-sulfur binding domain protein
AS145_12745	ENOG4105DVI	reductase, NrfD
AS145_12750	ENOG4105DA4	cytochrome c-type biogenesis protein
AS145_12755	ENOG4107QX9	Thiol disulfide interChange protein
AS145_12760	ENOG4108DMF	Cytochrome C biogenesis protein
AS145_12765	ENOG4108Z4K	mutator MutT protein
AS145_12770	ENOG41061WM	D-Alanyl-D-Alanine
AS145_12775	ENOG4105C0F	tryptophanase EC 4.1.99.1
AS145_12780	ENOG4105EXX	Deoxyribodipyrimidine photolyase-related protein
AS145_12785	ENOG4105MWK	D-amino acid dehydrogenase, small subunit
AS145_12800	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
AS145_12810	ENOG4105DSS	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation (By similarity)
AS145_12815	ENOG4105DZ2	Transcriptional regulator
AS145_12825	ENOG4105E0K	tonB-dependent siderophore receptor
AS145_12830	ENOG4108XW0	May be a transcriptional activator of genes involved in the multiple antibiotic resistance (Mar) phenotype. It can also activate genes such as sodA, zwf and micF
AS145_12840	ENOG4105CR8	Transcriptional regulator
AS145_12845	ENOG4108RYK	Nad-dependent epimerase dehydratase
AS145_12855	ENOG4105C28	cystathionine
AS145_12865	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
AS145_12870	ENOG4105KPY	Small multidrug resistance protein
AS145_12875	ENOG4105DDY	UPF0142 protein ycaO
AS145_12880	ENOG4105TMB	Formate nitrite transporter
AS145_12885	ENOG4105C6N	Formate acetyltransferase
AS145_12890	ENOG4108KAZ	Involved in phosphonate degradation (By similarity)
AS145_12895	ENOG4108JPW	Aminotransferase
AS145_12900	ENOG4107STF	Involved in phosphonate degradation (By similarity)
AS145_12910	ENOG4105C4Y	ABC transporter
AS145_12920	ENOG4107RCV	ABC transporter, permease
AS145_12925	ENOG4105CJP	fad dependent oxidoreductase
AS145_12940	ENOG4105CH8	Succinyl-CoA ligase ADP-forming subunit alpha
AS145_12945	ENOG4105CMV	Succinyl-CoA synthetase subunit beta
AS145_12950	ENOG4105C7S	Dehydrogenase
AS145_12955	ENOG4105C7P	2-oxoglutarate dehydrogenase, E1
AS145_12960	ENOG4105E33	succinate dehydrogenase
AS145_12965	ENOG4105C00	Succinate dehydrogenase (Flavoprotein subunit)
AS145_12970	ENOG4105N1I	succinate dehydrogenase, hydrophobic membrane anchor protein
AS145_12975	ENOG4108UTY	succinate dehydrogenase, cytochrome b556 subunit
AS145_12980	ENOG4105BZN	citrate synthase
AS145_12995	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
AS145_13000	ENOG4105CWG	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34 (By similarity)
AS145_13010	ENOG4105CEE	C4-dicarboxylate transporter
AS145_13025	ENOG4108VKG	metal-dependent hydrolase
AS145_13040	ENOG4105NRA	50s ribosomal protein l31 type b
AS145_13050	ENOG4105EUB	pirin domain protein
AS145_13055	ENOG4105HEI	LysR family (Transcriptional regulator
AS145_13065	ENOG4105CNN	ABC, transporter
AS145_13075	ENOG4105DMK	Periplasmic binding protein LacI transcriptional regulator
AS145_13080	ENOG4105EF1	ribulokinase
AS145_13090	ENOG4105CAC	Catalyzes the conversion of L-arabinose to L-ribulose (By similarity)
AS145_13095	ENOG4105CJB	Exodeoxyribonuclease I
AS145_13105	ENOG4107R49	K07407 alpha-galactosidase EC 3.2.1.22
AS145_13115	ENOG41067MG	lrgb family
AS145_13120	ENOG4107T42	This enzyme scavenge exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis (By similarity)
AS145_13125	ENOG4108IQE	Amp-dependent synthetase and ligase
AS145_13130	ENOG4105MH2	YfcL protein
AS145_13140	ENOG4105EE5	Membrane protein terC
AS145_13145	ENOG41090EK	ompa motb domain protein
AS145_13150	ENOG4108KHX	Diguanylate cyclase
AS145_13155	ENOG4108WS1	
AS145_13165	ENOG41090A4	Pterin carbinolamine dehydratase
AS145_13170	ENOG41090A4	Pterin carbinolamine dehydratase
AS145_13175	ENOG4105MIR	Phenylalanine 4-monooxygenase
AS145_13180	ENOG4106K28	UPF0283 membrane protein
AS145_13185	ENOG4105CM6	amino acid regulated cytosolic protein
AS145_13195	ENOG4105YYT	phage shock protein B
AS145_13200	ENOG41087YS	Phage shock protein A
AS145_13205	ENOG4105E51	psp operon transcriptional activator
AS145_13210	ENOG4108J59	Extracellular solute-binding protein, family 5
AS145_13215	ENOG4108I5W	peptide transport system, permease protein
AS145_13220	ENOG4108EU3	peptide transport system, permease
AS145_13225	ENOG4108JQ3	Peptide ABC transporter ATP-binding protein
AS145_13230	ENOG4108JQ2	peptide transport system atp-binding protein
AS145_13235	ENOG4105FR9	TRNA-(Ms 2 io 6 A)-hydroxylase
AS145_13240	ENOG4105CBA	glutamine phosphoribosylpyrophosphate amidotransferase
AS145_13245	ENOG4105E96	Colicin v production protein
AS145_13250	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
AS145_13260	ENOG4105D1H	recombination factor protein RarA
AS145_13265	ENOG4107Y7W	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) (By similarity)
AS145_13270	ENOG4105CNU	cell division protein FtsK
AS145_13275	ENOG4105EW9	transcriptional regulator AsnC family
AS145_13280	ENOG4105C3M	thioredoxin reductase
AS145_13285	ENOG4105BZU	Histidine kinase
AS145_13290	ENOG4107MBR	17 kDa surface antigen
AS145_13295	ENOG4108R4Z	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine (By similarity)
AS145_13300	ENOG4105DWA	May conjugate Arg from its aminoacyl-tRNA to the N- termini of proteins containing an N-terminal aspartate or glutamate
AS145_13305	ENOG4105K9U	however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity)
AS145_13310	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
AS145_13315	ENOG4105KAE	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation (By similarity)
AS145_13320	ENOG4105VEQ	Cold shock protein
AS145_13325	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
AS145_13355	ENOG4105CS6	Rhs element vgr protein
AS145_13390	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
AS145_13460	ENOG4105CS6	Rhs element vgr protein
AS145_13465	ENOG4108WC9	type VI secretion system effector, hcp1 family
AS145_13475	ENOG4108RMJ	sensory transduction regulator
AS145_13485	ENOG4107104	thymidine kinase
AS145_13490	ENOG4107S6Z	Na H antiporter
AS145_13500	ENOG4108WBT	adenosyltransferase
AS145_13505	ENOG4105VRT	cytoplasmic protein
AS145_13510	ENOG4105EIZ	Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity)
AS145_13515	ENOG4105FD2	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) (By similarity)
AS145_13530	ENOG4106EG9	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) (By similarity)
AS145_13535	ENOG4105CFV	Tetratricopeptide repeat protein
AS145_13545	ENOG41080YA	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
AS145_13550	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
AS145_13555	ENOG4105CAT	Cytidine monophosphate kinase
AS145_13560	ENOG4108JEN	Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate (By similarity)
AS145_13565	ENOG4107R11	Transcriptional regulator
AS145_13570	ENOG4105CMU	LysR family (Transcriptional regulator
AS145_13575	ENOG4105D2S	major facilitator superfamily
AS145_13590	ENOG4108DBC	nitroreductase
AS145_13595	ENOG4105BZU	Histidine kinase
AS145_13605	ENOG4105CBN	LysR family transcriptional regulator
AS145_13610	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
AS145_13635	ENOG4107RGM	aldo keto reductase
AS145_13640	ENOG4105VFU	Rna-binding protein
AS145_13650	ENOG4105HPZ	Involved in the removal of murein from the sacculus. May also facilitate integration of nascent murein strands into the sacculus by cleaving the peptide bonds between neighboring strands in mature murein (By similarity)
AS145_13660	ENOG4105HA9	of methanol dehydrogenase type
AS145_13675	ENOG4105E14	MotA TolQ exbB proton channel
AS145_13680	ENOG4105ER2	Ompa motb domain protein
AS145_13685	ENOG4105KWU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
AS145_13690	ENOG4105ES3	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
AS145_13695	ENOG4105CQV	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
AS145_13700	ENOG4105GKE	subunit e
AS145_13705	ENOG4107QIZ	NADH dehydrogenase
AS145_13710	ENOG4108IEH	NADH dehydrogenase subunit g
AS145_13715	ENOG4105CMZ	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone (By similarity)
AS145_13720	ENOG4105P3U	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
AS145_13725	ENOG4107UFS	subunit j
AS145_13730	ENOG41080EA	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
AS145_13735	ENOG4105D65	subunit l
AS145_13740	ENOG4105C8S	subunit m
AS145_13745	ENOG4105CNR	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
AS145_13755	ENOG4107QIK	phosphoribosylformylglycinamidine synthase
AS145_13760	ENOG4105CHQ	Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella (By similarity)
AS145_13765	ENOG4105VPD	cellular component movement
AS145_13770	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
AS145_13775	ENOG4105CNE	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
AS145_13780	ENOG4105N21	Membrane
AS145_13785	ENOG4105CUT	histidyl-tRNA synthetase
AS145_13790	ENOG4105C4E	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (By similarity)
AS145_13795	ENOG4105HSZ	Cytoskeletal protein that is involved in cell-shape control through regulation of the length of the long axis (By similarity)
AS145_13805	ENOG4105C55	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
AS145_13810	ENOG4108UGX	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity)
AS145_13815	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
AS145_13825	ENOG4108ZIT	Ferredoxin, 2FE-2S
AS145_13830	ENOG4105C9I	Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB
AS145_13835	ENOG4108SWN	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA (By similarity)
AS145_13840	ENOG4108Z4V	iron-sulfur cluster assembly
AS145_13845	ENOG4107XTC	May be involved in the formation or repair of Fe-S clusters present in iron-sulfur proteins
AS145_13850	ENOG4105C3J	Cysteine desulfurase
AS145_13870	ENOG4105XPQ	lipid carrier protein
AS145_13875	ENOG4105CFP	Peptidase U32
AS145_13880	ENOG4106RZ4	Peptidase U32
AS145_13895	ENOG4107RAB	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
AS145_13900	ENOG4107QN8	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
AS145_13905	ENOG4105VIE	preprotein translocase, subunit YajC
AS145_13910	ENOG4105C6U	Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity)
AS145_13915	ENOG4105E2N	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) (By similarity)
AS145_13920	ENOG4105W87	Cbs domain
AS145_13925	ENOG4105D3R	alkyl hydroperoxide reductase
AS145_13935	ENOG4108ISG	Major Facilitator
AS145_13950	ENOG4105K89	arsenate reductase
AS145_13955	ENOG4105D6J	arsenicaL-resistance protein
AS145_13960	ENOG41085FC	arsR family transcriptional regulator
AS145_13965	ENOG4105CBI	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
AS145_13970	ENOG4105KE9	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity)
AS145_13975	ENOG4105D43	The glycine cleavage system catalyzes the degradation of glycine (By similarity)
AS145_13980	ENOG4105EAK	ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family
AS145_13985	ENOG4105D0A	hydroxylase
AS145_13995	ENOG4107YUN	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division (By similarity)
AS145_14000	ENOG4105E5M	Multidrug resistance protein D
AS145_14005	ENOG4105CYM	Glutathione S-transferase
AS145_14020	ENOG4108NVR	Methyl-accepting chemotaxis
AS145_14035	ENOG4105DUF	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively (By similarity)
AS145_14050	ENOG4105C5E	polysaccharide biosynthesis protein
AS145_14070	ENOG4105CDM	Glutamate-1-semialdehyde aminotransferase
AS145_14105	ENOG4105MQ3	flagellar protein FliS
AS145_14120	ENOG4105I03	Flagellin
AS145_14135	ENOG4105I03	Flagellin
AS145_14140	ENOG4105I03	Flagellin
AS145_14145	ENOG4105EN6	Membrane
AS145_14155	ENOG4105D8I	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS (By similarity)
AS145_14165	ENOG4108JQB	penicillin-binding protein 1C
AS145_14170	ENOG4105DN3	alpha-2-macroglobulin domain protein
AS145_14175	ENOG4105CH2	amidohydrolase
AS145_14180	ENOG4105IPI	Membrane
AS145_14185	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
AS145_14190	ENOG4105J12	Multidrug resistance protein mdtN
AS145_14205	ENOG4107QMW	pyridine nucleotide-disulfide oxidoreductase
AS145_14210	ENOG4105BZU	Histidine kinase
AS145_14215	ENOG4105F1A	Pyruvate formate-lyase
AS145_14230	ENOG4105DSP	amino acid AbC transporter
AS145_14235	ENOG4106PMH	Extracellular solute-binding protein family 3
AS145_14240	ENOG4108JEH	abc transporter atp-binding protein
AS145_14245	ENOG4105DWU	Membrane
AS145_14250	ENOG4105DYB	Isoaspartyl dipeptidase
AS145_14255	ENOG4108ZYK	Acyl carrier protein phosphodiesterase
AS145_14270	ENOG4105K89	arsenate reductase
AS145_14280	ENOG4105ERG	peptidase m48, ste24p
AS145_14285	ENOG41082K8	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Interacts with IscS and stimulates its activity. Then, accepts a sulfur from IscS and transfers it in turn to TusD (By similarity)
AS145_14305	ENOG4105CSR	polyphosphate kinase 2
AS145_14310	ENOG4108IJ9	(ABC) transporter
AS145_14315	ENOG4105EG2	ABC transporter, permease
AS145_14320	ENOG4105D56	permease protein
AS145_14325	ENOG4107FKK	extracellular solute-binding protein family 1
AS145_14330	ENOG4106V8H	Nucleoid-associated protein
AS145_14335	ENOG4105PAN	UPF0352 protein
AS145_14340	ENOG4105E68	Sulfatase
AS145_14345	ENOG4105D05	Receptor
AS145_14350	ENOG4105CUG	Oligopeptidase b
AS145_14370	ENOG4108QSZ	General inhibitor of pancreatic serine proteases inhibits chymotrypsin, trypsin, elastases, factor X, kallikrein as well as a variety of other proteases (By similarity)
AS145_14375	ENOG4108WFC	UPF0438 protein yifE
AS145_14380	ENOG4105CVI	Transcriptional regulator
AS145_14390	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
AS145_14395	ENOG4106MZZ	glycerophosphoryl diester phosphodiesterase
AS145_14400	ENOG4105C6V	Glycerol-3-phosphate dehydrogenase
AS145_14405	ENOG4105E98	transcriptional regulator DeoR family
AS145_14410	ENOG4105CXY	transporter
AS145_14415	ENOG4105D8C	Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity)
AS145_14420	ENOG4108JQ0	Key enzyme in the regulation of glycerol uptake and metabolism (By similarity)
AS145_14425	ENOG4105HEI	LysR family (Transcriptional regulator
AS145_14445	ENOG4105CV8	reductase
AS145_14450	ENOG4105F27	Major Facilitator
AS145_14460	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
AS145_14465	ENOG4105C4M	(Ubiquinol oxidase) subunit I
AS145_14470	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
AS145_14480	ENOG4108Q2J	Inner membrane protein YebE
AS145_14500	ENOG4105D2S	major facilitator superfamily
AS145_14515	ENOG4105DJ2	Major Facilitator Superfamily
AS145_14520	ENOG4105FE9	pseudouridine synthase
AS145_14525	ENOG4105D82	Glutamate dehydrogenase
AS145_14545	ENOG4105CFI	type iii restriction protein res subunit
AS145_14555	ENOG4105WWK	YheO domain protein
AS145_14560	ENOG4105CEM	UPF0597 protein
AS145_14565	ENOG4105KME	endoribonuclease L-psp
AS145_14570	ENOG4105C44	Serine transporter
AS145_14575	ENOG4108NVR	Methyl-accepting chemotaxis
AS145_14590	ENOG4105DP5	Catalyzes the biosynthesis of agmatine from arginine (By similarity)
AS145_14595	ENOG4105D42	Cleaves the N-terminal amino acid of tripeptides (By similarity)
AS145_14620	ENOG4108YYC	ycei family
AS145_14625	ENOG4105CC0	LysR family Transcriptional regulator
AS145_14635	ENOG4105CKU	formyltetrahydrofolate synthetase
AS145_14640	ENOG4105C8Q	Methyl-accepting chemotaxis
AS145_14645	ENOG4105EUJ	GTP cyclohydrolase i
AS145_14650	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
AS145_14655	ENOG4105D06	uba thif-type nad fad binding protein
AS145_14660	ENOG4105D3C	The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters (By similarity)
AS145_14665	ENOG4105CGB	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system (By similarity)
AS145_14670	ENOG4105E0C	molybdate abc transporter
AS145_14675	ENOG4108S6J	ABC transporter, periplasmic molybdate-binding protein
AS145_14680	ENOG4108ZAF	Molybdopterin
AS145_14685	ENOG4105M00	molybdopterin converting factor, subunit 1
AS145_14690	ENOG4108YXW	Together with MoaA, is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
AS145_14695	ENOG4108RIR	Molybdenum cofactor biosynthesis protein
AS145_14700	ENOG4105CUW	cytochrome C-TYPE protein
AS145_14710	ENOG4105GXZ	Ferredoxin-type protein NapH
AS145_14715	ENOG4108BGM	Quinol dehydrogenase periplasmic component
AS145_14720	ENOG4107QIW	Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity)
AS145_14730	ENOG4108ZNS	ferredoxin-type protein NapF
AS145_14735	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
AS145_14740	ENOG4105BZU	Histidine kinase
AS145_14745	ENOG4105WH1	Two component transcriptional regulator luxr family
AS145_14755	ENOG4105BZU	Histidine kinase
AS145_14765	ENOG4105CHW	UPF0052 protein
AS145_14775	ENOG4105E7A	Glutamine amidotransferase
AS145_14780	ENOG4105F55	Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate (By similarity)
AS145_14785	ENOG4107QPN	acyl-Coa dehydrogenase
AS145_14790	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
AS145_14800	ENOG4108JDX	DNA polymerase iii, epsilon subunit
AS145_14805	ENOG4108UMW	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
AS145_14810	ENOG4105D1A	Methyltransferase
AS145_14815	ENOG4108RW0	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
AS145_14820	ENOG4105E9H	Lytic Murein transglycosylase
AS145_14835	ENOG4105NAU	thioesterase Superfamily protein
AS145_14845	ENOG41060NJ	transcriptional regulator
AS145_14850	ENOG4107SC1	transglycosylase
AS145_14855	ENOG4105BZU	Histidine kinase
AS145_14860	ENOG4108WPH	sigma 54 modulation protein ribosomal protein S30EA
AS145_14885	ENOG4105CFU	surface antigen
AS145_14895	ENOG4105KQ5	peptidylprolyl cis-trans isomerase
AS145_14910	ENOG4107ZN8	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity (By similarity)
AS145_14920	ENOG4105VNH	ABC transporter solute-binding protein
AS145_14930	ENOG4108VGW	abc transporter atp-binding protein
AS145_14935	ENOG4108T9J	Cdp-alcohol phosphatidyltransferase
AS145_14940	ENOG4105CVE	Lytic murein transglycosylase
AS145_14955	ENOG4107QIX	Phosphoglucomutase (EC 5.4.2.2
AS145_14960	ENOG4107CDU	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated (By similarity)
AS145_14965	ENOG4105EV9	Alpha Beta Hydrolase
AS145_14975	ENOG4105NNH	LexA regulated protein
AS145_14980	ENOG4105MHQ	Low-potential electron donor to a number of redox enzymes (By similarity)
AS145_14990	ENOG41090R7	Ferric uptake
AS145_14995	ENOG4105CX6	glutaminyL-tRNA synthetase
AS145_15000	ENOG4105E2D	ec 3.2.1.52
AS145_15005	ENOG4105CI1	PTS System
AS145_15010	ENOG4105CKA	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion (By similarity)
AS145_15015	ENOG4105CE4	GlcNAc 6-P deacetylase
AS145_15020	ENOG4105E2R	ROK family
AS145_15025	ENOG4105DIJ	Phosphoethanolamine transferase
AS145_15030	ENOG4105CDY	transcriptional regulatory protein
AS145_15035	ENOG4105C9M	aspartyl-trna synthetase
AS145_15040	ENOG41081XQ	Conserved Protein
AS145_15045	ENOG4105DA6	Catalyzes the conversion of 5-methoxyuridine (mo5U) to uridine-5-oxyacetic acid (cmo5U) at position 34 in tRNA. May also participate in the methylation of uridine-5-oxyacetic acid (cmo5U) to uridine-5-oxyacetic acid methyl ester (mcmo5U) (By similarity)
AS145_15050	ENOG4105PFA	Catalyzes the conversion of 5-hydroxyuridine (ho5U) to 5-methoxyuridine (mo5U) at position 34 in tRNA (By similarity)
AS145_15070	ENOG4105D3R	alkyl hydroperoxide reductase
AS145_15075	ENOG4105C5Q	Transcriptional regulator
AS145_15085	ENOG4107TT5	NLP P60 protein
AS145_15095	ENOG4107RGH	Aldehyde dehydrogenase
AS145_15100	ENOG4107Z3H	Transcriptional regulator, TetR family
AS145_15120	ENOG4105C6T	cysteine synthase
AS145_15140	ENOG4105UQX	Mate efflux family protein
AS145_15160	ENOG4107SQI	penicillin amidase
AS145_15165	ENOG4105D95	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin (By similarity)
AS145_15175	ENOG4105QVC	MOSC domain-containing protein
AS145_15175	ENOG4105QVC	MOSC domain-containing protein
AS145_15180	ENOG4107SDU	Methyl-accepting chemotaxis
AS145_15185	ENOG4105D0M	Protease HtpX homolog
AS145_15190	ENOG4105E78	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity)
AS145_15195	ENOG410626R	Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity)
AS145_15200	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
AS145_15205	ENOG4105CZF	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism (By similarity)
AS145_15225	ENOG4105C5S	asparaginyl-tRNA synthetase
AS145_15230	ENOG4105DS2	Anaerobic c4-dicarboxylate transporter
AS145_15245	ENOG4105CEE	C4-dicarboxylate transporter
AS145_15260	ENOG4105KUZ	arsenate reductase
AS145_15265	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
AS145_15275	ENOG4105C3N	Participates in control of cell volume in low-osmolarity conditions (By similarity)
AS145_15295	ENOG410829K	Lysine exporter protein (Lyse ygga)
AS145_15300	ENOG4108NVR	Methyl-accepting chemotaxis
AS145_15305	ENOG4105RX8	Protein of unknown function (DUF1523)
AS145_15320	ENOG4105DU0	nucleoside hydrolase
AS145_15325	ENOG4105D3G	Pseudouridine synthase
AS145_15330	ENOG4107SXA	Phosphorylase
AS145_15335	ENOG4105C0A	alcohol dehydrogenase
AS145_15415	ENOG4105YRI	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
AS145_15420	ENOG4105K4T	epimerase
AS145_15425	ENOG4105VDB	UPF0125 protein
AS145_15430	ENOG4108Z1B	Cyclase dehydrase
AS145_15435	ENOG4108UH4	Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity)
AS145_15515	ENOG4105EFV	Major head subunit
AS145_15520	ENOG4108TVE	i protein
AS145_15540	ENOG4105QIB	mu-like prophage Flumu protein gp29
AS145_15545	ENOG4105CF2	Mu-like prophage FluMu protein GP28
AS145_15550	ENOG4108Z6H	mu-like prophage Flumu protein gp27
AS145_15655	ENOG4108F3G	Type I restriction-modification system, R subunit
AS145_15695	ENOG4105W8I	Transcriptional regulator
AS145_15705	ENOG4105BZC	d-serine deaminase
AS145_15710	ENOG4108HMX	isocitrate dehydrogenase (NADP)
AS145_15715	ENOG4106R3P	AraC family transcriptional regulator
AS145_15720	ENOG4105EIP	mannose-6-phosphate isomerase
AS145_15730	ENOG4105DM4	PTS System
AS145_15740	ENOG4105C87	Aminotransferase class I and II
AS145_15745	ENOG4105CI1	PTS System
AS145_15750	ENOG4107P2S	Transcriptional regulator
AS145_15765	ENOG4105KEG	ribosomal-protein-alanine acetyltransferase
AS145_15785	ENOG4105DM4	PTS System
AS145_15790	ENOG4105CXY	transporter
AS145_15795	ENOG4108YRF	PTS System
AS145_15805	ENOG4108R99	pseudouridine synthase
AS145_15815	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
AS145_15820	ENOG41075W9	High frequency lysogenization protein HflD homolog
AS145_15825	ENOG4107QTF	adenylosuccinate lyase
AS145_15830	ENOG4105EZE	Cupin 4 family protein
AS145_15840	ENOG4108YYD	acetyltransferase
AS145_15855	ENOG4108S7T	Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) (By similarity)
AS145_15875	ENOG4105M2J	Glutaredoxin
AS145_15880	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
AS145_15885	ENOG410903C	(LipO)protein
AS145_15890	ENOG4105KWW	Biogenesis protein
AS145_15895	ENOG4105KWW	Biogenesis protein
AS145_15900	ENOG4107QX9	Thiol disulfide interChange protein
AS145_15905	ENOG4105DA4	cytochrome c-type biogenesis protein
AS145_15910	ENOG4108ZKK	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH (By similarity)
AS145_15915	ENOG4105X3C	heme exporter protein
AS145_15920	ENOG41060IM	Heme exporter protein
AS145_15925	ENOG4105CA5	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes (By similarity)
AS145_15940	ENOG4108V3W	Chemotaxis protein, CheW
AS145_15950	ENOG4107QJE	Chromosome Partitioning Protein
AS145_15955	ENOG4108SEK	ompa motb domain protein
AS145_15960	ENOG4105E14	MotA TolQ exbB proton channel
AS145_15965	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
AS145_15970	ENOG4105CBS	Chea signal transduction histidine kinase
AS145_15975	ENOG4108KCC	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P) (By similarity)
AS145_15980	ENOG4108VYJ	response regulator receiver protein
AS145_15985	ENOG4105DN4	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
AS145_15995	ENOG4105FZW	flagellar biosynthesis regulator FlhF
AS145_16000	ENOG4105D7B	Flagellar biosynthesis protein flha
AS145_16005	ENOG4105D00	flagellar biosynthetic protein flhB
AS145_16010	ENOG4105D19	Role in flagellar biosynthesis (By similarity)
AS145_16015	ENOG4105VS8	Flagellar biosynthetic protein fliq
AS145_16020	ENOG4105CN7	Flagellar biosynthetic protein FliP
AS145_16025	ENOG4105VTB	flagellar biosynthesis protein fliO
AS145_16030	ENOG4105DD5	Flagellar motor switch protein
AS145_16035	ENOG4105D24	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
AS145_16055	ENOG4108JIR	Flagellum-specific ATP synthase
AS145_16065	ENOG4105CS3	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
AS145_16070	ENOG4105C1F	The M ring may be actively involved in energy transduction (By similarity)
AS145_16075	ENOG4105VQ0	flagellar hook-basal body complex protein fliE
AS145_16085	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
AS145_16090	ENOG4105CBM	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 (By similarity)
AS145_16100	ENOG4105EUK	rtx toxin RtxA
AS145_16115	ENOG4108JJA	ABC, transporter
AS145_16120	ENOG4105C42	Type I secretion membrane fusion protein (HlyD
AS145_16125	ENOG4108JJA	ABC, transporter
AS145_16130	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
AS145_16145	ENOG4106KNT	transcriptional regulator
AS145_16150	ENOG4105CA9	Pyruvate kinase
AS145_16160	ENOG4105BZS	acriflavin resistance protein
AS145_16165	ENOG4107QPN	acyl-Coa dehydrogenase
AS145_16175	ENOG4107SSZ	Phosphatase
AS145_16185	ENOG4107QKC	Oxidoreductase alpha (molybdopterin) subunit
AS145_16190	ENOG4107H9G	Necessary for formate dehydrogenase activity (By similarity)
AS145_16195	ENOG4105CBN	LysR family transcriptional regulator
AS145_16215	ENOG4105KNY	Microcompartments protein
AS145_16220	ENOG4105KNY	Microcompartments protein
AS145_16225	ENOG4105KNY	Microcompartments protein
AS145_16230	ENOG4108EKI	Dehydrogenase
AS145_16240	ENOG4108EKI	Dehydrogenase
AS145_16245	ENOG4105C6N	Formate acetyltransferase
AS145_16250	ENOG4105F1A	Pyruvate formate-lyase
AS145_16255	ENOG4105KNY	Microcompartments protein
AS145_16260	ENOG4108VPX	Involved in 1,2-propanediol (1,2-PD) degradation by catalyzing the conversion of propanoyl-CoA to propanoyl-phosphate (By similarity)
AS145_16305	ENOG4108R66	Conserved Protein
AS145_16310	ENOG4107RJ1	sodium solute
AS145_16320	ENOG4105C9S	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P) (By similarity)
AS145_16325	ENOG4105QEK	Transcriptional regulator
AS145_16330	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
AS145_16335	ENOG4105C1X	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity (By similarity)
AS145_16340	ENOG4105E98	transcriptional regulator DeoR family
AS145_16345	ENOG4105EDR	glucose galactose transporter
AS145_16350	ENOG4105EHF	Converts the aldose L-fucose into the corresponding ketose L-fuculose (By similarity)
AS145_16355	ENOG4105CMG	Carbohydrate kinase
AS145_16365	ENOG4105NWF	RbsD or FucU transport
AS145_16375	ENOG4108JQ5	ABC transporter
AS145_16380	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
AS145_16390	ENOG4105DEF	Extracellular solute-binding protein, family 5
AS145_16400	ENOG4107N1Q	ErfK YbiS YcfS YnhG family protein
AS145_16415	ENOG4105EBA	Specifically methylates the adenine in position 1618 of 23S rRNA (By similarity)
AS145_16420	ENOG4107TT5	NLP P60 protein
AS145_16430	ENOG4107QR8	Thioredoxin
AS145_16440	ENOG4105C66	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity)
AS145_16445	ENOG4105CIY	formyltetrahydrofolate deformylase
AS145_16455	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
AS145_16470	ENOG4108VC8	Peptidase family M23
AS145_16480	ENOG4105E4C	Lytic transglycosylase catalytic
AS145_16485	ENOG4105D8C	Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity)
AS145_16490	ENOG4105NHU	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group (By similarity)
AS145_16500	ENOG4105EP9	oxidoreductase
AS145_16520	ENOG4105CCT	upf0313 protein
AS145_16530	ENOG4105BZS	acriflavin resistance protein
AS145_16535	ENOG4105J12	Multidrug resistance protein mdtN
AS145_16540	ENOG4105BZU	Histidine kinase
AS145_16545	ENOG4105D78	K07001 NTE family protein
AS145_16550	ENOG4105C8J	)-transporter
AS145_16565	ENOG4105UYK	outer membrane protein a
AS145_16570	ENOG4105UYK	outer membrane protein a
AS145_16575	ENOG4105UYK	outer membrane protein a
AS145_16580	ENOG4107R1I	NAD-dependent malic enzyme
AS145_16585	ENOG4105ECQ	AraC Family Transcriptional Regulator
AS145_16590	ENOG4105UQX	Mate efflux family protein
AS145_16595	ENOG4105RKX	Protein of unknown function (DUF2498)
AS145_16600	ENOG4105BZU	Histidine kinase
AS145_16605	ENOG4105C2W	permease
AS145_16610	ENOG4108KMH	lipoate-protein ligase a
AS145_16615	ENOG4105BZG	amino acid carrier protein
AS145_16640	ENOG4105PTV	Nudix Hydrolase
AS145_16660	ENOG4105CJ1	ABC, transporter
AS145_16665	ENOG4108V1T	peptidylprolyl cis-trans isomerase
AS145_16670	ENOG4106N3A	copper homeostasis protein cutc
AS145_16685	ENOG4105ERG	peptidase m48, ste24p
AS145_16695	ENOG4105BZU	Histidine kinase
AS145_16700	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
AS145_16705	ENOG4108ZI4	Glyoxalase Bleomycin resistance protein (Dioxygenase
AS145_16710	ENOG4105C04	l-carnitine dehydratase bile acid-inducible protein F
AS145_16715	ENOG4105C1G	acyl-Coa dehydrogenase
AS145_16720	ENOG4108JU9	GAF modulated sigma54 specific transcriptional regulator Fis family
AS145_16725	ENOG4105C26	Dehydrogenase
AS145_16735	ENOG4108IPJ	Membrane
AS145_16740	ENOG4106YYS	transcriptional regulatory protein
AS145_16745	ENOG4105CEQ	signal transduction histidine kinase regulating citrate malate metabolism
AS145_16750	ENOG4107R1I	NAD-dependent malic enzyme
AS145_16755	ENOG4105D2K	citrate carrier protein
AS145_16760	ENOG4108US0	Transcription regulator that can specifically activate or repress expression of target genes (By similarity)
AS145_16765	ENOG4105J12	Multidrug resistance protein mdtN
AS145_16790	ENOG4108RDD	Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine (By similarity)
AS145_16795	ENOG4105CJD	(Anaerobic) ribonucleoside-triphosphate reductase
AS145_16805	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
AS145_16815	ENOG4105CDB	Required for chromosome condensation and partitioning (By similarity)
AS145_16820	ENOG4105EXN	Sulfate transport protein CysZ
AS145_16825	ENOG4105EN6	Membrane
AS145_16835	ENOG4105EAQ	(twin-arginine translocation) pathway signal
AS145_16840	ENOG4105DIT	ErfK YbiS YcfS YnhG family protein
AS145_16870	ENOG4107T9C	Alpha amylase catalytic region
AS145_16905	ENOG4105BZU	Histidine kinase
AS145_16910	ENOG4105D3U	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
AS145_16915	ENOG4105C9K	Endothelin-converting enzyme 1
AS145_16925	ENOG4105C5H	ABC transporter
AS145_16930	ENOG4105KNA	-acetyltransferase
AS145_16935	ENOG4105DVH	amino acid
AS145_16940	ENOG4105EXG	Transcriptional regulator
AS145_16950	ENOG4105C44	Serine transporter
AS145_16955	ENOG4105EQ2	LysR family Transcriptional regulator
AS145_16965	ENOG4107XGF	functions in a salvage pathway. Uses pyridoxamine (By similarity)
AS145_16970	ENOG4105CXN	decarboxylase
AS145_16975	ENOG4105D5Q	Arginine ornithine antiporter
AS145_16980	ENOG4108M3R	transcriptional activator CadC
AS145_16985	ENOG4107QM9	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA (By similarity)
AS145_16990	ENOG4105C0B	DNA polymerase III (alpha subunit)
AS145_16995	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
AS145_17000	ENOG4105D0V	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
AS145_17005	ENOG4105DAF	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
AS145_17010	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
AS145_17015	ENOG4105D7M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
AS145_17020	ENOG4108RFI	Molecular chaperone that interacts specifically with outer membrane proteins, thus maintaining the solubility of early folding intermediates during passage through the periplasm (By similarity)
AS145_17030	ENOG4105DZP	Membrane-associated zinc metalloprotease
AS145_17035	ENOG4105CEA	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity)
AS145_17040	ENOG4105KNE	Phosphatidate cytidylyltransferase
AS145_17045	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
AS145_17050	ENOG4108VCV	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity)
AS145_17055	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
AS145_17060	ENOG4105CU7	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity)
AS145_17065	ENOG4105CE9	30S ribosomal protein S2
AS145_17070	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
AS145_17075	ENOG4105E1P	Modifies, by uridylylation or deuridylylation the PII (GlnB) regulatory protein (By similarity)
AS145_17080	ENOG4105DMJ	Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate (By similarity)
AS145_17085	ENOG4108T8E	UPF0325 protein
AS145_17090	ENOG4105CI1	PTS System
AS145_17095	ENOG4107W52	maltose operon periplasmic protein
AS145_17100	ENOG4108KDD	Involved in the transport of maltose and maltodextrins (By similarity)
AS145_17105	ENOG4105QDK	Flavodoxin
AS145_17110	ENOG4105DR9	pseudouridine synthase
AS145_17115	ENOG4105WP7	tRNA pseudouridine synthase C
AS145_17140	ENOG4105EXF	Zn-ribbon-containing, possibly nucleic-acid-binding protein
AS145_17145	ENOG4108T6E	Interacts with the SecY protein in vivo. May bind preferentially to an uncomplexed state of SecY, thus functioning either as a chelating agent for excess SecY in the cell or as a regulatory factor that negatively controls the translocase function (By similarity)
AS145_17150	ENOG4107R1K	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) (By similarity)
AS145_17160	ENOG4105BZU	Histidine kinase
AS145_17165	ENOG4105EWT	decarboxylase family
AS145_17170	ENOG4105CIQ	May have a role in processing of nucleic acids. It is probably not an exonuclease
AS145_17175	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
AS145_17185	ENOG4105EZ6	Catalyzes the 2'-O-methylation at nucleotide C2498 in 23S rRNA (By similarity)
AS145_17190	ENOG4105M08	Membrane
AS145_17200	ENOG4105ETT	transcriptional Regulator, LysR family
AS145_17205	ENOG4105C8Q	Methyl-accepting chemotaxis
AS145_17210	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
AS145_17225	ENOG4105CJ2	(LipO)protein
AS145_17230	ENOG4105D26	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. The first step is catalyzed by NqrF, which accepts electrons from NADH and reduces ubiquinone-1 to ubisemiquinone by a one-electron transfer pathway (By similarity)
AS145_17235	ENOG4108IUB	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
AS145_17240	ENOG4105F5D	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
AS145_17245	ENOG4106I92	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
AS145_17250	ENOG4108J5C	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
AS145_17255	ENOG4105DWQ	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
AS145_17260	ENOG4105M85	Bola protein
AS145_17265	ENOG4105D8J	Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle (By similarity)
AS145_17275	ENOG4108R5K	PPIases accelerate the folding of proteins (By similarity)
AS145_17285	ENOG4105EYM	Major Facilitator superfamily
AS145_17290	ENOG4105DRB	nucleoside-specific channel-forming protein
AS145_17295	ENOG4108VPT	UPF0234 protein
AS145_17300	ENOG4108JZF	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity)
AS145_17305	ENOG4107S0N	DJ-1 family
AS145_17310	ENOG4105C7K	acetolactate synthase
AS145_17345	ENOG4108WC9	type VI secretion system effector, hcp1 family
AS145_17350	ENOG4105VJY	transcriptional regulator
AS145_17360	ENOG4105DRC	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity)
AS145_17365	ENOG4105CMR	udp-glucose 4-epimerase
AS145_17375	ENOG4105EJ7	Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O (By similarity)
AS145_17380	ENOG4108RMU	ferritin dps family protein
AS145_17405	ENOG4105CV9	cyclopropane-fatty-acyl-phospholipid synthase
AS145_17420	ENOG4105EMU	Dehydrogenase
AS145_17430	ENOG4105CVP	deoxyribo-dipyrimidine photolyase
AS145_17435	ENOG4108XDN	Transcriptional regulator
AS145_17440	ENOG4107SEY	Conserved Protein
AS145_17470	ENOG4105CQC	Prephenate dehydratase
AS145_17500	ENOG4108NF7	phage-type endonuclease
AS145_17540	ENOG4105W5Q	DNA repair protein (RadC
AS145_17550	ENOG4105EIZ	Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity)
AS145_17555	ENOG4105FD2	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) (By similarity)
AS145_17570	ENOG4107ZIF	6-carboxy-5,6,7,8-tetrahydropterin synthase
AS145_17585	ENOG4105C9U	ATP-dependent DNA helicase RecQ
AS145_17605	ENOG4105C9U	ATP-dependent DNA helicase RecQ
AS145_17610	ENOG4105BZK	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair (By similarity)
AS145_17635	ENOG4107ZSV	Receptor
AS145_17660	ENOG4108JUA	Transcriptional regulator
AS145_17680	ENOG4105EHG	Permease protein
AS145_17685	ENOG4108W0P	ABC transporter
AS145_17695	ENOG4105DVA	methyltransferase
AS145_17720	ENOG4105D8V	Glucose sorbosone dehydrogenase
AS145_17730	ENOG4105C8Q	Methyl-accepting chemotaxis
AS145_17735	ENOG4105J5J	Outer membrane porin
AS145_17740	ENOG4105E1F	short-chain dehydrogenase reductase
AS145_17760	ENOG4105CTD	carboxy-peptidase
AS145_17775	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
AS145_17780	ENOG4105CFP	Peptidase U32
AS145_17785	ENOG4105N14	lysine exporter protein LysE YggA
AS145_17795	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
AS145_17800	ENOG4105C8Q	Methyl-accepting chemotaxis
AS145_17805	ENOG4108VYJ	response regulator receiver protein
AS145_17815	ENOG4105CBS	Chea signal transduction histidine kinase
AS145_17825	ENOG4108V3W	Chemotaxis protein, CheW
AS145_17830	ENOG4105C8Q	Methyl-accepting chemotaxis
AS145_17835	ENOG4105BZU	Histidine kinase
AS145_17840	ENOG4108Z4W	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis (By similarity)
AS145_17845	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
AS145_17850	ENOG4105C9B	Cysteine desulfurase
AS145_17890	ENOG4108NJZ	Sensory box GGDEF EAL domain protein
AS145_17895	ENOG4105CFP	Peptidase U32
AS145_17900	ENOG4105K5D	4fe-4S ferredoxin iroN-sulfur binding
AS145_17905	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
AS145_17910	ENOG4105CDU	Replicative dna helicase
AS145_17920	ENOG4105BZU	Histidine kinase
AS145_17925	ENOG4105CGH	5'-nucleotidase
AS145_17945	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
AS145_17950	ENOG4108V1T	peptidylprolyl cis-trans isomerase
AS145_17960	ENOG4105VRX	Protein slyX homolog
AS145_17965	ENOG4108YZY	peptidylprolyl cis-trans isomerase
AS145_17970	ENOG4105VKU	nucleicacid-binding protein
AS145_17980	ENOG4107R88	Chemotaxis protein (CheV)
AS145_17985	ENOG4105DNZ	Alpha Beta Hydrolase
AS145_17995	ENOG4105YP7	UPF0270 protein
AS145_18000	ENOG4105C6Y	Udp-glucose 6-dehydrogenase
AS145_18005	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
AS145_18010	ENOG4105CKK	Glycosyl transferase, family 2
AS145_18015	ENOG4108I2E	Bifunctional enzyme that catalyzes the oxidative decarboxylation of UDP-glucuronic acid (UDP-GlcUA) to UDP-4-keto- arabinose (UDP-Ara4O) and the addition of a formyl group to UDP-4- amino-4-deoxy-L-arabinose (UDP-L-Ara4N) to form UDP-L-4-formamido- arabinose (UDP-L-Ara4FN). The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides (By similarity)
AS145_18020	ENOG4105F73	Catalyzes the deformylation of 4-deoxy-4-formamido-L- arabinose-phosphoundecaprenol to 4-amino-4-deoxy-L-arabinose- phosphoundecaprenol. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides (By similarity)
AS145_18025	ENOG4105SA9	Catalyzes the transfer of the L-Ara4N moiety of the glycolipid undecaprenyl phosphate-alpha-L-Ara4N to lipid A. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides (By similarity)
AS145_18030	ENOG41060GT	Translocates 4-amino-4-deoxy-L-arabinose- phosphoundecaprenol (alpha-L-Ara4N-phosphoundecaprenol) from the cytoplasmic to the periplasmic side of the inner membrane (By similarity)
AS145_18035	ENOG4105PE8	Translocates 4-amino-4-deoxy-L-arabinose- phosphoundecaprenol (alpha-L-Ara4N-phosphoundecaprenol) from the cytoplasmic to the periplasmic side of the inner membrane (By similarity)
AS145_18040	ENOG4105CJE	phosphoribulokinase (EC 2.7.1.19)
AS145_18055	ENOG4108UKZ	OsmC family
AS145_18060	ENOG4107RYR	Transcriptional regulator, Crp Fnr family
AS145_18065	ENOG4105DHI	Methyltransferase
AS145_18070	ENOG4108M1A	Chitin-binding protein
AS145_18075	ENOG4108MA4	Peptidase M66
AS145_18085	ENOG4105BZU	Histidine kinase
AS145_18095	ENOG4105VMP	Transcriptional regulator
AS145_18100	ENOG4105D8G	Major Facilitator superfamily
AS145_18105	ENOG4105D05	Receptor
AS145_18125	ENOG4105PYN	Pyridoxamine 5-phosphate oxidase-related
AS145_18130	ENOG41090JE	Utilization Protein
AS145_18140	ENOG4105EHG	Permease protein
AS145_18170	ENOG4105D9N	nucleoside
AS145_18175	ENOG4107U5R	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate (By similarity)
AS145_18195	ENOG4105E4C	Lytic transglycosylase catalytic
AS145_18200	ENOG4105DUF	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively (By similarity)
AS145_18295	ENOG4105D07	Signal peptide peptidase, SppA
AS145_18310	ENOG4105CAR	Terminase, large subunit
AS145_18480	ENOG4107R08	Integrase
AS145_18485	ENOG4105C5H	ABC transporter
AS145_18495	ENOG4105C7N	Xanthine uracil vitamin C permease
AS145_18500	ENOG41066UG	Regulatory DnaK co-chaperone. Direct interaction between DnaK and DjlA is needed for the induction of the wcaABCDE operon, involved in the synthesis of a colanic acid polysaccharide capsule, possibly through activation of the RcsB RcsC phosphotransfer signaling pathway. The colanic acid capsule may help the bacterium survive conditions outside the host (By similarity)
AS145_18505	ENOG4108S0S	Nucleotidyl transferase
AS145_18510	ENOG4105EHM	Aminoglycoside phosphotransferase
AS145_18515	ENOG4105E7H	involved in the assembly of LPS in the outer leaflet of the outer membrane. Determines N-hexane tolerance and is involved in outer membrane permeability. Essential for envelope biogenesis (By similarity)
AS145_18525	ENOG4105CEZ	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) (By similarity)
AS145_18530	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
AS145_18535	ENOG4105NWN	ApaG protein
AS145_18540	ENOG4105DDT	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP (By similarity)
AS145_18550	ENOG4105DEN	Luciferase family
AS145_18555	ENOG4108ESY	Metal dependent phosphohydrolase
AS145_18570	ENOG4105CEY	Amp-dependent synthetase and ligase
AS145_18575	ENOG4105DWD	nucleoside recognition domain protein
AS145_18580	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
AS145_18585	ENOG4105K46	50S ribosomal protein l27
AS145_18595	ENOG4105EAH	synthase
AS145_18605	ENOG4105EPW	hflc protein
AS145_18610	ENOG4107QJR	hflk protein
AS145_18615	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
AS145_18620	ENOG4105KW8	RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity)
AS145_18625	ENOG4105DKX	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity)
AS145_18630	ENOG4105DC6	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity)
AS145_18635	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
AS145_18640	ENOG4105K8N	protein family UPF0079, ATPase
AS145_18645	ENOG4105DR1	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)
AS145_18650	ENOG4105EH2	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity)
AS145_18670	ENOG4108JEI	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity)
AS145_18675	ENOG4108UMI	ABC transporter, permease
AS145_18680	ENOG4105D01	(LipO)protein
AS145_18685	ENOG4105MDZ	Transcriptional activator rfaH
AS145_18690	ENOG4108N3W	hemolysin secretion protein
AS145_18695	ENOG4105BZU	Histidine kinase
AS145_18700	ENOG4105BZU	Histidine kinase
AS145_18710	ENOG4105C4Q	deoxyguanosinetriphosphate triphosphohydrolase-like protein
AS145_18715	ENOG4105BZU	Histidine kinase
AS145_18735	ENOG4106173	Uncharacterized protein conserved in bacteria (DUF2057)
AS145_18740	ENOG4105EXG	Transcriptional regulator
AS145_18750	ENOG4107QWK	SAICAR synthetase
AS145_18755	ENOG4107EG0	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
AS145_18760	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
AS145_18765	ENOG4105RH4	Glycine cleavage system transcriptional repressor
AS145_18770	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
AS145_18775	ENOG4105XWI	UPF0304 protein
AS145_18780	ENOG4105PQ6	UPF0208 membrane protein
AS145_18785	ENOG4105C6H	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity)
AS145_18790	ENOG4105C6K	Malic enzyme
AS145_18795	ENOG4108ZP8	Acetolactate synthase small subunit
AS145_18800	ENOG4105C7K	acetolactate synthase
AS145_18810	ENOG4105YVM	Phosphoesterase, PA-phosphatase related
AS145_18820	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
AS145_18830	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
AS145_18835	ENOG4105MQS	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
AS145_18850	ENOG4105DP9	ABC transporter
AS145_18855	ENOG4106SMU	thiamine transporter membrane protein
AS145_18860	ENOG4107T0D	ABC, transporter
AS145_18865	ENOG4108IAB	Phoh family
AS145_18875	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
AS145_18905	ENOG4105BZK	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair (By similarity)
AS145_18910	ENOG4105D3G	Pseudouridine synthase
AS145_18920	ENOG4105BZU	Histidine kinase
AS145_18930	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
AS145_18935	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
AS145_18940	ENOG4107QI1	Mate efflux family protein
AS145_18945	ENOG4108YH1	overproduction of this protein in Escherichia coli inhibits the F plasmid-mediated exclusion of bacteriophage T7
AS145_18950	ENOG4108IJ0	Aspartate ammonia-lyase
AS145_18955	ENOG4105DS2	Anaerobic c4-dicarboxylate transporter
AS145_18965	ENOG4105EV4	Multidrug resistance protein mdtH
AS145_18985	ENOG4105D9U	N-acetyltransferase
AS145_18995	ENOG4105D9R	oxidoreductase
AS145_19005	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
AS145_19010	ENOG4105CSA	Coproporphyrinogen iii oxidase
AS145_19020	ENOG4105NAE	bifunctional deaminase-reductase domain protein
AS145_19030	ENOG4105DC1	bifunctional purine biosynthesis protein purh
AS145_19035	ENOG4105C12	Phosphoribosylglycinamide synthetase
AS145_19065	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
AS145_19070	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
AS145_19075	ENOG4105KTH	gatB Yqey
AS145_19080	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
AS145_19090	ENOG4108K5P	(LipO)protein
AS145_19095	ENOG4108UM1	dedA family
AS145_19100	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
AS145_19105	ENOG4105CV2	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates (By similarity)
AS145_19110	ENOG4106NZV	Responsible for synthesis of pseudouridine from uracil- 13 in transfer RNAs (By similarity)
AS145_19115	ENOG4108UH8	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (By similarity)
AS145_19120	ENOG4105CE5	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) (By similarity)
AS145_19125	ENOG4105XX3	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity)
AS145_19130	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
AS145_19135	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
AS145_19140	ENOG4105DXN	mazG family
AS145_19145	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
AS145_19150	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
AS145_19155	ENOG4105BZU	Histidine kinase
AS145_19160	ENOG4108W15	Protein of unknown function (DUF1456)
AS145_19165	ENOG4108VBV	N-Acetylmuramoyl-L-alanine amidase
AS145_19170	ENOG4105E98	transcriptional regulator DeoR family
AS145_19175	ENOG4105C6Q	that is required for full activity and stability of the Y subunit. Could have a chaperone-like function for the proper and stable folding of
AS145_19180	ENOG4105E70	isomerase
AS145_19185	ENOG4108RG5	PTS system N-acetylgalactosamine-specific transporter subunit IIB
AS145_19195	ENOG4105F3R	pts system mannose fructose sorbose family iid
AS145_19200	ENOG4108YTN	IIa component
AS145_19205	ENOG4105CE4	GlcNAc 6-P deacetylase
AS145_19210	ENOG4105D2N	Aldolase
AS145_19220	ENOG4105CSZ	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate (By similarity)
AS145_19225	ENOG41071DT	Involved in DNA repair and RecF pathway recombination (By similarity)
AS145_19240	ENOG4105C3F	Signal peptidase i
AS145_19245	ENOG4105C4S	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity)
AS145_19260	ENOG41069PW	sigma-e factor negative regulatory protein
AS145_19265	ENOG4105EMN	RNA polymerase sigma factor
AS145_19270	ENOG4108IYU	L-aspartate oxidase
AS145_19280	ENOG4105Y75	tpr repeat protein
AS145_19285	ENOG4106XY2	Folate-binding protein involved in regulating the level of ATP-DnaA and in the modification of some tRNAs. It is probably a key factor in regulatory networks that act via tRNA modification, such as initiation of chromosomal replication (By similarity)
AS145_19310	ENOG4105CSG	Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps (By similarity)
AS145_19320	ENOG4105CJP	fad dependent oxidoreductase
AS145_19325	ENOG4105D2N	Aldolase
AS145_19330	ENOG4105BZA	Phosphoglycerate kinase
AS145_19335	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
AS145_19340	ENOG4105DKQ	ROK family
AS145_19345	ENOG4105CFZ	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III (By similarity)
AS145_19350	ENOG4105E09	nadh pyrophosphatase
AS145_19355	ENOG4105C26	Dehydrogenase
AS145_19360	ENOG4106MWK	domain protein
AS145_19365	ENOG4105EYW	Ion transport protein
AS145_19370	ENOG4105C8Q	Methyl-accepting chemotaxis
AS145_19380	ENOG4105CE6	Adenylation and deadenylation of glutamate--ammonia ligase (By similarity)
AS145_19405	ENOG4108IYI	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine (By similarity)
AS145_19410	ENOG4105E5Q	amino acid AbC transporter
AS145_19415	ENOG4105E5Q	amino acid AbC transporter
AS145_19420	ENOG4105CDA	abc transporter atp-binding protein
AS145_19425	ENOG4105CT1	(ABC) transporter
AS145_19430	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
AS145_19435	ENOG4105DJY	efflux transporter, rnd family, mfp subunit
AS145_19440	ENOG4105E3W	Two component transcriptional regulator (Winged helix family
AS145_19445	ENOG4105E0F	Histidine kinase
AS145_19485	ENOG4105EA8	2-Nitropropane dioxygenase
AS145_19510	ENOG4105CA0	peroxidase
AS145_19515	ENOG4107V4F	S-adenosyl-l-methionine hydroxide adenosyltransferase
AS145_19535	ENOG4105C1J	atp-dependent rna helicase
AS145_19545	ENOG4107YH7	Beta-lactamase (EC 3.5.2.6)
AS145_19550	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
AS145_19555	ENOG4105DWY	Agmatine deiminase
AS145_19570	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
AS145_19575	ENOG4108MJ3	acetyltransferase
AS145_19600	ENOG4105BZU	Histidine kinase
AS145_19605	ENOG4105BZU	Histidine kinase
AS145_19615	ENOG4107R4Q	Functions as an ATPase. May play a role in metal insertion (metal-chelatase) or as a chaperone (By similarity)
AS145_19625	ENOG41080E2	ribosomal-protein-alanine acetyltransferase
AS145_19635	ENOG4108IQE	Amp-dependent synthetase and ligase
AS145_19645	ENOG4105D9M	gamma-glutamylcysteine synthetase
AS145_19655	ENOG4105W39	Membrane
AS145_19675	ENOG4105DP0	ferredoxin-NADP reductase
AS145_19680	ENOG4105K9Q	Binds to the 23S rRNA (By similarity)
AS145_19685	ENOG4105VH8	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity)
AS145_19690	ENOG4108ZDX	Binds together with S18 to 16S ribosomal RNA (By similarity)
AS145_19695	ENOG4105C56	H( )-stimulated, divalent metal cation uptake system (By similarity)
AS145_19725	ENOG4105C2N	RNA methyltransferase TrmH family group 3
AS145_19730	ENOG4105C40	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity)
AS145_19735	ENOG4106TD9	Diguanylate cyclase
AS145_19740	ENOG4106762	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD) (By similarity)
AS145_19750	ENOG4108YZA	Nitrogen regulatory protein pii
AS145_19755	ENOG4105C4K	Nad synthetase
AS145_19815	ENOG4105C48	Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) (By similarity)
AS145_19820	ENOG41090X3	Peptidyl-prolyl cis-trans isomerase
AS145_19825	ENOG4105M02	This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity)
AS145_19830	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
AS145_19835	ENOG4105DTN	riboflavin biosynthesis protein ribF
AS145_19840	ENOG4105CJR	Integral membrane protein (MviN
AS145_19845	ENOG4105KQV	Binds directly to 16S ribosomal RNA (By similarity)
AS145_19850	ENOG41080HT	Transcriptional regulator, arsr family
AS145_19855	ENOG41063Z6	transcriptional regulator, lysR family
AS145_19865	ENOG4105DRC	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity)
AS145_19870	ENOG4105C0V	Provides the sole de novo source of dTMP for DNA biosynthesis (By similarity)
AS145_19875	ENOG4105C3B	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity)
AS145_19880	ENOG4108HRM	phosphoenolpyruvate--protein phosphotransferase
AS145_19885	ENOG4105EJF	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity)
AS145_19890	ENOG4105IRT	Sequence-specific endonuclease that cleaves unmethylated GATC sequences. It is involved in DNA mismatch repair (By similarity)
AS145_19900	ENOG4108YY1	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity)
AS145_19905	ENOG4105D6X	Specifically methylates guanosine-37 in various tRNAs (By similarity)
AS145_19910	ENOG4108ZR6	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity)
AS145_19915	ENOG4105K5M	30s ribosomal protein S16
AS145_19920	ENOG4105CB9	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
AS145_19925	ENOG4106KVJ	cytochrome C assembly protein
AS145_19930	ENOG4108JU6	CBS domain protein
AS145_19940	ENOG4105CJJ	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity)
AS145_19945	ENOG4108UV7	flagellar protein motX
AS145_19950	ENOG4105C80	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
AS145_19955	ENOG4105DMR	ABC, transporter
AS145_19960	ENOG4105GBT	ABC transporter
AS145_19965	ENOG4106PMH	Extracellular solute-binding protein family 3
AS145_19970	ENOG4105E5Z	arginine transporter ATP-binding subunit
AS145_19975	ENOG410682Y	Regulates arginine biosynthesis genes (By similarity)
AS145_19980	ENOG4105EZR	dyp-type peroxidase family protein
AS145_19985	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
AS145_20000	ENOG4108YZA	Nitrogen regulatory protein pii
AS145_20005	ENOG4108YZN	class I peptide chain release factor
AS145_20015	ENOG4105D9N	nucleoside
AS145_20020	ENOG4105HEI	LysR family (Transcriptional regulator
AS145_20035	ENOG4105BZW	Glycerate kinase
AS145_20040	ENOG4107QQ0	gntp family
AS145_20045	ENOG4108IXP	Carbohydrate diacid transcriptional activator CdaR
AS145_20050	ENOG4105XTV	UPF0231 protein
AS145_20065	ENOG4107RHT	methyl-accepting chemotaxis sensory transducer with Pas Pac sensor
AS145_20070	ENOG4108QYW	Bacterial hemolysins are exotoxins that attack blood cell membranes and cause cell rupture. Beta-hemolysin is a phospholipase C with specific activity toward sphingomyelins. Has a high specificity for sphingomyelin, hydrolyzes lysophosphatidylcholine at a much lower rate, but has no activity towards phosphatidylcholine, phosphatidylethanolamine, or phosphatidylserine (By similarity)
AS145_20085	ENOG4105C1J	atp-dependent rna helicase
AS145_20095	ENOG4108V1J	Has antioxidant activity. Could remove peroxides or H(2)O(2) (By similarity)
AS145_20125	ENOG4105CGF	Aromatic amino acid aminotransferase
AS145_20140	ENOG41076CZ	activating enzyme
AS145_20145	ENOG4105G0K	glycine radical enzyme YjjI family
AS145_20165	ENOG4107RE3	peptidase, S41
AS145_20195	ENOG4108N3W	hemolysin secretion protein
AS145_20200	ENOG4108M1A	Chitin-binding protein
AS145_20205	ENOG4107R11	Transcriptional regulator
AS145_20210	ENOG4108IJ6	ABC transporter
AS145_20215	ENOG4105ECW	sulfate abc transporter
AS145_20220	ENOG4108I5D	sulfate abc transporter
AS145_20230	ENOG4105DE7	Sulfate ABC transporter periplasmic sulfate-binding protein
AS145_20235	ENOG4107PU6	Membrane
AS145_20240	ENOG4108UW5	maltose o-acetyltransferase
AS145_20265	ENOG4105CH7	arginosuccinase
AS145_20270	ENOG4105CDH	Citrulline--aspartate ligase
AS145_20280	ENOG4105CAS	nag kinase
AS145_20285	ENOG4105C0N	N-acetylglutamate semialdehyde dehydrogenase
AS145_20295	ENOG4105CCA	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle (By similarity)
AS145_20305	ENOG4105CFH	Aspartokinase
AS145_20310	ENOG4105C28	cystathionine
AS145_20315	ENOG4105GGQ	This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis (By similarity)
AS145_20320	ENOG41086D8	Transcriptional regulator
AS145_20325	ENOG4108Z7R	Chaperone CsaA
AS145_20330	ENOG4105C44	Serine transporter
AS145_20335	ENOG4108RNI	3'(2')5'-bisphosphate nucleotidase
AS145_20340	ENOG4107RK2	ADP-ribose diphosphatase NudE
AS145_20345	ENOG4107Y3D	HAD-superfamily hydrolase subfamily IA variant 3
AS145_20350	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
AS145_20355	ENOG4108UDW	Transcriptional regulator, luxr family
AS145_20395	ENOG4108VAU	general secretion pathway protein G
AS145_20400	ENOG4105D7Q	type ii secretion system
AS145_20405	ENOG4107QHF	type ii secretion system protein e
AS145_20410	ENOG4105GVR	general secretion pathway protein D
AS145_20420	ENOG4105VEJ	Heat shock protein
AS145_20425	ENOG4105F4C	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress (By similarity)
AS145_20430	ENOG4105DJ1	Phosphoenolpyruvate Carboxylase
AS145_20445	ENOG4105VXR	cytoplasmic protein
AS145_20450	ENOG4108R6G	acetyltransferase
AS145_20455	ENOG4108XTF	Outer Membrane Lipoprotein
AS145_20460	ENOG4107RNS	bifunctional 2',3'-cyclic nucleotide 2'-phosphodiesterase 3'-nucleotidase periplasmic
AS145_20465	ENOG4108ZUB	Lysine exporter protein (Lyse ygga)
AS145_20470	ENOG4105VJY	transcriptional regulator
AS145_20475	ENOG4105NNS	Autoinducer synthesis protein
AS145_20480	ENOG4105CXD	Specific inhibitor of chromosomal initiation of replication in vitro. Binds the three 13-mers in the origin (oriC) to block initiation of replication (By similarity)
AS145_20485	ENOG4108IEC	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction (By similarity)
AS145_20500	ENOG4105CTS	PTS system mannitol-specific
AS145_20505	ENOG4107SQ3	mannitol-1-phosphate 5-dehydrogenase
AS145_20510	ENOG4105E61	Mannitol repressor protein
AS145_20515	ENOG4105C3N	Participates in control of cell volume in low-osmolarity conditions (By similarity)
AS145_20540	ENOG4108UPT	UPF0178 protein
AS145_20555	ENOG4107K5X	Membrane-bound metal-dependent hydrolase
AS145_20560	ENOG4105D9N	nucleoside
AS145_20565	ENOG4105C1J	atp-dependent rna helicase
AS145_20590	ENOG4105EIS	1,4-dihydroxy-2-naphthoate octaprenyltransferase
AS145_20595	ENOG4105E4F	Isochorismate synthase
AS145_20600	ENOG4105C4A	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC) (By similarity)
AS145_20605	ENOG4107J5P	Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC). Is also able to catalyze the hydrolysis of the thioester bond in palmitoyl-CoA in vitro (By similarity)
AS145_20610	ENOG4108IPT	Naphthoate synthase
AS145_20615	ENOG4105DNI	Converts SHCHC to OSB (By similarity)
AS145_20620	ENOG4105CEY	Amp-dependent synthetase and ligase
AS145_20635	ENOG4108MDY	Fimbrial
AS145_20640	ENOG4108FZ9	Chaperone
AS145_20645	ENOG4106PG1	outer membrane usher protein
AS145_20655	ENOG4105HMV	Fimbrial protein
AS145_20665	ENOG4107MM9	BNR Asp-box repeat-containing protein
AS145_20670	ENOG4108UB4	uncharacterized protein ygjQ
AS145_20675	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
AS145_20685	ENOG4107IFA	Lipase (EC 3.1.1.3)
AS145_20705	ENOG4105KNR	Activates the small RNA gene sgrS under glucose- phosphate stress conditions as well as yfdZ. Represses its own transcription under both stress and non-stress conditions. Might act as a sensor of the intracellular accumulation of phosphoglucose by binding these molecules in its C-terminal solute-binding domain (By similarity)
AS145_20710	ENOG4108IQK	o-acetylhomoserine
AS145_20720	ENOG4108I6A	alcohol dehydrogenase
AS145_20735	ENOG4105DZW	Dipeptidase
AS145_20740	ENOG4105EMU	Dehydrogenase
AS145_20760	ENOG4105KT7	mgtC SapB transporter
AS145_20780	ENOG4105E0M	Sulfatase
AS145_20785	ENOG4108YXU	transcriptional regulator AsnC family
AS145_20795	ENOG4105CVG	Homoserine O-transsuccinylase
AS145_20800	ENOG4105E4Y	Endoribonuclease that initiates mRNA decay (By similarity)
AS145_20805	ENOG4108I62	cina-like protein
AS145_20820	ENOG4105CJ1	ABC, transporter
AS145_20835	ENOG410667J	hydrolase
AS145_20840	ENOG4108Z86	Glutamine amidotransferase
AS145_20850	ENOG4107RYR	Transcriptional regulator, Crp Fnr family
AS145_20860	ENOG4105DFC	had-superfamily hydrolase, subfamily ia, variant
AS145_20865	ENOG4108IYS	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
AS145_20875	ENOG4105E4Z	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan (By similarity)
AS145_20880	ENOG4105CU5	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity)
AS145_20885	ENOG4105XQ6	frataxin-like protein
AS145_20890	ENOG4106CJB	Phospholipase Carboxylesterase
AS145_20895	ENOG4107T0K	Adenylate cyclase
AS145_20900	ENOG4105D6W	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity)
AS145_20905	ENOG41076E6	Uroporphyrinogen-III Synthase
AS145_20910	ENOG4105ECF	c-methyltransferase
AS145_20925	ENOG4105CBT	Fructose-1,6-bisphosphatase
AS145_20940	ENOG4105E0K	tonB-dependent siderophore receptor
AS145_20965	ENOG4105KVH	Transcriptional regulator
AS145_20970	ENOG4105N0V	mono-oxygenase ydhR
AS145_20985	ENOG4108TPP	exopolysaccharide synthesis
AS145_20990	ENOG4105C44	Serine transporter
AS145_20995	ENOG4105BZU	Histidine kinase
AS145_21010	ENOG4108WEF	Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1B (PBP1b) (By similarity)
AS145_21020	ENOG4105D41	biosynthesis protein thiH
AS145_21025	ENOG4105CA8	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity)
AS145_21035	ENOG4105D06	uba thif-type nad fad binding protein
AS145_21040	ENOG4108UV6	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity)
AS145_21045	ENOG4105CBF	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction (By similarity)
AS145_21050	ENOG4107Y8H	Aerolysin toxin
AS145_21065	ENOG4105ETX	regulatoR
AS145_21075	ENOG4105CWM	branched-chain amino acid transport system II carrier protein
AS145_21080	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
AS145_21085	ENOG4105C3R	Methionine synthase
AS145_21090	ENOG4105EEQ	Na H antiporter
AS145_21115	ENOG41090ED	Protein with unknown function (DUF469)
AS145_21125	ENOG4105UYK	outer membrane protein a
AS145_21130	ENOG4106PG1	outer membrane usher protein
AS145_21135	ENOG4106P2F	Pfam:Pili_assembly_C
AS145_21180	ENOG4108HU6	Metal dependent phosphohydrolase
AS145_21190	ENOG4105CGZ	zinc metallopeptidase
AS145_21195	ENOG4105F0S	class B acid phosphatase
AS145_21210	ENOG4107SDU	Methyl-accepting chemotaxis
AS145_21215	ENOG4107MMM	Anti-sigma-factor antagonist
AS145_21220	ENOG4105QD0	anti-sigma regulatory factor serine threonine protein kinase
AS145_21225	ENOG4105BZU	Histidine kinase
AS145_21230	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
AS145_21240	ENOG4105CSH	Transporter
AS145_21255	ENOG4105E15	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
AS145_21260	ENOG4105C5Y	PTS System
AS145_21275	ENOG4108PSC	Represses the expression of the murPQ operon involved in the uptake and degradation of N-acetylmuramic acid (MurNAc). Binds to two adjacent inverted repeats within the operator region. MurNAc 6-phosphate, the substrate of MurQ, is the specific inducer that weakens binding of MurR to the operator (By similarity)
AS145_21280	ENOG4105D1U	peptidase U62 modulator of DNA gyrase
AS145_21295	ENOG4105QD6	exported protein
AS145_21300	ENOG4105C03	ribonuclease
AS145_21305	ENOG4108Z03	MAF-like protein
AS145_21310	ENOG4105VQ7	Rod shape-determining protein MreD
AS145_21315	ENOG4105N3I	Involved in formation and maintenance of cell shape (By similarity)
AS145_21320	ENOG4105DFF	Rod shape-determining protein mreb
AS145_21345	ENOG4106855	Competence protein
AS145_21365	ENOG4105D7Q	type ii secretion system
AS145_21370	ENOG4107QHF	type ii secretion system protein e
AS145_21380	ENOG4108WTW	DNA transposition protein
AS145_21385	ENOG4105GVR	general secretion pathway protein D
AS145_21415	ENOG41062P1	Diguanylate cyclase phosphodiesterase
AS145_21420	ENOG4107XTP	(EAL) domain protein
AS145_21425	ENOG4105EWV	Sodium calcium exchanger membrane region
AS145_21430	ENOG4105C84	Histidine ammonia-lyase
AS145_21435	ENOG4105CGP	Urocanate hydratase
AS145_21440	ENOG41088SP	formiminoglutamate hydrolase
AS145_21445	ENOG4105CI2	imidazolone-5-propionate hydrolase
AS145_21450	ENOG4105CZE	histidine utilization repressor
AS145_21455	ENOG41077A9	carbonic anhydrase
AS145_21465	ENOG4105CRP	Part of the ABC transporter FtsEX involved in
AS145_21470	ENOG4105CAK	Cell division ATP-binding protein ftsE
AS145_21475	ENOG4105CCP	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
AS145_21480	ENOG4106H78	methyltransferase
AS145_21495	ENOG4105EJ2	Transcriptional regulator
AS145_21505	ENOG4107RZC	phospholipase d
AS145_21510	ENOG4105E4C	Lytic transglycosylase catalytic
AS145_21520	ENOG4105WKS	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity)
AS145_21530	ENOG41076UM	multiple antibiotic resistance (MarC)-related protein
AS145_21535	ENOG4105VVZ	metal-binding protein
AS145_21550	ENOG4105JQN	Transcriptional regulator
AS145_21565	ENOG4107FS9	Membrane
AS145_21580	ENOG4105CUG	Oligopeptidase b
AS145_21595	ENOG4105EMU	Dehydrogenase
AS145_21600	ENOG4108W5M	transcriptional regulator
AS145_21605	ENOG4108K2R	Glutathione-regulated potassium-efflux system ancillary protein
AS145_21650	ENOG4108ZT0	50S ribosomal protein l17
AS145_21655	ENOG4105CTF	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
AS145_21660	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
AS145_21665	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
AS145_21670	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
AS145_21675	ENOG4105CGG	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity)
AS145_21680	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
AS145_21685	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
AS145_21690	ENOG4105K4C	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity)
AS145_21695	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
AS145_21700	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
AS145_21705	ENOG4105VBI	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
AS145_21710	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
AS145_21715	ENOG4105KAR	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity)
AS145_21720	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
AS145_21725	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
AS145_21730	ENOG41083MP	50s ribosomal protein l29
AS145_21735	ENOG4108R70	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity)
AS145_21740	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
AS145_21745	ENOG4105KAP	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity)
AS145_21750	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
AS145_21755	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
AS145_21760	ENOG41080KG	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
AS145_21765	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
AS145_21770	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
AS145_21775	ENOG4108Z10	Involved in the binding of tRNA to the ribosomes (By similarity)
AS145_21785	ENOG4105E0F	Histidine kinase
AS145_21790	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
AS145_21795	ENOG4108RRZ	Transcription elongation factor GreB
AS145_21800	ENOG4105BZM	domain protein
AS145_21820	ENOG4105D3C	The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters (By similarity)
AS145_21825	ENOG4105MJ2	Competence protein
AS145_21830	ENOG4107RUK	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins (By similarity)
AS145_21835	ENOG4105CSF	NADPH-dependent glycerol-3-phosphate dehydrogenase
AS145_21840	ENOG4105IX2	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA (By similarity)
AS145_21845	ENOG4107YZP	Rhodanese domain protein
AS145_21850	ENOG4105CJI	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
AS145_21855	ENOG41063SB	peptidase
AS145_21865	ENOG4105DIQ	Transcriptional regulator
AS145_21870	ENOG4108UHU	Aldolase
AS145_21875	ENOG4105C01	Dihydroxy-acid dehydratase
AS145_21880	ENOG4108Z67	carbohydrate kinase, thermoresistant glucokinase family
AS145_21885	ENOG4105C6Z	Gluconate
AS145_21890	ENOG4105JIM	Phosphatidylserine synthase
AS145_21895	ENOG4105CB5	ATP-dependent DNA helicase recG
AS145_21905	ENOG4105SUU	thioesterase domain
AS145_21915	ENOG4108YYA	Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine (By similarity)
AS145_21920	ENOG4107S2Z	UPF0761 membrane protein
AS145_21930	ENOG4105C5F	glutamine synthetase
AS145_21940	ENOG4105CUX	Signal transduction histidine kinase
AS145_21945	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
AS145_21950	ENOG4105EKD	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism (By similarity)
AS145_21955	ENOG4105D4P	Coproporphyrinogen iii oxidase
AS145_21960	ENOG4105XCT	Protein of unknown function (DUF2489)
AS145_21965	ENOG4105ZR3	A GTPase-activating protein (GAP) that modifies Der EngA GTPase function. May play a role in ribosome biogenesis (By similarity)
AS145_21975	ENOG4106RE7	Cytochrome
AS145_21980	ENOG4105WHM	Necessary for normal cell division and for the maintenance of normal septation (By similarity)
AS145_21985	ENOG4105SG3	Protein of unknown function (DUF1488)
AS145_21990	ENOG4105E2X	shikimate dehydrogenase
AS145_21995	ENOG4105DBS	Key enzyme in heme biosynthesis. Catalyzes the oxidative decarboxylation of propionic acid side chains of rings A and B of coproporphyrinogen III (By similarity)
AS145_22000	ENOG4105EK0	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
AS145_22010	ENOG4108WI1	Dna topoisomerase
AS145_22015	ENOG4108RPN	Protein smg homolog
AS145_22020	ENOG4105C79	DNA protecting protein DprA
AS145_22030	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
AS145_22035	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
AS145_22040	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
AS145_22045	ENOG4105C1A	potassium transporter peripheral membrane
AS145_22050	ENOG4105D37	Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA (By similarity)
AS145_22055	ENOG4105CGY	Dna recombination protein
AS145_22075	ENOG4108TFM	Kinase, PfkB family
AS145_22080	ENOG4105DCF	alanine dehydrogenase
AS145_22085	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
AS145_22100	ENOG4108JCI	Transcriptional regulator
AS145_22105	ENOG4105C26	Dehydrogenase
AS145_22115	ENOG4105FR1	rard protein
AS145_22120	ENOG4105ECQ	AraC Family Transcriptional Regulator
AS145_22130	ENOG4105C52	Atpase, p-type (Transporting), had superfamily, subfamily ic
AS145_22135	ENOG4105CUC	YeeE YedE family protein
AS145_22140	ENOG410829K	Lysine exporter protein (Lyse ygga)
AS145_22150	ENOG4108YH8	Covalently attaches a chromophore to Cys residue(s) of phycobiliproteins (By similarity)
AS145_22175	ENOG41061EV	selenium-binding protein YdfZ
AS145_22185	ENOG4105HEI	LysR family (Transcriptional regulator
AS145_22190	ENOG4108UK5	Transposase
AS145_22195	ENOG4105C4R	Atp-dependent dna helicase
AS145_22200	ENOG4105DIH	basic membrane
AS145_22205	ENOG4108JQ9	ABC transporter
AS145_22210	ENOG4105UIB	(ABC) transporter
AS145_22220	ENOG4105CC0	LysR family Transcriptional regulator
AS145_22240	ENOG4105E46	N-alpha,N-alpha,N-alpha-trimethyl-L-histidine metabolic process
AS145_22245	ENOG4105DHU	Bile acid
AS145_22250	ENOG4105E5D	amino acid
AS145_22255	ENOG4108Y51	tRNA-binding protein
AS145_22260	ENOG4105E5D	amino acid
AS145_22265	ENOG4105FK9	beta-D-galactosidase beta subunit
AS145_22270	ENOG4105CNT	hydrolase family 2
AS145_22275	ENOG4105CQ4	Transcriptional regulator
AS145_22310	ENOG4108Z0R	Transferase
AS145_22315	ENOG4105C2M	dna polymerase I
AS145_22320	ENOG4108556	Isoprenoid biosynthesis protein with amidotransferase-like domain
AS145_22325	ENOG41065UX	Non-essential, abundant cell division factor that is required for proper Z-ring formation. It is recruited early to the divisome by direct interaction with FtsZ, stimulating Z-ring assembly and thereby promoting cell division earlier in the cell cycle. Its recruitment to the Z-ring requires functional FtsA or ZipA (By similarity)
AS145_22335	ENOG4105D7W	serine acetyltransferase
AS145_22345	ENOG4105E3W	Two component transcriptional regulator (Winged helix family
AS145_22350	ENOG4105E0F	Histidine kinase
AS145_22355	ENOG4108UIQ	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity)
AS145_22360	ENOG4107R73	Mate efflux family protein
AS145_22375	ENOG4105DS7	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity)
AS145_22380	ENOG4105E55	glycerol-3-phosphate acyltransferase
AS145_22385	ENOG4105C4G	Synthesis of 3-octaprenyl-4-hydroxybenzoate (By similarity)
AS145_22390	ENOG4105VEI	Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4- hydroxybenzoate (4HB) for the ubiquinone pathway (By similarity)
AS145_22395	ENOG4105X6C	Flagellar basal body-associated protein FliL
AS145_22405	ENOG4105D3Z	quinone oxidoreductase, yhdh yhfp family
AS145_22410	ENOG4105DIQ	Transcriptional regulator
AS145_22430	ENOG4105D8A	3-Deoxy-D-manno-octulosonic-acid transferase
AS145_22435	ENOG4105XA0	heptosyltransferase ii
AS145_22440	ENOG4106WTF	Glycosyl transferase, family 2
AS145_22445	ENOG4105M5K	heptosyltransferase
AS145_22450	ENOG4108ZEF	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity)
AS145_22455	ENOG4108MJ5	VirK protein
AS145_22460	ENOG4105ERD	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity)
AS145_22470	ENOG4105W0E	50S ribosomal protein L33
AS145_22475	ENOG4105W5Q	DNA repair protein (RadC
AS145_22480	ENOG4105CJS	Phosphopantothenoylcysteine decarboxylase
AS145_22485	ENOG4108Z1K	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA (By similarity)
AS145_22490	ENOG4105EC0	Required for nucleoid occlusion (NO) phenomenon, which prevents Z-ring formation and cell division over the nucleoid. Acts as a DNA-associated cell division inhibitor that binds simultaneously chromosomal DNA and FtsZ, and disrupts the assembly of FtsZ polymers. SlmA-DNA-binding sequences (SBS) are dispersed on non-Ter regions of the chromosome, preventing FtsZ polymerization at these regions (By similarity)
AS145_22495	ENOG4105D64	Mechanosensitive ion channel
AS145_22505	ENOG4107QP8	phosphohexose isomerase
AS145_22510	ENOG4105C6M	Alpha-keto-beta-hydroxylacyl reductoisomerase
AS145_22515	ENOG4105EMY	transcriptional regulator
AS145_22530	ENOG4105CD5	CoA-binding domain protein
AS145_22555	ENOG4108RR8	protoporphyrinogen oxidase
AS145_22560	ENOG4105D37	Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA (By similarity)
AS145_22565	ENOG4108ZK7	protein family UPF0029, Impact, N-terminal protein
AS145_22570	ENOG4105D9Y	Splits dipeptides with a prolyl residue in the C- terminal position (By similarity)
AS145_22575	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
AS145_22580	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
AS145_22585	ENOG4105CHU	acetyl-coa acetyltransferase
AS145_22590	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
AS145_22595	ENOG4105E0F	Histidine kinase
AS145_22610	ENOG41082K8	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Interacts with IscS and stimulates its activity. Then, accepts a sulfur from IscS and transfers it in turn to TusD (By similarity)
AS145_22615	ENOG4105M4H	endoribonuclease L-psp
AS145_22620	ENOG4108ZG0	Ompa motb domain protein
AS145_22625	ENOG4105D3W	isochorismatase
AS145_22630	ENOG4108R3E	Dna-3-methyladenine glycosylase i
AS145_22635	ENOG4108HMW	glycyl-tRNA synthetase, alpha subunit
AS145_22640	ENOG4105C38	Glycyl-tRNA synthetase beta subunit
AS145_22655	ENOG4107RIQ	Sulfate adenylate transferase
AS145_22675	ENOG4105CIC	tryptophan-specific transport protein
AS145_22680	ENOG4105HEE	Binding Domain protein
AS145_22690	ENOG4108EQM	faD-dependent pyridine nucleotide-disulfide oxidoreductase
AS145_22695	ENOG4105CNW	domain protein
AS145_22700	ENOG4108JUA	Transcriptional regulator
AS145_22705	ENOG4105FDP	GntR family transcriptional regulator
AS145_22710	ENOG4105CI1	PTS System
AS145_22715	ENOG4105F8D	glycoside hydrolase family 4
AS145_22720	ENOG4105ETE	Transcriptional regulator (LacI family
AS145_22725	ENOG4105CP9	extracellular ligand-binding receptor
AS145_22730	ENOG4105C32	Amino acid ABC transporter (Permease)
AS145_22735	ENOG4105CF8	branched-chain amino acid ABC transporter, permease
AS145_22740	ENOG4105C0Z	ABC transporter
AS145_22745	ENOG4108IV0	ABC, transporter
AS145_22760	ENOG4105M78	Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide (By similarity)
AS145_22775	ENOG4105W0Z	cytoplasmic protein
AS145_22780	ENOG4107QK7	reductase
AS145_22785	ENOG4105D3H	Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol (By similarity)
AS145_22795	ENOG4105C4P	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity)
AS145_22800	ENOG4105K63	Thioredoxin
AS145_22805	ENOG4105C1J	atp-dependent rna helicase
AS145_22810	ENOG4105C9X	ppx gppa phosphatase
AS145_22825	ENOG4105FFN	Specifically methylates the guanosine in position 1516 of 16S rRNA (By similarity)
AS145_22830	ENOG4105BZU	Histidine kinase
AS145_22835	ENOG4105DGW	oligopeptidase A
AS145_22840	ENOG4105D52	delta-aminolevulinic acid dehydratase
AS145_22845	ENOG4105F8V	Hydrolase, tatD family
AS145_22850	ENOG4105DCX	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity)
AS145_22855	ENOG4105X8U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation (By similarity)
AS145_22860	ENOG4105WKS	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity)
AS145_22865	ENOG4105CNK	Required, probably indirectly, for the hydroxylation of 2-octaprenylphenol to 2-octaprenyl-6-hydroxy-phenol, the fourth step in ubiquinone biosynthesis (By similarity)
AS145_22870	ENOG4105JC1	sterol-binding domain protein
AS145_22880	ENOG4105WMR	Protein CrcB homolog
AS145_22885	ENOG4105DZC	cytosine deaminase
AS145_22925	ENOG410822N	TonB family
AS145_22930	ENOG4109015	Biopolymer transport protein exbD tolR
AS145_22950	ENOG4105VJY	transcriptional regulator
AS145_22955	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
AS145_22960	ENOG410804X	Transcriptional regulator
AS145_22965	ENOG4105E3W	Two component transcriptional regulator (Winged helix family
AS145_22970	ENOG4105EB3	Histidine kinase
AS145_22980	ENOG4105CT7	inner membrane cred family protein
AS145_22985	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
AS145_22990	ENOG4105KNM	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
AS145_22995	ENOG4105C4J	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity)
AS145_23000	ENOG4105J80	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity)
AS145_23005	ENOG4105CDG	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity)
AS145_23010	ENOG4107S15	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
AS145_23015	ENOG4107Z6K	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
AS145_23020	ENOG4105KY6	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
AS145_23025	ENOG4105EE4	it plays a direct role in the translocation of protons across the membrane (By similarity)
AS145_23035	ENOG4105FA0	parb-like partition protein
AS145_23040	ENOG4107QJE	Chromosome Partitioning Protein
AS145_23045	ENOG4105D28	Specifically methylates the N7 position of a guanine in 16S rRNA (By similarity)
AS145_23050	ENOG4107RE5	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity)
AS145_23055	ENOG4105QTB	Flavodoxin
AS145_23060	ENOG4105E0K	tonB-dependent siderophore receptor
AS145_23065	ENOG4105IBP	Cyclic peptide transporter
AS145_23070	ENOG4105E0A	ABC, transporter
AS145_23080	ENOG4105S6R	Iron-hydroxamate transporter permease subunit
AS145_23085	ENOG4105C1H	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity)
AS145_23090	ENOG4105DHW	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
AS145_23095	ENOG4105NVJ	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme (By similarity)
AS145_23100	ENOG4105VG0	50S ribosomal protein l34
AS145_23105	ENOG4105CDA	abc transporter atp-binding protein
AS145_23110	ENOG4105E5Q	amino acid AbC transporter
AS145_23115	ENOG4105EAB	amino acid AbC transporter
AS145_23170	ENOG4108QY5	Ferric enterobactin transport protein