locus-tag	class	description
BFW97_00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
BFW97_00010	COG0592	DNA-directed DNA polymerase activity
BFW97_00020	COG0187	DNA topoisomerase II activity
BFW97_00030	COG2378	regulation of single-species biofilm formation
BFW97_00035	COG0071	Belongs to the small heat shock protein (HSP20) family
BFW97_00040	COG0071	Belongs to the small heat shock protein (HSP20) family
BFW97_00045	COG3977	Valine--pyruvate aminotransferase
BFW97_00060	COG2814	Major facilitator Superfamily
BFW97_00065	COG0745	RESPONSE REGULATOR receiver
BFW97_00070	COG2205	protein histidine kinase activity
BFW97_00100	COG3550	peptidyl-serine autophosphorylation
BFW97_00125	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BFW97_00130	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BFW97_00130	COG4191	Histidine kinase
BFW97_00135	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BFW97_00140	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BFW97_00145	COG1309	transcriptional regulator
BFW97_00175	COG0469	pyruvate kinase activity
BFW97_00180	COG2271	Major facilitator Superfamily
BFW97_00185	COG1840	ABC-type Fe3 transport system, periplasmic component
BFW97_00205	COG0561	phosphatase activity
BFW97_00210	COG2267	carboxylic ester hydrolase activity
BFW97_00220	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BFW97_00225	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
BFW97_00230	COG1758	RNA polymerase activity
BFW97_00240	COG0859	PFAM glycosyl transferase family 9
BFW97_00245	COG3642	lipopolysaccharide core region biosynthetic process
BFW97_00280	COG0589	response to stress
BFW97_00285	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
BFW97_00290	COG2199	diguanylate cyclase activity
BFW97_00295	COG1528	Iron-storage protein
BFW97_00300	COG2081	HI0933 family
BFW97_00305	COG2223	nitrite transmembrane transporter activity
BFW97_00325	COG3188	usher protein
BFW97_00345	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BFW97_00345	COG2205	protein histidine kinase activity
BFW97_00355	COG3275	phosphorelay sensor kinase activity
BFW97_00360	COG3279	Response regulator of the LytR AlgR family
BFW97_00365	COG2223	nitrite transmembrane transporter activity
BFW97_00370	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
BFW97_00375	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
BFW97_00390	COG0583	DNA-binding transcription factor activity
BFW97_00395	COG4206	TonB-dependent receptor
BFW97_00400	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
BFW97_00435	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
BFW97_00440	COG2166	iron-sulfur cluster assembly
BFW97_00445	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
BFW97_00450	COG0210	DNA helicase
BFW97_00460	COG3245	cytochrome
BFW97_00465	COG1063	alcohol dehydrogenase
BFW97_00470	COG0156	8-amino-7-oxononanoate synthase activity
BFW97_00480	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BFW97_00495	COG3306	glycosyltransferase involved in LPS biosynthesis
BFW97_00515	COG1561	YicC-like family, N-terminal region
BFW97_00520	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
BFW97_00525	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
BFW97_00535	COG0789	Transcriptional regulator
BFW97_00540	COG4251	negative regulation of phosphorylation
BFW97_00540	COG5001	Diguanylate cyclase
BFW97_00540	COG3706	GGDEF domain
BFW97_00540	COG2203	Gaf domain
BFW97_00545	COG3084	Protein conserved in bacteria
BFW97_00555	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
BFW97_00560	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
BFW97_00565	COG3639	organic phosphonate transmembrane transporter activity
BFW97_00570	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
BFW97_00575	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
BFW97_00585	COG1335	isochorismatase
BFW97_00595	COG1683	Conserved Protein
BFW97_00600	COG0204	Acyl-transferase
BFW97_00605	COG0204	Acyl-transferase
BFW97_00610	COG0606	chelatase, subunit chli
BFW97_00620	COG3978	acetolactate synthase activity
BFW97_00625	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BFW97_00630	COG0129	dihydroxy-acid dehydratase activity
BFW97_00650	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
BFW97_00655	COG0254	rRNA binding
BFW97_00660	COG0702	epimerase
BFW97_00665	COG0281	malic enzyme
BFW97_00675	COG2205	protein histidine kinase activity
BFW97_00680	COG0745	RESPONSE REGULATOR receiver
BFW97_00685	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
BFW97_00700	COG0366	Alpha amylase catalytic
BFW97_00715	COG0443	Heat shock 70 kDa protein
BFW97_00720	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BFW97_00725	COG3045	CreA protein
BFW97_00740	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
BFW97_00745	COG0174	glutamine synthetase
BFW97_00765	COG3842	ATPase activity
BFW97_00770	COG1176	ABC-type spermidine putrescine transport system, permease component I
BFW97_00775	COG1177	transmembrane transport
BFW97_00780	COG2258	MOSC domain
BFW97_00795	COG2050	protein possibly involved in aromatic compounds catabolism
BFW97_00800	COG0514	ATP-dependent DNA helicase (RecQ)
BFW97_00810	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
BFW97_00820	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
BFW97_00825	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
BFW97_00835	COG2239	Acts as a magnesium transporter
BFW97_00840	COG1648	precorrin-2 dehydrogenase activity
BFW97_00840	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
BFW97_00845	COG2116	formate transmembrane transporter activity
BFW97_00850	COG2146	nitrite reductase [NAD(P)H] activity
BFW97_00855	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BFW97_00870	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
BFW97_00875	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
BFW97_00895	COG1595	DNA-templated transcription, initiation
BFW97_00900	COG3806	Anti-sigma factor
BFW97_00905	COG1968	undecaprenyl-diphosphatase activity
BFW97_00910	COG0667	Aldo Keto reductase
BFW97_00915	COG2017	converts alpha-aldose to the beta-anomer
BFW97_00920	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
BFW97_00930	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
BFW97_00935	COG1609	Transcriptional regulator
BFW97_00940	COG3250	beta-galactosidase activity
BFW97_00960	COG0840	transmembrane signaling receptor activity
BFW97_00985	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
BFW97_00990	COG1288	antiporter activity
BFW97_00995	COG1438	arginine binding
BFW97_01000	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
BFW97_01005	COG0540	Belongs to the ATCase OTCase family
BFW97_01020	COG0688	phosphatidylethanolamine metabolic process
BFW97_01035	COG2207	Transcriptional regulator
BFW97_01040	COG1979	alcohol dehydrogenase
BFW97_01045	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
BFW97_01050	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
BFW97_01060	COG2964	Protein conserved in bacteria
BFW97_01065	COG3681	Belongs to the UPF0597 family
BFW97_01075	COG0446	pyridine nucleotide-disulphide oxidoreductase
BFW97_01080	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BFW97_01085	COG0564	pseudouridine synthase activity
BFW97_01095	COG0542	response to heat
BFW97_01100	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
BFW97_01105	COG2502	aspartate--ammonia ligase
BFW97_01110	COG1522	sequence-specific DNA binding
BFW97_01120	COG5413	integral membrane protein
BFW97_01140	COG2205	protein histidine kinase activity
BFW97_01150	COG2204	response regulator
BFW97_01165	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
BFW97_01180	COG0745	RESPONSE REGULATOR receiver
BFW97_01185	COG2205	protein histidine kinase activity
BFW97_01195	COG0243	molybdopterin cofactor binding
BFW97_01200	COG3005	denitrification pathway
BFW97_01205	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
BFW97_01225	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
BFW97_01230	COG0569	domain protein
BFW97_01235	COG0812	UDP-N-acetylmuramate dehydrogenase activity
BFW97_01260	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
BFW97_01270	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
BFW97_01275	COG0250	Participates in transcription elongation, termination and antitermination
BFW97_01280	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
BFW97_01285	COG0081	regulation of translation
BFW97_01290	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
BFW97_01295	COG0222	ribosome binding
BFW97_01300	COG0085	RNA polymerase activity
BFW97_01305	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
BFW97_01315	COG2964	Protein conserved in bacteria
BFW97_01320	COG0251	oxidation-reduction process
BFW97_01330	COG2923	Belongs to the DsrF TusC family
BFW97_01335	COG2168	tRNA wobble position uridine thiolation
BFW97_01345	COG0049	tRNA binding
BFW97_01350	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
BFW97_01355	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
BFW97_01360	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
BFW97_01400	COG2252	PERMEase
BFW97_01405	COG2376	Dihydroxyacetone kinase
BFW97_01410	COG1461	Dihydroxyacetone kinase
BFW97_01425	COG3284	Transcriptional regulator
BFW97_01435	COG2957	Belongs to the agmatine deiminase family
BFW97_01440	COG4221	oxidoreductase activity
BFW97_01445	COG0628	permease
BFW97_01450	COG0494	nUDIX hydrolase
BFW97_01475	COG0753	catalase activity
BFW97_01480	COG1247	-acetyltransferase
BFW97_01500	COG3706	GGDEF domain
BFW97_01510	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
BFW97_01520	COG1175	transmembrane transport
BFW97_01545	COG0583	DNA-binding transcription factor activity
BFW97_01555	COG1741	Belongs to the pirin family
BFW97_01560	COG2259	Doxx family
BFW97_01565	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
BFW97_01570	COG1074	ATP-dependent DNA helicase activity
BFW97_01575	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
BFW97_01585	COG0346	lactoylglutathione lyase activity
BFW97_01620	COG0745	RESPONSE REGULATOR receiver
BFW97_01625	COG2205	protein histidine kinase activity
BFW97_01630	COG2203	Gaf domain
BFW97_01630	COG3706	GGDEF domain
BFW97_01630	COG5001	Diguanylate cyclase
BFW97_01630	COG4251	negative regulation of phosphorylation
BFW97_01635	COG4771	TonB-dependent receptor
BFW97_01640	COG1278	Cold shock
BFW97_01660	COG0629	single-stranded DNA binding
BFW97_01665	COG2197	response regulator
BFW97_01670	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
BFW97_01680	COG3047	cAMP biosynthetic process
BFW97_01685	COG0840	transmembrane signaling receptor activity
BFW97_01710	COG3135	benzoate transporter
BFW97_01715	COG1396	sequence-specific DNA binding
BFW97_01750	COG2926	Belongs to the UPF0265 family
BFW97_01760	COG3028	Belongs to the UPF0307 family
BFW97_01765	COG0312	modulator of DNA gyrase
BFW97_01770	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
BFW97_01775	COG5007	Belongs to the BolA IbaG family
BFW97_01785	COG2854	intermembrane phospholipid transfer
BFW97_01790	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
BFW97_01795	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
BFW97_01800	COG1127	ABC transporter
BFW97_01805	COG0517	IMP dehydrogenase activity
BFW97_01805	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
BFW97_01810	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
BFW97_01815	COG3117	lipopolysaccharide transmembrane transporter activity
BFW97_01820	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
BFW97_01825	COG1137	ATPase activity
BFW97_01830	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
BFW97_01840	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BFW97_01845	COG1660	Displays ATPase and GTPase activities
BFW97_01850	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
BFW97_01855	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BFW97_01855	COG3711	transcriptional antiterminator
BFW97_01870	COG3964	amidohydrolase
BFW97_01900	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BFW97_01905	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BFW97_01915	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
BFW97_01920	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
BFW97_01925	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
BFW97_01930	COG0723	plastoquinol--plastocyanin reductase activity
BFW97_01935	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
BFW97_01940	COG2857	Cytochrome c1
BFW97_01945	COG0625	glutathione transferase activity
BFW97_01950	COG2969	positive regulation of protein catabolic process
BFW97_01955	COG2823	Periplasmic or secreted lipoprotein
BFW97_01960	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
BFW97_01965	COG0792	nuclease activity
BFW97_01970	COG3107	peptidoglycan biosynthetic process
BFW97_01975	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
BFW97_01985	COG2001	Belongs to the MraZ family
BFW97_01990	COG0275	rRNA processing
BFW97_01995	COG3116	cell division
BFW97_02000	COG0768	penicillin binding
BFW97_02010	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
BFW97_02015	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
BFW97_02020	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
BFW97_02025	COG0772	Belongs to the SEDS family
BFW97_02030	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
BFW97_02035	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
BFW97_02040	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
BFW97_02045	COG0849	cell division
BFW97_02050	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
BFW97_02055	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
BFW97_02065	COG0653	protein targeting
BFW97_02075	COG0494	nUDIX hydrolase
BFW97_02080	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
BFW97_02085	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
BFW97_02100	COG1459	type II secretion system
BFW97_02105	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
BFW97_02130	COG2186	Transcriptional regulator
BFW97_02135	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
BFW97_02140	COG0508	dehydrogenase complex catalyzes the overall conversion of
BFW97_02145	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BFW97_02150	COG5002	protein histidine kinase activity
BFW97_02150	COG3447	MASE1 domain protein
BFW97_02150	COG5001	Diguanylate cyclase
BFW97_02160	COG0840	transmembrane signaling receptor activity
BFW97_02165	COG0840	transmembrane signaling receptor activity
BFW97_02170	COG1752	Esterase of the alpha-beta hydrolase superfamily
BFW97_02175	COG1049	propionate catabolic process, 2-methylcitrate cycle
BFW97_02190	COG1280	lysine exporter protein (LysE YggA)
BFW97_02200	COG0523	cobalamin synthesis protein
BFW97_02205	COG0477	Major facilitator Superfamily
BFW97_02220	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
BFW97_02225	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
BFW97_02270	COG0835	chemotaxis
BFW97_02270	COG0784	Response regulator, receiver
BFW97_02275	COG1028	Short-chain dehydrogenase reductase Sdr
BFW97_02280	COG1444	tRNA N-acetyltransferase activity
BFW97_02305	COG1803	Methylglyoxal synthase
BFW97_02320	COG0252	asparaginase activity
BFW97_02340	COG1263	PTS System
BFW97_02340	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BFW97_02345	COG0366	Alpha amylase catalytic
BFW97_02350	COG0110	maltose O-acetyltransferase activity
BFW97_02355	COG1522	sequence-specific DNA binding
BFW97_02360	COG5006	permease, DMT superfamily
BFW97_02370	COG1012	belongs to the aldehyde dehydrogenase family
BFW97_02375	COG1177	transmembrane transport
BFW97_02380	COG1176	ABC-type spermidine putrescine transport system, permease component I
BFW97_02385	COG3842	ATPase activity
BFW97_02390	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
BFW97_02395	COG0583	DNA-binding transcription factor activity
BFW97_02400	COG1757	Na H antiporter
BFW97_02440	COG0297	glycogen (starch) synthase activity
BFW97_02445	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
BFW97_02450	COG2813	Specifically methylates the guanine in position
BFW97_02455	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BFW97_02460	COG5001	Diguanylate cyclase
BFW97_02460	COG4251	negative regulation of phosphorylation
BFW97_02460	COG2203	Gaf domain
BFW97_02460	COG3706	GGDEF domain
BFW97_02470	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BFW97_02480	COG2995	paraquat-inducible protein a
BFW97_02485	COG3008	intermembrane lipid transfer
BFW97_02485	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
BFW97_02490	COG3009	Protein conserved in bacteria
BFW97_02495	COG2885	chlorophyll binding
BFW97_02495	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
BFW97_02505	COG3240	lipase activity
BFW97_02510	COG3111	PFAM Bacterial OB fold (BOF) protein
BFW97_02520	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
BFW97_02525	COG1194	a g-specific adenine glycosylase
BFW97_02535	COG3409	Peptidoglycan-binding domain 1 protein
BFW97_02535	COG3267	Type II secretory pathway component ExeA
BFW97_02545	COG0617	tRNA 3'-terminal CCA addition
BFW97_02560	COG1346	cytolysis
BFW97_02565	COG1380	Effector of murein hydrolase LrgA
BFW97_02570	COG0583	DNA-binding transcription factor activity
BFW97_02595	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
BFW97_02600	COG0306	phosphate transporter
BFW97_02605	COG1392	Phosphate transport regulator
BFW97_02620	COG1560	Kdo2-lipid A biosynthetic process
BFW97_02625	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
BFW97_02625	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
BFW97_02630	COG1538	Outer membrane efflux protein
BFW97_02635	COG0494	nUDIX hydrolase
BFW97_02640	COG3151	Protein conserved in bacteria
BFW97_02650	COG3150	esterase
BFW97_02655	COG1051	belongs to the nudix hydrolase family
BFW97_02670	COG1566	PFAM secretion protein HlyD family protein
BFW97_02675	COG1289	transmembrane transporter activity
BFW97_02680	COG0187	DNA topoisomerase II activity
BFW97_02725	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BFW97_02750	COG0204	Acyl-transferase
BFW97_02755	COG1842	Phage shock protein A
BFW97_02770	COG2827	Endonuclease containing a URI domain
BFW97_02780	COG2962	Rard protein
BFW97_02785	COG1573	uracil-dna glycosylase
BFW97_02790	COG0697	spore germination
BFW97_02800	COG1108	ABC-type Mn2 Zn2 transport systems permease components
BFW97_02805	COG1121	(ABC) transporter
BFW97_02810	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
BFW97_02830	COG0739	heme binding
BFW97_02840	COG3068	Protein conserved in bacteria
BFW97_02860	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
BFW97_02865	COG0582	viral genome integration into host DNA
BFW97_02885	COG1546	Belongs to the CinA family
BFW97_02890	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
BFW97_02900	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
BFW97_02905	COG0527	aspartate kinase activity
BFW97_02910	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
BFW97_02945	COG1686	Belongs to the peptidase S11 family
BFW97_02950	COG0586	Pfam SNARE associated Golgi protein
BFW97_02955	COG1253	flavin adenine dinucleotide binding
BFW97_02960	COG0525	valine-tRNA ligase activity
BFW97_02965	COG2927	DNA polymerase III (CHI subunit)
BFW97_02970	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
BFW97_02975	COG0795	lipopolysaccharide-transporting ATPase activity
BFW97_02980	COG0795	lipopolysaccharide-transporting ATPase activity
BFW97_03105	COG4695	Portal protein
BFW97_03190	COG2932	Transcriptional regulator
BFW97_03200	COG4974	Belongs to the 'phage' integrase family
BFW97_03205	COG0582	viral genome integration into host DNA
BFW97_03220	COG3561	AntA/AntB antirepressor
BFW97_03245	COG0004	ammonium transporteR
BFW97_03250	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
BFW97_03260	COG0084	hydrolase, TatD family'
BFW97_03265	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BFW97_03275	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
BFW97_03280	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
BFW97_03285	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
BFW97_03290	COG0813	purine-nucleoside phosphorylase activity
BFW97_03295	COG5001	Diguanylate cyclase
BFW97_03295	COG3447	MASE1 domain protein
BFW97_03295	COG5002	protein histidine kinase activity
BFW97_03305	COG0560	Phosphoserine phosphatase
BFW97_03330	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
BFW97_03335	COG0776	regulation of translation
BFW97_03345	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
BFW97_03375	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
BFW97_03380	COG0513	Belongs to the DEAD box helicase family
BFW97_03385	COG3022	response to hydroperoxide
BFW97_03400	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
BFW97_03405	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
BFW97_03410	COG0762	integral membrane protein
BFW97_03415	COG1872	DUF167
BFW97_03430	COG4166	transmembrane transport
BFW97_03440	COG0110	maltose O-acetyltransferase activity
BFW97_03450	COG1024	Enoyl-CoA hydratase
BFW97_03465	COG4221	oxidoreductase activity
BFW97_03470	COG0442	prolyl-tRNA aminoacylation
BFW97_03475	COG0840	transmembrane signaling receptor activity
BFW97_03480	COG0632	four-way junction helicase activity
BFW97_03485	COG2255	four-way junction helicase activity
BFW97_03490	COG1271	oxidase subunit
BFW97_03495	COG1294	oxidase, subunit
BFW97_03500	COG4890	Cyd operon protein YbgT
BFW97_03505	COG3790	cyd operon protein YbgE
BFW97_03510	COG0824	Thioesterase
BFW97_03515	COG0811	peptide transport
BFW97_03530	COG0823	Involved in the tonB-independent uptake of proteins
BFW97_03535	COG2885	chlorophyll binding
BFW97_03540	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
BFW97_03615	COG0840	transmembrane signaling receptor activity
BFW97_03620	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
BFW97_03625	COG0676	glucose-6-phosphate 1-epimerase activity
BFW97_03630	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
BFW97_03635	COG1640	4-alpha-glucanotransferase
BFW97_03640	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
BFW97_03660	COG1051	belongs to the nudix hydrolase family
BFW97_03665	COG2130	NADP-dependent
BFW97_03670	COG1764	response to oxidative stress
BFW97_03675	COG1846	Transcriptional regulator
BFW97_03690	COG1522	sequence-specific DNA binding
BFW97_03705	COG0561	phosphatase activity
BFW97_03720	COG0733	neurotransmitter:sodium symporter activity
BFW97_03730	COG0733	neurotransmitter:sodium symporter activity
BFW97_03755	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BFW97_03770	COG1794	racemase activity, acting on amino acids and derivatives
BFW97_03785	COG2731	YhcH YjgK YiaL family protein
BFW97_03795	COG0668	transmembrane transport
BFW97_03805	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BFW97_03840	COG0583	DNA-binding transcription factor activity
BFW97_03845	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
BFW97_03855	COG0488	(ABC) transporter
BFW97_03860	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
BFW97_03860	COG0517	IMP dehydrogenase activity
BFW97_03865	COG1585	Membrane protein implicated in regulation of membrane protease activity
BFW97_03870	COG0330	HflC and HflK could
BFW97_03875	COG1648	precorrin-2 dehydrogenase activity
BFW97_03875	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
BFW97_03880	COG0175	sulfate reduction
BFW97_03885	COG2895	sulfate adenylyltransferase (ATP) activity
BFW97_03890	COG0471	metal ion transport
BFW97_03890	COG3273	potassium ion transport
BFW97_03895	COG0529	Catalyzes the synthesis of activated sulfate
BFW97_03915	COG0840	transmembrane signaling receptor activity
BFW97_03950	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
BFW97_03965	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
BFW97_03970	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
BFW97_03975	COG0163	prenyltransferase activity
BFW97_03990	COG1131	(ABC) transporter
BFW97_03995	COG0842	Transport permease protein
BFW97_04000	COG1775	2-hydroxyglutaryl-CoA dehydratase, D-component
BFW97_04005	COG1924	4 iron, 4 sulfur cluster binding
BFW97_04025	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
BFW97_04030	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
BFW97_04045	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
BFW97_04050	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
BFW97_04055	COG1489	DNA binding
BFW97_04065	COG1643	Atp-dependent helicase
BFW97_04070	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BFW97_04075	COG0346	lactoylglutathione lyase activity
BFW97_04085	COG2076	Multidrug Resistance protein
BFW97_04095	COG3437	response regulator, receiver
BFW97_04095	COG0784	Response regulator, receiver
BFW97_04105	COG0671	phosphoesterase, PA-phosphatase related
BFW97_04120	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
BFW97_04125	COG0038	chloride channel
BFW97_04135	COG0316	Belongs to the HesB IscA family
BFW97_04160	COG1280	lysine exporter protein (LysE YggA)
BFW97_04165	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
BFW97_04180	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BFW97_04210	COG0745	RESPONSE REGULATOR receiver
BFW97_04215	COG3104	oligopeptide transport
BFW97_04220	COG1210	Utp--glucose-1-phosphate uridylyltransferase
BFW97_04225	COG1555	photosystem II stabilization
BFW97_04235	COG2350	Protein conserved in bacteria
BFW97_04240	COG2917	probably involved in intracellular septation
BFW97_04245	COG0076	glutamate decarboxylase activity
BFW97_04250	COG1272	protein, Hemolysin III
BFW97_04255	COG2985	domain, Protein
BFW97_04255	COG0569	domain protein
BFW97_04270	COG0784	Response regulator, receiver
BFW97_04270	COG0835	chemotaxis
BFW97_04275	COG2755	lipolytic protein G-D-S-L family
BFW97_04280	COG4181	ATPase activity
BFW97_04285	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
BFW97_04290	COG1090	epimerase
BFW97_04295	COG2200	EAL domain
BFW97_04300	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BFW97_04305	COG4935	Belongs to the peptidase S8 family
BFW97_04305	COG2234	aminopeptidase activity
BFW97_04310	COG0220	tRNA (guanine-N7-)-methyltransferase activity
BFW97_04315	COG3171	Protein conserved in bacteria
BFW97_04320	COG2066	Belongs to the glutaminase family
BFW97_04325	COG2897	thiosulfate sulfurtransferase activity
BFW97_04330	COG1404	Belongs to the peptidase S8 family
BFW97_04340	COG1132	(ABC) transporter
BFW97_04360	COG4412	M6 family metalloprotease domain protein
BFW97_04360	COG3291	Pkd domain containing protein
BFW97_04365	COG3076	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome
BFW97_04370	COG5001	Diguanylate cyclase
BFW97_04370	COG3300	MHYT domain
BFW97_04390	COG4628	conserved protein (DUF2132)
BFW97_04395	COG0688	phosphatidylethanolamine metabolic process
BFW97_04400	COG1162	GTPase activity
BFW97_04405	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
BFW97_04445	COG1278	Cold shock
BFW97_04455	COG0840	transmembrane signaling receptor activity
BFW97_04460	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
BFW97_04465	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
BFW97_04470	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
BFW97_04515	COG0848	biopolymer transport protein
BFW97_04520	COG0811	peptide transport
BFW97_04525	COG0811	peptide transport
BFW97_04540	COG4174	ABC transporter (Permease)
BFW97_04545	COG4239	(ABC) transporter, permease
BFW97_04555	COG0444	Belongs to the ABC transporter superfamily
BFW97_04560	COG4608	Belongs to the ABC transporter superfamily
BFW97_04565	COG2195	Cleaves the N-terminal amino acid of tripeptides
BFW97_04570	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
BFW97_04590	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
BFW97_04615	COG0243	molybdopterin cofactor binding
BFW97_04630	COG1116	anion transmembrane transporter activity
BFW97_04630	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BFW97_04635	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BFW97_04640	COG1116	anion transmembrane transporter activity
BFW97_04645	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BFW97_04645	COG2146	nitrite reductase [NAD(P)H] activity
BFW97_04650	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BFW97_04650	COG2146	nitrite reductase [NAD(P)H] activity
BFW97_04655	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BFW97_04660	COG2313	pseudouridylate synthase activity
BFW97_04670	COG1858	cytochrome C peroxidase
BFW97_04705	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BFW97_04710	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BFW97_04735	COG2986	histidine ammonia-lyase
BFW97_04760	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
BFW97_04770	COG1028	Short-chain dehydrogenase reductase Sdr
BFW97_04785	COG0521	Mo-molybdopterin cofactor biosynthetic process
BFW97_04795	COG2966	Psort location CytoplasmicMembrane, score
BFW97_04800	COG3610	response to peptide
BFW97_04810	COG4175	Glycine betaine
BFW97_04815	COG4176	ABC-type proline glycine betaine transport system permease component
BFW97_04820	COG2113	Glycine betaine
BFW97_04825	COG0175	sulfate reduction
BFW97_04830	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BFW97_04835	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
BFW97_04840	COG0384	phenazine biosynthesis protein PhzF
BFW97_04845	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
BFW97_04850	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
BFW97_04860	COG0786	glutamate:sodium symporter activity
BFW97_04865	COG0252	asparaginase activity
BFW97_04870	COG3139	Protein of unknown function (DUF1315)
BFW97_04890	COG0616	signal peptide processing
BFW97_04895	COG1902	pentaerythritol trinitrate reductase activity
BFW97_04895	COG0446	pyridine nucleotide-disulphide oxidoreductase
BFW97_04900	COG0778	Nitroreductase
BFW97_04915	COG2264	protein methyltransferase activity
BFW97_04920	COG0604	alcohol dehydrogenase
BFW97_04925	COG0583	DNA-binding transcription factor activity
BFW97_04930	COG2190	(PTS) system
BFW97_04930	COG1263	PTS System
BFW97_04930	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BFW97_04935	COG4145	pantothenate transmembrane transporter activity
BFW97_04945	COG0439	Biotin carboxylase
BFW97_04950	COG0511	ligase activity, forming carbon-carbon bonds
BFW97_04955	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
BFW97_04960	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BFW97_04970	COG3300	MHYT domain
BFW97_04970	COG5001	Diguanylate cyclase
BFW97_04990	COG3381	protein complex oligomerization
BFW97_05005	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
BFW97_05020	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
BFW97_05025	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BFW97_05025	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BFW97_05045	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
BFW97_05050	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
BFW97_05055	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
BFW97_05060	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
BFW97_05085	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
BFW97_05090	COG0142	geranyltranstransferase activity
BFW97_05095	COG1722	exodeoxyribonuclease VII activity
BFW97_05100	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
BFW97_05105	COG1360	Flagellar Motor Protein
BFW97_05110	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
BFW97_05120	COG1534	Rna-binding protein
BFW97_05125	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
BFW97_05130	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
BFW97_05135	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
BFW97_05140	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
BFW97_05145	COG0149	triose-phosphate isomerase activity
BFW97_05150	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
BFW97_05165	COG0779	Required for maturation of 30S ribosomal subunits
BFW97_05170	COG0195	Participates in both transcription termination and antitermination
BFW97_05175	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
BFW97_05180	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
BFW97_05185	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
BFW97_05190	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
BFW97_05195	COG1185	polyribonucleotide nucleotidyltransferase activity
BFW97_05210	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
BFW97_05220	COG0114	fumarate hydratase activity
BFW97_05230	COG1966	Carbon starvation protein
BFW97_05235	COG3279	Response regulator of the LytR AlgR family
BFW97_05305	COG0312	modulator of DNA gyrase
BFW97_05310	COG0312	modulator of DNA gyrase
BFW97_05315	COG0716	FMN binding
BFW97_05320	COG4974	Belongs to the 'phage' integrase family
BFW97_05325	COG1970	mechanosensitive ion channel activity
BFW97_05330	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
BFW97_05340	COG0789	Transcriptional regulator
BFW97_05355	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
BFW97_05360	COG3545	Serine hydrolase
BFW97_05370	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
BFW97_05375	COG0321	lipoyl(octanoyl) transferase activity
BFW97_05380	COG2921	Belongs to the UPF0250 family
BFW97_05385	COG1686	Belongs to the peptidase S11 family
BFW97_05390	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
BFW97_05395	COG2951	lytic endotransglycosylase activity
BFW97_05400	COG0772	Belongs to the SEDS family
BFW97_05405	COG0768	penicillin binding
BFW97_05410	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
BFW97_05415	COG0799	negative regulation of ribosome biogenesis
BFW97_05420	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
BFW97_05435	COG0495	leucyl-tRNA aminoacylation
BFW97_05440	COG2888	peptidyl-tyrosine sulfation
BFW97_05445	COG0815	Transfers the fatty acyl group on membrane lipoproteins
BFW97_05450	COG4535	Mg2 and Co2 transporter CorC
BFW97_05455	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
BFW97_05460	COG1702	phosphate starvation-inducible protein PhoH
BFW97_05465	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
BFW97_05470	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BFW97_05475	COG1335	isochorismatase
BFW97_05485	COG3706	GGDEF domain
BFW97_05500	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BFW97_05510	COG3706	GGDEF domain
BFW97_05520	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BFW97_05530	COG3647	Membrane
BFW97_05535	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
BFW97_05545	COG0516	GMP reductase activity
BFW97_05555	COG0642	Histidine kinase
BFW97_05560	COG0745	RESPONSE REGULATOR receiver
BFW97_05595	COG3214	Protein conserved in bacteria
BFW97_05620	COG3029	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
BFW97_05625	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
BFW97_05630	COG1053	succinate dehydrogenase
BFW97_05640	COG0584	glycerophosphoryl diester phosphodiesterase
BFW97_05645	COG3264	Mechanosensitive ion channel
BFW97_05645	COG1511	domain protein
BFW97_05655	COG0739	heme binding
BFW97_05670	COG0583	DNA-binding transcription factor activity
BFW97_05690	COG0583	DNA-binding transcription factor activity
BFW97_05695	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
BFW97_05725	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
BFW97_05730	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
BFW97_05740	COG0338	D12 class N6 adenine-specific DNA methyltransferase
BFW97_05745	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
BFW97_05755	COG0180	Tryptophanyl-tRNA synthetase
BFW97_05770	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
BFW97_05780	COG1012	belongs to the aldehyde dehydrogenase family
BFW97_05790	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BFW97_05800	COG0674	pyruvate-flavodoxin oxidoreductase activity
BFW97_05800	COG1013	pyruvate-flavodoxin oxidoreductase activity
BFW97_05800	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
BFW97_05800	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BFW97_05810	COG0366	Alpha amylase catalytic
BFW97_05830	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
BFW97_05840	COG0490	domain, Protein
BFW97_05840	COG0471	metal ion transport
BFW97_05885	COG0012	GTP binding
BFW97_05895	COG0737	Belongs to the 5'-nucleotidase family
BFW97_05900	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
BFW97_05915	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
BFW97_05920	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
BFW97_05925	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
BFW97_05930	COG2890	protein-(glutamine-N5) methyltransferase activity
BFW97_05940	COG2912	Transglutaminase-like superfamily
BFW97_05945	COG2877	3-deoxy-8-phosphooctulonate synthase activity
BFW97_05950	COG1301	dicarboxylic acid transport
BFW97_05960	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
BFW97_05975	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
BFW97_05980	COG1115	amino acid carrier protein
BFW97_05995	COG0714	Associated with various cellular activities
BFW97_06005	COG3104	oligopeptide transport
BFW97_06010	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
BFW97_06015	COG1678	Uncharacterized ACR, COG1678
BFW97_06025	COG0189	ligase activity
BFW97_06030	COG1385	rRNA (uridine-N3-)-methyltransferase activity
BFW97_06040	COG3091	SprT-like family
BFW97_06050	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
BFW97_06060	COG2200	EAL domain
BFW97_06085	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
BFW97_06090	COG0739	heme binding
BFW97_06095	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
BFW97_06100	COG3408	Glycogen debranching enzyme
BFW97_06100	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
BFW97_06110	COG1881	PFAM PEBP family protein
BFW97_06120	COG0583	DNA-binding transcription factor activity
BFW97_06130	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
BFW97_06140	COG0583	DNA-binding transcription factor activity
BFW97_06145	COG1028	Short-chain dehydrogenase reductase Sdr
BFW97_06150	COG0616	signal peptide processing
BFW97_06155	COG3724	N-succinylarginine dihydrolase activity
BFW97_06160	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
BFW97_06175	COG0840	transmembrane signaling receptor activity
BFW97_06185	COG2971	BadF BadG BcrA BcrD
BFW97_06195	COG4608	Belongs to the ABC transporter superfamily
BFW97_06200	COG0444	Belongs to the ABC transporter superfamily
BFW97_06205	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BFW97_06210	COG0601	transmembrane transport
BFW97_06215	COG4166	transmembrane transport
BFW97_06250	COG3220	belongs to the UPF0276 family
BFW97_06280	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
BFW97_06285	COG1289	transmembrane transporter activity
BFW97_06290	COG0303	'Molybdopterin
BFW97_06295	COG0746	molybdenum cofactor guanylyltransferase activity
BFW97_06305	COG4662	Binding-protein-dependent transport system inner membrane component
BFW97_06315	COG2204	response regulator
BFW97_06320	COG3852	Histidine kinase
BFW97_06325	COG1910	domain protein
BFW97_06330	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
BFW97_06365	COG3383	formate dehydrogenase (NAD+) activity
BFW97_06365	COG3383	formate dehydrogenase (NAD+) activity
BFW97_06370	COG0437	4 iron, 4 sulfur cluster binding
BFW97_06385	COG0281	malic enzyme
BFW97_06405	COG2706	6-phosphogluconolactonase activity
BFW97_06415	COG1196	nuclear chromosome segregation
BFW97_06415	COG3264	Mechanosensitive ion channel
BFW97_06420	COG0469	pyruvate kinase activity
BFW97_06435	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
BFW97_06435	COG4651	solute:proton antiporter activity
BFW97_06445	COG2974	May be involved in recombination
BFW97_06455	COG0420	3'-5' exonuclease activity
BFW97_06460	COG0419	ATPase involved in DNA repair
BFW97_06475	COG3038	cytochrome b561
BFW97_06490	COG2190	(PTS) system
BFW97_06500	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
BFW97_06505	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
BFW97_06510	COG0542	response to heat
BFW97_06525	COG1720	tRNA m6t6A37 methyltransferase activity
BFW97_06545	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
BFW97_06550	COG4988	ABC transporter
BFW97_06565	COG0745	RESPONSE REGULATOR receiver
BFW97_06575	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
BFW97_06590	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
BFW97_06595	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
BFW97_06605	COG0083	homoserine kinase activity
BFW97_06610	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
BFW97_06615	COG4319	ketosteroid isomerase
BFW97_06630	COG0488	(ABC) transporter
BFW97_06640	COG0813	purine-nucleoside phosphorylase activity
BFW97_06655	COG2205	protein histidine kinase activity
BFW97_06655	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BFW97_06660	COG3384	dioxygenase
BFW97_06670	COG1283	sodium-dependent phosphate transmembrane transporter activity
BFW97_06680	COG0531	amino acid
BFW97_06690	COG0531	amino acid
BFW97_06705	COG1917	Cupin 2, conserved barrel domain protein
BFW97_06705	COG1396	sequence-specific DNA binding
BFW97_06710	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BFW97_06730	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
BFW97_06740	COG2375	cellular response to nickel ion
BFW97_06745	COG1538	Outer membrane efflux protein
BFW97_06750	COG0577	efflux transmembrane transporter activity
BFW97_06750	COG1136	(ABC) transporter
BFW97_06755	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BFW97_06765	COG1227	inorganic diphosphatase activity
BFW97_06775	COG0497	DNA recombination
BFW97_06780	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
BFW97_06785	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
BFW97_06790	COG0443	Heat shock 70 kDa protein
BFW97_06795	COG0484	heat shock protein binding
BFW97_06825	COG1285	pathogenesis
BFW97_06840	COG0640	Transcriptional regulator
BFW97_06870	COG0095	Lipoate-protein ligase
BFW97_06890	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BFW97_06895	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BFW97_06915	COG0708	Exodeoxyribonuclease III
BFW97_06930	COG2211	Major facilitator Superfamily
BFW97_06975	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
BFW97_06980	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
BFW97_06985	COG1845	cytochrome c oxidase, subunit III
BFW97_06990	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
BFW97_06995	COG0109	protoheme IX farnesyltransferase activity
BFW97_07000	COG2814	Major facilitator Superfamily
BFW97_07010	COG2205	protein histidine kinase activity
BFW97_07010	COG2198	Histidine kinase
BFW97_07010	COG0784	Response regulator, receiver
BFW97_07015	COG1879	ABC-type sugar transport system periplasmic component
BFW97_07025	COG0745	RESPONSE REGULATOR receiver
BFW97_07030	COG3005	denitrification pathway
BFW97_07040	COG3381	protein complex oligomerization
BFW97_07080	COG2003	Belongs to the UPF0758 family
BFW97_07120	COG0583	DNA-binding transcription factor activity
BFW97_07135	COG0549	Belongs to the carbamate kinase family
BFW97_07140	COG1304	FMN binding
BFW97_07145	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
BFW97_07150	COG1335	isochorismatase
BFW97_07165	COG3311	Transcriptional regulator
BFW97_07185	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BFW97_07215	COG0159	tryptophan synthase activity
BFW97_07220	COG0133	tryptophan synthase activity
BFW97_07225	COG0135	phosphoribosylanthranilate isomerase activity
BFW97_07225	COG0134	indole-3-glycerol-phosphate synthase activity
BFW97_07230	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
BFW97_07235	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
BFW97_07235	COG0512	Glutamine amidotransferase of anthranilate synthase
BFW97_07240	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
BFW97_07250	COG0009	L-threonylcarbamoyladenylate synthase
BFW97_07260	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
BFW97_07270	COG1946	Acyl-CoA thioesterase
BFW97_07285	COG1309	transcriptional regulator
BFW97_07290	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BFW97_07295	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BFW97_07315	COG2244	polysaccharide biosynthetic process
BFW97_07325	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
BFW97_07330	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BFW97_07335	COG0662	Cupin 2, conserved barrel domain protein
BFW97_07335	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
BFW97_07345	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
BFW97_07350	COG1091	dTDP-4-dehydrorhamnose reductase activity
BFW97_07355	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
BFW97_07365	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
BFW97_07385	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BFW97_07395	COG3132	Protein of unknown function, DUF480
BFW97_07435	COG1278	Cold shock
BFW97_07465	COG0697	spore germination
BFW97_07470	COG1349	DNA-binding transcription factor activity
BFW97_07480	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
BFW97_07485	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
BFW97_07500	COG1187	pseudouridine synthase activity
BFW97_07515	COG0622	Phosphoesterase
BFW97_07530	COG1261	Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly
BFW97_07535	COG0784	Response regulator, receiver
BFW97_07535	COG0835	chemotaxis
BFW97_07540	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
BFW97_07545	COG1815	bacterial-type flagellum-dependent cell motility
BFW97_07550	COG1558	bacterial-type flagellum-dependent cell motility
BFW97_07565	COG4787	bacterial-type flagellum-dependent cell motility
BFW97_07570	COG4786	Flagellar basal body rod
BFW97_07575	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
BFW97_07580	COG1706	bacterial-type flagellum-dependent cell motility
BFW97_07585	COG3951	Flagellar rod assembly protein muramidase FlgJ
BFW97_07585	COG1705	Flagellar rod assembly protein muramidase FlgJ
BFW97_07590	COG1256	bacterial-type flagellum assembly
BFW97_07600	COG2239	Acts as a magnesium transporter
BFW97_07605	COG0248	Ppx GppA phosphatase
BFW97_07610	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
BFW97_07615	COG2716	regulation of RNA biosynthetic process
BFW97_07625	COG2204	response regulator
BFW97_07630	COG3852	Histidine kinase
BFW97_07635	COG2204	response regulator
BFW97_07640	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
BFW97_07645	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
BFW97_07650	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
BFW97_07655	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
BFW97_07675	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
BFW97_07685	COG0590	tRNA wobble adenosine to inosine editing
BFW97_07690	COG0573	inorganic phosphate transmembrane transporter activity
BFW97_07695	COG0581	inorganic phosphate transmembrane transporter activity
BFW97_07705	COG0704	Plays a role in the regulation of phosphate uptake
BFW97_07710	COG1253	flavin adenine dinucleotide binding
BFW97_07725	COG0531	amino acid
BFW97_07740	COG1126	abc transporter atp-binding protein
BFW97_07745	COG0765	amino acid transport
BFW97_07750	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BFW97_07755	COG3706	GGDEF domain
BFW97_07760	COG2271	Major facilitator Superfamily
BFW97_07775	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
BFW97_07805	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
BFW97_07810	COG0477	Major facilitator Superfamily
BFW97_07815	COG0123	including yeast histone deacetylase and acetoin utilization protein
BFW97_07825	COG1199	ATP-dependent helicase activity
BFW97_07830	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
BFW97_07840	COG1448	Aminotransferase
BFW97_07845	COG0433	COG0433 Predicted ATPase
BFW97_07915	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BFW97_07925	COG1522	sequence-specific DNA binding
BFW97_07955	COG2916	Histone family protein nucleoid-structuring protein H-NS
BFW97_07995	COG1663	tetraacyldisaccharide 4'-kinase activity
BFW97_08000	COG2835	tetraacyldisaccharide 4'-kinase activity
BFW97_08005	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
BFW97_08010	COG2197	response regulator
BFW97_08015	COG0322	excinuclease ABC activity
BFW97_08040	COG0582	viral genome integration into host DNA
BFW97_08060	COG4372	Transposase
BFW97_08080	COG3962	Belongs to the TPP enzyme family
BFW97_08085	COG0673	inositol 2-dehydrogenase activity
BFW97_08090	COG1879	ABC-type sugar transport system periplasmic component
BFW97_08100	COG1172	Belongs to the binding-protein-dependent transport system permease family
BFW97_08105	COG0673	inositol 2-dehydrogenase activity
BFW97_08110	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BFW97_08120	COG3718	enzyme involved in inositol metabolism
BFW97_08125	COG3039	Transposase
BFW97_08130	COG2963	transposase activity
BFW97_08135	COG2801	Transposase and inactivated derivatives
BFW97_08200	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
BFW97_08205	COG0437	4 iron, 4 sulfur cluster binding
BFW97_08210	COG3301	Polysulphide reductase, NrfD
BFW97_08215	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
BFW97_08225	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
BFW97_08230	COG0215	cysteine-tRNA ligase activity
BFW97_08245	COG2199	diguanylate cyclase activity
BFW97_08245	COG2203	Gaf domain
BFW97_08275	COG2119	membrane
BFW97_08280	COG0023	Translation Initiation Factor
BFW97_08305	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
BFW97_08320	COG2205	protein histidine kinase activity
BFW97_08320	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BFW97_08330	COG4138	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system
BFW97_08340	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
BFW97_08345	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
BFW97_08350	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
BFW97_08355	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
BFW97_08360	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
BFW97_08370	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
BFW97_08375	COG0505	Belongs to the CarA family
BFW97_08380	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
BFW97_08385	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
BFW97_08415	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BFW97_08420	COG0513	Belongs to the DEAD box helicase family
BFW97_08430	COG4104	PAAR repeat-containing protein
BFW97_08445	COG0789	Transcriptional regulator
BFW97_08460	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BFW97_08465	COG0765	amino acid transport
BFW97_08475	COG0493	'glutamate synthase
BFW97_08480	COG0070	glutamate synthase
BFW97_08480	COG0067	glutamate synthase
BFW97_08480	COG0069	glutamate synthase activity
BFW97_08485	COG1242	4 iron, 4 sulfur cluster binding
BFW97_08555	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
BFW97_08560	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
BFW97_08560	COG0574	Belongs to the PEP-utilizing enzyme family
BFW97_08605	COG1464	Belongs to the NlpA lipoprotein family
BFW97_08610	COG0671	phosphoesterase, PA-phosphatase related
BFW97_08615	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
BFW97_08620	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
BFW97_08630	COG0101	tRNA pseudouridine synthase activity
BFW97_08635	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
BFW97_08640	COG0285	dihydrofolate synthase activity
BFW97_08645	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
BFW97_08650	COG2920	part of a sulfur-relay system
BFW97_08655	COG1289	transmembrane transporter activity
BFW97_08660	COG0670	Belongs to the BI1 family
BFW97_08680	COG2194	sulfuric ester hydrolase activity
BFW97_08690	COG0392	lysyltransferase activity
BFW97_08690	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
BFW97_08700	COG0840	transmembrane signaling receptor activity
BFW97_08705	COG5001	Diguanylate cyclase
BFW97_08710	COG0564	pseudouridine synthase activity
BFW97_08725	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
BFW97_08735	COG0625	glutathione transferase activity
BFW97_08740	COG0625	glutathione transferase activity
BFW97_08750	COG0367	asparagine synthase
BFW97_08760	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
BFW97_08760	COG4651	solute:proton antiporter activity
BFW97_08765	COG0647	UMP catabolic process
BFW97_08770	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
BFW97_08775	COG1902	pentaerythritol trinitrate reductase activity
BFW97_08780	COG1253	flavin adenine dinucleotide binding
BFW97_08790	COG0277	FAD linked oxidase domain protein
BFW97_08790	COG0247	lactate metabolic process
BFW97_08800	COG2050	protein possibly involved in aromatic compounds catabolism
BFW97_08810	COG2056	Na+-H+ antiporter family
BFW97_08815	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
BFW97_08830	COG0346	lactoylglutathione lyase activity
BFW97_08835	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
BFW97_08845	COG4659	FMN binding
BFW97_08850	COG4658	electron transport chain
BFW97_08860	COG2878	Part of a membrane complex involved in electron transport
BFW97_08865	COG4657	Part of a membrane complex involved in electron transport
BFW97_08870	COG0697	spore germination
BFW97_08885	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
BFW97_08890	COG1288	antiporter activity
BFW97_08895	COG0436	Aminotransferase
BFW97_08905	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
BFW97_08910	COG2027	D-alanyl-D-alanine carboxypeptidase
BFW97_08915	COG1061	Type III restriction enzyme res subunit
BFW97_08920	COG1566	PFAM secretion protein HlyD family protein
BFW97_08930	COG1966	Carbon starvation protein
BFW97_08935	COG3279	Response regulator of the LytR AlgR family
BFW97_08940	COG3275	phosphorelay sensor kinase activity
BFW97_08945	COG2199	diguanylate cyclase activity
BFW97_08945	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
BFW97_08950	COG1012	belongs to the aldehyde dehydrogenase family
BFW97_08950	COG1454	alcohol dehydrogenase
BFW97_08960	COG2095	MarC family integral membrane protein
BFW97_08970	COG0601	transmembrane transport
BFW97_08975	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BFW97_08980	COG0444	Belongs to the ABC transporter superfamily
BFW97_08995	COG0861	Integral membrane protein TerC family
BFW97_09000	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
BFW97_09010	COG1301	dicarboxylic acid transport
BFW97_09025	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
BFW97_09040	COG0537	adenosine 5'-monophosphoramidase activity
BFW97_09075	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BFW97_09080	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BFW97_09090	COG2354	Protein conserved in bacteria
BFW97_09105	COG2233	PERMEase
BFW97_09115	COG1252	NADH dehydrogenase
BFW97_09135	COG0393	Putative heavy-metal-binding
BFW97_09145	COG1648	precorrin-2 dehydrogenase activity
BFW97_09145	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
BFW97_09150	COG2221	Nitrite and sulphite reductase 4Fe-4S
BFW97_09165	COG4667	esterase of the alpha-beta hydrolase superfamily
BFW97_09170	COG1619	proteins homologs of microcin C7 resistance protein MccF
BFW97_09175	COG1368	sulfuric ester hydrolase activity
BFW97_09185	COG0527	aspartate kinase activity
BFW97_09190	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
BFW97_09190	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
BFW97_09195	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BFW97_09220	COG0596	Alpha beta hydrolase
BFW97_09225	COG0346	lactoylglutathione lyase activity
BFW97_09235	COG0583	DNA-binding transcription factor activity
BFW97_09240	COG1620	l-lactate permease
BFW97_09250	COG1139	Iron-sulfur cluster binding protein
BFW97_09275	COG1136	(ABC) transporter
BFW97_09285	COG2814	Major facilitator Superfamily
BFW97_09305	COG0672	)-iron permease
BFW97_09335	COG0659	secondary active sulfate transmembrane transporter activity
BFW97_09380	COG2963	transposase activity
BFW97_09405	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
BFW97_09410	COG0840	transmembrane signaling receptor activity
BFW97_09420	COG2201	protein-glutamate methylesterase activity
BFW97_09430	COG0835	chemotaxis
BFW97_09435	COG3290	protein histidine kinase activity
BFW97_09435	COG0840	transmembrane signaling receptor activity
BFW97_09440	COG2198	Histidine kinase
BFW97_09440	COG0643	Histidine kinase
BFW97_09450	COG0745	RESPONSE REGULATOR receiver
BFW97_09455	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
BFW97_09460	COG0437	4 iron, 4 sulfur cluster binding
BFW97_09465	COG5557	Pfam Polysulphide reductase, NrfD
BFW97_09470	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
BFW97_09475	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
BFW97_09480	COG1773	rubredoxin
BFW97_09485	COG0747	negative chemotaxis
BFW97_09490	COG0601	transmembrane transport
BFW97_09495	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BFW97_09500	COG0444	Belongs to the ABC transporter superfamily
BFW97_09505	COG3842	ATPase activity
BFW97_09510	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
BFW97_09515	COG0375	protein maturation
BFW97_09520	COG0309	Hydrogenase expression formation protein (HypE)
BFW97_09530	COG0298	carbon dioxide binding
BFW97_09535	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
BFW97_09545	COG1921	L-seryl-tRNASec selenium transferase activity
BFW97_09550	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
BFW97_09560	COG3260	NADH ubiquinone oxidoreductase 20
BFW97_09565	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BFW97_09570	COG3261	NADH dehydrogenase
BFW97_09570	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
BFW97_09575	COG0650	Formate hydrogenlyase subunit 4
BFW97_09580	COG0651	ATP synthesis coupled electron transport
BFW97_09585	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
BFW97_09590	COG3158	transport of potassium into the cell
BFW97_09595	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
BFW97_09600	COG3383	formate dehydrogenase (NAD+) activity
BFW97_09605	COG3383	formate dehydrogenase (NAD+) activity
BFW97_09625	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
BFW97_09630	COG0326	Molecular chaperone. Has ATPase activity
BFW97_09635	COG0563	adenylate kinase activity
BFW97_09640	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
BFW97_09650	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BFW97_09670	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
BFW97_09690	COG1021	2,3-dihydroxybenzoate-AMP ligase
BFW97_09695	COG3433	isochorismatase activity
BFW97_09695	COG1535	isochorismatase
BFW97_09700	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BFW97_09705	COG1028	Short-chain dehydrogenase reductase Sdr
BFW97_09715	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BFW97_09720	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BFW97_09725	COG2977	Belongs to the P-Pant transferase superfamily
BFW97_09730	COG1120	ATPase activity
BFW97_09735	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BFW97_09740	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BFW97_09745	COG4771	TonB-dependent receptor
BFW97_09765	COG0598	Magnesium transport protein CorA
BFW97_09785	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
BFW97_09790	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
BFW97_09795	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
BFW97_09810	COG1570	exodeoxyribonuclease VII activity
BFW97_09815	COG0697	spore germination
BFW97_09835	COG3158	transport of potassium into the cell
BFW97_09840	COG0517	IMP dehydrogenase activity
BFW97_09840	COG0516	GMP reductase activity
BFW97_09845	COG0518	GMP synthase (glutamine-hydrolyzing) activity
BFW97_09845	COG0519	Catalyzes the synthesis of GMP from XMP
BFW97_09850	COG0582	viral genome integration into host DNA
BFW97_09890	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
BFW97_09890	COG2169	Transcriptional regulator
BFW97_09915	COG2062	phosphohistidine phosphatase, SixA
BFW97_09925	COG0697	spore germination
BFW97_09930	COG4166	transmembrane transport
BFW97_09935	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
BFW97_09940	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
BFW97_09950	COG4591	ABC-type transport system involved in lipoprotein release permease component
BFW97_09955	COG1136	(ABC) transporter
BFW97_09960	COG4591	ABC-type transport system involved in lipoprotein release permease component
BFW97_09965	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
BFW97_09975	COG0544	peptidyl-prolyl cis-trans isomerase activity
BFW97_09980	COG0740	serine-type endopeptidase activity
BFW97_09985	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
BFW97_09990	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
BFW97_10000	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BFW97_10005	COG0488	(ABC) transporter
BFW97_10010	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BFW97_10015	COG3162	membrane
BFW97_10030	COG1024	Enoyl-CoA hydratase
BFW97_10065	COG1115	amino acid carrier protein
BFW97_10080	COG1584	GPR1 FUN34 yaaH family protein
BFW97_10115	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
BFW97_10120	COG1960	acyl-CoA dehydrogenase activity
BFW97_10130	COG1960	acyl-CoA dehydrogenase activity
BFW97_10135	COG1024	Enoyl-CoA hydratase
BFW97_10140	COG1024	Enoyl-CoA hydratase
BFW97_10150	COG1028	Short-chain dehydrogenase reductase Sdr
BFW97_10160	COG0730	response to heat
BFW97_10185	COG5001	Diguanylate cyclase
BFW97_10185	COG5002	protein histidine kinase activity
BFW97_10195	COG2003	Belongs to the UPF0758 family
BFW97_10205	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
BFW97_10225	COG1073	alpha beta
BFW97_10230	COG0823	Involved in the tonB-independent uptake of proteins
BFW97_10230	COG1506	peptidase
BFW97_10235	COG0702	epimerase
BFW97_10240	COG0583	DNA-binding transcription factor activity
BFW97_10245	COG0667	Aldo Keto reductase
BFW97_10260	COG3706	GGDEF domain
BFW97_10265	COG0583	DNA-binding transcription factor activity
BFW97_10270	COG2723	6-phospho-beta-galactosidase activity
BFW97_10275	COG5001	Diguanylate cyclase
BFW97_10275	COG3300	MHYT domain
BFW97_10285	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
BFW97_10290	COG1028	Short-chain dehydrogenase reductase Sdr
BFW97_10295	COG0583	DNA-binding transcription factor activity
BFW97_10300	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
BFW97_10305	COG0673	inositol 2-dehydrogenase activity
BFW97_10310	COG0583	DNA-binding transcription factor activity
BFW97_10320	COG1560	Kdo2-lipid A biosynthetic process
BFW97_10325	COG1560	Kdo2-lipid A biosynthetic process
BFW97_10350	COG0417	DNA replication proofreading
BFW97_10380	COG0534	Mate efflux family protein
BFW97_10390	COG0307	riboflavin synthase, alpha
BFW97_10400	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BFW97_10405	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
BFW97_10410	COG0697	spore germination
BFW97_10415	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
BFW97_10455	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BFW97_10465	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
BFW97_10470	COG2894	cell division
BFW97_10475	COG0850	regulation of cytokinetic process
BFW97_10480	COG3100	YcgL domain-containing protein
BFW97_10485	COG2951	lytic endotransglycosylase activity
BFW97_10490	COG1760	l-serine dehydratase
BFW97_10495	COG1760	l-serine dehydratase
BFW97_10500	COG3123	guanosine phosphorylase activity
BFW97_10520	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
BFW97_10540	COG1595	DNA-templated transcription, initiation
BFW97_10570	COG0714	Associated with various cellular activities
BFW97_10575	COG0183	Belongs to the thiolase family
BFW97_10580	COG1250	3-hydroxyacyl-CoA dehydrogenase
BFW97_10580	COG1024	Enoyl-CoA hydratase
BFW97_10590	COG4681	YaeQ
BFW97_10610	COG4388	Caudovirus prohead serine protease
BFW97_10620	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
BFW97_10625	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
BFW97_10630	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BFW97_10640	COG0549	Belongs to the carbamate kinase family
BFW97_10645	COG0697	spore germination
BFW97_10650	COG3608	succinylglutamate desuccinylase aspartoacylase
BFW97_10650	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
BFW97_10655	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
BFW97_10665	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
BFW97_10665	COG0493	'glutamate synthase
BFW97_10670	COG0402	S-adenosylhomocysteine deaminase activity
BFW97_10675	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
BFW97_10680	COG2080	2 iron, 2 sulfur cluster binding
BFW97_10680	COG1529	Aldehyde oxidase and xanthine dehydrogenase
BFW97_10685	COG2233	PERMEase
BFW97_10690	COG0402	S-adenosylhomocysteine deaminase activity
BFW97_10695	COG2252	PERMEase
BFW97_10700	COG1529	Aldehyde oxidase and xanthine dehydrogenase
BFW97_10705	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
BFW97_10710	COG2080	2 iron, 2 sulfur cluster binding
BFW97_10720	COG3134	Outer membrane lipoprotein
BFW97_10730	COG1288	antiporter activity
BFW97_10735	COG0318	PFAM AMP-dependent synthetase and ligase
BFW97_10740	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
BFW97_10740	COG0140	phosphoribosyl-ATP diphosphatase activity
BFW97_10745	COG0107	imidazoleglycerol-phosphate synthase activity
BFW97_10750	COG2205	protein histidine kinase activity
BFW97_10750	COG2198	Histidine kinase
BFW97_10750	COG0784	Response regulator, receiver
BFW97_10760	COG3437	response regulator, receiver
BFW97_10765	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
BFW97_10770	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
BFW97_10775	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
BFW97_10775	COG0131	Imidazoleglycerol-phosphate dehydratase
BFW97_10780	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
BFW97_10785	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
BFW97_10790	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
BFW97_10800	COG1199	ATP-dependent helicase activity
BFW97_10805	COG1214	PFAM Peptidase M22, glycoprotease
BFW97_10815	COG0596	Alpha beta hydrolase
BFW97_10815	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
BFW97_10815	COG2226	methyltransferase
BFW97_10820	COG0318	PFAM AMP-dependent synthetase and ligase
BFW97_10825	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
BFW97_10935	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
BFW97_10945	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
BFW97_10950	COG2832	Protein of unknown function (DUF454)
BFW97_10955	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
BFW97_10965	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
BFW97_10970	COG0582	viral genome integration into host DNA
BFW97_11000	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
BFW97_11090	COG0753	catalase activity
BFW97_11115	COG3646	Phage regulatory protein
BFW97_11115	COG3645	SOS response
BFW97_11140	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
BFW97_11145	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
BFW97_11160	COG2916	Histone family protein nucleoid-structuring protein H-NS
BFW97_11320	COG1643	Atp-dependent helicase
BFW97_11340	COG3437	response regulator, receiver
BFW97_11345	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BFW97_11350	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
BFW97_11355	COG0709	Synthesizes selenophosphate from selenide and ATP
BFW97_11375	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
BFW97_11380	COG0840	transmembrane signaling receptor activity
BFW97_11385	COG1254	Belongs to the acylphosphatase family
BFW97_11390	COG0625	glutathione transferase activity
BFW97_11395	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BFW97_11395	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BFW97_11400	COG0489	protein tyrosine kinase activity
BFW97_11405	COG0572	uridine kinase
BFW97_11410	COG0717	Belongs to the dCTP deaminase family
BFW97_11415	COG0306	phosphate transporter
BFW97_11420	COG1530	ribonuclease E activity
BFW97_11425	COG0564	pseudouridine synthase activity
BFW97_11435	COG0424	maF-like protein
BFW97_11440	COG2814	Major facilitator Superfamily
BFW97_11455	COG1399	metal-binding, possibly nucleic acid-binding protein
BFW97_11460	COG0333	Belongs to the bacterial ribosomal protein bL32 family
BFW97_11465	COG0416	fatty acid biosynthetic process
BFW97_11470	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BFW97_11480	COG1028	Short-chain dehydrogenase reductase Sdr
BFW97_11485	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BFW97_11490	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
BFW97_11495	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BFW97_11500	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
BFW97_11505	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
BFW97_11510	COG0470	DNA polymerase III
BFW97_11515	COG0084	hydrolase, TatD family'
BFW97_11530	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
BFW97_11530	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
BFW97_11535	COG3008	intermembrane lipid transfer
BFW97_11540	COG2995	paraquat-inducible protein a
BFW97_11550	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
BFW97_11555	COG0372	Belongs to the citrate synthase family
BFW97_11600	COG4221	oxidoreductase activity
BFW97_11610	COG3141	response to X-ray
BFW97_11620	COG1067	ATP-dependent peptidase activity
BFW97_11625	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
BFW97_11635	COG0488	(ABC) transporter
BFW97_11645	COG0116	Belongs to the methyltransferase superfamily
BFW97_11645	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
BFW97_11655	COG0167	dihydroorotate dehydrogenase activity
BFW97_11660	COG2902	Dehydrogenase
BFW97_11670	COG0308	aminopeptidase N
BFW97_11680	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
BFW97_11685	COG1956	GAF domain-containing protein
BFW97_11695	COG3278	Belongs to the heme-copper respiratory oxidase family
BFW97_11710	COG2010	Cytochrome c
BFW97_11735	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BFW97_11740	COG0589	response to stress
BFW97_11745	COG0037	tRNA processing
BFW97_11760	COG0625	glutathione transferase activity
BFW97_11765	COG1869	D-ribose catabolic process
BFW97_11770	COG1129	ABC transporter
BFW97_11775	COG1172	Belongs to the binding-protein-dependent transport system permease family
BFW97_11780	COG1879	ABC-type sugar transport system periplasmic component
BFW97_11785	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BFW97_11790	COG1609	Transcriptional regulator
BFW97_11805	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
BFW97_11825	COG0776	regulation of translation
BFW97_11830	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BFW97_11830	COG0072	phenylalanine-tRNA ligase activity
BFW97_11835	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
BFW97_11840	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
BFW97_11845	COG0291	Belongs to the bacterial ribosomal protein bL35 family
BFW97_11850	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
BFW97_11855	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
BFW97_11875	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
BFW97_11885	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BFW97_11890	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BFW97_11895	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
BFW97_11900	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
BFW97_11905	COG3313	Fe-S protein
BFW97_11910	COG2942	2-epimerase
BFW97_11915	COG3716	PTS system mannose fructose sorbose family IID component
BFW97_11920	COG3715	PTS system
BFW97_11925	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
BFW97_11925	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BFW97_11940	COG1609	Transcriptional regulator
BFW97_11945	COG2140	Oxalate decarboxylase
BFW97_11950	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BFW97_11950	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
BFW97_11950	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BFW97_11955	COG1105	Belongs to the carbohydrate kinase PfkB family
BFW97_11960	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
BFW97_11960	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
BFW97_11965	COG1609	Transcriptional regulator
BFW97_11970	COG0814	amino acid
BFW97_11980	COG5654	RES domain protein
BFW97_11985	COG0513	Belongs to the DEAD box helicase family
BFW97_11995	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
BFW97_12000	COG2890	protein-(glutamine-N5) methyltransferase activity
BFW97_12005	COG2840	Smr protein MutS2
BFW97_12015	COG3706	GGDEF domain
BFW97_12020	COG0588	phosphoglycerate mutase activity
BFW97_12045	COG2824	Alkylphosphonate utilization operon protein PhnA
BFW97_12060	COG0384	phenazine biosynthesis protein PhzF
BFW97_12075	COG0242	peptide deformylase activity
BFW97_12095	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
BFW97_12100	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
BFW97_12110	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
BFW97_12115	COG1434	Gram-negative-bacterium-type cell wall biogenesis
BFW97_12125	COG0205	6-phosphofructokinase activity
BFW97_12130	COG1473	amidohydrolase
BFW97_12135	COG1011	Hydrolase
BFW97_12140	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
BFW97_12190	COG3593	DNA synthesis involved in DNA repair
BFW97_12205	COG0583	DNA-binding transcription factor activity
BFW97_12210	COG0730	response to heat
BFW97_12225	COG1181	Belongs to the D-alanine--D-alanine ligase family
BFW97_12235	COG0386	Belongs to the glutathione peroxidase family
BFW97_12240	COG0513	Belongs to the DEAD box helicase family
BFW97_12245	COG0456	acetyltransferase
BFW97_12255	COG1742	UPF0060 membrane protein
BFW97_12285	COG2329	Antibiotic biosynthesis monooxygenase
BFW97_12290	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
BFW97_12310	COG3243	poly(R)-hydroxyalkanoic acid synthase
BFW97_12320	COG2501	S4 domain
BFW97_12330	COG1132	(ABC) transporter
BFW97_12335	COG1132	(ABC) transporter
BFW97_12345	COG3118	belongs to the thioredoxin family
BFW97_12350	COG0471	metal ion transport
BFW97_12355	COG0058	SHG alpha-glucan phosphorylase activity
BFW97_12390	COG0814	amino acid
BFW97_12395	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
BFW97_12400	COG0514	ATP-dependent DNA helicase (RecQ)
BFW97_12405	COG2766	serine protein kinase
BFW97_12415	COG2719	SpoVR family
BFW97_12420	COG2186	Transcriptional regulator
BFW97_12425	COG3067	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
BFW97_12430	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
BFW97_12435	COG0586	Pfam SNARE associated Golgi protein
BFW97_12445	COG0556	nucleotide-excision repair
BFW97_12455	COG2985	domain, Protein
BFW97_12455	COG0569	domain protein
BFW97_12460	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
BFW97_12535	COG2916	Histone family protein nucleoid-structuring protein H-NS
BFW97_12580	COG4565	transcriptional regulatory protein
BFW97_12585	COG3290	protein histidine kinase activity
BFW97_12590	COG1940	carbohydrate kinase activity
BFW97_12590	COG1846	Transcriptional regulator
BFW97_12595	COG0840	transmembrane signaling receptor activity
BFW97_12600	COG3012	SEC-C Motif Domain Protein
BFW97_12605	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
BFW97_12610	COG3075	Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses fumarate or nitrate as electron acceptor
BFW97_12615	COG0247	lactate metabolic process
BFW97_12635	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
BFW97_12640	COG0437	4 iron, 4 sulfur cluster binding
BFW97_12645	COG3301	Polysulphide reductase, NrfD
BFW97_12650	COG1138	Cytochrome C-type biogenesis protein
BFW97_12660	COG3088	subunit of a heme lyase
BFW97_12660	COG4235	cytochrome complex assembly
BFW97_12665	COG1051	belongs to the nudix hydrolase family
BFW97_12675	COG3033	Beta-eliminating lyase
BFW97_12680	COG3046	protein related to deoxyribodipyrimidine photolyase
BFW97_12685	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BFW97_12710	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
BFW97_12715	COG0583	DNA-binding transcription factor activity
BFW97_12725	COG4774	siderophore transport
BFW97_12730	COG4977	sequence-specific DNA binding
BFW97_12740	COG0583	DNA-binding transcription factor activity
BFW97_12745	COG2910	NAD(P)H-binding
BFW97_12755	COG0626	cystathionine gamma-synthase activity
BFW97_12760	COG0612	Peptidase, M16
BFW97_12765	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
BFW97_12770	COG2076	Multidrug Resistance protein
BFW97_12775	COG1944	ATP diphosphatase activity
BFW97_12780	COG2116	formate transmembrane transporter activity
BFW97_12785	COG1882	Formate acetyltransferase
BFW97_12790	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BFW97_12800	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
BFW97_12810	COG1840	ABC-type Fe3 transport system, periplasmic component
BFW97_12815	COG3842	ATPase activity
BFW97_12825	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BFW97_12830	COG2983	Belongs to the UPF0260 family
BFW97_12840	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
BFW97_12845	COG0045	succinate-CoA ligase (ADP-forming) activity
BFW97_12850	COG0508	dehydrogenase complex catalyzes the overall conversion of
BFW97_12855	COG0567	Dehydrogenase, E1 component
BFW97_12865	COG1053	succinate dehydrogenase
BFW97_12870	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
BFW97_12875	COG2009	succinate dehydrogenase
BFW97_12895	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
BFW97_12900	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BFW97_12900	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
BFW97_12910	COG3069	C4-dicarboxylate transmembrane transporter activity
BFW97_12925	COG1451	nucleotide metabolic process
BFW97_12940	COG0254	rRNA binding
BFW97_12945	COG0257	Belongs to the bacterial ribosomal protein bL36 family
BFW97_12955	COG0583	DNA-binding transcription factor activity
BFW97_12965	COG1172	Belongs to the binding-protein-dependent transport system permease family
BFW97_12975	COG1879	ABC-type sugar transport system periplasmic component
BFW97_12980	COG1069	ribulokinase activity
BFW97_12990	COG2160	L-arabinose isomerase activity
BFW97_12995	COG2925	Exonuclease
BFW97_13005	COG3345	alpha-galactosidase
BFW97_13010	COG1380	Effector of murein hydrolase LrgA
BFW97_13015	COG1346	cytolysis
BFW97_13020	COG0295	cytidine deaminase activity
BFW97_13025	COG1022	Amp-dependent synthetase and ligase
BFW97_13040	COG0861	Integral membrane protein TerC family
BFW97_13045	COG2885	chlorophyll binding
BFW97_13050	COG2199	diguanylate cyclase activity
BFW97_13065	COG2154	pterin-4-alpha-carbinolamine dehydratase
BFW97_13070	COG2154	pterin-4-alpha-carbinolamine dehydratase
BFW97_13080	COG3768	UPF0283 membrane protein
BFW97_13085	COG3106	COG3106 Predicted ATPase
BFW97_13100	COG1842	Phage shock protein A
BFW97_13105	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
BFW97_13115	COG4168	peptide transport system, permease
BFW97_13120	COG4171	peptide transport system, permease
BFW97_13130	COG4172	Belongs to the ABC transporter superfamily
BFW97_13140	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
BFW97_13145	COG1286	toxin biosynthetic process
BFW97_13150	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
BFW97_13160	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
BFW97_13165	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
BFW97_13170	COG1674	ftsk spoiiie
BFW97_13170	COG0531	amino acid
BFW97_13180	COG0492	ferredoxin-NADP+ reductase activity
BFW97_13185	COG3706	GGDEF domain
BFW97_13190	COG3134	Outer membrane lipoprotein
BFW97_13195	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
BFW97_13200	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
BFW97_13205	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
BFW97_13210	COG0542	response to heat
BFW97_13215	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
BFW97_13220	COG1278	Cold shock
BFW97_13225	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
BFW97_13255	COG3501	Rhs element vgr protein
BFW97_13360	COG3501	Rhs element vgr protein
BFW97_13390	COG1435	thymidine kinase activity
BFW97_13395	COG1757	Na H antiporter
BFW97_13400	COG2916	Histone family protein nucleoid-structuring protein H-NS
BFW97_13405	COG2096	Adenosyltransferase
BFW97_13410	COG3530	Putative quorum-sensing-regulated virulence factor
BFW97_13415	COG0602	queuosine metabolic process
BFW97_13420	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
BFW97_13440	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
BFW97_13450	COG0776	regulation of translation
BFW97_13455	COG0539	negative regulation of cytoplasmic translation
BFW97_13460	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
BFW97_13465	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
BFW97_13475	COG0583	DNA-binding transcription factor activity
BFW97_13495	COG0778	Nitroreductase
BFW97_13500	COG5001	Diguanylate cyclase
BFW97_13500	COG3300	MHYT domain
BFW97_13510	COG0583	DNA-binding transcription factor activity
BFW97_13515	COG3437	response regulator, receiver
BFW97_13540	COG4989	oxidoreductase activity
BFW97_13545	COG0724	RNA recognition motif
BFW97_13565	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
BFW97_13580	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
BFW97_13585	COG1360	Flagellar Motor Protein
BFW97_13590	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BFW97_13595	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BFW97_13600	COG0649	NAD binding
BFW97_13600	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BFW97_13615	COG1034	ATP synthesis coupled electron transport
BFW97_13620	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
BFW97_13625	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BFW97_13630	COG0839	Belongs to the complex I subunit 6 family
BFW97_13635	COG0713	ATP synthesis coupled electron transport
BFW97_13645	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BFW97_13650	COG1007	ATP synthesis coupled electron transport
BFW97_13660	COG0047	phosphoribosylformylglycinamidine synthase activity
BFW97_13660	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
BFW97_13665	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
BFW97_13670	COG1645	bacterial-type flagellum-dependent swarming motility
BFW97_13675	COG1160	GTP binding
BFW97_13680	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BFW97_13685	COG2976	Protein conserved in bacteria
BFW97_13690	COG0124	histidyl-tRNA synthetase
BFW97_13695	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
BFW97_13710	COG0820	rRNA (adenine-C2-)-methyltransferase activity
BFW97_13715	COG0105	UTP biosynthetic process
BFW97_13720	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
BFW97_13730	COG0633	Ferredoxin
BFW97_13735	COG0443	Heat shock 70 kDa protein
BFW97_13740	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
BFW97_13750	COG0822	iron-sulfur transferase activity
BFW97_13755	COG1104	cysteine desulfurase activity
BFW97_13800	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BFW97_13805	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BFW97_13810	COG1862	Preprotein translocase
BFW97_13815	COG0343	queuine tRNA-ribosyltransferase activity
BFW97_13820	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
BFW97_13825	COG0517	IMP dehydrogenase activity
BFW97_13830	COG0450	alkyl hydroperoxide reductase
BFW97_13835	COG3634	alkyl hydroperoxide reductase activity
BFW97_13840	COG2814	Major facilitator Superfamily
BFW97_13855	COG1393	Belongs to the ArsC family
BFW97_13860	COG0798	PFAM Bile acid sodium symporter
BFW97_13865	COG0640	Transcriptional regulator
BFW97_13870	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
BFW97_13870	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
BFW97_13875	COG0509	glycine decarboxylation via glycine cleavage system
BFW97_13880	COG0404	The glycine cleavage system catalyzes the degradation of glycine
BFW97_13885	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BFW97_13890	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BFW97_13910	COG2814	Major facilitator Superfamily
BFW97_13915	COG0625	glutathione transferase activity
BFW97_13925	COG0483	inositol monophosphate 1-phosphatase activity
BFW97_13945	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
BFW97_13960	COG1086	Polysaccharide biosynthesis protein
BFW97_13980	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
BFW97_13990	COG2089	acid synthase
BFW97_14060	COG0301	tRNA thio-modification
BFW97_14060	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BFW97_14070	COG4953	penicillin-binding protein 1C
BFW97_14075	COG2373	Large extracellular alpha-helical protein
BFW97_14080	COG1473	amidohydrolase
BFW97_14085	COG0628	permease
BFW97_14090	COG1538	Outer membrane efflux protein
BFW97_14095	COG1566	PFAM secretion protein HlyD family protein
BFW97_14110	COG0446	pyridine nucleotide-disulphide oxidoreductase
BFW97_14120	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
BFW97_14135	COG4215	(ABC) transporter
BFW97_14140	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BFW97_14150	COG2431	L-lysine efflux transmembrane transporter activity
BFW97_14155	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
BFW97_14160	COG3124	Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP
BFW97_14175	COG1393	Belongs to the ArsC family
BFW97_14185	COG4783	chaperone-mediated protein folding
BFW97_14190	COG0425	Belongs to the sulfur carrier protein TusA family
BFW97_14215	COG3842	ATPase activity
BFW97_14225	COG1175	transmembrane transport
BFW97_14235	COG3081	Nucleoid-associated protein
BFW97_14240	COG3082	Protein of unknown function (DUF1414)
BFW97_14245	COG3083	sulfuric ester hydrolase activity
BFW97_14250	COG4771	TonB-dependent receptor
BFW97_14255	COG1770	oligopeptidase
BFW97_14275	COG4574	serine-type endopeptidase inhibitor activity
BFW97_14280	COG3085	chromosome segregation
BFW97_14285	COG0583	DNA-binding transcription factor activity
BFW97_14290	COG0287	Prephenate dehydrogenase
BFW97_14290	COG1605	Chorismate mutase
BFW97_14295	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
BFW97_14300	COG0584	glycerophosphoryl diester phosphodiesterase
BFW97_14310	COG1349	DNA-binding transcription factor activity
BFW97_14315	COG2271	Major facilitator Superfamily
BFW97_14320	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
BFW97_14325	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
BFW97_14330	COG0583	DNA-binding transcription factor activity
BFW97_14350	COG0656	L-ascorbic acid biosynthetic process
BFW97_14355	COG2814	Major facilitator Superfamily
BFW97_14365	COG1294	oxidase, subunit
BFW97_14375	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BFW97_14385	COG2979	Protein of unknown function (DUF533)
BFW97_14410	COG2271	Major facilitator Superfamily
BFW97_14415	COG0583	DNA-binding transcription factor activity
BFW97_14425	COG2807	transmembrane transport
BFW97_14430	COG1187	pseudouridine synthase activity
BFW97_14455	COG1061	Type III restriction enzyme res subunit
BFW97_14465	COG2964	Protein conserved in bacteria
BFW97_14470	COG3681	Belongs to the UPF0597 family
BFW97_14480	COG0814	amino acid
BFW97_14500	COG1166	arginine decarboxylase activity
BFW97_14505	COG2195	Cleaves the N-terminal amino acid of tripeptides
BFW97_14535	COG0583	DNA-binding transcription factor activity
BFW97_14545	COG2759	Belongs to the formate--tetrahydrofolate ligase family
BFW97_14550	COG0840	transmembrane signaling receptor activity
BFW97_14555	COG0302	gtp cyclohydrolase
BFW97_14565	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
BFW97_14575	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
BFW97_14590	COG0314	molybdopterin synthase activity
BFW97_14595	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
BFW97_14600	COG0315	cyclic pyranopterin monophosphate synthase activity
BFW97_14605	COG0521	Mo-molybdopterin cofactor biosynthetic process
BFW97_14610	COG3005	denitrification pathway
BFW97_14620	COG0348	domain, Protein
BFW97_14625	COG0437	4 iron, 4 sulfur cluster binding
BFW97_14630	COG0243	molybdopterin cofactor binding
BFW97_14640	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
BFW97_14640	COG1149	4fe-4S ferredoxin, iron-sulfur binding domain protein
BFW97_14645	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
BFW97_14650	COG3850	Histidine kinase
BFW97_14655	COG2197	response regulator
BFW97_14685	COG0121	glutamine amidotransferase
BFW97_14690	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
BFW97_14695	COG1960	acyl-CoA dehydrogenase activity
BFW97_14700	COG0784	Response regulator, receiver
BFW97_14700	COG3437	response regulator, receiver
BFW97_14710	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
BFW97_14715	COG0328	RNA-DNA hybrid ribonuclease activity
BFW97_14720	COG2226	methyltransferase
BFW97_14725	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BFW97_14730	COG0741	lytic transglycosylase activity
BFW97_14730	COG1388	LysM domain
BFW97_14735	COG3021	interspecies interaction between organisms
BFW97_14745	COG1607	acyl-coa hydrolase
BFW97_14760	COG0741	lytic transglycosylase activity
BFW97_14770	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
BFW97_14795	COG0729	surface antigen
BFW97_14805	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BFW97_14810	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BFW97_14820	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
BFW97_14830	COG4134	Bacterial extracellular solute-binding protein
BFW97_14840	COG4136	ATPase activity
BFW97_14845	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
BFW97_14850	COG2951	lytic endotransglycosylase activity
BFW97_14855	COG1846	Transcriptional regulator
BFW97_14865	COG0033	Phosphoglucomutase
BFW97_14870	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
BFW97_14875	COG0596	Alpha beta hydrolase
BFW97_14890	COG0716	FMN binding
BFW97_14900	COG0735	belongs to the Fur family
BFW97_14905	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
BFW97_14915	COG2190	(PTS) system
BFW97_14915	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BFW97_14915	COG1263	PTS System
BFW97_14920	COG0363	glucosamine-6-phosphate deaminase activity
BFW97_14925	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
BFW97_14930	COG1940	carbohydrate kinase activity
BFW97_14930	COG1846	Transcriptional regulator
BFW97_14935	COG2194	sulfuric ester hydrolase activity
BFW97_14940	COG0217	transcriptional regulatory protein
BFW97_14945	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
BFW97_14950	COG1801	Protein of unknown function DUF72
BFW97_14955	COG4106	trans-aconitate 2-methyltransferase activity
BFW97_14960	COG0500	methyltransferase
BFW97_14980	COG0450	alkyl hydroperoxide reductase
BFW97_14985	COG0583	DNA-binding transcription factor activity
BFW97_14995	COG0791	NLP P60 protein
BFW97_15010	COG1309	transcriptional regulator
BFW97_15050	COG0534	Mate efflux family protein
BFW97_15070	COG2366	antibiotic biosynthetic process
BFW97_15075	COG1013	pyruvate-flavodoxin oxidoreductase activity
BFW97_15075	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
BFW97_15075	COG0674	pyruvate-flavodoxin oxidoreductase activity
BFW97_15075	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
BFW97_15085	COG0633	Ferredoxin
BFW97_15085	COG3217	Mosc domain protein beta barrel domain protein
BFW97_15085	COG0633	Ferredoxin
BFW97_15085	COG3217	Mosc domain protein beta barrel domain protein
BFW97_15095	COG0501	Belongs to the peptidase M48B family
BFW97_15100	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
BFW97_15105	COG1073	alpha beta
BFW97_15105	COG2226	methyltransferase
BFW97_15110	COG0156	8-amino-7-oxononanoate synthase activity
BFW97_15115	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
BFW97_15135	COG0017	Asparaginyl-tRNA synthetase
BFW97_15140	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
BFW97_15155	COG3069	C4-dicarboxylate transmembrane transporter activity
BFW97_15165	COG0583	DNA-binding transcription factor activity
BFW97_15170	COG1393	Belongs to the ArsC family
BFW97_15175	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BFW97_15180	COG1876	peptidase activity
BFW97_15185	COG3263	regulation of cellular component size
BFW97_15205	COG1280	lysine exporter protein (LysE YggA)
BFW97_15230	COG1957	nucleoside hydrolase
BFW97_15235	COG0564	pseudouridine synthase activity
BFW97_15245	COG1454	alcohol dehydrogenase
BFW97_15295	COG4964	Belongs to the GSP D family
BFW97_15325	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BFW97_15330	COG0702	epimerase
BFW97_15340	COG2867	negative regulation of translational initiation
BFW97_15345	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
BFW97_15430	COG4397	Mu-like prophage major head subunit gpT
BFW97_15435	COG4388	Caudovirus prohead serine protease
BFW97_15455	COG4383	Mu-like prophage protein gp29
BFW97_15460	COG4373	Mu-like prophage FluMu protein gp28
BFW97_15470	COG0640	Transcriptional regulator
BFW97_15505	COG5566	PFAM Mor transcription activator
BFW97_15615	COG0583	DNA-binding transcription factor activity
BFW97_15620	COG2610	gluconate transmembrane transporter activity
BFW97_15625	COG3048	D-serine ammonia-lyase activity
BFW97_15630	COG0538	isocitrate dehydrogenase activity
BFW97_15635	COG2207	Transcriptional regulator
BFW97_15650	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BFW97_15660	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
BFW97_15665	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BFW97_15665	COG1263	PTS System
BFW97_15670	COG1609	Transcriptional regulator
BFW97_15685	COG0456	acetyltransferase
BFW97_15705	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BFW97_15705	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BFW97_15705	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BFW97_15715	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BFW97_15725	COG1187	pseudouridine synthase activity
BFW97_15735	COG0482	sulfurtransferase activity
BFW97_15740	COG2915	High frequency lysogenization protein hflD homolog
BFW97_15745	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
BFW97_15750	COG2850	peptidyl-arginine hydroxylation
BFW97_15760	COG3153	acetyltransferase
BFW97_15770	COG0625	glutathione transferase activity
BFW97_15775	COG0259	pyridoxamine-phosphate oxidase activity
BFW97_15790	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
BFW97_15790	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
BFW97_15795	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
BFW97_15810	COG4235	cytochrome complex assembly
BFW97_15810	COG3088	subunit of a heme lyase
BFW97_15815	COG3088	subunit of a heme lyase
BFW97_15815	COG4235	cytochrome complex assembly
BFW97_15820	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BFW97_15825	COG1138	Cytochrome C-type biogenesis protein
BFW97_15830	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
BFW97_15835	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
BFW97_15840	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
BFW97_15845	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
BFW97_15860	COG0835	chemotaxis
BFW97_15870	COG1192	Involved in chromosome partitioning
BFW97_15875	COG1360	Flagellar Motor Protein
BFW97_15880	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
BFW97_15885	COG2201	protein-glutamate methylesterase activity
BFW97_15890	COG2198	Histidine kinase
BFW97_15890	COG0643	Histidine kinase
BFW97_15895	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
BFW97_15910	COG0455	bacterial-type flagellum organization
BFW97_15920	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
BFW97_15930	COG1684	flagellar biosynthetic protein fliR
BFW97_15935	COG1987	bacterial-type flagellum assembly
BFW97_15985	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
BFW97_15995	COG1677	Flagellar hook-basal body complex protein FliE
BFW97_16010	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
BFW97_16020	COG3064	Membrane
BFW97_16020	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
BFW97_16020	COG1073	alpha beta
BFW97_16035	COG2274	protein secretion by the type I secretion system
BFW97_16045	COG2274	protein secretion by the type I secretion system
BFW97_16050	COG0745	RESPONSE REGULATOR receiver
BFW97_16065	COG1737	Transcriptional regulator
BFW97_16070	COG0469	pyruvate kinase activity
BFW97_16080	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BFW97_16085	COG1960	acyl-CoA dehydrogenase activity
BFW97_16095	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
BFW97_16105	COG0243	molybdopterin cofactor binding
BFW97_16110	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
BFW97_16115	COG0583	DNA-binding transcription factor activity
BFW97_16135	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
BFW97_16140	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
BFW97_16145	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
BFW97_16150	COG1454	alcohol dehydrogenase
BFW97_16150	COG1012	belongs to the aldehyde dehydrogenase family
BFW97_16160	COG1012	belongs to the aldehyde dehydrogenase family
BFW97_16160	COG1454	alcohol dehydrogenase
BFW97_16165	COG1882	Formate acetyltransferase
BFW97_16170	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
BFW97_16175	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
BFW97_16180	COG4869	propanediol catabolic process
BFW97_16230	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BFW97_16240	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
BFW97_16245	COG1737	Transcriptional regulator
BFW97_16250	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BFW97_16255	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
BFW97_16260	COG1349	DNA-binding transcription factor activity
BFW97_16265	COG0738	Major facilitator superfamily
BFW97_16275	COG1070	Carbohydrate kinase
BFW97_16295	COG4172	Belongs to the ABC transporter superfamily
BFW97_16300	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BFW97_16310	COG0747	negative chemotaxis
BFW97_16320	COG1376	ErfK ybiS ycfS ynhG family protein
BFW97_16320	COG1388	LysM domain
BFW97_16335	COG3129	Specifically methylates the adenine in position 1618 of 23S rRNA
BFW97_16340	COG0791	NLP P60 protein
BFW97_16345	COG2091	lysine biosynthetic process via aminoadipic acid
BFW97_16350	COG3118	belongs to the thioredoxin family
BFW97_16360	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
BFW97_16365	COG0788	formyltetrahydrofolate deformylase activity
BFW97_16375	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BFW97_16395	COG0366	Alpha amylase catalytic
BFW97_16400	COG0741	lytic transglycosylase activity
BFW97_16400	COG1196	nuclear chromosome segregation
BFW97_16400	COG0739	heme binding
BFW97_16405	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
BFW97_16410	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
BFW97_16420	COG0673	inositol 2-dehydrogenase activity
BFW97_16440	COG1032	radical SAM domain protein
BFW97_16450	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BFW97_16455	COG1566	PFAM secretion protein HlyD family protein
BFW97_16460	COG2203	Gaf domain
BFW97_16460	COG2199	diguanylate cyclase activity
BFW97_16465	COG1752	Esterase of the alpha-beta hydrolase superfamily
BFW97_16470	COG0733	neurotransmitter:sodium symporter activity
BFW97_16500	COG0281	malic enzyme
BFW97_16510	COG0534	Mate efflux family protein
BFW97_16520	COG0745	RESPONSE REGULATOR receiver
BFW97_16520	COG3706	GGDEF domain
BFW97_16525	COG2233	PERMEase
BFW97_16530	COG0095	Lipoate-protein ligase
BFW97_16535	COG1115	amino acid carrier protein
BFW97_16540	COG0019	diaminopimelate decarboxylase activity
BFW97_16550	COG0678	peroxiredoxin activity
BFW97_16560	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
BFW97_16580	COG1131	(ABC) transporter
BFW97_16585	COG0545	Peptidyl-prolyl cis-trans isomerase
BFW97_16590	COG3142	Participates in the control of copper homeostasis
BFW97_16605	COG4783	chaperone-mediated protein folding
BFW97_16615	COG5002	protein histidine kinase activity
BFW97_16620	COG0745	RESPONSE REGULATOR receiver
BFW97_16625	COG0346	lactoylglutathione lyase activity
BFW97_16630	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BFW97_16635	COG1960	acyl-CoA dehydrogenase activity
BFW97_16640	COG3284	Transcriptional regulator
BFW97_16645	COG1012	belongs to the aldehyde dehydrogenase family
BFW97_16655	COG0697	spore germination
BFW97_16660	COG4565	transcriptional regulatory protein
BFW97_16665	COG3290	protein histidine kinase activity
BFW97_16670	COG0281	malic enzyme
BFW97_16680	COG1846	Transcriptional regulator
BFW97_16685	COG1566	PFAM secretion protein HlyD family protein
BFW97_16715	COG0602	queuosine metabolic process
BFW97_16720	COG1328	CTP reductase activity
BFW97_16730	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
BFW97_16735	COG3115	cell septum assembly
BFW97_16740	COG1196	nuclear chromosome segregation
BFW97_16750	COG2860	membrane
BFW97_16760	COG3108	Peptidase M15
BFW97_16765	COG2989	Protein conserved in bacteria
BFW97_16780	COG0463	Glycosyl transferase, family 2
BFW97_16795	COG0366	Alpha amylase catalytic
BFW97_16830	COG3706	GGDEF domain
BFW97_16840	COG3590	peptidase
BFW97_16850	COG0488	(ABC) transporter
BFW97_16860	COG0531	amino acid
BFW97_16875	COG0814	amino acid
BFW97_16890	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
BFW97_16895	COG1982	Orn Lys Arg decarboxylase major
BFW97_16900	COG0531	amino acid
BFW97_16905	COG3710	Transcriptional regulator
BFW97_16910	COG0825	malonyl-CoA metabolic process
BFW97_16920	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
BFW97_16925	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
BFW97_16930	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
BFW97_16935	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
BFW97_16940	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
BFW97_16955	COG0750	zinc metalloprotease
BFW97_16960	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
BFW97_16965	COG0575	Belongs to the CDS family
BFW97_16975	COG0233	cytoplasmic translational termination
BFW97_16980	COG0528	UMP kinase activity
BFW97_16985	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
BFW97_16990	COG0052	Belongs to the universal ribosomal protein uS2 family
BFW97_16995	COG0024	Methionine aminopeptidase
BFW97_17000	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
BFW97_17005	COG2171	N-acyltransferase activity
BFW97_17015	COG1263	PTS System
BFW97_17015	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BFW97_17025	COG4580	involved in the transport of maltose and maltodextrins
BFW97_17035	COG0564	pseudouridine synthase activity
BFW97_17040	COG3098	single-species biofilm formation
BFW97_17065	COG5595	Zn-ribbon-containing, possibly nucleic-acid-binding protein (DUF2310)
BFW97_17075	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
BFW97_17075	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
BFW97_17085	COG3706	GGDEF domain
BFW97_17090	COG1611	Belongs to the LOG family
BFW97_17095	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BFW97_17100	COG0473	3-isopropylmalate dehydrogenase activity
BFW97_17110	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
BFW97_17115	COG2363	Small membrane protein
BFW97_17125	COG0583	DNA-binding transcription factor activity
BFW97_17130	COG0840	transmembrane signaling receptor activity
BFW97_17135	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
BFW97_17150	COG1477	protein flavinylation
BFW97_17155	COG2871	sodium ion transport
BFW97_17160	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
BFW97_17165	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
BFW97_17170	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
BFW97_17175	COG1805	sodium ion transport
BFW97_17180	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
BFW97_17185	COG0271	Belongs to the BolA IbaG family
BFW97_17190	COG2813	Specifically methylates the guanine in position
BFW97_17200	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
BFW97_17210	COG2211	Major facilitator Superfamily
BFW97_17215	COG3248	Nucleoside-binding outer membrane protein
BFW97_17220	COG1666	GTP binding
BFW97_17225	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
BFW97_17230	COG0693	protein deglycase activity
BFW97_17275	COG2771	luxR family
BFW97_17285	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
BFW97_17285	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
BFW97_17290	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
BFW97_17300	COG1151	hydroxylamine reductase activity
BFW97_17305	COG0783	Belongs to the Dps family
BFW97_17330	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
BFW97_17345	COG4221	oxidoreductase activity
BFW97_17355	COG0415	Belongs to the DNA photolyase family
BFW97_17360	COG0789	Transcriptional regulator
BFW97_17365	COG3272	Protein of unknown function (DUF1722)
BFW97_17395	COG0077	Prephenate dehydratase
BFW97_17395	COG1605	Chorismate mutase
BFW97_17425	COG5377	YqaJ viral recombinase family
BFW97_17465	COG2003	Belongs to the UPF0758 family
BFW97_17475	COG0602	queuosine metabolic process
BFW97_17480	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
BFW97_17495	COG0720	synthase
BFW97_17530	COG0514	ATP-dependent DNA helicase (RecQ)
BFW97_17535	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
BFW97_17560	COG4771	TonB-dependent receptor
BFW97_17620	COG2226	methyltransferase
BFW97_17665	COG2226	methyltransferase
BFW97_17695	COG2133	pyrroloquinoline quinone binding
BFW97_17705	COG0840	transmembrane signaling receptor activity
BFW97_17715	COG0300	oxidoreductase activity
BFW97_17740	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
BFW97_17755	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
BFW97_17760	COG0826	peptidase U32
BFW97_17765	COG1280	lysine exporter protein (LysE YggA)
BFW97_17780	COG0840	transmembrane signaling receptor activity
BFW97_17785	COG0745	RESPONSE REGULATOR receiver
BFW97_17795	COG2198	Histidine kinase
BFW97_17795	COG0643	Histidine kinase
BFW97_17805	COG0835	chemotaxis
BFW97_17810	COG0840	transmembrane signaling receptor activity
BFW97_17820	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
BFW97_17825	COG2201	protein-glutamate methylesterase activity
BFW97_17830	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
BFW97_17860	COG2199	diguanylate cyclase activity
BFW97_17860	COG2203	Gaf domain
BFW97_17860	COG2200	EAL domain
BFW97_17870	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
BFW97_17875	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
BFW97_17880	COG0305	Participates in initiation and elongation during chromosome replication
BFW97_17890	COG2200	EAL domain
BFW97_17895	COG0737	Belongs to the 5'-nucleotidase family
BFW97_17915	COG2204	response regulator
BFW97_17920	COG0545	Peptidyl-prolyl cis-trans isomerase
BFW97_17930	COG2900	Belongs to the SlyX family
BFW97_17935	COG1047	Peptidyl-prolyl cis-trans
BFW97_17940	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
BFW97_17950	COG0784	Response regulator, receiver
BFW97_17950	COG0835	chemotaxis
BFW97_17955	COG0429	hydrolase of the alpha beta-hydrolase fold
BFW97_17960	COG4251	negative regulation of phosphorylation
BFW97_17960	COG2203	Gaf domain
BFW97_17960	COG5001	Diguanylate cyclase
BFW97_17960	COG3706	GGDEF domain
BFW97_17965	COG3089	Belongs to the UPF0270 family
BFW97_17975	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
BFW97_17980	COG0463	Glycosyl transferase, family 2
BFW97_17985	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BFW97_17985	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
BFW97_17990	COG0726	polysaccharide deacetylase
BFW97_17995	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
BFW97_18000	COG2076	Multidrug Resistance protein
BFW97_18005	COG2076	Multidrug Resistance protein
BFW97_18010	COG3954	Phosphoribulokinase
BFW97_18025	COG1765	OsmC-like protein
BFW97_18030	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BFW97_18035	COG2226	methyltransferase
BFW97_18040	COG3397	chitin binding
BFW97_18055	COG2202	Pas domain
BFW97_18055	COG2205	protein histidine kinase activity
BFW97_18065	COG3655	Transcriptional regulator
BFW97_18070	COG2814	Major facilitator Superfamily
BFW97_18075	COG4771	TonB-dependent receptor
BFW97_18095	COG0748	coenzyme F420 binding
BFW97_18100	COG3721	Heme iron utilization protein
BFW97_18110	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BFW97_18135	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
BFW97_18140	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BFW97_18145	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
BFW97_18165	COG0741	lytic transglycosylase activity
BFW97_18170	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
BFW97_18265	COG0616	signal peptide processing
BFW97_18280	COG1802	Transcriptional regulator
BFW97_18280	COG4626	Terminase
BFW97_18320	COG0464	growth
BFW97_18445	COG0582	viral genome integration into host DNA
BFW97_18450	COG0488	(ABC) transporter
BFW97_18460	COG2252	PERMEase
BFW97_18465	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
BFW97_18470	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
BFW97_18480	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
BFW97_18490	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
BFW97_18495	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
BFW97_18505	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
BFW97_18515	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BFW97_18520	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
BFW97_18535	COG0318	PFAM AMP-dependent synthetase and ligase
BFW97_18545	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
BFW97_18550	COG0211	Belongs to the bacterial ribosomal protein bL27 family
BFW97_18560	COG0142	geranyltranstransferase activity
BFW97_18565	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
BFW97_18570	COG0330	HflC and HflK could
BFW97_18575	COG0330	HflC and HflK could
BFW97_18580	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
BFW97_18585	COG1923	regulation of RNA biosynthetic process
BFW97_18590	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
BFW97_18595	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
BFW97_18605	COG0802	atpase or kinase
BFW97_18610	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
BFW97_18610	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
BFW97_18635	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
BFW97_18640	COG2011	ABC-type metal ion transport system permease component
BFW97_18645	COG1464	Belongs to the NlpA lipoprotein family
BFW97_18655	COG0840	transmembrane signaling receptor activity
BFW97_18680	COG2198	Histidine kinase
BFW97_18680	COG0784	Response regulator, receiver
BFW97_18680	COG5002	protein histidine kinase activity
BFW97_18700	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
BFW97_18715	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
BFW97_18720	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
BFW97_18730	COG2716	regulation of RNA biosynthetic process
BFW97_18735	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
BFW97_18740	COG3013	Belongs to the UPF0304 family
BFW97_18745	COG3092	negative regulation of chromosome organization
BFW97_18750	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
BFW97_18755	COG0857	belongs to the CobB CobQ family
BFW97_18755	COG0280	phosphate acetyltransferase
BFW97_18765	COG0028	Belongs to the TPP enzyme family
BFW97_18775	COG0671	phosphoesterase, PA-phosphatase related
BFW97_18785	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
BFW97_18790	COG0473	3-isopropylmalate dehydrogenase activity
BFW97_18795	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
BFW97_18800	COG0066	3-isopropylmalate dehydratase activity
BFW97_18815	COG4143	(ABC) transporter
BFW97_18820	COG1178	ABC-type Fe3 transport system permease component
BFW97_18825	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
BFW97_18830	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
BFW97_18840	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BFW97_18870	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
BFW97_18875	COG0564	pseudouridine synthase activity
BFW97_18885	COG3300	MHYT domain
BFW97_18885	COG5001	Diguanylate cyclase
BFW97_18895	COG0459	protein refolding
BFW97_18900	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
BFW97_18905	COG0534	Mate efflux family protein
BFW97_18910	COG3030	protein affecting phage T7 exclusion by the F plasmid
BFW97_18915	COG1027	Aspartate ammonia-lyase
BFW97_18920	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
BFW97_18930	COG0477	Major facilitator Superfamily
BFW97_18950	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BFW97_18960	COG0673	inositol 2-dehydrogenase activity
BFW97_18970	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
BFW97_18975	COG0635	Involved in the biosynthesis of porphyrin-containing compound
BFW97_18980	COG3036	rescue of stalled ribosome
BFW97_18985	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
BFW97_18995	COG0138	bifunctional purine biosynthesis protein purh
BFW97_19000	COG0151	Belongs to the GarS family
BFW97_19030	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
BFW97_19035	COG0358	DNA primase activity
BFW97_19040	COG1610	YqeY-like protein
BFW97_19045	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
BFW97_19055	COG1388	LysM domain
BFW97_19055	COG4942	peptidase
BFW97_19060	COG1238	metal cluster binding
BFW97_19065	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
BFW97_19070	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
BFW97_19075	COG0585	pseudouridine synthase activity
BFW97_19085	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
BFW97_19090	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
BFW97_19095	COG0148	phosphopyruvate hydratase activity
BFW97_19100	COG0504	CTP synthase activity
BFW97_19105	COG3956	TIGRFAM MazG family protein
BFW97_19110	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
BFW97_19115	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
BFW97_19125	COG4807	Protein conserved in bacteria
BFW97_19130	COG3023	N-Acetylmuramoyl-L-alanine amidase
BFW97_19135	COG1349	DNA-binding transcription factor activity
BFW97_19145	COG2222	sugar isomerase
BFW97_19150	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BFW97_19160	COG3716	PTS system mannose fructose sorbose family IID component
BFW97_19165	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
BFW97_19170	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
BFW97_19185	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
BFW97_19190	COG1381	Involved in DNA repair and RecF pathway recombination
BFW97_19200	COG0571	ribonuclease III activity
BFW97_19205	COG0681	Belongs to the peptidase S26 family
BFW97_19210	COG0481	GTPase activity
BFW97_19225	COG3073	An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E
BFW97_19230	COG1595	DNA-templated transcription, initiation
BFW97_19235	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
BFW97_19245	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
BFW97_19250	COG0354	folic acid binding
BFW97_19285	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BFW97_19290	COG0191	fructose-bisphosphate aldolase activity
BFW97_19295	COG0126	phosphoglycerate kinase activity
BFW97_19300	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
BFW97_19305	COG1940	carbohydrate kinase activity
BFW97_19310	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
BFW97_19325	COG4991	sh3 domain protein
BFW97_19330	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BFW97_19345	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
BFW97_19365	COG1505	serine-type exopeptidase activity
BFW97_19370	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
BFW97_19375	COG0765	amino acid transport
BFW97_19380	COG0765	amino acid transport
BFW97_19385	COG1126	abc transporter atp-binding protein
BFW97_19390	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BFW97_19395	COG1136	(ABC) transporter
BFW97_19395	COG0577	efflux transmembrane transporter activity
BFW97_19400	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BFW97_19405	COG0745	RESPONSE REGULATOR receiver
BFW97_19410	COG2205	protein histidine kinase activity
BFW97_19450	COG2070	2-Nitropropane dioxygenase
BFW97_19475	COG1858	cytochrome C peroxidase
BFW97_19480	COG1912	Pfam S-adenosyl-l-methionine hydroxide adenosyltransferase
BFW97_19500	COG0513	Belongs to the DEAD box helicase family
BFW97_19515	COG0154	amidase activity
BFW97_19520	COG2957	Belongs to the agmatine deiminase family
BFW97_19535	COG1902	pentaerythritol trinitrate reductase activity
BFW97_19565	COG3706	GGDEF domain
BFW97_19565	COG0745	RESPONSE REGULATOR receiver
BFW97_19570	COG5001	Diguanylate cyclase
BFW97_19580	COG0714	Associated with various cellular activities
BFW97_19590	COG0456	acetyltransferase
BFW97_19600	COG1022	Amp-dependent synthetase and ligase
BFW97_19610	COG2918	glutathione biosynthetic process
BFW97_19615	COG0612	Peptidase, M16
BFW97_19620	COG1238	metal cluster binding
BFW97_19640	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
BFW97_19645	COG0359	binds to the 23S rRNA
BFW97_19650	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
BFW97_19655	COG0360	Binds together with S18 to 16S ribosomal RNA
BFW97_19660	COG1914	H( )-stimulated, divalent metal cation uptake system
BFW97_19680	COG2153	protein acetylation
BFW97_19690	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BFW97_19695	COG0557	exoribonuclease II activity
BFW97_19700	COG3706	GGDEF domain
BFW97_19705	COG1854	S-ribosylhomocysteine lyase activity
BFW97_19720	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
BFW97_19720	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BFW97_19780	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
BFW97_19785	COG1047	Peptidyl-prolyl cis-trans
BFW97_19790	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
BFW97_19795	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
BFW97_19800	COG0196	riboflavin kinase activity
BFW97_19805	COG0728	peptidoglycan biosynthetic process
BFW97_19810	COG0268	Binds directly to 16S ribosomal RNA
BFW97_19815	COG0640	Transcriptional regulator
BFW97_19820	COG0583	DNA-binding transcription factor activity
BFW97_19830	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
BFW97_19835	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
BFW97_19840	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
BFW97_19850	COG1051	belongs to the nudix hydrolase family
BFW97_19855	COG3066	DNA modification
BFW97_19865	COG0335	large ribosomal subunit rRNA binding
BFW97_19870	COG0336	Belongs to the RNA methyltransferase TrmD family
BFW97_19875	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
BFW97_19880	COG0228	four-way junction DNA binding
BFW97_19885	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
BFW97_19890	COG4137	Cytochrome C assembly protein
BFW97_19895	COG4536	flavin adenine dinucleotide binding
BFW97_19905	COG1017	nitric oxide dioxygenase activity
BFW97_19905	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
BFW97_19910	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
BFW97_19915	COG0039	L-malate dehydrogenase activity
BFW97_19920	COG4160	amino acid transport
BFW97_19925	COG4215	(ABC) transporter
BFW97_19930	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BFW97_19935	COG1126	abc transporter atp-binding protein
BFW97_19940	COG1438	arginine binding
BFW97_19945	COG2837	iron assimilation
BFW97_19950	COG3842	ATPase activity
BFW97_19960	COG1840	ABC-type Fe3 transport system, periplasmic component
BFW97_19965	COG0347	Belongs to the P(II) protein family
BFW97_19980	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BFW97_19985	COG0583	DNA-binding transcription factor activity
BFW97_20000	COG1929	Belongs to the glycerate kinase type-1 family
BFW97_20005	COG2610	gluconate transmembrane transporter activity
BFW97_20010	COG3835	regulator
BFW97_20015	COG3112	Uncharacterised protein family (UPF0231)
BFW97_20030	COG0840	transmembrane signaling receptor activity
BFW97_20035	COG3568	Endonuclease Exonuclease Phosphatase
BFW97_20050	COG0513	Belongs to the DEAD box helicase family
BFW97_20090	COG1448	Aminotransferase
BFW97_20105	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
BFW97_20110	COG1328	CTP reductase activity
BFW97_20130	COG0793	Belongs to the peptidase S41A family
BFW97_20130	COG4946	Tricorn protease homolog
BFW97_20160	COG0840	transmembrane signaling receptor activity
BFW97_20165	COG3397	chitin binding
BFW97_20170	COG0583	DNA-binding transcription factor activity
BFW97_20175	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
BFW97_20180	COG4208	sulfate ABC transporter
BFW97_20185	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
BFW97_20195	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
BFW97_20200	COG3174	membrane
BFW97_20205	COG0110	maltose O-acetyltransferase activity
BFW97_20230	COG0165	Argininosuccinate lyase
BFW97_20235	COG0137	argininosuccinate synthase activity
BFW97_20245	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
BFW97_20250	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
BFW97_20260	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
BFW97_20270	COG0527	aspartate kinase activity
BFW97_20270	COG0460	homoserine dehydrogenase
BFW97_20275	COG0626	cystathionine gamma-synthase activity
BFW97_20285	COG2207	Transcriptional regulator
BFW97_20285	COG3708	Transcriptional regulator
BFW97_20290	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BFW97_20295	COG0814	amino acid
BFW97_20300	COG1218	3'(2'),5'-bisphosphate nucleotidase
BFW97_20305	COG0494	nUDIX hydrolase
BFW97_20310	COG1011	Hydrolase
BFW97_20315	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
BFW97_20330	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
BFW97_20340	COG3156	type II secretion system protein K
BFW97_20345	COG4795	General secretion pathway protein
BFW97_20350	COG2165	general secretion pathway protein
BFW97_20360	COG2165	general secretion pathway protein
BFW97_20365	COG1459	type II secretion system
BFW97_20370	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
BFW97_20380	COG3031	protein transport across the cell outer membrane
BFW97_20390	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
BFW97_20415	COG0456	acetyltransferase
BFW97_20420	COG3133	Outer membrane lipoprotein
BFW97_20435	COG2771	luxR family
BFW97_20440	COG3916	Acyl-homoserine-lactone synthase
BFW97_20450	COG4776	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction
BFW97_20455	COG1309	transcriptional regulator
BFW97_20465	COG2213	PTS system mannitol-specific
BFW97_20465	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
BFW97_20470	COG0246	Mannitol dehydrogenase
BFW97_20475	COG3722	fumarate hydratase activity
BFW97_20480	COG3263	regulation of cellular component size
BFW97_20505	COG1671	Belongs to the UPF0178 family
BFW97_20520	COG1988	membrane-bound metal-dependent
BFW97_20525	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BFW97_20530	COG0513	Belongs to the DEAD box helicase family
BFW97_20555	COG1575	Belongs to the MenA family. Type 1 subfamily
BFW97_20560	COG1169	isochorismate synthase
BFW97_20565	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
BFW97_20570	COG0596	Alpha beta hydrolase
BFW97_20575	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
BFW97_20580	COG1441	menaquinone biosynthetic process
BFW97_20585	COG0318	PFAM AMP-dependent synthetase and ligase
BFW97_20600	COG3539	Fimbrial protein
BFW97_20605	COG3121	Chaperone
BFW97_20610	COG3188	usher protein
BFW97_20620	COG3539	Fimbrial protein
BFW97_20630	COG3291	Pkd domain containing protein
BFW97_20635	COG2949	membrane
BFW97_20650	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
BFW97_20655	COG5380	lipid catabolic process
BFW97_20670	COG4533	DNA binding
BFW97_20675	COG2873	o-acetylhomoserine
BFW97_20685	COG1979	alcohol dehydrogenase
BFW97_20705	COG4221	oxidoreductase activity
BFW97_20725	COG1285	pathogenesis
BFW97_20745	COG1368	sulfuric ester hydrolase activity
BFW97_20750	COG1522	sequence-specific DNA binding
BFW97_20760	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
BFW97_20765	COG1418	mRNA catabolic process
BFW97_20770	COG1058	Belongs to the CinA family
BFW97_20770	COG1546	Belongs to the CinA family
BFW97_20780	COG0842	Transport permease protein
BFW97_20780	COG1129	ABC transporter
BFW97_20795	COG0561	phosphatase activity
BFW97_20800	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
BFW97_20820	COG1011	Hydrolase
BFW97_20835	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
BFW97_20840	COG0019	diaminopimelate decarboxylase activity
BFW97_20845	COG1965	Belongs to the frataxin family
BFW97_20850	COG0400	carboxylic ester hydrolase activity
BFW97_20855	COG3072	Adenylate cyclase
BFW97_20860	COG0181	hydroxymethylbilane synthase activity
BFW97_20870	COG2959	enzyme of heme biosynthesis
BFW97_20885	COG1494	fructose-1,6-bisphosphatase
BFW97_20925	COG1733	regulation of RNA biosynthetic process
BFW97_20945	COG3932	Exopolysaccharide synthesis, ExoD
BFW97_20950	COG0814	amino acid
BFW97_20955	COG3706	GGDEF domain
BFW97_20970	COG3417	Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1B (PBP1b)
BFW97_20980	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
BFW97_20985	COG2022	thiamine diphosphate biosynthetic process
BFW97_20995	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
BFW97_21000	COG0352	thiamine-phosphate diphosphorylase activity
BFW97_21005	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
BFW97_21025	COG0745	RESPONSE REGULATOR receiver
BFW97_21035	COG1114	Component of the transport system for branched-chain amino acids
BFW97_21040	COG0189	ligase activity
BFW97_21075	COG3171	Protein conserved in bacteria
BFW97_21090	COG3188	usher protein
BFW97_21140	COG1639	'signal transduction protein
BFW97_21150	COG2321	neutral zinc metallopeptidase
BFW97_21155	COG3700	Belongs to the class B bacterial acid phosphatase family
BFW97_21175	COG1366	Belongs to the anti-sigma-factor antagonist family
BFW97_21180	COG2172	sigma factor antagonist activity
BFW97_21185	COG5002	protein histidine kinase activity
BFW97_21185	COG2205	protein histidine kinase activity
BFW97_21185	COG0784	Response regulator, receiver
BFW97_21190	COG3437	response regulator, receiver
BFW97_21200	COG0477	Major facilitator Superfamily
BFW97_21215	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
BFW97_21220	COG1263	PTS System
BFW97_21220	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BFW97_21240	COG0312	modulator of DNA gyrase
BFW97_21245	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BFW97_21255	COG3164	Protein of unknown function
BFW97_21260	COG1530	ribonuclease E activity
BFW97_21265	COG0424	maF-like protein
BFW97_21270	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
BFW97_21275	COG1792	Involved in formation and maintenance of cell shape
BFW97_21280	COG1077	Cell shape determining protein MreB Mrl
BFW97_21305	COG4968	Prepilin-type N-terminal cleavage methylation domain
BFW97_21325	COG1459	type II secretion system
BFW97_21330	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
BFW97_21340	COG2842	Transposition protein
BFW97_21375	COG2200	EAL domain
BFW97_21375	COG2199	diguanylate cyclase activity
BFW97_21380	COG2200	EAL domain
BFW97_21385	COG0387	Pfam Sodium calcium exchanger
BFW97_21390	COG2986	histidine ammonia-lyase
BFW97_21395	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
BFW97_21400	COG0010	Belongs to the arginase family
BFW97_21405	COG1228	amidohydrolase
BFW97_21410	COG2188	Transcriptional regulator
BFW97_21415	COG0288	reversible hydration of carbon dioxide
BFW97_21425	COG2177	Part of the ABC transporter FtsEX involved in
BFW97_21430	COG2884	Cell division ATP-binding protein ftsE
BFW97_21435	COG0552	protein localization to endoplasmic reticulum
BFW97_21440	COG0742	ribosomal rna small subunit methyltransferase
BFW97_21465	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BFW97_21470	COG0741	lytic transglycosylase activity
BFW97_21490	COG2095	MarC family integral membrane protein
BFW97_21500	COG1301	dicarboxylic acid transport
BFW97_21525	COG3714	YhhN family
BFW97_21540	COG1770	oligopeptidase
BFW97_21555	COG4221	oxidoreductase activity
BFW97_21560	COG0583	DNA-binding transcription factor activity
BFW97_21565	COG2249	NAD(P)H dehydrogenase (quinone) activity
BFW97_21610	COG0203	ribosomal protein L17
BFW97_21615	COG0202	RNA polymerase activity
BFW97_21620	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
BFW97_21625	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
BFW97_21630	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
BFW97_21635	COG0201	protein transport
BFW97_21640	COG0200	Binds to the 23S rRNA
BFW97_21645	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
BFW97_21650	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
BFW97_21655	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
BFW97_21660	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
BFW97_21665	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
BFW97_21670	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
BFW97_21675	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
BFW97_21680	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
BFW97_21685	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
BFW97_21690	COG0255	Belongs to the universal ribosomal protein uL29 family
BFW97_21695	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
BFW97_21700	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
BFW97_21705	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
BFW97_21710	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
BFW97_21715	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
BFW97_21720	COG0089	rRNA binding
BFW97_21725	COG0088	Forms part of the polypeptide exit tunnel
BFW97_21730	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
BFW97_21735	COG0051	transcription antitermination factor activity, RNA binding
BFW97_21750	COG0745	RESPONSE REGULATOR receiver
BFW97_21755	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
BFW97_21760	COG2183	response to ionizing radiation
BFW97_21780	COG0596	Alpha beta hydrolase
BFW97_21785	COG1040	competence protein
BFW97_21790	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
BFW97_21790	COG0316	Belongs to the HesB IscA family
BFW97_21795	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
BFW97_21800	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
BFW97_21805	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BFW97_21810	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
BFW97_21815	COG4942	peptidase
BFW97_21825	COG1609	Transcriptional regulator
BFW97_21830	COG0800	Aldolase
BFW97_21835	COG0129	dihydroxy-acid dehydratase activity
BFW97_21840	COG3265	gluconokinase activity
BFW97_21845	COG2610	gluconate transmembrane transporter activity
BFW97_21850	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BFW97_21855	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
BFW97_21865	COG0456	acetyltransferase
BFW97_21875	COG1490	D-aminoacyl-tRNA deacylase activity
BFW97_21880	COG1295	ribonuclease BN
BFW97_21890	COG0174	glutamine synthetase
BFW97_21900	COG3852	Histidine kinase
BFW97_21905	COG2204	response regulator
BFW97_21910	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
BFW97_21915	COG0635	Involved in the biosynthesis of porphyrin-containing compound
BFW97_21925	COG3078	GTPase activator activity
BFW97_21940	COG0218	Necessary for normal cell division and for the maintenance of normal septation
BFW97_21950	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
BFW97_21955	COG0408	coproporphyrinogen oxidase activity
BFW97_21960	COG0009	L-threonylcarbamoyladenylate synthase
BFW97_21970	COG0551	DNA topoisomerase type I activity
BFW97_21975	COG2922	Belongs to the Smg family
BFW97_21980	COG0758	DNA mediated transformation
BFW97_21990	COG0242	peptide deformylase activity
BFW97_21995	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
BFW97_22000	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
BFW97_22000	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
BFW97_22005	COG0569	domain protein
BFW97_22010	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
BFW97_22015	COG1322	Protein conserved in bacteria
BFW97_22035	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BFW97_22040	COG0686	Belongs to the AlaDH PNT family
BFW97_22045	COG0518	GMP synthase (glutamine-hydrolyzing) activity
BFW97_22045	COG0519	Catalyzes the synthesis of GMP from XMP
BFW97_22060	COG1396	sequence-specific DNA binding
BFW97_22065	COG1012	belongs to the aldehyde dehydrogenase family
BFW97_22075	COG2962	Rard protein
BFW97_22085	COG1280	lysine exporter protein (LysE YggA)
BFW97_22095	COG2391	methyltransferase activity
BFW97_22100	COG1280	lysine exporter protein (LysE YggA)
BFW97_22145	COG0583	DNA-binding transcription factor activity
BFW97_22150	COG1943	Transposase
BFW97_22155	COG0210	DNA helicase
BFW97_22180	COG0583	DNA-binding transcription factor activity
BFW97_22200	COG1262	PFAM Formylglycine-generating sulfatase enzyme
BFW97_22205	COG0385	Bile acid
BFW97_22210	COG0531	amino acid
BFW97_22215	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BFW97_22220	COG0531	amino acid
BFW97_22225	COG2731	YhcH YjgK YiaL family protein
BFW97_22230	COG3250	beta-galactosidase activity
BFW97_22235	COG1609	Transcriptional regulator
BFW97_22275	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
BFW97_22280	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BFW97_22280	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BFW97_22285	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
BFW97_22290	COG3074	FtsZ-dependent cytokinesis
BFW97_22300	COG1045	serine acetyltransferase
BFW97_22310	COG0745	RESPONSE REGULATOR receiver
BFW97_22315	COG2205	protein histidine kinase activity
BFW97_22320	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
BFW97_22325	COG0534	Mate efflux family protein
BFW97_22340	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
BFW97_22345	COG2937	Belongs to the GPAT DAPAT family
BFW97_22350	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
BFW97_22355	COG3161	chorismate lyase activity
BFW97_22360	COG1580	Controls the rotational direction of flagella during chemotaxis
BFW97_22370	COG0604	alcohol dehydrogenase
BFW97_22375	COG1609	Transcriptional regulator
BFW97_22395	COG1519	Transferase
BFW97_22400	COG0859	PFAM glycosyl transferase family 9
BFW97_22405	COG0463	Glycosyl transferase, family 2
BFW97_22410	COG0859	PFAM glycosyl transferase family 9
BFW97_22415	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
BFW97_22420	COG2990	Protein conserved in bacteria
BFW97_22425	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
BFW97_22435	COG0267	Belongs to the bacterial ribosomal protein bL33 family
BFW97_22440	COG2003	Belongs to the UPF0758 family
BFW97_22445	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
BFW97_22450	COG0756	dUTP diphosphatase activity
BFW97_22455	COG1309	transcriptional regulator
BFW97_22460	COG0668	transmembrane transport
BFW97_22475	COG0166	Belongs to the GPI family
BFW97_22480	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
BFW97_22485	COG0583	DNA-binding transcription factor activity
BFW97_22525	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
BFW97_22530	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
BFW97_22535	COG1739	Uncharacterized protein family UPF0029
BFW97_22540	COG0006	proline dipeptidase activity
BFW97_22545	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BFW97_22550	COG1024	Enoyl-CoA hydratase
BFW97_22550	COG1250	3-hydroxyacyl-CoA dehydrogenase
BFW97_22555	COG0183	Belongs to the thiolase family
BFW97_22560	COG0745	RESPONSE REGULATOR receiver
BFW97_22565	COG2205	protein histidine kinase activity
BFW97_22580	COG0425	Belongs to the sulfur carrier protein TusA family
BFW97_22585	COG0251	oxidation-reduction process
BFW97_22590	COG2885	chlorophyll binding
BFW97_22595	COG1335	isochorismatase
BFW97_22600	COG2818	Glycosylase
BFW97_22605	COG0752	glycyl-tRNA synthetase alpha subunit
BFW97_22610	COG0751	glycine-tRNA ligase activity
BFW97_22625	COG0529	Catalyzes the synthesis of activated sulfate
BFW97_22625	COG2046	Belongs to the sulfate adenylyltransferase family
BFW97_22645	COG0814	amino acid
BFW97_22650	COG0348	domain, Protein
BFW97_22660	COG0446	pyridine nucleotide-disulphide oxidoreductase
BFW97_22665	COG1773	rubredoxin
BFW97_22665	COG0426	domain, Protein
BFW97_22670	COG3604	Transcriptional regulator
BFW97_22675	COG2188	Transcriptional regulator
BFW97_22690	COG1609	Transcriptional regulator
BFW97_22700	COG0559	Belongs to the binding-protein-dependent transport system permease family
BFW97_22730	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BFW97_22755	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
BFW97_22765	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
BFW97_22770	COG3118	belongs to the thioredoxin family
BFW97_22775	COG0513	Belongs to the DEAD box helicase family
BFW97_22780	COG0248	Ppx GppA phosphatase
BFW97_22795	COG0742	ribosomal rna small subunit methyltransferase
BFW97_22815	COG0084	hydrolase, TatD family'
BFW97_22820	COG0805	protein transport
BFW97_22825	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
BFW97_22835	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
BFW97_22840	COG3165	ubiquinone biosynthetic process from chorismate
BFW97_22850	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
BFW97_22855	COG0402	S-adenosylhomocysteine deaminase activity
BFW97_22895	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
BFW97_22900	COG0848	biopolymer transport protein
BFW97_22905	COG0811	peptide transport
BFW97_22910	COG0811	peptide transport
BFW97_22920	COG2771	luxR family
BFW97_22925	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
BFW97_22930	COG1349	DNA-binding transcription factor activity
BFW97_22935	COG0745	RESPONSE REGULATOR receiver
BFW97_22940	COG2205	protein histidine kinase activity
BFW97_22950	COG4452	Inner membrane protein CreD
BFW97_22955	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
BFW97_22960	COG0355	proton-transporting ATP synthase activity, rotational mechanism
BFW97_22965	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
BFW97_22970	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
BFW97_22975	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
BFW97_22980	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
BFW97_22985	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
BFW97_22995	COG0356	it plays a direct role in the translocation of protons across the membrane
BFW97_23005	COG1475	DNA binding
BFW97_23010	COG1192	Involved in chromosome partitioning
BFW97_23015	COG0357	Ribosomal RNA small subunit methyltransferase G
BFW97_23020	COG0445	tRNA wobble uridine modification
BFW97_23025	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
BFW97_23030	COG4774	siderophore transport
BFW97_23035	COG4615	Cyclic peptide transporter
BFW97_23040	COG1120	ATPase activity
BFW97_23055	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
BFW97_23060	COG0706	membrane insertase activity
BFW97_23065	COG0594	ribonuclease P activity
BFW97_23070	COG0230	Belongs to the bacterial ribosomal protein bL34 family