locus-tag	class	description
U876_00005	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
U876_00010	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
U876_00015	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
U876_00020	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
U876_00030	ENOG4105D29	Helix-turn-helix type 11 domain protein
U876_00035	ENOG4108ZNX	Heat shock protein
U876_00040	ENOG4108ZNX	Heat shock protein
U876_00045	ENOG4105JKW	Valine--pyruvate aminotransferase
U876_00060	ENOG4105C2C	drug resistance transporter, Bcr CflA
U876_00065	ENOG4105EEX	Two component transcriptional regulator (Winged helix family
U876_00070	ENOG4105C08	Histidine kinase
U876_00085	ENOG4105C8X	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity)
U876_00090	ENOG4105D9K	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity)
U876_00095	ENOG4105DC8	reductase
U876_00100	ENOG4105BZU	Histidine kinase
U876_00105	ENOG4105BZS	acriflavin resistance protein
U876_00110	ENOG410624X	efflux transporter, rnd family, mfp subunit
U876_00115	ENOG4105Y7M	Transcriptional regulator, TetR family
U876_00145	ENOG4105CA9	Pyruvate kinase
U876_00150	ENOG4105CXY	transporter
U876_00155	ENOG4106JDA	Phosphoglycerate transport regulatory protein PGTC
U876_00165	ENOG4107TXD	phosphoglycerate transport system transcriptional regulatory protein pgta
U876_00175	ENOG4105DQF	Hydrolase
U876_00180	ENOG4108EUD	Lysophospholipase
U876_00195	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
U876_00200	ENOG4105VFG	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity)
U876_00210	ENOG4105DKP	glycosyl transferase, family 9
U876_00215	ENOG4108W7E	Catalyzes the ATP-dependent phosphorylation of the 3- deoxy-D-manno-octulosonic acid (Kdo) residue in Kdo-lipid IV(A) at the 4-OH position (By similarity)
U876_00225	ENOG4105EMK	carboxylate amino acid amine transporter
U876_00255	ENOG4108M6U	Universal stress protein A
U876_00260	ENOG4105RKW	reductase (By
U876_00265	ENOG4105BZU	Histidine kinase
U876_00270	ENOG41090A1	ferritin
U876_00275	ENOG4105CBX	hi0933 family
U876_00280	ENOG4105EU0	Major facilitator Superfamily
U876_00300	ENOG4108N3D	putative enzyme
U876_00305	ENOG4108NN8	Fimbrial protein
U876_00310	ENOG4108GWT	fimbrillin MatB
U876_00315	ENOG4107ZHV	Transcriptional regulator
U876_00320	ENOG4105BZU	Histidine kinase
U876_00330	ENOG4108HRK	Histidine kinase
U876_00335	ENOG4105DY9	regulatoR
U876_00340	ENOG4105FCD	Major Facilitator
U876_00345	ENOG4105CY8	phosphoribosylaminoimidazole carboxylase atpase subunit
U876_00350	ENOG4108UM6	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity)
U876_00365	ENOG41063Z6	transcriptional regulator, lysR family
U876_00370	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
U876_00375	ENOG4105F03	Provides the (R)-glutamate required for cell wall biosynthesis (By similarity)
U876_00410	ENOG4105CUZ	uba thif-type nad fad binding protein
U876_00415	ENOG4105P9C	Participates in cysteine desulfuration mediated by SufS. Cysteine desulfuration mobilizes sulfur from L-cysteine to yield L-alanine and constitutes an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules. Functions as a sulfur acceptor for SufS, by mediating the direct transfer of the sulfur atom from the S-sulfanylcysteine of SufS, an intermediate product of cysteine desulfuration process (By similarity)
U876_00420	ENOG4105C9B	Cysteine desulfurase
U876_00425	ENOG4105C4R	Atp-dependent dna helicase
U876_00430	ENOG4105BZU	Histidine kinase
U876_00435	ENOG4105MPD	Cytochrome
U876_00440	ENOG4105CPQ	Dehydrogenase
U876_00445	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
U876_00450	ENOG41062JF	Transcriptional regulator
U876_00455	ENOG4105CUI	Catalyzes the interconversion between ADP-D-glycero- beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose (By similarity)
U876_00470	ENOG4105W1T	Glycosyl Transferase
U876_00490	ENOG4105DSJ	YicC domain protein
U876_00495	ENOG4105ED0	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates (By similarity)
U876_00500	ENOG4107QP2	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
U876_00525	ENOG4105PC1	Conserved Protein
U876_00535	ENOG4105E27	serine threonine protein kinase
U876_00540	ENOG4108Z33	Thiol disulfide Interchange Protein
U876_00545	ENOG4105S7S	phosphonate abc transporter
U876_00550	ENOG4108VA1	ABC transporter
U876_00555	ENOG4105EHI	Phosphonate ABC transporter, periplasmic
U876_00560	ENOG4107RH7	Nicotinate phosphoribosyltransferase
U876_00565	ENOG4108RWI	nicotinamidase
U876_00575	ENOG4105EWC	Purine nucleoside phosphorylase
U876_00580	ENOG4106HNH	Acyl-transferase
U876_00585	ENOG4106HNH	Acyl-transferase
U876_00590	ENOG4105C0P	Mg chelatase subunit ChlI
U876_00600	ENOG4105P3Y	Acetolactate synthase 2 regulatory subunit
U876_00605	ENOG4105CM2	brancheD-chain amino acid aminotransferase
U876_00610	ENOG4105C01	Dihydroxy-acid dehydratase
U876_00615	ENOG4105C7B	Threonine dehydratase
U876_00620	ENOG4105UYK	outer membrane protein a
U876_00630	ENOG4105C25	Primosomal protein n'
U876_00635	ENOG4105VFB	Binds the 23S rRNA (By similarity)
U876_00640	ENOG4105CGD	Nad-dependent epimerase dehydratase
U876_00645	ENOG4105C6K	Malic enzyme
U876_00655	ENOG4105JJR	Histidine kinase
U876_00660	ENOG4107EXC	regulatoR
U876_00665	ENOG4107R9T	Catalyzes the formation of 5-methyl-uridine at position 54 (m5U54) in all tRNAs (By similarity)
U876_00680	ENOG4107R28	alpha amylase, catalytic region
U876_00695	ENOG4105R8A	Heat shock protein
U876_00700	ENOG4105C5I	Dehydrogenase
U876_00705	ENOG4108RH0	Crea protein
U876_00720	ENOG4108V7X	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
U876_00725	ENOG4105CFQ	glutamine synthetase
U876_00730	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
U876_00740	ENOG4108HM4	ABC transporter
U876_00745	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
U876_00750	ENOG4105F38	ABC transporter, permease
U876_00755	ENOG4105D38	putrescine abc transporter
U876_00760	ENOG4108RPX	mosc domain containing protein
U876_00775	ENOG4108VUY	thioesterase Superfamily protein
U876_00780	ENOG4105C9U	ATP-dependent DNA helicase RecQ
U876_00785	ENOG4105N7H	Cytochrome
U876_00790	ENOG4105CNG	UPF0061 protein
U876_00800	ENOG4105EX9	Membrane
U876_00805	ENOG4108YYX	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. Modulates RNA-binding and helicase activities of the degradosome (By similarity)
U876_00810	ENOG4108NVR	Methyl-accepting chemotaxis
U876_00815	ENOG4105CJW	magnesium transporter
U876_00820	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
U876_00825	ENOG4107V9H	nitrite transporter
U876_00830	ENOG4105WZK	nitrite reductase NADPH small subunit
U876_00840	ENOG4107QZF	nitrite reductase NADPH large subunit
U876_00855	ENOG4105C4N	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis (By similarity)
U876_00860	ENOG4108R5P	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery (By similarity)
U876_00870	ENOG4105C75	arginyL-tRNA synthetase
U876_00880	ENOG4105K6V	RNA polymerase
U876_00885	ENOG4108NIX	Factor ChrR
U876_00890	ENOG4105DWR	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity)
U876_00895	ENOG4105CPC	Aldo Keto reductase
U876_00900	ENOG4105ENN	converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose (By similarity)
U876_00905	ENOG4105CRD	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P) (By similarity)
U876_00910	ENOG4105F0Z	galactose-1-phosphate uridylyltransferase
U876_00915	ENOG4105CMR	udp-glucose 4-epimerase
U876_00920	ENOG41060NJ	transcriptional regulator
U876_00925	ENOG4105CNT	hydrolase family 2
U876_00935	ENOG4105C2J	ABC transporter
U876_00940	ENOG4107SDZ	Galactoside transport system permease protein mglC
U876_00945	ENOG4105C8Q	Methyl-accepting chemotaxis
U876_00970	ENOG4105C5B	carbamate kinase
U876_00975	ENOG4105DBV	ornithine carbamoyltransferase
U876_00980	ENOG4105CSX	c4-dicarboxylate anaerobic carrier
U876_00985	ENOG410682Y	Regulates arginine biosynthesis genes (By similarity)
U876_00990	ENOG4108R9M	Involved in allosteric regulation of aspartate carbamoyltransferase (By similarity)
U876_00995	ENOG4105CXT	aspartate transcarbamylase
U876_01010	ENOG4105DJ4	phosphatidylserine decarboxylase
U876_01015	ENOG4105C8Q	Methyl-accepting chemotaxis
U876_01030	ENOG4108I6A	alcohol dehydrogenase
U876_01035	ENOG4108IIE	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
U876_01040	ENOG4105C15	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
U876_01050	ENOG4105WWK	YheO domain protein
U876_01055	ENOG4105CEM	UPF0597 protein
U876_01065	ENOG4107QMW	pyridine nucleotide-disulfide oxidoreductase
U876_01070	ENOG4106SNF	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
U876_01075	ENOG4105C34	Pseudouridine synthase
U876_01080	ENOG4105DBW	Multi-copper polyphenol oxidoreductase laccase
U876_01085	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
U876_01090	ENOG4107T8T	UPF0173 metal-dependent hydrolase
U876_01095	ENOG4105CU9	asparagine synthetase A
U876_01100	ENOG4108VVK	transcriptional Regulator, AsnC
U876_01115	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
U876_01120	ENOG410642E	Short chain dehydrogenase
U876_01135	ENOG4107WP9	Histidine kinase
U876_01145	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
U876_01150	ENOG4108UQ5	membrane protein YcdZ
U876_01165	ENOG4105DQ2	Is probably involved in the electron transfer between its heme and the molybdenum cofactor of the reductase catalytic subunit YedY (By similarity)
U876_01180	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
U876_01185	ENOG4105IFJ	Histidine kinase
U876_01195	ENOG4107QY8	reductase
U876_01200	ENOG4105CUW	cytochrome C-TYPE protein
U876_01205	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
U876_01220	ENOG4105E7U	AraC family transcriptional regulator
U876_01230	ENOG4107ZYR	domain protein
U876_01235	ENOG4105D4A	Cell wall formation (By similarity)
U876_01240	ENOG4105HJX	Biotin- acetyl-CoA-carboxylase ligase
U876_01245	ENOG4105CS9	pantothenic acid kinase
U876_01260	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
U876_01270	ENOG4105PM1	preprotein translocase subunit SecE
U876_01275	ENOG4105E5V	Participates in transcription elongation, termination and antitermination (By similarity)
U876_01280	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
U876_01285	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
U876_01290	ENOG4108VZM	50s ribosomal protein L10
U876_01295	ENOG4105KBC	Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity)
U876_01300	ENOG4108IIJ	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
U876_01305	ENOG4105D27	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
U876_01315	ENOG4105WWK	YheO domain protein
U876_01320	ENOG4105KME	endoribonuclease L-psp
U876_01330	ENOG4108ZKU	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions (By similarity)
U876_01335	ENOG4105YKK	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions (By similarity)
U876_01340	ENOG4108UKE	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity)
U876_01345	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
U876_01350	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
U876_01355	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
U876_01360	ENOG4108ZI0	d,d-heptose 1,7-bisphosphate phosphatase
U876_01390	ENOG4105C7N	Xanthine uracil vitamin C permease
U876_01395	ENOG4105CMT	Dihydroxyacetone kinase
U876_01400	ENOG4108UTZ	Dihydroxyacetone kinase
U876_01415	ENOG4108JU9	GAF modulated sigma54 specific transcriptional regulator Fis family
U876_01420	ENOG4105ETT	transcriptional Regulator, LysR family
U876_01425	ENOG4105DWY	Agmatine deiminase
U876_01430	ENOG4105EMU	Dehydrogenase
U876_01435	ENOG4105IPI	Membrane
U876_01465	ENOG4105CH6	catalase
U876_01470	ENOG4105WCN	acetyltransferase
U876_01490	ENOG4105BZU	Histidine kinase
U876_01500	ENOG4108IJ6	ABC transporter
U876_01510	ENOG4105E4X	binding-protein-dependent transport systems inner membrane Component
U876_01535	ENOG4105CWB	LysR family transcriptional Regulator
U876_01545	ENOG4105C2I	pirin domain protein
U876_01550	ENOG4108VBZ	doxx family
U876_01555	ENOG4105DSY	exodeoxyribonuclease V, gamma
U876_01560	ENOG4107QKA	exodeoxyribonuclease V beta
U876_01565	ENOG4107QYX	exodeoxyribonuclease v alpha
U876_01575	ENOG4105KHA	Glyoxalase Bleomycin resistance protein (Dioxygenase
U876_01605	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
U876_01610	ENOG4105E0F	Histidine kinase
U876_01620	ENOG4105D05	Receptor
U876_01625	ENOG4105VEQ	Cold shock protein
U876_01635	ENOG41076HS	cation diffusion facilitator family transporter
U876_01650	ENOG4108UUM	single-stranded DNA-binding protein
U876_01655	ENOG41086KC	Transcriptional regulator
U876_01660	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
U876_01675	ENOG4105EIF	outer membrane protein W
U876_01680	ENOG4105C8Q	Methyl-accepting chemotaxis
U876_01700	ENOG4105SYT	Methylenetetrahydrofolate reductase
U876_01710	ENOG4105DKK	Benzoate
U876_01715	ENOG4108JCI	Transcriptional regulator
U876_01745	ENOG41090HJ	UPF0265 protein
U876_01755	ENOG4105N42	UPF0307 protein
U876_01760	ENOG4105CMS	peptidase U62, modulator of DNA gyrase
U876_01765	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
U876_01770	ENOG4105VFK	BolA family
U876_01780	ENOG4105E3I	toluene tolerance
U876_01785	ENOG4107PE3	Mammalian cell entry related domain protein
U876_01790	ENOG4105CY3	ABC transporter, permease
U876_01795	ENOG4105DHJ	ABC, transporter
U876_01800	ENOG4105C2X	Arabinose 5-phosphate isomerase
U876_01805	ENOG4108Z4R	3-deoxy-d-manno-octulosonate 8-phosphate phosphatase
U876_01810	ENOG4108P1K	Required for the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane (By similarity)
U876_01815	ENOG4105WI0	lipopolysaccharide transport periplasmic protein lptA
U876_01820	ENOG4108IUZ	ABC transporter
U876_01825	ENOG4105DTW	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
U876_01830	ENOG41080QH	sigma 54 modulation protein ribosomal protein S30EA
U876_01835	ENOG4107RM2	PTS IIA-like nitrogen-regulatory protein PtsN
U876_01840	ENOG4105C21	Displays ATPase and GTPase activities (By similarity)
U876_01845	ENOG41080Z8	PHOSPHOCARRIER protein
U876_01850	ENOG4105EMD	TRANSCRIPTIONal
U876_01865	ENOG41069H0	dihydroorotase EC 3.5.2.3
U876_01895	ENOG4105C0H	protease
U876_01900	ENOG4105C0H	protease
U876_01910	ENOG4105D6Z	AFG1 family ATPase
U876_01915	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
U876_01920	ENOG4108UJD	30S ribosomal protein S9
U876_01925	ENOG4108R5F	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
U876_01930	ENOG4105DJ5	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
U876_01935	ENOG4105EIX	cytochrome c1
U876_01940	ENOG4107MKT	Stringent starvation protein a
U876_01945	ENOG4105KB2	stringent starvation protein b
U876_01950	ENOG4105W4M	Transport-associated protein
U876_01955	ENOG4105F55	Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate (By similarity)
U876_01960	ENOG41082RQ	UPF0102 protein
U876_01965	ENOG4105E1C	Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1A (PBP1a) (By similarity)
U876_01970	ENOG4105CU0	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity)
U876_01975	ENOG4108V6E	Cell division protein mraZ
U876_01980	ENOG4105CGJ	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity)
U876_01985	ENOG41063Y6	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity)
U876_01990	ENOG4105CJN	penicillin-binding protein
U876_01995	ENOG4107EEN	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity)
U876_02000	ENOG4108EQQ	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein (By similarity)
U876_02005	ENOG4105CPY	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity)
U876_02010	ENOG4105DMZ	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity)
U876_02015	ENOG4105CNI	cell division protein FtsW
U876_02020	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
U876_02025	ENOG4105DFU	Cell wall formation (By similarity)
U876_02030	ENOG4105K7E	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly (By similarity)
U876_02035	ENOG4105CIT	This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity)
U876_02040	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
U876_02045	ENOG4105C7C	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
U876_02055	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
U876_02065	ENOG4105EJF	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity)
U876_02070	ENOG41067SF	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase (By similarity)
U876_02075	ENOG4105DHA	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity (By similarity)
U876_02090	ENOG4105D7Q	type ii secretion system
U876_02095	ENOG4107QHF	type ii secretion system protein e
U876_02105	ENOG4105D18	nicotinate-nucleotide pyrophosphorylase
U876_02120	ENOG41073TP	transcriptional regulator
U876_02125	ENOG4105DAQ	Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) (By similarity)
U876_02130	ENOG4107QSN	dihydrolipoamide acetyltransferase
U876_02135	ENOG4107QN2	dihydrolipoyl dehydrogenase
U876_02140	ENOG4105BZU	Histidine kinase
U876_02150	ENOG4108N3W	hemolysin secretion protein
U876_02155	ENOG4108N3W	hemolysin secretion protein
U876_02160	ENOG4105D78	K07001 NTE family protein
U876_02165	ENOG4107QIJ	Aconitate hydratase 2
U876_02180	ENOG4105E82	cytochrome subunit of dehydrogenase
U876_02190	ENOG4105CKI	cobalamin synthesis protein
U876_02195	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
U876_02205	ENOG4105K8U	2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
U876_02210	ENOG4107ZVW	dihydroneopterin aldolase
U876_02215	ENOG4105K7Z	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP (By similarity)
U876_02255	ENOG4105DWD	nucleoside recognition domain protein
U876_02260	ENOG4107R88	Chemotaxis protein (CheV)
U876_02265	ENOG410904N	short-chain dehydrogenase reductase
U876_02270	ENOG4105E0I	Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of tRNA(Met), by using acetyl-CoA as an acetyl donor and ATP (or GTP) (By similarity)
U876_02285	ENOG4108UQY	Iron-storage protein
U876_02295	ENOG4108Z5K	methylglyoxal synthase
U876_02310	ENOG4105HDK	L-asparaginase
U876_02325	ENOG4105D4X	repressor
U876_02330	ENOG4105C5Y	PTS System
U876_02335	ENOG4105CG3	alpha amylase, catalytic region
U876_02340	ENOG4108UW5	maltose o-acetyltransferase
U876_02350	ENOG4107AQZ	Membrane
U876_02360	ENOG4105C26	Dehydrogenase
U876_02365	ENOG4105NRK	Binding-protein-dependent transport systems, inner membrane component
U876_02370	ENOG4105D81	ABC transporter, permease
U876_02375	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
U876_02380	ENOG4107TYH	extracellular solute-binding protein family 1
U876_02385	ENOG4108M0I	Transcriptional regulator
U876_02390	ENOG4105DFD	Na H antiporter
U876_02430	ENOG4105CXW	Synthesizes alpha-1,4-glucan chains using ADP-glucose (By similarity)
U876_02435	ENOG4107QQ4	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans (By similarity)
U876_02440	ENOG4105D8J	Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle (By similarity)
U876_02445	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
U876_02460	ENOG4107VXZ	Hydrolase
U876_02465	ENOG4105KW8	RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity)
U876_02470	ENOG4105F1S	paraquat-inducible protein a
U876_02475	ENOG4105DY2	Paraquat-inducible protein b
U876_02480	ENOG4108Q2G	(LipO)protein
U876_02485	ENOG4105UYK	outer membrane protein a
U876_02500	ENOG4105H4F	exported protein
U876_02510	ENOG4105KMG	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes (By similarity)
U876_02515	ENOG4105CEN	a g-specific adenine glycosylase
U876_02535	ENOG4105D4J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
U876_02550	ENOG41067MG	lrgb family
U876_02560	ENOG4105CMU	LysR family (Transcriptional regulator
U876_02585	ENOG4108Z66	YbaK ebsC protein
U876_02590	ENOG4105CJ3	phosphate transporter
U876_02595	ENOG4107IX6	phosphate transport regulator
U876_02610	ENOG4105D1S	lipid A biosynthesis
U876_02615	ENOG4105DW0	Catalyzes the ADP transfer to D-glycero-D-manno-heptose 1-phosphate, yielding ADP-D,D-heptose (By similarity)
U876_02620	ENOG4105DFG	type I secretion outer membrane protein
U876_02625	ENOG41087AY	ADP-Ribose pyrophosphatase
U876_02630	ENOG4108SX3	cytoplasmic protein
U876_02635	ENOG41070EG	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes (By similarity)
U876_02640	ENOG4105IPS	esterase
U876_02660	ENOG4105Y49	secretion protein, HlyD family
U876_02665	ENOG4105DSW	Fusaric acid resistance protein
U876_02670	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
U876_02675	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
U876_02710	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
U876_02715	ENOG4105N2G	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
U876_02740	ENOG4107S7E	1-acyl-sn-glycerol-3-phosphate acyltransferase
U876_02745	ENOG41087YS	Phage shock protein A
U876_02760	ENOG41082IR	Excinuclease ABC C subunit domain protein
U876_02770	ENOG4105FR1	rard protein
U876_02775	ENOG4108RG0	uracil-dna glycosylase
U876_02790	ENOG4105FAV	ABC, transporter
U876_02795	ENOG4105FDK	ABC transporter
U876_02800	ENOG4105NXV	High-affinity zinc uptake system protein
U876_02820	ENOG4105DR5	peptidase
U876_02830	ENOG4105R2J	Conserved Protein
U876_02850	ENOG4105D86	that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity)
U876_02870	ENOG4107TH8	cina domain protein
U876_02875	ENOG4105C68	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity)
U876_02885	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
U876_02890	ENOG4105CFH	Aspartokinase
U876_02895	ENOG4105VM8	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding (By similarity)
U876_02930	ENOG41061WM	D-Alanyl-D-Alanine
U876_02935	ENOG4106W5V	Membrane
U876_02945	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
U876_02950	ENOG4105MYG	DNA polymerase iii, chi subunit
U876_02955	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
U876_02960	ENOG4108M8S	permease YjgP YjgQ family protein
U876_02970	ENOG4108K5H	permease YjgP YjgQ family protein
U876_02985	ENOG4105DFP	Integrase
U876_03000	ENOG4105XB7	anti-repressor protein
U876_03035	ENOG4105BZU	Histidine kinase
U876_03040	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
U876_03050	ENOG4105EYA	deoxyribonuclease
U876_03055	ENOG4105D9N	nucleoside
U876_03065	ENOG4105FCI	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate (By similarity)
U876_03070	ENOG4105CMW	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis (By similarity)
U876_03075	ENOG4105CZG	Phosphotransfer between the C1 and C5 carbon atoms of pentose (By similarity)
U876_03080	ENOG4105D3A	purine nucleoside phosphorylase DeoD-type
U876_03085	ENOG4105BZU	Histidine kinase
U876_03095	ENOG4105EAC	phosphoserine phosphatase
U876_03110	ENOG4105DNJ	May play a role in the repair of endogenous alkylation damage (By similarity)
U876_03120	ENOG4108ZVW	Anti-RNA polymerase sigma 70 factor
U876_03125	ENOG4105K70	DNA-binding protein
U876_03140	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
U876_03145	ENOG4105MYN	Zinc uptake regulation protein
U876_03160	ENOG4105CWM	branched-chain amino acid transport system II carrier protein
U876_03165	ENOG4105CWM	branched-chain amino acid transport system II carrier protein
U876_03170	ENOG4107S47	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC) (By similarity)
U876_03175	ENOG4105C1J	atp-dependent rna helicase
U876_03180	ENOG4105D1Q	UPF0246 protein
U876_03185	ENOG4105CZX	twitching motility protein
U876_03190	ENOG4105CZX	twitching motility protein
U876_03195	ENOG4105DFA	alanine racemase domain protein
U876_03200	ENOG4105II7	pyrroline-5-carboxylate reductase
U876_03205	ENOG4108VIA	integral membrane protein
U876_03210	ENOG4105VZ9	UPF0235 protein
U876_03225	ENOG4107QSI	ABC, transporter
U876_03235	ENOG4105EQK	-acetyltransferase
U876_03240	ENOG4106WH9	Protein of unknown function (DUF2753)
U876_03245	ENOG4105E39	Enoyl-CoA hydratase
U876_03260	ENOG4108RZ4	Short-chain dehydrogenase reductase Sdr
U876_03265	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
U876_03270	ENOG4105C8Q	Methyl-accepting chemotaxis
U876_03275	ENOG4105KA4	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity)
U876_03280	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
U876_03285	ENOG4105C4M	(Ubiquinol oxidase) subunit I
U876_03290	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
U876_03300	ENOG4105KJB	cyd operon protein YbgE
U876_03305	ENOG4107YD3	Thioesterase
U876_03310	ENOG4105E02	MotA TolQ exbB proton channel
U876_03315	ENOG4105M8F	Biopolymer transport protein exbD tolR
U876_03325	ENOG4107R6Y	Involved in the TonB-independent uptake of proteins (By similarity)
U876_03330	ENOG4105KCK	Peptidoglycan-associated lipoprotein
U876_03335	ENOG4105UFD	tol-pal system protein YbgF
U876_03350	ENOG4105C8Q	Methyl-accepting chemotaxis
U876_03355	ENOG4105D0I	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate (By similarity)
U876_03360	ENOG4105DSB	aldose 1-epimerase
U876_03370	ENOG4107RTM	4-alpha-glucanotransferase (EC 2.4.1.25)
U876_03375	ENOG4105C9C	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity)
U876_03385	ENOG4105E0X	reductase
U876_03395	ENOG4105EJF	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity)
U876_03400	ENOG4105CJH	Alcohol dehydrogenase zinc-binding domain protein
U876_03405	ENOG4108ZHJ	Organic hydroperoxide resistance protein
U876_03410	ENOG4105K56	Transcriptional regulator
U876_03425	ENOG4105EW9	transcriptional regulator AsnC family
U876_03440	ENOG4108K4B	hydrolase
U876_03455	ENOG4105C8J	)-transporter
U876_03465	ENOG4105C8J	)-transporter
U876_03490	ENOG4107SQD	Transcriptional regulator, GntR family
U876_03510	ENOG4105E3B	Multicopper oxidase
U876_03520	ENOG4105XEP	YhcH YjgK YiaL family protein
U876_03530	ENOG4105CUY	Mechanosensitive ion channel
U876_03535	ENOG4107N1Q	ErfK YbiS YcfS YnhG family protein
U876_03540	ENOG4105CK7	Sodium proline symporter
U876_03585	ENOG4105EQ2	LysR family Transcriptional regulator
U876_03590	ENOG4105D6S	protein involved in catabolism of external DNA
U876_03600	ENOG4105C5H	ABC transporter
U876_03605	ENOG4105C2X	Arabinose 5-phosphate isomerase
U876_03610	ENOG4105G5H	Membrane
U876_03615	ENOG4107QX8	SPFH domain, Band 7 family protein
U876_03620	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
U876_03625	ENOG4105C11	sulfate adenylyltransferase), subunit 2
U876_03630	ENOG4105C3T	may be the GTPase, regulating ATP sulfurylase activity (By similarity)
U876_03640	ENOG4108I67	Catalyzes the synthesis of activated sulfate (By similarity)
U876_03660	ENOG4107RHT	methyl-accepting chemotaxis sensory transducer with Pas Pac sensor
U876_03695	ENOG4108UUE	Transcriptional regulator
U876_03710	ENOG4105F0N	pyrophosphate phospho-hydrolase
U876_03715	ENOG4105DFU	Cell wall formation (By similarity)
U876_03720	ENOG4108UMA	3-octaprenyl-4-hydroxybenzoate carboxy-lyase
U876_03725	ENOG410630P	Transcriptional regulator
U876_03730	ENOG4108UGV	hypoxanthine phosphoribosyltransferase
U876_03735	ENOG4105DA5	(ABC) transporter
U876_03740	ENOG4105E3A	(ABC) transporter
U876_03745	ENOG4105DCU	2-hydroxyglutaryl-CoA dehydratase
U876_03750	ENOG4105CIZ	coA-substrate-specific enzyme activase
U876_03770	ENOG4108IAA	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate (By similarity)
U876_03775	ENOG4105CCG	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is tranferred onto alpha-ketoisovalerate to form ketopantoate (By similarity)
U876_03780	ENOG4105K8U	2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
U876_03785	ENOG4105DJ0	Poly(A) Polymerase
U876_03790	ENOG4106F3G	Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon (By similarity)
U876_03795	ENOG4108V7X	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
U876_03800	ENOG4105PW4	Sugar fermentation stimulation protein homolog
U876_03810	ENOG4105CQ7	ATP-dependent helicase
U876_03815	ENOG4105BZ4	penicillin-binding protein
U876_03820	ENOG4108YZK	glyoxalase bleomycin resistance protein dioxygenase
U876_03825	ENOG4108ZBZ	Catalyzes the excretion of spermidine (By similarity)
U876_03830	ENOG41090TI	Catalyzes the excretion of spermidine (By similarity)
U876_03840	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
U876_03850	ENOG41076MN	Phosphoesterase, PA-phosphatase related
U876_03865	ENOG4105CDM	Glutamate-1-semialdehyde aminotransferase
U876_03870	ENOG4105CMQ	Chloride channel
U876_03880	ENOG4108YX9	iron--sulfur cluster insertion protein erpA
U876_03905	ENOG4108NIW	Leucine export protein LeuE
U876_03910	ENOG4105VY0	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters (By similarity)
U876_03915	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
U876_03925	ENOG4107V40	secretion protein, HlyD family
U876_03955	ENOG4105I93	response regulator
U876_03960	ENOG4105DUX	Transporter
U876_03965	ENOG4105C3Y	UTP-glucose-1-phosphate uridylyltransferase
U876_03970	ENOG41083P1	competence protein ComEA helix-hairpin-helix repeat protein
U876_03975	ENOG4108RNI	3'(2')5'-bisphosphate nucleotidase
U876_03980	ENOG4105K9H	YciI-like protein
U876_03985	ENOG4107835	probably involved in intracellular septation (By similarity)
U876_03990	ENOG4105DY8	decarboxylase
U876_03995	ENOG4108UT2	hemolysin iii
U876_04000	ENOG4105D0C	transport protein
U876_04015	ENOG4107R88	Chemotaxis protein (CheV)
U876_04020	ENOG4108UJV	acyl-CoA thioesterase i
U876_04025	ENOG4108I0Y	(ABC) transporter
U876_04030	ENOG4105CV6	ABC transporter, permease
U876_04035	ENOG4105ECP	epimerase
U876_04040	ENOG4105BZU	Histidine kinase
U876_04045	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
U876_04050	ENOG4105IIU	Aminopeptidase
U876_04055	ENOG4105CZ1	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity)
U876_04060	ENOG41090ED	Protein with unknown function (DUF469)
U876_04065	ENOG4105CSV	Glutaminase
U876_04070	ENOG4107RM6	sulfurtransferase
U876_04075	ENOG4105RX7	peptidase S8 and S53, subtilisin, kexin, sedolisin
U876_04080	ENOG4105SUV	lipoprotein YgdR
U876_04085	ENOG4105BZ1	(ABC) transporter
U876_04110	ENOG4107G87	m6 family metalloprotease domain protein
U876_04115	ENOG4105KQT	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome (By similarity)
U876_04120	ENOG4105BZU	Histidine kinase
U876_04140	ENOG4105VYA	Uncharacterized conserved protein (DUF2132)
U876_04145	ENOG4105DJ4	phosphatidylserine decarboxylase
U876_04150	ENOG4105E06	May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity)
U876_04155	ENOG4108RBP	3'-to-5' exoribonuclease specific for small oligoribonucleotides (By similarity)
U876_04185	ENOG4105VEQ	Cold shock protein
U876_04195	ENOG4105C8Q	Methyl-accepting chemotaxis
U876_04200	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
U876_04255	ENOG4109015	Biopolymer transport protein exbD tolR
U876_04275	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
U876_04280	ENOG4108I5X	binding-protein-dependent transport systems inner membrane Component
U876_04285	ENOG4108IYQ	Binding-protein-dependent transport systems inner membrane component
U876_04300	ENOG4108JQ7	(ABC) transporter
U876_04310	ENOG4105CIN	aminoacyl-histidine dipeptidase
U876_04315	ENOG4105DYA	Acts on guanine, xanthine and to a lesser extent hypoxanthine (By similarity)
U876_04320	ENOG4105V1F	Fermentation respiration switch protein
U876_04325	ENOG4108UVK	Binds to the sigma-S subunit of RNA polymerase, activating expression of sigma-S-regulated genes. Stimulates RNA polymerase holoenzyme formation and may bind to several other sigma factors, such as sigma-70 and sigma-32 (By similarity)
U876_04335	ENOG4105C2S	Catalyzes the NADPH dependent reduction of L-gamma- glutamyl 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate (By similarity)
U876_04365	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
U876_04375	ENOG4105D7T	ABC transporter
U876_04380	ENOG4105DG7	nitrate ABC transporter
U876_04385	ENOG4105D7T	ABC transporter
U876_04390	ENOG4107QZF	nitrite reductase NADPH large subunit
U876_04395	ENOG4107QZF	nitrite reductase NADPH large subunit
U876_04400	ENOG4105DD7	kinase (PfkB family
U876_04405	ENOG4105D53	Catalyzes the hydrolysis of pseudouridine 5'-phosphate (PsiMP) to ribose 5-phosphate and uracil (By similarity)
U876_04415	ENOG4105CA0	peroxidase
U876_04450	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
U876_04480	ENOG4105C84	Histidine ammonia-lyase
U876_04505	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
U876_04515	ENOG4105C2D	reductase
U876_04520	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
U876_04530	ENOG4108RIR	Molybdenum cofactor biosynthesis protein
U876_04540	ENOG4105DWK	Membrane
U876_04545	ENOG4107XM3	UPF0442 protein
U876_04555	ENOG4108IJ7	Glycine betaine
U876_04560	ENOG4108HQS	Glycine betaine
U876_04565	ENOG4105GIJ	Glycine betaine
U876_04570	ENOG4105ET3	Reduction of activated sulfate into sulfite (By similarity)
U876_04575	ENOG4105ET1	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate (By similarity)
U876_04580	ENOG4107EER	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity)
U876_04585	ENOG4107TIF	Phenazine biosynthesis protein, PhzF family
U876_04590	ENOG4105CRK	lysyL-tRNA synthetase
U876_04595	ENOG4105CG1	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA (By similarity)
U876_04600	ENOG4105C8Q	Methyl-accepting chemotaxis
U876_04605	ENOG4105D6U	Sodium Glutamate Symporter
U876_04610	ENOG4105HDK	L-asparaginase
U876_04615	ENOG4105VUT	cytoplasmic protein
U876_04635	ENOG4105D07	Signal peptide peptidase, SppA
U876_04640	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
U876_04645	ENOG41069NU	Nitroreductase
U876_04660	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
U876_04665	ENOG4105CIS	alcohol dehydrogenase
U876_04670	ENOG4105HEI	LysR family (Transcriptional regulator
U876_04675	ENOG4105CI1	PTS System
U876_04680	ENOG4108IA2	Sodium pantothenate symporter
U876_04690	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
U876_04695	ENOG4105KM4	Acetyl-CoA carboxylase, biotin carboxyl carrier protein
U876_04700	ENOG4108Z38	Catalyzes a trans-dehydration via an enolate intermediate (By similarity)
U876_04710	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
U876_04720	ENOG4105BZU	Histidine kinase
U876_04740	ENOG4109039	Involved in the biogenesis of TorA. Acts on TorA before the insertion of the molybdenum cofactor and, as a result, probably favors a conformation of the apoenzyme that is competent for acquiring the cofactor (By similarity)
U876_04755	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
U876_04770	ENOG4108Z11	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes (By similarity)
U876_04775	ENOG4105D1W	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity)
U876_04795	ENOG4108UTT	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity)
U876_04800	ENOG4107YIM	Involved in the transcription termination process (By similarity)
U876_04805	ENOG4105CG2	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity)
U876_04810	ENOG4108ZAI	phosphatidylglycerophosphatase a
U876_04815	ENOG4108JQ6	ABC transporter
U876_04825	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
U876_04835	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
U876_04840	ENOG4105CTB	Polyprenyl synthetase
U876_04845	ENOG41067QG	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
U876_04850	ENOG4105E14	MotA TolQ exbB proton channel
U876_04855	ENOG4107XSU	flagellar motor protein motb
U876_04860	ENOG4108UKH	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
U876_04870	ENOG4105HBR	Rna-binding protein
U876_04875	ENOG4105F7M	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit (By similarity)
U876_04880	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
U876_04885	ENOG4105EEI	dihydropteroate synthase
U876_04890	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
U876_04895	ENOG4105CP7	Triose-phosphate isomerase
U876_04915	ENOG4105K7D	Required for maturation of 30S ribosomal subunits (By similarity)
U876_04920	ENOG4105CHV	Transcription elongation factor NusA
U876_04925	ENOG4107QHU	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
U876_04930	ENOG4105KG7	Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity)
U876_04935	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
U876_04940	ENOG4105K77	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity)
U876_04945	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
U876_04955	ENOG4105BZU	Histidine kinase
U876_04960	ENOG41090EX	DsrE family
U876_04975	ENOG4105EQ6	Hydrolyzes dipeptides containing N-terminal aspartate residues. May play a role in allowing the cell to use peptide aspartate to spare carbon otherwise required for the synthesis of the aspartate family of amino acids (By similarity)
U876_04985	ENOG4108NEV	two component transcriptional regulator, LytTR family
U876_04995	ENOG4108ZXC	Two component transcriptional regulator, luxr family
U876_05000	ENOG4105BZU	Histidine kinase
U876_05005	ENOG4105QA4	4Fe-4S Ferredoxin, iron-sulfur binding domain protein
U876_05010	ENOG4106WHD	Tetrathionate reductase
U876_05015	ENOG4105DB1	molybdopterin oxidoreductase
U876_05050	ENOG4107N1Q	ErfK YbiS YcfS YnhG family protein
U876_05070	ENOG41071R3	Low-potential electron donor to a number of redox enzymes (By similarity)
U876_05075	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
U876_05080	ENOG4105M2E	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell (By similarity)
U876_05085	ENOG4105T95	Thiol disulfide interChange protein
U876_05090	ENOG4105C2R	Single-stranded-DNA-specific exonuclease (RecJ)
U876_05095	ENOG4107SWG	transcriptional regulator MERR family
U876_05110	ENOG4108IUB	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
U876_05115	ENOG4105MJ9	esterase
U876_05125	ENOG4105C0G	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity)
U876_05135	ENOG4108BDP	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity)
U876_05140	ENOG4108Z43	UPF0250 protein
U876_05145	ENOG4105DZ1	carboxypeptidase
U876_05150	ENOG4105K6T	rare lipoprotein A
U876_05155	ENOG4105CVE	Lytic murein transglycosylase
U876_05165	ENOG4105CNI	cell division protein FtsW
U876_05170	ENOG4105CJN	penicillin-binding protein
U876_05175	ENOG4108UXA	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA (By similarity)
U876_05180	ENOG4105KEM	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation (By similarity)
U876_05185	ENOG4108Z1W	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity)
U876_05200	ENOG4105C8T	Leucyl-tRNA synthetase
U876_05205	ENOG4107PAI	alpha helical protein
U876_05210	ENOG4105CE8	Transfers the fatty acyl group on membrane lipoproteins (By similarity)
U876_05215	ENOG4108JU5	Magnesium and cobalt efflux protein
U876_05220	ENOG4105KGE	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA (By similarity)
U876_05225	ENOG4105C9A	Phoh family
U876_05230	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
U876_05235	ENOG4105EAK	ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family
U876_05240	ENOG4106XMA	In vivo, quickly hydrolyzes the ureidoacrylate peracid to avoid toxicity, but can also hydrolyzes ureidoacrylate that is formed spontaneously from ureidoacrylate peracid. One of the products of hydrolysis, carbamate, hydrolyzes spontaneously, thereby releasing one of the pyrimidine rings nitrogen atoms as ammonia and one of its carbons as CO2 (By similarity)
U876_05250	ENOG4105BZU	Histidine kinase
U876_05265	ENOG4105EVE	HAD-superfamily hydrolase subfamily IA variant 3
U876_05275	ENOG4105BZU	Histidine kinase
U876_05285	ENOG4105C5I	Dehydrogenase
U876_05295	ENOG4108R5S	membrane
U876_05300	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
U876_05310	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
U876_05320	ENOG4105DHQ	Histidine kinase
U876_05325	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
U876_05360	ENOG4105T0Z	Conserved Protein
U876_05380	ENOG4108VP9	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane (By similarity)
U876_05385	ENOG4108WJH	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane (By similarity)
U876_05390	ENOG4105E33	succinate dehydrogenase
U876_05400	ENOG4105C8Q	Methyl-accepting chemotaxis
U876_05405	ENOG4108QXE	glycerophosphoryl diester phosphodiesterase
U876_05410	ENOG4105EGS	Mechanosensitive ion channel
U876_05420	ENOG4105DR5	peptidase
U876_05435	ENOG4105EJC	lysr family transcriptional regulator
U876_05450	ENOG4105C8Q	Methyl-accepting chemotaxis
U876_05455	ENOG4105C5Q	Transcriptional regulator
U876_05460	ENOG4108JQC	penicillin-binding protein 1A
U876_05485	ENOG4105E4G	Type IV pilus
U876_05490	ENOG4105KHV	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
U876_05495	ENOG4105D49	3-dehydroquinate synthase
U876_05505	ENOG4105DFE	Dna adenine methylase
U876_05510	ENOG4105DJV	ribulose-phosphate 3-epimerase
U876_05515	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
U876_05520	ENOG4105C31	Tryptophanyl-tRNA synthetase
U876_05535	ENOG4105C8Y	Acetylornithine aminotransferase
U876_05545	ENOG4105C26	Dehydrogenase
U876_05555	ENOG4107VXZ	Hydrolase
U876_05565	ENOG4105D95	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin (By similarity)
U876_05585	ENOG41060QA	UPF0267 protein
U876_05595	ENOG4108I5U	Uridine phosphorylase
U876_05600	ENOG4106Z1T	Nicotinamide Mononucleotide Transporter
U876_05605	ENOG4107QWE	)-transporter
U876_05650	ENOG4105C3G	gtp-binding protein
U876_05655	ENOG4108ZPD	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity)
U876_05660	ENOG4105CGH	5'-nucleotidase
U876_05665	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
U876_05675	ENOG4105CTR	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol (By similarity)
U876_05680	ENOG4105C1U	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein (By similarity)
U876_05685	ENOG4105C7E	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) (By similarity)
U876_05690	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
U876_05695	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
U876_05705	ENOG41063JG	Transcriptional regulator
U876_05710	ENOG4105CXR	Phospho-2-dehydro-3-deoxyoctonate aldolase
U876_05715	ENOG4105CK2	sodium dicarboxylate symporter
U876_05720	ENOG4108VKA	Acts as a radical domain for damaged PFL and possibly other radical proteins (By similarity)
U876_05725	ENOG4105D5S	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine (By similarity)
U876_05740	ENOG4105CW3	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
U876_05745	ENOG4105BZG	amino acid carrier protein
U876_05750	ENOG4105F8C	transglutaminase domain-containing protein
U876_05760	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
U876_05765	ENOG41066YJ	Beta-lactamase
U876_05770	ENOG4105DUX	Transporter
U876_05775	ENOG4107Y66	Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity)
U876_05780	ENOG4108UJU	UPF0301 protein
U876_05790	ENOG4105D7Z	glutathione synthase
U876_05795	ENOG4105QF0	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity)
U876_05805	ENOG4105GPY	SprT protein
U876_05810	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
U876_05815	ENOG4105CV1	Transketolase (EC 2.2.1.1)
U876_05840	ENOG4105KME	endoribonuclease L-psp
U876_05845	ENOG4105TMR	Functions as a holding molecular chaperone (holdase) which stabilizes unfolding intermediates and rapidly releases them in an active form once stress has abated. Plays an important role in protecting cells from severe heat shock and starvation, as well as in acid resistance of stationary-phase cells. It catalyzes the conversion of methylglyoxal (MG) to D-lactate in a single glutathione (GSH)-independent step (By similarity)
U876_05855	ENOG4105ED7	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling (By similarity)
U876_05870	ENOG4105DR5	peptidase
U876_05875	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
U876_05880	ENOG4107WCA	isomerase
U876_05890	ENOG4108V1U	phospholipid-binding protein
U876_05895	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
U876_05910	ENOG4105C87	Aminotransferase class I and II
U876_05920	ENOG4105C5Q	Transcriptional regulator
U876_05925	ENOG4105UBK	short-chain dehydrogenase reductase
U876_05930	ENOG4105ERU	peptidase
U876_05935	ENOG4105EY2	Catalyzes the hydrolysis of N(2)-succinylarginine into N(2)-succinylornithine, ammonia and CO(2) (By similarity)
U876_05940	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
U876_05955	ENOG4107RHT	methyl-accepting chemotaxis sensory transducer with Pas Pac sensor
U876_05965	ENOG4105E2D	ec 3.2.1.52
U876_05970	ENOG4105RD7	BadF BadG BcrA BcrD
U876_05980	ENOG4108JQ7	(ABC) transporter
U876_05990	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
U876_06000	ENOG4108J59	Extracellular solute-binding protein, family 5
U876_06005	ENOG4105BZU	Histidine kinase
U876_06025	ENOG4105XIQ	Protein of unknown function (DUF2517)
U876_06055	ENOG4107SDU	Methyl-accepting chemotaxis
U876_06065	ENOG4108ESY	Metal dependent phosphohydrolase
U876_06070	ENOG4105DR8	Membrane
U876_06075	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
U876_06080	ENOG4105C6R	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor (By similarity)
U876_06085	ENOG4108IUZ	ABC transporter
U876_06090	ENOG4107A5B	Binding-protein-dependent transport systems, inner membrane component
U876_06100	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
U876_06105	ENOG4105BZU	Histidine kinase
U876_06110	ENOG4105HD0	Transcriptional regulator of molybdate metabolism, LysR family
U876_06115	ENOG4107H9G	Necessary for formate dehydrogenase activity (By similarity)
U876_06155	ENOG4108IEG	Formate dehydrogenase Alpha subunit
U876_06155	ENOG4108IEG	Formate dehydrogenase Alpha subunit
U876_06160	ENOG4105QAX	Iron-sulfur
U876_06170	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
U876_06175	ENOG4107R1I	NAD-dependent malic enzyme
U876_06190	ENOG4105C2W	permease
U876_06195	ENOG4105HHQ	6-phosphogluconolactonase (EC 3.1.1.31)
U876_06205	ENOG4105EGS	Mechanosensitive ion channel
U876_06210	ENOG4105CA9	Pyruvate kinase
U876_06225	ENOG4105CKD	glutathione-regulated potassium-efflux system protein
U876_06240	ENOG4105DH7	May be involved in recombination (By similarity)
U876_06250	ENOG4107RH8	nuclease SbcCD subunit D
U876_06255	ENOG4105EYH	Exonuclease
U876_06260	ENOG4105EYH	Exonuclease
U876_06270	ENOG4105CPW	cytochrome b561
U876_06280	ENOG4105BZU	Histidine kinase
U876_06285	ENOG4105C5Y	PTS System
U876_06295	ENOG4105KZ7	phosphocarrier protein hpr
U876_06300	ENOG4105C6T	cysteine synthase
U876_06305	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
U876_06320	ENOG4108R96	Methyltransferase, YaeB family
U876_06340	ENOG4108JJ8	(ABC) transporter
U876_06345	ENOG4108JJ9	ABC, transporter
U876_06360	ENOG41065U4	response regulator
U876_06375	ENOG4108YYX	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. Modulates RNA-binding and helicase activities of the degradosome (By similarity)
U876_06395	ENOG4106FVC	RNA methyltransferase
U876_06405	ENOG4105D5I	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate (By similarity)
U876_06410	ENOG4105D98	threonine synthase
U876_06415	ENOG4108VSZ	Inherit from COG: ketosteroid isomerase-like protein
U876_06430	ENOG4105C5H	ABC transporter
U876_06450	ENOG4108QW8	Purine nucleoside phosphorylase deoD-type
U876_06465	ENOG4105BZU	Histidine kinase
U876_06470	ENOG4105C8E	extradiol ring-cleavage dioxygenase class IIi protein subunit b
U876_06480	ENOG4108V1T	peptidylprolyl cis-trans isomerase
U876_06495	ENOG4105CUB	amino acid
U876_06505	ENOG4105CUB	amino acid
U876_06515	ENOG4108JPW	Aminotransferase
U876_06520	ENOG4105C26	Dehydrogenase
U876_06525	ENOG4107VRI	Transcriptional regulator
U876_06530	ENOG4105CJP	fad dependent oxidoreductase
U876_06555	ENOG4105Q26	Siderophore-interacting protein
U876_06560	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
U876_06565	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
U876_06570	ENOG4105DJY	efflux transporter, rnd family, mfp subunit
U876_06580	ENOG4105E2M	Manganese-dependent inorganic pyrophosphatase
U876_06590	ENOG4105C4F	May be involved in recombinational repair of damaged DNA (By similarity)
U876_06595	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
U876_06600	ENOG4105K90	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
U876_06605	ENOG4105CFG	Acts as a chaperone (By similarity)
U876_06610	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
U876_06620	ENOG4105D7K	pfkb domain protein
U876_06635	ENOG4105WBN	Transcriptional regulator (LacI family
U876_06655	ENOG41080HT	Transcriptional regulator, arsr family
U876_06680	ENOG4105BZU	Histidine kinase
U876_06685	ENOG4107RMF	Catalyzes both the ATP-dependent activation of exogenously supplied lipoate to lipoyl-AMP and the transfer of the activated lipoyl onto the lipoyl domains of lipoate-dependent enzymes (By similarity)
U876_06705	ENOG4108IJF	Heavy metal efflux pump, CzcA
U876_06710	ENOG4105EP1	Efflux transporter rnd family, mfp subunit
U876_06730	ENOG4105CGK	Exodeoxyribonuclease III
U876_06790	ENOG4105E2S	oxidase) subunit II
U876_06795	ENOG4105BZ9	Cytochrome C oxidase, subunit I
U876_06800	ENOG4105CCU	oxidase (Subunit III)
U876_06805	ENOG41090KH	cytochrome o ubiquinol oxidase (subunit iv)
U876_06810	ENOG4105F1R	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group (By similarity)
U876_06815	ENOG4107RDB	Major Facilitator
U876_06825	ENOG4105E2B	Taurine dioxygenase
U876_06830	ENOG4105EUS	Binding-protein-dependent transport systems, inner membrane component
U876_06835	ENOG4108ETV	ABC transporter
U876_06840	ENOG4106FTQ	Taurine ABC transporter, periplasmic
U876_06850	ENOG4105D9N	nucleoside
U876_06875	ENOG4105S2T	inner membrane protein YbcI
U876_06885	ENOG4105F6H	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate (By similarity)
U876_06890	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
U876_06895	ENOG4105DK0	Indole-3-glycerol phosphate synthase
U876_06900	ENOG4108I0Q	anthranilate phosphoribosyltransferase
U876_06905	ENOG4108EFP	Anthranilate synthase component II
U876_06910	ENOG4105CRQ	synthase (Component I)
U876_06915	ENOG4105DB7	PHP domain protein
U876_06920	ENOG4107RTD	sua5 ycio yrdc ywlc family protein
U876_06930	ENOG4105K8I	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves (By similarity)
U876_06935	ENOG4105FE9	pseudouridine synthase
U876_06940	ENOG4105C29	acyl-CoA thioesterase
U876_06960	ENOG4108IG5	Transcriptional regulator
U876_06965	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
U876_06970	ENOG4105BZS	acriflavin resistance protein
U876_06975	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
U876_06980	ENOG4105C1B	dTDP-glucose 4-6-dehydratase
U876_06985	ENOG4105DBZ	Dtdp-4-dehydrorhamnose reductase
U876_06995	ENOG4108URP	Dtdp-4-dehydrorhamnose 3,5-epimerase
U876_07025	ENOG4105ESV	Glycosyl transferase, family 4
U876_07035	ENOG4105ESV	Glycosyl transferase, family 4
U876_07045	ENOG4107QQG	Dehydrogenase
U876_07055	ENOG4105C5E	polysaccharide biosynthesis protein
U876_07065	ENOG4105EAG	UDP-N-acetylglucosamine 2-epimerase
U876_07075	ENOG4105DAY	polysaccharide export protein
U876_07085	ENOG4105D75	Capsular exopolysaccharide family
U876_07095	ENOG4105E3R	(LipO)protein
U876_07105	ENOG4108YXG	UPF0502 protein
U876_07115	ENOG4105KR1	Trans-acting protein required for termination of DNA replication. Binds to DNA replication terminator sequences (terA to terF) to prevent the passage of replication forks. The termination efficiency will be affected by the affinity of this protein for the terminator sequence (By similarity)
U876_07130	ENOG4107RUY	(E1 component), alpha subunit
U876_07135	ENOG4105CPP	Dehydrogenase, E1 component
U876_07140	ENOG4107QSN	dihydrolipoamide acetyltransferase
U876_07145	ENOG4105VEQ	Cold shock protein
U876_07175	ENOG4108594	Permease of the drug metabolite transporter
U876_07180	ENOG4105N2W	Transcriptional regulator
U876_07185	ENOG4105C6N	Formate acetyltransferase
U876_07190	ENOG4105F1A	Pyruvate formate-lyase
U876_07195	ENOG4107T9Z	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
U876_07205	ENOG4105CPI	Metal Dependent Phosphohydrolase
U876_07210	ENOG4105I08	Pseudouridine synthase
U876_07220	ENOG4107QSI	ABC, transporter
U876_07225	ENOG4108RE9	Phosphodiesterase
U876_07240	ENOG4107ESN	Flagella basal body P-ring formation protein flgA
U876_07245	ENOG4107R88	Chemotaxis protein (CheV)
U876_07250	ENOG4105BZU	Histidine kinase
U876_07255	ENOG4105K88	Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body (By similarity)
U876_07260	ENOG4108ZC9	flagellar basal-body rod protein flgc
U876_07270	ENOG4105BZE	flagellar hook protein, FlgE
U876_07275	ENOG4108KPB	Flagellar basal-body rod protein FlgF
U876_07280	ENOG4105CGA	flagellar basal-body rod protein FlgG
U876_07285	ENOG4107W7W	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity)
U876_07290	ENOG4105D92	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity)
U876_07295	ENOG4108ZW7	flagellar rod assembly protein muramidase flgj
U876_07300	ENOG4105E1Q	flagellar hook-associated protein
U876_07305	ENOG4105DTJ	flagellar hook-associated protein
U876_07310	ENOG4105CJW	magnesium transporter
U876_07315	ENOG4105C9X	ppx gppa phosphatase
U876_07320	ENOG4105CUU	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) (By similarity)
U876_07325	ENOG4105RH4	Glycine cleavage system transcriptional repressor
U876_07335	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
U876_07340	ENOG4105BZU	Histidine kinase
U876_07345	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
U876_07350	ENOG4107QNR	UPF0135 protein
U876_07355	ENOG4108V3E	phosphoribosylglycinamide formyltransferase
U876_07360	ENOG4105CXB	phosphoribosylaminoimidazole synthetase
U876_07365	ENOG4105CZ5	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate (By similarity)
U876_07380	ENOG4108I9X	Isocitrate lyase
U876_07385	ENOG4107QP3	malate synthase g
U876_07400	ENOG4108Z6B	deaminase
U876_07405	ENOG4105C8U	phosphate abc transporter
U876_07410	ENOG4105E2Z	phosphate ABC transporter (Permease
U876_07415	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
U876_07430	ENOG4105C37	(CBS) domain
U876_07440	ENOG4105C3R	Methionine synthase
U876_07445	ENOG4105D5Q	Arginine ornithine antiporter
U876_07460	ENOG4105CDA	abc transporter atp-binding protein
U876_07465	ENOG4105E5Q	amino acid AbC transporter
U876_07470	ENOG4106TNF	Periplasmic binding protein
U876_07475	ENOG4105BZU	Histidine kinase
U876_07480	ENOG4105CXY	transporter
U876_07485	ENOG4105BZU	Histidine kinase
U876_07490	ENOG4108KX4	response regulator
U876_07495	ENOG4105NXH	GreA GreB family elongation factor
U876_07525	ENOG4105C9W	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity (By similarity)
U876_07530	ENOG4108ISG	Major Facilitator
U876_07535	ENOG4105DGU	Histone deacetylase
U876_07545	ENOG4105DVT	helicase
U876_07550	ENOG4105QMY	Porin Gram-negative type
U876_07560	ENOG4105CGF	Aromatic amino acid aminotransferase
U876_07565	ENOG4105D7A	ATP-binding protein
U876_07715	ENOG4105CHD	Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) (By similarity)
U876_07720	ENOG4105W49	UPF0434 protein
U876_07725	ENOG4105CET	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria (By similarity)
U876_07730	ENOG4105WH1	Two component transcriptional regulator luxr family
U876_07735	ENOG4105CII	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity)
U876_07785	ENOG4105E5H	Transposase
U876_07795	ENOG4105C26	Dehydrogenase
U876_07805	ENOG4108HRG	Involved in the cleavage of the C1-C2 bond of 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy- glucuronate (5DG) (By similarity)
U876_07825	ENOG4105E9V	Periplasmic binding protein LacI transcriptional regulator
U876_07835	ENOG4105CNN	ABC, transporter
U876_07845	ENOG4105D7K	pfkb domain protein
U876_07855	ENOG4105DH8	myo-inositol catabolism
U876_07865	ENOG4108ZQS	transposase
U876_07870	ENOG4108MVM	Transposase
U876_07935	ENOG4105JJ8	Cytochrome c nitrite reductase, pentaheme subunit
U876_07940	ENOG4105D3S	4Fe-4S Ferredoxin, iron-sulfur binding domain protein
U876_07945	ENOG4105DVI	reductase, NrfD
U876_07950	ENOG4105F10	Catalyzes the hydrolysis of the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1- phosphate (lipid X) and UMP (By similarity)
U876_07960	ENOG4108R5K	PPIases accelerate the folding of proteins (By similarity)
U876_07985	ENOG410620I	Diguanylate cyclase
U876_08020	ENOG4108ZJT	translation initiation factor, Sui1
U876_08045	ENOG4107QQ4	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans (By similarity)
U876_08050	ENOG4105CZX	twitching motility protein
U876_08060	ENOG4105BZU	Histidine kinase
U876_08065	ENOG4108ESU	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Involved in the translocation of the substrate across the membrane (By similarity)
U876_08070	ENOG41080WI	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system (By similarity)
U876_08080	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
U876_08085	ENOG41080IJ	Diacylglycerol kinase
U876_08090	ENOG4108JQ1	Dehydrogenase
U876_08095	ENOG4105E66	phosphoriboisomerase A
U876_08100	ENOG4105E66	phosphoriboisomerase A
U876_08105	ENOG4105MK2	5-formyltetrahydrofolate cyclo-ligase
U876_08115	ENOG4105DUK	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity)
U876_08120	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
U876_08125	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
U876_08130	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
U876_08135	ENOG4107QS8	(LipO)protein
U876_08160	ENOG4108MK9	spermidine N(1)-acetyltransferase
U876_08165	ENOG4105C1J	atp-dependent rna helicase
U876_08190	ENOG4108Z4X	TRANSCRIPTIONal
U876_08205	ENOG4105EAB	amino acid AbC transporter
U876_08210	ENOG4105DRP	amino acid AbC transporter
U876_08215	ENOG4105CDA	abc transporter atp-binding protein
U876_08220	ENOG4105BZ8	glutamate synthase
U876_08225	ENOG4105CBC	glutamate synthase
U876_08230	ENOG4105N5T	Radical SAM Protein
U876_08240	ENOG4105C42	Type I secretion membrane fusion protein (HlyD
U876_08280	ENOG4105C85	amino acid
U876_08290	ENOG4105CF9	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation (By similarity)
U876_08295	ENOG4108HRN	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate (By similarity)
U876_08350	ENOG4105D01	(LipO)protein
U876_08355	ENOG4105EYK	Phosphatidylglycerophosphatase B
U876_08360	ENOG4105CJ0	Catalyzes the oxidation of erythronate-4-phosphate to 3- hydroxy-2-oxo-4-phosphonooxybutanoate (By similarity)
U876_08365	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
U876_08375	ENOG4105DI7	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity)
U876_08380	ENOG4107QTG	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA (By similarity)
U876_08385	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
U876_08390	ENOG4108S3P	Sporulation domain protein
U876_08395	ENOG4108Z0T	Part of a sulfur-relay system (By similarity)
U876_08400	ENOG4105EM2	membrane
U876_08405	ENOG4108MN8	Membrane
U876_08425	ENOG4105DIJ	Phosphoethanolamine transferase
U876_08435	ENOG4105FF5	Membrane
U876_08445	ENOG4107RHT	methyl-accepting chemotaxis sensory transducer with Pas Pac sensor
U876_08450	ENOG4105BZU	Histidine kinase
U876_08455	ENOG4108W1A	pseudouridine synthase
U876_08465	ENOG4105E6K	4-Hydroxyphenylpyruvate dioxygenase
U876_08470	ENOG4105F1J	Homogentisate 1,2-dioxygenase
U876_08480	ENOG4108RXX	maleylacetoacetate isomerase
U876_08485	ENOG4108TGY	Glutathione S-transferase
U876_08495	ENOG4105CAQ	asparagine synthetase
U876_08505	ENOG4105CKD	glutathione-regulated potassium-efflux system protein
U876_08510	ENOG4105D4U	had-superfamily hydrolase, subfamily iia
U876_08515	ENOG4105EKD	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism (By similarity)
U876_08520	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
U876_08525	ENOG4105EE5	Membrane protein terC
U876_08535	ENOG4105CQB	FAD linked oxidase domain protein
U876_08545	ENOG4105KA0	thioesterase Superfamily protein
U876_08555	ENOG4105D3Y	Na H antiporter
U876_08560	ENOG4105DH5	Responsible for the end-turnover of tRNA specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis (By similarity)
U876_08570	ENOG4105EIY	sodium-type flagellar protein motY
U876_08575	ENOG4108UYE	Lactoylglutathione lyase
U876_08580	ENOG4105CSM	endonuclease III
U876_08585	ENOG4105DZB	Electron transport complex
U876_08595	ENOG4105D6A	Electron transport complex
U876_08605	ENOG4108R3D	Electron transport complex
U876_08610	ENOG4105DGN	Electron transport complex
U876_08615	ENOG4108PCN	EamA-like transporter family
U876_08625	ENOG4107SDU	Methyl-accepting chemotaxis
U876_08630	ENOG4105RKW	reductase (By
U876_08635	ENOG4105CSX	c4-dicarboxylate anaerobic carrier
U876_08640	ENOG4105CHM	Aminotransferase
U876_08650	ENOG41090BQ	Glutaredoxin
U876_08655	ENOG4106HRJ	d-alanyl-d-alanine carboxypeptidase
U876_08660	ENOG4105CFI	type iii restriction protein res subunit
U876_08665	ENOG4105EFX	secretion protein, HlyD family
U876_08680	ENOG4108NEV	two component transcriptional regulator, LytTR family
U876_08685	ENOG4108HRK	Histidine kinase
U876_08690	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
U876_08695	ENOG4108EKI	Dehydrogenase
U876_08705	ENOG4105EZI	multiple antibiotic resistance (MarC)-related protein
U876_08710	ENOG4107QSI	ABC, transporter
U876_08715	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
U876_08720	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
U876_08725	ENOG4105C3U	ABC transporter
U876_08735	ENOG4108JQ7	(ABC) transporter
U876_08740	ENOG4105DU1	integral membrane protein, terc
U876_08745	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
U876_08755	ENOG4105CK2	sodium dicarboxylate symporter
U876_08770	ENOG4105CD3	dihydroorotase
U876_08775	ENOG4107R08	Integrase
U876_08820	ENOG4105DH7	May be involved in recombination (By similarity)
U876_08855	ENOG41076J9	exonuclease VIII
U876_08960	ENOG4105NY2	NinB protein
U876_08990	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
U876_08995	ENOG4105KT5	UmuD protein
U876_09180	ENOG4108NVR	Methyl-accepting chemotaxis
U876_09185	ENOG4105K59	histidine triad (HIT) protein
U876_09220	ENOG4107QN8	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
U876_09225	ENOG4107RAB	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
U876_09235	ENOG4105CKW	Inner membrane protein yedI
U876_09240	ENOG4105DPN	Oligoendopeptidase f
U876_09245	ENOG4105DPN	Oligoendopeptidase f
U876_09250	ENOG4105C2W	permease
U876_09260	ENOG4105CEP	NADH dehydrogenase
U876_09280	ENOG4105K8R	UPF0145 protein
U876_09290	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
U876_09295	ENOG410810Y	Sulfite reductase
U876_09300	ENOG4107SHJ	sulfite reductase subunit b
U876_09305	ENOG4105D5B	Sulfite reductase, subunit A
U876_09310	ENOG4108NRW	Phospholipase, patatin family
U876_09315	ENOG4105EBE	Peptidase U61, LD-carboxypeptidase A
U876_09320	ENOG4107T7U	Sulfatase
U876_09330	ENOG4105CFH	Aspartokinase
U876_09335	ENOG4107QZM	n-acetylglutamate synthase
U876_09340	ENOG4107QXP	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
U876_09365	ENOG4105F2Z	3-oxoadipate enol-lactonase
U876_09380	ENOG4105CR8	Transcriptional regulator
U876_09385	ENOG4105DAA	L-lactate
U876_09395	ENOG4107QR9	Iron-sulfur cluster binding protein
U876_09400	ENOG4108ZZK	Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source (By similarity)
U876_09420	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
U876_09430	ENOG4105C2C	drug resistance transporter, Bcr CflA
U876_09480	ENOG4105CHH	sulfate transporter
U876_09545	ENOG4108ZQS	transposase
U876_09565	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
U876_09570	ENOG4105C8Q	Methyl-accepting chemotaxis
U876_09575	ENOG4105BZU	Histidine kinase
U876_09580	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
U876_09585	ENOG4105BZU	Histidine kinase
U876_09590	ENOG4108V3W	Chemotaxis protein, CheW
U876_09595	ENOG4105C8Q	Methyl-accepting chemotaxis
U876_09600	ENOG4105CBS	Chea signal transduction histidine kinase
U876_09610	ENOG4108VYJ	response regulator receiver protein
U876_09615	ENOG4105E3S	small subunit
U876_09620	ENOG4105QA4	4Fe-4S Ferredoxin, iron-sulfur binding domain protein
U876_09625	ENOG4105CJ5	hydrogenase 2 b cytochrome subunit
U876_09630	ENOG4105DPX	Hydrogenase, large subunit
U876_09635	ENOG4108USZ	hydrogenase
U876_09640	ENOG4108WGS	hydrogenase 2-specific chaperone
U876_09645	ENOG4107RNA	Nickel ABC transporter, periplasmic nickel-binding protein
U876_09650	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
U876_09655	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
U876_09660	ENOG4105C3U	ABC transporter
U876_09665	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
U876_09670	ENOG4107RSS	Hydrogenase accessory protein HypB
U876_09675	ENOG4105WMM	Probably plays a role in a hydrogenase nickel cofactor insertion step (By similarity)
U876_09680	ENOG4105C45	hydrogenase expression formation protein (HypE)
U876_09685	ENOG4105CQS	hydrogenase expression formation protein HypD
U876_09690	ENOG4105WRB	Hydrogenase assembly chaperone hypC hupF
U876_09700	ENOG4105EM7	Selenocysteine-specific translation elongation factor
U876_09705	ENOG4105C1Y	Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis (By similarity)
U876_09715	ENOG4108MG9	hydrogenase 3 maturation protease
U876_09720	ENOG4105I6X	formate hydrogenlyase maturation
U876_09725	ENOG4105C47	NADH ubiquinone oxidoreductase 20 kda subunit
U876_09735	ENOG4105CQV	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
U876_09740	ENOG4107TDF	Formate hydrogenlyase subunit 4
U876_09745	ENOG4108JPZ	Monovalent cation H antiporter subunit D
U876_09750	ENOG4108MFN	small subunit of hydrogenase-3, iron-sulfur protein (part of formate hydrogenlyase (FHL) complex)
U876_09755	ENOG4105DFH	Transport of potassium into the cell (By similarity)
U876_09765	ENOG4108RC0	Electron transport protein
U876_09770	ENOG4107QIW	Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity)
U876_09775	ENOG4107QIW	Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity)
U876_09785	ENOG4108JUA	Transcriptional regulator
U876_09790	ENOG4107H9G	Necessary for formate dehydrogenase activity (By similarity)
U876_09795	ENOG4105F3K	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity)
U876_09800	ENOG4105CJX	Molecular chaperone. Has ATPase activity (By similarity)
U876_09805	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
U876_09810	ENOG4105CFX	Catalyzes the ferrous insertion into protoporphyrin IX (By similarity)
U876_09820	ENOG4107RE1	Inosine-guanosine kinase
U876_09835	ENOG4105BZU	Histidine kinase
U876_09840	ENOG4107QQ4	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans (By similarity)
U876_09850	ENOG4105F3T	(LipO)protein
U876_09860	ENOG4108IQC	2,3-dihydroxybenzoate-AMP ligase
U876_09865	ENOG4105WQI	isochorismatase
U876_09870	ENOG4105CEY	Amp-dependent synthetase and ligase
U876_09875	ENOG4105X17	23-dihydro-2,3-dihydroxybenzoate dehydrogenase
U876_09885	ENOG4105CEY	Amp-dependent synthetase and ligase
U876_09890	ENOG4108MES	Periplasmic binding protein
U876_09895	ENOG4108TSE	Transferase
U876_09900	ENOG4105E0A	ABC, transporter
U876_09905	ENOG4105TVJ	transport system, permease
U876_09910	ENOG4105DQ5	transport system permease protein
U876_09915	ENOG4105D05	Receptor
U876_09930	ENOG4105QZU	Inner membrane protein YfeZ
U876_09935	ENOG4107QUT	magnesium and cobalt transport protein CorA
U876_09940	ENOG4105DWH	electron transfer flavoprotein-ubiquinone oxidoreductase
U876_09945	ENOG4105BZJ	Electron transfer flavoprotein
U876_09955	ENOG4105C10	Electron transfer flavoprotein
U876_09960	ENOG4107QM1	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine (By similarity)
U876_09965	ENOG4105CMY	5-enolpyruvylshikimate-3-phosphate synthase
U876_09970	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
U876_09975	ENOG4108NVR	Methyl-accepting chemotaxis
U876_09980	ENOG4105D4P	Coproporphyrinogen iii oxidase
U876_09985	ENOG4105DVS	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
U876_10010	ENOG4105DFH	Transport of potassium into the cell (By similarity)
U876_10015	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
U876_10020	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
U876_10025	ENOG4105DFP	Integrase
U876_10090	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
U876_10105	ENOG4105FQ6	thiopurine methyltransferase
U876_10110	ENOG4107VK2	coenzyme PQQ biosynthesis protein PqqF
U876_10115	ENOG4108BY2	phosphohistidine phosphatase
U876_10125	ENOG4108IPJ	Membrane
U876_10130	ENOG4108J59	Extracellular solute-binding protein, family 5
U876_10135	ENOG4105CZI	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
U876_10140	ENOG4108JA2	transcriptioN-repair coupling factor
U876_10150	ENOG4105D60	lipoprotein releasing system transmembrane protein
U876_10155	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
U876_10160	ENOG4105D60	lipoprotein releasing system transmembrane protein
U876_10175	ENOG4105DEA	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation
U876_10180	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
U876_10185	ENOG4105CHN	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
U876_10190	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
U876_10195	ENOG4105K70	DNA-binding protein
U876_10200	ENOG4105EIN	peptidylprolyl cis-trans isomerase
U876_10205	ENOG4105C5H	ABC transporter
U876_10210	ENOG4107QN1	sodium solute
U876_10215	ENOG41062QD	Membrane
U876_10230	ENOG41060WC	Enoyl-CoA hydratase
U876_10275	ENOG4105BZG	amino acid carrier protein
U876_10290	ENOG4106HK8	GPR1 FUN34 yaaH family protein
U876_10330	ENOG4107QX3	carboxylase
U876_10335	ENOG4105C1G	acyl-Coa dehydrogenase
U876_10340	ENOG4105C26	Dehydrogenase
U876_10345	ENOG4105C1G	acyl-Coa dehydrogenase
U876_10350	ENOG4105E39	Enoyl-CoA hydratase
U876_10355	ENOG4105E39	Enoyl-CoA hydratase
U876_10360	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
U876_10365	ENOG4105CHR	reductase
U876_10370	ENOG4105D5Q	Arginine ornithine antiporter
U876_10375	ENOG4105HF0	Membrane
U876_10390	ENOG4108J1Q	
U876_10400	ENOG4105BZU	Histidine kinase
U876_10425	ENOG4105W5Q	DNA repair protein (RadC
U876_10455	ENOG4105EQ2	LysR family Transcriptional regulator
U876_10460	ENOG4105ENX	hydrolase
U876_10465	ENOG4105DRY	peptidase s9 prolyl oligopeptidase active site domain protein
U876_10475	ENOG4105HEI	LysR family (Transcriptional regulator
U876_10480	ENOG4105CPC	Aldo Keto reductase
U876_10495	ENOG4105BZU	Histidine kinase
U876_10500	ENOG4108KB2	LysR family Transcriptional regulator
U876_10505	ENOG4105CS2	ec 3.2.1.21
U876_10510	ENOG4105BZU	Histidine kinase
U876_10525	ENOG4105DHT	Metal Dependent Phosphohydrolase
U876_10530	ENOG4105CHR	reductase
U876_10535	ENOG4105CBN	LysR family transcriptional regulator
U876_10540	ENOG4105EFU	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin (By similarity)
U876_10550	ENOG4105DUM	transcriptional regulator, lysR family
U876_10560	ENOG4105NWR	lipid A biosynthesis (Kdo)2-(Lauroyl)-lipid IVA acyltransferase
U876_10565	ENOG4105NWR	lipid A biosynthesis (Kdo)2-(Lauroyl)-lipid IVA acyltransferase
U876_10590	ENOG4105CQ2	DNA polymerase
U876_10620	ENOG4107QI1	Mate efflux family protein
U876_10625	ENOG4105W1I	UPF0253 protein
U876_10630	ENOG4108R6K	riboflavin synthase, subunit alpha
U876_10640	ENOG4107UW8	HAD-superfamily hydrolase subfamily IA variant 3
U876_10645	ENOG4108HH9	Catalyzes two reactions the first one is the production of beta-formyl glycinamide ribonucleotide (GAR) from formate, ATP and beta GAR
U876_10650	ENOG4108SXK	Transporter Drug Metabolite Exporter family
U876_10655	ENOG4108V3G	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity)
U876_10690	ENOG4105XW2	UPF0263 protein
U876_10695	ENOG4108VKV	Monofunctional biosynthetic peptidoglycan transglycosylase
U876_10705	ENOG4105VJP	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell (By similarity)
U876_10710	ENOG4107QMS	site-determining protein
U876_10715	ENOG4105K7U	Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization (By similarity)
U876_10720	ENOG4105VNG	YcgL domain-containing protein
U876_10725	ENOG4105CVE	Lytic murein transglycosylase
U876_10730	ENOG4105EJQ	L-serine dehydratase
U876_10735	ENOG4105EJQ	L-serine dehydratase
U876_10740	ENOG4105NBK	UPF0345 protein
U876_10745	ENOG4105CK2	sodium dicarboxylate symporter
U876_10755	ENOG4105CHU	acetyl-coa acetyltransferase
U876_10760	ENOG4105D58	Diguanylate phosphodiesterase
U876_10765	ENOG4105CKF	membrane protein involved in aromatic hydrocarbon degradation
U876_10770	ENOG4105CKF	membrane protein involved in aromatic hydrocarbon degradation
U876_10780	ENOG4105EMN	RNA polymerase sigma factor
U876_10810	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
U876_10815	ENOG4105CHU	acetyl-coa acetyltransferase
U876_10820	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
U876_10830	ENOG4108VWS	Yaeq family
U876_10840	ENOG4105QIB	mu-like prophage Flumu protein gp29
U876_10855	ENOG4108TVE	i protein
U876_10860	ENOG4108JUB	Transcriptional regulator
U876_10865	ENOG4105IW6	Carbamoyltransferase
U876_10870	ENOG4107RCH	Diaminopropionate ammonia-lyase
U876_10875	ENOG4107S4Y	M20 DapE family protein YgeY
U876_10885	ENOG4105C5B	carbamate kinase
U876_10895	ENOG4108Q5Y	Membrane
U876_10900	ENOG4107P0T	Selenium-dependent molybdenum hydroxylase system protein, YqeB family
U876_10905	ENOG4105MJ6	selenium-dependent hydroxylase accessory protein YqeC
U876_10910	ENOG4105MFX	4-diphosphocytidyl-2c-methyl-d-erythritol synthase
U876_10920	ENOG4105BZ8	glutamate synthase
U876_10925	ENOG4107UUR	Chlorohydrolase aminohydrolase
U876_10930	ENOG410873Y	FAD binding domain in molybdopterin dehydrogenase
U876_10935	ENOG4105C7W	Xanthine dehydrogenase
U876_10940	ENOG4105C2W	permease
U876_10945	ENOG4107QUY	Guanine deaminase
U876_10950	ENOG4105C7N	Xanthine uracil vitamin C permease
U876_10955	ENOG4105C7W	Xanthine dehydrogenase
U876_10960	ENOG4108HR6	Dehydrogenase
U876_10965	ENOG4108UTP	(2Fe-2S)-binding domain protein
U876_10975	ENOG4107MBR	17 kDa surface antigen
U876_10985	ENOG4105CSX	c4-dicarboxylate anaerobic carrier
U876_10990	ENOG4105CEY	Amp-dependent synthetase and ligase
U876_10995	ENOG4105K8F	Phosphoribosyl-amp cyclohydrolase
U876_11000	ENOG4105C0S	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity)
U876_11005	ENOG4105BZU	Histidine kinase
U876_11015	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
U876_11020	ENOG4105CJV	Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase
U876_11025	ENOG4108UJE	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity)
U876_11035	ENOG4105CIH	Imidazole acetol-phosphate transaminase
U876_11040	ENOG4105CEK	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity)
U876_11045	ENOG4105E21	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity)
U876_11055	ENOG4105DVT	helicase
U876_11060	ENOG41072GX	Peptidase M22 Glycoprotease
U876_11070	ENOG410626R	Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity)
U876_11075	ENOG4105CEY	Amp-dependent synthetase and ligase
U876_11080	ENOG4105ZIE	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides (By similarity)
U876_11085	ENOG4106PMH	Extracellular solute-binding protein family 3
U876_11215	ENOG4107TII	Recombinase
U876_11225	ENOG4105FBT	Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs (By similarity)
U876_11230	ENOG4105WD1	Membrane
U876_11235	ENOG4109003	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity)
U876_11240	ENOG4107QMP	dna polymerase iii subunits gamma and tau
U876_11245	ENOG4105KDX	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection (By similarity)
U876_11250	ENOG4107R08	Integrase
U876_11280	ENOG41076J9	exonuclease VIII
U876_11385	ENOG4105CH6	catalase
U876_11410	ENOG4108ZUE	Phage regulatory protein rha
U876_11415	ENOG4105NY2	NinB protein
U876_11435	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
U876_11440	ENOG4105KT5	UmuD protein
U876_11625	ENOG4105CQ7	ATP-dependent helicase
U876_11640	ENOG4105BZU	Histidine kinase
U876_11645	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
U876_11650	ENOG4105C5X	domain protein
U876_11655	ENOG4105CR7	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA (By similarity)
U876_11660	ENOG4105D4F	Synthesizes selenophosphate from selenide and ATP (By similarity)
U876_11675	ENOG4105FAT	Acyl-transferase
U876_11685	ENOG4105DR4	Methyltransferase
U876_11690	ENOG4108N3W	hemolysin secretion protein
U876_11695	ENOG4105VSY	K01512 acylphosphatase EC 3.6.1.7
U876_11700	ENOG4108K3A	Glutathione S-transferase
U876_11705	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
U876_11710	ENOG4105D1F	ATP-binding protein
U876_11715	ENOG4105DBI	uridine monophosphokinase
U876_11720	ENOG4105DHP	deoxycytidine triphosphate deaminase
U876_11730	ENOG4105CJ3	phosphate transporter
U876_11735	ENOG4105C03	ribonuclease
U876_11740	ENOG4105EI2	Pseudouridine synthase
U876_11750	ENOG4108UHJ	MAF-like protein
U876_11755	ENOG4105CNH	Multidrug resistance protein MdtL
U876_11770	ENOG4105FCQ	metal-binding, possibly nucleic acid-binding protein
U876_11775	ENOG4105VGS	50s ribosomal protein l32
U876_11780	ENOG4105C6B	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA (By similarity)
U876_11785	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
U876_11790	ENOG4105CJF	Malonyl coA-acyl carrier protein transacylase
U876_11795	ENOG4105CHR	reductase
U876_11800	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
U876_11805	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
U876_11810	ENOG4105YAZ	4-amino-4-deoxychorismate lyase
U876_11815	ENOG4105HHA	aminodeoxychorismate lyase
U876_11820	ENOG4108ZMD	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity)
U876_11825	ENOG4107QRG	dna polymerase iii
U876_11830	ENOG4105F8V	Hydrolase, tatD family
U876_11845	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
U876_11850	ENOG4105DY2	Paraquat-inducible protein b
U876_11855	ENOG4105F1S	paraquat-inducible protein a
U876_11865	ENOG4105CR4	methylisocitrate lyase
U876_11870	ENOG4105BZN	citrate synthase
U876_11875	ENOG4105DXD	2-methylcitrate dehydratase
U876_11915	ENOG4105PDP	Short chain dehydrogenase
U876_11925	ENOG4105X2V	dna damage-inducible protein
U876_11935	ENOG4105DAN	ATP-dependent protease
U876_11940	ENOG4108RKI	Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl- ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)- decenoyl-ACP. Can catalyze the dehydratase reaction for beta- hydroxyacyl-ACPs with saturated chain lengths up to 16 0, being most active on intermediate chain length (By similarity)
U876_11945	ENOG4105WFT	During stationary phase, converts 70S ribosomes to an inactive dimeric form (100S ribosomes) (By similarity)
U876_11955	ENOG4105C5H	ABC transporter
U876_11965	ENOG4105C4H	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA (By similarity)
U876_11970	ENOG4108T7E	Contributes to the efficiency of the cell division process by stabilizing the polymeric form of the cell division protein FtsZ. Acts by promoting interactions between FtsZ protofilaments and suppressing the GTPase activity of FtsZ (By similarity)
U876_11975	ENOG4107QYT	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor (By similarity)
U876_11980	ENOG4105C7I	Dehydrogenase
U876_11990	ENOG4105CD8	aminopeptidase N
U876_11995	ENOG4105CN1	protease
U876_12000	ENOG41073DY	may be a structural element that influences the osmotic activation of ProP at a post-translational level (By similarity)
U876_12005	ENOG4108ZGC	gaf domain protein
U876_12015	ENOG4105EUH	cytochrome C oxidase, cbb3-type, subunit i
U876_12030	ENOG4105D6P	C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex (By similarity)
U876_12055	ENOG4105DS0	Transcriptional regulator, Crp Fnr family
U876_12060	ENOG4105Q9Y	Universal stress protein
U876_12065	ENOG4105CB3	Required for the thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32) (By similarity)
U876_12080	ENOG4108RXX	maleylacetoacetate isomerase
U876_12085	ENOG4105MRB	Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose (By similarity)
U876_12090	ENOG4105C2J	ABC transporter
U876_12095	ENOG4105CNN	ABC, transporter
U876_12100	ENOG4105E9V	Periplasmic binding protein LacI transcriptional regulator
U876_12105	ENOG4108RVA	ribokinase
U876_12110	ENOG4105ETE	Transcriptional regulator (LacI family
U876_12125	ENOG4105NDF	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity)
U876_12140	ENOG4105BZU	Histidine kinase
U876_12145	ENOG4108ZUF	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
U876_12150	ENOG4105C6A	phenylalanyl-tRNA synthetase (beta subunit)
U876_12155	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
U876_12160	ENOG4108YZX	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity)
U876_12165	ENOG41083UC	50s ribosomal protein L35
U876_12170	ENOG4108UUX	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity)
U876_12175	ENOG4105C22	threonyL-tRNA synthetase
U876_12195	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
U876_12200	ENOG4108HWB	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
U876_12205	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
U876_12210	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
U876_12215	ENOG4105E05	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
U876_12220	ENOG4105XPH	Ferredoxin
U876_12225	ENOG4105CA3	membrane-bound lytic murein transglycosylase
U876_12230	ENOG4105XZD	Fe-S protein
U876_12235	ENOG4107SZR	mannose-6-phosphate isomerase
U876_12240	ENOG4105F3R	pts system mannose fructose sorbose family iid
U876_12245	ENOG4105ETZ	PTS System
U876_12250	ENOG4108EQA	pts system
U876_12265	ENOG4107P2S	Transcriptional regulator
U876_12270	ENOG4108Y83	glucose-6-phosphate isomerase
U876_12275	ENOG4105DM4	PTS System
U876_12280	ENOG4105DE4	1-phosphofructokinase
U876_12285	ENOG4105DTZ	bifunctional PTS system fructose-specific transporter subunit IIA HPr protein
U876_12290	ENOG4107B7Y	DNA-binding transcriptional regulator FruR
U876_12295	ENOG4105E0U	tyrosine-specific transport protein
U876_12310	ENOG4105C1J	atp-dependent rna helicase
U876_12320	ENOG4105D10	5-enolpyruvylshikimate-3-phosphate phospholyase
U876_12325	ENOG4105C76	Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue (By similarity)
U876_12330	ENOG4108DG9	Smr protein MutS2
U876_12340	ENOG4105BZU	Histidine kinase
U876_12345	ENOG4105DKJ	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
U876_12375	ENOG4108Z8G	Alkylphosphonate utilization operon protein PhnA
U876_12410	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
U876_12430	ENOG4105DUC	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division (By similarity)
U876_12435	ENOG4105DAH	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF (By similarity)
U876_12445	ENOG4106371	Methyltransferase
U876_12450	ENOG4107S90	membrAne
U876_12460	ENOG4105CTQ	phosphohexokinase
U876_12465	ENOG4105CH2	amidohydrolase
U876_12470	ENOG4105PAD	Hydrolase
U876_12475	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
U876_12510	ENOG4105CPB	ATP-dependent endonuclease of the OLD family
U876_12525	ENOG4105VP0	transcriptional regulator, lysR family
U876_12530	ENOG4105EJ9	Membrane
U876_12540	ENOG4106IUH	DTW domain containing protein
U876_12550	ENOG4105CPF	Cell wall formation (By similarity)
U876_12560	ENOG4108V06	Glutathione peroxidase
U876_12565	ENOG4105C1J	atp-dependent rna helicase
U876_12570	ENOG4105K5X	acetyltransferase
U876_12580	ENOG4105KK4	UPF0060 membrane protein
U876_12610	ENOG41061CK	Antibiotic biosynthesis monooxygenase
U876_12615	ENOG4107XGF	functions in a salvage pathway. Uses pyridoxamine (By similarity)
U876_12645	ENOG4105D1N	poly(r)-hydroxyalkanoic acid synthase, class
U876_12655	ENOG4105WQ3	Rna-binding protein
U876_12670	ENOG4105BZ1	(ABC) transporter
U876_12680	ENOG4105BZ1	(ABC) transporter
U876_12685	ENOG4105BZU	Histidine kinase
U876_12690	ENOG4105K63	Thioredoxin
U876_12695	ENOG4105C8P	)-transporter
U876_12700	ENOG4107QQN	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties (By similarity)
U876_12735	ENOG4105C44	Serine transporter
U876_12740	ENOG4107QV7	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system) (By similarity)
U876_12745	ENOG4105C9U	ATP-dependent DNA helicase RecQ
U876_12750	ENOG4105CYN	Serine protein kinase
U876_12760	ENOG4105ED1	spovr family
U876_12765	ENOG4105C05	Multifunctional regulator of fatty acid metabolism (By similarity)
U876_12770	ENOG4105DKR	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity)
U876_12775	ENOG410635M	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein (By similarity)
U876_12780	ENOG4105DQR	SNARE associated Golgi
U876_12790	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
U876_12800	ENOG4105D0C	transport protein
U876_12805	ENOG4105CHQ	Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella (By similarity)
U876_12825	ENOG4108MRH	transcriptional regulatory protein
U876_12830	ENOG4105CEQ	signal transduction histidine kinase regulating citrate malate metabolism
U876_12835	ENOG4105E2R	ROK family
U876_12840	ENOG4105C8Q	Methyl-accepting chemotaxis
U876_12845	ENOG4105K5B	UPF0225 protein
U876_12850	ENOG4107R5Y	anaerobic glycerol-3-phosphate dehydrogenase, subunit A
U876_12855	ENOG4108KJ0	anaerobic glycerol-3-phosphate dehydrogenase, subunit B
U876_12860	ENOG4105CHG	glycolate oxidase (iron-sulfur subunit)
U876_12880	ENOG4105JJ8	Cytochrome c nitrite reductase, pentaheme subunit
U876_12885	ENOG4105D3S	4Fe-4S Ferredoxin, iron-sulfur binding domain protein
U876_12890	ENOG4105DVI	reductase, NrfD
U876_12895	ENOG4105DA4	cytochrome c-type biogenesis protein
U876_12900	ENOG4107QX9	Thiol disulfide interChange protein
U876_12910	ENOG4108Z4K	mutator MutT protein
U876_12915	ENOG41061WM	D-Alanyl-D-Alanine
U876_12920	ENOG4105C0F	tryptophanase EC 4.1.99.1
U876_12925	ENOG4105EXX	Deoxyribodipyrimidine photolyase-related protein
U876_12930	ENOG4105MWK	D-amino acid dehydrogenase, small subunit
U876_12945	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
U876_12955	ENOG4105DSS	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation (By similarity)
U876_12960	ENOG4105DZ2	Transcriptional regulator
U876_12970	ENOG4105E0K	tonB-dependent siderophore receptor
U876_12975	ENOG4108XW0	May be a transcriptional activator of genes involved in the multiple antibiotic resistance (Mar) phenotype. It can also activate genes such as sodA, zwf and micF
U876_12985	ENOG4105CR8	Transcriptional regulator
U876_12990	ENOG4108RYK	Nad-dependent epimerase dehydratase
U876_13000	ENOG4105C28	cystathionine
U876_13010	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
U876_13015	ENOG4105KPY	Small multidrug resistance protein
U876_13020	ENOG4105DDY	UPF0142 protein ycaO
U876_13025	ENOG4105TMB	Formate nitrite transporter
U876_13030	ENOG4105C6N	Formate acetyltransferase
U876_13035	ENOG4108KAZ	Involved in phosphonate degradation (By similarity)
U876_13040	ENOG4108JPW	Aminotransferase
U876_13045	ENOG4107STF	Involved in phosphonate degradation (By similarity)
U876_13055	ENOG4105C4Y	ABC transporter
U876_13065	ENOG4107RCV	ABC transporter, permease
U876_13070	ENOG4105CJP	fad dependent oxidoreductase
U876_13085	ENOG4105CH8	Succinyl-CoA ligase ADP-forming subunit alpha
U876_13090	ENOG4105CMV	Succinyl-CoA synthetase subunit beta
U876_13095	ENOG4105C7S	Dehydrogenase
U876_13100	ENOG4105C7P	2-oxoglutarate dehydrogenase, E1
U876_13105	ENOG4105E33	succinate dehydrogenase
U876_13110	ENOG4105C00	Succinate dehydrogenase (Flavoprotein subunit)
U876_13115	ENOG4105N1I	succinate dehydrogenase, hydrophobic membrane anchor protein
U876_13120	ENOG4108UTY	succinate dehydrogenase, cytochrome b556 subunit
U876_13125	ENOG4105BZN	citrate synthase
U876_13140	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
U876_13145	ENOG4105CWG	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34 (By similarity)
U876_13155	ENOG4105CEE	C4-dicarboxylate transporter
U876_13170	ENOG4108VKG	metal-dependent hydrolase
U876_13185	ENOG4105NRA	50s ribosomal protein l31 type b
U876_13195	ENOG4105EUB	pirin domain protein
U876_13200	ENOG4105HEI	LysR family (Transcriptional regulator
U876_13210	ENOG4105CNN	ABC, transporter
U876_13220	ENOG4105DMK	Periplasmic binding protein LacI transcriptional regulator
U876_13225	ENOG4105EF1	ribulokinase
U876_13235	ENOG4105CAC	Catalyzes the conversion of L-arabinose to L-ribulose (By similarity)
U876_13240	ENOG4105CJB	Exodeoxyribonuclease I
U876_13250	ENOG4107R49	K07407 alpha-galactosidase EC 3.2.1.22
U876_13260	ENOG41067MG	lrgb family
U876_13265	ENOG4107T42	This enzyme scavenge exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis (By similarity)
U876_13270	ENOG4108IQE	Amp-dependent synthetase and ligase
U876_13275	ENOG4105MH2	YfcL protein
U876_13285	ENOG4105EE5	Membrane protein terC
U876_13290	ENOG41090EK	ompa motb domain protein
U876_13295	ENOG4108KHX	Diguanylate cyclase
U876_13300	ENOG4108WS1	
U876_13310	ENOG41090A4	Pterin carbinolamine dehydratase
U876_13315	ENOG41090A4	Pterin carbinolamine dehydratase
U876_13320	ENOG4105MIR	Phenylalanine 4-monooxygenase
U876_13325	ENOG4106K28	UPF0283 membrane protein
U876_13330	ENOG4105CM6	amino acid regulated cytosolic protein
U876_13340	ENOG4105YYT	phage shock protein B
U876_13345	ENOG41087YS	Phage shock protein A
U876_13350	ENOG4105E51	psp operon transcriptional activator
U876_13355	ENOG4108J59	Extracellular solute-binding protein, family 5
U876_13360	ENOG4108I5W	peptide transport system, permease protein
U876_13365	ENOG4108EU3	peptide transport system, permease
U876_13375	ENOG4108JQ3	Peptide ABC transporter ATP-binding protein
U876_13380	ENOG4108JQ2	peptide transport system atp-binding protein
U876_13385	ENOG4105FR9	TRNA-(Ms 2 io 6 A)-hydroxylase
U876_13390	ENOG4105CBA	glutamine phosphoribosylpyrophosphate amidotransferase
U876_13395	ENOG4105E96	Colicin v production protein
U876_13400	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
U876_13405	ENOG4105D1H	recombination factor protein RarA
U876_13410	ENOG4107Y7W	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) (By similarity)
U876_13415	ENOG4105CNU	cell division protein FtsK
U876_13420	ENOG4105EW9	transcriptional regulator AsnC family
U876_13425	ENOG4105C3M	thioredoxin reductase
U876_13430	ENOG4105BZU	Histidine kinase
U876_13435	ENOG4107MBR	17 kDa surface antigen
U876_13440	ENOG4108R4Z	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine (By similarity)
U876_13445	ENOG4105DWA	May conjugate Arg from its aminoacyl-tRNA to the N- termini of proteins containing an N-terminal aspartate or glutamate
U876_13450	ENOG4105K9U	however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity)
U876_13455	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
U876_13460	ENOG4105KAE	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation (By similarity)
U876_13465	ENOG4105VEQ	Cold shock protein
U876_13470	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
U876_13495	ENOG4105NVB	glycoside hydrolase, family 19
U876_13500	ENOG4105CS6	Rhs element vgr protein
U876_13535	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
U876_13605	ENOG4105CS6	Rhs element vgr protein
U876_13610	ENOG4108WC9	type VI secretion system effector, hcp1 family
U876_13625	ENOG4108RMJ	sensory transduction regulator
U876_13635	ENOG4107104	thymidine kinase
U876_13640	ENOG4107S6Z	Na H antiporter
U876_13650	ENOG4108WBT	adenosyltransferase
U876_13655	ENOG4105VRT	cytoplasmic protein
U876_13660	ENOG4105EIZ	Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity)
U876_13665	ENOG4105FD2	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) (By similarity)
U876_13680	ENOG4106EG9	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) (By similarity)
U876_13685	ENOG4105CFV	Tetratricopeptide repeat protein
U876_13695	ENOG41080YA	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
U876_13700	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
U876_13705	ENOG4105CAT	Cytidine monophosphate kinase
U876_13710	ENOG4108JEN	Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate (By similarity)
U876_13715	ENOG4107R11	Transcriptional regulator
U876_13720	ENOG4105CMU	LysR family (Transcriptional regulator
U876_13725	ENOG4105D2S	major facilitator superfamily
U876_13740	ENOG4108DBC	nitroreductase
U876_13745	ENOG4105BZU	Histidine kinase
U876_13755	ENOG4105CBN	LysR family transcriptional regulator
U876_13760	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
U876_13785	ENOG4107RGM	aldo keto reductase
U876_13790	ENOG4105VFU	Rna-binding protein
U876_13800	ENOG4105HPZ	Involved in the removal of murein from the sacculus. May also facilitate integration of nascent murein strands into the sacculus by cleaving the peptide bonds between neighboring strands in mature murein (By similarity)
U876_13810	ENOG4105HA9	of methanol dehydrogenase type
U876_13825	ENOG4105E14	MotA TolQ exbB proton channel
U876_13830	ENOG4105ER2	Ompa motb domain protein
U876_13835	ENOG4105KWU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
U876_13840	ENOG4105ES3	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
U876_13845	ENOG4105CQV	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
U876_13850	ENOG4105GKE	subunit e
U876_13855	ENOG4107QIZ	NADH dehydrogenase
U876_13860	ENOG4108IEH	NADH dehydrogenase subunit g
U876_13865	ENOG4105CMZ	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone (By similarity)
U876_13870	ENOG4105P3U	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
U876_13875	ENOG4107UFS	subunit j
U876_13880	ENOG41080EA	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
U876_13885	ENOG4105D65	subunit l
U876_13890	ENOG4105C8S	subunit m
U876_13895	ENOG4105CNR	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
U876_13905	ENOG4107QIK	phosphoribosylformylglycinamidine synthase
U876_13910	ENOG4105CHQ	Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella (By similarity)
U876_13915	ENOG4105VPD	cellular component movement
U876_13920	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
U876_13925	ENOG4105CNE	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
U876_13930	ENOG4105N21	Membrane
U876_13935	ENOG4105CUT	histidyl-tRNA synthetase
U876_13940	ENOG4105C4E	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (By similarity)
U876_13945	ENOG4105HSZ	Cytoskeletal protein that is involved in cell-shape control through regulation of the length of the long axis (By similarity)
U876_13955	ENOG4105C55	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
U876_13960	ENOG4108UGX	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity)
U876_13965	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
U876_13975	ENOG4108ZIT	Ferredoxin, 2FE-2S
U876_13980	ENOG4105C9I	Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB
U876_13985	ENOG4108SWN	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA (By similarity)
U876_13990	ENOG4108Z4V	iron-sulfur cluster assembly
U876_13995	ENOG4107XTC	May be involved in the formation or repair of Fe-S clusters present in iron-sulfur proteins
U876_14000	ENOG4105C3J	Cysteine desulfurase
U876_14020	ENOG4105XPQ	lipid carrier protein
U876_14025	ENOG4105CFP	Peptidase U32
U876_14030	ENOG4106RZ4	Peptidase U32
U876_14045	ENOG4107RAB	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
U876_14050	ENOG4107QN8	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
U876_14055	ENOG4105VIE	preprotein translocase, subunit YajC
U876_14060	ENOG4105C6U	Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity)
U876_14065	ENOG4105E2N	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) (By similarity)
U876_14070	ENOG4105W87	Cbs domain
U876_14075	ENOG4105D3R	alkyl hydroperoxide reductase
U876_14085	ENOG4108ISG	Major Facilitator
U876_14100	ENOG4105K89	arsenate reductase
U876_14105	ENOG4105D6J	arsenicaL-resistance protein
U876_14110	ENOG41085FC	arsR family transcriptional regulator
U876_14115	ENOG4105CBI	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
U876_14120	ENOG4105KE9	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity)
U876_14125	ENOG4105D43	The glycine cleavage system catalyzes the degradation of glycine (By similarity)
U876_14130	ENOG4105EAK	ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family
U876_14135	ENOG4105D0A	hydroxylase
U876_14145	ENOG4107YUN	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division (By similarity)
U876_14150	ENOG4105E5M	Multidrug resistance protein D
U876_14155	ENOG4105CYM	Glutathione S-transferase
U876_14185	ENOG4105DUF	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively (By similarity)
U876_14200	ENOG4105C5E	polysaccharide biosynthesis protein
U876_14220	ENOG4105CDM	Glutamate-1-semialdehyde aminotransferase
U876_14255	ENOG4105MQ3	flagellar protein FliS
U876_14270	ENOG4105I03	Flagellin
U876_14285	ENOG4105I03	Flagellin
U876_14290	ENOG4105I03	Flagellin
U876_14295	ENOG4105EN6	Membrane
U876_14305	ENOG4105D8I	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS (By similarity)
U876_14315	ENOG4108JQB	penicillin-binding protein 1C
U876_14320	ENOG4105DN3	alpha-2-macroglobulin domain protein
U876_14325	ENOG4105CH2	amidohydrolase
U876_14330	ENOG4105IPI	Membrane
U876_14335	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
U876_14340	ENOG4105J12	Multidrug resistance protein mdtN
U876_14355	ENOG4107QMW	pyridine nucleotide-disulfide oxidoreductase
U876_14360	ENOG4105BZU	Histidine kinase
U876_14365	ENOG4105F1A	Pyruvate formate-lyase
U876_14380	ENOG4105DSP	amino acid AbC transporter
U876_14385	ENOG4106PMH	Extracellular solute-binding protein family 3
U876_14390	ENOG4108JEH	abc transporter atp-binding protein
U876_14395	ENOG4105DWU	Membrane
U876_14400	ENOG4105DYB	Isoaspartyl dipeptidase
U876_14405	ENOG4108ZYK	Acyl carrier protein phosphodiesterase
U876_14425	ENOG4105K89	arsenate reductase
U876_14435	ENOG4105ERG	peptidase m48, ste24p
U876_14460	ENOG4105CSR	polyphosphate kinase 2
U876_14465	ENOG4108IJ9	(ABC) transporter
U876_14470	ENOG4105EG2	ABC transporter, permease
U876_14475	ENOG4105D56	permease protein
U876_14480	ENOG4107FKK	extracellular solute-binding protein family 1
U876_14485	ENOG4106V8H	Nucleoid-associated protein
U876_14490	ENOG4105PAN	UPF0352 protein
U876_14495	ENOG4105E68	Sulfatase
U876_14500	ENOG4105D05	Receptor
U876_14505	ENOG4105CUG	Oligopeptidase b
U876_14525	ENOG4108QSZ	General inhibitor of pancreatic serine proteases inhibits chymotrypsin, trypsin, elastases, factor X, kallikrein as well as a variety of other proteases (By similarity)
U876_14530	ENOG4108WFC	UPF0438 protein yifE
U876_14535	ENOG4105CVI	Transcriptional regulator
U876_14545	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
U876_14550	ENOG4106MZZ	glycerophosphoryl diester phosphodiesterase
U876_14555	ENOG4105C6V	Glycerol-3-phosphate dehydrogenase
U876_14560	ENOG4105E98	transcriptional regulator DeoR family
U876_14565	ENOG4105CXY	transporter
U876_14570	ENOG4105D8C	Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity)
U876_14575	ENOG4108JQ0	Key enzyme in the regulation of glycerol uptake and metabolism (By similarity)
U876_14580	ENOG4105HEI	LysR family (Transcriptional regulator
U876_14600	ENOG4105CV8	reductase
U876_14605	ENOG4105F27	Major Facilitator
U876_14615	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
U876_14620	ENOG4105C4M	(Ubiquinol oxidase) subunit I
U876_14625	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
U876_14635	ENOG4108Q2J	Inner membrane protein YebE
U876_14660	ENOG4105D2S	major facilitator superfamily
U876_14675	ENOG4105DJ2	Major Facilitator Superfamily
U876_14680	ENOG4105FE9	pseudouridine synthase
U876_14690	ENOG4105D82	Glutamate dehydrogenase
U876_14710	ENOG4105CFI	type iii restriction protein res subunit
U876_14720	ENOG4105WWK	YheO domain protein
U876_14725	ENOG4105CEM	UPF0597 protein
U876_14730	ENOG4105KME	endoribonuclease L-psp
U876_14735	ENOG4105C44	Serine transporter
U876_14740	ENOG4108NVR	Methyl-accepting chemotaxis
U876_14755	ENOG4105DP5	Catalyzes the biosynthesis of agmatine from arginine (By similarity)
U876_14760	ENOG4105D42	Cleaves the N-terminal amino acid of tripeptides (By similarity)
U876_14785	ENOG4108YYC	ycei family
U876_14790	ENOG4105CC0	LysR family Transcriptional regulator
U876_14800	ENOG4105CKU	formyltetrahydrofolate synthetase
U876_14805	ENOG4105C8Q	Methyl-accepting chemotaxis
U876_14810	ENOG4105EUJ	GTP cyclohydrolase i
U876_14815	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
U876_14820	ENOG4105D06	uba thif-type nad fad binding protein
U876_14825	ENOG4105D3C	The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters (By similarity)
U876_14830	ENOG4105CGB	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system (By similarity)
U876_14835	ENOG4105E0C	molybdate abc transporter
U876_14840	ENOG4108S6J	ABC transporter, periplasmic molybdate-binding protein
U876_14845	ENOG4108ZAF	Molybdopterin
U876_14850	ENOG4105M00	molybdopterin converting factor, subunit 1
U876_14855	ENOG4108YXW	Together with MoaA, is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
U876_14860	ENOG4108RIR	Molybdenum cofactor biosynthesis protein
U876_14865	ENOG4105CUW	cytochrome C-TYPE protein
U876_14875	ENOG4105GXZ	Ferredoxin-type protein NapH
U876_14880	ENOG4108BGM	Quinol dehydrogenase periplasmic component
U876_14885	ENOG4107QIW	Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity)
U876_14900	ENOG4108ZNS	ferredoxin-type protein NapF
U876_14905	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
U876_14910	ENOG4105BZU	Histidine kinase
U876_14915	ENOG4105WH1	Two component transcriptional regulator luxr family
U876_14925	ENOG4105BZU	Histidine kinase
U876_14935	ENOG4105CHW	UPF0052 protein
U876_14945	ENOG4105E7A	Glutamine amidotransferase
U876_14950	ENOG4105F55	Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate (By similarity)
U876_14960	ENOG4107QPN	acyl-Coa dehydrogenase
U876_14970	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
U876_14980	ENOG4108JDX	DNA polymerase iii, epsilon subunit
U876_14985	ENOG4108UMW	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
U876_14990	ENOG4105D1A	Methyltransferase
U876_14995	ENOG4108RW0	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
U876_15000	ENOG4105E9H	Lytic Murein transglycosylase
U876_15015	ENOG4105NAU	thioesterase Superfamily protein
U876_15025	ENOG41060NJ	transcriptional regulator
U876_15030	ENOG4107SC1	transglycosylase
U876_15035	ENOG4105BZU	Histidine kinase
U876_15040	ENOG4108WPH	sigma 54 modulation protein ribosomal protein S30EA
U876_15065	ENOG4105CFU	surface antigen
U876_15075	ENOG4105KQ5	peptidylprolyl cis-trans isomerase
U876_15090	ENOG4107ZN8	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity (By similarity)
U876_15100	ENOG4105VNH	ABC transporter solute-binding protein
U876_15110	ENOG4108VGW	abc transporter atp-binding protein
U876_15115	ENOG4108T9J	Cdp-alcohol phosphatidyltransferase
U876_15120	ENOG4105CVE	Lytic murein transglycosylase
U876_15135	ENOG4107QIX	Phosphoglucomutase (EC 5.4.2.2
U876_15140	ENOG4107CDU	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated (By similarity)
U876_15145	ENOG4105EV9	Alpha Beta Hydrolase
U876_15155	ENOG4105NNH	LexA regulated protein
U876_15160	ENOG4105MHQ	Low-potential electron donor to a number of redox enzymes (By similarity)
U876_15170	ENOG41090R7	Ferric uptake
U876_15175	ENOG4105CX6	glutaminyL-tRNA synthetase
U876_15180	ENOG4105E2D	ec 3.2.1.52
U876_15185	ENOG4105CI1	PTS System
U876_15190	ENOG4105CKA	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion (By similarity)
U876_15195	ENOG4105CE4	GlcNAc 6-P deacetylase
U876_15200	ENOG4105E2R	ROK family
U876_15210	ENOG4105DIJ	Phosphoethanolamine transferase
U876_15215	ENOG4105CDY	transcriptional regulatory protein
U876_15220	ENOG4105C9M	aspartyl-trna synthetase
U876_15225	ENOG41081XQ	Conserved Protein
U876_15230	ENOG4105DA6	Catalyzes the conversion of 5-methoxyuridine (mo5U) to uridine-5-oxyacetic acid (cmo5U) at position 34 in tRNA. May also participate in the methylation of uridine-5-oxyacetic acid (cmo5U) to uridine-5-oxyacetic acid methyl ester (mcmo5U) (By similarity)
U876_15235	ENOG4105PFA	Catalyzes the conversion of 5-hydroxyuridine (ho5U) to 5-methoxyuridine (mo5U) at position 34 in tRNA (By similarity)
U876_15255	ENOG4105D3R	alkyl hydroperoxide reductase
U876_15260	ENOG4105C5Q	Transcriptional regulator
U876_15270	ENOG4107TT5	NLP P60 protein
U876_15280	ENOG4107RGH	Aldehyde dehydrogenase
U876_15285	ENOG4107Z3H	Transcriptional regulator, TetR family
U876_15305	ENOG4105C6T	cysteine synthase
U876_15325	ENOG4105UQX	Mate efflux family protein
U876_15345	ENOG4107SQI	penicillin amidase
U876_15350	ENOG4105D95	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin (By similarity)
U876_15360	ENOG4105QVC	MOSC domain-containing protein
U876_15360	ENOG4105QVC	MOSC domain-containing protein
U876_15365	ENOG4107SDU	Methyl-accepting chemotaxis
U876_15370	ENOG4105D0M	Protease HtpX homolog
U876_15375	ENOG4105E78	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity)
U876_15380	ENOG410626R	Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity)
U876_15385	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
U876_15390	ENOG4105CZF	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism (By similarity)
U876_15410	ENOG4105C5S	asparaginyl-tRNA synthetase
U876_15415	ENOG4105DS2	Anaerobic c4-dicarboxylate transporter
U876_15430	ENOG4105CEE	C4-dicarboxylate transporter
U876_15445	ENOG4105KUZ	arsenate reductase
U876_15450	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
U876_15465	ENOG4105C3N	Participates in control of cell volume in low-osmolarity conditions (By similarity)
U876_15485	ENOG410829K	Lysine exporter protein (Lyse ygga)
U876_15490	ENOG4108NVR	Methyl-accepting chemotaxis
U876_15495	ENOG4105RX8	Protein of unknown function (DUF1523)
U876_15510	ENOG4105DU0	nucleoside hydrolase
U876_15515	ENOG4105D3G	Pseudouridine synthase
U876_15520	ENOG4107SXA	Phosphorylase
U876_15525	ENOG4105C0A	alcohol dehydrogenase
U876_15605	ENOG4105YRI	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
U876_15610	ENOG4105K4T	epimerase
U876_15615	ENOG4105VDB	UPF0125 protein
U876_15620	ENOG4108Z1B	Cyclase dehydrase
U876_15625	ENOG4108UH4	Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity)
U876_15700	ENOG4105EFV	Major head subunit
U876_15705	ENOG4108TVE	i protein
U876_15725	ENOG4105QIB	mu-like prophage Flumu protein gp29
U876_15730	ENOG4105CF2	Mu-like prophage FluMu protein GP28
U876_15735	ENOG4108Z6H	mu-like prophage Flumu protein gp27
U876_15850	ENOG4108F3G	Type I restriction-modification system, R subunit
U876_15885	ENOG4105W8I	Transcriptional regulator
U876_15895	ENOG4105BZC	d-serine deaminase
U876_15905	ENOG4108HMX	isocitrate dehydrogenase (NADP)
U876_15910	ENOG4106R3P	AraC family transcriptional regulator
U876_15915	ENOG4105EIP	mannose-6-phosphate isomerase
U876_15930	ENOG4105DM4	PTS System
U876_15940	ENOG4105C87	Aminotransferase class I and II
U876_15945	ENOG4105CI1	PTS System
U876_15950	ENOG4107P2S	Transcriptional regulator
U876_15965	ENOG4105KEG	ribosomal-protein-alanine acetyltransferase
U876_15985	ENOG4105DM4	PTS System
U876_15990	ENOG4105CXY	transporter
U876_15995	ENOG4108YRF	PTS System
U876_16005	ENOG4108R99	pseudouridine synthase
U876_16015	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
U876_16020	ENOG41075W9	High frequency lysogenization protein HflD homolog
U876_16025	ENOG4107QTF	adenylosuccinate lyase
U876_16030	ENOG4105EZE	Cupin 4 family protein
U876_16040	ENOG4108YYD	acetyltransferase
U876_16055	ENOG4108S7T	Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) (By similarity)
U876_16075	ENOG4105M2J	Glutaredoxin
U876_16080	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
U876_16085	ENOG410903C	(LipO)protein
U876_16090	ENOG4105KWW	Biogenesis protein
U876_16095	ENOG4105KWW	Biogenesis protein
U876_16100	ENOG4107QX9	Thiol disulfide interChange protein
U876_16105	ENOG4105DA4	cytochrome c-type biogenesis protein
U876_16110	ENOG4108ZKK	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH (By similarity)
U876_16115	ENOG4105X3C	heme exporter protein
U876_16120	ENOG41060IM	Heme exporter protein
U876_16125	ENOG4105CA5	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes (By similarity)
U876_16140	ENOG4108V3W	Chemotaxis protein, CheW
U876_16150	ENOG4107QJE	Chromosome Partitioning Protein
U876_16155	ENOG4108SEK	ompa motb domain protein
U876_16160	ENOG4105E14	MotA TolQ exbB proton channel
U876_16165	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
U876_16170	ENOG4105CBS	Chea signal transduction histidine kinase
U876_16175	ENOG4108KCC	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P) (By similarity)
U876_16180	ENOG4108VYJ	response regulator receiver protein
U876_16185	ENOG4105DN4	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
U876_16195	ENOG4105FZW	flagellar biosynthesis regulator FlhF
U876_16200	ENOG4105D7B	Flagellar biosynthesis protein flha
U876_16205	ENOG4105D00	flagellar biosynthetic protein flhB
U876_16210	ENOG4105D19	Role in flagellar biosynthesis (By similarity)
U876_16215	ENOG4105VS8	Flagellar biosynthetic protein fliq
U876_16220	ENOG4105CN7	Flagellar biosynthetic protein FliP
U876_16225	ENOG4105VTB	flagellar biosynthesis protein fliO
U876_16230	ENOG4105DD5	Flagellar motor switch protein
U876_16235	ENOG4105D24	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
U876_16255	ENOG4108JIR	Flagellum-specific ATP synthase
U876_16265	ENOG4105CS3	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
U876_16270	ENOG4105C1F	The M ring may be actively involved in energy transduction (By similarity)
U876_16275	ENOG4105VQ0	flagellar hook-basal body complex protein fliE
U876_16285	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
U876_16290	ENOG4105CBM	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 (By similarity)
U876_16300	ENOG4105EUK	rtx toxin RtxA
U876_16315	ENOG4108JJA	ABC, transporter
U876_16320	ENOG4105C42	Type I secretion membrane fusion protein (HlyD
U876_16325	ENOG4108JJA	ABC, transporter
U876_16330	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
U876_16345	ENOG4106KNT	transcriptional regulator
U876_16350	ENOG4105CA9	Pyruvate kinase
U876_16360	ENOG4105BZS	acriflavin resistance protein
U876_16365	ENOG4107QPN	acyl-Coa dehydrogenase
U876_16375	ENOG4107SSZ	Phosphatase
U876_16385	ENOG4107QKC	Oxidoreductase alpha (molybdopterin) subunit
U876_16390	ENOG4107H9G	Necessary for formate dehydrogenase activity (By similarity)
U876_16395	ENOG4105CBN	LysR family transcriptional regulator
U876_16415	ENOG4105KNY	Microcompartments protein
U876_16420	ENOG4105KNY	Microcompartments protein
U876_16425	ENOG4105KNY	Microcompartments protein
U876_16430	ENOG4108EKI	Dehydrogenase
U876_16440	ENOG4108EKI	Dehydrogenase
U876_16445	ENOG4105C6N	Formate acetyltransferase
U876_16450	ENOG4105F1A	Pyruvate formate-lyase
U876_16455	ENOG4105KNY	Microcompartments protein
U876_16460	ENOG4108VPX	Involved in 1,2-propanediol (1,2-PD) degradation by catalyzing the conversion of propanoyl-CoA to propanoyl-phosphate (By similarity)
U876_16505	ENOG4108R66	Conserved Protein
U876_16510	ENOG4105F9F	transposase
U876_16515	ENOG4107RJ1	sodium solute
U876_16525	ENOG4105C9S	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P) (By similarity)
U876_16530	ENOG4105QEK	Transcriptional regulator
U876_16535	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
U876_16540	ENOG4105C1X	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity (By similarity)
U876_16545	ENOG4105E98	transcriptional regulator DeoR family
U876_16550	ENOG4105EDR	glucose galactose transporter
U876_16555	ENOG4105EHF	Converts the aldose L-fucose into the corresponding ketose L-fuculose (By similarity)
U876_16560	ENOG4105CMG	Carbohydrate kinase
U876_16570	ENOG4105NWF	RbsD or FucU transport
U876_16580	ENOG4108JQ5	ABC transporter
U876_16585	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
U876_16595	ENOG4105DEF	Extracellular solute-binding protein, family 5
U876_16605	ENOG4107N1Q	ErfK YbiS YcfS YnhG family protein
U876_16620	ENOG4105EBA	Specifically methylates the adenine in position 1618 of 23S rRNA (By similarity)
U876_16625	ENOG4107TT5	NLP P60 protein
U876_16635	ENOG4107QR8	Thioredoxin
U876_16645	ENOG4105C66	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity)
U876_16650	ENOG4105CIY	formyltetrahydrofolate deformylase
U876_16660	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
U876_16675	ENOG4108VC8	Peptidase family M23
U876_16685	ENOG4105E4C	Lytic transglycosylase catalytic
U876_16690	ENOG4105D8C	Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity)
U876_16695	ENOG4105NHU	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group (By similarity)
U876_16705	ENOG4105EP9	oxidoreductase
U876_16725	ENOG4105CCT	upf0313 protein
U876_16735	ENOG4105BZS	acriflavin resistance protein
U876_16740	ENOG4105J12	Multidrug resistance protein mdtN
U876_16745	ENOG4105BZU	Histidine kinase
U876_16750	ENOG4105D78	K07001 NTE family protein
U876_16755	ENOG4105C8J	)-transporter
U876_16770	ENOG4105UYK	outer membrane protein a
U876_16775	ENOG4105UYK	outer membrane protein a
U876_16780	ENOG4105UYK	outer membrane protein a
U876_16785	ENOG4107R1I	NAD-dependent malic enzyme
U876_16790	ENOG4105ECQ	AraC Family Transcriptional Regulator
U876_16795	ENOG4105UQX	Mate efflux family protein
U876_16800	ENOG4105RKX	Protein of unknown function (DUF2498)
U876_16805	ENOG4105BZU	Histidine kinase
U876_16810	ENOG4105C2W	permease
U876_16815	ENOG4108KMH	lipoate-protein ligase a
U876_16820	ENOG4105BZG	amino acid carrier protein
U876_16845	ENOG4105PTV	Nudix Hydrolase
U876_16865	ENOG4105CJ1	ABC, transporter
U876_16870	ENOG4108V1T	peptidylprolyl cis-trans isomerase
U876_16875	ENOG4106N3A	copper homeostasis protein cutc
U876_16890	ENOG4105ERG	peptidase m48, ste24p
U876_16900	ENOG4105BZU	Histidine kinase
U876_16905	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
U876_16910	ENOG4108ZI4	Glyoxalase Bleomycin resistance protein (Dioxygenase
U876_16915	ENOG4105C04	l-carnitine dehydratase bile acid-inducible protein F
U876_16920	ENOG4105C1G	acyl-Coa dehydrogenase
U876_16925	ENOG4108JU9	GAF modulated sigma54 specific transcriptional regulator Fis family
U876_16930	ENOG4105C26	Dehydrogenase
U876_16940	ENOG4108IPJ	Membrane
U876_16945	ENOG4106YYS	transcriptional regulatory protein
U876_16950	ENOG4105CEQ	signal transduction histidine kinase regulating citrate malate metabolism
U876_16955	ENOG4107R1I	NAD-dependent malic enzyme
U876_16960	ENOG4105D2K	citrate carrier protein
U876_16970	ENOG4108US0	Transcription regulator that can specifically activate or repress expression of target genes (By similarity)
U876_16975	ENOG4105J12	Multidrug resistance protein mdtN
U876_17005	ENOG4108RDD	Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine (By similarity)
U876_17010	ENOG4105CJD	(Anaerobic) ribonucleoside-triphosphate reductase
U876_17020	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
U876_17030	ENOG4105CDB	Required for chromosome condensation and partitioning (By similarity)
U876_17035	ENOG4105EXN	Sulfate transport protein CysZ
U876_17040	ENOG4105EN6	Membrane
U876_17050	ENOG4105EAQ	(twin-arginine translocation) pathway signal
U876_17055	ENOG4105DIT	ErfK YbiS YcfS YnhG family protein
U876_17085	ENOG4107T9C	Alpha amylase catalytic region
U876_17120	ENOG4105BZU	Histidine kinase
U876_17125	ENOG4105D3U	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
U876_17130	ENOG4105C9K	Endothelin-converting enzyme 1
U876_17140	ENOG4105C5H	ABC transporter
U876_17145	ENOG4105KNA	-acetyltransferase
U876_17150	ENOG4105DVH	amino acid
U876_17155	ENOG4105EXG	Transcriptional regulator
U876_17165	ENOG4105C44	Serine transporter
U876_17170	ENOG4105EQ2	LysR family Transcriptional regulator
U876_17180	ENOG4107XGF	functions in a salvage pathway. Uses pyridoxamine (By similarity)
U876_17185	ENOG4105CXN	decarboxylase
U876_17190	ENOG4105D5Q	Arginine ornithine antiporter
U876_17195	ENOG4108M3R	transcriptional activator CadC
U876_17200	ENOG4107QM9	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA (By similarity)
U876_17205	ENOG4105C0B	DNA polymerase III (alpha subunit)
U876_17210	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
U876_17215	ENOG4105D0V	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
U876_17220	ENOG4105DAF	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
U876_17225	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
U876_17230	ENOG4105D7M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
U876_17235	ENOG4108RFI	Molecular chaperone that interacts specifically with outer membrane proteins, thus maintaining the solubility of early folding intermediates during passage through the periplasm (By similarity)
U876_17245	ENOG4105DZP	Membrane-associated zinc metalloprotease
U876_17255	ENOG4105CEA	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity)
U876_17260	ENOG4105KNE	Phosphatidate cytidylyltransferase
U876_17265	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
U876_17270	ENOG4108VCV	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity)
U876_17275	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
U876_17280	ENOG4105CU7	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity)
U876_17285	ENOG4105CE9	30S ribosomal protein S2
U876_17290	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
U876_17295	ENOG4105E1P	Modifies, by uridylylation or deuridylylation the PII (GlnB) regulatory protein (By similarity)
U876_17300	ENOG4105DMJ	Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate (By similarity)
U876_17305	ENOG4108T8E	UPF0325 protein
U876_17310	ENOG4105CI1	PTS System
U876_17315	ENOG4107W52	maltose operon periplasmic protein
U876_17320	ENOG4108KDD	Involved in the transport of maltose and maltodextrins (By similarity)
U876_17325	ENOG4105QDK	Flavodoxin
U876_17330	ENOG4105DR9	pseudouridine synthase
U876_17335	ENOG4105WP7	tRNA pseudouridine synthase C
U876_17360	ENOG4105EXF	Zn-ribbon-containing, possibly nucleic-acid-binding protein
U876_17365	ENOG4108T6E	Interacts with the SecY protein in vivo. May bind preferentially to an uncomplexed state of SecY, thus functioning either as a chelating agent for excess SecY in the cell or as a regulatory factor that negatively controls the translocase function (By similarity)
U876_17370	ENOG4107R1K	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) (By similarity)
U876_17380	ENOG4105BZU	Histidine kinase
U876_17385	ENOG4105EWT	decarboxylase family
U876_17390	ENOG4105CIQ	May have a role in processing of nucleic acids. It is probably not an exonuclease
U876_17395	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
U876_17405	ENOG4105EZ6	Catalyzes the 2'-O-methylation at nucleotide C2498 in 23S rRNA (By similarity)
U876_17410	ENOG4105M08	Membrane
U876_17420	ENOG4105ETT	transcriptional Regulator, LysR family
U876_17425	ENOG4105C8Q	Methyl-accepting chemotaxis
U876_17430	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
U876_17445	ENOG4105CJ2	(LipO)protein
U876_17450	ENOG4105D26	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. The first step is catalyzed by NqrF, which accepts electrons from NADH and reduces ubiquinone-1 to ubisemiquinone by a one-electron transfer pathway (By similarity)
U876_17455	ENOG4108IUB	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
U876_17460	ENOG4105F5D	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
U876_17465	ENOG4106I92	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
U876_17470	ENOG4108J5C	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
U876_17475	ENOG4105DWQ	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
U876_17480	ENOG4105M85	Bola protein
U876_17485	ENOG4105D8J	Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle (By similarity)
U876_17495	ENOG4108R5K	PPIases accelerate the folding of proteins (By similarity)
U876_17505	ENOG4105EYM	Major Facilitator superfamily
U876_17510	ENOG4105DRB	nucleoside-specific channel-forming protein
U876_17515	ENOG4108VPT	UPF0234 protein
U876_17520	ENOG4108JZF	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity)
U876_17525	ENOG4107S0N	DJ-1 family
U876_17530	ENOG4105C7K	acetolactate synthase
U876_17560	ENOG4105CS6	Rhs element vgr protein
U876_17565	ENOG4108WC9	type VI secretion system effector, hcp1 family
U876_17570	ENOG4105VJY	transcriptional regulator
U876_17580	ENOG4105DRC	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity)
U876_17585	ENOG4105CMR	udp-glucose 4-epimerase
U876_17595	ENOG4105EJ7	Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O (By similarity)
U876_17600	ENOG4108RMU	ferritin dps family protein
U876_17625	ENOG4105CV9	cyclopropane-fatty-acyl-phospholipid synthase
U876_17640	ENOG4105EMU	Dehydrogenase
U876_17650	ENOG4105CVP	deoxyribo-dipyrimidine photolyase
U876_17655	ENOG4108XDN	Transcriptional regulator
U876_17660	ENOG4107SEY	Conserved Protein
U876_17690	ENOG4105CQC	Prephenate dehydratase
U876_17740	ENOG4105CS6	Rhs element vgr protein
U876_17750	ENOG4108WC9	type VI secretion system effector, hcp1 family
U876_17835	ENOG4108YGG	dna repair protein
U876_17885	ENOG4105MAW	Antitoxin component of a toxin-antitoxin (TA) module. Labile antitoxin that counteracts the effect of the CbtA (YeeV) toxin. It does not bind to the cognate toxin but instead binds to MreB and FtsZ (the toxin targets), enhancing their polymerization by forming higher-order bundles
U876_17920	ENOG4105F9F	transposase
U876_17940	ENOG4108NF7	phage-type endonuclease
U876_17985	ENOG4105W5Q	DNA repair protein (RadC
U876_17995	ENOG4105EIZ	Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity)
U876_18000	ENOG4105FD2	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) (By similarity)
U876_18020	ENOG4105C9U	ATP-dependent DNA helicase RecQ
U876_18040	ENOG4105C9U	ATP-dependent DNA helicase RecQ
U876_18045	ENOG4105BZK	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair (By similarity)
U876_18070	ENOG4107ZSV	Receptor
U876_18090	ENOG4105E2Y	ABC, transporter
U876_18095	ENOG4108JUA	Transcriptional regulator
U876_18115	ENOG4105EHG	Permease protein
U876_18120	ENOG4108W0P	ABC transporter
U876_18130	ENOG4105DVA	methyltransferase
U876_18165	ENOG4105D8V	Glucose sorbosone dehydrogenase
U876_18175	ENOG4105C8Q	Methyl-accepting chemotaxis
U876_18180	ENOG4105J5J	Outer membrane porin
U876_18185	ENOG4105E1F	short-chain dehydrogenase reductase
U876_18210	ENOG4105CTD	carboxy-peptidase
U876_18225	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
U876_18230	ENOG4105CFP	Peptidase U32
U876_18235	ENOG4105N14	lysine exporter protein LysE YggA
U876_18245	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
U876_18250	ENOG4105C8Q	Methyl-accepting chemotaxis
U876_18255	ENOG4108VYJ	response regulator receiver protein
U876_18265	ENOG4105CBS	Chea signal transduction histidine kinase
U876_18275	ENOG4108V3W	Chemotaxis protein, CheW
U876_18280	ENOG4105C8Q	Methyl-accepting chemotaxis
U876_18285	ENOG4105BZU	Histidine kinase
U876_18290	ENOG4108Z4W	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis (By similarity)
U876_18295	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
U876_18300	ENOG4105C9B	Cysteine desulfurase
U876_18330	ENOG4108NJZ	Sensory box GGDEF EAL domain protein
U876_18335	ENOG4105CFP	Peptidase U32
U876_18340	ENOG4105K5D	4fe-4S ferredoxin iroN-sulfur binding
U876_18350	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
U876_18355	ENOG4105CDU	Replicative dna helicase
U876_18370	ENOG4105BZU	Histidine kinase
U876_18375	ENOG4105CGH	5'-nucleotidase
U876_18395	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
U876_18400	ENOG4108V1T	peptidylprolyl cis-trans isomerase
U876_18410	ENOG4105VRX	Protein slyX homolog
U876_18415	ENOG4108YZY	peptidylprolyl cis-trans isomerase
U876_18420	ENOG4105VKU	nucleicacid-binding protein
U876_18430	ENOG4107R88	Chemotaxis protein (CheV)
U876_18435	ENOG4105DNZ	Alpha Beta Hydrolase
U876_18445	ENOG4105YP7	UPF0270 protein
U876_18450	ENOG4105C6Y	Udp-glucose 6-dehydrogenase
U876_18455	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
U876_18460	ENOG4105CKK	Glycosyl transferase, family 2
U876_18465	ENOG4108I2E	Bifunctional enzyme that catalyzes the oxidative decarboxylation of UDP-glucuronic acid (UDP-GlcUA) to UDP-4-keto- arabinose (UDP-Ara4O) and the addition of a formyl group to UDP-4- amino-4-deoxy-L-arabinose (UDP-L-Ara4N) to form UDP-L-4-formamido- arabinose (UDP-L-Ara4FN). The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides (By similarity)
U876_18470	ENOG4105F73	Catalyzes the deformylation of 4-deoxy-4-formamido-L- arabinose-phosphoundecaprenol to 4-amino-4-deoxy-L-arabinose- phosphoundecaprenol. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides (By similarity)
U876_18475	ENOG4105SA9	Catalyzes the transfer of the L-Ara4N moiety of the glycolipid undecaprenyl phosphate-alpha-L-Ara4N to lipid A. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides (By similarity)
U876_18480	ENOG41060GT	Translocates 4-amino-4-deoxy-L-arabinose- phosphoundecaprenol (alpha-L-Ara4N-phosphoundecaprenol) from the cytoplasmic to the periplasmic side of the inner membrane (By similarity)
U876_18485	ENOG4105PE8	Translocates 4-amino-4-deoxy-L-arabinose- phosphoundecaprenol (alpha-L-Ara4N-phosphoundecaprenol) from the cytoplasmic to the periplasmic side of the inner membrane (By similarity)
U876_18490	ENOG4105CJE	phosphoribulokinase (EC 2.7.1.19)
U876_18505	ENOG4108UKZ	OsmC family
U876_18510	ENOG4107RYR	Transcriptional regulator, Crp Fnr family
U876_18515	ENOG4105DHI	Methyltransferase
U876_18520	ENOG4108M1A	Chitin-binding protein
U876_18525	ENOG4108MA4	Peptidase M66
U876_18535	ENOG4105BZU	Histidine kinase
U876_18545	ENOG4105VMP	Transcriptional regulator
U876_18550	ENOG4105D8G	Major Facilitator superfamily
U876_18555	ENOG4105D05	Receptor
U876_18575	ENOG4105PYN	Pyridoxamine 5-phosphate oxidase-related
U876_18580	ENOG41090JE	Utilization Protein
U876_18590	ENOG4105EHG	Permease protein
U876_18620	ENOG4105D9N	nucleoside
U876_18625	ENOG4107U5R	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate (By similarity)
U876_18645	ENOG4105E4C	Lytic transglycosylase catalytic
U876_18650	ENOG4105DUF	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively (By similarity)
U876_18750	ENOG4105D07	Signal peptide peptidase, SppA
U876_18765	ENOG4105CAR	Terminase, large subunit
U876_18940	ENOG4107R08	Integrase
U876_18945	ENOG4105C5H	ABC transporter
U876_18955	ENOG4105C7N	Xanthine uracil vitamin C permease
U876_18960	ENOG41066UG	Regulatory DnaK co-chaperone. Direct interaction between DnaK and DjlA is needed for the induction of the wcaABCDE operon, involved in the synthesis of a colanic acid polysaccharide capsule, possibly through activation of the RcsB RcsC phosphotransfer signaling pathway. The colanic acid capsule may help the bacterium survive conditions outside the host (By similarity)
U876_18965	ENOG4108S0S	Nucleotidyl transferase
U876_18970	ENOG4105EHM	Aminoglycoside phosphotransferase
U876_18975	ENOG4105E7H	involved in the assembly of LPS in the outer leaflet of the outer membrane. Determines N-hexane tolerance and is involved in outer membrane permeability. Essential for envelope biogenesis (By similarity)
U876_18985	ENOG4105CEZ	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) (By similarity)
U876_18990	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
U876_18995	ENOG4105NWN	ApaG protein
U876_19000	ENOG4105DDT	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP (By similarity)
U876_19010	ENOG4105DEN	Luciferase family
U876_19015	ENOG4108ESY	Metal dependent phosphohydrolase
U876_19030	ENOG4105CEY	Amp-dependent synthetase and ligase
U876_19035	ENOG4105DWD	nucleoside recognition domain protein
U876_19040	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
U876_19045	ENOG4105K46	50S ribosomal protein l27
U876_19050	ENOG4105KK9	This protein binds to 23S rRNA in the presence of protein L20 (By similarity)
U876_19055	ENOG4105EAH	synthase
U876_19065	ENOG4105EPW	hflc protein
U876_19070	ENOG4107QJR	hflk protein
U876_19075	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
U876_19080	ENOG4105KW8	RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity)
U876_19085	ENOG4105DKX	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity)
U876_19090	ENOG4105DC6	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity)
U876_19100	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
U876_19105	ENOG4105K8N	protein family UPF0079, ATPase
U876_19110	ENOG4105DR1	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)
U876_19115	ENOG4105EH2	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity)
U876_19130	ENOG4108JEI	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity)
U876_19135	ENOG4108UMI	ABC transporter, permease
U876_19140	ENOG4105D01	(LipO)protein
U876_19145	ENOG4105MDZ	Transcriptional activator rfaH
U876_19150	ENOG4108N3W	hemolysin secretion protein
U876_19155	ENOG4105BZU	Histidine kinase
U876_19160	ENOG4105BZU	Histidine kinase
U876_19170	ENOG4105C4Q	deoxyguanosinetriphosphate triphosphohydrolase-like protein
U876_19175	ENOG4105BZU	Histidine kinase
U876_19195	ENOG4106173	Uncharacterized protein conserved in bacteria (DUF2057)
U876_19200	ENOG4105EXG	Transcriptional regulator
U876_19210	ENOG4107QWK	SAICAR synthetase
U876_19215	ENOG4107EG0	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
U876_19220	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
U876_19225	ENOG4105RH4	Glycine cleavage system transcriptional repressor
U876_19230	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
U876_19235	ENOG4105XWI	UPF0304 protein
U876_19240	ENOG4105PQ6	UPF0208 membrane protein
U876_19245	ENOG4105C6H	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity)
U876_19250	ENOG4105C6K	Malic enzyme
U876_19255	ENOG4108ZP8	Acetolactate synthase small subunit
U876_19260	ENOG4105C7K	acetolactate synthase
U876_19275	ENOG4105YVM	Phosphoesterase, PA-phosphatase related
U876_19285	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
U876_19295	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
U876_19300	ENOG4105MQS	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
U876_19315	ENOG4105DP9	ABC transporter
U876_19320	ENOG4106SMU	thiamine transporter membrane protein
U876_19325	ENOG4107T0D	ABC, transporter
U876_19330	ENOG4108IAB	Phoh family
U876_19340	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
U876_19370	ENOG4105BZK	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair (By similarity)
U876_19375	ENOG4105D3G	Pseudouridine synthase
U876_19385	ENOG4105BZU	Histidine kinase
U876_19395	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
U876_19400	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
U876_19405	ENOG4107QI1	Mate efflux family protein
U876_19410	ENOG4108YH1	overproduction of this protein in Escherichia coli inhibits the F plasmid-mediated exclusion of bacteriophage T7
U876_19415	ENOG4108IJ0	Aspartate ammonia-lyase
U876_19420	ENOG4105DS2	Anaerobic c4-dicarboxylate transporter
U876_19430	ENOG4105EV4	Multidrug resistance protein mdtH
U876_19455	ENOG4105D9U	N-acetyltransferase
U876_19465	ENOG4105D9R	oxidoreductase
U876_19475	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
U876_19480	ENOG4105CSA	Coproporphyrinogen iii oxidase
U876_19490	ENOG4105NAE	bifunctional deaminase-reductase domain protein
U876_19500	ENOG4105DC1	bifunctional purine biosynthesis protein purh
U876_19505	ENOG4105C12	Phosphoribosylglycinamide synthetase
U876_19535	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
U876_19540	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
U876_19545	ENOG4105KTH	gatB Yqey
U876_19550	ENOG4105VCC	30S ribosomal protein S21
U876_19555	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
U876_19570	ENOG4108UM1	dedA family
U876_19575	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
U876_19580	ENOG4105CV2	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates (By similarity)
U876_19585	ENOG4106NZV	Responsible for synthesis of pseudouridine from uracil- 13 in transfer RNAs (By similarity)
U876_19590	ENOG4108UH8	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (By similarity)
U876_19595	ENOG4105CE5	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) (By similarity)
U876_19600	ENOG4105XX3	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity)
U876_19605	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
U876_19610	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
U876_19615	ENOG4105DXN	mazG family
U876_19620	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
U876_19625	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
U876_19630	ENOG4105BZU	Histidine kinase
U876_19635	ENOG4108W15	Protein of unknown function (DUF1456)
U876_19640	ENOG4108VBV	N-Acetylmuramoyl-L-alanine amidase
U876_19645	ENOG4105E98	transcriptional regulator DeoR family
U876_19650	ENOG4105C6Q	that is required for full activity and stability of the Y subunit. Could have a chaperone-like function for the proper and stable folding of
U876_19655	ENOG4105E70	isomerase
U876_19660	ENOG4108RG5	PTS system N-acetylgalactosamine-specific transporter subunit IIB
U876_19670	ENOG4105F3R	pts system mannose fructose sorbose family iid
U876_19675	ENOG4108YTN	IIa component
U876_19680	ENOG4105CE4	GlcNAc 6-P deacetylase
U876_19685	ENOG4105D2N	Aldolase
U876_19695	ENOG4105CSZ	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate (By similarity)
U876_19700	ENOG41071DT	Involved in DNA repair and RecF pathway recombination (By similarity)
U876_19715	ENOG4105C3F	Signal peptidase i
U876_19720	ENOG4105C4S	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity)
U876_19740	ENOG4105EMN	RNA polymerase sigma factor
U876_19745	ENOG4108IYU	L-aspartate oxidase
U876_19755	ENOG4105Y75	tpr repeat protein
U876_19760	ENOG4106XY2	Folate-binding protein involved in regulating the level of ATP-DnaA and in the modification of some tRNAs. It is probably a key factor in regulatory networks that act via tRNA modification, such as initiation of chromosomal replication (By similarity)
U876_19780	ENOG4105VF7	tolerance protein
U876_19785	ENOG4105CSG	Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps (By similarity)
U876_19795	ENOG4105CJP	fad dependent oxidoreductase
U876_19800	ENOG4105D2N	Aldolase
U876_19805	ENOG4105BZA	Phosphoglycerate kinase
U876_19810	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
U876_19815	ENOG4105DKQ	ROK family
U876_19820	ENOG4105CFZ	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III (By similarity)
U876_19825	ENOG4105E09	nadh pyrophosphatase
U876_19830	ENOG4105C26	Dehydrogenase
U876_19835	ENOG4106MWK	domain protein
U876_19840	ENOG4105EYW	Ion transport protein
U876_19845	ENOG4105C8Q	Methyl-accepting chemotaxis
U876_19855	ENOG4105CE6	Adenylation and deadenylation of glutamate--ammonia ligase (By similarity)
U876_19880	ENOG4108IYI	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine (By similarity)
U876_19885	ENOG4105E5Q	amino acid AbC transporter
U876_19890	ENOG4105E5Q	amino acid AbC transporter
U876_19895	ENOG4105CDA	abc transporter atp-binding protein
U876_19900	ENOG4105CT1	(ABC) transporter
U876_19905	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
U876_19910	ENOG4105DJY	efflux transporter, rnd family, mfp subunit
U876_19915	ENOG4105E3W	Two component transcriptional regulator (Winged helix family
U876_19920	ENOG4105E0F	Histidine kinase
U876_19955	ENOG4105EA8	2-Nitropropane dioxygenase
U876_19980	ENOG4105CA0	peroxidase
U876_19985	ENOG4107V4F	S-adenosyl-l-methionine hydroxide adenosyltransferase
U876_20005	ENOG4105C1J	atp-dependent rna helicase
U876_20015	ENOG4107YH7	Beta-lactamase (EC 3.5.2.6)
U876_20035	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
U876_20040	ENOG4105DWY	Agmatine deiminase
U876_20055	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
U876_20060	ENOG4108MJ3	acetyltransferase
U876_20085	ENOG4105BZU	Histidine kinase
U876_20090	ENOG4105BZU	Histidine kinase
U876_20100	ENOG4107R4Q	Functions as an ATPase. May play a role in metal insertion (metal-chelatase) or as a chaperone (By similarity)
U876_20110	ENOG41080E2	ribosomal-protein-alanine acetyltransferase
U876_20120	ENOG4108IQE	Amp-dependent synthetase and ligase
U876_20130	ENOG4105D9M	gamma-glutamylcysteine synthetase
U876_20140	ENOG4105W39	Membrane
U876_20165	ENOG4105DP0	ferredoxin-NADP reductase
U876_20170	ENOG4105K9Q	Binds to the 23S rRNA (By similarity)
U876_20175	ENOG4105VH8	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity)
U876_20180	ENOG4108ZDX	Binds together with S18 to 16S ribosomal RNA (By similarity)
U876_20185	ENOG4105C56	H( )-stimulated, divalent metal cation uptake system (By similarity)
U876_20215	ENOG4105C2N	RNA methyltransferase TrmH family group 3
U876_20220	ENOG4105C40	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity)
U876_20225	ENOG4106TD9	Diguanylate cyclase
U876_20230	ENOG4106762	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD) (By similarity)
U876_20240	ENOG4108YZA	Nitrogen regulatory protein pii
U876_20245	ENOG4105C4K	Nad synthetase
U876_20305	ENOG4105C48	Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) (By similarity)
U876_20310	ENOG41090X3	Peptidyl-prolyl cis-trans isomerase
U876_20315	ENOG4105M02	This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity)
U876_20320	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
U876_20325	ENOG4105DTN	riboflavin biosynthesis protein ribF
U876_20330	ENOG4105CJR	Integral membrane protein (MviN
U876_20335	ENOG4105KQV	Binds directly to 16S ribosomal RNA (By similarity)
U876_20340	ENOG41080HT	Transcriptional regulator, arsr family
U876_20345	ENOG41063Z6	transcriptional regulator, lysR family
U876_20355	ENOG4105DRC	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity)
U876_20360	ENOG4105C0V	Provides the sole de novo source of dTMP for DNA biosynthesis (By similarity)
U876_20365	ENOG4105C3B	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity)
U876_20370	ENOG4108HRM	phosphoenolpyruvate--protein phosphotransferase
U876_20375	ENOG4105EJF	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity)
U876_20380	ENOG4105IRT	Sequence-specific endonuclease that cleaves unmethylated GATC sequences. It is involved in DNA mismatch repair (By similarity)
U876_20390	ENOG4108YY1	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity)
U876_20395	ENOG4105D6X	Specifically methylates guanosine-37 in various tRNAs (By similarity)
U876_20400	ENOG4108ZR6	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity)
U876_20405	ENOG4105K5M	30s ribosomal protein S16
U876_20410	ENOG4105CB9	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
U876_20415	ENOG4106KVJ	cytochrome C assembly protein
U876_20420	ENOG4108JU6	CBS domain protein
U876_20430	ENOG4105CJJ	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity)
U876_20435	ENOG4108UV7	flagellar protein motX
U876_20440	ENOG4105C80	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
U876_20445	ENOG4105DMR	ABC, transporter
U876_20450	ENOG4105GBT	ABC transporter
U876_20455	ENOG4106PMH	Extracellular solute-binding protein family 3
U876_20460	ENOG4105E5Z	arginine transporter ATP-binding subunit
U876_20465	ENOG410682Y	Regulates arginine biosynthesis genes (By similarity)
U876_20470	ENOG4105EZR	dyp-type peroxidase family protein
U876_20475	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
U876_20490	ENOG4108YZA	Nitrogen regulatory protein pii
U876_20495	ENOG4108YZN	class I peptide chain release factor
U876_20505	ENOG4105D9N	nucleoside
U876_20510	ENOG4105HEI	LysR family (Transcriptional regulator
U876_20525	ENOG4105BZW	Glycerate kinase
U876_20530	ENOG4107QQ0	gntp family
U876_20535	ENOG4108IXP	Carbohydrate diacid transcriptional activator CdaR
U876_20545	ENOG4105XTV	UPF0231 protein
U876_20560	ENOG4107RHT	methyl-accepting chemotaxis sensory transducer with Pas Pac sensor
U876_20565	ENOG4108QYW	Bacterial hemolysins are exotoxins that attack blood cell membranes and cause cell rupture. Beta-hemolysin is a phospholipase C with specific activity toward sphingomyelins. Has a high specificity for sphingomyelin, hydrolyzes lysophosphatidylcholine at a much lower rate, but has no activity towards phosphatidylcholine, phosphatidylethanolamine, or phosphatidylserine (By similarity)
U876_20580	ENOG4105C1J	atp-dependent rna helicase
U876_20590	ENOG4108V1J	Has antioxidant activity. Could remove peroxides or H(2)O(2) (By similarity)
U876_20620	ENOG4105CGF	Aromatic amino acid aminotransferase
U876_20635	ENOG41076CZ	activating enzyme
U876_20640	ENOG4105G0K	glycine radical enzyme YjjI family
U876_20660	ENOG4107RE3	peptidase, S41
U876_20690	ENOG4108N3W	hemolysin secretion protein
U876_20695	ENOG4108M1A	Chitin-binding protein
U876_20700	ENOG4107R11	Transcriptional regulator
U876_20710	ENOG4108IJ6	ABC transporter
U876_20715	ENOG4105ECW	sulfate abc transporter
U876_20720	ENOG4108I5D	sulfate abc transporter
U876_20730	ENOG4105DE7	Sulfate ABC transporter periplasmic sulfate-binding protein
U876_20735	ENOG4107PU6	Membrane
U876_20740	ENOG4108UW5	maltose o-acetyltransferase
U876_20765	ENOG4105CH7	arginosuccinase
U876_20770	ENOG4105CDH	Citrulline--aspartate ligase
U876_20780	ENOG4105CAS	nag kinase
U876_20785	ENOG4105C0N	N-acetylglutamate semialdehyde dehydrogenase
U876_20795	ENOG4105CCA	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle (By similarity)
U876_20805	ENOG4105CFH	Aspartokinase
U876_20810	ENOG4105C28	cystathionine
U876_20815	ENOG4105GGQ	This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis (By similarity)
U876_20820	ENOG41086D8	Transcriptional regulator
U876_20825	ENOG4108Z7R	Chaperone CsaA
U876_20830	ENOG4105C44	Serine transporter
U876_20835	ENOG4108RNI	3'(2')5'-bisphosphate nucleotidase
U876_20840	ENOG4107RK2	ADP-ribose diphosphatase NudE
U876_20845	ENOG4107Y3D	HAD-superfamily hydrolase subfamily IA variant 3
U876_20850	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
U876_20855	ENOG4108UDW	Transcriptional regulator, luxr family
U876_20900	ENOG4108VAU	general secretion pathway protein G
U876_20905	ENOG4105D7Q	type ii secretion system
U876_20910	ENOG4107QHF	type ii secretion system protein e
U876_20915	ENOG4105GVR	general secretion pathway protein D
U876_20925	ENOG4105VEJ	Heat shock protein
U876_20930	ENOG4105F4C	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress (By similarity)
U876_20935	ENOG4105DJ1	Phosphoenolpyruvate Carboxylase
U876_20950	ENOG4105VXR	cytoplasmic protein
U876_20955	ENOG4108R6G	acetyltransferase
U876_20960	ENOG4108XTF	Outer Membrane Lipoprotein
U876_20965	ENOG4107RNS	bifunctional 2',3'-cyclic nucleotide 2'-phosphodiesterase 3'-nucleotidase periplasmic
U876_20970	ENOG4108ZUB	Lysine exporter protein (Lyse ygga)
U876_20975	ENOG4105VJY	transcriptional regulator
U876_20980	ENOG4105NNS	Autoinducer synthesis protein
U876_20985	ENOG4105CXD	Specific inhibitor of chromosomal initiation of replication in vitro. Binds the three 13-mers in the origin (oriC) to block initiation of replication (By similarity)
U876_20990	ENOG4108IEC	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction (By similarity)
U876_21010	ENOG4105CTS	PTS system mannitol-specific
U876_21015	ENOG4107SQ3	mannitol-1-phosphate 5-dehydrogenase
U876_21020	ENOG4105E61	Mannitol repressor protein
U876_21025	ENOG4105C3N	Participates in control of cell volume in low-osmolarity conditions (By similarity)
U876_21050	ENOG4108UPT	UPF0178 protein
U876_21065	ENOG4107K5X	Membrane-bound metal-dependent hydrolase
U876_21070	ENOG4105D9N	nucleoside
U876_21075	ENOG4105C1J	atp-dependent rna helicase
U876_21100	ENOG4105EIS	1,4-dihydroxy-2-naphthoate octaprenyltransferase
U876_21105	ENOG4105E4F	Isochorismate synthase
U876_21110	ENOG4105C4A	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC) (By similarity)
U876_21115	ENOG4107J5P	Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC). Is also able to catalyze the hydrolysis of the thioester bond in palmitoyl-CoA in vitro (By similarity)
U876_21120	ENOG4108IPT	Naphthoate synthase
U876_21125	ENOG4105DNI	Converts SHCHC to OSB (By similarity)
U876_21130	ENOG4105CEY	Amp-dependent synthetase and ligase
U876_21145	ENOG4108MDY	Fimbrial
U876_21150	ENOG4108FZ9	Chaperone
U876_21155	ENOG4106PG1	outer membrane usher protein
U876_21165	ENOG4105HMV	Fimbrial protein
U876_21175	ENOG4107MM9	BNR Asp-box repeat-containing protein
U876_21180	ENOG4108UB4	uncharacterized protein ygjQ
U876_21185	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
U876_21195	ENOG4107IFA	Lipase (EC 3.1.1.3)
U876_21215	ENOG4105KNR	Activates the small RNA gene sgrS under glucose- phosphate stress conditions as well as yfdZ. Represses its own transcription under both stress and non-stress conditions. Might act as a sensor of the intracellular accumulation of phosphoglucose by binding these molecules in its C-terminal solute-binding domain (By similarity)
U876_21225	ENOG4108IQK	o-acetylhomoserine
U876_21235	ENOG4108I6A	alcohol dehydrogenase
U876_21250	ENOG4105DZW	Dipeptidase
U876_21255	ENOG4105EMU	Dehydrogenase
U876_21275	ENOG4105KT7	mgtC SapB transporter
U876_21295	ENOG4105E0M	Sulfatase
U876_21300	ENOG4108YXU	transcriptional regulator AsnC family
U876_21310	ENOG4105CVG	Homoserine O-transsuccinylase
U876_21315	ENOG4105E4Y	Endoribonuclease that initiates mRNA decay (By similarity)
U876_21320	ENOG4108I62	cina-like protein
U876_21335	ENOG4105CJ1	ABC, transporter
U876_21350	ENOG410667J	hydrolase
U876_21355	ENOG4108Z86	Glutamine amidotransferase
U876_21365	ENOG4107RYR	Transcriptional regulator, Crp Fnr family
U876_21375	ENOG4105DFC	had-superfamily hydrolase, subfamily ia, variant
U876_21380	ENOG4108IYS	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
U876_21390	ENOG4105E4Z	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan (By similarity)
U876_21395	ENOG4105CU5	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity)
U876_21400	ENOG4105XQ6	frataxin-like protein
U876_21405	ENOG4106CJB	Phospholipase Carboxylesterase
U876_21410	ENOG4107T0K	Adenylate cyclase
U876_21415	ENOG4105D6W	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity)
U876_21420	ENOG41076E6	Uroporphyrinogen-III Synthase
U876_21425	ENOG4105ECF	c-methyltransferase
U876_21440	ENOG4105CBT	Fructose-1,6-bisphosphatase
U876_21455	ENOG4105E0K	tonB-dependent siderophore receptor
U876_21480	ENOG4105KVH	Transcriptional regulator
U876_21485	ENOG4105N0V	mono-oxygenase ydhR
U876_21500	ENOG4108TPP	exopolysaccharide synthesis
U876_21505	ENOG4105C44	Serine transporter
U876_21510	ENOG4105BZU	Histidine kinase
U876_21525	ENOG4108WEF	Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1B (PBP1b) (By similarity)
U876_21540	ENOG4105D41	biosynthesis protein thiH
U876_21545	ENOG4105CA8	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity)
U876_21555	ENOG4105D06	uba thif-type nad fad binding protein
U876_21560	ENOG4108UV6	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity)
U876_21565	ENOG4105CBF	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction (By similarity)
U876_21570	ENOG4107Y8H	Aerolysin toxin
U876_21585	ENOG4105ETX	regulatoR
U876_21595	ENOG4105CWM	branched-chain amino acid transport system II carrier protein
U876_21600	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
U876_21605	ENOG4105C3R	Methionine synthase
U876_21610	ENOG4105EEQ	Na H antiporter
U876_21645	ENOG41090ED	Protein with unknown function (DUF469)
U876_21655	ENOG4105UYK	outer membrane protein a
U876_21660	ENOG4106PG1	outer membrane usher protein
U876_21665	ENOG4106P2F	Pfam:Pili_assembly_C
U876_21715	ENOG4108HU6	Metal dependent phosphohydrolase
U876_21725	ENOG4105CGZ	zinc metallopeptidase
U876_21730	ENOG4105F0S	class B acid phosphatase
U876_21745	ENOG4107SDU	Methyl-accepting chemotaxis
U876_21750	ENOG4107MMM	Anti-sigma-factor antagonist
U876_21755	ENOG4105QD0	anti-sigma regulatory factor serine threonine protein kinase
U876_21760	ENOG4105BZU	Histidine kinase
U876_21765	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
U876_21775	ENOG4105CSH	Transporter
U876_21790	ENOG4105E15	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
U876_21795	ENOG4105C5Y	PTS System
U876_21810	ENOG4108PSC	Represses the expression of the murPQ operon involved in the uptake and degradation of N-acetylmuramic acid (MurNAc). Binds to two adjacent inverted repeats within the operator region. MurNAc 6-phosphate, the substrate of MurQ, is the specific inducer that weakens binding of MurR to the operator (By similarity)
U876_21815	ENOG4105D1U	peptidase U62 modulator of DNA gyrase
U876_21830	ENOG4105QD6	exported protein
U876_21835	ENOG4105C03	ribonuclease
U876_21840	ENOG4108Z03	MAF-like protein
U876_21845	ENOG4105VQ7	Rod shape-determining protein MreD
U876_21850	ENOG4105N3I	Involved in formation and maintenance of cell shape (By similarity)
U876_21855	ENOG4105DFF	Rod shape-determining protein mreb
U876_21880	ENOG4106855	Competence protein
U876_21900	ENOG4105D7Q	type ii secretion system
U876_21905	ENOG4107QHF	type ii secretion system protein e
U876_21915	ENOG4108WTW	DNA transposition protein
U876_21920	ENOG4105GVR	general secretion pathway protein D
U876_21950	ENOG41062P1	Diguanylate cyclase phosphodiesterase
U876_21955	ENOG4107XTP	(EAL) domain protein
U876_21960	ENOG4105EWV	Sodium calcium exchanger membrane region
U876_21965	ENOG4105C84	Histidine ammonia-lyase
U876_21970	ENOG4105CGP	Urocanate hydratase
U876_21975	ENOG41088SP	formiminoglutamate hydrolase
U876_21980	ENOG4105CI2	imidazolone-5-propionate hydrolase
U876_21985	ENOG4105CZE	histidine utilization repressor
U876_21990	ENOG41077A9	carbonic anhydrase
U876_22000	ENOG4105CRP	Part of the ABC transporter FtsEX involved in
U876_22005	ENOG4105CAK	Cell division ATP-binding protein ftsE
U876_22010	ENOG4105CCP	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
U876_22015	ENOG4106H78	methyltransferase
U876_22030	ENOG4105EJ2	Transcriptional regulator
U876_22040	ENOG4107RZC	phospholipase d
U876_22050	ENOG4105E4C	Lytic transglycosylase catalytic
U876_22065	ENOG4105WKS	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity)
U876_22075	ENOG41076UM	multiple antibiotic resistance (MarC)-related protein
U876_22080	ENOG4105VVZ	metal-binding protein
U876_22095	ENOG4105JQN	Transcriptional regulator
U876_22110	ENOG4107FS9	Membrane
U876_22135	ENOG4105CUG	Oligopeptidase b
U876_22150	ENOG4105EMU	Dehydrogenase
U876_22155	ENOG4108W5M	transcriptional regulator
U876_22160	ENOG4108K2R	Glutathione-regulated potassium-efflux system ancillary protein
U876_22210	ENOG4108ZT0	50S ribosomal protein l17
U876_22215	ENOG4105CTF	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
U876_22220	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
U876_22225	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
U876_22230	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
U876_22235	ENOG4105CGG	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity)
U876_22240	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
U876_22245	ENOG4105VPB	50S ribosomal protein L30
U876_22250	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
U876_22255	ENOG4105K4C	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity)
U876_22260	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
U876_22265	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
U876_22270	ENOG4105VBI	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
U876_22275	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
U876_22280	ENOG4105KAR	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity)
U876_22285	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
U876_22290	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
U876_22295	ENOG41083MP	50s ribosomal protein l29
U876_22300	ENOG4108R70	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity)
U876_22305	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
U876_22310	ENOG4105KAP	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity)
U876_22315	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
U876_22320	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
U876_22325	ENOG41080KG	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
U876_22330	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
U876_22335	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
U876_22340	ENOG4108Z10	Involved in the binding of tRNA to the ribosomes (By similarity)
U876_22350	ENOG4105E0F	Histidine kinase
U876_22355	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
U876_22360	ENOG4108RRZ	Transcription elongation factor GreB
U876_22365	ENOG4105BZM	domain protein
U876_22385	ENOG4105D3C	The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters (By similarity)
U876_22390	ENOG4105MJ2	Competence protein
U876_22395	ENOG4107RUK	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins (By similarity)
U876_22400	ENOG4105CSF	NADPH-dependent glycerol-3-phosphate dehydrogenase
U876_22405	ENOG4105IX2	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA (By similarity)
U876_22410	ENOG4107YZP	Rhodanese domain protein
U876_22415	ENOG4105CJI	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
U876_22420	ENOG41063SB	peptidase
U876_22430	ENOG4105DIQ	Transcriptional regulator
U876_22435	ENOG4108UHU	Aldolase
U876_22440	ENOG4105C01	Dihydroxy-acid dehydratase
U876_22445	ENOG4108Z67	carbohydrate kinase, thermoresistant glucokinase family
U876_22450	ENOG4105C6Z	Gluconate
U876_22455	ENOG4105JIM	Phosphatidylserine synthase
U876_22460	ENOG4105CB5	ATP-dependent DNA helicase recG
U876_22470	ENOG4105SUU	thioesterase domain
U876_22480	ENOG4108YYA	Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine (By similarity)
U876_22485	ENOG4107S2Z	UPF0761 membrane protein
U876_22495	ENOG4105C5F	glutamine synthetase
U876_22505	ENOG4105CUX	Signal transduction histidine kinase
U876_22510	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
U876_22515	ENOG4105EKD	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism (By similarity)
U876_22520	ENOG4105D4P	Coproporphyrinogen iii oxidase
U876_22525	ENOG4105XCT	Protein of unknown function (DUF2489)
U876_22530	ENOG4105ZR3	A GTPase-activating protein (GAP) that modifies Der EngA GTPase function. May play a role in ribosome biogenesis (By similarity)
U876_22540	ENOG4106RE7	Cytochrome
U876_22545	ENOG4105WHM	Necessary for normal cell division and for the maintenance of normal septation (By similarity)
U876_22550	ENOG4105SG3	Protein of unknown function (DUF1488)
U876_22555	ENOG4105E2X	shikimate dehydrogenase
U876_22560	ENOG4105DBS	Key enzyme in heme biosynthesis. Catalyzes the oxidative decarboxylation of propionic acid side chains of rings A and B of coproporphyrinogen III (By similarity)
U876_22565	ENOG4105EK0	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
U876_22575	ENOG4108WI1	Dna topoisomerase
U876_22580	ENOG4108RPN	Protein smg homolog
U876_22585	ENOG4105C79	DNA protecting protein DprA
U876_22595	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
U876_22600	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
U876_22605	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
U876_22610	ENOG4105C1A	potassium transporter peripheral membrane
U876_22615	ENOG4105D37	Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA (By similarity)
U876_22640	ENOG4108TFM	Kinase, PfkB family
U876_22645	ENOG4105DCF	alanine dehydrogenase
U876_22650	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
U876_22655	ENOG4105C26	Dehydrogenase
U876_22665	ENOG4108JCI	Transcriptional regulator
U876_22670	ENOG4105C26	Dehydrogenase
U876_22680	ENOG4105FR1	rard protein
U876_22685	ENOG4105ECQ	AraC Family Transcriptional Regulator
U876_22695	ENOG4105C52	Atpase, p-type (Transporting), had superfamily, subfamily ic
U876_22700	ENOG4105CUC	YeeE YedE family protein
U876_22705	ENOG410829K	Lysine exporter protein (Lyse ygga)
U876_22715	ENOG4108YH8	Covalently attaches a chromophore to Cys residue(s) of phycobiliproteins (By similarity)
U876_22740	ENOG41061EV	selenium-binding protein YdfZ
U876_22750	ENOG4105HEI	LysR family (Transcriptional regulator
U876_22755	ENOG4108UK5	Transposase
U876_22765	ENOG4105C4R	Atp-dependent dna helicase
U876_22770	ENOG4105DIH	basic membrane
U876_22775	ENOG4108JQ9	ABC transporter
U876_22785	ENOG4105UIB	(ABC) transporter
U876_22795	ENOG4105CC0	LysR family Transcriptional regulator
U876_22815	ENOG4105E46	N-alpha,N-alpha,N-alpha-trimethyl-L-histidine metabolic process
U876_22820	ENOG4105DHU	Bile acid
U876_22825	ENOG4105E5D	amino acid
U876_22830	ENOG4108Y51	tRNA-binding protein
U876_22835	ENOG4105E5D	amino acid
U876_22840	ENOG4105FK9	beta-D-galactosidase beta subunit
U876_22845	ENOG4105CNT	hydrolase family 2
U876_22850	ENOG4105CQ4	Transcriptional regulator
U876_22885	ENOG4108Z0R	Transferase
U876_22890	ENOG4105C2M	dna polymerase I
U876_22895	ENOG4108556	Isoprenoid biosynthesis protein with amidotransferase-like domain
U876_22900	ENOG41065UX	Non-essential, abundant cell division factor that is required for proper Z-ring formation. It is recruited early to the divisome by direct interaction with FtsZ, stimulating Z-ring assembly and thereby promoting cell division earlier in the cell cycle. Its recruitment to the Z-ring requires functional FtsA or ZipA (By similarity)
U876_22910	ENOG4105D7W	serine acetyltransferase
U876_22920	ENOG4105E3W	Two component transcriptional regulator (Winged helix family
U876_22925	ENOG4105E0F	Histidine kinase
U876_22930	ENOG4108UIQ	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity)
U876_22935	ENOG4107R73	Mate efflux family protein
U876_22950	ENOG4105DS7	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity)
U876_22955	ENOG4105E55	glycerol-3-phosphate acyltransferase
U876_22960	ENOG4105C4G	Synthesis of 3-octaprenyl-4-hydroxybenzoate (By similarity)
U876_22965	ENOG4105VEI	Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4- hydroxybenzoate (4HB) for the ubiquinone pathway (By similarity)
U876_22970	ENOG4105X6C	Flagellar basal body-associated protein FliL
U876_22990	ENOG4105D3Z	quinone oxidoreductase, yhdh yhfp family
U876_22995	ENOG4105DIQ	Transcriptional regulator
U876_23015	ENOG4105D8A	3-Deoxy-D-manno-octulosonic-acid transferase
U876_23020	ENOG4105XA0	heptosyltransferase ii
U876_23025	ENOG4106WTF	Glycosyl transferase, family 2
U876_23030	ENOG4105M5K	heptosyltransferase
U876_23035	ENOG4108ZEF	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity)
U876_23040	ENOG4108MJ5	VirK protein
U876_23045	ENOG4105ERD	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity)
U876_23055	ENOG4105W0E	50S ribosomal protein L33
U876_23060	ENOG4105KDC	50s ribosomal protein l28
U876_23065	ENOG4105W5Q	DNA repair protein (RadC
U876_23070	ENOG4105CJS	Phosphopantothenoylcysteine decarboxylase
U876_23075	ENOG4108Z1K	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA (By similarity)
U876_23080	ENOG4105EC0	Required for nucleoid occlusion (NO) phenomenon, which prevents Z-ring formation and cell division over the nucleoid. Acts as a DNA-associated cell division inhibitor that binds simultaneously chromosomal DNA and FtsZ, and disrupts the assembly of FtsZ polymers. SlmA-DNA-binding sequences (SBS) are dispersed on non-Ter regions of the chromosome, preventing FtsZ polymerization at these regions (By similarity)
U876_23085	ENOG4105D64	Mechanosensitive ion channel
U876_23095	ENOG4107QP8	phosphohexose isomerase
U876_23100	ENOG4105C6M	Alpha-keto-beta-hydroxylacyl reductoisomerase
U876_23105	ENOG4105EMY	transcriptional regulator
U876_23120	ENOG4105CD5	CoA-binding domain protein
U876_23145	ENOG4108RR8	protoporphyrinogen oxidase
U876_23150	ENOG4105D37	Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA (By similarity)
U876_23155	ENOG4108ZK7	protein family UPF0029, Impact, N-terminal protein
U876_23160	ENOG4105D9Y	Splits dipeptides with a prolyl residue in the C- terminal position (By similarity)
U876_23165	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
U876_23170	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
U876_23175	ENOG4105CHU	acetyl-coa acetyltransferase
U876_23180	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
U876_23185	ENOG4105E0F	Histidine kinase
U876_23200	ENOG41082K8	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Interacts with IscS and stimulates its activity. Then, accepts a sulfur from IscS and transfers it in turn to TusD (By similarity)
U876_23205	ENOG4105M4H	endoribonuclease L-psp
U876_23210	ENOG4108ZG0	Ompa motb domain protein
U876_23215	ENOG4105D3W	isochorismatase
U876_23220	ENOG4108R3E	Dna-3-methyladenine glycosylase i
U876_23225	ENOG4108HMW	glycyl-tRNA synthetase, alpha subunit
U876_23230	ENOG4105C38	Glycyl-tRNA synthetase beta subunit
U876_23245	ENOG4107RIQ	Sulfate adenylate transferase
U876_23265	ENOG4105CIC	tryptophan-specific transport protein
U876_23270	ENOG4105HEE	Binding Domain protein
U876_23280	ENOG4108EQM	faD-dependent pyridine nucleotide-disulfide oxidoreductase
U876_23285	ENOG4105CNW	domain protein
U876_23290	ENOG4108JUA	Transcriptional regulator
U876_23295	ENOG4105FDP	GntR family transcriptional regulator
U876_23300	ENOG4105CI1	PTS System
U876_23305	ENOG4105F8D	glycoside hydrolase family 4
U876_23310	ENOG4105ETE	Transcriptional regulator (LacI family
U876_23315	ENOG4105CP9	extracellular ligand-binding receptor
U876_23320	ENOG4105C32	Amino acid ABC transporter (Permease)
U876_23325	ENOG4105CF8	branched-chain amino acid ABC transporter, permease
U876_23330	ENOG4105C0Z	ABC transporter
U876_23335	ENOG4108IV0	ABC, transporter
U876_23350	ENOG4105M78	Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide (By similarity)
U876_23365	ENOG4105W0Z	cytoplasmic protein
U876_23370	ENOG4107QK7	reductase
U876_23375	ENOG4105D3H	Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol (By similarity)
U876_23385	ENOG4105C4P	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity)
U876_23390	ENOG4105K63	Thioredoxin
U876_23395	ENOG4105C1J	atp-dependent rna helicase
U876_23400	ENOG4105C9X	ppx gppa phosphatase
U876_23415	ENOG4105FFN	Specifically methylates the guanosine in position 1516 of 16S rRNA (By similarity)
U876_23420	ENOG4105BZU	Histidine kinase
U876_23425	ENOG4105DGW	oligopeptidase A
U876_23430	ENOG4105D52	delta-aminolevulinic acid dehydratase
U876_23435	ENOG4105F8V	Hydrolase, tatD family
U876_23440	ENOG4105DCX	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity)
U876_23445	ENOG4105X8U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation (By similarity)
U876_23450	ENOG4105WKS	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity)
U876_23455	ENOG4105CNK	Required, probably indirectly, for the hydroxylation of 2-octaprenylphenol to 2-octaprenyl-6-hydroxy-phenol, the fourth step in ubiquinone biosynthesis (By similarity)
U876_23460	ENOG4105JC1	sterol-binding domain protein
U876_23470	ENOG4105WMR	Protein CrcB homolog
U876_23475	ENOG4105DZC	cytosine deaminase
U876_23515	ENOG410822N	TonB family
U876_23520	ENOG4109015	Biopolymer transport protein exbD tolR
U876_23540	ENOG4105VJY	transcriptional regulator
U876_23545	ENOG410600T	transposase
U876_23565	ENOG4105D05	Receptor
U876_23570	ENOG4107EV4	once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system (By similarity)
U876_23575	ENOG4105ENV	phosphonate C-P lyase system protein PhnK
U876_23580	ENOG4105FT8	Phosphonate metabolism
U876_23585	ENOG4105EKV	Phosphonate metabolism protein
U876_23605	ENOG4108W0P	ABC transporter
U876_23610	ENOG4105EHG	Permease protein
U876_23615	ENOG4105S10	periplasmic binding protein
U876_23750	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
U876_23795	ENOG4107QJE	Chromosome Partitioning Protein
U876_23865	ENOG4105K70	DNA-binding protein
U876_23930	ENOG4106A2Z	transcriptional regulator antitoxin, MazE
U876_24070	ENOG4105D8D	Type III
U876_24095	ENOG4105DIK	(ABC) transporter
U876_24120	ENOG4105CAF	HipA N-terminal domain protein
U876_24125	ENOG41061P8	Persistence to inhibition of murein or DNA biosynthesis regulatory protein
U876_24130	ENOG4108IYT	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
U876_24170	ENOG4108ZQS	transposase
U876_24175	ENOG4108MVM	Transposase
U876_24220	ENOG410600T	transposase
U876_24240	ENOG4105D05	Receptor
U876_24245	ENOG4107EV4	once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system (By similarity)
U876_24250	ENOG4105ENV	phosphonate C-P lyase system protein PhnK
U876_24255	ENOG4105FT8	Phosphonate metabolism
U876_24260	ENOG4105EKV	Phosphonate metabolism protein
U876_24280	ENOG4108W0P	ABC transporter
U876_24285	ENOG4105EHG	Permease protein
U876_24290	ENOG4105S10	periplasmic binding protein
U876_24340	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
U876_24345	ENOG410804X	Transcriptional regulator
U876_24350	ENOG4105E3W	Two component transcriptional regulator (Winged helix family
U876_24355	ENOG4105EB3	Histidine kinase
U876_24365	ENOG4105CT7	inner membrane cred family protein
U876_24370	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
U876_24375	ENOG4105KNM	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
U876_24380	ENOG4105C4J	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity)
U876_24385	ENOG4105J80	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity)
U876_24390	ENOG4105CDG	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity)
U876_24395	ENOG4107S15	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
U876_24400	ENOG4107Z6K	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
U876_24405	ENOG4105KY6	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
U876_24410	ENOG4105EE4	it plays a direct role in the translocation of protons across the membrane (By similarity)
U876_24420	ENOG4105FA0	parb-like partition protein
U876_24425	ENOG4107QJE	Chromosome Partitioning Protein
U876_24430	ENOG4105D28	Specifically methylates the N7 position of a guanine in 16S rRNA (By similarity)
U876_24435	ENOG4107RE5	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity)
U876_24440	ENOG4105QTB	Flavodoxin
U876_24445	ENOG4105E0K	tonB-dependent siderophore receptor
U876_24450	ENOG4105IBP	Cyclic peptide transporter
U876_24455	ENOG4105E0A	ABC, transporter
U876_24465	ENOG4105S6R	Iron-hydroxamate transporter permease subunit
U876_24470	ENOG4105C1H	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity)
U876_24475	ENOG4105DHW	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
U876_24480	ENOG4105NVJ	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme (By similarity)
U876_24485	ENOG4105VG0	50S ribosomal protein l34
U876_24490	ENOG4105CDA	abc transporter atp-binding protein
U876_24495	ENOG4105E5Q	amino acid AbC transporter
U876_24500	ENOG4105EAB	amino acid AbC transporter