locus-tag	class	description
HQ399_00005	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
HQ399_00010	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
HQ399_00015	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
HQ399_00020	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
HQ399_00025	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
HQ399_00030	COG0255	Belongs to the universal ribosomal protein uL29 family
HQ399_00035	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
HQ399_00040	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
HQ399_00045	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
HQ399_00050	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
HQ399_00055	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
HQ399_00060	COG0089	rRNA binding
HQ399_00065	COG0088	Forms part of the polypeptide exit tunnel
HQ399_00070	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
HQ399_00075	COG0051	transcription antitermination factor activity, RNA binding
HQ399_00095	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
HQ399_00100	COG2183	response to ionizing radiation
HQ399_00120	COG0596	Alpha beta hydrolase
HQ399_00125	COG1040	competence protein
HQ399_00130	COG0316	Belongs to the HesB IscA family
HQ399_00130	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
HQ399_00135	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
HQ399_00140	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
HQ399_00145	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HQ399_00150	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
HQ399_00155	COG4942	peptidase
HQ399_00165	COG1609	Transcriptional regulator
HQ399_00180	COG0800	Aldolase
HQ399_00190	COG3265	gluconokinase activity
HQ399_00195	COG2610	gluconate transmembrane transporter activity
HQ399_00200	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HQ399_00205	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
HQ399_00215	COG0456	acetyltransferase
HQ399_00220	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
HQ399_00225	COG1490	D-aminoacyl-tRNA deacylase activity
HQ399_00230	COG1295	ribonuclease BN
HQ399_00235	COG0281	malic enzyme
HQ399_00240	COG0814	amino acid
HQ399_00245	COG0702	epimerase
HQ399_00255	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
HQ399_00260	COG0254	rRNA binding
HQ399_00275	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
HQ399_00280	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
HQ399_00290	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
HQ399_00300	COG0514	ATP-dependent DNA helicase (RecQ)
HQ399_00305	COG2050	protein possibly involved in aromatic compounds catabolism
HQ399_00320	COG2258	MOSC domain
HQ399_00325	COG1177	transmembrane transport
HQ399_00330	COG1176	ABC-type spermidine putrescine transport system, permease component I
HQ399_00335	COG3842	ATPase activity
HQ399_00355	COG0174	glutamine synthetase
HQ399_00375	COG3045	CreA protein
HQ399_00380	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HQ399_00385	COG0443	Heat shock 70 kDa protein
HQ399_00400	COG0366	Alpha amylase catalytic
HQ399_00415	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HQ399_00440	COG3250	beta-galactosidase activity
HQ399_00445	COG1609	Transcriptional regulator
HQ399_00450	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
HQ399_00455	COG1085	galactose-1-phosphate uridylyltransferase
HQ399_00460	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
HQ399_00465	COG2017	converts alpha-aldose to the beta-anomer
HQ399_00470	COG1968	undecaprenyl-diphosphatase activity
HQ399_00480	COG1595	DNA-templated transcription, initiation
HQ399_00500	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
HQ399_00505	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
HQ399_00515	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HQ399_00520	COG1131	(ABC) transporter
HQ399_00525	COG0842	Transport permease protein
HQ399_00530	COG0842	Transport permease protein
HQ399_00535	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
HQ399_00545	COG2116	formate transmembrane transporter activity
HQ399_00550	COG1648	precorrin-2 dehydrogenase activity
HQ399_00550	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
HQ399_00555	COG3177	Filamentation induced by cAMP protein fic
HQ399_00565	COG2239	Acts as a magnesium transporter
HQ399_00570	COG1079	Belongs to the binding-protein-dependent transport system permease family
HQ399_00575	COG4603	Belongs to the binding-protein-dependent transport system permease family
HQ399_00580	COG3845	ABC transporter
HQ399_00585	COG1744	ABC transporter substrate-binding protein PnrA-like
HQ399_00590	COG0210	DNA helicase
HQ399_00600	COG1943	Transposase
HQ399_00645	COG1280	lysine exporter protein (LysE YggA)
HQ399_00680	COG3306	glycosyltransferase involved in LPS biosynthesis
HQ399_00685	COG0438	transferase activity, transferring glycosyl groups
HQ399_00705	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
HQ399_00715	COG0156	8-amino-7-oxononanoate synthase activity
HQ399_00720	COG1063	alcohol dehydrogenase
HQ399_00725	COG3245	cytochrome
HQ399_00735	COG0210	DNA helicase
HQ399_00740	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
HQ399_00745	COG2166	iron-sulfur cluster assembly
HQ399_00750	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
HQ399_00780	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
HQ399_00785	COG4206	TonB-dependent receptor
HQ399_00790	COG0583	DNA-binding transcription factor activity
HQ399_00805	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
HQ399_00810	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
HQ399_00815	COG2223	nitrite transmembrane transporter activity
HQ399_00820	COG3279	Response regulator of the LytR AlgR family
HQ399_00825	COG3275	phosphorelay sensor kinase activity
HQ399_00830	COG2081	HI0933 family
HQ399_00835	COG1528	Iron-storage protein
HQ399_00840	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
HQ399_00845	COG0589	response to stress
HQ399_00885	COG3642	lipopolysaccharide core region biosynthetic process
HQ399_00890	COG0859	PFAM glycosyl transferase family 9
HQ399_00900	COG1758	RNA polymerase activity
HQ399_00905	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HQ399_00910	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HQ399_00920	COG2267	carboxylic ester hydrolase activity
HQ399_00925	COG0561	phosphatase activity
HQ399_00960	COG1309	transcriptional regulator
HQ399_00965	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HQ399_00970	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HQ399_00975	COG4191	Histidine kinase
HQ399_00975	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HQ399_00980	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
HQ399_01000	COG2205	protein histidine kinase activity
HQ399_01005	COG0745	RESPONSE REGULATOR receiver
HQ399_01010	COG2814	Major facilitator Superfamily
HQ399_01025	COG3977	Valine--pyruvate aminotransferase
HQ399_01030	COG0071	Belongs to the small heat shock protein (HSP20) family
HQ399_01035	COG0071	Belongs to the small heat shock protein (HSP20) family
HQ399_01050	COG2378	regulation of single-species biofilm formation
HQ399_01075	COG0592	DNA-directed DNA polymerase activity
HQ399_01080	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
HQ399_01095	COG1126	abc transporter atp-binding protein
HQ399_01100	COG0230	Belongs to the bacterial ribosomal protein bL34 family
HQ399_01105	COG0594	ribonuclease P activity
HQ399_01110	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
HQ399_01115	COG0706	membrane insertase activity
HQ399_01120	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
HQ399_01130	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
HQ399_01135	COG1120	ATPase activity
HQ399_01140	COG4615	Cyclic peptide transporter
HQ399_01150	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
HQ399_01155	COG0445	tRNA wobble uridine modification
HQ399_01160	COG0357	Ribosomal RNA small subunit methyltransferase G
HQ399_01165	COG1192	Involved in chromosome partitioning
HQ399_01170	COG1475	DNA binding
HQ399_01180	COG0356	it plays a direct role in the translocation of protons across the membrane
HQ399_01190	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
HQ399_01195	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HQ399_01200	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
HQ399_01205	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
HQ399_01210	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
HQ399_01215	COG0355	proton-transporting ATP synthase activity, rotational mechanism
HQ399_01220	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
HQ399_01225	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
HQ399_01270	COG0297	glycogen (starch) synthase activity
HQ399_01270	COG0438	transferase activity, transferring glycosyl groups
HQ399_01285	COG4452	Inner membrane protein CreD
HQ399_01300	COG2205	protein histidine kinase activity
HQ399_01305	COG0745	RESPONSE REGULATOR receiver
HQ399_01310	COG1349	DNA-binding transcription factor activity
HQ399_01315	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
HQ399_01320	COG2771	luxR family
HQ399_01330	COG0811	peptide transport
HQ399_01335	COG0811	peptide transport
HQ399_01340	COG0848	biopolymer transport protein
HQ399_01345	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
HQ399_01380	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
HQ399_01385	COG0402	S-adenosylhomocysteine deaminase activity
HQ399_01395	COG2226	methyltransferase
HQ399_01405	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
HQ399_01415	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
HQ399_01420	COG0805	protein transport
HQ399_01425	COG0084	hydrolase, TatD family'
HQ399_01435	COG3469	chitinase activity
HQ399_01450	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HQ399_01455	COG0742	ribosomal rna small subunit methyltransferase
HQ399_01465	COG0248	Ppx GppA phosphatase
HQ399_01470	COG0513	Belongs to the DEAD box helicase family
HQ399_01475	COG3118	belongs to the thioredoxin family
HQ399_01490	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
HQ399_01500	COG5001	Diguanylate cyclase
HQ399_01500	COG5002	protein histidine kinase activity
HQ399_01505	COG2960	long-chain fatty acid transporting porin activity
HQ399_01515	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HQ399_01550	COG0840	transmembrane signaling receptor activity
HQ399_01565	COG5001	Diguanylate cyclase
HQ399_01565	COG3706	GGDEF domain
HQ399_01565	COG4251	negative regulation of phosphorylation
HQ399_01565	COG2203	Gaf domain
HQ399_01575	COG0751	glycine-tRNA ligase activity
HQ399_01580	COG0752	glycyl-tRNA synthetase alpha subunit
HQ399_01585	COG2818	Glycosylase
HQ399_01590	COG0840	transmembrane signaling receptor activity
HQ399_01595	COG2885	chlorophyll binding
HQ399_01600	COG0251	oxidation-reduction process
HQ399_01605	COG0425	Belongs to the sulfur carrier protein TusA family
HQ399_01630	COG0183	Belongs to the thiolase family
HQ399_01635	COG1024	Enoyl-CoA hydratase
HQ399_01635	COG1250	3-hydroxyacyl-CoA dehydrogenase
HQ399_01640	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
HQ399_01645	COG0006	proline dipeptidase activity
HQ399_01650	COG1739	Uncharacterized protein family UPF0029
HQ399_01655	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
HQ399_01660	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
HQ399_01715	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
HQ399_01720	COG0166	Belongs to the GPI family
HQ399_01725	COG0668	transmembrane transport
HQ399_01730	COG1309	transcriptional regulator
HQ399_01735	COG0756	dUTP diphosphatase activity
HQ399_01740	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
HQ399_01745	COG2003	Belongs to the UPF0758 family
HQ399_01750	COG0227	Belongs to the bacterial ribosomal protein bL28 family
HQ399_01755	COG0267	Belongs to the bacterial ribosomal protein bL33 family
HQ399_01765	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
HQ399_01770	COG2990	Protein conserved in bacteria
HQ399_01775	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
HQ399_01780	COG0859	PFAM glycosyl transferase family 9
HQ399_01785	COG0463	Glycosyl transferase, family 2
HQ399_01790	COG0859	PFAM glycosyl transferase family 9
HQ399_01795	COG1519	Transferase
HQ399_01810	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
HQ399_01815	COG1609	Transcriptional regulator
HQ399_01820	COG0604	alcohol dehydrogenase
HQ399_01840	COG3161	chorismate lyase activity
HQ399_01845	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
HQ399_01850	COG2937	Belongs to the GPAT DAPAT family
HQ399_01855	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
HQ399_01870	COG0534	Mate efflux family protein
HQ399_01875	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
HQ399_01880	COG2205	protein histidine kinase activity
HQ399_01885	COG0745	RESPONSE REGULATOR receiver
HQ399_01905	COG3074	FtsZ-dependent cytokinesis
HQ399_01910	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
HQ399_01915	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HQ399_01915	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HQ399_01920	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
HQ399_01955	COG1609	Transcriptional regulator
HQ399_01960	COG3250	beta-galactosidase activity
HQ399_01965	COG2731	YhcH YjgK YiaL family protein
HQ399_01970	COG0531	amino acid
HQ399_01975	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HQ399_01980	COG0531	amino acid
HQ399_01985	COG0385	Bile acid
HQ399_01990	COG1262	PFAM Formylglycine-generating sulfatase enzyme
HQ399_02030	COG0583	DNA-binding transcription factor activity
HQ399_02040	COG3188	usher protein
HQ399_02045	COG3121	Chaperone
HQ399_02050	COG3539	Fimbrial protein
HQ399_02065	COG1566	PFAM secretion protein HlyD family protein
HQ399_02075	COG1561	YicC-like family, N-terminal region
HQ399_02080	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
HQ399_02085	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
HQ399_02100	COG5001	Diguanylate cyclase
HQ399_02100	COG2203	Gaf domain
HQ399_02100	COG3706	GGDEF domain
HQ399_02100	COG4251	negative regulation of phosphorylation
HQ399_02105	COG3084	Protein conserved in bacteria
HQ399_02115	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
HQ399_02120	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
HQ399_02130	COG1335	isochorismatase
HQ399_02140	COG1683	Conserved Protein
HQ399_02145	COG0204	Acyl-transferase
HQ399_02150	COG0204	Acyl-transferase
HQ399_02155	COG0606	chelatase, subunit chli
HQ399_02165	COG3978	acetolactate synthase activity
HQ399_02175	COG0129	dihydroxy-acid dehydratase activity
HQ399_02185	COG2885	chlorophyll binding
HQ399_02185	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
HQ399_02200	COG2391	methyltransferase activity
HQ399_02205	COG0840	transmembrane signaling receptor activity
HQ399_02210	COG2962	Rard protein
HQ399_02220	COG1012	belongs to the aldehyde dehydrogenase family
HQ399_02225	COG1396	sequence-specific DNA binding
HQ399_02230	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
HQ399_02240	COG0519	Catalyzes the synthesis of GMP from XMP
HQ399_02240	COG0518	GMP synthase (glutamine-hydrolyzing) activity
HQ399_02245	COG0583	DNA-binding transcription factor activity
HQ399_02250	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HQ399_02270	COG1322	Protein conserved in bacteria
HQ399_02275	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
HQ399_02280	COG2204	response regulator
HQ399_02295	COG0174	glutamine synthetase
HQ399_02300	COG1217	gtp-binding protein TYPA
HQ399_02305	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
HQ399_02310	COG0569	domain protein
HQ399_02315	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
HQ399_02315	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
HQ399_02320	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
HQ399_02325	COG0242	peptide deformylase activity
HQ399_02330	COG1652	LysM domain
HQ399_02335	COG0758	DNA mediated transformation
HQ399_02340	COG2922	Belongs to the Smg family
HQ399_02345	COG0551	DNA topoisomerase type I activity
HQ399_02355	COG0009	L-threonylcarbamoyladenylate synthase
HQ399_02360	COG0408	coproporphyrinogen oxidase activity
HQ399_02365	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
HQ399_02375	COG0218	Necessary for normal cell division and for the maintenance of normal septation
HQ399_02385	COG3078	GTPase activator activity
HQ399_02395	COG0635	Involved in the biosynthesis of porphyrin-containing compound
HQ399_02425	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
HQ399_02430	COG1288	antiporter activity
HQ399_02435	COG1438	arginine binding
HQ399_02440	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
HQ399_02445	COG0540	Belongs to the ATCase OTCase family
HQ399_02460	COG0688	phosphatidylethanolamine metabolic process
HQ399_02465	COG0583	DNA-binding transcription factor activity
HQ399_02485	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
HQ399_02500	COG3040	lipid binding
HQ399_02505	COG2207	Transcriptional regulator
HQ399_02510	COG1979	alcohol dehydrogenase
HQ399_02515	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
HQ399_02520	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
HQ399_02590	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
HQ399_02640	COG4695	Portal protein
HQ399_02660	COG2176	DNA-directed DNA polymerase activity
HQ399_02660	COG5002	protein histidine kinase activity
HQ399_02735	COG4974	Belongs to the 'phage' integrase family
HQ399_02745	COG3681	Belongs to the UPF0597 family
HQ399_02755	COG0446	pyridine nucleotide-disulphide oxidoreductase
HQ399_02760	COG2076	Multidrug Resistance protein
HQ399_02765	COG2076	Multidrug Resistance protein
HQ399_02770	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
HQ399_02775	COG0726	polysaccharide deacetylase
HQ399_02780	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
HQ399_02780	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
HQ399_02785	COG0463	Glycosyl transferase, family 2
HQ399_02790	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
HQ399_02805	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
HQ399_02810	COG0564	pseudouridine synthase activity
HQ399_02820	COG0542	response to heat
HQ399_02825	COG2502	aspartate--ammonia ligase
HQ399_02830	COG1522	sequence-specific DNA binding
HQ399_02840	COG5413	integral membrane protein
HQ399_02860	COG2205	protein histidine kinase activity
HQ399_02870	COG2204	response regulator
HQ399_02915	COG0243	molybdopterin cofactor binding
HQ399_02920	COG3005	denitrification pathway
HQ399_02925	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HQ399_02925	COG4191	Histidine kinase
HQ399_02935	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HQ399_02940	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
HQ399_02945	COG0569	domain protein
HQ399_02950	COG0812	UDP-N-acetylmuramate dehydrogenase activity
HQ399_02975	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
HQ399_02990	COG0250	Participates in transcription elongation, termination and antitermination
HQ399_02995	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
HQ399_03000	COG0081	regulation of translation
HQ399_03005	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
HQ399_03010	COG0222	ribosome binding
HQ399_03015	COG0085	RNA polymerase activity
HQ399_03020	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HQ399_03025	COG2964	Protein conserved in bacteria
HQ399_03035	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
HQ399_03040	COG2923	Belongs to the DsrF TusC family
HQ399_03045	COG2168	tRNA wobble position uridine thiolation
HQ399_03050	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
HQ399_03055	COG0049	tRNA binding
HQ399_03060	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
HQ399_03065	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
HQ399_03070	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
HQ399_03125	COG3714	YhhN family
HQ399_03140	COG0583	DNA-binding transcription factor activity
HQ399_03150	COG1301	dicarboxylic acid transport
HQ399_03160	COG2095	MarC family integral membrane protein
HQ399_03170	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
HQ399_03180	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
HQ399_03190	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HQ399_03205	COG1770	oligopeptidase
HQ399_03220	COG4221	oxidoreductase activity
HQ399_03225	COG0583	DNA-binding transcription factor activity
HQ399_03230	COG2249	NAD(P)H dehydrogenase (quinone) activity
HQ399_03255	COG0742	ribosomal rna small subunit methyltransferase
HQ399_03260	COG0552	protein localization to endoplasmic reticulum
HQ399_03270	COG2177	Part of the ABC transporter FtsEX involved in
HQ399_03280	COG0288	reversible hydration of carbon dioxide
HQ399_03285	COG2188	Transcriptional regulator
HQ399_03290	COG1228	amidohydrolase
HQ399_03295	COG0010	Belongs to the arginase family
HQ399_03300	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
HQ399_03305	COG2986	histidine ammonia-lyase
HQ399_03310	COG0387	Pfam Sodium calcium exchanger
HQ399_03320	COG2200	EAL domain
HQ399_03325	COG2200	EAL domain
HQ399_03325	COG2199	diguanylate cyclase activity
HQ399_03355	COG1450	Type ii and iii secretion system protein
HQ399_03370	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
HQ399_03375	COG1459	type II secretion system
HQ399_03390	COG2165	general secretion pathway protein
HQ399_03395	COG4968	Prepilin-type N-terminal cleavage methylation domain
HQ399_03420	COG1077	Cell shape determining protein MreB Mrl
HQ399_03425	COG1792	Involved in formation and maintenance of cell shape
HQ399_03430	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
HQ399_03435	COG0424	maF-like protein
HQ399_03440	COG1530	ribonuclease E activity
HQ399_03445	COG3164	Protein of unknown function
HQ399_03460	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
HQ399_03465	COG0312	modulator of DNA gyrase
HQ399_03480	COG0477	Major facilitator Superfamily
HQ399_03520	COG0646	methionine synthase
HQ399_03520	COG1410	methionine synthase
HQ399_03525	COG0189	ligase activity
HQ399_03530	COG0642	Histidine kinase
HQ399_03535	COG0745	RESPONSE REGULATOR receiver
HQ399_03555	COG0789	Transcriptional regulator
HQ399_03560	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
HQ399_03565	COG0352	thiamine-phosphate diphosphorylase activity
HQ399_03570	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
HQ399_03580	COG2022	thiamine diphosphate biosynthetic process
HQ399_03585	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
HQ399_03595	COG3417	Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1B (PBP1b)
HQ399_03600	COG0110	maltose O-acetyltransferase activity
HQ399_03615	COG0814	amino acid
HQ399_03620	COG3932	Exopolysaccharide synthesis, ExoD
HQ399_03635	COG0004	ammonium transporteR
HQ399_03640	COG3133	Outer membrane lipoprotein
HQ399_03645	COG0456	acetyltransferase
HQ399_03670	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
HQ399_03675	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
HQ399_03690	COG0494	nUDIX hydrolase
HQ399_03695	COG0628	permease
HQ399_03705	COG2957	Belongs to the agmatine deiminase family
HQ399_03725	COG0583	DNA-binding transcription factor activity
HQ399_03730	COG3284	Transcriptional regulator
HQ399_03740	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HQ399_03740	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
HQ399_03740	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
HQ399_03745	COG1461	Dihydroxyacetone kinase
HQ399_03750	COG2376	Dihydroxyacetone kinase
HQ399_03755	COG2252	PERMEase
HQ399_03775	COG0629	single-stranded DNA binding
HQ399_03780	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
HQ399_03790	COG3047	cAMP biosynthetic process
HQ399_03795	COG0840	transmembrane signaling receptor activity
HQ399_03820	COG3135	benzoate transporter
HQ399_03825	COG1396	sequence-specific DNA binding
HQ399_03885	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
HQ399_03890	COG0038	chloride channel
HQ399_03900	COG0316	Belongs to the HesB IscA family
HQ399_03905	COG1757	Na H antiporter
HQ399_03945	COG0297	glycogen (starch) synthase activity
HQ399_03950	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
HQ399_03955	COG2813	Specifically methylates the guanine in position
HQ399_03960	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HQ399_03965	COG3025	triphosphatase activity
HQ399_03970	COG1392	Phosphate transport regulator
HQ399_03975	COG0306	phosphate transporter
HQ399_03980	COG0527	aspartate kinase activity
HQ399_03980	COG0460	homoserine dehydrogenase
HQ399_03985	COG0626	cystathionine gamma-synthase activity
HQ399_04000	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HQ399_04005	COG0814	amino acid
HQ399_04010	COG1218	3'(2'),5'-bisphosphate nucleotidase
HQ399_04015	COG0494	nUDIX hydrolase
HQ399_04020	COG1011	Hydrolase
HQ399_04035	COG0110	maltose O-acetyltransferase activity
HQ399_04040	COG3174	membrane
HQ399_04045	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
HQ399_04055	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
HQ399_04060	COG4208	sulfate ABC transporter
HQ399_04065	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
HQ399_04070	COG0583	DNA-binding transcription factor activity
HQ399_04075	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
HQ399_04080	COG0765	amino acid transport
HQ399_04090	COG1126	abc transporter atp-binding protein
HQ399_04095	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HQ399_04100	COG3397	chitin binding
HQ399_04105	COG0840	transmembrane signaling receptor activity
HQ399_04120	COG0726	polysaccharide deacetylase
HQ399_04120	COG1649	PFAM Uncharacterised BCR, COG1649
HQ399_04125	COG1215	transferase activity, transferring glycosyl groups
HQ399_04155	COG1328	CTP reductase activity
HQ399_04160	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HQ399_04175	COG1448	Aminotransferase
HQ399_04215	COG0513	Belongs to the DEAD box helicase family
HQ399_04225	COG3568	Endonuclease Exonuclease Phosphatase
HQ399_04245	COG3112	Uncharacterised protein family (UPF0231)
HQ399_04250	COG3835	regulator
HQ399_04255	COG2610	gluconate transmembrane transporter activity
HQ399_04260	COG1929	Belongs to the glycerate kinase type-1 family
HQ399_04275	COG0583	DNA-binding transcription factor activity
HQ399_04280	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
HQ399_04290	COG1872	DUF167
HQ399_04295	COG0762	integral membrane protein
HQ399_04300	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HQ399_04305	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
HQ399_04320	COG3022	response to hydroperoxide
HQ399_04340	COG0347	Belongs to the P(II) protein family
HQ399_04345	COG1840	ABC-type Fe3 transport system, periplasmic component
HQ399_04355	COG3842	ATPase activity
HQ399_04360	COG2837	iron assimilation
HQ399_04365	COG1438	arginine binding
HQ399_04370	COG1126	abc transporter atp-binding protein
HQ399_04375	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HQ399_04380	COG4215	(ABC) transporter
HQ399_04385	COG4160	amino acid transport
HQ399_04390	COG0039	L-malate dehydrogenase activity
HQ399_04395	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
HQ399_04400	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
HQ399_04400	COG1017	nitric oxide dioxygenase activity
HQ399_04410	COG4536	flavin adenine dinucleotide binding
HQ399_04415	COG4137	Cytochrome C assembly protein
HQ399_04420	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
HQ399_04425	COG0228	four-way junction DNA binding
HQ399_04430	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
HQ399_04435	COG0336	Belongs to the RNA methyltransferase TrmD family
HQ399_04440	COG0335	large ribosomal subunit rRNA binding
HQ399_04455	COG1051	belongs to the nudix hydrolase family
HQ399_04460	COG3605	phosphoenolpyruvate-protein phosphotransferase activity
HQ399_04465	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
HQ399_04470	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
HQ399_04475	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
HQ399_04485	COG0583	DNA-binding transcription factor activity
HQ399_04490	COG0640	Transcriptional regulator
HQ399_04495	COG0268	Binds directly to 16S ribosomal RNA
HQ399_04500	COG0728	peptidoglycan biosynthetic process
HQ399_04505	COG0196	riboflavin kinase activity
HQ399_04510	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
HQ399_04515	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
HQ399_04520	COG1047	Peptidyl-prolyl cis-trans
HQ399_04525	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
HQ399_04560	COG4969	Belongs to the N-Me-Phe pilin family
HQ399_04565	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
HQ399_04565	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
HQ399_04580	COG1854	S-ribosylhomocysteine lyase activity
HQ399_04590	COG2165	general secretion pathway protein
HQ399_04595	COG0084	hydrolase, TatD family'
HQ399_04600	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
HQ399_04610	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
HQ399_04615	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
HQ399_04620	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
HQ399_04625	COG0813	purine-nucleoside phosphorylase activity
HQ399_04635	COG0560	Phosphoserine phosphatase
HQ399_04650	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
HQ399_04660	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
HQ399_04665	COG0776	regulation of translation
HQ399_04680	COG1914	H( )-stimulated, divalent metal cation uptake system
HQ399_04685	COG0360	Binds together with S18 to 16S ribosomal RNA
HQ399_04690	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
HQ399_04695	COG0359	binds to the 23S rRNA
HQ399_04700	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
HQ399_04725	COG0604	alcohol dehydrogenase
HQ399_04725	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HQ399_04725	COG3321	synthase
HQ399_04725	COG4221	oxidoreductase activity
HQ399_04730	COG1238	metal cluster binding
HQ399_04735	COG0612	Peptidase, M16
HQ399_04740	COG2918	glutathione biosynthetic process
HQ399_04745	COG1022	Amp-dependent synthetase and ligase
HQ399_04750	COG0456	acetyltransferase
HQ399_04765	COG2425	protein containing a von Willebrand factor type A (vWA) domain
HQ399_04780	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
HQ399_04790	COG0477	Major facilitator Superfamily
HQ399_04795	COG0583	DNA-binding transcription factor activity
HQ399_04805	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HQ399_04810	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HQ399_04820	COG0673	inositol 2-dehydrogenase activity
HQ399_04830	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
HQ399_04835	COG0635	Involved in the biosynthesis of porphyrin-containing compound
HQ399_04840	COG3036	rescue of stalled ribosome
HQ399_04850	COG0138	bifunctional purine biosynthesis protein purh
HQ399_04855	COG0151	Belongs to the GarS family
HQ399_04920	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
HQ399_04935	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HQ399_04945	COG1610	YqeY-like protein
HQ399_04950	COG0828	Belongs to the bacterial ribosomal protein bS21 family
HQ399_04955	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
HQ399_04960	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
HQ399_04965	COG1027	Aspartate ammonia-lyase
HQ399_04970	COG3030	protein affecting phage T7 exclusion by the F plasmid
HQ399_04975	COG0534	Mate efflux family protein
HQ399_04980	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
HQ399_04985	COG0459	protein refolding
HQ399_05035	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
HQ399_05040	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
HQ399_05045	COG1178	ABC-type Fe3 transport system permease component
HQ399_05065	COG0066	3-isopropylmalate dehydratase activity
HQ399_05070	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
HQ399_05075	COG0473	3-isopropylmalate dehydrogenase activity
HQ399_05080	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
HQ399_05105	COG0028	Belongs to the TPP enzyme family
HQ399_05110	COG0440	acetolactate synthase activity
HQ399_05145	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
HQ399_05160	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HQ399_05190	COG0745	RESPONSE REGULATOR receiver
HQ399_05195	COG3104	oligopeptide transport
HQ399_05200	COG1210	Utp--glucose-1-phosphate uridylyltransferase
HQ399_05205	COG1555	photosystem II stabilization
HQ399_05210	COG0280	phosphate acetyltransferase
HQ399_05210	COG0857	belongs to the CobB CobQ family
HQ399_05215	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HQ399_05225	COG3013	Belongs to the UPF0304 family
HQ399_05230	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
HQ399_05235	COG2716	regulation of RNA biosynthetic process
HQ399_05240	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HQ399_05245	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
HQ399_05250	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
HQ399_05285	COG0784	Response regulator, receiver
HQ399_05285	COG2198	Histidine kinase
HQ399_05285	COG5002	protein histidine kinase activity
HQ399_05310	COG0840	transmembrane signaling receptor activity
HQ399_05320	COG1464	Belongs to the NlpA lipoprotein family
HQ399_05325	COG2011	ABC-type metal ion transport system permease component
HQ399_05330	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
HQ399_05350	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
HQ399_05350	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
HQ399_05355	COG0802	atpase or kinase
HQ399_05360	COG0860	N-Acetylmuramoyl-L-alanine amidase
HQ399_05365	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
HQ399_05370	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
HQ399_05375	COG1923	regulation of RNA biosynthetic process
HQ399_05380	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
HQ399_05385	COG0330	HflC and HflK could
HQ399_05390	COG0330	HflC and HflK could
HQ399_05395	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
HQ399_05400	COG0142	geranyltranstransferase activity
HQ399_05405	COG0261	This protein binds to 23S rRNA in the presence of protein L20
HQ399_05410	COG0211	Belongs to the bacterial ribosomal protein bL27 family
HQ399_05415	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
HQ399_05420	COG3314	Sporulation integral membrane protein YlbJ
HQ399_05425	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HQ399_05435	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
HQ399_05440	COG2967	ApaG domain
HQ399_05445	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
HQ399_05450	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
HQ399_05455	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
HQ399_05460	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
HQ399_05465	COG3178	'Phosphotransferase
HQ399_05470	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
HQ399_05475	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
HQ399_05480	COG2195	Cleaves the N-terminal amino acid of tripeptides
HQ399_05485	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
HQ399_05485	COG2755	lipolytic protein G-D-S-L family
HQ399_05625	COG4695	Portal protein
HQ399_05745	COG4974	Belongs to the 'phage' integrase family
HQ399_05750	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
HQ399_05755	COG1073	alpha beta
HQ399_05770	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
HQ399_05785	COG4628	conserved protein (DUF2132)
HQ399_05790	COG0688	phosphatidylethanolamine metabolic process
HQ399_05795	COG1162	GTPase activity
HQ399_05800	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
HQ399_05840	COG1278	Cold shock
HQ399_05850	COG0840	transmembrane signaling receptor activity
HQ399_05855	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
HQ399_05860	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
HQ399_05865	COG2252	PERMEase
HQ399_05875	COG0488	(ABC) transporter
HQ399_05890	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
HQ399_05895	COG0741	lytic transglycosylase activity
HQ399_05905	COG3416	Protein conserved in bacteria
HQ399_05925	COG4608	Belongs to the ABC transporter superfamily
HQ399_05930	COG0444	Belongs to the ABC transporter superfamily
HQ399_05935	COG4239	(ABC) transporter, permease
HQ399_05940	COG4174	ABC transporter (Permease)
HQ399_05950	COG0616	signal peptide processing
HQ399_05955	COG1902	pentaerythritol trinitrate reductase activity
HQ399_05955	COG0446	pyridine nucleotide-disulphide oxidoreductase
HQ399_05960	COG0778	Nitroreductase
HQ399_05965	COG0110	maltose O-acetyltransferase activity
HQ399_05970	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HQ399_05975	COG2264	protein methyltransferase activity
HQ399_05980	COG0604	alcohol dehydrogenase
HQ399_05985	COG0583	DNA-binding transcription factor activity
HQ399_05990	COG1263	PTS System
HQ399_05990	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HQ399_05990	COG2190	(PTS) system
HQ399_05995	COG4145	pantothenate transmembrane transporter activity
HQ399_06000	COG3924	membrane
HQ399_06005	COG0439	Biotin carboxylase
HQ399_06010	COG0511	ligase activity, forming carbon-carbon bonds
HQ399_06015	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
HQ399_06020	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
HQ399_06040	COG3381	protein complex oligomerization
HQ399_06055	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
HQ399_06065	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
HQ399_06070	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
HQ399_06070	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
HQ399_06090	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
HQ399_06095	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
HQ399_06100	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
HQ399_06110	COG4166	transmembrane transport
HQ399_06115	COG0601	transmembrane transport
HQ399_06125	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
HQ399_06130	COG0142	geranyltranstransferase activity
HQ399_06135	COG1722	exodeoxyribonuclease VII activity
HQ399_06140	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
HQ399_06145	COG1360	Flagellar Motor Protein
HQ399_06145	COG1360	Flagellar Motor Protein
HQ399_06160	COG1534	Rna-binding protein
HQ399_06165	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
HQ399_06175	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
HQ399_06180	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
HQ399_06185	COG0149	triose-phosphate isomerase activity
HQ399_06190	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
HQ399_06205	COG0779	Required for maturation of 30S ribosomal subunits
HQ399_06210	COG0195	Participates in both transcription termination and antitermination
HQ399_06215	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
HQ399_06220	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
HQ399_06225	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
HQ399_06230	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
HQ399_06235	COG1185	polyribonucleotide nucleotidyltransferase activity
HQ399_06240	COG2201	protein-glutamate methylesterase activity
HQ399_06245	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
HQ399_06255	COG0840	transmembrane signaling receptor activity
HQ399_06260	COG0835	chemotaxis
HQ399_06270	COG0643	Histidine kinase
HQ399_06270	COG2198	Histidine kinase
HQ399_06280	COG0745	RESPONSE REGULATOR receiver
HQ399_06290	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HQ399_06300	COG1280	lysine exporter protein (LysE YggA)
HQ399_06305	COG0826	peptidase U32
HQ399_06310	COG0737	Belongs to the 5'-nucleotidase family
HQ399_06330	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
HQ399_06355	COG0300	oxidoreductase activity
HQ399_06365	COG0840	transmembrane signaling receptor activity
HQ399_06395	COG0077	Prephenate dehydratase
HQ399_06395	COG1605	Chorismate mutase
HQ399_06425	COG3272	Protein of unknown function (DUF1722)
HQ399_06430	COG0789	Transcriptional regulator
HQ399_06435	COG0415	Belongs to the DNA photolyase family
HQ399_06445	COG0300	oxidoreductase activity
HQ399_06460	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
HQ399_06490	COG1477	protein flavinylation
HQ399_06495	COG2871	sodium ion transport
HQ399_06500	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
HQ399_06505	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
HQ399_06510	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
HQ399_06515	COG1805	sodium ion transport
HQ399_06520	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
HQ399_06525	COG0271	Belongs to the BolA IbaG family
HQ399_06530	COG2813	Specifically methylates the guanine in position
HQ399_06540	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
HQ399_06550	COG3248	Nucleoside-binding outer membrane protein
HQ399_06555	COG1666	GTP binding
HQ399_06560	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HQ399_06575	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HQ399_06580	COG0840	transmembrane signaling receptor activity
HQ399_06585	COG0583	DNA-binding transcription factor activity
HQ399_06595	COG2363	Small membrane protein
HQ399_06600	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
HQ399_06610	COG0473	3-isopropylmalate dehydrogenase activity
HQ399_06615	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HQ399_06620	COG1611	Belongs to the LOG family
HQ399_06635	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
HQ399_06635	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
HQ399_06645	COG5595	Zn-ribbon-containing, possibly nucleic-acid-binding protein (DUF2310)
HQ399_06670	COG3098	single-species biofilm formation
HQ399_06675	COG0564	pseudouridine synthase activity
HQ399_06695	COG1263	PTS System
HQ399_06695	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HQ399_06705	COG2171	N-acyltransferase activity
HQ399_06715	COG0024	Methionine aminopeptidase
HQ399_06720	COG0052	Belongs to the universal ribosomal protein uS2 family
HQ399_06725	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
HQ399_06730	COG0528	UMP kinase activity
HQ399_06735	COG0233	cytoplasmic translational termination
HQ399_06740	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
HQ399_06745	COG0575	Belongs to the CDS family
HQ399_06750	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
HQ399_06755	COG0750	zinc metalloprotease
HQ399_06770	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
HQ399_06775	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
HQ399_06780	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
HQ399_06785	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
HQ399_06790	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HQ399_06800	COG0825	malonyl-CoA metabolic process
HQ399_06810	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
HQ399_06815	COG1115	amino acid carrier protein
HQ399_06830	COG0714	Associated with various cellular activities
HQ399_06860	COG3104	oligopeptide transport
HQ399_06865	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
HQ399_06870	COG1678	Uncharacterized ACR, COG1678
HQ399_06880	COG0189	ligase activity
HQ399_06885	COG1385	rRNA (uridine-N3-)-methyltransferase activity
HQ399_06895	COG3091	SprT-like family
HQ399_06905	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
HQ399_06915	COG1063	alcohol dehydrogenase
HQ399_06920	COG0583	DNA-binding transcription factor activity
HQ399_06945	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
HQ399_06950	COG0739	heme binding
HQ399_06955	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
HQ399_06985	COG0814	amino acid
HQ399_07005	COG0531	amino acid
HQ399_07015	COG0488	(ABC) transporter
HQ399_07020	COG3710	Transcriptional regulator
HQ399_07030	COG0531	amino acid
HQ399_07035	COG1982	Orn Lys Arg decarboxylase major
HQ399_07040	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
HQ399_07050	COG3590	peptidase
HQ399_07060	COG2203	Gaf domain
HQ399_07060	COG2199	diguanylate cyclase activity
HQ399_07095	COG0366	Alpha amylase catalytic
HQ399_07110	COG0463	Glycosyl transferase, family 2
HQ399_07125	COG2989	Protein conserved in bacteria
HQ399_07130	COG3108	Peptidase M15
HQ399_07140	COG2860	membrane
HQ399_07150	COG1196	nuclear chromosome segregation
HQ399_07155	COG3115	cell septum assembly
HQ399_07230	COG2194	sulfuric ester hydrolase activity
HQ399_07240	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
HQ399_07245	COG5642	Protein of unknown function (DUF2384)
HQ399_07260	COG2916	Histone family protein nucleoid-structuring protein H-NS
HQ399_07335	COG1328	CTP reductase activity
HQ399_07340	COG0602	queuosine metabolic process
HQ399_07385	COG0281	malic enzyme
HQ399_07390	COG3290	protein histidine kinase activity
HQ399_07400	COG0697	spore germination
HQ399_07410	COG3706	GGDEF domain
HQ399_07415	COG0346	lactoylglutathione lyase activity
HQ399_07420	COG0745	RESPONSE REGULATOR receiver
HQ399_07425	COG5002	protein histidine kinase activity
HQ399_07450	COG3142	Participates in the control of copper homeostasis
HQ399_07455	COG0545	Peptidyl-prolyl cis-trans isomerase
HQ399_07470	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
HQ399_07490	COG0019	diaminopimelate decarboxylase activity
HQ399_07495	COG1115	amino acid carrier protein
HQ399_07500	COG2233	PERMEase
HQ399_07515	COG0534	Mate efflux family protein
HQ399_07525	COG0281	malic enzyme
HQ399_07535	COG2885	chlorophyll binding
HQ399_07535	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
HQ399_07555	COG0531	amino acid
HQ399_07560	COG1752	Esterase of the alpha-beta hydrolase superfamily
HQ399_07565	COG3706	GGDEF domain
HQ399_07570	COG1566	PFAM secretion protein HlyD family protein
HQ399_07575	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HQ399_07580	COG1032	radical SAM domain protein
HQ399_07610	COG0583	DNA-binding transcription factor activity
HQ399_07620	COG0673	inositol 2-dehydrogenase activity
HQ399_07625	COG2920	part of a sulfur-relay system
HQ399_07630	COG1289	transmembrane transporter activity
HQ399_07635	COG0670	Belongs to the BI1 family
HQ399_07650	COG3623	hexulose-6-phosphate isomerase
HQ399_07655	COG0561	phosphatase activity
HQ399_07680	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
HQ399_07690	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
HQ399_07700	COG3156	type II secretion system protein K
HQ399_07705	COG4795	General secretion pathway protein
HQ399_07710	COG2165	general secretion pathway protein
HQ399_07720	COG2165	general secretion pathway protein
HQ399_07725	COG1459	type II secretion system
HQ399_07730	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
HQ399_07740	COG3031	protein transport across the cell outer membrane
HQ399_07750	COG3267	Type II secretory pathway component ExeA
HQ399_07750	COG3409	Peptidoglycan-binding domain 1 protein
HQ399_07755	COG2770	Histidine kinase
HQ399_07755	COG3437	response regulator, receiver
HQ399_07770	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
HQ399_07775	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
HQ399_07780	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
HQ399_07790	COG2190	(PTS) system
HQ399_07795	COG3706	GGDEF domain
HQ399_07800	COG1196	nuclear chromosome segregation
HQ399_07800	COG3264	Mechanosensitive ion channel
HQ399_07805	COG0469	pyruvate kinase activity
HQ399_07815	COG3384	dioxygenase
HQ399_07820	COG0419	ATPase involved in DNA repair
HQ399_07825	COG0420	3'-5' exonuclease activity
HQ399_07835	COG2974	May be involved in recombination
HQ399_07845	COG1283	sodium-dependent phosphate transmembrane transporter activity
HQ399_07855	COG0531	amino acid
HQ399_07865	COG0531	amino acid
HQ399_07880	COG1917	Cupin 2, conserved barrel domain protein
HQ399_07880	COG1396	sequence-specific DNA binding
HQ399_07885	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
HQ399_07910	COG3152	Membrane
HQ399_07915	COG3161	chorismate lyase activity
HQ399_07940	COG1720	tRNA m6t6A37 methyltransferase activity
HQ399_07960	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
HQ399_07965	COG4988	ABC transporter
HQ399_07980	COG0745	RESPONSE REGULATOR receiver
HQ399_07990	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
HQ399_08005	COG0640	Transcriptional regulator
HQ399_08020	COG0798	PFAM Bile acid sodium symporter
HQ399_08025	COG1393	Belongs to the ArsC family
HQ399_08030	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
HQ399_08045	COG1988	membrane-bound metal-dependent
HQ399_08090	COG0159	tryptophan synthase activity
HQ399_08095	COG0133	tryptophan synthase activity
HQ399_08100	COG0135	phosphoribosylanthranilate isomerase activity
HQ399_08100	COG0134	indole-3-glycerol-phosphate synthase activity
HQ399_08105	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
HQ399_08110	COG0512	Glutamine amidotransferase of anthranilate synthase
HQ399_08110	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
HQ399_08115	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
HQ399_08125	COG0009	L-threonylcarbamoyladenylate synthase
HQ399_08135	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
HQ399_08165	COG1993	acr, cog1993
HQ399_08170	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HQ399_08180	COG1946	Acyl-CoA thioesterase
HQ399_08185	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
HQ399_08190	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
HQ399_08200	COG0083	homoserine kinase activity
HQ399_08205	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
HQ399_08215	COG1943	Transposase
HQ399_08230	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
HQ399_08255	COG1309	transcriptional regulator
HQ399_08260	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HQ399_08265	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HQ399_08300	COG0438	transferase activity, transferring glycosyl groups
HQ399_08305	COG1086	Polysaccharide biosynthesis protein
HQ399_08330	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
HQ399_08370	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
HQ399_08385	COG1091	dTDP-4-dehydrorhamnose reductase activity
HQ399_08390	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
HQ399_08415	COG1538	Outer membrane efflux protein
HQ399_08420	COG0577	efflux transmembrane transporter activity
HQ399_08420	COG1136	(ABC) transporter
HQ399_08425	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HQ399_08430	COG1227	inorganic diphosphatase activity
HQ399_08435	COG0497	DNA recombination
HQ399_08440	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
HQ399_08445	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
HQ399_08450	COG0443	Heat shock 70 kDa protein
HQ399_08455	COG0484	heat shock protein binding
HQ399_08460	COG1285	pathogenesis
HQ399_08500	COG5001	Diguanylate cyclase
HQ399_08505	COG0095	Lipoate-protein ligase
HQ399_08515	COG0702	epimerase
HQ399_08520	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
HQ399_08525	COG1454	alcohol dehydrogenase
HQ399_08535	COG0564	pseudouridine synthase activity
HQ399_08540	COG1957	nucleoside hydrolase
HQ399_08565	COG1280	lysine exporter protein (LysE YggA)
HQ399_08570	COG3263	regulation of cellular component size
HQ399_08580	COG3263	regulation of cellular component size
HQ399_08590	COG1876	peptidase activity
HQ399_08595	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
HQ399_08600	COG1393	Belongs to the ArsC family
HQ399_08610	COG3069	C4-dicarboxylate transmembrane transporter activity
HQ399_08625	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
HQ399_08635	COG0017	Asparaginyl-tRNA synthetase
HQ399_08650	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
HQ399_08655	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
HQ399_08660	COG0156	8-amino-7-oxononanoate synthase activity
HQ399_08665	COG1073	alpha beta
HQ399_08665	COG2226	methyltransferase
HQ399_08670	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
HQ399_08675	COG0501	Belongs to the peptidase M48B family
HQ399_08680	COG3217	Mosc domain protein beta barrel domain protein
HQ399_08680	COG0633	Ferredoxin
HQ399_08680	COG3217	Mosc domain protein beta barrel domain protein
HQ399_08680	COG0633	Ferredoxin
HQ399_08690	COG0674	pyruvate-flavodoxin oxidoreductase activity
HQ399_08690	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
HQ399_08690	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
HQ399_08690	COG1013	pyruvate-flavodoxin oxidoreductase activity
HQ399_08700	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
HQ399_08705	COG1607	acyl-coa hydrolase
HQ399_08715	COG3021	interspecies interaction between organisms
HQ399_08720	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
HQ399_08725	COG2027	D-alanyl-D-alanine carboxypeptidase
HQ399_08730	COG1061	Type III restriction enzyme res subunit
HQ399_08735	COG1566	PFAM secretion protein HlyD family protein
HQ399_08745	COG1966	Carbon starvation protein
HQ399_08750	COG3279	Response regulator of the LytR AlgR family
HQ399_08755	COG3275	phosphorelay sensor kinase activity
HQ399_08760	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
HQ399_08760	COG2199	diguanylate cyclase activity
HQ399_08770	COG1940	carbohydrate kinase activity
HQ399_08770	COG1846	Transcriptional regulator
HQ399_08775	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
HQ399_08780	COG0363	glucosamine-6-phosphate deaminase activity
HQ399_08785	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HQ399_08785	COG1263	PTS System
HQ399_08785	COG2190	(PTS) system
HQ399_08795	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
HQ399_08800	COG0735	belongs to the Fur family
HQ399_08810	COG0716	FMN binding
HQ399_08825	COG0596	Alpha beta hydrolase
HQ399_08830	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
HQ399_08835	COG0033	Phosphoglucomutase
HQ399_08840	COG2951	lytic endotransglycosylase activity
HQ399_08845	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HQ399_08850	COG4136	ATPase activity
HQ399_08855	COG4135	transport system, permease component
HQ399_08860	COG4134	Bacterial extracellular solute-binding protein
HQ399_08870	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
HQ399_08880	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
HQ399_08890	COG0729	surface antigen
HQ399_08895	COG2911	Protein conserved in bacteria
HQ399_08915	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
HQ399_08925	COG0741	lytic transglycosylase activity
HQ399_08935	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
HQ399_08940	COG4771	TonB-dependent receptor
HQ399_08945	COG1169	isochorismate synthase
HQ399_08950	COG1021	2,3-dihydroxybenzoate-AMP ligase
HQ399_08955	COG1535	isochorismatase
HQ399_08955	COG3433	isochorismatase activity
HQ399_08960	COG1028	Short-chain dehydrogenase reductase Sdr
HQ399_08965	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HQ399_08965	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
HQ399_08990	COG1278	Cold shock
HQ399_09015	COG4166	transmembrane transport
HQ399_09020	COG0697	spore germination
HQ399_09025	COG1349	DNA-binding transcription factor activity
HQ399_09030	COG1882	Formate acetyltransferase
HQ399_09035	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HQ399_09040	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
HQ399_09065	COG4166	transmembrane transport
HQ399_09070	COG0622	Phosphoesterase
HQ399_09085	COG1261	Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly
HQ399_09090	COG0835	chemotaxis
HQ399_09090	COG0784	Response regulator, receiver
HQ399_09095	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
HQ399_09100	COG1815	bacterial-type flagellum-dependent cell motility
HQ399_09110	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
HQ399_09120	COG4787	bacterial-type flagellum-dependent cell motility
HQ399_09130	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
HQ399_09135	COG1706	bacterial-type flagellum-dependent cell motility
HQ399_09140	COG1705	Flagellar rod assembly protein muramidase FlgJ
HQ399_09140	COG3951	Flagellar rod assembly protein muramidase FlgJ
HQ399_09155	COG2239	Acts as a magnesium transporter
HQ399_09165	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
HQ399_09170	COG2716	regulation of RNA biosynthetic process
HQ399_09195	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
HQ399_09200	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
HQ399_09205	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
HQ399_09210	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
HQ399_09230	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
HQ399_09250	COG0590	tRNA wobble adenosine to inosine editing
HQ399_09255	COG0573	inorganic phosphate transmembrane transporter activity
HQ399_09260	COG0581	inorganic phosphate transmembrane transporter activity
HQ399_09265	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
HQ399_09270	COG0704	Plays a role in the regulation of phosphate uptake
HQ399_09275	COG1253	flavin adenine dinucleotide binding
HQ399_09290	COG0531	amino acid
HQ399_09310	COG0765	amino acid transport
HQ399_09315	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HQ399_09320	COG2199	diguanylate cyclase activity
HQ399_09340	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
HQ399_09365	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
HQ399_09370	COG0477	Major facilitator Superfamily
HQ399_09375	COG0123	including yeast histone deacetylase and acetoin utilization protein
HQ399_09385	COG1199	ATP-dependent helicase activity
HQ399_09395	COG1605	Chorismate mutase
HQ399_09395	COG0287	Prephenate dehydrogenase
HQ399_09400	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
HQ399_09410	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
HQ399_09415	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
HQ399_09450	COG0537	adenosine 5'-monophosphoramidase activity
HQ399_09465	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
HQ399_09480	COG1301	dicarboxylic acid transport
HQ399_09490	COG2354	Protein conserved in bacteria
HQ399_09495	COG1164	Oligoendopeptidase f
HQ399_09500	COG2233	PERMEase
HQ399_09505	COG3150	esterase
HQ399_09510	COG1252	NADH dehydrogenase
HQ399_09520	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HQ399_09525	COG3300	MHYT domain
HQ399_09525	COG5001	Diguanylate cyclase
HQ399_09530	COG0446	pyridine nucleotide-disulphide oxidoreductase
HQ399_09540	COG2373	Large extracellular alpha-helical protein
HQ399_09545	COG4953	penicillin-binding protein 1C
HQ399_09555	COG0301	tRNA thio-modification
HQ399_09555	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HQ399_09615	COG2089	acid synthase
HQ399_09630	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
HQ399_09635	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
HQ399_09640	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
HQ399_09650	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
HQ399_09655	COG1086	Polysaccharide biosynthesis protein
HQ399_09660	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
HQ399_09670	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
HQ399_09685	COG0483	inositol monophosphate 1-phosphatase activity
HQ399_09695	COG0625	glutathione transferase activity
HQ399_09700	COG2814	Major facilitator Superfamily
HQ399_09705	COG0583	DNA-binding transcription factor activity
HQ399_09710	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
HQ399_09715	COG0243	molybdopterin cofactor binding
HQ399_09735	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
HQ399_09740	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
HQ399_09745	COG0404	The glycine cleavage system catalyzes the degradation of glycine
HQ399_09750	COG0509	glycine decarboxylation via glycine cleavage system
HQ399_09755	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
HQ399_09755	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
HQ399_09760	COG0840	transmembrane signaling receptor activity
HQ399_09765	COG0546	phosphoglycolate phosphatase activity
HQ399_09790	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
HQ399_09795	COG0574	Belongs to the PEP-utilizing enzyme family
HQ399_09795	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HQ399_09815	COG1464	Belongs to the NlpA lipoprotein family
HQ399_09820	COG3083	sulfuric ester hydrolase activity
HQ399_09825	COG3082	Protein of unknown function (DUF1414)
HQ399_09830	COG3081	Nucleoid-associated protein
HQ399_09840	COG1175	transmembrane transport
HQ399_09845	COG3833	ABC-type maltose transport systems, permease component
HQ399_09850	COG3842	ATPase activity
HQ399_09875	COG0425	Belongs to the sulfur carrier protein TusA family
HQ399_09880	COG4783	chaperone-mediated protein folding
HQ399_09890	COG1393	Belongs to the ArsC family
HQ399_09905	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
HQ399_09910	COG2431	L-lysine efflux transmembrane transporter activity
HQ399_09930	COG4160	amino acid transport
HQ399_09935	COG0564	pseudouridine synthase activity
HQ399_09950	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
HQ399_09960	COG0625	glutathione transferase activity
HQ399_09970	COG0367	asparagine synthase
HQ399_09980	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
HQ399_09980	COG4651	solute:proton antiporter activity
HQ399_09985	COG0647	UMP catabolic process
HQ399_10000	COG1902	pentaerythritol trinitrate reductase activity
HQ399_10005	COG1253	flavin adenine dinucleotide binding
HQ399_10015	COG0277	FAD linked oxidase domain protein
HQ399_10015	COG0247	lactate metabolic process
HQ399_10025	COG2050	protein possibly involved in aromatic compounds catabolism
HQ399_10040	COG5001	Diguanylate cyclase
HQ399_10040	COG3300	MHYT domain
HQ399_10045	COG2056	Na+-H+ antiporter family
HQ399_10050	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
HQ399_10055	COG0671	phosphoesterase, PA-phosphatase related
HQ399_10060	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
HQ399_10065	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
HQ399_10075	COG0101	tRNA pseudouridine synthase activity
HQ399_10080	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
HQ399_10085	COG0285	dihydrofolate synthase activity
HQ399_10090	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
HQ399_10095	COG0393	Putative heavy-metal-binding
HQ399_10105	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
HQ399_10105	COG1648	precorrin-2 dehydrogenase activity
HQ399_10125	COG4667	esterase of the alpha-beta hydrolase superfamily
HQ399_10130	COG1619	proteins homologs of microcin C7 resistance protein MccF
HQ399_10135	COG1368	sulfuric ester hydrolase activity
HQ399_10145	COG0527	aspartate kinase activity
HQ399_10150	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
HQ399_10150	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
HQ399_10155	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HQ399_10175	COG0596	Alpha beta hydrolase
HQ399_10195	COG2814	Major facilitator Superfamily
HQ399_10215	COG0672	)-iron permease
HQ399_10245	COG0659	secondary active sulfate transmembrane transporter activity
HQ399_10320	COG3829	transcription factor binding
HQ399_10355	COG4104	PAAR repeat-containing protein
HQ399_10380	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
HQ399_10385	COG0326	Molecular chaperone. Has ATPase activity
HQ399_10390	COG4172	Belongs to the ABC transporter superfamily
HQ399_10420	COG1842	Phage shock protein A
HQ399_10435	COG3106	COG3106 Predicted ATPase
HQ399_10440	COG3768	UPF0283 membrane protein
HQ399_10450	COG2154	pterin-4-alpha-carbinolamine dehydratase
HQ399_10470	COG2885	chlorophyll binding
HQ399_10475	COG0861	Integral membrane protein TerC family
HQ399_10490	COG1022	Amp-dependent synthetase and ligase
HQ399_10505	COG2910	NAD(P)H-binding
HQ399_10510	COG0583	DNA-binding transcription factor activity
HQ399_10515	COG2271	Major facilitator Superfamily
HQ399_10525	COG1335	isochorismatase
HQ399_10535	COG0583	DNA-binding transcription factor activity
HQ399_10540	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
HQ399_10550	COG0583	DNA-binding transcription factor activity
HQ399_10555	COG2723	6-phospho-beta-galactosidase activity
HQ399_10560	COG1944	ATP diphosphatase activity
HQ399_10565	COG2116	formate transmembrane transporter activity
HQ399_10570	COG1882	Formate acetyltransferase
HQ399_10575	COG2983	Belongs to the UPF0260 family
HQ399_10590	COG0058	SHG alpha-glucan phosphorylase activity
HQ399_10595	COG0471	metal ion transport
HQ399_10600	COG3118	belongs to the thioredoxin family
HQ399_10605	COG2205	protein histidine kinase activity
HQ399_10605	COG3437	response regulator, receiver
HQ399_10605	COG3850	Histidine kinase
HQ399_10605	COG4999	Histidine kinase
HQ399_10610	COG1132	(ABC) transporter
HQ399_10615	COG1132	(ABC) transporter
HQ399_10625	COG2501	S4 domain
HQ399_10640	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
HQ399_10695	COG2009	succinate dehydrogenase
HQ399_10700	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
HQ399_10705	COG1053	succinate dehydrogenase
HQ399_10715	COG0567	Dehydrogenase, E1 component
HQ399_10720	COG0508	dehydrogenase complex catalyzes the overall conversion of
HQ399_10725	COG0045	succinate-CoA ligase (ADP-forming) activity
HQ399_10755	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
HQ399_10765	COG3842	ATPase activity
HQ399_10775	COG1840	ABC-type Fe3 transport system, periplasmic component
HQ399_10785	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
HQ399_10795	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
HQ399_10800	COG3088	subunit of a heme lyase
HQ399_10800	COG4235	cytochrome complex assembly
HQ399_10810	COG1138	Cytochrome C-type biogenesis protein
HQ399_10815	COG3301	Polysulphide reductase, NrfD
HQ399_10820	COG0437	4 iron, 4 sulfur cluster binding
HQ399_10825	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
HQ399_10840	COG0247	lactate metabolic process
HQ399_10845	COG3075	Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses fumarate or nitrate as electron acceptor
HQ399_10850	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
HQ399_10875	COG3148	PFAM DTW domain containing protein
HQ399_10880	COG0730	response to heat
HQ399_10885	COG0583	DNA-binding transcription factor activity
HQ399_10900	COG3593	DNA synthesis involved in DNA repair
HQ399_10960	COG1011	Hydrolase
HQ399_10975	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HQ399_10980	COG2832	Protein of unknown function (DUF454)
HQ399_10985	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
HQ399_10995	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
HQ399_11015	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
HQ399_11020	COG0583	DNA-binding transcription factor activity
HQ399_11030	COG1560	Kdo2-lipid A biosynthetic process
HQ399_11035	COG1560	Kdo2-lipid A biosynthetic process
HQ399_11055	COG0417	DNA replication proofreading
HQ399_11070	COG1451	nucleotide metabolic process
HQ399_11085	COG3069	C4-dicarboxylate transmembrane transporter activity
HQ399_11100	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
HQ399_11100	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
HQ399_11105	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
HQ399_11110	COG0569	domain protein
HQ399_11110	COG2985	domain, Protein
HQ399_11120	COG0556	nucleotide-excision repair
HQ399_11130	COG0586	Pfam SNARE associated Golgi protein
HQ399_11135	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
HQ399_11140	COG3067	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
HQ399_11165	COG3829	transcription factor binding
HQ399_11195	COG0534	Mate efflux family protein
HQ399_11210	COG0307	riboflavin synthase, alpha
HQ399_11225	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
HQ399_11230	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
HQ399_11235	COG0697	spore germination
HQ399_11240	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
HQ399_11275	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
HQ399_11280	COG3099	Belongs to the UPF0263 family
HQ399_11285	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
HQ399_11290	COG2894	cell division
HQ399_11295	COG0850	regulation of cytokinetic process
HQ399_11300	COG3100	YcgL domain-containing protein
HQ399_11310	COG2824	Alkylphosphonate utilization operon protein PhnA
HQ399_11325	COG3706	GGDEF domain
HQ399_11330	COG2840	Smr protein MutS2
HQ399_11335	COG2890	protein-(glutamine-N5) methyltransferase activity
HQ399_11340	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
HQ399_11350	COG0513	Belongs to the DEAD box helicase family
HQ399_11355	COG3788	relative of glutathione S-transferase, MAPEG superfamily
HQ399_11370	COG0814	amino acid
HQ399_11375	COG1609	Transcriptional regulator
HQ399_11380	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
HQ399_11380	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
HQ399_11385	COG1105	Belongs to the carbohydrate kinase PfkB family
HQ399_11390	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HQ399_11390	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HQ399_11390	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
HQ399_11395	COG3313	Fe-S protein
HQ399_11400	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
HQ399_11405	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
HQ399_11410	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HQ399_11415	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HQ399_11425	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
HQ399_11435	COG0366	Alpha amylase catalytic
HQ399_11455	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
HQ399_11460	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
HQ399_11465	COG0291	Belongs to the bacterial ribosomal protein bL35 family
HQ399_11470	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
HQ399_11475	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
HQ399_11480	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
HQ399_11485	COG0072	phenylalanine-tRNA ligase activity
HQ399_11485	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HQ399_11490	COG0776	regulation of translation
HQ399_11495	COG0784	Response regulator, receiver
HQ399_11495	COG2205	protein histidine kinase activity
HQ399_11515	COG1609	Transcriptional regulator
HQ399_11520	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HQ399_11525	COG1879	ABC-type sugar transport system periplasmic component
HQ399_11530	COG1172	Belongs to the binding-protein-dependent transport system permease family
HQ399_11535	COG1129	ABC transporter
HQ399_11540	COG1869	D-ribose catabolic process
HQ399_11545	COG0625	glutathione transferase activity
HQ399_11555	COG1177	transmembrane transport
HQ399_11580	COG0037	tRNA processing
HQ399_11585	COG0589	response to stress
HQ399_11590	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
HQ399_11615	COG2010	Cytochrome c
HQ399_11630	COG3278	Belongs to the heme-copper respiratory oxidase family
HQ399_11645	COG1956	GAF domain-containing protein
HQ399_11650	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
HQ399_11660	COG0308	aminopeptidase N
HQ399_11670	COG2902	Dehydrogenase
HQ399_11675	COG0167	dihydroorotate dehydrogenase activity
HQ399_11685	COG0840	transmembrane signaling receptor activity
HQ399_11690	COG3706	GGDEF domain
HQ399_11690	COG2203	Gaf domain
HQ399_11690	COG4251	negative regulation of phosphorylation
HQ399_11690	COG5001	Diguanylate cyclase
HQ399_11695	COG2201	protein-glutamate methylesterase activity
HQ399_11705	COG0835	chemotaxis
HQ399_11710	COG3290	protein histidine kinase activity
HQ399_11710	COG0840	transmembrane signaling receptor activity
HQ399_11730	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
HQ399_11730	COG0116	Belongs to the methyltransferase superfamily
HQ399_11740	COG0488	(ABC) transporter
HQ399_11750	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
HQ399_11755	COG1067	ATP-dependent peptidase activity
HQ399_11770	COG3141	response to X-ray
HQ399_11780	COG4221	oxidoreductase activity
HQ399_11805	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HQ399_11825	COG0372	Belongs to the citrate synthase family
HQ399_11830	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
HQ399_11840	COG2995	paraquat-inducible protein a
HQ399_11845	COG3008	intermembrane lipid transfer
HQ399_11850	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
HQ399_11850	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
HQ399_11865	COG0084	hydrolase, TatD family'
HQ399_11870	COG0470	DNA polymerase III
HQ399_11875	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
HQ399_11880	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
HQ399_11885	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
HQ399_11895	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
HQ399_11900	COG1028	Short-chain dehydrogenase reductase Sdr
HQ399_11910	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HQ399_11915	COG0416	fatty acid biosynthetic process
HQ399_11920	COG0333	Belongs to the bacterial ribosomal protein bL32 family
HQ399_11925	COG1399	metal-binding, possibly nucleic acid-binding protein
HQ399_11930	COG0424	maF-like protein
HQ399_11940	COG0564	pseudouridine synthase activity
HQ399_11945	COG1530	ribonuclease E activity
HQ399_11950	COG0306	phosphate transporter
HQ399_11955	COG0717	Belongs to the dCTP deaminase family
HQ399_11960	COG0572	uridine kinase
HQ399_11965	COG0489	protein tyrosine kinase activity
HQ399_11970	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HQ399_11970	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HQ399_11980	COG1254	Belongs to the acylphosphatase family
HQ399_11985	COG0840	transmembrane signaling receptor activity
HQ399_11990	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
HQ399_12000	COG0709	Synthesizes selenophosphate from selenide and ATP
HQ399_12005	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
HQ399_12010	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
HQ399_12020	COG0318	PFAM AMP-dependent synthetase and ligase
HQ399_12025	COG2267	carboxylic ester hydrolase activity
HQ399_12035	COG1214	PFAM Peptidase M22, glycoprotease
HQ399_12040	COG1199	ATP-dependent helicase activity
HQ399_12050	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
HQ399_12055	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
HQ399_12060	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
HQ399_12065	COG0131	Imidazoleglycerol-phosphate dehydratase
HQ399_12065	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
HQ399_12070	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
HQ399_12075	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
HQ399_12080	COG0107	imidazoleglycerol-phosphate synthase activity
HQ399_12090	COG2199	diguanylate cyclase activity
HQ399_12100	COG1288	antiporter activity
HQ399_12110	COG3134	Outer membrane lipoprotein
HQ399_12115	COG2080	2 iron, 2 sulfur cluster binding
HQ399_12120	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
HQ399_12125	COG1529	Aldehyde oxidase and xanthine dehydrogenase
HQ399_12130	COG2252	PERMEase
HQ399_12135	COG0402	S-adenosylhomocysteine deaminase activity
HQ399_12145	COG1529	Aldehyde oxidase and xanthine dehydrogenase
HQ399_12145	COG2080	2 iron, 2 sulfur cluster binding
HQ399_12150	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
HQ399_12155	COG0402	S-adenosylhomocysteine deaminase activity
HQ399_12160	COG0493	'glutamate synthase
HQ399_12160	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
HQ399_12170	COG2068	MobA-Related Protein
HQ399_12175	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
HQ399_12180	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
HQ399_12180	COG3608	succinylglutamate desuccinylase aspartoacylase
HQ399_12185	COG0697	spore germination
HQ399_12190	COG0549	Belongs to the carbamate kinase family
HQ399_12200	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
HQ399_12205	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
HQ399_12210	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
HQ399_12235	COG0242	peptide deformylase activity
HQ399_12245	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
HQ399_12250	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
HQ399_12255	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
HQ399_12265	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
HQ399_12270	COG1434	Gram-negative-bacterium-type cell wall biogenesis
HQ399_12280	COG0205	6-phosphofructokinase activity
HQ399_12285	COG1301	dicarboxylic acid transport
HQ399_12290	COG3123	guanosine phosphorylase activity
HQ399_12295	COG1760	l-serine dehydratase
HQ399_12300	COG1760	l-serine dehydratase
HQ399_12320	COG0814	amino acid
HQ399_12325	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
HQ399_12330	COG0514	ATP-dependent DNA helicase (RecQ)
HQ399_12335	COG2766	serine protein kinase
HQ399_12340	COG2718	Belongs to the UPF0229 family
HQ399_12345	COG2719	SpoVR family
HQ399_12350	COG1024	Enoyl-CoA hydratase
HQ399_12350	COG1250	3-hydroxyacyl-CoA dehydrogenase
HQ399_12355	COG0183	Belongs to the thiolase family
HQ399_12360	COG0714	Associated with various cellular activities
HQ399_12390	COG1595	DNA-templated transcription, initiation
HQ399_12400	COG2067	long-chain fatty acid transport protein
HQ399_12405	COG2067	long-chain fatty acid transport protein
HQ399_12410	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
HQ399_12425	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
HQ399_12435	COG1643	Atp-dependent helicase
HQ399_12440	COG0517	IMP dehydrogenase activity
HQ399_12440	COG0617	tRNA 3'-terminal CCA addition
HQ399_12440	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
HQ399_12445	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
HQ399_12455	COG0438	transferase activity, transferring glycosyl groups
HQ399_12460	COG0297	glycogen (starch) synthase activity
HQ399_12475	COG0110	maltose O-acetyltransferase activity
HQ399_12480	COG0438	transferase activity, transferring glycosyl groups
HQ399_12525	COG0438	transferase activity, transferring glycosyl groups
HQ399_12530	COG1215	transferase activity, transferring glycosyl groups
HQ399_12535	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
HQ399_12575	COG0784	Response regulator, receiver
HQ399_12575	COG2205	protein histidine kinase activity
HQ399_12580	COG2925	Exonuclease
HQ399_12590	COG3345	alpha-galactosidase
HQ399_12595	COG1380	Effector of murein hydrolase LrgA
HQ399_12600	COG1346	cytolysis
HQ399_12605	COG0295	cytidine deaminase activity
HQ399_12610	COG3033	Beta-eliminating lyase
HQ399_12620	COG3046	protein related to deoxyribodipyrimidine photolyase
HQ399_12625	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
HQ399_12635	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
HQ399_12660	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
HQ399_12675	COG3158	transport of potassium into the cell
HQ399_12680	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
HQ399_12685	COG0651	ATP synthesis coupled electron transport
HQ399_12690	COG0650	Formate hydrogenlyase subunit 4
HQ399_12695	COG3261	NADH dehydrogenase
HQ399_12695	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
HQ399_12700	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
HQ399_12705	COG3260	NADH ubiquinone oxidoreductase 20
HQ399_12725	COG1921	L-seryl-tRNASec selenium transferase activity
HQ399_12735	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
HQ399_12740	COG0298	carbon dioxide binding
HQ399_12750	COG0309	Hydrogenase expression formation protein (HypE)
HQ399_12755	COG0375	protein maturation
HQ399_12760	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
HQ399_12765	COG3842	ATPase activity
HQ399_12775	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
HQ399_12790	COG1773	rubredoxin
HQ399_12795	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
HQ399_12800	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
HQ399_12805	COG5557	Pfam Polysulphide reductase, NrfD
HQ399_12810	COG0437	4 iron, 4 sulfur cluster binding
HQ399_12815	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
HQ399_12835	COG0730	response to heat
HQ399_12845	COG1028	Short-chain dehydrogenase reductase Sdr
HQ399_12855	COG1024	Enoyl-CoA hydratase
HQ399_12860	COG1024	Enoyl-CoA hydratase
HQ399_12865	COG1960	acyl-CoA dehydrogenase activity
HQ399_12870	COG1960	acyl-CoA dehydrogenase activity
HQ399_12875	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
HQ399_12880	COG1024	Enoyl-CoA hydratase
HQ399_12910	COG1584	GPR1 FUN34 yaaH family protein
HQ399_12915	COG3228	Belongs to the MtfA family
HQ399_12925	COG1115	amino acid carrier protein
HQ399_12930	COG1024	Enoyl-CoA hydratase
HQ399_12945	COG3162	membrane
HQ399_12950	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HQ399_12955	COG0488	(ABC) transporter
HQ399_12960	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
HQ399_12965	COG0776	regulation of translation
HQ399_12970	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
HQ399_12975	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
HQ399_12980	COG0740	serine-type endopeptidase activity
HQ399_12985	COG0544	peptidyl-prolyl cis-trans isomerase activity
HQ399_12995	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
HQ399_13000	COG4591	ABC-type transport system involved in lipoprotein release permease component
HQ399_13005	COG1136	(ABC) transporter
HQ399_13010	COG4591	ABC-type transport system involved in lipoprotein release permease component
HQ399_13020	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
HQ399_13025	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
HQ399_13030	COG4166	transmembrane transport
HQ399_13035	COG0697	spore germination
HQ399_13045	COG2062	phosphohistidine phosphatase, SixA
HQ399_13080	COG0518	GMP synthase (glutamine-hydrolyzing) activity
HQ399_13080	COG0519	Catalyzes the synthesis of GMP from XMP
HQ399_13085	COG0517	IMP dehydrogenase activity
HQ399_13085	COG0516	GMP reductase activity
HQ399_13095	COG1570	exodeoxyribonuclease VII activity
HQ399_13100	COG2188	Transcriptional regulator
HQ399_13105	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
HQ399_13105	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HQ399_13105	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HQ399_13110	COG0383	alpha-mannosidase activity
HQ399_13115	COG1181	Belongs to the D-alanine--D-alanine ligase family
HQ399_13125	COG0386	Belongs to the glutathione peroxidase family
HQ399_13130	COG0513	Belongs to the DEAD box helicase family
HQ399_13145	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
HQ399_13150	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
HQ399_13205	COG5001	Diguanylate cyclase
HQ399_13205	COG3300	MHYT domain
HQ399_13220	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HQ399_13230	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
HQ399_13235	COG0563	adenylate kinase activity
HQ399_13245	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
HQ399_13250	COG1286	toxin biosynthetic process
HQ399_13255	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
HQ399_13260	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
HQ399_13265	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
HQ399_13270	COG0531	amino acid
HQ399_13270	COG1674	ftsk spoiiie
HQ399_13280	COG0686	Belongs to the AlaDH PNT family
HQ399_13285	COG0492	ferredoxin-NADP+ reductase activity
HQ399_13290	COG3706	GGDEF domain
HQ399_13295	COG3134	Outer membrane lipoprotein
HQ399_13300	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
HQ399_13305	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
HQ399_13310	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
HQ399_13315	COG0542	response to heat
HQ399_13320	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
HQ399_13325	COG1278	Cold shock
HQ399_13330	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
HQ399_13350	COG0745	RESPONSE REGULATOR receiver
HQ399_13355	COG2205	protein histidine kinase activity
HQ399_13365	COG0392	lysyltransferase activity
HQ399_13365	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
HQ399_13375	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
HQ399_13405	COG1435	thymidine kinase activity
HQ399_13410	COG1757	Na H antiporter
HQ399_13415	COG2916	Histone family protein nucleoid-structuring protein H-NS
HQ399_13420	COG2096	Adenosyltransferase
HQ399_13425	COG3530	Putative quorum-sensing-regulated virulence factor
HQ399_13430	COG0602	queuosine metabolic process
HQ399_13435	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
HQ399_13455	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
HQ399_13465	COG0776	regulation of translation
HQ399_13470	COG0539	negative regulation of cytoplasmic translation
HQ399_13475	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
HQ399_13480	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
HQ399_13485	COG0583	DNA-binding transcription factor activity
HQ399_13495	COG2814	Major facilitator Superfamily
HQ399_13515	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
HQ399_13520	COG5001	Diguanylate cyclase
HQ399_13520	COG3300	MHYT domain
HQ399_13525	COG0583	DNA-binding transcription factor activity
HQ399_13530	COG3437	response regulator, receiver
HQ399_13555	COG4989	oxidoreductase activity
HQ399_13560	COG0724	RNA recognition motif
HQ399_13570	COG1126	abc transporter atp-binding protein
HQ399_13575	COG0765	amino acid transport
HQ399_13580	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HQ399_13585	COG4597	amino acid ABC transporter
HQ399_13590	COG3770	Murein endopeptidase that cleaves the D-alanyl-meso-2,6- diamino-pimelyl amide bond that connects peptidoglycan strands. Likely plays a role in the removal of murein from the sacculus
HQ399_13600	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
HQ399_13615	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
HQ399_13625	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
HQ399_13630	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
HQ399_13635	COG0649	NAD binding
HQ399_13635	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
HQ399_13650	COG1034	ATP synthesis coupled electron transport
HQ399_13655	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
HQ399_13660	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
HQ399_13665	COG0839	Belongs to the complex I subunit 6 family
HQ399_13670	COG0713	ATP synthesis coupled electron transport
HQ399_13680	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
HQ399_13685	COG1007	ATP synthesis coupled electron transport
HQ399_13700	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
HQ399_13700	COG2199	diguanylate cyclase activity
HQ399_13705	COG0047	phosphoribosylformylglycinamidine synthase activity
HQ399_13705	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HQ399_13710	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
HQ399_13715	COG1645	bacterial-type flagellum-dependent swarming motility
HQ399_13720	COG1160	GTP binding
HQ399_13725	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
HQ399_13730	COG2976	Protein conserved in bacteria
HQ399_13735	COG0124	histidyl-tRNA synthetase
HQ399_13755	COG0820	rRNA (adenine-C2-)-methyltransferase activity
HQ399_13760	COG0105	UTP biosynthetic process
HQ399_13765	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
HQ399_13775	COG0633	Ferredoxin
HQ399_13780	COG0443	Heat shock 70 kDa protein
HQ399_13785	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
HQ399_13795	COG0822	iron-sulfur transferase activity
HQ399_13800	COG1104	cysteine desulfurase activity
HQ399_13805	COG1959	2 iron, 2 sulfur cluster binding
HQ399_13820	COG3154	lipid carrier protein
HQ399_13825	COG0826	peptidase U32
HQ399_13830	COG0826	peptidase U32
HQ399_13845	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
HQ399_13850	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
HQ399_13855	COG1862	Preprotein translocase
HQ399_13860	COG0343	queuine tRNA-ribosyltransferase activity
HQ399_13865	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
HQ399_13870	COG0517	IMP dehydrogenase activity
HQ399_13870	COG1125	glycine betaine transport
HQ399_13880	COG3634	alkyl hydroperoxide reductase activity
HQ399_13925	COG1242	4 iron, 4 sulfur cluster binding
HQ399_13930	COG0070	glutamate synthase
HQ399_13930	COG0069	glutamate synthase activity
HQ399_13930	COG0067	glutamate synthase
HQ399_13935	COG0493	'glutamate synthase
HQ399_13940	COG1126	abc transporter atp-binding protein
HQ399_13945	COG0765	amino acid transport
HQ399_13950	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HQ399_13965	COG0513	Belongs to the DEAD box helicase family
HQ399_13980	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
HQ399_13990	COG0023	Translation Initiation Factor
HQ399_13995	COG2119	membrane
HQ399_14050	COG0215	cysteine-tRNA ligase activity
HQ399_14055	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
HQ399_14065	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
HQ399_14075	COG2261	transglycosylase associated protein
HQ399_14080	COG0642	Histidine kinase
HQ399_14125	COG0322	excinuclease ABC activity
HQ399_14130	COG2197	response regulator
HQ399_14135	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
HQ399_14140	COG2835	tetraacyldisaccharide 4'-kinase activity
HQ399_14145	COG1663	tetraacyldisaccharide 4'-kinase activity
HQ399_14170	COG1448	Aminotransferase
HQ399_14180	COG0583	DNA-binding transcription factor activity
HQ399_14185	COG3085	chromosome segregation
HQ399_14190	COG4574	serine-type endopeptidase inhibitor activity
HQ399_14195	COG0584	glycerophosphoryl diester phosphodiesterase
HQ399_14205	COG1349	DNA-binding transcription factor activity
HQ399_14210	COG2271	Major facilitator Superfamily
HQ399_14215	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
HQ399_14220	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
HQ399_14225	COG0840	transmembrane signaling receptor activity
HQ399_14235	COG0583	DNA-binding transcription factor activity
HQ399_14255	COG0656	L-ascorbic acid biosynthetic process
HQ399_14260	COG2814	Major facilitator Superfamily
HQ399_14265	COG2249	NAD(P)H dehydrogenase (quinone) activity
HQ399_14280	COG3220	belongs to the UPF0276 family
HQ399_14300	COG1294	oxidase, subunit
HQ399_14310	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HQ399_14315	COG2979	Protein of unknown function (DUF533)
HQ399_14330	COG0583	DNA-binding transcription factor activity
HQ399_14340	COG2807	transmembrane transport
HQ399_14345	COG1187	pseudouridine synthase activity
HQ399_14350	COG0346	lactoylglutathione lyase activity
HQ399_14360	COG1403	HNH endonuclease
HQ399_14365	COG4657	Part of a membrane complex involved in electron transport
HQ399_14370	COG2878	Part of a membrane complex involved in electron transport
HQ399_14380	COG4658	electron transport chain
HQ399_14385	COG4659	FMN binding
HQ399_14390	COG4660	Part of a membrane complex involved in electron transport
HQ399_14395	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
HQ399_14400	COG0346	lactoylglutathione lyase activity
HQ399_14415	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
HQ399_14430	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
HQ399_14435	COG0505	Belongs to the CarA family
HQ399_14440	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
HQ399_14450	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
HQ399_14455	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
HQ399_14460	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
HQ399_14465	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
HQ399_14470	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
HQ399_14475	COG4138	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system
HQ399_14480	COG4139	cobalamin transport
HQ399_14500	COG2020	methyltransferase activity
HQ399_14505	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HQ399_14510	COG0861	Integral membrane protein TerC family
HQ399_14525	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
HQ399_14530	COG0601	transmembrane transport
HQ399_14540	COG2095	MarC family integral membrane protein
HQ399_14545	COG1454	alcohol dehydrogenase
HQ399_14545	COG1012	belongs to the aldehyde dehydrogenase family
HQ399_14550	COG0217	transcriptional regulatory protein
HQ399_14555	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
HQ399_14565	COG1801	Protein of unknown function DUF72
HQ399_14570	COG4106	trans-aconitate 2-methyltransferase activity
HQ399_14575	COG0500	methyltransferase
HQ399_14595	COG0450	alkyl hydroperoxide reductase
HQ399_14600	COG0583	DNA-binding transcription factor activity
HQ399_14605	COG0791	NLP P60 protein
HQ399_14615	COG0583	DNA-binding transcription factor activity
HQ399_14620	COG2610	gluconate transmembrane transporter activity
HQ399_14625	COG3048	D-serine ammonia-lyase activity
HQ399_14630	COG0538	isocitrate dehydrogenase activity
HQ399_14635	COG2207	Transcriptional regulator
HQ399_14660	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HQ399_14675	COG3152	Membrane
HQ399_14680	COG2814	Major facilitator Superfamily
HQ399_14685	COG0109	protoheme IX farnesyltransferase activity
HQ399_14690	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
HQ399_14695	COG1845	cytochrome c oxidase, subunit III
HQ399_14700	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
HQ399_14705	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
HQ399_14740	COG1309	transcriptional regulator
HQ399_14750	COG1454	alcohol dehydrogenase
HQ399_14770	COG0534	Mate efflux family protein
HQ399_14780	COG2841	Protein conserved in bacteria
HQ399_14785	COG3132	Protein of unknown function, DUF480
HQ399_14815	COG0708	Exodeoxyribonuclease III
HQ399_14835	COG1122	ATPase activity
HQ399_14840	COG1122	ATPase activity
HQ399_14860	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HQ399_14865	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HQ399_14875	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
HQ399_14880	COG1120	ATPase activity
HQ399_14885	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HQ399_14890	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HQ399_14895	COG2375	cellular response to nickel ion
HQ399_14900	COG0784	Response regulator, receiver
HQ399_14900	COG3437	response regulator, receiver
HQ399_14910	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
HQ399_14915	COG0328	RNA-DNA hybrid ribonuclease activity
HQ399_14920	COG2226	methyltransferase
HQ399_14925	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
HQ399_14930	COG0741	lytic transglycosylase activity
HQ399_14930	COG1388	LysM domain
HQ399_14955	COG5002	protein histidine kinase activity
HQ399_14960	COG0745	RESPONSE REGULATOR receiver
HQ399_14965	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HQ399_14970	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HQ399_14980	COG1376	ErfK ybiS ycfS ynhG family protein
HQ399_14980	COG1388	LysM domain
HQ399_14990	COG0471	metal ion transport
HQ399_15000	COG3129	Specifically methylates the adenine in position 1618 of 23S rRNA
HQ399_15005	COG0791	NLP P60 protein
HQ399_15025	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
HQ399_15030	COG0788	formyltetrahydrofolate deformylase activity
HQ399_15055	COG0741	lytic transglycosylase activity
HQ399_15055	COG0739	heme binding
HQ399_15055	COG1196	nuclear chromosome segregation
HQ399_15060	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
HQ399_15070	COG0436	Aminotransferase
HQ399_15075	COG1288	antiporter activity
HQ399_15080	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
HQ399_15085	COG1879	ABC-type sugar transport system periplasmic component
HQ399_15095	COG0406	alpha-ribazole phosphatase activity
HQ399_15100	COG2964	Protein conserved in bacteria
HQ399_15105	COG3681	Belongs to the UPF0597 family
HQ399_15115	COG0814	amino acid
HQ399_15135	COG1166	arginine decarboxylase activity
HQ399_15140	COG2195	Cleaves the N-terminal amino acid of tripeptides
HQ399_15170	COG0583	DNA-binding transcription factor activity
HQ399_15180	COG2759	Belongs to the formate--tetrahydrofolate ligase family
HQ399_15185	COG0840	transmembrane signaling receptor activity
HQ399_15190	COG0302	gtp cyclohydrolase
HQ399_15195	COG0303	'Molybdopterin
HQ399_15200	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
HQ399_15220	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
HQ399_15235	COG0314	molybdopterin synthase activity
HQ399_15240	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
HQ399_15245	COG0315	cyclic pyranopterin monophosphate synthase activity
HQ399_15250	COG0521	Mo-molybdopterin cofactor biosynthetic process
HQ399_15255	COG3005	denitrification pathway
HQ399_15265	COG0348	domain, Protein
HQ399_15270	COG0437	4 iron, 4 sulfur cluster binding
HQ399_15275	COG0243	molybdopterin cofactor binding
HQ399_15285	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
HQ399_15290	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
HQ399_15295	COG3850	Histidine kinase
HQ399_15300	COG2197	response regulator
HQ399_15330	COG0121	glutamine amidotransferase
HQ399_15335	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
HQ399_15340	COG1960	acyl-CoA dehydrogenase activity
HQ399_15345	COG1473	amidohydrolase
HQ399_15350	COG2914	Belongs to the UPF0125 (RnfH) family
HQ399_15355	COG2867	negative regulation of translational initiation
HQ399_15360	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
HQ399_15370	COG4974	Belongs to the 'phage' integrase family
HQ399_15425	COG0477	Major facilitator Superfamily
HQ399_15425	COG2814	Major facilitator Superfamily
HQ399_15430	COG0457	Tetratricopeptide repeat
HQ399_15435	COG1940	carbohydrate kinase activity
HQ399_15440	COG3383	formate dehydrogenase (NAD+) activity
HQ399_15485	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
HQ399_15495	COG1960	acyl-CoA dehydrogenase activity
HQ399_15500	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
HQ399_15515	COG1317	bacterial-type flagellum organization
HQ399_15605	COG0457	Tetratricopeptide repeat
HQ399_15675	COG4790	Type iii secretion
HQ399_15680	COG4794	Type iii secretion
HQ399_15685	COG4791	protein targeting
HQ399_15690	COG4792	protein secretion
HQ399_15705	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
HQ399_15710	COG1263	PTS System
HQ399_15710	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HQ399_15715	COG1609	Transcriptional regulator
HQ399_15725	COG4821	SIS domain
HQ399_15740	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HQ399_15740	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HQ399_15740	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
HQ399_15750	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HQ399_15760	COG1187	pseudouridine synthase activity
HQ399_15765	COG1051	belongs to the nudix hydrolase family
HQ399_15770	COG0482	sulfurtransferase activity
HQ399_15775	COG2915	High frequency lysogenization protein hflD homolog
HQ399_15780	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
HQ399_15785	COG2850	peptidyl-arginine hydroxylation
HQ399_15800	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
HQ399_15815	COG1397	ADP-ribosylglycohydrolase
HQ399_15825	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HQ399_15845	COG0625	glutathione transferase activity
HQ399_15850	COG0259	pyridoxamine-phosphate oxidase activity
HQ399_15855	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
HQ399_15855	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
HQ399_15865	COG1882	Formate acetyltransferase
HQ399_15870	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HQ399_15880	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
HQ399_15885	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
HQ399_15900	COG3088	subunit of a heme lyase
HQ399_15900	COG4235	cytochrome complex assembly
HQ399_15910	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
HQ399_15915	COG1138	Cytochrome C-type biogenesis protein
HQ399_15920	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
HQ399_15925	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
HQ399_15930	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
HQ399_15935	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
HQ399_15950	COG0835	chemotaxis
HQ399_15960	COG1192	Involved in chromosome partitioning
HQ399_15965	COG1360	Flagellar Motor Protein
HQ399_15970	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
HQ399_15975	COG2201	protein-glutamate methylesterase activity
HQ399_15980	COG0643	Histidine kinase
HQ399_15980	COG2198	Histidine kinase
HQ399_15980	COG0784	Response regulator, receiver
HQ399_15985	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
HQ399_16010	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
HQ399_16020	COG1684	flagellar biosynthetic protein fliR
HQ399_16075	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
HQ399_16085	COG1677	Flagellar hook-basal body complex protein FliE
HQ399_16095	COG0469	pyruvate kinase activity
HQ399_16100	COG1737	Transcriptional regulator
HQ399_16135	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HQ399_16140	COG2233	PERMEase
HQ399_16155	COG0281	malic enzyme
HQ399_16160	COG0745	RESPONSE REGULATOR receiver
HQ399_16170	COG0437	4 iron, 4 sulfur cluster binding
HQ399_16175	COG3383	formate dehydrogenase (NAD+) activity
HQ399_16175	COG3383	formate dehydrogenase (NAD+) activity
HQ399_16210	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
HQ399_16220	COG3852	Histidine kinase
HQ399_16225	COG2204	response regulator
HQ399_16235	COG4662	Binding-protein-dependent transport system inner membrane component
HQ399_16245	COG0746	molybdenum cofactor guanylyltransferase activity
HQ399_16250	COG0303	'Molybdopterin
HQ399_16255	COG1289	transmembrane transporter activity
HQ399_16260	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
HQ399_16300	COG0784	Response regulator, receiver
HQ399_16300	COG2205	protein histidine kinase activity
HQ399_16305	COG4166	transmembrane transport
HQ399_16310	COG0601	transmembrane transport
HQ399_16315	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
HQ399_16320	COG0444	Belongs to the ABC transporter superfamily
HQ399_16325	COG4608	Belongs to the ABC transporter superfamily
HQ399_16335	COG2971	BadF BadG BcrA BcrD
HQ399_16360	COG3724	N-succinylarginine dihydrolase activity
HQ399_16385	COG0784	Response regulator, receiver
HQ399_16385	COG5002	protein histidine kinase activity
HQ399_16385	COG2205	protein histidine kinase activity
HQ399_16390	COG2197	response regulator
HQ399_16395	COG2199	diguanylate cyclase activity
HQ399_16395	COG2200	EAL domain
HQ399_16395	COG2203	Gaf domain
HQ399_16400	COG0826	peptidase U32
HQ399_16405	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
HQ399_16415	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
HQ399_16420	COG2203	Gaf domain
HQ399_16420	COG2199	diguanylate cyclase activity
HQ399_16425	COG2211	Major facilitator Superfamily
HQ399_16430	COG0616	signal peptide processing
HQ399_16435	COG1028	Short-chain dehydrogenase reductase Sdr
HQ399_16440	COG0583	DNA-binding transcription factor activity
HQ399_16450	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
HQ399_16465	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
HQ399_16470	COG1881	PFAM PEBP family protein
HQ399_16480	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
HQ399_16480	COG3408	Glycogen debranching enzyme
HQ399_16490	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
HQ399_16505	COG1301	dicarboxylic acid transport
HQ399_16510	COG2877	3-deoxy-8-phosphooctulonate synthase activity
HQ399_16515	COG2912	Transglutaminase-like superfamily
HQ399_16525	COG2890	protein-(glutamine-N5) methyltransferase activity
HQ399_16530	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
HQ399_16535	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
HQ399_16540	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
HQ399_16545	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
HQ399_16555	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HQ399_16560	COG0737	Belongs to the 5'-nucleotidase family
HQ399_16565	COG0193	aminoacyl-tRNA hydrolase activity
HQ399_16570	COG0012	GTP binding
HQ399_16575	COG1012	belongs to the aldehyde dehydrogenase family
HQ399_16580	COG1177	transmembrane transport
HQ399_16585	COG1176	ABC-type spermidine putrescine transport system, permease component I
HQ399_16590	COG3842	ATPase activity
HQ399_16595	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
HQ399_16600	COG0583	DNA-binding transcription factor activity
HQ399_16645	COG0471	metal ion transport
HQ399_16645	COG0490	domain, Protein
HQ399_16655	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
HQ399_16670	COG0657	acetylesterase activity
HQ399_16680	COG0366	Alpha amylase catalytic
HQ399_16685	COG0674	pyruvate-flavodoxin oxidoreductase activity
HQ399_16685	COG1013	pyruvate-flavodoxin oxidoreductase activity
HQ399_16685	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
HQ399_16685	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
HQ399_16695	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
HQ399_16710	COG1012	belongs to the aldehyde dehydrogenase family
HQ399_16720	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
HQ399_16725	COG0512	Glutamine amidotransferase of anthranilate synthase
HQ399_16735	COG0180	Tryptophanyl-tRNA synthetase
HQ399_16745	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
HQ399_16750	COG0338	D12 class N6 adenine-specific DNA methyltransferase
HQ399_16760	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
HQ399_16765	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
HQ399_16795	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
HQ399_16800	COG0583	DNA-binding transcription factor activity
HQ399_16820	COG0583	DNA-binding transcription factor activity
HQ399_16830	COG0739	heme binding
HQ399_16840	COG1511	domain protein
HQ399_16840	COG3264	Mechanosensitive ion channel
HQ399_16845	COG0584	glycerophosphoryl diester phosphodiesterase
HQ399_16855	COG1053	succinate dehydrogenase
HQ399_16860	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
HQ399_16865	COG3029	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
HQ399_16875	COG3366	ferrous iron transmembrane transporter activity
HQ399_16880	COG0700	Nucleoside recognition
HQ399_16885	COG2195	Cleaves the N-terminal amino acid of tripeptides
HQ399_16895	COG3214	Protein conserved in bacteria
HQ399_16910	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
HQ399_16925	COG0318	PFAM AMP-dependent synthetase and ligase
HQ399_16935	COG1028	Short-chain dehydrogenase reductase Sdr
HQ399_16960	COG0516	GMP reductase activity
HQ399_16970	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
HQ399_16980	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HQ399_16995	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
HQ399_17005	COG3069	C4-dicarboxylate transmembrane transporter activity
HQ399_17030	COG3706	GGDEF domain
HQ399_17040	COG1335	isochorismatase
HQ399_17045	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
HQ399_17050	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
HQ399_17055	COG1702	phosphate starvation-inducible protein PhoH
HQ399_17060	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
HQ399_17065	COG4535	Mg2 and Co2 transporter CorC
HQ399_17070	COG0815	Transfers the fatty acyl group on membrane lipoproteins
HQ399_17085	COG1970	mechanosensitive ion channel activity
HQ399_17090	COG4974	Belongs to the 'phage' integrase family
HQ399_17095	COG0716	FMN binding
HQ399_17105	COG0312	modulator of DNA gyrase
HQ399_17115	COG2888	peptidyl-tyrosine sulfation
HQ399_17120	COG0495	leucyl-tRNA aminoacylation
HQ399_17135	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
HQ399_17140	COG0799	negative regulation of ribosome biogenesis
HQ399_17145	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
HQ399_17150	COG0768	penicillin binding
HQ399_17155	COG0772	Belongs to the SEDS family
HQ399_17160	COG2951	lytic endotransglycosylase activity
HQ399_17165	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
HQ399_17170	COG1686	Belongs to the peptidase S11 family
HQ399_17175	COG2921	Belongs to the UPF0250 family
HQ399_17180	COG0321	lipoyl(octanoyl) transferase activity
HQ399_17185	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
HQ399_17205	COG3139	Protein of unknown function (DUF1315)
HQ399_17210	COG0252	asparaginase activity
HQ399_17215	COG0786	glutamate:sodium symporter activity
HQ399_17230	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
HQ399_17235	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
HQ399_17240	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
HQ399_17245	COG0175	sulfate reduction
HQ399_17255	COG3610	response to peptide
HQ399_17260	COG2966	Psort location CytoplasmicMembrane, score
HQ399_17270	COG0521	Mo-molybdopterin cofactor biosynthetic process
HQ399_17285	COG2897	thiosulfate sulfurtransferase activity
HQ399_17290	COG2066	Belongs to the glutaminase family
HQ399_17295	COG3171	Protein conserved in bacteria
HQ399_17300	COG0220	tRNA (guanine-N7-)-methyltransferase activity
HQ399_17305	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HQ399_17310	COG2200	EAL domain
HQ399_17315	COG1090	epimerase
HQ399_17320	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
HQ399_17325	COG4181	ATPase activity
HQ399_17330	COG2755	lipolytic protein G-D-S-L family
HQ399_17335	COG0835	chemotaxis
HQ399_17335	COG0784	Response regulator, receiver
HQ399_17375	COG3397	chitin binding
HQ399_17390	COG0784	Response regulator, receiver
HQ399_17390	COG5002	protein histidine kinase activity
HQ399_17390	COG2205	protein histidine kinase activity
HQ399_17395	COG2814	Major facilitator Superfamily
HQ399_17415	COG3501	Rhs element vgr protein
HQ399_17425	COG2771	luxR family
HQ399_17450	COG0748	coenzyme F420 binding
HQ399_17455	COG3721	Heme iron utilization protein
HQ399_17465	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HQ399_17485	COG3279	Response regulator of the LytR AlgR family
HQ399_17490	COG1966	Carbon starvation protein
HQ399_17505	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HQ399_17525	COG0737	Belongs to the 5'-nucleotidase family
HQ399_17545	COG2204	response regulator
HQ399_17550	COG0545	Peptidyl-prolyl cis-trans isomerase
HQ399_17565	COG1047	Peptidyl-prolyl cis-trans
HQ399_17570	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
HQ399_17580	COG0835	chemotaxis
HQ399_17580	COG0784	Response regulator, receiver
HQ399_17585	COG0429	hydrolase of the alpha beta-hydrolase fold
HQ399_17590	COG2203	Gaf domain
HQ399_17590	COG4251	negative regulation of phosphorylation
HQ399_17590	COG5001	Diguanylate cyclase
HQ399_17590	COG3706	GGDEF domain
HQ399_17595	COG3089	Belongs to the UPF0270 family
HQ399_17600	COG3954	Phosphoribulokinase
HQ399_17615	COG1765	OsmC-like protein
HQ399_17655	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HQ399_17660	COG2313	pseudouridylate synthase activity
HQ399_17695	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
HQ399_17710	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
HQ399_17720	COG2986	histidine ammonia-lyase
HQ399_17745	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
HQ399_17750	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
HQ399_17755	COG1028	Short-chain dehydrogenase reductase Sdr
HQ399_17760	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
HQ399_17780	COG3076	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome
HQ399_17860	COG2985	domain, Protein
HQ399_17860	COG0569	domain protein
HQ399_17865	COG1272	protein, Hemolysin III
HQ399_17870	COG0076	glutamate decarboxylase activity
HQ399_17875	COG2917	probably involved in intracellular septation
HQ399_17880	COG2350	Protein conserved in bacteria
HQ399_17890	COG1349	DNA-binding transcription factor activity
HQ399_17900	COG2222	sugar isomerase
HQ399_17905	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HQ399_17915	COG3716	PTS system mannose fructose sorbose family IID component
HQ399_17920	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
HQ399_17925	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
HQ399_17935	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HQ399_17935	COG1263	PTS System
HQ399_17940	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
HQ399_17945	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
HQ399_17950	COG1381	Involved in DNA repair and RecF pathway recombination
HQ399_17965	COG0681	Belongs to the peptidase S26 family
HQ399_17970	COG0481	GTPase activity
HQ399_17980	COG3026	antisigma factor binding
HQ399_17985	COG3073	An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E
HQ399_17990	COG1595	DNA-templated transcription, initiation
HQ399_17995	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
HQ399_18010	COG0354	folic acid binding
HQ399_18055	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
HQ399_18065	COG0126	phosphoglycerate kinase activity
HQ399_18070	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
HQ399_18075	COG1940	carbohydrate kinase activity
HQ399_18080	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
HQ399_18085	COG2816	NAD+ diphosphatase activity
HQ399_18090	COG0506	proline dehydrogenase activity
HQ399_18090	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
HQ399_18090	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
HQ399_18095	COG4991	sh3 domain protein
HQ399_18100	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
HQ399_18115	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
HQ399_18140	COG2205	protein histidine kinase activity
HQ399_18190	COG1912	Pfam S-adenosyl-l-methionine hydroxide adenosyltransferase
HQ399_18200	COG2203	Gaf domain
HQ399_18200	COG2199	diguanylate cyclase activity
HQ399_18205	COG0513	Belongs to the DEAD box helicase family
HQ399_18215	COG0471	metal ion transport
HQ399_18230	COG0154	amidase activity
HQ399_18235	COG2957	Belongs to the agmatine deiminase family
HQ399_18245	COG2852	Protein conserved in bacteria
HQ399_18255	COG1902	pentaerythritol trinitrate reductase activity
HQ399_18265	COG1388	LysM domain
HQ399_18265	COG4942	peptidase
HQ399_18270	COG1238	metal cluster binding
HQ399_18275	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
HQ399_18280	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
HQ399_18285	COG0585	pseudouridine synthase activity
HQ399_18295	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
HQ399_18300	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
HQ399_18305	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HQ399_18315	COG1376	ErfK ybiS ycfS ynhG family protein
HQ399_18320	COG0668	transmembrane transport
HQ399_18330	COG2731	YhcH YjgK YiaL family protein
HQ399_18340	COG1794	racemase activity, acting on amino acids and derivatives
HQ399_18355	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HQ399_18375	COG0488	(ABC) transporter
HQ399_18385	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
HQ399_18395	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
HQ399_18410	COG0148	phosphopyruvate hydratase activity
HQ399_18415	COG0504	CTP synthase activity
HQ399_18420	COG3956	TIGRFAM MazG family protein
HQ399_18425	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HQ399_18430	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HQ399_18440	COG4807	Protein conserved in bacteria
HQ399_18445	COG3023	N-Acetylmuramoyl-L-alanine amidase
HQ399_18450	COG0783	Belongs to the Dps family
HQ399_18455	COG1151	hydroxylamine reductase activity
HQ399_18460	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
HQ399_18465	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
HQ399_18470	COG0671	phosphoesterase, PA-phosphatase related
HQ399_18475	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
HQ399_18480	COG0163	prenyltransferase activity
HQ399_18495	COG1131	(ABC) transporter
HQ399_18500	COG0842	Transport permease protein
HQ399_18505	COG1775	2-hydroxyglutaryl-CoA dehydratase, D-component
HQ399_18510	COG1924	4 iron, 4 sulfur cluster binding
HQ399_18530	COG1823	symporter activity
HQ399_18540	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
HQ399_18545	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
HQ399_18550	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
HQ399_18560	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
HQ399_18565	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
HQ399_18570	COG1489	DNA binding
HQ399_18580	COG1643	Atp-dependent helicase
HQ399_18585	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
HQ399_18590	COG0346	lactoylglutathione lyase activity
HQ399_18595	COG2076	Multidrug Resistance protein
HQ399_18600	COG2076	Multidrug Resistance protein
HQ399_18610	COG3437	response regulator, receiver
HQ399_18610	COG0784	Response regulator, receiver
HQ399_18615	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
HQ399_18630	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
HQ399_18645	COG1136	(ABC) transporter
HQ399_18665	COG0840	transmembrane signaling receptor activity
HQ399_18680	COG0529	Catalyzes the synthesis of activated sulfate
HQ399_18685	COG2895	sulfate adenylyltransferase (ATP) activity
HQ399_18690	COG0175	sulfate reduction
HQ399_18695	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
HQ399_18695	COG1648	precorrin-2 dehydrogenase activity
HQ399_18700	COG0330	HflC and HflK could
HQ399_18705	COG1585	Membrane protein implicated in regulation of membrane protease activity
HQ399_18710	COG0840	transmembrane signaling receptor activity
HQ399_18715	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
HQ399_18725	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
HQ399_18730	COG1640	4-alpha-glucanotransferase
HQ399_18735	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
HQ399_18755	COG1051	belongs to the nudix hydrolase family
HQ399_18780	COG0561	phosphatase activity
HQ399_18795	COG0733	neurotransmitter:sodium symporter activity
HQ399_18805	COG0733	neurotransmitter:sodium symporter activity
HQ399_18870	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
HQ399_18875	COG2885	chlorophyll binding
HQ399_18880	COG0823	Involved in the tonB-independent uptake of proteins
HQ399_18895	COG0811	peptide transport
HQ399_18900	COG0824	Thioesterase
HQ399_18905	COG3790	cyd operon protein YbgE
HQ399_18910	COG4890	Cyd operon protein YbgT
HQ399_18915	COG1294	oxidase, subunit
HQ399_18925	COG2255	four-way junction helicase activity
HQ399_18930	COG0632	four-way junction helicase activity
HQ399_18935	COG0840	transmembrane signaling receptor activity
HQ399_18945	COG2771	luxR family
HQ399_18960	COG4776	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction
HQ399_18965	COG3706	GGDEF domain
HQ399_18965	COG4251	negative regulation of phosphorylation
HQ399_18965	COG5001	Diguanylate cyclase
HQ399_18965	COG2203	Gaf domain
HQ399_18975	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
HQ399_18985	COG2995	paraquat-inducible protein a
HQ399_18990	COG3008	intermembrane lipid transfer
HQ399_18990	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
HQ399_18995	COG3009	Protein conserved in bacteria
HQ399_19000	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HQ399_19005	COG0442	prolyl-tRNA aminoacylation
HQ399_19010	COG4221	oxidoreductase activity
HQ399_19025	COG1024	Enoyl-CoA hydratase
HQ399_19035	COG0110	maltose O-acetyltransferase activity
HQ399_19045	COG4166	transmembrane transport
HQ399_19055	COG0840	transmembrane signaling receptor activity
HQ399_19060	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HQ399_19065	COG0735	belongs to the Fur family
HQ399_19095	COG0513	Belongs to the DEAD box helicase family
HQ399_19100	COG2153	protein acetylation
HQ399_19110	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HQ399_19115	COG0557	exoribonuclease II activity
HQ399_19120	COG3706	GGDEF domain
HQ399_19130	COG3240	lipase activity
HQ399_19145	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
HQ399_19150	COG1194	a g-specific adenine glycosylase
HQ399_19155	COG0617	tRNA 3'-terminal CCA addition
HQ399_19175	COG3068	Protein conserved in bacteria
HQ399_19185	COG0739	heme binding
HQ399_19205	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
HQ399_19210	COG1121	(ABC) transporter
HQ399_19215	COG1108	ABC-type Mn2 Zn2 transport systems permease components
HQ399_19220	COG0583	DNA-binding transcription factor activity
HQ399_19225	COG0697	spore germination
HQ399_19230	COG1573	uracil-dna glycosylase
HQ399_19245	COG2827	Endonuclease containing a URI domain
HQ399_19260	COG1842	Phage shock protein A
HQ399_19265	COG0204	Acyl-transferase
HQ399_19285	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
HQ399_19290	COG0583	DNA-binding transcription factor activity
HQ399_19295	COG2084	Dehydrogenase
HQ399_19325	COG3104	oligopeptide transport
HQ399_19345	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
HQ399_19365	COG2329	Antibiotic biosynthesis monooxygenase
HQ399_19370	COG0187	DNA topoisomerase II activity
HQ399_19375	COG1289	transmembrane transporter activity
HQ399_19380	COG1566	PFAM secretion protein HlyD family protein
HQ399_19395	COG1051	belongs to the nudix hydrolase family
HQ399_19400	COG3150	esterase
HQ399_19410	COG3151	Protein conserved in bacteria
HQ399_19415	COG0494	nUDIX hydrolase
HQ399_19420	COG1538	Outer membrane efflux protein
HQ399_19425	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
HQ399_19425	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
HQ399_19430	COG1560	Kdo2-lipid A biosynthetic process
HQ399_19435	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
HQ399_19435	COG2213	PTS system mannitol-specific
HQ399_19440	COG0246	Mannitol dehydrogenase
HQ399_19445	COG3722	fumarate hydratase activity
HQ399_19470	COG1671	Belongs to the UPF0178 family
HQ399_19485	COG1988	membrane-bound metal-dependent
HQ399_19490	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
HQ399_19495	COG0513	Belongs to the DEAD box helicase family
HQ399_19515	COG1575	Belongs to the MenA family. Type 1 subfamily
HQ399_19520	COG1169	isochorismate synthase
HQ399_19525	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
HQ399_19530	COG0596	Alpha beta hydrolase
HQ399_19535	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
HQ399_19545	COG0318	PFAM AMP-dependent synthetase and ligase
HQ399_19550	COG3291	Pkd domain containing protein
HQ399_19555	COG2949	membrane
HQ399_19560	COG0784	Response regulator, receiver
HQ399_19560	COG0835	chemotaxis
HQ399_19570	COG1444	tRNA N-acetyltransferase activity
HQ399_19590	COG1803	Methylglyoxal synthase
HQ399_19595	COG1979	alcohol dehydrogenase
HQ399_19610	COG4221	oxidoreductase activity
HQ399_19630	COG1285	pathogenesis
HQ399_19650	COG1368	sulfuric ester hydrolase activity
HQ399_19655	COG1522	sequence-specific DNA binding
HQ399_19665	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
HQ399_19670	COG1418	mRNA catabolic process
HQ399_19675	COG1546	Belongs to the CinA family
HQ399_19675	COG1058	Belongs to the CinA family
HQ399_19685	COG0561	phosphatase activity
HQ399_19695	COG2926	Belongs to the UPF0265 family
HQ399_19725	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
HQ399_19730	COG0564	pseudouridine synthase activity
HQ399_19740	COG0110	maltose O-acetyltransferase activity
HQ399_19745	COG0366	Alpha amylase catalytic
HQ399_19750	COG1263	PTS System
HQ399_19750	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HQ399_19770	COG0252	asparaginase activity
HQ399_19775	COG1253	flavin adenine dinucleotide binding
HQ399_19780	COG0586	Pfam SNARE associated Golgi protein
HQ399_19785	COG1686	Belongs to the peptidase S11 family
HQ399_19825	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
HQ399_19835	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
HQ399_19845	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
HQ399_19850	COG1546	Belongs to the CinA family
HQ399_19855	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
HQ399_19860	COG4667	esterase of the alpha-beta hydrolase superfamily
HQ399_19870	COG1346	cytolysis
HQ399_19875	COG1380	Effector of murein hydrolase LrgA
HQ399_19895	COG0583	DNA-binding transcription factor activity
HQ399_19925	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
HQ399_19935	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
HQ399_19940	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
HQ399_19950	COG0137	argininosuccinate synthase activity
HQ399_19955	COG0165	Argininosuccinate lyase
HQ399_19970	COG3314	Sporulation integral membrane protein YlbJ
HQ399_19995	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
HQ399_20000	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
HQ399_20010	COG0477	Major facilitator Superfamily
HQ399_20015	COG0523	cobalamin synthesis protein
HQ399_20025	COG2200	EAL domain
HQ399_20030	COG1049	propionate catabolic process, 2-methylcitrate cycle
HQ399_20035	COG1752	Esterase of the alpha-beta hydrolase superfamily
HQ399_20040	COG0840	transmembrane signaling receptor activity
HQ399_20045	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
HQ399_20050	COG0508	dehydrogenase complex catalyzes the overall conversion of
HQ399_20055	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
HQ399_20060	COG2186	Transcriptional regulator
HQ399_20085	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
HQ399_20090	COG1459	type II secretion system
HQ399_20105	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
HQ399_20110	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
HQ399_20115	COG0494	nUDIX hydrolase
HQ399_20120	COG0653	protein targeting
HQ399_20130	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
HQ399_20135	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
HQ399_20140	COG0849	cell division
HQ399_20150	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
HQ399_20155	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
HQ399_20160	COG0772	Belongs to the SEDS family
HQ399_20165	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
HQ399_20170	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
HQ399_20175	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
HQ399_20180	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
HQ399_20185	COG0768	penicillin binding
HQ399_20190	COG3116	cell division
HQ399_20195	COG0275	rRNA processing
HQ399_20200	COG2001	Belongs to the MraZ family
HQ399_20210	COG0741	lytic transglycosylase activity
HQ399_20210	COG1388	LysM domain
HQ399_20215	COG1360	Flagellar Motor Protein
HQ399_20220	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
HQ399_20225	COG1191	sigma factor activity
HQ399_20250	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
HQ399_20255	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
HQ399_20270	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
HQ399_20275	COG4786	Flagellar basal body rod
HQ399_20275	COG1256	bacterial-type flagellum assembly
HQ399_20285	COG1706	bacterial-type flagellum-dependent cell motility
HQ399_20290	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
HQ399_20295	COG4786	Flagellar basal body rod
HQ399_20320	COG1815	bacterial-type flagellum-dependent cell motility
HQ399_20330	COG2747	anti-sigma28 factor FlgM
HQ399_20355	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
HQ399_20365	COG1677	Flagellar hook-basal body complex protein FliE
HQ399_20415	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
HQ399_20420	COG3107	peptidoglycan biosynthetic process
HQ399_20425	COG0792	nuclease activity
HQ399_20430	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
HQ399_20440	COG2969	positive regulation of protein catabolic process
HQ399_20445	COG0625	glutathione transferase activity
HQ399_20450	COG2857	Cytochrome c1
HQ399_20455	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
HQ399_20460	COG0723	plastoquinol--plastocyanin reductase activity
HQ399_20465	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
HQ399_20470	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
HQ399_20475	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
HQ399_20485	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HQ399_20490	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HQ399_20520	COG3964	amidohydrolase
HQ399_20535	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
HQ399_20535	COG3711	transcriptional antiterminator
HQ399_20540	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
HQ399_20545	COG1660	Displays ATPase and GTPase activities
HQ399_20550	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
HQ399_20560	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
HQ399_20565	COG1137	ATPase activity
HQ399_20570	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
HQ399_20580	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
HQ399_20585	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
HQ399_20585	COG0517	IMP dehydrogenase activity
HQ399_20590	COG1127	ABC transporter
HQ399_20595	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
HQ399_20600	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
HQ399_20605	COG2854	intermembrane phospholipid transfer
HQ399_20615	COG5007	Belongs to the BolA IbaG family
HQ399_20620	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HQ399_20625	COG0312	modulator of DNA gyrase
HQ399_20630	COG3028	Belongs to the UPF0307 family
HQ399_20640	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
HQ399_20650	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
HQ399_20655	COG1011	Hydrolase
HQ399_20670	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
HQ399_20675	COG0019	diaminopimelate decarboxylase activity
HQ399_20685	COG1965	Belongs to the frataxin family
HQ399_20690	COG0400	carboxylic ester hydrolase activity
HQ399_20695	COG3072	Adenylate cyclase
HQ399_20700	COG0181	hydroxymethylbilane synthase activity
HQ399_20710	COG2959	enzyme of heme biosynthesis
HQ399_20725	COG1494	fructose-1,6-bisphosphatase
HQ399_20750	COG1686	Belongs to the peptidase S11 family
HQ399_20780	COG0795	lipopolysaccharide-transporting ATPase activity
HQ399_20785	COG0795	lipopolysaccharide-transporting ATPase activity
HQ399_20790	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
HQ399_20795	COG2927	DNA polymerase III (CHI subunit)
HQ399_20820	COG0456	acetyltransferase
HQ399_20820	COG0454	-acetyltransferase
HQ399_20825	COG0456	acetyltransferase
HQ399_20825	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
HQ399_20850	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
HQ399_20855	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
HQ399_20860	COG5380	lipid catabolic process
HQ399_20885	COG2873	o-acetylhomoserine
HQ399_20915	COG3842	ATPase activity
HQ399_20925	COG1175	transmembrane transport
HQ399_20950	COG3069	C4-dicarboxylate transmembrane transporter activity
HQ399_20965	COG2199	diguanylate cyclase activity
HQ399_20965	COG2203	Gaf domain
HQ399_20980	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
HQ399_20985	COG1074	ATP-dependent DNA helicase activity
HQ399_20995	COG2259	Doxx family
HQ399_21000	COG1741	Belongs to the pirin family
HQ399_21010	COG0583	DNA-binding transcription factor activity
HQ399_21030	COG3706	GGDEF domain
HQ399_21035	COG4771	TonB-dependent receptor
HQ399_21070	COG0203	ribosomal protein L17
HQ399_21075	COG0202	RNA polymerase activity
HQ399_21080	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
HQ399_21085	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
HQ399_21090	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
HQ399_21095	COG0257	Belongs to the bacterial ribosomal protein bL36 family
HQ399_21100	COG0201	protein transport
HQ399_21105	COG0200	Binds to the 23S rRNA
HQ399_21110	COG1841	ribosomal large subunit assembly
HQ399_21115	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
HQ399_21120	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
HQ399_21125	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
HQ399_21130	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit