locus-tag	class	description
BFW41_00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
BFW41_00010	COG0592	DNA-directed DNA polymerase activity
BFW41_00015	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
BFW41_00020	COG0187	DNA topoisomerase II activity
BFW41_00030	COG2378	regulation of single-species biofilm formation
BFW41_00035	COG0071	Belongs to the small heat shock protein (HSP20) family
BFW41_00040	COG0071	Belongs to the small heat shock protein (HSP20) family
BFW41_00045	COG3977	Valine--pyruvate aminotransferase
BFW41_00060	COG2814	Major facilitator Superfamily
BFW41_00065	COG0745	RESPONSE REGULATOR receiver
BFW41_00070	COG2205	protein histidine kinase activity
BFW41_00090	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BFW41_00095	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BFW41_00095	COG4191	Histidine kinase
BFW41_00100	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BFW41_00105	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BFW41_00110	COG1309	transcriptional regulator
BFW41_00140	COG0469	pyruvate kinase activity
BFW41_00145	COG2271	Major facilitator Superfamily
BFW41_00150	COG1840	ABC-type Fe3 transport system, periplasmic component
BFW41_00170	COG0561	phosphatase activity
BFW41_00175	COG2267	carboxylic ester hydrolase activity
BFW41_00180	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BFW41_00185	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
BFW41_00190	COG1758	RNA polymerase activity
BFW41_00200	COG0859	PFAM glycosyl transferase family 9
BFW41_00205	COG3642	lipopolysaccharide core region biosynthetic process
BFW41_00240	COG0589	response to stress
BFW41_00245	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
BFW41_00250	COG3706	GGDEF domain
BFW41_00255	COG1528	Iron-storage protein
BFW41_00260	COG2081	HI0933 family
BFW41_00265	COG2223	nitrite transmembrane transporter activity
BFW41_00285	COG3188	usher protein
BFW41_00310	COG2963	transposase activity
BFW41_00315	COG2801	Transposase and inactivated derivatives
BFW41_00330	COG3275	phosphorelay sensor kinase activity
BFW41_00335	COG3279	Response regulator of the LytR AlgR family
BFW41_00340	COG2223	nitrite transmembrane transporter activity
BFW41_00345	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
BFW41_00350	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
BFW41_00365	COG0583	DNA-binding transcription factor activity
BFW41_00370	COG4206	TonB-dependent receptor
BFW41_00375	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
BFW41_00410	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
BFW41_00415	COG2166	iron-sulfur cluster assembly
BFW41_00420	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
BFW41_00435	COG3245	cytochrome
BFW41_00440	COG1063	alcohol dehydrogenase
BFW41_00445	COG0156	8-amino-7-oxononanoate synthase activity
BFW41_00455	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BFW41_00470	COG3306	glycosyltransferase involved in LPS biosynthesis
BFW41_00490	COG1561	YicC-like family, N-terminal region
BFW41_00495	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
BFW41_00500	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
BFW41_00510	COG0789	Transcriptional regulator
BFW41_00515	COG3706	GGDEF domain
BFW41_00515	COG2203	Gaf domain
BFW41_00515	COG4251	negative regulation of phosphorylation
BFW41_00515	COG5001	Diguanylate cyclase
BFW41_00520	COG3084	Protein conserved in bacteria
BFW41_00530	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
BFW41_00535	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
BFW41_00540	COG3639	organic phosphonate transmembrane transporter activity
BFW41_00545	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
BFW41_00550	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
BFW41_00560	COG1335	isochorismatase
BFW41_00570	COG1683	Conserved Protein
BFW41_00575	COG0204	Acyl-transferase
BFW41_00580	COG0204	Acyl-transferase
BFW41_00585	COG0606	chelatase, subunit chli
BFW41_00595	COG3978	acetolactate synthase activity
BFW41_00600	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BFW41_00605	COG0129	dihydroxy-acid dehydratase activity
BFW41_00625	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
BFW41_00630	COG0254	rRNA binding
BFW41_00635	COG0702	epimerase
BFW41_00640	COG0281	malic enzyme
BFW41_00650	COG2205	protein histidine kinase activity
BFW41_00655	COG0745	RESPONSE REGULATOR receiver
BFW41_00660	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
BFW41_00695	COG4310	Domain of unknown function (DUF2172)
BFW41_00715	COG2089	acid synthase
BFW41_00725	COG1083	cytidylyl-transferase
BFW41_00740	COG1028	Short-chain dehydrogenase reductase Sdr
BFW41_00745	COG0318	PFAM AMP-dependent synthetase and ligase
BFW41_00760	COG1215	transferase activity, transferring glycosyl groups
BFW41_00765	COG1442	glycosyl transferase family 8
BFW41_00790	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
BFW41_00795	COG1086	Polysaccharide biosynthesis protein
BFW41_00800	COG0366	Alpha amylase catalytic
BFW41_00815	COG0443	Heat shock 70 kDa protein
BFW41_00820	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BFW41_00825	COG3045	CreA protein
BFW41_00840	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
BFW41_00845	COG0174	glutamine synthetase
BFW41_00865	COG3842	ATPase activity
BFW41_00870	COG1176	ABC-type spermidine putrescine transport system, permease component I
BFW41_00875	COG1177	transmembrane transport
BFW41_00880	COG2258	MOSC domain
BFW41_00895	COG2050	protein possibly involved in aromatic compounds catabolism
BFW41_00900	COG0514	ATP-dependent DNA helicase (RecQ)
BFW41_00910	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
BFW41_00920	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
BFW41_00925	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
BFW41_00935	COG2239	Acts as a magnesium transporter
BFW41_00940	COG1648	precorrin-2 dehydrogenase activity
BFW41_00940	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
BFW41_00945	COG2116	formate transmembrane transporter activity
BFW41_00950	COG2146	nitrite reductase [NAD(P)H] activity
BFW41_00955	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BFW41_00970	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
BFW41_00975	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
BFW41_00995	COG1595	DNA-templated transcription, initiation
BFW41_01000	COG3806	Anti-sigma factor
BFW41_01005	COG1968	undecaprenyl-diphosphatase activity
BFW41_01010	COG0667	Aldo Keto reductase
BFW41_01015	COG2017	converts alpha-aldose to the beta-anomer
BFW41_01020	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
BFW41_01030	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
BFW41_01035	COG1609	Transcriptional regulator
BFW41_01040	COG3250	beta-galactosidase activity
BFW41_01085	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
BFW41_01090	COG1288	antiporter activity
BFW41_01095	COG1438	arginine binding
BFW41_01100	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
BFW41_01105	COG0540	Belongs to the ATCase OTCase family
BFW41_01120	COG0688	phosphatidylethanolamine metabolic process
BFW41_01135	COG2207	Transcriptional regulator
BFW41_01140	COG1979	alcohol dehydrogenase
BFW41_01145	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
BFW41_01150	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
BFW41_01160	COG3681	Belongs to the UPF0597 family
BFW41_01170	COG0446	pyridine nucleotide-disulphide oxidoreductase
BFW41_01175	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BFW41_01180	COG0564	pseudouridine synthase activity
BFW41_01190	COG0542	response to heat
BFW41_01195	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
BFW41_01200	COG2502	aspartate--ammonia ligase
BFW41_01205	COG1522	sequence-specific DNA binding
BFW41_01215	COG5413	integral membrane protein
BFW41_01235	COG2205	protein histidine kinase activity
BFW41_01245	COG2204	response regulator
BFW41_01260	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
BFW41_01275	COG0745	RESPONSE REGULATOR receiver
BFW41_01280	COG2205	protein histidine kinase activity
BFW41_01290	COG0243	molybdopterin cofactor binding
BFW41_01295	COG3005	denitrification pathway
BFW41_01300	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
BFW41_01320	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
BFW41_01325	COG0569	domain protein
BFW41_01330	COG0812	UDP-N-acetylmuramate dehydrogenase activity
BFW41_01355	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
BFW41_01365	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
BFW41_01370	COG0250	Participates in transcription elongation, termination and antitermination
BFW41_01375	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
BFW41_01380	COG0081	regulation of translation
BFW41_01385	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
BFW41_01390	COG0222	ribosome binding
BFW41_01395	COG0085	RNA polymerase activity
BFW41_01400	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
BFW41_01405	COG2964	Protein conserved in bacteria
BFW41_01410	COG0251	oxidation-reduction process
BFW41_01420	COG2923	Belongs to the DsrF TusC family
BFW41_01425	COG2168	tRNA wobble position uridine thiolation
BFW41_01435	COG0049	tRNA binding
BFW41_01440	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
BFW41_01445	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
BFW41_01450	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
BFW41_01485	COG2252	PERMEase
BFW41_01490	COG2376	Dihydroxyacetone kinase
BFW41_01495	COG1461	Dihydroxyacetone kinase
BFW41_01510	COG3284	Transcriptional regulator
BFW41_01520	COG2957	Belongs to the agmatine deiminase family
BFW41_01525	COG4221	oxidoreductase activity
BFW41_01530	COG0628	permease
BFW41_01535	COG0494	nUDIX hydrolase
BFW41_01560	COG0753	catalase activity
BFW41_01565	COG1247	-acetyltransferase
BFW41_01585	COG2203	Gaf domain
BFW41_01585	COG2199	diguanylate cyclase activity
BFW41_01595	COG3842	ATPase activity
BFW41_01605	COG1176	ABC-type spermidine putrescine transport system, permease component I
BFW41_01630	COG0583	DNA-binding transcription factor activity
BFW41_01640	COG1741	Belongs to the pirin family
BFW41_01645	COG2259	Doxx family
BFW41_01650	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
BFW41_01655	COG1074	ATP-dependent DNA helicase activity
BFW41_01660	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
BFW41_01670	COG0346	lactoylglutathione lyase activity
BFW41_01680	COG3706	GGDEF domain
BFW41_01705	COG0745	RESPONSE REGULATOR receiver
BFW41_01715	COG5001	Diguanylate cyclase
BFW41_01715	COG2203	Gaf domain
BFW41_01715	COG3706	GGDEF domain
BFW41_01715	COG4251	negative regulation of phosphorylation
BFW41_01720	COG4771	TonB-dependent receptor
BFW41_01730	COG1278	Cold shock
BFW41_01750	COG0629	single-stranded DNA binding
BFW41_01755	COG2197	response regulator
BFW41_01760	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
BFW41_01765	COG3706	GGDEF domain
BFW41_01770	COG3047	cAMP biosynthetic process
BFW41_01775	COG0840	transmembrane signaling receptor activity
BFW41_01800	COG3135	benzoate transporter
BFW41_01805	COG1396	sequence-specific DNA binding
BFW41_01835	COG2926	Belongs to the UPF0265 family
BFW41_01845	COG3028	Belongs to the UPF0307 family
BFW41_01850	COG0312	modulator of DNA gyrase
BFW41_01855	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
BFW41_01860	COG5007	Belongs to the BolA IbaG family
BFW41_01870	COG2854	intermembrane phospholipid transfer
BFW41_01875	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
BFW41_01880	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
BFW41_01885	COG1127	ABC transporter
BFW41_01890	COG0517	IMP dehydrogenase activity
BFW41_01890	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
BFW41_01895	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
BFW41_01900	COG3117	lipopolysaccharide transmembrane transporter activity
BFW41_01905	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
BFW41_01910	COG1137	ATPase activity
BFW41_01915	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
BFW41_01925	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BFW41_01930	COG1660	Displays ATPase and GTPase activities
BFW41_01935	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
BFW41_01940	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BFW41_01940	COG3711	transcriptional antiterminator
BFW41_01955	COG3964	amidohydrolase
BFW41_01985	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BFW41_01990	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BFW41_02000	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
BFW41_02005	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
BFW41_02010	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
BFW41_02015	COG0723	plastoquinol--plastocyanin reductase activity
BFW41_02020	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
BFW41_02025	COG2857	Cytochrome c1
BFW41_02030	COG0625	glutathione transferase activity
BFW41_02035	COG2969	positive regulation of protein catabolic process
BFW41_02040	COG2823	Periplasmic or secreted lipoprotein
BFW41_02045	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
BFW41_02050	COG0792	nuclease activity
BFW41_02055	COG3107	peptidoglycan biosynthetic process
BFW41_02060	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
BFW41_02070	COG2001	Belongs to the MraZ family
BFW41_02075	COG0275	rRNA processing
BFW41_02080	COG3116	cell division
BFW41_02085	COG0768	penicillin binding
BFW41_02095	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
BFW41_02100	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
BFW41_02105	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
BFW41_02110	COG0772	Belongs to the SEDS family
BFW41_02115	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
BFW41_02120	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
BFW41_02125	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
BFW41_02130	COG0849	cell division
BFW41_02135	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
BFW41_02140	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
BFW41_02150	COG0653	protein targeting
BFW41_02160	COG0494	nUDIX hydrolase
BFW41_02165	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
BFW41_02170	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
BFW41_02185	COG1459	type II secretion system
BFW41_02190	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
BFW41_02210	COG2186	Transcriptional regulator
BFW41_02215	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
BFW41_02220	COG0508	dehydrogenase complex catalyzes the overall conversion of
BFW41_02225	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BFW41_02235	COG0840	transmembrane signaling receptor activity
BFW41_02240	COG0840	transmembrane signaling receptor activity
BFW41_02245	COG1752	Esterase of the alpha-beta hydrolase superfamily
BFW41_02250	COG1049	propionate catabolic process, 2-methylcitrate cycle
BFW41_02255	COG2200	EAL domain
BFW41_02265	COG1280	lysine exporter protein (LysE YggA)
BFW41_02275	COG0523	cobalamin synthesis protein
BFW41_02280	COG0477	Major facilitator Superfamily
BFW41_02295	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
BFW41_02300	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
BFW41_02345	COG0835	chemotaxis
BFW41_02345	COG0784	Response regulator, receiver
BFW41_02355	COG1444	tRNA N-acetyltransferase activity
BFW41_02380	COG1803	Methylglyoxal synthase
BFW41_02395	COG0252	asparaginase activity
BFW41_02415	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BFW41_02415	COG1263	PTS System
BFW41_02420	COG0366	Alpha amylase catalytic
BFW41_02425	COG0110	maltose O-acetyltransferase activity
BFW41_02430	COG1522	sequence-specific DNA binding
BFW41_02435	COG5006	permease, DMT superfamily
BFW41_02445	COG1012	belongs to the aldehyde dehydrogenase family
BFW41_02450	COG1177	transmembrane transport
BFW41_02455	COG1176	ABC-type spermidine putrescine transport system, permease component I
BFW41_02460	COG3842	ATPase activity
BFW41_02465	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
BFW41_02470	COG0583	DNA-binding transcription factor activity
BFW41_02475	COG1757	Na H antiporter
BFW41_02515	COG0297	glycogen (starch) synthase activity
BFW41_02520	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
BFW41_02525	COG2813	Specifically methylates the guanine in position
BFW41_02530	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BFW41_02535	COG2203	Gaf domain
BFW41_02535	COG3706	GGDEF domain
BFW41_02535	COG4251	negative regulation of phosphorylation
BFW41_02535	COG5001	Diguanylate cyclase
BFW41_02545	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BFW41_02555	COG2995	paraquat-inducible protein a
BFW41_02560	COG3008	intermembrane lipid transfer
BFW41_02560	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
BFW41_02565	COG3009	Protein conserved in bacteria
BFW41_02570	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
BFW41_02570	COG2885	chlorophyll binding
BFW41_02580	COG3240	lipase activity
BFW41_02585	COG3111	PFAM Bacterial OB fold (BOF) protein
BFW41_02595	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
BFW41_02600	COG1194	a g-specific adenine glycosylase
BFW41_02610	COG3409	Peptidoglycan-binding domain 1 protein
BFW41_02610	COG3267	Type II secretory pathway component ExeA
BFW41_02615	COG0617	tRNA 3'-terminal CCA addition
BFW41_02630	COG1346	cytolysis
BFW41_02635	COG1380	Effector of murein hydrolase LrgA
BFW41_02640	COG0583	DNA-binding transcription factor activity
BFW41_02670	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
BFW41_02675	COG0306	phosphate transporter
BFW41_02680	COG1392	Phosphate transport regulator
BFW41_02695	COG1560	Kdo2-lipid A biosynthetic process
BFW41_02700	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
BFW41_02700	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
BFW41_02705	COG1538	Outer membrane efflux protein
BFW41_02710	COG0494	nUDIX hydrolase
BFW41_02715	COG3151	Protein conserved in bacteria
BFW41_02725	COG3150	esterase
BFW41_02730	COG1051	belongs to the nudix hydrolase family
BFW41_02745	COG1566	PFAM secretion protein HlyD family protein
BFW41_02750	COG1289	transmembrane transporter activity
BFW41_02755	COG0187	DNA topoisomerase II activity
BFW41_02765	COG0583	DNA-binding transcription factor activity
BFW41_02805	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BFW41_02825	COG0204	Acyl-transferase
BFW41_02830	COG1842	Phage shock protein A
BFW41_02845	COG2827	Endonuclease containing a URI domain
BFW41_02855	COG2962	Rard protein
BFW41_02860	COG1573	uracil-dna glycosylase
BFW41_02865	COG0697	spore germination
BFW41_02870	COG0583	DNA-binding transcription factor activity
BFW41_02875	COG1108	ABC-type Mn2 Zn2 transport systems permease components
BFW41_02880	COG1121	(ABC) transporter
BFW41_02885	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
BFW41_02905	COG0739	heme binding
BFW41_02915	COG3068	Protein conserved in bacteria
BFW41_02935	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
BFW41_02940	COG1546	Belongs to the CinA family
BFW41_02945	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
BFW41_02955	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
BFW41_02960	COG0527	aspartate kinase activity
BFW41_02965	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
BFW41_03000	COG1686	Belongs to the peptidase S11 family
BFW41_03005	COG0586	Pfam SNARE associated Golgi protein
BFW41_03010	COG1253	flavin adenine dinucleotide binding
BFW41_03015	COG0525	valine-tRNA ligase activity
BFW41_03020	COG2927	DNA polymerase III (CHI subunit)
BFW41_03025	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
BFW41_03030	COG0795	lipopolysaccharide-transporting ATPase activity
BFW41_03035	COG0795	lipopolysaccharide-transporting ATPase activity
BFW41_03050	COG0004	ammonium transporteR
BFW41_03055	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
BFW41_03065	COG0084	hydrolase, TatD family'
BFW41_03070	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BFW41_03080	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
BFW41_03085	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
BFW41_03090	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
BFW41_03095	COG0813	purine-nucleoside phosphorylase activity
BFW41_03100	COG5002	protein histidine kinase activity
BFW41_03100	COG5001	Diguanylate cyclase
BFW41_03100	COG3447	MASE1 domain protein
BFW41_03110	COG0560	Phosphoserine phosphatase
BFW41_03135	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
BFW41_03140	COG0776	regulation of translation
BFW41_03150	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
BFW41_03180	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
BFW41_03185	COG0513	Belongs to the DEAD box helicase family
BFW41_03190	COG3022	response to hydroperoxide
BFW41_03195	COG2805	Type II/IV secretion system protein
BFW41_03205	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
BFW41_03210	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
BFW41_03215	COG0762	integral membrane protein
BFW41_03220	COG1872	DUF167
BFW41_03235	COG4166	transmembrane transport
BFW41_03255	COG1024	Enoyl-CoA hydratase
BFW41_03270	COG4221	oxidoreductase activity
BFW41_03275	COG0442	prolyl-tRNA aminoacylation
BFW41_03280	COG0840	transmembrane signaling receptor activity
BFW41_03285	COG0632	four-way junction helicase activity
BFW41_03290	COG2255	four-way junction helicase activity
BFW41_03295	COG1271	oxidase subunit
BFW41_03300	COG1294	oxidase, subunit
BFW41_03305	COG4890	Cyd operon protein YbgT
BFW41_03310	COG3790	cyd operon protein YbgE
BFW41_03315	COG0824	Thioesterase
BFW41_03320	COG0811	peptide transport
BFW41_03335	COG0823	Involved in the tonB-independent uptake of proteins
BFW41_03340	COG2885	chlorophyll binding
BFW41_03345	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
BFW41_03420	COG0840	transmembrane signaling receptor activity
BFW41_03425	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
BFW41_03430	COG0676	glucose-6-phosphate 1-epimerase activity
BFW41_03435	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
BFW41_03440	COG1640	4-alpha-glucanotransferase
BFW41_03445	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
BFW41_03465	COG1051	belongs to the nudix hydrolase family
BFW41_03470	COG2130	NADP-dependent
BFW41_03475	COG1764	response to oxidative stress
BFW41_03480	COG1846	Transcriptional regulator
BFW41_03495	COG1522	sequence-specific DNA binding
BFW41_03510	COG0561	phosphatase activity
BFW41_03525	COG0733	neurotransmitter:sodium symporter activity
BFW41_03535	COG0733	neurotransmitter:sodium symporter activity
BFW41_03560	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BFW41_03575	COG1794	racemase activity, acting on amino acids and derivatives
BFW41_03590	COG2731	YhcH YjgK YiaL family protein
BFW41_03600	COG0668	transmembrane transport
BFW41_03610	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BFW41_03645	COG0583	DNA-binding transcription factor activity
BFW41_03650	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
BFW41_03660	COG0488	(ABC) transporter
BFW41_03665	COG0517	IMP dehydrogenase activity
BFW41_03665	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
BFW41_03670	COG1585	Membrane protein implicated in regulation of membrane protease activity
BFW41_03675	COG0330	HflC and HflK could
BFW41_03680	COG1648	precorrin-2 dehydrogenase activity
BFW41_03680	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
BFW41_03685	COG0175	sulfate reduction
BFW41_03690	COG2895	sulfate adenylyltransferase (ATP) activity
BFW41_03695	COG0471	metal ion transport
BFW41_03695	COG3273	potassium ion transport
BFW41_03700	COG0529	Catalyzes the synthesis of activated sulfate
BFW41_03745	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
BFW41_03760	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
BFW41_03765	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
BFW41_03770	COG0163	prenyltransferase activity
BFW41_03785	COG1131	(ABC) transporter
BFW41_03790	COG0842	Transport permease protein
BFW41_03795	COG1775	2-hydroxyglutaryl-CoA dehydratase, D-component
BFW41_03800	COG1924	4 iron, 4 sulfur cluster binding
BFW41_03820	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
BFW41_03825	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
BFW41_03840	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
BFW41_03845	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
BFW41_03850	COG1489	DNA binding
BFW41_03860	COG1643	Atp-dependent helicase
BFW41_03865	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BFW41_03870	COG0346	lactoylglutathione lyase activity
BFW41_03880	COG2076	Multidrug Resistance protein
BFW41_03890	COG0784	Response regulator, receiver
BFW41_03890	COG3437	response regulator, receiver
BFW41_03900	COG0671	phosphoesterase, PA-phosphatase related
BFW41_03915	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
BFW41_03920	COG0038	chloride channel
BFW41_03930	COG0316	Belongs to the HesB IscA family
BFW41_03955	COG1280	lysine exporter protein (LysE YggA)
BFW41_03960	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
BFW41_03975	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BFW41_04005	COG0745	RESPONSE REGULATOR receiver
BFW41_04010	COG3104	oligopeptide transport
BFW41_04015	COG1210	Utp--glucose-1-phosphate uridylyltransferase
BFW41_04020	COG1555	photosystem II stabilization
BFW41_04030	COG2350	Protein conserved in bacteria
BFW41_04035	COG2917	probably involved in intracellular septation
BFW41_04040	COG0076	glutamate decarboxylase activity
BFW41_04045	COG1272	protein, Hemolysin III
BFW41_04050	COG0569	domain protein
BFW41_04050	COG2985	domain, Protein
BFW41_04110	COG0835	chemotaxis
BFW41_04110	COG0784	Response regulator, receiver
BFW41_04115	COG2755	lipolytic protein G-D-S-L family
BFW41_04120	COG4181	ATPase activity
BFW41_04125	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
BFW41_04130	COG1090	epimerase
BFW41_04135	COG2200	EAL domain
BFW41_04140	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BFW41_04145	COG4935	Belongs to the peptidase S8 family
BFW41_04145	COG2234	aminopeptidase activity
BFW41_04150	COG0220	tRNA (guanine-N7-)-methyltransferase activity
BFW41_04155	COG3171	Protein conserved in bacteria
BFW41_04160	COG2066	Belongs to the glutaminase family
BFW41_04165	COG2897	thiosulfate sulfurtransferase activity
BFW41_04175	COG1132	(ABC) transporter
BFW41_04195	COG4412	M6 family metalloprotease domain protein
BFW41_04195	COG3291	Pkd domain containing protein
BFW41_04200	COG3076	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome
BFW41_04205	COG5001	Diguanylate cyclase
BFW41_04205	COG3300	MHYT domain
BFW41_04220	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
BFW41_04225	COG3059	membrane
BFW41_04240	COG4628	conserved protein (DUF2132)
BFW41_04245	COG0688	phosphatidylethanolamine metabolic process
BFW41_04250	COG1162	GTPase activity
BFW41_04255	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
BFW41_04295	COG1278	Cold shock
BFW41_04305	COG0840	transmembrane signaling receptor activity
BFW41_04310	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
BFW41_04360	COG0848	biopolymer transport protein
BFW41_04365	COG0811	peptide transport
BFW41_04370	COG0811	peptide transport
BFW41_04385	COG4174	ABC transporter (Permease)
BFW41_04390	COG4239	(ABC) transporter, permease
BFW41_04400	COG0444	Belongs to the ABC transporter superfamily
BFW41_04405	COG4608	Belongs to the ABC transporter superfamily
BFW41_04410	COG2195	Cleaves the N-terminal amino acid of tripeptides
BFW41_04420	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
BFW41_04440	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
BFW41_04470	COG0243	molybdopterin cofactor binding
BFW41_04485	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BFW41_04485	COG1116	anion transmembrane transporter activity
BFW41_04490	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BFW41_04495	COG1116	anion transmembrane transporter activity
BFW41_04500	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BFW41_04500	COG2146	nitrite reductase [NAD(P)H] activity
BFW41_04505	COG2146	nitrite reductase [NAD(P)H] activity
BFW41_04505	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BFW41_04510	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BFW41_04515	COG2313	pseudouridylate synthase activity
BFW41_04525	COG1858	cytochrome C peroxidase
BFW41_04560	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BFW41_04565	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BFW41_04615	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
BFW41_04625	COG1028	Short-chain dehydrogenase reductase Sdr
BFW41_04640	COG0521	Mo-molybdopterin cofactor biosynthetic process
BFW41_04650	COG2966	Psort location CytoplasmicMembrane, score
BFW41_04655	COG3610	response to peptide
BFW41_04675	COG4175	Glycine betaine
BFW41_04680	COG4176	ABC-type proline glycine betaine transport system permease component
BFW41_04685	COG2113	Glycine betaine
BFW41_04690	COG0175	sulfate reduction
BFW41_04695	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BFW41_04700	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
BFW41_04705	COG0384	phenazine biosynthesis protein PhzF
BFW41_04710	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
BFW41_04715	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
BFW41_04725	COG0786	glutamate:sodium symporter activity
BFW41_04730	COG0252	asparaginase activity
BFW41_04735	COG3139	Protein of unknown function (DUF1315)
BFW41_04755	COG0616	signal peptide processing
BFW41_04760	COG0446	pyridine nucleotide-disulphide oxidoreductase
BFW41_04760	COG1902	pentaerythritol trinitrate reductase activity
BFW41_04765	COG0778	Nitroreductase
BFW41_04780	COG0110	maltose O-acetyltransferase activity
BFW41_04785	COG2264	protein methyltransferase activity
BFW41_04790	COG0604	alcohol dehydrogenase
BFW41_04795	COG0583	DNA-binding transcription factor activity
BFW41_04800	COG1263	PTS System
BFW41_04800	COG2190	(PTS) system
BFW41_04800	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BFW41_04805	COG4145	pantothenate transmembrane transporter activity
BFW41_04815	COG0439	Biotin carboxylase
BFW41_04820	COG0511	ligase activity, forming carbon-carbon bonds
BFW41_04825	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
BFW41_04830	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BFW41_04840	COG5001	Diguanylate cyclase
BFW41_04840	COG3300	MHYT domain
BFW41_04860	COG3381	protein complex oligomerization
BFW41_04875	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
BFW41_04885	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
BFW41_04890	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BFW41_04890	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BFW41_04910	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
BFW41_04915	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
BFW41_04920	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
BFW41_04925	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
BFW41_04950	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
BFW41_04955	COG0142	geranyltranstransferase activity
BFW41_04960	COG1722	exodeoxyribonuclease VII activity
BFW41_04965	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
BFW41_04970	COG1360	Flagellar Motor Protein
BFW41_04975	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
BFW41_04985	COG1534	Rna-binding protein
BFW41_04990	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
BFW41_04995	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
BFW41_05000	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
BFW41_05005	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
BFW41_05010	COG0149	triose-phosphate isomerase activity
BFW41_05015	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
BFW41_05030	COG0779	Required for maturation of 30S ribosomal subunits
BFW41_05035	COG0195	Participates in both transcription termination and antitermination
BFW41_05040	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
BFW41_05045	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
BFW41_05050	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
BFW41_05055	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
BFW41_05060	COG1185	polyribonucleotide nucleotidyltransferase activity
BFW41_05065	COG2211	Major facilitator Superfamily
BFW41_05075	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
BFW41_05085	COG0114	fumarate hydratase activity
BFW41_05095	COG1966	Carbon starvation protein
BFW41_05100	COG3279	Response regulator of the LytR AlgR family
BFW41_05105	COG3275	phosphorelay sensor kinase activity
BFW41_05170	COG0312	modulator of DNA gyrase
BFW41_05175	COG0312	modulator of DNA gyrase
BFW41_05180	COG0716	FMN binding
BFW41_05185	COG4974	Belongs to the 'phage' integrase family
BFW41_05190	COG2199	diguanylate cyclase activity
BFW41_05190	COG2203	Gaf domain
BFW41_05195	COG1970	mechanosensitive ion channel activity
BFW41_05200	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
BFW41_05210	COG0789	Transcriptional regulator
BFW41_05225	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
BFW41_05230	COG3545	Serine hydrolase
BFW41_05240	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
BFW41_05245	COG0321	lipoyl(octanoyl) transferase activity
BFW41_05250	COG2921	Belongs to the UPF0250 family
BFW41_05255	COG1686	Belongs to the peptidase S11 family
BFW41_05260	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
BFW41_05265	COG2951	lytic endotransglycosylase activity
BFW41_05270	COG0772	Belongs to the SEDS family
BFW41_05275	COG0768	penicillin binding
BFW41_05280	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
BFW41_05285	COG0799	negative regulation of ribosome biogenesis
BFW41_05290	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
BFW41_05310	COG0495	leucyl-tRNA aminoacylation
BFW41_05315	COG2888	peptidyl-tyrosine sulfation
BFW41_05320	COG0815	Transfers the fatty acyl group on membrane lipoproteins
BFW41_05325	COG4535	Mg2 and Co2 transporter CorC
BFW41_05330	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
BFW41_05335	COG1702	phosphate starvation-inducible protein PhoH
BFW41_05340	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
BFW41_05345	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BFW41_05350	COG1335	isochorismatase
BFW41_05360	COG3706	GGDEF domain
BFW41_05375	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BFW41_05385	COG3706	GGDEF domain
BFW41_05395	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BFW41_05405	COG3647	Membrane
BFW41_05410	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
BFW41_05420	COG0516	GMP reductase activity
BFW41_05430	COG0642	Histidine kinase
BFW41_05435	COG0745	RESPONSE REGULATOR receiver
BFW41_05470	COG3214	Protein conserved in bacteria
BFW41_05495	COG3029	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
BFW41_05500	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
BFW41_05505	COG1053	succinate dehydrogenase
BFW41_05515	COG0584	glycerophosphoryl diester phosphodiesterase
BFW41_05520	COG1511	domain protein
BFW41_05520	COG3264	Mechanosensitive ion channel
BFW41_05530	COG0739	heme binding
BFW41_05545	COG0583	DNA-binding transcription factor activity
BFW41_05565	COG0583	DNA-binding transcription factor activity
BFW41_05570	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
BFW41_05600	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
BFW41_05605	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
BFW41_05615	COG0338	D12 class N6 adenine-specific DNA methyltransferase
BFW41_05620	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
BFW41_05625	COG0546	phosphoglycolate phosphatase activity
BFW41_05630	COG0180	Tryptophanyl-tRNA synthetase
BFW41_05645	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
BFW41_05655	COG1012	belongs to the aldehyde dehydrogenase family
BFW41_05675	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BFW41_05685	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
BFW41_05685	COG1013	pyruvate-flavodoxin oxidoreductase activity
BFW41_05685	COG0674	pyruvate-flavodoxin oxidoreductase activity
BFW41_05685	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BFW41_05695	COG0366	Alpha amylase catalytic
BFW41_05715	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
BFW41_05725	COG0471	metal ion transport
BFW41_05725	COG0490	domain, Protein
BFW41_05770	COG0012	GTP binding
BFW41_05775	COG0193	aminoacyl-tRNA hydrolase activity
BFW41_05780	COG0737	Belongs to the 5'-nucleotidase family
BFW41_05785	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
BFW41_05800	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
BFW41_05805	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
BFW41_05810	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
BFW41_05815	COG2890	protein-(glutamine-N5) methyltransferase activity
BFW41_05825	COG2912	Transglutaminase-like superfamily
BFW41_05830	COG2877	3-deoxy-8-phosphooctulonate synthase activity
BFW41_05835	COG1301	dicarboxylic acid transport
BFW41_05845	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
BFW41_05860	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
BFW41_05865	COG1115	amino acid carrier protein
BFW41_05880	COG0714	Associated with various cellular activities
BFW41_05905	COG3104	oligopeptide transport
BFW41_05910	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
BFW41_05915	COG1678	Uncharacterized ACR, COG1678
BFW41_05925	COG0189	ligase activity
BFW41_05930	COG1385	rRNA (uridine-N3-)-methyltransferase activity
BFW41_05940	COG3091	SprT-like family
BFW41_05950	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
BFW41_05970	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
BFW41_05975	COG0739	heme binding
BFW41_05980	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
BFW41_05985	COG3408	Glycogen debranching enzyme
BFW41_05985	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
BFW41_05995	COG1881	PFAM PEBP family protein
BFW41_06005	COG0583	DNA-binding transcription factor activity
BFW41_06015	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
BFW41_06025	COG0583	DNA-binding transcription factor activity
BFW41_06030	COG1028	Short-chain dehydrogenase reductase Sdr
BFW41_06035	COG0616	signal peptide processing
BFW41_06040	COG3724	N-succinylarginine dihydrolase activity
BFW41_06045	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
BFW41_06055	COG0840	transmembrane signaling receptor activity
BFW41_06065	COG2971	BadF BadG BcrA BcrD
BFW41_06075	COG4608	Belongs to the ABC transporter superfamily
BFW41_06080	COG0444	Belongs to the ABC transporter superfamily
BFW41_06085	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BFW41_06090	COG0601	transmembrane transport
BFW41_06095	COG4166	transmembrane transport
BFW41_06130	COG3220	belongs to the UPF0276 family
BFW41_06160	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
BFW41_06165	COG1289	transmembrane transporter activity
BFW41_06170	COG0303	'Molybdopterin
BFW41_06175	COG0746	molybdenum cofactor guanylyltransferase activity
BFW41_06185	COG4662	Binding-protein-dependent transport system inner membrane component
BFW41_06195	COG2204	response regulator
BFW41_06200	COG3852	Histidine kinase
BFW41_06205	COG1910	domain protein
BFW41_06210	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
BFW41_06245	COG3383	formate dehydrogenase (NAD+) activity
BFW41_06250	COG0437	4 iron, 4 sulfur cluster binding
BFW41_06265	COG0281	malic enzyme
BFW41_06275	COG2706	6-phosphogluconolactonase activity
BFW41_06285	COG1196	nuclear chromosome segregation
BFW41_06285	COG3264	Mechanosensitive ion channel
BFW41_06290	COG0469	pyruvate kinase activity
BFW41_06305	COG4651	solute:proton antiporter activity
BFW41_06305	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
BFW41_06315	COG2974	May be involved in recombination
BFW41_06325	COG0420	3'-5' exonuclease activity
BFW41_06330	COG0419	ATPase involved in DNA repair
BFW41_06340	COG3038	cytochrome b561
BFW41_06350	COG3706	GGDEF domain
BFW41_06350	COG0745	RESPONSE REGULATOR receiver
BFW41_06355	COG2190	(PTS) system
BFW41_06365	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
BFW41_06370	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
BFW41_06375	COG0542	response to heat
BFW41_06390	COG1720	tRNA m6t6A37 methyltransferase activity
BFW41_06410	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
BFW41_06415	COG4988	ABC transporter
BFW41_06430	COG0745	RESPONSE REGULATOR receiver
BFW41_06440	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
BFW41_06455	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
BFW41_06460	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
BFW41_06470	COG0083	homoserine kinase activity
BFW41_06475	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
BFW41_06480	COG4319	ketosteroid isomerase
BFW41_06495	COG0488	(ABC) transporter
BFW41_06505	COG0813	purine-nucleoside phosphorylase activity
BFW41_06520	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BFW41_06520	COG2205	protein histidine kinase activity
BFW41_06525	COG3384	dioxygenase
BFW41_06535	COG1283	sodium-dependent phosphate transmembrane transporter activity
BFW41_06545	COG0531	amino acid
BFW41_06555	COG0531	amino acid
BFW41_06570	COG1917	Cupin 2, conserved barrel domain protein
BFW41_06570	COG1396	sequence-specific DNA binding
BFW41_06575	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BFW41_06590	COG3152	Membrane
BFW41_06610	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
BFW41_06615	COG2375	cellular response to nickel ion
BFW41_06620	COG1538	Outer membrane efflux protein
BFW41_06625	COG1136	(ABC) transporter
BFW41_06625	COG0577	efflux transmembrane transporter activity
BFW41_06630	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BFW41_06640	COG1227	inorganic diphosphatase activity
BFW41_06645	COG0497	DNA recombination
BFW41_06650	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
BFW41_06655	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
BFW41_06660	COG0443	Heat shock 70 kDa protein
BFW41_06665	COG0484	heat shock protein binding
BFW41_06695	COG1285	pathogenesis
BFW41_06710	COG0640	Transcriptional regulator
BFW41_06740	COG0095	Lipoate-protein ligase
BFW41_06760	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BFW41_06765	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BFW41_06790	COG0708	Exodeoxyribonuclease III
BFW41_06850	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
BFW41_06855	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
BFW41_06860	COG1845	cytochrome c oxidase, subunit III
BFW41_06865	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
BFW41_06870	COG0109	protoheme IX farnesyltransferase activity
BFW41_06875	COG2814	Major facilitator Superfamily
BFW41_06885	COG2175	clavaminate synthase activity
BFW41_06890	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BFW41_06895	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
BFW41_06900	COG4521	taurine ABC transporter
BFW41_06910	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BFW41_06980	COG0159	tryptophan synthase activity
BFW41_06985	COG0133	tryptophan synthase activity
BFW41_06990	COG0135	phosphoribosylanthranilate isomerase activity
BFW41_06990	COG0134	indole-3-glycerol-phosphate synthase activity
BFW41_06995	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
BFW41_07000	COG0512	Glutamine amidotransferase of anthranilate synthase
BFW41_07000	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
BFW41_07005	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
BFW41_07015	COG0009	L-threonylcarbamoyladenylate synthase
BFW41_07025	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
BFW41_07035	COG1946	Acyl-CoA thioesterase
BFW41_07055	COG1309	transcriptional regulator
BFW41_07060	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BFW41_07065	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BFW41_07070	COG1538	Outer membrane efflux protein
BFW41_07080	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
BFW41_07125	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
BFW41_07130	COG1091	dTDP-4-dehydrorhamnose reductase activity
BFW41_07145	COG3132	Protein of unknown function, DUF480
BFW41_07185	COG1278	Cold shock
BFW41_07215	COG0697	spore germination
BFW41_07220	COG1349	DNA-binding transcription factor activity
BFW41_07230	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
BFW41_07235	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
BFW41_07250	COG1187	pseudouridine synthase activity
BFW41_07265	COG0622	Phosphoesterase
BFW41_07280	COG1261	Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly
BFW41_07285	COG0784	Response regulator, receiver
BFW41_07285	COG0835	chemotaxis
BFW41_07290	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
BFW41_07295	COG1815	bacterial-type flagellum-dependent cell motility
BFW41_07300	COG1558	bacterial-type flagellum-dependent cell motility
BFW41_07315	COG4787	bacterial-type flagellum-dependent cell motility
BFW41_07320	COG4786	Flagellar basal body rod
BFW41_07325	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
BFW41_07330	COG1706	bacterial-type flagellum-dependent cell motility
BFW41_07335	COG1705	Flagellar rod assembly protein muramidase FlgJ
BFW41_07335	COG3951	Flagellar rod assembly protein muramidase FlgJ
BFW41_07340	COG1256	bacterial-type flagellum assembly
BFW41_07350	COG2239	Acts as a magnesium transporter
BFW41_07355	COG0248	Ppx GppA phosphatase
BFW41_07360	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
BFW41_07365	COG2716	regulation of RNA biosynthetic process
BFW41_07375	COG2204	response regulator
BFW41_07380	COG3852	Histidine kinase
BFW41_07385	COG2204	response regulator
BFW41_07390	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
BFW41_07395	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
BFW41_07400	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
BFW41_07405	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
BFW41_07425	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
BFW41_07435	COG0590	tRNA wobble adenosine to inosine editing
BFW41_07440	COG0573	inorganic phosphate transmembrane transporter activity
BFW41_07445	COG0581	inorganic phosphate transmembrane transporter activity
BFW41_07455	COG0704	Plays a role in the regulation of phosphate uptake
BFW41_07460	COG1253	flavin adenine dinucleotide binding
BFW41_07475	COG0531	amino acid
BFW41_07490	COG1126	abc transporter atp-binding protein
BFW41_07495	COG0765	amino acid transport
BFW41_07500	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BFW41_07505	COG3706	GGDEF domain
BFW41_07510	COG2271	Major facilitator Superfamily
BFW41_07525	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
BFW41_07555	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
BFW41_07560	COG0477	Major facilitator Superfamily
BFW41_07565	COG0123	including yeast histone deacetylase and acetoin utilization protein
BFW41_07575	COG1199	ATP-dependent helicase activity
BFW41_07580	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
BFW41_07590	COG1448	Aminotransferase
BFW41_07595	COG0433	COG0433 Predicted ATPase
BFW41_07610	COG0658	competence protein
BFW41_07610	COG2333	competence protein COMEC
BFW41_07620	COG1663	tetraacyldisaccharide 4'-kinase activity
BFW41_07625	COG2835	tetraacyldisaccharide 4'-kinase activity
BFW41_07630	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
BFW41_07635	COG2197	response regulator
BFW41_07640	COG0322	excinuclease ABC activity
BFW41_07695	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
BFW41_07715	COG0582	viral genome integration into host DNA
BFW41_07735	COG2314	TM2 domain
BFW41_07770	COG2963	transposase activity
BFW41_07775	COG2801	Transposase and inactivated derivatives
BFW41_07780	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
BFW41_07790	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
BFW41_07810	COG2203	Gaf domain
BFW41_07810	COG2199	diguanylate cyclase activity
BFW41_07840	COG2119	membrane
BFW41_07845	COG0023	Translation Initiation Factor
BFW41_07870	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
BFW41_07885	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BFW41_07885	COG2205	protein histidine kinase activity
BFW41_07895	COG4138	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system
BFW41_07905	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
BFW41_07910	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
BFW41_07915	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
BFW41_07920	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
BFW41_07925	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
BFW41_07935	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
BFW41_07940	COG0505	Belongs to the CarA family
BFW41_07945	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
BFW41_07950	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
BFW41_07985	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BFW41_07990	COG0513	Belongs to the DEAD box helicase family
BFW41_08000	COG4104	PAAR repeat-containing protein
BFW41_08015	COG0789	Transcriptional regulator
BFW41_08030	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BFW41_08035	COG0765	amino acid transport
BFW41_08045	COG0493	'glutamate synthase
BFW41_08050	COG0067	glutamate synthase
BFW41_08050	COG0069	glutamate synthase activity
BFW41_08050	COG0070	glutamate synthase
BFW41_08060	COG1242	4 iron, 4 sulfur cluster binding
BFW41_08120	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
BFW41_08125	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
BFW41_08125	COG0574	Belongs to the PEP-utilizing enzyme family
BFW41_08170	COG1464	Belongs to the NlpA lipoprotein family
BFW41_08175	COG0671	phosphoesterase, PA-phosphatase related
BFW41_08180	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
BFW41_08185	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
BFW41_08195	COG0101	tRNA pseudouridine synthase activity
BFW41_08200	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
BFW41_08205	COG0285	dihydrofolate synthase activity
BFW41_08210	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
BFW41_08215	COG2920	part of a sulfur-relay system
BFW41_08220	COG1289	transmembrane transporter activity
BFW41_08225	COG0670	Belongs to the BI1 family
BFW41_08245	COG2194	sulfuric ester hydrolase activity
BFW41_08255	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
BFW41_08255	COG0392	lysyltransferase activity
BFW41_08265	COG0840	transmembrane signaling receptor activity
BFW41_08270	COG5001	Diguanylate cyclase
BFW41_08275	COG0564	pseudouridine synthase activity
BFW41_08290	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
BFW41_08300	COG0625	glutathione transferase activity
BFW41_08305	COG0625	glutathione transferase activity
BFW41_08315	COG0367	asparagine synthase
BFW41_08325	COG4651	solute:proton antiporter activity
BFW41_08325	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
BFW41_08330	COG0647	UMP catabolic process
BFW41_08335	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
BFW41_08340	COG1902	pentaerythritol trinitrate reductase activity
BFW41_08345	COG1253	flavin adenine dinucleotide binding
BFW41_08355	COG0277	FAD linked oxidase domain protein
BFW41_08355	COG0247	lactate metabolic process
BFW41_08365	COG2050	protein possibly involved in aromatic compounds catabolism
BFW41_08375	COG2056	Na+-H+ antiporter family
BFW41_08380	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
BFW41_08395	COG0346	lactoylglutathione lyase activity
BFW41_08400	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
BFW41_08410	COG4659	FMN binding
BFW41_08415	COG4658	electron transport chain
BFW41_08425	COG2878	Part of a membrane complex involved in electron transport
BFW41_08430	COG4657	Part of a membrane complex involved in electron transport
BFW41_08435	COG0697	spore germination
BFW41_08450	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
BFW41_08455	COG1288	antiporter activity
BFW41_08460	COG0436	Aminotransferase
BFW41_08470	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
BFW41_08475	COG2027	D-alanyl-D-alanine carboxypeptidase
BFW41_08480	COG1061	Type III restriction enzyme res subunit
BFW41_08485	COG1566	PFAM secretion protein HlyD family protein
BFW41_08495	COG1966	Carbon starvation protein
BFW41_08500	COG3279	Response regulator of the LytR AlgR family
BFW41_08505	COG3275	phosphorelay sensor kinase activity
BFW41_08510	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
BFW41_08510	COG2199	diguanylate cyclase activity
BFW41_08515	COG1454	alcohol dehydrogenase
BFW41_08515	COG1012	belongs to the aldehyde dehydrogenase family
BFW41_08525	COG2095	MarC family integral membrane protein
BFW41_08535	COG0601	transmembrane transport
BFW41_08540	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BFW41_08545	COG0444	Belongs to the ABC transporter superfamily
BFW41_08555	COG0861	Integral membrane protein TerC family
BFW41_08560	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
BFW41_08570	COG1301	dicarboxylic acid transport
BFW41_08585	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
BFW41_08590	COG0582	viral genome integration into host DNA
BFW41_08640	COG2974	May be involved in recombination
BFW41_08665	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
BFW41_08700	COG3646	Phage regulatory protein
BFW41_08700	COG3645	SOS response
BFW41_08920	COG0537	adenosine 5'-monophosphoramidase activity
BFW41_08955	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BFW41_08960	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BFW41_08970	COG2354	Protein conserved in bacteria
BFW41_08985	COG2233	PERMEase
BFW41_08995	COG1252	NADH dehydrogenase
BFW41_09015	COG0393	Putative heavy-metal-binding
BFW41_09025	COG1648	precorrin-2 dehydrogenase activity
BFW41_09025	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
BFW41_09030	COG2221	Nitrite and sulphite reductase 4Fe-4S
BFW41_09045	COG4667	esterase of the alpha-beta hydrolase superfamily
BFW41_09050	COG1619	proteins homologs of microcin C7 resistance protein MccF
BFW41_09055	COG1368	sulfuric ester hydrolase activity
BFW41_09065	COG0527	aspartate kinase activity
BFW41_09070	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
BFW41_09070	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
BFW41_09075	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BFW41_09100	COG0596	Alpha beta hydrolase
BFW41_09105	COG0346	lactoylglutathione lyase activity
BFW41_09115	COG0583	DNA-binding transcription factor activity
BFW41_09120	COG1620	l-lactate permease
BFW41_09125	COG0247	lactate metabolic process
BFW41_09130	COG1139	Iron-sulfur cluster binding protein
BFW41_09165	COG1136	(ABC) transporter
BFW41_09175	COG2814	Major facilitator Superfamily
BFW41_09195	COG0672	)-iron permease
BFW41_09225	COG0659	secondary active sulfate transmembrane transporter activity
BFW41_09245	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
BFW41_09250	COG0840	transmembrane signaling receptor activity
BFW41_09260	COG2201	protein-glutamate methylesterase activity
BFW41_09270	COG0835	chemotaxis
BFW41_09275	COG0840	transmembrane signaling receptor activity
BFW41_09275	COG3290	protein histidine kinase activity
BFW41_09280	COG0643	Histidine kinase
BFW41_09280	COG2198	Histidine kinase
BFW41_09290	COG0745	RESPONSE REGULATOR receiver
BFW41_09295	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
BFW41_09300	COG0437	4 iron, 4 sulfur cluster binding
BFW41_09305	COG5557	Pfam Polysulphide reductase, NrfD
BFW41_09310	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
BFW41_09315	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
BFW41_09320	COG1773	rubredoxin
BFW41_09335	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BFW41_09340	COG0444	Belongs to the ABC transporter superfamily
BFW41_09345	COG3842	ATPase activity
BFW41_09350	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
BFW41_09355	COG0375	protein maturation
BFW41_09360	COG0309	Hydrogenase expression formation protein (HypE)
BFW41_09370	COG0298	carbon dioxide binding
BFW41_09375	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
BFW41_09385	COG1921	L-seryl-tRNASec selenium transferase activity
BFW41_09390	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
BFW41_09400	COG3260	NADH ubiquinone oxidoreductase 20
BFW41_09405	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BFW41_09410	COG3261	NADH dehydrogenase
BFW41_09410	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
BFW41_09415	COG0650	Formate hydrogenlyase subunit 4
BFW41_09420	COG0651	ATP synthesis coupled electron transport
BFW41_09425	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
BFW41_09430	COG3158	transport of potassium into the cell
BFW41_09435	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
BFW41_09440	COG3383	formate dehydrogenase (NAD+) activity
BFW41_09445	COG3383	formate dehydrogenase (NAD+) activity
BFW41_09465	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
BFW41_09470	COG0326	Molecular chaperone. Has ATPase activity
BFW41_09475	COG0563	adenylate kinase activity
BFW41_09480	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
BFW41_09490	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BFW41_09505	COG5001	Diguanylate cyclase
BFW41_09505	COG3300	MHYT domain
BFW41_09510	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
BFW41_09530	COG1021	2,3-dihydroxybenzoate-AMP ligase
BFW41_09535	COG1535	isochorismatase
BFW41_09535	COG3433	isochorismatase activity
BFW41_09540	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BFW41_09545	COG1028	Short-chain dehydrogenase reductase Sdr
BFW41_09555	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BFW41_09560	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BFW41_09570	COG1120	ATPase activity
BFW41_09575	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BFW41_09580	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BFW41_09585	COG4771	TonB-dependent receptor
BFW41_09605	COG0598	Magnesium transport protein CorA
BFW41_09625	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
BFW41_09630	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
BFW41_09635	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
BFW41_09650	COG1570	exodeoxyribonuclease VII activity
BFW41_09655	COG0697	spore germination
BFW41_09675	COG3158	transport of potassium into the cell
BFW41_09680	COG0516	GMP reductase activity
BFW41_09680	COG0517	IMP dehydrogenase activity
BFW41_09685	COG0519	Catalyzes the synthesis of GMP from XMP
BFW41_09685	COG0518	GMP synthase (glutamine-hydrolyzing) activity
BFW41_09690	COG0582	viral genome integration into host DNA
BFW41_09775	COG0789	Transcriptional regulator
BFW41_09825	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
BFW41_09840	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
BFW41_09870	COG0500	methyltransferase
BFW41_09880	COG2062	phosphohistidine phosphatase, SixA
BFW41_09890	COG0697	spore germination
BFW41_09895	COG4166	transmembrane transport
BFW41_09900	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
BFW41_09905	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
BFW41_09915	COG4591	ABC-type transport system involved in lipoprotein release permease component
BFW41_09920	COG1136	(ABC) transporter
BFW41_09925	COG4591	ABC-type transport system involved in lipoprotein release permease component
BFW41_09930	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
BFW41_09945	COG0544	peptidyl-prolyl cis-trans isomerase activity
BFW41_09950	COG0740	serine-type endopeptidase activity
BFW41_09955	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
BFW41_09960	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
BFW41_09970	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BFW41_09975	COG0488	(ABC) transporter
BFW41_09980	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BFW41_09985	COG3162	membrane
BFW41_10000	COG1024	Enoyl-CoA hydratase
BFW41_10020	COG1115	amino acid carrier protein
BFW41_10035	COG1584	GPR1 FUN34 yaaH family protein
BFW41_10070	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
BFW41_10075	COG1960	acyl-CoA dehydrogenase activity
BFW41_10085	COG1960	acyl-CoA dehydrogenase activity
BFW41_10090	COG1024	Enoyl-CoA hydratase
BFW41_10095	COG1024	Enoyl-CoA hydratase
BFW41_10105	COG1028	Short-chain dehydrogenase reductase Sdr
BFW41_10115	COG0730	response to heat
BFW41_10135	COG3300	MHYT domain
BFW41_10135	COG5001	Diguanylate cyclase
BFW41_10140	COG0583	DNA-binding transcription factor activity
BFW41_10145	COG2723	6-phospho-beta-galactosidase activity
BFW41_10150	COG5001	Diguanylate cyclase
BFW41_10150	COG3300	MHYT domain
BFW41_10160	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
BFW41_10170	COG0583	DNA-binding transcription factor activity
BFW41_10175	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
BFW41_10180	COG0673	inositol 2-dehydrogenase activity
BFW41_10185	COG0583	DNA-binding transcription factor activity
BFW41_10195	COG1560	Kdo2-lipid A biosynthetic process
BFW41_10200	COG1560	Kdo2-lipid A biosynthetic process
BFW41_10225	COG0417	DNA replication proofreading
BFW41_10255	COG0534	Mate efflux family protein
BFW41_10265	COG0307	riboflavin synthase, alpha
BFW41_10275	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BFW41_10280	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
BFW41_10285	COG0697	spore germination
BFW41_10290	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
BFW41_10330	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BFW41_10340	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
BFW41_10345	COG2894	cell division
BFW41_10350	COG0850	regulation of cytokinetic process
BFW41_10355	COG3100	YcgL domain-containing protein
BFW41_10360	COG2951	lytic endotransglycosylase activity
BFW41_10365	COG1760	l-serine dehydratase
BFW41_10370	COG1760	l-serine dehydratase
BFW41_10375	COG3123	guanosine phosphorylase activity
BFW41_10395	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
BFW41_10400	COG2067	long-chain fatty acid transport protein
BFW41_10415	COG1595	DNA-templated transcription, initiation
BFW41_10445	COG0714	Associated with various cellular activities
BFW41_10450	COG0183	Belongs to the thiolase family
BFW41_10455	COG1250	3-hydroxyacyl-CoA dehydrogenase
BFW41_10455	COG1024	Enoyl-CoA hydratase
BFW41_10465	COG4681	YaeQ
BFW41_10480	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
BFW41_10485	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
BFW41_10490	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BFW41_10500	COG0549	Belongs to the carbamate kinase family
BFW41_10505	COG0697	spore germination
BFW41_10510	COG3608	succinylglutamate desuccinylase aspartoacylase
BFW41_10510	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
BFW41_10515	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
BFW41_10525	COG0493	'glutamate synthase
BFW41_10525	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
BFW41_10530	COG0402	S-adenosylhomocysteine deaminase activity
BFW41_10535	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
BFW41_10540	COG2080	2 iron, 2 sulfur cluster binding
BFW41_10540	COG1529	Aldehyde oxidase and xanthine dehydrogenase
BFW41_10545	COG2233	PERMEase
BFW41_10550	COG0402	S-adenosylhomocysteine deaminase activity
BFW41_10555	COG2252	PERMEase
BFW41_10560	COG1529	Aldehyde oxidase and xanthine dehydrogenase
BFW41_10565	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
BFW41_10570	COG2080	2 iron, 2 sulfur cluster binding
BFW41_10580	COG3134	Outer membrane lipoprotein
BFW41_10590	COG1288	antiporter activity
BFW41_10595	COG0318	PFAM AMP-dependent synthetase and ligase
BFW41_10605	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
BFW41_10605	COG0140	phosphoribosyl-ATP diphosphatase activity
BFW41_10610	COG0107	imidazoleglycerol-phosphate synthase activity
BFW41_10615	COG0784	Response regulator, receiver
BFW41_10615	COG2198	Histidine kinase
BFW41_10615	COG2205	protein histidine kinase activity
BFW41_10625	COG3437	response regulator, receiver
BFW41_10630	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
BFW41_10635	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
BFW41_10640	COG0131	Imidazoleglycerol-phosphate dehydratase
BFW41_10640	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
BFW41_10645	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
BFW41_10650	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
BFW41_10655	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
BFW41_10665	COG1199	ATP-dependent helicase activity
BFW41_10670	COG1214	PFAM Peptidase M22, glycoprotease
BFW41_10680	COG0596	Alpha beta hydrolase
BFW41_10680	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
BFW41_10680	COG2226	methyltransferase
BFW41_10685	COG0318	PFAM AMP-dependent synthetase and ligase
BFW41_10690	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
BFW41_10705	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
BFW41_10710	COG2832	Protein of unknown function (DUF454)
BFW41_10715	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
BFW41_10725	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
BFW41_10745	COG1643	Atp-dependent helicase
BFW41_10755	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
BFW41_10765	COG3437	response regulator, receiver
BFW41_10770	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BFW41_10775	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
BFW41_10780	COG0709	Synthesizes selenophosphate from selenide and ATP
BFW41_10795	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
BFW41_10800	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
BFW41_10810	COG1254	Belongs to the acylphosphatase family
BFW41_10815	COG0625	glutathione transferase activity
BFW41_10820	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BFW41_10820	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BFW41_10825	COG0489	protein tyrosine kinase activity
BFW41_10830	COG0572	uridine kinase
BFW41_10835	COG0717	Belongs to the dCTP deaminase family
BFW41_10840	COG0306	phosphate transporter
BFW41_10845	COG1530	ribonuclease E activity
BFW41_10850	COG0564	pseudouridine synthase activity
BFW41_10855	COG0546	phosphoglycolate phosphatase activity
BFW41_10860	COG0424	maF-like protein
BFW41_10865	COG2814	Major facilitator Superfamily
BFW41_10880	COG1399	metal-binding, possibly nucleic acid-binding protein
BFW41_10885	COG0333	Belongs to the bacterial ribosomal protein bL32 family
BFW41_10890	COG0416	fatty acid biosynthetic process
BFW41_10895	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BFW41_10905	COG1028	Short-chain dehydrogenase reductase Sdr
BFW41_10910	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BFW41_10915	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
BFW41_10920	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BFW41_10925	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
BFW41_10930	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
BFW41_10935	COG0470	DNA polymerase III
BFW41_10940	COG0084	hydrolase, TatD family'
BFW41_10955	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
BFW41_10955	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
BFW41_10960	COG3008	intermembrane lipid transfer
BFW41_10965	COG2995	paraquat-inducible protein a
BFW41_10975	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
BFW41_10980	COG0372	Belongs to the citrate synthase family
BFW41_11025	COG4221	oxidoreductase activity
BFW41_11035	COG3141	response to X-ray
BFW41_11045	COG1067	ATP-dependent peptidase activity
BFW41_11050	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
BFW41_11060	COG0488	(ABC) transporter
BFW41_11070	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
BFW41_11070	COG0116	Belongs to the methyltransferase superfamily
BFW41_11085	COG0167	dihydroorotate dehydrogenase activity
BFW41_11090	COG2902	Dehydrogenase
BFW41_11100	COG0308	aminopeptidase N
BFW41_11110	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
BFW41_11115	COG1956	GAF domain-containing protein
BFW41_11125	COG3278	Belongs to the heme-copper respiratory oxidase family
BFW41_11140	COG2010	Cytochrome c
BFW41_11165	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BFW41_11170	COG0589	response to stress
BFW41_11175	COG0037	tRNA processing
BFW41_11190	COG0625	glutathione transferase activity
BFW41_11195	COG1869	D-ribose catabolic process
BFW41_11200	COG1129	ABC transporter
BFW41_11205	COG1172	Belongs to the binding-protein-dependent transport system permease family
BFW41_11210	COG1879	ABC-type sugar transport system periplasmic component
BFW41_11215	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BFW41_11220	COG1609	Transcriptional regulator
BFW41_11225	COG3300	MHYT domain
BFW41_11225	COG5001	Diguanylate cyclase
BFW41_11235	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
BFW41_11250	COG0784	Response regulator, receiver
BFW41_11250	COG2205	protein histidine kinase activity
BFW41_11255	COG0776	regulation of translation
BFW41_11260	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BFW41_11260	COG0072	phenylalanine-tRNA ligase activity
BFW41_11265	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
BFW41_11270	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
BFW41_11275	COG0291	Belongs to the bacterial ribosomal protein bL35 family
BFW41_11280	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
BFW41_11285	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
BFW41_11305	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
BFW41_11315	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BFW41_11320	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BFW41_11325	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
BFW41_11330	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
BFW41_11335	COG3313	Fe-S protein
BFW41_11340	COG2942	2-epimerase
BFW41_11345	COG3716	PTS system mannose fructose sorbose family IID component
BFW41_11350	COG3715	PTS system
BFW41_11355	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
BFW41_11355	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BFW41_11370	COG1609	Transcriptional regulator
BFW41_11375	COG2140	Oxalate decarboxylase
BFW41_11380	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BFW41_11380	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BFW41_11380	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
BFW41_11385	COG1105	Belongs to the carbohydrate kinase PfkB family
BFW41_11390	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
BFW41_11390	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
BFW41_11395	COG1609	Transcriptional regulator
BFW41_11400	COG0814	amino acid
BFW41_11410	COG5654	RES domain protein
BFW41_11415	COG0513	Belongs to the DEAD box helicase family
BFW41_11425	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
BFW41_11430	COG2890	protein-(glutamine-N5) methyltransferase activity
BFW41_11435	COG2840	Smr protein MutS2
BFW41_11445	COG3706	GGDEF domain
BFW41_11475	COG2824	Alkylphosphonate utilization operon protein PhnA
BFW41_11485	COG0384	phenazine biosynthesis protein PhzF
BFW41_11515	COG0242	peptide deformylase activity
BFW41_11535	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
BFW41_11540	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
BFW41_11550	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
BFW41_11555	COG1434	Gram-negative-bacterium-type cell wall biogenesis
BFW41_11565	COG0205	6-phosphofructokinase activity
BFW41_11570	COG1473	amidohydrolase
BFW41_11575	COG1011	Hydrolase
BFW41_11580	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
BFW41_11635	COG3593	DNA synthesis involved in DNA repair
BFW41_11650	COG0583	DNA-binding transcription factor activity
BFW41_11655	COG0730	response to heat
BFW41_11670	COG1181	Belongs to the D-alanine--D-alanine ligase family
BFW41_11680	COG0386	Belongs to the glutathione peroxidase family
BFW41_11685	COG0513	Belongs to the DEAD box helicase family
BFW41_11690	COG0456	acetyltransferase
BFW41_11700	COG1742	UPF0060 membrane protein
BFW41_11730	COG2329	Antibiotic biosynthesis monooxygenase
BFW41_11735	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
BFW41_11765	COG2501	S4 domain
BFW41_11775	COG1132	(ABC) transporter
BFW41_11780	COG1132	(ABC) transporter
BFW41_11790	COG3118	belongs to the thioredoxin family
BFW41_11795	COG0471	metal ion transport
BFW41_11800	COG0058	SHG alpha-glucan phosphorylase activity
BFW41_11835	COG0814	amino acid
BFW41_11845	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
BFW41_11850	COG0514	ATP-dependent DNA helicase (RecQ)
BFW41_11855	COG2766	serine protein kinase
BFW41_11865	COG2719	SpoVR family
BFW41_11870	COG2186	Transcriptional regulator
BFW41_11875	COG3067	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
BFW41_11880	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
BFW41_11885	COG0586	Pfam SNARE associated Golgi protein
BFW41_11895	COG0556	nucleotide-excision repair
BFW41_11905	COG0569	domain protein
BFW41_11905	COG2985	domain, Protein
BFW41_11910	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
BFW41_11930	COG4565	transcriptional regulatory protein
BFW41_11935	COG3290	protein histidine kinase activity
BFW41_11940	COG1940	carbohydrate kinase activity
BFW41_11940	COG1846	Transcriptional regulator
BFW41_11945	COG0840	transmembrane signaling receptor activity
BFW41_11950	COG3012	SEC-C Motif Domain Protein
BFW41_11955	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
BFW41_11960	COG3075	Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses fumarate or nitrate as electron acceptor
BFW41_11965	COG0247	lactate metabolic process
BFW41_11980	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
BFW41_11985	COG0437	4 iron, 4 sulfur cluster binding
BFW41_11990	COG3301	Polysulphide reductase, NrfD
BFW41_11995	COG1138	Cytochrome C-type biogenesis protein
BFW41_12000	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BFW41_12005	COG4235	cytochrome complex assembly
BFW41_12005	COG3088	subunit of a heme lyase
BFW41_12010	COG1051	belongs to the nudix hydrolase family
BFW41_12020	COG3033	Beta-eliminating lyase
BFW41_12025	COG3046	protein related to deoxyribodipyrimidine photolyase
BFW41_12030	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BFW41_12060	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
BFW41_12065	COG0583	DNA-binding transcription factor activity
BFW41_12075	COG4774	siderophore transport
BFW41_12080	COG4977	sequence-specific DNA binding
BFW41_12090	COG0583	DNA-binding transcription factor activity
BFW41_12095	COG2910	NAD(P)H-binding
BFW41_12105	COG0626	cystathionine gamma-synthase activity
BFW41_12110	COG0612	Peptidase, M16
BFW41_12115	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
BFW41_12120	COG2076	Multidrug Resistance protein
BFW41_12125	COG1944	ATP diphosphatase activity
BFW41_12130	COG2116	formate transmembrane transporter activity
BFW41_12135	COG1882	Formate acetyltransferase
BFW41_12140	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BFW41_12150	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
BFW41_12160	COG1840	ABC-type Fe3 transport system, periplasmic component
BFW41_12165	COG3842	ATPase activity
BFW41_12175	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BFW41_12180	COG2983	Belongs to the UPF0260 family
BFW41_12190	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
BFW41_12195	COG0045	succinate-CoA ligase (ADP-forming) activity
BFW41_12200	COG0508	dehydrogenase complex catalyzes the overall conversion of
BFW41_12205	COG0567	Dehydrogenase, E1 component
BFW41_12215	COG1053	succinate dehydrogenase
BFW41_12220	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
BFW41_12225	COG2009	succinate dehydrogenase
BFW41_12245	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
BFW41_12250	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
BFW41_12250	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BFW41_12260	COG3069	C4-dicarboxylate transmembrane transporter activity
BFW41_12275	COG1451	nucleotide metabolic process
BFW41_12290	COG0254	rRNA binding
BFW41_12295	COG0257	Belongs to the bacterial ribosomal protein bL36 family
BFW41_12305	COG0583	DNA-binding transcription factor activity
BFW41_12315	COG1172	Belongs to the binding-protein-dependent transport system permease family
BFW41_12325	COG1879	ABC-type sugar transport system periplasmic component
BFW41_12330	COG1069	ribulokinase activity
BFW41_12340	COG2160	L-arabinose isomerase activity
BFW41_12355	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BFW41_12355	COG1263	PTS System
BFW41_12360	COG1874	Beta-galactosidase
BFW41_12365	COG3867	Arabinogalactan endo-beta-1,4-galactanase
BFW41_12370	COG3833	ABC-type maltose transport systems, permease component
BFW41_12375	COG1175	transmembrane transport
BFW41_12380	COG2182	Extracellular solute-binding protein
BFW41_12405	COG4580	involved in the transport of maltose and maltodextrins
BFW41_12410	COG1609	Transcriptional regulator
BFW41_12415	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
BFW41_12420	COG1085	galactose-1-phosphate uridylyltransferase
BFW41_12425	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
BFW41_12445	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
BFW41_12490	COG2925	Exonuclease
BFW41_12500	COG3345	alpha-galactosidase
BFW41_12505	COG1380	Effector of murein hydrolase LrgA
BFW41_12510	COG1346	cytolysis
BFW41_12515	COG0295	cytidine deaminase activity
BFW41_12520	COG1022	Amp-dependent synthetase and ligase
BFW41_12535	COG0861	Integral membrane protein TerC family
BFW41_12540	COG2885	chlorophyll binding
BFW41_12545	COG2199	diguanylate cyclase activity
BFW41_12560	COG2154	pterin-4-alpha-carbinolamine dehydratase
BFW41_12565	COG2154	pterin-4-alpha-carbinolamine dehydratase
BFW41_12575	COG3768	UPF0283 membrane protein
BFW41_12580	COG3106	COG3106 Predicted ATPase
BFW41_12595	COG1842	Phage shock protein A
BFW41_12600	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
BFW41_12610	COG4168	peptide transport system, permease
BFW41_12615	COG4171	peptide transport system, permease
BFW41_12625	COG4172	Belongs to the ABC transporter superfamily
BFW41_12635	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
BFW41_12640	COG1286	toxin biosynthetic process
BFW41_12645	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
BFW41_12655	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
BFW41_12660	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
BFW41_12665	COG1674	ftsk spoiiie
BFW41_12665	COG0531	amino acid
BFW41_12675	COG0492	ferredoxin-NADP+ reductase activity
BFW41_12680	COG3706	GGDEF domain
BFW41_12685	COG3134	Outer membrane lipoprotein
BFW41_12690	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
BFW41_12695	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
BFW41_12700	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
BFW41_12705	COG0542	response to heat
BFW41_12710	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
BFW41_12715	COG1278	Cold shock
BFW41_12720	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
BFW41_12740	COG4193	domain, Protein
BFW41_12740	COG5632	N-Acetylmuramoyl-L-alanine amidase
BFW41_12740	COG3266	domain, Protein
BFW41_12745	COG3501	Rhs element vgr protein
BFW41_12850	COG3501	Rhs element vgr protein
BFW41_12875	COG1435	thymidine kinase activity
BFW41_12880	COG1757	Na H antiporter
BFW41_12885	COG2916	Histone family protein nucleoid-structuring protein H-NS
BFW41_12890	COG2096	Adenosyltransferase
BFW41_12895	COG3530	Putative quorum-sensing-regulated virulence factor
BFW41_12900	COG0602	queuosine metabolic process
BFW41_12905	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
BFW41_12925	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
BFW41_12935	COG0776	regulation of translation
BFW41_12940	COG0539	negative regulation of cytoplasmic translation
BFW41_12945	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
BFW41_12955	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
BFW41_12965	COG0583	DNA-binding transcription factor activity
BFW41_12990	COG5001	Diguanylate cyclase
BFW41_12990	COG3300	MHYT domain
BFW41_13000	COG0583	DNA-binding transcription factor activity
BFW41_13005	COG3437	response regulator, receiver
BFW41_13030	COG4989	oxidoreductase activity
BFW41_13035	COG0724	RNA recognition motif
BFW41_13055	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
BFW41_13070	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
BFW41_13075	COG1360	Flagellar Motor Protein
BFW41_13080	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BFW41_13085	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BFW41_13090	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BFW41_13090	COG0649	NAD binding
BFW41_13105	COG1034	ATP synthesis coupled electron transport
BFW41_13110	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
BFW41_13115	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BFW41_13120	COG0839	Belongs to the complex I subunit 6 family
BFW41_13125	COG0713	ATP synthesis coupled electron transport
BFW41_13135	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BFW41_13140	COG1007	ATP synthesis coupled electron transport
BFW41_13155	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
BFW41_13155	COG2199	diguanylate cyclase activity
BFW41_13160	COG0047	phosphoribosylformylglycinamidine synthase activity
BFW41_13160	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
BFW41_13165	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
BFW41_13175	COG1645	bacterial-type flagellum-dependent swarming motility
BFW41_13180	COG1160	GTP binding
BFW41_13185	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BFW41_13190	COG2976	Protein conserved in bacteria
BFW41_13195	COG0124	histidyl-tRNA synthetase
BFW41_13200	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
BFW41_13215	COG0820	rRNA (adenine-C2-)-methyltransferase activity
BFW41_13220	COG0105	UTP biosynthetic process
BFW41_13225	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
BFW41_13235	COG0633	Ferredoxin
BFW41_13240	COG0443	Heat shock 70 kDa protein
BFW41_13245	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
BFW41_13255	COG0822	iron-sulfur transferase activity
BFW41_13260	COG1104	cysteine desulfurase activity
BFW41_13305	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BFW41_13310	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BFW41_13315	COG1862	Preprotein translocase
BFW41_13320	COG0343	queuine tRNA-ribosyltransferase activity
BFW41_13325	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
BFW41_13330	COG0517	IMP dehydrogenase activity
BFW41_13335	COG0450	alkyl hydroperoxide reductase
BFW41_13340	COG3634	alkyl hydroperoxide reductase activity
BFW41_13360	COG1393	Belongs to the ArsC family
BFW41_13365	COG0798	PFAM Bile acid sodium symporter
BFW41_13470	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
BFW41_13470	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
BFW41_13475	COG0509	glycine decarboxylation via glycine cleavage system
BFW41_13480	COG0404	The glycine cleavage system catalyzes the degradation of glycine
BFW41_13485	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BFW41_13490	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BFW41_13510	COG2814	Major facilitator Superfamily
BFW41_13515	COG0625	glutathione transferase activity
BFW41_13525	COG0483	inositol monophosphate 1-phosphatase activity
BFW41_13550	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
BFW41_13590	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
BFW41_13595	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
BFW41_13610	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BFW41_13610	COG0301	tRNA thio-modification
BFW41_13620	COG4953	penicillin-binding protein 1C
BFW41_13625	COG2373	Large extracellular alpha-helical protein
BFW41_13630	COG0446	pyridine nucleotide-disulphide oxidoreductase
BFW41_13640	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
BFW41_13675	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
BFW41_13685	COG1216	Glycosyl transferase, family 2
BFW41_13705	COG4215	(ABC) transporter
BFW41_13710	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BFW41_13720	COG2431	L-lysine efflux transmembrane transporter activity
BFW41_13725	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
BFW41_13730	COG3124	Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP
BFW41_13745	COG1393	Belongs to the ArsC family
BFW41_13755	COG4783	chaperone-mediated protein folding
BFW41_13760	COG0425	Belongs to the sulfur carrier protein TusA family
BFW41_13785	COG3842	ATPase activity
BFW41_13795	COG1175	transmembrane transport
BFW41_13805	COG3081	Nucleoid-associated protein
BFW41_13810	COG3082	Protein of unknown function (DUF1414)
BFW41_13815	COG3083	sulfuric ester hydrolase activity
BFW41_13825	COG4771	TonB-dependent receptor
BFW41_13830	COG1770	oligopeptidase
BFW41_13850	COG4574	serine-type endopeptidase inhibitor activity
BFW41_13855	COG3085	chromosome segregation
BFW41_13860	COG0583	DNA-binding transcription factor activity
BFW41_13865	COG0287	Prephenate dehydrogenase
BFW41_13865	COG1605	Chorismate mutase
BFW41_13870	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
BFW41_13875	COG0584	glycerophosphoryl diester phosphodiesterase
BFW41_13885	COG1349	DNA-binding transcription factor activity
BFW41_13890	COG2271	Major facilitator Superfamily
BFW41_13895	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
BFW41_13900	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
BFW41_13905	COG0583	DNA-binding transcription factor activity
BFW41_13930	COG0656	L-ascorbic acid biosynthetic process
BFW41_13935	COG2814	Major facilitator Superfamily
BFW41_13945	COG1294	oxidase, subunit
BFW41_13955	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BFW41_13965	COG2979	Protein of unknown function (DUF533)
BFW41_13980	COG1607	acyl-coa hydrolase
BFW41_13995	COG2271	Major facilitator Superfamily
BFW41_14000	COG0583	DNA-binding transcription factor activity
BFW41_14010	COG2807	transmembrane transport
BFW41_14020	COG1187	pseudouridine synthase activity
BFW41_14035	COG0346	lactoylglutathione lyase activity
BFW41_14045	COG1403	HNH endonuclease
BFW41_14055	COG2964	Protein conserved in bacteria
BFW41_14060	COG3681	Belongs to the UPF0597 family
BFW41_14070	COG0814	amino acid
BFW41_14090	COG1166	arginine decarboxylase activity
BFW41_14100	COG2195	Cleaves the N-terminal amino acid of tripeptides
BFW41_14130	COG0583	DNA-binding transcription factor activity
BFW41_14140	COG2759	Belongs to the formate--tetrahydrofolate ligase family
BFW41_14145	COG0840	transmembrane signaling receptor activity
BFW41_14150	COG0302	gtp cyclohydrolase
BFW41_14160	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
BFW41_14165	COG2267	carboxylic ester hydrolase activity
BFW41_14170	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
BFW41_14185	COG0314	molybdopterin synthase activity
BFW41_14190	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
BFW41_14195	COG0315	cyclic pyranopterin monophosphate synthase activity
BFW41_14200	COG0521	Mo-molybdopterin cofactor biosynthetic process
BFW41_14205	COG3005	denitrification pathway
BFW41_14215	COG0348	domain, Protein
BFW41_14220	COG0437	4 iron, 4 sulfur cluster binding
BFW41_14225	COG0243	molybdopterin cofactor binding
BFW41_14235	COG1149	4fe-4S ferredoxin, iron-sulfur binding domain protein
BFW41_14235	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
BFW41_14240	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
BFW41_14245	COG3850	Histidine kinase
BFW41_14250	COG2197	response regulator
BFW41_14280	COG0121	glutamine amidotransferase
BFW41_14285	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
BFW41_14290	COG1960	acyl-CoA dehydrogenase activity
BFW41_14295	COG3437	response regulator, receiver
BFW41_14295	COG0784	Response regulator, receiver
BFW41_14305	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
BFW41_14310	COG0328	RNA-DNA hybrid ribonuclease activity
BFW41_14315	COG2226	methyltransferase
BFW41_14320	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BFW41_14325	COG0741	lytic transglycosylase activity
BFW41_14325	COG1388	LysM domain
BFW41_14330	COG3021	interspecies interaction between organisms
BFW41_14340	COG1607	acyl-coa hydrolase
BFW41_14355	COG0741	lytic transglycosylase activity
BFW41_14365	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
BFW41_14385	COG2911	Protein conserved in bacteria
BFW41_14390	COG0729	surface antigen
BFW41_14400	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BFW41_14405	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BFW41_14415	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
BFW41_14425	COG4134	Bacterial extracellular solute-binding protein
BFW41_14435	COG4136	ATPase activity
BFW41_14440	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
BFW41_14445	COG2951	lytic endotransglycosylase activity
BFW41_14460	COG1846	Transcriptional regulator
BFW41_14470	COG0033	Phosphoglucomutase
BFW41_14475	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
BFW41_14480	COG0596	Alpha beta hydrolase
BFW41_14495	COG0716	FMN binding
BFW41_14505	COG0735	belongs to the Fur family
BFW41_14510	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
BFW41_14520	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BFW41_14520	COG1263	PTS System
BFW41_14520	COG2190	(PTS) system
BFW41_14525	COG0363	glucosamine-6-phosphate deaminase activity
BFW41_14530	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
BFW41_14535	COG1940	carbohydrate kinase activity
BFW41_14535	COG1846	Transcriptional regulator
BFW41_14540	COG2194	sulfuric ester hydrolase activity
BFW41_14545	COG0217	transcriptional regulatory protein
BFW41_14550	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
BFW41_14555	COG1801	Protein of unknown function DUF72
BFW41_14560	COG4106	trans-aconitate 2-methyltransferase activity
BFW41_14565	COG0500	methyltransferase
BFW41_14585	COG0450	alkyl hydroperoxide reductase
BFW41_14590	COG0583	DNA-binding transcription factor activity
BFW41_14600	COG0791	NLP P60 protein
BFW41_14615	COG1309	transcriptional regulator
BFW41_14655	COG0534	Mate efflux family protein
BFW41_14670	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
BFW41_14670	COG1013	pyruvate-flavodoxin oxidoreductase activity
BFW41_14670	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
BFW41_14670	COG0674	pyruvate-flavodoxin oxidoreductase activity
BFW41_14680	COG3217	Mosc domain protein beta barrel domain protein
BFW41_14680	COG0633	Ferredoxin
BFW41_14680	COG3217	Mosc domain protein beta barrel domain protein
BFW41_14680	COG0633	Ferredoxin
BFW41_14690	COG0501	Belongs to the peptidase M48B family
BFW41_14695	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
BFW41_14700	COG1073	alpha beta
BFW41_14700	COG2226	methyltransferase
BFW41_14705	COG0156	8-amino-7-oxononanoate synthase activity
BFW41_14710	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
BFW41_14730	COG0017	Asparaginyl-tRNA synthetase
BFW41_14735	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
BFW41_14750	COG3069	C4-dicarboxylate transmembrane transporter activity
BFW41_14760	COG0583	DNA-binding transcription factor activity
BFW41_14765	COG1393	Belongs to the ArsC family
BFW41_14770	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BFW41_14775	COG1876	peptidase activity
BFW41_14780	COG3263	regulation of cellular component size
BFW41_14790	COG3263	regulation of cellular component size
BFW41_14800	COG1280	lysine exporter protein (LysE YggA)
BFW41_14825	COG1957	nucleoside hydrolase
BFW41_14830	COG0564	pseudouridine synthase activity
BFW41_14840	COG1454	alcohol dehydrogenase
BFW41_14845	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BFW41_14860	COG2867	negative regulation of translational initiation
BFW41_14865	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
BFW41_14875	COG0582	viral genome integration into host DNA
BFW41_14910	COG5377	YqaJ viral recombinase family
BFW41_14930	COG2003	Belongs to the UPF0758 family
BFW41_14960	COG2963	transposase activity
BFW41_14975	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
BFW41_15005	COG2814	Major facilitator Superfamily
BFW41_15005	COG0477	Major facilitator Superfamily
BFW41_15010	COG0457	Tetratricopeptide repeat
BFW41_15015	COG1940	carbohydrate kinase activity
BFW41_15020	COG0583	DNA-binding transcription factor activity
BFW41_15025	COG3048	D-serine ammonia-lyase activity
BFW41_15035	COG0538	isocitrate dehydrogenase activity
BFW41_15040	COG2207	Transcriptional regulator
BFW41_15055	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BFW41_15070	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
BFW41_15075	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BFW41_15075	COG1263	PTS System
BFW41_15080	COG1609	Transcriptional regulator
BFW41_15090	COG0789	Transcriptional regulator
BFW41_15100	COG0456	acetyltransferase
BFW41_15110	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BFW41_15110	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BFW41_15110	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BFW41_15120	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BFW41_15130	COG1187	pseudouridine synthase activity
BFW41_15140	COG0482	sulfurtransferase activity
BFW41_15145	COG2915	High frequency lysogenization protein hflD homolog
BFW41_15150	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
BFW41_15155	COG2850	peptidyl-arginine hydroxylation
BFW41_15165	COG3153	acetyltransferase
BFW41_15175	COG0625	glutathione transferase activity
BFW41_15180	COG0259	pyridoxamine-phosphate oxidase activity
BFW41_15195	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
BFW41_15195	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
BFW41_15200	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
BFW41_15215	COG3088	subunit of a heme lyase
BFW41_15215	COG4235	cytochrome complex assembly
BFW41_15220	COG3088	subunit of a heme lyase
BFW41_15220	COG4235	cytochrome complex assembly
BFW41_15225	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BFW41_15230	COG1138	Cytochrome C-type biogenesis protein
BFW41_15235	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
BFW41_15240	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
BFW41_15245	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
BFW41_15250	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
BFW41_15265	COG0835	chemotaxis
BFW41_15275	COG1192	Involved in chromosome partitioning
BFW41_15280	COG1360	Flagellar Motor Protein
BFW41_15285	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
BFW41_15290	COG2201	protein-glutamate methylesterase activity
BFW41_15295	COG0643	Histidine kinase
BFW41_15295	COG2198	Histidine kinase
BFW41_15300	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
BFW41_15315	COG0455	bacterial-type flagellum organization
BFW41_15325	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
BFW41_15335	COG1684	flagellar biosynthetic protein fliR
BFW41_15340	COG1987	bacterial-type flagellum assembly
BFW41_15390	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
BFW41_15400	COG1677	Flagellar hook-basal body complex protein FliE
BFW41_15420	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
BFW41_15430	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
BFW41_15430	COG3064	Membrane
BFW41_15430	COG1073	alpha beta
BFW41_15445	COG2274	protein secretion by the type I secretion system
BFW41_15455	COG2274	protein secretion by the type I secretion system
BFW41_15460	COG0745	RESPONSE REGULATOR receiver
BFW41_15475	COG1737	Transcriptional regulator
BFW41_15480	COG0469	pyruvate kinase activity
BFW41_15490	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BFW41_15495	COG1960	acyl-CoA dehydrogenase activity
BFW41_15505	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
BFW41_15515	COG0243	molybdopterin cofactor binding
BFW41_15520	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
BFW41_15525	COG0583	DNA-binding transcription factor activity
BFW41_15545	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
BFW41_15550	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
BFW41_15555	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
BFW41_15560	COG1454	alcohol dehydrogenase
BFW41_15560	COG1012	belongs to the aldehyde dehydrogenase family
BFW41_15570	COG1012	belongs to the aldehyde dehydrogenase family
BFW41_15570	COG1454	alcohol dehydrogenase
BFW41_15575	COG1882	Formate acetyltransferase
BFW41_15580	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
BFW41_15585	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
BFW41_15590	COG4869	propanediol catabolic process
BFW41_15610	COG0582	viral genome integration into host DNA
BFW41_15620	COG3311	Transcriptional regulator
BFW41_15665	COG2003	Belongs to the UPF0758 family
BFW41_15700	COG1518	maintenance of DNA repeat elements
BFW41_15705	COG1203	CRISPR-associated helicase, Cas3
BFW41_15730	COG3316	Transposase and inactivated derivatives
BFW41_15770	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
BFW41_15790	COG0583	DNA-binding transcription factor activity
BFW41_15810	COG3316	Transposase and inactivated derivatives
BFW41_15880	COG1388	LysM domain
BFW41_15880	COG1376	ErfK ybiS ycfS ynhG family protein
BFW41_15900	COG3129	Specifically methylates the adenine in position 1618 of 23S rRNA
BFW41_15905	COG0791	NLP P60 protein
BFW41_15915	COG3118	belongs to the thioredoxin family
BFW41_15925	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
BFW41_15930	COG0788	formyltetrahydrofolate deformylase activity
BFW41_15940	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BFW41_15960	COG0366	Alpha amylase catalytic
BFW41_15965	COG0741	lytic transglycosylase activity
BFW41_15965	COG1196	nuclear chromosome segregation
BFW41_15965	COG0739	heme binding
BFW41_15970	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
BFW41_15975	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
BFW41_15985	COG0673	inositol 2-dehydrogenase activity
BFW41_16005	COG1032	radical SAM domain protein
BFW41_16015	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BFW41_16020	COG1566	PFAM secretion protein HlyD family protein
BFW41_16025	COG2199	diguanylate cyclase activity
BFW41_16025	COG2203	Gaf domain
BFW41_16030	COG1752	Esterase of the alpha-beta hydrolase superfamily
BFW41_16035	COG0733	neurotransmitter:sodium symporter activity
BFW41_16065	COG0281	malic enzyme
BFW41_16075	COG0534	Mate efflux family protein
BFW41_16085	COG0745	RESPONSE REGULATOR receiver
BFW41_16085	COG3706	GGDEF domain
BFW41_16090	COG2233	PERMEase
BFW41_16095	COG0095	Lipoate-protein ligase
BFW41_16100	COG1115	amino acid carrier protein
BFW41_16105	COG0019	diaminopimelate decarboxylase activity
BFW41_16125	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
BFW41_16145	COG1131	(ABC) transporter
BFW41_16150	COG0545	Peptidyl-prolyl cis-trans isomerase
BFW41_16155	COG3142	Participates in the control of copper homeostasis
BFW41_16170	COG4783	chaperone-mediated protein folding
BFW41_16180	COG5002	protein histidine kinase activity
BFW41_16185	COG0745	RESPONSE REGULATOR receiver
BFW41_16190	COG0346	lactoylglutathione lyase activity
BFW41_16195	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BFW41_16200	COG1960	acyl-CoA dehydrogenase activity
BFW41_16205	COG3284	Transcriptional regulator
BFW41_16210	COG1012	belongs to the aldehyde dehydrogenase family
BFW41_16220	COG0697	spore germination
BFW41_16225	COG4565	transcriptional regulatory protein
BFW41_16230	COG3290	protein histidine kinase activity
BFW41_16245	COG1846	Transcriptional regulator
BFW41_16250	COG1566	PFAM secretion protein HlyD family protein
BFW41_16280	COG0602	queuosine metabolic process
BFW41_16285	COG1328	CTP reductase activity
BFW41_16295	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
BFW41_16300	COG3115	cell septum assembly
BFW41_16305	COG1196	nuclear chromosome segregation
BFW41_16315	COG2860	membrane
BFW41_16325	COG3108	Peptidase M15
BFW41_16330	COG2989	Protein conserved in bacteria
BFW41_16345	COG0463	Glycosyl transferase, family 2
BFW41_16360	COG0366	Alpha amylase catalytic
BFW41_16395	COG3706	GGDEF domain
BFW41_16405	COG3590	peptidase
BFW41_16415	COG0488	(ABC) transporter
BFW41_16425	COG0531	amino acid
BFW41_16435	COG1073	alpha beta
BFW41_16440	COG1073	alpha beta
BFW41_16455	COG0814	amino acid
BFW41_16470	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
BFW41_16475	COG1982	Orn Lys Arg decarboxylase major
BFW41_16480	COG0531	amino acid
BFW41_16490	COG3710	Transcriptional regulator
BFW41_16495	COG0825	malonyl-CoA metabolic process
BFW41_16505	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
BFW41_16510	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
BFW41_16515	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
BFW41_16520	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
BFW41_16525	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
BFW41_16540	COG0750	zinc metalloprotease
BFW41_16545	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
BFW41_16550	COG0575	Belongs to the CDS family
BFW41_16560	COG0233	cytoplasmic translational termination
BFW41_16565	COG0528	UMP kinase activity
BFW41_16570	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
BFW41_16575	COG0052	Belongs to the universal ribosomal protein uS2 family
BFW41_16580	COG0024	Methionine aminopeptidase
BFW41_16585	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
BFW41_16590	COG2171	N-acyltransferase activity
BFW41_16600	COG1263	PTS System
BFW41_16600	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BFW41_16610	COG4580	involved in the transport of maltose and maltodextrins
BFW41_16620	COG0564	pseudouridine synthase activity
BFW41_16625	COG3098	single-species biofilm formation
BFW41_16650	COG5595	Zn-ribbon-containing, possibly nucleic-acid-binding protein (DUF2310)
BFW41_16660	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
BFW41_16660	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
BFW41_16670	COG3706	GGDEF domain
BFW41_16675	COG1611	Belongs to the LOG family
BFW41_16680	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BFW41_16685	COG0473	3-isopropylmalate dehydrogenase activity
BFW41_16695	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
BFW41_16700	COG2363	Small membrane protein
BFW41_16710	COG0583	DNA-binding transcription factor activity
BFW41_16715	COG0840	transmembrane signaling receptor activity
BFW41_16720	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
BFW41_16735	COG1477	protein flavinylation
BFW41_16740	COG2871	sodium ion transport
BFW41_16745	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
BFW41_16750	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
BFW41_16755	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
BFW41_16760	COG1805	sodium ion transport
BFW41_16765	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
BFW41_16770	COG0271	Belongs to the BolA IbaG family
BFW41_16775	COG2813	Specifically methylates the guanine in position
BFW41_16785	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
BFW41_16795	COG2211	Major facilitator Superfamily
BFW41_16800	COG3248	Nucleoside-binding outer membrane protein
BFW41_16805	COG1666	GTP binding
BFW41_16810	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
BFW41_16815	COG0693	protein deglycase activity
BFW41_16860	COG2771	luxR family
BFW41_16870	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
BFW41_16870	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
BFW41_16875	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
BFW41_16885	COG1151	hydroxylamine reductase activity
BFW41_16890	COG0783	Belongs to the Dps family
BFW41_16915	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
BFW41_16930	COG4221	oxidoreductase activity
BFW41_16940	COG0415	Belongs to the DNA photolyase family
BFW41_16945	COG0789	Transcriptional regulator
BFW41_16950	COG3272	Protein of unknown function (DUF1722)
BFW41_16980	COG0077	Prephenate dehydratase
BFW41_16980	COG1605	Chorismate mutase
BFW41_17005	COG3254	rhamnose metabolic process
BFW41_17015	COG4806	L-rhamnose isomerase
BFW41_17020	COG1070	Carbohydrate kinase
BFW41_17035	COG1454	alcohol dehydrogenase
BFW41_17040	COG0235	Class ii aldolase
BFW41_17050	COG0840	transmembrane signaling receptor activity
BFW41_17060	COG0300	oxidoreductase activity
BFW41_17085	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
BFW41_17110	COG0826	peptidase U32
BFW41_17115	COG1280	lysine exporter protein (LysE YggA)
BFW41_17130	COG0840	transmembrane signaling receptor activity
BFW41_17135	COG0745	RESPONSE REGULATOR receiver
BFW41_17145	COG0643	Histidine kinase
BFW41_17145	COG2198	Histidine kinase
BFW41_17155	COG0835	chemotaxis
BFW41_17160	COG0840	transmembrane signaling receptor activity
BFW41_17170	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
BFW41_17175	COG2201	protein-glutamate methylesterase activity
BFW41_17180	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
BFW41_17205	COG2199	diguanylate cyclase activity
BFW41_17205	COG2203	Gaf domain
BFW41_17205	COG2200	EAL domain
BFW41_17215	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
BFW41_17220	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
BFW41_17225	COG0305	Participates in initiation and elongation during chromosome replication
BFW41_17235	COG2200	EAL domain
BFW41_17240	COG0737	Belongs to the 5'-nucleotidase family
BFW41_17260	COG2204	response regulator
BFW41_17265	COG0545	Peptidyl-prolyl cis-trans isomerase
BFW41_17275	COG2900	Belongs to the SlyX family
BFW41_17280	COG1047	Peptidyl-prolyl cis-trans
BFW41_17285	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
BFW41_17295	COG0784	Response regulator, receiver
BFW41_17295	COG0835	chemotaxis
BFW41_17300	COG0429	hydrolase of the alpha beta-hydrolase fold
BFW41_17305	COG2203	Gaf domain
BFW41_17305	COG3706	GGDEF domain
BFW41_17305	COG5001	Diguanylate cyclase
BFW41_17305	COG4251	negative regulation of phosphorylation
BFW41_17310	COG3089	Belongs to the UPF0270 family
BFW41_17320	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
BFW41_17325	COG0463	Glycosyl transferase, family 2
BFW41_17330	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BFW41_17330	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
BFW41_17335	COG0726	polysaccharide deacetylase
BFW41_17340	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
BFW41_17345	COG2076	Multidrug Resistance protein
BFW41_17350	COG2076	Multidrug Resistance protein
BFW41_17355	COG3954	Phosphoribulokinase
BFW41_17370	COG1765	OsmC-like protein
BFW41_17375	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BFW41_17380	COG2226	methyltransferase
BFW41_17385	COG3397	chitin binding
BFW41_17400	COG2205	protein histidine kinase activity
BFW41_17400	COG2202	Pas domain
BFW41_17410	COG3655	Transcriptional regulator
BFW41_17415	COG2814	Major facilitator Superfamily
BFW41_17420	COG4771	TonB-dependent receptor
BFW41_17440	COG0748	coenzyme F420 binding
BFW41_17445	COG3721	Heme iron utilization protein
BFW41_17455	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BFW41_17480	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
BFW41_17485	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BFW41_17490	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
BFW41_17510	COG0741	lytic transglycosylase activity
BFW41_17515	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
BFW41_17530	COG0488	(ABC) transporter
BFW41_17540	COG2252	PERMEase
BFW41_17545	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
BFW41_17550	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
BFW41_17555	COG3178	'Phosphotransferase
BFW41_17560	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
BFW41_17570	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
BFW41_17575	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
BFW41_17585	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
BFW41_17595	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BFW41_17600	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
BFW41_17615	COG0318	PFAM AMP-dependent synthetase and ligase
BFW41_17630	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
BFW41_17635	COG0211	Belongs to the bacterial ribosomal protein bL27 family
BFW41_17645	COG0142	geranyltranstransferase activity
BFW41_17650	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
BFW41_17655	COG0330	HflC and HflK could
BFW41_17660	COG0330	HflC and HflK could
BFW41_17665	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
BFW41_17670	COG1923	regulation of RNA biosynthetic process
BFW41_17675	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
BFW41_17680	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
BFW41_17690	COG0802	atpase or kinase
BFW41_17695	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
BFW41_17695	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
BFW41_17720	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
BFW41_17725	COG2011	ABC-type metal ion transport system permease component
BFW41_17730	COG1464	Belongs to the NlpA lipoprotein family
BFW41_17740	COG0840	transmembrane signaling receptor activity
BFW41_17765	COG0784	Response regulator, receiver
BFW41_17765	COG2198	Histidine kinase
BFW41_17765	COG5002	protein histidine kinase activity
BFW41_17785	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
BFW41_17800	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
BFW41_17805	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
BFW41_17815	COG2716	regulation of RNA biosynthetic process
BFW41_17820	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
BFW41_17825	COG3013	Belongs to the UPF0304 family
BFW41_17830	COG3092	negative regulation of chromosome organization
BFW41_17835	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
BFW41_17840	COG0280	phosphate acetyltransferase
BFW41_17840	COG0857	belongs to the CobB CobQ family
BFW41_17850	COG0028	Belongs to the TPP enzyme family
BFW41_17860	COG0671	phosphoesterase, PA-phosphatase related
BFW41_17870	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
BFW41_17875	COG0473	3-isopropylmalate dehydrogenase activity
BFW41_17880	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
BFW41_17885	COG0066	3-isopropylmalate dehydratase activity
BFW41_17900	COG4143	(ABC) transporter
BFW41_17905	COG1178	ABC-type Fe3 transport system permease component
BFW41_17910	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
BFW41_17915	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
BFW41_17925	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BFW41_17955	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
BFW41_17960	COG0564	pseudouridine synthase activity
BFW41_17965	COG3300	MHYT domain
BFW41_17965	COG5001	Diguanylate cyclase
BFW41_17975	COG0459	protein refolding
BFW41_17980	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
BFW41_17985	COG0534	Mate efflux family protein
BFW41_17990	COG3030	protein affecting phage T7 exclusion by the F plasmid
BFW41_17995	COG1027	Aspartate ammonia-lyase
BFW41_18000	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
BFW41_18010	COG0477	Major facilitator Superfamily
BFW41_18025	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BFW41_18030	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BFW41_18040	COG0673	inositol 2-dehydrogenase activity
BFW41_18050	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
BFW41_18055	COG0635	Involved in the biosynthesis of porphyrin-containing compound
BFW41_18060	COG3036	rescue of stalled ribosome
BFW41_18065	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
BFW41_18075	COG0138	bifunctional purine biosynthesis protein purh
BFW41_18080	COG0151	Belongs to the GarS family
BFW41_18105	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
BFW41_18110	COG0358	DNA primase activity
BFW41_18115	COG1610	YqeY-like protein
BFW41_18120	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
BFW41_18130	COG4942	peptidase
BFW41_18130	COG1388	LysM domain
BFW41_18135	COG1238	metal cluster binding
BFW41_18140	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
BFW41_18145	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
BFW41_18150	COG0585	pseudouridine synthase activity
BFW41_18160	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
BFW41_18165	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
BFW41_18170	COG0148	phosphopyruvate hydratase activity
BFW41_18175	COG0504	CTP synthase activity
BFW41_18180	COG3956	TIGRFAM MazG family protein
BFW41_18185	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
BFW41_18190	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
BFW41_18200	COG4807	Protein conserved in bacteria
BFW41_18205	COG3023	N-Acetylmuramoyl-L-alanine amidase
BFW41_18210	COG1349	DNA-binding transcription factor activity
BFW41_18220	COG2222	sugar isomerase
BFW41_18225	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BFW41_18235	COG3716	PTS system mannose fructose sorbose family IID component
BFW41_18240	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
BFW41_18245	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
BFW41_18260	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
BFW41_18265	COG1381	Involved in DNA repair and RecF pathway recombination
BFW41_18275	COG0571	ribonuclease III activity
BFW41_18280	COG0681	Belongs to the peptidase S26 family
BFW41_18285	COG0481	GTPase activity
BFW41_18300	COG3073	An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E
BFW41_18305	COG1595	DNA-templated transcription, initiation
BFW41_18310	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
BFW41_18320	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
BFW41_18325	COG0354	folic acid binding
BFW41_18360	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BFW41_18370	COG0126	phosphoglycerate kinase activity
BFW41_18375	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
BFW41_18380	COG1940	carbohydrate kinase activity
BFW41_18385	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
BFW41_18400	COG4991	sh3 domain protein
BFW41_18405	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BFW41_18420	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
BFW41_18445	COG1505	serine-type exopeptidase activity
BFW41_18450	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
BFW41_18455	COG0765	amino acid transport
BFW41_18460	COG0765	amino acid transport
BFW41_18465	COG1126	abc transporter atp-binding protein
BFW41_18470	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BFW41_18475	COG0577	efflux transmembrane transporter activity
BFW41_18475	COG1136	(ABC) transporter
BFW41_18480	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BFW41_18485	COG0745	RESPONSE REGULATOR receiver
BFW41_18495	COG2816	NAD+ diphosphatase activity
BFW41_18535	COG2070	2-Nitropropane dioxygenase
BFW41_18565	COG1912	Pfam S-adenosyl-l-methionine hydroxide adenosyltransferase
BFW41_18585	COG0513	Belongs to the DEAD box helicase family
BFW41_18605	COG2957	Belongs to the agmatine deiminase family
BFW41_18615	COG2852	Protein conserved in bacteria
BFW41_18625	COG1902	pentaerythritol trinitrate reductase activity
BFW41_18655	COG3706	GGDEF domain
BFW41_18655	COG0745	RESPONSE REGULATOR receiver
BFW41_18660	COG3300	MHYT domain
BFW41_18660	COG5001	Diguanylate cyclase
BFW41_18670	COG0714	Associated with various cellular activities
BFW41_18680	COG0456	acetyltransferase
BFW41_18690	COG1022	Amp-dependent synthetase and ligase
BFW41_18695	COG2918	glutathione biosynthetic process
BFW41_18700	COG0612	Peptidase, M16
BFW41_18705	COG1238	metal cluster binding
BFW41_18725	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
BFW41_18730	COG0359	binds to the 23S rRNA
BFW41_18735	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
BFW41_18740	COG0360	Binds together with S18 to 16S ribosomal RNA
BFW41_18745	COG1914	H( )-stimulated, divalent metal cation uptake system
BFW41_18765	COG2153	protein acetylation
BFW41_18780	COG0557	exoribonuclease II activity
BFW41_18785	COG3706	GGDEF domain
BFW41_18790	COG1854	S-ribosylhomocysteine lyase activity
BFW41_18805	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
BFW41_18805	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BFW41_18865	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
BFW41_18870	COG1047	Peptidyl-prolyl cis-trans
BFW41_18875	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
BFW41_18880	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
BFW41_18885	COG0196	riboflavin kinase activity
BFW41_18890	COG0728	peptidoglycan biosynthetic process
BFW41_18895	COG0268	Binds directly to 16S ribosomal RNA
BFW41_18900	COG0640	Transcriptional regulator
BFW41_18905	COG0583	DNA-binding transcription factor activity
BFW41_18915	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
BFW41_18920	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
BFW41_18925	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
BFW41_18935	COG1051	belongs to the nudix hydrolase family
BFW41_18945	COG3066	DNA modification
BFW41_18955	COG0335	large ribosomal subunit rRNA binding
BFW41_18960	COG0336	Belongs to the RNA methyltransferase TrmD family
BFW41_18965	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
BFW41_18970	COG0228	four-way junction DNA binding
BFW41_18975	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
BFW41_18980	COG4137	Cytochrome C assembly protein
BFW41_18985	COG4536	flavin adenine dinucleotide binding
BFW41_18995	COG1017	nitric oxide dioxygenase activity
BFW41_18995	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
BFW41_19000	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
BFW41_19010	COG0039	L-malate dehydrogenase activity
BFW41_19015	COG4160	amino acid transport
BFW41_19020	COG4215	(ABC) transporter
BFW41_19025	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BFW41_19030	COG1126	abc transporter atp-binding protein
BFW41_19035	COG1438	arginine binding
BFW41_19040	COG2837	iron assimilation
BFW41_19045	COG3842	ATPase activity
BFW41_19055	COG1840	ABC-type Fe3 transport system, periplasmic component
BFW41_19060	COG0347	Belongs to the P(II) protein family
BFW41_19075	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BFW41_19080	COG0583	DNA-binding transcription factor activity
BFW41_19095	COG1929	Belongs to the glycerate kinase type-1 family
BFW41_19100	COG2610	gluconate transmembrane transporter activity
BFW41_19105	COG3835	regulator
BFW41_19110	COG3112	Uncharacterised protein family (UPF0231)
BFW41_19125	COG0840	transmembrane signaling receptor activity
BFW41_19130	COG3568	Endonuclease Exonuclease Phosphatase
BFW41_19145	COG0513	Belongs to the DEAD box helicase family
BFW41_19185	COG1448	Aminotransferase
BFW41_19200	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
BFW41_19205	COG1328	CTP reductase activity
BFW41_19225	COG4946	Tricorn protease homolog
BFW41_19225	COG0793	Belongs to the peptidase S41A family
BFW41_19265	COG0840	transmembrane signaling receptor activity
BFW41_19270	COG3397	chitin binding
BFW41_19275	COG0583	DNA-binding transcription factor activity
BFW41_19280	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
BFW41_19285	COG4208	sulfate ABC transporter
BFW41_19290	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
BFW41_19300	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
BFW41_19305	COG3174	membrane
BFW41_19310	COG0110	maltose O-acetyltransferase activity
BFW41_19335	COG0165	Argininosuccinate lyase
BFW41_19340	COG0137	argininosuccinate synthase activity
BFW41_19350	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
BFW41_19355	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
BFW41_19365	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
BFW41_19375	COG0527	aspartate kinase activity
BFW41_19375	COG0460	homoserine dehydrogenase
BFW41_19380	COG0626	cystathionine gamma-synthase activity
BFW41_19395	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BFW41_19400	COG0814	amino acid
BFW41_19405	COG1218	3'(2'),5'-bisphosphate nucleotidase
BFW41_19410	COG0494	nUDIX hydrolase
BFW41_19415	COG1011	Hydrolase
BFW41_19420	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
BFW41_19435	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
BFW41_19445	COG3156	type II secretion system protein K
BFW41_19450	COG4795	General secretion pathway protein
BFW41_19455	COG2165	general secretion pathway protein
BFW41_19465	COG2165	general secretion pathway protein
BFW41_19470	COG1459	type II secretion system
BFW41_19475	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
BFW41_19485	COG3031	protein transport across the cell outer membrane
BFW41_19495	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
BFW41_19520	COG0456	acetyltransferase
BFW41_19525	COG3133	Outer membrane lipoprotein
BFW41_19540	COG2771	luxR family
BFW41_19545	COG3916	Acyl-homoserine-lactone synthase
BFW41_19555	COG4776	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction
BFW41_19560	COG1309	transcriptional regulator
BFW41_19570	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
BFW41_19570	COG2213	PTS system mannitol-specific
BFW41_19575	COG0246	Mannitol dehydrogenase
BFW41_19580	COG3722	fumarate hydratase activity
BFW41_19585	COG3263	regulation of cellular component size
BFW41_19610	COG1671	Belongs to the UPF0178 family
BFW41_19625	COG1988	membrane-bound metal-dependent
BFW41_19630	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BFW41_19635	COG0513	Belongs to the DEAD box helicase family
BFW41_19660	COG1575	Belongs to the MenA family. Type 1 subfamily
BFW41_19665	COG1169	isochorismate synthase
BFW41_19670	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
BFW41_19675	COG0596	Alpha beta hydrolase
BFW41_19680	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
BFW41_19685	COG1441	menaquinone biosynthetic process
BFW41_19690	COG0318	PFAM AMP-dependent synthetase and ligase
BFW41_19705	COG3539	Fimbrial protein
BFW41_19710	COG3121	Chaperone
BFW41_19715	COG3188	usher protein
BFW41_19725	COG3539	Fimbrial protein
BFW41_19735	COG3291	Pkd domain containing protein
BFW41_19740	COG2949	membrane
BFW41_19755	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
BFW41_19760	COG5380	lipid catabolic process
BFW41_19780	COG2873	o-acetylhomoserine
BFW41_19790	COG1979	alcohol dehydrogenase
BFW41_19810	COG4221	oxidoreductase activity
BFW41_19830	COG1285	pathogenesis
BFW41_19850	COG1368	sulfuric ester hydrolase activity
BFW41_19855	COG1522	sequence-specific DNA binding
BFW41_19865	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
BFW41_19870	COG1418	mRNA catabolic process
BFW41_19875	COG1546	Belongs to the CinA family
BFW41_19875	COG1058	Belongs to the CinA family
BFW41_19885	COG0842	Transport permease protein
BFW41_19885	COG1129	ABC transporter
BFW41_19900	COG0561	phosphatase activity
BFW41_19905	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
BFW41_19925	COG1011	Hydrolase
BFW41_19940	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
BFW41_19945	COG0019	diaminopimelate decarboxylase activity
BFW41_19950	COG1965	Belongs to the frataxin family
BFW41_19955	COG0400	carboxylic ester hydrolase activity
BFW41_19960	COG3072	Adenylate cyclase
BFW41_19965	COG0181	hydroxymethylbilane synthase activity
BFW41_19975	COG2959	enzyme of heme biosynthesis
BFW41_19990	COG1494	fructose-1,6-bisphosphatase
BFW41_20030	COG1733	regulation of RNA biosynthetic process
BFW41_20050	COG3932	Exopolysaccharide synthesis, ExoD
BFW41_20055	COG0814	amino acid
BFW41_20060	COG3706	GGDEF domain
BFW41_20075	COG3417	Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1B (PBP1b)
BFW41_20085	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
BFW41_20090	COG2022	thiamine diphosphate biosynthetic process
BFW41_20100	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
BFW41_20105	COG0352	thiamine-phosphate diphosphorylase activity
BFW41_20110	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
BFW41_20130	COG0745	RESPONSE REGULATOR receiver
BFW41_20140	COG1114	Component of the transport system for branched-chain amino acids
BFW41_20145	COG0189	ligase activity
BFW41_20165	COG1639	'signal transduction protein
BFW41_20175	COG2321	neutral zinc metallopeptidase
BFW41_20180	COG3700	Belongs to the class B bacterial acid phosphatase family
BFW41_20205	COG2172	sigma factor antagonist activity
BFW41_20210	COG0784	Response regulator, receiver
BFW41_20210	COG5002	protein histidine kinase activity
BFW41_20210	COG2205	protein histidine kinase activity
BFW41_20215	COG3437	response regulator, receiver
BFW41_20225	COG0477	Major facilitator Superfamily
BFW41_20240	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
BFW41_20245	COG1263	PTS System
BFW41_20245	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BFW41_20265	COG0312	modulator of DNA gyrase
BFW41_20270	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BFW41_20280	COG3164	Protein of unknown function
BFW41_20285	COG1530	ribonuclease E activity
BFW41_20290	COG0424	maF-like protein
BFW41_20295	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
BFW41_20300	COG1792	Involved in formation and maintenance of cell shape
BFW41_20305	COG1077	Cell shape determining protein MreB Mrl
BFW41_20330	COG4968	Prepilin-type N-terminal cleavage methylation domain
BFW41_20335	COG4969	Belongs to the N-Me-Phe pilin family
BFW41_20350	COG1459	type II secretion system
BFW41_20355	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
BFW41_20400	COG2200	EAL domain
BFW41_20400	COG2199	diguanylate cyclase activity
BFW41_20405	COG2200	EAL domain
BFW41_20410	COG0387	Pfam Sodium calcium exchanger
BFW41_20415	COG2986	histidine ammonia-lyase
BFW41_20420	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
BFW41_20425	COG0010	Belongs to the arginase family
BFW41_20430	COG1228	amidohydrolase
BFW41_20435	COG2188	Transcriptional regulator
BFW41_20440	COG0288	reversible hydration of carbon dioxide
BFW41_20450	COG2177	Part of the ABC transporter FtsEX involved in
BFW41_20455	COG2884	Cell division ATP-binding protein ftsE
BFW41_20465	COG0742	ribosomal rna small subunit methyltransferase
BFW41_20490	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BFW41_20495	COG0741	lytic transglycosylase activity
BFW41_20515	COG2095	MarC family integral membrane protein
BFW41_20525	COG1301	dicarboxylic acid transport
BFW41_20550	COG3714	YhhN family
BFW41_20565	COG1770	oligopeptidase
BFW41_20580	COG4221	oxidoreductase activity
BFW41_20585	COG0583	DNA-binding transcription factor activity
BFW41_20590	COG2249	NAD(P)H dehydrogenase (quinone) activity
BFW41_20645	COG0202	RNA polymerase activity
BFW41_20650	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
BFW41_20655	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
BFW41_20660	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
BFW41_20665	COG0201	protein transport
BFW41_20670	COG0200	Binds to the 23S rRNA
BFW41_20675	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
BFW41_20680	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
BFW41_20685	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
BFW41_20690	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
BFW41_20695	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
BFW41_20700	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
BFW41_20705	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
BFW41_20710	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
BFW41_20715	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
BFW41_20720	COG0255	Belongs to the universal ribosomal protein uL29 family
BFW41_20725	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
BFW41_20730	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
BFW41_20735	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
BFW41_20740	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
BFW41_20745	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
BFW41_20750	COG0089	rRNA binding
BFW41_20755	COG0088	Forms part of the polypeptide exit tunnel
BFW41_20760	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
BFW41_20765	COG0051	transcription antitermination factor activity, RNA binding
BFW41_20780	COG0745	RESPONSE REGULATOR receiver
BFW41_20785	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
BFW41_20790	COG2183	response to ionizing radiation
BFW41_20810	COG0596	Alpha beta hydrolase
BFW41_20815	COG1040	competence protein
BFW41_20820	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
BFW41_20820	COG0316	Belongs to the HesB IscA family
BFW41_20825	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
BFW41_20830	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
BFW41_20835	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BFW41_20840	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
BFW41_20845	COG4942	peptidase
BFW41_20855	COG1609	Transcriptional regulator
BFW41_20860	COG0800	Aldolase
BFW41_20865	COG0129	dihydroxy-acid dehydratase activity
BFW41_20870	COG3265	gluconokinase activity
BFW41_20875	COG2610	gluconate transmembrane transporter activity
BFW41_20880	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BFW41_20885	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
BFW41_20895	COG0456	acetyltransferase
BFW41_20905	COG1490	D-aminoacyl-tRNA deacylase activity
BFW41_20910	COG1295	ribonuclease BN
BFW41_20915	COG1295	ribonuclease BN
BFW41_20925	COG0174	glutamine synthetase
BFW41_20935	COG3852	Histidine kinase
BFW41_20940	COG2204	response regulator
BFW41_20945	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
BFW41_20950	COG0635	Involved in the biosynthesis of porphyrin-containing compound
BFW41_20960	COG3078	GTPase activator activity
BFW41_20970	COG0218	Necessary for normal cell division and for the maintenance of normal septation
BFW41_20980	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
BFW41_20985	COG0408	coproporphyrinogen oxidase activity
BFW41_20990	COG0009	L-threonylcarbamoyladenylate synthase
BFW41_21000	COG0551	DNA topoisomerase type I activity
BFW41_21005	COG2922	Belongs to the Smg family
BFW41_21010	COG0758	DNA mediated transformation
BFW41_21020	COG0242	peptide deformylase activity
BFW41_21025	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
BFW41_21030	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
BFW41_21030	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
BFW41_21035	COG0569	domain protein
BFW41_21040	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
BFW41_21045	COG1322	Protein conserved in bacteria
BFW41_21065	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BFW41_21070	COG0686	Belongs to the AlaDH PNT family
BFW41_21075	COG0519	Catalyzes the synthesis of GMP from XMP
BFW41_21075	COG0518	GMP synthase (glutamine-hydrolyzing) activity
BFW41_21090	COG1396	sequence-specific DNA binding
BFW41_21095	COG1012	belongs to the aldehyde dehydrogenase family
BFW41_21105	COG2962	Rard protein
BFW41_21115	COG1280	lysine exporter protein (LysE YggA)
BFW41_21125	COG0840	transmembrane signaling receptor activity
BFW41_21130	COG2391	methyltransferase activity
BFW41_21140	COG1280	lysine exporter protein (LysE YggA)
BFW41_21195	COG0583	DNA-binding transcription factor activity
BFW41_21200	COG1943	Transposase
BFW41_21205	COG0210	DNA helicase
BFW41_21230	COG0583	DNA-binding transcription factor activity
BFW41_21250	COG1262	PFAM Formylglycine-generating sulfatase enzyme
BFW41_21255	COG0385	Bile acid
BFW41_21260	COG0531	amino acid
BFW41_21265	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BFW41_21270	COG0531	amino acid
BFW41_21275	COG2731	YhcH YjgK YiaL family protein
BFW41_21280	COG3250	beta-galactosidase activity
BFW41_21285	COG1609	Transcriptional regulator
BFW41_21320	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
BFW41_21325	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BFW41_21325	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BFW41_21330	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
BFW41_21335	COG3074	FtsZ-dependent cytokinesis
BFW41_21345	COG1045	serine acetyltransferase
BFW41_21355	COG0745	RESPONSE REGULATOR receiver
BFW41_21360	COG2205	protein histidine kinase activity
BFW41_21365	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
BFW41_21370	COG0534	Mate efflux family protein
BFW41_21385	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
BFW41_21390	COG2937	Belongs to the GPAT DAPAT family
BFW41_21395	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
BFW41_21400	COG3161	chorismate lyase activity
BFW41_21405	COG1580	Controls the rotational direction of flagella during chemotaxis
BFW41_21415	COG0604	alcohol dehydrogenase
BFW41_21420	COG1609	Transcriptional regulator
BFW41_21440	COG1519	Transferase
BFW41_21445	COG0859	PFAM glycosyl transferase family 9
BFW41_21450	COG0463	Glycosyl transferase, family 2
BFW41_21455	COG0859	PFAM glycosyl transferase family 9
BFW41_21460	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
BFW41_21465	COG2990	Protein conserved in bacteria
BFW41_21470	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
BFW41_21480	COG0267	Belongs to the bacterial ribosomal protein bL33 family
BFW41_21485	COG2003	Belongs to the UPF0758 family
BFW41_21490	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
BFW41_21495	COG0756	dUTP diphosphatase activity
BFW41_21500	COG1309	transcriptional regulator
BFW41_21505	COG0668	transmembrane transport
BFW41_21515	COG0166	Belongs to the GPI family
BFW41_21520	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
BFW41_21525	COG0583	DNA-binding transcription factor activity
BFW41_21565	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
BFW41_21570	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
BFW41_21575	COG1739	Uncharacterized protein family UPF0029
BFW41_21580	COG0006	proline dipeptidase activity
BFW41_21585	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BFW41_21590	COG1024	Enoyl-CoA hydratase
BFW41_21590	COG1250	3-hydroxyacyl-CoA dehydrogenase
BFW41_21595	COG0183	Belongs to the thiolase family
BFW41_21600	COG0745	RESPONSE REGULATOR receiver
BFW41_21605	COG2205	protein histidine kinase activity
BFW41_21620	COG0425	Belongs to the sulfur carrier protein TusA family
BFW41_21625	COG0251	oxidation-reduction process
BFW41_21630	COG2885	chlorophyll binding
BFW41_21635	COG1335	isochorismatase
BFW41_21640	COG2818	Glycosylase
BFW41_21645	COG0752	glycyl-tRNA synthetase alpha subunit
BFW41_21650	COG0751	glycine-tRNA ligase activity
BFW41_21655	COG0529	Catalyzes the synthesis of activated sulfate
BFW41_21690	COG0814	amino acid
BFW41_21695	COG0348	domain, Protein
BFW41_21705	COG0446	pyridine nucleotide-disulphide oxidoreductase
BFW41_21710	COG0426	domain, Protein
BFW41_21710	COG1773	rubredoxin
BFW41_21715	COG3604	Transcriptional regulator
BFW41_21720	COG2188	Transcriptional regulator
BFW41_21735	COG1609	Transcriptional regulator
BFW41_21745	COG0559	Belongs to the binding-protein-dependent transport system permease family
BFW41_21775	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BFW41_21800	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
BFW41_21810	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
BFW41_21815	COG3118	belongs to the thioredoxin family
BFW41_21820	COG0513	Belongs to the DEAD box helicase family
BFW41_21825	COG0248	Ppx GppA phosphatase
BFW41_21840	COG0742	ribosomal rna small subunit methyltransferase
BFW41_21860	COG0084	hydrolase, TatD family'
BFW41_21865	COG0805	protein transport
BFW41_21870	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
BFW41_21880	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
BFW41_21885	COG3165	ubiquinone biosynthetic process from chorismate
BFW41_21895	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
BFW41_21900	COG0402	S-adenosylhomocysteine deaminase activity
BFW41_21945	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
BFW41_21950	COG0848	biopolymer transport protein
BFW41_21955	COG0811	peptide transport
BFW41_21960	COG0811	peptide transport
BFW41_21970	COG2771	luxR family
BFW41_21975	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
BFW41_21980	COG1349	DNA-binding transcription factor activity
BFW41_21985	COG0745	RESPONSE REGULATOR receiver
BFW41_21990	COG2205	protein histidine kinase activity
BFW41_22000	COG4452	Inner membrane protein CreD
BFW41_22005	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
BFW41_22010	COG0355	proton-transporting ATP synthase activity, rotational mechanism
BFW41_22015	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
BFW41_22020	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
BFW41_22025	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
BFW41_22030	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
BFW41_22035	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
BFW41_22045	COG0356	it plays a direct role in the translocation of protons across the membrane
BFW41_22055	COG1475	DNA binding
BFW41_22060	COG1192	Involved in chromosome partitioning
BFW41_22065	COG0357	Ribosomal RNA small subunit methyltransferase G
BFW41_22070	COG0445	tRNA wobble uridine modification
BFW41_22075	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
BFW41_22080	COG4774	siderophore transport
BFW41_22085	COG4615	Cyclic peptide transporter
BFW41_22090	COG1120	ATPase activity
BFW41_22105	COG3550	peptidyl-serine autophosphorylation
BFW41_22165	COG5001	Diguanylate cyclase
BFW41_22165	COG3300	MHYT domain
BFW41_22175	COG3316	Transposase and inactivated derivatives
BFW41_22185	COG3316	Transposase and inactivated derivatives
BFW41_22190	COG3173	Aminoglycoside phosphotransferase
BFW41_22210	COG3316	Transposase and inactivated derivatives
BFW41_22250	COG1357	PFAM Pentapeptide repeats (8 copies)
BFW41_22285	COG0732	type I restriction modification DNA specificity domain
BFW41_22325	COG4974	Belongs to the 'phage' integrase family
BFW41_22330	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
BFW41_22335	COG0706	membrane insertase activity
BFW41_22340	COG0594	ribonuclease P activity
BFW41_22345	COG0230	Belongs to the bacterial ribosomal protein bL34 family