locus-tag	class	description
AHML_00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
AHML_00010	COG0592	DNA-directed DNA polymerase activity
AHML_00020	COG0187	DNA topoisomerase II activity
AHML_00030	COG2378	regulation of single-species biofilm formation
AHML_00035	COG0071	Belongs to the small heat shock protein (HSP20) family
AHML_00040	COG0071	Belongs to the small heat shock protein (HSP20) family
AHML_00045	COG3977	Valine--pyruvate aminotransferase
AHML_00060	COG2814	Major facilitator Superfamily
AHML_00065	COG0745	RESPONSE REGULATOR receiver
AHML_00070	COG2205	protein histidine kinase activity
AHML_00095	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AHML_00100	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AHML_00100	COG4191	Histidine kinase
AHML_00105	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AHML_00110	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AHML_00115	COG1309	transcriptional regulator
AHML_00125	COG0469	pyruvate kinase activity
AHML_00130	COG2271	Major facilitator Superfamily
AHML_00135	COG1840	ABC-type Fe3 transport system, periplasmic component
AHML_00155	COG0561	phosphatase activity
AHML_00160	COG2267	carboxylic ester hydrolase activity
AHML_00170	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AHML_00175	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
AHML_00180	COG1758	RNA polymerase activity
AHML_00190	COG0859	PFAM glycosyl transferase family 9
AHML_00195	COG3642	lipopolysaccharide core region biosynthetic process
AHML_00235	COG0589	response to stress
AHML_00240	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
AHML_00245	COG2199	diguanylate cyclase activity
AHML_00250	COG1528	Iron-storage protein
AHML_00255	COG2081	HI0933 family
AHML_00280	COG3550	peptidyl-serine autophosphorylation
AHML_00290	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
AHML_00295	COG1196	nuclear chromosome segregation
AHML_00325	COG2223	nitrite transmembrane transporter activity
AHML_00345	COG3188	usher protein
AHML_00365	COG2205	protein histidine kinase activity
AHML_00365	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AHML_00375	COG3275	phosphorelay sensor kinase activity
AHML_00380	COG3279	Response regulator of the LytR AlgR family
AHML_00385	COG2223	nitrite transmembrane transporter activity
AHML_00390	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
AHML_00395	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
AHML_00410	COG0583	DNA-binding transcription factor activity
AHML_00415	COG4206	TonB-dependent receptor
AHML_00420	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
AHML_00435	COG0402	S-adenosylhomocysteine deaminase activity
AHML_00440	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
AHML_00450	COG3165	ubiquinone biosynthetic process from chorismate
AHML_00455	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
AHML_00465	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
AHML_00470	COG0805	protein transport
AHML_00475	COG0084	hydrolase, TatD family'
AHML_00495	COG0742	ribosomal rna small subunit methyltransferase
AHML_00510	COG0248	Ppx GppA phosphatase
AHML_00515	COG0513	Belongs to the DEAD box helicase family
AHML_00520	COG3118	belongs to the thioredoxin family
AHML_00525	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
AHML_00535	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
AHML_00560	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AHML_00590	COG0559	Belongs to the binding-protein-dependent transport system permease family
AHML_00600	COG1609	Transcriptional regulator
AHML_00615	COG2188	Transcriptional regulator
AHML_00620	COG3604	Transcriptional regulator
AHML_00625	COG0426	domain, Protein
AHML_00625	COG1773	rubredoxin
AHML_00630	COG0446	pyridine nucleotide-disulphide oxidoreductase
AHML_00640	COG0348	domain, Protein
AHML_00645	COG0814	amino acid
AHML_00665	COG0529	Catalyzes the synthesis of activated sulfate
AHML_00665	COG2046	Belongs to the sulfate adenylyltransferase family
AHML_00680	COG0751	glycine-tRNA ligase activity
AHML_00685	COG0752	glycyl-tRNA synthetase alpha subunit
AHML_00690	COG2818	Glycosylase
AHML_00695	COG1335	isochorismatase
AHML_00700	COG2885	chlorophyll binding
AHML_00705	COG0251	oxidation-reduction process
AHML_00710	COG0425	Belongs to the sulfur carrier protein TusA family
AHML_00725	COG2205	protein histidine kinase activity
AHML_00730	COG0745	RESPONSE REGULATOR receiver
AHML_00735	COG0183	Belongs to the thiolase family
AHML_00740	COG1250	3-hydroxyacyl-CoA dehydrogenase
AHML_00740	COG1024	Enoyl-CoA hydratase
AHML_00745	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AHML_00750	COG0006	proline dipeptidase activity
AHML_00755	COG1739	Uncharacterized protein family UPF0029
AHML_00760	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
AHML_00765	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
AHML_00785	COG0583	DNA-binding transcription factor activity
AHML_00790	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
AHML_00795	COG0166	Belongs to the GPI family
AHML_00810	COG0668	transmembrane transport
AHML_00815	COG1309	transcriptional regulator
AHML_00820	COG0756	dUTP diphosphatase activity
AHML_00825	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
AHML_00830	COG2003	Belongs to the UPF0758 family
AHML_00835	COG0227	Belongs to the bacterial ribosomal protein bL28 family
AHML_00840	COG0267	Belongs to the bacterial ribosomal protein bL33 family
AHML_00850	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
AHML_00855	COG2990	Protein conserved in bacteria
AHML_00860	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
AHML_00865	COG0859	PFAM glycosyl transferase family 9
AHML_00870	COG0463	Glycosyl transferase, family 2
AHML_00875	COG0859	PFAM glycosyl transferase family 9
AHML_00880	COG1519	Transferase
AHML_00900	COG1609	Transcriptional regulator
AHML_00905	COG0604	alcohol dehydrogenase
AHML_00925	COG1580	Controls the rotational direction of flagella during chemotaxis
AHML_00930	COG3161	chorismate lyase activity
AHML_00935	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
AHML_00940	COG2937	Belongs to the GPAT DAPAT family
AHML_00945	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
AHML_00965	COG0534	Mate efflux family protein
AHML_00970	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
AHML_00975	COG2205	protein histidine kinase activity
AHML_00980	COG0745	RESPONSE REGULATOR receiver
AHML_00990	COG1045	serine acetyltransferase
AHML_01000	COG3074	FtsZ-dependent cytokinesis
AHML_01005	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
AHML_01010	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AHML_01010	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AHML_01015	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
AHML_01020	COG1609	Transcriptional regulator
AHML_01025	COG3250	beta-galactosidase activity
AHML_01030	COG2731	YhcH YjgK YiaL family protein
AHML_01035	COG0531	amino acid
AHML_01040	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AHML_01045	COG0531	amino acid
AHML_01050	COG0385	Bile acid
AHML_01055	COG1262	PFAM Formylglycine-generating sulfatase enzyme
AHML_01075	COG0583	DNA-binding transcription factor activity
AHML_01100	COG0210	DNA helicase
AHML_01105	COG1943	Transposase
AHML_01110	COG0583	DNA-binding transcription factor activity
AHML_01155	COG1280	lysine exporter protein (LysE YggA)
AHML_01160	COG2391	methyltransferase activity
AHML_01170	COG1280	lysine exporter protein (LysE YggA)
AHML_01180	COG2962	Rard protein
AHML_01190	COG1012	belongs to the aldehyde dehydrogenase family
AHML_01195	COG1396	sequence-specific DNA binding
AHML_01210	COG0518	GMP synthase (glutamine-hydrolyzing) activity
AHML_01210	COG0519	Catalyzes the synthesis of GMP from XMP
AHML_01215	COG0686	Belongs to the AlaDH PNT family
AHML_01220	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AHML_01240	COG1322	Protein conserved in bacteria
AHML_01245	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
AHML_01250	COG0569	domain protein
AHML_01255	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
AHML_01255	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
AHML_01260	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
AHML_01265	COG0242	peptide deformylase activity
AHML_01275	COG0758	DNA mediated transformation
AHML_01280	COG2922	Belongs to the Smg family
AHML_01285	COG0551	DNA topoisomerase type I activity
AHML_01295	COG0009	L-threonylcarbamoyladenylate synthase
AHML_01300	COG0408	coproporphyrinogen oxidase activity
AHML_01305	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
AHML_01315	COG0218	Necessary for normal cell division and for the maintenance of normal septation
AHML_01330	COG3078	GTPase activator activity
AHML_01340	COG0635	Involved in the biosynthesis of porphyrin-containing compound
AHML_01345	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
AHML_01350	COG2204	response regulator
AHML_01355	COG3852	Histidine kinase
AHML_01365	COG0174	glutamine synthetase
AHML_01375	COG1295	ribonuclease BN
AHML_01380	COG1490	D-aminoacyl-tRNA deacylase activity
AHML_01390	COG0456	acetyltransferase
AHML_01400	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
AHML_01405	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AHML_01410	COG2610	gluconate transmembrane transporter activity
AHML_01415	COG3265	gluconokinase activity
AHML_01420	COG0129	dihydroxy-acid dehydratase activity
AHML_01425	COG0800	Aldolase
AHML_01430	COG1609	Transcriptional regulator
AHML_01440	COG4942	peptidase
AHML_01445	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
AHML_01450	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AHML_01455	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
AHML_01460	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
AHML_01465	COG0316	Belongs to the HesB IscA family
AHML_01465	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
AHML_01470	COG1040	competence protein
AHML_01475	COG0596	Alpha beta hydrolase
AHML_01495	COG2183	response to ionizing radiation
AHML_01500	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
AHML_01505	COG0745	RESPONSE REGULATOR receiver
AHML_01520	COG0051	transcription antitermination factor activity, RNA binding
AHML_01525	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
AHML_01530	COG0088	Forms part of the polypeptide exit tunnel
AHML_01535	COG0089	rRNA binding
AHML_01540	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
AHML_01545	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
AHML_01550	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
AHML_01555	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
AHML_01560	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
AHML_01565	COG0255	Belongs to the universal ribosomal protein uL29 family
AHML_01570	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
AHML_01575	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
AHML_01580	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
AHML_01585	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
AHML_01590	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
AHML_01595	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
AHML_01600	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
AHML_01605	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
AHML_01610	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
AHML_01615	COG1841	ribosomal large subunit assembly
AHML_01620	COG0200	Binds to the 23S rRNA
AHML_01625	COG0201	protein transport
AHML_01630	COG0257	Belongs to the bacterial ribosomal protein bL36 family
AHML_01635	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
AHML_01640	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
AHML_01645	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
AHML_01650	COG0202	RNA polymerase activity
AHML_01655	COG0203	ribosomal protein L17
AHML_01680	COG2249	NAD(P)H dehydrogenase (quinone) activity
AHML_01685	COG0583	DNA-binding transcription factor activity
AHML_01690	COG4221	oxidoreductase activity
AHML_01705	COG1770	oligopeptidase
AHML_01730	COG3714	YhhN family
AHML_01755	COG1301	dicarboxylic acid transport
AHML_01765	COG2095	MarC family integral membrane protein
AHML_01785	COG0741	lytic transglycosylase activity
AHML_01790	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AHML_01815	COG0742	ribosomal rna small subunit methyltransferase
AHML_01830	COG0552	protein localization to endoplasmic reticulum
AHML_01835	COG2884	Cell division ATP-binding protein ftsE
AHML_01840	COG2177	Part of the ABC transporter FtsEX involved in
AHML_01850	COG0288	reversible hydration of carbon dioxide
AHML_01855	COG2188	Transcriptional regulator
AHML_01860	COG1228	amidohydrolase
AHML_01865	COG0010	Belongs to the arginase family
AHML_01870	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
AHML_01875	COG2986	histidine ammonia-lyase
AHML_01880	COG0387	Pfam Sodium calcium exchanger
AHML_01885	COG2200	EAL domain
AHML_01890	COG2199	diguanylate cyclase activity
AHML_01890	COG2200	EAL domain
AHML_01925	COG2842	Transposition protein
AHML_01935	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
AHML_01940	COG1459	type II secretion system
AHML_01960	COG4968	Prepilin-type N-terminal cleavage methylation domain
AHML_01985	COG1077	Cell shape determining protein MreB Mrl
AHML_01990	COG1792	Involved in formation and maintenance of cell shape
AHML_01995	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
AHML_02000	COG0424	maF-like protein
AHML_02005	COG1530	ribonuclease E activity
AHML_02010	COG3164	Protein of unknown function
AHML_02020	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AHML_02025	COG0312	modulator of DNA gyrase
AHML_02045	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AHML_02045	COG1263	PTS System
AHML_02050	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
AHML_02065	COG0477	Major facilitator Superfamily
AHML_02075	COG3437	response regulator, receiver
AHML_02080	COG0784	Response regulator, receiver
AHML_02080	COG2205	protein histidine kinase activity
AHML_02080	COG5002	protein histidine kinase activity
AHML_02085	COG2172	sigma factor antagonist activity
AHML_02090	COG1366	Belongs to the anti-sigma-factor antagonist family
AHML_02110	COG3700	Belongs to the class B bacterial acid phosphatase family
AHML_02115	COG2321	neutral zinc metallopeptidase
AHML_02125	COG1639	'signal transduction protein
AHML_02175	COG3188	usher protein
AHML_02190	COG3171	Protein conserved in bacteria
AHML_02235	COG0189	ligase activity
AHML_02240	COG1114	Component of the transport system for branched-chain amino acids
AHML_02250	COG0745	RESPONSE REGULATOR receiver
AHML_02270	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
AHML_02275	COG0352	thiamine-phosphate diphosphorylase activity
AHML_02280	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
AHML_02290	COG2022	thiamine diphosphate biosynthetic process
AHML_02295	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
AHML_02305	COG3417	Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1B (PBP1b)
AHML_02320	COG3706	GGDEF domain
AHML_02325	COG0814	amino acid
AHML_02330	COG3932	Exopolysaccharide synthesis, ExoD
AHML_02350	COG1733	regulation of RNA biosynthetic process
AHML_02390	COG1494	fructose-1,6-bisphosphatase
AHML_02405	COG2959	enzyme of heme biosynthesis
AHML_02415	COG0181	hydroxymethylbilane synthase activity
AHML_02420	COG3072	Adenylate cyclase
AHML_02425	COG0400	carboxylic ester hydrolase activity
AHML_02430	COG1965	Belongs to the frataxin family
AHML_02435	COG0019	diaminopimelate decarboxylase activity
AHML_02440	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
AHML_02455	COG1011	Hydrolase
AHML_02475	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
AHML_02480	COG0561	phosphatase activity
AHML_02495	COG0842	Transport permease protein
AHML_02495	COG1129	ABC transporter
AHML_02510	COG1546	Belongs to the CinA family
AHML_02510	COG1058	Belongs to the CinA family
AHML_02515	COG1418	mRNA catabolic process
AHML_02520	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
AHML_02530	COG1522	sequence-specific DNA binding
AHML_02535	COG1368	sulfuric ester hydrolase activity
AHML_02555	COG1285	pathogenesis
AHML_02575	COG4221	oxidoreductase activity
AHML_02595	COG1979	alcohol dehydrogenase
AHML_02605	COG2873	o-acetylhomoserine
AHML_02615	COG4533	DNA binding
AHML_02630	COG5380	lipid catabolic process
AHML_02635	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
AHML_02650	COG2949	membrane
AHML_02655	COG3291	Pkd domain containing protein
AHML_02675	COG3188	usher protein
AHML_02680	COG3121	Chaperone
AHML_02685	COG3539	Fimbrial protein
AHML_02700	COG0318	PFAM AMP-dependent synthetase and ligase
AHML_02705	COG1441	menaquinone biosynthetic process
AHML_02710	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
AHML_02715	COG0596	Alpha beta hydrolase
AHML_02720	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
AHML_02725	COG1169	isochorismate synthase
AHML_02730	COG1575	Belongs to the MenA family. Type 1 subfamily
AHML_02755	COG0513	Belongs to the DEAD box helicase family
AHML_02760	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
AHML_02765	COG1988	membrane-bound metal-dependent
AHML_02780	COG1671	Belongs to the UPF0178 family
AHML_02805	COG3263	regulation of cellular component size
AHML_02810	COG3722	fumarate hydratase activity
AHML_02815	COG0246	Mannitol dehydrogenase
AHML_02820	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
AHML_02820	COG2213	PTS system mannitol-specific
AHML_02830	COG1309	transcriptional regulator
AHML_02835	COG4776	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction
AHML_02845	COG3916	Acyl-homoserine-lactone synthase
AHML_02850	COG2771	luxR family
AHML_02865	COG3133	Outer membrane lipoprotein
AHML_02870	COG0456	acetyltransferase
AHML_02895	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
AHML_02905	COG3031	protein transport across the cell outer membrane
AHML_02915	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
AHML_02920	COG1459	type II secretion system
AHML_02925	COG2165	general secretion pathway protein
AHML_02940	COG2165	general secretion pathway protein
AHML_02945	COG4795	General secretion pathway protein
AHML_02950	COG3156	type II secretion system protein K
AHML_02960	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
AHML_02975	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
AHML_02980	COG1011	Hydrolase
AHML_02985	COG0494	nUDIX hydrolase
AHML_02990	COG1218	3'(2'),5'-bisphosphate nucleotidase
AHML_02995	COG0814	amino acid
AHML_03000	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AHML_03005	COG3708	Transcriptional regulator
AHML_03005	COG2207	Transcriptional regulator
AHML_03015	COG0626	cystathionine gamma-synthase activity
AHML_03020	COG0527	aspartate kinase activity
AHML_03020	COG0460	homoserine dehydrogenase
AHML_03030	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
AHML_03040	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
AHML_03045	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
AHML_03055	COG0137	argininosuccinate synthase activity
AHML_03060	COG0165	Argininosuccinate lyase
AHML_03085	COG0110	maltose O-acetyltransferase activity
AHML_03090	COG3174	membrane
AHML_03095	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
AHML_03105	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
AHML_03110	COG4208	sulfate ABC transporter
AHML_03115	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
AHML_03120	COG0583	DNA-binding transcription factor activity
AHML_03125	COG3397	chitin binding
AHML_03130	COG0840	transmembrane signaling receptor activity
AHML_03160	COG4946	Tricorn protease homolog
AHML_03160	COG0793	Belongs to the peptidase S41A family
AHML_03180	COG1328	CTP reductase activity
AHML_03185	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
AHML_03205	COG1448	Aminotransferase
AHML_03250	COG0513	Belongs to the DEAD box helicase family
AHML_03265	COG3568	Endonuclease Exonuclease Phosphatase
AHML_03270	COG0840	transmembrane signaling receptor activity
AHML_03285	COG3112	Uncharacterised protein family (UPF0231)
AHML_03290	COG3835	regulator
AHML_03295	COG2610	gluconate transmembrane transporter activity
AHML_03300	COG1929	Belongs to the glycerate kinase type-1 family
AHML_03315	COG0583	DNA-binding transcription factor activity
AHML_03320	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
AHML_03335	COG0347	Belongs to the P(II) protein family
AHML_03340	COG1840	ABC-type Fe3 transport system, periplasmic component
AHML_03350	COG3842	ATPase activity
AHML_03355	COG2837	iron assimilation
AHML_03360	COG1438	arginine binding
AHML_03365	COG1126	abc transporter atp-binding protein
AHML_03370	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AHML_03375	COG4215	(ABC) transporter
AHML_03380	COG4160	amino acid transport
AHML_03385	COG0039	L-malate dehydrogenase activity
AHML_03390	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
AHML_03395	COG1017	nitric oxide dioxygenase activity
AHML_03395	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AHML_03405	COG4536	flavin adenine dinucleotide binding
AHML_03410	COG4137	Cytochrome C assembly protein
AHML_03415	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
AHML_03420	COG0228	four-way junction DNA binding
AHML_03425	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
AHML_03430	COG0336	Belongs to the RNA methyltransferase TrmD family
AHML_03435	COG0335	large ribosomal subunit rRNA binding
AHML_03445	COG3066	DNA modification
AHML_03450	COG1051	belongs to the nudix hydrolase family
AHML_03460	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
AHML_03465	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
AHML_03470	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
AHML_03480	COG0583	DNA-binding transcription factor activity
AHML_03485	COG0640	Transcriptional regulator
AHML_03490	COG0268	Binds directly to 16S ribosomal RNA
AHML_03495	COG0728	peptidoglycan biosynthetic process
AHML_03500	COG0196	riboflavin kinase activity
AHML_03505	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
AHML_03510	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
AHML_03515	COG1047	Peptidyl-prolyl cis-trans
AHML_03520	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
AHML_03580	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AHML_03580	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
AHML_03595	COG1854	S-ribosylhomocysteine lyase activity
AHML_03600	COG3706	GGDEF domain
AHML_03605	COG0557	exoribonuclease II activity
AHML_03610	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AHML_03620	COG2153	protein acetylation
AHML_03640	COG1914	H( )-stimulated, divalent metal cation uptake system
AHML_03645	COG0360	Binds together with S18 to 16S ribosomal RNA
AHML_03650	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
AHML_03655	COG0359	binds to the 23S rRNA
AHML_03660	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AHML_03685	COG1238	metal cluster binding
AHML_03690	COG0612	Peptidase, M16
AHML_03695	COG2918	glutathione biosynthetic process
AHML_03705	COG1022	Amp-dependent synthetase and ligase
AHML_03715	COG0456	acetyltransferase
AHML_03725	COG0714	Associated with various cellular activities
AHML_03735	COG5001	Diguanylate cyclase
AHML_03740	COG0745	RESPONSE REGULATOR receiver
AHML_03740	COG3706	GGDEF domain
AHML_03770	COG1902	pentaerythritol trinitrate reductase activity
AHML_03785	COG2957	Belongs to the agmatine deiminase family
AHML_03790	COG0154	amidase activity
AHML_03810	COG0513	Belongs to the DEAD box helicase family
AHML_03830	COG1912	Pfam S-adenosyl-l-methionine hydroxide adenosyltransferase
AHML_03835	COG1858	cytochrome C peroxidase
AHML_03860	COG2070	2-Nitropropane dioxygenase
AHML_03870	COG2205	protein histidine kinase activity
AHML_03875	COG0745	RESPONSE REGULATOR receiver
AHML_03880	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AHML_03885	COG0577	efflux transmembrane transporter activity
AHML_03885	COG1136	(ABC) transporter
AHML_03890	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AHML_03895	COG1126	abc transporter atp-binding protein
AHML_03900	COG0765	amino acid transport
AHML_03905	COG0765	amino acid transport
AHML_03910	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
AHML_03915	COG1505	serine-type exopeptidase activity
AHML_03935	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
AHML_03950	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AHML_03955	COG4991	sh3 domain protein
AHML_03970	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
AHML_03975	COG1940	carbohydrate kinase activity
AHML_03980	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
AHML_03985	COG0126	phosphoglycerate kinase activity
AHML_03990	COG0191	fructose-bisphosphate aldolase activity
AHML_03995	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AHML_04030	COG0354	folic acid binding
AHML_04035	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
AHML_04045	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
AHML_04050	COG1595	DNA-templated transcription, initiation
AHML_04070	COG0481	GTPase activity
AHML_04075	COG0681	Belongs to the peptidase S26 family
AHML_04080	COG0571	ribonuclease III activity
AHML_04090	COG1381	Involved in DNA repair and RecF pathway recombination
AHML_04095	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
AHML_04110	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
AHML_04115	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
AHML_04120	COG3716	PTS system mannose fructose sorbose family IID component
AHML_04130	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AHML_04135	COG2222	sugar isomerase
AHML_04145	COG1349	DNA-binding transcription factor activity
AHML_04150	COG3023	N-Acetylmuramoyl-L-alanine amidase
AHML_04155	COG4807	Protein conserved in bacteria
AHML_04165	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
AHML_04170	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
AHML_04175	COG3956	TIGRFAM MazG family protein
AHML_04180	COG0504	CTP synthase activity
AHML_04185	COG0148	phosphopyruvate hydratase activity
AHML_04190	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
AHML_04195	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
AHML_04205	COG0585	pseudouridine synthase activity
AHML_04210	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
AHML_04215	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
AHML_04220	COG1238	metal cluster binding
AHML_04225	COG4942	peptidase
AHML_04225	COG1388	LysM domain
AHML_04235	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
AHML_04240	COG0828	Belongs to the bacterial ribosomal protein bS21 family
AHML_04245	COG1610	YqeY-like protein
AHML_04250	COG0358	DNA primase activity
AHML_04255	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
AHML_04280	COG0151	Belongs to the GarS family
AHML_04285	COG0138	bifunctional purine biosynthesis protein purh
AHML_04295	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
AHML_04300	COG3036	rescue of stalled ribosome
AHML_04305	COG0635	Involved in the biosynthesis of porphyrin-containing compound
AHML_04310	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
AHML_04320	COG0673	inositol 2-dehydrogenase activity
AHML_04330	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AHML_04350	COG0477	Major facilitator Superfamily
AHML_04360	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
AHML_04365	COG1027	Aspartate ammonia-lyase
AHML_04370	COG3030	protein affecting phage T7 exclusion by the F plasmid
AHML_04375	COG0534	Mate efflux family protein
AHML_04380	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
AHML_04385	COG0459	protein refolding
AHML_04395	COG5001	Diguanylate cyclase
AHML_04395	COG3300	MHYT domain
AHML_04405	COG0564	pseudouridine synthase activity
AHML_04410	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
AHML_04420	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AHML_04430	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
AHML_04435	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
AHML_04440	COG1178	ABC-type Fe3 transport system permease component
AHML_04445	COG4143	(ABC) transporter
AHML_04460	COG0066	3-isopropylmalate dehydratase activity
AHML_04465	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
AHML_04470	COG0473	3-isopropylmalate dehydrogenase activity
AHML_04475	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AHML_04485	COG0671	phosphoesterase, PA-phosphatase related
AHML_04500	COG0028	Belongs to the TPP enzyme family
AHML_04510	COG0857	belongs to the CobB CobQ family
AHML_04510	COG0280	phosphate acetyltransferase
AHML_04515	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
AHML_04520	COG3092	negative regulation of chromosome organization
AHML_04525	COG3013	Belongs to the UPF0304 family
AHML_04530	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
AHML_04535	COG2716	regulation of RNA biosynthetic process
AHML_04545	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
AHML_04550	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
AHML_04565	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
AHML_04585	COG0784	Response regulator, receiver
AHML_04585	COG5002	protein histidine kinase activity
AHML_04585	COG2198	Histidine kinase
AHML_04610	COG0840	transmembrane signaling receptor activity
AHML_04620	COG1464	Belongs to the NlpA lipoprotein family
AHML_04625	COG2011	ABC-type metal ion transport system permease component
AHML_04630	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
AHML_04650	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
AHML_04650	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
AHML_04655	COG0802	atpase or kinase
AHML_04665	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
AHML_04670	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
AHML_04675	COG1923	regulation of RNA biosynthetic process
AHML_04680	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
AHML_04685	COG0330	HflC and HflK could
AHML_04690	COG0330	HflC and HflK could
AHML_04695	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
AHML_04700	COG0142	geranyltranstransferase activity
AHML_04705	COG0261	This protein binds to 23S rRNA in the presence of protein L20
AHML_04710	COG0211	Belongs to the bacterial ribosomal protein bL27 family
AHML_04715	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
AHML_04725	COG0318	PFAM AMP-dependent synthetase and ligase
AHML_04740	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
AHML_04745	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AHML_04755	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
AHML_04765	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
AHML_04770	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
AHML_04780	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
AHML_04790	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
AHML_04795	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
AHML_04800	COG2252	PERMEase
AHML_04810	COG0488	(ABC) transporter
AHML_04815	COG0582	viral genome integration into host DNA
AHML_04825	COG0629	single-stranded DNA binding
AHML_04950	COG0464	growth
AHML_05000	COG4626	Terminase
AHML_05000	COG1802	Transcriptional regulator
AHML_05015	COG0616	signal peptide processing
AHML_05105	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
AHML_05110	COG0741	lytic transglycosylase activity
AHML_05130	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
AHML_05135	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
AHML_05140	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
AHML_05165	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AHML_05175	COG3721	Heme iron utilization protein
AHML_05180	COG0748	coenzyme F420 binding
AHML_05200	COG4771	TonB-dependent receptor
AHML_05205	COG2814	Major facilitator Superfamily
AHML_05210	COG3655	Transcriptional regulator
AHML_05220	COG2202	Pas domain
AHML_05220	COG2205	protein histidine kinase activity
AHML_05235	COG3397	chitin binding
AHML_05240	COG2226	methyltransferase
AHML_05245	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AHML_05250	COG1765	OsmC-like protein
AHML_05265	COG3954	Phosphoribulokinase
AHML_05270	COG2076	Multidrug Resistance protein
AHML_05275	COG2076	Multidrug Resistance protein
AHML_05280	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
AHML_05285	COG0726	polysaccharide deacetylase
AHML_05290	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AHML_05290	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
AHML_05295	COG0463	Glycosyl transferase, family 2
AHML_05300	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
AHML_05310	COG3089	Belongs to the UPF0270 family
AHML_05315	COG4251	negative regulation of phosphorylation
AHML_05315	COG2203	Gaf domain
AHML_05315	COG3706	GGDEF domain
AHML_05315	COG5001	Diguanylate cyclase
AHML_05320	COG0429	hydrolase of the alpha beta-hydrolase fold
AHML_05325	COG0784	Response regulator, receiver
AHML_05325	COG0835	chemotaxis
AHML_05335	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
AHML_05340	COG1047	Peptidyl-prolyl cis-trans
AHML_05345	COG2900	Belongs to the SlyX family
AHML_05355	COG0545	Peptidyl-prolyl cis-trans isomerase
AHML_05360	COG2204	response regulator
AHML_05380	COG0737	Belongs to the 5'-nucleotidase family
AHML_05385	COG2200	EAL domain
AHML_05400	COG0305	Participates in initiation and elongation during chromosome replication
AHML_05405	COG0305	Participates in initiation and elongation during chromosome replication
AHML_05410	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
AHML_05415	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
AHML_05425	COG2203	Gaf domain
AHML_05425	COG2200	EAL domain
AHML_05425	COG2199	diguanylate cyclase activity
AHML_05440	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
AHML_05445	COG2201	protein-glutamate methylesterase activity
AHML_05450	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
AHML_05460	COG0840	transmembrane signaling receptor activity
AHML_05465	COG0835	chemotaxis
AHML_05475	COG0643	Histidine kinase
AHML_05475	COG2198	Histidine kinase
AHML_05485	COG0745	RESPONSE REGULATOR receiver
AHML_05490	COG0840	transmembrane signaling receptor activity
AHML_05505	COG1280	lysine exporter protein (LysE YggA)
AHML_05510	COG0826	peptidase U32
AHML_05520	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
AHML_05535	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
AHML_05560	COG0300	oxidoreductase activity
AHML_05570	COG0840	transmembrane signaling receptor activity
AHML_05575	COG0697	spore germination
AHML_05580	COG2133	pyrroloquinoline quinone binding
AHML_05615	COG2226	methyltransferase
AHML_05675	COG4771	TonB-dependent receptor
AHML_05710	COG0514	ATP-dependent DNA helicase (RecQ)
AHML_05750	COG0720	synthase
AHML_05765	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
AHML_05770	COG0602	queuosine metabolic process
AHML_05780	COG2003	Belongs to the UPF0758 family
AHML_05825	COG5377	YqaJ viral recombinase family
AHML_05850	COG0077	Prephenate dehydratase
AHML_05850	COG1605	Chorismate mutase
AHML_05880	COG3272	Protein of unknown function (DUF1722)
AHML_05885	COG0789	Transcriptional regulator
AHML_05890	COG0415	Belongs to the DNA photolyase family
AHML_05900	COG4221	oxidoreductase activity
AHML_05915	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
AHML_05940	COG0783	Belongs to the Dps family
AHML_05945	COG1151	hydroxylamine reductase activity
AHML_05955	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
AHML_05960	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
AHML_05960	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
AHML_05965	COG2771	luxR family
AHML_05975	COG3501	Rhs element vgr protein
AHML_06010	COG0693	protein deglycase activity
AHML_06015	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
AHML_06020	COG1666	GTP binding
AHML_06025	COG3248	Nucleoside-binding outer membrane protein
AHML_06030	COG2211	Major facilitator Superfamily
AHML_06040	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
AHML_06050	COG2813	Specifically methylates the guanine in position
AHML_06055	COG0271	Belongs to the BolA IbaG family
AHML_06060	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
AHML_06065	COG1805	sodium ion transport
AHML_06070	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
AHML_06075	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
AHML_06080	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
AHML_06085	COG2871	sodium ion transport
AHML_06090	COG1477	protein flavinylation
AHML_06105	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
AHML_06110	COG0840	transmembrane signaling receptor activity
AHML_06115	COG0583	DNA-binding transcription factor activity
AHML_06125	COG2363	Small membrane protein
AHML_06130	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
AHML_06140	COG0473	3-isopropylmalate dehydrogenase activity
AHML_06145	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AHML_06150	COG1611	Belongs to the LOG family
AHML_06155	COG3706	GGDEF domain
AHML_06165	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
AHML_06165	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
AHML_06175	COG5595	Zn-ribbon-containing, possibly nucleic-acid-binding protein (DUF2310)
AHML_06200	COG3098	single-species biofilm formation
AHML_06205	COG0564	pseudouridine synthase activity
AHML_06215	COG4580	involved in the transport of maltose and maltodextrins
AHML_06225	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AHML_06225	COG1263	PTS System
AHML_06235	COG2171	N-acyltransferase activity
AHML_06240	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
AHML_06245	COG0024	Methionine aminopeptidase
AHML_06250	COG0052	Belongs to the universal ribosomal protein uS2 family
AHML_06255	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
AHML_06260	COG0528	UMP kinase activity
AHML_06265	COG0233	cytoplasmic translational termination
AHML_06275	COG0575	Belongs to the CDS family
AHML_06280	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
AHML_06285	COG0750	zinc metalloprotease
AHML_06300	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AHML_06305	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
AHML_06310	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AHML_06315	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AHML_06320	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
AHML_06330	COG0825	malonyl-CoA metabolic process
AHML_06335	COG3710	Transcriptional regulator
AHML_06340	COG0531	amino acid
AHML_06345	COG1982	Orn Lys Arg decarboxylase major
AHML_06350	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
AHML_06365	COG0814	amino acid
AHML_06380	COG0531	amino acid
AHML_06390	COG0488	(ABC) transporter
AHML_06400	COG3590	peptidase
AHML_06405	COG0037	tRNA processing
AHML_06410	COG3706	GGDEF domain
AHML_06445	COG0366	Alpha amylase catalytic
AHML_06460	COG0463	Glycosyl transferase, family 2
AHML_06475	COG2989	Protein conserved in bacteria
AHML_06480	COG3108	Peptidase M15
AHML_06490	COG2860	membrane
AHML_06500	COG1196	nuclear chromosome segregation
AHML_06505	COG3115	cell septum assembly
AHML_06510	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
AHML_06520	COG1328	CTP reductase activity
AHML_06525	COG0602	queuosine metabolic process
AHML_06555	COG1566	PFAM secretion protein HlyD family protein
AHML_06560	COG1846	Transcriptional regulator
AHML_06570	COG0281	malic enzyme
AHML_06575	COG3290	protein histidine kinase activity
AHML_06580	COG4565	transcriptional regulatory protein
AHML_06585	COG0697	spore germination
AHML_06595	COG1012	belongs to the aldehyde dehydrogenase family
AHML_06600	COG3284	Transcriptional regulator
AHML_06605	COG1960	acyl-CoA dehydrogenase activity
AHML_06610	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AHML_06615	COG0346	lactoylglutathione lyase activity
AHML_06620	COG0745	RESPONSE REGULATOR receiver
AHML_06625	COG5002	protein histidine kinase activity
AHML_06635	COG4783	chaperone-mediated protein folding
AHML_06650	COG3142	Participates in the control of copper homeostasis
AHML_06655	COG0545	Peptidyl-prolyl cis-trans isomerase
AHML_06660	COG1131	(ABC) transporter
AHML_06680	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
AHML_06690	COG0678	peroxiredoxin activity
AHML_06700	COG0019	diaminopimelate decarboxylase activity
AHML_06705	COG1115	amino acid carrier protein
AHML_06710	COG0095	Lipoate-protein ligase
AHML_06715	COG2233	PERMEase
AHML_06720	COG0745	RESPONSE REGULATOR receiver
AHML_06720	COG3706	GGDEF domain
AHML_06730	COG0534	Mate efflux family protein
AHML_06740	COG0281	malic enzyme
AHML_06775	COG0733	neurotransmitter:sodium symporter activity
AHML_06780	COG1752	Esterase of the alpha-beta hydrolase superfamily
AHML_06785	COG2199	diguanylate cyclase activity
AHML_06785	COG2203	Gaf domain
AHML_06790	COG1566	PFAM secretion protein HlyD family protein
AHML_06795	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AHML_06805	COG1032	radical SAM domain protein
AHML_06825	COG0673	inositol 2-dehydrogenase activity
AHML_06835	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
AHML_06840	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
AHML_06845	COG0739	heme binding
AHML_06845	COG0741	lytic transglycosylase activity
AHML_06845	COG1196	nuclear chromosome segregation
AHML_06850	COG0366	Alpha amylase catalytic
AHML_06870	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AHML_06880	COG0788	formyltetrahydrofolate deformylase activity
AHML_06885	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
AHML_06895	COG3118	belongs to the thioredoxin family
AHML_06900	COG2091	lysine biosynthetic process via aminoadipic acid
AHML_06905	COG0791	NLP P60 protein
AHML_06910	COG3129	Specifically methylates the adenine in position 1618 of 23S rRNA
AHML_06925	COG1376	ErfK ybiS ycfS ynhG family protein
AHML_06925	COG1388	LysM domain
AHML_06930	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
AHML_06995	COG2003	Belongs to the UPF0758 family
AHML_07070	COG3311	Transcriptional regulator
AHML_07080	COG0582	viral genome integration into host DNA
AHML_07085	COG0747	negative chemotaxis
AHML_07095	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AHML_07100	COG4172	Belongs to the ABC transporter superfamily
AHML_07120	COG1070	Carbohydrate kinase
AHML_07130	COG0738	Major facilitator superfamily
AHML_07135	COG1349	DNA-binding transcription factor activity
AHML_07140	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
AHML_07145	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AHML_07150	COG1737	Transcriptional regulator
AHML_07155	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
AHML_07165	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AHML_07170	COG2731	YhcH YjgK YiaL family protein
AHML_07175	COG4409	exo-alpha-(2->6)-sialidase activity
AHML_07215	COG4869	propanediol catabolic process
AHML_07225	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
AHML_07230	COG1882	Formate acetyltransferase
AHML_07235	COG1454	alcohol dehydrogenase
AHML_07235	COG1012	belongs to the aldehyde dehydrogenase family
AHML_07245	COG1012	belongs to the aldehyde dehydrogenase family
AHML_07245	COG1454	alcohol dehydrogenase
AHML_07250	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
AHML_07255	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
AHML_07260	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
AHML_07280	COG0583	DNA-binding transcription factor activity
AHML_07285	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
AHML_07290	COG0243	molybdopterin cofactor binding
AHML_07295	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
AHML_07305	COG1960	acyl-CoA dehydrogenase activity
AHML_07310	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AHML_07320	COG0469	pyruvate kinase activity
AHML_07325	COG1737	Transcriptional regulator
AHML_07340	COG0745	RESPONSE REGULATOR receiver
AHML_07345	COG2274	protein secretion by the type I secretion system
AHML_07355	COG2274	protein secretion by the type I secretion system
AHML_07365	COG2994	toxin metabolic process
AHML_07370	COG3064	Membrane
AHML_07370	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
AHML_07370	COG1073	alpha beta
AHML_07380	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
AHML_07395	COG1677	Flagellar hook-basal body complex protein FliE
AHML_07405	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
AHML_07455	COG1987	bacterial-type flagellum assembly
AHML_07460	COG1684	flagellar biosynthetic protein fliR
AHML_07470	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
AHML_07480	COG0455	bacterial-type flagellum organization
AHML_07495	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
AHML_07500	COG0643	Histidine kinase
AHML_07500	COG2198	Histidine kinase
AHML_07505	COG2201	protein-glutamate methylesterase activity
AHML_07510	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
AHML_07515	COG1360	Flagellar Motor Protein
AHML_07520	COG1192	Involved in chromosome partitioning
AHML_07530	COG0835	chemotaxis
AHML_07545	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
AHML_07550	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
AHML_07555	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
AHML_07560	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
AHML_07565	COG1138	Cytochrome C-type biogenesis protein
AHML_07570	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AHML_07575	COG4235	cytochrome complex assembly
AHML_07575	COG3088	subunit of a heme lyase
AHML_07580	COG3088	subunit of a heme lyase
AHML_07580	COG4235	cytochrome complex assembly
AHML_07595	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
AHML_07600	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
AHML_07600	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
AHML_07615	COG0259	pyridoxamine-phosphate oxidase activity
AHML_07620	COG0625	glutathione transferase activity
AHML_07630	COG3153	acetyltransferase
AHML_07640	COG2850	peptidyl-arginine hydroxylation
AHML_07645	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
AHML_07650	COG2915	High frequency lysogenization protein hflD homolog
AHML_07655	COG0482	sulfurtransferase activity
AHML_07665	COG1187	pseudouridine synthase activity
AHML_07675	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AHML_07685	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AHML_07685	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
AHML_07685	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AHML_07705	COG0456	acetyltransferase
AHML_07720	COG1609	Transcriptional regulator
AHML_07725	COG1263	PTS System
AHML_07725	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AHML_07730	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
AHML_07740	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AHML_07760	COG2207	Transcriptional regulator
AHML_07765	COG0538	isocitrate dehydrogenase activity
AHML_07775	COG3048	D-serine ammonia-lyase activity
AHML_07780	COG2610	gluconate transmembrane transporter activity
AHML_07785	COG0583	DNA-binding transcription factor activity
AHML_07880	COG5566	PFAM Mor transcription activator
AHML_07920	COG0640	Transcriptional regulator
AHML_07930	COG4373	Mu-like prophage FluMu protein gp28
AHML_07935	COG4383	Mu-like prophage protein gp29
AHML_07955	COG4388	Caudovirus prohead serine protease
AHML_07960	COG4397	Mu-like prophage major head subunit gpT
AHML_08040	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
AHML_08045	COG2867	negative regulation of translational initiation
AHML_08055	COG0702	epimerase
AHML_08060	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AHML_08090	COG4964	Belongs to the GSP D family
AHML_08140	COG1454	alcohol dehydrogenase
AHML_08150	COG0564	pseudouridine synthase activity
AHML_08155	COG1957	nucleoside hydrolase
AHML_08180	COG1280	lysine exporter protein (LysE YggA)
AHML_08200	COG3263	regulation of cellular component size
AHML_08210	COG1876	peptidase activity
AHML_08215	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AHML_08220	COG1393	Belongs to the ArsC family
AHML_08225	COG0583	DNA-binding transcription factor activity
AHML_08235	COG3069	C4-dicarboxylate transmembrane transporter activity
AHML_08250	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
AHML_08255	COG0017	Asparaginyl-tRNA synthetase
AHML_08275	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
AHML_08280	COG0156	8-amino-7-oxononanoate synthase activity
AHML_08285	COG2226	methyltransferase
AHML_08285	COG1073	alpha beta
AHML_08290	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
AHML_08295	COG0501	Belongs to the peptidase M48B family
AHML_08305	COG0633	Ferredoxin
AHML_08305	COG3217	Mosc domain protein beta barrel domain protein
AHML_08305	COG3217	Mosc domain protein beta barrel domain protein
AHML_08305	COG0633	Ferredoxin
AHML_08315	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
AHML_08315	COG0674	pyruvate-flavodoxin oxidoreductase activity
AHML_08315	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
AHML_08315	COG1013	pyruvate-flavodoxin oxidoreductase activity
AHML_08320	COG2366	antibiotic biosynthetic process
AHML_08340	COG0534	Mate efflux family protein
AHML_08380	COG1309	transcriptional regulator
AHML_08395	COG0791	NLP P60 protein
AHML_08405	COG0583	DNA-binding transcription factor activity
AHML_08410	COG0450	alkyl hydroperoxide reductase
AHML_08430	COG0500	methyltransferase
AHML_08435	COG4106	trans-aconitate 2-methyltransferase activity
AHML_08440	COG1801	Protein of unknown function DUF72
AHML_08445	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
AHML_08450	COG0217	transcriptional regulatory protein
AHML_08455	COG2194	sulfuric ester hydrolase activity
AHML_08465	COG1940	carbohydrate kinase activity
AHML_08465	COG1846	Transcriptional regulator
AHML_08470	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
AHML_08475	COG0363	glucosamine-6-phosphate deaminase activity
AHML_08480	COG1263	PTS System
AHML_08480	COG2190	(PTS) system
AHML_08480	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AHML_08490	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AHML_08495	COG0735	belongs to the Fur family
AHML_08505	COG0716	FMN binding
AHML_08520	COG0596	Alpha beta hydrolase
AHML_08525	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
AHML_08530	COG0033	Phosphoglucomutase
AHML_08540	COG1846	Transcriptional regulator
AHML_08545	COG2951	lytic endotransglycosylase activity
AHML_08550	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
AHML_08555	COG4136	ATPase activity
AHML_08565	COG4134	Bacterial extracellular solute-binding protein
AHML_08575	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AHML_08585	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AHML_08590	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AHML_08600	COG0729	surface antigen
AHML_08615	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
AHML_08625	COG0741	lytic transglycosylase activity
AHML_08640	COG1607	acyl-coa hydrolase
AHML_08650	COG3021	interspecies interaction between organisms
AHML_08655	COG1388	LysM domain
AHML_08655	COG0741	lytic transglycosylase activity
AHML_08660	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AHML_08665	COG2226	methyltransferase
AHML_08670	COG0328	RNA-DNA hybrid ribonuclease activity
AHML_08675	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
AHML_08685	COG3437	response regulator, receiver
AHML_08685	COG0784	Response regulator, receiver
AHML_08690	COG1960	acyl-CoA dehydrogenase activity
AHML_08695	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
AHML_08700	COG0121	glutamine amidotransferase
AHML_08730	COG2197	response regulator
AHML_08735	COG3850	Histidine kinase
AHML_08740	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
AHML_08745	COG1149	4fe-4S ferredoxin, iron-sulfur binding domain protein
AHML_08745	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
AHML_08755	COG0243	molybdopterin cofactor binding
AHML_08760	COG0437	4 iron, 4 sulfur cluster binding
AHML_08765	COG0348	domain, Protein
AHML_08775	COG3005	denitrification pathway
AHML_08780	COG0521	Mo-molybdopterin cofactor biosynthetic process
AHML_08785	COG0315	cyclic pyranopterin monophosphate synthase activity
AHML_08790	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
AHML_08795	COG0314	molybdopterin synthase activity
AHML_08810	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
AHML_08815	COG2267	carboxylic ester hydrolase activity
AHML_08820	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
AHML_08830	COG0302	gtp cyclohydrolase
AHML_08835	COG0840	transmembrane signaling receptor activity
AHML_08840	COG2759	Belongs to the formate--tetrahydrofolate ligase family
AHML_08850	COG0583	DNA-binding transcription factor activity
AHML_08880	COG2195	Cleaves the N-terminal amino acid of tripeptides
AHML_08885	COG1166	arginine decarboxylase activity
AHML_08900	COG0814	amino acid
AHML_08910	COG3681	Belongs to the UPF0597 family
AHML_08915	COG2964	Protein conserved in bacteria
AHML_08925	COG1061	Type III restriction enzyme res subunit
AHML_08955	COG1187	pseudouridine synthase activity
AHML_08960	COG2807	transmembrane transport
AHML_08970	COG0583	DNA-binding transcription factor activity
AHML_08975	COG2271	Major facilitator Superfamily
AHML_09000	COG2979	Protein of unknown function (DUF533)
AHML_09010	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AHML_09020	COG1294	oxidase, subunit
AHML_09030	COG2814	Major facilitator Superfamily
AHML_09035	COG0656	L-ascorbic acid biosynthetic process
AHML_09055	COG0583	DNA-binding transcription factor activity
AHML_09060	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
AHML_09065	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
AHML_09070	COG2271	Major facilitator Superfamily
AHML_09075	COG1349	DNA-binding transcription factor activity
AHML_09085	COG0584	glycerophosphoryl diester phosphodiesterase
AHML_09090	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
AHML_09095	COG0287	Prephenate dehydrogenase
AHML_09095	COG1605	Chorismate mutase
AHML_09100	COG0583	DNA-binding transcription factor activity
AHML_09105	COG3085	chromosome segregation
AHML_09110	COG4574	serine-type endopeptidase inhibitor activity
AHML_09130	COG1770	oligopeptidase
AHML_09135	COG4771	TonB-dependent receptor
AHML_09140	COG3083	sulfuric ester hydrolase activity
AHML_09145	COG3082	Protein of unknown function (DUF1414)
AHML_09150	COG3081	Nucleoid-associated protein
AHML_09160	COG1175	transmembrane transport
AHML_09170	COG3842	ATPase activity
AHML_09195	COG0425	Belongs to the sulfur carrier protein TusA family
AHML_09200	COG4783	chaperone-mediated protein folding
AHML_09210	COG1393	Belongs to the ArsC family
AHML_09230	COG3124	Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP
AHML_09235	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
AHML_09240	COG2431	L-lysine efflux transmembrane transporter activity
AHML_09250	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AHML_09255	COG4215	(ABC) transporter
AHML_09270	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
AHML_09280	COG0446	pyridine nucleotide-disulphide oxidoreductase
AHML_09295	COG1566	PFAM secretion protein HlyD family protein
AHML_09300	COG1538	Outer membrane efflux protein
AHML_09305	COG0628	permease
AHML_09310	COG1473	amidohydrolase
AHML_09315	COG2373	Large extracellular alpha-helical protein
AHML_09320	COG4953	penicillin-binding protein 1C
AHML_09330	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AHML_09330	COG0301	tRNA thio-modification
AHML_09365	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
AHML_09410	COG2089	acid synthase
AHML_09420	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
AHML_09440	COG1086	Polysaccharide biosynthesis protein
AHML_09455	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
AHML_09475	COG0483	inositol monophosphate 1-phosphatase activity
AHML_09485	COG0625	glutathione transferase activity
AHML_09490	COG2814	Major facilitator Superfamily
AHML_09505	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AHML_09510	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AHML_09515	COG0404	The glycine cleavage system catalyzes the degradation of glycine
AHML_09520	COG0509	glycine decarboxylation via glycine cleavage system
AHML_09525	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
AHML_09525	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
AHML_09530	COG0640	Transcriptional regulator
AHML_09535	COG0798	PFAM Bile acid sodium symporter
AHML_09540	COG1393	Belongs to the ArsC family
AHML_09555	COG2814	Major facilitator Superfamily
AHML_09560	COG3634	alkyl hydroperoxide reductase activity
AHML_09565	COG0450	alkyl hydroperoxide reductase
AHML_09570	COG0517	IMP dehydrogenase activity
AHML_09575	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
AHML_09580	COG0343	queuine tRNA-ribosyltransferase activity
AHML_09585	COG1862	Preprotein translocase
AHML_09590	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AHML_09595	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AHML_09645	COG1104	cysteine desulfurase activity
AHML_09650	COG0822	iron-sulfur transferase activity
AHML_09660	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
AHML_09665	COG0443	Heat shock 70 kDa protein
AHML_09670	COG0633	Ferredoxin
AHML_09680	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
AHML_09685	COG0105	UTP biosynthetic process
AHML_09690	COG0820	rRNA (adenine-C2-)-methyltransferase activity
AHML_09705	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
AHML_09710	COG0124	histidyl-tRNA synthetase
AHML_09715	COG2976	Protein conserved in bacteria
AHML_09720	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AHML_09725	COG1160	GTP binding
AHML_09730	COG1645	bacterial-type flagellum-dependent swarming motility
AHML_09735	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
AHML_09740	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
AHML_09740	COG0047	phosphoribosylformylglycinamidine synthase activity
AHML_09750	COG1007	ATP synthesis coupled electron transport
AHML_09755	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AHML_09765	COG0713	ATP synthesis coupled electron transport
AHML_09770	COG0839	Belongs to the complex I subunit 6 family
AHML_09775	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AHML_09780	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
AHML_09785	COG1034	ATP synthesis coupled electron transport
AHML_09800	COG0649	NAD binding
AHML_09800	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AHML_09805	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AHML_09810	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AHML_09815	COG1360	Flagellar Motor Protein
AHML_09820	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
AHML_09830	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
AHML_09850	COG0724	RNA recognition motif
AHML_09855	COG4989	oxidoreductase activity
AHML_09880	COG3437	response regulator, receiver
AHML_09885	COG0583	DNA-binding transcription factor activity
AHML_09900	COG3300	MHYT domain
AHML_09900	COG5001	Diguanylate cyclase
AHML_09905	COG0778	Nitroreductase
AHML_09925	COG0583	DNA-binding transcription factor activity
AHML_09935	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
AHML_09940	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
AHML_09945	COG0539	negative regulation of cytoplasmic translation
AHML_09950	COG0776	regulation of translation
AHML_09960	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
AHML_09980	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
AHML_09985	COG0602	queuosine metabolic process
AHML_09990	COG3530	Putative quorum-sensing-regulated virulence factor
AHML_09995	COG2096	Adenosyltransferase
AHML_10000	COG2916	Histone family protein nucleoid-structuring protein H-NS
AHML_10005	COG1757	Na H antiporter
AHML_10010	COG1435	thymidine kinase activity
AHML_10030	COG3501	Rhs element vgr protein
AHML_10035	COG3179	chitinase
AHML_10045	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
AHML_10050	COG1278	Cold shock
AHML_10055	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
AHML_10060	COG0542	response to heat
AHML_10065	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
AHML_10070	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
AHML_10075	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
AHML_10080	COG3134	Outer membrane lipoprotein
AHML_10085	COG3706	GGDEF domain
AHML_10090	COG0492	ferredoxin-NADP+ reductase activity
AHML_10100	COG1674	ftsk spoiiie
AHML_10100	COG0531	amino acid
AHML_10105	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
AHML_10110	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
AHML_10115	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
AHML_10120	COG1286	toxin biosynthetic process
AHML_10125	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
AHML_10135	COG4172	Belongs to the ABC transporter superfamily
AHML_10145	COG4171	peptide transport system, permease
AHML_10150	COG4168	peptide transport system, permease
AHML_10160	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
AHML_10165	COG1842	Phage shock protein A
AHML_10180	COG3106	COG3106 Predicted ATPase
AHML_10185	COG3768	UPF0283 membrane protein
AHML_10195	COG2154	pterin-4-alpha-carbinolamine dehydratase
AHML_10200	COG2154	pterin-4-alpha-carbinolamine dehydratase
AHML_10215	COG2199	diguanylate cyclase activity
AHML_10220	COG2885	chlorophyll binding
AHML_10225	COG0861	Integral membrane protein TerC family
AHML_10240	COG1022	Amp-dependent synthetase and ligase
AHML_10245	COG0295	cytidine deaminase activity
AHML_10250	COG1346	cytolysis
AHML_10255	COG1380	Effector of murein hydrolase LrgA
AHML_10260	COG3345	alpha-galactosidase
AHML_10270	COG2925	Exonuclease
AHML_10275	COG2160	L-arabinose isomerase activity
AHML_10285	COG1069	ribulokinase activity
AHML_10290	COG1879	ABC-type sugar transport system periplasmic component
AHML_10300	COG1172	Belongs to the binding-protein-dependent transport system permease family
AHML_10310	COG0583	DNA-binding transcription factor activity
AHML_10320	COG0257	Belongs to the bacterial ribosomal protein bL36 family
AHML_10325	COG0254	rRNA binding
AHML_10340	COG1451	nucleotide metabolic process
AHML_10355	COG3069	C4-dicarboxylate transmembrane transporter activity
AHML_10365	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
AHML_10365	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AHML_10370	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AHML_10395	COG2009	succinate dehydrogenase
AHML_10400	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
AHML_10405	COG1053	succinate dehydrogenase
AHML_10415	COG0567	Dehydrogenase, E1 component
AHML_10420	COG0508	dehydrogenase complex catalyzes the overall conversion of
AHML_10425	COG0045	succinate-CoA ligase (ADP-forming) activity
AHML_10430	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
AHML_10440	COG2983	Belongs to the UPF0260 family
AHML_10445	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AHML_10455	COG3842	ATPase activity
AHML_10460	COG1840	ABC-type Fe3 transport system, periplasmic component
AHML_10470	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
AHML_10480	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AHML_10485	COG1882	Formate acetyltransferase
AHML_10490	COG2116	formate transmembrane transporter activity
AHML_10495	COG1944	ATP diphosphatase activity
AHML_10500	COG2076	Multidrug Resistance protein
AHML_10505	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
AHML_10510	COG0612	Peptidase, M16
AHML_10515	COG0626	cystathionine gamma-synthase activity
AHML_10525	COG2910	NAD(P)H-binding
AHML_10530	COG0583	DNA-binding transcription factor activity
AHML_10540	COG4977	sequence-specific DNA binding
AHML_10545	COG4774	siderophore transport
AHML_10555	COG0583	DNA-binding transcription factor activity
AHML_10560	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
AHML_10585	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AHML_10590	COG3046	protein related to deoxyribodipyrimidine photolyase
AHML_10600	COG3033	Beta-eliminating lyase
AHML_10610	COG1051	belongs to the nudix hydrolase family
AHML_10615	COG3088	subunit of a heme lyase
AHML_10615	COG4235	cytochrome complex assembly
AHML_10625	COG1138	Cytochrome C-type biogenesis protein
AHML_10630	COG3301	Polysulphide reductase, NrfD
AHML_10635	COG0437	4 iron, 4 sulfur cluster binding
AHML_10640	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
AHML_10660	COG0247	lactate metabolic process
AHML_10665	COG3075	Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses fumarate or nitrate as electron acceptor
AHML_10670	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
AHML_10675	COG3012	SEC-C Motif Domain Protein
AHML_10680	COG0840	transmembrane signaling receptor activity
AHML_10685	COG1846	Transcriptional regulator
AHML_10685	COG1940	carbohydrate kinase activity
AHML_10690	COG3290	protein histidine kinase activity
AHML_10695	COG4565	transcriptional regulatory protein
AHML_10715	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
AHML_10720	COG0569	domain protein
AHML_10720	COG2985	domain, Protein
AHML_10725	COG0556	nucleotide-excision repair
AHML_10735	COG0586	Pfam SNARE associated Golgi protein
AHML_10740	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
AHML_10745	COG3067	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
AHML_10750	COG2186	Transcriptional regulator
AHML_10755	COG2719	SpoVR family
AHML_10765	COG2766	serine protein kinase
AHML_10770	COG0514	ATP-dependent DNA helicase (RecQ)
AHML_10775	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
AHML_10780	COG0814	amino acid
AHML_10810	COG0058	SHG alpha-glucan phosphorylase activity
AHML_10815	COG0471	metal ion transport
AHML_10820	COG3118	belongs to the thioredoxin family
AHML_10830	COG1132	(ABC) transporter
AHML_10840	COG1132	(ABC) transporter
AHML_10850	COG2501	S4 domain
AHML_10860	COG3243	poly(R)-hydroxyalkanoic acid synthase
AHML_10880	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
AHML_10885	COG2329	Antibiotic biosynthesis monooxygenase
AHML_10915	COG1742	UPF0060 membrane protein
AHML_10925	COG0456	acetyltransferase
AHML_10930	COG0513	Belongs to the DEAD box helicase family
AHML_10935	COG0386	Belongs to the glutathione peroxidase family
AHML_10945	COG1181	Belongs to the D-alanine--D-alanine ligase family
AHML_10965	COG0730	response to heat
AHML_10970	COG0583	DNA-binding transcription factor activity
AHML_10985	COG3593	DNA synthesis involved in DNA repair
AHML_11000	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
AHML_11005	COG1011	Hydrolase
AHML_11010	COG1473	amidohydrolase
AHML_11015	COG0205	6-phosphofructokinase activity
AHML_11025	COG1434	Gram-negative-bacterium-type cell wall biogenesis
AHML_11030	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
AHML_11040	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
AHML_11045	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
AHML_11065	COG0242	peptide deformylase activity
AHML_11080	COG0384	phenazine biosynthesis protein PhzF
AHML_11100	COG2824	Alkylphosphonate utilization operon protein PhnA
AHML_11125	COG0588	phosphoglycerate mutase activity
AHML_11130	COG3706	GGDEF domain
AHML_11140	COG2840	Smr protein MutS2
AHML_11145	COG2890	protein-(glutamine-N5) methyltransferase activity
AHML_11150	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
AHML_11160	COG0513	Belongs to the DEAD box helicase family
AHML_11170	COG5654	RES domain protein
AHML_11180	COG0814	amino acid
AHML_11185	COG1609	Transcriptional regulator
AHML_11190	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
AHML_11190	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
AHML_11195	COG1105	Belongs to the carbohydrate kinase PfkB family
AHML_11200	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AHML_11200	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AHML_11200	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
AHML_11205	COG2140	Oxalate decarboxylase
AHML_11210	COG1609	Transcriptional regulator
AHML_11225	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AHML_11225	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
AHML_11230	COG3715	PTS system
AHML_11235	COG3716	PTS system mannose fructose sorbose family IID component
AHML_11240	COG2942	2-epimerase
AHML_11245	COG3313	Fe-S protein
AHML_11250	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
AHML_11255	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AHML_11260	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AHML_11265	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AHML_11275	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
AHML_11300	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
AHML_11305	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
AHML_11310	COG0291	Belongs to the bacterial ribosomal protein bL35 family
AHML_11315	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
AHML_11320	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
AHML_11325	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AHML_11325	COG0072	phenylalanine-tRNA ligase activity
AHML_11330	COG0776	regulation of translation
AHML_11350	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
AHML_11360	COG2199	diguanylate cyclase activity
AHML_11365	COG1609	Transcriptional regulator
AHML_11370	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AHML_11375	COG1879	ABC-type sugar transport system periplasmic component
AHML_11380	COG1172	Belongs to the binding-protein-dependent transport system permease family
AHML_11385	COG1129	ABC transporter
AHML_11390	COG1869	D-ribose catabolic process
AHML_11395	COG0625	glutathione transferase activity
AHML_11410	COG0037	tRNA processing
AHML_11415	COG0589	response to stress
AHML_11420	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AHML_11445	COG2010	Cytochrome c
AHML_11460	COG3278	Belongs to the heme-copper respiratory oxidase family
AHML_11470	COG1956	GAF domain-containing protein
AHML_11475	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
AHML_11485	COG0308	aminopeptidase N
AHML_11495	COG2902	Dehydrogenase
AHML_11500	COG0167	dihydroorotate dehydrogenase activity
AHML_11510	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
AHML_11510	COG0116	Belongs to the methyltransferase superfamily
AHML_11520	COG0488	(ABC) transporter
AHML_11535	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
AHML_11540	COG1067	ATP-dependent peptidase activity
AHML_11550	COG3141	response to X-ray
AHML_11560	COG4221	oxidoreductase activity
AHML_11605	COG0372	Belongs to the citrate synthase family
AHML_11610	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
AHML_11620	COG2995	paraquat-inducible protein a
AHML_11625	COG3008	intermembrane lipid transfer
AHML_11630	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
AHML_11630	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
AHML_11645	COG0084	hydrolase, TatD family'
AHML_11650	COG0470	DNA polymerase III
AHML_11655	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
AHML_11660	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
AHML_11665	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
AHML_11670	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AHML_11675	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AHML_11680	COG1028	Short-chain dehydrogenase reductase Sdr
AHML_11690	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AHML_11695	COG0416	fatty acid biosynthetic process
AHML_11700	COG0333	Belongs to the bacterial ribosomal protein bL32 family
AHML_11705	COG1399	metal-binding, possibly nucleic acid-binding protein
AHML_11720	COG2814	Major facilitator Superfamily
AHML_11725	COG0424	maF-like protein
AHML_11740	COG0564	pseudouridine synthase activity
AHML_11745	COG1530	ribonuclease E activity
AHML_11750	COG0306	phosphate transporter
AHML_11755	COG0717	Belongs to the dCTP deaminase family
AHML_11760	COG0572	uridine kinase
AHML_11765	COG0489	protein tyrosine kinase activity
AHML_11770	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AHML_11770	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AHML_11775	COG0625	glutathione transferase activity
AHML_11780	COG1254	Belongs to the acylphosphatase family
AHML_11785	COG0840	transmembrane signaling receptor activity
AHML_11790	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
AHML_11810	COG0709	Synthesizes selenophosphate from selenide and ATP
AHML_11815	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
AHML_11820	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AHML_11825	COG3437	response regulator, receiver
AHML_11835	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
AHML_11845	COG1643	Atp-dependent helicase
AHML_11865	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
AHML_11875	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
AHML_11880	COG2832	Protein of unknown function (DUF454)
AHML_11885	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
AHML_11895	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
AHML_12010	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
AHML_12015	COG0318	PFAM AMP-dependent synthetase and ligase
AHML_12020	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
AHML_12020	COG0596	Alpha beta hydrolase
AHML_12020	COG2226	methyltransferase
AHML_12030	COG1214	PFAM Peptidase M22, glycoprotease
AHML_12035	COG1199	ATP-dependent helicase activity
AHML_12045	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
AHML_12050	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
AHML_12055	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
AHML_12060	COG0131	Imidazoleglycerol-phosphate dehydratase
AHML_12060	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
AHML_12065	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
AHML_12070	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
AHML_12075	COG3437	response regulator, receiver
AHML_12085	COG0784	Response regulator, receiver
AHML_12085	COG2198	Histidine kinase
AHML_12085	COG2205	protein histidine kinase activity
AHML_12090	COG0107	imidazoleglycerol-phosphate synthase activity
AHML_12095	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
AHML_12095	COG0140	phosphoribosyl-ATP diphosphatase activity
AHML_12100	COG0318	PFAM AMP-dependent synthetase and ligase
AHML_12105	COG1288	antiporter activity
AHML_12115	COG3134	Outer membrane lipoprotein
AHML_12125	COG2080	2 iron, 2 sulfur cluster binding
AHML_12130	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
AHML_12135	COG1529	Aldehyde oxidase and xanthine dehydrogenase
AHML_12140	COG2252	PERMEase
AHML_12145	COG0402	S-adenosylhomocysteine deaminase activity
AHML_12150	COG2233	PERMEase
AHML_12155	COG2080	2 iron, 2 sulfur cluster binding
AHML_12155	COG1529	Aldehyde oxidase and xanthine dehydrogenase
AHML_12160	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
AHML_12165	COG0402	S-adenosylhomocysteine deaminase activity
AHML_12170	COG0493	'glutamate synthase
AHML_12170	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
AHML_12185	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
AHML_12185	COG3608	succinylglutamate desuccinylase aspartoacylase
AHML_12190	COG0697	spore germination
AHML_12195	COG0549	Belongs to the carbamate kinase family
AHML_12205	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AHML_12210	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
AHML_12215	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
AHML_12225	COG4388	Caudovirus prohead serine protease
AHML_12240	COG4383	Mu-like prophage protein gp29
AHML_12250	COG4681	YaeQ
AHML_12260	COG1250	3-hydroxyacyl-CoA dehydrogenase
AHML_12260	COG1024	Enoyl-CoA hydratase
AHML_12265	COG0183	Belongs to the thiolase family
AHML_12270	COG0714	Associated with various cellular activities
AHML_12300	COG1595	DNA-templated transcription, initiation
AHML_12325	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
AHML_12345	COG3123	guanosine phosphorylase activity
AHML_12350	COG1760	l-serine dehydratase
AHML_12355	COG1760	l-serine dehydratase
AHML_12360	COG2951	lytic endotransglycosylase activity
AHML_12365	COG3100	YcgL domain-containing protein
AHML_12370	COG0850	regulation of cytokinetic process
AHML_12375	COG2894	cell division
AHML_12380	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
AHML_12390	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AHML_12430	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
AHML_12435	COG0697	spore germination
AHML_12440	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
AHML_12445	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AHML_12455	COG0307	riboflavin synthase, alpha
AHML_12465	COG0534	Mate efflux family protein
AHML_12470	COG0417	DNA replication proofreading
AHML_12495	COG1560	Kdo2-lipid A biosynthetic process
AHML_12500	COG1560	Kdo2-lipid A biosynthetic process
AHML_12510	COG0583	DNA-binding transcription factor activity
AHML_12515	COG0673	inositol 2-dehydrogenase activity
AHML_12520	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
AHML_12525	COG0583	DNA-binding transcription factor activity
AHML_12530	COG1028	Short-chain dehydrogenase reductase Sdr
AHML_12535	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
AHML_12545	COG3300	MHYT domain
AHML_12545	COG5001	Diguanylate cyclase
AHML_12550	COG2723	6-phospho-beta-galactosidase activity
AHML_12555	COG0583	DNA-binding transcription factor activity
AHML_12560	COG3706	GGDEF domain
AHML_12575	COG0667	Aldo Keto reductase
AHML_12580	COG0583	DNA-binding transcription factor activity
AHML_12585	COG0702	epimerase
AHML_12590	COG1506	peptidase
AHML_12590	COG0823	Involved in the tonB-independent uptake of proteins
AHML_12595	COG1073	alpha beta
AHML_12610	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
AHML_12620	COG2003	Belongs to the UPF0758 family
AHML_12635	COG5002	protein histidine kinase activity
AHML_12635	COG5001	Diguanylate cyclase
AHML_12660	COG0730	response to heat
AHML_12670	COG1028	Short-chain dehydrogenase reductase Sdr
AHML_12680	COG1024	Enoyl-CoA hydratase
AHML_12685	COG1024	Enoyl-CoA hydratase
AHML_12690	COG1960	acyl-CoA dehydrogenase activity
AHML_12700	COG1960	acyl-CoA dehydrogenase activity
AHML_12705	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
AHML_12745	COG1584	GPR1 FUN34 yaaH family protein
AHML_12760	COG1115	amino acid carrier protein
AHML_12800	COG1024	Enoyl-CoA hydratase
AHML_12815	COG3162	membrane
AHML_12820	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AHML_12825	COG0488	(ABC) transporter
AHML_12830	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AHML_12835	COG0776	regulation of translation
AHML_12840	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
AHML_12845	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
AHML_12850	COG0740	serine-type endopeptidase activity
AHML_12855	COG0544	peptidyl-prolyl cis-trans isomerase activity
AHML_12865	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
AHML_12870	COG4591	ABC-type transport system involved in lipoprotein release permease component
AHML_12875	COG1136	(ABC) transporter
AHML_12880	COG4591	ABC-type transport system involved in lipoprotein release permease component
AHML_12890	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
AHML_12895	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
AHML_12900	COG4166	transmembrane transport
AHML_12905	COG0697	spore germination
AHML_12915	COG2062	phosphohistidine phosphatase, SixA
AHML_12940	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
AHML_12940	COG2169	Transcriptional regulator
AHML_12990	COG0582	viral genome integration into host DNA
AHML_12995	COG0519	Catalyzes the synthesis of GMP from XMP
AHML_12995	COG0518	GMP synthase (glutamine-hydrolyzing) activity
AHML_13000	COG0516	GMP reductase activity
AHML_13000	COG0517	IMP dehydrogenase activity
AHML_13005	COG3158	transport of potassium into the cell
AHML_13025	COG0697	spore germination
AHML_13030	COG1570	exodeoxyribonuclease VII activity
AHML_13045	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
AHML_13050	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
AHML_13055	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
AHML_13075	COG0598	Magnesium transport protein CorA
AHML_13095	COG4771	TonB-dependent receptor
AHML_13100	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AHML_13105	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AHML_13110	COG1120	ATPase activity
AHML_13115	COG2977	Belongs to the P-Pant transferase superfamily
AHML_13120	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AHML_13125	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AHML_13135	COG1028	Short-chain dehydrogenase reductase Sdr
AHML_13140	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AHML_13145	COG3433	isochorismatase activity
AHML_13145	COG1535	isochorismatase
AHML_13150	COG1021	2,3-dihydroxybenzoate-AMP ligase
AHML_13170	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
AHML_13195	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AHML_13205	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
AHML_13210	COG0563	adenylate kinase activity
AHML_13215	COG0326	Molecular chaperone. Has ATPase activity
AHML_13220	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
AHML_13240	COG3383	formate dehydrogenase (NAD+) activity
AHML_13245	COG3383	formate dehydrogenase (NAD+) activity
AHML_13250	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
AHML_13260	COG3158	transport of potassium into the cell
AHML_13265	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
AHML_13270	COG0651	ATP synthesis coupled electron transport
AHML_13275	COG0650	Formate hydrogenlyase subunit 4
AHML_13280	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
AHML_13280	COG3261	NADH dehydrogenase
AHML_13285	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AHML_13290	COG3260	NADH ubiquinone oxidoreductase 20
AHML_13300	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
AHML_13305	COG1921	L-seryl-tRNASec selenium transferase activity
AHML_13315	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
AHML_13320	COG0298	carbon dioxide binding
AHML_13330	COG0309	Hydrogenase expression formation protein (HypE)
AHML_13335	COG0375	protein maturation
AHML_13345	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
AHML_13350	COG1124	(ABC) transporter
AHML_13355	COG0444	Belongs to the ABC transporter superfamily
AHML_13360	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AHML_13365	COG0601	transmembrane transport
AHML_13370	COG0747	negative chemotaxis
AHML_13375	COG1773	rubredoxin
AHML_13380	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
AHML_13385	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
AHML_13390	COG5557	Pfam Polysulphide reductase, NrfD
AHML_13395	COG0437	4 iron, 4 sulfur cluster binding
AHML_13400	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
AHML_13405	COG0745	RESPONSE REGULATOR receiver
AHML_13415	COG2198	Histidine kinase
AHML_13415	COG0643	Histidine kinase
AHML_13420	COG0840	transmembrane signaling receptor activity
AHML_13420	COG3290	protein histidine kinase activity
AHML_13425	COG0835	chemotaxis
AHML_13435	COG2201	protein-glutamate methylesterase activity
AHML_13445	COG0840	transmembrane signaling receptor activity
AHML_13450	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
AHML_13475	COG2963	transposase activity
AHML_13490	COG4771	TonB-dependent receptor
AHML_13490	COG1629	transport
AHML_13520	COG0659	secondary active sulfate transmembrane transporter activity
AHML_13540	COG0672	)-iron permease
AHML_13560	COG2814	Major facilitator Superfamily
AHML_13570	COG1136	(ABC) transporter
AHML_13595	COG1139	Iron-sulfur cluster binding protein
AHML_13605	COG1620	l-lactate permease
AHML_13610	COG0583	DNA-binding transcription factor activity
AHML_13620	COG0346	lactoylglutathione lyase activity
AHML_13625	COG0596	Alpha beta hydrolase
AHML_13650	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AHML_13655	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
AHML_13655	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
AHML_13660	COG0527	aspartate kinase activity
AHML_13670	COG1368	sulfuric ester hydrolase activity
AHML_13675	COG1619	proteins homologs of microcin C7 resistance protein MccF
AHML_13680	COG4667	esterase of the alpha-beta hydrolase superfamily
AHML_13695	COG2221	Nitrite and sulphite reductase 4Fe-4S
AHML_13700	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
AHML_13700	COG1648	precorrin-2 dehydrogenase activity
AHML_13710	COG0393	Putative heavy-metal-binding
AHML_13730	COG1252	NADH dehydrogenase
AHML_13740	COG2233	PERMEase
AHML_13755	COG2354	Protein conserved in bacteria
AHML_13765	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AHML_13770	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AHML_13805	COG0537	adenosine 5'-monophosphoramidase activity
AHML_13820	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
AHML_13830	COG1301	dicarboxylic acid transport
AHML_13840	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
AHML_13845	COG0861	Integral membrane protein TerC family
AHML_13860	COG0444	Belongs to the ABC transporter superfamily
AHML_13865	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AHML_13870	COG0601	transmembrane transport
AHML_13880	COG2095	MarC family integral membrane protein
AHML_13890	COG1454	alcohol dehydrogenase
AHML_13890	COG1012	belongs to the aldehyde dehydrogenase family
AHML_13895	COG2199	diguanylate cyclase activity
AHML_13895	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
AHML_13900	COG3275	phosphorelay sensor kinase activity
AHML_13905	COG3279	Response regulator of the LytR AlgR family
AHML_13910	COG1966	Carbon starvation protein
AHML_13920	COG1566	PFAM secretion protein HlyD family protein
AHML_13925	COG1061	Type III restriction enzyme res subunit
AHML_13930	COG2027	D-alanyl-D-alanine carboxypeptidase
AHML_13935	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
AHML_13945	COG0436	Aminotransferase
AHML_13950	COG1288	antiporter activity
AHML_13955	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
AHML_13970	COG0697	spore germination
AHML_13975	COG4657	Part of a membrane complex involved in electron transport
AHML_13980	COG2878	Part of a membrane complex involved in electron transport
AHML_13990	COG4658	electron transport chain
AHML_13995	COG4659	FMN binding
AHML_14005	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
AHML_14010	COG0346	lactoylglutathione lyase activity
AHML_14025	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
AHML_14030	COG2056	Na+-H+ antiporter family
AHML_14040	COG2050	protein possibly involved in aromatic compounds catabolism
AHML_14050	COG0247	lactate metabolic process
AHML_14050	COG0277	FAD linked oxidase domain protein
AHML_14060	COG1253	flavin adenine dinucleotide binding
AHML_14065	COG1902	pentaerythritol trinitrate reductase activity
AHML_14070	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
AHML_14075	COG0647	UMP catabolic process
AHML_14080	COG4651	solute:proton antiporter activity
AHML_14080	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
AHML_14090	COG0367	asparagine synthase
AHML_14100	COG0625	glutathione transferase activity
AHML_14105	COG0625	glutathione transferase activity
AHML_14115	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
AHML_14130	COG0564	pseudouridine synthase activity
AHML_14135	COG5001	Diguanylate cyclase
AHML_14140	COG0840	transmembrane signaling receptor activity
AHML_14150	COG0392	lysyltransferase activity
AHML_14150	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
AHML_14160	COG2194	sulfuric ester hydrolase activity
AHML_14175	COG0670	Belongs to the BI1 family
AHML_14180	COG1289	transmembrane transporter activity
AHML_14185	COG2920	part of a sulfur-relay system
AHML_14190	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
AHML_14195	COG0285	dihydrofolate synthase activity
AHML_14200	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
AHML_14205	COG0101	tRNA pseudouridine synthase activity
AHML_14215	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
AHML_14220	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AHML_14225	COG0671	phosphoesterase, PA-phosphatase related
AHML_14230	COG1464	Belongs to the NlpA lipoprotein family
AHML_14245	COG3038	cytochrome b561
AHML_14280	COG0574	Belongs to the PEP-utilizing enzyme family
AHML_14280	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
AHML_14285	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
AHML_14350	COG1242	4 iron, 4 sulfur cluster binding
AHML_14355	COG0069	glutamate synthase activity
AHML_14355	COG0067	glutamate synthase
AHML_14355	COG0070	glutamate synthase
AHML_14360	COG0493	'glutamate synthase
AHML_14370	COG0765	amino acid transport
AHML_14375	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AHML_14390	COG0789	Transcriptional regulator
AHML_14405	COG4104	PAAR repeat-containing protein
AHML_14415	COG0513	Belongs to the DEAD box helicase family
AHML_14420	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AHML_14450	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AHML_14455	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
AHML_14460	COG0505	Belongs to the CarA family
AHML_14465	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
AHML_14475	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
AHML_14480	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
AHML_14485	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
AHML_14490	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AHML_14495	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
AHML_14500	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
AHML_14510	COG4138	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system
AHML_14520	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AHML_14520	COG2205	protein histidine kinase activity
AHML_14535	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
AHML_14560	COG0023	Translation Initiation Factor
AHML_14565	COG2119	membrane
AHML_14595	COG2203	Gaf domain
AHML_14595	COG2199	diguanylate cyclase activity
AHML_14610	COG0215	cysteine-tRNA ligase activity
AHML_14615	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
AHML_14625	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AHML_14630	COG3301	Polysulphide reductase, NrfD
AHML_14635	COG0437	4 iron, 4 sulfur cluster binding
AHML_14640	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
AHML_14720	COG2963	transposase activity
AHML_14725	COG3039	Transposase
AHML_14730	COG3718	enzyme involved in inositol metabolism
AHML_14740	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AHML_14745	COG0673	inositol 2-dehydrogenase activity
AHML_14750	COG1172	Belongs to the binding-protein-dependent transport system permease family
AHML_14760	COG1879	ABC-type sugar transport system periplasmic component
AHML_14765	COG0673	inositol 2-dehydrogenase activity
AHML_14780	COG3962	Belongs to the TPP enzyme family
AHML_14800	COG4372	Transposase
AHML_14825	COG0582	viral genome integration into host DNA
AHML_14835	COG0322	excinuclease ABC activity
AHML_14840	COG2197	response regulator
AHML_14845	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
AHML_14850	COG2835	tetraacyldisaccharide 4'-kinase activity
AHML_14855	COG1663	tetraacyldisaccharide 4'-kinase activity
AHML_14865	COG0658	competence protein
AHML_14865	COG2333	competence protein COMEC
AHML_14900	COG2916	Histone family protein nucleoid-structuring protein H-NS
AHML_14935	COG1522	sequence-specific DNA binding
AHML_14945	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AHML_15010	COG0433	COG0433 Predicted ATPase
AHML_15015	COG1448	Aminotransferase
AHML_15030	COG1199	ATP-dependent helicase activity
AHML_15040	COG0123	including yeast histone deacetylase and acetoin utilization protein
AHML_15045	COG0477	Major facilitator Superfamily
AHML_15050	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
AHML_15080	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
AHML_15095	COG2271	Major facilitator Superfamily
AHML_15100	COG3706	GGDEF domain
AHML_15105	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AHML_15110	COG0765	amino acid transport
AHML_15115	COG1126	abc transporter atp-binding protein
AHML_15130	COG0531	amino acid
AHML_15145	COG1253	flavin adenine dinucleotide binding
AHML_15150	COG0704	Plays a role in the regulation of phosphate uptake
AHML_15160	COG0581	inorganic phosphate transmembrane transporter activity
AHML_15165	COG0573	inorganic phosphate transmembrane transporter activity
AHML_15170	COG0590	tRNA wobble adenosine to inosine editing
AHML_15175	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
AHML_15195	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
AHML_15200	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
AHML_15205	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
AHML_15210	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
AHML_15215	COG2204	response regulator
AHML_15220	COG3852	Histidine kinase
AHML_15225	COG2204	response regulator
AHML_15235	COG2716	regulation of RNA biosynthetic process
AHML_15240	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
AHML_15245	COG0248	Ppx GppA phosphatase
AHML_15250	COG2239	Acts as a magnesium transporter
AHML_15260	COG1256	bacterial-type flagellum assembly
AHML_15265	COG1705	Flagellar rod assembly protein muramidase FlgJ
AHML_15265	COG3951	Flagellar rod assembly protein muramidase FlgJ
AHML_15270	COG1706	bacterial-type flagellum-dependent cell motility
AHML_15275	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
AHML_15280	COG4786	Flagellar basal body rod
AHML_15285	COG4787	bacterial-type flagellum-dependent cell motility
AHML_15300	COG1558	bacterial-type flagellum-dependent cell motility
AHML_15305	COG1815	bacterial-type flagellum-dependent cell motility
AHML_15310	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
AHML_15315	COG0784	Response regulator, receiver
AHML_15315	COG0835	chemotaxis
AHML_15320	COG1261	Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly
AHML_15335	COG0622	Phosphoesterase
AHML_15350	COG1187	pseudouridine synthase activity
AHML_15365	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
AHML_15370	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
AHML_15380	COG1349	DNA-binding transcription factor activity
AHML_15385	COG0697	spore germination
AHML_15415	COG1278	Cold shock
AHML_15455	COG3132	Protein of unknown function, DUF480
AHML_15465	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AHML_15495	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
AHML_15505	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
AHML_15510	COG1091	dTDP-4-dehydrorhamnose reductase activity
AHML_15515	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
AHML_15530	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
AHML_15530	COG0662	Cupin 2, conserved barrel domain protein
AHML_15540	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AHML_15545	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
AHML_15550	COG0297	glycogen (starch) synthase activity
AHML_15565	COG0110	maltose O-acetyltransferase activity
AHML_15570	COG2244	polysaccharide biosynthetic process
AHML_15590	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
AHML_15600	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AHML_15605	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AHML_15610	COG1309	transcriptional regulator
AHML_15625	COG1946	Acyl-CoA thioesterase
AHML_15635	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
AHML_15645	COG0009	L-threonylcarbamoyladenylate synthase
AHML_15655	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
AHML_15660	COG0512	Glutamine amidotransferase of anthranilate synthase
AHML_15660	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
AHML_15665	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
AHML_15670	COG0135	phosphoribosylanthranilate isomerase activity
AHML_15670	COG0134	indole-3-glycerol-phosphate synthase activity
AHML_15675	COG0133	tryptophan synthase activity
AHML_15680	COG0159	tryptophan synthase activity
AHML_15715	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
AHML_15735	COG3311	Transcriptional regulator
AHML_15750	COG1335	isochorismatase
AHML_15755	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
AHML_15760	COG1304	FMN binding
AHML_15765	COG0549	Belongs to the carbamate kinase family
AHML_15780	COG0583	DNA-binding transcription factor activity
AHML_15820	COG2003	Belongs to the UPF0758 family
AHML_15855	COG3381	protein complex oligomerization
AHML_15865	COG3005	denitrification pathway
AHML_15870	COG0745	RESPONSE REGULATOR receiver
AHML_15880	COG1879	ABC-type sugar transport system periplasmic component
AHML_15885	COG2205	protein histidine kinase activity
AHML_15885	COG0784	Response regulator, receiver
AHML_15885	COG2198	Histidine kinase
AHML_15890	COG2814	Major facilitator Superfamily
AHML_15895	COG0109	protoheme IX farnesyltransferase activity
AHML_15900	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
AHML_15905	COG1845	cytochrome c oxidase, subunit III
AHML_15910	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
AHML_15915	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
AHML_15960	COG2211	Major facilitator Superfamily
AHML_15975	COG0708	Exodeoxyribonuclease III
AHML_15995	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AHML_16000	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AHML_16020	COG0095	Lipoate-protein ligase
AHML_16050	COG0640	Transcriptional regulator
AHML_16065	COG1285	pathogenesis
AHML_16095	COG0484	heat shock protein binding
AHML_16100	COG0443	Heat shock 70 kDa protein
AHML_16105	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
AHML_16110	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
AHML_16115	COG0497	DNA recombination
AHML_16125	COG1227	inorganic diphosphatase activity
AHML_16135	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AHML_16140	COG0577	efflux transmembrane transporter activity
AHML_16140	COG1136	(ABC) transporter
AHML_16145	COG1538	Outer membrane efflux protein
AHML_16150	COG2375	cellular response to nickel ion
AHML_16155	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
AHML_16175	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AHML_16180	COG1396	sequence-specific DNA binding
AHML_16180	COG1917	Cupin 2, conserved barrel domain protein
AHML_16195	COG0531	amino acid
AHML_16205	COG0531	amino acid
AHML_16215	COG1283	sodium-dependent phosphate transmembrane transporter activity
AHML_16225	COG3384	dioxygenase
AHML_16230	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AHML_16230	COG2205	protein histidine kinase activity
AHML_16245	COG0813	purine-nucleoside phosphorylase activity
AHML_16260	COG0488	(ABC) transporter
AHML_16275	COG4319	ketosteroid isomerase
AHML_16280	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
AHML_16285	COG0083	homoserine kinase activity
AHML_16295	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
AHML_16300	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
AHML_16315	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
AHML_16325	COG0745	RESPONSE REGULATOR receiver
AHML_16330	COG4988	ABC transporter
AHML_16335	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
AHML_16355	COG1720	tRNA m6t6A37 methyltransferase activity
AHML_16370	COG0542	response to heat
AHML_16375	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
AHML_16380	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
AHML_16390	COG2190	(PTS) system
AHML_16405	COG3038	cytochrome b561
AHML_16420	COG0419	ATPase involved in DNA repair
AHML_16425	COG0420	3'-5' exonuclease activity
AHML_16435	COG2974	May be involved in recombination
AHML_16445	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
AHML_16445	COG4651	solute:proton antiporter activity
AHML_16460	COG0469	pyruvate kinase activity
AHML_16465	COG1196	nuclear chromosome segregation
AHML_16465	COG3264	Mechanosensitive ion channel
AHML_16475	COG2706	6-phosphogluconolactonase activity
AHML_16495	COG0281	malic enzyme
AHML_16510	COG0437	4 iron, 4 sulfur cluster binding
AHML_16515	COG3383	formate dehydrogenase (NAD+) activity
AHML_16515	COG3383	formate dehydrogenase (NAD+) activity
AHML_16550	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
AHML_16555	COG1910	domain protein
AHML_16560	COG3852	Histidine kinase
AHML_16565	COG2204	response regulator
AHML_16575	COG4662	Binding-protein-dependent transport system inner membrane component
AHML_16585	COG0746	molybdenum cofactor guanylyltransferase activity
AHML_16590	COG0303	'Molybdopterin
AHML_16595	COG1289	transmembrane transporter activity
AHML_16600	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
AHML_16630	COG3220	belongs to the UPF0276 family
AHML_16655	COG4166	transmembrane transport
AHML_16660	COG0601	transmembrane transport
AHML_16665	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AHML_16670	COG0444	Belongs to the ABC transporter superfamily
AHML_16675	COG4608	Belongs to the ABC transporter superfamily
AHML_16685	COG2971	BadF BadG BcrA BcrD
AHML_16695	COG0840	transmembrane signaling receptor activity
AHML_16710	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
AHML_16715	COG3724	N-succinylarginine dihydrolase activity
AHML_16720	COG0616	signal peptide processing
AHML_16725	COG1028	Short-chain dehydrogenase reductase Sdr
AHML_16730	COG0583	DNA-binding transcription factor activity
AHML_16740	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
AHML_16750	COG0583	DNA-binding transcription factor activity
AHML_16760	COG1881	PFAM PEBP family protein
AHML_16770	COG3408	Glycogen debranching enzyme
AHML_16770	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
AHML_16775	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
AHML_16780	COG0739	heme binding
AHML_16785	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
AHML_16805	COG2200	EAL domain
AHML_16810	COG3710	Transcriptional regulator
AHML_16815	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
AHML_16825	COG3091	SprT-like family
AHML_16835	COG1385	rRNA (uridine-N3-)-methyltransferase activity
AHML_16840	COG0189	ligase activity
AHML_16850	COG1678	Uncharacterized ACR, COG1678
AHML_16855	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
AHML_16860	COG3104	oligopeptide transport
AHML_16870	COG0714	Associated with various cellular activities
AHML_16885	COG1115	amino acid carrier protein
AHML_16890	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
AHML_16905	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
AHML_16915	COG1301	dicarboxylic acid transport
AHML_16920	COG2877	3-deoxy-8-phosphooctulonate synthase activity
AHML_16925	COG2912	Transglutaminase-like superfamily
AHML_16935	COG2890	protein-(glutamine-N5) methyltransferase activity
AHML_16940	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
AHML_16945	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
AHML_16950	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
AHML_16955	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
AHML_16960	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
AHML_16965	COG0737	Belongs to the 5'-nucleotidase family
AHML_16970	COG0193	aminoacyl-tRNA hydrolase activity
AHML_16975	COG0012	GTP binding
AHML_16980	COG0471	metal ion transport
AHML_16980	COG0490	domain, Protein
AHML_16990	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
AHML_17010	COG0366	Alpha amylase catalytic
AHML_17020	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
AHML_17020	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AHML_17020	COG1013	pyruvate-flavodoxin oxidoreductase activity
AHML_17020	COG0674	pyruvate-flavodoxin oxidoreductase activity
AHML_17030	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AHML_17040	COG1012	belongs to the aldehyde dehydrogenase family
AHML_17050	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
AHML_17065	COG0180	Tryptophanyl-tRNA synthetase
AHML_17075	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
AHML_17080	COG0338	D12 class N6 adenine-specific DNA methyltransferase
AHML_17090	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
AHML_17095	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
AHML_17125	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
AHML_17130	COG0583	DNA-binding transcription factor activity
AHML_17150	COG0583	DNA-binding transcription factor activity
AHML_17165	COG0739	heme binding
AHML_17175	COG3264	Mechanosensitive ion channel
AHML_17175	COG1511	domain protein
AHML_17180	COG0584	glycerophosphoryl diester phosphodiesterase
AHML_17190	COG1053	succinate dehydrogenase
AHML_17195	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
AHML_17200	COG3029	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
AHML_17225	COG3214	Protein conserved in bacteria
AHML_17260	COG0745	RESPONSE REGULATOR receiver
AHML_17265	COG0642	Histidine kinase
AHML_17275	COG0516	GMP reductase activity
AHML_17285	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
AHML_17290	COG3647	Membrane
AHML_17300	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AHML_17310	COG3706	GGDEF domain
AHML_17320	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AHML_17335	COG3706	GGDEF domain
AHML_17345	COG1335	isochorismatase
AHML_17350	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AHML_17355	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
AHML_17360	COG1702	phosphate starvation-inducible protein PhoH
AHML_17365	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
AHML_17370	COG4535	Mg2 and Co2 transporter CorC
AHML_17375	COG0815	Transfers the fatty acyl group on membrane lipoproteins
AHML_17380	COG2888	peptidyl-tyrosine sulfation
AHML_17385	COG0495	leucyl-tRNA aminoacylation
AHML_17400	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
AHML_17405	COG0799	negative regulation of ribosome biogenesis
AHML_17410	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
AHML_17415	COG0768	penicillin binding
AHML_17420	COG0772	Belongs to the SEDS family
AHML_17425	COG0772	Belongs to the SEDS family
AHML_17430	COG2951	lytic endotransglycosylase activity
AHML_17435	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
AHML_17440	COG1686	Belongs to the peptidase S11 family
AHML_17445	COG2921	Belongs to the UPF0250 family
AHML_17450	COG0321	lipoyl(octanoyl) transferase activity
AHML_17455	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
AHML_17465	COG3545	Serine hydrolase
AHML_17470	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
AHML_17490	COG0789	Transcriptional regulator
AHML_17500	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
AHML_17505	COG1970	mechanosensitive ion channel activity
AHML_17510	COG4974	Belongs to the 'phage' integrase family
AHML_17515	COG0716	FMN binding
AHML_17520	COG0312	modulator of DNA gyrase
AHML_17525	COG0312	modulator of DNA gyrase
AHML_17590	COG3275	phosphorelay sensor kinase activity
AHML_17595	COG3279	Response regulator of the LytR AlgR family
AHML_17600	COG1966	Carbon starvation protein
AHML_17610	COG0114	fumarate hydratase activity
AHML_17620	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
AHML_17640	COG1185	polyribonucleotide nucleotidyltransferase activity
AHML_17645	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
AHML_17650	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
AHML_17655	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
AHML_17660	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
AHML_17665	COG0195	Participates in both transcription termination and antitermination
AHML_17670	COG0779	Required for maturation of 30S ribosomal subunits
AHML_17675	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
AHML_17680	COG0149	triose-phosphate isomerase activity
AHML_17685	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AHML_17690	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
AHML_17695	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AHML_17700	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
AHML_17705	COG1534	Rna-binding protein
AHML_17715	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
AHML_17720	COG1360	Flagellar Motor Protein
AHML_17725	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
AHML_17730	COG1722	exodeoxyribonuclease VII activity
AHML_17735	COG0142	geranyltranstransferase activity
AHML_17740	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
AHML_17765	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
AHML_17770	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
AHML_17775	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
AHML_17780	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
AHML_17805	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AHML_17805	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AHML_17810	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
AHML_17825	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
AHML_17840	COG3381	protein complex oligomerization
AHML_17860	COG3300	MHYT domain
AHML_17860	COG5001	Diguanylate cyclase
AHML_17870	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AHML_17875	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AHML_17880	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
AHML_17885	COG0511	ligase activity, forming carbon-carbon bonds
AHML_17890	COG0439	Biotin carboxylase
AHML_17900	COG4145	pantothenate transmembrane transporter activity
AHML_17905	COG1263	PTS System
AHML_17905	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AHML_17905	COG2190	(PTS) system
AHML_17910	COG0583	DNA-binding transcription factor activity
AHML_17915	COG0604	alcohol dehydrogenase
AHML_17920	COG2264	protein methyltransferase activity
AHML_17935	COG0778	Nitroreductase
AHML_17940	COG0446	pyridine nucleotide-disulphide oxidoreductase
AHML_17940	COG1902	pentaerythritol trinitrate reductase activity
AHML_17945	COG0616	signal peptide processing
AHML_17965	COG3139	Protein of unknown function (DUF1315)
AHML_17970	COG0252	asparaginase activity
AHML_17975	COG0786	glutamate:sodium symporter activity
AHML_17985	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
AHML_17990	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
AHML_17995	COG0384	phenazine biosynthesis protein PhzF
AHML_18000	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
AHML_18005	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AHML_18010	COG0175	sulfate reduction
AHML_18015	COG2113	Glycine betaine
AHML_18020	COG4176	ABC-type proline glycine betaine transport system permease component
AHML_18025	COG4175	Glycine betaine
AHML_18035	COG3610	response to peptide
AHML_18040	COG2966	Psort location CytoplasmicMembrane, score
AHML_18050	COG0521	Mo-molybdopterin cofactor biosynthetic process
AHML_18065	COG1028	Short-chain dehydrogenase reductase Sdr
AHML_18075	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AHML_18100	COG2986	histidine ammonia-lyase
AHML_18125	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AHML_18130	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AHML_18165	COG1858	cytochrome C peroxidase
AHML_18175	COG2313	pseudouridylate synthase activity
AHML_18180	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AHML_18185	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AHML_18185	COG2146	nitrite reductase [NAD(P)H] activity
AHML_18190	COG2146	nitrite reductase [NAD(P)H] activity
AHML_18190	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AHML_18195	COG1116	anion transmembrane transporter activity
AHML_18200	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AHML_18205	COG1116	anion transmembrane transporter activity
AHML_18205	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AHML_18220	COG0243	molybdopterin cofactor binding
AHML_18245	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
AHML_18265	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
AHML_18270	COG2195	Cleaves the N-terminal amino acid of tripeptides
AHML_18280	COG4608	Belongs to the ABC transporter superfamily
AHML_18285	COG0444	Belongs to the ABC transporter superfamily
AHML_18295	COG4239	(ABC) transporter, permease
AHML_18300	COG4174	ABC transporter (Permease)
AHML_18315	COG0811	peptide transport
AHML_18320	COG0811	peptide transport
AHML_18325	COG0848	biopolymer transport protein
AHML_18350	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AHML_18355	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AHML_18360	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AHML_18365	COG0840	transmembrane signaling receptor activity
AHML_18375	COG1278	Cold shock
AHML_18385	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
AHML_18390	COG1162	GTPase activity
AHML_18395	COG0688	phosphatidylethanolamine metabolic process
AHML_18400	COG4628	conserved protein (DUF2132)
AHML_18420	COG3300	MHYT domain
AHML_18420	COG5001	Diguanylate cyclase
AHML_18425	COG3076	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome
AHML_18430	COG4412	M6 family metalloprotease domain protein
AHML_18430	COG3291	Pkd domain containing protein
AHML_18445	COG1132	(ABC) transporter
AHML_18455	COG1404	Belongs to the peptidase S8 family
AHML_18460	COG2897	thiosulfate sulfurtransferase activity
AHML_18465	COG2066	Belongs to the glutaminase family
AHML_18470	COG3171	Protein conserved in bacteria
AHML_18475	COG0220	tRNA (guanine-N7-)-methyltransferase activity
AHML_18480	COG2234	aminopeptidase activity
AHML_18480	COG4935	Belongs to the peptidase S8 family
AHML_18485	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AHML_18490	COG2200	EAL domain
AHML_18495	COG1090	epimerase
AHML_18500	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
AHML_18505	COG4181	ATPase activity
AHML_18510	COG2755	lipolytic protein G-D-S-L family
AHML_18515	COG0784	Response regulator, receiver
AHML_18515	COG0835	chemotaxis
AHML_18525	COG0569	domain protein
AHML_18525	COG2985	domain, Protein
AHML_18530	COG1272	protein, Hemolysin III
AHML_18535	COG0076	glutamate decarboxylase activity
AHML_18540	COG2917	probably involved in intracellular septation
AHML_18545	COG2350	Protein conserved in bacteria
AHML_18555	COG1555	photosystem II stabilization
AHML_18560	COG1210	Utp--glucose-1-phosphate uridylyltransferase
AHML_18565	COG3104	oligopeptide transport
AHML_18570	COG0745	RESPONSE REGULATOR receiver
AHML_18600	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AHML_18615	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
AHML_18620	COG1280	lysine exporter protein (LysE YggA)
AHML_18625	COG0316	Belongs to the HesB IscA family
AHML_18635	COG0038	chloride channel
AHML_18640	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
AHML_18655	COG0671	phosphoesterase, PA-phosphatase related
AHML_18665	COG0784	Response regulator, receiver
AHML_18665	COG3437	response regulator, receiver
AHML_18675	COG2076	Multidrug Resistance protein
AHML_18685	COG0346	lactoylglutathione lyase activity
AHML_18690	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AHML_18695	COG1643	Atp-dependent helicase
AHML_18705	COG1489	DNA binding
AHML_18710	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
AHML_18715	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AHML_18730	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
AHML_18735	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
AHML_18755	COG1924	4 iron, 4 sulfur cluster binding
AHML_18760	COG1775	2-hydroxyglutaryl-CoA dehydratase, D-component
AHML_18765	COG0842	Transport permease protein
AHML_18770	COG1131	(ABC) transporter
AHML_18785	COG0163	prenyltransferase activity
AHML_18790	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
AHML_18795	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
AHML_18810	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
AHML_18845	COG0840	transmembrane signaling receptor activity
AHML_18865	COG0529	Catalyzes the synthesis of activated sulfate
AHML_18870	COG0471	metal ion transport
AHML_18870	COG3273	potassium ion transport
AHML_18875	COG2895	sulfate adenylyltransferase (ATP) activity
AHML_18880	COG0175	sulfate reduction
AHML_18885	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
AHML_18885	COG1648	precorrin-2 dehydrogenase activity
AHML_18890	COG0330	HflC and HflK could
AHML_18895	COG1585	Membrane protein implicated in regulation of membrane protease activity
AHML_18900	COG0517	IMP dehydrogenase activity
AHML_18900	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
AHML_18905	COG0488	(ABC) transporter
AHML_18915	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
AHML_18920	COG0583	DNA-binding transcription factor activity
AHML_18955	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AHML_18965	COG0668	transmembrane transport
AHML_18975	COG2731	YhcH YjgK YiaL family protein
AHML_18990	COG1794	racemase activity, acting on amino acids and derivatives
AHML_19005	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AHML_19030	COG0733	neurotransmitter:sodium symporter activity
AHML_19040	COG0733	neurotransmitter:sodium symporter activity
AHML_19055	COG0561	phosphatase activity
AHML_19070	COG1522	sequence-specific DNA binding
AHML_19085	COG1846	Transcriptional regulator
AHML_19090	COG1764	response to oxidative stress
AHML_19095	COG2130	NADP-dependent
AHML_19100	COG1051	belongs to the nudix hydrolase family
AHML_19120	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
AHML_19125	COG1640	4-alpha-glucanotransferase
AHML_19130	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
AHML_19135	COG0676	glucose-6-phosphate 1-epimerase activity
AHML_19140	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
AHML_19145	COG0840	transmembrane signaling receptor activity
AHML_19150	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
AHML_19155	COG2885	chlorophyll binding
AHML_19160	COG0823	Involved in the tonB-independent uptake of proteins
AHML_19175	COG0811	peptide transport
AHML_19180	COG0824	Thioesterase
AHML_19185	COG3790	cyd operon protein YbgE
AHML_19190	COG4890	Cyd operon protein YbgT
AHML_19195	COG1294	oxidase, subunit
AHML_19200	COG1271	oxidase subunit
AHML_19205	COG2255	four-way junction helicase activity
AHML_19210	COG0632	four-way junction helicase activity
AHML_19215	COG0840	transmembrane signaling receptor activity
AHML_19220	COG0442	prolyl-tRNA aminoacylation
AHML_19225	COG4221	oxidoreductase activity
AHML_19240	COG1024	Enoyl-CoA hydratase
AHML_19250	COG0110	maltose O-acetyltransferase activity
AHML_19260	COG4166	transmembrane transport
AHML_19275	COG1872	DUF167
AHML_19280	COG0762	integral membrane protein
AHML_19285	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
AHML_19290	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
AHML_19305	COG3022	response to hydroperoxide
AHML_19310	COG0513	Belongs to the DEAD box helicase family
AHML_19315	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
AHML_19340	COG0735	belongs to the Fur family
AHML_19345	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
AHML_19360	COG0776	regulation of translation
AHML_19390	COG0560	Phosphoserine phosphatase
AHML_19400	COG5001	Diguanylate cyclase
AHML_19400	COG5002	protein histidine kinase activity
AHML_19400	COG3447	MASE1 domain protein
AHML_19405	COG0813	purine-nucleoside phosphorylase activity
AHML_19410	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
AHML_19415	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
AHML_19420	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
AHML_19430	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
AHML_19435	COG0084	hydrolase, TatD family'
AHML_19450	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
AHML_19455	COG0004	ammonium transporteR
AHML_19460	COG4974	Belongs to the 'phage' integrase family
AHML_19555	COG4695	Portal protein
AHML_19680	COG0795	lipopolysaccharide-transporting ATPase activity
AHML_19685	COG0795	lipopolysaccharide-transporting ATPase activity
AHML_19690	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
AHML_19695	COG2927	DNA polymerase III (CHI subunit)
AHML_19700	COG0525	valine-tRNA ligase activity
AHML_19705	COG1253	flavin adenine dinucleotide binding
AHML_19710	COG0586	Pfam SNARE associated Golgi protein
AHML_19715	COG1686	Belongs to the peptidase S11 family
AHML_19720	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
AHML_19725	COG0527	aspartate kinase activity
AHML_19730	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
AHML_19740	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
AHML_19745	COG1546	Belongs to the CinA family
AHML_19765	COG0582	viral genome integration into host DNA
AHML_19770	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
AHML_19790	COG3068	Protein conserved in bacteria
AHML_19800	COG0739	heme binding
AHML_19820	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
AHML_19825	COG1121	(ABC) transporter
AHML_19830	COG1108	ABC-type Mn2 Zn2 transport systems permease components
AHML_19845	COG0697	spore germination
AHML_19850	COG1573	uracil-dna glycosylase
AHML_19855	COG2962	Rard protein
AHML_19865	COG2827	Endonuclease containing a URI domain
AHML_19880	COG1842	Phage shock protein A
AHML_19885	COG0204	Acyl-transferase
AHML_19910	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AHML_19955	COG0187	DNA topoisomerase II activity
AHML_19960	COG1289	transmembrane transporter activity
AHML_19965	COG1566	PFAM secretion protein HlyD family protein
AHML_19980	COG1051	belongs to the nudix hydrolase family
AHML_19985	COG3150	esterase
AHML_19995	COG3151	Protein conserved in bacteria
AHML_20000	COG0494	nUDIX hydrolase
AHML_20005	COG1538	Outer membrane efflux protein
AHML_20010	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
AHML_20010	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
AHML_20015	COG1560	Kdo2-lipid A biosynthetic process
AHML_20035	COG1392	Phosphate transport regulator
AHML_20040	COG0306	phosphate transporter
AHML_20045	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
AHML_20070	COG0583	DNA-binding transcription factor activity
AHML_20075	COG1380	Effector of murein hydrolase LrgA
AHML_20080	COG1346	cytolysis
AHML_20095	COG0617	tRNA 3'-terminal CCA addition
AHML_20105	COG3267	Type II secretory pathway component ExeA
AHML_20105	COG3409	Peptidoglycan-binding domain 1 protein
AHML_20115	COG1194	a g-specific adenine glycosylase
AHML_20120	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
AHML_20130	COG3111	PFAM Bacterial OB fold (BOF) protein
AHML_20135	COG3240	lipase activity
AHML_20150	COG3009	Protein conserved in bacteria
AHML_20155	COG3008	intermembrane lipid transfer
AHML_20155	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
AHML_20160	COG2995	paraquat-inducible protein a
AHML_20170	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AHML_20180	COG2203	Gaf domain
AHML_20180	COG5001	Diguanylate cyclase
AHML_20180	COG3706	GGDEF domain
AHML_20180	COG4251	negative regulation of phosphorylation
AHML_20185	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AHML_20190	COG2813	Specifically methylates the guanine in position
AHML_20195	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
AHML_20200	COG0297	glycogen (starch) synthase activity
AHML_20215	COG1757	Na H antiporter
AHML_20220	COG0583	DNA-binding transcription factor activity
AHML_20225	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
AHML_20230	COG3842	ATPase activity
AHML_20240	COG1177	transmembrane transport
AHML_20245	COG1012	belongs to the aldehyde dehydrogenase family
AHML_20255	COG5006	permease, DMT superfamily
AHML_20260	COG1522	sequence-specific DNA binding
AHML_20265	COG0110	maltose O-acetyltransferase activity
AHML_20270	COG0366	Alpha amylase catalytic
AHML_20275	COG1263	PTS System
AHML_20275	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AHML_20295	COG0252	asparaginase activity
AHML_20310	COG1803	Methylglyoxal synthase
AHML_20335	COG1444	tRNA N-acetyltransferase activity
AHML_20340	COG1028	Short-chain dehydrogenase reductase Sdr
AHML_20345	COG0835	chemotaxis
AHML_20345	COG0784	Response regulator, receiver
AHML_20370	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
AHML_20375	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
AHML_20390	COG0477	Major facilitator Superfamily
AHML_20395	COG0523	cobalamin synthesis protein
AHML_20410	COG1280	lysine exporter protein (LysE YggA)
AHML_20430	COG1049	propionate catabolic process, 2-methylcitrate cycle
AHML_20435	COG1752	Esterase of the alpha-beta hydrolase superfamily
AHML_20440	COG0840	transmembrane signaling receptor activity
AHML_20445	COG0840	transmembrane signaling receptor activity
AHML_20455	COG5002	protein histidine kinase activity
AHML_20455	COG5001	Diguanylate cyclase
AHML_20455	COG3447	MASE1 domain protein
AHML_20460	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AHML_20465	COG0508	dehydrogenase complex catalyzes the overall conversion of
AHML_20470	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
AHML_20475	COG2186	Transcriptional regulator
AHML_20505	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
AHML_20510	COG1459	type II secretion system
AHML_20525	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
AHML_20530	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
AHML_20535	COG0494	nUDIX hydrolase
AHML_20545	COG0653	protein targeting
AHML_20555	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
AHML_20560	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
AHML_20565	COG0849	cell division
AHML_20570	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
AHML_20575	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
AHML_20580	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
AHML_20585	COG0772	Belongs to the SEDS family
AHML_20590	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
AHML_20595	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
AHML_20600	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
AHML_20610	COG0768	penicillin binding
AHML_20615	COG3116	cell division
AHML_20620	COG0275	rRNA processing
AHML_20625	COG2001	Belongs to the MraZ family
AHML_20630	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
AHML_20635	COG3107	peptidoglycan biosynthetic process
AHML_20640	COG0792	nuclease activity
AHML_20645	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
AHML_20650	COG2823	Periplasmic or secreted lipoprotein
AHML_20655	COG2969	positive regulation of protein catabolic process
AHML_20660	COG0625	glutathione transferase activity
AHML_20665	COG2857	Cytochrome c1
AHML_20670	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
AHML_20675	COG0723	plastoquinol--plastocyanin reductase activity
AHML_20685	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
AHML_20690	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
AHML_20695	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
AHML_20705	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AHML_20710	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AHML_20740	COG3964	amidohydrolase
AHML_20755	COG3711	transcriptional antiterminator
AHML_20755	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
AHML_20760	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
AHML_20765	COG1660	Displays ATPase and GTPase activities
AHML_20770	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
AHML_20780	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
AHML_20785	COG1137	ATPase activity
AHML_20790	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
AHML_20795	COG3117	lipopolysaccharide transmembrane transporter activity
AHML_20800	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
AHML_20805	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
AHML_20805	COG0517	IMP dehydrogenase activity
AHML_20810	COG1127	ABC transporter
AHML_20815	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
AHML_20820	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
AHML_20825	COG2854	intermembrane phospholipid transfer
AHML_20835	COG5007	Belongs to the BolA IbaG family
AHML_20840	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
AHML_20845	COG0312	modulator of DNA gyrase
AHML_20850	COG3028	Belongs to the UPF0307 family
AHML_20860	COG2926	Belongs to the UPF0265 family
AHML_20870	COG1396	sequence-specific DNA binding
AHML_20875	COG3135	benzoate transporter
AHML_20900	COG0840	transmembrane signaling receptor activity
AHML_20905	COG3047	cAMP biosynthetic process
AHML_20920	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
AHML_20925	COG2197	response regulator
AHML_20930	COG0629	single-stranded DNA binding
AHML_20955	COG1278	Cold shock
AHML_20960	COG4771	TonB-dependent receptor
AHML_20965	COG2203	Gaf domain
AHML_20965	COG4251	negative regulation of phosphorylation
AHML_20965	COG5001	Diguanylate cyclase
AHML_20965	COG3706	GGDEF domain
AHML_20970	COG2205	protein histidine kinase activity
AHML_20975	COG0745	RESPONSE REGULATOR receiver
AHML_21005	COG0346	lactoylglutathione lyase activity
AHML_21015	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
AHML_21020	COG1074	ATP-dependent DNA helicase activity
AHML_21025	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
AHML_21030	COG2259	Doxx family
AHML_21035	COG1741	Belongs to the pirin family
AHML_21045	COG0583	DNA-binding transcription factor activity
AHML_21070	COG1175	transmembrane transport
AHML_21080	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
AHML_21090	COG3706	GGDEF domain
AHML_21110	COG1247	-acetyltransferase
AHML_21115	COG0753	catalase activity
AHML_21140	COG0494	nUDIX hydrolase
AHML_21145	COG0628	permease
AHML_21150	COG4221	oxidoreductase activity
AHML_21155	COG2957	Belongs to the agmatine deiminase family
AHML_21165	COG3284	Transcriptional regulator
AHML_21180	COG1461	Dihydroxyacetone kinase
AHML_21185	COG2376	Dihydroxyacetone kinase
AHML_21190	COG2252	PERMEase
AHML_21200	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
AHML_21205	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
AHML_21210	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
AHML_21215	COG0049	tRNA binding
AHML_21220	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
AHML_21225	COG2168	tRNA wobble position uridine thiolation
AHML_21230	COG2923	Belongs to the DsrF TusC family
AHML_21240	COG0251	oxidation-reduction process
AHML_21245	COG2964	Protein conserved in bacteria
AHML_21255	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
AHML_21260	COG0085	RNA polymerase activity
AHML_21265	COG0222	ribosome binding
AHML_21270	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
AHML_21275	COG0081	regulation of translation
AHML_21280	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
AHML_21285	COG0250	Participates in transcription elongation, termination and antitermination
AHML_21290	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
AHML_21295	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
AHML_21310	COG0812	UDP-N-acetylmuramate dehydrogenase activity
AHML_21315	COG0569	domain protein
AHML_21320	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
AHML_21340	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
AHML_21345	COG3005	denitrification pathway
AHML_21350	COG0243	molybdopterin cofactor binding
AHML_21360	COG2205	protein histidine kinase activity
AHML_21365	COG0745	RESPONSE REGULATOR receiver
AHML_21380	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
AHML_21395	COG2204	response regulator
AHML_21405	COG2205	protein histidine kinase activity
AHML_21425	COG5413	integral membrane protein
AHML_21435	COG1522	sequence-specific DNA binding
AHML_21440	COG2502	aspartate--ammonia ligase
AHML_21445	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
AHML_21450	COG0542	response to heat
AHML_21460	COG0564	pseudouridine synthase activity
AHML_21465	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AHML_21470	COG0446	pyridine nucleotide-disulphide oxidoreductase
AHML_21480	COG3681	Belongs to the UPF0597 family
AHML_21485	COG2964	Protein conserved in bacteria
AHML_21495	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
AHML_21500	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
AHML_21505	COG1979	alcohol dehydrogenase
AHML_21510	COG2207	Transcriptional regulator
AHML_21525	COG0688	phosphatidylethanolamine metabolic process
AHML_21535	COG0540	Belongs to the ATCase OTCase family
AHML_21540	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
AHML_21545	COG1438	arginine binding
AHML_21550	COG1288	antiporter activity
AHML_21555	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
AHML_21585	COG0840	transmembrane signaling receptor activity
AHML_21605	COG3250	beta-galactosidase activity
AHML_21610	COG1609	Transcriptional regulator
AHML_21615	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
AHML_21625	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
AHML_21630	COG2017	converts alpha-aldose to the beta-anomer
AHML_21635	COG0667	Aldo Keto reductase
AHML_21640	COG1968	undecaprenyl-diphosphatase activity
AHML_21645	COG3806	Anti-sigma factor
AHML_21650	COG1595	DNA-templated transcription, initiation
AHML_21670	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
AHML_21675	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
AHML_21690	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AHML_21700	COG2146	nitrite reductase [NAD(P)H] activity
AHML_21705	COG2116	formate transmembrane transporter activity
AHML_21710	COG1648	precorrin-2 dehydrogenase activity
AHML_21710	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
AHML_21715	COG2239	Acts as a magnesium transporter
AHML_21725	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
AHML_21730	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
AHML_21740	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
AHML_21750	COG0514	ATP-dependent DNA helicase (RecQ)
AHML_21755	COG2050	protein possibly involved in aromatic compounds catabolism
AHML_21765	COG2258	MOSC domain
AHML_21770	COG1177	transmembrane transport
AHML_21775	COG1176	ABC-type spermidine putrescine transport system, permease component I
AHML_21780	COG3842	ATPase activity
AHML_21800	COG0174	glutamine synthetase
AHML_21805	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
AHML_21820	COG3045	CreA protein
AHML_21825	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AHML_21830	COG0443	Heat shock 70 kDa protein
AHML_21845	COG0366	Alpha amylase catalytic
AHML_21860	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
AHML_21865	COG0745	RESPONSE REGULATOR receiver
AHML_21870	COG2205	protein histidine kinase activity
AHML_21880	COG0281	malic enzyme
AHML_21885	COG0702	epimerase
AHML_21890	COG0254	rRNA binding
AHML_21895	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
AHML_21915	COG0129	dihydroxy-acid dehydratase activity
AHML_21920	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
AHML_21925	COG3978	acetolactate synthase activity
AHML_21935	COG0606	chelatase, subunit chli
AHML_21940	COG0204	Acyl-transferase
AHML_21945	COG0204	Acyl-transferase
AHML_21950	COG1683	Conserved Protein
AHML_21960	COG1335	isochorismatase
AHML_21970	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
AHML_21975	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
AHML_21980	COG3639	organic phosphonate transmembrane transporter activity
AHML_21985	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
AHML_21990	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
AHML_22000	COG3084	Protein conserved in bacteria
AHML_22005	COG2203	Gaf domain
AHML_22005	COG3706	GGDEF domain
AHML_22005	COG4251	negative regulation of phosphorylation
AHML_22005	COG5001	Diguanylate cyclase
AHML_22010	COG0789	Transcriptional regulator
AHML_22020	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
AHML_22025	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
AHML_22030	COG1561	YicC-like family, N-terminal region
AHML_22050	COG3306	glycosyltransferase involved in LPS biosynthesis
AHML_22065	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AHML_22075	COG0156	8-amino-7-oxononanoate synthase activity
AHML_22080	COG1063	alcohol dehydrogenase
AHML_22085	COG3245	cytochrome
AHML_22095	COG0210	DNA helicase
AHML_22100	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
AHML_22105	COG2166	iron-sulfur cluster assembly
AHML_22110	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
AHML_22120	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
AHML_22125	COG0848	biopolymer transport protein
AHML_22130	COG0811	peptide transport
AHML_22135	COG0811	peptide transport
AHML_22145	COG2771	luxR family
AHML_22150	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
AHML_22155	COG1349	DNA-binding transcription factor activity
AHML_22160	COG0745	RESPONSE REGULATOR receiver
AHML_22165	COG2205	protein histidine kinase activity
AHML_22175	COG4452	Inner membrane protein CreD
AHML_22180	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
AHML_22185	COG0355	proton-transporting ATP synthase activity, rotational mechanism
AHML_22190	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
AHML_22195	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
AHML_22200	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
AHML_22205	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
AHML_22210	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
AHML_22220	COG0356	it plays a direct role in the translocation of protons across the membrane
AHML_22230	COG1475	DNA binding
AHML_22235	COG1192	Involved in chromosome partitioning
AHML_22240	COG0357	Ribosomal RNA small subunit methyltransferase G
AHML_22245	COG0445	tRNA wobble uridine modification
AHML_22250	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
AHML_22255	COG4774	siderophore transport
AHML_22260	COG4615	Cyclic peptide transporter
AHML_22265	COG1120	ATPase activity
AHML_22280	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
AHML_22285	COG0706	membrane insertase activity
AHML_22290	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
AHML_22295	COG0594	ribonuclease P activity
AHML_22300	COG0230	Belongs to the bacterial ribosomal protein bL34 family