locus-tag	class	description
WP7S18E06_00010	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
WP7S18E06_00020	COG0592	DNA-directed DNA polymerase activity
WP7S18E06_00030	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
WP7S18E06_00070	COG2378	regulation of single-species biofilm formation
WP7S18E06_00080	COG0071	Belongs to the small heat shock protein (HSP20) family
WP7S18E06_00090	COG0071	Belongs to the small heat shock protein (HSP20) family
WP7S18E06_00100	COG3977	Valine--pyruvate aminotransferase
WP7S18E06_00130	COG2814	Major facilitator Superfamily
WP7S18E06_00140	COG0745	RESPONSE REGULATOR receiver
WP7S18E06_00150	COG2205	protein histidine kinase activity
WP7S18E06_00210	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
WP7S18E06_00220	COG4191	Histidine kinase
WP7S18E06_00220	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
WP7S18E06_00230	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
WP7S18E06_00240	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
WP7S18E06_00250	COG1309	transcriptional regulator
WP7S18E06_00270	COG0469	pyruvate kinase activity
WP7S18E06_00280	COG0469	pyruvate kinase activity
WP7S18E06_00290	COG2271	Major facilitator Superfamily
WP7S18E06_00340	COG0561	phosphatase activity
WP7S18E06_00350	COG2267	carboxylic ester hydrolase activity
WP7S18E06_00360	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
WP7S18E06_00370	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
WP7S18E06_00380	COG1758	RNA polymerase activity
WP7S18E06_00400	COG0859	PFAM glycosyl transferase family 9
WP7S18E06_00410	COG3642	lipopolysaccharide core region biosynthetic process
WP7S18E06_00490	COG0589	response to stress
WP7S18E06_00500	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
WP7S18E06_00510	COG3706	GGDEF domain
WP7S18E06_00520	COG1528	Iron-storage protein
WP7S18E06_00530	COG2081	HI0933 family
WP7S18E06_00540	COG2223	nitrite transmembrane transporter activity
WP7S18E06_00580	COG3188	usher protein
WP7S18E06_00640	COG2205	protein histidine kinase activity
WP7S18E06_00640	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
WP7S18E06_00660	COG3275	phosphorelay sensor kinase activity
WP7S18E06_00670	COG3279	Response regulator of the LytR AlgR family
WP7S18E06_00680	COG2223	nitrite transmembrane transporter activity
WP7S18E06_00690	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
WP7S18E06_00700	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
WP7S18E06_00730	COG0583	DNA-binding transcription factor activity
WP7S18E06_00740	COG4206	TonB-dependent receptor
WP7S18E06_00750	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
WP7S18E06_00770	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
WP7S18E06_00780	COG2166	iron-sulfur cluster assembly
WP7S18E06_00790	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
WP7S18E06_00800	COG0210	DNA helicase
WP7S18E06_00820	COG3245	cytochrome
WP7S18E06_00830	COG1063	alcohol dehydrogenase
WP7S18E06_00840	COG0156	8-amino-7-oxononanoate synthase activity
WP7S18E06_00860	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
WP7S18E06_00890	COG3306	glycosyltransferase involved in LPS biosynthesis
WP7S18E06_00930	COG1561	YicC-like family, N-terminal region
WP7S18E06_00940	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
WP7S18E06_00950	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
WP7S18E06_00970	COG0789	Transcriptional regulator
WP7S18E06_00980	COG3706	GGDEF domain
WP7S18E06_00980	COG4251	negative regulation of phosphorylation
WP7S18E06_00980	COG5001	Diguanylate cyclase
WP7S18E06_00980	COG2203	Gaf domain
WP7S18E06_00990	COG3084	Protein conserved in bacteria
WP7S18E06_01010	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
WP7S18E06_01020	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
WP7S18E06_01050	COG1335	isochorismatase
WP7S18E06_01070	COG1683	Conserved Protein
WP7S18E06_01080	COG0204	Acyl-transferase
WP7S18E06_01090	COG0204	Acyl-transferase
WP7S18E06_01100	COG0606	chelatase, subunit chli
WP7S18E06_01120	COG3978	acetolactate synthase activity
WP7S18E06_01140	COG0129	dihydroxy-acid dehydratase activity
WP7S18E06_01180	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
WP7S18E06_01190	COG0254	rRNA binding
WP7S18E06_01200	COG0702	epimerase
WP7S18E06_01210	COG0281	malic enzyme
WP7S18E06_01230	COG2205	protein histidine kinase activity
WP7S18E06_01240	COG0745	RESPONSE REGULATOR receiver
WP7S18E06_01250	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
WP7S18E06_01280	COG0366	Alpha amylase catalytic
WP7S18E06_01310	COG0443	Heat shock 70 kDa protein
WP7S18E06_01320	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
WP7S18E06_01330	COG3045	CreA protein
WP7S18E06_01370	COG0174	glutamine synthetase
WP7S18E06_01410	COG3842	ATPase activity
WP7S18E06_01420	COG1176	ABC-type spermidine putrescine transport system, permease component I
WP7S18E06_01430	COG1177	transmembrane transport
WP7S18E06_01440	COG2258	MOSC domain
WP7S18E06_01460	COG2050	protein possibly involved in aromatic compounds catabolism
WP7S18E06_01470	COG0514	ATP-dependent DNA helicase (RecQ)
WP7S18E06_01490	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
WP7S18E06_01510	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
WP7S18E06_01520	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
WP7S18E06_01540	COG2239	Acts as a magnesium transporter
WP7S18E06_01550	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
WP7S18E06_01550	COG1648	precorrin-2 dehydrogenase activity
WP7S18E06_01560	COG2116	formate transmembrane transporter activity
WP7S18E06_01580	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
WP7S18E06_01590	COG0842	Transport permease protein
WP7S18E06_01600	COG0842	Transport permease protein
WP7S18E06_01610	COG1131	(ABC) transporter
WP7S18E06_01620	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
WP7S18E06_01650	COG0477	Major facilitator Superfamily
WP7S18E06_01660	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
WP7S18E06_01670	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
WP7S18E06_01710	COG1595	DNA-templated transcription, initiation
WP7S18E06_01720	COG3806	Anti-sigma factor
WP7S18E06_01730	COG1968	undecaprenyl-diphosphatase activity
WP7S18E06_01740	COG0667	Aldo Keto reductase
WP7S18E06_01750	COG2017	converts alpha-aldose to the beta-anomer
WP7S18E06_01760	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
WP7S18E06_01790	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
WP7S18E06_01800	COG1609	Transcriptional regulator
WP7S18E06_01810	COG3250	beta-galactosidase activity
WP7S18E06_01850	COG0840	transmembrane signaling receptor activity
WP7S18E06_01910	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
WP7S18E06_01920	COG1288	antiporter activity
WP7S18E06_01930	COG1438	arginine binding
WP7S18E06_01940	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
WP7S18E06_01950	COG0540	Belongs to the ATCase OTCase family
WP7S18E06_01970	COG0688	phosphatidylethanolamine metabolic process
WP7S18E06_01990	COG3040	lipid binding
WP7S18E06_02000	COG2207	Transcriptional regulator
WP7S18E06_02010	COG1979	alcohol dehydrogenase
WP7S18E06_02020	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
WP7S18E06_02030	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
WP7S18E06_02050	COG3681	Belongs to the UPF0597 family
WP7S18E06_02070	COG0446	pyridine nucleotide-disulphide oxidoreductase
WP7S18E06_02080	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
WP7S18E06_02090	COG0564	pseudouridine synthase activity
WP7S18E06_02110	COG0542	response to heat
WP7S18E06_02120	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
WP7S18E06_02130	COG2502	aspartate--ammonia ligase
WP7S18E06_02140	COG1522	sequence-specific DNA binding
WP7S18E06_02160	COG5413	integral membrane protein
WP7S18E06_02210	COG2205	protein histidine kinase activity
WP7S18E06_02230	COG2204	response regulator
WP7S18E06_02270	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
WP7S18E06_02300	COG0745	RESPONSE REGULATOR receiver
WP7S18E06_02310	COG2205	protein histidine kinase activity
WP7S18E06_02330	COG0243	molybdopterin cofactor binding
WP7S18E06_02340	COG3005	denitrification pathway
WP7S18E06_02350	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
WP7S18E06_02390	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
WP7S18E06_02400	COG0569	domain protein
WP7S18E06_02410	COG0812	UDP-N-acetylmuramate dehydrogenase activity
WP7S18E06_02440	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
WP7S18E06_02460	COG0250	Participates in transcription elongation, termination and antitermination
WP7S18E06_02470	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
WP7S18E06_02480	COG0081	regulation of translation
WP7S18E06_02490	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
WP7S18E06_02500	COG0222	ribosome binding
WP7S18E06_02510	COG0085	RNA polymerase activity
WP7S18E06_02520	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
WP7S18E06_02540	COG2964	Protein conserved in bacteria
WP7S18E06_02550	COG0251	oxidation-reduction process
WP7S18E06_02570	COG2923	Belongs to the DsrF TusC family
WP7S18E06_02580	COG2168	tRNA wobble position uridine thiolation
WP7S18E06_02590	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
WP7S18E06_02600	COG0049	tRNA binding
WP7S18E06_02610	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
WP7S18E06_02620	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
WP7S18E06_02630	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
WP7S18E06_02650	COG2252	PERMEase
WP7S18E06_02660	COG2376	Dihydroxyacetone kinase
WP7S18E06_02670	COG1461	Dihydroxyacetone kinase
WP7S18E06_02700	COG3284	Transcriptional regulator
WP7S18E06_02710	COG0583	DNA-binding transcription factor activity
WP7S18E06_02720	COG2957	Belongs to the agmatine deiminase family
WP7S18E06_02750	COG0628	permease
WP7S18E06_02760	COG0494	nUDIX hydrolase
WP7S18E06_02810	COG0753	catalase activity
WP7S18E06_02820	COG1247	-acetyltransferase
WP7S18E06_02860	COG2203	Gaf domain
WP7S18E06_02860	COG2199	diguanylate cyclase activity
WP7S18E06_02880	COG3842	ATPase activity
WP7S18E06_02900	COG1175	transmembrane transport
WP7S18E06_02950	COG0583	DNA-binding transcription factor activity
WP7S18E06_02970	COG1741	Belongs to the pirin family
WP7S18E06_02980	COG2259	Doxx family
WP7S18E06_02990	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
WP7S18E06_03000	COG1074	ATP-dependent DNA helicase activity
WP7S18E06_03010	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
WP7S18E06_03030	COG0346	lactoylglutathione lyase activity
WP7S18E06_03100	COG0745	RESPONSE REGULATOR receiver
WP7S18E06_03120	COG5001	Diguanylate cyclase
WP7S18E06_03120	COG4251	negative regulation of phosphorylation
WP7S18E06_03120	COG3706	GGDEF domain
WP7S18E06_03120	COG2203	Gaf domain
WP7S18E06_03130	COG4771	TonB-dependent receptor
WP7S18E06_03160	COG1278	Cold shock
WP7S18E06_03230	COG0697	spore germination
WP7S18E06_03290	COG0840	transmembrane signaling receptor activity
WP7S18E06_03300	COG4772	TonB-dependent receptor
WP7S18E06_03410	COG0629	single-stranded DNA binding
WP7S18E06_03420	COG2197	response regulator
WP7S18E06_03430	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
WP7S18E06_03440	COG3706	GGDEF domain
WP7S18E06_03450	COG3047	cAMP biosynthetic process
WP7S18E06_03460	COG0840	transmembrane signaling receptor activity
WP7S18E06_03510	COG3135	benzoate transporter
WP7S18E06_03520	COG1396	sequence-specific DNA binding
WP7S18E06_03540	COG2926	Belongs to the UPF0265 family
WP7S18E06_03560	COG3028	Belongs to the UPF0307 family
WP7S18E06_03570	COG0312	modulator of DNA gyrase
WP7S18E06_03580	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
WP7S18E06_03590	COG5007	Belongs to the BolA IbaG family
WP7S18E06_03610	COG2854	intermembrane phospholipid transfer
WP7S18E06_03620	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
WP7S18E06_03630	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
WP7S18E06_03640	COG1127	ABC transporter
WP7S18E06_03650	COG0517	IMP dehydrogenase activity
WP7S18E06_03650	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
WP7S18E06_03660	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
WP7S18E06_03670	COG3117	lipopolysaccharide transmembrane transporter activity
WP7S18E06_03680	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
WP7S18E06_03690	COG1137	ATPase activity
WP7S18E06_03700	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
WP7S18E06_03720	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
WP7S18E06_03730	COG1660	Displays ATPase and GTPase activities
WP7S18E06_03740	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
WP7S18E06_03750	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
WP7S18E06_03750	COG3711	transcriptional antiterminator
WP7S18E06_03780	COG3964	amidohydrolase
WP7S18E06_03840	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
WP7S18E06_03850	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
WP7S18E06_03870	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
WP7S18E06_03880	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
WP7S18E06_03890	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
WP7S18E06_03900	COG0723	plastoquinol--plastocyanin reductase activity
WP7S18E06_03910	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
WP7S18E06_03920	COG2857	Cytochrome c1
WP7S18E06_03930	COG0625	glutathione transferase activity
WP7S18E06_03940	COG2969	positive regulation of protein catabolic process
WP7S18E06_03950	COG2823	Periplasmic or secreted lipoprotein
WP7S18E06_03960	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
WP7S18E06_03970	COG0792	nuclease activity
WP7S18E06_03980	COG3107	peptidoglycan biosynthetic process
WP7S18E06_03990	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
WP7S18E06_04000	COG2001	Belongs to the MraZ family
WP7S18E06_04010	COG0275	rRNA processing
WP7S18E06_04020	COG3116	cell division
WP7S18E06_04030	COG0768	penicillin binding
WP7S18E06_04050	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
WP7S18E06_04060	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
WP7S18E06_04070	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
WP7S18E06_04080	COG0772	Belongs to the SEDS family
WP7S18E06_04090	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
WP7S18E06_04100	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
WP7S18E06_04110	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
WP7S18E06_04120	COG0849	cell division
WP7S18E06_04130	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
WP7S18E06_04140	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
WP7S18E06_04160	COG0653	protein targeting
WP7S18E06_04180	COG0494	nUDIX hydrolase
WP7S18E06_04190	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
WP7S18E06_04200	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
WP7S18E06_04230	COG1459	type II secretion system
WP7S18E06_04240	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
WP7S18E06_04280	COG2186	Transcriptional regulator
WP7S18E06_04290	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
WP7S18E06_04300	COG0508	dehydrogenase complex catalyzes the overall conversion of
WP7S18E06_04310	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
WP7S18E06_04330	COG0840	transmembrane signaling receptor activity
WP7S18E06_04340	COG0840	transmembrane signaling receptor activity
WP7S18E06_04350	COG1752	Esterase of the alpha-beta hydrolase superfamily
WP7S18E06_04360	COG1049	propionate catabolic process, 2-methylcitrate cycle
WP7S18E06_04370	COG2200	EAL domain
WP7S18E06_04390	COG1280	lysine exporter protein (LysE YggA)
WP7S18E06_04410	COG0523	cobalamin synthesis protein
WP7S18E06_04420	COG0477	Major facilitator Superfamily
WP7S18E06_04450	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
WP7S18E06_04460	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
WP7S18E06_04510	COG0784	Response regulator, receiver
WP7S18E06_04510	COG0835	chemotaxis
WP7S18E06_04530	COG1444	tRNA N-acetyltransferase activity
WP7S18E06_04590	COG1803	Methylglyoxal synthase
WP7S18E06_04620	COG0252	asparaginase activity
WP7S18E06_04660	COG1263	PTS System
WP7S18E06_04660	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
WP7S18E06_04670	COG0366	Alpha amylase catalytic
WP7S18E06_04680	COG0110	maltose O-acetyltransferase activity
WP7S18E06_04690	COG1522	sequence-specific DNA binding
WP7S18E06_04700	COG5006	permease, DMT superfamily
WP7S18E06_04720	COG1012	belongs to the aldehyde dehydrogenase family
WP7S18E06_04730	COG1177	transmembrane transport
WP7S18E06_04740	COG1176	ABC-type spermidine putrescine transport system, permease component I
WP7S18E06_04750	COG3842	ATPase activity
WP7S18E06_04760	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
WP7S18E06_04770	COG0583	DNA-binding transcription factor activity
WP7S18E06_04780	COG1757	Na H antiporter
WP7S18E06_04810	COG0297	glycogen (starch) synthase activity
WP7S18E06_04820	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
WP7S18E06_04830	COG2813	Specifically methylates the guanine in position
WP7S18E06_04840	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
WP7S18E06_04850	COG5001	Diguanylate cyclase
WP7S18E06_04850	COG3706	GGDEF domain
WP7S18E06_04850	COG2203	Gaf domain
WP7S18E06_04850	COG4251	negative regulation of phosphorylation
WP7S18E06_04870	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
WP7S18E06_04890	COG2995	paraquat-inducible protein a
WP7S18E06_04900	COG3008	intermembrane lipid transfer
WP7S18E06_04900	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
WP7S18E06_04910	COG3009	Protein conserved in bacteria
WP7S18E06_04920	COG2885	chlorophyll binding
WP7S18E06_04920	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
WP7S18E06_04940	COG3240	lipase activity
WP7S18E06_04950	COG3111	PFAM Bacterial OB fold (BOF) protein
WP7S18E06_04970	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
WP7S18E06_04980	COG1194	a g-specific adenine glycosylase
WP7S18E06_05000	COG3409	Peptidoglycan-binding domain 1 protein
WP7S18E06_05000	COG3267	Type II secretory pathway component ExeA
WP7S18E06_05010	COG0617	tRNA 3'-terminal CCA addition
WP7S18E06_05040	COG1346	cytolysis
WP7S18E06_05050	COG1380	Effector of murein hydrolase LrgA
WP7S18E06_05060	COG0583	DNA-binding transcription factor activity
WP7S18E06_05120	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
WP7S18E06_05130	COG0306	phosphate transporter
WP7S18E06_05140	COG1392	Phosphate transport regulator
WP7S18E06_05170	COG1560	Kdo2-lipid A biosynthetic process
WP7S18E06_05180	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
WP7S18E06_05180	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
WP7S18E06_05190	COG1538	Outer membrane efflux protein
WP7S18E06_05200	COG0494	nUDIX hydrolase
WP7S18E06_05210	COG3151	Protein conserved in bacteria
WP7S18E06_05230	COG3150	esterase
WP7S18E06_05240	COG1051	belongs to the nudix hydrolase family
WP7S18E06_05270	COG1566	PFAM secretion protein HlyD family protein
WP7S18E06_05280	COG1289	transmembrane transporter activity
WP7S18E06_05290	COG0187	DNA topoisomerase II activity
WP7S18E06_05320	COG0583	DNA-binding transcription factor activity
WP7S18E06_05400	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
WP7S18E06_05450	COG0204	Acyl-transferase
WP7S18E06_05460	COG1842	Phage shock protein A
WP7S18E06_05490	COG2827	Endonuclease containing a URI domain
WP7S18E06_05510	COG2962	Rard protein
WP7S18E06_05520	COG1573	uracil-dna glycosylase
WP7S18E06_05530	COG0697	spore germination
WP7S18E06_05540	COG0583	DNA-binding transcription factor activity
WP7S18E06_05550	COG1108	ABC-type Mn2 Zn2 transport systems permease components
WP7S18E06_05560	COG1121	(ABC) transporter
WP7S18E06_05570	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
WP7S18E06_05610	COG0739	heme binding
WP7S18E06_05630	COG3068	Protein conserved in bacteria
WP7S18E06_05670	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
WP7S18E06_05680	COG1546	Belongs to the CinA family
WP7S18E06_05690	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
WP7S18E06_05710	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
WP7S18E06_05720	COG0527	aspartate kinase activity
WP7S18E06_05730	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
WP7S18E06_05750	COG1686	Belongs to the peptidase S11 family
WP7S18E06_05760	COG0586	Pfam SNARE associated Golgi protein
WP7S18E06_05770	COG1253	flavin adenine dinucleotide binding
WP7S18E06_05780	COG0525	valine-tRNA ligase activity
WP7S18E06_05790	COG2927	DNA polymerase III (CHI subunit)
WP7S18E06_05800	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
WP7S18E06_05810	COG0795	lipopolysaccharide-transporting ATPase activity
WP7S18E06_05830	COG0795	lipopolysaccharide-transporting ATPase activity
WP7S18E06_06090	COG4695	Portal protein
WP7S18E06_06250	COG2932	Transcriptional regulator
WP7S18E06_06270	COG4974	Belongs to the 'phage' integrase family
WP7S18E06_06280	COG0582	viral genome integration into host DNA
WP7S18E06_06330	COG1196	nuclear chromosome segregation
WP7S18E06_06350	COG0004	ammonium transporteR
WP7S18E06_06360	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
WP7S18E06_06390	COG0084	hydrolase, TatD family'
WP7S18E06_06400	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
WP7S18E06_06420	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
WP7S18E06_06430	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
WP7S18E06_06440	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
WP7S18E06_06450	COG0813	purine-nucleoside phosphorylase activity
WP7S18E06_06460	COG5001	Diguanylate cyclase
WP7S18E06_06460	COG3447	MASE1 domain protein
WP7S18E06_06460	COG5002	protein histidine kinase activity
WP7S18E06_06480	COG0560	Phosphoserine phosphatase
WP7S18E06_06530	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
WP7S18E06_06540	COG0776	regulation of translation
WP7S18E06_06570	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
WP7S18E06_06580	COG0735	belongs to the Fur family
WP7S18E06_06630	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
WP7S18E06_06640	COG0513	Belongs to the DEAD box helicase family
WP7S18E06_06650	COG3022	response to hydroperoxide
WP7S18E06_06680	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
WP7S18E06_06690	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
WP7S18E06_06700	COG0762	integral membrane protein
WP7S18E06_06710	COG1872	DUF167
WP7S18E06_06740	COG4166	transmembrane transport
WP7S18E06_06780	COG1024	Enoyl-CoA hydratase
WP7S18E06_06810	COG4221	oxidoreductase activity
WP7S18E06_06820	COG0442	prolyl-tRNA aminoacylation
WP7S18E06_06830	COG0840	transmembrane signaling receptor activity
WP7S18E06_06840	COG0632	four-way junction helicase activity
WP7S18E06_06850	COG2255	four-way junction helicase activity
WP7S18E06_06860	COG1271	oxidase subunit
WP7S18E06_06870	COG1294	oxidase, subunit
WP7S18E06_06880	COG4890	Cyd operon protein YbgT
WP7S18E06_06890	COG3790	cyd operon protein YbgE
WP7S18E06_06900	COG0824	Thioesterase
WP7S18E06_06910	COG0811	peptide transport
WP7S18E06_06940	COG0823	Involved in the tonB-independent uptake of proteins
WP7S18E06_06950	COG2885	chlorophyll binding
WP7S18E06_06960	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
WP7S18E06_06970	COG0840	transmembrane signaling receptor activity
WP7S18E06_06980	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
WP7S18E06_06990	COG0676	glucose-6-phosphate 1-epimerase activity
WP7S18E06_07000	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
WP7S18E06_07010	COG1640	4-alpha-glucanotransferase
WP7S18E06_07020	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
WP7S18E06_07060	COG1051	belongs to the nudix hydrolase family
WP7S18E06_07070	COG2130	NADP-dependent
WP7S18E06_07080	COG1764	response to oxidative stress
WP7S18E06_07090	COG1846	Transcriptional regulator
WP7S18E06_07160	COG0561	phosphatase activity
WP7S18E06_07190	COG0733	neurotransmitter:sodium symporter activity
WP7S18E06_07210	COG0733	neurotransmitter:sodium symporter activity
WP7S18E06_07260	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
WP7S18E06_07290	COG1794	racemase activity, acting on amino acids and derivatives
WP7S18E06_07320	COG2731	YhcH YjgK YiaL family protein
WP7S18E06_07340	COG0668	transmembrane transport
WP7S18E06_07360	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
WP7S18E06_07430	COG0583	DNA-binding transcription factor activity
WP7S18E06_07440	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
WP7S18E06_07460	COG0488	(ABC) transporter
WP7S18E06_07470	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
WP7S18E06_07470	COG0517	IMP dehydrogenase activity
WP7S18E06_07480	COG1585	Membrane protein implicated in regulation of membrane protease activity
WP7S18E06_07490	COG0330	HflC and HflK could
WP7S18E06_07500	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
WP7S18E06_07500	COG1648	precorrin-2 dehydrogenase activity
WP7S18E06_07510	COG0175	sulfate reduction
WP7S18E06_07520	COG2895	sulfate adenylyltransferase (ATP) activity
WP7S18E06_07530	COG3273	potassium ion transport
WP7S18E06_07530	COG0471	metal ion transport
WP7S18E06_07540	COG0529	Catalyzes the synthesis of activated sulfate
WP7S18E06_07580	COG0840	transmembrane signaling receptor activity
WP7S18E06_07620	COG1136	(ABC) transporter
WP7S18E06_07650	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
WP7S18E06_07680	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
WP7S18E06_07690	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
WP7S18E06_07700	COG0163	prenyltransferase activity
WP7S18E06_07730	COG1131	(ABC) transporter
WP7S18E06_07740	COG0842	Transport permease protein
WP7S18E06_07750	COG1775	2-hydroxyglutaryl-CoA dehydratase, D-component
WP7S18E06_07760	COG1924	4 iron, 4 sulfur cluster binding
WP7S18E06_07800	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
WP7S18E06_07810	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
WP7S18E06_07840	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
WP7S18E06_07850	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
WP7S18E06_07860	COG1489	DNA binding
WP7S18E06_07880	COG1643	Atp-dependent helicase
WP7S18E06_07890	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
WP7S18E06_07900	COG0346	lactoylglutathione lyase activity
WP7S18E06_07920	COG2076	Multidrug Resistance protein
WP7S18E06_07940	COG3437	response regulator, receiver
WP7S18E06_07940	COG0784	Response regulator, receiver
WP7S18E06_07960	COG0671	phosphoesterase, PA-phosphatase related
WP7S18E06_07990	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
WP7S18E06_08000	COG0038	chloride channel
WP7S18E06_08020	COG0316	Belongs to the HesB IscA family
WP7S18E06_08030	COG3335	DDE superfamily endonuclease
WP7S18E06_08050	COG1280	lysine exporter protein (LysE YggA)
WP7S18E06_08060	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
WP7S18E06_08070	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
WP7S18E06_08090	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
WP7S18E06_08150	COG0745	RESPONSE REGULATOR receiver
WP7S18E06_08160	COG3104	oligopeptide transport
WP7S18E06_08170	COG1210	Utp--glucose-1-phosphate uridylyltransferase
WP7S18E06_08180	COG1555	photosystem II stabilization
WP7S18E06_08200	COG2350	Protein conserved in bacteria
WP7S18E06_08210	COG2917	probably involved in intracellular septation
WP7S18E06_08220	COG0076	glutamate decarboxylase activity
WP7S18E06_08230	COG1272	protein, Hemolysin III
WP7S18E06_08240	COG2985	domain, Protein
WP7S18E06_08240	COG0569	domain protein
WP7S18E06_08280	COG0784	Response regulator, receiver
WP7S18E06_08280	COG0835	chemotaxis
WP7S18E06_08290	COG2755	lipolytic protein G-D-S-L family
WP7S18E06_08300	COG4181	ATPase activity
WP7S18E06_08310	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
WP7S18E06_08320	COG1090	epimerase
WP7S18E06_08330	COG2200	EAL domain
WP7S18E06_08340	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
WP7S18E06_08350	COG2234	aminopeptidase activity
WP7S18E06_08350	COG4935	Belongs to the peptidase S8 family
WP7S18E06_08360	COG0220	tRNA (guanine-N7-)-methyltransferase activity
WP7S18E06_08370	COG3171	Protein conserved in bacteria
WP7S18E06_08380	COG2066	Belongs to the glutaminase family
WP7S18E06_08390	COG2897	thiosulfate sulfurtransferase activity
WP7S18E06_08410	COG1132	(ABC) transporter
WP7S18E06_08440	COG0582	viral genome integration into host DNA
WP7S18E06_08490	COG4735	regulation of single-species biofilm formation
WP7S18E06_08500	COG4974	Belongs to the 'phage' integrase family
WP7S18E06_08560	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
WP7S18E06_08590	COG0446	pyridine nucleotide-disulphide oxidoreductase
WP7S18E06_08620	COG1342	Belongs to the UPF0251 family
WP7S18E06_08630	COG0582	viral genome integration into host DNA
WP7S18E06_08660	COG4974	Belongs to the 'phage' integrase family
WP7S18E06_08750	COG0582	viral genome integration into host DNA
WP7S18E06_08760	COG4584	PFAM Integrase catalytic
WP7S18E06_08770	COG1484	DNA-dependent DNA replication
WP7S18E06_08810	COG3385	transposase activity
WP7S18E06_08850	COG4974	Belongs to the 'phage' integrase family
WP7S18E06_08930	COG3335	DDE superfamily endonuclease
WP7S18E06_08940	COG1609	Transcriptional regulator
WP7S18E06_08950	COG2190	(PTS) system
WP7S18E06_08950	COG1263	PTS System
WP7S18E06_08950	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
WP7S18E06_08970	COG3076	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome
WP7S18E06_08980	COG5001	Diguanylate cyclase
WP7S18E06_08980	COG3300	MHYT domain
WP7S18E06_09000	COG2207	Transcriptional regulator
WP7S18E06_09010	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
WP7S18E06_09020	COG3059	membrane
WP7S18E06_09050	COG4628	conserved protein (DUF2132)
WP7S18E06_09060	COG0688	phosphatidylethanolamine metabolic process
WP7S18E06_09070	COG1162	GTPase activity
WP7S18E06_09080	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
WP7S18E06_09090	COG1278	Cold shock
WP7S18E06_09110	COG0840	transmembrane signaling receptor activity
WP7S18E06_09120	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
WP7S18E06_09170	COG0848	biopolymer transport protein
WP7S18E06_09180	COG0811	peptide transport
WP7S18E06_09190	COG0811	peptide transport
WP7S18E06_09220	COG4174	ABC transporter (Permease)
WP7S18E06_09230	COG4239	(ABC) transporter, permease
WP7S18E06_09250	COG0444	Belongs to the ABC transporter superfamily
WP7S18E06_09260	COG4608	Belongs to the ABC transporter superfamily
WP7S18E06_09280	COG2195	Cleaves the N-terminal amino acid of tripeptides
WP7S18E06_09300	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
WP7S18E06_09340	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
WP7S18E06_09390	COG0243	molybdopterin cofactor binding
WP7S18E06_09420	COG1116	anion transmembrane transporter activity
WP7S18E06_09420	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
WP7S18E06_09430	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
WP7S18E06_09440	COG1116	anion transmembrane transporter activity
WP7S18E06_09450	COG2146	nitrite reductase [NAD(P)H] activity
WP7S18E06_09450	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
WP7S18E06_09460	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
WP7S18E06_09460	COG2146	nitrite reductase [NAD(P)H] activity
WP7S18E06_09470	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
WP7S18E06_09480	COG2313	pseudouridylate synthase activity
WP7S18E06_09500	COG1858	cytochrome C peroxidase
WP7S18E06_09570	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
WP7S18E06_09580	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
WP7S18E06_09610	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
WP7S18E06_09700	COG1028	Short-chain dehydrogenase reductase Sdr
WP7S18E06_09710	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
WP7S18E06_09730	COG0521	Mo-molybdopterin cofactor biosynthetic process
WP7S18E06_09760	COG2966	Psort location CytoplasmicMembrane, score
WP7S18E06_09780	COG3610	response to peptide
WP7S18E06_09800	COG4175	Glycine betaine
WP7S18E06_09810	COG4176	ABC-type proline glycine betaine transport system permease component
WP7S18E06_09820	COG2113	Glycine betaine
WP7S18E06_09830	COG0175	sulfate reduction
WP7S18E06_09840	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
WP7S18E06_09850	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
WP7S18E06_09860	COG0384	phenazine biosynthesis protein PhzF
WP7S18E06_09870	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
WP7S18E06_09880	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
WP7S18E06_09900	COG0786	glutamate:sodium symporter activity
WP7S18E06_09910	COG0252	asparaginase activity
WP7S18E06_09920	COG3139	Protein of unknown function (DUF1315)
WP7S18E06_09960	COG0616	signal peptide processing
WP7S18E06_09970	COG1902	pentaerythritol trinitrate reductase activity
WP7S18E06_09970	COG0446	pyridine nucleotide-disulphide oxidoreductase
WP7S18E06_09980	COG0778	Nitroreductase
WP7S18E06_10020	COG2264	protein methyltransferase activity
WP7S18E06_10030	COG0604	alcohol dehydrogenase
WP7S18E06_10040	COG0583	DNA-binding transcription factor activity
WP7S18E06_10050	COG2190	(PTS) system
WP7S18E06_10050	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
WP7S18E06_10050	COG1263	PTS System
WP7S18E06_10060	COG4145	pantothenate transmembrane transporter activity
WP7S18E06_10080	COG0439	Biotin carboxylase
WP7S18E06_10090	COG0511	ligase activity, forming carbon-carbon bonds
WP7S18E06_10100	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
WP7S18E06_10110	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
WP7S18E06_10130	COG5001	Diguanylate cyclase
WP7S18E06_10130	COG3300	MHYT domain
WP7S18E06_10170	COG3381	protein complex oligomerization
WP7S18E06_10200	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
WP7S18E06_10220	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
WP7S18E06_10230	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
WP7S18E06_10230	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
WP7S18E06_10270	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
WP7S18E06_10280	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
WP7S18E06_10290	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
WP7S18E06_10300	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
WP7S18E06_10310	COG4172	Belongs to the ABC transporter superfamily
WP7S18E06_10350	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
WP7S18E06_10360	COG0142	geranyltranstransferase activity
WP7S18E06_10370	COG1722	exodeoxyribonuclease VII activity
WP7S18E06_10380	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
WP7S18E06_10390	COG1360	Flagellar Motor Protein
WP7S18E06_10420	COG1534	Rna-binding protein
WP7S18E06_10430	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
WP7S18E06_10450	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
WP7S18E06_10460	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
WP7S18E06_10470	COG0149	triose-phosphate isomerase activity
WP7S18E06_10480	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
WP7S18E06_10490	COG0779	Required for maturation of 30S ribosomal subunits
WP7S18E06_10500	COG0195	Participates in both transcription termination and antitermination
WP7S18E06_10510	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
WP7S18E06_10520	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
WP7S18E06_10530	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
WP7S18E06_10540	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
WP7S18E06_10550	COG1185	polyribonucleotide nucleotidyltransferase activity
WP7S18E06_10560	COG2211	Major facilitator Superfamily
WP7S18E06_10580	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
WP7S18E06_10600	COG0114	fumarate hydratase activity
WP7S18E06_10620	COG1966	Carbon starvation protein
WP7S18E06_10630	COG3279	Response regulator of the LytR AlgR family
WP7S18E06_10640	COG3275	phosphorelay sensor kinase activity
WP7S18E06_10780	COG0312	modulator of DNA gyrase
WP7S18E06_10790	COG0312	modulator of DNA gyrase
WP7S18E06_10810	COG4974	Belongs to the 'phage' integrase family
WP7S18E06_10820	COG3706	GGDEF domain
WP7S18E06_10830	COG1970	mechanosensitive ion channel activity
WP7S18E06_10850	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
WP7S18E06_10870	COG0789	Transcriptional regulator
WP7S18E06_10900	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
WP7S18E06_10910	COG3545	Serine hydrolase
WP7S18E06_10930	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
WP7S18E06_10950	COG0321	lipoyl(octanoyl) transferase activity
WP7S18E06_10960	COG2921	Belongs to the UPF0250 family
WP7S18E06_10970	COG1686	Belongs to the peptidase S11 family
WP7S18E06_10980	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
WP7S18E06_10990	COG2951	lytic endotransglycosylase activity
WP7S18E06_11000	COG0772	Belongs to the SEDS family
WP7S18E06_11010	COG0772	Belongs to the SEDS family
WP7S18E06_11020	COG0768	penicillin binding
WP7S18E06_11030	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
WP7S18E06_11040	COG0799	negative regulation of ribosome biogenesis
WP7S18E06_11050	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
WP7S18E06_11080	COG0495	leucyl-tRNA aminoacylation
WP7S18E06_11090	COG2888	peptidyl-tyrosine sulfation
WP7S18E06_11100	COG0815	Transfers the fatty acyl group on membrane lipoproteins
WP7S18E06_11110	COG4535	Mg2 and Co2 transporter CorC
WP7S18E06_11120	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
WP7S18E06_11130	COG1702	phosphate starvation-inducible protein PhoH
WP7S18E06_11140	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
WP7S18E06_11150	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
WP7S18E06_11160	COG1335	isochorismatase
WP7S18E06_11180	COG3706	GGDEF domain
WP7S18E06_11210	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
WP7S18E06_11230	COG3706	GGDEF domain
WP7S18E06_11250	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
WP7S18E06_11270	COG3647	Membrane
WP7S18E06_11280	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
WP7S18E06_11300	COG0516	GMP reductase activity
WP7S18E06_11320	COG0642	Histidine kinase
WP7S18E06_11330	COG0745	RESPONSE REGULATOR receiver
WP7S18E06_11400	COG3214	Protein conserved in bacteria
WP7S18E06_11460	COG3029	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
WP7S18E06_11470	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
WP7S18E06_11480	COG1053	succinate dehydrogenase
WP7S18E06_11500	COG0584	glycerophosphoryl diester phosphodiesterase
WP7S18E06_11510	COG3264	Mechanosensitive ion channel
WP7S18E06_11510	COG1511	domain protein
WP7S18E06_11530	COG0739	heme binding
WP7S18E06_11570	COG0583	DNA-binding transcription factor activity
WP7S18E06_11610	COG0583	DNA-binding transcription factor activity
WP7S18E06_11620	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
WP7S18E06_11680	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
WP7S18E06_11690	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
WP7S18E06_11710	COG0338	D12 class N6 adenine-specific DNA methyltransferase
WP7S18E06_11730	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
WP7S18E06_11750	COG0180	Tryptophanyl-tRNA synthetase
WP7S18E06_11780	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
WP7S18E06_11800	COG1012	belongs to the aldehyde dehydrogenase family
WP7S18E06_11820	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
WP7S18E06_11840	COG0674	pyruvate-flavodoxin oxidoreductase activity
WP7S18E06_11840	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
WP7S18E06_11840	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
WP7S18E06_11840	COG1013	pyruvate-flavodoxin oxidoreductase activity
WP7S18E06_11860	COG0488	(ABC) transporter
WP7S18E06_11880	COG0366	Alpha amylase catalytic
WP7S18E06_11940	COG0490	domain, Protein
WP7S18E06_11940	COG0471	metal ion transport
WP7S18E06_11950	COG0012	GTP binding
WP7S18E06_11960	COG0193	aminoacyl-tRNA hydrolase activity
WP7S18E06_11970	COG0737	Belongs to the 5'-nucleotidase family
WP7S18E06_11980	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
WP7S18E06_11990	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
WP7S18E06_12000	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
WP7S18E06_12010	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
WP7S18E06_12020	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
WP7S18E06_12030	COG2890	protein-(glutamine-N5) methyltransferase activity
WP7S18E06_12050	COG2912	Transglutaminase-like superfamily
WP7S18E06_12060	COG2877	3-deoxy-8-phosphooctulonate synthase activity
WP7S18E06_12070	COG1301	dicarboxylic acid transport
WP7S18E06_12090	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
WP7S18E06_12120	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
WP7S18E06_12130	COG1115	amino acid carrier protein
WP7S18E06_12160	COG0714	Associated with various cellular activities
WP7S18E06_12210	COG3104	oligopeptide transport
WP7S18E06_12220	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
WP7S18E06_12230	COG1678	Uncharacterized ACR, COG1678
WP7S18E06_12250	COG0189	ligase activity
WP7S18E06_12260	COG1385	rRNA (uridine-N3-)-methyltransferase activity
WP7S18E06_12280	COG3091	SprT-like family
WP7S18E06_12300	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
WP7S18E06_12320	COG3385	transposase activity
WP7S18E06_12340	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
WP7S18E06_12350	COG0739	heme binding
WP7S18E06_12360	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
WP7S18E06_12370	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
WP7S18E06_12370	COG3408	Glycogen debranching enzyme
WP7S18E06_12390	COG1881	PFAM PEBP family protein
WP7S18E06_12410	COG0583	DNA-binding transcription factor activity
WP7S18E06_12430	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
WP7S18E06_12450	COG0583	DNA-binding transcription factor activity
WP7S18E06_12460	COG1028	Short-chain dehydrogenase reductase Sdr
WP7S18E06_12470	COG0616	signal peptide processing
WP7S18E06_12480	COG3724	N-succinylarginine dihydrolase activity
WP7S18E06_12520	COG0840	transmembrane signaling receptor activity
WP7S18E06_12540	COG2971	BadF BadG BcrA BcrD
WP7S18E06_12560	COG4608	Belongs to the ABC transporter superfamily
WP7S18E06_12570	COG0444	Belongs to the ABC transporter superfamily
WP7S18E06_12580	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
WP7S18E06_12590	COG0601	transmembrane transport
WP7S18E06_12600	COG4166	transmembrane transport
WP7S18E06_12610	COG0784	Response regulator, receiver
WP7S18E06_12610	COG2205	protein histidine kinase activity
WP7S18E06_12650	COG3220	belongs to the UPF0276 family
WP7S18E06_12710	COG1289	transmembrane transporter activity
WP7S18E06_12720	COG0303	'Molybdopterin
WP7S18E06_12730	COG0746	molybdenum cofactor guanylyltransferase activity
WP7S18E06_12750	COG4662	Binding-protein-dependent transport system inner membrane component
WP7S18E06_12780	COG3852	Histidine kinase
WP7S18E06_12790	COG1910	domain protein
WP7S18E06_12800	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
WP7S18E06_12870	COG3383	formate dehydrogenase (NAD+) activity
WP7S18E06_12870	COG3383	formate dehydrogenase (NAD+) activity
WP7S18E06_12880	COG0437	4 iron, 4 sulfur cluster binding
WP7S18E06_12910	COG0281	malic enzyme
WP7S18E06_12950	COG2706	6-phosphogluconolactonase activity
WP7S18E06_12970	COG1196	nuclear chromosome segregation
WP7S18E06_12970	COG3264	Mechanosensitive ion channel
WP7S18E06_12980	COG0469	pyruvate kinase activity
WP7S18E06_13010	COG4651	solute:proton antiporter activity
WP7S18E06_13010	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
WP7S18E06_13030	COG2974	May be involved in recombination
WP7S18E06_13050	COG0420	3'-5' exonuclease activity
WP7S18E06_13080	COG3038	cytochrome b561
WP7S18E06_13110	COG2190	(PTS) system
WP7S18E06_13130	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
WP7S18E06_13140	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
WP7S18E06_13150	COG0542	response to heat
WP7S18E06_13180	COG1720	tRNA m6t6A37 methyltransferase activity
WP7S18E06_13220	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
WP7S18E06_13230	COG4988	ABC transporter
WP7S18E06_13240	COG0745	RESPONSE REGULATOR receiver
WP7S18E06_13260	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
WP7S18E06_13290	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
WP7S18E06_13300	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
WP7S18E06_13320	COG0083	homoserine kinase activity
WP7S18E06_13330	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
WP7S18E06_13350	COG0488	(ABC) transporter
WP7S18E06_13360	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
WP7S18E06_13390	COG0813	purine-nucleoside phosphorylase activity
WP7S18E06_13420	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
WP7S18E06_13420	COG2205	protein histidine kinase activity
WP7S18E06_13430	COG3384	dioxygenase
WP7S18E06_13450	COG1283	sodium-dependent phosphate transmembrane transporter activity
WP7S18E06_13470	COG0531	amino acid
WP7S18E06_13490	COG0531	amino acid
WP7S18E06_13530	COG1917	Cupin 2, conserved barrel domain protein
WP7S18E06_13530	COG1396	sequence-specific DNA binding
WP7S18E06_13540	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
WP7S18E06_13580	COG3152	Membrane
WP7S18E06_13630	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
WP7S18E06_13640	COG2375	cellular response to nickel ion
WP7S18E06_13660	COG0577	efflux transmembrane transporter activity
WP7S18E06_13660	COG1136	(ABC) transporter
WP7S18E06_13670	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
WP7S18E06_13700	COG1227	inorganic diphosphatase activity
WP7S18E06_13710	COG0497	DNA recombination
WP7S18E06_13720	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
WP7S18E06_13730	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
WP7S18E06_13740	COG0443	Heat shock 70 kDa protein
WP7S18E06_13750	COG0484	heat shock protein binding
WP7S18E06_13810	COG1285	pathogenesis
WP7S18E06_13840	COG0640	Transcriptional regulator
WP7S18E06_13900	COG0095	Lipoate-protein ligase
WP7S18E06_13940	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
WP7S18E06_13950	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
WP7S18E06_13990	COG0708	Exodeoxyribonuclease III
WP7S18E06_14020	COG2211	Major facilitator Superfamily
WP7S18E06_14110	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
WP7S18E06_14130	COG3335	DDE superfamily endonuclease
WP7S18E06_14140	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
WP7S18E06_14150	COG1845	cytochrome c oxidase, subunit III
WP7S18E06_14160	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
WP7S18E06_14170	COG0109	protoheme IX farnesyltransferase activity
WP7S18E06_14180	COG2814	Major facilitator Superfamily
WP7S18E06_14230	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
WP7S18E06_14270	COG1988	membrane-bound metal-dependent
WP7S18E06_14280	COG0159	tryptophan synthase activity
WP7S18E06_14290	COG0133	tryptophan synthase activity
WP7S18E06_14300	COG0134	indole-3-glycerol-phosphate synthase activity
WP7S18E06_14300	COG0135	phosphoribosylanthranilate isomerase activity
WP7S18E06_14310	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
WP7S18E06_14320	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
WP7S18E06_14320	COG0512	Glutamine amidotransferase of anthranilate synthase
WP7S18E06_14330	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
WP7S18E06_14350	COG0009	L-threonylcarbamoyladenylate synthase
WP7S18E06_14370	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
WP7S18E06_14390	COG1946	Acyl-CoA thioesterase
WP7S18E06_14430	COG1309	transcriptional regulator
WP7S18E06_14440	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
WP7S18E06_14450	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
WP7S18E06_14480	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
WP7S18E06_14490	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
WP7S18E06_14490	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
WP7S18E06_14500	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
WP7S18E06_14560	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
WP7S18E06_14580	COG1091	dTDP-4-dehydrorhamnose reductase activity
WP7S18E06_14600	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
WP7S18E06_14620	COG3132	Protein of unknown function, DUF480
WP7S18E06_14710	COG1278	Cold shock
WP7S18E06_14760	COG4166	transmembrane transport
WP7S18E06_14770	COG0697	spore germination
WP7S18E06_14780	COG1349	DNA-binding transcription factor activity
WP7S18E06_14790	COG1882	Formate acetyltransferase
WP7S18E06_14800	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
WP7S18E06_14810	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
WP7S18E06_14870	COG0622	Phosphoesterase
WP7S18E06_14900	COG1261	Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly
WP7S18E06_14910	COG0835	chemotaxis
WP7S18E06_14910	COG0784	Response regulator, receiver
WP7S18E06_14920	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
WP7S18E06_14930	COG1815	bacterial-type flagellum-dependent cell motility
WP7S18E06_14970	COG4787	bacterial-type flagellum-dependent cell motility
WP7S18E06_14990	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
WP7S18E06_15000	COG1706	bacterial-type flagellum-dependent cell motility
WP7S18E06_15010	COG3951	Flagellar rod assembly protein muramidase FlgJ
WP7S18E06_15010	COG1705	Flagellar rod assembly protein muramidase FlgJ
WP7S18E06_15020	COG1256	bacterial-type flagellum assembly
WP7S18E06_15040	COG2239	Acts as a magnesium transporter
WP7S18E06_15060	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
WP7S18E06_15070	COG2716	regulation of RNA biosynthetic process
WP7S18E06_15100	COG3852	Histidine kinase
WP7S18E06_15120	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
WP7S18E06_15130	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
WP7S18E06_15140	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
WP7S18E06_15150	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
WP7S18E06_15190	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
WP7S18E06_15210	COG0590	tRNA wobble adenosine to inosine editing
WP7S18E06_15220	COG0573	inorganic phosphate transmembrane transporter activity
WP7S18E06_15230	COG0581	inorganic phosphate transmembrane transporter activity
WP7S18E06_15250	COG0704	Plays a role in the regulation of phosphate uptake
WP7S18E06_15260	COG1253	flavin adenine dinucleotide binding
WP7S18E06_15290	COG0531	amino acid
WP7S18E06_15330	COG1126	abc transporter atp-binding protein
WP7S18E06_15340	COG0765	amino acid transport
WP7S18E06_15350	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
WP7S18E06_15360	COG3706	GGDEF domain
WP7S18E06_15370	COG2271	Major facilitator Superfamily
WP7S18E06_15400	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
WP7S18E06_15460	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
WP7S18E06_15470	COG0477	Major facilitator Superfamily
WP7S18E06_15480	COG0123	including yeast histone deacetylase and acetoin utilization protein
WP7S18E06_15500	COG1199	ATP-dependent helicase activity
WP7S18E06_15530	COG1448	Aminotransferase
WP7S18E06_15540	COG0433	COG0433 Predicted ATPase
WP7S18E06_15570	COG2333	competence protein COMEC
WP7S18E06_15570	COG0658	competence protein
WP7S18E06_15590	COG1663	tetraacyldisaccharide 4'-kinase activity
WP7S18E06_15600	COG2835	tetraacyldisaccharide 4'-kinase activity
WP7S18E06_15610	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
WP7S18E06_15620	COG2197	response regulator
WP7S18E06_15630	COG0322	excinuclease ABC activity
WP7S18E06_15720	COG3301	Polysulphide reductase, NrfD
WP7S18E06_15730	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
WP7S18E06_15750	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
WP7S18E06_15790	COG2203	Gaf domain
WP7S18E06_15790	COG2199	diguanylate cyclase activity
WP7S18E06_15850	COG2119	membrane
WP7S18E06_15860	COG0023	Translation Initiation Factor
WP7S18E06_15910	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
WP7S18E06_15940	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
WP7S18E06_15940	COG2205	protein histidine kinase activity
WP7S18E06_15960	COG4138	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system
WP7S18E06_15980	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
WP7S18E06_15990	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
WP7S18E06_16000	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
WP7S18E06_16010	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
WP7S18E06_16020	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
WP7S18E06_16040	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
WP7S18E06_16050	COG0505	Belongs to the CarA family
WP7S18E06_16060	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
WP7S18E06_16070	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
WP7S18E06_16130	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
WP7S18E06_16140	COG0513	Belongs to the DEAD box helicase family
WP7S18E06_16160	COG4104	PAAR repeat-containing protein
WP7S18E06_16190	COG0789	Transcriptional regulator
WP7S18E06_16220	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
WP7S18E06_16230	COG0765	amino acid transport
WP7S18E06_16250	COG0493	'glutamate synthase
WP7S18E06_16260	COG0069	glutamate synthase activity
WP7S18E06_16260	COG0070	glutamate synthase
WP7S18E06_16260	COG0067	glutamate synthase
WP7S18E06_16270	COG1242	4 iron, 4 sulfur cluster binding
WP7S18E06_16380	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
WP7S18E06_16390	COG0574	Belongs to the PEP-utilizing enzyme family
WP7S18E06_16390	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
WP7S18E06_16470	COG1464	Belongs to the NlpA lipoprotein family
WP7S18E06_16480	COG0671	phosphoesterase, PA-phosphatase related
WP7S18E06_16490	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
WP7S18E06_16500	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
WP7S18E06_16520	COG0101	tRNA pseudouridine synthase activity
WP7S18E06_16530	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
WP7S18E06_16540	COG0285	dihydrofolate synthase activity
WP7S18E06_16550	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
WP7S18E06_16560	COG2920	part of a sulfur-relay system
WP7S18E06_16570	COG1289	transmembrane transporter activity
WP7S18E06_16580	COG0670	Belongs to the BI1 family
WP7S18E06_16610	COG2194	sulfuric ester hydrolase activity
WP7S18E06_16620	COG0392	lysyltransferase activity
WP7S18E06_16620	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
WP7S18E06_16640	COG0840	transmembrane signaling receptor activity
WP7S18E06_16650	COG5001	Diguanylate cyclase
WP7S18E06_16660	COG0564	pseudouridine synthase activity
WP7S18E06_16690	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
WP7S18E06_16710	COG0625	glutathione transferase activity
WP7S18E06_16720	COG0625	glutathione transferase activity
WP7S18E06_16740	COG0367	asparagine synthase
WP7S18E06_16760	COG4651	solute:proton antiporter activity
WP7S18E06_16760	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
WP7S18E06_16770	COG0647	UMP catabolic process
WP7S18E06_16790	COG1902	pentaerythritol trinitrate reductase activity
WP7S18E06_16800	COG1253	flavin adenine dinucleotide binding
WP7S18E06_16820	COG0247	lactate metabolic process
WP7S18E06_16820	COG0277	FAD linked oxidase domain protein
WP7S18E06_16840	COG2050	protein possibly involved in aromatic compounds catabolism
WP7S18E06_16860	COG2056	Na+-H+ antiporter family
WP7S18E06_16870	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
WP7S18E06_16900	COG0346	lactoylglutathione lyase activity
WP7S18E06_16910	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
WP7S18E06_16920	COG4660	Part of a membrane complex involved in electron transport
WP7S18E06_16930	COG4659	FMN binding
WP7S18E06_16940	COG4658	electron transport chain
WP7S18E06_16960	COG2878	Part of a membrane complex involved in electron transport
WP7S18E06_16970	COG4657	Part of a membrane complex involved in electron transport
WP7S18E06_16980	COG0697	spore germination
WP7S18E06_17000	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
WP7S18E06_17010	COG1288	antiporter activity
WP7S18E06_17020	COG0436	Aminotransferase
WP7S18E06_17040	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
WP7S18E06_17050	COG2027	D-alanyl-D-alanine carboxypeptidase
WP7S18E06_17060	COG1061	Type III restriction enzyme res subunit
WP7S18E06_17070	COG1566	PFAM secretion protein HlyD family protein
WP7S18E06_17090	COG1966	Carbon starvation protein
WP7S18E06_17100	COG3279	Response regulator of the LytR AlgR family
WP7S18E06_17110	COG3275	phosphorelay sensor kinase activity
WP7S18E06_17120	COG2199	diguanylate cyclase activity
WP7S18E06_17120	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
WP7S18E06_17130	COG1454	alcohol dehydrogenase
WP7S18E06_17130	COG1012	belongs to the aldehyde dehydrogenase family
WP7S18E06_17150	COG2095	MarC family integral membrane protein
WP7S18E06_17170	COG0601	transmembrane transport
WP7S18E06_17180	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
WP7S18E06_17210	COG0861	Integral membrane protein TerC family
WP7S18E06_17220	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
WP7S18E06_17240	COG1301	dicarboxylic acid transport
WP7S18E06_17260	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
WP7S18E06_17290	COG0537	adenosine 5'-monophosphoramidase activity
WP7S18E06_17360	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
WP7S18E06_17370	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
WP7S18E06_17390	COG2354	Protein conserved in bacteria
WP7S18E06_17420	COG2233	PERMEase
WP7S18E06_17430	COG3150	esterase
WP7S18E06_17440	COG1252	NADH dehydrogenase
WP7S18E06_17490	COG0393	Putative heavy-metal-binding
WP7S18E06_17510	COG1648	precorrin-2 dehydrogenase activity
WP7S18E06_17510	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
WP7S18E06_17550	COG4667	esterase of the alpha-beta hydrolase superfamily
WP7S18E06_17560	COG1619	proteins homologs of microcin C7 resistance protein MccF
WP7S18E06_17570	COG1368	sulfuric ester hydrolase activity
WP7S18E06_17600	COG0527	aspartate kinase activity
WP7S18E06_17610	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
WP7S18E06_17610	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
WP7S18E06_17620	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
WP7S18E06_17660	COG0596	Alpha beta hydrolase
WP7S18E06_17670	COG0346	lactoylglutathione lyase activity
WP7S18E06_17690	COG0583	DNA-binding transcription factor activity
WP7S18E06_17700	COG1620	l-lactate permease
WP7S18E06_17710	COG0247	lactate metabolic process
WP7S18E06_17720	COG1139	Iron-sulfur cluster binding protein
WP7S18E06_17790	COG1136	(ABC) transporter
WP7S18E06_17810	COG2814	Major facilitator Superfamily
WP7S18E06_17850	COG0672	)-iron permease
WP7S18E06_17890	COG0659	secondary active sulfate transmembrane transporter activity
WP7S18E06_18030	COG4584	PFAM Integrase catalytic
WP7S18E06_18040	COG1484	DNA-dependent DNA replication
WP7S18E06_18060	COG1309	transcriptional regulator
WP7S18E06_18090	COG1136	(ABC) transporter
WP7S18E06_18120	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
WP7S18E06_18160	COG2916	Histone family protein nucleoid-structuring protein H-NS
WP7S18E06_18170	COG4584	PFAM Integrase catalytic
WP7S18E06_18180	COG1484	DNA-dependent DNA replication
WP7S18E06_18220	COG3385	transposase activity
WP7S18E06_18230	COG2194	sulfuric ester hydrolase activity
WP7S18E06_18240	COG2194	sulfuric ester hydrolase activity
WP7S18E06_18250	COG3039	Transposase
WP7S18E06_18280	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
WP7S18E06_18350	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
WP7S18E06_18360	COG0840	transmembrane signaling receptor activity
WP7S18E06_18380	COG2201	protein-glutamate methylesterase activity
WP7S18E06_18400	COG0835	chemotaxis
WP7S18E06_18410	COG3290	protein histidine kinase activity
WP7S18E06_18410	COG0840	transmembrane signaling receptor activity
WP7S18E06_18420	COG0643	Histidine kinase
WP7S18E06_18420	COG2198	Histidine kinase
WP7S18E06_18450	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
WP7S18E06_18460	COG0437	4 iron, 4 sulfur cluster binding
WP7S18E06_18470	COG5557	Pfam Polysulphide reductase, NrfD
WP7S18E06_18480	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
WP7S18E06_18490	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
WP7S18E06_18500	COG1773	rubredoxin
WP7S18E06_18510	COG0747	negative chemotaxis
WP7S18E06_18530	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
WP7S18E06_18550	COG3842	ATPase activity
WP7S18E06_18570	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
WP7S18E06_18590	COG0375	protein maturation
WP7S18E06_18600	COG0309	Hydrogenase expression formation protein (HypE)
WP7S18E06_18620	COG0298	carbon dioxide binding
WP7S18E06_18630	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
WP7S18E06_18650	COG1921	L-seryl-tRNASec selenium transferase activity
WP7S18E06_18660	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
WP7S18E06_18680	COG3260	NADH ubiquinone oxidoreductase 20
WP7S18E06_18690	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
WP7S18E06_18700	COG3261	NADH dehydrogenase
WP7S18E06_18700	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
WP7S18E06_18710	COG0650	Formate hydrogenlyase subunit 4
WP7S18E06_18720	COG0651	ATP synthesis coupled electron transport
WP7S18E06_18730	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
WP7S18E06_18740	COG3158	transport of potassium into the cell
WP7S18E06_18760	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
WP7S18E06_18810	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
WP7S18E06_18820	COG0326	Molecular chaperone. Has ATPase activity
WP7S18E06_18830	COG0563	adenylate kinase activity
WP7S18E06_18840	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
WP7S18E06_18860	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
WP7S18E06_18890	COG5001	Diguanylate cyclase
WP7S18E06_18890	COG3300	MHYT domain
WP7S18E06_18900	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
WP7S18E06_18940	COG1021	2,3-dihydroxybenzoate-AMP ligase
WP7S18E06_18950	COG3433	isochorismatase activity
WP7S18E06_18950	COG1535	isochorismatase
WP7S18E06_18960	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
WP7S18E06_18970	COG1028	Short-chain dehydrogenase reductase Sdr
WP7S18E06_18990	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
WP7S18E06_19000	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
WP7S18E06_19020	COG1120	ATPase activity
WP7S18E06_19030	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
WP7S18E06_19040	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
WP7S18E06_19050	COG4771	TonB-dependent receptor
WP7S18E06_19130	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
WP7S18E06_19140	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
WP7S18E06_19150	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
WP7S18E06_19180	COG1570	exodeoxyribonuclease VII activity
WP7S18E06_19190	COG0697	spore germination
WP7S18E06_19230	COG3158	transport of potassium into the cell
WP7S18E06_19260	COG0517	IMP dehydrogenase activity
WP7S18E06_19260	COG0516	GMP reductase activity
WP7S18E06_19270	COG0518	GMP synthase (glutamine-hydrolyzing) activity
WP7S18E06_19270	COG0519	Catalyzes the synthesis of GMP from XMP
WP7S18E06_19340	COG2062	phosphohistidine phosphatase, SixA
WP7S18E06_19360	COG0697	spore germination
WP7S18E06_19370	COG4166	transmembrane transport
WP7S18E06_19380	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
WP7S18E06_19390	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
WP7S18E06_19410	COG4591	ABC-type transport system involved in lipoprotein release permease component
WP7S18E06_19420	COG1136	(ABC) transporter
WP7S18E06_19430	COG4591	ABC-type transport system involved in lipoprotein release permease component
WP7S18E06_19440	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
WP7S18E06_19460	COG0544	peptidyl-prolyl cis-trans isomerase activity
WP7S18E06_19470	COG0740	serine-type endopeptidase activity
WP7S18E06_19480	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
WP7S18E06_19490	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
WP7S18E06_19500	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
WP7S18E06_19510	COG0488	(ABC) transporter
WP7S18E06_19520	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
WP7S18E06_19530	COG3162	membrane
WP7S18E06_19560	COG1024	Enoyl-CoA hydratase
WP7S18E06_19570	COG1115	amino acid carrier protein
WP7S18E06_19590	COG3228	Belongs to the MtfA family
WP7S18E06_19600	COG1584	GPR1 FUN34 yaaH family protein
WP7S18E06_19670	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
WP7S18E06_19680	COG1960	acyl-CoA dehydrogenase activity
WP7S18E06_19700	COG1960	acyl-CoA dehydrogenase activity
WP7S18E06_19710	COG1024	Enoyl-CoA hydratase
WP7S18E06_19720	COG1024	Enoyl-CoA hydratase
WP7S18E06_19740	COG1028	Short-chain dehydrogenase reductase Sdr
WP7S18E06_19760	COG0730	response to heat
WP7S18E06_19790	COG5001	Diguanylate cyclase
WP7S18E06_19790	COG3300	MHYT domain
WP7S18E06_19800	COG0583	DNA-binding transcription factor activity
WP7S18E06_19810	COG2723	6-phospho-beta-galactosidase activity
WP7S18E06_19820	COG3300	MHYT domain
WP7S18E06_19820	COG5001	Diguanylate cyclase
WP7S18E06_19840	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
WP7S18E06_19860	COG0583	DNA-binding transcription factor activity
WP7S18E06_19870	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
WP7S18E06_19880	COG0673	inositol 2-dehydrogenase activity
WP7S18E06_19890	COG0583	DNA-binding transcription factor activity
WP7S18E06_19910	COG1560	Kdo2-lipid A biosynthetic process
WP7S18E06_19920	COG1560	Kdo2-lipid A biosynthetic process
WP7S18E06_19970	COG0417	DNA replication proofreading
WP7S18E06_19980	COG0534	Mate efflux family protein
WP7S18E06_20000	COG0307	riboflavin synthase, alpha
WP7S18E06_20020	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
WP7S18E06_20030	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
WP7S18E06_20040	COG0697	spore germination
WP7S18E06_20050	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
WP7S18E06_20130	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
WP7S18E06_20140	COG3099	Belongs to the UPF0263 family
WP7S18E06_20150	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
WP7S18E06_20160	COG2894	cell division
WP7S18E06_20170	COG0850	regulation of cytokinetic process
WP7S18E06_20180	COG3100	YcgL domain-containing protein
WP7S18E06_20190	COG2951	lytic endotransglycosylase activity
WP7S18E06_20200	COG1760	l-serine dehydratase
WP7S18E06_20210	COG1760	l-serine dehydratase
WP7S18E06_20220	COG3123	guanosine phosphorylase activity
WP7S18E06_20230	COG3335	DDE superfamily endonuclease
WP7S18E06_20280	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
WP7S18E06_20290	COG2067	long-chain fatty acid transport protein
WP7S18E06_20320	COG1595	DNA-templated transcription, initiation
WP7S18E06_20380	COG0714	Associated with various cellular activities
WP7S18E06_20390	COG0183	Belongs to the thiolase family
WP7S18E06_20400	COG1024	Enoyl-CoA hydratase
WP7S18E06_20400	COG1250	3-hydroxyacyl-CoA dehydrogenase
WP7S18E06_20450	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
WP7S18E06_20460	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
WP7S18E06_20470	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
WP7S18E06_20490	COG0549	Belongs to the carbamate kinase family
WP7S18E06_20500	COG0697	spore germination
WP7S18E06_20510	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
WP7S18E06_20510	COG3608	succinylglutamate desuccinylase aspartoacylase
WP7S18E06_20520	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
WP7S18E06_20540	COG0493	'glutamate synthase
WP7S18E06_20540	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
WP7S18E06_20550	COG0402	S-adenosylhomocysteine deaminase activity
WP7S18E06_20560	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
WP7S18E06_20570	COG1529	Aldehyde oxidase and xanthine dehydrogenase
WP7S18E06_20570	COG2080	2 iron, 2 sulfur cluster binding
WP7S18E06_20580	COG2233	PERMEase
WP7S18E06_20590	COG0402	S-adenosylhomocysteine deaminase activity
WP7S18E06_20600	COG2252	PERMEase
WP7S18E06_20610	COG1529	Aldehyde oxidase and xanthine dehydrogenase
WP7S18E06_20620	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
WP7S18E06_20630	COG2080	2 iron, 2 sulfur cluster binding
WP7S18E06_20650	COG3134	Outer membrane lipoprotein
WP7S18E06_20670	COG1288	antiporter activity
WP7S18E06_20680	COG0318	PFAM AMP-dependent synthetase and ligase
WP7S18E06_20690	COG0140	phosphoribosyl-ATP diphosphatase activity
WP7S18E06_20690	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
WP7S18E06_20700	COG0107	imidazoleglycerol-phosphate synthase activity
WP7S18E06_20710	COG2205	protein histidine kinase activity
WP7S18E06_20710	COG2198	Histidine kinase
WP7S18E06_20710	COG0784	Response regulator, receiver
WP7S18E06_20730	COG3437	response regulator, receiver
WP7S18E06_20740	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
WP7S18E06_20750	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
WP7S18E06_20760	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
WP7S18E06_20760	COG0131	Imidazoleglycerol-phosphate dehydratase
WP7S18E06_20770	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
WP7S18E06_20780	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
WP7S18E06_20790	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
WP7S18E06_20810	COG1199	ATP-dependent helicase activity
WP7S18E06_20820	COG1214	PFAM Peptidase M22, glycoprotease
WP7S18E06_20840	COG0596	Alpha beta hydrolase
WP7S18E06_20840	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
WP7S18E06_20840	COG2226	methyltransferase
WP7S18E06_20850	COG0318	PFAM AMP-dependent synthetase and ligase
WP7S18E06_20860	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
WP7S18E06_20890	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
WP7S18E06_20900	COG2832	Protein of unknown function (DUF454)
WP7S18E06_20910	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
WP7S18E06_20930	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
WP7S18E06_20960	COG0517	IMP dehydrogenase activity
WP7S18E06_20960	COG0617	tRNA 3'-terminal CCA addition
WP7S18E06_20960	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
WP7S18E06_20970	COG1643	Atp-dependent helicase
WP7S18E06_20990	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
WP7S18E06_21010	COG3437	response regulator, receiver
WP7S18E06_21020	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
WP7S18E06_21030	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
WP7S18E06_21040	COG0709	Synthesizes selenophosphate from selenide and ATP
WP7S18E06_21070	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
WP7S18E06_21090	COG1254	Belongs to the acylphosphatase family
WP7S18E06_21100	COG0625	glutathione transferase activity
WP7S18E06_21110	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
WP7S18E06_21110	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
WP7S18E06_21120	COG0489	protein tyrosine kinase activity
WP7S18E06_21130	COG0572	uridine kinase
WP7S18E06_21140	COG0717	Belongs to the dCTP deaminase family
WP7S18E06_21150	COG0306	phosphate transporter
WP7S18E06_21160	COG1530	ribonuclease E activity
WP7S18E06_21170	COG0564	pseudouridine synthase activity
WP7S18E06_21180	COG0546	phosphoglycolate phosphatase activity
WP7S18E06_21190	COG0424	maF-like protein
WP7S18E06_21200	COG2814	Major facilitator Superfamily
WP7S18E06_21240	COG1399	metal-binding, possibly nucleic acid-binding protein
WP7S18E06_21250	COG0333	Belongs to the bacterial ribosomal protein bL32 family
WP7S18E06_21260	COG0416	fatty acid biosynthetic process
WP7S18E06_21270	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
WP7S18E06_21290	COG1028	Short-chain dehydrogenase reductase Sdr
WP7S18E06_21300	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
WP7S18E06_21320	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
WP7S18E06_21330	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
WP7S18E06_21340	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
WP7S18E06_21350	COG0470	DNA polymerase III
WP7S18E06_21360	COG0084	hydrolase, TatD family'
WP7S18E06_21390	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
WP7S18E06_21390	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
WP7S18E06_21400	COG3008	intermembrane lipid transfer
WP7S18E06_21410	COG2995	paraquat-inducible protein a
WP7S18E06_21430	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
WP7S18E06_21440	COG0372	Belongs to the citrate synthase family
WP7S18E06_21530	COG4221	oxidoreductase activity
WP7S18E06_21550	COG3141	response to X-ray
WP7S18E06_21670	COG1067	ATP-dependent peptidase activity
WP7S18E06_21680	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
WP7S18E06_21700	COG0488	(ABC) transporter
WP7S18E06_21720	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
WP7S18E06_21720	COG0116	Belongs to the methyltransferase superfamily
WP7S18E06_21740	COG0167	dihydroorotate dehydrogenase activity
WP7S18E06_21750	COG2902	Dehydrogenase
WP7S18E06_21770	COG0308	aminopeptidase N
WP7S18E06_21790	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
WP7S18E06_21800	COG1956	GAF domain-containing protein
WP7S18E06_21820	COG3278	Belongs to the heme-copper respiratory oxidase family
WP7S18E06_21850	COG2010	Cytochrome c
WP7S18E06_21900	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
WP7S18E06_21910	COG0589	response to stress
WP7S18E06_21920	COG0037	tRNA processing
WP7S18E06_21950	COG0625	glutathione transferase activity
WP7S18E06_21960	COG1869	D-ribose catabolic process
WP7S18E06_21970	COG1129	ABC transporter
WP7S18E06_21980	COG1172	Belongs to the binding-protein-dependent transport system permease family
WP7S18E06_21990	COG1879	ABC-type sugar transport system periplasmic component
WP7S18E06_22000	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
WP7S18E06_22010	COG1609	Transcriptional regulator
WP7S18E06_22020	COG5001	Diguanylate cyclase
WP7S18E06_22020	COG3300	MHYT domain
WP7S18E06_22080	COG0776	regulation of translation
WP7S18E06_22090	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
WP7S18E06_22090	COG0072	phenylalanine-tRNA ligase activity
WP7S18E06_22100	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
WP7S18E06_22110	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
WP7S18E06_22120	COG0291	Belongs to the bacterial ribosomal protein bL35 family
WP7S18E06_22130	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
WP7S18E06_22140	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
WP7S18E06_22190	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
WP7S18E06_22210	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
WP7S18E06_22220	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
WP7S18E06_22230	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
WP7S18E06_22240	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
WP7S18E06_22250	COG3313	Fe-S protein
WP7S18E06_22260	COG2942	2-epimerase
WP7S18E06_22270	COG3716	PTS system mannose fructose sorbose family IID component
WP7S18E06_22280	COG3715	PTS system
WP7S18E06_22290	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
WP7S18E06_22290	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
WP7S18E06_22320	COG1609	Transcriptional regulator
WP7S18E06_22330	COG2140	Oxalate decarboxylase
WP7S18E06_22340	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
WP7S18E06_22340	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
WP7S18E06_22340	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
WP7S18E06_22350	COG1105	Belongs to the carbohydrate kinase PfkB family
WP7S18E06_22360	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
WP7S18E06_22360	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
WP7S18E06_22370	COG1609	Transcriptional regulator
WP7S18E06_22380	COG0814	amino acid
WP7S18E06_22400	COG5654	RES domain protein
WP7S18E06_22410	COG0513	Belongs to the DEAD box helicase family
WP7S18E06_22430	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
WP7S18E06_22440	COG2890	protein-(glutamine-N5) methyltransferase activity
WP7S18E06_22450	COG2840	Smr protein MutS2
WP7S18E06_22470	COG3706	GGDEF domain
WP7S18E06_22480	COG0406	alpha-ribazole phosphatase activity
WP7S18E06_22530	COG2824	Alkylphosphonate utilization operon protein PhnA
WP7S18E06_22560	COG0384	phenazine biosynthesis protein PhzF
WP7S18E06_22620	COG0242	peptide deformylase activity
WP7S18E06_22660	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
WP7S18E06_22670	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
WP7S18E06_22690	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
WP7S18E06_22700	COG1434	Gram-negative-bacterium-type cell wall biogenesis
WP7S18E06_22720	COG0205	6-phosphofructokinase activity
WP7S18E06_22730	COG1473	amidohydrolase
WP7S18E06_22740	COG1011	Hydrolase
WP7S18E06_22750	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
WP7S18E06_22780	COG3593	DNA synthesis involved in DNA repair
WP7S18E06_22810	COG0583	DNA-binding transcription factor activity
WP7S18E06_22820	COG0730	response to heat
WP7S18E06_22850	COG1181	Belongs to the D-alanine--D-alanine ligase family
WP7S18E06_22870	COG0386	Belongs to the glutathione peroxidase family
WP7S18E06_22880	COG0513	Belongs to the DEAD box helicase family
WP7S18E06_22890	COG0456	acetyltransferase
WP7S18E06_22910	COG1742	UPF0060 membrane protein
WP7S18E06_22970	COG2329	Antibiotic biosynthesis monooxygenase
WP7S18E06_22980	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
WP7S18E06_23020	COG3243	poly(R)-hydroxyalkanoic acid synthase
WP7S18E06_23040	COG2501	S4 domain
WP7S18E06_23060	COG1132	(ABC) transporter
WP7S18E06_23070	COG1132	(ABC) transporter
WP7S18E06_23090	COG3118	belongs to the thioredoxin family
WP7S18E06_23100	COG0471	metal ion transport
WP7S18E06_23110	COG0058	SHG alpha-glucan phosphorylase activity
WP7S18E06_23170	COG0814	amino acid
WP7S18E06_23180	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
WP7S18E06_23190	COG0514	ATP-dependent DNA helicase (RecQ)
WP7S18E06_23200	COG2766	serine protein kinase
WP7S18E06_23220	COG2719	SpoVR family
WP7S18E06_23230	COG2186	Transcriptional regulator
WP7S18E06_23240	COG3067	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
WP7S18E06_23250	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
WP7S18E06_23260	COG0586	Pfam SNARE associated Golgi protein
WP7S18E06_23280	COG0556	nucleotide-excision repair
WP7S18E06_23290	COG2985	domain, Protein
WP7S18E06_23290	COG0569	domain protein
WP7S18E06_23310	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
WP7S18E06_23350	COG4565	transcriptional regulatory protein
WP7S18E06_23360	COG3290	protein histidine kinase activity
WP7S18E06_23370	COG1846	Transcriptional regulator
WP7S18E06_23370	COG1940	carbohydrate kinase activity
WP7S18E06_23380	COG0840	transmembrane signaling receptor activity
WP7S18E06_23390	COG3012	SEC-C Motif Domain Protein
WP7S18E06_23400	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
WP7S18E06_23410	COG3075	Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses fumarate or nitrate as electron acceptor
WP7S18E06_23420	COG0247	lactate metabolic process
WP7S18E06_23460	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
WP7S18E06_23470	COG0437	4 iron, 4 sulfur cluster binding
WP7S18E06_23480	COG3301	Polysulphide reductase, NrfD
WP7S18E06_23490	COG1138	Cytochrome C-type biogenesis protein
WP7S18E06_23500	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
WP7S18E06_23510	COG3088	subunit of a heme lyase
WP7S18E06_23510	COG4235	cytochrome complex assembly
WP7S18E06_23520	COG1051	belongs to the nudix hydrolase family
WP7S18E06_23540	COG3033	Beta-eliminating lyase
WP7S18E06_23550	COG3033	Beta-eliminating lyase
WP7S18E06_23560	COG3046	protein related to deoxyribodipyrimidine photolyase
WP7S18E06_23570	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
WP7S18E06_23620	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
WP7S18E06_23650	COG4774	siderophore transport
WP7S18E06_23660	COG4977	sequence-specific DNA binding
WP7S18E06_23680	COG0583	DNA-binding transcription factor activity
WP7S18E06_23690	COG2910	NAD(P)H-binding
WP7S18E06_23720	COG0612	Peptidase, M16
WP7S18E06_23730	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
WP7S18E06_23750	COG1944	ATP diphosphatase activity
WP7S18E06_23760	COG2116	formate transmembrane transporter activity
WP7S18E06_23770	COG1882	Formate acetyltransferase
WP7S18E06_23780	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
WP7S18E06_23800	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
WP7S18E06_23820	COG1840	ABC-type Fe3 transport system, periplasmic component
WP7S18E06_23830	COG3842	ATPase activity
WP7S18E06_23850	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
WP7S18E06_23860	COG2983	Belongs to the UPF0260 family
WP7S18E06_23880	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
WP7S18E06_23890	COG0045	succinate-CoA ligase (ADP-forming) activity
WP7S18E06_23900	COG0508	dehydrogenase complex catalyzes the overall conversion of
WP7S18E06_23910	COG0567	Dehydrogenase, E1 component
WP7S18E06_23930	COG1053	succinate dehydrogenase
WP7S18E06_23940	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
WP7S18E06_23990	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
WP7S18E06_24000	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
WP7S18E06_24000	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
WP7S18E06_24020	COG3069	C4-dicarboxylate transmembrane transporter activity
WP7S18E06_24050	COG1451	nucleotide metabolic process
WP7S18E06_24080	COG0254	rRNA binding
WP7S18E06_24090	COG0257	Belongs to the bacterial ribosomal protein bL36 family
WP7S18E06_24110	COG0583	DNA-binding transcription factor activity
WP7S18E06_24130	COG1172	Belongs to the binding-protein-dependent transport system permease family
WP7S18E06_24150	COG1879	ABC-type sugar transport system periplasmic component
WP7S18E06_24160	COG1069	ribulokinase activity
WP7S18E06_24180	COG2160	L-arabinose isomerase activity
WP7S18E06_24190	COG2925	Exonuclease
WP7S18E06_24210	COG3345	alpha-galactosidase
WP7S18E06_24220	COG1380	Effector of murein hydrolase LrgA
WP7S18E06_24230	COG1346	cytolysis
WP7S18E06_24240	COG0295	cytidine deaminase activity
WP7S18E06_24250	COG1022	Amp-dependent synthetase and ligase
WP7S18E06_24280	COG0861	Integral membrane protein TerC family
WP7S18E06_24290	COG2885	chlorophyll binding
WP7S18E06_24300	COG2199	diguanylate cyclase activity
WP7S18E06_24330	COG2154	pterin-4-alpha-carbinolamine dehydratase
WP7S18E06_24340	COG2154	pterin-4-alpha-carbinolamine dehydratase
WP7S18E06_24360	COG3768	UPF0283 membrane protein
WP7S18E06_24370	COG3106	COG3106 Predicted ATPase
WP7S18E06_24400	COG1842	Phage shock protein A
WP7S18E06_24410	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
WP7S18E06_24430	COG4168	peptide transport system, permease
WP7S18E06_24440	COG4171	peptide transport system, permease
WP7S18E06_24470	COG4172	Belongs to the ABC transporter superfamily
WP7S18E06_24490	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
WP7S18E06_24500	COG1286	toxin biosynthetic process
WP7S18E06_24510	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
WP7S18E06_24530	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
WP7S18E06_24540	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
WP7S18E06_24550	COG0531	amino acid
WP7S18E06_24550	COG1674	ftsk spoiiie
WP7S18E06_24570	COG0492	ferredoxin-NADP+ reductase activity
WP7S18E06_24580	COG3706	GGDEF domain
WP7S18E06_24590	COG3134	Outer membrane lipoprotein
WP7S18E06_24600	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
WP7S18E06_24610	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
WP7S18E06_24620	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
WP7S18E06_24630	COG0542	response to heat
WP7S18E06_24640	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
WP7S18E06_24650	COG1278	Cold shock
WP7S18E06_24660	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
WP7S18E06_24710	COG2226	methyltransferase
WP7S18E06_24730	COG0210	DNA helicase
WP7S18E06_24740	COG1205	dead DEAH box helicase
WP7S18E06_24740	COG1111	helicase
WP7S18E06_24760	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
WP7S18E06_24790	COG3039	Transposase
WP7S18E06_24970	COG4584	PFAM Integrase catalytic
WP7S18E06_24980	COG1484	DNA-dependent DNA replication
WP7S18E06_25010	COG3550	peptidyl-serine autophosphorylation
WP7S18E06_25050	COG3501	Rhs element vgr protein
WP7S18E06_25260	COG3501	Rhs element vgr protein
WP7S18E06_25300	COG1435	thymidine kinase activity
WP7S18E06_25310	COG1757	Na H antiporter
WP7S18E06_25320	COG2916	Histone family protein nucleoid-structuring protein H-NS
WP7S18E06_25330	COG2096	Adenosyltransferase
WP7S18E06_25340	COG3530	Putative quorum-sensing-regulated virulence factor
WP7S18E06_25350	COG0602	queuosine metabolic process
WP7S18E06_25360	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
WP7S18E06_25400	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
WP7S18E06_25420	COG0776	regulation of translation
WP7S18E06_25430	COG0539	negative regulation of cytoplasmic translation
WP7S18E06_25440	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
WP7S18E06_25460	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
WP7S18E06_25480	COG0583	DNA-binding transcription factor activity
WP7S18E06_25520	COG0778	Nitroreductase
WP7S18E06_25530	COG5001	Diguanylate cyclase
WP7S18E06_25530	COG3300	MHYT domain
WP7S18E06_25550	COG0583	DNA-binding transcription factor activity
WP7S18E06_25560	COG3437	response regulator, receiver
WP7S18E06_25610	COG4989	oxidoreductase activity
WP7S18E06_25620	COG0724	RNA recognition motif
WP7S18E06_25660	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
WP7S18E06_25680	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
WP7S18E06_25690	COG1360	Flagellar Motor Protein
WP7S18E06_25700	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
WP7S18E06_25710	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
WP7S18E06_25720	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
WP7S18E06_25720	COG0649	NAD binding
WP7S18E06_25750	COG1034	ATP synthesis coupled electron transport
WP7S18E06_25760	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
WP7S18E06_25770	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
WP7S18E06_25780	COG0839	Belongs to the complex I subunit 6 family
WP7S18E06_25790	COG0713	ATP synthesis coupled electron transport
WP7S18E06_25810	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
WP7S18E06_25820	COG1007	ATP synthesis coupled electron transport
WP7S18E06_25830	COG0047	phosphoribosylformylglycinamidine synthase activity
WP7S18E06_25830	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
WP7S18E06_25840	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
WP7S18E06_25850	COG1645	bacterial-type flagellum-dependent swarming motility
WP7S18E06_25860	COG1160	GTP binding
WP7S18E06_25870	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
WP7S18E06_25880	COG2976	Protein conserved in bacteria
WP7S18E06_25890	COG0124	histidyl-tRNA synthetase
WP7S18E06_25930	COG0820	rRNA (adenine-C2-)-methyltransferase activity
WP7S18E06_25940	COG0105	UTP biosynthetic process
WP7S18E06_25950	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
WP7S18E06_25970	COG0633	Ferredoxin
WP7S18E06_25980	COG0443	Heat shock 70 kDa protein
WP7S18E06_25990	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
WP7S18E06_26010	COG0822	iron-sulfur transferase activity
WP7S18E06_26020	COG1104	cysteine desulfurase activity
WP7S18E06_26060	COG3154	lipid carrier protein
WP7S18E06_26070	COG0826	peptidase U32
WP7S18E06_26080	COG0826	peptidase U32
WP7S18E06_26110	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
WP7S18E06_26120	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
WP7S18E06_26130	COG1862	Preprotein translocase
WP7S18E06_26140	COG0343	queuine tRNA-ribosyltransferase activity
WP7S18E06_26150	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
WP7S18E06_26160	COG0517	IMP dehydrogenase activity
WP7S18E06_26180	COG3634	alkyl hydroperoxide reductase activity
WP7S18E06_26220	COG1393	Belongs to the ArsC family
WP7S18E06_26230	COG0798	PFAM Bile acid sodium symporter
WP7S18E06_26290	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
WP7S18E06_26290	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
WP7S18E06_26300	COG0509	glycine decarboxylation via glycine cleavage system
WP7S18E06_26310	COG0404	The glycine cleavage system catalyzes the degradation of glycine
WP7S18E06_26320	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
WP7S18E06_26330	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
WP7S18E06_26360	COG2814	Major facilitator Superfamily
WP7S18E06_26370	COG0625	glutathione transferase activity
WP7S18E06_26390	COG0483	inositol monophosphate 1-phosphatase activity
WP7S18E06_26430	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
WP7S18E06_26470	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
WP7S18E06_26490	COG2089	acid synthase
WP7S18E06_26500	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
WP7S18E06_26540	COG1083	cytidylyl-transferase
WP7S18E06_26590	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
WP7S18E06_26630	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
WP7S18E06_26630	COG0301	tRNA thio-modification
WP7S18E06_26650	COG4953	penicillin-binding protein 1C
WP7S18E06_26660	COG2373	Large extracellular alpha-helical protein
WP7S18E06_26670	COG0446	pyridine nucleotide-disulphide oxidoreductase
WP7S18E06_26690	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
WP7S18E06_26730	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
WP7S18E06_26750	COG2431	L-lysine efflux transmembrane transporter activity
WP7S18E06_26760	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
WP7S18E06_26770	COG3124	Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP
WP7S18E06_26800	COG1393	Belongs to the ArsC family
WP7S18E06_26820	COG4783	chaperone-mediated protein folding
WP7S18E06_26830	COG0425	Belongs to the sulfur carrier protein TusA family
WP7S18E06_26880	COG3842	ATPase activity
WP7S18E06_26890	COG3833	ABC-type maltose transport systems, permease component
WP7S18E06_26900	COG1175	transmembrane transport
WP7S18E06_26920	COG3081	Nucleoid-associated protein
WP7S18E06_26930	COG3082	Protein of unknown function (DUF1414)
WP7S18E06_26940	COG3083	sulfuric ester hydrolase activity
WP7S18E06_26950	COG4771	TonB-dependent receptor
WP7S18E06_26960	COG1770	oligopeptidase
WP7S18E06_27000	COG4574	serine-type endopeptidase inhibitor activity
WP7S18E06_27010	COG3085	chromosome segregation
WP7S18E06_27020	COG0583	DNA-binding transcription factor activity
WP7S18E06_27030	COG0287	Prephenate dehydrogenase
WP7S18E06_27030	COG1605	Chorismate mutase
WP7S18E06_27040	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
WP7S18E06_27050	COG0584	glycerophosphoryl diester phosphodiesterase
WP7S18E06_27070	COG1349	DNA-binding transcription factor activity
WP7S18E06_27080	COG2271	Major facilitator Superfamily
WP7S18E06_27090	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
WP7S18E06_27100	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
WP7S18E06_27110	COG0583	DNA-binding transcription factor activity
WP7S18E06_27150	COG0656	L-ascorbic acid biosynthetic process
WP7S18E06_27160	COG2814	Major facilitator Superfamily
WP7S18E06_27180	COG1294	oxidase, subunit
WP7S18E06_27190	COG1271	oxidase subunit
WP7S18E06_27200	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
WP7S18E06_27220	COG2979	Protein of unknown function (DUF533)
WP7S18E06_27270	COG2271	Major facilitator Superfamily
WP7S18E06_27280	COG0583	DNA-binding transcription factor activity
WP7S18E06_27300	COG2807	transmembrane transport
WP7S18E06_27320	COG1187	pseudouridine synthase activity
WP7S18E06_27360	COG0346	lactoylglutathione lyase activity
WP7S18E06_27380	COG1403	HNH endonuclease
WP7S18E06_27400	COG2964	Protein conserved in bacteria
WP7S18E06_27410	COG3681	Belongs to the UPF0597 family
WP7S18E06_27430	COG0814	amino acid
WP7S18E06_27470	COG1166	arginine decarboxylase activity
WP7S18E06_27480	COG2195	Cleaves the N-terminal amino acid of tripeptides
WP7S18E06_27540	COG0583	DNA-binding transcription factor activity
WP7S18E06_27560	COG2759	Belongs to the formate--tetrahydrofolate ligase family
WP7S18E06_27570	COG2759	Belongs to the formate--tetrahydrofolate ligase family
WP7S18E06_27580	COG0840	transmembrane signaling receptor activity
WP7S18E06_27590	COG0302	gtp cyclohydrolase
WP7S18E06_27610	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
WP7S18E06_27620	COG2267	carboxylic ester hydrolase activity
WP7S18E06_27630	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
WP7S18E06_27660	COG0314	molybdopterin synthase activity
WP7S18E06_27670	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
WP7S18E06_27680	COG0315	cyclic pyranopterin monophosphate synthase activity
WP7S18E06_27690	COG0521	Mo-molybdopterin cofactor biosynthetic process
WP7S18E06_27700	COG3005	denitrification pathway
WP7S18E06_27720	COG0348	domain, Protein
WP7S18E06_27730	COG0437	4 iron, 4 sulfur cluster binding
WP7S18E06_27740	COG0243	molybdopterin cofactor binding
WP7S18E06_27760	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
WP7S18E06_27760	COG1149	4fe-4S ferredoxin, iron-sulfur binding domain protein
WP7S18E06_27770	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
WP7S18E06_27780	COG3850	Histidine kinase
WP7S18E06_27790	COG2197	response regulator
WP7S18E06_27850	COG0121	glutamine amidotransferase
WP7S18E06_27860	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
WP7S18E06_27870	COG1960	acyl-CoA dehydrogenase activity
WP7S18E06_27890	COG3437	response regulator, receiver
WP7S18E06_27890	COG0784	Response regulator, receiver
WP7S18E06_27920	COG0328	RNA-DNA hybrid ribonuclease activity
WP7S18E06_27930	COG2226	methyltransferase
WP7S18E06_27940	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
WP7S18E06_27950	COG1388	LysM domain
WP7S18E06_27950	COG0741	lytic transglycosylase activity
WP7S18E06_27960	COG3021	interspecies interaction between organisms
WP7S18E06_27980	COG1607	acyl-coa hydrolase
WP7S18E06_28010	COG0741	lytic transglycosylase activity
WP7S18E06_28030	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
WP7S18E06_28050	COG2911	Protein conserved in bacteria
WP7S18E06_28060	COG0729	surface antigen
WP7S18E06_28080	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
WP7S18E06_28090	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
WP7S18E06_28110	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
WP7S18E06_28130	COG4134	Bacterial extracellular solute-binding protein
WP7S18E06_28150	COG4136	ATPase activity
WP7S18E06_28160	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
WP7S18E06_28170	COG2951	lytic endotransglycosylase activity
WP7S18E06_28200	COG1846	Transcriptional regulator
WP7S18E06_28220	COG0033	Phosphoglucomutase
WP7S18E06_28230	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
WP7S18E06_28240	COG0596	Alpha beta hydrolase
WP7S18E06_28270	COG0716	FMN binding
WP7S18E06_28290	COG0735	belongs to the Fur family
WP7S18E06_28300	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
WP7S18E06_28320	COG2190	(PTS) system
WP7S18E06_28320	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
WP7S18E06_28320	COG1263	PTS System
WP7S18E06_28330	COG0363	glucosamine-6-phosphate deaminase activity
WP7S18E06_28340	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
WP7S18E06_28350	COG1940	carbohydrate kinase activity
WP7S18E06_28350	COG1846	Transcriptional regulator
WP7S18E06_28360	COG2194	sulfuric ester hydrolase activity
WP7S18E06_28370	COG0217	transcriptional regulatory protein
WP7S18E06_28380	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
WP7S18E06_28390	COG1801	Protein of unknown function DUF72
WP7S18E06_28400	COG4106	trans-aconitate 2-methyltransferase activity
WP7S18E06_28410	COG0500	methyltransferase
WP7S18E06_28450	COG0450	alkyl hydroperoxide reductase
WP7S18E06_28460	COG0583	DNA-binding transcription factor activity
WP7S18E06_28490	COG0791	NLP P60 protein
WP7S18E06_28520	COG1309	transcriptional regulator
WP7S18E06_28600	COG0534	Mate efflux family protein
WP7S18E06_28640	COG3385	transposase activity
WP7S18E06_28650	COG0674	pyruvate-flavodoxin oxidoreductase activity
WP7S18E06_28650	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
WP7S18E06_28650	COG1013	pyruvate-flavodoxin oxidoreductase activity
WP7S18E06_28650	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
WP7S18E06_28670	COG3217	Mosc domain protein beta barrel domain protein
WP7S18E06_28670	COG0633	Ferredoxin
WP7S18E06_28670	COG0633	Ferredoxin
WP7S18E06_28670	COG3217	Mosc domain protein beta barrel domain protein
WP7S18E06_28690	COG0501	Belongs to the peptidase M48B family
WP7S18E06_28700	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
WP7S18E06_28710	COG2226	methyltransferase
WP7S18E06_28710	COG1073	alpha beta
WP7S18E06_28720	COG0156	8-amino-7-oxononanoate synthase activity
WP7S18E06_28730	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
WP7S18E06_28770	COG0017	Asparaginyl-tRNA synthetase
WP7S18E06_28780	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
WP7S18E06_28810	COG3069	C4-dicarboxylate transmembrane transporter activity
WP7S18E06_28830	COG0583	DNA-binding transcription factor activity
WP7S18E06_28840	COG1393	Belongs to the ArsC family
WP7S18E06_28850	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
WP7S18E06_28860	COG1876	peptidase activity
WP7S18E06_28880	COG3263	regulation of cellular component size
WP7S18E06_28920	COG1280	lysine exporter protein (LysE YggA)
WP7S18E06_28980	COG0564	pseudouridine synthase activity
WP7S18E06_29000	COG1454	alcohol dehydrogenase
WP7S18E06_29010	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
WP7S18E06_29020	COG0702	epimerase
WP7S18E06_29030	COG2914	Belongs to the UPF0125 (RnfH) family
WP7S18E06_29040	COG2867	negative regulation of translational initiation
WP7S18E06_29050	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
WP7S18E06_29060	COG0582	viral genome integration into host DNA
WP7S18E06_29080	COG2916	Histone family protein nucleoid-structuring protein H-NS
WP7S18E06_29200	COG0514	ATP-dependent DNA helicase (RecQ)
WP7S18E06_29210	COG1940	carbohydrate kinase activity
WP7S18E06_29220	COG0583	DNA-binding transcription factor activity
WP7S18E06_29230	COG3048	D-serine ammonia-lyase activity
WP7S18E06_29250	COG0538	isocitrate dehydrogenase activity
WP7S18E06_29260	COG2207	Transcriptional regulator
WP7S18E06_29270	COG1482	cell wall glycoprotein biosynthetic process
WP7S18E06_29300	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
WP7S18E06_29320	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
WP7S18E06_29330	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
WP7S18E06_29330	COG1263	PTS System
WP7S18E06_29340	COG1609	Transcriptional regulator
WP7S18E06_29360	COG0789	Transcriptional regulator
WP7S18E06_29420	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
WP7S18E06_29420	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
WP7S18E06_29420	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
WP7S18E06_29440	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
WP7S18E06_29460	COG1187	pseudouridine synthase activity
WP7S18E06_29480	COG0482	sulfurtransferase activity
WP7S18E06_29490	COG2915	High frequency lysogenization protein hflD homolog
WP7S18E06_29500	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
WP7S18E06_29510	COG2850	peptidyl-arginine hydroxylation
WP7S18E06_29530	COG3153	acetyltransferase
WP7S18E06_29550	COG0625	glutathione transferase activity
WP7S18E06_29560	COG0259	pyridoxamine-phosphate oxidase activity
WP7S18E06_29610	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
WP7S18E06_29610	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
WP7S18E06_29620	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
WP7S18E06_29650	COG4235	cytochrome complex assembly
WP7S18E06_29650	COG3088	subunit of a heme lyase
WP7S18E06_29660	COG4235	cytochrome complex assembly
WP7S18E06_29660	COG3088	subunit of a heme lyase
WP7S18E06_29670	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
WP7S18E06_29680	COG1138	Cytochrome C-type biogenesis protein
WP7S18E06_29690	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
WP7S18E06_29700	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
WP7S18E06_29710	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
WP7S18E06_29720	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
WP7S18E06_29750	COG0835	chemotaxis
WP7S18E06_29770	COG1192	Involved in chromosome partitioning
WP7S18E06_29780	COG1360	Flagellar Motor Protein
WP7S18E06_29790	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
WP7S18E06_29800	COG2201	protein-glutamate methylesterase activity
WP7S18E06_29810	COG0643	Histidine kinase
WP7S18E06_29810	COG2198	Histidine kinase
WP7S18E06_29810	COG0784	Response regulator, receiver
WP7S18E06_29820	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
WP7S18E06_29870	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
WP7S18E06_29890	COG1684	flagellar biosynthetic protein fliR
WP7S18E06_30000	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
WP7S18E06_30020	COG1677	Flagellar hook-basal body complex protein FliE
WP7S18E06_30050	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
WP7S18E06_30070	COG3064	Membrane
WP7S18E06_30070	COG1073	alpha beta
WP7S18E06_30070	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
WP7S18E06_30080	COG2994	toxin metabolic process
WP7S18E06_30100	COG2274	protein secretion by the type I secretion system
WP7S18E06_30120	COG2274	protein secretion by the type I secretion system
WP7S18E06_30130	COG0745	RESPONSE REGULATOR receiver
WP7S18E06_30160	COG1737	Transcriptional regulator
WP7S18E06_30170	COG0469	pyruvate kinase activity
WP7S18E06_30190	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
WP7S18E06_30200	COG1960	acyl-CoA dehydrogenase activity
WP7S18E06_30220	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
WP7S18E06_30230	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
WP7S18E06_30270	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
WP7S18E06_30290	COG1401	restriction endodeoxyribonuclease activity
WP7S18E06_30300	COG0732	type I restriction modification DNA specificity domain
WP7S18E06_30310	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
WP7S18E06_30420	COG2003	Belongs to the UPF0758 family
WP7S18E06_30580	COG3311	Transcriptional regulator
WP7S18E06_30680	COG0243	molybdopterin cofactor binding
WP7S18E06_30690	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
WP7S18E06_30700	COG0583	DNA-binding transcription factor activity
WP7S18E06_30770	COG1012	belongs to the aldehyde dehydrogenase family
WP7S18E06_30770	COG1454	alcohol dehydrogenase
WP7S18E06_30790	COG1454	alcohol dehydrogenase
WP7S18E06_30790	COG1012	belongs to the aldehyde dehydrogenase family
WP7S18E06_30800	COG1882	Formate acetyltransferase
WP7S18E06_30810	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
WP7S18E06_30830	COG4869	propanediol catabolic process
WP7S18E06_30870	COG5002	protein histidine kinase activity
WP7S18E06_30880	COG0745	RESPONSE REGULATOR receiver
WP7S18E06_30890	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
WP7S18E06_30900	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
WP7S18E06_30910	COG1388	LysM domain
WP7S18E06_30910	COG1376	ErfK ybiS ycfS ynhG family protein
WP7S18E06_30940	COG3129	Specifically methylates the adenine in position 1618 of 23S rRNA
WP7S18E06_30950	COG0791	NLP P60 protein
WP7S18E06_30960	COG2091	lysine biosynthetic process via aminoadipic acid
WP7S18E06_30970	COG3118	belongs to the thioredoxin family
WP7S18E06_30980	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
WP7S18E06_30990	COG0788	formyltetrahydrofolate deformylase activity
WP7S18E06_31010	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
WP7S18E06_31050	COG0366	Alpha amylase catalytic
WP7S18E06_31060	COG0739	heme binding
WP7S18E06_31060	COG0741	lytic transglycosylase activity
WP7S18E06_31060	COG1196	nuclear chromosome segregation
WP7S18E06_31070	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
WP7S18E06_31080	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
WP7S18E06_31090	COG0673	inositol 2-dehydrogenase activity
WP7S18E06_31130	COG3152	Membrane
WP7S18E06_31170	COG1032	radical SAM domain protein
WP7S18E06_31190	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
WP7S18E06_31200	COG1566	PFAM secretion protein HlyD family protein
WP7S18E06_31210	COG2199	diguanylate cyclase activity
WP7S18E06_31210	COG2203	Gaf domain
WP7S18E06_31220	COG1752	Esterase of the alpha-beta hydrolase superfamily
WP7S18E06_31230	COG0733	neurotransmitter:sodium symporter activity
WP7S18E06_31290	COG0281	malic enzyme
WP7S18E06_31310	COG0534	Mate efflux family protein
WP7S18E06_31340	COG2233	PERMEase
WP7S18E06_31350	COG0095	Lipoate-protein ligase
WP7S18E06_31360	COG1115	amino acid carrier protein
WP7S18E06_31370	COG0019	diaminopimelate decarboxylase activity
WP7S18E06_31390	COG0678	peroxiredoxin activity
WP7S18E06_31410	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
WP7S18E06_31450	COG1131	(ABC) transporter
WP7S18E06_31460	COG0545	Peptidyl-prolyl cis-trans isomerase
WP7S18E06_31470	COG3142	Participates in the control of copper homeostasis
WP7S18E06_31520	COG5002	protein histidine kinase activity
WP7S18E06_31530	COG0745	RESPONSE REGULATOR receiver
WP7S18E06_31540	COG0346	lactoylglutathione lyase activity
WP7S18E06_31550	COG1804	L-carnitine dehydratase bile acid-inducible protein F
WP7S18E06_31560	COG1960	acyl-CoA dehydrogenase activity
WP7S18E06_31570	COG3284	Transcriptional regulator
WP7S18E06_31580	COG1012	belongs to the aldehyde dehydrogenase family
WP7S18E06_31600	COG0697	spore germination
WP7S18E06_31610	COG4565	transcriptional regulatory protein
WP7S18E06_31620	COG3290	protein histidine kinase activity
WP7S18E06_31630	COG0281	malic enzyme
WP7S18E06_31650	COG1846	Transcriptional regulator
WP7S18E06_31660	COG1566	PFAM secretion protein HlyD family protein
WP7S18E06_31750	COG0602	queuosine metabolic process
WP7S18E06_31760	COG1328	CTP reductase activity
WP7S18E06_31780	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
WP7S18E06_31790	COG3115	cell septum assembly
WP7S18E06_31800	COG1196	nuclear chromosome segregation
WP7S18E06_31820	COG2860	membrane
WP7S18E06_31840	COG3108	Peptidase M15
WP7S18E06_31850	COG2989	Protein conserved in bacteria
WP7S18E06_31880	COG0463	Glycosyl transferase, family 2
WP7S18E06_31910	COG0366	Alpha amylase catalytic
WP7S18E06_31980	COG3706	GGDEF domain
WP7S18E06_31990	COG0037	tRNA processing
WP7S18E06_32000	COG3590	peptidase
WP7S18E06_32020	COG0488	(ABC) transporter
WP7S18E06_32040	COG0531	amino acid
WP7S18E06_32060	COG1073	alpha beta
WP7S18E06_32070	COG1073	alpha beta
WP7S18E06_32090	COG1234	tRNA 3'-trailer cleavage
WP7S18E06_32100	COG0814	amino acid
WP7S18E06_32130	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
WP7S18E06_32140	COG1982	Orn Lys Arg decarboxylase major
WP7S18E06_32150	COG0531	amino acid
WP7S18E06_32160	COG3710	Transcriptional regulator
WP7S18E06_32170	COG0825	malonyl-CoA metabolic process
WP7S18E06_32190	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
WP7S18E06_32200	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
WP7S18E06_32210	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
WP7S18E06_32220	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
WP7S18E06_32230	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
WP7S18E06_32260	COG0750	zinc metalloprotease
WP7S18E06_32270	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
WP7S18E06_32280	COG0575	Belongs to the CDS family
WP7S18E06_32290	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
WP7S18E06_32300	COG0233	cytoplasmic translational termination
WP7S18E06_32310	COG0528	UMP kinase activity
WP7S18E06_32320	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
WP7S18E06_32330	COG0052	Belongs to the universal ribosomal protein uS2 family
WP7S18E06_32340	COG0024	Methionine aminopeptidase
WP7S18E06_32350	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
WP7S18E06_32360	COG2171	N-acyltransferase activity
WP7S18E06_32380	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
WP7S18E06_32380	COG1263	PTS System
WP7S18E06_32400	COG4580	involved in the transport of maltose and maltodextrins
WP7S18E06_32420	COG0564	pseudouridine synthase activity
WP7S18E06_32430	COG3098	single-species biofilm formation
WP7S18E06_32480	COG5595	Zn-ribbon-containing, possibly nucleic-acid-binding protein (DUF2310)
WP7S18E06_32500	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
WP7S18E06_32500	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
WP7S18E06_32520	COG3706	GGDEF domain
WP7S18E06_32530	COG1611	Belongs to the LOG family
WP7S18E06_32540	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
WP7S18E06_32550	COG0473	3-isopropylmalate dehydrogenase activity
WP7S18E06_32570	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
WP7S18E06_32580	COG2363	Small membrane protein
WP7S18E06_32600	COG0583	DNA-binding transcription factor activity
WP7S18E06_32610	COG0840	transmembrane signaling receptor activity
WP7S18E06_32620	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
WP7S18E06_32650	COG1477	protein flavinylation
WP7S18E06_32660	COG2871	sodium ion transport
WP7S18E06_32670	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
WP7S18E06_32680	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
WP7S18E06_32690	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
WP7S18E06_32700	COG1805	sodium ion transport
WP7S18E06_32710	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
WP7S18E06_32720	COG0271	Belongs to the BolA IbaG family
WP7S18E06_32730	COG2813	Specifically methylates the guanine in position
WP7S18E06_32750	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
WP7S18E06_32770	COG2211	Major facilitator Superfamily
WP7S18E06_32780	COG3248	Nucleoside-binding outer membrane protein
WP7S18E06_32790	COG1666	GTP binding
WP7S18E06_32800	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
WP7S18E06_32810	COG0693	protein deglycase activity
WP7S18E06_32900	COG3501	Rhs element vgr protein
WP7S18E06_32930	COG2771	luxR family
WP7S18E06_32940	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
WP7S18E06_32940	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
WP7S18E06_32950	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
WP7S18E06_32970	COG1151	hydroxylamine reductase activity
WP7S18E06_32980	COG0783	Belongs to the Dps family
WP7S18E06_33030	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
WP7S18E06_33060	COG4221	oxidoreductase activity
WP7S18E06_33080	COG0415	Belongs to the DNA photolyase family
WP7S18E06_33090	COG0789	Transcriptional regulator
WP7S18E06_33100	COG3272	Protein of unknown function (DUF1722)
WP7S18E06_33160	COG0077	Prephenate dehydratase
WP7S18E06_33160	COG1605	Chorismate mutase
WP7S18E06_33210	COG5377	YqaJ viral recombinase family
WP7S18E06_33250	COG4584	PFAM Integrase catalytic
WP7S18E06_33260	COG1484	DNA-dependent DNA replication
WP7S18E06_33320	COG2003	Belongs to the UPF0758 family
WP7S18E06_33360	COG0515	serine threonine protein kinase
WP7S18E06_33360	COG2815	serine threonine protein kinase
WP7S18E06_33450	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
WP7S18E06_33510	COG0840	transmembrane signaling receptor activity
WP7S18E06_33530	COG0300	oxidoreductase activity
WP7S18E06_33580	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
WP7S18E06_33610	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
WP7S18E06_33630	COG0826	peptidase U32
WP7S18E06_33640	COG1280	lysine exporter protein (LysE YggA)
WP7S18E06_33670	COG0840	transmembrane signaling receptor activity
WP7S18E06_33700	COG0643	Histidine kinase
WP7S18E06_33700	COG2198	Histidine kinase
WP7S18E06_33720	COG0835	chemotaxis
WP7S18E06_33730	COG0840	transmembrane signaling receptor activity
WP7S18E06_33750	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
WP7S18E06_33760	COG2201	protein-glutamate methylesterase activity
WP7S18E06_33770	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
WP7S18E06_33800	COG2197	response regulator
WP7S18E06_33810	COG3385	transposase activity
WP7S18E06_33830	COG3188	usher protein
WP7S18E06_33860	COG2199	diguanylate cyclase activity
WP7S18E06_33860	COG2200	EAL domain
WP7S18E06_33860	COG2203	Gaf domain
WP7S18E06_33880	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
WP7S18E06_33890	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
WP7S18E06_33950	COG2200	EAL domain
WP7S18E06_33960	COG0737	Belongs to the 5'-nucleotidase family
WP7S18E06_34000	COG2204	response regulator
WP7S18E06_34010	COG0545	Peptidyl-prolyl cis-trans isomerase
WP7S18E06_34040	COG1047	Peptidyl-prolyl cis-trans
WP7S18E06_34050	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
WP7S18E06_34070	COG0835	chemotaxis
WP7S18E06_34070	COG0784	Response regulator, receiver
WP7S18E06_34080	COG0429	hydrolase of the alpha beta-hydrolase fold
WP7S18E06_34090	COG3706	GGDEF domain
WP7S18E06_34090	COG5001	Diguanylate cyclase
WP7S18E06_34090	COG2203	Gaf domain
WP7S18E06_34090	COG4251	negative regulation of phosphorylation
WP7S18E06_34100	COG3089	Belongs to the UPF0270 family
WP7S18E06_34120	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
WP7S18E06_34130	COG0463	Glycosyl transferase, family 2
WP7S18E06_34140	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
WP7S18E06_34140	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
WP7S18E06_34150	COG0726	polysaccharide deacetylase
WP7S18E06_34160	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
WP7S18E06_34170	COG2076	Multidrug Resistance protein
WP7S18E06_34180	COG2076	Multidrug Resistance protein
WP7S18E06_34190	COG3954	Phosphoribulokinase
WP7S18E06_34220	COG1765	OsmC-like protein
WP7S18E06_34240	COG2226	methyltransferase
WP7S18E06_34250	COG3397	chitin binding
WP7S18E06_34280	COG2202	Pas domain
WP7S18E06_34280	COG2205	protein histidine kinase activity
WP7S18E06_34300	COG3655	Transcriptional regulator
WP7S18E06_34310	COG2814	Major facilitator Superfamily
WP7S18E06_34320	COG4771	TonB-dependent receptor
WP7S18E06_34360	COG0748	coenzyme F420 binding
WP7S18E06_34370	COG3721	Heme iron utilization protein
WP7S18E06_34390	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
WP7S18E06_34440	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
WP7S18E06_34450	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
WP7S18E06_34460	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
WP7S18E06_34500	COG0741	lytic transglycosylase activity
WP7S18E06_34510	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
WP7S18E06_34540	COG0488	(ABC) transporter
WP7S18E06_34560	COG2252	PERMEase
WP7S18E06_34570	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
WP7S18E06_34580	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
WP7S18E06_34590	COG3178	'Phosphotransferase
WP7S18E06_34600	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
WP7S18E06_34620	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
WP7S18E06_34630	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
WP7S18E06_34640	COG2967	ApaG domain
WP7S18E06_34650	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
WP7S18E06_34670	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
WP7S18E06_34680	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
WP7S18E06_34710	COG0318	PFAM AMP-dependent synthetase and ligase
WP7S18E06_34730	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
WP7S18E06_34740	COG0211	Belongs to the bacterial ribosomal protein bL27 family
WP7S18E06_34750	COG0261	This protein binds to 23S rRNA in the presence of protein L20
WP7S18E06_34760	COG0142	geranyltranstransferase activity
WP7S18E06_34770	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
WP7S18E06_34780	COG0330	HflC and HflK could
WP7S18E06_34790	COG0330	HflC and HflK could
WP7S18E06_34800	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
WP7S18E06_34810	COG1923	regulation of RNA biosynthetic process
WP7S18E06_34820	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
WP7S18E06_34830	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
WP7S18E06_34860	COG0802	atpase or kinase
WP7S18E06_34870	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
WP7S18E06_34870	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
WP7S18E06_34880	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
WP7S18E06_34910	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
WP7S18E06_34920	COG2011	ABC-type metal ion transport system permease component
WP7S18E06_34930	COG1464	Belongs to the NlpA lipoprotein family
WP7S18E06_34950	COG0840	transmembrane signaling receptor activity
WP7S18E06_35000	COG5002	protein histidine kinase activity
WP7S18E06_35000	COG2198	Histidine kinase
WP7S18E06_35000	COG0784	Response regulator, receiver
WP7S18E06_35040	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
WP7S18E06_35070	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
WP7S18E06_35080	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
WP7S18E06_35100	COG2716	regulation of RNA biosynthetic process
WP7S18E06_35110	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
WP7S18E06_35120	COG3013	Belongs to the UPF0304 family
WP7S18E06_35140	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
WP7S18E06_35150	COG0857	belongs to the CobB CobQ family
WP7S18E06_35150	COG0280	phosphate acetyltransferase
WP7S18E06_35170	COG0028	Belongs to the TPP enzyme family
WP7S18E06_35190	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
WP7S18E06_35200	COG0671	phosphoesterase, PA-phosphatase related
WP7S18E06_35220	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
WP7S18E06_35230	COG0473	3-isopropylmalate dehydrogenase activity
WP7S18E06_35240	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
WP7S18E06_35250	COG0066	3-isopropylmalate dehydratase activity
WP7S18E06_35280	COG4143	(ABC) transporter
WP7S18E06_35290	COG1178	ABC-type Fe3 transport system permease component
WP7S18E06_35300	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
WP7S18E06_35310	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
WP7S18E06_35330	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
WP7S18E06_35360	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
WP7S18E06_35370	COG0564	pseudouridine synthase activity
WP7S18E06_35380	COG3300	MHYT domain
WP7S18E06_35380	COG5001	Diguanylate cyclase
WP7S18E06_35400	COG0459	protein refolding
WP7S18E06_35410	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
WP7S18E06_35420	COG0534	Mate efflux family protein
WP7S18E06_35430	COG3030	protein affecting phage T7 exclusion by the F plasmid
WP7S18E06_35440	COG1027	Aspartate ammonia-lyase
WP7S18E06_35450	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
WP7S18E06_35470	COG0477	Major facilitator Superfamily
WP7S18E06_35500	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
WP7S18E06_35510	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
WP7S18E06_35530	COG0673	inositol 2-dehydrogenase activity
WP7S18E06_35550	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
WP7S18E06_35560	COG0635	Involved in the biosynthesis of porphyrin-containing compound
WP7S18E06_35570	COG3036	rescue of stalled ribosome
WP7S18E06_35600	COG0138	bifunctional purine biosynthesis protein purh
WP7S18E06_35610	COG0151	Belongs to the GarS family
WP7S18E06_35650	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
WP7S18E06_35660	COG0358	DNA primase activity
WP7S18E06_35670	COG1610	YqeY-like protein
WP7S18E06_35680	COG0828	Belongs to the bacterial ribosomal protein bS21 family
WP7S18E06_35690	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
WP7S18E06_35720	COG1238	metal cluster binding
WP7S18E06_35730	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
WP7S18E06_35740	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
WP7S18E06_35750	COG0585	pseudouridine synthase activity
WP7S18E06_35770	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
WP7S18E06_35780	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
WP7S18E06_35790	COG0148	phosphopyruvate hydratase activity
WP7S18E06_35800	COG0504	CTP synthase activity
WP7S18E06_35810	COG3956	TIGRFAM MazG family protein
WP7S18E06_35820	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
WP7S18E06_35830	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
WP7S18E06_35850	COG4807	Protein conserved in bacteria
WP7S18E06_35860	COG3023	N-Acetylmuramoyl-L-alanine amidase
WP7S18E06_35870	COG1349	DNA-binding transcription factor activity
WP7S18E06_35890	COG2222	sugar isomerase
WP7S18E06_35900	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
WP7S18E06_35920	COG3716	PTS system mannose fructose sorbose family IID component
WP7S18E06_35930	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
WP7S18E06_35940	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
WP7S18E06_35970	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
WP7S18E06_35980	COG1381	Involved in DNA repair and RecF pathway recombination
WP7S18E06_36000	COG0571	ribonuclease III activity
WP7S18E06_36010	COG0681	Belongs to the peptidase S26 family
WP7S18E06_36020	COG0481	GTPase activity
WP7S18E06_36050	COG3073	An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E
WP7S18E06_36060	COG1595	DNA-templated transcription, initiation
WP7S18E06_36070	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
WP7S18E06_36090	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
WP7S18E06_36170	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
WP7S18E06_36190	COG0126	phosphoglycerate kinase activity
WP7S18E06_36200	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
WP7S18E06_36210	COG1940	carbohydrate kinase activity
WP7S18E06_36220	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
WP7S18E06_36250	COG4991	sh3 domain protein
WP7S18E06_36260	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
WP7S18E06_36290	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
WP7S18E06_36300	COG1028	Short-chain dehydrogenase reductase Sdr
WP7S18E06_36330	COG1505	serine-type exopeptidase activity
WP7S18E06_36340	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
WP7S18E06_36350	COG0765	amino acid transport
WP7S18E06_36360	COG0765	amino acid transport
WP7S18E06_36370	COG1126	abc transporter atp-binding protein
WP7S18E06_36380	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
WP7S18E06_36390	COG1136	(ABC) transporter
WP7S18E06_36390	COG0577	efflux transmembrane transporter activity
WP7S18E06_36400	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
WP7S18E06_36410	COG0745	RESPONSE REGULATOR receiver
WP7S18E06_36420	COG2205	protein histidine kinase activity
WP7S18E06_36430	COG2816	NAD+ diphosphatase activity
WP7S18E06_36440	COG2070	2-Nitropropane dioxygenase
WP7S18E06_36490	COG1858	cytochrome C peroxidase
WP7S18E06_36500	COG1912	Pfam S-adenosyl-l-methionine hydroxide adenosyltransferase
WP7S18E06_36540	COG0513	Belongs to the DEAD box helicase family
WP7S18E06_36580	COG0232	Belongs to the dGTPase family. Type 2 subfamily
WP7S18E06_36590	COG0232	Belongs to the dGTPase family. Type 2 subfamily
WP7S18E06_36600	COG0154	amidase activity
WP7S18E06_36610	COG2957	Belongs to the agmatine deiminase family
WP7S18E06_36630	COG2852	Protein conserved in bacteria
WP7S18E06_36650	COG1902	pentaerythritol trinitrate reductase activity
WP7S18E06_36720	COG3300	MHYT domain
WP7S18E06_36720	COG5001	Diguanylate cyclase
WP7S18E06_36740	COG0714	Associated with various cellular activities
WP7S18E06_36760	COG0456	acetyltransferase
WP7S18E06_36780	COG1022	Amp-dependent synthetase and ligase
WP7S18E06_36800	COG2918	glutathione biosynthetic process
WP7S18E06_36810	COG0612	Peptidase, M16
WP7S18E06_36820	COG1238	metal cluster binding
WP7S18E06_36870	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
WP7S18E06_36880	COG0359	binds to the 23S rRNA
WP7S18E06_36890	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
WP7S18E06_36900	COG0360	Binds together with S18 to 16S ribosomal RNA
WP7S18E06_36910	COG1914	H( )-stimulated, divalent metal cation uptake system
WP7S18E06_36920	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
WP7S18E06_36950	COG2153	protein acetylation
WP7S18E06_36970	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
WP7S18E06_36980	COG0557	exoribonuclease II activity
WP7S18E06_36990	COG3706	GGDEF domain
WP7S18E06_37000	COG1854	S-ribosylhomocysteine lyase activity
WP7S18E06_37030	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
WP7S18E06_37030	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
WP7S18E06_37060	COG3385	transposase activity
WP7S18E06_37110	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
WP7S18E06_37120	COG1047	Peptidyl-prolyl cis-trans
WP7S18E06_37130	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
WP7S18E06_37140	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
WP7S18E06_37150	COG0196	riboflavin kinase activity
WP7S18E06_37160	COG0728	peptidoglycan biosynthetic process
WP7S18E06_37170	COG0268	Binds directly to 16S ribosomal RNA
WP7S18E06_37180	COG0640	Transcriptional regulator
WP7S18E06_37190	COG0583	DNA-binding transcription factor activity
WP7S18E06_37210	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
WP7S18E06_37230	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
WP7S18E06_37240	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
WP7S18E06_37260	COG1051	belongs to the nudix hydrolase family
WP7S18E06_37270	COG3066	DNA modification
WP7S18E06_37290	COG0335	large ribosomal subunit rRNA binding
WP7S18E06_37300	COG0336	Belongs to the RNA methyltransferase TrmD family
WP7S18E06_37310	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
WP7S18E06_37320	COG0228	four-way junction DNA binding
WP7S18E06_37330	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
WP7S18E06_37340	COG4137	Cytochrome C assembly protein
WP7S18E06_37350	COG4536	flavin adenine dinucleotide binding
WP7S18E06_37360	COG1959	2 iron, 2 sulfur cluster binding
WP7S18E06_37370	COG1017	nitric oxide dioxygenase activity
WP7S18E06_37370	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
WP7S18E06_37380	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
WP7S18E06_37390	COG0039	L-malate dehydrogenase activity
WP7S18E06_37400	COG4160	amino acid transport
WP7S18E06_37410	COG4215	(ABC) transporter
WP7S18E06_37420	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
WP7S18E06_37430	COG1126	abc transporter atp-binding protein
WP7S18E06_37440	COG1438	arginine binding
WP7S18E06_37450	COG2837	iron assimilation
WP7S18E06_37460	COG3842	ATPase activity
WP7S18E06_37480	COG1840	ABC-type Fe3 transport system, periplasmic component
WP7S18E06_37490	COG0347	Belongs to the P(II) protein family
WP7S18E06_37520	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
WP7S18E06_37530	COG0583	DNA-binding transcription factor activity
WP7S18E06_37560	COG1929	Belongs to the glycerate kinase type-1 family
WP7S18E06_37570	COG2610	gluconate transmembrane transporter activity
WP7S18E06_37580	COG3835	regulator
WP7S18E06_37600	COG3112	Uncharacterised protein family (UPF0231)
WP7S18E06_37630	COG0840	transmembrane signaling receptor activity
WP7S18E06_37670	COG0513	Belongs to the DEAD box helicase family
WP7S18E06_37750	COG1448	Aminotransferase
WP7S18E06_37780	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
WP7S18E06_37790	COG1328	CTP reductase activity
WP7S18E06_37830	COG0793	Belongs to the peptidase S41A family
WP7S18E06_37830	COG4946	Tricorn protease homolog
WP7S18E06_37900	COG3397	chitin binding
WP7S18E06_37910	COG0583	DNA-binding transcription factor activity
WP7S18E06_37920	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
WP7S18E06_37930	COG4208	sulfate ABC transporter
WP7S18E06_37940	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
WP7S18E06_37960	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
WP7S18E06_37970	COG3174	membrane
WP7S18E06_37980	COG0110	maltose O-acetyltransferase activity
WP7S18E06_38030	COG0165	Argininosuccinate lyase
WP7S18E06_38040	COG0137	argininosuccinate synthase activity
WP7S18E06_38060	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
WP7S18E06_38070	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
WP7S18E06_38090	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
WP7S18E06_38100	COG0460	homoserine dehydrogenase
WP7S18E06_38100	COG0527	aspartate kinase activity
WP7S18E06_38110	COG0626	cystathionine gamma-synthase activity
WP7S18E06_38130	COG3708	Transcriptional regulator
WP7S18E06_38130	COG2207	Transcriptional regulator
WP7S18E06_38140	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
WP7S18E06_38150	COG0814	amino acid
WP7S18E06_38160	COG1218	3'(2'),5'-bisphosphate nucleotidase
WP7S18E06_38170	COG0494	nUDIX hydrolase
WP7S18E06_38180	COG1011	Hydrolase
WP7S18E06_38190	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
WP7S18E06_38220	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
WP7S18E06_38240	COG3156	type II secretion system protein K
WP7S18E06_38250	COG4795	General secretion pathway protein
WP7S18E06_38260	COG2165	general secretion pathway protein
WP7S18E06_38280	COG2165	general secretion pathway protein
WP7S18E06_38290	COG1459	type II secretion system
WP7S18E06_38300	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
WP7S18E06_38320	COG3031	protein transport across the cell outer membrane
WP7S18E06_38340	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
WP7S18E06_38390	COG0456	acetyltransferase
WP7S18E06_38400	COG3133	Outer membrane lipoprotein
WP7S18E06_38430	COG2771	luxR family
WP7S18E06_38440	COG3916	Acyl-homoserine-lactone synthase
WP7S18E06_38460	COG4776	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction
WP7S18E06_38470	COG1309	transcriptional regulator
WP7S18E06_38490	COG2213	PTS system mannitol-specific
WP7S18E06_38490	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
WP7S18E06_38500	COG0246	Mannitol dehydrogenase
WP7S18E06_38510	COG3722	fumarate hydratase activity
WP7S18E06_38520	COG3263	regulation of cellular component size
WP7S18E06_38570	COG1671	Belongs to the UPF0178 family
WP7S18E06_38600	COG1988	membrane-bound metal-dependent
WP7S18E06_38610	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
WP7S18E06_38620	COG0513	Belongs to the DEAD box helicase family
WP7S18E06_38670	COG1575	Belongs to the MenA family. Type 1 subfamily
WP7S18E06_38680	COG1169	isochorismate synthase
WP7S18E06_38690	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
WP7S18E06_38700	COG0596	Alpha beta hydrolase
WP7S18E06_38710	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
WP7S18E06_38720	COG1441	menaquinone biosynthetic process
WP7S18E06_38730	COG0318	PFAM AMP-dependent synthetase and ligase
WP7S18E06_38760	COG3539	Fimbrial protein
WP7S18E06_38770	COG3121	Chaperone
WP7S18E06_38780	COG3188	usher protein
WP7S18E06_38820	COG3291	Pkd domain containing protein
WP7S18E06_38830	COG2949	membrane
WP7S18E06_38840	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
WP7S18E06_38860	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
WP7S18E06_38870	COG5380	lipid catabolic process
WP7S18E06_38900	COG4533	DNA binding
WP7S18E06_38920	COG2873	o-acetylhomoserine
WP7S18E06_38940	COG1979	alcohol dehydrogenase
WP7S18E06_38980	COG4221	oxidoreductase activity
WP7S18E06_39020	COG1285	pathogenesis
WP7S18E06_39060	COG1368	sulfuric ester hydrolase activity
WP7S18E06_39070	COG1522	sequence-specific DNA binding
WP7S18E06_39090	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
WP7S18E06_39100	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
WP7S18E06_39110	COG1546	Belongs to the CinA family
WP7S18E06_39110	COG1058	Belongs to the CinA family
WP7S18E06_39130	COG1129	ABC transporter
WP7S18E06_39130	COG0842	Transport permease protein
WP7S18E06_39160	COG0561	phosphatase activity
WP7S18E06_39170	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
WP7S18E06_39210	COG1011	Hydrolase
WP7S18E06_39240	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
WP7S18E06_39250	COG0019	diaminopimelate decarboxylase activity
WP7S18E06_39260	COG1965	Belongs to the frataxin family
WP7S18E06_39270	COG0400	carboxylic ester hydrolase activity
WP7S18E06_39280	COG3072	Adenylate cyclase
WP7S18E06_39290	COG0181	hydroxymethylbilane synthase activity
WP7S18E06_39310	COG2959	enzyme of heme biosynthesis
WP7S18E06_39340	COG1494	fructose-1,6-bisphosphatase
WP7S18E06_39420	COG1733	regulation of RNA biosynthetic process
WP7S18E06_39460	COG3932	Exopolysaccharide synthesis, ExoD
WP7S18E06_39470	COG0814	amino acid
WP7S18E06_39480	COG3706	GGDEF domain
WP7S18E06_39520	COG3417	Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1B (PBP1b)
WP7S18E06_39550	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
WP7S18E06_39560	COG2022	thiamine diphosphate biosynthetic process
WP7S18E06_39580	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
WP7S18E06_39590	COG0352	thiamine-phosphate diphosphorylase activity
WP7S18E06_39600	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
WP7S18E06_39650	COG0745	RESPONSE REGULATOR receiver
WP7S18E06_39660	COG0642	Histidine kinase
WP7S18E06_39680	COG0189	ligase activity
WP7S18E06_39730	COG1639	'signal transduction protein
WP7S18E06_39750	COG2321	neutral zinc metallopeptidase
WP7S18E06_39760	COG3700	Belongs to the class B bacterial acid phosphatase family
WP7S18E06_39810	COG2172	sigma factor antagonist activity
WP7S18E06_39820	COG5002	protein histidine kinase activity
WP7S18E06_39820	COG0784	Response regulator, receiver
WP7S18E06_39820	COG2205	protein histidine kinase activity
WP7S18E06_39830	COG3437	response regulator, receiver
WP7S18E06_39850	COG0477	Major facilitator Superfamily
WP7S18E06_39880	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
WP7S18E06_39890	COG1263	PTS System
WP7S18E06_39890	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
WP7S18E06_39930	COG0312	modulator of DNA gyrase
WP7S18E06_39940	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
WP7S18E06_39960	COG3164	Protein of unknown function
WP7S18E06_39970	COG1530	ribonuclease E activity
WP7S18E06_39980	COG0424	maF-like protein
WP7S18E06_39990	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
WP7S18E06_40000	COG1792	Involved in formation and maintenance of cell shape
WP7S18E06_40010	COG1077	Cell shape determining protein MreB Mrl
WP7S18E06_40060	COG2165	general secretion pathway protein
WP7S18E06_40100	COG1459	type II secretion system
WP7S18E06_40110	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
WP7S18E06_40200	COG2200	EAL domain
WP7S18E06_40200	COG2199	diguanylate cyclase activity
WP7S18E06_40210	COG2200	EAL domain
WP7S18E06_40220	COG0387	Pfam Sodium calcium exchanger
WP7S18E06_40230	COG2986	histidine ammonia-lyase
WP7S18E06_40240	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
WP7S18E06_40250	COG0010	Belongs to the arginase family
WP7S18E06_40260	COG1228	amidohydrolase
WP7S18E06_40270	COG2188	Transcriptional regulator
WP7S18E06_40280	COG0288	reversible hydration of carbon dioxide
WP7S18E06_40300	COG2177	Part of the ABC transporter FtsEX involved in
WP7S18E06_40310	COG2884	Cell division ATP-binding protein ftsE
WP7S18E06_40320	COG0552	protein localization to endoplasmic reticulum
WP7S18E06_40330	COG0742	ribosomal rna small subunit methyltransferase
WP7S18E06_40380	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
WP7S18E06_40400	COG0741	lytic transglycosylase activity
WP7S18E06_40420	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
WP7S18E06_40440	COG2095	MarC family integral membrane protein
WP7S18E06_40460	COG1301	dicarboxylic acid transport
WP7S18E06_40510	COG3714	YhhN family
WP7S18E06_40560	COG1770	oligopeptidase
WP7S18E06_40590	COG4221	oxidoreductase activity
WP7S18E06_40600	COG0583	DNA-binding transcription factor activity
WP7S18E06_40610	COG2249	NAD(P)H dehydrogenase (quinone) activity
WP7S18E06_40650	COG0203	ribosomal protein L17
WP7S18E06_40660	COG0202	RNA polymerase activity
WP7S18E06_40670	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
WP7S18E06_40680	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
WP7S18E06_40690	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
WP7S18E06_40700	COG0201	protein transport
WP7S18E06_40710	COG0200	Binds to the 23S rRNA
WP7S18E06_40720	COG1841	ribosomal large subunit assembly
WP7S18E06_40730	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
WP7S18E06_40740	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
WP7S18E06_40750	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
WP7S18E06_40760	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
WP7S18E06_40770	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
WP7S18E06_40780	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
WP7S18E06_40790	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
WP7S18E06_40800	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
WP7S18E06_40810	COG0255	Belongs to the universal ribosomal protein uL29 family
WP7S18E06_40820	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
WP7S18E06_40830	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
WP7S18E06_40840	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
WP7S18E06_40850	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
WP7S18E06_40860	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
WP7S18E06_40870	COG0089	rRNA binding
WP7S18E06_40880	COG0088	Forms part of the polypeptide exit tunnel
WP7S18E06_40890	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
WP7S18E06_40900	COG0051	transcription antitermination factor activity, RNA binding
WP7S18E06_40930	COG0745	RESPONSE REGULATOR receiver
WP7S18E06_40940	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
WP7S18E06_40950	COG2183	response to ionizing radiation
WP7S18E06_40990	COG0596	Alpha beta hydrolase
WP7S18E06_41000	COG1040	competence protein
WP7S18E06_41010	COG0316	Belongs to the HesB IscA family
WP7S18E06_41010	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
WP7S18E06_41020	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
WP7S18E06_41030	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
WP7S18E06_41040	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
WP7S18E06_41050	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
WP7S18E06_41060	COG4942	peptidase
WP7S18E06_41080	COG1609	Transcriptional regulator
WP7S18E06_41090	COG0800	Aldolase
WP7S18E06_41100	COG0129	dihydroxy-acid dehydratase activity
WP7S18E06_41110	COG3265	gluconokinase activity
WP7S18E06_41120	COG2610	gluconate transmembrane transporter activity
WP7S18E06_41130	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
WP7S18E06_41140	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
WP7S18E06_41160	COG0456	acetyltransferase
WP7S18E06_41190	COG1490	D-aminoacyl-tRNA deacylase activity
WP7S18E06_41200	COG1295	ribonuclease BN
WP7S18E06_41220	COG0174	glutamine synthetase
WP7S18E06_41240	COG3852	Histidine kinase
WP7S18E06_41250	COG2204	response regulator
WP7S18E06_41260	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
WP7S18E06_41270	COG0635	Involved in the biosynthesis of porphyrin-containing compound
WP7S18E06_41290	COG3078	GTPase activator activity
WP7S18E06_41310	COG0218	Necessary for normal cell division and for the maintenance of normal septation
WP7S18E06_41330	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
WP7S18E06_41340	COG0408	coproporphyrinogen oxidase activity
WP7S18E06_41350	COG0009	L-threonylcarbamoyladenylate synthase
WP7S18E06_41370	COG0551	DNA topoisomerase type I activity
WP7S18E06_41380	COG2922	Belongs to the Smg family
WP7S18E06_41390	COG0758	DNA mediated transformation
WP7S18E06_41410	COG0242	peptide deformylase activity
WP7S18E06_41420	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
WP7S18E06_41430	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
WP7S18E06_41430	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
WP7S18E06_41440	COG0569	domain protein
WP7S18E06_41450	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
WP7S18E06_41460	COG1322	Protein conserved in bacteria
WP7S18E06_41500	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
WP7S18E06_41510	COG0686	Belongs to the AlaDH PNT family
WP7S18E06_41520	COG0519	Catalyzes the synthesis of GMP from XMP
WP7S18E06_41520	COG0518	GMP synthase (glutamine-hydrolyzing) activity
WP7S18E06_41550	COG1396	sequence-specific DNA binding
WP7S18E06_41560	COG1012	belongs to the aldehyde dehydrogenase family
WP7S18E06_41580	COG2962	Rard protein
WP7S18E06_41600	COG1280	lysine exporter protein (LysE YggA)
WP7S18E06_41620	COG0840	transmembrane signaling receptor activity
WP7S18E06_41630	COG2391	methyltransferase activity
WP7S18E06_41640	COG1280	lysine exporter protein (LysE YggA)
WP7S18E06_41750	COG0583	DNA-binding transcription factor activity
WP7S18E06_41760	COG1943	Transposase
WP7S18E06_41800	COG0210	DNA helicase
WP7S18E06_41880	COG0583	DNA-binding transcription factor activity
WP7S18E06_41920	COG1262	PFAM Formylglycine-generating sulfatase enzyme
WP7S18E06_41930	COG0385	Bile acid
WP7S18E06_41940	COG0531	amino acid
WP7S18E06_41950	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
WP7S18E06_41960	COG0531	amino acid
WP7S18E06_41970	COG2731	YhcH YjgK YiaL family protein
WP7S18E06_41980	COG3250	beta-galactosidase activity
WP7S18E06_41990	COG1609	Transcriptional regulator
WP7S18E06_42000	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
WP7S18E06_42010	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
WP7S18E06_42010	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
WP7S18E06_42020	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
WP7S18E06_42030	COG3074	FtsZ-dependent cytokinesis
WP7S18E06_42050	COG1045	serine acetyltransferase
WP7S18E06_42070	COG0745	RESPONSE REGULATOR receiver
WP7S18E06_42080	COG2205	protein histidine kinase activity
WP7S18E06_42090	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
WP7S18E06_42100	COG0534	Mate efflux family protein
WP7S18E06_42130	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
WP7S18E06_42140	COG2937	Belongs to the GPAT DAPAT family
WP7S18E06_42150	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
WP7S18E06_42160	COG3161	chorismate lyase activity
WP7S18E06_42170	COG1580	Controls the rotational direction of flagella during chemotaxis
WP7S18E06_42210	COG0604	alcohol dehydrogenase
WP7S18E06_42220	COG1609	Transcriptional regulator
WP7S18E06_42260	COG1519	Transferase
WP7S18E06_42270	COG0859	PFAM glycosyl transferase family 9
WP7S18E06_42280	COG0463	Glycosyl transferase, family 2
WP7S18E06_42290	COG0859	PFAM glycosyl transferase family 9
WP7S18E06_42300	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
WP7S18E06_42310	COG2990	Protein conserved in bacteria
WP7S18E06_42320	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
WP7S18E06_42340	COG0267	Belongs to the bacterial ribosomal protein bL33 family
WP7S18E06_42350	COG0227	Belongs to the bacterial ribosomal protein bL28 family
WP7S18E06_42360	COG2003	Belongs to the UPF0758 family
WP7S18E06_42370	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
WP7S18E06_42380	COG0756	dUTP diphosphatase activity
WP7S18E06_42390	COG1309	transcriptional regulator
WP7S18E06_42400	COG0668	transmembrane transport
WP7S18E06_42420	COG0166	Belongs to the GPI family
WP7S18E06_42430	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
WP7S18E06_42440	COG0583	DNA-binding transcription factor activity
WP7S18E06_42480	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
WP7S18E06_42490	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
WP7S18E06_42500	COG1739	Uncharacterized protein family UPF0029
WP7S18E06_42510	COG0006	proline dipeptidase activity
WP7S18E06_42520	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
WP7S18E06_42530	COG1024	Enoyl-CoA hydratase
WP7S18E06_42530	COG1250	3-hydroxyacyl-CoA dehydrogenase
WP7S18E06_42540	COG0183	Belongs to the thiolase family
WP7S18E06_42550	COG0745	RESPONSE REGULATOR receiver
WP7S18E06_42560	COG2205	protein histidine kinase activity
WP7S18E06_42590	COG0425	Belongs to the sulfur carrier protein TusA family
WP7S18E06_42600	COG0251	oxidation-reduction process
WP7S18E06_42610	COG2885	chlorophyll binding
WP7S18E06_42630	COG2818	Glycosylase
WP7S18E06_42640	COG0752	glycyl-tRNA synthetase alpha subunit
WP7S18E06_42650	COG0751	glycine-tRNA ligase activity
WP7S18E06_42670	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
WP7S18E06_42700	COG0583	DNA-binding transcription factor activity
WP7S18E06_42740	COG0814	amino acid
WP7S18E06_42750	COG0348	domain, Protein
WP7S18E06_42770	COG0446	pyridine nucleotide-disulphide oxidoreductase
WP7S18E06_42780	COG0426	domain, Protein
WP7S18E06_42780	COG1773	rubredoxin
WP7S18E06_42790	COG3604	Transcriptional regulator
WP7S18E06_42800	COG2188	Transcriptional regulator
WP7S18E06_42830	COG1609	Transcriptional regulator
WP7S18E06_42910	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
WP7S18E06_42960	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
WP7S18E06_42990	COG3118	belongs to the thioredoxin family
WP7S18E06_43000	COG0513	Belongs to the DEAD box helicase family
WP7S18E06_43010	COG0248	Ppx GppA phosphatase
WP7S18E06_43030	COG0742	ribosomal rna small subunit methyltransferase
WP7S18E06_43070	COG0084	hydrolase, TatD family'
WP7S18E06_43080	COG0805	protein transport
WP7S18E06_43090	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
WP7S18E06_43110	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
WP7S18E06_43120	COG3165	ubiquinone biosynthetic process from chorismate
WP7S18E06_43140	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
WP7S18E06_43150	COG0402	S-adenosylhomocysteine deaminase activity
WP7S18E06_43180	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
WP7S18E06_43190	COG0848	biopolymer transport protein
WP7S18E06_43200	COG0811	peptide transport
WP7S18E06_43210	COG0811	peptide transport
WP7S18E06_43230	COG2771	luxR family
WP7S18E06_43240	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
WP7S18E06_43250	COG1349	DNA-binding transcription factor activity
WP7S18E06_43260	COG0745	RESPONSE REGULATOR receiver
WP7S18E06_43270	COG2205	protein histidine kinase activity
WP7S18E06_43290	COG4452	Inner membrane protein CreD
WP7S18E06_43300	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
WP7S18E06_43310	COG0355	proton-transporting ATP synthase activity, rotational mechanism
WP7S18E06_43320	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
WP7S18E06_43330	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
WP7S18E06_43340	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
WP7S18E06_43350	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
WP7S18E06_43360	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
WP7S18E06_43380	COG0356	it plays a direct role in the translocation of protons across the membrane
WP7S18E06_43400	COG1475	DNA binding
WP7S18E06_43410	COG1192	Involved in chromosome partitioning
WP7S18E06_43420	COG0357	Ribosomal RNA small subunit methyltransferase G
WP7S18E06_43430	COG0445	tRNA wobble uridine modification
WP7S18E06_43440	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
WP7S18E06_43450	COG4774	siderophore transport
WP7S18E06_43460	COG4615	Cyclic peptide transporter
WP7S18E06_43470	COG1120	ATPase activity
WP7S18E06_43500	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
WP7S18E06_43510	COG0706	membrane insertase activity
WP7S18E06_43520	COG0594	ribonuclease P activity
WP7S18E06_43530	COG0230	Belongs to the bacterial ribosomal protein bL34 family