locus-tag	class	description
NRZ30_00010	COG4695	Portal protein
NRZ30_00105	COG4974	Belongs to the 'phage' integrase family
NRZ30_00140	COG0642	Histidine kinase
NRZ30_00145	COG2261	transglycosylase associated protein
NRZ30_00155	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
NRZ30_00165	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
NRZ30_00170	COG0215	cysteine-tRNA ligase activity
NRZ30_00215	COG2119	membrane
NRZ30_00220	COG0023	Translation Initiation Factor
NRZ30_00230	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
NRZ30_00245	COG0513	Belongs to the DEAD box helicase family
NRZ30_00260	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
NRZ30_00265	COG0765	amino acid transport
NRZ30_00270	COG1126	abc transporter atp-binding protein
NRZ30_00275	COG0493	'glutamate synthase
NRZ30_00280	COG0069	glutamate synthase activity
NRZ30_00280	COG0070	glutamate synthase
NRZ30_00280	COG0067	glutamate synthase
NRZ30_00285	COG1242	4 iron, 4 sulfur cluster binding
NRZ30_00335	COG3634	alkyl hydroperoxide reductase activity
NRZ30_00345	COG1125	glycine betaine transport
NRZ30_00345	COG0517	IMP dehydrogenase activity
NRZ30_00350	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
NRZ30_00355	COG0343	queuine tRNA-ribosyltransferase activity
NRZ30_00360	COG1862	Preprotein translocase
NRZ30_00365	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
NRZ30_00370	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
NRZ30_00385	COG0826	peptidase U32
NRZ30_00390	COG0826	peptidase U32
NRZ30_00395	COG3154	lipid carrier protein
NRZ30_00410	COG1959	2 iron, 2 sulfur cluster binding
NRZ30_00415	COG1104	cysteine desulfurase activity
NRZ30_00420	COG0822	iron-sulfur transferase activity
NRZ30_00430	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
NRZ30_00435	COG0443	Heat shock 70 kDa protein
NRZ30_00440	COG0633	Ferredoxin
NRZ30_00445	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
NRZ30_00450	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
NRZ30_00455	COG0105	UTP biosynthetic process
NRZ30_00460	COG0820	rRNA (adenine-C2-)-methyltransferase activity
NRZ30_00480	COG0124	histidyl-tRNA synthetase
NRZ30_00485	COG2976	Protein conserved in bacteria
NRZ30_00490	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
NRZ30_00495	COG1160	GTP binding
NRZ30_00500	COG1645	bacterial-type flagellum-dependent swarming motility
NRZ30_00505	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
NRZ30_00510	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
NRZ30_00510	COG0047	phosphoribosylformylglycinamidine synthase activity
NRZ30_00515	COG1007	ATP synthesis coupled electron transport
NRZ30_00520	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
NRZ30_00530	COG0713	ATP synthesis coupled electron transport
NRZ30_00535	COG0839	Belongs to the complex I subunit 6 family
NRZ30_00540	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
NRZ30_00545	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
NRZ30_00550	COG1034	ATP synthesis coupled electron transport
NRZ30_00565	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
NRZ30_00565	COG0649	NAD binding
NRZ30_00570	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
NRZ30_00575	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
NRZ30_00580	COG1360	Flagellar Motor Protein
NRZ30_00585	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
NRZ30_00600	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
NRZ30_00610	COG3770	Murein endopeptidase that cleaves the D-alanyl-meso-2,6- diamino-pimelyl amide bond that connects peptidoglycan strands. Likely plays a role in the removal of murein from the sacculus
NRZ30_00615	COG4597	amino acid ABC transporter
NRZ30_00625	COG0765	amino acid transport
NRZ30_00640	COG0724	RNA recognition motif
NRZ30_00645	COG4989	oxidoreductase activity
NRZ30_00670	COG3437	response regulator, receiver
NRZ30_00675	COG0583	DNA-binding transcription factor activity
NRZ30_00680	COG3300	MHYT domain
NRZ30_00680	COG5001	Diguanylate cyclase
NRZ30_00685	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
NRZ30_00690	COG0778	Nitroreductase
NRZ30_00705	COG2814	Major facilitator Superfamily
NRZ30_00710	COG0583	DNA-binding transcription factor activity
NRZ30_00715	COG0583	DNA-binding transcription factor activity
NRZ30_00720	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
NRZ30_00725	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
NRZ30_00730	COG0539	negative regulation of cytoplasmic translation
NRZ30_00735	COG0776	regulation of translation
NRZ30_00745	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
NRZ30_00765	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
NRZ30_00770	COG0602	queuosine metabolic process
NRZ30_00775	COG3530	Putative quorum-sensing-regulated virulence factor
NRZ30_00780	COG2096	Adenosyltransferase
NRZ30_00785	COG2916	Histone family protein nucleoid-structuring protein H-NS
NRZ30_00790	COG1757	Na H antiporter
NRZ30_00795	COG1435	thymidine kinase activity
NRZ30_00835	COG0659	secondary active sulfate transmembrane transporter activity
NRZ30_00910	COG3829	transcription factor binding
NRZ30_00945	COG4104	PAAR repeat-containing protein
NRZ30_00960	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
NRZ30_00965	COG0326	Molecular chaperone. Has ATPase activity
NRZ30_00970	COG4172	Belongs to the ABC transporter superfamily
NRZ30_00995	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
NRZ30_01000	COG1842	Phage shock protein A
NRZ30_01015	COG3106	COG3106 Predicted ATPase
NRZ30_01020	COG3768	UPF0283 membrane protein
NRZ30_01030	COG2154	pterin-4-alpha-carbinolamine dehydratase
NRZ30_01050	COG2199	diguanylate cyclase activity
NRZ30_01055	COG2885	chlorophyll binding
NRZ30_01060	COG0861	Integral membrane protein TerC family
NRZ30_01075	COG1022	Amp-dependent synthetase and ligase
NRZ30_01090	COG2910	NAD(P)H-binding
NRZ30_01095	COG0583	DNA-binding transcription factor activity
NRZ30_01100	COG2271	Major facilitator Superfamily
NRZ30_01110	COG1335	isochorismatase
NRZ30_01125	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
NRZ30_01140	COG0583	DNA-binding transcription factor activity
NRZ30_01145	COG2723	6-phospho-beta-galactosidase activity
NRZ30_01150	COG1944	ATP diphosphatase activity
NRZ30_01155	COG2116	formate transmembrane transporter activity
NRZ30_01160	COG1882	Formate acetyltransferase
NRZ30_01165	COG2983	Belongs to the UPF0260 family
NRZ30_01180	COG0058	SHG alpha-glucan phosphorylase activity
NRZ30_01185	COG0471	metal ion transport
NRZ30_01190	COG3118	belongs to the thioredoxin family
NRZ30_01195	COG2205	protein histidine kinase activity
NRZ30_01195	COG3850	Histidine kinase
NRZ30_01195	COG4999	Histidine kinase
NRZ30_01195	COG3437	response regulator, receiver
NRZ30_01200	COG1132	(ABC) transporter
NRZ30_01205	COG1132	(ABC) transporter
NRZ30_01215	COG2501	S4 domain
NRZ30_01230	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
NRZ30_01280	COG2009	succinate dehydrogenase
NRZ30_01285	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
NRZ30_01290	COG1053	succinate dehydrogenase
NRZ30_01300	COG0567	Dehydrogenase, E1 component
NRZ30_01305	COG0508	dehydrogenase complex catalyzes the overall conversion of
NRZ30_01310	COG0045	succinate-CoA ligase (ADP-forming) activity
NRZ30_01340	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
NRZ30_01350	COG3842	ATPase activity
NRZ30_01360	COG1840	ABC-type Fe3 transport system, periplasmic component
NRZ30_01370	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
NRZ30_01380	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
NRZ30_01385	COG3088	subunit of a heme lyase
NRZ30_01385	COG4235	cytochrome complex assembly
NRZ30_01390	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
NRZ30_01395	COG1138	Cytochrome C-type biogenesis protein
NRZ30_01400	COG3301	Polysulphide reductase, NrfD
NRZ30_01405	COG0437	4 iron, 4 sulfur cluster binding
NRZ30_01410	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
NRZ30_01425	COG0247	lactate metabolic process
NRZ30_01430	COG3075	Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses fumarate or nitrate as electron acceptor
NRZ30_01435	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
NRZ30_01450	COG0840	transmembrane signaling receptor activity
NRZ30_01455	COG1940	carbohydrate kinase activity
NRZ30_01455	COG1846	Transcriptional regulator
NRZ30_01460	COG3148	PFAM DTW domain containing protein
NRZ30_01465	COG0730	response to heat
NRZ30_01470	COG0583	DNA-binding transcription factor activity
NRZ30_01490	COG3593	DNA synthesis involved in DNA repair
NRZ30_01545	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
NRZ30_01550	COG1011	Hydrolase
NRZ30_01565	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
NRZ30_01570	COG2832	Protein of unknown function (DUF454)
NRZ30_01575	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
NRZ30_01585	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
NRZ30_01600	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
NRZ30_01605	COG0583	DNA-binding transcription factor activity
NRZ30_01615	COG1560	Kdo2-lipid A biosynthetic process
NRZ30_01620	COG1560	Kdo2-lipid A biosynthetic process
NRZ30_01640	COG0417	DNA replication proofreading
NRZ30_01655	COG1451	nucleotide metabolic process
NRZ30_01670	COG3069	C4-dicarboxylate transmembrane transporter activity
NRZ30_01685	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
NRZ30_01685	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
NRZ30_01690	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
NRZ30_01695	COG0569	domain protein
NRZ30_01695	COG2985	domain, Protein
NRZ30_01705	COG0556	nucleotide-excision repair
NRZ30_01715	COG0586	Pfam SNARE associated Golgi protein
NRZ30_01720	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
NRZ30_01725	COG3067	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
NRZ30_01750	COG3829	transcription factor binding
NRZ30_01780	COG0534	Mate efflux family protein
NRZ30_01795	COG0307	riboflavin synthase, alpha
NRZ30_01810	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
NRZ30_01815	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
NRZ30_01820	COG0697	spore germination
NRZ30_01825	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
NRZ30_01865	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
NRZ30_01870	COG3099	Belongs to the UPF0263 family
NRZ30_01875	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
NRZ30_01880	COG2894	cell division
NRZ30_01885	COG0850	regulation of cytokinetic process
NRZ30_01890	COG3100	YcgL domain-containing protein
NRZ30_01895	COG2824	Alkylphosphonate utilization operon protein PhnA
NRZ30_01910	COG3791	Glutathione-dependent formaldehyde-activating
NRZ30_01920	COG3706	GGDEF domain
NRZ30_01925	COG2840	Smr protein MutS2
NRZ30_01930	COG2890	protein-(glutamine-N5) methyltransferase activity
NRZ30_01935	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
NRZ30_01945	COG0513	Belongs to the DEAD box helicase family
NRZ30_01950	COG3788	relative of glutathione S-transferase, MAPEG superfamily
NRZ30_01970	COG0814	amino acid
NRZ30_01975	COG1609	Transcriptional regulator
NRZ30_01980	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
NRZ30_01980	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
NRZ30_01985	COG1105	Belongs to the carbohydrate kinase PfkB family
NRZ30_01990	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
NRZ30_01990	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
NRZ30_01990	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
NRZ30_01995	COG3313	Fe-S protein
NRZ30_02000	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
NRZ30_02005	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
NRZ30_02010	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NRZ30_02015	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NRZ30_02025	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
NRZ30_02035	COG0366	Alpha amylase catalytic
NRZ30_02055	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
NRZ30_02060	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
NRZ30_02065	COG0291	Belongs to the bacterial ribosomal protein bL35 family
NRZ30_02070	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
NRZ30_02075	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
NRZ30_02080	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
NRZ30_02085	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NRZ30_02085	COG0072	phenylalanine-tRNA ligase activity
NRZ30_02090	COG0776	regulation of translation
NRZ30_02095	COG2205	protein histidine kinase activity
NRZ30_02095	COG0784	Response regulator, receiver
NRZ30_02115	COG1609	Transcriptional regulator
NRZ30_02120	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
NRZ30_02125	COG1879	ABC-type sugar transport system periplasmic component
NRZ30_02130	COG1172	Belongs to the binding-protein-dependent transport system permease family
NRZ30_02135	COG1129	ABC transporter
NRZ30_02140	COG1869	D-ribose catabolic process
NRZ30_02145	COG0625	glutathione transferase activity
NRZ30_02155	COG1177	transmembrane transport
NRZ30_02180	COG0037	tRNA processing
NRZ30_02185	COG0589	response to stress
NRZ30_02190	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
NRZ30_02215	COG2010	Cytochrome c
NRZ30_02230	COG3278	Belongs to the heme-copper respiratory oxidase family
NRZ30_02245	COG1956	GAF domain-containing protein
NRZ30_02250	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
NRZ30_02260	COG0308	aminopeptidase N
NRZ30_02270	COG2902	Dehydrogenase
NRZ30_02275	COG0167	dihydroorotate dehydrogenase activity
NRZ30_02290	COG4251	negative regulation of phosphorylation
NRZ30_02290	COG3706	GGDEF domain
NRZ30_02290	COG2203	Gaf domain
NRZ30_02290	COG5001	Diguanylate cyclase
NRZ30_02295	COG2201	protein-glutamate methylesterase activity
NRZ30_02305	COG0835	chemotaxis
NRZ30_02310	COG0840	transmembrane signaling receptor activity
NRZ30_02310	COG3290	protein histidine kinase activity
NRZ30_02330	COG0116	Belongs to the methyltransferase superfamily
NRZ30_02330	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
NRZ30_02340	COG0488	(ABC) transporter
NRZ30_02350	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
NRZ30_02355	COG1067	ATP-dependent peptidase activity
NRZ30_02395	COG4128	Pfam Zonular occludens toxin
NRZ30_02445	COG3141	response to X-ray
NRZ30_02455	COG4221	oxidoreductase activity
NRZ30_02480	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
NRZ30_02500	COG0372	Belongs to the citrate synthase family
NRZ30_02505	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
NRZ30_02515	COG2995	paraquat-inducible protein a
NRZ30_02520	COG3008	intermembrane lipid transfer
NRZ30_02525	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
NRZ30_02525	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
NRZ30_02540	COG0084	hydrolase, TatD family'
NRZ30_02545	COG0470	DNA polymerase III
NRZ30_02550	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
NRZ30_02555	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
NRZ30_02560	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
NRZ30_02570	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
NRZ30_02575	COG1028	Short-chain dehydrogenase reductase Sdr
NRZ30_02585	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
NRZ30_02590	COG0416	fatty acid biosynthetic process
NRZ30_02595	COG0333	Belongs to the bacterial ribosomal protein bL32 family
NRZ30_02600	COG1399	metal-binding, possibly nucleic acid-binding protein
NRZ30_02605	COG0424	maF-like protein
NRZ30_02620	COG1530	ribonuclease E activity
NRZ30_02630	COG0306	phosphate transporter
NRZ30_02635	COG0717	Belongs to the dCTP deaminase family
NRZ30_02640	COG0572	uridine kinase
NRZ30_02645	COG0489	protein tyrosine kinase activity
NRZ30_02650	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NRZ30_02650	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NRZ30_02660	COG1254	Belongs to the acylphosphatase family
NRZ30_02665	COG0840	transmembrane signaling receptor activity
NRZ30_02670	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
NRZ30_02680	COG0709	Synthesizes selenophosphate from selenide and ATP
NRZ30_02685	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
NRZ30_02690	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
NRZ30_02700	COG0318	PFAM AMP-dependent synthetase and ligase
NRZ30_02705	COG2267	carboxylic ester hydrolase activity
NRZ30_02715	COG1214	PFAM Peptidase M22, glycoprotease
NRZ30_02720	COG1199	ATP-dependent helicase activity
NRZ30_02730	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
NRZ30_02735	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
NRZ30_02740	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
NRZ30_02745	COG0131	Imidazoleglycerol-phosphate dehydratase
NRZ30_02745	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
NRZ30_02750	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
NRZ30_02755	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
NRZ30_02760	COG0107	imidazoleglycerol-phosphate synthase activity
NRZ30_02775	COG2199	diguanylate cyclase activity
NRZ30_02780	COG0318	PFAM AMP-dependent synthetase and ligase
NRZ30_02785	COG1288	antiporter activity
NRZ30_02795	COG3134	Outer membrane lipoprotein
NRZ30_02800	COG2080	2 iron, 2 sulfur cluster binding
NRZ30_02805	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
NRZ30_02810	COG1529	Aldehyde oxidase and xanthine dehydrogenase
NRZ30_02815	COG2252	PERMEase
NRZ30_02820	COG0402	S-adenosylhomocysteine deaminase activity
NRZ30_02825	COG2233	PERMEase
NRZ30_02830	COG1529	Aldehyde oxidase and xanthine dehydrogenase
NRZ30_02830	COG2080	2 iron, 2 sulfur cluster binding
NRZ30_02835	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
NRZ30_02840	COG0402	S-adenosylhomocysteine deaminase activity
NRZ30_02845	COG0493	'glutamate synthase
NRZ30_02845	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
NRZ30_02855	COG2068	MobA-Related Protein
NRZ30_02860	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
NRZ30_02865	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
NRZ30_02865	COG3608	succinylglutamate desuccinylase aspartoacylase
NRZ30_02870	COG0697	spore germination
NRZ30_02875	COG0549	Belongs to the carbamate kinase family
NRZ30_02885	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
NRZ30_02890	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
NRZ30_02895	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
NRZ30_02925	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
NRZ30_02930	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
NRZ30_02940	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
NRZ30_02945	COG1434	Gram-negative-bacterium-type cell wall biogenesis
NRZ30_02955	COG0205	6-phosphofructokinase activity
NRZ30_02960	COG1301	dicarboxylic acid transport
NRZ30_02965	COG3123	guanosine phosphorylase activity
NRZ30_02970	COG1760	l-serine dehydratase
NRZ30_02975	COG1760	l-serine dehydratase
NRZ30_02995	COG0814	amino acid
NRZ30_03000	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
NRZ30_03005	COG0514	ATP-dependent DNA helicase (RecQ)
NRZ30_03010	COG2766	serine protein kinase
NRZ30_03015	COG2718	Belongs to the UPF0229 family
NRZ30_03020	COG2719	SpoVR family
NRZ30_03025	COG1024	Enoyl-CoA hydratase
NRZ30_03025	COG1250	3-hydroxyacyl-CoA dehydrogenase
NRZ30_03030	COG0183	Belongs to the thiolase family
NRZ30_03035	COG0714	Associated with various cellular activities
NRZ30_03065	COG1595	DNA-templated transcription, initiation
NRZ30_03075	COG2067	long-chain fatty acid transport protein
NRZ30_03080	COG2067	long-chain fatty acid transport protein
NRZ30_03085	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
NRZ30_03100	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
NRZ30_03110	COG1643	Atp-dependent helicase
NRZ30_03115	COG0517	IMP dehydrogenase activity
NRZ30_03115	COG0617	tRNA 3'-terminal CCA addition
NRZ30_03115	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
NRZ30_03120	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
NRZ30_03125	COG0438	transferase activity, transferring glycosyl groups
NRZ30_03130	COG0297	glycogen (starch) synthase activity
NRZ30_03145	COG0110	maltose O-acetyltransferase activity
NRZ30_03150	COG0438	transferase activity, transferring glycosyl groups
NRZ30_03190	COG0438	transferase activity, transferring glycosyl groups
NRZ30_03195	COG1215	transferase activity, transferring glycosyl groups
NRZ30_03200	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
NRZ30_03240	COG2205	protein histidine kinase activity
NRZ30_03240	COG0784	Response regulator, receiver
NRZ30_03245	COG2925	Exonuclease
NRZ30_03255	COG3345	alpha-galactosidase
NRZ30_03260	COG1380	Effector of murein hydrolase LrgA
NRZ30_03265	COG1346	cytolysis
NRZ30_03270	COG0295	cytidine deaminase activity
NRZ30_03275	COG3033	Beta-eliminating lyase
NRZ30_03285	COG3046	protein related to deoxyribodipyrimidine photolyase
NRZ30_03290	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
NRZ30_03300	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
NRZ30_03325	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
NRZ30_03345	COG0454	-acetyltransferase
NRZ30_03350	COG3158	transport of potassium into the cell
NRZ30_03365	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
NRZ30_03370	COG0651	ATP synthesis coupled electron transport
NRZ30_03375	COG0650	Formate hydrogenlyase subunit 4
NRZ30_03380	COG3261	NADH dehydrogenase
NRZ30_03380	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
NRZ30_03385	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
NRZ30_03390	COG3260	NADH ubiquinone oxidoreductase 20
NRZ30_03400	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
NRZ30_03410	COG1921	L-seryl-tRNASec selenium transferase activity
NRZ30_03420	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
NRZ30_03425	COG0298	carbon dioxide binding
NRZ30_03435	COG0309	Hydrogenase expression formation protein (HypE)
NRZ30_03440	COG0375	protein maturation
NRZ30_03450	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
NRZ30_03460	COG1124	(ABC) transporter
NRZ30_03465	COG0444	Belongs to the ABC transporter superfamily
NRZ30_03470	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
NRZ30_03475	COG0601	transmembrane transport
NRZ30_03485	COG1773	rubredoxin
NRZ30_03490	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
NRZ30_03495	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
NRZ30_03500	COG5557	Pfam Polysulphide reductase, NrfD
NRZ30_03505	COG0437	4 iron, 4 sulfur cluster binding
NRZ30_03510	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
NRZ30_03545	COG0730	response to heat
NRZ30_03555	COG1028	Short-chain dehydrogenase reductase Sdr
NRZ30_03565	COG1024	Enoyl-CoA hydratase
NRZ30_03570	COG1024	Enoyl-CoA hydratase
NRZ30_03580	COG1960	acyl-CoA dehydrogenase activity
NRZ30_03585	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
NRZ30_03590	COG1024	Enoyl-CoA hydratase
NRZ30_03620	COG1584	GPR1 FUN34 yaaH family protein
NRZ30_03625	COG3228	Belongs to the MtfA family
NRZ30_03635	COG1115	amino acid carrier protein
NRZ30_03640	COG1024	Enoyl-CoA hydratase
NRZ30_03655	COG3162	membrane
NRZ30_03660	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
NRZ30_03810	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
NRZ30_03815	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
NRZ30_03965	COG0582	viral genome integration into host DNA
NRZ30_03970	COG0488	(ABC) transporter
NRZ30_03975	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
NRZ30_03980	COG0776	regulation of translation
NRZ30_03985	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
NRZ30_03990	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
NRZ30_03995	COG0740	serine-type endopeptidase activity
NRZ30_04000	COG0544	peptidyl-prolyl cis-trans isomerase activity
NRZ30_04010	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
NRZ30_04015	COG4591	ABC-type transport system involved in lipoprotein release permease component
NRZ30_04020	COG1136	(ABC) transporter
NRZ30_04025	COG4591	ABC-type transport system involved in lipoprotein release permease component
NRZ30_04035	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
NRZ30_04040	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
NRZ30_04045	COG4166	transmembrane transport
NRZ30_04050	COG0697	spore germination
NRZ30_04060	COG2062	phosphohistidine phosphatase, SixA
NRZ30_04070	COG0500	methyltransferase
NRZ30_04090	COG0519	Catalyzes the synthesis of GMP from XMP
NRZ30_04090	COG0518	GMP synthase (glutamine-hydrolyzing) activity
NRZ30_04095	COG0517	IMP dehydrogenase activity
NRZ30_04095	COG0516	GMP reductase activity
NRZ30_04105	COG1696	Membrane protein involved in D-alanine export
NRZ30_04115	COG1570	exodeoxyribonuclease VII activity
NRZ30_04120	COG2188	Transcriptional regulator
NRZ30_04125	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
NRZ30_04125	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
NRZ30_04125	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
NRZ30_04130	COG0383	alpha-mannosidase activity
NRZ30_04135	COG1181	Belongs to the D-alanine--D-alanine ligase family
NRZ30_04145	COG0386	Belongs to the glutathione peroxidase family
NRZ30_04150	COG0513	Belongs to the DEAD box helicase family
NRZ30_04165	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
NRZ30_04170	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
NRZ30_04225	COG5001	Diguanylate cyclase
NRZ30_04225	COG3300	MHYT domain
NRZ30_04240	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
NRZ30_04250	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
NRZ30_04255	COG0563	adenylate kinase activity
NRZ30_04265	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
NRZ30_04270	COG1286	toxin biosynthetic process
NRZ30_04275	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
NRZ30_04280	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
NRZ30_04285	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
NRZ30_04290	COG1674	ftsk spoiiie
NRZ30_04290	COG0531	amino acid
NRZ30_04300	COG0686	Belongs to the AlaDH PNT family
NRZ30_04305	COG0492	ferredoxin-NADP+ reductase activity
NRZ30_04310	COG3706	GGDEF domain
NRZ30_04315	COG3134	Outer membrane lipoprotein
NRZ30_04320	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
NRZ30_04325	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
NRZ30_04330	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
NRZ30_04335	COG0542	response to heat
NRZ30_04340	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
NRZ30_04345	COG1278	Cold shock
NRZ30_04350	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
NRZ30_04370	COG0745	RESPONSE REGULATOR receiver
NRZ30_04375	COG2205	protein histidine kinase activity
NRZ30_04385	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
NRZ30_04385	COG0392	lysyltransferase activity
NRZ30_04395	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
NRZ30_04400	COG2194	sulfuric ester hydrolase activity
NRZ30_04425	COG0672	)-iron permease
NRZ30_04445	COG2814	Major facilitator Superfamily
NRZ30_04455	COG1136	(ABC) transporter
NRZ30_04460	COG0577	efflux transmembrane transporter activity
NRZ30_04485	COG0596	Alpha beta hydrolase
NRZ30_04515	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
NRZ30_04520	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
NRZ30_04520	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
NRZ30_04525	COG0527	aspartate kinase activity
NRZ30_04535	COG1368	sulfuric ester hydrolase activity
NRZ30_04540	COG1619	proteins homologs of microcin C7 resistance protein MccF
NRZ30_04545	COG4667	esterase of the alpha-beta hydrolase superfamily
NRZ30_04565	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
NRZ30_04565	COG1648	precorrin-2 dehydrogenase activity
NRZ30_04575	COG0393	Putative heavy-metal-binding
NRZ30_04580	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
NRZ30_04585	COG0285	dihydrofolate synthase activity
NRZ30_04590	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
NRZ30_04595	COG0101	tRNA pseudouridine synthase activity
NRZ30_04605	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
NRZ30_04610	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
NRZ30_04615	COG0671	phosphoesterase, PA-phosphatase related
NRZ30_04620	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
NRZ30_04625	COG2056	Na+-H+ antiporter family
NRZ30_04635	COG2050	protein possibly involved in aromatic compounds catabolism
NRZ30_04645	COG0247	lactate metabolic process
NRZ30_04645	COG0277	FAD linked oxidase domain protein
NRZ30_04655	COG1253	flavin adenine dinucleotide binding
NRZ30_04660	COG1902	pentaerythritol trinitrate reductase activity
NRZ30_04675	COG0647	UMP catabolic process
NRZ30_04680	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
NRZ30_04680	COG4651	solute:proton antiporter activity
NRZ30_04690	COG0367	asparagine synthase
NRZ30_04695	COG0625	glutathione transferase activity
NRZ30_04705	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
NRZ30_04720	COG0564	pseudouridine synthase activity
NRZ30_04725	COG4160	amino acid transport
NRZ30_04745	COG2431	L-lysine efflux transmembrane transporter activity
NRZ30_04750	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
NRZ30_04765	COG1393	Belongs to the ArsC family
NRZ30_04775	COG4783	chaperone-mediated protein folding
NRZ30_04780	COG0425	Belongs to the sulfur carrier protein TusA family
NRZ30_04805	COG3842	ATPase activity
NRZ30_04810	COG3833	ABC-type maltose transport systems, permease component
NRZ30_04815	COG1175	transmembrane transport
NRZ30_04825	COG3081	Nucleoid-associated protein
NRZ30_04830	COG3082	Protein of unknown function (DUF1414)
NRZ30_04835	COG3083	sulfuric ester hydrolase activity
NRZ30_04840	COG1464	Belongs to the NlpA lipoprotein family
NRZ30_04855	COG0574	Belongs to the PEP-utilizing enzyme family
NRZ30_04855	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
NRZ30_04860	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
NRZ30_04875	COG0546	phosphoglycolate phosphatase activity
NRZ30_04880	COG0840	transmembrane signaling receptor activity
NRZ30_04885	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
NRZ30_04885	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
NRZ30_04890	COG0509	glycine decarboxylation via glycine cleavage system
NRZ30_04895	COG0404	The glycine cleavage system catalyzes the degradation of glycine
NRZ30_04900	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
NRZ30_04905	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
NRZ30_04925	COG0243	molybdopterin cofactor binding
NRZ30_04930	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
NRZ30_04935	COG0583	DNA-binding transcription factor activity
NRZ30_04940	COG2814	Major facilitator Superfamily
NRZ30_04945	COG0625	glutathione transferase activity
NRZ30_04955	COG0483	inositol monophosphate 1-phosphatase activity
NRZ30_04970	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
NRZ30_04980	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
NRZ30_04985	COG1086	Polysaccharide biosynthesis protein
NRZ30_04990	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
NRZ30_04995	COG1213	nucleotidyl transferase
NRZ30_05000	COG0519	Catalyzes the synthesis of GMP from XMP
NRZ30_05005	COG0574	Belongs to the PEP-utilizing enzyme family
NRZ30_05005	COG3848	Pyruvate phosphate dikinase
NRZ30_05015	COG0529	Catalyzes the synthesis of activated sulfate
NRZ30_05035	COG0438	transferase activity, transferring glycosyl groups
NRZ30_05040	COG0438	transferase activity, transferring glycosyl groups
NRZ30_05045	COG0438	transferase activity, transferring glycosyl groups
NRZ30_05060	COG1215	transferase activity, transferring glycosyl groups
NRZ30_05075	COG0318	PFAM AMP-dependent synthetase and ligase
NRZ30_05080	COG1028	Short-chain dehydrogenase reductase Sdr
NRZ30_05095	COG1083	cytidylyl-transferase
NRZ30_05105	COG2089	acid synthase
NRZ30_05120	COG4310	Domain of unknown function (DUF2172)
NRZ30_05170	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
NRZ30_05175	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
NRZ30_05190	COG0301	tRNA thio-modification
NRZ30_05190	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
NRZ30_05200	COG4953	penicillin-binding protein 1C
NRZ30_05205	COG2373	Large extracellular alpha-helical protein
NRZ30_05215	COG0446	pyridine nucleotide-disulphide oxidoreductase
NRZ30_05225	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
NRZ30_05235	COG1252	NADH dehydrogenase
NRZ30_05240	COG3150	esterase
NRZ30_05245	COG2233	PERMEase
NRZ30_05250	COG1164	Oligoendopeptidase f
NRZ30_05255	COG2354	Protein conserved in bacteria
NRZ30_05265	COG1301	dicarboxylic acid transport
NRZ30_05280	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
NRZ30_05295	COG0537	adenosine 5'-monophosphoramidase activity
NRZ30_05330	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
NRZ30_05335	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
NRZ30_05345	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
NRZ30_05350	COG0287	Prephenate dehydrogenase
NRZ30_05350	COG1605	Chorismate mutase
NRZ30_05360	COG1199	ATP-dependent helicase activity
NRZ30_05370	COG0123	including yeast histone deacetylase and acetoin utilization protein
NRZ30_05375	COG0477	Major facilitator Superfamily
NRZ30_05380	COG0477	Major facilitator Superfamily
NRZ30_05385	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
NRZ30_05410	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
NRZ30_05415	COG2197	response regulator
NRZ30_05430	COG2199	diguanylate cyclase activity
NRZ30_05430	COG2203	Gaf domain
NRZ30_05435	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
NRZ30_05440	COG0765	amino acid transport
NRZ30_05465	COG0531	amino acid
NRZ30_05480	COG1253	flavin adenine dinucleotide binding
NRZ30_05485	COG0704	Plays a role in the regulation of phosphate uptake
NRZ30_05490	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
NRZ30_05495	COG0581	inorganic phosphate transmembrane transporter activity
NRZ30_05500	COG0573	inorganic phosphate transmembrane transporter activity
NRZ30_05525	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
NRZ30_05545	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
NRZ30_05550	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
NRZ30_05555	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
NRZ30_05560	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
NRZ30_05585	COG2716	regulation of RNA biosynthetic process
NRZ30_05590	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
NRZ30_05600	COG2239	Acts as a magnesium transporter
NRZ30_05615	COG3951	Flagellar rod assembly protein muramidase FlgJ
NRZ30_05615	COG1705	Flagellar rod assembly protein muramidase FlgJ
NRZ30_05620	COG1706	bacterial-type flagellum-dependent cell motility
NRZ30_05625	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
NRZ30_05635	COG4787	bacterial-type flagellum-dependent cell motility
NRZ30_05655	COG1815	bacterial-type flagellum-dependent cell motility
NRZ30_05660	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
NRZ30_05665	COG0835	chemotaxis
NRZ30_05665	COG0784	Response regulator, receiver
NRZ30_05670	COG1261	Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly
NRZ30_05685	COG0622	Phosphoesterase
NRZ30_05690	COG4166	transmembrane transport
NRZ30_05715	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
NRZ30_05720	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
NRZ30_05725	COG1882	Formate acetyltransferase
NRZ30_05730	COG1349	DNA-binding transcription factor activity
NRZ30_05765	COG1278	Cold shock
NRZ30_05790	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
NRZ30_05790	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
NRZ30_05795	COG1028	Short-chain dehydrogenase reductase Sdr
NRZ30_05800	COG1535	isochorismatase
NRZ30_05800	COG3433	isochorismatase activity
NRZ30_05805	COG1021	2,3-dihydroxybenzoate-AMP ligase
NRZ30_05810	COG1169	isochorismate synthase
NRZ30_05815	COG4771	TonB-dependent receptor
NRZ30_05820	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
NRZ30_05825	COG1609	Transcriptional regulator
NRZ30_05830	COG0741	lytic transglycosylase activity
NRZ30_05840	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
NRZ30_05860	COG2911	Protein conserved in bacteria
NRZ30_05865	COG0729	surface antigen
NRZ30_05875	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
NRZ30_05885	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
NRZ30_05890	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
NRZ30_05895	COG4134	Bacterial extracellular solute-binding protein
NRZ30_05900	COG4135	transport system, permease component
NRZ30_05905	COG4136	ATPase activity
NRZ30_05910	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
NRZ30_05915	COG2951	lytic endotransglycosylase activity
NRZ30_05920	COG0033	Phosphoglucomutase
NRZ30_05925	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
NRZ30_05930	COG0596	Alpha beta hydrolase
NRZ30_05945	COG0716	FMN binding
NRZ30_05955	COG0735	belongs to the Fur family
NRZ30_05960	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
NRZ30_05970	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
NRZ30_05970	COG1263	PTS System
NRZ30_05970	COG2190	(PTS) system
NRZ30_05975	COG0363	glucosamine-6-phosphate deaminase activity
NRZ30_05980	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
NRZ30_05985	COG1940	carbohydrate kinase activity
NRZ30_05985	COG1846	Transcriptional regulator
NRZ30_05995	COG2199	diguanylate cyclase activity
NRZ30_05995	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
NRZ30_06000	COG3275	phosphorelay sensor kinase activity
NRZ30_06005	COG3279	Response regulator of the LytR AlgR family
NRZ30_06010	COG1966	Carbon starvation protein
NRZ30_06020	COG1566	PFAM secretion protein HlyD family protein
NRZ30_06025	COG1061	Type III restriction enzyme res subunit
NRZ30_06030	COG2027	D-alanyl-D-alanine carboxypeptidase
NRZ30_06035	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
NRZ30_06040	COG3021	interspecies interaction between organisms
NRZ30_06050	COG1607	acyl-coa hydrolase
NRZ30_06055	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
NRZ30_06065	COG0674	pyruvate-flavodoxin oxidoreductase activity
NRZ30_06065	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
NRZ30_06065	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
NRZ30_06065	COG1013	pyruvate-flavodoxin oxidoreductase activity
NRZ30_06075	COG3217	Mosc domain protein beta barrel domain protein
NRZ30_06075	COG0633	Ferredoxin
NRZ30_06075	COG3217	Mosc domain protein beta barrel domain protein
NRZ30_06075	COG0633	Ferredoxin
NRZ30_06080	COG0840	transmembrane signaling receptor activity
NRZ30_06085	COG0501	Belongs to the peptidase M48B family
NRZ30_06090	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
NRZ30_06095	COG2226	methyltransferase
NRZ30_06095	COG1073	alpha beta
NRZ30_06100	COG0156	8-amino-7-oxononanoate synthase activity
NRZ30_06105	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
NRZ30_06110	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
NRZ30_06125	COG0017	Asparaginyl-tRNA synthetase
NRZ30_06135	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
NRZ30_06145	COG1473	amidohydrolase
NRZ30_06150	COG3069	C4-dicarboxylate transmembrane transporter activity
NRZ30_06160	COG1393	Belongs to the ArsC family
NRZ30_06165	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
NRZ30_06170	COG1876	peptidase activity
NRZ30_06180	COG3263	regulation of cellular component size
NRZ30_06195	COG1280	lysine exporter protein (LysE YggA)
NRZ30_06225	COG1957	nucleoside hydrolase
NRZ30_06230	COG0564	pseudouridine synthase activity
NRZ30_06240	COG1454	alcohol dehydrogenase
NRZ30_06245	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
NRZ30_06250	COG0702	epimerase
NRZ30_06260	COG0095	Lipoate-protein ligase
NRZ30_06265	COG5001	Diguanylate cyclase
NRZ30_06305	COG1285	pathogenesis
NRZ30_06310	COG0484	heat shock protein binding
NRZ30_06315	COG0443	Heat shock 70 kDa protein
NRZ30_06320	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
NRZ30_06325	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
NRZ30_06330	COG0497	DNA recombination
NRZ30_06335	COG1227	inorganic diphosphatase activity
NRZ30_06340	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NRZ30_06345	COG0577	efflux transmembrane transporter activity
NRZ30_06345	COG1136	(ABC) transporter
NRZ30_06350	COG1538	Outer membrane efflux protein
NRZ30_06365	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
NRZ30_06375	COG1091	dTDP-4-dehydrorhamnose reductase activity
NRZ30_06380	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
NRZ30_06395	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
NRZ30_06395	COG0662	Cupin 2, conserved barrel domain protein
NRZ30_06405	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
NRZ30_06410	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
NRZ30_06415	COG0297	glycogen (starch) synthase activity
NRZ30_06430	COG0110	maltose O-acetyltransferase activity
NRZ30_06440	COG0463	Glycosyl transferase, family 2
NRZ30_06440	COG1216	Glycosyl transferase, family 2
NRZ30_06445	COG2244	polysaccharide biosynthetic process
NRZ30_06455	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
NRZ30_06455	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
NRZ30_06465	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
NRZ30_06475	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
NRZ30_06480	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NRZ30_06485	COG1309	transcriptional regulator
NRZ30_06510	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
NRZ30_06535	COG0813	purine-nucleoside phosphorylase activity
NRZ30_06550	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
NRZ30_06555	COG0083	homoserine kinase activity
NRZ30_06565	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
NRZ30_06570	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
NRZ30_06575	COG1946	Acyl-CoA thioesterase
NRZ30_06585	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
NRZ30_06590	COG1993	acr, cog1993
NRZ30_06610	COG3210	domain, Protein
NRZ30_06625	COG3210	domain, Protein
NRZ30_06640	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
NRZ30_06650	COG0009	L-threonylcarbamoyladenylate synthase
NRZ30_06660	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
NRZ30_06665	COG0512	Glutamine amidotransferase of anthranilate synthase
NRZ30_06665	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
NRZ30_06670	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
NRZ30_06675	COG0134	indole-3-glycerol-phosphate synthase activity
NRZ30_06675	COG0135	phosphoribosylanthranilate isomerase activity
NRZ30_06680	COG0133	tryptophan synthase activity
NRZ30_06685	COG0159	tryptophan synthase activity
NRZ30_06705	COG1988	membrane-bound metal-dependent
NRZ30_06720	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
NRZ30_06740	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
NRZ30_06750	COG0745	RESPONSE REGULATOR receiver
NRZ30_06765	COG4988	ABC transporter
NRZ30_06770	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
NRZ30_06790	COG1720	tRNA m6t6A37 methyltransferase activity
NRZ30_06815	COG3161	chorismate lyase activity
NRZ30_06820	COG3152	Membrane
NRZ30_06845	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
NRZ30_06850	COG1917	Cupin 2, conserved barrel domain protein
NRZ30_06850	COG1396	sequence-specific DNA binding
NRZ30_06865	COG0531	amino acid
NRZ30_06875	COG0531	amino acid
NRZ30_06885	COG1283	sodium-dependent phosphate transmembrane transporter activity
NRZ30_06895	COG2974	May be involved in recombination
NRZ30_06905	COG0420	3'-5' exonuclease activity
NRZ30_06910	COG0419	ATPase involved in DNA repair
NRZ30_06915	COG3384	dioxygenase
NRZ30_06925	COG0469	pyruvate kinase activity
NRZ30_06930	COG1196	nuclear chromosome segregation
NRZ30_06930	COG3264	Mechanosensitive ion channel
NRZ30_06940	COG2190	(PTS) system
NRZ30_06950	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
NRZ30_06955	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
NRZ30_06960	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
NRZ30_06975	COG2770	Histidine kinase
NRZ30_06975	COG3437	response regulator, receiver
NRZ30_06980	COG3409	Peptidoglycan-binding domain 1 protein
NRZ30_06980	COG3267	Type II secretory pathway component ExeA
NRZ30_07000	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
NRZ30_07005	COG1459	type II secretion system
NRZ30_07010	COG2165	general secretion pathway protein
NRZ30_07020	COG2165	general secretion pathway protein
NRZ30_07030	COG3156	type II secretion system protein K
NRZ30_07040	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
NRZ30_07055	COG0670	Belongs to the BI1 family
NRZ30_07060	COG1289	transmembrane transporter activity
NRZ30_07065	COG2920	part of a sulfur-relay system
NRZ30_07070	COG0673	inositol 2-dehydrogenase activity
NRZ30_07080	COG0583	DNA-binding transcription factor activity
NRZ30_07110	COG0326	Molecular chaperone. Has ATPase activity
NRZ30_07120	COG1032	radical SAM domain protein
NRZ30_07125	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
NRZ30_07130	COG1566	PFAM secretion protein HlyD family protein
NRZ30_07135	COG3706	GGDEF domain
NRZ30_07140	COG1752	Esterase of the alpha-beta hydrolase superfamily
NRZ30_07145	COG0531	amino acid
NRZ30_07165	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
NRZ30_07165	COG2885	chlorophyll binding
NRZ30_07170	COG0281	malic enzyme
NRZ30_07180	COG0534	Mate efflux family protein
NRZ30_07195	COG2233	PERMEase
NRZ30_07200	COG1115	amino acid carrier protein
NRZ30_07205	COG0019	diaminopimelate decarboxylase activity
NRZ30_07225	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
NRZ30_07240	COG0545	Peptidyl-prolyl cis-trans isomerase
NRZ30_07245	COG3142	Participates in the control of copper homeostasis
NRZ30_07270	COG5002	protein histidine kinase activity
NRZ30_07275	COG0745	RESPONSE REGULATOR receiver
NRZ30_07280	COG0346	lactoylglutathione lyase activity
NRZ30_07285	COG3706	GGDEF domain
NRZ30_07295	COG0697	spore germination
NRZ30_07305	COG3290	protein histidine kinase activity
NRZ30_07310	COG0281	malic enzyme
NRZ30_07355	COG0602	queuosine metabolic process
NRZ30_07360	COG1328	CTP reductase activity
NRZ30_07370	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
NRZ30_07375	COG3115	cell septum assembly
NRZ30_07380	COG1196	nuclear chromosome segregation
NRZ30_07390	COG2860	membrane
NRZ30_07400	COG3108	Peptidase M15
NRZ30_07405	COG2989	Protein conserved in bacteria
NRZ30_07420	COG0463	Glycosyl transferase, family 2
NRZ30_07435	COG0366	Alpha amylase catalytic
NRZ30_07470	COG2199	diguanylate cyclase activity
NRZ30_07470	COG2203	Gaf domain
NRZ30_07480	COG3590	peptidase
NRZ30_07490	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
NRZ30_07495	COG1982	Orn Lys Arg decarboxylase major
NRZ30_07500	COG0531	amino acid
NRZ30_07510	COG3710	Transcriptional regulator
NRZ30_07515	COG0488	(ABC) transporter
NRZ30_07525	COG0531	amino acid
NRZ30_07545	COG0814	amino acid
NRZ30_07575	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
NRZ30_07580	COG0739	heme binding
NRZ30_07585	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
NRZ30_07615	COG0583	DNA-binding transcription factor activity
NRZ30_07620	COG0604	alcohol dehydrogenase
NRZ30_07620	COG1028	Short-chain dehydrogenase reductase Sdr
NRZ30_07620	COG3321	synthase
NRZ30_07630	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
NRZ30_07640	COG3091	SprT-like family
NRZ30_07650	COG1385	rRNA (uridine-N3-)-methyltransferase activity
NRZ30_07655	COG0189	ligase activity
NRZ30_07665	COG1678	Uncharacterized ACR, COG1678
NRZ30_07670	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
NRZ30_07675	COG3104	oligopeptide transport
NRZ30_07700	COG0714	Associated with various cellular activities
NRZ30_07715	COG1115	amino acid carrier protein
NRZ30_07720	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
NRZ30_07730	COG0825	malonyl-CoA metabolic process
NRZ30_07740	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
NRZ30_07745	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
NRZ30_07750	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
NRZ30_07755	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
NRZ30_07760	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
NRZ30_07770	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
NRZ30_07775	COG0750	zinc metalloprotease
NRZ30_07780	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
NRZ30_07785	COG0575	Belongs to the CDS family
NRZ30_07790	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
NRZ30_07795	COG0233	cytoplasmic translational termination
NRZ30_07800	COG0528	UMP kinase activity
NRZ30_07805	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
NRZ30_07810	COG0052	Belongs to the universal ribosomal protein uS2 family
NRZ30_07815	COG0024	Methionine aminopeptidase
NRZ30_07820	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
NRZ30_07825	COG2171	N-acyltransferase activity
NRZ30_07835	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
NRZ30_07835	COG1263	PTS System
NRZ30_07855	COG0564	pseudouridine synthase activity
NRZ30_07860	COG3098	single-species biofilm formation
NRZ30_07885	COG5595	Zn-ribbon-containing, possibly nucleic-acid-binding protein (DUF2310)
NRZ30_07895	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
NRZ30_07895	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
NRZ30_07910	COG1611	Belongs to the LOG family
NRZ30_07915	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
NRZ30_07920	COG0473	3-isopropylmalate dehydrogenase activity
NRZ30_07930	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
NRZ30_07935	COG2363	Small membrane protein
NRZ30_07945	COG0583	DNA-binding transcription factor activity
NRZ30_07950	COG0840	transmembrane signaling receptor activity
NRZ30_07955	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
NRZ30_07970	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
NRZ30_07975	COG1666	GTP binding
NRZ30_07980	COG3248	Nucleoside-binding outer membrane protein
NRZ30_07990	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
NRZ30_08000	COG2813	Specifically methylates the guanine in position
NRZ30_08005	COG0271	Belongs to the BolA IbaG family
NRZ30_08010	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
NRZ30_08015	COG1805	sodium ion transport
NRZ30_08020	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
NRZ30_08025	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
NRZ30_08030	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
NRZ30_08035	COG2871	sodium ion transport
NRZ30_08040	COG1477	protein flavinylation
NRZ30_08070	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
NRZ30_08085	COG0300	oxidoreductase activity
NRZ30_08095	COG0415	Belongs to the DNA photolyase family
NRZ30_08100	COG0789	Transcriptional regulator
NRZ30_08105	COG3272	Protein of unknown function (DUF1722)
NRZ30_08135	COG0077	Prephenate dehydratase
NRZ30_08135	COG1605	Chorismate mutase
NRZ30_08165	COG0840	transmembrane signaling receptor activity
NRZ30_08175	COG0300	oxidoreductase activity
NRZ30_08200	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
NRZ30_08215	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
NRZ30_08220	COG0737	Belongs to the 5'-nucleotidase family
NRZ30_08225	COG0826	peptidase U32
NRZ30_08230	COG1280	lysine exporter protein (LysE YggA)
NRZ30_08240	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
NRZ30_08250	COG0745	RESPONSE REGULATOR receiver
NRZ30_08260	COG0643	Histidine kinase
NRZ30_08260	COG2198	Histidine kinase
NRZ30_08270	COG0835	chemotaxis
NRZ30_08275	COG0840	transmembrane signaling receptor activity
NRZ30_08285	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
NRZ30_08290	COG2201	protein-glutamate methylesterase activity
NRZ30_08295	COG1185	polyribonucleotide nucleotidyltransferase activity
NRZ30_08300	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
NRZ30_08305	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
NRZ30_08310	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
NRZ30_08315	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
NRZ30_08320	COG0195	Participates in both transcription termination and antitermination
NRZ30_08325	COG0779	Required for maturation of 30S ribosomal subunits
NRZ30_08340	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
NRZ30_08345	COG0149	triose-phosphate isomerase activity
NRZ30_08350	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
NRZ30_08355	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
NRZ30_08365	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
NRZ30_08370	COG1534	Rna-binding protein
NRZ30_08385	COG1360	Flagellar Motor Protein
NRZ30_08385	COG1360	Flagellar Motor Protein
NRZ30_08390	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
NRZ30_08395	COG1722	exodeoxyribonuclease VII activity
NRZ30_08400	COG0142	geranyltranstransferase activity
NRZ30_08405	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
NRZ30_08415	COG0601	transmembrane transport
NRZ30_08420	COG4166	transmembrane transport
NRZ30_08430	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
NRZ30_08435	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
NRZ30_08440	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
NRZ30_08460	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
NRZ30_08460	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
NRZ30_08465	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
NRZ30_08475	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
NRZ30_08490	COG3381	protein complex oligomerization
NRZ30_08510	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
NRZ30_08515	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
NRZ30_08520	COG0511	ligase activity, forming carbon-carbon bonds
NRZ30_08525	COG0439	Biotin carboxylase
NRZ30_08530	COG3924	membrane
NRZ30_08535	COG4145	pantothenate transmembrane transporter activity
NRZ30_08540	COG1263	PTS System
NRZ30_08540	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
NRZ30_08540	COG2190	(PTS) system
NRZ30_08545	COG0583	DNA-binding transcription factor activity
NRZ30_08550	COG0604	alcohol dehydrogenase
NRZ30_08555	COG2264	protein methyltransferase activity
NRZ30_08560	COG0110	maltose O-acetyltransferase activity
NRZ30_08565	COG0778	Nitroreductase
NRZ30_08570	COG1902	pentaerythritol trinitrate reductase activity
NRZ30_08570	COG0446	pyridine nucleotide-disulphide oxidoreductase
NRZ30_08575	COG0616	signal peptide processing
NRZ30_08585	COG4174	ABC transporter (Permease)
NRZ30_08590	COG4239	(ABC) transporter, permease
NRZ30_08595	COG0444	Belongs to the ABC transporter superfamily
NRZ30_08600	COG4608	Belongs to the ABC transporter superfamily
NRZ30_08625	COG3416	Protein conserved in bacteria
NRZ30_08635	COG0741	lytic transglycosylase activity
NRZ30_08650	COG0488	(ABC) transporter
NRZ30_08660	COG2252	PERMEase
NRZ30_08665	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
NRZ30_08670	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
NRZ30_08675	COG0840	transmembrane signaling receptor activity
NRZ30_08685	COG1278	Cold shock
NRZ30_08725	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
NRZ30_08730	COG1162	GTPase activity
NRZ30_08735	COG0688	phosphatidylethanolamine metabolic process
NRZ30_08740	COG4628	conserved protein (DUF2132)
NRZ30_08755	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
NRZ30_08770	COG1073	alpha beta
NRZ30_08775	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
NRZ30_08780	COG2195	Cleaves the N-terminal amino acid of tripeptides
NRZ30_08785	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
NRZ30_08790	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
NRZ30_08795	COG3178	'Phosphotransferase
NRZ30_08800	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
NRZ30_08805	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
NRZ30_08810	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
NRZ30_08815	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
NRZ30_08820	COG2967	ApaG domain
NRZ30_08825	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
NRZ30_08835	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NRZ30_08840	COG3314	Sporulation integral membrane protein YlbJ
NRZ30_08845	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
NRZ30_08850	COG0211	Belongs to the bacterial ribosomal protein bL27 family
NRZ30_08855	COG0261	This protein binds to 23S rRNA in the presence of protein L20
NRZ30_08860	COG0142	geranyltranstransferase activity
NRZ30_08865	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
NRZ30_08870	COG0330	HflC and HflK could
NRZ30_08875	COG0330	HflC and HflK could
NRZ30_08880	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
NRZ30_08885	COG1923	regulation of RNA biosynthetic process
NRZ30_08890	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
NRZ30_08895	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
NRZ30_08905	COG0802	atpase or kinase
NRZ30_08910	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
NRZ30_08910	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
NRZ30_08930	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
NRZ30_08935	COG2011	ABC-type metal ion transport system permease component
NRZ30_08940	COG1464	Belongs to the NlpA lipoprotein family
NRZ30_08950	COG0840	transmembrane signaling receptor activity
NRZ30_08975	COG2198	Histidine kinase
NRZ30_08975	COG0784	Response regulator, receiver
NRZ30_08975	COG5002	protein histidine kinase activity
NRZ30_09010	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
NRZ30_09015	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
NRZ30_09020	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
NRZ30_09025	COG2716	regulation of RNA biosynthetic process
NRZ30_09030	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
NRZ30_09035	COG3013	Belongs to the UPF0304 family
NRZ30_09045	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
NRZ30_09050	COG0280	phosphate acetyltransferase
NRZ30_09050	COG0857	belongs to the CobB CobQ family
NRZ30_09055	COG1555	photosystem II stabilization
NRZ30_09060	COG1210	Utp--glucose-1-phosphate uridylyltransferase
NRZ30_09065	COG3104	oligopeptide transport
NRZ30_09070	COG0745	RESPONSE REGULATOR receiver
NRZ30_09100	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NRZ30_09115	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
NRZ30_09150	COG0440	acetolactate synthase activity
NRZ30_09155	COG0028	Belongs to the TPP enzyme family
NRZ30_09180	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
NRZ30_09185	COG0473	3-isopropylmalate dehydrogenase activity
NRZ30_09190	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
NRZ30_09195	COG0066	3-isopropylmalate dehydratase activity
NRZ30_09215	COG1178	ABC-type Fe3 transport system permease component
NRZ30_09220	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
NRZ30_09225	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
NRZ30_09275	COG0459	protein refolding
NRZ30_09280	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
NRZ30_09285	COG0534	Mate efflux family protein
NRZ30_09290	COG3030	protein affecting phage T7 exclusion by the F plasmid
NRZ30_09295	COG1027	Aspartate ammonia-lyase
NRZ30_09300	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
NRZ30_09305	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
NRZ30_09310	COG0828	Belongs to the bacterial ribosomal protein bS21 family
NRZ30_09315	COG1610	YqeY-like protein
NRZ30_09320	COG0358	DNA primase activity
NRZ30_09325	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
NRZ30_09345	COG0151	Belongs to the GarS family
NRZ30_09350	COG0138	bifunctional purine biosynthesis protein purh
NRZ30_09360	COG3036	rescue of stalled ribosome
NRZ30_09365	COG0635	Involved in the biosynthesis of porphyrin-containing compound
NRZ30_09370	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
NRZ30_09380	COG0673	inositol 2-dehydrogenase activity
NRZ30_09390	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
NRZ30_09395	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
NRZ30_09405	COG0583	DNA-binding transcription factor activity
NRZ30_09410	COG0477	Major facilitator Superfamily
NRZ30_09420	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
NRZ30_09435	COG2425	protein containing a von Willebrand factor type A (vWA) domain
NRZ30_09450	COG0456	acetyltransferase
NRZ30_09455	COG1022	Amp-dependent synthetase and ligase
NRZ30_09465	COG2918	glutathione biosynthetic process
NRZ30_09470	COG0612	Peptidase, M16
NRZ30_09475	COG1238	metal cluster binding
NRZ30_09480	COG0604	alcohol dehydrogenase
NRZ30_09480	COG3321	synthase
NRZ30_09480	COG4221	oxidoreductase activity
NRZ30_09480	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
NRZ30_09505	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
NRZ30_09510	COG0359	binds to the 23S rRNA
NRZ30_09515	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
NRZ30_09520	COG0360	Binds together with S18 to 16S ribosomal RNA
NRZ30_09525	COG1914	H( )-stimulated, divalent metal cation uptake system
NRZ30_09530	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
NRZ30_09540	COG0776	regulation of translation
NRZ30_09545	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
NRZ30_09555	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
NRZ30_09570	COG0560	Phosphoserine phosphatase
NRZ30_09580	COG0813	purine-nucleoside phosphorylase activity
NRZ30_09585	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
NRZ30_09590	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
NRZ30_09595	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
NRZ30_09605	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
NRZ30_09610	COG0084	hydrolase, TatD family'
NRZ30_09615	COG2165	general secretion pathway protein
NRZ30_09625	COG1854	S-ribosylhomocysteine lyase activity
NRZ30_09640	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
NRZ30_09640	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
NRZ30_09700	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
NRZ30_09705	COG1047	Peptidyl-prolyl cis-trans
NRZ30_09710	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
NRZ30_09715	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
NRZ30_09720	COG0196	riboflavin kinase activity
NRZ30_09725	COG0728	peptidoglycan biosynthetic process
NRZ30_09730	COG0268	Binds directly to 16S ribosomal RNA
NRZ30_09735	COG0640	Transcriptional regulator
NRZ30_09740	COG0583	DNA-binding transcription factor activity
NRZ30_09750	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
NRZ30_09755	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
NRZ30_09760	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
NRZ30_09765	COG3605	phosphoenolpyruvate-protein phosphotransferase activity
NRZ30_09770	COG1051	belongs to the nudix hydrolase family
NRZ30_09775	COG3066	DNA modification
NRZ30_09785	COG0335	large ribosomal subunit rRNA binding
NRZ30_09790	COG0336	Belongs to the RNA methyltransferase TrmD family
NRZ30_09795	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
NRZ30_09800	COG0228	four-way junction DNA binding
NRZ30_09805	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
NRZ30_09810	COG4137	Cytochrome C assembly protein
NRZ30_09815	COG4536	flavin adenine dinucleotide binding
NRZ30_09825	COG1017	nitric oxide dioxygenase activity
NRZ30_09825	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
NRZ30_09830	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
NRZ30_09835	COG0039	L-malate dehydrogenase activity
NRZ30_09840	COG4160	amino acid transport
NRZ30_09845	COG4215	(ABC) transporter
NRZ30_09850	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
NRZ30_09855	COG1126	abc transporter atp-binding protein
NRZ30_09860	COG1438	arginine binding
NRZ30_09865	COG2837	iron assimilation
NRZ30_09870	COG3842	ATPase activity
NRZ30_09880	COG1840	ABC-type Fe3 transport system, periplasmic component
NRZ30_09905	COG3022	response to hydroperoxide
NRZ30_09920	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
NRZ30_09925	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
NRZ30_09930	COG0762	integral membrane protein
NRZ30_09935	COG1872	DUF167
NRZ30_09945	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
NRZ30_09950	COG0583	DNA-binding transcription factor activity
NRZ30_09965	COG1929	Belongs to the glycerate kinase type-1 family
NRZ30_09970	COG2610	gluconate transmembrane transporter activity
NRZ30_09975	COG3835	regulator
NRZ30_09980	COG3112	Uncharacterised protein family (UPF0231)
NRZ30_10010	COG0513	Belongs to the DEAD box helicase family
NRZ30_10050	COG1448	Aminotransferase
NRZ30_10065	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
NRZ30_10070	COG1328	CTP reductase activity
NRZ30_10085	COG0543	2 iron, 2 sulfur cluster binding
NRZ30_10085	COG0633	Ferredoxin
NRZ30_10100	COG1215	transferase activity, transferring glycosyl groups
NRZ30_10105	COG0726	polysaccharide deacetylase
NRZ30_10105	COG1649	PFAM Uncharacterised BCR, COG1649
NRZ30_10120	COG0840	transmembrane signaling receptor activity
NRZ30_10125	COG3397	chitin binding
NRZ30_10130	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
NRZ30_10135	COG1126	abc transporter atp-binding protein
NRZ30_10145	COG0765	amino acid transport
NRZ30_10150	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
NRZ30_10155	COG0583	DNA-binding transcription factor activity
NRZ30_10160	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
NRZ30_10165	COG4208	sulfate ABC transporter
NRZ30_10170	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
NRZ30_10180	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
NRZ30_10185	COG3174	membrane
NRZ30_10190	COG0110	maltose O-acetyltransferase activity
NRZ30_10205	COG1011	Hydrolase
NRZ30_10210	COG0494	nUDIX hydrolase
NRZ30_10215	COG1218	3'(2'),5'-bisphosphate nucleotidase
NRZ30_10220	COG0814	amino acid
NRZ30_10225	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NRZ30_10240	COG0626	cystathionine gamma-synthase activity
NRZ30_10245	COG0460	homoserine dehydrogenase
NRZ30_10245	COG0527	aspartate kinase activity
NRZ30_10250	COG0306	phosphate transporter
NRZ30_10255	COG1392	Phosphate transport regulator
NRZ30_10260	COG3025	triphosphatase activity
NRZ30_10265	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
NRZ30_10270	COG2813	Specifically methylates the guanine in position
NRZ30_10275	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
NRZ30_10280	COG0297	glycogen (starch) synthase activity
NRZ30_10320	COG1757	Na H antiporter
NRZ30_10325	COG0316	Belongs to the HesB IscA family
NRZ30_10365	COG1042	CoA-binding domain protein
NRZ30_10365	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
NRZ30_10365	COG0045	succinate-CoA ligase (ADP-forming) activity
NRZ30_10410	COG1396	sequence-specific DNA binding
NRZ30_10440	COG0840	transmembrane signaling receptor activity
NRZ30_10455	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
NRZ30_10460	COG0629	single-stranded DNA binding
NRZ30_10485	COG2252	PERMEase
NRZ30_10490	COG2376	Dihydroxyacetone kinase
NRZ30_10495	COG1461	Dihydroxyacetone kinase
NRZ30_10510	COG3284	Transcriptional regulator
NRZ30_10515	COG2957	Belongs to the agmatine deiminase family
NRZ30_10525	COG0628	permease
NRZ30_10545	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
NRZ30_10550	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
NRZ30_10575	COG0456	acetyltransferase
NRZ30_10580	COG3133	Outer membrane lipoprotein
NRZ30_10585	COG0004	ammonium transporteR
NRZ30_10600	COG3932	Exopolysaccharide synthesis, ExoD
NRZ30_10605	COG0814	amino acid
NRZ30_10620	COG0110	maltose O-acetyltransferase activity
NRZ30_10635	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
NRZ30_10640	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
NRZ30_10645	COG2022	thiamine diphosphate biosynthetic process
NRZ30_10655	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
NRZ30_10660	COG0352	thiamine-phosphate diphosphorylase activity
NRZ30_10665	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
NRZ30_10670	COG0789	Transcriptional regulator
NRZ30_10690	COG0745	RESPONSE REGULATOR receiver
NRZ30_10695	COG0642	Histidine kinase
NRZ30_10700	COG0189	ligase activity
NRZ30_10705	COG1410	methionine synthase
NRZ30_10705	COG0646	methionine synthase
NRZ30_10745	COG0477	Major facilitator Superfamily
NRZ30_10760	COG0312	modulator of DNA gyrase
NRZ30_10765	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
NRZ30_10775	COG3164	Protein of unknown function
NRZ30_10780	COG1530	ribonuclease E activity
NRZ30_10785	COG0424	maF-like protein
NRZ30_10790	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
NRZ30_10795	COG1792	Involved in formation and maintenance of cell shape
NRZ30_10800	COG1077	Cell shape determining protein MreB Mrl
NRZ30_10825	COG4968	Prepilin-type N-terminal cleavage methylation domain
NRZ30_10830	COG4969	Belongs to the N-Me-Phe pilin family
NRZ30_10845	COG1459	type II secretion system
NRZ30_10850	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
NRZ30_10895	COG2200	EAL domain
NRZ30_10895	COG2199	diguanylate cyclase activity
NRZ30_10900	COG2200	EAL domain
NRZ30_10910	COG0387	Pfam Sodium calcium exchanger
NRZ30_10915	COG2986	histidine ammonia-lyase
NRZ30_10920	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
NRZ30_10925	COG0010	Belongs to the arginase family
NRZ30_10930	COG1228	amidohydrolase
NRZ30_10935	COG2188	Transcriptional regulator
NRZ30_10940	COG0288	reversible hydration of carbon dioxide
NRZ30_10950	COG2177	Part of the ABC transporter FtsEX involved in
NRZ30_10955	COG2884	Cell division ATP-binding protein ftsE
NRZ30_10960	COG0552	protein localization to endoplasmic reticulum
NRZ30_10965	COG0742	ribosomal rna small subunit methyltransferase
NRZ30_10990	COG2249	NAD(P)H dehydrogenase (quinone) activity
NRZ30_10995	COG0583	DNA-binding transcription factor activity
NRZ30_11000	COG4221	oxidoreductase activity
NRZ30_11015	COG1770	oligopeptidase
NRZ30_11030	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
NRZ30_11040	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
NRZ30_11050	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
NRZ30_11060	COG2095	MarC family integral membrane protein
NRZ30_11070	COG1301	dicarboxylic acid transport
NRZ30_11095	COG3714	YhhN family
NRZ30_11145	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
NRZ30_11150	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
NRZ30_11155	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
NRZ30_11160	COG0049	tRNA binding
NRZ30_11165	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
NRZ30_11170	COG2168	tRNA wobble position uridine thiolation
NRZ30_11175	COG2923	Belongs to the DsrF TusC family
NRZ30_11180	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
NRZ30_11190	COG2964	Protein conserved in bacteria
NRZ30_11195	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
NRZ30_11200	COG0085	RNA polymerase activity
NRZ30_11205	COG0222	ribosome binding
NRZ30_11210	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
NRZ30_11215	COG0081	regulation of translation
NRZ30_11220	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
NRZ30_11225	COG0250	Participates in transcription elongation, termination and antitermination
NRZ30_11240	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
NRZ30_11265	COG0812	UDP-N-acetylmuramate dehydrogenase activity
NRZ30_11270	COG0569	domain protein
NRZ30_11275	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
NRZ30_11280	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
NRZ30_11290	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
NRZ30_11290	COG4191	Histidine kinase
NRZ30_11295	COG3005	denitrification pathway
NRZ30_11300	COG0243	molybdopterin cofactor binding
NRZ30_11330	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
NRZ30_11345	COG2204	response regulator
NRZ30_11355	COG2205	protein histidine kinase activity
NRZ30_11375	COG5413	integral membrane protein
NRZ30_11385	COG1522	sequence-specific DNA binding
NRZ30_11390	COG2502	aspartate--ammonia ligase
NRZ30_11395	COG0542	response to heat
NRZ30_11405	COG0564	pseudouridine synthase activity
NRZ30_11410	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
NRZ30_11425	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
NRZ30_11430	COG0463	Glycosyl transferase, family 2
NRZ30_11435	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
NRZ30_11435	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
NRZ30_11440	COG0726	polysaccharide deacetylase
NRZ30_11445	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
NRZ30_11450	COG2076	Multidrug Resistance protein
NRZ30_11455	COG2076	Multidrug Resistance protein
NRZ30_11460	COG0446	pyridine nucleotide-disulphide oxidoreductase
NRZ30_11470	COG3681	Belongs to the UPF0597 family
NRZ30_11480	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
NRZ30_11485	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
NRZ30_11490	COG1979	alcohol dehydrogenase
NRZ30_11495	COG2207	Transcriptional regulator
NRZ30_11500	COG3040	lipid binding
NRZ30_11515	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
NRZ30_11535	COG0583	DNA-binding transcription factor activity
NRZ30_11540	COG0688	phosphatidylethanolamine metabolic process
NRZ30_11555	COG0540	Belongs to the ATCase OTCase family
NRZ30_11560	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
NRZ30_11565	COG1438	arginine binding
NRZ30_11570	COG1288	antiporter activity
NRZ30_11575	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
NRZ30_11605	COG0635	Involved in the biosynthesis of porphyrin-containing compound
NRZ30_11615	COG3078	GTPase activator activity
NRZ30_11625	COG0218	Necessary for normal cell division and for the maintenance of normal septation
NRZ30_11635	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
NRZ30_11640	COG0408	coproporphyrinogen oxidase activity
NRZ30_11645	COG0009	L-threonylcarbamoyladenylate synthase
NRZ30_11655	COG0551	DNA topoisomerase type I activity
NRZ30_11660	COG2922	Belongs to the Smg family
NRZ30_11665	COG0758	DNA mediated transformation
NRZ30_11670	COG1652	LysM domain
NRZ30_11675	COG0242	peptide deformylase activity
NRZ30_11680	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
NRZ30_11685	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
NRZ30_11685	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
NRZ30_11690	COG0569	domain protein
NRZ30_11695	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
NRZ30_11700	COG1217	gtp-binding protein TYPA
NRZ30_11705	COG0174	glutamine synthetase
NRZ30_11725	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
NRZ30_11730	COG1322	Protein conserved in bacteria
NRZ30_11750	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
NRZ30_11755	COG0583	DNA-binding transcription factor activity
NRZ30_11760	COG0518	GMP synthase (glutamine-hydrolyzing) activity
NRZ30_11760	COG0519	Catalyzes the synthesis of GMP from XMP
NRZ30_11770	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
NRZ30_11775	COG1396	sequence-specific DNA binding
NRZ30_11780	COG1012	belongs to the aldehyde dehydrogenase family
NRZ30_11790	COG2962	Rard protein
NRZ30_11795	COG2391	methyltransferase activity
NRZ30_11820	COG0129	dihydroxy-acid dehydratase activity
NRZ30_11830	COG3978	acetolactate synthase activity
NRZ30_11840	COG0606	chelatase, subunit chli
NRZ30_11845	COG0204	Acyl-transferase
NRZ30_11850	COG0204	Acyl-transferase
NRZ30_11855	COG1683	Conserved Protein
NRZ30_11865	COG1335	isochorismatase
NRZ30_11875	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
NRZ30_11880	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
NRZ30_11890	COG3084	Protein conserved in bacteria
NRZ30_11895	COG5001	Diguanylate cyclase
NRZ30_11895	COG4251	negative regulation of phosphorylation
NRZ30_11895	COG3706	GGDEF domain
NRZ30_11895	COG2203	Gaf domain
NRZ30_11910	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
NRZ30_11915	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
NRZ30_11920	COG1561	YicC-like family, N-terminal region
NRZ30_11930	COG1566	PFAM secretion protein HlyD family protein
NRZ30_11940	COG0583	DNA-binding transcription factor activity
NRZ30_11960	COG1262	PFAM Formylglycine-generating sulfatase enzyme
NRZ30_11965	COG0385	Bile acid
NRZ30_11970	COG0531	amino acid
NRZ30_11975	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NRZ30_11980	COG0531	amino acid
NRZ30_11985	COG2731	YhcH YjgK YiaL family protein
NRZ30_11990	COG3250	beta-galactosidase activity
NRZ30_11995	COG1609	Transcriptional regulator
NRZ30_12030	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
NRZ30_12035	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
NRZ30_12035	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
NRZ30_12040	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
NRZ30_12045	COG3074	FtsZ-dependent cytokinesis
NRZ30_12055	COG1045	serine acetyltransferase
NRZ30_12065	COG0745	RESPONSE REGULATOR receiver
NRZ30_12070	COG2205	protein histidine kinase activity
NRZ30_12075	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
NRZ30_12080	COG0534	Mate efflux family protein
NRZ30_12095	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
NRZ30_12100	COG2937	Belongs to the GPAT DAPAT family
NRZ30_12105	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
NRZ30_12110	COG3161	chorismate lyase activity
NRZ30_12115	COG1580	Controls the rotational direction of flagella during chemotaxis
NRZ30_12135	COG0604	alcohol dehydrogenase
NRZ30_12140	COG1609	Transcriptional regulator
NRZ30_12145	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
NRZ30_12160	COG1519	Transferase
NRZ30_12165	COG0859	PFAM glycosyl transferase family 9
NRZ30_12170	COG0463	Glycosyl transferase, family 2
NRZ30_12175	COG0859	PFAM glycosyl transferase family 9
NRZ30_12180	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
NRZ30_12185	COG2990	Protein conserved in bacteria
NRZ30_12190	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
NRZ30_12200	COG0267	Belongs to the bacterial ribosomal protein bL33 family
NRZ30_12205	COG0227	Belongs to the bacterial ribosomal protein bL28 family
NRZ30_12210	COG2003	Belongs to the UPF0758 family
NRZ30_12215	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
NRZ30_12220	COG0756	dUTP diphosphatase activity
NRZ30_12225	COG1309	transcriptional regulator
NRZ30_12230	COG0668	transmembrane transport
NRZ30_12235	COG0166	Belongs to the GPI family
NRZ30_12240	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
NRZ30_12290	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
NRZ30_12295	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
NRZ30_12300	COG1739	Uncharacterized protein family UPF0029
NRZ30_12305	COG0006	proline dipeptidase activity
NRZ30_12310	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
NRZ30_12315	COG1024	Enoyl-CoA hydratase
NRZ30_12315	COG1250	3-hydroxyacyl-CoA dehydrogenase
NRZ30_12320	COG0183	Belongs to the thiolase family
NRZ30_12345	COG0425	Belongs to the sulfur carrier protein TusA family
NRZ30_12350	COG0251	oxidation-reduction process
NRZ30_12355	COG2885	chlorophyll binding
NRZ30_12360	COG0840	transmembrane signaling receptor activity
NRZ30_12365	COG2818	Glycosylase
NRZ30_12370	COG0752	glycyl-tRNA synthetase alpha subunit
NRZ30_12375	COG0751	glycine-tRNA ligase activity
NRZ30_12380	COG1715	Restriction endonuclease
NRZ30_12395	COG0840	transmembrane signaling receptor activity
NRZ30_12405	COG1609	Transcriptional regulator
NRZ30_12435	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
NRZ30_12445	COG2960	long-chain fatty acid transporting porin activity
NRZ30_12450	COG5001	Diguanylate cyclase
NRZ30_12460	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
NRZ30_12475	COG3118	belongs to the thioredoxin family
NRZ30_12480	COG0513	Belongs to the DEAD box helicase family
NRZ30_12485	COG0248	Ppx GppA phosphatase
NRZ30_12495	COG0742	ribosomal rna small subunit methyltransferase
NRZ30_12500	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
NRZ30_12525	COG3397	chitin binding
NRZ30_12535	COG0084	hydrolase, TatD family'
NRZ30_12540	COG0805	protein transport
NRZ30_12545	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
NRZ30_12555	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
NRZ30_12565	COG2226	methyltransferase
NRZ30_12570	COG0402	S-adenosylhomocysteine deaminase activity
NRZ30_12575	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
NRZ30_12615	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
NRZ30_12620	COG0848	biopolymer transport protein
NRZ30_12625	COG0811	peptide transport
NRZ30_12630	COG0811	peptide transport
NRZ30_12640	COG2771	luxR family
NRZ30_12645	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
NRZ30_12650	COG1349	DNA-binding transcription factor activity
NRZ30_12655	COG0745	RESPONSE REGULATOR receiver
NRZ30_12660	COG2205	protein histidine kinase activity
NRZ30_12675	COG4452	Inner membrane protein CreD
NRZ30_12690	COG0297	glycogen (starch) synthase activity
NRZ30_12690	COG0438	transferase activity, transferring glycosyl groups
NRZ30_12735	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
NRZ30_12740	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
NRZ30_12745	COG0355	proton-transporting ATP synthase activity, rotational mechanism
NRZ30_12750	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
NRZ30_12755	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
NRZ30_12760	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
NRZ30_12765	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
NRZ30_12770	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
NRZ30_12780	COG0356	it plays a direct role in the translocation of protons across the membrane
NRZ30_12790	COG1475	DNA binding
NRZ30_12795	COG1192	Involved in chromosome partitioning
NRZ30_12800	COG0357	Ribosomal RNA small subunit methyltransferase G
NRZ30_12805	COG0445	tRNA wobble uridine modification
NRZ30_12810	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
NRZ30_12820	COG4615	Cyclic peptide transporter
NRZ30_12825	COG1120	ATPase activity
NRZ30_12830	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
NRZ30_12835	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NRZ30_12840	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
NRZ30_12845	COG0706	membrane insertase activity
NRZ30_12850	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
NRZ30_12855	COG0594	ribonuclease P activity
NRZ30_12860	COG0230	Belongs to the bacterial ribosomal protein bL34 family
NRZ30_12865	COG1126	abc transporter atp-binding protein
NRZ30_12880	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
NRZ30_12885	COG0592	DNA-directed DNA polymerase activity
NRZ30_12905	COG2378	regulation of single-species biofilm formation
NRZ30_12915	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
NRZ30_12920	COG0071	Belongs to the small heat shock protein (HSP20) family
NRZ30_12925	COG0071	Belongs to the small heat shock protein (HSP20) family
NRZ30_12930	COG3977	Valine--pyruvate aminotransferase
NRZ30_12940	COG2814	Major facilitator Superfamily
NRZ30_12945	COG0745	RESPONSE REGULATOR receiver
NRZ30_12950	COG2205	protein histidine kinase activity
NRZ30_12970	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
NRZ30_12975	COG4191	Histidine kinase
NRZ30_12975	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
NRZ30_12980	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
NRZ30_12985	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NRZ30_12990	COG1309	transcriptional regulator
NRZ30_13025	COG0561	phosphatase activity
NRZ30_13030	COG2267	carboxylic ester hydrolase activity
NRZ30_13035	COG0110	maltose O-acetyltransferase activity
NRZ30_13040	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
NRZ30_13045	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
NRZ30_13050	COG1758	RNA polymerase activity
NRZ30_13060	COG0859	PFAM glycosyl transferase family 9
NRZ30_13065	COG3642	lipopolysaccharide core region biosynthetic process
NRZ30_13105	COG0589	response to stress
NRZ30_13110	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
NRZ30_13115	COG1528	Iron-storage protein
NRZ30_13120	COG2081	HI0933 family
NRZ30_13125	COG3275	phosphorelay sensor kinase activity
NRZ30_13130	COG3279	Response regulator of the LytR AlgR family
NRZ30_13135	COG2223	nitrite transmembrane transporter activity
NRZ30_13140	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
NRZ30_13145	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
NRZ30_13160	COG0583	DNA-binding transcription factor activity
NRZ30_13165	COG4206	TonB-dependent receptor
NRZ30_13205	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
NRZ30_13210	COG2166	iron-sulfur cluster assembly
NRZ30_13215	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
NRZ30_13230	COG3245	cytochrome
NRZ30_13235	COG1063	alcohol dehydrogenase
NRZ30_13240	COG0156	8-amino-7-oxononanoate synthase activity
NRZ30_13250	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
NRZ30_13270	COG3306	glycosyltransferase involved in LPS biosynthesis
NRZ30_13300	COG1280	lysine exporter protein (LysE YggA)
NRZ30_13360	COG0210	DNA helicase
NRZ30_13365	COG1744	ABC transporter substrate-binding protein PnrA-like
NRZ30_13370	COG3845	ABC transporter
NRZ30_13375	COG4603	Belongs to the binding-protein-dependent transport system permease family
NRZ30_13380	COG1079	Belongs to the binding-protein-dependent transport system permease family
NRZ30_13385	COG2239	Acts as a magnesium transporter
NRZ30_13390	COG1648	precorrin-2 dehydrogenase activity
NRZ30_13390	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
NRZ30_13395	COG2116	formate transmembrane transporter activity
NRZ30_13405	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
NRZ30_13410	COG0842	Transport permease protein
NRZ30_13415	COG0842	Transport permease protein
NRZ30_13420	COG1131	(ABC) transporter
NRZ30_13425	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NRZ30_13435	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
NRZ30_13440	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
NRZ30_13460	COG1595	DNA-templated transcription, initiation
NRZ30_13470	COG1968	undecaprenyl-diphosphatase activity
NRZ30_13475	COG2017	converts alpha-aldose to the beta-anomer
NRZ30_13480	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
NRZ30_13485	COG1085	galactose-1-phosphate uridylyltransferase
NRZ30_13490	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
NRZ30_13495	COG1609	Transcriptional regulator
NRZ30_13500	COG3250	beta-galactosidase activity
NRZ30_13525	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
NRZ30_13540	COG0366	Alpha amylase catalytic
NRZ30_13555	COG0443	Heat shock 70 kDa protein
NRZ30_13560	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NRZ30_13565	COG3045	CreA protein
NRZ30_13585	COG0174	glutamine synthetase
NRZ30_13605	COG3842	ATPase activity
NRZ30_13610	COG1176	ABC-type spermidine putrescine transport system, permease component I
NRZ30_13615	COG1177	transmembrane transport
NRZ30_13620	COG2258	MOSC domain
NRZ30_13635	COG2050	protein possibly involved in aromatic compounds catabolism
NRZ30_13640	COG0514	ATP-dependent DNA helicase (RecQ)
NRZ30_13650	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
NRZ30_13660	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
NRZ30_13665	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
NRZ30_13680	COG0254	rRNA binding
NRZ30_13685	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
NRZ30_13695	COG0702	epimerase
NRZ30_13700	COG0814	amino acid
NRZ30_13705	COG0281	malic enzyme
NRZ30_13710	COG1295	ribonuclease BN
NRZ30_13715	COG1490	D-aminoacyl-tRNA deacylase activity
NRZ30_13720	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
NRZ30_13725	COG0456	acetyltransferase
NRZ30_13735	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
NRZ30_13740	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
NRZ30_13745	COG2610	gluconate transmembrane transporter activity
NRZ30_13750	COG3265	gluconokinase activity
NRZ30_13760	COG0800	Aldolase
NRZ30_13775	COG1609	Transcriptional regulator
NRZ30_13785	COG4942	peptidase
NRZ30_13790	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
NRZ30_13795	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
NRZ30_13800	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
NRZ30_13805	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
NRZ30_13810	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
NRZ30_13810	COG0316	Belongs to the HesB IscA family
NRZ30_13815	COG1040	competence protein
NRZ30_13820	COG0596	Alpha beta hydrolase
NRZ30_13840	COG2183	response to ionizing radiation
NRZ30_13845	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
NRZ30_13865	COG0051	transcription antitermination factor activity, RNA binding
NRZ30_13870	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
NRZ30_13875	COG0088	Forms part of the polypeptide exit tunnel
NRZ30_13880	COG0089	rRNA binding
NRZ30_13885	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
NRZ30_13890	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
NRZ30_13895	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
NRZ30_13900	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
NRZ30_13905	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
NRZ30_13910	COG0255	Belongs to the universal ribosomal protein uL29 family
NRZ30_13915	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
NRZ30_13920	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
NRZ30_13925	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
NRZ30_13930	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
NRZ30_13935	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
NRZ30_13940	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
NRZ30_13945	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
NRZ30_13950	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
NRZ30_13955	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
NRZ30_13960	COG1841	ribosomal large subunit assembly
NRZ30_13965	COG0200	Binds to the 23S rRNA
NRZ30_13970	COG0201	protein transport
NRZ30_13975	COG0257	Belongs to the bacterial ribosomal protein bL36 family
NRZ30_13980	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
NRZ30_13985	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
NRZ30_13990	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
NRZ30_13995	COG0202	RNA polymerase activity
NRZ30_14000	COG0203	ribosomal protein L17
NRZ30_14035	COG4771	TonB-dependent receptor
NRZ30_14040	COG3706	GGDEF domain
NRZ30_14060	COG0583	DNA-binding transcription factor activity
NRZ30_14070	COG1741	Belongs to the pirin family
NRZ30_14075	COG2259	Doxx family
NRZ30_14080	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
NRZ30_14085	COG1074	ATP-dependent DNA helicase activity
NRZ30_14090	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
NRZ30_14105	COG2199	diguanylate cyclase activity
NRZ30_14105	COG2203	Gaf domain
NRZ30_14120	COG3069	C4-dicarboxylate transmembrane transporter activity
NRZ30_14145	COG1175	transmembrane transport
NRZ30_14155	COG3842	ATPase activity
NRZ30_14185	COG2873	o-acetylhomoserine
NRZ30_14210	COG5380	lipid catabolic process
NRZ30_14215	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
NRZ30_14220	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
NRZ30_14245	COG0456	acetyltransferase
NRZ30_14245	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
NRZ30_14250	COG0454	-acetyltransferase
NRZ30_14250	COG0456	acetyltransferase
NRZ30_14275	COG2927	DNA polymerase III (CHI subunit)
NRZ30_14280	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
NRZ30_14285	COG0795	lipopolysaccharide-transporting ATPase activity
NRZ30_14290	COG0795	lipopolysaccharide-transporting ATPase activity
NRZ30_14320	COG1686	Belongs to the peptidase S11 family
NRZ30_14345	COG1494	fructose-1,6-bisphosphatase
NRZ30_14360	COG2959	enzyme of heme biosynthesis
NRZ30_14370	COG0181	hydroxymethylbilane synthase activity
NRZ30_14375	COG3072	Adenylate cyclase
NRZ30_14380	COG0400	carboxylic ester hydrolase activity
NRZ30_14385	COG1965	Belongs to the frataxin family
NRZ30_14395	COG0019	diaminopimelate decarboxylase activity
NRZ30_14400	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
NRZ30_14415	COG1011	Hydrolase
NRZ30_14420	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
NRZ30_14430	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
NRZ30_14435	COG3028	Belongs to the UPF0307 family
NRZ30_14440	COG0312	modulator of DNA gyrase
NRZ30_14445	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
NRZ30_14450	COG5007	Belongs to the BolA IbaG family
NRZ30_14460	COG2854	intermembrane phospholipid transfer
NRZ30_14465	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
NRZ30_14470	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
NRZ30_14475	COG1127	ABC transporter
NRZ30_14480	COG0517	IMP dehydrogenase activity
NRZ30_14480	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
NRZ30_14485	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
NRZ30_14495	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
NRZ30_14500	COG1137	ATPase activity
NRZ30_14505	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
NRZ30_14515	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
NRZ30_14520	COG1660	Displays ATPase and GTPase activities
NRZ30_14525	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
NRZ30_14530	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
NRZ30_14530	COG3711	transcriptional antiterminator
NRZ30_14545	COG3964	amidohydrolase
NRZ30_14575	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
NRZ30_14580	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
NRZ30_14590	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
NRZ30_14595	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
NRZ30_14600	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
NRZ30_14605	COG0723	plastoquinol--plastocyanin reductase activity
NRZ30_14610	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
NRZ30_14615	COG2857	Cytochrome c1
NRZ30_14620	COG0625	glutathione transferase activity
NRZ30_14625	COG2969	positive regulation of protein catabolic process
NRZ30_14635	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
NRZ30_14640	COG0792	nuclease activity
NRZ30_14645	COG3107	peptidoglycan biosynthetic process
NRZ30_14650	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
NRZ30_14700	COG1677	Flagellar hook-basal body complex protein FliE
NRZ30_14710	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
NRZ30_14735	COG2747	anti-sigma28 factor FlgM
NRZ30_14745	COG1815	bacterial-type flagellum-dependent cell motility
NRZ30_14770	COG4786	Flagellar basal body rod
NRZ30_14775	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
NRZ30_14780	COG1706	bacterial-type flagellum-dependent cell motility
NRZ30_14790	COG1256	bacterial-type flagellum assembly
NRZ30_14790	COG4786	Flagellar basal body rod
NRZ30_14795	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
NRZ30_14815	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
NRZ30_14820	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
NRZ30_14845	COG1191	sigma factor activity
NRZ30_14850	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
NRZ30_14855	COG1360	Flagellar Motor Protein
NRZ30_14860	COG0741	lytic transglycosylase activity
NRZ30_14860	COG1388	LysM domain
NRZ30_14870	COG2001	Belongs to the MraZ family
NRZ30_14875	COG0275	rRNA processing
NRZ30_14880	COG3116	cell division
NRZ30_14885	COG0768	penicillin binding
NRZ30_14890	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
NRZ30_14895	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
NRZ30_14900	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
NRZ30_14905	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
NRZ30_14910	COG0772	Belongs to the SEDS family
NRZ30_14915	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
NRZ30_14920	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
NRZ30_14930	COG0849	cell division
NRZ30_14935	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
NRZ30_14940	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
NRZ30_14950	COG0653	protein targeting
NRZ30_14955	COG0494	nUDIX hydrolase
NRZ30_14960	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
NRZ30_14965	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
NRZ30_14980	COG1459	type II secretion system
NRZ30_14985	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
NRZ30_15010	COG2186	Transcriptional regulator
NRZ30_15015	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
NRZ30_15020	COG0508	dehydrogenase complex catalyzes the overall conversion of
NRZ30_15025	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
NRZ30_15035	COG0840	transmembrane signaling receptor activity
NRZ30_15040	COG1752	Esterase of the alpha-beta hydrolase superfamily
NRZ30_15045	COG1049	propionate catabolic process, 2-methylcitrate cycle
NRZ30_15050	COG2200	EAL domain
NRZ30_15060	COG0523	cobalamin synthesis protein
NRZ30_15065	COG0477	Major facilitator Superfamily
NRZ30_15075	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
NRZ30_15080	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
NRZ30_15105	COG3314	Sporulation integral membrane protein YlbJ
NRZ30_15120	COG0165	Argininosuccinate lyase
NRZ30_15125	COG0137	argininosuccinate synthase activity
NRZ30_15135	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
NRZ30_15140	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
NRZ30_15150	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
NRZ30_15175	COG0583	DNA-binding transcription factor activity
NRZ30_15195	COG1380	Effector of murein hydrolase LrgA
NRZ30_15200	COG1346	cytolysis
NRZ30_15210	COG4667	esterase of the alpha-beta hydrolase superfamily
NRZ30_15215	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
NRZ30_15220	COG1546	Belongs to the CinA family
NRZ30_15225	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
NRZ30_15235	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
NRZ30_15240	COG0527	aspartate kinase activity
NRZ30_15245	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
NRZ30_15280	COG1686	Belongs to the peptidase S11 family
NRZ30_15285	COG0586	Pfam SNARE associated Golgi protein
NRZ30_15290	COG1253	flavin adenine dinucleotide binding
NRZ30_15295	COG0252	asparaginase activity
NRZ30_15300	COG2217	Heavy metal translocating P-type atpase
NRZ30_15300	COG2608	mercury ion transmembrane transporter activity
NRZ30_15315	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
NRZ30_15315	COG1263	PTS System
NRZ30_15320	COG0366	Alpha amylase catalytic
NRZ30_15325	COG0110	maltose O-acetyltransferase activity
NRZ30_15335	COG0564	pseudouridine synthase activity
NRZ30_15340	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
NRZ30_15375	COG2926	Belongs to the UPF0265 family
NRZ30_15385	COG0561	phosphatase activity
NRZ30_15395	COG1058	Belongs to the CinA family
NRZ30_15395	COG1546	Belongs to the CinA family
NRZ30_15400	COG1418	mRNA catabolic process
NRZ30_15405	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
NRZ30_15415	COG1522	sequence-specific DNA binding
NRZ30_15420	COG1368	sulfuric ester hydrolase activity
NRZ30_15440	COG1285	pathogenesis
NRZ30_15460	COG4221	oxidoreductase activity
NRZ30_15475	COG1979	alcohol dehydrogenase
NRZ30_15480	COG1803	Methylglyoxal synthase
NRZ30_15500	COG1444	tRNA N-acetyltransferase activity
NRZ30_15510	COG0784	Response regulator, receiver
NRZ30_15510	COG0835	chemotaxis
NRZ30_15520	COG3291	Pkd domain containing protein
NRZ30_15525	COG0318	PFAM AMP-dependent synthetase and ligase
NRZ30_15535	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
NRZ30_15540	COG0596	Alpha beta hydrolase
NRZ30_15545	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
NRZ30_15550	COG1169	isochorismate synthase
NRZ30_15555	COG1575	Belongs to the MenA family. Type 1 subfamily
NRZ30_15575	COG0513	Belongs to the DEAD box helicase family
NRZ30_15580	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
NRZ30_15585	COG1988	membrane-bound metal-dependent
NRZ30_15600	COG1671	Belongs to the UPF0178 family
NRZ30_15625	COG3722	fumarate hydratase activity
NRZ30_15630	COG0246	Mannitol dehydrogenase
NRZ30_15635	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
NRZ30_15635	COG2213	PTS system mannitol-specific
NRZ30_15640	COG1560	Kdo2-lipid A biosynthetic process
NRZ30_15645	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
NRZ30_15645	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
NRZ30_15650	COG1538	Outer membrane efflux protein
NRZ30_15655	COG0494	nUDIX hydrolase
NRZ30_15660	COG3151	Protein conserved in bacteria
NRZ30_15670	COG3150	esterase
NRZ30_15675	COG1051	belongs to the nudix hydrolase family
NRZ30_15685	COG1566	PFAM secretion protein HlyD family protein
NRZ30_15690	COG1289	transmembrane transporter activity
NRZ30_15695	COG0187	DNA topoisomerase II activity
NRZ30_15715	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
NRZ30_15725	COG3104	oligopeptide transport
NRZ30_15770	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
NRZ30_15790	COG0204	Acyl-transferase
NRZ30_15800	COG1842	Phage shock protein A
NRZ30_15815	COG2827	Endonuclease containing a URI domain
NRZ30_15830	COG1573	uracil-dna glycosylase
NRZ30_15835	COG0697	spore germination
NRZ30_15840	COG0583	DNA-binding transcription factor activity
NRZ30_15845	COG1108	ABC-type Mn2 Zn2 transport systems permease components
NRZ30_15850	COG1121	(ABC) transporter
NRZ30_15855	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
NRZ30_15875	COG0739	heme binding
NRZ30_15885	COG3068	Protein conserved in bacteria
NRZ30_15905	COG0617	tRNA 3'-terminal CCA addition
NRZ30_15910	COG1194	a g-specific adenine glycosylase
NRZ30_15915	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
NRZ30_15930	COG3240	lipase activity
NRZ30_15940	COG3706	GGDEF domain
NRZ30_15945	COG0557	exoribonuclease II activity
NRZ30_15950	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
NRZ30_15965	COG2153	protein acetylation
NRZ30_15970	COG0513	Belongs to the DEAD box helicase family
NRZ30_15975	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
NRZ30_16000	COG0735	belongs to the Fur family
NRZ30_16005	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
NRZ30_16015	COG4166	transmembrane transport
NRZ30_16025	COG0110	maltose O-acetyltransferase activity
NRZ30_16035	COG1024	Enoyl-CoA hydratase
NRZ30_16050	COG4221	oxidoreductase activity
NRZ30_16055	COG0442	prolyl-tRNA aminoacylation
NRZ30_16060	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
NRZ30_16065	COG3009	Protein conserved in bacteria
NRZ30_16070	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
NRZ30_16070	COG3008	intermembrane lipid transfer
NRZ30_16075	COG2995	paraquat-inducible protein a
NRZ30_16085	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
NRZ30_16095	COG2203	Gaf domain
NRZ30_16095	COG3706	GGDEF domain
NRZ30_16095	COG4251	negative regulation of phosphorylation
NRZ30_16095	COG5001	Diguanylate cyclase
NRZ30_16100	COG4776	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction
NRZ30_16115	COG2771	luxR family
NRZ30_16125	COG0840	transmembrane signaling receptor activity
NRZ30_16130	COG0632	four-way junction helicase activity
NRZ30_16135	COG2255	four-way junction helicase activity
NRZ30_16145	COG1294	oxidase, subunit
NRZ30_16150	COG4890	Cyd operon protein YbgT
NRZ30_16155	COG3790	cyd operon protein YbgE
NRZ30_16160	COG0824	Thioesterase
NRZ30_16165	COG0811	peptide transport
NRZ30_16180	COG0823	Involved in the tonB-independent uptake of proteins
NRZ30_16185	COG2885	chlorophyll binding
NRZ30_16190	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
NRZ30_16255	COG0733	neurotransmitter:sodium symporter activity
NRZ30_16265	COG0733	neurotransmitter:sodium symporter activity
NRZ30_16280	COG0561	phosphatase activity
NRZ30_16305	COG1051	belongs to the nudix hydrolase family
NRZ30_16325	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
NRZ30_16330	COG1640	4-alpha-glucanotransferase
NRZ30_16335	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
NRZ30_16345	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
NRZ30_16350	COG0840	transmembrane signaling receptor activity
NRZ30_16355	COG1585	Membrane protein implicated in regulation of membrane protease activity
NRZ30_16360	COG0330	HflC and HflK could
NRZ30_16365	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
NRZ30_16365	COG1648	precorrin-2 dehydrogenase activity
NRZ30_16370	COG0175	sulfate reduction
NRZ30_16375	COG2895	sulfate adenylyltransferase (ATP) activity
NRZ30_16380	COG0529	Catalyzes the synthesis of activated sulfate
NRZ30_16415	COG0840	transmembrane signaling receptor activity
NRZ30_16450	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
NRZ30_16465	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
NRZ30_16470	COG0784	Response regulator, receiver
NRZ30_16470	COG3437	response regulator, receiver
NRZ30_16480	COG2076	Multidrug Resistance protein
NRZ30_16485	COG2076	Multidrug Resistance protein
NRZ30_16490	COG0346	lactoylglutathione lyase activity
NRZ30_16495	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
NRZ30_16500	COG1643	Atp-dependent helicase
NRZ30_16510	COG1489	DNA binding
NRZ30_16515	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
NRZ30_16520	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
NRZ30_16530	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
NRZ30_16535	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
NRZ30_16540	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
NRZ30_16545	COG1823	symporter activity
NRZ30_16565	COG1924	4 iron, 4 sulfur cluster binding
NRZ30_16570	COG1775	2-hydroxyglutaryl-CoA dehydratase, D-component
NRZ30_16575	COG0842	Transport permease protein
NRZ30_16580	COG1131	(ABC) transporter
NRZ30_16595	COG0163	prenyltransferase activity
NRZ30_16600	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
NRZ30_16605	COG0671	phosphoesterase, PA-phosphatase related
NRZ30_16610	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
NRZ30_16615	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
NRZ30_16620	COG1151	hydroxylamine reductase activity
NRZ30_16625	COG0783	Belongs to the Dps family
NRZ30_16630	COG3023	N-Acetylmuramoyl-L-alanine amidase
NRZ30_16635	COG4807	Protein conserved in bacteria
NRZ30_16645	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
NRZ30_16650	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
NRZ30_16655	COG3956	TIGRFAM MazG family protein
NRZ30_16660	COG0504	CTP synthase activity
NRZ30_16665	COG0148	phosphopyruvate hydratase activity
NRZ30_16675	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
NRZ30_16705	COG0583	DNA-binding transcription factor activity
NRZ30_16710	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
NRZ30_16720	COG0488	(ABC) transporter
NRZ30_16740	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
NRZ30_16755	COG1794	racemase activity, acting on amino acids and derivatives
NRZ30_16765	COG2731	YhcH YjgK YiaL family protein
NRZ30_16775	COG0668	transmembrane transport
NRZ30_16780	COG1376	ErfK ybiS ycfS ynhG family protein
NRZ30_16790	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
NRZ30_16795	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
NRZ30_16800	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
NRZ30_16810	COG0585	pseudouridine synthase activity
NRZ30_16815	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
NRZ30_16820	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
NRZ30_16825	COG1238	metal cluster binding
NRZ30_16830	COG4942	peptidase
NRZ30_16830	COG1388	LysM domain
NRZ30_16840	COG1902	pentaerythritol trinitrate reductase activity
NRZ30_16855	COG2957	Belongs to the agmatine deiminase family
NRZ30_16860	COG0154	amidase activity
NRZ30_16880	COG0471	metal ion transport
NRZ30_16890	COG0513	Belongs to the DEAD box helicase family
NRZ30_16895	COG2199	diguanylate cyclase activity
NRZ30_16895	COG2203	Gaf domain
NRZ30_16905	COG1912	Pfam S-adenosyl-l-methionine hydroxide adenosyltransferase
NRZ30_16980	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
NRZ30_16995	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
NRZ30_17000	COG4991	sh3 domain protein
NRZ30_17015	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
NRZ30_17020	COG1940	carbohydrate kinase activity
NRZ30_17025	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
NRZ30_17030	COG0126	phosphoglycerate kinase activity
NRZ30_17035	COG0191	fructose-bisphosphate aldolase activity
NRZ30_17040	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
NRZ30_17085	COG0354	folic acid binding
NRZ30_17100	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
NRZ30_17105	COG1595	DNA-templated transcription, initiation
NRZ30_17110	COG3073	An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E
NRZ30_17115	COG3026	antisigma factor binding
NRZ30_17125	COG0481	GTPase activity
NRZ30_17130	COG0681	Belongs to the peptidase S26 family
NRZ30_17145	COG1381	Involved in DNA repair and RecF pathway recombination
NRZ30_17150	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
NRZ30_17160	COG2350	Protein conserved in bacteria
NRZ30_17165	COG2917	probably involved in intracellular septation
NRZ30_17170	COG0076	glutamate decarboxylase activity
NRZ30_17175	COG1272	protein, Hemolysin III
NRZ30_17180	COG0569	domain protein
NRZ30_17180	COG2985	domain, Protein
NRZ30_17200	COG3076	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome
NRZ30_17220	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
NRZ30_17225	COG1028	Short-chain dehydrogenase reductase Sdr
NRZ30_17230	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
NRZ30_17235	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
NRZ30_17270	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
NRZ30_17285	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
NRZ30_17320	COG2313	pseudouridylate synthase activity
NRZ30_17325	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
NRZ30_17365	COG1765	OsmC-like protein
NRZ30_17380	COG3954	Phosphoribulokinase
NRZ30_17385	COG3089	Belongs to the UPF0270 family
NRZ30_17390	COG5001	Diguanylate cyclase
NRZ30_17390	COG4251	negative regulation of phosphorylation
NRZ30_17390	COG3706	GGDEF domain
NRZ30_17390	COG2203	Gaf domain
NRZ30_17395	COG0429	hydrolase of the alpha beta-hydrolase fold
NRZ30_17400	COG0784	Response regulator, receiver
NRZ30_17400	COG0835	chemotaxis
NRZ30_17410	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
NRZ30_17415	COG1047	Peptidyl-prolyl cis-trans
NRZ30_17430	COG0545	Peptidyl-prolyl cis-trans isomerase
NRZ30_17435	COG2204	response regulator
NRZ30_17455	COG0737	Belongs to the 5'-nucleotidase family
NRZ30_17470	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
NRZ30_17480	COG3340	Belongs to the peptidase S51 family
NRZ30_17485	COG1966	Carbon starvation protein
NRZ30_17490	COG3279	Response regulator of the LytR AlgR family
NRZ30_17495	COG3275	phosphorelay sensor kinase activity
NRZ30_17510	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NRZ30_17520	COG3721	Heme iron utilization protein
NRZ30_17525	COG0748	coenzyme F420 binding
NRZ30_17550	COG2771	luxR family
NRZ30_17570	COG3179	chitinase
NRZ30_17580	COG2814	Major facilitator Superfamily
NRZ30_17590	COG3655	Transcriptional regulator
NRZ30_17600	COG0784	Response regulator, receiver
NRZ30_17600	COG2205	protein histidine kinase activity
NRZ30_17600	COG5002	protein histidine kinase activity
NRZ30_17615	COG3397	chitin binding
NRZ30_17655	COG0784	Response regulator, receiver
NRZ30_17655	COG0835	chemotaxis
NRZ30_17660	COG2755	lipolytic protein G-D-S-L family
NRZ30_17665	COG4181	ATPase activity
NRZ30_17670	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
NRZ30_17675	COG1090	epimerase
NRZ30_17680	COG2200	EAL domain
NRZ30_17685	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
NRZ30_17690	COG0220	tRNA (guanine-N7-)-methyltransferase activity
NRZ30_17695	COG3171	Protein conserved in bacteria
NRZ30_17700	COG2066	Belongs to the glutaminase family
NRZ30_17705	COG2897	thiosulfate sulfurtransferase activity
NRZ30_17720	COG0521	Mo-molybdopterin cofactor biosynthetic process
NRZ30_17730	COG2966	Psort location CytoplasmicMembrane, score
NRZ30_17735	COG3610	response to peptide
NRZ30_17745	COG0175	sulfate reduction
NRZ30_17750	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
NRZ30_17755	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
NRZ30_17760	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
NRZ30_17775	COG0786	glutamate:sodium symporter activity
NRZ30_17780	COG0252	asparaginase activity
NRZ30_17785	COG3139	Protein of unknown function (DUF1315)
NRZ30_17805	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
NRZ30_17810	COG0321	lipoyl(octanoyl) transferase activity
NRZ30_17815	COG2921	Belongs to the UPF0250 family
NRZ30_17820	COG1686	Belongs to the peptidase S11 family
NRZ30_17825	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
NRZ30_17830	COG2951	lytic endotransglycosylase activity
NRZ30_17835	COG0772	Belongs to the SEDS family
NRZ30_17840	COG0768	penicillin binding
NRZ30_17845	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
NRZ30_17850	COG0799	negative regulation of ribosome biogenesis
NRZ30_17855	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
NRZ30_17870	COG0495	leucyl-tRNA aminoacylation
NRZ30_17875	COG2888	peptidyl-tyrosine sulfation
NRZ30_17885	COG0312	modulator of DNA gyrase
NRZ30_17895	COG0716	FMN binding
NRZ30_17900	COG4974	Belongs to the 'phage' integrase family
NRZ30_17910	COG1970	mechanosensitive ion channel activity
NRZ30_17930	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
NRZ30_17935	COG0815	Transfers the fatty acyl group on membrane lipoproteins
NRZ30_17940	COG4535	Mg2 and Co2 transporter CorC
NRZ30_17945	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
NRZ30_17950	COG1702	phosphate starvation-inducible protein PhoH
NRZ30_17955	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
NRZ30_17960	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
NRZ30_17965	COG1335	isochorismatase
NRZ30_17975	COG3706	GGDEF domain
NRZ30_18000	COG3706	GGDEF domain
NRZ30_18010	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NRZ30_18020	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
NRZ30_18030	COG0516	GMP reductase activity
NRZ30_18055	COG1028	Short-chain dehydrogenase reductase Sdr
NRZ30_18065	COG0318	PFAM AMP-dependent synthetase and ligase
NRZ30_18080	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
NRZ30_18095	COG3214	Protein conserved in bacteria
NRZ30_18105	COG2195	Cleaves the N-terminal amino acid of tripeptides
NRZ30_18110	COG0700	Nucleoside recognition
NRZ30_18115	COG3366	ferrous iron transmembrane transporter activity
NRZ30_18120	COG3080	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
NRZ30_18125	COG3029	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
NRZ30_18130	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
NRZ30_18135	COG1053	succinate dehydrogenase
NRZ30_18145	COG0584	glycerophosphoryl diester phosphodiesterase
NRZ30_18150	COG1511	domain protein
NRZ30_18150	COG3264	Mechanosensitive ion channel
NRZ30_18160	COG0739	heme binding
NRZ30_18170	COG0583	DNA-binding transcription factor activity
NRZ30_18190	COG0583	DNA-binding transcription factor activity
NRZ30_18195	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
NRZ30_18225	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
NRZ30_18230	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
NRZ30_18240	COG0338	D12 class N6 adenine-specific DNA methyltransferase
NRZ30_18245	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
NRZ30_18255	COG0180	Tryptophanyl-tRNA synthetase
NRZ30_18265	COG0512	Glutamine amidotransferase of anthranilate synthase
NRZ30_18270	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
NRZ30_18280	COG1012	belongs to the aldehyde dehydrogenase family
NRZ30_18295	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
NRZ30_18305	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
NRZ30_18305	COG0674	pyruvate-flavodoxin oxidoreductase activity
NRZ30_18305	COG1013	pyruvate-flavodoxin oxidoreductase activity
NRZ30_18305	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
NRZ30_18310	COG0366	Alpha amylase catalytic
NRZ30_18330	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
NRZ30_18340	COG0471	metal ion transport
NRZ30_18340	COG0490	domain, Protein
NRZ30_18370	COG0583	DNA-binding transcription factor activity
NRZ30_18375	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
NRZ30_18380	COG3842	ATPase activity
NRZ30_18385	COG1176	ABC-type spermidine putrescine transport system, permease component I
NRZ30_18390	COG1177	transmembrane transport
NRZ30_18395	COG1012	belongs to the aldehyde dehydrogenase family
NRZ30_18400	COG0012	GTP binding
NRZ30_18405	COG0193	aminoacyl-tRNA hydrolase activity
NRZ30_18410	COG0737	Belongs to the 5'-nucleotidase family
NRZ30_18415	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
NRZ30_18425	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
NRZ30_18430	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
NRZ30_18435	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
NRZ30_18440	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
NRZ30_18445	COG2890	protein-(glutamine-N5) methyltransferase activity
NRZ30_18455	COG2912	Transglutaminase-like superfamily
NRZ30_18460	COG2877	3-deoxy-8-phosphooctulonate synthase activity
NRZ30_18465	COG1301	dicarboxylic acid transport
NRZ30_18480	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
NRZ30_18490	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
NRZ30_18490	COG3408	Glycogen debranching enzyme
NRZ30_18500	COG1881	PFAM PEBP family protein
NRZ30_18505	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
NRZ30_18520	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
NRZ30_18530	COG0583	DNA-binding transcription factor activity
NRZ30_18535	COG1028	Short-chain dehydrogenase reductase Sdr
NRZ30_18540	COG0616	signal peptide processing
NRZ30_18545	COG2211	Major facilitator Superfamily
NRZ30_18550	COG3706	GGDEF domain
NRZ30_18555	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
NRZ30_18565	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
NRZ30_18570	COG0826	peptidase U32
NRZ30_18575	COG2200	EAL domain
NRZ30_18575	COG2199	diguanylate cyclase activity
NRZ30_18575	COG2203	Gaf domain
NRZ30_18600	COG2197	response regulator
NRZ30_18605	COG0784	Response regulator, receiver
NRZ30_18605	COG2205	protein histidine kinase activity
NRZ30_18605	COG5002	protein histidine kinase activity
NRZ30_18630	COG3724	N-succinylarginine dihydrolase activity
NRZ30_18655	COG2971	BadF BadG BcrA BcrD
NRZ30_18665	COG4608	Belongs to the ABC transporter superfamily
NRZ30_18670	COG0444	Belongs to the ABC transporter superfamily
NRZ30_18675	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
NRZ30_18680	COG0601	transmembrane transport
NRZ30_18685	COG4166	transmembrane transport
NRZ30_18690	COG2205	protein histidine kinase activity
NRZ30_18690	COG0784	Response regulator, receiver
NRZ30_18735	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
NRZ30_18740	COG1289	transmembrane transporter activity
NRZ30_18745	COG0303	'Molybdopterin
NRZ30_18750	COG0746	molybdenum cofactor guanylyltransferase activity
NRZ30_18755	COG1136	(ABC) transporter
NRZ30_18760	COG4662	Binding-protein-dependent transport system inner membrane component
NRZ30_18770	COG2204	response regulator
NRZ30_18775	COG3852	Histidine kinase
NRZ30_18780	COG1910	domain protein
NRZ30_18785	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
NRZ30_18820	COG3383	formate dehydrogenase (NAD+) activity
NRZ30_18820	COG3383	formate dehydrogenase (NAD+) activity
NRZ30_18825	COG0437	4 iron, 4 sulfur cluster binding
NRZ30_18835	COG0745	RESPONSE REGULATOR receiver
NRZ30_18840	COG0281	malic enzyme
NRZ30_18855	COG2233	PERMEase
NRZ30_18860	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
NRZ30_18895	COG1737	Transcriptional regulator
NRZ30_18900	COG0469	pyruvate kinase activity
NRZ30_18910	COG1677	Flagellar hook-basal body complex protein FliE
NRZ30_18920	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
NRZ30_18975	COG1684	flagellar biosynthetic protein fliR
NRZ30_18985	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
NRZ30_19010	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
NRZ30_19015	COG0643	Histidine kinase
NRZ30_19015	COG2198	Histidine kinase
NRZ30_19015	COG0784	Response regulator, receiver
NRZ30_19020	COG2201	protein-glutamate methylesterase activity
NRZ30_19025	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
NRZ30_19030	COG1360	Flagellar Motor Protein
NRZ30_19035	COG1192	Involved in chromosome partitioning
NRZ30_19045	COG0835	chemotaxis
NRZ30_19060	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
NRZ30_19065	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
NRZ30_19070	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
NRZ30_19075	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
NRZ30_19080	COG1138	Cytochrome C-type biogenesis protein
NRZ30_19085	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
NRZ30_19110	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
NRZ30_19115	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
NRZ30_19125	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
NRZ30_19130	COG1882	Formate acetyltransferase
NRZ30_19140	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
NRZ30_19140	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
NRZ30_19145	COG0259	pyridoxamine-phosphate oxidase activity
NRZ30_19150	COG0625	glutathione transferase activity
NRZ30_19170	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
NRZ30_19180	COG1397	ADP-ribosylglycohydrolase
NRZ30_19190	COG2850	peptidyl-arginine hydroxylation
NRZ30_19195	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
NRZ30_19200	COG2915	High frequency lysogenization protein hflD homolog
NRZ30_19205	COG0482	sulfurtransferase activity
NRZ30_19210	COG1051	belongs to the nudix hydrolase family
NRZ30_19215	COG1187	pseudouridine synthase activity
NRZ30_19225	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
NRZ30_19235	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
NRZ30_19235	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
NRZ30_19235	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
NRZ30_19250	COG4821	SIS domain
NRZ30_19260	COG1609	Transcriptional regulator
NRZ30_19265	COG1263	PTS System
NRZ30_19265	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
NRZ30_19270	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
NRZ30_19285	COG4792	protein secretion
NRZ30_19290	COG4791	protein targeting
NRZ30_19295	COG4794	Type iii secretion
NRZ30_19300	COG4790	Type iii secretion
NRZ30_19370	COG0457	Tetratricopeptide repeat
NRZ30_19460	COG1317	bacterial-type flagellum organization
NRZ30_19475	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
NRZ30_19480	COG1960	acyl-CoA dehydrogenase activity
NRZ30_19490	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
NRZ30_19500	COG3383	formate dehydrogenase (NAD+) activity
NRZ30_19565	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
NRZ30_19570	COG2867	negative regulation of translational initiation
NRZ30_19575	COG2914	Belongs to the UPF0125 (RnfH) family
NRZ30_19580	COG1473	amidohydrolase
NRZ30_19585	COG1960	acyl-CoA dehydrogenase activity
NRZ30_19590	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
NRZ30_19595	COG0121	glutamine amidotransferase
NRZ30_19625	COG2197	response regulator
NRZ30_19630	COG3850	Histidine kinase
NRZ30_19635	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
NRZ30_19640	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
NRZ30_19650	COG0243	molybdopterin cofactor binding
NRZ30_19655	COG0437	4 iron, 4 sulfur cluster binding
NRZ30_19660	COG0348	domain, Protein
NRZ30_19670	COG3005	denitrification pathway
NRZ30_19675	COG0521	Mo-molybdopterin cofactor biosynthetic process
NRZ30_19680	COG0315	cyclic pyranopterin monophosphate synthase activity
NRZ30_19685	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
NRZ30_19690	COG0314	molybdopterin synthase activity
NRZ30_19705	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
NRZ30_19725	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
NRZ30_19730	COG0303	'Molybdopterin
NRZ30_19735	COG0302	gtp cyclohydrolase
NRZ30_19740	COG0840	transmembrane signaling receptor activity
NRZ30_19745	COG2759	Belongs to the formate--tetrahydrofolate ligase family
NRZ30_19755	COG0583	DNA-binding transcription factor activity
NRZ30_19785	COG2195	Cleaves the N-terminal amino acid of tripeptides
NRZ30_19790	COG1166	arginine decarboxylase activity
NRZ30_19800	COG2015	COG2015, Alkyl sulfatase and related hydrolases
NRZ30_19810	COG0583	DNA-binding transcription factor activity
NRZ30_19830	COG0814	amino acid
NRZ30_19840	COG3681	Belongs to the UPF0597 family
NRZ30_19845	COG2964	Protein conserved in bacteria
NRZ30_19850	COG0406	alpha-ribazole phosphatase activity
NRZ30_19860	COG1879	ABC-type sugar transport system periplasmic component
NRZ30_19865	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
NRZ30_19870	COG1288	antiporter activity
NRZ30_19875	COG0436	Aminotransferase
NRZ30_19885	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
NRZ30_19890	COG0741	lytic transglycosylase activity
NRZ30_19890	COG0739	heme binding
NRZ30_19890	COG1196	nuclear chromosome segregation
NRZ30_19915	COG0788	formyltetrahydrofolate deformylase activity
NRZ30_19920	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
NRZ30_19930	COG3118	belongs to the thioredoxin family
NRZ30_19940	COG0791	NLP P60 protein
NRZ30_19945	COG3129	Specifically methylates the adenine in position 1618 of 23S rRNA
NRZ30_19955	COG0471	metal ion transport
NRZ30_19965	COG1376	ErfK ybiS ycfS ynhG family protein
NRZ30_19965	COG1388	LysM domain
NRZ30_20040	COG2877	3-deoxy-8-phosphooctulonate synthase activity
NRZ30_20045	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
NRZ30_20090	COG3038	cytochrome b561
NRZ30_20135	COG2003	Belongs to the UPF0758 family
NRZ30_20185	COG3311	Transcriptional regulator
NRZ30_20195	COG2916	Histone family protein nucleoid-structuring protein H-NS
NRZ30_20200	COG0582	viral genome integration into host DNA
NRZ30_20225	COG1388	LysM domain
NRZ30_20225	COG0741	lytic transglycosylase activity
NRZ30_20230	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
NRZ30_20235	COG2226	methyltransferase
NRZ30_20240	COG0328	RNA-DNA hybrid ribonuclease activity
NRZ30_20245	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
NRZ30_20255	COG0784	Response regulator, receiver
NRZ30_20255	COG3437	response regulator, receiver
NRZ30_20260	COG2375	cellular response to nickel ion
NRZ30_20265	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NRZ30_20270	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NRZ30_20275	COG1120	ATPase activity
NRZ30_20280	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
NRZ30_20290	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
NRZ30_20295	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NRZ30_20315	COG0708	Exodeoxyribonuclease III
NRZ30_20345	COG3132	Protein of unknown function, DUF480
NRZ30_20350	COG2841	Protein conserved in bacteria
NRZ30_20360	COG0534	Mate efflux family protein
NRZ30_20380	COG1454	alcohol dehydrogenase
NRZ30_20390	COG1309	transcriptional regulator
NRZ30_20425	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
NRZ30_20430	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
NRZ30_20435	COG1845	cytochrome c oxidase, subunit III
NRZ30_20440	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
NRZ30_20445	COG0109	protoheme IX farnesyltransferase activity
NRZ30_20450	COG2814	Major facilitator Superfamily
NRZ30_20455	COG3152	Membrane
NRZ30_20460	COG2175	clavaminate synthase activity
NRZ30_20465	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
NRZ30_20470	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
NRZ30_20475	COG4521	taurine ABC transporter
NRZ30_20490	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
NRZ30_20500	COG0840	transmembrane signaling receptor activity
NRZ30_20510	COG1482	cell wall glycoprotein biosynthetic process
NRZ30_20515	COG2207	Transcriptional regulator
NRZ30_20520	COG0538	isocitrate dehydrogenase activity
NRZ30_20530	COG0791	NLP P60 protein
NRZ30_20535	COG0583	DNA-binding transcription factor activity
NRZ30_20540	COG0450	alkyl hydroperoxide reductase
NRZ30_20560	COG0500	methyltransferase
NRZ30_20565	COG4106	trans-aconitate 2-methyltransferase activity
NRZ30_20570	COG1801	Protein of unknown function DUF72
NRZ30_20580	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
NRZ30_20585	COG0217	transcriptional regulatory protein
NRZ30_20590	COG1454	alcohol dehydrogenase
NRZ30_20590	COG1012	belongs to the aldehyde dehydrogenase family
NRZ30_20595	COG2095	MarC family integral membrane protein
NRZ30_20605	COG0601	transmembrane transport
NRZ30_20610	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
NRZ30_20625	COG0861	Integral membrane protein TerC family
NRZ30_20630	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
NRZ30_20635	COG2020	methyltransferase activity
NRZ30_20655	COG4139	cobalamin transport
NRZ30_20660	COG4138	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system
NRZ30_20665	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
NRZ30_20670	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
NRZ30_20675	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
NRZ30_20680	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
NRZ30_20685	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
NRZ30_20695	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
NRZ30_20700	COG0505	Belongs to the CarA family
NRZ30_20705	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
NRZ30_20720	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
NRZ30_20735	COG0346	lactoylglutathione lyase activity
NRZ30_20740	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
NRZ30_20745	COG4660	Part of a membrane complex involved in electron transport
NRZ30_20750	COG4659	FMN binding
NRZ30_20755	COG4658	electron transport chain
NRZ30_20765	COG2878	Part of a membrane complex involved in electron transport
NRZ30_20770	COG4657	Part of a membrane complex involved in electron transport
NRZ30_20775	COG1061	Type III restriction enzyme res subunit
NRZ30_20780	COG0346	lactoylglutathione lyase activity
NRZ30_20785	COG1187	pseudouridine synthase activity
NRZ30_20790	COG2807	transmembrane transport
NRZ30_20815	COG2979	Protein of unknown function (DUF533)
NRZ30_20820	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
NRZ30_20830	COG1294	oxidase, subunit
NRZ30_20850	COG3220	belongs to the UPF0276 family
NRZ30_20865	COG2814	Major facilitator Superfamily
NRZ30_20870	COG0656	L-ascorbic acid biosynthetic process
NRZ30_20890	COG0583	DNA-binding transcription factor activity
NRZ30_20900	COG0840	transmembrane signaling receptor activity
NRZ30_20905	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
NRZ30_20910	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
NRZ30_20915	COG2271	Major facilitator Superfamily
NRZ30_20920	COG1349	DNA-binding transcription factor activity
NRZ30_20930	COG0584	glycerophosphoryl diester phosphodiesterase
NRZ30_20935	COG4574	serine-type endopeptidase inhibitor activity
NRZ30_20940	COG3085	chromosome segregation
NRZ30_20945	COG0583	DNA-binding transcription factor activity
NRZ30_20955	COG1448	Aminotransferase
NRZ30_20970	COG0658	competence protein
NRZ30_20970	COG2333	competence protein COMEC
NRZ30_20980	COG1663	tetraacyldisaccharide 4'-kinase activity
NRZ30_20985	COG2835	tetraacyldisaccharide 4'-kinase activity
NRZ30_20990	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
NRZ30_20995	COG2197	response regulator
NRZ30_21000	COG0322	excinuclease ABC activity
NRZ30_21110	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters