locus-tag	class	description
IUJ49_00010	COG0812	UDP-N-acetylmuramate dehydrogenase activity
IUJ49_00015	COG0569	domain protein
IUJ49_00020	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
IUJ49_00025	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
IUJ49_00030	COG3005	denitrification pathway
IUJ49_00035	COG0243	molybdopterin cofactor binding
IUJ49_00065	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
IUJ49_00080	COG2204	response regulator
IUJ49_00090	COG2205	protein histidine kinase activity
IUJ49_00115	COG5413	integral membrane protein
IUJ49_00125	COG1522	sequence-specific DNA binding
IUJ49_00130	COG2502	aspartate--ammonia ligase
IUJ49_00135	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
IUJ49_00140	COG0542	response to heat
IUJ49_00150	COG0564	pseudouridine synthase activity
IUJ49_00155	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
IUJ49_00160	COG0446	pyridine nucleotide-disulphide oxidoreductase
IUJ49_00170	COG3681	Belongs to the UPF0597 family
IUJ49_00180	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
IUJ49_00185	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
IUJ49_00190	COG1979	alcohol dehydrogenase
IUJ49_00195	COG2207	Transcriptional regulator
IUJ49_00200	COG3040	lipid binding
IUJ49_00230	COG0688	phosphatidylethanolamine metabolic process
IUJ49_00250	COG0540	Belongs to the ATCase OTCase family
IUJ49_00255	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
IUJ49_00260	COG1438	arginine binding
IUJ49_00265	COG1288	antiporter activity
IUJ49_00270	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
IUJ49_00300	COG0840	transmembrane signaling receptor activity
IUJ49_00320	COG3250	beta-galactosidase activity
IUJ49_00325	COG1609	Transcriptional regulator
IUJ49_00330	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
IUJ49_00340	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
IUJ49_00345	COG2017	converts alpha-aldose to the beta-anomer
IUJ49_00350	COG0667	Aldo Keto reductase
IUJ49_00355	COG1968	undecaprenyl-diphosphatase activity
IUJ49_00360	COG3806	Anti-sigma factor
IUJ49_00365	COG1595	DNA-templated transcription, initiation
IUJ49_00385	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
IUJ49_00390	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
IUJ49_00395	COG0477	Major facilitator Superfamily
IUJ49_00405	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
IUJ49_00415	COG2116	formate transmembrane transporter activity
IUJ49_00420	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
IUJ49_00420	COG1648	precorrin-2 dehydrogenase activity
IUJ49_00425	COG2239	Acts as a magnesium transporter
IUJ49_00435	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
IUJ49_00440	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
IUJ49_00450	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
IUJ49_00460	COG0514	ATP-dependent DNA helicase (RecQ)
IUJ49_00465	COG2050	protein possibly involved in aromatic compounds catabolism
IUJ49_00480	COG2258	MOSC domain
IUJ49_00485	COG1177	transmembrane transport
IUJ49_00490	COG1176	ABC-type spermidine putrescine transport system, permease component I
IUJ49_00495	COG3842	ATPase activity
IUJ49_00515	COG0174	glutamine synthetase
IUJ49_00535	COG3045	CreA protein
IUJ49_00540	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
IUJ49_00545	COG0443	Heat shock 70 kDa protein
IUJ49_00560	COG0366	Alpha amylase catalytic
IUJ49_00565	COG1086	Polysaccharide biosynthesis protein
IUJ49_00570	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
IUJ49_00600	COG1215	transferase activity, transferring glycosyl groups
IUJ49_00610	COG1442	glycosyl transferase family 8
IUJ49_00615	COG1215	transferase activity, transferring glycosyl groups
IUJ49_00630	COG0318	PFAM AMP-dependent synthetase and ligase
IUJ49_00635	COG1028	Short-chain dehydrogenase reductase Sdr
IUJ49_00650	COG1083	cytidylyl-transferase
IUJ49_00660	COG2089	acid synthase
IUJ49_00680	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
IUJ49_00685	COG0745	RESPONSE REGULATOR receiver
IUJ49_00690	COG2205	protein histidine kinase activity
IUJ49_00700	COG0281	malic enzyme
IUJ49_00705	COG0702	epimerase
IUJ49_00710	COG0254	rRNA binding
IUJ49_00715	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
IUJ49_00735	COG0129	dihydroxy-acid dehydratase activity
IUJ49_00745	COG3978	acetolactate synthase activity
IUJ49_00755	COG0606	chelatase, subunit chli
IUJ49_00760	COG0204	Acyl-transferase
IUJ49_00765	COG0204	Acyl-transferase
IUJ49_00770	COG1683	Conserved Protein
IUJ49_00780	COG1335	isochorismatase
IUJ49_00790	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
IUJ49_00795	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
IUJ49_00800	COG3639	organic phosphonate transmembrane transporter activity
IUJ49_00805	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
IUJ49_00810	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
IUJ49_00820	COG3084	Protein conserved in bacteria
IUJ49_00825	COG3706	GGDEF domain
IUJ49_00825	COG2203	Gaf domain
IUJ49_00825	COG5001	Diguanylate cyclase
IUJ49_00825	COG4251	negative regulation of phosphorylation
IUJ49_00830	COG0789	Transcriptional regulator
IUJ49_00840	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
IUJ49_00845	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
IUJ49_00850	COG1561	YicC-like family, N-terminal region
IUJ49_00870	COG3306	glycosyltransferase involved in LPS biosynthesis
IUJ49_00885	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
IUJ49_00895	COG0156	8-amino-7-oxononanoate synthase activity
IUJ49_00900	COG1063	alcohol dehydrogenase
IUJ49_00905	COG3245	cytochrome
IUJ49_00915	COG0210	DNA helicase
IUJ49_00920	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
IUJ49_00925	COG2166	iron-sulfur cluster assembly
IUJ49_00930	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
IUJ49_00960	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
IUJ49_00965	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
IUJ49_00970	COG1739	Uncharacterized protein family UPF0029
IUJ49_00975	COG0006	proline dipeptidase activity
IUJ49_00980	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
IUJ49_00985	COG1024	Enoyl-CoA hydratase
IUJ49_00985	COG1250	3-hydroxyacyl-CoA dehydrogenase
IUJ49_00990	COG0183	Belongs to the thiolase family
IUJ49_01015	COG0425	Belongs to the sulfur carrier protein TusA family
IUJ49_01020	COG0251	oxidation-reduction process
IUJ49_01025	COG2885	chlorophyll binding
IUJ49_01030	COG1335	isochorismatase
IUJ49_01035	COG2818	Glycosylase
IUJ49_01040	COG0752	glycyl-tRNA synthetase alpha subunit
IUJ49_01045	COG0751	glycine-tRNA ligase activity
IUJ49_01085	COG0814	amino acid
IUJ49_01090	COG0348	domain, Protein
IUJ49_01100	COG0446	pyridine nucleotide-disulphide oxidoreductase
IUJ49_01105	COG1773	rubredoxin
IUJ49_01105	COG0426	domain, Protein
IUJ49_01110	COG3604	Transcriptional regulator
IUJ49_01115	COG1609	Transcriptional regulator
IUJ49_01155	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
IUJ49_01180	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
IUJ49_01195	COG3118	belongs to the thioredoxin family
IUJ49_01200	COG0513	Belongs to the DEAD box helicase family
IUJ49_01205	COG0248	Ppx GppA phosphatase
IUJ49_01220	COG0742	ribosomal rna small subunit methyltransferase
IUJ49_01240	COG0084	hydrolase, TatD family'
IUJ49_01245	COG0805	protein transport
IUJ49_01250	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
IUJ49_01260	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
IUJ49_01265	COG3165	ubiquinone biosynthetic process from chorismate
IUJ49_01275	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
IUJ49_01280	COG0402	S-adenosylhomocysteine deaminase activity
IUJ49_01320	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
IUJ49_01325	COG0848	biopolymer transport protein
IUJ49_01330	COG0811	peptide transport
IUJ49_01335	COG0811	peptide transport
IUJ49_01345	COG2771	luxR family
IUJ49_01350	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
IUJ49_01355	COG1349	DNA-binding transcription factor activity
IUJ49_01360	COG0745	RESPONSE REGULATOR receiver
IUJ49_01365	COG2205	protein histidine kinase activity
IUJ49_01375	COG4452	Inner membrane protein CreD
IUJ49_01380	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
IUJ49_01385	COG0355	proton-transporting ATP synthase activity, rotational mechanism
IUJ49_01390	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
IUJ49_01395	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
IUJ49_01400	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
IUJ49_01405	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
IUJ49_01410	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
IUJ49_01420	COG0356	it plays a direct role in the translocation of protons across the membrane
IUJ49_01430	COG1475	DNA binding
IUJ49_01435	COG1192	Involved in chromosome partitioning
IUJ49_01440	COG0357	Ribosomal RNA small subunit methyltransferase G
IUJ49_01445	COG0445	tRNA wobble uridine modification
IUJ49_01450	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
IUJ49_01455	COG4774	siderophore transport
IUJ49_01460	COG4615	Cyclic peptide transporter
IUJ49_01465	COG1120	ATPase activity
IUJ49_01480	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
IUJ49_01485	COG0706	membrane insertase activity
IUJ49_01490	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
IUJ49_01495	COG0594	ribonuclease P activity
IUJ49_01500	COG0230	Belongs to the bacterial ribosomal protein bL34 family
IUJ49_01505	COG1126	abc transporter atp-binding protein
IUJ49_01520	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
IUJ49_01525	COG0592	DNA-directed DNA polymerase activity
IUJ49_01545	COG2378	regulation of single-species biofilm formation
IUJ49_01550	COG0071	Belongs to the small heat shock protein (HSP20) family
IUJ49_01555	COG0071	Belongs to the small heat shock protein (HSP20) family
IUJ49_01560	COG3977	Valine--pyruvate aminotransferase
IUJ49_01575	COG2814	Major facilitator Superfamily
IUJ49_01580	COG0745	RESPONSE REGULATOR receiver
IUJ49_01585	COG2205	protein histidine kinase activity
IUJ49_01605	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
IUJ49_01610	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IUJ49_01610	COG4191	Histidine kinase
IUJ49_01615	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
IUJ49_01620	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IUJ49_01625	COG1309	transcriptional regulator
IUJ49_01655	COG0561	phosphatase activity
IUJ49_01660	COG2267	carboxylic ester hydrolase activity
IUJ49_01665	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
IUJ49_01670	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
IUJ49_01675	COG1758	RNA polymerase activity
IUJ49_01685	COG0859	PFAM glycosyl transferase family 9
IUJ49_01690	COG3642	lipopolysaccharide core region biosynthetic process
IUJ49_01730	COG0589	response to stress
IUJ49_01735	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
IUJ49_01745	COG1528	Iron-storage protein
IUJ49_01750	COG2081	HI0933 family
IUJ49_01755	COG2223	nitrite transmembrane transporter activity
IUJ49_01775	COG3188	usher protein
IUJ49_01795	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IUJ49_01795	COG2205	protein histidine kinase activity
IUJ49_01805	COG3275	phosphorelay sensor kinase activity
IUJ49_01810	COG3279	Response regulator of the LytR AlgR family
IUJ49_01815	COG2223	nitrite transmembrane transporter activity
IUJ49_01820	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
IUJ49_01825	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
IUJ49_01840	COG0583	DNA-binding transcription factor activity
IUJ49_01845	COG4206	TonB-dependent receptor
IUJ49_01850	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
IUJ49_01900	COG0583	DNA-binding transcription factor activity
IUJ49_01905	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
IUJ49_01910	COG0166	Belongs to the GPI family
IUJ49_01920	COG0668	transmembrane transport
IUJ49_01925	COG1309	transcriptional regulator
IUJ49_01930	COG0756	dUTP diphosphatase activity
IUJ49_01935	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
IUJ49_01940	COG2003	Belongs to the UPF0758 family
IUJ49_01945	COG0227	Belongs to the bacterial ribosomal protein bL28 family
IUJ49_01950	COG0267	Belongs to the bacterial ribosomal protein bL33 family
IUJ49_01960	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
IUJ49_01965	COG2990	Protein conserved in bacteria
IUJ49_01970	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
IUJ49_01975	COG0859	PFAM glycosyl transferase family 9
IUJ49_01980	COG0463	Glycosyl transferase, family 2
IUJ49_01985	COG0859	PFAM glycosyl transferase family 9
IUJ49_01990	COG1519	Transferase
IUJ49_02010	COG1609	Transcriptional regulator
IUJ49_02015	COG0604	alcohol dehydrogenase
IUJ49_02030	COG1580	Controls the rotational direction of flagella during chemotaxis
IUJ49_02035	COG3161	chorismate lyase activity
IUJ49_02040	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
IUJ49_02045	COG2937	Belongs to the GPAT DAPAT family
IUJ49_02050	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
IUJ49_02065	COG0534	Mate efflux family protein
IUJ49_02070	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
IUJ49_02075	COG2205	protein histidine kinase activity
IUJ49_02080	COG0745	RESPONSE REGULATOR receiver
IUJ49_02090	COG1045	serine acetyltransferase
IUJ49_02100	COG3074	FtsZ-dependent cytokinesis
IUJ49_02105	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
IUJ49_02110	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
IUJ49_02110	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
IUJ49_02115	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
IUJ49_02150	COG1609	Transcriptional regulator
IUJ49_02155	COG3250	beta-galactosidase activity
IUJ49_02160	COG2731	YhcH YjgK YiaL family protein
IUJ49_02165	COG0531	amino acid
IUJ49_02170	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
IUJ49_02175	COG0531	amino acid
IUJ49_02180	COG0385	Bile acid
IUJ49_02185	COG1262	PFAM Formylglycine-generating sulfatase enzyme
IUJ49_02205	COG0583	DNA-binding transcription factor activity
IUJ49_02210	COG1079	Belongs to the binding-protein-dependent transport system permease family
IUJ49_02215	COG4603	Belongs to the binding-protein-dependent transport system permease family
IUJ49_02220	COG3845	ABC transporter
IUJ49_02225	COG1744	ABC transporter substrate-binding protein PnrA-like
IUJ49_02230	COG0210	DNA helicase
IUJ49_02245	COG1943	Transposase
IUJ49_02250	COG0583	DNA-binding transcription factor activity
IUJ49_02305	COG1280	lysine exporter protein (LysE YggA)
IUJ49_02310	COG2391	methyltransferase activity
IUJ49_02320	COG1280	lysine exporter protein (LysE YggA)
IUJ49_02330	COG2962	Rard protein
IUJ49_02340	COG1012	belongs to the aldehyde dehydrogenase family
IUJ49_02345	COG1396	sequence-specific DNA binding
IUJ49_02350	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
IUJ49_02360	COG0518	GMP synthase (glutamine-hydrolyzing) activity
IUJ49_02360	COG0519	Catalyzes the synthesis of GMP from XMP
IUJ49_02365	COG0686	Belongs to the AlaDH PNT family
IUJ49_02370	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IUJ49_02390	COG1322	Protein conserved in bacteria
IUJ49_02395	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
IUJ49_02400	COG0569	domain protein
IUJ49_02405	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
IUJ49_02405	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
IUJ49_02410	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
IUJ49_02415	COG0242	peptide deformylase activity
IUJ49_02425	COG0758	DNA mediated transformation
IUJ49_02430	COG2922	Belongs to the Smg family
IUJ49_02435	COG0551	DNA topoisomerase type I activity
IUJ49_02445	COG0009	L-threonylcarbamoyladenylate synthase
IUJ49_02450	COG0408	coproporphyrinogen oxidase activity
IUJ49_02455	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
IUJ49_02465	COG0218	Necessary for normal cell division and for the maintenance of normal septation
IUJ49_02475	COG3078	GTPase activator activity
IUJ49_02485	COG0635	Involved in the biosynthesis of porphyrin-containing compound
IUJ49_02490	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
IUJ49_02495	COG2204	response regulator
IUJ49_02500	COG3852	Histidine kinase
IUJ49_02510	COG0174	glutamine synthetase
IUJ49_02515	COG1217	gtp-binding protein TYPA
IUJ49_02520	COG1295	ribonuclease BN
IUJ49_02525	COG1490	D-aminoacyl-tRNA deacylase activity
IUJ49_02535	COG0456	acetyltransferase
IUJ49_02545	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
IUJ49_02550	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
IUJ49_02555	COG2610	gluconate transmembrane transporter activity
IUJ49_02560	COG3265	gluconokinase activity
IUJ49_02570	COG0800	Aldolase
IUJ49_02575	COG1609	Transcriptional regulator
IUJ49_02585	COG4942	peptidase
IUJ49_02590	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
IUJ49_02595	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
IUJ49_02600	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
IUJ49_02605	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
IUJ49_02610	COG0316	Belongs to the HesB IscA family
IUJ49_02610	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
IUJ49_02615	COG1040	competence protein
IUJ49_02620	COG0596	Alpha beta hydrolase
IUJ49_02640	COG2183	response to ionizing radiation
IUJ49_02645	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
IUJ49_02665	COG0051	transcription antitermination factor activity, RNA binding
IUJ49_02670	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
IUJ49_02675	COG0088	Forms part of the polypeptide exit tunnel
IUJ49_02680	COG0089	rRNA binding
IUJ49_02685	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
IUJ49_02690	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
IUJ49_02695	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
IUJ49_02700	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
IUJ49_02705	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
IUJ49_02710	COG0255	Belongs to the universal ribosomal protein uL29 family
IUJ49_02715	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
IUJ49_02720	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
IUJ49_02725	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
IUJ49_02730	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
IUJ49_02735	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
IUJ49_02740	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
IUJ49_02745	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
IUJ49_02750	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
IUJ49_02755	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
IUJ49_02760	COG1841	ribosomal large subunit assembly
IUJ49_02765	COG0200	Binds to the 23S rRNA
IUJ49_02770	COG0201	protein transport
IUJ49_02775	COG0257	Belongs to the bacterial ribosomal protein bL36 family
IUJ49_02780	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
IUJ49_02785	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
IUJ49_02790	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
IUJ49_02795	COG0202	RNA polymerase activity
IUJ49_02800	COG0203	ribosomal protein L17
IUJ49_02855	COG2249	NAD(P)H dehydrogenase (quinone) activity
IUJ49_02860	COG0583	DNA-binding transcription factor activity
IUJ49_02865	COG4221	oxidoreductase activity
IUJ49_02880	COG1770	oligopeptidase
IUJ49_02900	COG3714	YhhN family
IUJ49_02925	COG1301	dicarboxylic acid transport
IUJ49_02935	COG2095	MarC family integral membrane protein
IUJ49_02945	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
IUJ49_02955	COG0741	lytic transglycosylase activity
IUJ49_02965	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
IUJ49_02990	COG0742	ribosomal rna small subunit methyltransferase
IUJ49_02995	COG0552	protein localization to endoplasmic reticulum
IUJ49_03000	COG2884	Cell division ATP-binding protein ftsE
IUJ49_03005	COG2177	Part of the ABC transporter FtsEX involved in
IUJ49_03015	COG0288	reversible hydration of carbon dioxide
IUJ49_03020	COG2188	Transcriptional regulator
IUJ49_03025	COG1228	amidohydrolase
IUJ49_03030	COG0010	Belongs to the arginase family
IUJ49_03035	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
IUJ49_03040	COG2986	histidine ammonia-lyase
IUJ49_03045	COG0387	Pfam Sodium calcium exchanger
IUJ49_03050	COG2200	EAL domain
IUJ49_03055	COG2200	EAL domain
IUJ49_03055	COG2199	diguanylate cyclase activity
IUJ49_03100	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
IUJ49_03105	COG1459	type II secretion system
IUJ49_03115	COG2165	general secretion pathway protein
IUJ49_03125	COG4968	Prepilin-type N-terminal cleavage methylation domain
IUJ49_03150	COG1077	Cell shape determining protein MreB Mrl
IUJ49_03155	COG1792	Involved in formation and maintenance of cell shape
IUJ49_03160	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
IUJ49_03165	COG0424	maF-like protein
IUJ49_03170	COG1530	ribonuclease E activity
IUJ49_03175	COG3164	Protein of unknown function
IUJ49_03185	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
IUJ49_03190	COG0312	modulator of DNA gyrase
IUJ49_03210	COG1263	PTS System
IUJ49_03210	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
IUJ49_03215	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
IUJ49_03235	COG0477	Major facilitator Superfamily
IUJ49_03245	COG3437	response regulator, receiver
IUJ49_03250	COG0784	Response regulator, receiver
IUJ49_03250	COG2205	protein histidine kinase activity
IUJ49_03250	COG5002	protein histidine kinase activity
IUJ49_03255	COG2172	sigma factor antagonist activity
IUJ49_03260	COG1366	Belongs to the anti-sigma-factor antagonist family
IUJ49_03280	COG3700	Belongs to the class B bacterial acid phosphatase family
IUJ49_03285	COG2321	neutral zinc metallopeptidase
IUJ49_03295	COG1639	'signal transduction protein
IUJ49_03320	COG0189	ligase activity
IUJ49_03330	COG0642	Histidine kinase
IUJ49_03335	COG0745	RESPONSE REGULATOR receiver
IUJ49_03355	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
IUJ49_03360	COG0352	thiamine-phosphate diphosphorylase activity
IUJ49_03365	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
IUJ49_03375	COG2022	thiamine diphosphate biosynthetic process
IUJ49_03380	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
IUJ49_03395	COG3417	Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1B (PBP1b)
IUJ49_03410	COG3706	GGDEF domain
IUJ49_03415	COG0814	amino acid
IUJ49_03420	COG3932	Exopolysaccharide synthesis, ExoD
IUJ49_03480	COG1494	fructose-1,6-bisphosphatase
IUJ49_03495	COG2959	enzyme of heme biosynthesis
IUJ49_03505	COG0181	hydroxymethylbilane synthase activity
IUJ49_03510	COG3072	Adenylate cyclase
IUJ49_03515	COG0400	carboxylic ester hydrolase activity
IUJ49_03520	COG1965	Belongs to the frataxin family
IUJ49_03530	COG0019	diaminopimelate decarboxylase activity
IUJ49_03535	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
IUJ49_03550	COG1011	Hydrolase
IUJ49_03570	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
IUJ49_03575	COG0561	phosphatase activity
IUJ49_03590	COG0842	Transport permease protein
IUJ49_03590	COG1129	ABC transporter
IUJ49_03600	COG1546	Belongs to the CinA family
IUJ49_03600	COG1058	Belongs to the CinA family
IUJ49_03605	COG1418	mRNA catabolic process
IUJ49_03610	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
IUJ49_03620	COG1522	sequence-specific DNA binding
IUJ49_03625	COG1368	sulfuric ester hydrolase activity
IUJ49_03645	COG1285	pathogenesis
IUJ49_03665	COG4221	oxidoreductase activity
IUJ49_03685	COG1979	alcohol dehydrogenase
IUJ49_03695	COG2873	o-acetylhomoserine
IUJ49_03705	COG4533	DNA binding
IUJ49_03720	COG5380	lipid catabolic process
IUJ49_03725	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
IUJ49_03735	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
IUJ49_03740	COG2949	membrane
IUJ49_03745	COG3291	Pkd domain containing protein
IUJ49_03755	COG3539	Fimbrial protein
IUJ49_03765	COG3188	usher protein
IUJ49_03770	COG3121	Chaperone
IUJ49_03775	COG3539	Fimbrial protein
IUJ49_03790	COG0318	PFAM AMP-dependent synthetase and ligase
IUJ49_03795	COG1441	menaquinone biosynthetic process
IUJ49_03800	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
IUJ49_03805	COG0596	Alpha beta hydrolase
IUJ49_03810	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
IUJ49_03815	COG1169	isochorismate synthase
IUJ49_03820	COG1575	Belongs to the MenA family. Type 1 subfamily
IUJ49_03845	COG0513	Belongs to the DEAD box helicase family
IUJ49_03850	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
IUJ49_03855	COG1988	membrane-bound metal-dependent
IUJ49_03870	COG1671	Belongs to the UPF0178 family
IUJ49_03895	COG3263	regulation of cellular component size
IUJ49_03900	COG3722	fumarate hydratase activity
IUJ49_03905	COG0246	Mannitol dehydrogenase
IUJ49_03910	COG2213	PTS system mannitol-specific
IUJ49_03910	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
IUJ49_03920	COG1309	transcriptional regulator
IUJ49_03925	COG4776	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction
IUJ49_03935	COG3916	Acyl-homoserine-lactone synthase
IUJ49_03940	COG2771	luxR family
IUJ49_03955	COG3133	Outer membrane lipoprotein
IUJ49_03960	COG0456	acetyltransferase
IUJ49_03980	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
IUJ49_03985	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
IUJ49_03995	COG3031	protein transport across the cell outer membrane
IUJ49_04005	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
IUJ49_04010	COG1459	type II secretion system
IUJ49_04015	COG2165	general secretion pathway protein
IUJ49_04025	COG2165	general secretion pathway protein
IUJ49_04030	COG4795	General secretion pathway protein
IUJ49_04040	COG3156	type II secretion system protein K
IUJ49_04050	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
IUJ49_04065	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
IUJ49_04070	COG1011	Hydrolase
IUJ49_04075	COG0494	nUDIX hydrolase
IUJ49_04080	COG1218	3'(2'),5'-bisphosphate nucleotidase
IUJ49_04085	COG0814	amino acid
IUJ49_04090	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
IUJ49_04095	COG2207	Transcriptional regulator
IUJ49_04095	COG3708	Transcriptional regulator
IUJ49_04105	COG0626	cystathionine gamma-synthase activity
IUJ49_04110	COG0460	homoserine dehydrogenase
IUJ49_04110	COG0527	aspartate kinase activity
IUJ49_04115	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
IUJ49_04125	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
IUJ49_04130	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
IUJ49_04140	COG0137	argininosuccinate synthase activity
IUJ49_04145	COG0165	Argininosuccinate lyase
IUJ49_04175	COG0110	maltose O-acetyltransferase activity
IUJ49_04180	COG3174	membrane
IUJ49_04185	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
IUJ49_04195	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
IUJ49_04200	COG4208	sulfate ABC transporter
IUJ49_04205	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
IUJ49_04210	COG0583	DNA-binding transcription factor activity
IUJ49_04215	COG3397	chitin binding
IUJ49_04220	COG0840	transmembrane signaling receptor activity
IUJ49_04245	COG0793	Belongs to the peptidase S41A family
IUJ49_04245	COG4946	Tricorn protease homolog
IUJ49_04265	COG1328	CTP reductase activity
IUJ49_04270	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
IUJ49_04285	COG1448	Aminotransferase
IUJ49_04325	COG0513	Belongs to the DEAD box helicase family
IUJ49_04345	COG0840	transmembrane signaling receptor activity
IUJ49_04360	COG3112	Uncharacterised protein family (UPF0231)
IUJ49_04365	COG3835	regulator
IUJ49_04370	COG2610	gluconate transmembrane transporter activity
IUJ49_04375	COG1929	Belongs to the glycerate kinase type-1 family
IUJ49_04390	COG0583	DNA-binding transcription factor activity
IUJ49_04395	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
IUJ49_04410	COG0347	Belongs to the P(II) protein family
IUJ49_04415	COG1840	ABC-type Fe3 transport system, periplasmic component
IUJ49_04425	COG3842	ATPase activity
IUJ49_04430	COG2837	iron assimilation
IUJ49_04435	COG1438	arginine binding
IUJ49_04440	COG1126	abc transporter atp-binding protein
IUJ49_04445	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IUJ49_04450	COG4215	(ABC) transporter
IUJ49_04455	COG4160	amino acid transport
IUJ49_04460	COG0039	L-malate dehydrogenase activity
IUJ49_04465	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
IUJ49_04470	COG1017	nitric oxide dioxygenase activity
IUJ49_04470	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
IUJ49_04480	COG4536	flavin adenine dinucleotide binding
IUJ49_04485	COG4137	Cytochrome C assembly protein
IUJ49_04490	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
IUJ49_04495	COG0228	four-way junction DNA binding
IUJ49_04500	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
IUJ49_04505	COG0336	Belongs to the RNA methyltransferase TrmD family
IUJ49_04510	COG0335	large ribosomal subunit rRNA binding
IUJ49_04520	COG3066	DNA modification
IUJ49_04525	COG1051	belongs to the nudix hydrolase family
IUJ49_04535	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
IUJ49_04540	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
IUJ49_04545	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
IUJ49_04555	COG0583	DNA-binding transcription factor activity
IUJ49_04560	COG0640	Transcriptional regulator
IUJ49_04565	COG0268	Binds directly to 16S ribosomal RNA
IUJ49_04570	COG0728	peptidoglycan biosynthetic process
IUJ49_04580	COG0196	riboflavin kinase activity
IUJ49_04585	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
IUJ49_04590	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
IUJ49_04595	COG1047	Peptidyl-prolyl cis-trans
IUJ49_04600	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
IUJ49_04605	COG4970	Tfp pilus assembly protein FimT
IUJ49_04660	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
IUJ49_04660	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
IUJ49_04675	COG1854	S-ribosylhomocysteine lyase activity
IUJ49_04680	COG3706	GGDEF domain
IUJ49_04685	COG0557	exoribonuclease II activity
IUJ49_04690	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
IUJ49_04700	COG2153	protein acetylation
IUJ49_04720	COG1914	H( )-stimulated, divalent metal cation uptake system
IUJ49_04725	COG0360	Binds together with S18 to 16S ribosomal RNA
IUJ49_04730	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
IUJ49_04735	COG0359	binds to the 23S rRNA
IUJ49_04740	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
IUJ49_04765	COG1238	metal cluster binding
IUJ49_04770	COG0612	Peptidase, M16
IUJ49_04775	COG2918	glutathione biosynthetic process
IUJ49_04780	COG1022	Amp-dependent synthetase and ligase
IUJ49_04790	COG0456	acetyltransferase
IUJ49_04800	COG0714	Associated with various cellular activities
IUJ49_04845	COG1902	pentaerythritol trinitrate reductase activity
IUJ49_04860	COG2957	Belongs to the agmatine deiminase family
IUJ49_04865	COG0154	amidase activity
IUJ49_04905	COG0513	Belongs to the DEAD box helicase family
IUJ49_04945	COG1912	Pfam S-adenosyl-l-methionine hydroxide adenosyltransferase
IUJ49_04950	COG1858	cytochrome C peroxidase
IUJ49_04975	COG2070	2-Nitropropane dioxygenase
IUJ49_05005	COG2816	NAD+ diphosphatase activity
IUJ49_05010	COG2205	protein histidine kinase activity
IUJ49_05015	COG0745	RESPONSE REGULATOR receiver
IUJ49_05020	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IUJ49_05025	COG0577	efflux transmembrane transporter activity
IUJ49_05025	COG1136	(ABC) transporter
IUJ49_05030	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IUJ49_05035	COG1126	abc transporter atp-binding protein
IUJ49_05045	COG0765	amino acid transport
IUJ49_05050	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
IUJ49_05055	COG1505	serine-type exopeptidase activity
IUJ49_05070	COG1028	Short-chain dehydrogenase reductase Sdr
IUJ49_05075	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
IUJ49_05090	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
IUJ49_05095	COG4991	sh3 domain protein
IUJ49_05110	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
IUJ49_05115	COG1940	carbohydrate kinase activity
IUJ49_05120	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
IUJ49_05125	COG0126	phosphoglycerate kinase activity
IUJ49_05135	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
IUJ49_05150	COG1324	tolerance protein
IUJ49_05175	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
IUJ49_05185	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
IUJ49_05190	COG1595	DNA-templated transcription, initiation
IUJ49_05195	COG3073	An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E
IUJ49_05210	COG0481	GTPase activity
IUJ49_05215	COG0681	Belongs to the peptidase S26 family
IUJ49_05220	COG0571	ribonuclease III activity
IUJ49_05230	COG1381	Involved in DNA repair and RecF pathway recombination
IUJ49_05235	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
IUJ49_05250	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
IUJ49_05255	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
IUJ49_05260	COG3716	PTS system mannose fructose sorbose family IID component
IUJ49_05270	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
IUJ49_05275	COG2222	sugar isomerase
IUJ49_05285	COG1349	DNA-binding transcription factor activity
IUJ49_05290	COG3023	N-Acetylmuramoyl-L-alanine amidase
IUJ49_05295	COG4807	Protein conserved in bacteria
IUJ49_05305	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
IUJ49_05310	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
IUJ49_05315	COG3956	TIGRFAM MazG family protein
IUJ49_05320	COG0504	CTP synthase activity
IUJ49_05325	COG0148	phosphopyruvate hydratase activity
IUJ49_05330	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
IUJ49_05335	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
IUJ49_05345	COG0585	pseudouridine synthase activity
IUJ49_05350	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
IUJ49_05355	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
IUJ49_05360	COG1238	metal cluster binding
IUJ49_05375	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
IUJ49_05380	COG0828	Belongs to the bacterial ribosomal protein bS21 family
IUJ49_05385	COG1610	YqeY-like protein
IUJ49_05390	COG0358	DNA primase activity
IUJ49_05395	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
IUJ49_05420	COG0151	Belongs to the GarS family
IUJ49_05425	COG0138	bifunctional purine biosynthesis protein purh
IUJ49_05435	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
IUJ49_05440	COG3036	rescue of stalled ribosome
IUJ49_05445	COG0635	Involved in the biosynthesis of porphyrin-containing compound
IUJ49_05450	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
IUJ49_05460	COG0673	inositol 2-dehydrogenase activity
IUJ49_05470	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
IUJ49_05475	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
IUJ49_05480	COG3227	Zinc metalloprotease (Elastase)
IUJ49_05490	COG0477	Major facilitator Superfamily
IUJ49_05500	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
IUJ49_05505	COG1027	Aspartate ammonia-lyase
IUJ49_05510	COG3030	protein affecting phage T7 exclusion by the F plasmid
IUJ49_05515	COG0534	Mate efflux family protein
IUJ49_05520	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
IUJ49_05525	COG0459	protein refolding
IUJ49_05535	COG3300	MHYT domain
IUJ49_05535	COG5001	Diguanylate cyclase
IUJ49_05545	COG0564	pseudouridine synthase activity
IUJ49_05550	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
IUJ49_05575	COG1280	lysine exporter protein (LysE YggA)
IUJ49_05580	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
IUJ49_05595	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IUJ49_05625	COG0745	RESPONSE REGULATOR receiver
IUJ49_05630	COG3104	oligopeptide transport
IUJ49_05635	COG1210	Utp--glucose-1-phosphate uridylyltransferase
IUJ49_05640	COG1555	photosystem II stabilization
IUJ49_05650	COG2350	Protein conserved in bacteria
IUJ49_05655	COG2917	probably involved in intracellular septation
IUJ49_05660	COG0076	glutamate decarboxylase activity
IUJ49_05665	COG1272	protein, Hemolysin III
IUJ49_05670	COG0569	domain protein
IUJ49_05670	COG2985	domain, Protein
IUJ49_05680	COG0784	Response regulator, receiver
IUJ49_05680	COG0835	chemotaxis
IUJ49_05685	COG2755	lipolytic protein G-D-S-L family
IUJ49_05690	COG4181	ATPase activity
IUJ49_05695	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
IUJ49_05700	COG1090	epimerase
IUJ49_05705	COG2200	EAL domain
IUJ49_05710	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
IUJ49_05715	COG2234	aminopeptidase activity
IUJ49_05715	COG4935	Belongs to the peptidase S8 family
IUJ49_05720	COG0220	tRNA (guanine-N7-)-methyltransferase activity
IUJ49_05725	COG3171	Protein conserved in bacteria
IUJ49_05730	COG2066	Belongs to the glutaminase family
IUJ49_05735	COG2897	thiosulfate sulfurtransferase activity
IUJ49_05740	COG1404	Belongs to the peptidase S8 family
IUJ49_05750	COG1132	(ABC) transporter
IUJ49_05775	COG3076	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome
IUJ49_05780	COG5001	Diguanylate cyclase
IUJ49_05780	COG3300	MHYT domain
IUJ49_05790	COG2207	Transcriptional regulator
IUJ49_05795	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
IUJ49_05800	COG3059	membrane
IUJ49_05815	COG4628	conserved protein (DUF2132)
IUJ49_05820	COG0688	phosphatidylethanolamine metabolic process
IUJ49_05825	COG1162	GTPase activity
IUJ49_05830	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
IUJ49_05870	COG1278	Cold shock
IUJ49_05880	COG0840	transmembrane signaling receptor activity
IUJ49_05885	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
IUJ49_05890	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
IUJ49_05900	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
IUJ49_05950	COG0848	biopolymer transport protein
IUJ49_05955	COG0811	peptide transport
IUJ49_05960	COG0811	peptide transport
IUJ49_05975	COG4174	ABC transporter (Permease)
IUJ49_05980	COG4239	(ABC) transporter, permease
IUJ49_05990	COG0444	Belongs to the ABC transporter superfamily
IUJ49_05995	COG4608	Belongs to the ABC transporter superfamily
IUJ49_06000	COG2195	Cleaves the N-terminal amino acid of tripeptides
IUJ49_06005	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
IUJ49_06010	COG1073	alpha beta
IUJ49_06025	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
IUJ49_06055	COG0243	molybdopterin cofactor binding
IUJ49_06070	COG1116	anion transmembrane transporter activity
IUJ49_06070	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
IUJ49_06075	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
IUJ49_06080	COG1116	anion transmembrane transporter activity
IUJ49_06085	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
IUJ49_06085	COG2146	nitrite reductase [NAD(P)H] activity
IUJ49_06090	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
IUJ49_06090	COG2146	nitrite reductase [NAD(P)H] activity
IUJ49_06095	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IUJ49_06100	COG2313	pseudouridylate synthase activity
IUJ49_06105	COG2313	pseudouridylate synthase activity
IUJ49_06115	COG1858	cytochrome C peroxidase
IUJ49_06150	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
IUJ49_06155	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
IUJ49_06205	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
IUJ49_06215	COG1028	Short-chain dehydrogenase reductase Sdr
IUJ49_06230	COG0521	Mo-molybdopterin cofactor biosynthetic process
IUJ49_06240	COG2966	Psort location CytoplasmicMembrane, score
IUJ49_06245	COG3610	response to peptide
IUJ49_06255	COG4175	Glycine betaine
IUJ49_06260	COG4176	ABC-type proline glycine betaine transport system permease component
IUJ49_06265	COG2113	Glycine betaine
IUJ49_06270	COG0175	sulfate reduction
IUJ49_06275	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
IUJ49_06280	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
IUJ49_06285	COG0384	phenazine biosynthesis protein PhzF
IUJ49_06290	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
IUJ49_06305	COG0786	glutamate:sodium symporter activity
IUJ49_06310	COG0252	asparaginase activity
IUJ49_06315	COG3139	Protein of unknown function (DUF1315)
IUJ49_06335	COG0616	signal peptide processing
IUJ49_06340	COG0446	pyridine nucleotide-disulphide oxidoreductase
IUJ49_06340	COG1902	pentaerythritol trinitrate reductase activity
IUJ49_06345	COG0778	Nitroreductase
IUJ49_06360	COG2264	protein methyltransferase activity
IUJ49_06365	COG0604	alcohol dehydrogenase
IUJ49_06370	COG0583	DNA-binding transcription factor activity
IUJ49_06375	COG2190	(PTS) system
IUJ49_06375	COG1263	PTS System
IUJ49_06375	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
IUJ49_06380	COG4145	pantothenate transmembrane transporter activity
IUJ49_06390	COG0439	Biotin carboxylase
IUJ49_06395	COG0511	ligase activity, forming carbon-carbon bonds
IUJ49_06400	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
IUJ49_06405	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
IUJ49_06415	COG3300	MHYT domain
IUJ49_06415	COG5001	Diguanylate cyclase
IUJ49_06435	COG3381	protein complex oligomerization
IUJ49_06450	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
IUJ49_06465	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
IUJ49_06470	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
IUJ49_06470	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
IUJ49_06490	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
IUJ49_06495	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
IUJ49_06500	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
IUJ49_06505	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
IUJ49_06510	COG4172	Belongs to the ABC transporter superfamily
IUJ49_06520	COG0601	transmembrane transport
IUJ49_06530	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
IUJ49_06535	COG0142	geranyltranstransferase activity
IUJ49_06540	COG1722	exodeoxyribonuclease VII activity
IUJ49_06545	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
IUJ49_06550	COG1360	Flagellar Motor Protein
IUJ49_06565	COG1534	Rna-binding protein
IUJ49_06570	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
IUJ49_06580	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
IUJ49_06585	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
IUJ49_06590	COG0149	triose-phosphate isomerase activity
IUJ49_06595	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
IUJ49_06610	COG0779	Required for maturation of 30S ribosomal subunits
IUJ49_06615	COG0195	Participates in both transcription termination and antitermination
IUJ49_06620	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
IUJ49_06625	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
IUJ49_06630	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
IUJ49_06635	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
IUJ49_06640	COG1185	polyribonucleotide nucleotidyltransferase activity
IUJ49_06645	COG2211	Major facilitator Superfamily
IUJ49_06650	COG3706	GGDEF domain
IUJ49_06655	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
IUJ49_06665	COG0114	fumarate hydratase activity
IUJ49_06675	COG1966	Carbon starvation protein
IUJ49_06680	COG3279	Response regulator of the LytR AlgR family
IUJ49_06685	COG3275	phosphorelay sensor kinase activity
IUJ49_06750	COG0312	modulator of DNA gyrase
IUJ49_06755	COG0312	modulator of DNA gyrase
IUJ49_06765	COG4974	Belongs to the 'phage' integrase family
IUJ49_06770	COG1970	mechanosensitive ion channel activity
IUJ49_06775	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
IUJ49_06785	COG0789	Transcriptional regulator
IUJ49_06800	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
IUJ49_06805	COG3545	Serine hydrolase
IUJ49_06815	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
IUJ49_06820	COG0321	lipoyl(octanoyl) transferase activity
IUJ49_06825	COG2921	Belongs to the UPF0250 family
IUJ49_06830	COG1686	Belongs to the peptidase S11 family
IUJ49_06835	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
IUJ49_06840	COG2951	lytic endotransglycosylase activity
IUJ49_06845	COG0772	Belongs to the SEDS family
IUJ49_06850	COG0772	Belongs to the SEDS family
IUJ49_06855	COG0768	penicillin binding
IUJ49_06860	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
IUJ49_06865	COG0799	negative regulation of ribosome biogenesis
IUJ49_06870	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
IUJ49_06890	COG0495	leucyl-tRNA aminoacylation
IUJ49_06895	COG2888	peptidyl-tyrosine sulfation
IUJ49_06900	COG0815	Transfers the fatty acyl group on membrane lipoproteins
IUJ49_06905	COG4535	Mg2 and Co2 transporter CorC
IUJ49_06910	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
IUJ49_06915	COG1702	phosphate starvation-inducible protein PhoH
IUJ49_06925	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
IUJ49_06930	COG1335	isochorismatase
IUJ49_06940	COG3706	GGDEF domain
IUJ49_06945	COG0583	DNA-binding transcription factor activity
IUJ49_06955	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
IUJ49_06975	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
IUJ49_06985	COG3647	Membrane
IUJ49_06990	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
IUJ49_07000	COG0516	GMP reductase activity
IUJ49_07020	COG0642	Histidine kinase
IUJ49_07060	COG3214	Protein conserved in bacteria
IUJ49_07085	COG3029	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
IUJ49_07090	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
IUJ49_07095	COG1053	succinate dehydrogenase
IUJ49_07105	COG0584	glycerophosphoryl diester phosphodiesterase
IUJ49_07110	COG1511	domain protein
IUJ49_07110	COG3264	Mechanosensitive ion channel
IUJ49_07120	COG0739	heme binding
IUJ49_07135	COG0583	DNA-binding transcription factor activity
IUJ49_07155	COG0583	DNA-binding transcription factor activity
IUJ49_07160	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
IUJ49_07190	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
IUJ49_07195	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
IUJ49_07205	COG0338	D12 class N6 adenine-specific DNA methyltransferase
IUJ49_07210	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
IUJ49_07220	COG0180	Tryptophanyl-tRNA synthetase
IUJ49_07235	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
IUJ49_07245	COG1012	belongs to the aldehyde dehydrogenase family
IUJ49_07255	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
IUJ49_07265	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
IUJ49_07265	COG1013	pyruvate-flavodoxin oxidoreductase activity
IUJ49_07265	COG0674	pyruvate-flavodoxin oxidoreductase activity
IUJ49_07265	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
IUJ49_07275	COG0366	Alpha amylase catalytic
IUJ49_07285	COG3097	Belongs to the UPF0267 family
IUJ49_07295	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
IUJ49_07305	COG0490	domain, Protein
IUJ49_07305	COG0471	metal ion transport
IUJ49_07350	COG0012	GTP binding
IUJ49_07355	COG0193	aminoacyl-tRNA hydrolase activity
IUJ49_07360	COG0737	Belongs to the 5'-nucleotidase family
IUJ49_07365	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
IUJ49_07375	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
IUJ49_07380	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
IUJ49_07385	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
IUJ49_07390	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
IUJ49_07395	COG2890	protein-(glutamine-N5) methyltransferase activity
IUJ49_07405	COG2912	Transglutaminase-like superfamily
IUJ49_07410	COG2877	3-deoxy-8-phosphooctulonate synthase activity
IUJ49_07415	COG1301	dicarboxylic acid transport
IUJ49_07425	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
IUJ49_07440	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
IUJ49_07445	COG1115	amino acid carrier protein
IUJ49_07460	COG0714	Associated with various cellular activities
IUJ49_07470	COG3104	oligopeptide transport
IUJ49_07475	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
IUJ49_07480	COG1678	Uncharacterized ACR, COG1678
IUJ49_07490	COG0189	ligase activity
IUJ49_07495	COG1385	rRNA (uridine-N3-)-methyltransferase activity
IUJ49_07505	COG3091	SprT-like family
IUJ49_07515	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
IUJ49_07535	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
IUJ49_07540	COG0739	heme binding
IUJ49_07545	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
IUJ49_07550	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
IUJ49_07550	COG3408	Glycogen debranching enzyme
IUJ49_07560	COG1881	PFAM PEBP family protein
IUJ49_07565	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
IUJ49_07570	COG0583	DNA-binding transcription factor activity
IUJ49_07580	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
IUJ49_07590	COG0583	DNA-binding transcription factor activity
IUJ49_07595	COG1028	Short-chain dehydrogenase reductase Sdr
IUJ49_07600	COG0616	signal peptide processing
IUJ49_07605	COG3724	N-succinylarginine dihydrolase activity
IUJ49_07625	COG0840	transmembrane signaling receptor activity
IUJ49_07635	COG2971	BadF BadG BcrA BcrD
IUJ49_07645	COG4608	Belongs to the ABC transporter superfamily
IUJ49_07650	COG0444	Belongs to the ABC transporter superfamily
IUJ49_07655	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
IUJ49_07660	COG0601	transmembrane transport
IUJ49_07665	COG4166	transmembrane transport
IUJ49_07670	COG0784	Response regulator, receiver
IUJ49_07670	COG2205	protein histidine kinase activity
IUJ49_07700	COG3220	belongs to the UPF0276 family
IUJ49_07730	COG1289	transmembrane transporter activity
IUJ49_07735	COG0303	'Molybdopterin
IUJ49_07740	COG0746	molybdenum cofactor guanylyltransferase activity
IUJ49_07750	COG4662	Binding-protein-dependent transport system inner membrane component
IUJ49_07760	COG2204	response regulator
IUJ49_07765	COG3852	Histidine kinase
IUJ49_07770	COG1910	domain protein
IUJ49_07775	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
IUJ49_07810	COG3383	formate dehydrogenase (NAD+) activity
IUJ49_07810	COG3383	formate dehydrogenase (NAD+) activity
IUJ49_07815	COG0437	4 iron, 4 sulfur cluster binding
IUJ49_07830	COG0281	malic enzyme
IUJ49_07840	COG2706	6-phosphogluconolactonase activity
IUJ49_07850	COG1196	nuclear chromosome segregation
IUJ49_07850	COG3264	Mechanosensitive ion channel
IUJ49_07855	COG0469	pyruvate kinase activity
IUJ49_07870	COG4651	solute:proton antiporter activity
IUJ49_07870	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
IUJ49_07880	COG2974	May be involved in recombination
IUJ49_07890	COG0420	3'-5' exonuclease activity
IUJ49_07895	COG0419	ATPase involved in DNA repair
IUJ49_07910	COG3038	cytochrome b561
IUJ49_07925	COG2190	(PTS) system
IUJ49_07935	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
IUJ49_07940	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
IUJ49_07945	COG0542	response to heat
IUJ49_07960	COG1720	tRNA m6t6A37 methyltransferase activity
IUJ49_07980	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
IUJ49_07985	COG4988	ABC transporter
IUJ49_08000	COG0745	RESPONSE REGULATOR receiver
IUJ49_08010	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
IUJ49_08025	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
IUJ49_08030	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
IUJ49_08040	COG0083	homoserine kinase activity
IUJ49_08045	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
IUJ49_08050	COG4319	ketosteroid isomerase
IUJ49_08055	COG0488	(ABC) transporter
IUJ49_08070	COG0813	purine-nucleoside phosphorylase activity
IUJ49_08085	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IUJ49_08085	COG2205	protein histidine kinase activity
IUJ49_08090	COG3384	dioxygenase
IUJ49_08100	COG1283	sodium-dependent phosphate transmembrane transporter activity
IUJ49_08110	COG0531	amino acid
IUJ49_08120	COG0531	amino acid
IUJ49_08135	COG1396	sequence-specific DNA binding
IUJ49_08135	COG1917	Cupin 2, conserved barrel domain protein
IUJ49_08140	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
IUJ49_08160	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
IUJ49_08165	COG2375	cellular response to nickel ion
IUJ49_08175	COG1136	(ABC) transporter
IUJ49_08175	COG0577	efflux transmembrane transporter activity
IUJ49_08180	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IUJ49_08195	COG0497	DNA recombination
IUJ49_08200	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
IUJ49_08205	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
IUJ49_08210	COG0443	Heat shock 70 kDa protein
IUJ49_08215	COG0484	heat shock protein binding
IUJ49_08220	COG2239	Acts as a magnesium transporter
IUJ49_08230	COG1285	pathogenesis
IUJ49_08275	COG0095	Lipoate-protein ligase
IUJ49_08295	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
IUJ49_08300	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IUJ49_08320	COG0708	Exodeoxyribonuclease III
IUJ49_08335	COG2211	Major facilitator Superfamily
IUJ49_08385	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
IUJ49_08390	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
IUJ49_08395	COG1845	cytochrome c oxidase, subunit III
IUJ49_08400	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
IUJ49_08405	COG0109	protoheme IX farnesyltransferase activity
IUJ49_08410	COG2814	Major facilitator Superfamily
IUJ49_08425	COG3152	Membrane
IUJ49_08440	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
IUJ49_08490	COG0159	tryptophan synthase activity
IUJ49_08495	COG0133	tryptophan synthase activity
IUJ49_08500	COG0134	indole-3-glycerol-phosphate synthase activity
IUJ49_08500	COG0135	phosphoribosylanthranilate isomerase activity
IUJ49_08505	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
IUJ49_08510	COG0512	Glutamine amidotransferase of anthranilate synthase
IUJ49_08510	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
IUJ49_08515	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
IUJ49_08520	COG0613	PHP domain protein
IUJ49_08525	COG0009	L-threonylcarbamoyladenylate synthase
IUJ49_08535	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
IUJ49_08545	COG1946	Acyl-CoA thioesterase
IUJ49_08560	COG1309	transcriptional regulator
IUJ49_08565	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IUJ49_08570	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
IUJ49_08585	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
IUJ49_08605	COG0110	maltose O-acetyltransferase activity
IUJ49_08610	COG0110	maltose O-acetyltransferase activity
IUJ49_08630	COG0110	maltose O-acetyltransferase activity
IUJ49_08650	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
IUJ49_08670	COG3132	Protein of unknown function, DUF480
IUJ49_08710	COG1278	Cold shock
IUJ49_08745	COG1349	DNA-binding transcription factor activity
IUJ49_08750	COG1882	Formate acetyltransferase
IUJ49_08755	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
IUJ49_08760	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
IUJ49_08790	COG0622	Phosphoesterase
IUJ49_08805	COG1261	Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly
IUJ49_08810	COG0835	chemotaxis
IUJ49_08810	COG0784	Response regulator, receiver
IUJ49_08815	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
IUJ49_08820	COG1815	bacterial-type flagellum-dependent cell motility
IUJ49_08840	COG4787	bacterial-type flagellum-dependent cell motility
IUJ49_08850	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
IUJ49_08855	COG1706	bacterial-type flagellum-dependent cell motility
IUJ49_08860	COG1705	Flagellar rod assembly protein muramidase FlgJ
IUJ49_08860	COG3951	Flagellar rod assembly protein muramidase FlgJ
IUJ49_08865	COG1256	bacterial-type flagellum assembly
IUJ49_08875	COG2239	Acts as a magnesium transporter
IUJ49_08885	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
IUJ49_08890	COG2716	regulation of RNA biosynthetic process
IUJ49_08915	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
IUJ49_08920	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
IUJ49_08925	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
IUJ49_08930	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
IUJ49_08950	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
IUJ49_08970	COG0573	inorganic phosphate transmembrane transporter activity
IUJ49_08975	COG0581	inorganic phosphate transmembrane transporter activity
IUJ49_08980	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
IUJ49_08985	COG0704	Plays a role in the regulation of phosphate uptake
IUJ49_08990	COG1253	flavin adenine dinucleotide binding
IUJ49_09005	COG0531	amino acid
IUJ49_09025	COG1126	abc transporter atp-binding protein
IUJ49_09030	COG0765	amino acid transport
IUJ49_09035	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IUJ49_09045	COG2271	Major facilitator Superfamily
IUJ49_09060	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
IUJ49_09085	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
IUJ49_09090	COG0477	Major facilitator Superfamily
IUJ49_09095	COG0123	including yeast histone deacetylase and acetoin utilization protein
IUJ49_09105	COG1199	ATP-dependent helicase activity
IUJ49_09120	COG1448	Aminotransferase
IUJ49_09125	COG0433	COG0433 Predicted ATPase
IUJ49_09140	COG0658	competence protein
IUJ49_09140	COG2333	competence protein COMEC
IUJ49_09150	COG1663	tetraacyldisaccharide 4'-kinase activity
IUJ49_09155	COG2835	tetraacyldisaccharide 4'-kinase activity
IUJ49_09160	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
IUJ49_09165	COG2197	response regulator
IUJ49_09170	COG0322	excinuclease ABC activity
IUJ49_09205	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
IUJ49_09215	COG4974	Belongs to the 'phage' integrase family
IUJ49_09255	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
IUJ49_09260	COG0437	4 iron, 4 sulfur cluster binding
IUJ49_09265	COG3301	Polysulphide reductase, NrfD
IUJ49_09270	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
IUJ49_09280	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
IUJ49_09300	COG2199	diguanylate cyclase activity
IUJ49_09300	COG2203	Gaf domain
IUJ49_09330	COG2119	membrane
IUJ49_09335	COG0023	Translation Initiation Factor
IUJ49_09360	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
IUJ49_09375	COG2205	protein histidine kinase activity
IUJ49_09375	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IUJ49_09385	COG4138	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system
IUJ49_09395	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
IUJ49_09400	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
IUJ49_09405	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
IUJ49_09410	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
IUJ49_09415	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
IUJ49_09425	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
IUJ49_09430	COG0505	Belongs to the CarA family
IUJ49_09435	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
IUJ49_09440	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
IUJ49_09470	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
IUJ49_09475	COG0513	Belongs to the DEAD box helicase family
IUJ49_09485	COG4104	PAAR repeat-containing protein
IUJ49_09500	COG0789	Transcriptional regulator
IUJ49_09515	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IUJ49_09520	COG0765	amino acid transport
IUJ49_09525	COG1126	abc transporter atp-binding protein
IUJ49_09530	COG0493	'glutamate synthase
IUJ49_09535	COG0067	glutamate synthase
IUJ49_09535	COG0069	glutamate synthase activity
IUJ49_09535	COG0070	glutamate synthase
IUJ49_09540	COG1242	4 iron, 4 sulfur cluster binding
IUJ49_09605	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
IUJ49_09610	COG0574	Belongs to the PEP-utilizing enzyme family
IUJ49_09610	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
IUJ49_09650	COG1464	Belongs to the NlpA lipoprotein family
IUJ49_09655	COG0671	phosphoesterase, PA-phosphatase related
IUJ49_09660	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
IUJ49_09665	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
IUJ49_09675	COG0101	tRNA pseudouridine synthase activity
IUJ49_09680	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
IUJ49_09685	COG0285	dihydrofolate synthase activity
IUJ49_09690	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
IUJ49_09695	COG2920	part of a sulfur-relay system
IUJ49_09700	COG1289	transmembrane transporter activity
IUJ49_09705	COG0670	Belongs to the BI1 family
IUJ49_09720	COG4792	protein secretion
IUJ49_09725	COG4791	protein targeting
IUJ49_09730	COG4794	Type iii secretion
IUJ49_09735	COG4790	Type iii secretion
IUJ49_09895	COG1317	bacterial-type flagellum organization
IUJ49_09910	COG2194	sulfuric ester hydrolase activity
IUJ49_09915	COG0392	lysyltransferase activity
IUJ49_09915	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
IUJ49_09925	COG0840	transmembrane signaling receptor activity
IUJ49_09930	COG5001	Diguanylate cyclase
IUJ49_09935	COG0564	pseudouridine synthase activity
IUJ49_09950	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
IUJ49_09960	COG0625	glutathione transferase activity
IUJ49_09965	COG0625	glutathione transferase activity
IUJ49_09975	COG0367	asparagine synthase
IUJ49_09985	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
IUJ49_09985	COG4651	solute:proton antiporter activity
IUJ49_09990	COG0647	UMP catabolic process
IUJ49_09995	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
IUJ49_10000	COG1902	pentaerythritol trinitrate reductase activity
IUJ49_10005	COG1253	flavin adenine dinucleotide binding
IUJ49_10015	COG0247	lactate metabolic process
IUJ49_10015	COG0277	FAD linked oxidase domain protein
IUJ49_10025	COG2050	protein possibly involved in aromatic compounds catabolism
IUJ49_10035	COG2056	Na+-H+ antiporter family
IUJ49_10040	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
IUJ49_10055	COG0346	lactoylglutathione lyase activity
IUJ49_10060	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
IUJ49_10065	COG4660	Part of a membrane complex involved in electron transport
IUJ49_10070	COG4659	FMN binding
IUJ49_10075	COG4658	electron transport chain
IUJ49_10085	COG2878	Part of a membrane complex involved in electron transport
IUJ49_10090	COG4657	Part of a membrane complex involved in electron transport
IUJ49_10095	COG0697	spore germination
IUJ49_10105	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
IUJ49_10110	COG1288	antiporter activity
IUJ49_10115	COG0436	Aminotransferase
IUJ49_10125	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
IUJ49_10130	COG2027	D-alanyl-D-alanine carboxypeptidase
IUJ49_10135	COG1061	Type III restriction enzyme res subunit
IUJ49_10140	COG1566	PFAM secretion protein HlyD family protein
IUJ49_10150	COG1966	Carbon starvation protein
IUJ49_10155	COG3279	Response regulator of the LytR AlgR family
IUJ49_10160	COG3275	phosphorelay sensor kinase activity
IUJ49_10165	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
IUJ49_10165	COG2199	diguanylate cyclase activity
IUJ49_10170	COG1012	belongs to the aldehyde dehydrogenase family
IUJ49_10170	COG1454	alcohol dehydrogenase
IUJ49_10180	COG2095	MarC family integral membrane protein
IUJ49_10190	COG0601	transmembrane transport
IUJ49_10195	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
IUJ49_10210	COG0861	Integral membrane protein TerC family
IUJ49_10215	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
IUJ49_10225	COG1301	dicarboxylic acid transport
IUJ49_10240	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
IUJ49_10255	COG0537	adenosine 5'-monophosphoramidase activity
IUJ49_10290	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
IUJ49_10295	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
IUJ49_10305	COG2354	Protein conserved in bacteria
IUJ49_10320	COG2233	PERMEase
IUJ49_10325	COG3150	esterase
IUJ49_10330	COG1252	NADH dehydrogenase
IUJ49_10350	COG0393	Putative heavy-metal-binding
IUJ49_10360	COG1619	proteins homologs of microcin C7 resistance protein MccF
IUJ49_10365	COG1368	sulfuric ester hydrolase activity
IUJ49_10375	COG0527	aspartate kinase activity
IUJ49_10380	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
IUJ49_10380	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
IUJ49_10385	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
IUJ49_10405	COG0596	Alpha beta hydrolase
IUJ49_10410	COG0346	lactoylglutathione lyase activity
IUJ49_10420	COG0583	DNA-binding transcription factor activity
IUJ49_10435	COG1139	Iron-sulfur cluster binding protein
IUJ49_10480	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
IUJ49_10485	COG0840	transmembrane signaling receptor activity
IUJ49_10495	COG2201	protein-glutamate methylesterase activity
IUJ49_10505	COG0835	chemotaxis
IUJ49_10510	COG0840	transmembrane signaling receptor activity
IUJ49_10510	COG3290	protein histidine kinase activity
IUJ49_10515	COG0643	Histidine kinase
IUJ49_10515	COG2198	Histidine kinase
IUJ49_10525	COG0745	RESPONSE REGULATOR receiver
IUJ49_10530	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
IUJ49_10535	COG0437	4 iron, 4 sulfur cluster binding
IUJ49_10540	COG5557	Pfam Polysulphide reductase, NrfD
IUJ49_10545	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
IUJ49_10550	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
IUJ49_10555	COG1773	rubredoxin
IUJ49_10565	COG0601	transmembrane transport
IUJ49_10570	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
IUJ49_10580	COG3842	ATPase activity
IUJ49_10585	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
IUJ49_10590	COG0375	protein maturation
IUJ49_10595	COG0309	Hydrogenase expression formation protein (HypE)
IUJ49_10605	COG0298	carbon dioxide binding
IUJ49_10610	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
IUJ49_10620	COG1921	L-seryl-tRNASec selenium transferase activity
IUJ49_10630	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
IUJ49_10640	COG3260	NADH ubiquinone oxidoreductase 20
IUJ49_10645	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
IUJ49_10650	COG3261	NADH dehydrogenase
IUJ49_10650	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
IUJ49_10655	COG0650	Formate hydrogenlyase subunit 4
IUJ49_10660	COG0651	ATP synthesis coupled electron transport
IUJ49_10665	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
IUJ49_10670	COG3158	transport of potassium into the cell
IUJ49_10680	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
IUJ49_10705	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
IUJ49_10710	COG0326	Molecular chaperone. Has ATPase activity
IUJ49_10715	COG0563	adenylate kinase activity
IUJ49_10720	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
IUJ49_10730	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IUJ49_10745	COG3300	MHYT domain
IUJ49_10745	COG5001	Diguanylate cyclase
IUJ49_10750	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
IUJ49_10770	COG1021	2,3-dihydroxybenzoate-AMP ligase
IUJ49_10775	COG1535	isochorismatase
IUJ49_10775	COG3433	isochorismatase activity
IUJ49_10780	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
IUJ49_10785	COG1028	Short-chain dehydrogenase reductase Sdr
IUJ49_10795	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
IUJ49_10800	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
IUJ49_10810	COG1120	ATPase activity
IUJ49_10815	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IUJ49_10820	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IUJ49_10825	COG4771	TonB-dependent receptor
IUJ49_10865	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
IUJ49_10870	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
IUJ49_10875	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
IUJ49_10890	COG1570	exodeoxyribonuclease VII activity
IUJ49_10895	COG0697	spore germination
IUJ49_10915	COG3158	transport of potassium into the cell
IUJ49_10920	COG0516	GMP reductase activity
IUJ49_10920	COG0517	IMP dehydrogenase activity
IUJ49_10925	COG0519	Catalyzes the synthesis of GMP from XMP
IUJ49_10925	COG0518	GMP synthase (glutamine-hydrolyzing) activity
IUJ49_10965	COG2062	phosphohistidine phosphatase, SixA
IUJ49_10975	COG0697	spore germination
IUJ49_10980	COG4166	transmembrane transport
IUJ49_10985	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
IUJ49_10990	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
IUJ49_11000	COG4591	ABC-type transport system involved in lipoprotein release permease component
IUJ49_11005	COG1136	(ABC) transporter
IUJ49_11010	COG4591	ABC-type transport system involved in lipoprotein release permease component
IUJ49_11015	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
IUJ49_11025	COG0544	peptidyl-prolyl cis-trans isomerase activity
IUJ49_11030	COG0740	serine-type endopeptidase activity
IUJ49_11035	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
IUJ49_11040	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
IUJ49_11045	COG0776	regulation of translation
IUJ49_11050	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
IUJ49_11055	COG0488	(ABC) transporter
IUJ49_11060	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
IUJ49_11065	COG3162	membrane
IUJ49_11080	COG1024	Enoyl-CoA hydratase
IUJ49_11120	COG1115	amino acid carrier protein
IUJ49_11135	COG1584	GPR1 FUN34 yaaH family protein
IUJ49_11170	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
IUJ49_11175	COG1960	acyl-CoA dehydrogenase activity
IUJ49_11185	COG1960	acyl-CoA dehydrogenase activity
IUJ49_11190	COG1024	Enoyl-CoA hydratase
IUJ49_11195	COG1024	Enoyl-CoA hydratase
IUJ49_11205	COG1028	Short-chain dehydrogenase reductase Sdr
IUJ49_11215	COG0730	response to heat
IUJ49_11225	COG0583	DNA-binding transcription factor activity
IUJ49_11230	COG0667	Aldo Keto reductase
IUJ49_11245	COG3706	GGDEF domain
IUJ49_11250	COG0583	DNA-binding transcription factor activity
IUJ49_11255	COG2723	6-phospho-beta-galactosidase activity
IUJ49_11260	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
IUJ49_11270	COG0583	DNA-binding transcription factor activity
IUJ49_11275	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
IUJ49_11280	COG0673	inositol 2-dehydrogenase activity
IUJ49_11285	COG0583	DNA-binding transcription factor activity
IUJ49_11295	COG1560	Kdo2-lipid A biosynthetic process
IUJ49_11300	COG1560	Kdo2-lipid A biosynthetic process
IUJ49_11325	COG0417	DNA replication proofreading
IUJ49_11350	COG0534	Mate efflux family protein
IUJ49_11360	COG0307	riboflavin synthase, alpha
IUJ49_11370	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
IUJ49_11375	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
IUJ49_11380	COG0697	spore germination
IUJ49_11385	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
IUJ49_11425	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
IUJ49_11430	COG3099	Belongs to the UPF0263 family
IUJ49_11435	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
IUJ49_11440	COG2894	cell division
IUJ49_11445	COG0850	regulation of cytokinetic process
IUJ49_11450	COG3100	YcgL domain-containing protein
IUJ49_11455	COG2951	lytic endotransglycosylase activity
IUJ49_11460	COG1760	l-serine dehydratase
IUJ49_11465	COG1760	l-serine dehydratase
IUJ49_11470	COG3123	guanosine phosphorylase activity
IUJ49_11500	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
IUJ49_11505	COG2067	long-chain fatty acid transport protein
IUJ49_11520	COG1595	DNA-templated transcription, initiation
IUJ49_11550	COG0714	Associated with various cellular activities
IUJ49_11555	COG0183	Belongs to the thiolase family
IUJ49_11560	COG1250	3-hydroxyacyl-CoA dehydrogenase
IUJ49_11560	COG1024	Enoyl-CoA hydratase
IUJ49_11615	COG3829	transcription factor binding
IUJ49_11620	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
IUJ49_11625	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
IUJ49_11630	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
IUJ49_11640	COG0549	Belongs to the carbamate kinase family
IUJ49_11645	COG0697	spore germination
IUJ49_11650	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
IUJ49_11650	COG3608	succinylglutamate desuccinylase aspartoacylase
IUJ49_11655	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
IUJ49_11660	COG2068	MobA-Related Protein
IUJ49_11665	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
IUJ49_11665	COG0493	'glutamate synthase
IUJ49_11670	COG0402	S-adenosylhomocysteine deaminase activity
IUJ49_11675	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
IUJ49_11680	COG2080	2 iron, 2 sulfur cluster binding
IUJ49_11680	COG1529	Aldehyde oxidase and xanthine dehydrogenase
IUJ49_11685	COG2233	PERMEase
IUJ49_11690	COG0402	S-adenosylhomocysteine deaminase activity
IUJ49_11695	COG2252	PERMEase
IUJ49_11700	COG1529	Aldehyde oxidase and xanthine dehydrogenase
IUJ49_11705	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
IUJ49_11710	COG2080	2 iron, 2 sulfur cluster binding
IUJ49_11720	COG3134	Outer membrane lipoprotein
IUJ49_11730	COG1288	antiporter activity
IUJ49_11735	COG0318	PFAM AMP-dependent synthetase and ligase
IUJ49_11745	COG0140	phosphoribosyl-ATP diphosphatase activity
IUJ49_11745	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
IUJ49_11750	COG0107	imidazoleglycerol-phosphate synthase activity
IUJ49_11755	COG0784	Response regulator, receiver
IUJ49_11755	COG2198	Histidine kinase
IUJ49_11755	COG2205	protein histidine kinase activity
IUJ49_11760	COG2199	diguanylate cyclase activity
IUJ49_11765	COG3437	response regulator, receiver
IUJ49_11770	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
IUJ49_11775	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
IUJ49_11780	COG0131	Imidazoleglycerol-phosphate dehydratase
IUJ49_11780	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
IUJ49_11785	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
IUJ49_11790	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
IUJ49_11795	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
IUJ49_11805	COG1199	ATP-dependent helicase activity
IUJ49_11810	COG1214	PFAM Peptidase M22, glycoprotease
IUJ49_11820	COG0596	Alpha beta hydrolase
IUJ49_11820	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
IUJ49_11820	COG2226	methyltransferase
IUJ49_11825	COG0318	PFAM AMP-dependent synthetase and ligase
IUJ49_11830	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
IUJ49_11845	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
IUJ49_11850	COG2832	Protein of unknown function (DUF454)
IUJ49_11855	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
IUJ49_11865	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
IUJ49_11880	COG0517	IMP dehydrogenase activity
IUJ49_11880	COG0617	tRNA 3'-terminal CCA addition
IUJ49_11880	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
IUJ49_11885	COG1643	Atp-dependent helicase
IUJ49_11895	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
IUJ49_11905	COG3437	response regulator, receiver
IUJ49_11910	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
IUJ49_11915	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
IUJ49_11920	COG0709	Synthesizes selenophosphate from selenide and ATP
IUJ49_11935	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
IUJ49_11945	COG1254	Belongs to the acylphosphatase family
IUJ49_11950	COG0625	glutathione transferase activity
IUJ49_11955	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
IUJ49_11955	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
IUJ49_11960	COG0489	protein tyrosine kinase activity
IUJ49_11965	COG0572	uridine kinase
IUJ49_11970	COG0717	Belongs to the dCTP deaminase family
IUJ49_11975	COG0306	phosphate transporter
IUJ49_11980	COG1530	ribonuclease E activity
IUJ49_11985	COG0564	pseudouridine synthase activity
IUJ49_11990	COG0546	phosphoglycolate phosphatase activity
IUJ49_11995	COG0424	maF-like protein
IUJ49_12000	COG2814	Major facilitator Superfamily
IUJ49_12015	COG1399	metal-binding, possibly nucleic acid-binding protein
IUJ49_12020	COG0333	Belongs to the bacterial ribosomal protein bL32 family
IUJ49_12025	COG0416	fatty acid biosynthetic process
IUJ49_12030	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
IUJ49_12040	COG1028	Short-chain dehydrogenase reductase Sdr
IUJ49_12045	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
IUJ49_12055	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
IUJ49_12060	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
IUJ49_12065	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
IUJ49_12070	COG0470	DNA polymerase III
IUJ49_12075	COG0084	hydrolase, TatD family'
IUJ49_12090	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
IUJ49_12090	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
IUJ49_12095	COG3008	intermembrane lipid transfer
IUJ49_12100	COG2995	paraquat-inducible protein a
IUJ49_12110	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
IUJ49_12115	COG0372	Belongs to the citrate synthase family
IUJ49_12160	COG4221	oxidoreductase activity
IUJ49_12170	COG3141	response to X-ray
IUJ49_12195	COG4128	Pfam Zonular occludens toxin
IUJ49_12235	COG1067	ATP-dependent peptidase activity
IUJ49_12240	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
IUJ49_12255	COG0488	(ABC) transporter
IUJ49_12265	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
IUJ49_12265	COG0116	Belongs to the methyltransferase superfamily
IUJ49_12275	COG0167	dihydroorotate dehydrogenase activity
IUJ49_12280	COG2902	Dehydrogenase
IUJ49_12290	COG0308	aminopeptidase N
IUJ49_12300	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
IUJ49_12305	COG1956	GAF domain-containing protein
IUJ49_12315	COG3278	Belongs to the heme-copper respiratory oxidase family
IUJ49_12330	COG2010	Cytochrome c
IUJ49_12355	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
IUJ49_12360	COG0589	response to stress
IUJ49_12365	COG0037	tRNA processing
IUJ49_12385	COG1869	D-ribose catabolic process
IUJ49_12390	COG1129	ABC transporter
IUJ49_12395	COG1172	Belongs to the binding-protein-dependent transport system permease family
IUJ49_12400	COG1879	ABC-type sugar transport system periplasmic component
IUJ49_12405	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IUJ49_12410	COG1609	Transcriptional regulator
IUJ49_12415	COG2199	diguanylate cyclase activity
IUJ49_12445	COG0776	regulation of translation
IUJ49_12450	COG0072	phenylalanine-tRNA ligase activity
IUJ49_12450	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
IUJ49_12455	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
IUJ49_12460	COG4974	Belongs to the 'phage' integrase family
IUJ49_12480	COG3620	sequence-specific DNA binding
IUJ49_12540	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
IUJ49_12570	COG4695	Portal protein
IUJ49_12690	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
IUJ49_12695	COG0291	Belongs to the bacterial ribosomal protein bL35 family
IUJ49_12700	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
IUJ49_12705	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
IUJ49_12730	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
IUJ49_12740	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
IUJ49_12745	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
IUJ49_12750	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
IUJ49_12755	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
IUJ49_12760	COG3313	Fe-S protein
IUJ49_12765	COG2942	2-epimerase
IUJ49_12770	COG3716	PTS system mannose fructose sorbose family IID component
IUJ49_12775	COG3715	PTS system
IUJ49_12780	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
IUJ49_12780	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
IUJ49_12795	COG1609	Transcriptional regulator
IUJ49_12800	COG2140	Oxalate decarboxylase
IUJ49_12805	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
IUJ49_12805	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
IUJ49_12805	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
IUJ49_12810	COG1105	Belongs to the carbohydrate kinase PfkB family
IUJ49_12815	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
IUJ49_12815	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
IUJ49_12820	COG1609	Transcriptional regulator
IUJ49_12825	COG0814	amino acid
IUJ49_12835	COG5654	RES domain protein
IUJ49_12840	COG0513	Belongs to the DEAD box helicase family
IUJ49_12850	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
IUJ49_12855	COG2890	protein-(glutamine-N5) methyltransferase activity
IUJ49_12860	COG2840	Smr protein MutS2
IUJ49_12870	COG3706	GGDEF domain
IUJ49_12875	COG0588	phosphoglycerate mutase activity
IUJ49_12900	COG2824	Alkylphosphonate utilization operon protein PhnA
IUJ49_12910	COG0384	phenazine biosynthesis protein PhzF
IUJ49_12925	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IUJ49_12925	COG2205	protein histidine kinase activity
IUJ49_12940	COG3188	usher protein
IUJ49_12945	COG3121	Chaperone
IUJ49_12960	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
IUJ49_12985	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
IUJ49_12990	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
IUJ49_13000	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
IUJ49_13005	COG1434	Gram-negative-bacterium-type cell wall biogenesis
IUJ49_13015	COG0205	6-phosphofructokinase activity
IUJ49_13020	COG1473	amidohydrolase
IUJ49_13025	COG1011	Hydrolase
IUJ49_13030	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
IUJ49_13080	COG3593	DNA synthesis involved in DNA repair
IUJ49_13095	COG0583	DNA-binding transcription factor activity
IUJ49_13100	COG0730	response to heat
IUJ49_13110	COG3148	PFAM DTW domain containing protein
IUJ49_13120	COG1181	Belongs to the D-alanine--D-alanine ligase family
IUJ49_13130	COG0386	Belongs to the glutathione peroxidase family
IUJ49_13135	COG0513	Belongs to the DEAD box helicase family
IUJ49_13140	COG0456	acetyltransferase
IUJ49_13150	COG1742	UPF0060 membrane protein
IUJ49_13180	COG2329	Antibiotic biosynthesis monooxygenase
IUJ49_13185	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
IUJ49_13205	COG3243	poly(R)-hydroxyalkanoic acid synthase
IUJ49_13215	COG2501	S4 domain
IUJ49_13230	COG1132	(ABC) transporter
IUJ49_13235	COG1132	(ABC) transporter
IUJ49_13245	COG3118	belongs to the thioredoxin family
IUJ49_13250	COG0471	metal ion transport
IUJ49_13255	COG0058	SHG alpha-glucan phosphorylase activity
IUJ49_13285	COG0814	amino acid
IUJ49_13290	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
IUJ49_13295	COG0514	ATP-dependent DNA helicase (RecQ)
IUJ49_13300	COG2766	serine protein kinase
IUJ49_13310	COG2719	SpoVR family
IUJ49_13315	COG2186	Transcriptional regulator
IUJ49_13320	COG3067	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
IUJ49_13325	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
IUJ49_13330	COG0586	Pfam SNARE associated Golgi protein
IUJ49_13340	COG0556	nucleotide-excision repair
IUJ49_13350	COG0569	domain protein
IUJ49_13350	COG2985	domain, Protein
IUJ49_13355	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
IUJ49_13375	COG4565	transcriptional regulatory protein
IUJ49_13380	COG3290	protein histidine kinase activity
IUJ49_13385	COG1846	Transcriptional regulator
IUJ49_13385	COG1940	carbohydrate kinase activity
IUJ49_13390	COG0840	transmembrane signaling receptor activity
IUJ49_13395	COG3012	SEC-C Motif Domain Protein
IUJ49_13400	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
IUJ49_13405	COG3075	Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses fumarate or nitrate as electron acceptor
IUJ49_13410	COG0247	lactate metabolic process
IUJ49_13430	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
IUJ49_13435	COG0437	4 iron, 4 sulfur cluster binding
IUJ49_13440	COG3301	Polysulphide reductase, NrfD
IUJ49_13445	COG1138	Cytochrome C-type biogenesis protein
IUJ49_13450	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
IUJ49_13455	COG3088	subunit of a heme lyase
IUJ49_13455	COG4235	cytochrome complex assembly
IUJ49_13460	COG1051	belongs to the nudix hydrolase family
IUJ49_13470	COG3033	Beta-eliminating lyase
IUJ49_13480	COG3046	protein related to deoxyribodipyrimidine photolyase
IUJ49_13485	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
IUJ49_13510	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
IUJ49_13525	COG4774	siderophore transport
IUJ49_13530	COG4977	sequence-specific DNA binding
IUJ49_13540	COG0583	DNA-binding transcription factor activity
IUJ49_13545	COG2910	NAD(P)H-binding
IUJ49_13560	COG0612	Peptidase, M16
IUJ49_13565	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
IUJ49_13575	COG1944	ATP diphosphatase activity
IUJ49_13580	COG2116	formate transmembrane transporter activity
IUJ49_13585	COG1882	Formate acetyltransferase
IUJ49_13590	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
IUJ49_13600	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
IUJ49_13610	COG1840	ABC-type Fe3 transport system, periplasmic component
IUJ49_13615	COG3842	ATPase activity
IUJ49_13625	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
IUJ49_13630	COG2983	Belongs to the UPF0260 family
IUJ49_13645	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
IUJ49_13650	COG0045	succinate-CoA ligase (ADP-forming) activity
IUJ49_13655	COG0508	dehydrogenase complex catalyzes the overall conversion of
IUJ49_13660	COG0567	Dehydrogenase, E1 component
IUJ49_13670	COG1053	succinate dehydrogenase
IUJ49_13675	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
IUJ49_13700	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
IUJ49_13705	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
IUJ49_13705	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
IUJ49_13715	COG3069	C4-dicarboxylate transmembrane transporter activity
IUJ49_13730	COG1451	nucleotide metabolic process
IUJ49_13745	COG0254	rRNA binding
IUJ49_13750	COG0257	Belongs to the bacterial ribosomal protein bL36 family
IUJ49_13760	COG0583	DNA-binding transcription factor activity
IUJ49_13770	COG1172	Belongs to the binding-protein-dependent transport system permease family
IUJ49_13780	COG1879	ABC-type sugar transport system periplasmic component
IUJ49_13785	COG1069	ribulokinase activity
IUJ49_13795	COG2160	L-arabinose isomerase activity
IUJ49_13800	COG2925	Exonuclease
IUJ49_13810	COG3345	alpha-galactosidase
IUJ49_13815	COG1380	Effector of murein hydrolase LrgA
IUJ49_13820	COG1346	cytolysis
IUJ49_13825	COG0295	cytidine deaminase activity
IUJ49_13830	COG1022	Amp-dependent synthetase and ligase
IUJ49_13845	COG0861	Integral membrane protein TerC family
IUJ49_13850	COG2885	chlorophyll binding
IUJ49_13855	COG2199	diguanylate cyclase activity
IUJ49_13880	COG2154	pterin-4-alpha-carbinolamine dehydratase
IUJ49_13890	COG3768	UPF0283 membrane protein
IUJ49_13895	COG3106	COG3106 Predicted ATPase
IUJ49_13910	COG1842	Phage shock protein A
IUJ49_13915	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
IUJ49_13925	COG4168	peptide transport system, permease
IUJ49_13930	COG4171	peptide transport system, permease
IUJ49_13940	COG4172	Belongs to the ABC transporter superfamily
IUJ49_13950	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
IUJ49_13955	COG1286	toxin biosynthetic process
IUJ49_13960	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
IUJ49_13965	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
IUJ49_13970	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
IUJ49_13975	COG0531	amino acid
IUJ49_13975	COG1674	ftsk spoiiie
IUJ49_13985	COG0686	Belongs to the AlaDH PNT family
IUJ49_13990	COG0492	ferredoxin-NADP+ reductase activity
IUJ49_13995	COG3706	GGDEF domain
IUJ49_14000	COG3134	Outer membrane lipoprotein
IUJ49_14005	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
IUJ49_14010	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
IUJ49_14015	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
IUJ49_14020	COG0542	response to heat
IUJ49_14025	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
IUJ49_14030	COG1278	Cold shock
IUJ49_14035	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
IUJ49_14095	COG3829	transcription factor binding
IUJ49_14160	COG3209	COG3209 Rhs family protein
IUJ49_14170	COG3501	Rhs element vgr protein
IUJ49_14185	COG0659	secondary active sulfate transmembrane transporter activity
IUJ49_14215	COG0672	)-iron permease
IUJ49_14235	COG2814	Major facilitator Superfamily
IUJ49_14245	COG1136	(ABC) transporter
IUJ49_14250	COG0577	efflux transmembrane transporter activity
IUJ49_14275	COG1435	thymidine kinase activity
IUJ49_14280	COG1757	Na H antiporter
IUJ49_14285	COG2916	Histone family protein nucleoid-structuring protein H-NS
IUJ49_14290	COG2096	Adenosyltransferase
IUJ49_14295	COG3530	Putative quorum-sensing-regulated virulence factor
IUJ49_14300	COG0602	queuosine metabolic process
IUJ49_14305	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
IUJ49_14325	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
IUJ49_14335	COG0776	regulation of translation
IUJ49_14340	COG0539	negative regulation of cytoplasmic translation
IUJ49_14345	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
IUJ49_14350	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
IUJ49_14360	COG0583	DNA-binding transcription factor activity
IUJ49_14365	COG2814	Major facilitator Superfamily
IUJ49_14380	COG0778	Nitroreductase
IUJ49_14385	COG5001	Diguanylate cyclase
IUJ49_14385	COG3300	MHYT domain
IUJ49_14395	COG0583	DNA-binding transcription factor activity
IUJ49_14400	COG3437	response regulator, receiver
IUJ49_14425	COG4989	oxidoreductase activity
IUJ49_14430	COG0724	RNA recognition motif
IUJ49_14450	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
IUJ49_14470	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
IUJ49_14475	COG1360	Flagellar Motor Protein
IUJ49_14480	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
IUJ49_14485	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
IUJ49_14490	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
IUJ49_14490	COG0649	NAD binding
IUJ49_14505	COG1034	ATP synthesis coupled electron transport
IUJ49_14510	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
IUJ49_14515	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
IUJ49_14520	COG0839	Belongs to the complex I subunit 6 family
IUJ49_14525	COG0713	ATP synthesis coupled electron transport
IUJ49_14535	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
IUJ49_14540	COG1007	ATP synthesis coupled electron transport
IUJ49_14545	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
IUJ49_14545	COG0047	phosphoribosylformylglycinamidine synthase activity
IUJ49_14550	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
IUJ49_14555	COG1645	bacterial-type flagellum-dependent swarming motility
IUJ49_14560	COG1160	GTP binding
IUJ49_14565	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
IUJ49_14570	COG2976	Protein conserved in bacteria
IUJ49_14575	COG0124	histidyl-tRNA synthetase
IUJ49_14580	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
IUJ49_14595	COG0820	rRNA (adenine-C2-)-methyltransferase activity
IUJ49_14600	COG0105	UTP biosynthetic process
IUJ49_14605	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
IUJ49_14615	COG0633	Ferredoxin
IUJ49_14620	COG0443	Heat shock 70 kDa protein
IUJ49_14625	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
IUJ49_14635	COG0822	iron-sulfur transferase activity
IUJ49_14640	COG1104	cysteine desulfurase activity
IUJ49_14660	COG3154	lipid carrier protein
IUJ49_14665	COG0826	peptidase U32
IUJ49_14670	COG0826	peptidase U32
IUJ49_14685	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
IUJ49_14690	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
IUJ49_14695	COG1862	Preprotein translocase
IUJ49_14700	COG0343	queuine tRNA-ribosyltransferase activity
IUJ49_14705	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
IUJ49_14710	COG0517	IMP dehydrogenase activity
IUJ49_14720	COG3634	alkyl hydroperoxide reductase activity
IUJ49_14725	COG0477	Major facilitator Superfamily
IUJ49_14740	COG1393	Belongs to the ArsC family
IUJ49_14745	COG0798	PFAM Bile acid sodium symporter
IUJ49_14760	COG0640	Transcriptional regulator
IUJ49_14775	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
IUJ49_14775	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
IUJ49_14780	COG0509	glycine decarboxylation via glycine cleavage system
IUJ49_14785	COG0404	The glycine cleavage system catalyzes the degradation of glycine
IUJ49_14790	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
IUJ49_14795	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
IUJ49_14815	COG2814	Major facilitator Superfamily
IUJ49_14820	COG0625	glutathione transferase activity
IUJ49_14830	COG0483	inositol monophosphate 1-phosphatase activity
IUJ49_14835	COG0840	transmembrane signaling receptor activity
IUJ49_14850	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
IUJ49_14915	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
IUJ49_14915	COG0301	tRNA thio-modification
IUJ49_14925	COG4953	penicillin-binding protein 1C
IUJ49_14930	COG2373	Large extracellular alpha-helical protein
IUJ49_14935	COG0446	pyridine nucleotide-disulphide oxidoreductase
IUJ49_14945	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
IUJ49_14965	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IUJ49_14975	COG2431	L-lysine efflux transmembrane transporter activity
IUJ49_14980	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
IUJ49_14985	COG3124	Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP
IUJ49_15000	COG1393	Belongs to the ArsC family
IUJ49_15010	COG4783	chaperone-mediated protein folding
IUJ49_15015	COG0425	Belongs to the sulfur carrier protein TusA family
IUJ49_15040	COG3842	ATPase activity
IUJ49_15045	COG3833	ABC-type maltose transport systems, permease component
IUJ49_15050	COG1175	transmembrane transport
IUJ49_15060	COG3081	Nucleoid-associated protein
IUJ49_15065	COG3082	Protein of unknown function (DUF1414)
IUJ49_15070	COG3083	sulfuric ester hydrolase activity
IUJ49_15075	COG4771	TonB-dependent receptor
IUJ49_15080	COG1770	oligopeptidase
IUJ49_15100	COG4574	serine-type endopeptidase inhibitor activity
IUJ49_15105	COG3085	chromosome segregation
IUJ49_15110	COG0583	DNA-binding transcription factor activity
IUJ49_15115	COG0287	Prephenate dehydrogenase
IUJ49_15115	COG1605	Chorismate mutase
IUJ49_15120	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
IUJ49_15125	COG0584	glycerophosphoryl diester phosphodiesterase
IUJ49_15135	COG1349	DNA-binding transcription factor activity
IUJ49_15140	COG2271	Major facilitator Superfamily
IUJ49_15145	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
IUJ49_15150	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
IUJ49_15155	COG0583	DNA-binding transcription factor activity
IUJ49_15175	COG0656	L-ascorbic acid biosynthetic process
IUJ49_15180	COG2814	Major facilitator Superfamily
IUJ49_15190	COG1294	oxidase, subunit
IUJ49_15195	COG1271	oxidase subunit
IUJ49_15200	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
IUJ49_15210	COG2979	Protein of unknown function (DUF533)
IUJ49_15235	COG2271	Major facilitator Superfamily
IUJ49_15240	COG0583	DNA-binding transcription factor activity
IUJ49_15250	COG2807	transmembrane transport
IUJ49_15260	COG1187	pseudouridine synthase activity
IUJ49_15275	COG0346	lactoylglutathione lyase activity
IUJ49_15310	COG2964	Protein conserved in bacteria
IUJ49_15315	COG3681	Belongs to the UPF0597 family
IUJ49_15325	COG0814	amino acid
IUJ49_15345	COG1166	arginine decarboxylase activity
IUJ49_15355	COG2195	Cleaves the N-terminal amino acid of tripeptides
IUJ49_15385	COG0583	DNA-binding transcription factor activity
IUJ49_15395	COG2759	Belongs to the formate--tetrahydrofolate ligase family
IUJ49_15400	COG0840	transmembrane signaling receptor activity
IUJ49_15405	COG0302	gtp cyclohydrolase
IUJ49_15415	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
IUJ49_15445	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
IUJ49_15460	COG0314	molybdopterin synthase activity
IUJ49_15465	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
IUJ49_15470	COG0315	cyclic pyranopterin monophosphate synthase activity
IUJ49_15475	COG0521	Mo-molybdopterin cofactor biosynthetic process
IUJ49_15480	COG3005	denitrification pathway
IUJ49_15490	COG0348	domain, Protein
IUJ49_15495	COG0437	4 iron, 4 sulfur cluster binding
IUJ49_15500	COG0243	molybdopterin cofactor binding
IUJ49_15510	COG1149	4fe-4S ferredoxin, iron-sulfur binding domain protein
IUJ49_15510	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
IUJ49_15515	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
IUJ49_15520	COG3850	Histidine kinase
IUJ49_15525	COG2197	response regulator
IUJ49_15555	COG0121	glutamine amidotransferase
IUJ49_15560	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
IUJ49_15565	COG1960	acyl-CoA dehydrogenase activity
IUJ49_15570	COG3437	response regulator, receiver
IUJ49_15570	COG0784	Response regulator, receiver
IUJ49_15585	COG0328	RNA-DNA hybrid ribonuclease activity
IUJ49_15590	COG2226	methyltransferase
IUJ49_15595	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
IUJ49_15600	COG1388	LysM domain
IUJ49_15600	COG0741	lytic transglycosylase activity
IUJ49_15605	COG3021	interspecies interaction between organisms
IUJ49_15615	COG1607	acyl-coa hydrolase
IUJ49_15630	COG0741	lytic transglycosylase activity
IUJ49_15640	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
IUJ49_15665	COG0729	surface antigen
IUJ49_15675	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
IUJ49_15680	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
IUJ49_15690	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
IUJ49_15700	COG4134	Bacterial extracellular solute-binding protein
IUJ49_15710	COG4136	ATPase activity
IUJ49_15715	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
IUJ49_15720	COG2951	lytic endotransglycosylase activity
IUJ49_15725	COG1846	Transcriptional regulator
IUJ49_15735	COG0033	Phosphoglucomutase
IUJ49_15740	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
IUJ49_15745	COG0596	Alpha beta hydrolase
IUJ49_15760	COG0716	FMN binding
IUJ49_15770	COG0735	belongs to the Fur family
IUJ49_15775	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
IUJ49_15785	COG2190	(PTS) system
IUJ49_15785	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
IUJ49_15785	COG1263	PTS System
IUJ49_15790	COG0363	glucosamine-6-phosphate deaminase activity
IUJ49_15795	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
IUJ49_15800	COG1846	Transcriptional regulator
IUJ49_15800	COG1940	carbohydrate kinase activity
IUJ49_15805	COG2194	sulfuric ester hydrolase activity
IUJ49_15810	COG0217	transcriptional regulatory protein
IUJ49_15815	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
IUJ49_15820	COG1801	Protein of unknown function DUF72
IUJ49_15825	COG4106	trans-aconitate 2-methyltransferase activity
IUJ49_15830	COG0500	methyltransferase
IUJ49_15850	COG0450	alkyl hydroperoxide reductase
IUJ49_15855	COG0583	DNA-binding transcription factor activity
IUJ49_15865	COG0791	NLP P60 protein
IUJ49_15880	COG1309	transcriptional regulator
IUJ49_15920	COG0534	Mate efflux family protein
IUJ49_15940	COG2366	antibiotic biosynthetic process
IUJ49_15945	COG0674	pyruvate-flavodoxin oxidoreductase activity
IUJ49_15945	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
IUJ49_15945	COG1013	pyruvate-flavodoxin oxidoreductase activity
IUJ49_15945	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
IUJ49_15955	COG0633	Ferredoxin
IUJ49_15955	COG0633	Ferredoxin
IUJ49_15955	COG3217	Mosc domain protein beta barrel domain protein
IUJ49_15955	COG3217	Mosc domain protein beta barrel domain protein
IUJ49_15965	COG0501	Belongs to the peptidase M48B family
IUJ49_15970	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
IUJ49_15975	COG1073	alpha beta
IUJ49_15975	COG2226	methyltransferase
IUJ49_15980	COG0156	8-amino-7-oxononanoate synthase activity
IUJ49_15985	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
IUJ49_16005	COG0017	Asparaginyl-tRNA synthetase
IUJ49_16010	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
IUJ49_16025	COG3069	C4-dicarboxylate transmembrane transporter activity
IUJ49_16035	COG0583	DNA-binding transcription factor activity
IUJ49_16040	COG1393	Belongs to the ArsC family
IUJ49_16045	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
IUJ49_16050	COG1876	peptidase activity
IUJ49_16060	COG3263	regulation of cellular component size
IUJ49_16070	COG3263	regulation of cellular component size
IUJ49_16080	COG1280	lysine exporter protein (LysE YggA)
IUJ49_16110	COG0564	pseudouridine synthase activity
IUJ49_16120	COG1454	alcohol dehydrogenase
IUJ49_16125	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
IUJ49_16130	COG0702	epimerase
IUJ49_16135	COG2914	Belongs to the UPF0125 (RnfH) family
IUJ49_16140	COG2867	negative regulation of translational initiation
IUJ49_16145	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
IUJ49_16180	COG0583	DNA-binding transcription factor activity
IUJ49_16185	COG3048	D-serine ammonia-lyase activity
IUJ49_16195	COG0538	isocitrate dehydrogenase activity
IUJ49_16200	COG2207	Transcriptional regulator
IUJ49_16220	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
IUJ49_16235	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
IUJ49_16240	COG1263	PTS System
IUJ49_16240	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
IUJ49_16245	COG1609	Transcriptional regulator
IUJ49_16255	COG0456	acetyltransferase
IUJ49_16275	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
IUJ49_16275	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
IUJ49_16275	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
IUJ49_16280	COG5599	Phosphatase
IUJ49_16295	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
IUJ49_16295	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
IUJ49_16295	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
IUJ49_16305	COG1187	pseudouridine synthase activity
IUJ49_16315	COG0482	sulfurtransferase activity
IUJ49_16320	COG2915	High frequency lysogenization protein hflD homolog
IUJ49_16325	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
IUJ49_16330	COG2850	peptidyl-arginine hydroxylation
IUJ49_16340	COG3153	acetyltransferase
IUJ49_16350	COG0625	glutathione transferase activity
IUJ49_16355	COG0259	pyridoxamine-phosphate oxidase activity
IUJ49_16370	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
IUJ49_16370	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
IUJ49_16375	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
IUJ49_16390	COG4235	cytochrome complex assembly
IUJ49_16390	COG3088	subunit of a heme lyase
IUJ49_16395	COG4235	cytochrome complex assembly
IUJ49_16395	COG3088	subunit of a heme lyase
IUJ49_16400	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
IUJ49_16405	COG1138	Cytochrome C-type biogenesis protein
IUJ49_16410	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
IUJ49_16415	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
IUJ49_16420	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
IUJ49_16425	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
IUJ49_16440	COG0835	chemotaxis
IUJ49_16455	COG1360	Flagellar Motor Protein
IUJ49_16460	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
IUJ49_16465	COG2201	protein-glutamate methylesterase activity
IUJ49_16470	COG0643	Histidine kinase
IUJ49_16470	COG0784	Response regulator, receiver
IUJ49_16470	COG2198	Histidine kinase
IUJ49_16475	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
IUJ49_16500	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
IUJ49_16510	COG1684	flagellar biosynthetic protein fliR
IUJ49_16565	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
IUJ49_16575	COG1677	Flagellar hook-basal body complex protein FliE
IUJ49_16590	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
IUJ49_16610	COG1737	Transcriptional regulator
IUJ49_16615	COG0469	pyruvate kinase activity
IUJ49_16625	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
IUJ49_16630	COG1960	acyl-CoA dehydrogenase activity
IUJ49_16640	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
IUJ49_16680	COG0243	molybdopterin cofactor binding
IUJ49_16685	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
IUJ49_16690	COG0583	DNA-binding transcription factor activity
IUJ49_16725	COG1454	alcohol dehydrogenase
IUJ49_16725	COG1012	belongs to the aldehyde dehydrogenase family
IUJ49_16735	COG1012	belongs to the aldehyde dehydrogenase family
IUJ49_16735	COG1454	alcohol dehydrogenase
IUJ49_16740	COG1882	Formate acetyltransferase
IUJ49_16745	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
IUJ49_16755	COG4869	propanediol catabolic process
IUJ49_16780	COG1376	ErfK ybiS ycfS ynhG family protein
IUJ49_16780	COG1388	LysM domain
IUJ49_16795	COG3129	Specifically methylates the adenine in position 1618 of 23S rRNA
IUJ49_16800	COG0791	NLP P60 protein
IUJ49_16805	COG2091	lysine biosynthetic process via aminoadipic acid
IUJ49_16810	COG3118	belongs to the thioredoxin family
IUJ49_16820	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
IUJ49_16825	COG0788	formyltetrahydrofolate deformylase activity
IUJ49_16835	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
IUJ49_16855	COG0366	Alpha amylase catalytic
IUJ49_16860	COG0739	heme binding
IUJ49_16860	COG0741	lytic transglycosylase activity
IUJ49_16860	COG1196	nuclear chromosome segregation
IUJ49_16865	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
IUJ49_16870	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
IUJ49_16880	COG0673	inositol 2-dehydrogenase activity
IUJ49_16930	COG1032	radical SAM domain protein
IUJ49_16940	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
IUJ49_16945	COG1566	PFAM secretion protein HlyD family protein
IUJ49_16955	COG1752	Esterase of the alpha-beta hydrolase superfamily
IUJ49_16960	COG0733	neurotransmitter:sodium symporter activity
IUJ49_16990	COG0281	malic enzyme
IUJ49_17000	COG0534	Mate efflux family protein
IUJ49_17015	COG2233	PERMEase
IUJ49_17020	COG0095	Lipoate-protein ligase
IUJ49_17025	COG1115	amino acid carrier protein
IUJ49_17030	COG0019	diaminopimelate decarboxylase activity
IUJ49_17040	COG0678	peroxiredoxin activity
IUJ49_17050	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
IUJ49_17070	COG1131	(ABC) transporter
IUJ49_17075	COG0545	Peptidyl-prolyl cis-trans isomerase
IUJ49_17085	COG3142	Participates in the control of copper homeostasis
IUJ49_17110	COG5002	protein histidine kinase activity
IUJ49_17115	COG0745	RESPONSE REGULATOR receiver
IUJ49_17120	COG0346	lactoylglutathione lyase activity
IUJ49_17125	COG1804	L-carnitine dehydratase bile acid-inducible protein F
IUJ49_17130	COG1960	acyl-CoA dehydrogenase activity
IUJ49_17135	COG3284	Transcriptional regulator
IUJ49_17150	COG0697	spore germination
IUJ49_17170	COG4565	transcriptional regulatory protein
IUJ49_17175	COG3290	protein histidine kinase activity
IUJ49_17180	COG0281	malic enzyme
IUJ49_17190	COG1846	Transcriptional regulator
IUJ49_17195	COG1566	PFAM secretion protein HlyD family protein
IUJ49_17225	COG0602	queuosine metabolic process
IUJ49_17230	COG1328	CTP reductase activity
IUJ49_17240	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
IUJ49_17245	COG3115	cell septum assembly
IUJ49_17250	COG1196	nuclear chromosome segregation
IUJ49_17260	COG2860	membrane
IUJ49_17270	COG3108	Peptidase M15
IUJ49_17275	COG2989	Protein conserved in bacteria
IUJ49_17290	COG0463	Glycosyl transferase, family 2
IUJ49_17305	COG0366	Alpha amylase catalytic
IUJ49_17345	COG3706	GGDEF domain
IUJ49_17355	COG3590	peptidase
IUJ49_17365	COG0488	(ABC) transporter
IUJ49_17375	COG0531	amino acid
IUJ49_17390	COG0814	amino acid
IUJ49_17405	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
IUJ49_17410	COG1982	Orn Lys Arg decarboxylase major
IUJ49_17415	COG0531	amino acid
IUJ49_17420	COG3710	Transcriptional regulator
IUJ49_17425	COG0825	malonyl-CoA metabolic process
IUJ49_17435	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
IUJ49_17440	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
IUJ49_17445	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
IUJ49_17450	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
IUJ49_17455	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
IUJ49_17470	COG0750	zinc metalloprotease
IUJ49_17475	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
IUJ49_17480	COG0575	Belongs to the CDS family
IUJ49_17485	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
IUJ49_17490	COG0233	cytoplasmic translational termination
IUJ49_17495	COG0528	UMP kinase activity
IUJ49_17500	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
IUJ49_17505	COG0052	Belongs to the universal ribosomal protein uS2 family
IUJ49_17510	COG0024	Methionine aminopeptidase
IUJ49_17515	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
IUJ49_17520	COG2171	N-acyltransferase activity
IUJ49_17530	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
IUJ49_17530	COG1263	PTS System
IUJ49_17550	COG0564	pseudouridine synthase activity
IUJ49_17555	COG3098	single-species biofilm formation
IUJ49_17580	COG5595	Zn-ribbon-containing, possibly nucleic-acid-binding protein (DUF2310)
IUJ49_17590	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
IUJ49_17590	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
IUJ49_17605	COG1611	Belongs to the LOG family
IUJ49_17610	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
IUJ49_17615	COG0473	3-isopropylmalate dehydrogenase activity
IUJ49_17625	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
IUJ49_17630	COG2363	Small membrane protein
IUJ49_17640	COG0583	DNA-binding transcription factor activity
IUJ49_17645	COG0840	transmembrane signaling receptor activity
IUJ49_17650	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
IUJ49_17665	COG1477	protein flavinylation
IUJ49_17670	COG2871	sodium ion transport
IUJ49_17675	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
IUJ49_17680	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
IUJ49_17685	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
IUJ49_17690	COG1805	sodium ion transport
IUJ49_17695	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
IUJ49_17700	COG0271	Belongs to the BolA IbaG family
IUJ49_17705	COG2813	Specifically methylates the guanine in position
IUJ49_17715	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
IUJ49_17725	COG2211	Major facilitator Superfamily
IUJ49_17730	COG3248	Nucleoside-binding outer membrane protein
IUJ49_17735	COG1666	GTP binding
IUJ49_17740	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
IUJ49_17745	COG0693	protein deglycase activity
IUJ49_17785	COG4104	PAAR repeat-containing protein
IUJ49_17800	COG2771	luxR family
IUJ49_17810	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
IUJ49_17810	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
IUJ49_17815	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
IUJ49_17825	COG1151	hydroxylamine reductase activity
IUJ49_17830	COG0783	Belongs to the Dps family
IUJ49_17855	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
IUJ49_17870	COG4221	oxidoreductase activity
IUJ49_17880	COG0415	Belongs to the DNA photolyase family
IUJ49_17885	COG0789	Transcriptional regulator
IUJ49_17890	COG3272	Protein of unknown function (DUF1722)
IUJ49_17920	COG0077	Prephenate dehydratase
IUJ49_17920	COG1605	Chorismate mutase
IUJ49_17955	COG0840	transmembrane signaling receptor activity
IUJ49_17965	COG0300	oxidoreductase activity
IUJ49_17990	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
IUJ49_18020	COG0826	peptidase U32
IUJ49_18025	COG1280	lysine exporter protein (LysE YggA)
IUJ49_18035	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
IUJ49_18040	COG0840	transmembrane signaling receptor activity
IUJ49_18055	COG2198	Histidine kinase
IUJ49_18055	COG0643	Histidine kinase
IUJ49_18065	COG0835	chemotaxis
IUJ49_18070	COG0840	transmembrane signaling receptor activity
IUJ49_18080	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
IUJ49_18085	COG2201	protein-glutamate methylesterase activity
IUJ49_18090	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
IUJ49_18115	COG2199	diguanylate cyclase activity
IUJ49_18115	COG2200	EAL domain
IUJ49_18115	COG2203	Gaf domain
IUJ49_18120	COG0826	peptidase U32
IUJ49_18125	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
IUJ49_18130	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
IUJ49_18135	COG0305	Participates in initiation and elongation during chromosome replication
IUJ49_18145	COG2200	EAL domain
IUJ49_18150	COG0737	Belongs to the 5'-nucleotidase family
IUJ49_18170	COG2204	response regulator
IUJ49_18175	COG0545	Peptidyl-prolyl cis-trans isomerase
IUJ49_18190	COG1047	Peptidyl-prolyl cis-trans
IUJ49_18195	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
IUJ49_18205	COG0835	chemotaxis
IUJ49_18205	COG0784	Response regulator, receiver
IUJ49_18210	COG0429	hydrolase of the alpha beta-hydrolase fold
IUJ49_18215	COG5001	Diguanylate cyclase
IUJ49_18215	COG4251	negative regulation of phosphorylation
IUJ49_18215	COG3706	GGDEF domain
IUJ49_18215	COG2203	Gaf domain
IUJ49_18220	COG3089	Belongs to the UPF0270 family
IUJ49_18230	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
IUJ49_18235	COG0463	Glycosyl transferase, family 2
IUJ49_18240	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
IUJ49_18240	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
IUJ49_18245	COG0726	polysaccharide deacetylase
IUJ49_18250	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
IUJ49_18255	COG2076	Multidrug Resistance protein
IUJ49_18260	COG2076	Multidrug Resistance protein
IUJ49_18265	COG3954	Phosphoribulokinase
IUJ49_18280	COG1765	OsmC-like protein
IUJ49_18295	COG3397	chitin binding
IUJ49_18310	COG2202	Pas domain
IUJ49_18310	COG2205	protein histidine kinase activity
IUJ49_18320	COG3655	Transcriptional regulator
IUJ49_18325	COG2814	Major facilitator Superfamily
IUJ49_18330	COG4771	TonB-dependent receptor
IUJ49_18350	COG0748	coenzyme F420 binding
IUJ49_18355	COG3721	Heme iron utilization protein
IUJ49_18365	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IUJ49_18390	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
IUJ49_18395	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
IUJ49_18400	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
IUJ49_18420	COG0741	lytic transglycosylase activity
IUJ49_18425	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
IUJ49_18440	COG0488	(ABC) transporter
IUJ49_18450	COG2252	PERMEase
IUJ49_18455	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
IUJ49_18460	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
IUJ49_18465	COG3178	'Phosphotransferase
IUJ49_18470	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
IUJ49_18480	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
IUJ49_18485	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
IUJ49_18490	COG2967	ApaG domain
IUJ49_18495	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
IUJ49_18505	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IUJ49_18510	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
IUJ49_18525	COG0318	PFAM AMP-dependent synthetase and ligase
IUJ49_18530	COG3314	Sporulation integral membrane protein YlbJ
IUJ49_18535	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
IUJ49_18540	COG0211	Belongs to the bacterial ribosomal protein bL27 family
IUJ49_18545	COG0261	This protein binds to 23S rRNA in the presence of protein L20
IUJ49_18550	COG0142	geranyltranstransferase activity
IUJ49_18555	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
IUJ49_18560	COG0330	HflC and HflK could
IUJ49_18565	COG0330	HflC and HflK could
IUJ49_18570	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
IUJ49_18575	COG1923	regulation of RNA biosynthetic process
IUJ49_18580	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
IUJ49_18585	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
IUJ49_18595	COG0802	atpase or kinase
IUJ49_18600	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
IUJ49_18600	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
IUJ49_18605	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
IUJ49_18620	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
IUJ49_18625	COG2011	ABC-type metal ion transport system permease component
IUJ49_18630	COG1464	Belongs to the NlpA lipoprotein family
IUJ49_18640	COG0840	transmembrane signaling receptor activity
IUJ49_18665	COG5002	protein histidine kinase activity
IUJ49_18665	COG2198	Histidine kinase
IUJ49_18665	COG0784	Response regulator, receiver
IUJ49_18685	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
IUJ49_18700	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
IUJ49_18705	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
IUJ49_18715	COG2716	regulation of RNA biosynthetic process
IUJ49_18720	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
IUJ49_18725	COG3013	Belongs to the UPF0304 family
IUJ49_18735	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
IUJ49_18740	COG0280	phosphate acetyltransferase
IUJ49_18740	COG0857	belongs to the CobB CobQ family
IUJ49_18750	COG0028	Belongs to the TPP enzyme family
IUJ49_18760	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
IUJ49_18765	COG0671	phosphoesterase, PA-phosphatase related
IUJ49_18775	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
IUJ49_18780	COG0473	3-isopropylmalate dehydrogenase activity
IUJ49_18785	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
IUJ49_18790	COG0066	3-isopropylmalate dehydratase activity
IUJ49_18805	COG4143	(ABC) transporter
IUJ49_18815	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
IUJ49_18820	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
IUJ49_18860	COG0316	Belongs to the HesB IscA family
IUJ49_18870	COG0038	chloride channel
IUJ49_18875	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
IUJ49_18890	COG0671	phosphoesterase, PA-phosphatase related
IUJ49_18900	COG3437	response regulator, receiver
IUJ49_18900	COG0784	Response regulator, receiver
IUJ49_18910	COG2076	Multidrug Resistance protein
IUJ49_18920	COG0346	lactoylglutathione lyase activity
IUJ49_18925	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
IUJ49_18930	COG1643	Atp-dependent helicase
IUJ49_18940	COG1489	DNA binding
IUJ49_18945	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
IUJ49_18950	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
IUJ49_18965	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
IUJ49_18970	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
IUJ49_18990	COG1924	4 iron, 4 sulfur cluster binding
IUJ49_18995	COG1775	2-hydroxyglutaryl-CoA dehydratase, D-component
IUJ49_19000	COG0842	Transport permease protein
IUJ49_19005	COG1131	(ABC) transporter
IUJ49_19020	COG0163	prenyltransferase activity
IUJ49_19025	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
IUJ49_19030	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
IUJ49_19045	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
IUJ49_19060	COG1136	(ABC) transporter
IUJ49_19080	COG0840	transmembrane signaling receptor activity
IUJ49_19085	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
IUJ49_19090	COG0529	Catalyzes the synthesis of activated sulfate
IUJ49_19095	COG3273	potassium ion transport
IUJ49_19095	COG0471	metal ion transport
IUJ49_19100	COG2895	sulfate adenylyltransferase (ATP) activity
IUJ49_19105	COG0175	sulfate reduction
IUJ49_19110	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
IUJ49_19110	COG1648	precorrin-2 dehydrogenase activity
IUJ49_19115	COG0330	HflC and HflK could
IUJ49_19120	COG1585	Membrane protein implicated in regulation of membrane protease activity
IUJ49_19125	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
IUJ49_19125	COG0517	IMP dehydrogenase activity
IUJ49_19130	COG0488	(ABC) transporter
IUJ49_19140	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
IUJ49_19145	COG0583	DNA-binding transcription factor activity
IUJ49_19180	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
IUJ49_19190	COG0668	transmembrane transport
IUJ49_19200	COG2731	YhcH YjgK YiaL family protein
IUJ49_19215	COG1794	racemase activity, acting on amino acids and derivatives
IUJ49_19230	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
IUJ49_19255	COG0733	neurotransmitter:sodium symporter activity
IUJ49_19265	COG0733	neurotransmitter:sodium symporter activity
IUJ49_19280	COG0561	phosphatase activity
IUJ49_19310	COG1846	Transcriptional regulator
IUJ49_19315	COG1764	response to oxidative stress
IUJ49_19320	COG2130	NADP-dependent
IUJ49_19325	COG1051	belongs to the nudix hydrolase family
IUJ49_19345	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
IUJ49_19350	COG1640	4-alpha-glucanotransferase
IUJ49_19355	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
IUJ49_19360	COG0676	glucose-6-phosphate 1-epimerase activity
IUJ49_19365	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
IUJ49_19370	COG0840	transmembrane signaling receptor activity
IUJ49_19445	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
IUJ49_19450	COG2885	chlorophyll binding
IUJ49_19455	COG0823	Involved in the tonB-independent uptake of proteins
IUJ49_19470	COG0811	peptide transport
IUJ49_19475	COG0824	Thioesterase
IUJ49_19480	COG3790	cyd operon protein YbgE
IUJ49_19485	COG4890	Cyd operon protein YbgT
IUJ49_19490	COG1294	oxidase, subunit
IUJ49_19495	COG1271	oxidase subunit
IUJ49_19500	COG2255	four-way junction helicase activity
IUJ49_19505	COG0632	four-way junction helicase activity
IUJ49_19510	COG0840	transmembrane signaling receptor activity
IUJ49_19515	COG0442	prolyl-tRNA aminoacylation
IUJ49_19520	COG4221	oxidoreductase activity
IUJ49_19535	COG1024	Enoyl-CoA hydratase
IUJ49_19555	COG4166	transmembrane transport
IUJ49_19570	COG1872	DUF167
IUJ49_19575	COG0762	integral membrane protein
IUJ49_19580	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
IUJ49_19585	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
IUJ49_19600	COG3022	response to hydroperoxide
IUJ49_19605	COG0513	Belongs to the DEAD box helicase family
IUJ49_19610	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
IUJ49_19635	COG0735	belongs to the Fur family
IUJ49_19640	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
IUJ49_19655	COG0776	regulation of translation
IUJ49_19665	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
IUJ49_19690	COG0560	Phosphoserine phosphatase
IUJ49_19700	COG5002	protein histidine kinase activity
IUJ49_19700	COG3447	MASE1 domain protein
IUJ49_19700	COG5001	Diguanylate cyclase
IUJ49_19705	COG0813	purine-nucleoside phosphorylase activity
IUJ49_19710	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
IUJ49_19715	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
IUJ49_19720	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
IUJ49_19730	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
IUJ49_19735	COG0084	hydrolase, TatD family'
IUJ49_19740	COG2165	general secretion pathway protein
IUJ49_19750	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
IUJ49_19755	COG0004	ammonium transporteR
IUJ49_19760	COG4974	Belongs to the 'phage' integrase family
IUJ49_19770	COG2932	Transcriptional regulator
IUJ49_19850	COG4695	Portal protein
IUJ49_19985	COG0795	lipopolysaccharide-transporting ATPase activity
IUJ49_19990	COG0795	lipopolysaccharide-transporting ATPase activity
IUJ49_19995	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
IUJ49_20000	COG2927	DNA polymerase III (CHI subunit)
IUJ49_20005	COG0525	valine-tRNA ligase activity
IUJ49_20010	COG1253	flavin adenine dinucleotide binding
IUJ49_20015	COG0586	Pfam SNARE associated Golgi protein
IUJ49_20020	COG1686	Belongs to the peptidase S11 family
IUJ49_20055	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
IUJ49_20060	COG0527	aspartate kinase activity
IUJ49_20065	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
IUJ49_20075	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
IUJ49_20080	COG1546	Belongs to the CinA family
IUJ49_20085	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
IUJ49_20105	COG3068	Protein conserved in bacteria
IUJ49_20115	COG0739	heme binding
IUJ49_20135	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
IUJ49_20140	COG1121	(ABC) transporter
IUJ49_20145	COG1108	ABC-type Mn2 Zn2 transport systems permease components
IUJ49_20150	COG0583	DNA-binding transcription factor activity
IUJ49_20155	COG0697	spore germination
IUJ49_20160	COG1573	uracil-dna glycosylase
IUJ49_20165	COG2962	Rard protein
IUJ49_20175	COG2827	Endonuclease containing a URI domain
IUJ49_20190	COG1842	Phage shock protein A
IUJ49_20195	COG0204	Acyl-transferase
IUJ49_20220	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
IUJ49_20265	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
IUJ49_20280	COG1289	transmembrane transporter activity
IUJ49_20285	COG1566	PFAM secretion protein HlyD family protein
IUJ49_20300	COG1051	belongs to the nudix hydrolase family
IUJ49_20305	COG3150	esterase
IUJ49_20315	COG3151	Protein conserved in bacteria
IUJ49_20320	COG0494	nUDIX hydrolase
IUJ49_20325	COG1538	Outer membrane efflux protein
IUJ49_20330	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
IUJ49_20330	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
IUJ49_20335	COG1560	Kdo2-lipid A biosynthetic process
IUJ49_20350	COG1392	Phosphate transport regulator
IUJ49_20355	COG0306	phosphate transporter
IUJ49_20360	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
IUJ49_20390	COG0583	DNA-binding transcription factor activity
IUJ49_20395	COG1380	Effector of murein hydrolase LrgA
IUJ49_20400	COG1346	cytolysis
IUJ49_20415	COG0617	tRNA 3'-terminal CCA addition
IUJ49_20420	COG3267	Type II secretory pathway component ExeA
IUJ49_20420	COG3409	Peptidoglycan-binding domain 1 protein
IUJ49_20430	COG1194	a g-specific adenine glycosylase
IUJ49_20435	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
IUJ49_20445	COG3111	PFAM Bacterial OB fold (BOF) protein
IUJ49_20450	COG3240	lipase activity
IUJ49_20460	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
IUJ49_20460	COG2885	chlorophyll binding
IUJ49_20465	COG3009	Protein conserved in bacteria
IUJ49_20470	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
IUJ49_20470	COG3008	intermembrane lipid transfer
IUJ49_20475	COG2995	paraquat-inducible protein a
IUJ49_20485	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
IUJ49_20495	COG5001	Diguanylate cyclase
IUJ49_20495	COG2203	Gaf domain
IUJ49_20495	COG3706	GGDEF domain
IUJ49_20495	COG4251	negative regulation of phosphorylation
IUJ49_20500	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
IUJ49_20505	COG2813	Specifically methylates the guanine in position
IUJ49_20510	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
IUJ49_20515	COG0297	glycogen (starch) synthase activity
IUJ49_20555	COG1757	Na H antiporter
IUJ49_20560	COG0583	DNA-binding transcription factor activity
IUJ49_20565	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
IUJ49_20570	COG3842	ATPase activity
IUJ49_20575	COG1176	ABC-type spermidine putrescine transport system, permease component I
IUJ49_20580	COG1177	transmembrane transport
IUJ49_20585	COG1012	belongs to the aldehyde dehydrogenase family
IUJ49_20595	COG5006	permease, DMT superfamily
IUJ49_20600	COG1522	sequence-specific DNA binding
IUJ49_20605	COG0110	maltose O-acetyltransferase activity
IUJ49_20610	COG0366	Alpha amylase catalytic
IUJ49_20615	COG1263	PTS System
IUJ49_20615	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
IUJ49_20635	COG0252	asparaginase activity
IUJ49_20650	COG1803	Methylglyoxal synthase
IUJ49_20675	COG1444	tRNA N-acetyltransferase activity
IUJ49_20690	COG0835	chemotaxis
IUJ49_20690	COG0784	Response regulator, receiver
IUJ49_20695	COG3314	Sporulation integral membrane protein YlbJ
IUJ49_20735	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
IUJ49_20740	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
IUJ49_20755	COG0477	Major facilitator Superfamily
IUJ49_20760	COG0523	cobalamin synthesis protein
IUJ49_20770	COG1280	lysine exporter protein (LysE YggA)
IUJ49_20780	COG2200	EAL domain
IUJ49_20785	COG1049	propionate catabolic process, 2-methylcitrate cycle
IUJ49_20790	COG1752	Esterase of the alpha-beta hydrolase superfamily
IUJ49_20795	COG0840	transmembrane signaling receptor activity
IUJ49_20800	COG0840	transmembrane signaling receptor activity
IUJ49_20810	COG5001	Diguanylate cyclase
IUJ49_20810	COG3447	MASE1 domain protein
IUJ49_20810	COG5002	protein histidine kinase activity
IUJ49_20815	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
IUJ49_20820	COG0508	dehydrogenase complex catalyzes the overall conversion of
IUJ49_20825	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
IUJ49_20830	COG2186	Transcriptional regulator
IUJ49_20855	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
IUJ49_20860	COG1459	type II secretion system
IUJ49_20875	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
IUJ49_20880	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
IUJ49_20885	COG0494	nUDIX hydrolase
IUJ49_20895	COG0653	protein targeting
IUJ49_20905	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
IUJ49_20910	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
IUJ49_20915	COG0849	cell division
IUJ49_20920	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
IUJ49_20925	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
IUJ49_20930	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
IUJ49_20935	COG0772	Belongs to the SEDS family
IUJ49_20940	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
IUJ49_20945	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
IUJ49_20950	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
IUJ49_20960	COG0768	penicillin binding
IUJ49_20965	COG3116	cell division
IUJ49_20970	COG0275	rRNA processing
IUJ49_20975	COG2001	Belongs to the MraZ family
IUJ49_20985	COG0741	lytic transglycosylase activity
IUJ49_20985	COG1388	LysM domain
IUJ49_20990	COG1360	Flagellar Motor Protein
IUJ49_20995	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
IUJ49_21000	COG1191	sigma factor activity
IUJ49_21025	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
IUJ49_21030	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
IUJ49_21050	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
IUJ49_21055	COG4786	Flagellar basal body rod
IUJ49_21055	COG1256	bacterial-type flagellum assembly
IUJ49_21065	COG1706	bacterial-type flagellum-dependent cell motility
IUJ49_21070	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
IUJ49_21075	COG4786	Flagellar basal body rod
IUJ49_21085	COG1749	Flagellar hook protein flgE
IUJ49_21100	COG1815	bacterial-type flagellum-dependent cell motility
IUJ49_21135	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
IUJ49_21145	COG1677	Flagellar hook-basal body complex protein FliE
IUJ49_21195	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
IUJ49_21200	COG3107	peptidoglycan biosynthetic process
IUJ49_21205	COG0792	nuclease activity
IUJ49_21210	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
IUJ49_21215	COG2823	Periplasmic or secreted lipoprotein
IUJ49_21220	COG2969	positive regulation of protein catabolic process
IUJ49_21225	COG0625	glutathione transferase activity
IUJ49_21230	COG2857	Cytochrome c1
IUJ49_21235	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
IUJ49_21240	COG0723	plastoquinol--plastocyanin reductase activity
IUJ49_21245	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
IUJ49_21250	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
IUJ49_21255	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
IUJ49_21265	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
IUJ49_21270	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
IUJ49_21300	COG3964	amidohydrolase
IUJ49_21315	COG3711	transcriptional antiterminator
IUJ49_21315	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
IUJ49_21320	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
IUJ49_21325	COG1660	Displays ATPase and GTPase activities
IUJ49_21330	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
IUJ49_21340	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
IUJ49_21345	COG1137	ATPase activity
IUJ49_21350	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
IUJ49_21355	COG3117	lipopolysaccharide transmembrane transporter activity
IUJ49_21360	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
IUJ49_21365	COG0517	IMP dehydrogenase activity
IUJ49_21365	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
IUJ49_21370	COG1127	ABC transporter
IUJ49_21375	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
IUJ49_21380	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
IUJ49_21385	COG2854	intermembrane phospholipid transfer
IUJ49_21395	COG5007	Belongs to the BolA IbaG family
IUJ49_21400	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
IUJ49_21405	COG0312	modulator of DNA gyrase
IUJ49_21410	COG3028	Belongs to the UPF0307 family
IUJ49_21420	COG2926	Belongs to the UPF0265 family
IUJ49_21450	COG1396	sequence-specific DNA binding
IUJ49_21455	COG3135	benzoate transporter
IUJ49_21480	COG0840	transmembrane signaling receptor activity
IUJ49_21485	COG3047	cAMP biosynthetic process
IUJ49_21495	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
IUJ49_21500	COG2197	response regulator
IUJ49_21505	COG0629	single-stranded DNA binding
IUJ49_21525	COG1278	Cold shock
IUJ49_21530	COG4771	TonB-dependent receptor
IUJ49_21535	COG5001	Diguanylate cyclase
IUJ49_21535	COG4251	negative regulation of phosphorylation
IUJ49_21535	COG3706	GGDEF domain
IUJ49_21535	COG2203	Gaf domain
IUJ49_21585	COG0346	lactoylglutathione lyase activity
IUJ49_21600	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
IUJ49_21605	COG1074	ATP-dependent DNA helicase activity
IUJ49_21610	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
IUJ49_21615	COG2259	Doxx family
IUJ49_21620	COG1741	Belongs to the pirin family
IUJ49_21630	COG0583	DNA-binding transcription factor activity
IUJ49_21655	COG1176	ABC-type spermidine putrescine transport system, permease component I
IUJ49_21665	COG3842	ATPase activity
IUJ49_21675	COG2199	diguanylate cyclase activity
IUJ49_21675	COG2203	Gaf domain
IUJ49_21695	COG1247	-acetyltransferase
IUJ49_21700	COG0753	catalase activity
IUJ49_21725	COG0494	nUDIX hydrolase
IUJ49_21730	COG0628	permease
IUJ49_21735	COG4221	oxidoreductase activity
IUJ49_21740	COG2957	Belongs to the agmatine deiminase family
IUJ49_21750	COG3284	Transcriptional regulator
IUJ49_21765	COG1461	Dihydroxyacetone kinase
IUJ49_21770	COG2376	Dihydroxyacetone kinase
IUJ49_21775	COG2252	PERMEase
IUJ49_21815	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
IUJ49_21820	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
IUJ49_21825	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
IUJ49_21830	COG0049	tRNA binding
IUJ49_21835	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
IUJ49_21840	COG2168	tRNA wobble position uridine thiolation
IUJ49_21845	COG2923	Belongs to the DsrF TusC family
IUJ49_21855	COG0251	oxidation-reduction process
IUJ49_21860	COG2964	Protein conserved in bacteria
IUJ49_21865	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
IUJ49_21870	COG0085	RNA polymerase activity
IUJ49_21875	COG0222	ribosome binding
IUJ49_21880	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
IUJ49_21885	COG0081	regulation of translation
IUJ49_21890	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
IUJ49_21895	COG0250	Participates in transcription elongation, termination and antitermination
IUJ49_21910	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis