locus-tag	class	description
G9455_00010	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
G9455_00015	COG0848	biopolymer transport protein
G9455_00020	COG0811	peptide transport
G9455_00025	COG0811	peptide transport
G9455_00035	COG2771	luxR family
G9455_00040	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
G9455_00045	COG1349	DNA-binding transcription factor activity
G9455_00050	COG0745	RESPONSE REGULATOR receiver
G9455_00055	COG2205	protein histidine kinase activity
G9455_00065	COG4452	Inner membrane protein CreD
G9455_00070	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
G9455_00075	COG0355	proton-transporting ATP synthase activity, rotational mechanism
G9455_00080	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
G9455_00085	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
G9455_00090	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
G9455_00095	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
G9455_00100	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
G9455_00110	COG0356	it plays a direct role in the translocation of protons across the membrane
G9455_00120	COG1475	DNA binding
G9455_00125	COG1192	Involved in chromosome partitioning
G9455_00130	COG0357	Ribosomal RNA small subunit methyltransferase G
G9455_00135	COG0445	tRNA wobble uridine modification
G9455_00140	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
G9455_00145	COG4774	siderophore transport
G9455_00150	COG4615	Cyclic peptide transporter
G9455_00155	COG1120	ATPase activity
G9455_00170	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
G9455_00175	COG0706	membrane insertase activity
G9455_00180	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
G9455_00185	COG0594	ribonuclease P activity
G9455_00190	COG0230	Belongs to the bacterial ribosomal protein bL34 family
G9455_00210	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
G9455_00215	COG0592	DNA-directed DNA polymerase activity
G9455_00235	COG2378	regulation of single-species biofilm formation
G9455_00240	COG0071	Belongs to the small heat shock protein (HSP20) family
G9455_00245	COG0071	Belongs to the small heat shock protein (HSP20) family
G9455_00250	COG3977	Valine--pyruvate aminotransferase
G9455_00265	COG2814	Major facilitator Superfamily
G9455_00270	COG0745	RESPONSE REGULATOR receiver
G9455_00275	COG2205	protein histidine kinase activity
G9455_00295	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
G9455_00300	COG4191	Histidine kinase
G9455_00300	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
G9455_00305	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
G9455_00310	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
G9455_00315	COG1309	transcriptional regulator
G9455_00345	COG0469	pyruvate kinase activity
G9455_00350	COG2271	Major facilitator Superfamily
G9455_00375	COG0561	phosphatase activity
G9455_00380	COG2267	carboxylic ester hydrolase activity
G9455_00390	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
G9455_00395	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
G9455_00400	COG1758	RNA polymerase activity
G9455_00415	COG0859	PFAM glycosyl transferase family 9
G9455_00420	COG3642	lipopolysaccharide core region biosynthetic process
G9455_00460	COG0589	response to stress
G9455_00465	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
G9455_00470	COG2199	diguanylate cyclase activity
G9455_00475	COG1528	Iron-storage protein
G9455_00480	COG2081	HI0933 family
G9455_00485	COG2223	nitrite transmembrane transporter activity
G9455_00505	COG3188	usher protein
G9455_00525	COG2205	protein histidine kinase activity
G9455_00525	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
G9455_00535	COG3275	phosphorelay sensor kinase activity
G9455_00540	COG3279	Response regulator of the LytR AlgR family
G9455_00545	COG2223	nitrite transmembrane transporter activity
G9455_00550	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
G9455_00555	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
G9455_00570	COG0583	DNA-binding transcription factor activity
G9455_00575	COG4206	TonB-dependent receptor
G9455_00580	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
G9455_00620	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
G9455_00685	COG2003	Belongs to the UPF0758 family
G9455_00730	COG3311	Transcriptional regulator
G9455_00750	COG2771	luxR family
G9455_00765	COG3501	Rhs element vgr protein
G9455_00810	COG1358	cellular component organization or biogenesis
G9455_00870	COG0582	viral genome integration into host DNA
G9455_00875	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
G9455_00880	COG2166	iron-sulfur cluster assembly
G9455_00885	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
G9455_00890	COG0210	DNA helicase
G9455_00900	COG3245	cytochrome
G9455_00905	COG1063	alcohol dehydrogenase
G9455_00910	COG0156	8-amino-7-oxononanoate synthase activity
G9455_00920	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
G9455_00935	COG3306	glycosyltransferase involved in LPS biosynthesis
G9455_00955	COG1561	YicC-like family, N-terminal region
G9455_00960	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
G9455_00965	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
G9455_00975	COG0789	Transcriptional regulator
G9455_00980	COG2203	Gaf domain
G9455_00980	COG5001	Diguanylate cyclase
G9455_00980	COG4251	negative regulation of phosphorylation
G9455_00980	COG3706	GGDEF domain
G9455_00985	COG3084	Protein conserved in bacteria
G9455_00995	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
G9455_01000	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
G9455_01005	COG3639	organic phosphonate transmembrane transporter activity
G9455_01010	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
G9455_01015	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
G9455_01025	COG1335	isochorismatase
G9455_01035	COG1683	Conserved Protein
G9455_01040	COG0204	Acyl-transferase
G9455_01045	COG0204	Acyl-transferase
G9455_01050	COG0606	chelatase, subunit chli
G9455_01060	COG3978	acetolactate synthase activity
G9455_01070	COG0129	dihydroxy-acid dehydratase activity
G9455_01090	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
G9455_01095	COG0254	rRNA binding
G9455_01100	COG0702	epimerase
G9455_01105	COG0281	malic enzyme
G9455_01115	COG2205	protein histidine kinase activity
G9455_01120	COG0745	RESPONSE REGULATOR receiver
G9455_01125	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
G9455_01140	COG0366	Alpha amylase catalytic
G9455_01155	COG0443	Heat shock 70 kDa protein
G9455_01160	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
G9455_01165	COG3045	CreA protein
G9455_01185	COG0174	glutamine synthetase
G9455_01205	COG3842	ATPase activity
G9455_01210	COG1176	ABC-type spermidine putrescine transport system, permease component I
G9455_01215	COG1177	transmembrane transport
G9455_01220	COG2258	MOSC domain
G9455_01235	COG2050	protein possibly involved in aromatic compounds catabolism
G9455_01240	COG0514	ATP-dependent DNA helicase (RecQ)
G9455_01250	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
G9455_01260	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
G9455_01265	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
G9455_01275	COG2239	Acts as a magnesium transporter
G9455_01280	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
G9455_01280	COG1648	precorrin-2 dehydrogenase activity
G9455_01285	COG2116	formate transmembrane transporter activity
G9455_01295	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
G9455_01310	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
G9455_01315	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
G9455_01335	COG1595	DNA-templated transcription, initiation
G9455_01340	COG3806	Anti-sigma factor
G9455_01345	COG1968	undecaprenyl-diphosphatase activity
G9455_01350	COG0667	Aldo Keto reductase
G9455_01355	COG2017	converts alpha-aldose to the beta-anomer
G9455_01360	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
G9455_01370	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
G9455_01375	COG1609	Transcriptional regulator
G9455_01380	COG3250	beta-galactosidase activity
G9455_01400	COG0840	transmembrane signaling receptor activity
G9455_01430	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
G9455_01435	COG1288	antiporter activity
G9455_01440	COG1438	arginine binding
G9455_01445	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
G9455_01450	COG0540	Belongs to the ATCase OTCase family
G9455_01470	COG0688	phosphatidylethanolamine metabolic process
G9455_01480	COG3040	lipid binding
G9455_01485	COG2207	Transcriptional regulator
G9455_01490	COG1979	alcohol dehydrogenase
G9455_01495	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
G9455_01500	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
G9455_01510	COG2964	Protein conserved in bacteria
G9455_01515	COG3681	Belongs to the UPF0597 family
G9455_01525	COG0446	pyridine nucleotide-disulphide oxidoreductase
G9455_01530	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
G9455_01535	COG0564	pseudouridine synthase activity
G9455_01545	COG0542	response to heat
G9455_01550	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
G9455_01555	COG2502	aspartate--ammonia ligase
G9455_01560	COG1522	sequence-specific DNA binding
G9455_01570	COG5413	integral membrane protein
G9455_01595	COG2205	protein histidine kinase activity
G9455_01605	COG2204	response regulator
G9455_01620	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
G9455_01635	COG0745	RESPONSE REGULATOR receiver
G9455_01640	COG2205	protein histidine kinase activity
G9455_01650	COG0243	molybdopterin cofactor binding
G9455_01655	COG3005	denitrification pathway
G9455_01660	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
G9455_01680	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
G9455_01685	COG0569	domain protein
G9455_01690	COG0812	UDP-N-acetylmuramate dehydrogenase activity
G9455_01715	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
G9455_01730	COG0250	Participates in transcription elongation, termination and antitermination
G9455_01735	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
G9455_01740	COG0081	regulation of translation
G9455_01745	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
G9455_01750	COG0222	ribosome binding
G9455_01755	COG0085	RNA polymerase activity
G9455_01760	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
G9455_01770	COG2964	Protein conserved in bacteria
G9455_01775	COG0251	oxidation-reduction process
G9455_01785	COG2923	Belongs to the DsrF TusC family
G9455_01790	COG2168	tRNA wobble position uridine thiolation
G9455_01795	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
G9455_01800	COG0049	tRNA binding
G9455_01805	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
G9455_01810	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
G9455_01815	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
G9455_01855	COG2252	PERMEase
G9455_01860	COG2376	Dihydroxyacetone kinase
G9455_01865	COG1461	Dihydroxyacetone kinase
G9455_01880	COG3284	Transcriptional regulator
G9455_01890	COG2957	Belongs to the agmatine deiminase family
G9455_01895	COG4221	oxidoreductase activity
G9455_01900	COG0628	permease
G9455_01905	COG0494	nUDIX hydrolase
G9455_01930	COG0753	catalase activity
G9455_01935	COG1247	-acetyltransferase
G9455_01955	COG2199	diguanylate cyclase activity
G9455_01955	COG2203	Gaf domain
G9455_01965	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
G9455_01975	COG1175	transmembrane transport
G9455_02000	COG0583	DNA-binding transcription factor activity
G9455_02010	COG1741	Belongs to the pirin family
G9455_02015	COG2259	Doxx family
G9455_02020	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
G9455_02025	COG1074	ATP-dependent DNA helicase activity
G9455_02030	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
G9455_02040	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
G9455_02045	COG0346	lactoylglutathione lyase activity
G9455_02075	COG0745	RESPONSE REGULATOR receiver
G9455_02080	COG2205	protein histidine kinase activity
G9455_02085	COG2203	Gaf domain
G9455_02085	COG3706	GGDEF domain
G9455_02085	COG4251	negative regulation of phosphorylation
G9455_02085	COG5001	Diguanylate cyclase
G9455_02090	COG4771	TonB-dependent receptor
G9455_02095	COG1278	Cold shock
G9455_02115	COG0629	single-stranded DNA binding
G9455_02120	COG2197	response regulator
G9455_02125	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
G9455_02135	COG3047	cAMP biosynthetic process
G9455_02140	COG0840	transmembrane signaling receptor activity
G9455_02165	COG3135	benzoate transporter
G9455_02170	COG1396	sequence-specific DNA binding
G9455_02200	COG2926	Belongs to the UPF0265 family
G9455_02210	COG3028	Belongs to the UPF0307 family
G9455_02215	COG0312	modulator of DNA gyrase
G9455_02220	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
G9455_02225	COG5007	Belongs to the BolA IbaG family
G9455_02235	COG2854	intermembrane phospholipid transfer
G9455_02240	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
G9455_02245	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
G9455_02250	COG1127	ABC transporter
G9455_02255	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
G9455_02255	COG0517	IMP dehydrogenase activity
G9455_02260	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
G9455_02265	COG3117	lipopolysaccharide transmembrane transporter activity
G9455_02270	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
G9455_02275	COG1137	ATPase activity
G9455_02280	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
G9455_02290	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
G9455_02295	COG1660	Displays ATPase and GTPase activities
G9455_02300	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
G9455_02305	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
G9455_02305	COG3711	transcriptional antiterminator
G9455_02320	COG3964	amidohydrolase
G9455_02350	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
G9455_02355	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
G9455_02365	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
G9455_02370	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
G9455_02375	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
G9455_02380	COG0723	plastoquinol--plastocyanin reductase activity
G9455_02385	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
G9455_02390	COG2857	Cytochrome c1
G9455_02395	COG0625	glutathione transferase activity
G9455_02400	COG2969	positive regulation of protein catabolic process
G9455_02405	COG2823	Periplasmic or secreted lipoprotein
G9455_02410	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
G9455_02415	COG0792	nuclease activity
G9455_02420	COG3107	peptidoglycan biosynthetic process
G9455_02425	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
G9455_02435	COG2001	Belongs to the MraZ family
G9455_02440	COG0275	rRNA processing
G9455_02445	COG3116	cell division
G9455_02450	COG0768	penicillin binding
G9455_02460	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
G9455_02465	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
G9455_02470	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
G9455_02475	COG0772	Belongs to the SEDS family
G9455_02480	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
G9455_02485	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
G9455_02490	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
G9455_02495	COG0849	cell division
G9455_02500	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
G9455_02505	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
G9455_02515	COG0653	protein targeting
G9455_02525	COG0494	nUDIX hydrolase
G9455_02530	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
G9455_02535	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
G9455_02550	COG1459	type II secretion system
G9455_02555	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
G9455_02580	COG2186	Transcriptional regulator
G9455_02585	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
G9455_02590	COG0508	dehydrogenase complex catalyzes the overall conversion of
G9455_02595	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
G9455_02600	COG3447	MASE1 domain protein
G9455_02600	COG5002	protein histidine kinase activity
G9455_02600	COG5001	Diguanylate cyclase
G9455_02610	COG0840	transmembrane signaling receptor activity
G9455_02615	COG0840	transmembrane signaling receptor activity
G9455_02620	COG1752	Esterase of the alpha-beta hydrolase superfamily
G9455_02625	COG1049	propionate catabolic process, 2-methylcitrate cycle
G9455_02640	COG1280	lysine exporter protein (LysE YggA)
G9455_02650	COG0523	cobalamin synthesis protein
G9455_02655	COG0477	Major facilitator Superfamily
G9455_02670	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
G9455_02675	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
G9455_02720	COG0784	Response regulator, receiver
G9455_02720	COG0835	chemotaxis
G9455_02725	COG1028	Short-chain dehydrogenase reductase Sdr
G9455_02730	COG1444	tRNA N-acetyltransferase activity
G9455_02755	COG1803	Methylglyoxal synthase
G9455_02770	COG0252	asparaginase activity
G9455_02790	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
G9455_02790	COG1263	PTS System
G9455_02795	COG0366	Alpha amylase catalytic
G9455_02800	COG0110	maltose O-acetyltransferase activity
G9455_02805	COG1522	sequence-specific DNA binding
G9455_02810	COG5006	permease, DMT superfamily
G9455_02820	COG1012	belongs to the aldehyde dehydrogenase family
G9455_02825	COG1177	transmembrane transport
G9455_02830	COG1176	ABC-type spermidine putrescine transport system, permease component I
G9455_02835	COG3842	ATPase activity
G9455_02840	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
G9455_02845	COG0583	DNA-binding transcription factor activity
G9455_02850	COG1757	Na H antiporter
G9455_02885	COG0297	glycogen (starch) synthase activity
G9455_02890	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
G9455_02895	COG2813	Specifically methylates the guanine in position
G9455_02900	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
G9455_02905	COG5001	Diguanylate cyclase
G9455_02905	COG4251	negative regulation of phosphorylation
G9455_02905	COG2203	Gaf domain
G9455_02905	COG3706	GGDEF domain
G9455_02915	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
G9455_02925	COG2995	paraquat-inducible protein a
G9455_02930	COG3008	intermembrane lipid transfer
G9455_02930	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
G9455_02935	COG3009	Protein conserved in bacteria
G9455_02950	COG3240	lipase activity
G9455_02955	COG3111	PFAM Bacterial OB fold (BOF) protein
G9455_02965	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
G9455_02970	COG1194	a g-specific adenine glycosylase
G9455_02980	COG3267	Type II secretory pathway component ExeA
G9455_02980	COG3409	Peptidoglycan-binding domain 1 protein
G9455_02985	COG0617	tRNA 3'-terminal CCA addition
G9455_03000	COG1346	cytolysis
G9455_03005	COG1380	Effector of murein hydrolase LrgA
G9455_03010	COG0583	DNA-binding transcription factor activity
G9455_03035	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
G9455_03040	COG0306	phosphate transporter
G9455_03045	COG1392	Phosphate transport regulator
G9455_03060	COG1560	Kdo2-lipid A biosynthetic process
G9455_03065	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
G9455_03065	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
G9455_03070	COG1538	Outer membrane efflux protein
G9455_03075	COG0494	nUDIX hydrolase
G9455_03080	COG3151	Protein conserved in bacteria
G9455_03090	COG3150	esterase
G9455_03095	COG1051	belongs to the nudix hydrolase family
G9455_03110	COG1566	PFAM secretion protein HlyD family protein
G9455_03115	COG1289	transmembrane transporter activity
G9455_03165	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
G9455_03190	COG0204	Acyl-transferase
G9455_03195	COG1842	Phage shock protein A
G9455_03210	COG2827	Endonuclease containing a URI domain
G9455_03220	COG2962	Rard protein
G9455_03225	COG1573	uracil-dna glycosylase
G9455_03230	COG0697	spore germination
G9455_03240	COG1108	ABC-type Mn2 Zn2 transport systems permease components
G9455_03245	COG1121	(ABC) transporter
G9455_03250	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
G9455_03270	COG0739	heme binding
G9455_03280	COG3068	Protein conserved in bacteria
G9455_03300	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
G9455_03305	COG0582	viral genome integration into host DNA
G9455_03340	COG1546	Belongs to the CinA family
G9455_03345	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
G9455_03355	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
G9455_03360	COG0527	aspartate kinase activity
G9455_03365	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
G9455_03400	COG1686	Belongs to the peptidase S11 family
G9455_03405	COG0586	Pfam SNARE associated Golgi protein
G9455_03410	COG1253	flavin adenine dinucleotide binding
G9455_03415	COG0525	valine-tRNA ligase activity
G9455_03420	COG2927	DNA polymerase III (CHI subunit)
G9455_03425	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
G9455_03430	COG0795	lipopolysaccharide-transporting ATPase activity
G9455_03435	COG0795	lipopolysaccharide-transporting ATPase activity
G9455_03450	COG0582	viral genome integration into host DNA
G9455_03465	COG3561	AntA/AntB antirepressor
G9455_03500	COG0004	ammonium transporteR
G9455_03505	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
G9455_03520	COG0084	hydrolase, TatD family'
G9455_03525	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
G9455_03535	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
G9455_03540	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
G9455_03545	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
G9455_03550	COG0813	purine-nucleoside phosphorylase activity
G9455_03555	COG5002	protein histidine kinase activity
G9455_03555	COG5001	Diguanylate cyclase
G9455_03555	COG3447	MASE1 domain protein
G9455_03565	COG0560	Phosphoserine phosphatase
G9455_03590	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
G9455_03595	COG0776	regulation of translation
G9455_03610	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
G9455_03615	COG0735	belongs to the Fur family
G9455_03640	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
G9455_03645	COG0513	Belongs to the DEAD box helicase family
G9455_03650	COG3022	response to hydroperoxide
G9455_03665	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
G9455_03670	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
G9455_03675	COG0762	integral membrane protein
G9455_03680	COG1872	DUF167
G9455_03695	COG4166	transmembrane transport
G9455_03705	COG0110	maltose O-acetyltransferase activity
G9455_03715	COG1024	Enoyl-CoA hydratase
G9455_03730	COG4221	oxidoreductase activity
G9455_03735	COG0442	prolyl-tRNA aminoacylation
G9455_03740	COG0840	transmembrane signaling receptor activity
G9455_03745	COG0632	four-way junction helicase activity
G9455_03750	COG2255	four-way junction helicase activity
G9455_03755	COG1271	oxidase subunit
G9455_03760	COG1294	oxidase, subunit
G9455_03765	COG4890	Cyd operon protein YbgT
G9455_03770	COG3790	cyd operon protein YbgE
G9455_03775	COG0824	Thioesterase
G9455_03780	COG0811	peptide transport
G9455_03795	COG0823	Involved in the tonB-independent uptake of proteins
G9455_03800	COG2885	chlorophyll binding
G9455_03805	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
G9455_03850	COG0840	transmembrane signaling receptor activity
G9455_03855	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
G9455_03860	COG0676	glucose-6-phosphate 1-epimerase activity
G9455_03865	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
G9455_03870	COG1640	4-alpha-glucanotransferase
G9455_03875	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
G9455_03895	COG1051	belongs to the nudix hydrolase family
G9455_03900	COG2130	NADP-dependent
G9455_03905	COG1764	response to oxidative stress
G9455_03910	COG1846	Transcriptional regulator
G9455_03945	COG0561	phosphatase activity
G9455_03960	COG0733	neurotransmitter:sodium symporter activity
G9455_03970	COG0733	neurotransmitter:sodium symporter activity
G9455_03995	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
G9455_04010	COG1794	racemase activity, acting on amino acids and derivatives
G9455_04025	COG2731	YhcH YjgK YiaL family protein
G9455_04035	COG0668	transmembrane transport
G9455_04045	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
G9455_04095	COG0583	DNA-binding transcription factor activity
G9455_04100	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
G9455_04110	COG0488	(ABC) transporter
G9455_04115	COG0517	IMP dehydrogenase activity
G9455_04115	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
G9455_04120	COG1585	Membrane protein implicated in regulation of membrane protease activity
G9455_04125	COG0330	HflC and HflK could
G9455_04130	COG1648	precorrin-2 dehydrogenase activity
G9455_04130	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
G9455_04135	COG0175	sulfate reduction
G9455_04140	COG2895	sulfate adenylyltransferase (ATP) activity
G9455_04145	COG3273	potassium ion transport
G9455_04145	COG0471	metal ion transport
G9455_04150	COG0529	Catalyzes the synthesis of activated sulfate
G9455_04175	COG0840	transmembrane signaling receptor activity
G9455_04195	COG1136	(ABC) transporter
G9455_04210	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
G9455_04225	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
G9455_04230	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
G9455_04235	COG0163	prenyltransferase activity
G9455_04250	COG1131	(ABC) transporter
G9455_04255	COG0842	Transport permease protein
G9455_04260	COG1775	2-hydroxyglutaryl-CoA dehydratase, D-component
G9455_04265	COG1924	4 iron, 4 sulfur cluster binding
G9455_04285	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
G9455_04290	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
G9455_04305	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
G9455_04310	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
G9455_04315	COG1489	DNA binding
G9455_04325	COG1643	Atp-dependent helicase
G9455_04330	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
G9455_04335	COG0346	lactoylglutathione lyase activity
G9455_04345	COG2076	Multidrug Resistance protein
G9455_04355	COG0784	Response regulator, receiver
G9455_04355	COG3437	response regulator, receiver
G9455_04365	COG0671	phosphoesterase, PA-phosphatase related
G9455_04380	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
G9455_04385	COG0038	chloride channel
G9455_04395	COG0316	Belongs to the HesB IscA family
G9455_04420	COG1280	lysine exporter protein (LysE YggA)
G9455_04425	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
G9455_04440	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
G9455_04470	COG0745	RESPONSE REGULATOR receiver
G9455_04475	COG3104	oligopeptide transport
G9455_04480	COG1210	Utp--glucose-1-phosphate uridylyltransferase
G9455_04485	COG1555	photosystem II stabilization
G9455_04495	COG2350	Protein conserved in bacteria
G9455_04500	COG2917	probably involved in intracellular septation
G9455_04505	COG0076	glutamate decarboxylase activity
G9455_04510	COG1272	protein, Hemolysin III
G9455_04515	COG0569	domain protein
G9455_04515	COG2985	domain, Protein
G9455_04530	COG0784	Response regulator, receiver
G9455_04530	COG0835	chemotaxis
G9455_04535	COG2755	lipolytic protein G-D-S-L family
G9455_04540	COG4181	ATPase activity
G9455_04545	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
G9455_04550	COG1090	epimerase
G9455_04555	COG2200	EAL domain
G9455_04560	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
G9455_04565	COG4935	Belongs to the peptidase S8 family
G9455_04565	COG2234	aminopeptidase activity
G9455_04570	COG0220	tRNA (guanine-N7-)-methyltransferase activity
G9455_04575	COG3171	Protein conserved in bacteria
G9455_04580	COG2066	Belongs to the glutaminase family
G9455_04585	COG2897	thiosulfate sulfurtransferase activity
G9455_04590	COG1404	Belongs to the peptidase S8 family
G9455_04600	COG1132	(ABC) transporter
G9455_04625	COG3076	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome
G9455_04630	COG3300	MHYT domain
G9455_04630	COG5001	Diguanylate cyclase
G9455_04650	COG4628	conserved protein (DUF2132)
G9455_04655	COG0688	phosphatidylethanolamine metabolic process
G9455_04660	COG1162	GTPase activity
G9455_04665	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
G9455_04695	COG1278	Cold shock
G9455_04705	COG0840	transmembrane signaling receptor activity
G9455_04710	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
G9455_04715	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
G9455_04720	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
G9455_04765	COG0848	biopolymer transport protein
G9455_04770	COG0811	peptide transport
G9455_04775	COG0811	peptide transport
G9455_04790	COG4174	ABC transporter (Permease)
G9455_04795	COG4239	(ABC) transporter, permease
G9455_04805	COG0444	Belongs to the ABC transporter superfamily
G9455_04810	COG4608	Belongs to the ABC transporter superfamily
G9455_04815	COG2195	Cleaves the N-terminal amino acid of tripeptides
G9455_04820	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
G9455_04840	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
G9455_04865	COG0243	molybdopterin cofactor binding
G9455_04880	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
G9455_04880	COG1116	anion transmembrane transporter activity
G9455_04885	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
G9455_04890	COG1116	anion transmembrane transporter activity
G9455_04895	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
G9455_04895	COG2146	nitrite reductase [NAD(P)H] activity
G9455_04900	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
G9455_04900	COG2146	nitrite reductase [NAD(P)H] activity
G9455_04905	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
G9455_04910	COG2313	pseudouridylate synthase activity
G9455_04920	COG1858	cytochrome C peroxidase
G9455_04955	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
G9455_04960	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
G9455_04985	COG2986	histidine ammonia-lyase
G9455_05010	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
G9455_05020	COG1028	Short-chain dehydrogenase reductase Sdr
G9455_05035	COG0521	Mo-molybdopterin cofactor biosynthetic process
G9455_05045	COG2966	Psort location CytoplasmicMembrane, score
G9455_05050	COG3610	response to peptide
G9455_05060	COG4175	Glycine betaine
G9455_05065	COG4176	ABC-type proline glycine betaine transport system permease component
G9455_05070	COG2113	Glycine betaine
G9455_05075	COG0175	sulfate reduction
G9455_05080	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
G9455_05085	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
G9455_05090	COG0384	phenazine biosynthesis protein PhzF
G9455_05095	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
G9455_05110	COG0786	glutamate:sodium symporter activity
G9455_05115	COG0252	asparaginase activity
G9455_05120	COG3139	Protein of unknown function (DUF1315)
G9455_05140	COG0616	signal peptide processing
G9455_05145	COG0446	pyridine nucleotide-disulphide oxidoreductase
G9455_05145	COG1902	pentaerythritol trinitrate reductase activity
G9455_05150	COG0778	Nitroreductase
G9455_05165	COG2264	protein methyltransferase activity
G9455_05170	COG0604	alcohol dehydrogenase
G9455_05175	COG0583	DNA-binding transcription factor activity
G9455_05180	COG2190	(PTS) system
G9455_05180	COG1263	PTS System
G9455_05180	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
G9455_05185	COG4145	pantothenate transmembrane transporter activity
G9455_05195	COG0439	Biotin carboxylase
G9455_05200	COG0511	ligase activity, forming carbon-carbon bonds
G9455_05205	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
G9455_05210	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
G9455_05220	COG5001	Diguanylate cyclase
G9455_05220	COG3300	MHYT domain
G9455_05240	COG3381	protein complex oligomerization
G9455_05255	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
G9455_05270	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
G9455_05275	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
G9455_05275	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
G9455_05295	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
G9455_05300	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
G9455_05305	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
G9455_05310	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
G9455_05315	COG4172	Belongs to the ABC transporter superfamily
G9455_05335	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
G9455_05340	COG0142	geranyltranstransferase activity
G9455_05345	COG1722	exodeoxyribonuclease VII activity
G9455_05350	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
G9455_05355	COG1360	Flagellar Motor Protein
G9455_05370	COG1534	Rna-binding protein
G9455_05375	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
G9455_05385	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
G9455_05390	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
G9455_05395	COG0149	triose-phosphate isomerase activity
G9455_05400	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
G9455_05415	COG0779	Required for maturation of 30S ribosomal subunits
G9455_05420	COG0195	Participates in both transcription termination and antitermination
G9455_05425	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
G9455_05430	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
G9455_05435	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
G9455_05440	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
G9455_05445	COG1185	polyribonucleotide nucleotidyltransferase activity
G9455_05460	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
G9455_05470	COG0114	fumarate hydratase activity
G9455_05480	COG1966	Carbon starvation protein
G9455_05485	COG3279	Response regulator of the LytR AlgR family
G9455_05555	COG0312	modulator of DNA gyrase
G9455_05560	COG0312	modulator of DNA gyrase
G9455_05570	COG4974	Belongs to the 'phage' integrase family
G9455_05575	COG1970	mechanosensitive ion channel activity
G9455_05580	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
G9455_05590	COG0789	Transcriptional regulator
G9455_05605	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
G9455_05610	COG3545	Serine hydrolase
G9455_05620	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
G9455_05625	COG0321	lipoyl(octanoyl) transferase activity
G9455_05630	COG2921	Belongs to the UPF0250 family
G9455_05635	COG1686	Belongs to the peptidase S11 family
G9455_05640	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
G9455_05645	COG2951	lytic endotransglycosylase activity
G9455_05650	COG0772	Belongs to the SEDS family
G9455_05655	COG0772	Belongs to the SEDS family
G9455_05660	COG0768	penicillin binding
G9455_05665	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
G9455_05670	COG0799	negative regulation of ribosome biogenesis
G9455_05675	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
G9455_05690	COG0495	leucyl-tRNA aminoacylation
G9455_05695	COG2888	peptidyl-tyrosine sulfation
G9455_05700	COG0815	Transfers the fatty acyl group on membrane lipoproteins
G9455_05705	COG4535	Mg2 and Co2 transporter CorC
G9455_05710	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
G9455_05715	COG1702	phosphate starvation-inducible protein PhoH
G9455_05720	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
G9455_05725	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
G9455_05730	COG1335	isochorismatase
G9455_05740	COG3706	GGDEF domain
G9455_05755	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
G9455_05765	COG3706	GGDEF domain
G9455_05775	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
G9455_05785	COG3647	Membrane
G9455_05790	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
G9455_05800	COG0516	GMP reductase activity
G9455_05810	COG0642	Histidine kinase
G9455_05815	COG0745	RESPONSE REGULATOR receiver
G9455_05850	COG3214	Protein conserved in bacteria
G9455_05875	COG3029	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
G9455_05880	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
G9455_05885	COG1053	succinate dehydrogenase
G9455_05895	COG0584	glycerophosphoryl diester phosphodiesterase
G9455_05900	COG3264	Mechanosensitive ion channel
G9455_05900	COG1511	domain protein
G9455_05910	COG0739	heme binding
G9455_05925	COG0583	DNA-binding transcription factor activity
G9455_05945	COG0583	DNA-binding transcription factor activity
G9455_05950	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
G9455_05980	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
G9455_05985	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
G9455_05995	COG0338	D12 class N6 adenine-specific DNA methyltransferase
G9455_06000	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
G9455_06010	COG0180	Tryptophanyl-tRNA synthetase
G9455_06025	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
G9455_06035	COG1012	belongs to the aldehyde dehydrogenase family
G9455_06045	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
G9455_06055	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
G9455_06055	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
G9455_06055	COG1013	pyruvate-flavodoxin oxidoreductase activity
G9455_06055	COG0674	pyruvate-flavodoxin oxidoreductase activity
G9455_06065	COG0366	Alpha amylase catalytic
G9455_06085	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
G9455_06095	COG0471	metal ion transport
G9455_06095	COG0490	domain, Protein
G9455_06130	COG0012	GTP binding
G9455_06135	COG0193	aminoacyl-tRNA hydrolase activity
G9455_06140	COG0737	Belongs to the 5'-nucleotidase family
G9455_06145	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
G9455_06155	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
G9455_06160	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
G9455_06165	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
G9455_06170	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
G9455_06175	COG2890	protein-(glutamine-N5) methyltransferase activity
G9455_06185	COG2912	Transglutaminase-like superfamily
G9455_06190	COG2877	3-deoxy-8-phosphooctulonate synthase activity
G9455_06195	COG1301	dicarboxylic acid transport
G9455_06205	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
G9455_06220	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
G9455_06225	COG1115	amino acid carrier protein
G9455_06240	COG0714	Associated with various cellular activities
G9455_06250	COG3104	oligopeptide transport
G9455_06255	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
G9455_06260	COG1678	Uncharacterized ACR, COG1678
G9455_06270	COG0189	ligase activity
G9455_06275	COG1385	rRNA (uridine-N3-)-methyltransferase activity
G9455_06285	COG3091	SprT-like family
G9455_06295	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
G9455_06300	COG3710	Transcriptional regulator
G9455_06340	COG2200	EAL domain
G9455_06360	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
G9455_06365	COG0739	heme binding
G9455_06370	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
G9455_06375	COG3408	Glycogen debranching enzyme
G9455_06375	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
G9455_06385	COG1881	PFAM PEBP family protein
G9455_06395	COG0583	DNA-binding transcription factor activity
G9455_06405	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
G9455_06415	COG0583	DNA-binding transcription factor activity
G9455_06420	COG1028	Short-chain dehydrogenase reductase Sdr
G9455_06425	COG0616	signal peptide processing
G9455_06430	COG3724	N-succinylarginine dihydrolase activity
G9455_06450	COG0840	transmembrane signaling receptor activity
G9455_06460	COG2971	BadF BadG BcrA BcrD
G9455_06470	COG4608	Belongs to the ABC transporter superfamily
G9455_06475	COG0444	Belongs to the ABC transporter superfamily
G9455_06480	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
G9455_06485	COG0601	transmembrane transport
G9455_06490	COG4166	transmembrane transport
G9455_06495	COG2205	protein histidine kinase activity
G9455_06495	COG0784	Response regulator, receiver
G9455_06525	COG3220	belongs to the UPF0276 family
G9455_06555	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
G9455_06560	COG1289	transmembrane transporter activity
G9455_06565	COG0303	'Molybdopterin
G9455_06570	COG0746	molybdenum cofactor guanylyltransferase activity
G9455_06580	COG4662	Binding-protein-dependent transport system inner membrane component
G9455_06590	COG2204	response regulator
G9455_06595	COG3852	Histidine kinase
G9455_06600	COG1910	domain protein
G9455_06605	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
G9455_06645	COG3383	formate dehydrogenase (NAD+) activity
G9455_06645	COG3383	formate dehydrogenase (NAD+) activity
G9455_06650	COG0437	4 iron, 4 sulfur cluster binding
G9455_06665	COG0281	malic enzyme
G9455_06685	COG2706	6-phosphogluconolactonase activity
G9455_06695	COG1196	nuclear chromosome segregation
G9455_06695	COG3264	Mechanosensitive ion channel
G9455_06700	COG0469	pyruvate kinase activity
G9455_06715	COG4651	solute:proton antiporter activity
G9455_06715	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
G9455_06725	COG2974	May be involved in recombination
G9455_06735	COG0420	3'-5' exonuclease activity
G9455_06740	COG0419	ATPase involved in DNA repair
G9455_06755	COG3038	cytochrome b561
G9455_06770	COG2190	(PTS) system
G9455_06780	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
G9455_06785	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
G9455_06790	COG0542	response to heat
G9455_06805	COG1720	tRNA m6t6A37 methyltransferase activity
G9455_06825	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
G9455_06830	COG4988	ABC transporter
G9455_06845	COG0745	RESPONSE REGULATOR receiver
G9455_06855	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
G9455_06870	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
G9455_06875	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
G9455_06885	COG0083	homoserine kinase activity
G9455_06890	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
G9455_06895	COG4319	ketosteroid isomerase
G9455_06910	COG0488	(ABC) transporter
G9455_06920	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
G9455_06930	COG0813	purine-nucleoside phosphorylase activity
G9455_06945	COG2205	protein histidine kinase activity
G9455_06945	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
G9455_06950	COG3384	dioxygenase
G9455_06960	COG1283	sodium-dependent phosphate transmembrane transporter activity
G9455_06970	COG0531	amino acid
G9455_06980	COG0531	amino acid
G9455_06995	COG1396	sequence-specific DNA binding
G9455_06995	COG1917	Cupin 2, conserved barrel domain protein
G9455_07000	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
G9455_07020	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
G9455_07025	COG2375	cellular response to nickel ion
G9455_07035	COG1136	(ABC) transporter
G9455_07035	COG0577	efflux transmembrane transporter activity
G9455_07040	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
G9455_07050	COG1227	inorganic diphosphatase activity
G9455_07055	COG0497	DNA recombination
G9455_07060	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
G9455_07065	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
G9455_07070	COG0443	Heat shock 70 kDa protein
G9455_07075	COG0484	heat shock protein binding
G9455_07105	COG1285	pathogenesis
G9455_07120	COG0640	Transcriptional regulator
G9455_07150	COG0095	Lipoate-protein ligase
G9455_07170	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
G9455_07175	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
G9455_07195	COG0708	Exodeoxyribonuclease III
G9455_07210	COG2211	Major facilitator Superfamily
G9455_07255	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
G9455_07260	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
G9455_07265	COG1845	cytochrome c oxidase, subunit III
G9455_07270	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
G9455_07275	COG0109	protoheme IX farnesyltransferase activity
G9455_07280	COG2814	Major facilitator Superfamily
G9455_07290	COG2205	protein histidine kinase activity
G9455_07290	COG0784	Response regulator, receiver
G9455_07290	COG2198	Histidine kinase
G9455_07295	COG1879	ABC-type sugar transport system periplasmic component
G9455_07305	COG0745	RESPONSE REGULATOR receiver
G9455_07320	COG3381	protein complex oligomerization
G9455_07360	COG2003	Belongs to the UPF0758 family
G9455_07395	COG0583	DNA-binding transcription factor activity
G9455_07410	COG0549	Belongs to the carbamate kinase family
G9455_07415	COG1304	FMN binding
G9455_07420	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
G9455_07425	COG1335	isochorismatase
G9455_07440	COG3311	Transcriptional regulator
G9455_07460	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
G9455_07500	COG0159	tryptophan synthase activity
G9455_07505	COG0133	tryptophan synthase activity
G9455_07510	COG0135	phosphoribosylanthranilate isomerase activity
G9455_07510	COG0134	indole-3-glycerol-phosphate synthase activity
G9455_07515	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
G9455_07520	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
G9455_07520	COG0512	Glutamine amidotransferase of anthranilate synthase
G9455_07525	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
G9455_07535	COG0009	L-threonylcarbamoyladenylate synthase
G9455_07545	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
G9455_07555	COG1946	Acyl-CoA thioesterase
G9455_07570	COG1309	transcriptional regulator
G9455_07575	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
G9455_07580	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
G9455_07590	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
G9455_07610	COG2244	polysaccharide biosynthetic process
G9455_07630	COG0110	maltose O-acetyltransferase activity
G9455_07645	COG0297	glycogen (starch) synthase activity
G9455_07650	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
G9455_07655	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
G9455_07665	COG0662	Cupin 2, conserved barrel domain protein
G9455_07665	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
G9455_07680	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
G9455_07685	COG1091	dTDP-4-dehydrorhamnose reductase activity
G9455_07690	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
G9455_07700	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
G9455_07730	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
G9455_07740	COG3132	Protein of unknown function, DUF480
G9455_07780	COG1278	Cold shock
G9455_07810	COG0697	spore germination
G9455_07815	COG1349	DNA-binding transcription factor activity
G9455_07820	COG1882	Formate acetyltransferase
G9455_07825	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
G9455_07830	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
G9455_07860	COG0622	Phosphoesterase
G9455_07875	COG1261	Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly
G9455_07880	COG0835	chemotaxis
G9455_07880	COG0784	Response regulator, receiver
G9455_07885	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
G9455_07890	COG1815	bacterial-type flagellum-dependent cell motility
G9455_07910	COG4787	bacterial-type flagellum-dependent cell motility
G9455_07920	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
G9455_07925	COG1706	bacterial-type flagellum-dependent cell motility
G9455_07930	COG3951	Flagellar rod assembly protein muramidase FlgJ
G9455_07930	COG1705	Flagellar rod assembly protein muramidase FlgJ
G9455_07935	COG1256	bacterial-type flagellum assembly
G9455_07945	COG2239	Acts as a magnesium transporter
G9455_07955	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
G9455_07960	COG2716	regulation of RNA biosynthetic process
G9455_07975	COG3852	Histidine kinase
G9455_07985	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
G9455_07990	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
G9455_07995	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
G9455_08000	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
G9455_08020	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
G9455_08035	COG0590	tRNA wobble adenosine to inosine editing
G9455_08040	COG0573	inorganic phosphate transmembrane transporter activity
G9455_08045	COG0581	inorganic phosphate transmembrane transporter activity
G9455_08055	COG0704	Plays a role in the regulation of phosphate uptake
G9455_08060	COG1253	flavin adenine dinucleotide binding
G9455_08075	COG0531	amino acid
G9455_08090	COG1126	abc transporter atp-binding protein
G9455_08095	COG0765	amino acid transport
G9455_08100	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
G9455_08110	COG2271	Major facilitator Superfamily
G9455_08125	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
G9455_08150	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
G9455_08155	COG0477	Major facilitator Superfamily
G9455_08160	COG0123	including yeast histone deacetylase and acetoin utilization protein
G9455_08170	COG1199	ATP-dependent helicase activity
G9455_08185	COG1448	Aminotransferase
G9455_08190	COG0433	COG0433 Predicted ATPase
G9455_08280	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
G9455_08290	COG1522	sequence-specific DNA binding
G9455_08330	COG5642	Protein of unknown function (DUF2384)
G9455_08345	COG2916	Histone family protein nucleoid-structuring protein H-NS
G9455_08390	COG1663	tetraacyldisaccharide 4'-kinase activity
G9455_08395	COG2835	tetraacyldisaccharide 4'-kinase activity
G9455_08400	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
G9455_08405	COG2197	response regulator
G9455_08410	COG0322	excinuclease ABC activity
G9455_08435	COG0582	viral genome integration into host DNA
G9455_08485	COG3962	Belongs to the TPP enzyme family
G9455_08495	COG0673	inositol 2-dehydrogenase activity
G9455_08500	COG1879	ABC-type sugar transport system periplasmic component
G9455_08510	COG1172	Belongs to the binding-protein-dependent transport system permease family
G9455_08515	COG0673	inositol 2-dehydrogenase activity
G9455_08520	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
G9455_08530	COG3718	enzyme involved in inositol metabolism
G9455_08615	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
G9455_08620	COG0437	4 iron, 4 sulfur cluster binding
G9455_08625	COG3301	Polysulphide reductase, NrfD
G9455_08630	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
G9455_08640	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
G9455_08645	COG0215	cysteine-tRNA ligase activity
G9455_08665	COG2203	Gaf domain
G9455_08665	COG2199	diguanylate cyclase activity
G9455_08695	COG2119	membrane
G9455_08700	COG0023	Translation Initiation Factor
G9455_08725	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
G9455_08740	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
G9455_08740	COG2205	protein histidine kinase activity
G9455_08750	COG4138	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system
G9455_08760	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
G9455_08765	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
G9455_08770	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
G9455_08775	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
G9455_08780	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
G9455_08790	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
G9455_08795	COG0505	Belongs to the CarA family
G9455_08800	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
G9455_08805	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
G9455_08835	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
G9455_08840	COG0513	Belongs to the DEAD box helicase family
G9455_08850	COG4104	PAAR repeat-containing protein
G9455_08865	COG0789	Transcriptional regulator
G9455_08880	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
G9455_08885	COG0765	amino acid transport
G9455_08895	COG0493	'glutamate synthase
G9455_08900	COG0069	glutamate synthase activity
G9455_08900	COG0067	glutamate synthase
G9455_08900	COG0070	glutamate synthase
G9455_08905	COG1242	4 iron, 4 sulfur cluster binding
G9455_08970	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
G9455_08975	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
G9455_08975	COG0574	Belongs to the PEP-utilizing enzyme family
G9455_09010	COG3038	cytochrome b561
G9455_09025	COG1464	Belongs to the NlpA lipoprotein family
G9455_09030	COG0671	phosphoesterase, PA-phosphatase related
G9455_09035	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
G9455_09040	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
G9455_09050	COG0101	tRNA pseudouridine synthase activity
G9455_09055	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
G9455_09060	COG0285	dihydrofolate synthase activity
G9455_09065	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
G9455_09070	COG2920	part of a sulfur-relay system
G9455_09075	COG1289	transmembrane transporter activity
G9455_09080	COG0670	Belongs to the BI1 family
G9455_09100	COG2194	sulfuric ester hydrolase activity
G9455_09105	COG0392	lysyltransferase activity
G9455_09105	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
G9455_09115	COG0840	transmembrane signaling receptor activity
G9455_09120	COG5001	Diguanylate cyclase
G9455_09125	COG0564	pseudouridine synthase activity
G9455_09140	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
G9455_09150	COG0625	glutathione transferase activity
G9455_09155	COG0625	glutathione transferase activity
G9455_09165	COG0367	asparagine synthase
G9455_09175	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
G9455_09175	COG4651	solute:proton antiporter activity
G9455_09180	COG0647	UMP catabolic process
G9455_09185	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
G9455_09190	COG1902	pentaerythritol trinitrate reductase activity
G9455_09195	COG1253	flavin adenine dinucleotide binding
G9455_09205	COG0277	FAD linked oxidase domain protein
G9455_09205	COG0247	lactate metabolic process
G9455_09215	COG2050	protein possibly involved in aromatic compounds catabolism
G9455_09225	COG2056	Na+-H+ antiporter family
G9455_09230	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
G9455_09245	COG0346	lactoylglutathione lyase activity
G9455_09250	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
G9455_09255	COG4660	Part of a membrane complex involved in electron transport
G9455_09260	COG4659	FMN binding
G9455_09265	COG4658	electron transport chain
G9455_09275	COG2878	Part of a membrane complex involved in electron transport
G9455_09280	COG4657	Part of a membrane complex involved in electron transport
G9455_09285	COG0697	spore germination
G9455_09300	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
G9455_09305	COG1288	antiporter activity
G9455_09310	COG0436	Aminotransferase
G9455_09320	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
G9455_09325	COG2027	D-alanyl-D-alanine carboxypeptidase
G9455_09330	COG1061	Type III restriction enzyme res subunit
G9455_09335	COG1566	PFAM secretion protein HlyD family protein
G9455_09345	COG1966	Carbon starvation protein
G9455_09350	COG3279	Response regulator of the LytR AlgR family
G9455_09355	COG3275	phosphorelay sensor kinase activity
G9455_09360	COG2199	diguanylate cyclase activity
G9455_09360	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
G9455_09365	COG1012	belongs to the aldehyde dehydrogenase family
G9455_09365	COG1454	alcohol dehydrogenase
G9455_09375	COG2095	MarC family integral membrane protein
G9455_09385	COG0601	transmembrane transport
G9455_09390	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
G9455_09410	COG0861	Integral membrane protein TerC family
G9455_09415	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
G9455_09425	COG1301	dicarboxylic acid transport
G9455_09440	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
G9455_09455	COG0537	adenosine 5'-monophosphoramidase activity
G9455_09490	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
G9455_09495	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
G9455_09505	COG2354	Protein conserved in bacteria
G9455_09520	COG2233	PERMEase
G9455_09525	COG3150	esterase
G9455_09530	COG1252	NADH dehydrogenase
G9455_09550	COG0393	Putative heavy-metal-binding
G9455_09560	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
G9455_09560	COG1648	precorrin-2 dehydrogenase activity
G9455_09580	COG4667	esterase of the alpha-beta hydrolase superfamily
G9455_09585	COG1619	proteins homologs of microcin C7 resistance protein MccF
G9455_09590	COG1368	sulfuric ester hydrolase activity
G9455_09600	COG0527	aspartate kinase activity
G9455_09605	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
G9455_09605	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
G9455_09610	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
G9455_09630	COG0596	Alpha beta hydrolase
G9455_09635	COG0346	lactoylglutathione lyase activity
G9455_09645	COG0583	DNA-binding transcription factor activity
G9455_09650	COG1620	l-lactate permease
G9455_09660	COG1139	Iron-sulfur cluster binding protein
G9455_09695	COG1136	(ABC) transporter
G9455_09705	COG2814	Major facilitator Superfamily
G9455_09725	COG0672	)-iron permease
G9455_09755	COG0659	secondary active sulfate transmembrane transporter activity
G9455_09790	COG4771	TonB-dependent receptor
G9455_09790	COG1629	transport
G9455_09820	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
G9455_09825	COG0840	transmembrane signaling receptor activity
G9455_09835	COG2201	protein-glutamate methylesterase activity
G9455_09845	COG0835	chemotaxis
G9455_09850	COG0840	transmembrane signaling receptor activity
G9455_09850	COG3290	protein histidine kinase activity
G9455_09855	COG2198	Histidine kinase
G9455_09855	COG0643	Histidine kinase
G9455_09865	COG0745	RESPONSE REGULATOR receiver
G9455_09870	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
G9455_09875	COG0437	4 iron, 4 sulfur cluster binding
G9455_09880	COG5557	Pfam Polysulphide reductase, NrfD
G9455_09885	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
G9455_09890	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
G9455_09895	COG1773	rubredoxin
G9455_09900	COG0747	negative chemotaxis
G9455_09905	COG0601	transmembrane transport
G9455_09910	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
G9455_09915	COG0444	Belongs to the ABC transporter superfamily
G9455_09920	COG3842	ATPase activity
G9455_09925	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
G9455_09930	COG0375	protein maturation
G9455_09935	COG0309	Hydrogenase expression formation protein (HypE)
G9455_09945	COG0298	carbon dioxide binding
G9455_09950	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
G9455_09960	COG1921	L-seryl-tRNASec selenium transferase activity
G9455_09970	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
G9455_09980	COG3260	NADH ubiquinone oxidoreductase 20
G9455_09985	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
G9455_09990	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
G9455_09990	COG3261	NADH dehydrogenase
G9455_09995	COG0650	Formate hydrogenlyase subunit 4
G9455_10000	COG0651	ATP synthesis coupled electron transport
G9455_10005	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
G9455_10010	COG3158	transport of potassium into the cell
G9455_10025	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
G9455_10050	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
G9455_10055	COG0326	Molecular chaperone. Has ATPase activity
G9455_10060	COG0563	adenylate kinase activity
G9455_10065	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
G9455_10075	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
G9455_10095	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
G9455_10115	COG1021	2,3-dihydroxybenzoate-AMP ligase
G9455_10120	COG1535	isochorismatase
G9455_10120	COG3433	isochorismatase activity
G9455_10125	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
G9455_10130	COG1028	Short-chain dehydrogenase reductase Sdr
G9455_10140	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
G9455_10145	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
G9455_10150	COG2977	Belongs to the P-Pant transferase superfamily
G9455_10155	COG1120	ATPase activity
G9455_10160	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
G9455_10165	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
G9455_10170	COG4771	TonB-dependent receptor
G9455_10210	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
G9455_10215	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
G9455_10220	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
G9455_10235	COG1570	exodeoxyribonuclease VII activity
G9455_10240	COG0697	spore germination
G9455_10260	COG3158	transport of potassium into the cell
G9455_10265	COG0516	GMP reductase activity
G9455_10265	COG0517	IMP dehydrogenase activity
G9455_10270	COG0518	GMP synthase (glutamine-hydrolyzing) activity
G9455_10270	COG0519	Catalyzes the synthesis of GMP from XMP
G9455_10275	COG0582	viral genome integration into host DNA
G9455_10330	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
G9455_10330	COG2169	Transcriptional regulator
G9455_10355	COG2062	phosphohistidine phosphatase, SixA
G9455_10365	COG0697	spore germination
G9455_10370	COG4166	transmembrane transport
G9455_10375	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
G9455_10380	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
G9455_10390	COG4591	ABC-type transport system involved in lipoprotein release permease component
G9455_10395	COG1136	(ABC) transporter
G9455_10400	COG4591	ABC-type transport system involved in lipoprotein release permease component
G9455_10405	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
G9455_10415	COG0544	peptidyl-prolyl cis-trans isomerase activity
G9455_10420	COG0740	serine-type endopeptidase activity
G9455_10425	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
G9455_10430	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
G9455_10435	COG0776	regulation of translation
G9455_10440	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
G9455_10445	COG0488	(ABC) transporter
G9455_10450	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
G9455_10455	COG3162	membrane
G9455_10470	COG1024	Enoyl-CoA hydratase
G9455_10505	COG1115	amino acid carrier protein
G9455_10520	COG1584	GPR1 FUN34 yaaH family protein
G9455_10555	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
G9455_10560	COG1960	acyl-CoA dehydrogenase activity
G9455_10570	COG1960	acyl-CoA dehydrogenase activity
G9455_10575	COG1024	Enoyl-CoA hydratase
G9455_10580	COG1024	Enoyl-CoA hydratase
G9455_10590	COG1028	Short-chain dehydrogenase reductase Sdr
G9455_10600	COG0730	response to heat
G9455_10625	COG5001	Diguanylate cyclase
G9455_10625	COG5002	protein histidine kinase activity
G9455_10645	COG2003	Belongs to the UPF0758 family
G9455_10660	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
G9455_10685	COG1073	alpha beta
G9455_10690	COG0823	Involved in the tonB-independent uptake of proteins
G9455_10690	COG1506	peptidase
G9455_10695	COG0702	epimerase
G9455_10700	COG0583	DNA-binding transcription factor activity
G9455_10705	COG0667	Aldo Keto reductase
G9455_10720	COG3706	GGDEF domain
G9455_10725	COG0583	DNA-binding transcription factor activity
G9455_10730	COG2723	6-phospho-beta-galactosidase activity
G9455_10735	COG5001	Diguanylate cyclase
G9455_10735	COG3300	MHYT domain
G9455_10745	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
G9455_10750	COG1028	Short-chain dehydrogenase reductase Sdr
G9455_10755	COG0583	DNA-binding transcription factor activity
G9455_10760	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
G9455_10765	COG0673	inositol 2-dehydrogenase activity
G9455_10770	COG0583	DNA-binding transcription factor activity
G9455_10780	COG1560	Kdo2-lipid A biosynthetic process
G9455_10785	COG1560	Kdo2-lipid A biosynthetic process
G9455_10810	COG0417	DNA replication proofreading
G9455_10840	COG0534	Mate efflux family protein
G9455_10850	COG0307	riboflavin synthase, alpha
G9455_10860	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
G9455_10865	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
G9455_10870	COG0697	spore germination
G9455_10875	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
G9455_10915	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
G9455_10920	COG3099	Belongs to the UPF0263 family
G9455_10925	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
G9455_10930	COG2894	cell division
G9455_10935	COG0850	regulation of cytokinetic process
G9455_10940	COG3100	YcgL domain-containing protein
G9455_10945	COG2951	lytic endotransglycosylase activity
G9455_10950	COG1760	l-serine dehydratase
G9455_10955	COG1760	l-serine dehydratase
G9455_10960	COG3123	guanosine phosphorylase activity
G9455_10980	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
G9455_11000	COG1595	DNA-templated transcription, initiation
G9455_11030	COG0714	Associated with various cellular activities
G9455_11035	COG0183	Belongs to the thiolase family
G9455_11040	COG1024	Enoyl-CoA hydratase
G9455_11040	COG1250	3-hydroxyacyl-CoA dehydrogenase
G9455_11090	COG4388	Caudovirus prohead serine protease
G9455_11100	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
G9455_11105	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
G9455_11110	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
G9455_11120	COG0549	Belongs to the carbamate kinase family
G9455_11125	COG0697	spore germination
G9455_11130	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
G9455_11130	COG3608	succinylglutamate desuccinylase aspartoacylase
G9455_11135	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
G9455_11140	COG2068	MobA-Related Protein
G9455_11145	COG0493	'glutamate synthase
G9455_11145	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
G9455_11150	COG0402	S-adenosylhomocysteine deaminase activity
G9455_11155	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
G9455_11160	COG1529	Aldehyde oxidase and xanthine dehydrogenase
G9455_11160	COG2080	2 iron, 2 sulfur cluster binding
G9455_11165	COG2233	PERMEase
G9455_11170	COG0402	S-adenosylhomocysteine deaminase activity
G9455_11175	COG2252	PERMEase
G9455_11180	COG1529	Aldehyde oxidase and xanthine dehydrogenase
G9455_11185	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
G9455_11190	COG2080	2 iron, 2 sulfur cluster binding
G9455_11200	COG3134	Outer membrane lipoprotein
G9455_11210	COG1288	antiporter activity
G9455_11215	COG0318	PFAM AMP-dependent synthetase and ligase
G9455_11220	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
G9455_11220	COG0140	phosphoribosyl-ATP diphosphatase activity
G9455_11225	COG0107	imidazoleglycerol-phosphate synthase activity
G9455_11230	COG2205	protein histidine kinase activity
G9455_11230	COG0784	Response regulator, receiver
G9455_11230	COG2198	Histidine kinase
G9455_11240	COG3437	response regulator, receiver
G9455_11245	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
G9455_11250	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
G9455_11255	COG0131	Imidazoleglycerol-phosphate dehydratase
G9455_11255	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
G9455_11260	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
G9455_11265	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
G9455_11270	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
G9455_11280	COG1199	ATP-dependent helicase activity
G9455_11285	COG1214	PFAM Peptidase M22, glycoprotease
G9455_11295	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
G9455_11295	COG2226	methyltransferase
G9455_11295	COG0596	Alpha beta hydrolase
G9455_11300	COG0318	PFAM AMP-dependent synthetase and ligase
G9455_11305	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
G9455_11435	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
G9455_11445	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
G9455_11450	COG2832	Protein of unknown function (DUF454)
G9455_11455	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
G9455_11465	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
G9455_11470	COG0582	viral genome integration into host DNA
G9455_11495	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
G9455_11595	COG0753	catalase activity
G9455_11620	COG3645	SOS response
G9455_11620	COG3646	Phage regulatory protein
G9455_11645	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
G9455_11650	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
G9455_11670	COG2916	Histone family protein nucleoid-structuring protein H-NS
G9455_11835	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
G9455_11835	COG0617	tRNA 3'-terminal CCA addition
G9455_11835	COG0517	IMP dehydrogenase activity
G9455_11840	COG1643	Atp-dependent helicase
G9455_11850	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
G9455_11860	COG3437	response regulator, receiver
G9455_11865	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
G9455_11870	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
G9455_11875	COG0709	Synthesizes selenophosphate from selenide and ATP
G9455_11890	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
G9455_11895	COG0840	transmembrane signaling receptor activity
G9455_11900	COG1254	Belongs to the acylphosphatase family
G9455_11905	COG0625	glutathione transferase activity
G9455_11910	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
G9455_11910	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
G9455_11915	COG0489	protein tyrosine kinase activity
G9455_11920	COG0572	uridine kinase
G9455_11925	COG0717	Belongs to the dCTP deaminase family
G9455_11930	COG0306	phosphate transporter
G9455_11935	COG1530	ribonuclease E activity
G9455_11940	COG0564	pseudouridine synthase activity
G9455_11950	COG0424	maF-like protein
G9455_11955	COG2814	Major facilitator Superfamily
G9455_11970	COG1399	metal-binding, possibly nucleic acid-binding protein
G9455_11975	COG0333	Belongs to the bacterial ribosomal protein bL32 family
G9455_11980	COG0416	fatty acid biosynthetic process
G9455_11985	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
G9455_11995	COG1028	Short-chain dehydrogenase reductase Sdr
G9455_12000	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
G9455_12010	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
G9455_12015	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
G9455_12020	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
G9455_12025	COG0470	DNA polymerase III
G9455_12030	COG0084	hydrolase, TatD family'
G9455_12050	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
G9455_12050	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
G9455_12055	COG3008	intermembrane lipid transfer
G9455_12060	COG2995	paraquat-inducible protein a
G9455_12070	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
G9455_12075	COG0372	Belongs to the citrate synthase family
G9455_12120	COG4221	oxidoreductase activity
G9455_12130	COG3141	response to X-ray
G9455_12140	COG1067	ATP-dependent peptidase activity
G9455_12145	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
G9455_12160	COG0488	(ABC) transporter
G9455_12170	COG0116	Belongs to the methyltransferase superfamily
G9455_12170	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
G9455_12180	COG0167	dihydroorotate dehydrogenase activity
G9455_12185	COG2902	Dehydrogenase
G9455_12195	COG0308	aminopeptidase N
G9455_12205	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
G9455_12210	COG1956	GAF domain-containing protein
G9455_12220	COG3278	Belongs to the heme-copper respiratory oxidase family
G9455_12235	COG2010	Cytochrome c
G9455_12260	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
G9455_12265	COG0589	response to stress
G9455_12270	COG0037	tRNA processing
G9455_12285	COG0625	glutathione transferase activity
G9455_12290	COG1869	D-ribose catabolic process
G9455_12295	COG1129	ABC transporter
G9455_12300	COG1172	Belongs to the binding-protein-dependent transport system permease family
G9455_12305	COG1879	ABC-type sugar transport system periplasmic component
G9455_12310	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
G9455_12315	COG1609	Transcriptional regulator
G9455_12350	COG0776	regulation of translation
G9455_12355	COG0072	phenylalanine-tRNA ligase activity
G9455_12355	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
G9455_12360	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
G9455_12365	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
G9455_12370	COG0291	Belongs to the bacterial ribosomal protein bL35 family
G9455_12375	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
G9455_12380	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
G9455_12405	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
G9455_12415	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
G9455_12420	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
G9455_12425	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
G9455_12430	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
G9455_12435	COG3313	Fe-S protein
G9455_12440	COG2942	2-epimerase
G9455_12445	COG3716	PTS system mannose fructose sorbose family IID component
G9455_12450	COG3715	PTS system
G9455_12455	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
G9455_12455	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
G9455_12470	COG1609	Transcriptional regulator
G9455_12475	COG2140	Oxalate decarboxylase
G9455_12480	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
G9455_12480	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
G9455_12480	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
G9455_12485	COG1105	Belongs to the carbohydrate kinase PfkB family
G9455_12490	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
G9455_12490	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
G9455_12495	COG1609	Transcriptional regulator
G9455_12500	COG0814	amino acid
G9455_12510	COG5654	RES domain protein
G9455_12520	COG0513	Belongs to the DEAD box helicase family
G9455_12530	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
G9455_12535	COG2890	protein-(glutamine-N5) methyltransferase activity
G9455_12540	COG2840	Smr protein MutS2
G9455_12550	COG3706	GGDEF domain
G9455_12555	COG0588	phosphoglycerate mutase activity
G9455_12580	COG2824	Alkylphosphonate utilization operon protein PhnA
G9455_12595	COG0384	phenazine biosynthesis protein PhzF
G9455_12610	COG0242	peptide deformylase activity
G9455_12630	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
G9455_12635	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
G9455_12645	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
G9455_12650	COG1434	Gram-negative-bacterium-type cell wall biogenesis
G9455_12660	COG0205	6-phosphofructokinase activity
G9455_12665	COG1473	amidohydrolase
G9455_12670	COG1011	Hydrolase
G9455_12675	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
G9455_12715	COG3593	DNA synthesis involved in DNA repair
G9455_12730	COG0583	DNA-binding transcription factor activity
G9455_12735	COG0730	response to heat
G9455_12755	COG1181	Belongs to the D-alanine--D-alanine ligase family
G9455_12765	COG0386	Belongs to the glutathione peroxidase family
G9455_12770	COG0513	Belongs to the DEAD box helicase family
G9455_12775	COG0456	acetyltransferase
G9455_12785	COG1742	UPF0060 membrane protein
G9455_12815	COG2329	Antibiotic biosynthesis monooxygenase
G9455_12820	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
G9455_12840	COG3243	poly(R)-hydroxyalkanoic acid synthase
G9455_12850	COG2501	S4 domain
G9455_12865	COG1132	(ABC) transporter
G9455_12870	COG1132	(ABC) transporter
G9455_12880	COG3118	belongs to the thioredoxin family
G9455_12890	COG0058	SHG alpha-glucan phosphorylase activity
G9455_12920	COG0814	amino acid
G9455_12925	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
G9455_12930	COG0514	ATP-dependent DNA helicase (RecQ)
G9455_12935	COG2766	serine protein kinase
G9455_12945	COG2719	SpoVR family
G9455_12950	COG2186	Transcriptional regulator
G9455_12955	COG3067	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
G9455_12960	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
G9455_12965	COG0586	Pfam SNARE associated Golgi protein
G9455_12975	COG0556	nucleotide-excision repair
G9455_12985	COG0569	domain protein
G9455_12985	COG2985	domain, Protein
G9455_12990	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
G9455_13010	COG4565	transcriptional regulatory protein
G9455_13015	COG3290	protein histidine kinase activity
G9455_13020	COG1846	Transcriptional regulator
G9455_13020	COG1940	carbohydrate kinase activity
G9455_13025	COG0840	transmembrane signaling receptor activity
G9455_13030	COG3012	SEC-C Motif Domain Protein
G9455_13035	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
G9455_13040	COG3075	Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses fumarate or nitrate as electron acceptor
G9455_13045	COG0247	lactate metabolic process
G9455_13065	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
G9455_13070	COG0437	4 iron, 4 sulfur cluster binding
G9455_13075	COG3301	Polysulphide reductase, NrfD
G9455_13080	COG1138	Cytochrome C-type biogenesis protein
G9455_13090	COG3088	subunit of a heme lyase
G9455_13090	COG4235	cytochrome complex assembly
G9455_13095	COG1051	belongs to the nudix hydrolase family
G9455_13105	COG3033	Beta-eliminating lyase
G9455_13115	COG3046	protein related to deoxyribodipyrimidine photolyase
G9455_13120	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
G9455_13145	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
G9455_13150	COG0583	DNA-binding transcription factor activity
G9455_13160	COG4774	siderophore transport
G9455_13165	COG4977	sequence-specific DNA binding
G9455_13175	COG0583	DNA-binding transcription factor activity
G9455_13180	COG2910	NAD(P)H-binding
G9455_13190	COG0626	cystathionine gamma-synthase activity
G9455_13195	COG0612	Peptidase, M16
G9455_13200	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
G9455_13210	COG1944	ATP diphosphatase activity
G9455_13215	COG2116	formate transmembrane transporter activity
G9455_13220	COG1882	Formate acetyltransferase
G9455_13225	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
G9455_13235	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
G9455_13245	COG1840	ABC-type Fe3 transport system, periplasmic component
G9455_13250	COG3842	ATPase activity
G9455_13260	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
G9455_13265	COG2983	Belongs to the UPF0260 family
G9455_13280	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
G9455_13285	COG0045	succinate-CoA ligase (ADP-forming) activity
G9455_13290	COG0508	dehydrogenase complex catalyzes the overall conversion of
G9455_13295	COG0567	Dehydrogenase, E1 component
G9455_13305	COG1053	succinate dehydrogenase
G9455_13310	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
G9455_13335	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
G9455_13340	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
G9455_13340	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
G9455_13350	COG3069	C4-dicarboxylate transmembrane transporter activity
G9455_13365	COG1451	nucleotide metabolic process
G9455_13380	COG0254	rRNA binding
G9455_13385	COG0257	Belongs to the bacterial ribosomal protein bL36 family
G9455_13395	COG0583	DNA-binding transcription factor activity
G9455_13405	COG1172	Belongs to the binding-protein-dependent transport system permease family
G9455_13415	COG1879	ABC-type sugar transport system periplasmic component
G9455_13420	COG1069	ribulokinase activity
G9455_13430	COG2160	L-arabinose isomerase activity
G9455_13435	COG2925	Exonuclease
G9455_13445	COG3345	alpha-galactosidase
G9455_13450	COG1380	Effector of murein hydrolase LrgA
G9455_13455	COG1346	cytolysis
G9455_13460	COG0295	cytidine deaminase activity
G9455_13465	COG1022	Amp-dependent synthetase and ligase
G9455_13480	COG0861	Integral membrane protein TerC family
G9455_13485	COG2885	chlorophyll binding
G9455_13490	COG2199	diguanylate cyclase activity
G9455_13510	COG2154	pterin-4-alpha-carbinolamine dehydratase
G9455_13520	COG3768	UPF0283 membrane protein
G9455_13525	COG3106	COG3106 Predicted ATPase
G9455_13540	COG1842	Phage shock protein A
G9455_13545	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
G9455_13555	COG4168	peptide transport system, permease
G9455_13560	COG4171	peptide transport system, permease
G9455_13570	COG4172	Belongs to the ABC transporter superfamily
G9455_13580	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
G9455_13585	COG1286	toxin biosynthetic process
G9455_13590	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
G9455_13595	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
G9455_13600	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
G9455_13605	COG0531	amino acid
G9455_13605	COG1674	ftsk spoiiie
G9455_13615	COG0686	Belongs to the AlaDH PNT family
G9455_13620	COG0492	ferredoxin-NADP+ reductase activity
G9455_13625	COG3706	GGDEF domain
G9455_13630	COG3134	Outer membrane lipoprotein
G9455_13635	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
G9455_13640	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
G9455_13645	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
G9455_13650	COG0542	response to heat
G9455_13655	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
G9455_13660	COG1278	Cold shock
G9455_13665	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
G9455_13705	COG3179	chitinase
G9455_13710	COG3501	Rhs element vgr protein
G9455_13815	COG3501	Rhs element vgr protein
G9455_13845	COG1435	thymidine kinase activity
G9455_13850	COG1757	Na H antiporter
G9455_13855	COG2916	Histone family protein nucleoid-structuring protein H-NS
G9455_13860	COG2096	Adenosyltransferase
G9455_13865	COG3530	Putative quorum-sensing-regulated virulence factor
G9455_13870	COG0602	queuosine metabolic process
G9455_13875	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
G9455_13895	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
G9455_13905	COG0776	regulation of translation
G9455_13910	COG0539	negative regulation of cytoplasmic translation
G9455_13915	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
G9455_13920	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
G9455_13930	COG0583	DNA-binding transcription factor activity
G9455_13950	COG0778	Nitroreductase
G9455_13955	COG3300	MHYT domain
G9455_13955	COG5001	Diguanylate cyclase
G9455_13965	COG0583	DNA-binding transcription factor activity
G9455_13970	COG3437	response regulator, receiver
G9455_13995	COG4989	oxidoreductase activity
G9455_14000	COG0724	RNA recognition motif
G9455_14020	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
G9455_14035	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
G9455_14040	COG1360	Flagellar Motor Protein
G9455_14045	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
G9455_14050	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
G9455_14055	COG0649	NAD binding
G9455_14055	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
G9455_14070	COG1034	ATP synthesis coupled electron transport
G9455_14075	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
G9455_14080	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
G9455_14085	COG0839	Belongs to the complex I subunit 6 family
G9455_14090	COG0713	ATP synthesis coupled electron transport
G9455_14100	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
G9455_14105	COG1007	ATP synthesis coupled electron transport
G9455_14115	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
G9455_14115	COG0047	phosphoribosylformylglycinamidine synthase activity
G9455_14120	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
G9455_14125	COG1645	bacterial-type flagellum-dependent swarming motility
G9455_14130	COG1160	GTP binding
G9455_14135	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
G9455_14140	COG2976	Protein conserved in bacteria
G9455_14145	COG0124	histidyl-tRNA synthetase
G9455_14150	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
G9455_14165	COG0820	rRNA (adenine-C2-)-methyltransferase activity
G9455_14170	COG0105	UTP biosynthetic process
G9455_14175	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
G9455_14185	COG0633	Ferredoxin
G9455_14190	COG0443	Heat shock 70 kDa protein
G9455_14195	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
G9455_14205	COG0822	iron-sulfur transferase activity
G9455_14210	COG1104	cysteine desulfurase activity
G9455_14230	COG3154	lipid carrier protein
G9455_14235	COG0826	peptidase U32
G9455_14240	COG0826	peptidase U32
G9455_14255	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
G9455_14260	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
G9455_14265	COG1862	Preprotein translocase
G9455_14270	COG0343	queuine tRNA-ribosyltransferase activity
G9455_14275	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
G9455_14280	COG0517	IMP dehydrogenase activity
G9455_14290	COG3634	alkyl hydroperoxide reductase activity
G9455_14310	COG1393	Belongs to the ArsC family
G9455_14315	COG0798	PFAM Bile acid sodium symporter
G9455_14320	COG0640	Transcriptional regulator
G9455_14325	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
G9455_14325	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
G9455_14330	COG0509	glycine decarboxylation via glycine cleavage system
G9455_14335	COG0404	The glycine cleavage system catalyzes the degradation of glycine
G9455_14340	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
G9455_14345	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
G9455_14365	COG2814	Major facilitator Superfamily
G9455_14370	COG0625	glutathione transferase activity
G9455_14380	COG0483	inositol monophosphate 1-phosphatase activity
G9455_14400	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
G9455_14415	COG1086	Polysaccharide biosynthesis protein
G9455_14435	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
G9455_14445	COG2089	acid synthase
G9455_14515	COG0301	tRNA thio-modification
G9455_14515	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
G9455_14525	COG4953	penicillin-binding protein 1C
G9455_14530	COG2373	Large extracellular alpha-helical protein
G9455_14535	COG1473	amidohydrolase
G9455_14540	COG0628	permease
G9455_14545	COG1538	Outer membrane efflux protein
G9455_14565	COG0446	pyridine nucleotide-disulphide oxidoreductase
G9455_14575	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
G9455_14595	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
G9455_14605	COG2431	L-lysine efflux transmembrane transporter activity
G9455_14610	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
G9455_14615	COG3124	Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP
G9455_14630	COG1393	Belongs to the ArsC family
G9455_14640	COG4783	chaperone-mediated protein folding
G9455_14645	COG0425	Belongs to the sulfur carrier protein TusA family
G9455_14670	COG3842	ATPase activity
G9455_14675	COG3833	ABC-type maltose transport systems, permease component
G9455_14680	COG1175	transmembrane transport
G9455_14690	COG3081	Nucleoid-associated protein
G9455_14695	COG3082	Protein of unknown function (DUF1414)
G9455_14700	COG3083	sulfuric ester hydrolase activity
G9455_14705	COG4771	TonB-dependent receptor
G9455_14710	COG1770	oligopeptidase
G9455_14730	COG4574	serine-type endopeptidase inhibitor activity
G9455_14735	COG3085	chromosome segregation
G9455_14740	COG0583	DNA-binding transcription factor activity
G9455_14745	COG0287	Prephenate dehydrogenase
G9455_14745	COG1605	Chorismate mutase
G9455_14750	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
G9455_14755	COG0584	glycerophosphoryl diester phosphodiesterase
G9455_14770	COG1349	DNA-binding transcription factor activity
G9455_14775	COG2271	Major facilitator Superfamily
G9455_14780	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
G9455_14785	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
G9455_14790	COG0583	DNA-binding transcription factor activity
G9455_14810	COG0656	L-ascorbic acid biosynthetic process
G9455_14815	COG2814	Major facilitator Superfamily
G9455_14825	COG1294	oxidase, subunit
G9455_14835	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
G9455_14845	COG2979	Protein of unknown function (DUF533)
G9455_14870	COG2271	Major facilitator Superfamily
G9455_14875	COG0583	DNA-binding transcription factor activity
G9455_14885	COG2807	transmembrane transport
G9455_14890	COG1187	pseudouridine synthase activity
G9455_14915	COG1061	Type III restriction enzyme res subunit
G9455_14925	COG2964	Protein conserved in bacteria
G9455_14930	COG3681	Belongs to the UPF0597 family
G9455_14940	COG0814	amino acid
G9455_14960	COG1166	arginine decarboxylase activity
G9455_14965	COG2195	Cleaves the N-terminal amino acid of tripeptides
G9455_14995	COG0583	DNA-binding transcription factor activity
G9455_15005	COG2759	Belongs to the formate--tetrahydrofolate ligase family
G9455_15010	COG0840	transmembrane signaling receptor activity
G9455_15015	COG0302	gtp cyclohydrolase
G9455_15025	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
G9455_15030	COG2267	carboxylic ester hydrolase activity
G9455_15035	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
G9455_15050	COG0314	molybdopterin synthase activity
G9455_15055	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
G9455_15060	COG0315	cyclic pyranopterin monophosphate synthase activity
G9455_15065	COG0521	Mo-molybdopterin cofactor biosynthetic process
G9455_15070	COG3005	denitrification pathway
G9455_15080	COG0348	domain, Protein
G9455_15085	COG0437	4 iron, 4 sulfur cluster binding
G9455_15090	COG0243	molybdopterin cofactor binding
G9455_15100	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
G9455_15100	COG1149	4fe-4S ferredoxin, iron-sulfur binding domain protein
G9455_15105	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
G9455_15110	COG3850	Histidine kinase
G9455_15115	COG2197	response regulator
G9455_15145	COG0121	glutamine amidotransferase
G9455_15150	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
G9455_15155	COG1960	acyl-CoA dehydrogenase activity
G9455_15160	COG3437	response regulator, receiver
G9455_15160	COG0784	Response regulator, receiver
G9455_15175	COG0328	RNA-DNA hybrid ribonuclease activity
G9455_15180	COG2226	methyltransferase
G9455_15185	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
G9455_15190	COG0741	lytic transglycosylase activity
G9455_15190	COG1388	LysM domain
G9455_15195	COG3021	interspecies interaction between organisms
G9455_15205	COG1607	acyl-coa hydrolase
G9455_15220	COG0741	lytic transglycosylase activity
G9455_15230	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
G9455_15255	COG0729	surface antigen
G9455_15265	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
G9455_15270	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
G9455_15280	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
G9455_15290	COG4134	Bacterial extracellular solute-binding protein
G9455_15300	COG4136	ATPase activity
G9455_15305	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
G9455_15310	COG2951	lytic endotransglycosylase activity
G9455_15315	COG1846	Transcriptional regulator
G9455_15325	COG0033	Phosphoglucomutase
G9455_15330	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
G9455_15335	COG0596	Alpha beta hydrolase
G9455_15350	COG0716	FMN binding
G9455_15360	COG0735	belongs to the Fur family
G9455_15365	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
G9455_15380	COG1263	PTS System
G9455_15380	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
G9455_15380	COG2190	(PTS) system
G9455_15385	COG0363	glucosamine-6-phosphate deaminase activity
G9455_15390	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
G9455_15395	COG1940	carbohydrate kinase activity
G9455_15395	COG1846	Transcriptional regulator
G9455_15400	COG2194	sulfuric ester hydrolase activity
G9455_15405	COG0217	transcriptional regulatory protein
G9455_15410	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
G9455_15420	COG1801	Protein of unknown function DUF72
G9455_15425	COG4106	trans-aconitate 2-methyltransferase activity
G9455_15430	COG0500	methyltransferase
G9455_15450	COG0450	alkyl hydroperoxide reductase
G9455_15455	COG0583	DNA-binding transcription factor activity
G9455_15465	COG0791	NLP P60 protein
G9455_15480	COG1309	transcriptional regulator
G9455_15520	COG0534	Mate efflux family protein
G9455_15540	COG2366	antibiotic biosynthetic process
G9455_15545	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
G9455_15545	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
G9455_15545	COG1013	pyruvate-flavodoxin oxidoreductase activity
G9455_15545	COG0674	pyruvate-flavodoxin oxidoreductase activity
G9455_15555	COG0633	Ferredoxin
G9455_15555	COG0633	Ferredoxin
G9455_15555	COG3217	Mosc domain protein beta barrel domain protein
G9455_15555	COG3217	Mosc domain protein beta barrel domain protein
G9455_15565	COG0501	Belongs to the peptidase M48B family
G9455_15570	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
G9455_15575	COG2226	methyltransferase
G9455_15575	COG1073	alpha beta
G9455_15580	COG0156	8-amino-7-oxononanoate synthase activity
G9455_15585	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
G9455_15605	COG0017	Asparaginyl-tRNA synthetase
G9455_15610	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
G9455_15625	COG3069	C4-dicarboxylate transmembrane transporter activity
G9455_15635	COG0583	DNA-binding transcription factor activity
G9455_15640	COG1393	Belongs to the ArsC family
G9455_15645	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
G9455_15650	COG1876	peptidase activity
G9455_15660	COG3263	regulation of cellular component size
G9455_15680	COG1280	lysine exporter protein (LysE YggA)
G9455_15705	COG1957	nucleoside hydrolase
G9455_15710	COG0564	pseudouridine synthase activity
G9455_15720	COG1454	alcohol dehydrogenase
G9455_15770	COG4964	Belongs to the GSP D family
G9455_15805	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
G9455_15810	COG0702	epimerase
G9455_15820	COG2867	negative regulation of translational initiation
G9455_15825	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
G9455_15910	COG4397	Mu-like prophage major head subunit gpT
G9455_15915	COG4388	Caudovirus prohead serine protease
G9455_15935	COG4383	Mu-like prophage protein gp29
G9455_15940	COG4373	Mu-like prophage FluMu protein gp28
G9455_15950	COG0640	Transcriptional regulator
G9455_15990	COG5566	PFAM Mor transcription activator
G9455_16100	COG0583	DNA-binding transcription factor activity
G9455_16105	COG2610	gluconate transmembrane transporter activity
G9455_16110	COG3048	D-serine ammonia-lyase activity
G9455_16120	COG0538	isocitrate dehydrogenase activity
G9455_16125	COG2207	Transcriptional regulator
G9455_16145	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
G9455_16155	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
G9455_16160	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
G9455_16160	COG1263	PTS System
G9455_16165	COG1609	Transcriptional regulator
G9455_16180	COG0456	acetyltransferase
G9455_16200	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
G9455_16200	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
G9455_16200	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
G9455_16210	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
G9455_16220	COG1187	pseudouridine synthase activity
G9455_16230	COG0482	sulfurtransferase activity
G9455_16235	COG2915	High frequency lysogenization protein hflD homolog
G9455_16240	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
G9455_16245	COG2850	peptidyl-arginine hydroxylation
G9455_16255	COG3153	acetyltransferase
G9455_16265	COG0625	glutathione transferase activity
G9455_16270	COG0259	pyridoxamine-phosphate oxidase activity
G9455_16285	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
G9455_16285	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
G9455_16290	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
G9455_16305	COG4235	cytochrome complex assembly
G9455_16305	COG3088	subunit of a heme lyase
G9455_16310	COG4235	cytochrome complex assembly
G9455_16310	COG3088	subunit of a heme lyase
G9455_16315	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
G9455_16320	COG1138	Cytochrome C-type biogenesis protein
G9455_16325	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
G9455_16330	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
G9455_16335	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
G9455_16340	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
G9455_16355	COG0835	chemotaxis
G9455_16365	COG1192	Involved in chromosome partitioning
G9455_16370	COG1360	Flagellar Motor Protein
G9455_16375	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
G9455_16380	COG2201	protein-glutamate methylesterase activity
G9455_16385	COG2198	Histidine kinase
G9455_16385	COG0784	Response regulator, receiver
G9455_16385	COG0643	Histidine kinase
G9455_16390	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
G9455_16415	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
G9455_16425	COG1684	flagellar biosynthetic protein fliR
G9455_16480	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
G9455_16490	COG1677	Flagellar hook-basal body complex protein FliE
G9455_16505	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
G9455_16525	COG2994	toxin metabolic process
G9455_16535	COG2274	protein secretion by the type I secretion system
G9455_16545	COG2274	protein secretion by the type I secretion system
G9455_16550	COG0745	RESPONSE REGULATOR receiver
G9455_16565	COG1737	Transcriptional regulator
G9455_16570	COG0469	pyruvate kinase activity
G9455_16580	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
G9455_16585	COG1960	acyl-CoA dehydrogenase activity
G9455_16595	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
G9455_16605	COG0243	molybdopterin cofactor binding
G9455_16610	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
G9455_16615	COG0583	DNA-binding transcription factor activity
G9455_16650	COG1454	alcohol dehydrogenase
G9455_16650	COG1012	belongs to the aldehyde dehydrogenase family
G9455_16660	COG1454	alcohol dehydrogenase
G9455_16660	COG1012	belongs to the aldehyde dehydrogenase family
G9455_16665	COG1882	Formate acetyltransferase
G9455_16670	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
G9455_16680	COG4869	propanediol catabolic process
G9455_16720	COG4409	exo-alpha-(2->6)-sialidase activity
G9455_16725	COG2731	YhcH YjgK YiaL family protein
G9455_16730	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
G9455_16740	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
G9455_16745	COG1737	Transcriptional regulator
G9455_16750	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
G9455_16755	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
G9455_16760	COG1349	DNA-binding transcription factor activity
G9455_16765	COG0738	Major facilitator superfamily
G9455_16775	COG1070	Carbohydrate kinase
G9455_16795	COG4172	Belongs to the ABC transporter superfamily
G9455_16800	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
G9455_16810	COG0747	negative chemotaxis
G9455_16825	COG1388	LysM domain
G9455_16825	COG1376	ErfK ybiS ycfS ynhG family protein
G9455_16840	COG3129	Specifically methylates the adenine in position 1618 of 23S rRNA
G9455_16845	COG0791	NLP P60 protein
G9455_16850	COG2091	lysine biosynthetic process via aminoadipic acid
G9455_16855	COG3118	belongs to the thioredoxin family
G9455_16865	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
G9455_16870	COG0788	formyltetrahydrofolate deformylase activity
G9455_16880	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
G9455_16900	COG0366	Alpha amylase catalytic
G9455_16905	COG0741	lytic transglycosylase activity
G9455_16905	COG0739	heme binding
G9455_16905	COG1196	nuclear chromosome segregation
G9455_16910	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
G9455_16915	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
G9455_16925	COG0673	inositol 2-dehydrogenase activity
G9455_16950	COG1032	radical SAM domain protein
G9455_16960	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
G9455_16965	COG1566	PFAM secretion protein HlyD family protein
G9455_16970	COG2203	Gaf domain
G9455_16970	COG2199	diguanylate cyclase activity
G9455_16975	COG1752	Esterase of the alpha-beta hydrolase superfamily
G9455_16980	COG0733	neurotransmitter:sodium symporter activity
G9455_17010	COG0281	malic enzyme
G9455_17020	COG0534	Mate efflux family protein
G9455_17035	COG2233	PERMEase
G9455_17040	COG0095	Lipoate-protein ligase
G9455_17045	COG1115	amino acid carrier protein
G9455_17050	COG0019	diaminopimelate decarboxylase activity
G9455_17060	COG0678	peroxiredoxin activity
G9455_17070	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
G9455_17090	COG1131	(ABC) transporter
G9455_17095	COG0545	Peptidyl-prolyl cis-trans isomerase
G9455_17100	COG3142	Participates in the control of copper homeostasis
G9455_17125	COG5002	protein histidine kinase activity
G9455_17130	COG0745	RESPONSE REGULATOR receiver
G9455_17135	COG0346	lactoylglutathione lyase activity
G9455_17140	COG1804	L-carnitine dehydratase bile acid-inducible protein F
G9455_17145	COG1960	acyl-CoA dehydrogenase activity
G9455_17150	COG3284	Transcriptional regulator
G9455_17155	COG1012	belongs to the aldehyde dehydrogenase family
G9455_17165	COG0697	spore germination
G9455_17170	COG4565	transcriptional regulatory protein
G9455_17175	COG3290	protein histidine kinase activity
G9455_17180	COG0281	malic enzyme
G9455_17195	COG1846	Transcriptional regulator
G9455_17200	COG1566	PFAM secretion protein HlyD family protein
G9455_17230	COG0602	queuosine metabolic process
G9455_17235	COG1328	CTP reductase activity
G9455_17245	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
G9455_17250	COG3115	cell septum assembly
G9455_17255	COG1196	nuclear chromosome segregation
G9455_17265	COG2860	membrane
G9455_17275	COG3108	Peptidase M15
G9455_17280	COG2989	Protein conserved in bacteria
G9455_17295	COG0463	Glycosyl transferase, family 2
G9455_17310	COG0366	Alpha amylase catalytic
G9455_17345	COG3706	GGDEF domain
G9455_17350	COG0037	tRNA processing
G9455_17355	COG3590	peptidase
G9455_17365	COG0488	(ABC) transporter
G9455_17375	COG0531	amino acid
G9455_17390	COG0814	amino acid
G9455_17405	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
G9455_17410	COG1982	Orn Lys Arg decarboxylase major
G9455_17415	COG0531	amino acid
G9455_17420	COG3710	Transcriptional regulator
G9455_17425	COG0825	malonyl-CoA metabolic process
G9455_17435	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
G9455_17440	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
G9455_17445	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
G9455_17450	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
G9455_17455	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
G9455_17470	COG0750	zinc metalloprotease
G9455_17475	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
G9455_17480	COG0575	Belongs to the CDS family
G9455_17485	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
G9455_17490	COG0233	cytoplasmic translational termination
G9455_17495	COG0528	UMP kinase activity
G9455_17500	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
G9455_17505	COG0052	Belongs to the universal ribosomal protein uS2 family
G9455_17510	COG0024	Methionine aminopeptidase
G9455_17515	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
G9455_17520	COG2171	N-acyltransferase activity
G9455_17530	COG1263	PTS System
G9455_17530	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
G9455_17540	COG4580	involved in the transport of maltose and maltodextrins
G9455_17550	COG0564	pseudouridine synthase activity
G9455_17555	COG3098	single-species biofilm formation
G9455_17580	COG5595	Zn-ribbon-containing, possibly nucleic-acid-binding protein (DUF2310)
G9455_17590	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
G9455_17590	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
G9455_17600	COG3706	GGDEF domain
G9455_17605	COG1611	Belongs to the LOG family
G9455_17610	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
G9455_17615	COG0473	3-isopropylmalate dehydrogenase activity
G9455_17625	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
G9455_17630	COG2363	Small membrane protein
G9455_17640	COG0583	DNA-binding transcription factor activity
G9455_17645	COG0840	transmembrane signaling receptor activity
G9455_17650	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
G9455_17665	COG1477	protein flavinylation
G9455_17670	COG2871	sodium ion transport
G9455_17675	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
G9455_17680	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
G9455_17685	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
G9455_17690	COG1805	sodium ion transport
G9455_17695	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
G9455_17700	COG0271	Belongs to the BolA IbaG family
G9455_17705	COG2813	Specifically methylates the guanine in position
G9455_17715	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
G9455_17725	COG2211	Major facilitator Superfamily
G9455_17730	COG3248	Nucleoside-binding outer membrane protein
G9455_17735	COG1666	GTP binding
G9455_17740	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
G9455_17745	COG0693	protein deglycase activity
G9455_17780	COG3501	Rhs element vgr protein
G9455_17795	COG2771	luxR family
G9455_17805	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
G9455_17805	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
G9455_17810	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
G9455_17820	COG1151	hydroxylamine reductase activity
G9455_17825	COG0783	Belongs to the Dps family
G9455_17850	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
G9455_17865	COG4221	oxidoreductase activity
G9455_17875	COG0415	Belongs to the DNA photolyase family
G9455_17880	COG0789	Transcriptional regulator
G9455_17885	COG3272	Protein of unknown function (DUF1722)
G9455_17915	COG0077	Prephenate dehydratase
G9455_17915	COG1605	Chorismate mutase
G9455_17945	COG5377	YqaJ viral recombinase family
G9455_17990	COG2003	Belongs to the UPF0758 family
G9455_18000	COG0602	queuosine metabolic process
G9455_18005	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
G9455_18030	COG0720	synthase
G9455_18065	COG0514	ATP-dependent DNA helicase (RecQ)
G9455_18070	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
G9455_18095	COG4771	TonB-dependent receptor
G9455_18115	COG1116	anion transmembrane transporter activity
G9455_18155	COG2226	methyltransferase
G9455_18205	COG2133	pyrroloquinoline quinone binding
G9455_18215	COG0840	transmembrane signaling receptor activity
G9455_18225	COG0300	oxidoreductase activity
G9455_18250	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
G9455_18265	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
G9455_18275	COG0826	peptidase U32
G9455_18280	COG1280	lysine exporter protein (LysE YggA)
G9455_18295	COG0840	transmembrane signaling receptor activity
G9455_18310	COG0643	Histidine kinase
G9455_18310	COG2198	Histidine kinase
G9455_18320	COG0835	chemotaxis
G9455_18325	COG0840	transmembrane signaling receptor activity
G9455_18335	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
G9455_18340	COG2201	protein-glutamate methylesterase activity
G9455_18345	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
G9455_18370	COG2200	EAL domain
G9455_18370	COG2199	diguanylate cyclase activity
G9455_18370	COG2203	Gaf domain
G9455_18380	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
G9455_18395	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
G9455_18400	COG0305	Participates in initiation and elongation during chromosome replication
G9455_18410	COG2200	EAL domain
G9455_18415	COG0737	Belongs to the 5'-nucleotidase family
G9455_18435	COG2204	response regulator
G9455_18440	COG0545	Peptidyl-prolyl cis-trans isomerase
G9455_18455	COG1047	Peptidyl-prolyl cis-trans
G9455_18460	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
G9455_18470	COG0835	chemotaxis
G9455_18470	COG0784	Response regulator, receiver
G9455_18475	COG0429	hydrolase of the alpha beta-hydrolase fold
G9455_18480	COG5001	Diguanylate cyclase
G9455_18480	COG4251	negative regulation of phosphorylation
G9455_18480	COG3706	GGDEF domain
G9455_18480	COG2203	Gaf domain
G9455_18485	COG3089	Belongs to the UPF0270 family
G9455_18495	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
G9455_18500	COG0463	Glycosyl transferase, family 2
G9455_18505	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
G9455_18505	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
G9455_18510	COG0726	polysaccharide deacetylase
G9455_18515	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
G9455_18520	COG2076	Multidrug Resistance protein
G9455_18525	COG2076	Multidrug Resistance protein
G9455_18530	COG3954	Phosphoribulokinase
G9455_18545	COG1765	OsmC-like protein
G9455_18555	COG2226	methyltransferase
G9455_18560	COG3397	chitin binding
G9455_18575	COG2202	Pas domain
G9455_18575	COG2205	protein histidine kinase activity
G9455_18585	COG3655	Transcriptional regulator
G9455_18590	COG2814	Major facilitator Superfamily
G9455_18595	COG4771	TonB-dependent receptor
G9455_18615	COG0748	coenzyme F420 binding
G9455_18620	COG3721	Heme iron utilization protein
G9455_18630	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
G9455_18655	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
G9455_18660	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
G9455_18665	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
G9455_18685	COG0741	lytic transglycosylase activity
G9455_18690	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
G9455_18785	COG0616	signal peptide processing
G9455_18800	COG1802	Transcriptional regulator
G9455_18800	COG4626	Terminase
G9455_18850	COG0464	growth
G9455_18860	COG4416	COG NOG18757 non supervised orthologous group
G9455_18990	COG0582	viral genome integration into host DNA
G9455_18995	COG0488	(ABC) transporter
G9455_19005	COG2252	PERMEase
G9455_19010	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
G9455_19015	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
G9455_19025	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
G9455_19035	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
G9455_19040	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
G9455_19045	COG2967	ApaG domain
G9455_19050	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
G9455_19060	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
G9455_19065	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
G9455_19080	COG0318	PFAM AMP-dependent synthetase and ligase
G9455_19090	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
G9455_19095	COG0211	Belongs to the bacterial ribosomal protein bL27 family
G9455_19100	COG0261	This protein binds to 23S rRNA in the presence of protein L20
G9455_19105	COG0142	geranyltranstransferase activity
G9455_19110	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
G9455_19115	COG0330	HflC and HflK could
G9455_19120	COG0330	HflC and HflK could
G9455_19125	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
G9455_19130	COG1923	regulation of RNA biosynthetic process
G9455_19135	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
G9455_19140	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
G9455_19150	COG0802	atpase or kinase
G9455_19155	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
G9455_19155	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
G9455_19175	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
G9455_19180	COG2011	ABC-type metal ion transport system permease component
G9455_19185	COG1464	Belongs to the NlpA lipoprotein family
G9455_19195	COG0840	transmembrane signaling receptor activity
G9455_19220	COG0784	Response regulator, receiver
G9455_19220	COG5002	protein histidine kinase activity
G9455_19220	COG2198	Histidine kinase
G9455_19240	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
G9455_19255	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
G9455_19260	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
G9455_19270	COG2716	regulation of RNA biosynthetic process
G9455_19275	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
G9455_19280	COG3013	Belongs to the UPF0304 family
G9455_19290	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
G9455_19295	COG0857	belongs to the CobB CobQ family
G9455_19295	COG0280	phosphate acetyltransferase
G9455_19305	COG0028	Belongs to the TPP enzyme family
G9455_19320	COG0671	phosphoesterase, PA-phosphatase related
G9455_19330	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
G9455_19335	COG0473	3-isopropylmalate dehydrogenase activity
G9455_19340	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
G9455_19345	COG0066	3-isopropylmalate dehydratase activity
G9455_19365	COG1178	ABC-type Fe3 transport system permease component
G9455_19370	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
G9455_19375	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
G9455_19385	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
G9455_19415	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
G9455_19420	COG0564	pseudouridine synthase activity
G9455_19435	COG3300	MHYT domain
G9455_19435	COG5001	Diguanylate cyclase
G9455_19445	COG0459	protein refolding
G9455_19450	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
G9455_19455	COG0534	Mate efflux family protein
G9455_19460	COG3030	protein affecting phage T7 exclusion by the F plasmid
G9455_19465	COG1027	Aspartate ammonia-lyase
G9455_19470	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
G9455_19480	COG0477	Major facilitator Superfamily
G9455_19500	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
G9455_19510	COG0673	inositol 2-dehydrogenase activity
G9455_19520	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
G9455_19525	COG0635	Involved in the biosynthesis of porphyrin-containing compound
G9455_19530	COG3036	rescue of stalled ribosome
G9455_19535	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
G9455_19545	COG0138	bifunctional purine biosynthesis protein purh
G9455_19550	COG0151	Belongs to the GarS family
G9455_19580	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
G9455_19585	COG0358	DNA primase activity
G9455_19590	COG1610	YqeY-like protein
G9455_19595	COG0828	Belongs to the bacterial ribosomal protein bS21 family
G9455_19600	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
G9455_19615	COG1238	metal cluster binding
G9455_19620	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
G9455_19625	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
G9455_19630	COG0585	pseudouridine synthase activity
G9455_19640	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
G9455_19645	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
G9455_19650	COG0148	phosphopyruvate hydratase activity
G9455_19655	COG0504	CTP synthase activity
G9455_19660	COG3956	TIGRFAM MazG family protein
G9455_19665	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
G9455_19670	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
G9455_19680	COG4807	Protein conserved in bacteria
G9455_19685	COG3023	N-Acetylmuramoyl-L-alanine amidase
G9455_19690	COG1349	DNA-binding transcription factor activity
G9455_19700	COG2222	sugar isomerase
G9455_19705	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
G9455_19715	COG3716	PTS system mannose fructose sorbose family IID component
G9455_19720	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
G9455_19725	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
G9455_19740	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
G9455_19745	COG1381	Involved in DNA repair and RecF pathway recombination
G9455_19755	COG0571	ribonuclease III activity
G9455_19760	COG0681	Belongs to the peptidase S26 family
G9455_19765	COG0481	GTPase activity
G9455_19780	COG3073	An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E
G9455_19785	COG1595	DNA-templated transcription, initiation
G9455_19790	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
G9455_19800	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
G9455_19805	COG0354	folic acid binding
G9455_19840	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
G9455_19845	COG0191	fructose-bisphosphate aldolase activity
G9455_19850	COG0126	phosphoglycerate kinase activity
G9455_19855	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
G9455_19860	COG1940	carbohydrate kinase activity
G9455_19865	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
G9455_19880	COG4991	sh3 domain protein
G9455_19885	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
G9455_19900	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
G9455_19920	COG1505	serine-type exopeptidase activity
G9455_19925	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
G9455_19930	COG0765	amino acid transport
G9455_19935	COG0765	amino acid transport
G9455_19940	COG1126	abc transporter atp-binding protein
G9455_19945	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
G9455_19950	COG1136	(ABC) transporter
G9455_19950	COG0577	efflux transmembrane transporter activity
G9455_19955	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
G9455_19960	COG0745	RESPONSE REGULATOR receiver
G9455_19965	COG2205	protein histidine kinase activity
G9455_20000	COG2070	2-Nitropropane dioxygenase
G9455_20025	COG1858	cytochrome C peroxidase
G9455_20030	COG1912	Pfam S-adenosyl-l-methionine hydroxide adenosyltransferase
G9455_20050	COG0513	Belongs to the DEAD box helicase family
G9455_20070	COG0154	amidase activity
G9455_20075	COG2957	Belongs to the agmatine deiminase family
G9455_20090	COG1902	pentaerythritol trinitrate reductase activity
G9455_20125	COG5001	Diguanylate cyclase
G9455_20135	COG0714	Associated with various cellular activities
G9455_20145	COG0456	acetyltransferase
G9455_20155	COG1022	Amp-dependent synthetase and ligase
G9455_20165	COG2918	glutathione biosynthetic process
G9455_20170	COG0612	Peptidase, M16
G9455_20175	COG1238	metal cluster binding
G9455_20200	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
G9455_20205	COG0359	binds to the 23S rRNA
G9455_20210	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
G9455_20215	COG0360	Binds together with S18 to 16S ribosomal RNA
G9455_20220	COG1914	H( )-stimulated, divalent metal cation uptake system
G9455_20240	COG2153	protein acetylation
G9455_20250	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
G9455_20255	COG0557	exoribonuclease II activity
G9455_20260	COG3706	GGDEF domain
G9455_20265	COG1854	S-ribosylhomocysteine lyase activity
G9455_20280	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
G9455_20280	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
G9455_20340	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
G9455_20345	COG1047	Peptidyl-prolyl cis-trans
G9455_20350	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
G9455_20355	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
G9455_20360	COG0196	riboflavin kinase activity
G9455_20370	COG0728	peptidoglycan biosynthetic process
G9455_20375	COG0268	Binds directly to 16S ribosomal RNA
G9455_20380	COG0640	Transcriptional regulator
G9455_20385	COG0583	DNA-binding transcription factor activity
G9455_20395	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
G9455_20400	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
G9455_20405	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
G9455_20415	COG1051	belongs to the nudix hydrolase family
G9455_20420	COG3066	DNA modification
G9455_20430	COG0335	large ribosomal subunit rRNA binding
G9455_20435	COG0336	Belongs to the RNA methyltransferase TrmD family
G9455_20440	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
G9455_20445	COG0228	four-way junction DNA binding
G9455_20450	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
G9455_20455	COG4137	Cytochrome C assembly protein
G9455_20460	COG4536	flavin adenine dinucleotide binding
G9455_20470	COG1017	nitric oxide dioxygenase activity
G9455_20470	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
G9455_20475	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
G9455_20480	COG0039	L-malate dehydrogenase activity
G9455_20485	COG4160	amino acid transport
G9455_20490	COG4215	(ABC) transporter
G9455_20495	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
G9455_20500	COG1126	abc transporter atp-binding protein
G9455_20505	COG1438	arginine binding
G9455_20510	COG2837	iron assimilation
G9455_20515	COG3842	ATPase activity
G9455_20525	COG1840	ABC-type Fe3 transport system, periplasmic component
G9455_20530	COG0347	Belongs to the P(II) protein family
G9455_20545	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
G9455_20550	COG0583	DNA-binding transcription factor activity
G9455_20565	COG1929	Belongs to the glycerate kinase type-1 family
G9455_20570	COG2610	gluconate transmembrane transporter activity
G9455_20575	COG3835	regulator
G9455_20585	COG3112	Uncharacterised protein family (UPF0231)
G9455_20600	COG0840	transmembrane signaling receptor activity
G9455_20620	COG0513	Belongs to the DEAD box helicase family
G9455_20660	COG1448	Aminotransferase
G9455_20675	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
G9455_20680	COG1328	CTP reductase activity
G9455_20700	COG4946	Tricorn protease homolog
G9455_20700	COG0793	Belongs to the peptidase S41A family
G9455_20730	COG0840	transmembrane signaling receptor activity
G9455_20735	COG3397	chitin binding
G9455_20740	COG0583	DNA-binding transcription factor activity
G9455_20745	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
G9455_20750	COG4208	sulfate ABC transporter
G9455_20755	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
G9455_20765	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
G9455_20770	COG3174	membrane
G9455_20775	COG0110	maltose O-acetyltransferase activity
G9455_20800	COG0165	Argininosuccinate lyase
G9455_20805	COG0137	argininosuccinate synthase activity
G9455_20815	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
G9455_20820	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
G9455_20830	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
G9455_20840	COG0460	homoserine dehydrogenase
G9455_20840	COG0527	aspartate kinase activity
G9455_20845	COG0626	cystathionine gamma-synthase activity
G9455_20855	COG3708	Transcriptional regulator
G9455_20855	COG2207	Transcriptional regulator
G9455_20860	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
G9455_20865	COG0814	amino acid
G9455_20870	COG1218	3'(2'),5'-bisphosphate nucleotidase
G9455_20875	COG0494	nUDIX hydrolase
G9455_20880	COG1011	Hydrolase
G9455_20885	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
G9455_20900	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
G9455_20910	COG3156	type II secretion system protein K
G9455_20915	COG4795	General secretion pathway protein
G9455_20920	COG2165	general secretion pathway protein
G9455_20935	COG2165	general secretion pathway protein
G9455_20940	COG1459	type II secretion system
G9455_20945	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
G9455_20955	COG3031	protein transport across the cell outer membrane
G9455_20965	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
G9455_20990	COG0456	acetyltransferase
G9455_20995	COG3133	Outer membrane lipoprotein
G9455_21010	COG2771	luxR family
G9455_21015	COG3916	Acyl-homoserine-lactone synthase
G9455_21025	COG4776	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction
G9455_21030	COG1309	transcriptional regulator
G9455_21040	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
G9455_21040	COG2213	PTS system mannitol-specific
G9455_21045	COG0246	Mannitol dehydrogenase
G9455_21050	COG3722	fumarate hydratase activity
G9455_21055	COG3263	regulation of cellular component size
G9455_21080	COG1671	Belongs to the UPF0178 family
G9455_21095	COG1988	membrane-bound metal-dependent
G9455_21100	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
G9455_21105	COG0513	Belongs to the DEAD box helicase family
G9455_21130	COG1575	Belongs to the MenA family. Type 1 subfamily
G9455_21135	COG1169	isochorismate synthase
G9455_21140	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
G9455_21145	COG0596	Alpha beta hydrolase
G9455_21150	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
G9455_21155	COG1441	menaquinone biosynthetic process
G9455_21160	COG0318	PFAM AMP-dependent synthetase and ligase
G9455_21175	COG3539	Fimbrial protein
G9455_21180	COG3121	Chaperone
G9455_21185	COG3188	usher protein
G9455_21195	COG3539	Fimbrial protein
G9455_21205	COG3291	Pkd domain containing protein
G9455_21210	COG2949	membrane
G9455_21215	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
G9455_21225	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
G9455_21230	COG5380	lipid catabolic process
G9455_21245	COG4533	DNA binding
G9455_21255	COG2873	o-acetylhomoserine
G9455_21265	COG1979	alcohol dehydrogenase
G9455_21285	COG4221	oxidoreductase activity
G9455_21305	COG1285	pathogenesis
G9455_21325	COG1368	sulfuric ester hydrolase activity
G9455_21330	COG1522	sequence-specific DNA binding
G9455_21340	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
G9455_21345	COG1418	mRNA catabolic process
G9455_21350	COG1058	Belongs to the CinA family
G9455_21350	COG1546	Belongs to the CinA family
G9455_21360	COG0842	Transport permease protein
G9455_21360	COG1129	ABC transporter
G9455_21375	COG0561	phosphatase activity
G9455_21380	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
G9455_21400	COG1011	Hydrolase
G9455_21415	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
G9455_21420	COG0019	diaminopimelate decarboxylase activity
G9455_21430	COG1965	Belongs to the frataxin family
G9455_21435	COG0400	carboxylic ester hydrolase activity
G9455_21440	COG3072	Adenylate cyclase
G9455_21445	COG0181	hydroxymethylbilane synthase activity
G9455_21455	COG2959	enzyme of heme biosynthesis
G9455_21470	COG1494	fructose-1,6-bisphosphatase
G9455_21510	COG1733	regulation of RNA biosynthetic process
G9455_21530	COG3932	Exopolysaccharide synthesis, ExoD
G9455_21535	COG0814	amino acid
G9455_21540	COG3706	GGDEF domain
G9455_21555	COG3417	Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1B (PBP1b)
G9455_21565	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
G9455_21570	COG2022	thiamine diphosphate biosynthetic process
G9455_21580	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
G9455_21585	COG0352	thiamine-phosphate diphosphorylase activity
G9455_21590	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
G9455_21610	COG0745	RESPONSE REGULATOR receiver
G9455_21615	COG0642	Histidine kinase
G9455_21625	COG0189	ligase activity
G9455_21675	COG3171	Protein conserved in bacteria
G9455_21690	COG3188	usher protein
G9455_21730	COG1639	'signal transduction protein
G9455_21740	COG2321	neutral zinc metallopeptidase
G9455_21745	COG3700	Belongs to the class B bacterial acid phosphatase family
G9455_21765	COG1366	Belongs to the anti-sigma-factor antagonist family
G9455_21770	COG2172	sigma factor antagonist activity
G9455_21775	COG2205	protein histidine kinase activity
G9455_21775	COG5002	protein histidine kinase activity
G9455_21775	COG0784	Response regulator, receiver
G9455_21780	COG3437	response regulator, receiver
G9455_21790	COG0477	Major facilitator Superfamily
G9455_21805	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
G9455_21810	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
G9455_21810	COG1263	PTS System
G9455_21830	COG0312	modulator of DNA gyrase
G9455_21835	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
G9455_21845	COG3164	Protein of unknown function
G9455_21850	COG1530	ribonuclease E activity
G9455_21855	COG0424	maF-like protein
G9455_21860	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
G9455_21865	COG1792	Involved in formation and maintenance of cell shape
G9455_21870	COG1077	Cell shape determining protein MreB Mrl
G9455_21895	COG4968	Prepilin-type N-terminal cleavage methylation domain
G9455_21900	COG4969	Belongs to the N-Me-Phe pilin family
G9455_21915	COG1459	type II secretion system
G9455_21920	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
G9455_21930	COG2842	Transposition protein
G9455_21965	COG2199	diguanylate cyclase activity
G9455_21965	COG2200	EAL domain
G9455_21970	COG2200	EAL domain
G9455_21975	COG0387	Pfam Sodium calcium exchanger
G9455_21980	COG2986	histidine ammonia-lyase
G9455_21985	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
G9455_21990	COG0010	Belongs to the arginase family
G9455_21995	COG1228	amidohydrolase
G9455_22000	COG2188	Transcriptional regulator
G9455_22005	COG0288	reversible hydration of carbon dioxide
G9455_22015	COG2177	Part of the ABC transporter FtsEX involved in
G9455_22020	COG2884	Cell division ATP-binding protein ftsE
G9455_22025	COG0552	protein localization to endoplasmic reticulum
G9455_22030	COG0742	ribosomal rna small subunit methyltransferase
G9455_22055	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
G9455_22065	COG0741	lytic transglycosylase activity
G9455_22075	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
G9455_22085	COG2095	MarC family integral membrane protein
G9455_22095	COG1301	dicarboxylic acid transport
G9455_22120	COG3714	YhhN family
G9455_22140	COG1770	oligopeptidase
G9455_22155	COG4221	oxidoreductase activity
G9455_22160	COG0583	DNA-binding transcription factor activity
G9455_22165	COG2249	NAD(P)H dehydrogenase (quinone) activity
G9455_22215	COG0203	ribosomal protein L17
G9455_22220	COG0202	RNA polymerase activity
G9455_22225	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
G9455_22230	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
G9455_22235	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
G9455_22240	COG0257	Belongs to the bacterial ribosomal protein bL36 family
G9455_22245	COG0201	protein transport
G9455_22250	COG0200	Binds to the 23S rRNA
G9455_22255	COG1841	ribosomal large subunit assembly
G9455_22260	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
G9455_22265	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
G9455_22270	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
G9455_22275	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
G9455_22280	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
G9455_22285	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
G9455_22290	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
G9455_22295	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
G9455_22300	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
G9455_22305	COG0255	Belongs to the universal ribosomal protein uL29 family
G9455_22310	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
G9455_22315	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
G9455_22320	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
G9455_22325	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
G9455_22330	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
G9455_22335	COG0089	rRNA binding
G9455_22340	COG0088	Forms part of the polypeptide exit tunnel
G9455_22345	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
G9455_22350	COG0051	transcription antitermination factor activity, RNA binding
G9455_22365	COG0745	RESPONSE REGULATOR receiver
G9455_22370	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
G9455_22375	COG2183	response to ionizing radiation
G9455_22395	COG0596	Alpha beta hydrolase
G9455_22400	COG1040	competence protein
G9455_22405	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
G9455_22405	COG0316	Belongs to the HesB IscA family
G9455_22410	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
G9455_22415	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
G9455_22420	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
G9455_22425	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
G9455_22430	COG4942	peptidase
G9455_22440	COG1609	Transcriptional regulator
G9455_22445	COG0800	Aldolase
G9455_22450	COG0129	dihydroxy-acid dehydratase activity
G9455_22455	COG3265	gluconokinase activity
G9455_22460	COG2610	gluconate transmembrane transporter activity
G9455_22465	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
G9455_22470	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
G9455_22480	COG0456	acetyltransferase
G9455_22490	COG1490	D-aminoacyl-tRNA deacylase activity
G9455_22495	COG1295	ribonuclease BN
G9455_22505	COG0174	glutamine synthetase
G9455_22515	COG3852	Histidine kinase
G9455_22520	COG2204	response regulator
G9455_22525	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
G9455_22530	COG0635	Involved in the biosynthesis of porphyrin-containing compound
G9455_22540	COG3078	GTPase activator activity
G9455_22550	COG0218	Necessary for normal cell division and for the maintenance of normal septation
G9455_22560	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
G9455_22565	COG0408	coproporphyrinogen oxidase activity
G9455_22570	COG0009	L-threonylcarbamoyladenylate synthase
G9455_22580	COG0551	DNA topoisomerase type I activity
G9455_22585	COG2922	Belongs to the Smg family
G9455_22590	COG0758	DNA mediated transformation
G9455_22600	COG0242	peptide deformylase activity
G9455_22605	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
G9455_22610	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
G9455_22610	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
G9455_22615	COG0569	domain protein
G9455_22620	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
G9455_22625	COG1322	Protein conserved in bacteria
G9455_22645	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
G9455_22650	COG0686	Belongs to the AlaDH PNT family
G9455_22655	COG0519	Catalyzes the synthesis of GMP from XMP
G9455_22655	COG0518	GMP synthase (glutamine-hydrolyzing) activity
G9455_22670	COG1396	sequence-specific DNA binding
G9455_22675	COG1012	belongs to the aldehyde dehydrogenase family
G9455_22685	COG2962	Rard protein
G9455_22695	COG1280	lysine exporter protein (LysE YggA)
G9455_22705	COG2391	methyltransferase activity
G9455_22710	COG1280	lysine exporter protein (LysE YggA)
G9455_22755	COG0583	DNA-binding transcription factor activity
G9455_22760	COG1943	Transposase
G9455_22775	COG0210	DNA helicase
G9455_22800	COG0583	DNA-binding transcription factor activity
G9455_22820	COG1262	PFAM Formylglycine-generating sulfatase enzyme
G9455_22825	COG0385	Bile acid
G9455_22830	COG0531	amino acid
G9455_22835	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
G9455_22840	COG0531	amino acid
G9455_22845	COG2731	YhcH YjgK YiaL family protein
G9455_22850	COG3250	beta-galactosidase activity
G9455_22855	COG1609	Transcriptional regulator
G9455_22890	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
G9455_22895	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
G9455_22895	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
G9455_22900	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
G9455_22905	COG3074	FtsZ-dependent cytokinesis
G9455_22915	COG1045	serine acetyltransferase
G9455_22925	COG0745	RESPONSE REGULATOR receiver
G9455_22930	COG2205	protein histidine kinase activity
G9455_22935	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
G9455_22940	COG0534	Mate efflux family protein
G9455_22955	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
G9455_22960	COG2937	Belongs to the GPAT DAPAT family
G9455_22965	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
G9455_22970	COG3161	chorismate lyase activity
G9455_22975	COG1580	Controls the rotational direction of flagella during chemotaxis
G9455_22990	COG0604	alcohol dehydrogenase
G9455_22995	COG1609	Transcriptional regulator
G9455_23015	COG1519	Transferase
G9455_23020	COG0859	PFAM glycosyl transferase family 9
G9455_23025	COG0463	Glycosyl transferase, family 2
G9455_23030	COG0859	PFAM glycosyl transferase family 9
G9455_23035	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
G9455_23040	COG2990	Protein conserved in bacteria
G9455_23045	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
G9455_23055	COG0267	Belongs to the bacterial ribosomal protein bL33 family
G9455_23060	COG0227	Belongs to the bacterial ribosomal protein bL28 family
G9455_23065	COG2003	Belongs to the UPF0758 family
G9455_23070	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
G9455_23075	COG0756	dUTP diphosphatase activity
G9455_23080	COG1309	transcriptional regulator
G9455_23085	COG0668	transmembrane transport
G9455_23095	COG0166	Belongs to the GPI family
G9455_23100	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
G9455_23105	COG0583	DNA-binding transcription factor activity
G9455_23145	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
G9455_23150	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
G9455_23155	COG1739	Uncharacterized protein family UPF0029
G9455_23160	COG0006	proline dipeptidase activity
G9455_23165	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
G9455_23170	COG1250	3-hydroxyacyl-CoA dehydrogenase
G9455_23170	COG1024	Enoyl-CoA hydratase
G9455_23175	COG0183	Belongs to the thiolase family
G9455_23180	COG0745	RESPONSE REGULATOR receiver
G9455_23185	COG2205	protein histidine kinase activity
G9455_23200	COG0425	Belongs to the sulfur carrier protein TusA family
G9455_23205	COG0251	oxidation-reduction process
G9455_23215	COG2885	chlorophyll binding
G9455_23220	COG1335	isochorismatase
G9455_23225	COG2818	Glycosylase
G9455_23230	COG0752	glycyl-tRNA synthetase alpha subunit
G9455_23235	COG0751	glycine-tRNA ligase activity
G9455_23250	COG0529	Catalyzes the synthesis of activated sulfate
G9455_23250	COG2046	Belongs to the sulfate adenylyltransferase family
G9455_23270	COG0814	amino acid
G9455_23275	COG0348	domain, Protein
G9455_23285	COG0446	pyridine nucleotide-disulphide oxidoreductase
G9455_23290	COG0426	domain, Protein
G9455_23290	COG1773	rubredoxin
G9455_23295	COG3604	Transcriptional regulator
G9455_23300	COG2188	Transcriptional regulator
G9455_23315	COG1609	Transcriptional regulator
G9455_23355	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
G9455_23380	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
G9455_23395	COG3118	belongs to the thioredoxin family
G9455_23400	COG0513	Belongs to the DEAD box helicase family
G9455_23405	COG0248	Ppx GppA phosphatase
G9455_23420	COG0742	ribosomal rna small subunit methyltransferase
G9455_23440	COG0084	hydrolase, TatD family'
G9455_23445	COG0805	protein transport
G9455_23450	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
G9455_23460	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
G9455_23465	COG3165	ubiquinone biosynthetic process from chorismate
G9455_23475	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
G9455_23480	COG0402	S-adenosylhomocysteine deaminase activity