locus-tag	class	description
FT669_00020	COG5002	protein histidine kinase activity
FT669_00025	COG0745	RESPONSE REGULATOR receiver
FT669_00030	COG0346	lactoylglutathione lyase activity
FT669_00035	COG3706	GGDEF domain
FT669_00055	COG3290	protein histidine kinase activity
FT669_00105	COG0602	queuosine metabolic process
FT669_00110	COG1328	CTP reductase activity
FT669_00120	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
FT669_00125	COG3115	cell septum assembly
FT669_00140	COG2860	membrane
FT669_00150	COG3108	Peptidase M15
FT669_00155	COG2989	Protein conserved in bacteria
FT669_00165	COG0463	Glycosyl transferase, family 2
FT669_00225	COG3590	peptidase
FT669_00240	COG1982	Orn Lys Arg decarboxylase major
FT669_00245	COG0531	amino acid
FT669_00250	COG3710	Transcriptional regulator
FT669_00255	COG0531	amino acid
FT669_00275	COG0814	amino acid
FT669_00305	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
FT669_00310	COG0739	heme binding
FT669_00315	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
FT669_00335	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
FT669_00355	COG1385	rRNA (uridine-N3-)-methyltransferase activity
FT669_00375	COG1678	Uncharacterized ACR, COG1678
FT669_00380	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
FT669_00385	COG3104	oligopeptide transport
FT669_00435	COG1115	amino acid carrier protein
FT669_00440	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
FT669_00450	COG0825	malonyl-CoA metabolic process
FT669_00460	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
FT669_00465	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FT669_00470	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FT669_00475	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
FT669_00480	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FT669_00490	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FT669_00495	COG0750	zinc metalloprotease
FT669_00500	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
FT669_00505	COG0575	Belongs to the CDS family
FT669_00510	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
FT669_00515	COG0233	cytoplasmic translational termination
FT669_00520	COG0528	UMP kinase activity
FT669_00525	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
FT669_00530	COG0052	Belongs to the universal ribosomal protein uS2 family
FT669_00535	COG0024	Methionine aminopeptidase
FT669_00545	COG2171	N-acyltransferase activity
FT669_00565	COG4580	involved in the transport of maltose and maltodextrins
FT669_00575	COG0564	pseudouridine synthase activity
FT669_00580	COG3098	single-species biofilm formation
FT669_00605	COG5595	Zn-ribbon-containing, possibly nucleic-acid-binding protein (DUF2310)
FT669_00615	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
FT669_00615	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
FT669_00630	COG1611	Belongs to the LOG family
FT669_00635	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FT669_00640	COG0473	3-isopropylmalate dehydrogenase activity
FT669_00650	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
FT669_00655	COG2363	Small membrane protein
FT669_00665	COG0583	DNA-binding transcription factor activity
FT669_00670	COG0840	transmembrane signaling receptor activity
FT669_00690	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
FT669_00695	COG1666	GTP binding
FT669_00700	COG3248	Nucleoside-binding outer membrane protein
FT669_00710	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
FT669_00720	COG2813	Specifically methylates the guanine in position
FT669_00725	COG0271	Belongs to the BolA IbaG family
FT669_00730	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
FT669_00735	COG1805	sodium ion transport
FT669_00740	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
FT669_00745	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
FT669_00750	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
FT669_00755	COG2871	sodium ion transport
FT669_00760	COG1477	protein flavinylation
FT669_00805	COG0300	oxidoreductase activity
FT669_00815	COG0415	Belongs to the DNA photolyase family
FT669_00820	COG0789	Transcriptional regulator
FT669_00825	COG3272	Protein of unknown function (DUF1722)
FT669_00855	COG0077	Prephenate dehydratase
FT669_00855	COG1605	Chorismate mutase
FT669_00960	COG2916	Histone family protein nucleoid-structuring protein H-NS
FT669_00995	COG1160	GTP binding
FT669_01055	COG0300	oxidoreductase activity
FT669_01080	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
FT669_01100	COG0826	peptidase U32
FT669_01105	COG1280	lysine exporter protein (LysE YggA)
FT669_01125	COG0745	RESPONSE REGULATOR receiver
FT669_01150	COG0840	transmembrane signaling receptor activity
FT669_01160	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
FT669_01170	COG1185	polyribonucleotide nucleotidyltransferase activity
FT669_01175	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
FT669_01180	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
FT669_01185	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
FT669_01190	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
FT669_01195	COG0195	Participates in both transcription termination and antitermination
FT669_01200	COG0779	Required for maturation of 30S ribosomal subunits
FT669_01215	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
FT669_01220	COG0149	triose-phosphate isomerase activity
FT669_01225	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FT669_01230	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
FT669_01245	COG1534	Rna-binding protein
FT669_01265	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
FT669_01270	COG1722	exodeoxyribonuclease VII activity
FT669_01275	COG0142	geranyltranstransferase activity
FT669_01280	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
FT669_01290	COG0601	transmembrane transport
FT669_01295	COG4166	transmembrane transport
FT669_01305	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
FT669_01315	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
FT669_01345	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
FT669_01355	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
FT669_01370	COG1879	ABC-type sugar transport system periplasmic component
FT669_01380	COG0745	RESPONSE REGULATOR receiver
FT669_01385	COG3005	denitrification pathway
FT669_01395	COG3381	protein complex oligomerization
FT669_01415	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FT669_01420	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
FT669_01425	COG0511	ligase activity, forming carbon-carbon bonds
FT669_01430	COG0439	Biotin carboxylase
FT669_01435	COG3924	membrane
FT669_01440	COG4145	pantothenate transmembrane transporter activity
FT669_01445	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FT669_01445	COG1263	PTS System
FT669_01445	COG2190	(PTS) system
FT669_01450	COG0583	DNA-binding transcription factor activity
FT669_01460	COG2264	protein methyltransferase activity
FT669_01470	COG0778	Nitroreductase
FT669_01490	COG4174	ABC transporter (Permease)
FT669_01505	COG4608	Belongs to the ABC transporter superfamily
FT669_01525	COG3416	Protein conserved in bacteria
FT669_01535	COG0741	lytic transglycosylase activity
FT669_01540	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
FT669_01555	COG0488	(ABC) transporter
FT669_01570	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FT669_01575	COG0840	transmembrane signaling receptor activity
FT669_01585	COG1278	Cold shock
FT669_01625	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
FT669_01630	COG1162	GTPase activity
FT669_01635	COG0688	phosphatidylethanolamine metabolic process
FT669_01640	COG4628	conserved protein (DUF2132)
FT669_01655	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
FT669_01670	COG1073	alpha beta
FT669_01675	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
FT669_01795	COG4695	Portal protein
FT669_01965	COG3178	'Phosphotransferase
FT669_01975	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FT669_01990	COG2967	ApaG domain
FT669_01995	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
FT669_02005	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FT669_02015	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
FT669_02020	COG0211	Belongs to the bacterial ribosomal protein bL27 family
FT669_02025	COG0261	This protein binds to 23S rRNA in the presence of protein L20
FT669_02030	COG0142	geranyltranstransferase activity
FT669_02035	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
FT669_02040	COG0330	HflC and HflK could
FT669_02045	COG0330	HflC and HflK could
FT669_02050	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
FT669_02055	COG1923	regulation of RNA biosynthetic process
FT669_02065	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
FT669_02075	COG0802	atpase or kinase
FT669_02100	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
FT669_02105	COG2011	ABC-type metal ion transport system permease component
FT669_02110	COG1464	Belongs to the NlpA lipoprotein family
FT669_02145	COG0784	Response regulator, receiver
FT669_02145	COG2198	Histidine kinase
FT669_02145	COG5002	protein histidine kinase activity
FT669_02155	COG3385	transposase activity
FT669_02185	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
FT669_02190	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
FT669_02195	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FT669_02200	COG2716	regulation of RNA biosynthetic process
FT669_02205	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
FT669_02210	COG3013	Belongs to the UPF0304 family
FT669_02220	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
FT669_02230	COG1555	photosystem II stabilization
FT669_02235	COG1210	Utp--glucose-1-phosphate uridylyltransferase
FT669_02240	COG3104	oligopeptide transport
FT669_02245	COG0745	RESPONSE REGULATOR receiver
FT669_02275	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FT669_02325	COG0440	acetolactate synthase activity
FT669_02330	COG0028	Belongs to the TPP enzyme family
FT669_02345	COG0671	phosphoesterase, PA-phosphatase related
FT669_02360	COG0473	3-isopropylmalate dehydrogenase activity
FT669_02365	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
FT669_02370	COG0066	3-isopropylmalate dehydratase activity
FT669_02390	COG1178	ABC-type Fe3 transport system permease component
FT669_02395	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
FT669_02460	COG0459	protein refolding
FT669_02465	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
FT669_02475	COG3030	protein affecting phage T7 exclusion by the F plasmid
FT669_02480	COG1027	Aspartate ammonia-lyase
FT669_02485	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
FT669_02495	COG0828	Belongs to the bacterial ribosomal protein bS21 family
FT669_02500	COG1610	YqeY-like protein
FT669_02505	COG0358	DNA primase activity
FT669_02510	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
FT669_02530	COG0151	Belongs to the GarS family
FT669_02535	COG0138	bifunctional purine biosynthesis protein purh
FT669_02545	COG3036	rescue of stalled ribosome
FT669_02550	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FT669_02555	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
FT669_02575	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FT669_02580	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FT669_02590	COG0583	DNA-binding transcription factor activity
FT669_02595	COG0477	Major facilitator Superfamily
FT669_02605	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
FT669_02635	COG0456	acetyltransferase
FT669_02640	COG1022	Amp-dependent synthetase and ligase
FT669_02645	COG2918	glutathione biosynthetic process
FT669_02670	COG3385	transposase activity
FT669_02685	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
FT669_02690	COG0359	binds to the 23S rRNA
FT669_02695	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
FT669_02700	COG0360	Binds together with S18 to 16S ribosomal RNA
FT669_02705	COG1914	H( )-stimulated, divalent metal cation uptake system
FT669_02710	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
FT669_02720	COG0776	regulation of translation
FT669_02725	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
FT669_02765	COG0813	purine-nucleoside phosphorylase activity
FT669_02770	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
FT669_02775	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
FT669_02780	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
FT669_02790	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
FT669_02795	COG0084	hydrolase, TatD family'
FT669_02800	COG2165	general secretion pathway protein
FT669_02810	COG1854	S-ribosylhomocysteine lyase activity
FT669_02825	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FT669_02825	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
FT669_02830	COG4969	Belongs to the N-Me-Phe pilin family
FT669_02870	COG1047	Peptidyl-prolyl cis-trans
FT669_02875	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
FT669_02885	COG0196	riboflavin kinase activity
FT669_02890	COG0728	peptidoglycan biosynthetic process
FT669_02895	COG0268	Binds directly to 16S ribosomal RNA
FT669_02900	COG0640	Transcriptional regulator
FT669_02905	COG0583	DNA-binding transcription factor activity
FT669_02915	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
FT669_02920	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
FT669_02925	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
FT669_02930	COG3605	phosphoenolpyruvate-protein phosphotransferase activity
FT669_02935	COG1051	belongs to the nudix hydrolase family
FT669_02950	COG0335	large ribosomal subunit rRNA binding
FT669_02955	COG0336	Belongs to the RNA methyltransferase TrmD family
FT669_02960	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
FT669_02965	COG0228	four-way junction DNA binding
FT669_02970	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
FT669_02980	COG4536	flavin adenine dinucleotide binding
FT669_02995	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
FT669_03000	COG0039	L-malate dehydrogenase activity
FT669_03005	COG4160	amino acid transport
FT669_03010	COG4215	(ABC) transporter
FT669_03015	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FT669_03025	COG1438	arginine binding
FT669_03030	COG2837	iron assimilation
FT669_03045	COG1840	ABC-type Fe3 transport system, periplasmic component
FT669_03070	COG3022	response to hydroperoxide
FT669_03085	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
FT669_03090	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
FT669_03100	COG1872	DUF167
FT669_03110	COG3385	transposase activity
FT669_03115	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
FT669_03120	COG0583	DNA-binding transcription factor activity
FT669_03140	COG2610	gluconate transmembrane transporter activity
FT669_03145	COG3835	regulator
FT669_03150	COG3112	Uncharacterised protein family (UPF0231)
FT669_03180	COG0513	Belongs to the DEAD box helicase family
FT669_03220	COG1448	Aminotransferase
FT669_03235	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
FT669_03240	COG1328	CTP reductase activity
FT669_03255	COG0633	Ferredoxin
FT669_03255	COG0543	2 iron, 2 sulfur cluster binding
FT669_03270	COG0840	transmembrane signaling receptor activity
FT669_03275	COG3397	chitin binding
FT669_03280	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FT669_03295	COG0765	amino acid transport
FT669_03300	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
FT669_03305	COG0583	DNA-binding transcription factor activity
FT669_03310	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
FT669_03315	COG4208	sulfate ABC transporter
FT669_03320	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
FT669_03330	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
FT669_03340	COG0110	maltose O-acetyltransferase activity
FT669_03355	COG1011	Hydrolase
FT669_03360	COG0494	nUDIX hydrolase
FT669_03365	COG1218	3'(2'),5'-bisphosphate nucleotidase
FT669_03370	COG0814	amino acid
FT669_03375	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FT669_03395	COG0527	aspartate kinase activity
FT669_03395	COG0460	homoserine dehydrogenase
FT669_03400	COG0306	phosphate transporter
FT669_03405	COG1392	Phosphate transport regulator
FT669_03410	COG3025	triphosphatase activity
FT669_03415	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FT669_03425	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
FT669_03465	COG1757	Na H antiporter
FT669_03470	COG0316	Belongs to the HesB IscA family
FT669_03485	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
FT669_03540	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
FT669_03545	COG0564	pseudouridine synthase activity
FT669_03565	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FT669_03565	COG1263	PTS System
FT669_03595	COG0586	Pfam SNARE associated Golgi protein
FT669_03600	COG1686	Belongs to the peptidase S11 family
FT669_03635	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
FT669_03640	COG0527	aspartate kinase activity
FT669_03645	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
FT669_03655	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
FT669_03660	COG1546	Belongs to the CinA family
FT669_03665	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
FT669_03685	COG1380	Effector of murein hydrolase LrgA
FT669_03735	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
FT669_03745	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
FT669_03750	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
FT669_03760	COG0137	argininosuccinate synthase activity
FT669_03805	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
FT669_03810	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
FT669_03825	COG0477	Major facilitator Superfamily
FT669_03830	COG0523	cobalamin synthesis protein
FT669_03840	COG2200	EAL domain
FT669_03845	COG1049	propionate catabolic process, 2-methylcitrate cycle
FT669_03865	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FT669_03870	COG0508	dehydrogenase complex catalyzes the overall conversion of
FT669_03875	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
FT669_03880	COG2186	Transcriptional regulator
FT669_03910	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
FT669_03915	COG1459	type II secretion system
FT669_03930	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
FT669_03935	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
FT669_03940	COG0494	nUDIX hydrolase
FT669_03945	COG0653	protein targeting
FT669_03955	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
FT669_03960	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
FT669_03965	COG0849	cell division
FT669_03975	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
FT669_03980	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
FT669_03990	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
FT669_04000	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
FT669_04005	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
FT669_04010	COG0768	penicillin binding
FT669_04015	COG3116	cell division
FT669_04020	COG0275	rRNA processing
FT669_04025	COG2001	Belongs to the MraZ family
FT669_04035	COG0741	lytic transglycosylase activity
FT669_04035	COG1388	LysM domain
FT669_04045	COG1360	Flagellar Motor Protein
FT669_04050	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
FT669_04055	COG1191	sigma factor activity
FT669_04080	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
FT669_04085	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
FT669_04100	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
FT669_04115	COG1706	bacterial-type flagellum-dependent cell motility
FT669_04125	COG4786	Flagellar basal body rod
FT669_04150	COG1815	bacterial-type flagellum-dependent cell motility
FT669_04160	COG2747	anti-sigma28 factor FlgM
FT669_04185	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
FT669_04195	COG1677	Flagellar hook-basal body complex protein FliE
FT669_04245	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
FT669_04250	COG3107	peptidoglycan biosynthetic process
FT669_04255	COG0792	nuclease activity
FT669_04260	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
FT669_04270	COG2969	positive regulation of protein catabolic process
FT669_04275	COG0625	glutathione transferase activity
FT669_04280	COG2857	Cytochrome c1
FT669_04290	COG0723	plastoquinol--plastocyanin reductase activity
FT669_04295	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
FT669_04300	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
FT669_04305	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
FT669_04315	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FT669_04320	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FT669_04355	COG3964	amidohydrolase
FT669_04375	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
FT669_04380	COG1660	Displays ATPase and GTPase activities
FT669_04385	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FT669_04400	COG1137	ATPase activity
FT669_04405	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
FT669_04415	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
FT669_04420	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
FT669_04420	COG0517	IMP dehydrogenase activity
FT669_04425	COG1127	ABC transporter
FT669_04430	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
FT669_04435	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
FT669_04440	COG2854	intermembrane phospholipid transfer
FT669_04450	COG5007	Belongs to the BolA IbaG family
FT669_04460	COG0312	modulator of DNA gyrase
FT669_04465	COG3028	Belongs to the UPF0307 family
FT669_04480	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FT669_04505	COG0019	diaminopimelate decarboxylase activity
FT669_04515	COG1965	Belongs to the frataxin family
FT669_04525	COG3072	Adenylate cyclase
FT669_04530	COG0181	hydroxymethylbilane synthase activity
FT669_04540	COG2959	enzyme of heme biosynthesis
FT669_04555	COG1494	fructose-1,6-bisphosphatase
FT669_04580	COG1686	Belongs to the peptidase S11 family
FT669_04585	COG3385	transposase activity
FT669_04620	COG0795	lipopolysaccharide-transporting ATPase activity
FT669_04625	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
FT669_04630	COG2927	DNA polymerase III (CHI subunit)
FT669_04655	COG0454	-acetyltransferase
FT669_04655	COG0456	acetyltransferase
FT669_04660	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
FT669_04660	COG0456	acetyltransferase
FT669_04685	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
FT669_04695	COG5380	lipid catabolic process
FT669_04720	COG2873	o-acetylhomoserine
FT669_04750	COG3842	ATPase activity
FT669_04760	COG1175	transmembrane transport
FT669_04785	COG3069	C4-dicarboxylate transmembrane transporter activity
FT669_04805	COG2199	diguanylate cyclase activity
FT669_04805	COG2203	Gaf domain
FT669_04815	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
FT669_04820	COG1074	ATP-dependent DNA helicase activity
FT669_04830	COG2259	Doxx family
FT669_04835	COG1741	Belongs to the pirin family
FT669_04845	COG0583	DNA-binding transcription factor activity
FT669_04865	COG3706	GGDEF domain
FT669_04905	COG0203	ribosomal protein L17
FT669_04910	COG0202	RNA polymerase activity
FT669_04915	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
FT669_04920	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
FT669_04925	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
FT669_04930	COG0257	Belongs to the bacterial ribosomal protein bL36 family
FT669_04935	COG0201	protein transport
FT669_04940	COG0200	Binds to the 23S rRNA
FT669_04945	COG1841	ribosomal large subunit assembly
FT669_04950	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
FT669_04955	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
FT669_04960	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
FT669_04965	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
FT669_04970	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
FT669_04975	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
FT669_04980	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
FT669_04985	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
FT669_04990	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
FT669_04995	COG0255	Belongs to the universal ribosomal protein uL29 family
FT669_05000	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
FT669_05005	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
FT669_05010	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
FT669_05015	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
FT669_05020	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
FT669_05025	COG0089	rRNA binding
FT669_05030	COG0088	Forms part of the polypeptide exit tunnel
FT669_05035	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
FT669_05040	COG0051	transcription antitermination factor activity, RNA binding
FT669_05060	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
FT669_05065	COG2183	response to ionizing radiation
FT669_05085	COG0596	Alpha beta hydrolase
FT669_05095	COG0316	Belongs to the HesB IscA family
FT669_05095	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
FT669_05105	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
FT669_05110	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FT669_05115	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
FT669_05120	COG4942	peptidase
FT669_05130	COG1609	Transcriptional regulator
FT669_05145	COG0800	Aldolase
FT669_05155	COG3265	gluconokinase activity
FT669_05160	COG2610	gluconate transmembrane transporter activity
FT669_05165	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FT669_05185	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
FT669_05195	COG1295	ribonuclease BN
FT669_05205	COG0814	amino acid
FT669_05225	COG0254	rRNA binding
FT669_05240	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
FT669_05245	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
FT669_05265	COG0514	ATP-dependent DNA helicase (RecQ)
FT669_05270	COG2050	protein possibly involved in aromatic compounds catabolism
FT669_05285	COG2258	MOSC domain
FT669_05290	COG1177	transmembrane transport
FT669_05295	COG1176	ABC-type spermidine putrescine transport system, permease component I
FT669_05300	COG3842	ATPase activity
FT669_05320	COG0174	glutamine synthetase
FT669_05340	COG3045	CreA protein
FT669_05345	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FT669_05380	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
FT669_05385	COG3385	transposase activity
FT669_05415	COG1609	Transcriptional regulator
FT669_05420	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
FT669_05425	COG1085	galactose-1-phosphate uridylyltransferase
FT669_05430	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
FT669_05435	COG2017	converts alpha-aldose to the beta-anomer
FT669_05440	COG1968	undecaprenyl-diphosphatase activity
FT669_05450	COG1595	DNA-templated transcription, initiation
FT669_05460	COG0018	arginyl-trna synthetase
FT669_05470	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
FT669_05475	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
FT669_05490	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FT669_05495	COG1131	(ABC) transporter
FT669_05500	COG0842	Transport permease protein
FT669_05505	COG0842	Transport permease protein
FT669_05510	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FT669_05520	COG2116	formate transmembrane transporter activity
FT669_05525	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
FT669_05525	COG1648	precorrin-2 dehydrogenase activity
FT669_05530	COG2239	Acts as a magnesium transporter
FT669_05540	COG0737	Belongs to the 5'-nucleotidase family
FT669_05545	COG1079	Belongs to the binding-protein-dependent transport system permease family
FT669_05550	COG4603	Belongs to the binding-protein-dependent transport system permease family
FT669_05555	COG3845	ABC transporter
FT669_05560	COG1744	ABC transporter substrate-binding protein PnrA-like
FT669_05565	COG0210	DNA helicase
FT669_05635	COG3706	GGDEF domain
FT669_05675	COG1280	lysine exporter protein (LysE YggA)
FT669_05700	COG3306	glycosyltransferase involved in LPS biosynthesis
FT669_05720	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FT669_05730	COG0156	8-amino-7-oxononanoate synthase activity
FT669_05740	COG3245	cytochrome
FT669_05755	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
FT669_05760	COG2166	iron-sulfur cluster assembly
FT669_05765	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
FT669_05805	COG0583	DNA-binding transcription factor activity
FT669_05820	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
FT669_05830	COG2223	nitrite transmembrane transporter activity
FT669_05835	COG3279	Response regulator of the LytR AlgR family
FT669_05840	COG3275	phosphorelay sensor kinase activity
FT669_05845	COG2081	HI0933 family
FT669_05850	COG1528	Iron-storage protein
FT669_05855	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
FT669_05860	COG0589	response to stress
FT669_05900	COG3642	lipopolysaccharide core region biosynthetic process
FT669_05905	COG0859	PFAM glycosyl transferase family 9
FT669_05920	COG1758	RNA polymerase activity
FT669_05925	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
FT669_05930	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FT669_05945	COG0561	phosphatase activity
FT669_05980	COG1309	transcriptional regulator
FT669_05985	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FT669_05995	COG4191	Histidine kinase
FT669_05995	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FT669_06030	COG0745	RESPONSE REGULATOR receiver
FT669_06035	COG2814	Major facilitator Superfamily
FT669_06050	COG3977	Valine--pyruvate aminotransferase
FT669_06055	COG0071	Belongs to the small heat shock protein (HSP20) family
FT669_06060	COG0071	Belongs to the small heat shock protein (HSP20) family
FT669_06065	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
FT669_06075	COG2378	regulation of single-species biofilm formation
FT669_06100	COG0592	DNA-directed DNA polymerase activity
FT669_06105	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
FT669_06125	COG0230	Belongs to the bacterial ribosomal protein bL34 family
FT669_06130	COG0594	ribonuclease P activity
FT669_06135	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
FT669_06140	COG0706	membrane insertase activity
FT669_06150	COG3385	transposase activity
FT669_06155	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
FT669_06160	COG0445	tRNA wobble uridine modification
FT669_06165	COG0357	Ribosomal RNA small subunit methyltransferase G
FT669_06170	COG1192	Involved in chromosome partitioning
FT669_06175	COG1475	DNA binding
FT669_06185	COG0356	it plays a direct role in the translocation of protons across the membrane
FT669_06195	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
FT669_06200	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
FT669_06205	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
FT669_06210	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
FT669_06215	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
FT669_06220	COG0355	proton-transporting ATP synthase activity, rotational mechanism
FT669_06225	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
FT669_06230	COG4452	Inner membrane protein CreD
FT669_06245	COG2205	protein histidine kinase activity
FT669_06250	COG0745	RESPONSE REGULATOR receiver
FT669_06255	COG1349	DNA-binding transcription factor activity
FT669_06260	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
FT669_06265	COG2771	luxR family
FT669_06275	COG0811	peptide transport
FT669_06280	COG0811	peptide transport
FT669_06285	COG0848	biopolymer transport protein
FT669_06290	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
FT669_06330	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
FT669_06335	COG0402	S-adenosylhomocysteine deaminase activity
FT669_06345	COG2226	methyltransferase
FT669_06355	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
FT669_06365	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
FT669_06370	COG0805	protein transport
FT669_06375	COG0084	hydrolase, TatD family'
FT669_06405	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FT669_06410	COG0742	ribosomal rna small subunit methyltransferase
FT669_06420	COG0248	Ppx GppA phosphatase
FT669_06425	COG0513	Belongs to the DEAD box helicase family
FT669_06430	COG3118	belongs to the thioredoxin family
FT669_06445	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
FT669_06460	COG2960	long-chain fatty acid transporting porin activity
FT669_06475	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FT669_06520	COG2202	Pas domain
FT669_06520	COG2199	diguanylate cyclase activity
FT669_06520	COG2200	EAL domain
FT669_06530	COG0751	glycine-tRNA ligase activity
FT669_06535	COG0752	glycyl-tRNA synthetase alpha subunit
FT669_06540	COG2818	Glycosylase
FT669_06550	COG2885	chlorophyll binding
FT669_06555	COG0251	oxidation-reduction process
FT669_06560	COG0425	Belongs to the sulfur carrier protein TusA family
FT669_06595	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FT669_06600	COG0006	proline dipeptidase activity
FT669_06605	COG1739	Uncharacterized protein family UPF0029
FT669_06615	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
FT669_06665	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
FT669_06670	COG0166	Belongs to the GPI family
FT669_06675	COG0668	transmembrane transport
FT669_06680	COG1309	transcriptional regulator
FT669_06690	COG0756	dUTP diphosphatase activity
FT669_06730	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
FT669_06735	COG2003	Belongs to the UPF0758 family
FT669_06740	COG0227	Belongs to the bacterial ribosomal protein bL28 family
FT669_06745	COG0267	Belongs to the bacterial ribosomal protein bL33 family
FT669_06755	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
FT669_06760	COG2990	Protein conserved in bacteria
FT669_06765	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
FT669_06770	COG0859	PFAM glycosyl transferase family 9
FT669_06775	COG0463	Glycosyl transferase, family 2
FT669_06780	COG0859	PFAM glycosyl transferase family 9
FT669_06785	COG1519	Transferase
FT669_06800	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FT669_06805	COG1609	Transcriptional regulator
FT669_06830	COG1580	Controls the rotational direction of flagella during chemotaxis
FT669_06835	COG3161	chorismate lyase activity
FT669_06845	COG3385	transposase activity
FT669_06850	COG2937	Belongs to the GPAT DAPAT family
FT669_06855	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
FT669_06875	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
FT669_06880	COG2205	protein histidine kinase activity
FT669_06885	COG0745	RESPONSE REGULATOR receiver
FT669_06895	COG1045	serine acetyltransferase
FT669_06905	COG3074	FtsZ-dependent cytokinesis
FT669_06915	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FT669_06915	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FT669_06920	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
FT669_06960	COG1609	Transcriptional regulator
FT669_06965	COG3250	beta-galactosidase activity
FT669_06970	COG2731	YhcH YjgK YiaL family protein
FT669_06975	COG0531	amino acid
FT669_06980	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FT669_07035	COG0583	DNA-binding transcription factor activity
FT669_07045	COG3188	usher protein
FT669_07050	COG3121	Chaperone
FT669_07055	COG3539	Fimbrial protein
FT669_07065	COG1561	YicC-like family, N-terminal region
FT669_07070	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
FT669_07075	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
FT669_07090	COG5001	Diguanylate cyclase
FT669_07090	COG4251	negative regulation of phosphorylation
FT669_07090	COG3706	GGDEF domain
FT669_07090	COG2203	Gaf domain
FT669_07095	COG3084	Protein conserved in bacteria
FT669_07105	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
FT669_07110	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
FT669_07135	COG0204	Acyl-transferase
FT669_07140	COG0204	Acyl-transferase
FT669_07160	COG3978	acetolactate synthase activity
FT669_07170	COG0129	dihydroxy-acid dehydratase activity
FT669_07195	COG2391	methyltransferase activity
FT669_07210	COG1012	belongs to the aldehyde dehydrogenase family
FT669_07230	COG0519	Catalyzes the synthesis of GMP from XMP
FT669_07230	COG0518	GMP synthase (glutamine-hydrolyzing) activity
FT669_07235	COG0583	DNA-binding transcription factor activity
FT669_07240	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FT669_07260	COG1322	Protein conserved in bacteria
FT669_07265	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
FT669_07285	COG0174	glutamine synthetase
FT669_07290	COG1217	gtp-binding protein TYPA
FT669_07295	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
FT669_07300	COG0569	domain protein
FT669_07305	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
FT669_07305	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
FT669_07310	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
FT669_07315	COG0242	peptide deformylase activity
FT669_07325	COG0758	DNA mediated transformation
FT669_07330	COG2922	Belongs to the Smg family
FT669_07335	COG0551	DNA topoisomerase type I activity
FT669_07345	COG0009	L-threonylcarbamoyladenylate synthase
FT669_07350	COG0408	coproporphyrinogen oxidase activity
FT669_07365	COG0218	Necessary for normal cell division and for the maintenance of normal septation
FT669_07380	COG3078	GTPase activator activity
FT669_07415	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
FT669_07420	COG1288	antiporter activity
FT669_07425	COG3385	transposase activity
FT669_07430	COG1438	arginine binding
FT669_07435	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
FT669_07440	COG0540	Belongs to the ATCase OTCase family
FT669_07465	COG0583	DNA-binding transcription factor activity
FT669_07485	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
FT669_07500	COG3040	lipid binding
FT669_07510	COG1979	alcohol dehydrogenase
FT669_07515	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
FT669_07520	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
FT669_07530	COG3681	Belongs to the UPF0597 family
FT669_07540	COG0446	pyridine nucleotide-disulphide oxidoreductase
FT669_07550	COG2076	Multidrug Resistance protein
FT669_07555	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
FT669_07570	COG0463	Glycosyl transferase, family 2
FT669_07595	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FT669_07600	COG0564	pseudouridine synthase activity
FT669_07610	COG0542	response to heat
FT669_07620	COG2502	aspartate--ammonia ligase
FT669_07625	COG1522	sequence-specific DNA binding
FT669_07680	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
FT669_07685	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
FT669_07715	COG0243	molybdopterin cofactor binding
FT669_07720	COG3005	denitrification pathway
FT669_07725	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FT669_07725	COG4191	Histidine kinase
FT669_07735	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
FT669_07740	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
FT669_07745	COG0569	domain protein
FT669_07750	COG0812	UDP-N-acetylmuramate dehydrogenase activity
FT669_07780	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
FT669_07795	COG0250	Participates in transcription elongation, termination and antitermination
FT669_07800	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
FT669_07805	COG0081	regulation of translation
FT669_07810	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
FT669_07815	COG0222	ribosome binding
FT669_07825	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
FT669_07830	COG2964	Protein conserved in bacteria
FT669_07840	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
FT669_07845	COG2923	Belongs to the DsrF TusC family
FT669_07850	COG2168	tRNA wobble position uridine thiolation
FT669_07855	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
FT669_07860	COG0049	tRNA binding
FT669_07865	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
FT669_07870	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
FT669_07875	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
FT669_07930	COG3714	YhhN family
FT669_07975	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
FT669_07990	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FT669_08020	COG4221	oxidoreductase activity
FT669_08025	COG0583	DNA-binding transcription factor activity
FT669_08030	COG2249	NAD(P)H dehydrogenase (quinone) activity
FT669_08055	COG0742	ribosomal rna small subunit methyltransferase
FT669_08060	COG0552	protein localization to endoplasmic reticulum
FT669_08065	COG2884	Cell division ATP-binding protein ftsE
FT669_08070	COG2177	Part of the ABC transporter FtsEX involved in
FT669_08080	COG0288	reversible hydration of carbon dioxide
FT669_08085	COG2188	Transcriptional regulator
FT669_08090	COG1228	amidohydrolase
FT669_08100	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
FT669_08105	COG2986	histidine ammonia-lyase
FT669_08110	COG0387	Pfam Sodium calcium exchanger
FT669_08120	COG2200	EAL domain
FT669_08125	COG2200	EAL domain
FT669_08125	COG2199	diguanylate cyclase activity
FT669_08170	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
FT669_08175	COG1459	type II secretion system
FT669_08190	COG2165	general secretion pathway protein
FT669_08195	COG4968	Prepilin-type N-terminal cleavage methylation domain
FT669_08220	COG1077	Cell shape determining protein MreB Mrl
FT669_08225	COG1792	Involved in formation and maintenance of cell shape
FT669_08230	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
FT669_08235	COG0424	maF-like protein
FT669_08255	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FT669_08260	COG0312	modulator of DNA gyrase
FT669_08275	COG0477	Major facilitator Superfamily
FT669_08315	COG1410	methionine synthase
FT669_08315	COG0646	methionine synthase
FT669_08320	COG0189	ligase activity
FT669_08325	COG0642	Histidine kinase
FT669_08330	COG0745	RESPONSE REGULATOR receiver
FT669_08350	COG0789	Transcriptional regulator
FT669_08355	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
FT669_08360	COG0352	thiamine-phosphate diphosphorylase activity
FT669_08365	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
FT669_08375	COG2022	thiamine diphosphate biosynthetic process
FT669_08410	COG0814	amino acid
FT669_08415	COG3932	Exopolysaccharide synthesis, ExoD
FT669_08430	COG0004	ammonium transporteR
FT669_08435	COG3133	Outer membrane lipoprotein
FT669_08440	COG0456	acetyltransferase
FT669_08465	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
FT669_08470	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
FT669_08490	COG0628	permease
FT669_08505	COG3284	Transcriptional regulator
FT669_08515	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
FT669_08515	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
FT669_08515	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
FT669_08520	COG1461	Dihydroxyacetone kinase
FT669_08525	COG2376	Dihydroxyacetone kinase
FT669_08530	COG2252	PERMEase
FT669_08555	COG0629	single-stranded DNA binding
FT669_08580	COG0840	transmembrane signaling receptor activity
FT669_08605	COG3135	benzoate transporter
FT669_08610	COG1396	sequence-specific DNA binding
FT669_08650	COG2926	Belongs to the UPF0265 family
FT669_08660	COG0561	phosphatase activity
FT669_08670	COG1546	Belongs to the CinA family
FT669_08670	COG1058	Belongs to the CinA family
FT669_08675	COG1418	mRNA catabolic process
FT669_08680	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
FT669_08690	COG1522	sequence-specific DNA binding
FT669_08695	COG1368	sulfuric ester hydrolase activity
FT669_08720	COG1285	pathogenesis
FT669_08740	COG4221	oxidoreductase activity
FT669_08755	COG1979	alcohol dehydrogenase
FT669_08760	COG1803	Methylglyoxal synthase
FT669_08780	COG1444	tRNA N-acetyltransferase activity
FT669_08790	COG0784	Response regulator, receiver
FT669_08790	COG0835	chemotaxis
FT669_08795	COG2949	membrane
FT669_08800	COG3291	Pkd domain containing protein
FT669_08835	COG3539	Fimbrial protein
FT669_08855	COG0318	PFAM AMP-dependent synthetase and ligase
FT669_08865	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
FT669_08870	COG0596	Alpha beta hydrolase
FT669_08885	COG1575	Belongs to the MenA family. Type 1 subfamily
FT669_08905	COG0513	Belongs to the DEAD box helicase family
FT669_08910	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
FT669_08915	COG1988	membrane-bound metal-dependent
FT669_08955	COG3722	fumarate hydratase activity
FT669_08960	COG0246	Mannitol dehydrogenase
FT669_08965	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
FT669_08965	COG2213	PTS system mannitol-specific
FT669_08975	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
FT669_08975	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
FT669_08980	COG1538	Outer membrane efflux protein
FT669_08985	COG0494	nUDIX hydrolase
FT669_08990	COG3151	Protein conserved in bacteria
FT669_09000	COG3150	esterase
FT669_09005	COG1051	belongs to the nudix hydrolase family
FT669_09020	COG1566	PFAM secretion protein HlyD family protein
FT669_09030	COG0187	DNA topoisomerase II activity
FT669_09045	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
FT669_09085	COG2084	Dehydrogenase
FT669_09095	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FT669_09115	COG0204	Acyl-transferase
FT669_09125	COG1842	Phage shock protein A
FT669_09140	COG2827	Endonuclease containing a URI domain
FT669_09155	COG1573	uracil-dna glycosylase
FT669_09160	COG0697	spore germination
FT669_09165	COG0583	DNA-binding transcription factor activity
FT669_09170	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FT669_09175	COG1121	(ABC) transporter
FT669_09180	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
FT669_09200	COG0739	heme binding
FT669_09210	COG3068	Protein conserved in bacteria
FT669_09230	COG0617	tRNA 3'-terminal CCA addition
FT669_09235	COG1194	a g-specific adenine glycosylase
FT669_09240	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
FT669_09265	COG3706	GGDEF domain
FT669_09270	COG0557	exoribonuclease II activity
FT669_09275	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FT669_09285	COG2153	protein acetylation
FT669_09290	COG0513	Belongs to the DEAD box helicase family
FT669_09320	COG0735	belongs to the Fur family
FT669_09325	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
FT669_09335	COG4166	transmembrane transport
FT669_09345	COG0110	maltose O-acetyltransferase activity
FT669_09355	COG1024	Enoyl-CoA hydratase
FT669_09370	COG4221	oxidoreductase activity
FT669_09375	COG0442	prolyl-tRNA aminoacylation
FT669_09380	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
FT669_09385	COG3009	Protein conserved in bacteria
FT669_09390	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
FT669_09390	COG3008	intermembrane lipid transfer
FT669_09395	COG2995	paraquat-inducible protein a
FT669_09415	COG2203	Gaf domain
FT669_09415	COG5001	Diguanylate cyclase
FT669_09415	COG4251	negative regulation of phosphorylation
FT669_09415	COG3706	GGDEF domain
FT669_09420	COG4776	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction
FT669_09435	COG2771	luxR family
FT669_09445	COG0840	transmembrane signaling receptor activity
FT669_09450	COG0632	four-way junction helicase activity
FT669_09460	COG1271	oxidase subunit
FT669_09465	COG1294	oxidase, subunit
FT669_09470	COG4890	Cyd operon protein YbgT
FT669_09475	COG3790	cyd operon protein YbgE
FT669_09480	COG0824	Thioesterase
FT669_09485	COG0811	peptide transport
FT669_09500	COG0823	Involved in the tonB-independent uptake of proteins
FT669_09505	COG2885	chlorophyll binding
FT669_09510	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
FT669_09575	COG0733	neurotransmitter:sodium symporter activity
FT669_09585	COG0733	neurotransmitter:sodium symporter activity
FT669_09600	COG0561	phosphatase activity
FT669_09625	COG1051	belongs to the nudix hydrolase family
FT669_09645	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
FT669_09655	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
FT669_09665	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
FT669_09670	COG0840	transmembrane signaling receptor activity
FT669_09675	COG1585	Membrane protein implicated in regulation of membrane protease activity
FT669_09680	COG0330	HflC and HflK could
FT669_09690	COG0175	sulfate reduction
FT669_09695	COG2895	sulfate adenylyltransferase (ATP) activity
FT669_09700	COG0529	Catalyzes the synthesis of activated sulfate
FT669_09715	COG0840	transmembrane signaling receptor activity
FT669_09750	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
FT669_09765	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
FT669_09780	COG2076	Multidrug Resistance protein
FT669_09785	COG2076	Multidrug Resistance protein
FT669_09790	COG0346	lactoylglutathione lyase activity
FT669_09795	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FT669_09800	COG1643	Atp-dependent helicase
FT669_09810	COG1489	DNA binding
FT669_09815	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
FT669_09830	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
FT669_09840	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
FT669_09850	COG1823	symporter activity
FT669_09870	COG1924	4 iron, 4 sulfur cluster binding
FT669_09875	COG1775	2-hydroxyglutaryl-CoA dehydratase, D-component
FT669_09880	COG0842	Transport permease protein
FT669_09885	COG1131	(ABC) transporter
FT669_09900	COG0163	prenyltransferase activity
FT669_09910	COG0671	phosphoesterase, PA-phosphatase related
FT669_09915	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
FT669_09920	COG1017	nitric oxide dioxygenase activity
FT669_09920	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
FT669_09925	COG1151	hydroxylamine reductase activity
FT669_09930	COG0783	Belongs to the Dps family
FT669_09935	COG3023	N-Acetylmuramoyl-L-alanine amidase
FT669_09940	COG4807	Protein conserved in bacteria
FT669_09950	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
FT669_09955	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
FT669_09960	COG3956	TIGRFAM MazG family protein
FT669_09965	COG0504	CTP synthase activity
FT669_09970	COG0148	phosphopyruvate hydratase activity
FT669_10005	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
FT669_10015	COG0488	(ABC) transporter
FT669_10020	COG0517	IMP dehydrogenase activity
FT669_10035	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FT669_10050	COG1794	racemase activity, acting on amino acids and derivatives
FT669_10060	COG2731	YhcH YjgK YiaL family protein
FT669_10075	COG1376	ErfK ybiS ycfS ynhG family protein
FT669_10085	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FT669_10090	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
FT669_10110	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
FT669_10115	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
FT669_10120	COG1238	metal cluster binding
FT669_10135	COG1902	pentaerythritol trinitrate reductase activity
FT669_10150	COG2957	Belongs to the agmatine deiminase family
FT669_10170	COG0471	metal ion transport
FT669_10175	COG0513	Belongs to the DEAD box helicase family
FT669_10180	COG2203	Gaf domain
FT669_10180	COG2199	diguanylate cyclase activity
FT669_10190	COG1912	Pfam S-adenosyl-l-methionine hydroxide adenosyltransferase
FT669_10240	COG4191	Histidine kinase
FT669_10265	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
FT669_10275	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FT669_10280	COG4991	sh3 domain protein
FT669_10290	COG2816	NAD+ diphosphatase activity
FT669_10300	COG1940	carbohydrate kinase activity
FT669_10305	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
FT669_10310	COG0126	phosphoglycerate kinase activity
FT669_10320	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FT669_10365	COG0354	folic acid binding
FT669_10380	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
FT669_10385	COG1595	DNA-templated transcription, initiation
FT669_10390	COG3073	An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E
FT669_10395	COG3026	antisigma factor binding
FT669_10405	COG0481	GTPase activity
FT669_10410	COG0681	Belongs to the peptidase S26 family
FT669_10425	COG1381	Involved in DNA repair and RecF pathway recombination
FT669_10430	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
FT669_10440	COG2350	Protein conserved in bacteria
FT669_10445	COG2917	probably involved in intracellular septation
FT669_10450	COG0076	glutamate decarboxylase activity
FT669_10460	COG0569	domain protein
FT669_10460	COG2985	domain, Protein
FT669_10490	COG3076	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome
FT669_10510	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FT669_10515	COG1028	Short-chain dehydrogenase reductase Sdr
FT669_10520	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
FT669_10525	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FT669_10550	COG2986	histidine ammonia-lyase
FT669_10560	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
FT669_10575	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FT669_10610	COG2313	pseudouridylate synthase activity
FT669_10615	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FT669_10660	COG1765	OsmC-like protein
FT669_10675	COG3954	Phosphoribulokinase
FT669_10680	COG3089	Belongs to the UPF0270 family
FT669_10685	COG2203	Gaf domain
FT669_10685	COG5001	Diguanylate cyclase
FT669_10685	COG4251	negative regulation of phosphorylation
FT669_10685	COG3706	GGDEF domain
FT669_10690	COG0429	hydrolase of the alpha beta-hydrolase fold
FT669_10695	COG0835	chemotaxis
FT669_10695	COG0784	Response regulator, receiver
FT669_10705	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
FT669_10710	COG1047	Peptidyl-prolyl cis-trans
FT669_10725	COG0545	Peptidyl-prolyl cis-trans isomerase
FT669_10730	COG2204	response regulator
FT669_10750	COG0737	Belongs to the 5'-nucleotidase family
FT669_10765	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
FT669_10780	COG1966	Carbon starvation protein
FT669_10805	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FT669_10815	COG3721	Heme iron utilization protein
FT669_10820	COG0748	coenzyme F420 binding
FT669_10845	COG2771	luxR family
FT669_10855	COG3501	Rhs element vgr protein
FT669_10880	COG2814	Major facilitator Superfamily
FT669_10885	COG0784	Response regulator, receiver
FT669_10885	COG2205	protein histidine kinase activity
FT669_10885	COG5002	protein histidine kinase activity
FT669_10950	COG0835	chemotaxis
FT669_10950	COG0784	Response regulator, receiver
FT669_10960	COG4181	ATPase activity
FT669_10970	COG1090	epimerase
FT669_10975	COG2200	EAL domain
FT669_10980	COG3385	transposase activity
FT669_10995	COG3171	Protein conserved in bacteria
FT669_11005	COG2897	thiosulfate sulfurtransferase activity
FT669_11010	COG3385	transposase activity
FT669_11025	COG0521	Mo-molybdopterin cofactor biosynthetic process
FT669_11035	COG2966	Psort location CytoplasmicMembrane, score
FT669_11040	COG3610	response to peptide
FT669_11055	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FT669_11065	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
FT669_11080	COG0786	glutamate:sodium symporter activity
FT669_11085	COG0252	asparaginase activity
FT669_11090	COG3139	Protein of unknown function (DUF1315)
FT669_11115	COG0321	lipoyl(octanoyl) transferase activity
FT669_11120	COG2921	Belongs to the UPF0250 family
FT669_11125	COG1686	Belongs to the peptidase S11 family
FT669_11130	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
FT669_11135	COG2951	lytic endotransglycosylase activity
FT669_11140	COG0772	Belongs to the SEDS family
FT669_11145	COG0768	penicillin binding
FT669_11155	COG0799	negative regulation of ribosome biogenesis
FT669_11175	COG0495	leucyl-tRNA aminoacylation
FT669_11190	COG0312	modulator of DNA gyrase
FT669_11200	COG0716	FMN binding
FT669_11205	COG4974	Belongs to the 'phage' integrase family
FT669_11215	COG1970	mechanosensitive ion channel activity
FT669_11240	COG0815	Transfers the fatty acyl group on membrane lipoproteins
FT669_11245	COG4535	Mg2 and Co2 transporter CorC
FT669_11250	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
FT669_11260	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
FT669_11270	COG1335	isochorismatase
FT669_11280	COG3706	GGDEF domain
FT669_11305	COG3069	C4-dicarboxylate transmembrane transporter activity
FT669_11320	COG0583	DNA-binding transcription factor activity
FT669_11340	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
FT669_11350	COG0516	GMP reductase activity
FT669_11375	COG1028	Short-chain dehydrogenase reductase Sdr
FT669_11385	COG0318	PFAM AMP-dependent synthetase and ligase
FT669_11400	COG3385	transposase activity
FT669_11405	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FT669_11420	COG3214	Protein conserved in bacteria
FT669_11440	COG3366	ferrous iron transmembrane transporter activity
FT669_11450	COG3029	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
FT669_11455	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
FT669_11460	COG1053	succinate dehydrogenase
FT669_11470	COG0584	glycerophosphoryl diester phosphodiesterase
FT669_11475	COG1511	domain protein
FT669_11475	COG3264	Mechanosensitive ion channel
FT669_11485	COG0739	heme binding
FT669_11515	COG0583	DNA-binding transcription factor activity
FT669_11520	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
FT669_11550	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
FT669_11555	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
FT669_11565	COG0338	D12 class N6 adenine-specific DNA methyltransferase
FT669_11570	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
FT669_11580	COG0180	Tryptophanyl-tRNA synthetase
FT669_11590	COG0512	Glutamine amidotransferase of anthranilate synthase
FT669_11605	COG1012	belongs to the aldehyde dehydrogenase family
FT669_11620	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FT669_11635	COG0366	Alpha amylase catalytic
FT669_11655	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
FT669_11665	COG0490	domain, Protein
FT669_11665	COG0471	metal ion transport
FT669_11715	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
FT669_11720	COG3842	ATPase activity
FT669_11725	COG1176	ABC-type spermidine putrescine transport system, permease component I
FT669_11730	COG1177	transmembrane transport
FT669_11735	COG1012	belongs to the aldehyde dehydrogenase family
FT669_11765	COG0328	RNA-DNA hybrid ribonuclease activity
FT669_11810	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
FT669_11855	COG0012	GTP binding
FT669_11860	COG0193	aminoacyl-tRNA hydrolase activity
FT669_11870	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
FT669_11880	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
FT669_11885	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
FT669_11895	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
FT669_11900	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
FT669_11905	COG2890	protein-(glutamine-N5) methyltransferase activity
FT669_11915	COG2912	Transglutaminase-like superfamily
FT669_11920	COG2877	3-deoxy-8-phosphooctulonate synthase activity
FT669_11925	COG1301	dicarboxylic acid transport
FT669_11940	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
FT669_11950	COG3385	transposase activity
FT669_11965	COG1881	PFAM PEBP family protein
FT669_11970	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
FT669_12000	COG1028	Short-chain dehydrogenase reductase Sdr
FT669_12005	COG0616	signal peptide processing
FT669_12010	COG2211	Major facilitator Superfamily
FT669_12015	COG2199	diguanylate cyclase activity
FT669_12015	COG2203	Gaf domain
FT669_12020	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
FT669_12030	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
FT669_12035	COG0826	peptidase U32
FT669_12040	COG2203	Gaf domain
FT669_12040	COG2200	EAL domain
FT669_12040	COG2199	diguanylate cyclase activity
FT669_12045	COG2197	response regulator
FT669_12050	COG5002	protein histidine kinase activity
FT669_12050	COG2205	protein histidine kinase activity
FT669_12050	COG0784	Response regulator, receiver
FT669_12075	COG3724	N-succinylarginine dihydrolase activity
FT669_12105	COG4608	Belongs to the ABC transporter superfamily
FT669_12110	COG0444	Belongs to the ABC transporter superfamily
FT669_12120	COG0601	transmembrane transport
FT669_12170	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
FT669_12175	COG1289	transmembrane transporter activity
FT669_12190	COG1136	(ABC) transporter
FT669_12195	COG4662	Binding-protein-dependent transport system inner membrane component
FT669_12220	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
FT669_12260	COG0437	4 iron, 4 sulfur cluster binding
FT669_12270	COG3385	transposase activity
FT669_12275	COG0745	RESPONSE REGULATOR receiver
FT669_12280	COG0281	malic enzyme
FT669_12305	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FT669_12350	COG1737	Transcriptional regulator
FT669_12355	COG0469	pyruvate kinase activity
FT669_12365	COG1677	Flagellar hook-basal body complex protein FliE
FT669_12375	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
FT669_12430	COG1684	flagellar biosynthetic protein fliR
FT669_12440	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
FT669_12465	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
FT669_12475	COG2201	protein-glutamate methylesterase activity
FT669_12480	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
FT669_12485	COG1360	Flagellar Motor Protein
FT669_12490	COG1192	Involved in chromosome partitioning
FT669_12500	COG0835	chemotaxis
FT669_12515	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
FT669_12520	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
FT669_12525	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
FT669_12530	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
FT669_12535	COG1138	Cytochrome C-type biogenesis protein
FT669_12540	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FT669_12550	COG4235	cytochrome complex assembly
FT669_12550	COG3088	subunit of a heme lyase
FT669_12565	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
FT669_12580	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
FT669_12585	COG1882	Formate acetyltransferase
FT669_12595	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
FT669_12595	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
FT669_12610	COG0259	pyridoxamine-phosphate oxidase activity
FT669_12615	COG0625	glutathione transferase activity
FT669_12655	COG2850	peptidyl-arginine hydroxylation
FT669_12660	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
FT669_12665	COG2915	High frequency lysogenization protein hflD homolog
FT669_12670	COG0482	sulfurtransferase activity
FT669_12675	COG1051	belongs to the nudix hydrolase family
FT669_12680	COG1187	pseudouridine synthase activity
FT669_12690	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FT669_12710	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FT669_12710	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FT669_12710	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FT669_12725	COG4821	SIS domain
FT669_12735	COG1609	Transcriptional regulator
FT669_12740	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FT669_12740	COG1263	PTS System
FT669_12745	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
FT669_12770	COG4792	protein secretion
FT669_12780	COG4794	Type iii secretion
FT669_12945	COG1317	bacterial-type flagellum organization
FT669_12960	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
FT669_12965	COG1960	acyl-CoA dehydrogenase activity
FT669_12975	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
FT669_12985	COG3383	formate dehydrogenase (NAD+) activity
FT669_12990	COG1940	carbohydrate kinase activity
FT669_12995	COG0457	Tetratricopeptide repeat
FT669_13000	COG2814	Major facilitator Superfamily
FT669_13000	COG0477	Major facilitator Superfamily
FT669_13065	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
FT669_13070	COG2867	negative regulation of translational initiation
FT669_13075	COG2914	Belongs to the UPF0125 (RnfH) family
FT669_13090	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
FT669_13095	COG0121	glutamine amidotransferase
FT669_13125	COG2197	response regulator
FT669_13130	COG3850	Histidine kinase
FT669_13135	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
FT669_13140	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
FT669_13150	COG0243	molybdopterin cofactor binding
FT669_13155	COG0437	4 iron, 4 sulfur cluster binding
FT669_13170	COG3005	denitrification pathway
FT669_13175	COG0521	Mo-molybdopterin cofactor biosynthetic process
FT669_13180	COG0315	cyclic pyranopterin monophosphate synthase activity
FT669_13185	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
FT669_13190	COG0314	molybdopterin synthase activity
FT669_13205	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
FT669_13225	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
FT669_13230	COG0303	'Molybdopterin
FT669_13235	COG0302	gtp cyclohydrolase
FT669_13240	COG0840	transmembrane signaling receptor activity
FT669_13245	COG2759	Belongs to the formate--tetrahydrofolate ligase family
FT669_13255	COG0583	DNA-binding transcription factor activity
FT669_13300	COG1166	arginine decarboxylase activity
FT669_13305	COG3385	transposase activity
FT669_13320	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
FT669_13340	COG0814	amino acid
FT669_13350	COG3681	Belongs to the UPF0597 family
FT669_13355	COG2964	Protein conserved in bacteria
FT669_13360	COG0406	alpha-ribazole phosphatase activity
FT669_13375	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
FT669_13380	COG1288	antiporter activity
FT669_13395	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
FT669_13400	COG0741	lytic transglycosylase activity
FT669_13400	COG0739	heme binding
FT669_13400	COG1196	nuclear chromosome segregation
FT669_13425	COG0788	formyltetrahydrofolate deformylase activity
FT669_13430	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FT669_13440	COG3118	belongs to the thioredoxin family
FT669_13450	COG0791	NLP P60 protein
FT669_13455	COG3129	Specifically methylates the adenine in position 1618 of 23S rRNA
FT669_13465	COG0471	metal ion transport
FT669_13475	COG1388	LysM domain
FT669_13475	COG1376	ErfK ybiS ycfS ynhG family protein
FT669_13525	COG0582	viral genome integration into host DNA
FT669_13550	COG1388	LysM domain
FT669_13550	COG0741	lytic transglycosylase activity
FT669_13555	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FT669_13560	COG2226	methyltransferase
FT669_13565	COG0328	RNA-DNA hybrid ribonuclease activity
FT669_13570	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
FT669_13585	COG0784	Response regulator, receiver
FT669_13585	COG3437	response regulator, receiver
FT669_13595	COG2375	cellular response to nickel ion
FT669_13600	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FT669_13650	COG1122	ATPase activity
FT669_13655	COG1122	ATPase activity
FT669_13675	COG0708	Exodeoxyribonuclease III
FT669_13770	COG3132	Protein of unknown function, DUF480
FT669_13775	COG2841	Protein conserved in bacteria
FT669_13785	COG0534	Mate efflux family protein
FT669_13805	COG1454	alcohol dehydrogenase
FT669_13815	COG1309	transcriptional regulator
FT669_13850	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
FT669_13860	COG1845	cytochrome c oxidase, subunit III
FT669_13865	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
FT669_13870	COG0109	protoheme IX farnesyltransferase activity
FT669_13880	COG3152	Membrane
FT669_13885	COG2175	clavaminate synthase activity
FT669_13890	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FT669_13895	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
FT669_13900	COG4521	taurine ABC transporter
FT669_13915	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FT669_13935	COG2207	Transcriptional regulator
FT669_13940	COG0538	isocitrate dehydrogenase activity
FT669_13945	COG3048	D-serine ammonia-lyase activity
FT669_13950	COG2610	gluconate transmembrane transporter activity
FT669_13955	COG0583	DNA-binding transcription factor activity
FT669_13965	COG0791	NLP P60 protein
FT669_13970	COG0583	DNA-binding transcription factor activity
FT669_13975	COG0450	alkyl hydroperoxide reductase
FT669_13980	COG3385	transposase activity
FT669_14000	COG0500	methyltransferase
FT669_14005	COG4106	trans-aconitate 2-methyltransferase activity
FT669_14010	COG1801	Protein of unknown function DUF72
FT669_14020	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
FT669_14025	COG0217	transcriptional regulatory protein
FT669_14030	COG2194	sulfuric ester hydrolase activity
FT669_14040	COG1454	alcohol dehydrogenase
FT669_14040	COG1012	belongs to the aldehyde dehydrogenase family
FT669_14045	COG2095	MarC family integral membrane protein
FT669_14060	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FT669_14075	COG0861	Integral membrane protein TerC family
FT669_14080	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
FT669_14085	COG2020	methyltransferase activity
FT669_14110	COG4138	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system
FT669_14115	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
FT669_14125	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FT669_14130	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
FT669_14135	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
FT669_14145	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
FT669_14150	COG0505	Belongs to the CarA family
FT669_14155	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
FT669_14170	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
FT669_14185	COG0346	lactoylglutathione lyase activity
FT669_14190	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
FT669_14200	COG4659	FMN binding
FT669_14205	COG4658	electron transport chain
FT669_14215	COG2878	Part of a membrane complex involved in electron transport
FT669_14220	COG4657	Part of a membrane complex involved in electron transport
FT669_14245	COG0346	lactoylglutathione lyase activity
FT669_14250	COG1187	pseudouridine synthase activity
FT669_14255	COG2807	transmembrane transport
FT669_14290	COG2979	Protein of unknown function (DUF533)
FT669_14325	COG3220	belongs to the UPF0276 family
FT669_14340	COG2249	NAD(P)H dehydrogenase (quinone) activity
FT669_14365	COG0693	protein deglycase activity
FT669_14370	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FT669_14390	COG0583	DNA-binding transcription factor activity
FT669_14400	COG0840	transmembrane signaling receptor activity
FT669_14405	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
FT669_14410	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
FT669_14415	COG2271	Major facilitator Superfamily
FT669_14420	COG1349	DNA-binding transcription factor activity
FT669_14430	COG0584	glycerophosphoryl diester phosphodiesterase
FT669_14435	COG4574	serine-type endopeptidase inhibitor activity
FT669_14440	COG3085	chromosome segregation
FT669_14445	COG0583	DNA-binding transcription factor activity
FT669_14455	COG1448	Aminotransferase
FT669_14470	COG0658	competence protein
FT669_14470	COG2333	competence protein COMEC
FT669_14480	COG1663	tetraacyldisaccharide 4'-kinase activity
FT669_14485	COG2835	tetraacyldisaccharide 4'-kinase activity
FT669_14490	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
FT669_14495	COG2197	response regulator
FT669_14545	COG0642	Histidine kinase
FT669_14550	COG2261	transglycosylase associated protein
FT669_14555	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FT669_14565	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
FT669_14570	COG0215	cysteine-tRNA ligase activity
FT669_14625	COG2119	membrane
FT669_14630	COG0023	Translation Initiation Factor
FT669_14640	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
FT669_14655	COG0513	Belongs to the DEAD box helicase family
FT669_14660	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
FT669_14675	COG0765	amino acid transport
FT669_14680	COG1126	abc transporter atp-binding protein
FT669_14685	COG0493	'glutamate synthase
FT669_14690	COG0069	glutamate synthase activity
FT669_14690	COG0067	glutamate synthase
FT669_14690	COG0070	glutamate synthase
FT669_14695	COG1242	4 iron, 4 sulfur cluster binding
FT669_14760	COG3634	alkyl hydroperoxide reductase activity
FT669_14770	COG0517	IMP dehydrogenase activity
FT669_14770	COG1125	glycine betaine transport
FT669_14775	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
FT669_14780	COG0343	queuine tRNA-ribosyltransferase activity
FT669_14785	COG1862	Preprotein translocase
FT669_14790	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FT669_14795	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FT669_14810	COG0826	peptidase U32
FT669_14815	COG0826	peptidase U32
FT669_14840	COG1104	cysteine desulfurase activity
FT669_14845	COG0822	iron-sulfur transferase activity
FT669_14855	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
FT669_14860	COG0443	Heat shock 70 kDa protein
FT669_14865	COG0633	Ferredoxin
FT669_14880	COG0105	UTP biosynthetic process
FT669_14885	COG0820	rRNA (adenine-C2-)-methyltransferase activity
FT669_14895	COG1426	Protein conserved in bacteria
FT669_14905	COG0124	histidyl-tRNA synthetase
FT669_14910	COG2976	Protein conserved in bacteria
FT669_14915	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FT669_14920	COG1160	GTP binding
FT669_14925	COG1645	bacterial-type flagellum-dependent swarming motility
FT669_14935	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
FT669_14940	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
FT669_14940	COG0047	phosphoribosylformylglycinamidine synthase activity
FT669_14965	COG3385	transposase activity
FT669_14970	COG1007	ATP synthesis coupled electron transport
FT669_14975	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FT669_14985	COG0713	ATP synthesis coupled electron transport
FT669_14990	COG0839	Belongs to the complex I subunit 6 family
FT669_14995	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FT669_15005	COG1034	ATP synthesis coupled electron transport
FT669_15020	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FT669_15020	COG0649	NAD binding
FT669_15030	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FT669_15040	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
FT669_15080	COG0765	amino acid transport
FT669_15085	COG1126	abc transporter atp-binding protein
FT669_15095	COG0724	RNA recognition motif
FT669_15100	COG4989	oxidoreductase activity
FT669_15125	COG3437	response regulator, receiver
FT669_15135	COG5001	Diguanylate cyclase
FT669_15135	COG3300	MHYT domain
FT669_15160	COG2814	Major facilitator Superfamily
FT669_15170	COG0583	DNA-binding transcription factor activity
FT669_15175	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FT669_15180	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
FT669_15185	COG0539	negative regulation of cytoplasmic translation
FT669_15190	COG0776	regulation of translation
FT669_15200	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
FT669_15220	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
FT669_15225	COG0602	queuosine metabolic process
FT669_15230	COG3530	Putative quorum-sensing-regulated virulence factor
FT669_15235	COG2096	Adenosyltransferase
FT669_15240	COG2916	Histone family protein nucleoid-structuring protein H-NS
FT669_15245	COG1757	Na H antiporter
FT669_15250	COG1435	thymidine kinase activity
FT669_15270	COG2205	protein histidine kinase activity
FT669_15270	COG0784	Response regulator, receiver
FT669_15310	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
FT669_15320	COG0438	transferase activity, transferring glycosyl groups
FT669_15375	COG0438	transferase activity, transferring glycosyl groups
FT669_15395	COG0297	glycogen (starch) synthase activity
FT669_15420	COG3385	transposase activity
FT669_15430	COG2194	sulfuric ester hydrolase activity
FT669_15455	COG2205	protein histidine kinase activity
FT669_15480	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
FT669_15485	COG1278	Cold shock
FT669_15490	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
FT669_15495	COG0542	response to heat
FT669_15500	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
FT669_15505	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
FT669_15510	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
FT669_15515	COG3134	Outer membrane lipoprotein
FT669_15520	COG3706	GGDEF domain
FT669_15525	COG0492	ferredoxin-NADP+ reductase activity
FT669_15530	COG0686	Belongs to the AlaDH PNT family
FT669_15540	COG1674	ftsk spoiiie
FT669_15540	COG0531	amino acid
FT669_15545	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
FT669_15555	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
FT669_15560	COG1286	toxin biosynthetic process
FT669_15575	COG0563	adenylate kinase activity
FT669_15580	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
FT669_15590	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FT669_15660	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
FT669_15670	COG3385	transposase activity
FT669_15685	COG0513	Belongs to the DEAD box helicase family
FT669_15690	COG0386	Belongs to the glutathione peroxidase family
FT669_15700	COG1181	Belongs to the D-alanine--D-alanine ligase family
FT669_15705	COG0383	alpha-mannosidase activity
FT669_15710	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FT669_15710	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FT669_15710	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FT669_15720	COG1570	exodeoxyribonuclease VII activity
FT669_15740	COG3158	transport of potassium into the cell
FT669_15745	COG0516	GMP reductase activity
FT669_15745	COG0517	IMP dehydrogenase activity
FT669_15750	COG0518	GMP synthase (glutamine-hydrolyzing) activity
FT669_15750	COG0519	Catalyzes the synthesis of GMP from XMP
FT669_15785	COG2062	phosphohistidine phosphatase, SixA
FT669_15805	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
FT669_15820	COG4591	ABC-type transport system involved in lipoprotein release permease component
FT669_15825	COG1136	(ABC) transporter
FT669_15835	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
FT669_15850	COG0544	peptidyl-prolyl cis-trans isomerase activity
FT669_15855	COG0740	serine-type endopeptidase activity
FT669_15860	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
FT669_15865	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
FT669_15870	COG0776	regulation of translation
FT669_15875	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FT669_15880	COG0488	(ABC) transporter
FT669_15885	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FT669_15890	COG3162	membrane
FT669_15905	COG1024	Enoyl-CoA hydratase
FT669_15910	COG1115	amino acid carrier protein
FT669_15920	COG3228	Belongs to the MtfA family
FT669_15925	COG1584	GPR1 FUN34 yaaH family protein
FT669_15955	COG1024	Enoyl-CoA hydratase
FT669_15960	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
FT669_15965	COG1960	acyl-CoA dehydrogenase activity
FT669_15970	COG1960	acyl-CoA dehydrogenase activity
FT669_15975	COG1024	Enoyl-CoA hydratase
FT669_15980	COG1024	Enoyl-CoA hydratase
FT669_15990	COG1028	Short-chain dehydrogenase reductase Sdr
FT669_16050	COG2003	Belongs to the UPF0758 family
FT669_16060	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
FT669_16095	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
FT669_16110	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
FT669_16120	COG1773	rubredoxin
FT669_16130	COG0601	transmembrane transport
FT669_16140	COG0444	Belongs to the ABC transporter superfamily
FT669_16145	COG1124	(ABC) transporter
FT669_16160	COG0375	protein maturation
FT669_16165	COG0309	Hydrogenase expression formation protein (HypE)
FT669_16175	COG0298	carbon dioxide binding
FT669_16180	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
FT669_16190	COG1921	L-seryl-tRNASec selenium transferase activity
FT669_16205	COG3260	NADH ubiquinone oxidoreductase 20
FT669_16215	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
FT669_16215	COG3261	NADH dehydrogenase
FT669_16220	COG0650	Formate hydrogenlyase subunit 4
FT669_16230	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
FT669_16235	COG3158	transport of potassium into the cell
FT669_16255	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
FT669_16280	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
FT669_16295	COG3046	protein related to deoxyribodipyrimidine photolyase
FT669_16310	COG0295	cytidine deaminase activity
FT669_16315	COG1346	cytolysis
FT669_16320	COG1380	Effector of murein hydrolase LrgA
FT669_16335	COG2925	Exonuclease
FT669_16340	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
FT669_16345	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
FT669_16355	COG3437	response regulator, receiver
FT669_16360	COG5002	protein histidine kinase activity
FT669_16360	COG2205	protein histidine kinase activity
FT669_16360	COG0784	Response regulator, receiver
FT669_16365	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
FT669_16370	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
FT669_16370	COG0617	tRNA 3'-terminal CCA addition
FT669_16370	COG0517	IMP dehydrogenase activity
FT669_16375	COG1643	Atp-dependent helicase
FT669_16385	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
FT669_16400	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
FT669_16410	COG2067	long-chain fatty acid transport protein
FT669_16450	COG0714	Associated with various cellular activities
FT669_16465	COG2719	SpoVR family
FT669_16470	COG2718	Belongs to the UPF0229 family
FT669_16475	COG2766	serine protein kinase
FT669_16480	COG0514	ATP-dependent DNA helicase (RecQ)
FT669_16485	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
FT669_16490	COG0814	amino acid
FT669_16510	COG3385	transposase activity
FT669_16515	COG1760	l-serine dehydratase
FT669_16525	COG3123	guanosine phosphorylase activity
FT669_16530	COG1301	dicarboxylic acid transport
FT669_16535	COG0205	6-phosphofructokinase activity
FT669_16545	COG1434	Gram-negative-bacterium-type cell wall biogenesis
FT669_16550	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
FT669_16560	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
FT669_16565	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
FT669_16570	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
FT669_16580	COG0242	peptide deformylase activity
FT669_16600	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
FT669_16605	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
FT669_16610	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FT669_16620	COG0549	Belongs to the carbamate kinase family
FT669_16625	COG0697	spore germination
FT669_16630	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
FT669_16630	COG3608	succinylglutamate desuccinylase aspartoacylase
FT669_16635	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
FT669_16640	COG2068	MobA-Related Protein
FT669_16650	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
FT669_16650	COG0493	'glutamate synthase
FT669_16655	COG0402	S-adenosylhomocysteine deaminase activity
FT669_16670	COG2233	PERMEase
FT669_16675	COG0402	S-adenosylhomocysteine deaminase activity
FT669_16680	COG2252	PERMEase
FT669_16695	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
FT669_16705	COG3134	Outer membrane lipoprotein
FT669_16715	COG0318	PFAM AMP-dependent synthetase and ligase
FT669_16735	COG0107	imidazoleglycerol-phosphate synthase activity
FT669_16745	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
FT669_16750	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
FT669_16750	COG0131	Imidazoleglycerol-phosphate dehydratase
FT669_16765	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
FT669_16780	COG1214	PFAM Peptidase M22, glycoprotease
FT669_16795	COG0318	PFAM AMP-dependent synthetase and ligase
FT669_16810	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
FT669_16815	COG0709	Synthesizes selenophosphate from selenide and ATP
FT669_16825	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
FT669_16830	COG0840	transmembrane signaling receptor activity
FT669_16845	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FT669_16845	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FT669_16850	COG0489	protein tyrosine kinase activity
FT669_16855	COG0572	uridine kinase
FT669_16860	COG0717	Belongs to the dCTP deaminase family
FT669_16865	COG0306	phosphate transporter
FT669_16875	COG1530	ribonuclease E activity
FT669_16895	COG0424	maF-like protein
FT669_16900	COG1399	metal-binding, possibly nucleic acid-binding protein
FT669_16905	COG0333	Belongs to the bacterial ribosomal protein bL32 family
FT669_16910	COG0416	fatty acid biosynthetic process
FT669_16915	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FT669_16925	COG1028	Short-chain dehydrogenase reductase Sdr
FT669_16930	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FT669_16950	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
FT669_16955	COG0470	DNA polymerase III
FT669_16960	COG0084	hydrolase, TatD family'
FT669_16985	COG2995	paraquat-inducible protein a
FT669_16995	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
FT669_17000	COG0372	Belongs to the citrate synthase family
FT669_17055	COG3141	response to X-ray
FT669_17070	COG1067	ATP-dependent peptidase activity
FT669_17075	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
FT669_17085	COG0488	(ABC) transporter
FT669_17095	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
FT669_17095	COG0116	Belongs to the methyltransferase superfamily
FT669_17115	COG3290	protein histidine kinase activity
FT669_17115	COG0840	transmembrane signaling receptor activity
FT669_17120	COG0835	chemotaxis
FT669_17130	COG2201	protein-glutamate methylesterase activity
FT669_17135	COG5001	Diguanylate cyclase
FT669_17135	COG4251	negative regulation of phosphorylation
FT669_17135	COG2203	Gaf domain
FT669_17135	COG3706	GGDEF domain
FT669_17160	COG0167	dihydroorotate dehydrogenase activity
FT669_17165	COG2902	Dehydrogenase
FT669_17175	COG0308	aminopeptidase N
FT669_17185	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
FT669_17190	COG1956	GAF domain-containing protein
FT669_17200	COG3278	Belongs to the heme-copper respiratory oxidase family
FT669_17215	COG2010	Cytochrome c
FT669_17240	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FT669_17245	COG0589	response to stress
FT669_17295	COG0625	glutathione transferase activity
FT669_17300	COG1869	D-ribose catabolic process
FT669_17320	COG1172	Belongs to the binding-protein-dependent transport system permease family
FT669_17325	COG1879	ABC-type sugar transport system periplasmic component
FT669_17330	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FT669_17335	COG1609	Transcriptional regulator
FT669_17360	COG0776	regulation of translation
FT669_17365	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FT669_17365	COG0072	phenylalanine-tRNA ligase activity
FT669_17370	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
FT669_17380	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
FT669_17385	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
FT669_17390	COG0291	Belongs to the bacterial ribosomal protein bL35 family
FT669_17395	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
FT669_17400	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
FT669_17415	COG0366	Alpha amylase catalytic
FT669_17430	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
FT669_17440	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FT669_17445	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FT669_17450	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
FT669_17455	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
FT669_17460	COG3313	Fe-S protein
FT669_17465	COG2942	2-epimerase
FT669_17470	COG3716	PTS system mannose fructose sorbose family IID component
FT669_17475	COG3715	PTS system
FT669_17480	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
FT669_17480	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FT669_17495	COG1609	Transcriptional regulator
FT669_17500	COG2140	Oxalate decarboxylase
FT669_17510	COG1105	Belongs to the carbohydrate kinase PfkB family
FT669_17520	COG1609	Transcriptional regulator
FT669_17525	COG0814	amino acid
FT669_17550	COG3788	relative of glutathione S-transferase, MAPEG superfamily
FT669_17555	COG0513	Belongs to the DEAD box helicase family
FT669_17565	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
FT669_17570	COG2890	protein-(glutamine-N5) methyltransferase activity
FT669_17575	COG2840	Smr protein MutS2
FT669_17580	COG3706	GGDEF domain
FT669_17600	COG0740	serine-type endopeptidase activity
FT669_17610	COG2824	Alkylphosphonate utilization operon protein PhnA
FT669_17615	COG3100	YcgL domain-containing protein
FT669_17620	COG0850	regulation of cytokinetic process
FT669_17625	COG2894	cell division
FT669_17630	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
FT669_17635	COG3099	Belongs to the UPF0263 family
FT669_17640	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FT669_17675	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
FT669_17680	COG0697	spore germination
FT669_17685	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
FT669_17690	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FT669_17750	COG3829	transcription factor binding
FT669_17775	COG3067	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
FT669_17785	COG0586	Pfam SNARE associated Golgi protein
FT669_17795	COG0556	nucleotide-excision repair
FT669_17805	COG2985	domain, Protein
FT669_17805	COG0569	domain protein
FT669_17810	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FT669_17815	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
FT669_17815	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FT669_17830	COG3069	C4-dicarboxylate transmembrane transporter activity
FT669_17845	COG3385	transposase activity
FT669_17895	COG1560	Kdo2-lipid A biosynthetic process
FT669_17910	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
FT669_17925	COG3385	transposase activity
FT669_17930	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
FT669_17940	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
FT669_17945	COG2832	Protein of unknown function (DUF454)
FT669_17950	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
FT669_17955	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
FT669_18035	COG0758	DNA mediated transformation
FT669_18050	COG1011	Hydrolase
FT669_18115	COG3593	DNA synthesis involved in DNA repair
FT669_18140	COG3148	PFAM DTW domain containing protein
FT669_18145	COG1846	Transcriptional regulator
FT669_18145	COG1940	carbohydrate kinase activity
FT669_18150	COG0840	transmembrane signaling receptor activity
FT669_18165	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
FT669_18170	COG3075	Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses fumarate or nitrate as electron acceptor
FT669_18175	COG0247	lactate metabolic process
FT669_18185	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
FT669_18190	COG0437	4 iron, 4 sulfur cluster binding
FT669_18215	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FT669_18235	COG1840	ABC-type Fe3 transport system, periplasmic component
FT669_18245	COG3842	ATPase activity
FT669_18255	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FT669_18295	COG0045	succinate-CoA ligase (ADP-forming) activity
FT669_18300	COG0508	dehydrogenase complex catalyzes the overall conversion of
FT669_18305	COG0567	Dehydrogenase, E1 component
FT669_18315	COG1053	succinate dehydrogenase
FT669_18320	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
FT669_18325	COG2009	succinate dehydrogenase
FT669_18380	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
FT669_18395	COG2501	S4 domain
FT669_18410	COG1132	(ABC) transporter
FT669_18415	COG2205	protein histidine kinase activity
FT669_18415	COG3437	response regulator, receiver
FT669_18415	COG3850	Histidine kinase
FT669_18415	COG4999	Histidine kinase
FT669_18420	COG3118	belongs to the thioredoxin family
FT669_18425	COG0471	metal ion transport
FT669_18445	COG2983	Belongs to the UPF0260 family
FT669_18455	COG1882	Formate acetyltransferase
FT669_18460	COG2116	formate transmembrane transporter activity
FT669_18465	COG1944	ATP diphosphatase activity
FT669_18475	COG0583	DNA-binding transcription factor activity
FT669_18495	COG0583	DNA-binding transcription factor activity
FT669_18505	COG2910	NAD(P)H-binding
FT669_18520	COG1022	Amp-dependent synthetase and ligase
FT669_18540	COG2885	chlorophyll binding
FT669_18565	COG2154	pterin-4-alpha-carbinolamine dehydratase
FT669_18575	COG3768	UPF0283 membrane protein
FT669_18595	COG1842	Phage shock protein A
FT669_18625	COG4172	Belongs to the ABC transporter superfamily
FT669_18630	COG0326	Molecular chaperone. Has ATPase activity
FT669_18635	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
FT669_18660	COG4104	PAAR repeat-containing protein
FT669_18710	COG0672	)-iron permease
FT669_18730	COG2814	Major facilitator Superfamily
FT669_18765	COG0596	Alpha beta hydrolase
FT669_18875	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FT669_18885	COG0527	aspartate kinase activity
FT669_18935	COG0393	Putative heavy-metal-binding
FT669_18940	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
FT669_18945	COG0285	dihydrofolate synthase activity
FT669_18950	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
FT669_18955	COG0101	tRNA pseudouridine synthase activity
FT669_18965	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
FT669_18970	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FT669_18975	COG0671	phosphoesterase, PA-phosphatase related
FT669_18980	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
FT669_18985	COG2056	Na+-H+ antiporter family
FT669_18990	COG3385	transposase activity
FT669_19000	COG2050	protein possibly involved in aromatic compounds catabolism
FT669_19010	COG0277	FAD linked oxidase domain protein
FT669_19010	COG0247	lactate metabolic process
FT669_19020	COG1253	flavin adenine dinucleotide binding
FT669_19025	COG3385	transposase activity
FT669_19045	COG0647	UMP catabolic process
FT669_19050	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
FT669_19050	COG4651	solute:proton antiporter activity
FT669_19060	COG0367	asparagine synthase
FT669_19065	COG0625	glutathione transferase activity
FT669_19075	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
FT669_19090	COG0564	pseudouridine synthase activity
FT669_19095	COG4160	amino acid transport
FT669_19115	COG2431	L-lysine efflux transmembrane transporter activity
FT669_19120	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
FT669_19125	COG3124	Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP
FT669_19135	COG1393	Belongs to the ArsC family
FT669_19140	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FT669_19145	COG4783	chaperone-mediated protein folding
FT669_19150	COG0425	Belongs to the sulfur carrier protein TusA family
FT669_19175	COG3842	ATPase activity
FT669_19180	COG3833	ABC-type maltose transport systems, permease component
FT669_19185	COG1175	transmembrane transport
FT669_19195	COG3081	Nucleoid-associated protein
FT669_19200	COG3082	Protein of unknown function (DUF1414)
FT669_19205	COG3083	sulfuric ester hydrolase activity
FT669_19210	COG1464	Belongs to the NlpA lipoprotein family
FT669_19255	COG0840	transmembrane signaling receptor activity
FT669_19265	COG0509	glycine decarboxylation via glycine cleavage system
FT669_19275	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FT669_19280	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FT669_19300	COG0243	molybdopterin cofactor binding
FT669_19305	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
FT669_19310	COG0583	DNA-binding transcription factor activity
FT669_19315	COG2814	Major facilitator Superfamily
FT669_19320	COG0625	glutathione transferase activity
FT669_19330	COG0483	inositol monophosphate 1-phosphatase activity
FT669_19345	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
FT669_19355	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FT669_19360	COG1086	Polysaccharide biosynthesis protein
FT669_19365	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
FT669_19375	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
FT669_19380	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
FT669_19390	COG2089	acid synthase
FT669_19450	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FT669_19450	COG0301	tRNA thio-modification
FT669_19470	COG2373	Large extracellular alpha-helical protein
FT669_19480	COG0446	pyridine nucleotide-disulphide oxidoreductase
FT669_19485	COG3300	MHYT domain
FT669_19485	COG5001	Diguanylate cyclase
FT669_19490	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
FT669_19500	COG3385	transposase activity
FT669_19505	COG1252	NADH dehydrogenase
FT669_19510	COG3150	esterase
FT669_19525	COG2354	Protein conserved in bacteria
FT669_19535	COG1301	dicarboxylic acid transport
FT669_19550	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
FT669_19565	COG0537	adenosine 5'-monophosphoramidase activity
FT669_19600	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FT669_19605	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FT669_19615	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
FT669_19620	COG0287	Prephenate dehydrogenase
FT669_19620	COG1605	Chorismate mutase
FT669_19630	COG1199	ATP-dependent helicase activity
FT669_19640	COG0123	including yeast histone deacetylase and acetoin utilization protein
FT669_19645	COG0477	Major facilitator Superfamily
FT669_19650	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
FT669_19675	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
FT669_19680	COG2197	response regulator
FT669_19700	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FT669_19705	COG0765	amino acid transport
FT669_19745	COG1253	flavin adenine dinucleotide binding
FT669_19750	COG0704	Plays a role in the regulation of phosphate uptake
FT669_19755	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
FT669_19760	COG0581	inorganic phosphate transmembrane transporter activity
FT669_19770	COG0590	tRNA wobble adenosine to inosine editing
FT669_19785	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
FT669_19805	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
FT669_19810	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
FT669_19815	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
FT669_19820	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
FT669_19845	COG2716	regulation of RNA biosynthetic process
FT669_19850	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
FT669_19860	COG2239	Acts as a magnesium transporter
FT669_19875	COG1705	Flagellar rod assembly protein muramidase FlgJ
FT669_19875	COG3951	Flagellar rod assembly protein muramidase FlgJ
FT669_19880	COG1706	bacterial-type flagellum-dependent cell motility
FT669_19885	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
FT669_19905	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
FT669_19915	COG1815	bacterial-type flagellum-dependent cell motility
FT669_19920	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
FT669_19925	COG0835	chemotaxis
FT669_19925	COG0784	Response regulator, receiver
FT669_19930	COG1261	Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly
FT669_19945	COG0622	Phosphoesterase
FT669_19950	COG4166	transmembrane transport
FT669_19990	COG1349	DNA-binding transcription factor activity
FT669_19995	COG0697	spore germination
FT669_20025	COG1278	Cold shock
FT669_20050	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
FT669_20050	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FT669_20060	COG3433	isochorismatase activity
FT669_20060	COG1535	isochorismatase
FT669_20065	COG1021	2,3-dihydroxybenzoate-AMP ligase
FT669_20070	COG1169	isochorismate synthase
FT669_20075	COG4771	TonB-dependent receptor
FT669_20080	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
FT669_20090	COG0741	lytic transglycosylase activity
FT669_20100	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
FT669_20125	COG0729	surface antigen
FT669_20135	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FT669_20145	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
FT669_20165	COG4136	ATPase activity
FT669_20175	COG2951	lytic endotransglycosylase activity
FT669_20180	COG0033	Phosphoglucomutase
FT669_20185	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
FT669_20205	COG0716	FMN binding
FT669_20215	COG0735	belongs to the Fur family
FT669_20220	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FT669_20230	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FT669_20230	COG2190	(PTS) system
FT669_20230	COG1263	PTS System
FT669_20235	COG0363	glucosamine-6-phosphate deaminase activity
FT669_20240	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
FT669_20245	COG1940	carbohydrate kinase activity
FT669_20245	COG1846	Transcriptional regulator
FT669_20255	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
FT669_20255	COG2199	diguanylate cyclase activity
FT669_20265	COG3279	Response regulator of the LytR AlgR family
FT669_20270	COG1966	Carbon starvation protein
FT669_20285	COG1061	Type III restriction enzyme res subunit
FT669_20290	COG2027	D-alanyl-D-alanine carboxypeptidase
FT669_20295	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
FT669_20300	COG3021	interspecies interaction between organisms
FT669_20315	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FT669_20340	COG0501	Belongs to the peptidase M48B family
FT669_20345	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
FT669_20350	COG2226	methyltransferase
FT669_20350	COG1073	alpha beta
FT669_20355	COG0156	8-amino-7-oxononanoate synthase activity
FT669_20360	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
FT669_20380	COG0017	Asparaginyl-tRNA synthetase
FT669_20390	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
FT669_20405	COG3069	C4-dicarboxylate transmembrane transporter activity
FT669_20415	COG1393	Belongs to the ArsC family
FT669_20425	COG1876	peptidase activity
FT669_20435	COG3263	regulation of cellular component size
FT669_20450	COG1280	lysine exporter protein (LysE YggA)
FT669_20480	COG1957	nucleoside hydrolase
FT669_20485	COG0564	pseudouridine synthase activity
FT669_20495	COG1454	alcohol dehydrogenase
FT669_20500	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FT669_20515	COG0095	Lipoate-protein ligase
FT669_20520	COG5001	Diguanylate cyclase
FT669_20535	COG2391	methyltransferase activity
FT669_20565	COG0484	heat shock protein binding
FT669_20570	COG0443	Heat shock 70 kDa protein
FT669_20575	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
FT669_20580	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
FT669_20595	COG1227	inorganic diphosphatase activity
FT669_20600	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FT669_20625	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
FT669_20640	COG1091	dTDP-4-dehydrorhamnose reductase activity
FT669_20655	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
FT669_20670	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
FT669_20690	COG1086	Polysaccharide biosynthesis protein
FT669_20725	COG1309	transcriptional regulator
FT669_20750	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
FT669_20775	COG0813	purine-nucleoside phosphorylase activity
FT669_20810	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
FT669_20815	COG0083	homoserine kinase activity
FT669_20830	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
FT669_20840	COG1946	Acyl-CoA thioesterase
FT669_20860	COG1993	acr, cog1993
FT669_20870	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
FT669_20880	COG0009	L-threonylcarbamoyladenylate synthase
FT669_20890	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
FT669_20895	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
FT669_20895	COG0512	Glutamine amidotransferase of anthranilate synthase
FT669_20900	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
FT669_20910	COG0133	tryptophan synthase activity
FT669_20915	COG0159	tryptophan synthase activity
FT669_20930	COG1988	membrane-bound metal-dependent
FT669_20945	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
FT669_20960	COG0798	PFAM Bile acid sodium symporter
FT669_21000	COG0745	RESPONSE REGULATOR receiver
FT669_21020	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
FT669_21040	COG1720	tRNA m6t6A37 methyltransferase activity
FT669_21060	COG3161	chorismate lyase activity
FT669_21065	COG3152	Membrane
FT669_21095	COG1917	Cupin 2, conserved barrel domain protein
FT669_21095	COG1396	sequence-specific DNA binding
FT669_21110	COG0531	amino acid
FT669_21115	COG0531	amino acid
FT669_21125	COG1283	sodium-dependent phosphate transmembrane transporter activity
FT669_21135	COG2974	May be involved in recombination
FT669_21145	COG0420	3'-5' exonuclease activity
FT669_21150	COG0419	ATPase involved in DNA repair
FT669_21155	COG3384	dioxygenase
FT669_21165	COG0469	pyruvate kinase activity
FT669_21170	COG1196	nuclear chromosome segregation
FT669_21170	COG3264	Mechanosensitive ion channel
FT669_21180	COG3706	GGDEF domain
FT669_21185	COG2190	(PTS) system
FT669_21195	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
FT669_21200	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
FT669_21205	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FT669_21225	COG3267	Type II secretory pathway component ExeA
FT669_21225	COG3409	Peptidoglycan-binding domain 1 protein
FT669_21245	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
FT669_21250	COG1459	type II secretion system
FT669_21255	COG2165	general secretion pathway protein
FT669_21265	COG2165	general secretion pathway protein
FT669_21270	COG4795	General secretion pathway protein
FT669_21275	COG3156	type II secretion system protein K
FT669_21285	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
FT669_21300	COG0670	Belongs to the BI1 family
FT669_21305	COG1289	transmembrane transporter activity
FT669_21310	COG2920	part of a sulfur-relay system
FT669_21315	COG0673	inositol 2-dehydrogenase activity
FT669_21325	COG0583	DNA-binding transcription factor activity
FT669_21365	COG1032	radical SAM domain protein
FT669_21375	COG1566	PFAM secretion protein HlyD family protein
FT669_21385	COG1752	Esterase of the alpha-beta hydrolase superfamily
FT669_21390	COG0733	neurotransmitter:sodium symporter activity
FT669_21410	COG2885	chlorophyll binding
FT669_21410	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
FT669_21420	COG0281	malic enzyme
FT669_21430	COG0534	Mate efflux family protein
FT669_21445	COG2233	PERMEase
FT669_21455	COG0019	diaminopimelate decarboxylase activity
FT669_21475	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
FT669_21490	COG0545	Peptidyl-prolyl cis-trans isomerase
FT669_21495	COG3142	Participates in the control of copper homeostasis