locus-tag	class	description
GWI30_00005	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
GWI30_00010	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
GWI30_00015	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
GWI30_00020	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
GWI30_00030	ENOG4105D29	Helix-turn-helix type 11 domain protein
GWI30_00035	ENOG4105ECQ	AraC Family Transcriptional Regulator
GWI30_00040	ENOG4105IGJ	Zn-dependent Hydrolase of the beta-lactamase fold protein
GWI30_00045	ENOG4108ZNX	Heat shock protein
GWI30_00050	ENOG4108ZNX	Heat shock protein
GWI30_00055	ENOG4105JKW	Valine--pyruvate aminotransferase
GWI30_00070	ENOG4105C2C	drug resistance transporter, Bcr CflA
GWI30_00075	ENOG4105EEX	Two component transcriptional regulator (Winged helix family
GWI30_00080	ENOG4105C08	Histidine kinase
GWI30_00085	ENOG4108R80	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions. The C subunit may be involved in assembly of the KDP complex (By similarity)
GWI30_00090	ENOG4105C8X	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity)
GWI30_00095	ENOG4105D9K	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity)
GWI30_00105	ENOG4105KVH	Transcriptional regulator
GWI30_00110	ENOG41074FZ	May increase the rate of spontaneous hydrolysis of aminoacrylate to malonic semialdehyde. Required to remove a toxic intermediate produce in the pyrimidine nitrogen degradation (By similarity)
GWI30_00115	ENOG4105CB2	alcohol dehydrogenase
GWI30_00125	ENOG4105DC8	reductase
GWI30_00130	ENOG4105BZU	Histidine kinase
GWI30_00135	ENOG4105BZS	acriflavin resistance protein
GWI30_00140	ENOG410624X	efflux transporter, rnd family, mfp subunit
GWI30_00145	ENOG4105Y7M	Transcriptional regulator, TetR family
GWI30_00175	ENOG4105DQF	Hydrolase
GWI30_00180	ENOG4108EUD	Lysophospholipase
GWI30_00185	ENOG4105FE8	tRNA (Guanosine-2'-O-)-methyltransferase
GWI30_00195	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
GWI30_00200	ENOG4105VFG	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity)
GWI30_00205	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
GWI30_00210	ENOG4105DKP	glycosyl transferase, family 9
GWI30_00215	ENOG4108W7E	Catalyzes the ATP-dependent phosphorylation of the 3- deoxy-D-manno-octulosonic acid (Kdo) residue in Kdo-lipid IV(A) at the 4-OH position (By similarity)
GWI30_00225	ENOG4105EMK	carboxylate amino acid amine transporter
GWI30_00255	ENOG4108M6U	Universal stress protein A
GWI30_00260	ENOG4105RKW	reductase (By
GWI30_00265	ENOG4105BZU	Histidine kinase
GWI30_00270	ENOG41090A1	ferritin
GWI30_00275	ENOG4105CBX	hi0933 family
GWI30_00280	ENOG4105EU0	Major facilitator Superfamily
GWI30_00300	ENOG4105F2I	Transposase
GWI30_00325	ENOG4108HRK	Histidine kinase
GWI30_00330	ENOG4105DY9	regulatoR
GWI30_00335	ENOG4105FCD	Major Facilitator
GWI30_00340	ENOG4105CY8	phosphoribosylaminoimidazole carboxylase atpase subunit
GWI30_00345	ENOG4108UM6	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity)
GWI30_00350	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
GWI30_00355	ENOG4105F03	Provides the (R)-glutamate required for cell wall biosynthesis (By similarity)
GWI30_00390	ENOG4105CUZ	uba thif-type nad fad binding protein
GWI30_00395	ENOG4105P9C	Participates in cysteine desulfuration mediated by SufS. Cysteine desulfuration mobilizes sulfur from L-cysteine to yield L-alanine and constitutes an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules. Functions as a sulfur acceptor for SufS, by mediating the direct transfer of the sulfur atom from the S-sulfanylcysteine of SufS, an intermediate product of cysteine desulfuration process (By similarity)
GWI30_00400	ENOG4105C9B	Cysteine desulfurase
GWI30_00405	ENOG4105C4R	Atp-dependent dna helicase
GWI30_00410	ENOG4105BZU	Histidine kinase
GWI30_00420	ENOG4105CPQ	Dehydrogenase
GWI30_00425	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
GWI30_00430	ENOG41062JF	Transcriptional regulator
GWI30_00435	ENOG4105CUI	Catalyzes the interconversion between ADP-D-glycero- beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose (By similarity)
GWI30_00440	ENOG4105E2K	Glycosyl transferase (Group 1
GWI30_00445	ENOG4105PF3	O-Antigen polymerase
GWI30_00460	ENOG410600T	transposase
GWI30_00485	ENOG4105D3Z	quinone oxidoreductase, yhdh yhfp family
GWI30_00500	ENOG4105X6C	Flagellar basal body-associated protein FliL
GWI30_00505	ENOG4105VEI	Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4- hydroxybenzoate (4HB) for the ubiquinone pathway (By similarity)
GWI30_00510	ENOG4105C4G	Synthesis of 3-octaprenyl-4-hydroxybenzoate (By similarity)
GWI30_00520	ENOG4105E55	glycerol-3-phosphate acyltransferase
GWI30_00525	ENOG4105DS7	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity)
GWI30_00540	ENOG4107R73	Mate efflux family protein
GWI30_00545	ENOG4108UIQ	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity)
GWI30_00550	ENOG4105E0F	Histidine kinase
GWI30_00555	ENOG4105E3W	Two component transcriptional regulator (Winged helix family
GWI30_00565	ENOG4105D7W	serine acetyltransferase
GWI30_00575	ENOG41065UX	Non-essential, abundant cell division factor that is required for proper Z-ring formation. It is recruited early to the divisome by direct interaction with FtsZ, stimulating Z-ring assembly and thereby promoting cell division earlier in the cell cycle. Its recruitment to the Z-ring requires functional FtsA or ZipA (By similarity)
GWI30_00580	ENOG4108556	Isoprenoid biosynthesis protein with amidotransferase-like domain
GWI30_00585	ENOG4105C2M	dna polymerase I
GWI30_00590	ENOG4108Z0R	Transferase
GWI30_00625	ENOG4105CQ4	Transcriptional regulator
GWI30_00630	ENOG4105D70	Integrase catalytic subunit
GWI30_00635	ENOG4105F5W	AtP-binding protein
GWI30_00640	ENOG4105CNT	hydrolase family 2
GWI30_00645	ENOG4105FK9	beta-D-galactosidase beta subunit
GWI30_00650	ENOG4105E5D	amino acid
GWI30_00655	ENOG4108Y51	tRNA-binding protein
GWI30_00660	ENOG4105E5D	amino acid
GWI30_00665	ENOG4105DHU	Bile acid
GWI30_00670	ENOG4105E46	N-alpha,N-alpha,N-alpha-trimethyl-L-histidine metabolic process
GWI30_00690	ENOG4105CC0	LysR family Transcriptional regulator
GWI30_00705	ENOG4105UIB	(ABC) transporter
GWI30_00710	ENOG4108JQ9	ABC transporter
GWI30_00715	ENOG4105DIH	basic membrane
GWI30_00720	ENOG4105C4R	Atp-dependent dna helicase
GWI30_00725	ENOG4105F2I	Transposase
GWI30_00730	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
GWI30_00740	ENOG41061EV	selenium-binding protein YdfZ
GWI30_00760	ENOG4108YH8	Covalently attaches a chromophore to Cys residue(s) of phycobiliproteins (By similarity)
GWI30_00765	ENOG4105CUC	YeeE YedE family protein
GWI30_00770	ENOG4105CCF	Lysine exporter protein (Lyse ygga)
GWI30_00775	ENOG4105ECQ	AraC Family Transcriptional Regulator
GWI30_00780	ENOG4105FR1	rard protein
GWI30_00790	ENOG4105C26	Dehydrogenase
GWI30_00795	ENOG4108JCI	Transcriptional regulator
GWI30_00805	ENOG4105C26	Dehydrogenase
GWI30_00810	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
GWI30_00815	ENOG4107R11	Transcriptional regulator
GWI30_00820	ENOG4108TFM	Kinase, PfkB family
GWI30_00840	ENOG4105CGY	Dna recombination protein
GWI30_00845	ENOG4105D37	Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA (By similarity)
GWI30_00850	ENOG4105C1A	potassium transporter peripheral membrane
GWI30_00855	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
GWI30_00860	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
GWI30_00865	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
GWI30_00875	ENOG4105C79	DNA protecting protein DprA
GWI30_00880	ENOG4108RPN	Protein smg homolog
GWI30_00885	ENOG4108WI1	Dna topoisomerase
GWI30_00890	ENOG4105EK0	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
GWI30_00895	ENOG4105DBS	Key enzyme in heme biosynthesis. Catalyzes the oxidative decarboxylation of propionic acid side chains of rings A and B of coproporphyrinogen III (By similarity)
GWI30_00900	ENOG4105E2X	shikimate dehydrogenase
GWI30_00905	ENOG4105WHM	Necessary for normal cell division and for the maintenance of normal septation (By similarity)
GWI30_00910	ENOG4106RE7	Cytochrome
GWI30_00915	ENOG4105ZR3	A GTPase-activating protein (GAP) that modifies Der EngA GTPase function. May play a role in ribosome biogenesis (By similarity)
GWI30_00920	ENOG4105XCT	Protein of unknown function (DUF2489)
GWI30_00925	ENOG4105D4P	Coproporphyrinogen iii oxidase
GWI30_00930	ENOG4105EKD	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism (By similarity)
GWI30_00935	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
GWI30_00940	ENOG4105CUX	Signal transduction histidine kinase
GWI30_00950	ENOG4105C5F	glutamine synthetase
GWI30_00955	ENOG4105CI3	gtp-binding protein typa
GWI30_00960	ENOG4107S2Z	UPF0761 membrane protein
GWI30_00965	ENOG4108YYA	Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine (By similarity)
GWI30_00975	ENOG4105SUU	thioesterase domain
GWI30_00985	ENOG4105CB5	ATP-dependent DNA helicase recG
GWI30_00990	ENOG4105JIM	Phosphatidylserine synthase
GWI30_00995	ENOG4105C6Z	Gluconate
GWI30_01000	ENOG4108Z67	carbohydrate kinase, thermoresistant glucokinase family
GWI30_01005	ENOG4105C01	Dihydroxy-acid dehydratase
GWI30_01010	ENOG4108UHU	Aldolase
GWI30_01015	ENOG4105DIQ	Transcriptional regulator
GWI30_01025	ENOG41063SB	peptidase
GWI30_01030	ENOG4105CJI	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
GWI30_01035	ENOG4107YZP	Rhodanese domain protein
GWI30_01040	ENOG4105IX2	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA (By similarity)
GWI30_01045	ENOG4105CSF	NADPH-dependent glycerol-3-phosphate dehydrogenase
GWI30_01050	ENOG4107RUK	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins (By similarity)
GWI30_01055	ENOG4105MJ2	Competence protein
GWI30_01060	ENOG4105D3C	The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters (By similarity)
GWI30_01075	ENOG4105BZM	domain protein
GWI30_01080	ENOG4108RRZ	Transcription elongation factor GreB
GWI30_01090	ENOG4105E0F	Histidine kinase
GWI30_01100	ENOG4108Z10	Involved in the binding of tRNA to the ribosomes (By similarity)
GWI30_01105	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
GWI30_01110	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
GWI30_01115	ENOG41080KG	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
GWI30_01120	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
GWI30_01125	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
GWI30_01130	ENOG4105KAP	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity)
GWI30_01135	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
GWI30_01140	ENOG4108R70	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity)
GWI30_01145	ENOG41083MP	50s ribosomal protein l29
GWI30_01150	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
GWI30_01155	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
GWI30_01160	ENOG4105KAR	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity)
GWI30_01165	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
GWI30_01170	ENOG4105VBI	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
GWI30_01175	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
GWI30_01180	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
GWI30_01185	ENOG4105K4C	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity)
GWI30_01190	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
GWI30_01195	ENOG4105VPB	50S ribosomal protein L30
GWI30_01200	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
GWI30_01205	ENOG4105CGG	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity)
GWI30_01210	ENOG41067V7	50S ribosomal protein L36
GWI30_01215	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
GWI30_01220	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
GWI30_01225	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
GWI30_01230	ENOG4105CTF	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
GWI30_01235	ENOG4108ZT0	50S ribosomal protein l17
GWI30_01275	ENOG4108CAF	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway (By similarity)
GWI30_01280	ENOG4105C7N	Xanthine uracil vitamin C permease
GWI30_01290	ENOG4105CMT	Dihydroxyacetone kinase
GWI30_01295	ENOG4108UTZ	Dihydroxyacetone kinase
GWI30_01305	ENOG4108JU9	GAF modulated sigma54 specific transcriptional regulator Fis family
GWI30_01315	ENOG4105IPI	Membrane
GWI30_01340	ENOG4105CH6	catalase
GWI30_01345	ENOG4108RTV	Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol (By similarity)
GWI30_01350	ENOG4105CF7	AraC family transcriptional regulator
GWI30_01375	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
GWI30_01410	ENOG4105CWB	LysR family transcriptional Regulator
GWI30_01420	ENOG4105C2I	pirin domain protein
GWI30_01425	ENOG4108VBZ	doxx family
GWI30_01430	ENOG4105DSY	exodeoxyribonuclease V, gamma
GWI30_01435	ENOG4107QKA	exodeoxyribonuclease V beta
GWI30_01440	ENOG4107QYX	exodeoxyribonuclease v alpha
GWI30_01445	ENOG4105F2I	Transposase
GWI30_01450	ENOG4105KHA	Glyoxalase Bleomycin resistance protein (Dioxygenase
GWI30_01465	ENOG4108YZA	Nitrogen regulatory protein pii
GWI30_01470	ENOG4105BZU	Histidine kinase
GWI30_01495	ENOG4105E0F	Histidine kinase
GWI30_01500	ENOG4105VEQ	Cold shock protein
GWI30_01520	ENOG4108UUM	single-stranded DNA-binding protein
GWI30_01525	ENOG41086KC	Transcriptional regulator
GWI30_01530	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
GWI30_01535	ENOG4105F2I	Transposase
GWI30_01540	ENOG4105EIF	outer membrane protein W
GWI30_01560	ENOG4105SYT	Methylenetetrahydrofolate reductase
GWI30_01565	ENOG4105E0M	Sulfatase
GWI30_01595	ENOG4105EMU	Dehydrogenase
GWI30_01610	ENOG4108I6A	alcohol dehydrogenase
GWI30_01620	ENOG4108IQK	o-acetylhomoserine
GWI30_01650	ENOG4107IFA	Lipase (EC 3.1.1.3)
GWI30_01660	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
GWI30_01665	ENOG4108UB4	uncharacterized protein ygjQ
GWI30_01675	ENOG4105CEY	Amp-dependent synthetase and ligase
GWI30_01680	ENOG4105DNI	Converts SHCHC to OSB (By similarity)
GWI30_01685	ENOG4108IPT	Naphthoate synthase
GWI30_01690	ENOG4107J5P	Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC). Is also able to catalyze the hydrolysis of the thioester bond in palmitoyl-CoA in vitro (By similarity)
GWI30_01695	ENOG4105C4A	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC) (By similarity)
GWI30_01700	ENOG4105E4F	Isochorismate synthase
GWI30_01705	ENOG4105EIS	1,4-dihydroxy-2-naphthoate octaprenyltransferase
GWI30_01730	ENOG4105C1J	atp-dependent rna helicase
GWI30_01740	ENOG4105D9N	nucleoside
GWI30_01755	ENOG4108UPT	UPF0178 protein
GWI30_01780	ENOG4105E61	Mannitol repressor protein
GWI30_01785	ENOG4107SQ3	mannitol-1-phosphate 5-dehydrogenase
GWI30_01790	ENOG4105CTS	PTS system mannitol-specific
GWI30_01795	ENOG4108IEC	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction (By similarity)
GWI30_01800	ENOG4105CXD	Specific inhibitor of chromosomal initiation of replication in vitro. Binds the three 13-mers in the origin (oriC) to block initiation of replication (By similarity)
GWI30_01805	ENOG4105NNS	Autoinducer synthesis protein
GWI30_01810	ENOG4105VJY	transcriptional regulator
GWI30_01815	ENOG4108ZUB	Lysine exporter protein (Lyse ygga)
GWI30_01820	ENOG4107RNS	bifunctional 2',3'-cyclic nucleotide 2'-phosphodiesterase 3'-nucleotidase periplasmic
GWI30_01825	ENOG4105D1S	lipid A biosynthesis
GWI30_01830	ENOG4105DW0	Catalyzes the ADP transfer to D-glycero-D-manno-heptose 1-phosphate, yielding ADP-D,D-heptose (By similarity)
GWI30_01835	ENOG4105DFG	type I secretion outer membrane protein
GWI30_01840	ENOG41087AY	ADP-Ribose pyrophosphatase
GWI30_01845	ENOG4108SX3	cytoplasmic protein
GWI30_01850	ENOG41070EG	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes (By similarity)
GWI30_01855	ENOG4105IPS	esterase
GWI30_01870	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
GWI30_01875	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
GWI30_01890	ENOG4105F2I	Transposase
GWI30_01915	ENOG4105KD7	acetyltransferase
GWI30_01950	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
GWI30_01960	ENOG4105N2G	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
GWI30_01980	ENOG4107S7E	1-acyl-sn-glycerol-3-phosphate acyltransferase
GWI30_01985	ENOG41087YS	Phage shock protein A
GWI30_02005	ENOG41082IR	Excinuclease ABC C subunit domain protein
GWI30_02015	ENOG4108RG0	uracil-dna glycosylase
GWI30_02025	ENOG4105ETT	transcriptional Regulator, LysR family
GWI30_02030	ENOG4105FAV	ABC, transporter
GWI30_02035	ENOG4105FDK	ABC transporter
GWI30_02040	ENOG4105NXV	High-affinity zinc uptake system protein
GWI30_02060	ENOG4105DR5	peptidase
GWI30_02070	ENOG4105R2J	Conserved Protein
GWI30_02090	ENOG4105D86	that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity)
GWI30_02100	ENOG4107TH8	cina domain protein
GWI30_02105	ENOG4105C68	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity)
GWI30_02120	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
GWI30_02125	ENOG4105CFH	Aspartokinase
GWI30_02130	ENOG4105VM8	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding (By similarity)
GWI30_02165	ENOG41061WM	D-Alanyl-D-Alanine
GWI30_02170	ENOG4106W5V	Membrane
GWI30_02185	ENOG4105MYG	DNA polymerase iii, chi subunit
GWI30_02190	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
GWI30_02195	ENOG4108M8S	permease YjgP YjgQ family protein
GWI30_02200	ENOG4108K5H	permease YjgP YjgQ family protein
GWI30_02220	ENOG4105BZU	Histidine kinase
GWI30_02225	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
GWI30_02245	ENOG4105EYA	deoxyribonuclease
GWI30_02250	ENOG4105D9N	nucleoside
GWI30_02260	ENOG4105FCI	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate (By similarity)
GWI30_02265	ENOG4105CMW	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis (By similarity)
GWI30_02270	ENOG4105CZG	Phosphotransfer between the C1 and C5 carbon atoms of pentose (By similarity)
GWI30_02285	ENOG4108NST	exported protein
GWI30_02295	ENOG4105EAC	phosphoserine phosphatase
GWI30_02310	ENOG4105DNJ	May play a role in the repair of endogenous alkylation damage (By similarity)
GWI30_02320	ENOG4108ZVW	Anti-RNA polymerase sigma 70 factor
GWI30_02325	ENOG4105K70	DNA-binding protein
GWI30_02340	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
GWI30_02345	ENOG4105MYN	Zinc uptake regulation protein
GWI30_02360	ENOG4105CWM	branched-chain amino acid transport system II carrier protein
GWI30_02365	ENOG4107S47	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC) (By similarity)
GWI30_02370	ENOG4105C1J	atp-dependent rna helicase
GWI30_02375	ENOG4105D1Q	UPF0246 protein
GWI30_02385	ENOG4105CZX	twitching motility protein
GWI30_02390	ENOG4105DFA	alanine racemase domain protein
GWI30_02395	ENOG4105II7	pyrroline-5-carboxylate reductase
GWI30_02400	ENOG4108VIA	integral membrane protein
GWI30_02405	ENOG4105VZ9	UPF0235 protein
GWI30_02425	ENOG4105XTV	UPF0231 protein
GWI30_02430	ENOG4108IXP	Carbohydrate diacid transcriptional activator CdaR
GWI30_02435	ENOG4107QQ0	gntp family
GWI30_02440	ENOG4105BZW	Glycerate kinase
GWI30_02455	ENOG4105HEI	LysR family (Transcriptional regulator
GWI30_02460	ENOG4105D9N	nucleoside
GWI30_02470	ENOG4108YZN	class I peptide chain release factor
GWI30_02475	ENOG4108YZA	Nitrogen regulatory protein pii
GWI30_02480	ENOG4107QKW	extracellular solute-binding protein family 1
GWI30_02495	ENOG4105EZR	dyp-type peroxidase family protein
GWI30_02500	ENOG410682Y	Regulates arginine biosynthesis genes (By similarity)
GWI30_02505	ENOG4105E5Z	arginine transporter ATP-binding subunit
GWI30_02510	ENOG4106PMH	Extracellular solute-binding protein family 3
GWI30_02515	ENOG4105GBT	ABC transporter
GWI30_02520	ENOG4105DMR	ABC, transporter
GWI30_02525	ENOG4105C80	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
GWI30_02530	ENOG4108UV7	flagellar protein motX
GWI30_02535	ENOG4108EGH	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity)
GWI30_02545	ENOG4108JU6	CBS domain protein
GWI30_02550	ENOG4106KVJ	cytochrome C assembly protein
GWI30_02555	ENOG4105CB9	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
GWI30_02560	ENOG4105K5M	30s ribosomal protein S16
GWI30_02565	ENOG4108ZR6	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity)
GWI30_02570	ENOG4105D6X	Specifically methylates guanosine-37 in various tRNAs (By similarity)
GWI30_02575	ENOG4108YY1	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity)
GWI30_02590	ENOG4105EJF	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity)
GWI30_02595	ENOG4108HRM	phosphoenolpyruvate--protein phosphotransferase
GWI30_02600	ENOG4105C3B	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity)
GWI30_02605	ENOG4105C0V	Provides the sole de novo source of dTMP for DNA biosynthesis (By similarity)
GWI30_02615	ENOG4105DRC	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity)
GWI30_02625	ENOG41063Z6	transcriptional regulator, lysR family
GWI30_02630	ENOG41080HT	Transcriptional regulator, arsr family
GWI30_02635	ENOG4105KQV	Binds directly to 16S ribosomal RNA (By similarity)
GWI30_02640	ENOG4105CJR	Integral membrane protein (MviN
GWI30_02645	ENOG4105DTN	riboflavin biosynthesis protein ribF
GWI30_02650	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
GWI30_02655	ENOG4105M02	This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity)
GWI30_02660	ENOG41090X3	Peptidyl-prolyl cis-trans isomerase
GWI30_02665	ENOG4105C48	Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) (By similarity)
GWI30_02685	ENOG410600T	transposase
GWI30_02715	ENOG4105D70	Integrase catalytic subunit
GWI30_02720	ENOG4105F5W	AtP-binding protein
GWI30_02730	ENOG410600T	transposase
GWI30_02735	ENOG4105C4K	Nad synthetase
GWI30_02740	ENOG4108YZA	Nitrogen regulatory protein pii
GWI30_02750	ENOG4106762	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD) (By similarity)
GWI30_02760	ENOG4106TD9	Diguanylate cyclase
GWI30_02765	ENOG4105C40	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity)
GWI30_02780	ENOG4107YB6	acetyltransferase, (GNAT) family
GWI30_02795	ENOG4105C56	H( )-stimulated, divalent metal cation uptake system (By similarity)
GWI30_02800	ENOG4108ZDX	Binds together with S18 to 16S ribosomal RNA (By similarity)
GWI30_02805	ENOG4105VH8	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity)
GWI30_02810	ENOG4105K9Q	Binds to the 23S rRNA (By similarity)
GWI30_02815	ENOG4105DP0	ferredoxin-NADP reductase
GWI30_02825	ENOG4105D5G	Transposase
GWI30_02840	ENOG4105DQ4	alcohol dehydrogenase
GWI30_02845	ENOG4105W39	Membrane
GWI30_02855	ENOG4105D9M	gamma-glutamylcysteine synthetase
GWI30_02860	ENOG4105DS2	Anaerobic c4-dicarboxylate transporter
GWI30_02865	ENOG4108IJ0	Aspartate ammonia-lyase
GWI30_02870	ENOG4108YH1	overproduction of this protein in Escherichia coli inhibits the F plasmid-mediated exclusion of bacteriophage T7
GWI30_02880	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
GWI30_02885	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
GWI30_02895	ENOG4105BZU	Histidine kinase
GWI30_02905	ENOG4105D3G	Pseudouridine synthase
GWI30_02910	ENOG4105BZK	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair (By similarity)
GWI30_02950	ENOG4108I5D	sulfate abc transporter
GWI30_02955	ENOG4105ECW	sulfate abc transporter
GWI30_02960	ENOG4108IJ6	ABC transporter
GWI30_02965	ENOG4107R11	Transcriptional regulator
GWI30_02975	ENOG4108M1A	Chitin-binding protein
GWI30_02980	ENOG4105C8Q	Methyl-accepting chemotaxis
GWI30_03005	ENOG4105G0K	glycine radical enzyme YjjI family
GWI30_03010	ENOG41076CZ	activating enzyme
GWI30_03025	ENOG4105CGF	Aromatic amino acid aminotransferase
GWI30_03050	ENOG4107QZ7	Cellulose synthase catalytic subunit
GWI30_03055	ENOG4107EEX	Cellulose synthase regulator protein
GWI30_03060	ENOG4105K2Z	endo-1,4-d-glucanase (EC 3.2.1.4)
GWI30_03065	ENOG4105EJG	cellulose synthase
GWI30_03090	ENOG410600T	transposase
GWI30_03110	ENOG4108V1J	Has antioxidant activity. Could remove peroxides or H(2)O(2) (By similarity)
GWI30_03115	ENOG4105C1J	atp-dependent rna helicase
GWI30_03130	ENOG4108QYW	Bacterial hemolysins are exotoxins that attack blood cell membranes and cause cell rupture. Beta-hemolysin is a phospholipase C with specific activity toward sphingomyelins. Has a high specificity for sphingomyelin, hydrolyzes lysophosphatidylcholine at a much lower rate, but has no activity towards phosphatidylcholine, phosphatidylethanolamine, or phosphatidylserine (By similarity)
GWI30_03135	ENOG4107RHT	methyl-accepting chemotaxis sensory transducer with Pas Pac sensor
GWI30_03145	ENOG4107QSI	ABC, transporter
GWI30_03155	ENOG4106WH9	Protein of unknown function (DUF2753)
GWI30_03160	ENOG4105E39	Enoyl-CoA hydratase
GWI30_03175	ENOG4108RZ4	Short-chain dehydrogenase reductase Sdr
GWI30_03180	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
GWI30_03185	ENOG4105KA4	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity)
GWI30_03190	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
GWI30_03195	ENOG4105C4M	(Ubiquinol oxidase) subunit I
GWI30_03200	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
GWI30_03210	ENOG4105KJB	cyd operon protein YbgE
GWI30_03215	ENOG4107YD3	Thioesterase
GWI30_03220	ENOG4105E02	MotA TolQ exbB proton channel
GWI30_03225	ENOG4105M8F	Biopolymer transport protein exbD tolR
GWI30_03235	ENOG4107R6Y	Involved in the TonB-independent uptake of proteins (By similarity)
GWI30_03240	ENOG4105KCK	Peptidoglycan-associated lipoprotein
GWI30_03245	ENOG4105UFD	tol-pal system protein YbgF
GWI30_03320	ENOG4105D0I	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate (By similarity)
GWI30_03325	ENOG4105DSB	aldose 1-epimerase
GWI30_03330	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
GWI30_03335	ENOG4107RTM	4-alpha-glucanotransferase (EC 2.4.1.25)
GWI30_03340	ENOG4105C9C	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity)
GWI30_03350	ENOG4105E0X	reductase
GWI30_03365	ENOG4105CJH	Alcohol dehydrogenase zinc-binding domain protein
GWI30_03370	ENOG4105K56	Transcriptional regulator
GWI30_03385	ENOG4105EW9	transcriptional regulator AsnC family
GWI30_03400	ENOG410667J	hydrolase
GWI30_03415	ENOG4105C8J	)-transporter
GWI30_03420	ENOG4105C8J	)-transporter
GWI30_03435	ENOG4107SQD	Transcriptional regulator, GntR family
GWI30_03460	ENOG4108IQE	Amp-dependent synthetase and ligase
GWI30_03470	ENOG41080E2	ribosomal-protein-alanine acetyltransferase
GWI30_03485	ENOG4105EV2	VWA domain protein interacting with AAA ATPase
GWI30_03490	ENOG4105BZU	Histidine kinase
GWI30_03500	ENOG4105C8A	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP (By similarity)
GWI30_03505	ENOG4108MJ3	acetyltransferase
GWI30_03510	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
GWI30_03530	ENOG4105DWY	Agmatine deiminase
GWI30_03535	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
GWI30_03555	ENOG4105C1J	atp-dependent rna helicase
GWI30_03560	ENOG4105FSR	swimming returnes to normal when residues 206-207 are both mutated to Ala. Overexpression also leads to a reduction in flagellar abundance and a 20-fold increase in c-di- GMP levels in vivo. Required for aminoglycoside-mediated induction of biofilm formation, it also plays a lesser role in biofilm production in response to other classes of translation inhibitors. The c-di-GMP produced by this enzyme up-regulates poly-GlcNAc production as well as the biofilm synthesis protein PgaD, although c-di-GMP is probably not the main inducing principle. Cyclic-di- GMP is a second messenger which controls cell surface-associated traits in bacteria
GWI30_03570	ENOG4107V4F	S-adenosyl-l-methionine hydroxide adenosyltransferase
GWI30_03595	ENOG4107QWG	2-Nitropropane dioxygenase
GWI30_03625	ENOG4105D70	Integrase catalytic subunit
GWI30_03630	ENOG4105F5W	AtP-binding protein
GWI30_03645	ENOG4108IAB	Phoh family
GWI30_03655	ENOG4106SMU	thiamine transporter membrane protein
GWI30_03660	ENOG4105DP9	ABC transporter
GWI30_03675	ENOG4105MQS	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
GWI30_03680	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
GWI30_03685	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
GWI30_03690	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
GWI30_03700	ENOG4105YVM	Phosphoesterase, PA-phosphatase related
GWI30_03705	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
GWI30_03715	ENOG4105C7K	acetolactate synthase
GWI30_03720	ENOG4108ZP8	Acetolactate synthase small subunit
GWI30_03725	ENOG4105C6K	Malic enzyme
GWI30_03730	ENOG4105C6H	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity)
GWI30_03740	ENOG4105XWI	UPF0304 protein
GWI30_03745	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
GWI30_03750	ENOG4105RH4	Glycine cleavage system transcriptional repressor
GWI30_03755	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
GWI30_03760	ENOG4107EG0	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
GWI30_03765	ENOG4107QWK	SAICAR synthetase
GWI30_03775	ENOG4105EXG	Transcriptional regulator
GWI30_03800	ENOG4105BZU	Histidine kinase
GWI30_03805	ENOG4105C4Q	deoxyguanosinetriphosphate triphosphohydrolase-like protein
GWI30_03815	ENOG410600T	transposase
GWI30_03825	ENOG4105BZU	Histidine kinase
GWI30_03860	ENOG4105D6S	protein involved in catabolism of external DNA
GWI30_03870	ENOG4105C5H	ABC transporter
GWI30_03875	ENOG41080XP	Cbs domain
GWI30_03895	ENOG4105F2I	Transposase
GWI30_03900	ENOG4105FCK	Membrane
GWI30_03915	ENOG4108UJV	acyl-CoA thioesterase i
GWI30_03920	ENOG4108I0Y	(ABC) transporter
GWI30_03925	ENOG4105CV6	ABC transporter, permease
GWI30_03930	ENOG4105ECP	epimerase
GWI30_03935	ENOG4105BZU	Histidine kinase
GWI30_03940	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
GWI30_03945	ENOG4105IIU	Aminopeptidase
GWI30_03950	ENOG4105CZ1	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity)
GWI30_03955	ENOG41090ED	Protein with unknown function (DUF469)
GWI30_03960	ENOG4105CSV	Glutaminase
GWI30_03965	ENOG4107RM6	sulfurtransferase
GWI30_03970	ENOG4105SUV	lipoprotein YgdR
GWI30_03975	ENOG4105BZ1	(ABC) transporter
GWI30_04020	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
GWI30_04065	ENOG410600T	transposase
GWI30_04125	ENOG4105F2I	Transposase
GWI30_04135	ENOG4105CT4	transporter
GWI30_04145	ENOG4105ETE	Transcriptional regulator (LacI family
GWI30_04150	ENOG4105W3H	MtN3 and saliva related transmembrane protein
GWI30_04155	ENOG4105ENN	converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose (By similarity)
GWI30_04160	ENOG4105CRD	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P) (By similarity)
GWI30_04165	ENOG4105F0Z	galactose-1-phosphate uridylyltransferase
GWI30_04170	ENOG4105CMR	udp-glucose 4-epimerase
GWI30_04180	ENOG4105KQT	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome (By similarity)
GWI30_04190	ENOG4105BZU	Histidine kinase
GWI30_04220	ENOG4105VYA	Uncharacterized conserved protein (DUF2132)
GWI30_04225	ENOG4105DJ4	phosphatidylserine decarboxylase
GWI30_04235	ENOG4108RBP	3'-to-5' exoribonuclease specific for small oligoribonucleotides (By similarity)
GWI30_04275	ENOG4105VEQ	Cold shock protein
GWI30_04285	ENOG4105C8Q	Methyl-accepting chemotaxis
GWI30_04290	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
GWI30_04295	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
GWI30_04350	ENOG4109015	Biopolymer transport protein exbD tolR
GWI30_04375	ENOG410600T	transposase
GWI30_04385	ENOG4108I5X	binding-protein-dependent transport systems inner membrane Component
GWI30_04390	ENOG4108IYQ	Binding-protein-dependent transport systems inner membrane component
GWI30_04395	ENOG4107QRA	Extracellular solute-binding protein, family 5
GWI30_04405	ENOG4108JQ7	(ABC) transporter
GWI30_04415	ENOG4105CIN	aminoacyl-histidine dipeptidase
GWI30_04425	ENOG4105DYA	Acts on guanine, xanthine and to a lesser extent hypoxanthine (By similarity)
GWI30_04430	ENOG4105V1F	Fermentation respiration switch protein
GWI30_04435	ENOG4108UVK	Binds to the sigma-S subunit of RNA polymerase, activating expression of sigma-S-regulated genes. Stimulates RNA polymerase holoenzyme formation and may bind to several other sigma factors, such as sigma-70 and sigma-32 (By similarity)
GWI30_04445	ENOG4105C2S	Catalyzes the NADPH dependent reduction of L-gamma- glutamyl 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate (By similarity)
GWI30_04490	ENOG4105DG7	nitrate ABC transporter
GWI30_04495	ENOG4105D7T	ABC transporter
GWI30_04500	ENOG4107QZF	nitrite reductase NADPH large subunit
GWI30_04505	ENOG4107QZF	nitrite reductase NADPH large subunit
GWI30_04510	ENOG4105DD7	kinase (PfkB family
GWI30_04515	ENOG4105D53	Catalyzes the hydrolysis of pseudouridine 5'-phosphate (PsiMP) to ribose 5-phosphate and uracil (By similarity)
GWI30_04535	ENOG410600T	transposase
GWI30_04570	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
GWI30_04600	ENOG4105C84	Histidine ammonia-lyase
GWI30_04635	ENOG4105C2D	reductase
GWI30_04640	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
GWI30_04650	ENOG4108RIR	Molybdenum cofactor biosynthesis protein
GWI30_04665	ENOG4105DWK	Membrane
GWI30_04670	ENOG4107XM3	UPF0442 protein
GWI30_04680	ENOG4108IJ7	Glycine betaine
GWI30_04685	ENOG4108HQS	Glycine betaine
GWI30_04690	ENOG4105GIJ	Glycine betaine
GWI30_04695	ENOG4105ET3	Reduction of activated sulfate into sulfite (By similarity)
GWI30_04700	ENOG4105ET1	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate (By similarity)
GWI30_04705	ENOG4107EER	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity)
GWI30_04710	ENOG4107TIF	Phenazine biosynthesis protein, PhzF family
GWI30_04715	ENOG4105CRK	lysyL-tRNA synthetase
GWI30_04725	ENOG4105C8Q	Methyl-accepting chemotaxis
GWI30_04745	ENOG4105HDK	L-asparaginase
GWI30_04750	ENOG4105VUT	cytoplasmic protein
GWI30_04770	ENOG4105D07	Signal peptide peptidase, SppA
GWI30_04775	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
GWI30_04780	ENOG41069NU	Nitroreductase
GWI30_04795	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
GWI30_04805	ENOG4105HEI	LysR family (Transcriptional regulator
GWI30_04810	ENOG4105CI1	PTS System
GWI30_04815	ENOG4108IA2	Sodium pantothenate symporter
GWI30_04820	ENOG4105RG0	Membrane
GWI30_04825	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
GWI30_04830	ENOG4105KM4	Acetyl-CoA carboxylase, biotin carboxyl carrier protein
GWI30_04835	ENOG4108Z38	Catalyzes a trans-dehydration via an enolate intermediate (By similarity)
GWI30_04840	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
GWI30_04855	ENOG4109039	Involved in the biogenesis of TorA. Acts on TorA before the insertion of the molybdenum cofactor and, as a result, probably favors a conformation of the apoenzyme that is competent for acquiring the cofactor (By similarity)
GWI30_04860	ENOG4108EM1	reductase
GWI30_04865	ENOG4105CUW	cytochrome C-TYPE protein
GWI30_04870	ENOG4106WF9	DNA-binding transcriptional regulator TorR
GWI30_04880	ENOG4108SV3	Tmao reductase system periplasmic protein tort
GWI30_04885	ENOG4105BZU	Histidine kinase
GWI30_04895	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
GWI30_04910	ENOG4108Z11	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes (By similarity)
GWI30_04915	ENOG4105D1W	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity)
GWI30_04930	ENOG4108UTT	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity)
GWI30_04935	ENOG4107YIM	Involved in the transcription termination process (By similarity)
GWI30_04940	ENOG4105CG2	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity)
GWI30_04945	ENOG4108ZAI	phosphatidylglycerophosphatase a
GWI30_04950	ENOG4108JQ6	ABC transporter
GWI30_04960	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
GWI30_04965	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
GWI30_04970	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
GWI30_04975	ENOG4105CTB	Polyprenyl synthetase
GWI30_04980	ENOG41067QG	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
GWI30_04985	ENOG4105E14	MotA TolQ exbB proton channel
GWI30_04990	ENOG4107XSU	flagellar motor protein motb
GWI30_04995	ENOG4108UKH	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
GWI30_05005	ENOG4105HBR	Rna-binding protein
GWI30_05010	ENOG4105F7M	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit (By similarity)
GWI30_05015	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
GWI30_05020	ENOG4105EEI	dihydropteroate synthase
GWI30_05025	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
GWI30_05030	ENOG4105CP7	Triose-phosphate isomerase
GWI30_05035	ENOG4105NTZ	Preprotein translocase subunit SecG
GWI30_05050	ENOG4105K7D	Required for maturation of 30S ribosomal subunits (By similarity)
GWI30_05055	ENOG4105CHV	Transcription elongation factor NusA
GWI30_05060	ENOG4107QHU	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
GWI30_05065	ENOG4105KG7	Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity)
GWI30_05070	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
GWI30_05075	ENOG4105K77	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity)
GWI30_05080	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
GWI30_05085	ENOG4105E5W	Transporter
GWI30_05090	ENOG41090EX	DsrE family
GWI30_05110	ENOG4105K5D	4fe-4S ferredoxin iroN-sulfur binding
GWI30_05115	ENOG4105CFP	Peptidase U32
GWI30_05120	ENOG4107N1Q	ErfK YbiS YcfS YnhG family protein
GWI30_05135	ENOG4105D1U	peptidase U62 modulator of DNA gyrase
GWI30_05140	ENOG41071R3	Low-potential electron donor to a number of redox enzymes (By similarity)
GWI30_05145	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
GWI30_05155	ENOG4105M2E	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell (By similarity)
GWI30_05170	ENOG4105C2R	Single-stranded-DNA-specific exonuclease (RecJ)
GWI30_05180	ENOG4108IUB	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
GWI30_05195	ENOG4105EQR	Transposase IS116 IS110 IS902
GWI30_05210	ENOG4105C0G	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity)
GWI30_05220	ENOG4108BDP	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity)
GWI30_05225	ENOG4108Z43	UPF0250 protein
GWI30_05230	ENOG4105DZ1	carboxypeptidase
GWI30_05235	ENOG4105K6T	rare lipoprotein A
GWI30_05240	ENOG4105CVE	Lytic murein transglycosylase
GWI30_05245	ENOG4105CNI	cell division protein FtsW
GWI30_05250	ENOG4105CJN	penicillin-binding protein
GWI30_05255	ENOG4108UXA	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA (By similarity)
GWI30_05260	ENOG4105KEM	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation (By similarity)
GWI30_05265	ENOG4108Z1W	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity)
GWI30_05280	ENOG4105C8T	Leucyl-tRNA synthetase
GWI30_05285	ENOG4107PAI	alpha helical protein
GWI30_05290	ENOG4105CE8	Transfers the fatty acyl group on membrane lipoproteins (By similarity)
GWI30_05295	ENOG4108JU5	Magnesium and cobalt efflux protein
GWI30_05300	ENOG4105KGE	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA (By similarity)
GWI30_05305	ENOG4105C9A	Phoh family
GWI30_05310	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
GWI30_05315	ENOG4105EAK	ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family
GWI30_05320	ENOG4105VEQ	Cold shock protein
GWI30_05325	ENOG4105F04	LysR family Transcriptional regulator
GWI30_05335	ENOG4105EVE	HAD-superfamily hydrolase subfamily IA variant 3
GWI30_05360	ENOG4105BZU	Histidine kinase
GWI30_05370	ENOG4105C5I	Dehydrogenase
GWI30_05380	ENOG4108R5S	membrane
GWI30_05385	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
GWI30_05395	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
GWI30_05405	ENOG4105DHQ	Histidine kinase
GWI30_05410	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
GWI30_05420	ENOG4108IXY	short-chain dehydrogenase reductase
GWI30_05440	ENOG4105DA6	Catalyzes the conversion of 5-methoxyuridine (mo5U) to uridine-5-oxyacetic acid (cmo5U) at position 34 in tRNA. May also participate in the methylation of uridine-5-oxyacetic acid (cmo5U) to uridine-5-oxyacetic acid methyl ester (mcmo5U) (By similarity)
GWI30_05445	ENOG4105T0Z	Conserved Protein
GWI30_05450	ENOG4108VP9	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane (By similarity)
GWI30_05455	ENOG4108WJH	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane (By similarity)
GWI30_05460	ENOG4105E33	succinate dehydrogenase
GWI30_05475	ENOG4108QXE	glycerophosphoryl diester phosphodiesterase
GWI30_05480	ENOG4105EGS	Mechanosensitive ion channel
GWI30_05490	ENOG4105DR5	peptidase
GWI30_05500	ENOG4108VEV	chaperone
GWI30_05505	ENOG4105CW0	outer membrane usher protein
GWI30_05510	ENOG4108VEV	chaperone
GWI30_05525	ENOG4105EJC	lysr family transcriptional regulator
GWI30_05540	ENOG4105C5Q	Transcriptional regulator
GWI30_05545	ENOG4108JQC	penicillin-binding protein 1A
GWI30_05575	ENOG4105KHV	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
GWI30_05580	ENOG4105D49	3-dehydroquinate synthase
GWI30_05590	ENOG4105DFE	Dna adenine methylase
GWI30_05595	ENOG4105DJV	ribulose-phosphate 3-epimerase
GWI30_05600	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
GWI30_05605	ENOG4105C31	Tryptophanyl-tRNA synthetase
GWI30_05620	ENOG4105C8Y	Acetylornithine aminotransferase
GWI30_05625	ENOG4105F4X	arginine
GWI30_05630	ENOG4105C26	Dehydrogenase
GWI30_05640	ENOG4107VXZ	Hydrolase
GWI30_05660	ENOG4105N5Z	UPF0267 protein
GWI30_05665	ENOG4107QWE	)-transporter
GWI30_05710	ENOG4105C3G	gtp-binding protein
GWI30_05715	ENOG4108ZPD	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity)
GWI30_05720	ENOG4105CGH	5'-nucleotidase
GWI30_05725	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
GWI30_05735	ENOG4105CTR	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol (By similarity)
GWI30_05740	ENOG4105C1U	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein (By similarity)
GWI30_05745	ENOG4105C7E	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) (By similarity)
GWI30_05750	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
GWI30_05755	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
GWI30_05765	ENOG41063JG	Transcriptional regulator
GWI30_05770	ENOG4105CXR	Phospho-2-dehydro-3-deoxyoctonate aldolase
GWI30_05775	ENOG4105CK2	sodium dicarboxylate symporter
GWI30_05780	ENOG4108VKA	Acts as a radical domain for damaged PFL and possibly other radical proteins (By similarity)
GWI30_05785	ENOG4105D5S	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine (By similarity)
GWI30_05805	ENOG4105CW3	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
GWI30_05810	ENOG4105BZG	amino acid carrier protein
GWI30_05815	ENOG41066YJ	Beta-lactamase
GWI30_05825	ENOG4105G2Y	Transcriptional regulator
GWI30_05830	ENOG4107Y66	Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity)
GWI30_05840	ENOG4105D7Z	glutathione synthase
GWI30_05845	ENOG4105QF0	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity)
GWI30_05855	ENOG4105GPY	SprT protein
GWI30_05860	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
GWI30_05865	ENOG4105CV1	Transketolase (EC 2.2.1.1)
GWI30_05870	ENOG410600T	transposase
GWI30_05920	ENOG4105KME	endoribonuclease L-psp
GWI30_05930	ENOG4105ED7	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling (By similarity)
GWI30_05935	ENOG4105DR5	peptidase
GWI30_05940	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
GWI30_05960	ENOG41074DU	domain protein
GWI30_05965	ENOG4108P2H	Inner membrane protein YjiG
GWI30_05970	ENOG4105DYB	Isoaspartyl dipeptidase
GWI30_05995	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
GWI30_06010	ENOG4105C87	Aminotransferase class I and II
GWI30_06020	ENOG4105C5Q	Transcriptional regulator
GWI30_06025	ENOG4105UBK	short-chain dehydrogenase reductase
GWI30_06030	ENOG4105ERU	peptidase
GWI30_06035	ENOG4105EY2	Catalyzes the hydrolysis of N(2)-succinylarginine into N(2)-succinylornithine, ammonia and CO(2) (By similarity)
GWI30_06040	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
GWI30_06055	ENOG4107RHT	methyl-accepting chemotaxis sensory transducer with Pas Pac sensor
GWI30_06060	ENOG4105E2D	ec 3.2.1.52
GWI30_06065	ENOG4105RD7	BadF BadG BcrA BcrD
GWI30_06075	ENOG4108JQ7	(ABC) transporter
GWI30_06085	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
GWI30_06105	ENOG4105EUK	rtx toxin RtxA
GWI30_06115	ENOG4105CBM	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 (By similarity)
GWI30_06165	ENOG4105EC0	Required for nucleoid occlusion (NO) phenomenon, which prevents Z-ring formation and cell division over the nucleoid. Acts as a DNA-associated cell division inhibitor that binds simultaneously chromosomal DNA and FtsZ, and disrupts the assembly of FtsZ polymers. SlmA-DNA-binding sequences (SBS) are dispersed on non-Ter regions of the chromosome, preventing FtsZ polymerization at these regions (By similarity)
GWI30_06210	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
GWI30_06215	ENOG4105E14	MotA TolQ exbB proton channel
GWI30_06220	ENOG4108SEK	ompa motb domain protein
GWI30_06225	ENOG4107QJE	Chromosome Partitioning Protein
GWI30_06235	ENOG4108V3W	Chemotaxis protein, CheW
GWI30_06250	ENOG4105CA5	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes (By similarity)
GWI30_06255	ENOG41060IM	Heme exporter protein
GWI30_06260	ENOG4105X3C	heme exporter protein
GWI30_06265	ENOG4108ZKK	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH (By similarity)
GWI30_06270	ENOG4105DA4	cytochrome c-type biogenesis protein
GWI30_06275	ENOG4107QX9	Thiol disulfide interChange protein
GWI30_06280	ENOG4105KWW	Biogenesis protein
GWI30_06290	ENOG410903C	(LipO)protein
GWI30_06295	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
GWI30_06300	ENOG4105M2J	Glutaredoxin
GWI30_06320	ENOG4108S7T	Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) (By similarity)
GWI30_06325	ENOG4107R11	Transcriptional regulator
GWI30_06335	ENOG4105VS7	Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue. This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon. When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation (By similarity)
GWI30_06340	ENOG4106FVC	RNA methyltransferase
GWI30_06355	ENOG4105D5I	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate (By similarity)
GWI30_06360	ENOG4105D98	threonine synthase
GWI30_06365	ENOG4108VSZ	Inherit from COG: ketosteroid isomerase-like protein
GWI30_06405	ENOG4105IFJ	Histidine kinase
GWI30_06410	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
GWI30_06415	ENOG4105C1B	dTDP-glucose 4-6-dehydratase
GWI30_06420	ENOG4105DBZ	Dtdp-4-dehydrorhamnose reductase
GWI30_06430	ENOG4108URP	Dtdp-4-dehydrorhamnose 3,5-epimerase
GWI30_06440	ENOG4105EAG	UDP-N-acetylglucosamine 2-epimerase
GWI30_06465	ENOG4105ESV	Glycosyl transferase, family 4
GWI30_06470	ENOG4108KPN	Confers a modal distribution of chain length on the O- antigen component of lipopolysaccharide (LPS). Gives rise to a reduced number of short chain molecules and increases in numbers of longer molecules, with a modal value of 13 (in strain O111 M92) and of 17 (in strain K12)
GWI30_06495	ENOG4105E18	UPF0276 protein
GWI30_06515	ENOG4107SDU	Methyl-accepting chemotaxis
GWI30_06525	ENOG4108ESY	Metal dependent phosphohydrolase
GWI30_06530	ENOG4105FNP	Molybdopterin-guanine dinucleotide biosynthesis protein b
GWI30_06535	ENOG4105C6R	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor (By similarity)
GWI30_06540	ENOG4107R1I	NAD-dependent malic enzyme
GWI30_06545	ENOG4105C2W	permease
GWI30_06575	ENOG410600T	transposase
GWI30_06585	ENOG4105C2J	ABC transporter
GWI30_06590	ENOG4105CNN	ABC, transporter
GWI30_06595	ENOG4105D17	glycoside hydrolase, family 3 domain protein
GWI30_06610	ENOG4105EGS	Mechanosensitive ion channel
GWI30_06615	ENOG4105CA9	Pyruvate kinase
GWI30_06620	ENOG4105EZE	Cupin 4 family protein
GWI30_06625	ENOG4107QTF	adenylosuccinate lyase
GWI30_06630	ENOG41075W9	High frequency lysogenization protein HflD homolog
GWI30_06635	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
GWI30_06645	ENOG4108R99	pseudouridine synthase
GWI30_06655	ENOG4108YRF	PTS System
GWI30_06660	ENOG4105CXY	transporter
GWI30_06665	ENOG4105DM4	PTS System
GWI30_06690	ENOG4107VGF	ig domain protein group 2 domain protein
GWI30_06695	ENOG4105DM4	PTS System
GWI30_06705	ENOG4105P66	Membrane
GWI30_06710	ENOG4105EIP	mannose-6-phosphate isomerase
GWI30_06715	ENOG4106R3P	AraC family transcriptional regulator
GWI30_06720	ENOG4108HMX	isocitrate dehydrogenase (NADP)
GWI30_06730	ENOG4105BZC	d-serine deaminase
GWI30_06740	ENOG4105W8I	Transcriptional regulator
GWI30_06760	ENOG4105Q26	Siderophore-interacting protein
GWI30_06765	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
GWI30_06770	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
GWI30_06775	ENOG4105DJY	efflux transporter, rnd family, mfp subunit
GWI30_06785	ENOG4105E2M	Manganese-dependent inorganic pyrophosphatase
GWI30_06790	ENOG4105C4F	May be involved in recombinational repair of damaged DNA (By similarity)
GWI30_06795	ENOG4105BZU	Histidine kinase
GWI30_06800	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
GWI30_06805	ENOG4105K90	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
GWI30_06810	ENOG4105CFG	Acts as a chaperone (By similarity)
GWI30_06815	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
GWI30_06825	ENOG4105D7K	pfkb domain protein
GWI30_06840	ENOG4105WBN	Transcriptional regulator (LacI family
GWI30_06875	ENOG4105KFG	YeeE YedE family protein
GWI30_06890	ENOG4105BZU	Histidine kinase
GWI30_06895	ENOG4107RMF	Catalyzes both the ATP-dependent activation of exogenously supplied lipoate to lipoyl-AMP and the transfer of the activated lipoyl onto the lipoyl domains of lipoate-dependent enzymes (By similarity)
GWI30_06910	ENOG4105D7V	transposase
GWI30_06930	ENOG4108IJF	Heavy metal efflux pump, CzcA
GWI30_06935	ENOG4105EP1	Efflux transporter rnd family, mfp subunit
GWI30_06945	ENOG4105CGK	Exodeoxyribonuclease III
GWI30_06955	ENOG4108VYJ	response regulator receiver protein
GWI30_06970	ENOG41090JD	Blue (Type 1) copper domain protein
GWI30_06985	ENOG4105NTK	Transcriptional repressor Mpra
GWI30_07000	ENOG4105D7V	transposase
GWI30_07015	ENOG4105CC0	LysR family Transcriptional regulator
GWI30_07025	ENOG4105E2S	oxidase) subunit II
GWI30_07030	ENOG4105BZ9	Cytochrome C oxidase, subunit I
GWI30_07035	ENOG4105CCU	oxidase (Subunit III)
GWI30_07040	ENOG41090KH	cytochrome o ubiquinol oxidase (subunit iv)
GWI30_07045	ENOG4105F1R	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group (By similarity)
GWI30_07050	ENOG4107RDB	Major Facilitator
GWI30_07055	ENOG4105KCV	RNA signal recognition particle 4.5S RNA
GWI30_07070	ENOG4105JQN	Transcriptional regulator
GWI30_07090	ENOG4105CAF	HipA N-terminal domain protein
GWI30_07135	ENOG4105F6H	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate (By similarity)
GWI30_07140	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
GWI30_07145	ENOG4105DK0	Indole-3-glycerol phosphate synthase
GWI30_07150	ENOG4108I0Q	anthranilate phosphoribosyltransferase
GWI30_07155	ENOG4108EFP	Anthranilate synthase component II
GWI30_07160	ENOG4105CRQ	synthase (Component I)
GWI30_07165	ENOG4105DB7	PHP domain protein
GWI30_07170	ENOG4107RTD	sua5 ycio yrdc ywlc family protein
GWI30_07180	ENOG4105K8I	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves (By similarity)
GWI30_07185	ENOG4105FE9	pseudouridine synthase
GWI30_07190	ENOG4105C29	acyl-CoA thioesterase
GWI30_07205	ENOG4108IG5	Transcriptional regulator
GWI30_07210	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
GWI30_07215	ENOG4105BZS	acriflavin resistance protein
GWI30_07220	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
GWI30_07245	ENOG4105D70	Integrase catalytic subunit
GWI30_07250	ENOG4105F5W	AtP-binding protein
GWI30_07270	ENOG4105VUH	addiction module killer protein
GWI30_07310	ENOG4107SSZ	Phosphatase
GWI30_07320	ENOG4107QPN	acyl-Coa dehydrogenase
GWI30_07325	ENOG4105BZS	acriflavin resistance protein
GWI30_07335	ENOG4105CA9	Pyruvate kinase
GWI30_07340	ENOG4106KNT	transcriptional regulator
GWI30_07360	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
GWI30_07380	ENOG4105F2I	Transposase
GWI30_07410	ENOG410600T	transposase
GWI30_07435	ENOG410600T	transposase
GWI30_07440	ENOG4105EAG	UDP-N-acetylglucosamine 2-epimerase
GWI30_07465	ENOG4108RYC	glycosyltransferase
GWI30_07475	ENOG4105DAY	polysaccharide export protein
GWI30_07480	ENOG4107ZF2	Phosphatase
GWI30_07515	ENOG4108RS6	transposase
GWI30_07525	ENOG4108Q9C	Periplasmic Protein
GWI30_07530	ENOG4105E3R	(LipO)protein
GWI30_07545	ENOG4108YXG	UPF0502 protein
GWI30_07555	ENOG4105KR1	Trans-acting protein required for termination of DNA replication. Binds to DNA replication terminator sequences (terA to terF) to prevent the passage of replication forks. The termination efficiency will be affected by the affinity of this protein for the terminator sequence (By similarity)
GWI30_07570	ENOG4107RUY	(E1 component), alpha subunit
GWI30_07575	ENOG4105CPP	Dehydrogenase, E1 component
GWI30_07585	ENOG4105VEQ	Cold shock protein
GWI30_07615	ENOG4108594	Permease of the drug metabolite transporter
GWI30_07635	ENOG4105D7V	transposase
GWI30_07640	ENOG4105CPI	Metal Dependent Phosphohydrolase
GWI30_07645	ENOG4105I08	Pseudouridine synthase
GWI30_07660	ENOG4107QSI	ABC, transporter
GWI30_07665	ENOG4108RE9	Phosphodiesterase
GWI30_07690	ENOG4105BZU	Histidine kinase
GWI30_07695	ENOG4105K88	Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body (By similarity)
GWI30_07700	ENOG4108ZC9	flagellar basal-body rod protein flgc
GWI30_07710	ENOG4105BZE	flagellar hook protein, FlgE
GWI30_07715	ENOG4108KPB	Flagellar basal-body rod protein FlgF
GWI30_07720	ENOG4105CGA	flagellar basal-body rod protein FlgG
GWI30_07725	ENOG4107W7W	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity)
GWI30_07730	ENOG4105D92	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity)
GWI30_07735	ENOG4108ZW7	flagellar rod assembly protein muramidase flgj
GWI30_07780	ENOG4105D7V	transposase
GWI30_07790	ENOG4105C9X	ppx gppa phosphatase
GWI30_07795	ENOG4105CUU	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) (By similarity)
GWI30_07800	ENOG4105RH4	Glycine cleavage system transcriptional repressor
GWI30_07815	ENOG4105BZU	Histidine kinase
GWI30_07825	ENOG4107QNR	UPF0135 protein
GWI30_07830	ENOG4108V3E	phosphoribosylglycinamide formyltransferase
GWI30_07835	ENOG4105CXB	phosphoribosylaminoimidazole synthetase
GWI30_07840	ENOG4105CZ5	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate (By similarity)
GWI30_07850	ENOG4108KZ1	Mediates the interaction of DNA replication inititator protein DnaA with DNA polymerase subunit beta sliding clamp (dnaN). Stimulates hydrolysis of ATP-DnaA to ADP-DnaA, rendering DnaA inactive for reinititation, a process called regulatory inhibition of DnaA or RIDA (By similarity)
GWI30_07860	ENOG4108I9X	Isocitrate lyase
GWI30_07865	ENOG4107QP3	malate synthase g
GWI30_07875	ENOG4108Z6B	deaminase
GWI30_07880	ENOG4105C8U	phosphate abc transporter
GWI30_07885	ENOG4105E2Z	phosphate ABC transporter (Permease
GWI30_07890	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
GWI30_07895	ENOG4108UTW	Plays a role in the regulation of phosphate uptake
GWI30_07900	ENOG4105C37	(CBS) domain
GWI30_07915	ENOG4105D5Q	Arginine ornithine antiporter
GWI30_07920	ENOG4105VNT	transposase (IS4 family) protein
GWI30_07930	ENOG4105CDA	abc transporter atp-binding protein
GWI30_07935	ENOG4105E5Q	amino acid AbC transporter
GWI30_07940	ENOG4106TNF	Periplasmic binding protein
GWI30_07955	ENOG4105D7V	transposase
GWI30_07965	ENOG4105CXY	transporter
GWI30_07970	ENOG4105BZU	Histidine kinase
GWI30_07975	ENOG4108KX4	response regulator
GWI30_07980	ENOG4105NXH	GreA GreB family elongation factor
GWI30_08005	ENOG4105C9W	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity (By similarity)
GWI30_08010	ENOG4108ISG	Major Facilitator
GWI30_08015	ENOG4105DGU	Histone deacetylase
GWI30_08025	ENOG4105DVT	helicase
GWI30_08040	ENOG4105CGF	Aromatic amino acid aminotransferase
GWI30_08050	ENOG4105D7A	ATP-binding protein
GWI30_08065	ENOG4108EQH	DNA internalization-related competence protein ComEC Rec2
GWI30_08070	ENOG4105BZ1	(ABC) transporter
GWI30_08075	ENOG4105CHD	Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) (By similarity)
GWI30_08080	ENOG4105W49	UPF0434 protein
GWI30_08085	ENOG4105CET	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria (By similarity)
GWI30_08090	ENOG4105WH1	Two component transcriptional regulator luxr family
GWI30_08095	ENOG4105CII	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity)
GWI30_08160	ENOG410600T	transposase
GWI30_08190	ENOG4108TGY	Glutathione S-transferase
GWI30_08195	ENOG4105Y3U	Transglycosylase-associated protein
GWI30_08200	ENOG4105F10	Catalyzes the hydrolysis of the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1- phosphate (lipid X) and UMP (By similarity)
GWI30_08210	ENOG4108R5K	PPIases accelerate the folding of proteins (By similarity)
GWI30_08215	ENOG4105C8N	cysteinyl-tRNA synthetase
GWI30_08230	ENOG410600T	transposase
GWI30_08255	ENOG410600T	transposase
GWI30_08280	ENOG410620I	Diguanylate cyclase
GWI30_08320	ENOG4108ZJT	translation initiation factor, Sui1
GWI30_08340	ENOG4107QQ4	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans (By similarity)
GWI30_08345	ENOG4105CZX	twitching motility protein
GWI30_08360	ENOG4108ESU	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Involved in the translocation of the substrate across the membrane (By similarity)
GWI30_08365	ENOG41080WI	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system (By similarity)
GWI30_08370	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
GWI30_08375	ENOG41080IJ	Diacylglycerol kinase
GWI30_08380	ENOG4108JQ1	Dehydrogenase
GWI30_08385	ENOG4105E66	phosphoriboisomerase A
GWI30_08390	ENOG4105MK2	5-formyltetrahydrofolate cyclo-ligase
GWI30_08400	ENOG4105DUK	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity)
GWI30_08405	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
GWI30_08410	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
GWI30_08415	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
GWI30_08425	ENOG4107QS8	(LipO)protein
GWI30_08450	ENOG4105C1J	atp-dependent rna helicase
GWI30_08475	ENOG4108Z4X	TRANSCRIPTIONal
GWI30_08485	ENOG4105BZ8	glutamate synthase
GWI30_08490	ENOG4105CBC	glutamate synthase
GWI30_08495	ENOG4105N5T	Radical SAM Protein
GWI30_08500	ENOG4105F2I	Transposase
GWI30_08535	ENOG4105C85	amino acid
GWI30_08545	ENOG4105CF9	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation (By similarity)
GWI30_08550	ENOG4108HRN	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate (By similarity)
GWI30_08555	ENOG4105DKW	ABC transporter
GWI30_08570	ENOG4105D01	(LipO)protein
GWI30_08575	ENOG4105YVM	Phosphoesterase, PA-phosphatase related
GWI30_08580	ENOG4105CJ0	Catalyzes the oxidation of erythronate-4-phosphate to 3- hydroxy-2-oxo-4-phosphonooxybutanoate (By similarity)
GWI30_08585	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
GWI30_08595	ENOG4105DI7	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity)
GWI30_08600	ENOG4107QTG	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA (By similarity)
GWI30_08605	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
GWI30_08610	ENOG4108S3P	Sporulation domain protein
GWI30_08615	ENOG4108Z0T	Part of a sulfur-relay system (By similarity)
GWI30_08620	ENOG4105EM2	membrane
GWI30_08625	ENOG4108MN8	Membrane
GWI30_08635	ENOG4105C7F	AcnD-accessory protein PrpF
GWI30_08640	ENOG4108I0Z	Aconitate hydratase
GWI30_08645	ENOG4105BZN	citrate synthase
GWI30_08650	ENOG4105CR4	methylisocitrate lyase
GWI30_08660	ENOG410600T	transposase
GWI30_08670	ENOG4105E2B	Taurine dioxygenase
GWI30_08680	ENOG4108J8C	transporter major facilitator family protein
GWI30_08690	ENOG4105HMI	Membrane
GWI30_08710	ENOG4105D25	secreted protein
GWI30_08735	ENOG4105CEY	Amp-dependent synthetase and ligase
GWI30_08740	ENOG4107RHT	methyl-accepting chemotaxis sensory transducer with Pas Pac sensor
GWI30_08745	ENOG4105BZU	Histidine kinase
GWI30_08750	ENOG4108W1A	pseudouridine synthase
GWI30_08760	ENOG4105E6K	4-Hydroxyphenylpyruvate dioxygenase
GWI30_08765	ENOG4105F1J	Homogentisate 1,2-dioxygenase
GWI30_08775	ENOG4108RXX	maleylacetoacetate isomerase
GWI30_08795	ENOG4105CAQ	asparagine synthetase
GWI30_08805	ENOG4105D4U	had-superfamily hydrolase, subfamily iia
GWI30_08855	ENOG4105EE5	Membrane protein terC
GWI30_08865	ENOG4105CQB	FAD linked oxidase domain protein
GWI30_08875	ENOG4105KA0	thioesterase Superfamily protein
GWI30_08880	ENOG4105C1J	atp-dependent rna helicase
GWI30_08885	ENOG4105EQ2	LysR family Transcriptional regulator
GWI30_08895	ENOG4105D3Y	Na H antiporter
GWI30_08900	ENOG4105DH5	Responsible for the end-turnover of tRNA specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis (By similarity)
GWI30_08910	ENOG4105EIY	sodium-type flagellar protein motY
GWI30_08915	ENOG4105ECY	inositol monophosphatase
GWI30_08930	ENOG4105CYM	Glutathione S-transferase
GWI30_08940	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
GWI30_08945	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
GWI30_08950	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
GWI30_08955	ENOG4105E5M	Multidrug resistance protein D
GWI30_08965	ENOG4107YUN	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division (By similarity)
GWI30_08975	ENOG4105D0A	hydroxylase
GWI30_08980	ENOG4105EAK	ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family
GWI30_08985	ENOG4105D43	The glycine cleavage system catalyzes the degradation of glycine (By similarity)
GWI30_08990	ENOG4105KE9	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity)
GWI30_08995	ENOG4105CBI	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
GWI30_09000	ENOG4105F2I	Transposase
GWI30_09035	ENOG4105D3R	alkyl hydroperoxide reductase
GWI30_09040	ENOG4105W87	Cbs domain
GWI30_09045	ENOG4105E2N	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) (By similarity)
GWI30_09050	ENOG4105C6U	Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity)
GWI30_09055	ENOG4105VIE	preprotein translocase, subunit YajC
GWI30_09060	ENOG4107QN8	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
GWI30_09065	ENOG4107RAB	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
GWI30_09070	ENOG4105M78	Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide (By similarity)
GWI30_09105	ENOG4108ZF1	Transcriptional regulator, BadM Rrf2 family
GWI30_09110	ENOG4105C3J	Cysteine desulfurase
GWI30_09115	ENOG4107XTC	May be involved in the formation or repair of Fe-S clusters present in iron-sulfur proteins
GWI30_09120	ENOG4108Z4V	iron-sulfur cluster assembly
GWI30_09125	ENOG4108SWN	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA (By similarity)
GWI30_09130	ENOG4105C9I	Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB
GWI30_09135	ENOG4108ZIT	Ferredoxin, 2FE-2S
GWI30_09145	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
GWI30_09150	ENOG4108UGX	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity)
GWI30_09155	ENOG4105C55	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
GWI30_09165	ENOG4105HSZ	Cytoskeletal protein that is involved in cell-shape control through regulation of the length of the long axis (By similarity)
GWI30_09170	ENOG4105C4E	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (By similarity)
GWI30_09175	ENOG4105CUT	histidyl-tRNA synthetase
GWI30_09180	ENOG4105N21	Membrane
GWI30_09185	ENOG4105CNE	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
GWI30_09190	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
GWI30_09200	ENOG4105CHQ	Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella (By similarity)
GWI30_09205	ENOG4107QIK	phosphoribosylformylglycinamidine synthase
GWI30_09215	ENOG4105CNR	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
GWI30_09220	ENOG4105C8S	subunit m
GWI30_09225	ENOG4105D65	subunit l
GWI30_09230	ENOG41080EA	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
GWI30_09235	ENOG4107UFS	subunit j
GWI30_09240	ENOG4105P3U	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
GWI30_09245	ENOG4105CMZ	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone (By similarity)
GWI30_09250	ENOG4108IEH	NADH dehydrogenase subunit g
GWI30_09255	ENOG4107QIZ	NADH dehydrogenase
GWI30_09260	ENOG4105GKE	subunit e
GWI30_09265	ENOG4105CQV	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
GWI30_09270	ENOG4105ES3	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
GWI30_09275	ENOG4105KWU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
GWI30_09280	ENOG4105ER2	Ompa motb domain protein
GWI30_09285	ENOG4105E14	MotA TolQ exbB proton channel
GWI30_09305	ENOG4105HA9	of methanol dehydrogenase type
GWI30_09315	ENOG4105HPZ	Involved in the removal of murein from the sacculus. May also facilitate integration of nascent murein strands into the sacculus by cleaving the peptide bonds between neighboring strands in mature murein (By similarity)
GWI30_09325	ENOG4105VFU	Rna-binding protein
GWI30_09330	ENOG4107RGM	aldo keto reductase
GWI30_09355	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
GWI30_09360	ENOG4105CBN	LysR family transcriptional regulator
GWI30_09370	ENOG4105BZU	Histidine kinase
GWI30_09375	ENOG4105CFC	Transporter
GWI30_09395	ENOG4108SC4	)-transporter
GWI30_09400	ENOG4105DUM	transcriptional regulator, lysR family
GWI30_09405	ENOG4108JEN	Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate (By similarity)
GWI30_09410	ENOG4105CAT	Cytidine monophosphate kinase
GWI30_09415	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
GWI30_09420	ENOG41080YA	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
GWI30_09430	ENOG4105CFV	Tetratricopeptide repeat protein
GWI30_09435	ENOG4106EG9	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) (By similarity)
GWI30_09450	ENOG4105FD2	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) (By similarity)
GWI30_09455	ENOG4105EIZ	Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity)
GWI30_09460	ENOG4105VRT	cytoplasmic protein
GWI30_09465	ENOG4108WBT	adenosyltransferase
GWI30_09475	ENOG4107S6Z	Na H antiporter
GWI30_09490	ENOG4108RMJ	sensory transduction regulator
GWI30_09515	ENOG4105CAF	HipA N-terminal domain protein
GWI30_09595	ENOG4105XUP	Phage derived protein Gp49-like (DUF891)
GWI30_09605	ENOG4105F2I	Transposase
GWI30_09615	ENOG410626R	Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity)
GWI30_09635	ENOG4105CAF	HipA N-terminal domain protein
GWI30_09755	ENOG410600T	transposase
GWI30_09760	ENOG410600T	transposase
GWI30_09765	ENOG4105F2I	Transposase
GWI30_09790	ENOG4108UUM	single-stranded DNA-binding protein
GWI30_09795	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
GWI30_09800	ENOG4105KT5	UmuD protein
GWI30_09820	ENOG4105F5W	AtP-binding protein
GWI30_09830	ENOG410600T	transposase
GWI30_09910	ENOG4105C3J	Cysteine desulfurase
GWI30_09920	ENOG410600T	transposase
GWI30_09975	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
GWI30_09980	ENOG4105C28	cystathionine
GWI30_09990	ENOG4108RYK	Nad-dependent epimerase dehydratase
GWI30_09995	ENOG4105CR8	Transcriptional regulator
GWI30_10005	ENOG4105UEI	Transcriptional Regulator AraC Family
GWI30_10010	ENOG4105E0K	tonB-dependent siderophore receptor
GWI30_10025	ENOG4105DZ2	Transcriptional regulator
GWI30_10030	ENOG4105DSS	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation (By similarity)
GWI30_10050	ENOG4105MWK	D-amino acid dehydrogenase, small subunit
GWI30_10055	ENOG4105EXX	Deoxyribodipyrimidine photolyase-related protein
GWI30_10065	ENOG41061WM	D-Alanyl-D-Alanine
GWI30_10070	ENOG4108DMF	Cytochrome C biogenesis protein
GWI30_10075	ENOG4107QX9	Thiol disulfide interChange protein
GWI30_10080	ENOG4105DA4	cytochrome c-type biogenesis protein
GWI30_10085	ENOG4105DVI	reductase, NrfD
GWI30_10090	ENOG4105D3S	4Fe-4S Ferredoxin, iron-sulfur binding domain protein
GWI30_10095	ENOG4105JJ8	Cytochrome c nitrite reductase, pentaheme subunit
GWI30_10110	ENOG4105CHG	glycolate oxidase (iron-sulfur subunit)
GWI30_10115	ENOG4108KJ0	anaerobic glycerol-3-phosphate dehydrogenase, subunit B
GWI30_10120	ENOG4107R5Y	anaerobic glycerol-3-phosphate dehydrogenase, subunit A
GWI30_10125	ENOG4105K5B	UPF0225 protein
GWI30_10130	ENOG4105C8Q	Methyl-accepting chemotaxis
GWI30_10135	ENOG4105E2R	ROK family
GWI30_10140	ENOG4105CEQ	signal transduction histidine kinase regulating citrate malate metabolism
GWI30_10145	ENOG4108MRH	transcriptional regulatory protein
GWI30_10175	ENOG4105CHQ	Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella (By similarity)
GWI30_10180	ENOG4105D0C	transport protein
GWI30_10195	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
GWI30_10205	ENOG4105DQR	SNARE associated Golgi
GWI30_10215	ENOG410635M	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein (By similarity)
GWI30_10220	ENOG4105DKR	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity)
GWI30_10225	ENOG4105C05	Multifunctional regulator of fatty acid metabolism (By similarity)
GWI30_10230	ENOG4105ED1	spovr family
GWI30_10235	ENOG4106AKX	UPF0229 protein
GWI30_10240	ENOG4105CYN	Serine protein kinase
GWI30_10245	ENOG4105C9U	ATP-dependent DNA helicase RecQ
GWI30_10250	ENOG4107QV7	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system) (By similarity)
GWI30_10255	ENOG4105C44	Serine transporter
GWI30_10260	ENOG410600T	transposase
GWI30_10290	ENOG410600T	transposase
GWI30_10295	ENOG4107QQN	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties (By similarity)
GWI30_10310	ENOG4105C8P	)-transporter
GWI30_10315	ENOG4105K63	Thioredoxin
GWI30_10320	ENOG4105BZU	Histidine kinase
GWI30_10325	ENOG4105BZ1	(ABC) transporter
GWI30_10330	ENOG4105BZ1	(ABC) transporter
GWI30_10350	ENOG4105WQ3	Rna-binding protein
GWI30_10360	ENOG4105D1N	poly(r)-hydroxyalkanoic acid synthase, class
GWI30_10380	ENOG4107XGF	functions in a salvage pathway. Uses pyridoxamine (By similarity)
GWI30_10385	ENOG41061CK	Antibiotic biosynthesis monooxygenase
GWI30_10390	ENOG4105EFU	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin (By similarity)
GWI30_10400	ENOG4105DUM	transcriptional regulator, lysR family
GWI30_10410	ENOG4105D1S	lipid A biosynthesis
GWI30_10415	ENOG4105D1S	lipid A biosynthesis
GWI30_10425	ENOG4105EUB	pirin domain protein
GWI30_10435	ENOG4105CQ2	DNA polymerase
GWI30_10465	ENOG4107QI1	Mate efflux family protein
GWI30_10470	ENOG4105W1I	UPF0253 protein
GWI30_10475	ENOG4108R6K	riboflavin synthase, subunit alpha
GWI30_10485	ENOG4105D7V	transposase
GWI30_10495	ENOG4107UW8	HAD-superfamily hydrolase subfamily IA variant 3
GWI30_10500	ENOG4108HH9	Catalyzes two reactions the first one is the production of beta-formyl glycinamide ribonucleotide (GAR) from formate, ATP and beta GAR
GWI30_10505	ENOG4108SXK	Transporter Drug Metabolite Exporter family
GWI30_10510	ENOG4108V3G	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity)
GWI30_10540	ENOG4105XW2	UPF0263 protein
GWI30_10545	ENOG4108VKV	Monofunctional biosynthetic peptidoglycan transglycosylase
GWI30_10550	ENOG4108W5H	UPF0263 protein
GWI30_10555	ENOG4105VJP	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell (By similarity)
GWI30_10560	ENOG4107QMS	site-determining protein
GWI30_10565	ENOG4105K7U	Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization (By similarity)
GWI30_10570	ENOG4105VNG	YcgL domain-containing protein
GWI30_10575	ENOG4105CVE	Lytic murein transglycosylase
GWI30_10585	ENOG4105EJQ	L-serine dehydratase
GWI30_10590	ENOG4105EJQ	L-serine dehydratase
GWI30_10595	ENOG4105NBK	UPF0345 protein
GWI30_10610	ENOG4105CHU	acetyl-coa acetyltransferase
GWI30_10615	ENOG4105CKF	membrane protein involved in aromatic hydrocarbon degradation
GWI30_10620	ENOG4105D58	Diguanylate phosphodiesterase
GWI30_10625	ENOG4105CKF	membrane protein involved in aromatic hydrocarbon degradation
GWI30_10635	ENOG4105CKF	membrane protein involved in aromatic hydrocarbon degradation
GWI30_10680	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
GWI30_10685	ENOG4105CHU	acetyl-coa acetyltransferase
GWI30_10690	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
GWI30_10700	ENOG4108VWS	Yaeq family
GWI30_10735	ENOG4105EHG	Permease protein
GWI30_10750	ENOG4107MBR	17 kDa surface antigen
GWI30_10755	ENOG4105CEY	Amp-dependent synthetase and ligase
GWI30_10760	ENOG4105D29	Helix-turn-helix type 11 domain protein
GWI30_10770	ENOG4105K8F	Phosphoribosyl-amp cyclohydrolase
GWI30_10775	ENOG4105C0S	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity)
GWI30_10780	ENOG4105BZU	Histidine kinase
GWI30_10790	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
GWI30_10795	ENOG4105CJV	Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase
GWI30_10800	ENOG4108UJE	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity)
GWI30_10810	ENOG4105CIH	Imidazole acetol-phosphate transaminase
GWI30_10815	ENOG4105CEK	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity)
GWI30_10820	ENOG4105E21	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity)
GWI30_10830	ENOG4105DVT	helicase
GWI30_10835	ENOG41072GX	Peptidase M22 Glycoprotease
GWI30_10845	ENOG4107J5P	Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC). Is also able to catalyze the hydrolysis of the thioester bond in palmitoyl-CoA in vitro (By similarity)
GWI30_10850	ENOG4105CEY	Amp-dependent synthetase and ligase
GWI30_10855	ENOG4105ZIE	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides (By similarity)
GWI30_10865	ENOG410600T	transposase
GWI30_10920	ENOG4105FBT	Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs (By similarity)
GWI30_10925	ENOG4105WD1	Membrane
GWI30_10930	ENOG4109003	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity)
GWI30_10935	ENOG4107QMP	dna polymerase iii subunits gamma and tau
GWI30_10940	ENOG4105KDX	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection (By similarity)
GWI30_10945	ENOG4105CHJ	isochorismatase hydrolase
GWI30_10950	ENOG4105EUB	pirin domain protein
GWI30_10955	ENOG4105JQN	Transcriptional regulator
GWI30_10960	ENOG4105DWD	nucleoside recognition domain protein
GWI30_10990	ENOG4105CQ7	ATP-dependent helicase
GWI30_11000	ENOG4105KW6	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance (By similarity)
GWI30_11005	ENOG4105BZU	Histidine kinase
GWI30_11010	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
GWI30_11015	ENOG4105C5X	domain protein
GWI30_11020	ENOG4105CR7	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA (By similarity)
GWI30_11025	ENOG4105D4F	Synthesizes selenophosphate from selenide and ATP (By similarity)
GWI30_11035	ENOG4105DR4	Methyltransferase
GWI30_11040	ENOG4108N3W	hemolysin secretion protein
GWI30_11045	ENOG4105VSY	K01512 acylphosphatase EC 3.6.1.7
GWI30_11055	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
GWI30_11060	ENOG4105D1F	ATP-binding protein
GWI30_11065	ENOG4105DBI	uridine monophosphokinase
GWI30_11070	ENOG4105DHP	deoxycytidine triphosphate deaminase
GWI30_11075	ENOG4105CJ3	phosphate transporter
GWI30_11080	ENOG4105D70	Integrase catalytic subunit
GWI30_11090	ENOG4105C03	ribonuclease
GWI30_11095	ENOG4105EI2	Pseudouridine synthase
GWI30_11100	ENOG4108YZS	Had-superfamily hydrolase, subfamily ia, variant 1
GWI30_11105	ENOG4108UHJ	MAF-like protein
GWI30_11115	ENOG4105FCQ	metal-binding, possibly nucleic acid-binding protein
GWI30_11120	ENOG4105VGS	50s ribosomal protein l32
GWI30_11125	ENOG4105C6B	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA (By similarity)
GWI30_11130	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
GWI30_11135	ENOG4105CJF	Malonyl coA-acyl carrier protein transacylase
GWI30_11140	ENOG4105CHR	reductase
GWI30_11145	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
GWI30_11150	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
GWI30_11155	ENOG4105YAZ	4-amino-4-deoxychorismate lyase
GWI30_11160	ENOG4105HHA	aminodeoxychorismate lyase
GWI30_11165	ENOG4108ZMD	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity)
GWI30_11170	ENOG4107QRG	dna polymerase iii
GWI30_11175	ENOG4105F8V	Hydrolase, tatD family
GWI30_11190	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
GWI30_11195	ENOG4105DY2	Paraquat-inducible protein b
GWI30_11200	ENOG4105H2K	paraquat-inducible protein a
GWI30_11210	ENOG4105X2V	dna damage-inducible protein
GWI30_11220	ENOG4105DAN	ATP-dependent protease
GWI30_11225	ENOG4108RKI	Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl- ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)- decenoyl-ACP. Can catalyze the dehydratase reaction for beta- hydroxyacyl-ACPs with saturated chain lengths up to 16 0, being most active on intermediate chain length (By similarity)
GWI30_11230	ENOG4105WFT	During stationary phase, converts 70S ribosomes to an inactive dimeric form (100S ribosomes) (By similarity)
GWI30_11240	ENOG4105C5H	ABC transporter
GWI30_11250	ENOG4105C4H	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA (By similarity)
GWI30_11270	ENOG4107QYT	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor (By similarity)
GWI30_11275	ENOG4105C7I	Dehydrogenase
GWI30_11285	ENOG4105CD8	aminopeptidase N
GWI30_11290	ENOG4105CN1	protease
GWI30_11295	ENOG41073DY	may be a structural element that influences the osmotic activation of ProP at a post-translational level (By similarity)
GWI30_11300	ENOG4108ZGC	gaf domain protein
GWI30_11310	ENOG4105EUH	cytochrome C oxidase, cbb3-type, subunit i
GWI30_11325	ENOG4105D6P	C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex (By similarity)
GWI30_11350	ENOG4105DS0	Transcriptional regulator, Crp Fnr family
GWI30_11355	ENOG4105Q9Y	Universal stress protein
GWI30_11360	ENOG4105CB3	Required for the thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32) (By similarity)
GWI30_11375	ENOG4108K3A	Glutathione S-transferase
GWI30_11380	ENOG4105MRB	Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose (By similarity)
GWI30_11385	ENOG4105C2J	ABC transporter
GWI30_11390	ENOG4105CNN	ABC, transporter
GWI30_11395	ENOG4105E9V	Periplasmic binding protein LacI transcriptional regulator
GWI30_11400	ENOG4108RVA	ribokinase
GWI30_11405	ENOG4105ETE	Transcriptional regulator (LacI family
GWI30_11410	ENOG4105BZU	Histidine kinase
GWI30_11435	ENOG4105BZU	Histidine kinase
GWI30_11440	ENOG4108ZUF	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
GWI30_11445	ENOG4105C6A	phenylalanyl-tRNA synthetase (beta subunit)
GWI30_11450	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
GWI30_11455	ENOG4108YZX	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity)
GWI30_11465	ENOG4108UUX	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity)
GWI30_11470	ENOG4105C22	threonyL-tRNA synthetase
GWI30_11490	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
GWI30_11495	ENOG4108HWB	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
GWI30_11500	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
GWI30_11505	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
GWI30_11510	ENOG4105E05	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
GWI30_11515	ENOG4105XPH	Ferredoxin
GWI30_11520	ENOG4105CA3	membrane-bound lytic murein transglycosylase
GWI30_11525	ENOG4105XZD	Fe-S protein
GWI30_11530	ENOG4105DM4	PTS System
GWI30_11535	ENOG4105DE4	1-phosphofructokinase
GWI30_11540	ENOG4105DTZ	bifunctional PTS system fructose-specific transporter subunit IIA HPr protein
GWI30_11545	ENOG4107B7Y	DNA-binding transcriptional regulator FruR
GWI30_11550	ENOG4105E0U	tyrosine-specific transport protein
GWI30_11555	ENOG4105WJG	Glutathione
GWI30_11560	ENOG4105C1J	atp-dependent rna helicase
GWI30_11575	ENOG4105D10	5-enolpyruvylshikimate-3-phosphate phospholyase
GWI30_11580	ENOG4105C76	Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue (By similarity)
GWI30_11585	ENOG4108DG9	Smr protein MutS2
GWI30_11595	ENOG4107TB6	phosphoglycerate mutase
GWI30_11625	ENOG4108Z8G	Alkylphosphonate utilization operon protein PhnA
GWI30_11635	ENOG410829K	Lysine exporter protein (Lyse ygga)
GWI30_11650	ENOG4105JAB	phenazine biosynthesis protein, phzf family
GWI30_11685	ENOG4105DUC	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division (By similarity)
GWI30_11690	ENOG4105DAH	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF (By similarity)
GWI30_11695	ENOG4105GHU	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid partitioning. Probably acts via its interaction with MukB and MukE. Overexpression results in anucleate cells. It has a calcium binding activity (By similarity)
GWI30_11700	ENOG4106371	Methyltransferase
GWI30_11705	ENOG4107S90	membrAne
GWI30_11715	ENOG4105CTQ	phosphohexokinase
GWI30_11720	ENOG4105CH2	amidohydrolase
GWI30_11725	ENOG4105PAD	Hydrolase
GWI30_11730	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
GWI30_11780	ENOG4105CPB	ATP-dependent endonuclease of the OLD family
GWI30_11785	ENOG4105ECQ	AraC Family Transcriptional Regulator
GWI30_11795	ENOG4105VP0	transcriptional regulator, lysR family
GWI30_11800	ENOG4105EJ9	Membrane
GWI30_11805	ENOG4106IUH	DTW domain containing protein
GWI30_11815	ENOG4105CPF	Cell wall formation (By similarity)
GWI30_11830	ENOG4105C1J	atp-dependent rna helicase
GWI30_11835	ENOG4105K5X	acetyltransferase
GWI30_11865	ENOG4105BZU	Histidine kinase
GWI30_11880	ENOG4105CBN	LysR family transcriptional regulator
GWI30_11885	ENOG4105CHR	reductase
GWI30_11890	ENOG4105CS2	ec 3.2.1.21
GWI30_11895	ENOG4105DND	Transcriptional regulator
GWI30_11900	ENOG4105BZU	Histidine kinase
GWI30_11910	ENOG4107QKC	Oxidoreductase alpha (molybdopterin) subunit
GWI30_11915	ENOG4107H9G	Necessary for formate dehydrogenase activity (By similarity)
GWI30_11920	ENOG4105F2I	Transposase
GWI30_11945	ENOG4105W5Q	DNA repair protein (RadC
GWI30_11975	ENOG4107XZC	Restriction modification system DNA (Specificity
GWI30_11980	ENOG4105CVR	type I restriction-modification system
GWI30_12000	ENOG4105HF0	Membrane
GWI30_12005	ENOG4105D5Q	Arginine ornithine antiporter
GWI30_12010	ENOG4105CHR	reductase
GWI30_12015	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
GWI30_12020	ENOG4105E39	Enoyl-CoA hydratase
GWI30_12025	ENOG4105E39	Enoyl-CoA hydratase
GWI30_12030	ENOG4105C1G	acyl-Coa dehydrogenase
GWI30_12035	ENOG4105C26	Dehydrogenase
GWI30_12040	ENOG4105C1G	acyl-Coa dehydrogenase
GWI30_12045	ENOG4107QX3	carboxylase
GWI30_12050	ENOG4105E39	Enoyl-CoA hydratase
GWI30_12060	ENOG4105CBH	Hydroxymethylglutaryl-CoA lyase
GWI30_12075	ENOG4106HK8	GPR1 FUN34 yaaH family protein
GWI30_12090	ENOG4105BZG	amino acid carrier protein
GWI30_12095	ENOG41060WC	Enoyl-CoA hydratase
GWI30_12105	ENOG4105DE5	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity (By similarity)
GWI30_12110	ENOG41062QD	Membrane
GWI30_12115	ENOG4107QN1	sodium solute
GWI30_12120	ENOG4105C5H	ABC transporter
GWI30_12125	ENOG4105EIN	peptidylprolyl cis-trans isomerase
GWI30_12130	ENOG4105K70	DNA-binding protein
GWI30_12135	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
GWI30_12140	ENOG4105CHN	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
GWI30_12145	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
GWI30_12150	ENOG4105DEA	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation
GWI30_12165	ENOG4105DK2	UPF0207 protein
GWI30_12170	ENOG4105D60	lipoprotein releasing system transmembrane protein
GWI30_12175	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
GWI30_12180	ENOG4105D60	lipoprotein releasing system transmembrane protein
GWI30_12190	ENOG4108JA2	transcriptioN-repair coupling factor
GWI30_12195	ENOG4105CZI	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
GWI30_12200	ENOG4108J59	Extracellular solute-binding protein, family 5
GWI30_12205	ENOG4108IPJ	Membrane
GWI30_12215	ENOG4108BY2	phosphohistidine phosphatase
GWI30_12220	ENOG4107QXK	peptidase
GWI30_12225	ENOG4105FQ6	thiopurine methyltransferase
GWI30_12265	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
GWI30_12270	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
GWI30_12280	ENOG4105C9C	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity)
GWI30_12290	ENOG4105DVS	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
GWI30_12295	ENOG4105D4P	Coproporphyrinogen iii oxidase
GWI30_12300	ENOG41090EK	ompa motb domain protein
GWI30_12305	ENOG4108KHX	Diguanylate cyclase
GWI30_12310	ENOG4108WS1	
GWI30_12320	ENOG41090A4	Pterin carbinolamine dehydratase
GWI30_12325	ENOG4105MIR	Phenylalanine 4-monooxygenase
GWI30_12330	ENOG4106K28	UPF0283 membrane protein
GWI30_12335	ENOG4105CM6	amino acid regulated cytosolic protein
GWI30_12345	ENOG4105YYT	phage shock protein B
GWI30_12350	ENOG41087YS	Phage shock protein A
GWI30_12355	ENOG4105E51	psp operon transcriptional activator
GWI30_12360	ENOG4108J59	Extracellular solute-binding protein, family 5
GWI30_12365	ENOG4108I5W	peptide transport system, permease protein
GWI30_12370	ENOG4108EU3	peptide transport system, permease
GWI30_12375	ENOG4108JQ3	Peptide ABC transporter ATP-binding protein
GWI30_12380	ENOG4108JQ2	peptide transport system atp-binding protein
GWI30_12385	ENOG4105FR9	TRNA-(Ms 2 io 6 A)-hydroxylase
GWI30_12390	ENOG4105DDV	Transcriptional regulator (LacI family
GWI30_12400	ENOG4105CS2	ec 3.2.1.21
GWI30_12405	ENOG4105CBA	glutamine phosphoribosylpyrophosphate amidotransferase
GWI30_12410	ENOG4105E96	Colicin v production protein
GWI30_12415	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
GWI30_12420	ENOG4105D1H	recombination factor protein RarA
GWI30_12425	ENOG4107Y7W	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) (By similarity)
GWI30_12430	ENOG4105CNU	cell division protein FtsK
GWI30_12435	ENOG4105EW9	transcriptional regulator AsnC family
GWI30_12440	ENOG4105DCF	alanine dehydrogenase
GWI30_12445	ENOG4105C3M	thioredoxin reductase
GWI30_12450	ENOG4106TD9	Diguanylate cyclase
GWI30_12455	ENOG4107MBR	17 kDa surface antigen
GWI30_12460	ENOG4108R4Z	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine (By similarity)
GWI30_12465	ENOG4105DWA	May conjugate Arg from its aminoacyl-tRNA to the N- termini of proteins containing an N-terminal aspartate or glutamate
GWI30_12470	ENOG4105K9U	however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity)
GWI30_12475	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
GWI30_12480	ENOG4105KAE	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation (By similarity)
GWI30_12485	ENOG4105VEQ	Cold shock protein
GWI30_12490	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
GWI30_12510	ENOG4105DDY	UPF0142 protein ycaO
GWI30_12515	ENOG4105TMB	Formate nitrite transporter
GWI30_12520	ENOG4105C6N	Formate acetyltransferase
GWI30_12535	ENOG4105CH8	Succinyl-CoA ligase ADP-forming subunit alpha
GWI30_12540	ENOG4105CMV	Succinyl-CoA synthetase subunit beta
GWI30_12545	ENOG4105C7S	Dehydrogenase
GWI30_12550	ENOG4105C7P	2-oxoglutarate dehydrogenase, E1
GWI30_12555	ENOG4105E33	succinate dehydrogenase
GWI30_12560	ENOG4105C00	Succinate dehydrogenase (Flavoprotein subunit)
GWI30_12565	ENOG4105N1I	succinate dehydrogenase, hydrophobic membrane anchor protein
GWI30_12570	ENOG4108UTY	succinate dehydrogenase, cytochrome b556 subunit
GWI30_12575	ENOG4105BZN	citrate synthase
GWI30_12590	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
GWI30_12595	ENOG4105CWG	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34 (By similarity)
GWI30_12605	ENOG4105CEE	C4-dicarboxylate transporter
GWI30_12620	ENOG4108VKG	metal-dependent hydrolase
GWI30_12635	ENOG4105NRA	50s ribosomal protein l31 type b
GWI30_12640	ENOG4105YK5	50S ribosomal protein L36
GWI30_12650	ENOG4105CNN	ABC, transporter
GWI30_12655	ENOG4105C2J	ABC transporter
GWI30_12660	ENOG4105DMK	Periplasmic binding protein LacI transcriptional regulator
GWI30_12665	ENOG4105EF1	ribulokinase
GWI30_12675	ENOG4105CAC	Catalyzes the conversion of L-arabinose to L-ribulose (By similarity)
GWI30_12680	ENOG4105ETT	transcriptional Regulator, LysR family
GWI30_12685	ENOG4105CHM	Aminotransferase
GWI30_12720	ENOG4105DDT	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP (By similarity)
GWI30_12725	ENOG4105CJB	Exodeoxyribonuclease I
GWI30_12735	ENOG4107R49	K07407 alpha-galactosidase EC 3.2.1.22
GWI30_12740	ENOG4105VAW	lrga family
GWI30_12745	ENOG41067MG	lrgb family
GWI30_12750	ENOG4107T42	This enzyme scavenge exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis (By similarity)
GWI30_12755	ENOG4108IQE	Amp-dependent synthetase and ligase
GWI30_12760	ENOG4105MH2	YfcL protein
GWI30_12770	ENOG4105EE5	Membrane protein terC
GWI30_12775	ENOG4105VNT	transposase (IS4 family) protein
GWI30_12780	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
GWI30_12785	ENOG4105CMY	5-enolpyruvylshikimate-3-phosphate synthase
GWI30_12790	ENOG4107QM1	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine (By similarity)
GWI30_12795	ENOG4105C10	Electron transfer flavoprotein
GWI30_12800	ENOG4105BZJ	Electron transfer flavoprotein
GWI30_12805	ENOG4105DWH	electron transfer flavoprotein-ubiquinone oxidoreductase
GWI30_12810	ENOG4105DWH	electron transfer flavoprotein-ubiquinone oxidoreductase
GWI30_12820	ENOG4105QZU	Inner membrane protein YfeZ
GWI30_12835	ENOG4105D05	Receptor
GWI30_12840	ENOG4105DQ5	transport system permease protein
GWI30_12845	ENOG4105TVJ	transport system, permease
GWI30_12850	ENOG4105E0A	ABC, transporter
GWI30_12855	ENOG4108TSE	Transferase
GWI30_12865	ENOG4105C0W	non-ribosomal peptide synthetase
GWI30_12875	ENOG4105X17	23-dihydro-2,3-dihydroxybenzoate dehydrogenase
GWI30_12880	ENOG4105CEY	Amp-dependent synthetase and ligase
GWI30_12885	ENOG4105WQI	isochorismatase
GWI30_12890	ENOG4108IQC	2,3-dihydroxybenzoate-AMP ligase
GWI30_12900	ENOG4105F3T	(LipO)protein
GWI30_12910	ENOG4107QQ4	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans (By similarity)
GWI30_12915	ENOG4105BZU	Histidine kinase
GWI30_12930	ENOG4105C8Q	Methyl-accepting chemotaxis
GWI30_12935	ENOG4107RE1	Inosine-guanosine kinase
GWI30_12940	ENOG4105WJG	Glutathione
GWI30_12945	ENOG4105CFX	Catalyzes the ferrous insertion into protoporphyrin IX (By similarity)
GWI30_12950	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
GWI30_12955	ENOG4105CJX	Molecular chaperone. Has ATPase activity (By similarity)
GWI30_12960	ENOG4105F3K	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity)
GWI30_12965	ENOG4105F2I	Transposase
GWI30_12980	ENOG4105CHH	sulfate transporter
GWI30_12985	ENOG410600T	transposase
GWI30_13060	ENOG4105C2C	drug resistance transporter, Bcr CflA
GWI30_13080	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
GWI30_13095	ENOG4105F2I	Transposase
GWI30_13105	ENOG4108ZZK	Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source (By similarity)
GWI30_13110	ENOG4107QR9	Iron-sulfur cluster binding protein
GWI30_13115	ENOG4105CHG	glycolate oxidase (iron-sulfur subunit)
GWI30_13120	ENOG4105DAA	L-lactate
GWI30_13125	ENOG4105CR8	Transcriptional regulator
GWI30_13135	ENOG4105MSB	protein, conserved in bacteria
GWI30_13150	ENOG4107QXP	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
GWI30_13155	ENOG4107QZM	n-acetylglutamate synthase
GWI30_13165	ENOG4105CFH	Aspartokinase
GWI30_13175	ENOG4107T7U	Sulfatase
GWI30_13195	ENOG4105K8R	UPF0145 protein
GWI30_13205	ENOG4105CEP	NADH dehydrogenase
GWI30_13210	ENOG4105D0Y	UPF0227 protein
GWI30_13215	ENOG4105DPN	Oligoendopeptidase f
GWI30_13225	ENOG4105CKW	Inner membrane protein yedI
GWI30_13235	ENOG4107RAB	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
GWI30_13240	ENOG4107QN8	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
GWI30_13245	ENOG4105D7V	transposase
GWI30_13295	ENOG4105K59	histidine triad (HIT) protein
GWI30_13310	ENOG4105CD3	dihydroorotase
GWI30_13325	ENOG4107QJT	sodium dicarboxylate symporter
GWI30_13335	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
GWI30_13340	ENOG4105DU1	integral membrane protein, terc
GWI30_13345	ENOG4108JQ7	(ABC) transporter
GWI30_13350	ENOG4105C3U	ABC transporter
GWI30_13355	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
GWI30_13360	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
GWI30_13365	ENOG4107QSI	ABC, transporter
GWI30_13370	ENOG4105EZI	multiple antibiotic resistance (MarC)-related protein
GWI30_13375	ENOG4105C0A	alcohol dehydrogenase
GWI30_13380	ENOG4105CPI	Metal Dependent Phosphohydrolase
GWI30_13385	ENOG4108HRK	Histidine kinase
GWI30_13390	ENOG4108NEV	two component transcriptional regulator, LytTR family
GWI30_13400	ENOG4105EGS	Mechanosensitive ion channel
GWI30_13410	ENOG4105D7V	transposase
GWI30_13420	ENOG4105KK7	inner membrane protein YiaW
GWI30_13425	ENOG4105EFX	secretion protein, HlyD family
GWI30_13430	ENOG4105CFI	type iii restriction protein res subunit
GWI30_13435	ENOG4106HRJ	d-alanyl-d-alanine carboxypeptidase
GWI30_13440	ENOG41090BQ	Glutaredoxin
GWI30_13450	ENOG4105CHM	Aminotransferase
GWI30_13460	ENOG4105RKW	reductase (By
GWI30_13470	ENOG4107SDU	Methyl-accepting chemotaxis
GWI30_13480	ENOG4108PCN	EamA-like transporter family
GWI30_13485	ENOG4105DGN	Electron transport complex
GWI30_13490	ENOG4108R3D	Electron transport complex
GWI30_13500	ENOG4105D6A	Electron transport complex
GWI30_13505	ENOG4108UQQ	Electron transport complex
GWI30_13515	ENOG4105CSM	endonuclease III
GWI30_13520	ENOG4108UYE	Lactoylglutathione lyase
GWI30_13535	ENOG4105DUF	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively (By similarity)
GWI30_13545	ENOG4105JKQ	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Binds vitamin B12 and delivers it to the periplasmic surface of BtuC (By similarity)
GWI30_13555	ENOG4108C80	FliB family
GWI30_13570	ENOG410600T	transposase
GWI30_13585	ENOG4105MQ3	flagellar protein FliS
GWI30_13600	ENOG4105I03	Flagellin
GWI30_13605	ENOG4105EN6	Membrane
GWI30_13615	ENOG4105D8I	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS (By similarity)
GWI30_13625	ENOG4108JQB	penicillin-binding protein 1C
GWI30_13630	ENOG4105DN3	alpha-2-macroglobulin domain protein
GWI30_13645	ENOG4107QMW	pyridine nucleotide-disulfide oxidoreductase
GWI30_13650	ENOG4105BZU	Histidine kinase
GWI30_13655	ENOG4105F1A	Pyruvate formate-lyase
GWI30_13680	ENOG410600T	transposase
GWI30_13695	ENOG41090SZ	ABC-2 type transporter
GWI30_13750	ENOG4105C3Y	UTP-glucose-1-phosphate uridylyltransferase
GWI30_13755	ENOG4105C1B	dTDP-glucose 4-6-dehydratase
GWI30_13760	ENOG4105DBZ	Dtdp-4-dehydrorhamnose reductase
GWI30_13770	ENOG410600T	transposase
GWI30_13780	ENOG4108URP	Dtdp-4-dehydrorhamnose 3,5-epimerase
GWI30_13785	ENOG4105E12	capsule polysaccharide
GWI30_13790	ENOG41084CK	capsule polysaccharide
GWI30_13795	ENOG4106YG3	ABC transporter
GWI30_13800	ENOG4105DSP	amino acid AbC transporter
GWI30_13805	ENOG4106PMH	Extracellular solute-binding protein family 3
GWI30_13810	ENOG4108JEH	abc transporter atp-binding protein
GWI30_13815	ENOG4105DWU	Membrane
GWI30_13820	ENOG4105VNT	transposase (IS4 family) protein
GWI30_13825	ENOG4105D7V	transposase
GWI30_13840	ENOG4105K89	arsenate reductase
GWI30_13850	ENOG4105ERG	peptidase m48, ste24p
GWI30_13870	ENOG4105D7V	transposase
GWI30_13890	ENOG4105CSR	polyphosphate kinase 2
GWI30_13895	ENOG4108IJ9	(ABC) transporter
GWI30_13905	ENOG4105D56	permease protein
GWI30_13910	ENOG4107FKK	extracellular solute-binding protein family 1
GWI30_13915	ENOG4106V8H	Nucleoid-associated protein
GWI30_13920	ENOG4105PAN	UPF0352 protein
GWI30_13925	ENOG4105E68	Sulfatase
GWI30_13930	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
GWI30_13935	ENOG4105CUG	Oligopeptidase b
GWI30_13955	ENOG4108QSZ	General inhibitor of pancreatic serine proteases inhibits chymotrypsin, trypsin, elastases, factor X, kallikrein as well as a variety of other proteases (By similarity)
GWI30_13960	ENOG4108WFC	UPF0438 protein yifE
GWI30_13975	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
GWI30_13980	ENOG4106MZZ	glycerophosphoryl diester phosphodiesterase
GWI30_13985	ENOG4105C6V	Glycerol-3-phosphate dehydrogenase
GWI30_13990	ENOG4105E98	transcriptional regulator DeoR family
GWI30_14000	ENOG410600T	transposase
GWI30_14010	ENOG4105D8C	Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity)
GWI30_14015	ENOG4108JQ0	Key enzyme in the regulation of glycerol uptake and metabolism (By similarity)
GWI30_14020	ENOG4105HEI	LysR family (Transcriptional regulator
GWI30_14045	ENOG4105CV8	reductase
GWI30_14050	ENOG4105F27	Major Facilitator
GWI30_14060	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
GWI30_14065	ENOG4105C4M	(Ubiquinol oxidase) subunit I
GWI30_14075	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
GWI30_14090	ENOG4105DU6	RNA polymerase
GWI30_14110	ENOG4108Q2J	Inner membrane protein YebE
GWI30_14125	ENOG4106428	Protein of unknown function (DUF2496)
GWI30_14135	ENOG4105JQN	Transcriptional regulator
GWI30_14145	ENOG4105DJ2	Major Facilitator Superfamily
GWI30_14150	ENOG4105FE9	pseudouridine synthase
GWI30_14155	ENOG4105D82	Glutamate dehydrogenase
GWI30_14180	ENOG410600T	transposase
GWI30_14210	ENOG4105BZU	Histidine kinase
GWI30_14225	ENOG4105DP5	Catalyzes the biosynthesis of agmatine from arginine (By similarity)
GWI30_14235	ENOG4105D42	Cleaves the N-terminal amino acid of tripeptides (By similarity)
GWI30_14250	ENOG4105D7V	transposase
GWI30_14270	ENOG4108YYC	ycei family
GWI30_14275	ENOG4105CC0	LysR family Transcriptional regulator
GWI30_14285	ENOG4105CKU	formyltetrahydrofolate synthetase
GWI30_14295	ENOG4105C8Q	Methyl-accepting chemotaxis
GWI30_14300	ENOG4105EUJ	GTP cyclohydrolase i
GWI30_14305	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
GWI30_14310	ENOG4105D06	uba thif-type nad fad binding protein
GWI30_14315	ENOG4105D3C	The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters (By similarity)
GWI30_14320	ENOG4105CGB	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system (By similarity)
GWI30_14325	ENOG4105E0C	molybdate abc transporter
GWI30_14330	ENOG4108S6J	ABC transporter, periplasmic molybdate-binding protein
GWI30_14335	ENOG4108ZAF	Molybdopterin
GWI30_14340	ENOG4105M00	molybdopterin converting factor, subunit 1
GWI30_14345	ENOG4108YXW	Together with MoaA, is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
GWI30_14350	ENOG4108RIR	Molybdenum cofactor biosynthesis protein
GWI30_14355	ENOG4105CUW	cytochrome C-TYPE protein
GWI30_14365	ENOG4105GXZ	Ferredoxin-type protein NapH
GWI30_14370	ENOG4108BGM	Quinol dehydrogenase periplasmic component
GWI30_14375	ENOG4107QIW	Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity)
GWI30_14390	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
GWI30_14395	ENOG4105BZU	Histidine kinase
GWI30_14400	ENOG4105WH1	Two component transcriptional regulator luxr family
GWI30_14415	ENOG4105BZU	Histidine kinase
GWI30_14425	ENOG4105CHW	UPF0052 protein
GWI30_14435	ENOG4105E7A	Glutamine amidotransferase
GWI30_14440	ENOG4105F55	Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate (By similarity)
GWI30_14445	ENOG4107QPN	acyl-Coa dehydrogenase
GWI30_14450	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
GWI30_14460	ENOG4107RZZ	dna polymerase iii epsilon subunit
GWI30_14465	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
GWI30_14490	ENOG4108F3G	Type I restriction-modification system, R subunit
GWI30_14495	ENOG4108UMW	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
GWI30_14500	ENOG4105D1A	Methyltransferase
GWI30_14505	ENOG4108RW0	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
GWI30_14510	ENOG4105E9H	Lytic Murein transglycosylase
GWI30_14525	ENOG4105NAU	thioesterase Superfamily protein
GWI30_14535	ENOG41060NJ	transcriptional regulator
GWI30_14540	ENOG4107SC1	transglycosylase
GWI30_14550	ENOG4108WPH	sigma 54 modulation protein ribosomal protein S30EA
GWI30_14575	ENOG4105CFU	surface antigen
GWI30_14585	ENOG4105KQ5	peptidylprolyl cis-trans isomerase
GWI30_14595	ENOG4107ZN8	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity (By similarity)
GWI30_14605	ENOG4105VNH	ABC transporter solute-binding protein
GWI30_14615	ENOG4108VGW	abc transporter atp-binding protein
GWI30_14620	ENOG4108T9J	Cdp-alcohol phosphatidyltransferase
GWI30_14625	ENOG4105CVE	Lytic murein transglycosylase
GWI30_14630	ENOG41090MY	MarR family Transcriptional regulator
GWI30_14640	ENOG4107QIX	Phosphoglucomutase (EC 5.4.2.2
GWI30_14645	ENOG4107CDU	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated (By similarity)
GWI30_14650	ENOG4105EV9	Alpha Beta Hydrolase
GWI30_14660	ENOG4105NNH	LexA regulated protein
GWI30_14665	ENOG4105MHQ	Low-potential electron donor to a number of redox enzymes (By similarity)
GWI30_14675	ENOG41090R7	Ferric uptake
GWI30_14680	ENOG4105CX6	glutaminyL-tRNA synthetase
GWI30_14685	ENOG4105E2D	ec 3.2.1.52
GWI30_14690	ENOG4105CI1	PTS System
GWI30_14695	ENOG4105CKA	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion (By similarity)
GWI30_14700	ENOG4105CE4	GlcNAc 6-P deacetylase
GWI30_14705	ENOG4105E2R	ROK family
GWI30_14710	ENOG4105DIJ	Phosphoethanolamine transferase
GWI30_14715	ENOG4105CDY	transcriptional regulatory protein
GWI30_14720	ENOG4105C9M	aspartyl-trna synthetase
GWI30_14730	ENOG41081XQ	Conserved Protein
GWI30_14735	ENOG4105DA6	Catalyzes the conversion of 5-methoxyuridine (mo5U) to uridine-5-oxyacetic acid (cmo5U) at position 34 in tRNA. May also participate in the methylation of uridine-5-oxyacetic acid (cmo5U) to uridine-5-oxyacetic acid methyl ester (mcmo5U) (By similarity)
GWI30_14740	ENOG4105PFA	Catalyzes the conversion of 5-hydroxyuridine (ho5U) to 5-methoxyuridine (mo5U) at position 34 in tRNA (By similarity)
GWI30_14760	ENOG4105C5Q	Transcriptional regulator
GWI30_14765	ENOG4107TT5	NLP P60 protein
GWI30_14775	ENOG4107RGH	Aldehyde dehydrogenase
GWI30_14780	ENOG4108RZE	Tetr family transcriptional regulator
GWI30_14795	ENOG4105C6T	cysteine synthase
GWI30_14815	ENOG4105UQX	Mate efflux family protein
GWI30_14825	ENOG4105Z2P	Protein of unknown function (DUF465)
GWI30_14830	ENOG4105D95	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin (By similarity)
GWI30_14840	ENOG4105QVC	MOSC domain-containing protein
GWI30_14840	ENOG4105QVC	MOSC domain-containing protein
GWI30_14845	ENOG4105D0M	Protease HtpX homolog
GWI30_14850	ENOG4105E78	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity)
GWI30_14855	ENOG410626R	Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity)
GWI30_14860	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
GWI30_14865	ENOG4105CZF	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism (By similarity)
GWI30_14870	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
GWI30_14885	ENOG4105C5S	asparaginyl-tRNA synthetase
GWI30_14890	ENOG4105DS2	Anaerobic c4-dicarboxylate transporter
GWI30_14905	ENOG4105KUZ	arsenate reductase
GWI30_14910	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
GWI30_14925	ENOG4105C3N	Participates in control of cell volume in low-osmolarity conditions (By similarity)
GWI30_14940	ENOG410829K	Lysine exporter protein (Lyse ygga)
GWI30_14950	ENOG4105RX8	Protein of unknown function (DUF1523)
GWI30_14965	ENOG4105DU0	nucleoside hydrolase
GWI30_14970	ENOG4105D3G	Pseudouridine synthase
GWI30_14975	ENOG4107SXA	Phosphorylase
GWI30_14985	ENOG4105YRI	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
GWI30_15005	ENOG4105VDB	UPF0125 protein
GWI30_15010	ENOG4108Z1B	Cyclase dehydrase
GWI30_15015	ENOG4108UH4	Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity)
GWI30_15025	ENOG4105DFP	Integrase
GWI30_15085	ENOG4108YYD	acetyltransferase
GWI30_15120	ENOG4108YYX	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. Modulates RNA-binding and helicase activities of the degradosome (By similarity)
GWI30_15130	ENOG41065U4	response regulator
GWI30_15145	ENOG4108JJ9	ABC, transporter
GWI30_15150	ENOG4108JJ8	(ABC) transporter
GWI30_15170	ENOG4108R96	Methyltransferase, YaeB family
GWI30_15190	ENOG4105C6T	cysteine synthase
GWI30_15195	ENOG4105KZ7	phosphocarrier protein hpr
GWI30_15200	ENOG4105BZ3	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity)
GWI30_15205	ENOG4105C5Y	PTS System
GWI30_15210	ENOG4108VKM	cytochrome b561
GWI30_15220	ENOG4105EYH	Exonuclease
GWI30_15225	ENOG4107RH8	nuclease SbcCD subunit D
GWI30_15230	ENOG4105K5X	acetyltransferase
GWI30_15235	ENOG4105DH7	May be involved in recombination (By similarity)
GWI30_15250	ENOG4105CJP	fad dependent oxidoreductase
GWI30_15255	ENOG4107VRI	Transcriptional regulator
GWI30_15260	ENOG4105C26	Dehydrogenase
GWI30_15265	ENOG4108JPW	Aminotransferase
GWI30_15270	ENOG4105CUB	amino acid
GWI30_15275	ENOG4105CUB	amino acid
GWI30_15290	ENOG4108V1T	peptidylprolyl cis-trans isomerase
GWI30_15295	ENOG4105C8E	extradiol ring-cleavage dioxygenase class IIi protein subunit b
GWI30_15300	ENOG4105BZU	Histidine kinase
GWI30_15305	ENOG4105XIQ	Protein of unknown function (DUF2517)
GWI30_15310	ENOG410600T	transposase
GWI30_15340	ENOG4105EQ2	LysR family Transcriptional regulator
GWI30_15345	ENOG4105ENX	hydrolase
GWI30_15355	ENOG4107RTG	Major Facilitator superfamily
GWI30_15380	ENOG4105WKS	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity)
GWI30_15390	ENOG4108T0W	nitrous oxide maturation protein NosY
GWI30_15395	ENOG4105CIG	ABC transporter
GWI30_15430	ENOG4107N1Q	ErfK YbiS YcfS YnhG family protein
GWI30_15445	ENOG4105EBA	Specifically methylates the adenine in position 1618 of 23S rRNA (By similarity)
GWI30_15450	ENOG4107TT5	NLP P60 protein
GWI30_15455	ENOG4107YAK	holo-(acyl carrier protein) synthase 2
GWI30_15460	ENOG4107QR8	Thioredoxin
GWI30_15470	ENOG4105C66	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity)
GWI30_15475	ENOG4105CIY	formyltetrahydrofolate deformylase
GWI30_15500	ENOG4105E4C	Lytic transglycosylase catalytic
GWI30_15505	ENOG4105D8C	Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity)
GWI30_15510	ENOG4105NHU	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group (By similarity)
GWI30_15515	ENOG4105EP9	oxidoreductase
GWI30_15535	ENOG4105CCT	upf0313 protein
GWI30_15540	ENOG4105BZS	acriflavin resistance protein
GWI30_15550	ENOG4105BZU	Histidine kinase
GWI30_15555	ENOG4105D78	K07001 NTE family protein
GWI30_15560	ENOG4105C8J	)-transporter
GWI30_15575	ENOG4105UYK	outer membrane protein a
GWI30_15585	ENOG4105UYK	outer membrane protein a
GWI30_15595	ENOG4105D5G	Transposase
GWI30_15600	ENOG4105UYK	outer membrane protein a
GWI30_15605	ENOG4107R1I	NAD-dependent malic enzyme
GWI30_15610	ENOG4105ECQ	AraC Family Transcriptional Regulator
GWI30_15615	ENOG4105UQX	Mate efflux family protein
GWI30_15620	ENOG4105RKX	Protein of unknown function (DUF2498)
GWI30_15630	ENOG4105C2W	permease
GWI30_15635	ENOG4108KMH	lipoate-protein ligase a
GWI30_15640	ENOG4105BZG	amino acid carrier protein
GWI30_15660	ENOG4105PTV	Nudix Hydrolase
GWI30_15670	ENOG4105CDA	abc transporter atp-binding protein
GWI30_15675	ENOG4105DRP	amino acid AbC transporter
GWI30_15680	ENOG4105EZ7	amino acid ABC transporter
GWI30_15700	ENOG4105CJ1	ABC, transporter
GWI30_15705	ENOG4108V1T	peptidylprolyl cis-trans isomerase
GWI30_15720	ENOG4106N3A	copper homeostasis protein cutc
GWI30_15725	ENOG4105EZX	Catalyzes the phosphorylation of N-acetyl-D-glucosamine (GlcNAc) derived from cell-wall degradation, yielding GlcNAc-6-P (By similarity)
GWI30_15735	ENOG4105ERG	peptidase m48, ste24p
GWI30_15740	ENOG4105DJH	phosphate
GWI30_15745	ENOG4105BZU	Histidine kinase
GWI30_15750	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
GWI30_15755	ENOG4108ZI4	Glyoxalase Bleomycin resistance protein (Dioxygenase
GWI30_15760	ENOG4105BZU	Histidine kinase
GWI30_15765	ENOG4108JU9	GAF modulated sigma54 specific transcriptional regulator Fis family
GWI30_15770	ENOG4105C26	Dehydrogenase
GWI30_15780	ENOG4108IPJ	Membrane
GWI30_15785	ENOG4106YYS	transcriptional regulatory protein
GWI30_15790	ENOG4105CEQ	signal transduction histidine kinase regulating citrate malate metabolism
GWI30_15795	ENOG4107R1I	NAD-dependent malic enzyme
GWI30_15810	ENOG4105J12	Multidrug resistance protein mdtN
GWI30_15840	ENOG4108RDD	Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine (By similarity)
GWI30_15845	ENOG4105CJD	(Anaerobic) ribonucleoside-triphosphate reductase
GWI30_15855	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
GWI30_15860	ENOG4107NPY	receptor for the septal ring structure, may anchor it to the inner-membrane (By similarity)
GWI30_15865	ENOG4105CDB	Required for chromosome condensation and partitioning (By similarity)
GWI30_15870	ENOG4105EXN	Sulfate transport protein CysZ
GWI30_15875	ENOG4105EN6	Membrane
GWI30_15885	ENOG4105EAQ	(twin-arginine translocation) pathway signal
GWI30_15890	ENOG4105DIT	ErfK YbiS YcfS YnhG family protein
GWI30_15925	ENOG4107T9C	Alpha amylase catalytic region
GWI30_15960	ENOG4105BZU	Histidine kinase
GWI30_15965	ENOG4105D3U	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
GWI30_15970	ENOG4105C9K	Endothelin-converting enzyme 1
GWI30_15980	ENOG4105C5H	ABC transporter
GWI30_15985	ENOG4105KNA	-acetyltransferase
GWI30_15995	ENOG4105DVH	amino acid
GWI30_16000	ENOG4105C44	Serine transporter
GWI30_16005	ENOG410642W	LysR family Transcriptional regulator
GWI30_16015	ENOG4107QM9	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA (By similarity)
GWI30_16020	ENOG4105C0B	DNA polymerase III (alpha subunit)
GWI30_16025	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
GWI30_16030	ENOG4105D0V	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
GWI30_16035	ENOG4105DAF	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
GWI30_16040	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
GWI30_16045	ENOG4105D7M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
GWI30_16050	ENOG4108RFI	Molecular chaperone that interacts specifically with outer membrane proteins, thus maintaining the solubility of early folding intermediates during passage through the periplasm (By similarity)
GWI30_16060	ENOG4105DZP	Membrane-associated zinc metalloprotease
GWI30_16065	ENOG4105CEA	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity)
GWI30_16070	ENOG4105KNE	Phosphatidate cytidylyltransferase
GWI30_16080	ENOG4108VCV	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity)
GWI30_16085	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
GWI30_16090	ENOG4105CU7	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity)
GWI30_16095	ENOG4105CE9	30S ribosomal protein S2
GWI30_16100	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
GWI30_16105	ENOG4105E1P	Modifies, by uridylylation or deuridylylation the PII (GlnB) regulatory protein (By similarity)
GWI30_16110	ENOG4105DMJ	Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate (By similarity)
GWI30_16115	ENOG4108T8E	UPF0325 protein
GWI30_16120	ENOG4105CI1	PTS System
GWI30_16125	ENOG4107W52	maltose operon periplasmic protein
GWI30_16130	ENOG4108KDD	Involved in the transport of maltose and maltodextrins (By similarity)
GWI30_16135	ENOG410600T	transposase
GWI30_16140	ENOG4105QDK	Flavodoxin
GWI30_16145	ENOG4105DR9	pseudouridine synthase
GWI30_16150	ENOG4105WP7	tRNA pseudouridine synthase C
GWI30_16175	ENOG4105EXF	Zn-ribbon-containing, possibly nucleic-acid-binding protein
GWI30_16180	ENOG4108T6E	Interacts with the SecY protein in vivo. May bind preferentially to an uncomplexed state of SecY, thus functioning either as a chelating agent for excess SecY in the cell or as a regulatory factor that negatively controls the translocase function (By similarity)
GWI30_16185	ENOG4107R1K	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) (By similarity)
GWI30_16195	ENOG4105BZU	Histidine kinase
GWI30_16200	ENOG4105EWT	decarboxylase family
GWI30_16205	ENOG4105CIQ	May have a role in processing of nucleic acids. It is probably not an exonuclease
GWI30_16210	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
GWI30_16220	ENOG4105EZ6	Catalyzes the 2'-O-methylation at nucleotide C2498 in 23S rRNA (By similarity)
GWI30_16225	ENOG4105M08	Membrane
GWI30_16235	ENOG4105ETT	transcriptional Regulator, LysR family
GWI30_16245	ENOG410600T	transposase
GWI30_16255	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
GWI30_16270	ENOG4105CJ2	(LipO)protein
GWI30_16275	ENOG4105D26	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. The first step is catalyzed by NqrF, which accepts electrons from NADH and reduces ubiquinone-1 to ubisemiquinone by a one-electron transfer pathway (By similarity)
GWI30_16280	ENOG4108IUB	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
GWI30_16285	ENOG4105F5D	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
GWI30_16290	ENOG4106I92	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
GWI30_16295	ENOG4108J5C	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
GWI30_16300	ENOG4105DWQ	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
GWI30_16305	ENOG4105M85	Bola protein
GWI30_16310	ENOG4105D8J	Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle (By similarity)
GWI30_16320	ENOG4108R5K	PPIases accelerate the folding of proteins (By similarity)
GWI30_16330	ENOG4105EYM	Major Facilitator superfamily
GWI30_16335	ENOG4105DRB	nucleoside-specific channel-forming protein
GWI30_16340	ENOG4108VPT	UPF0234 protein
GWI30_16345	ENOG4108JZF	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity)
GWI30_16350	ENOG4107S0N	DJ-1 family
GWI30_16360	ENOG4105F5W	AtP-binding protein
GWI30_16365	ENOG4105D70	Integrase catalytic subunit
GWI30_16420	ENOG4105CS6	Rhs element vgr protein
GWI30_16430	ENOG4108WC9	type VI secretion system effector, hcp1 family
GWI30_16435	ENOG4105VJY	transcriptional regulator
GWI30_16440	ENOG4105CHH	sulfate transporter
GWI30_16465	ENOG4105K89	arsenate reductase
GWI30_16470	ENOG4105D6J	arsenicaL-resistance protein
GWI30_16505	ENOG4105CMR	udp-glucose 4-epimerase
GWI30_16510	ENOG4105CJJ	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity)
GWI30_16515	ENOG4105EJ7	Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O (By similarity)
GWI30_16520	ENOG4108RMU	ferritin dps family protein
GWI30_16545	ENOG4105CV9	cyclopropane-fatty-acyl-phospholipid synthase
GWI30_16560	ENOG4107FW0	short-chain dehydrogenase reductase
GWI30_16570	ENOG4105CVP	deoxyribo-dipyrimidine photolyase
GWI30_16575	ENOG4108XDN	Transcriptional regulator
GWI30_16580	ENOG4107SEY	Conserved Protein
GWI30_16605	ENOG4105CQC	Prephenate dehydratase
GWI30_16630	ENOG4108KDD	Involved in the transport of maltose and maltodextrins (By similarity)
GWI30_16650	ENOG4108KDD	Involved in the transport of maltose and maltodextrins (By similarity)
GWI30_16655	ENOG4105CUK	Alpha-N-arabinofuranosidase (EC 3.2.1.55)
GWI30_16670	ENOG4105F0P	binding-protein-dependent transport systems inner membrane Component
GWI30_16690	ENOG4105ETE	Transcriptional regulator (LacI family
GWI30_16705	ENOG4105D8V	Glucose sorbosone dehydrogenase
GWI30_16715	ENOG4105MVE	transcriptional regulator
GWI30_16725	ENOG4105G63	Type III effector Hrp-dependent
GWI30_16730	ENOG4105FB2	class II Aldolase
GWI30_16735	ENOG4105QG4	Catalyzes the reversible isomerization between hydroxypyruvate and 2-hydroxy-3-oxopropanoate (also termed tartronate semialdehyde) (By similarity)
GWI30_16740	ENOG4105EXW	epimerase dehydratase
GWI30_16745	ENOG4105C6Z	Gluconate
GWI30_16755	ENOG4108W2P	Methyl-accepting chemotaxis
GWI30_16765	ENOG4105E1F	short-chain dehydrogenase reductase
GWI30_16790	ENOG4105CTD	carboxy-peptidase
GWI30_16810	ENOG4105XDF	Protein of unknown function (DUF1272)
GWI30_16820	ENOG4105CFP	Peptidase U32
GWI30_16830	ENOG4105N14	lysine exporter protein LysE YggA
GWI30_16840	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
GWI30_16865	ENOG4108NJZ	Sensory box GGDEF EAL domain protein
GWI30_16875	ENOG4105DB1	molybdopterin oxidoreductase
GWI30_16880	ENOG4106WHD	Tetrathionate reductase
GWI30_16885	ENOG4105QA4	4Fe-4S Ferredoxin, iron-sulfur binding domain protein
GWI30_16890	ENOG4105BZU	Histidine kinase
GWI30_16895	ENOG4108ZXC	Two component transcriptional regulator, luxr family
GWI30_16900	ENOG4105EQ6	Hydrolyzes dipeptides containing N-terminal aspartate residues. May play a role in allowing the cell to use peptide aspartate to spare carbon otherwise required for the synthesis of the aspartate family of amino acids (By similarity)
GWI30_16920	ENOG410600T	transposase
GWI30_16935	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
GWI30_16940	ENOG4105CDU	Replicative dna helicase
GWI30_16945	ENOG4105CDU	Replicative dna helicase
GWI30_16985	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
GWI30_16990	ENOG4108V1T	peptidylprolyl cis-trans isomerase
GWI30_17005	ENOG4108YZY	peptidylprolyl cis-trans isomerase
GWI30_17010	ENOG4105VKU	nucleicacid-binding protein
GWI30_17025	ENOG4105DNZ	Alpha Beta Hydrolase
GWI30_17035	ENOG4105YP7	UPF0270 protein
GWI30_17040	ENOG4105CJE	phosphoribulokinase (EC 2.7.1.19)
GWI30_17055	ENOG4108UKZ	OsmC family
GWI30_17060	ENOG4107RYR	Transcriptional regulator, Crp Fnr family
GWI30_17075	ENOG4108MA4	Peptidase M66
GWI30_17090	ENOG4105BZU	Histidine kinase
GWI30_17095	ENOG4105D8G	Major Facilitator superfamily
GWI30_17130	ENOG4105PYN	Pyridoxamine 5-phosphate oxidase-related
GWI30_17135	ENOG41090JE	Utilization Protein
GWI30_17145	ENOG4105EHG	Permease protein
GWI30_17160	ENOG4105C6Y	Udp-glucose 6-dehydrogenase
GWI30_17170	ENOG4105SA9	Catalyzes the transfer of the L-Ara4N moiety of the glycolipid undecaprenyl phosphate-alpha-L-Ara4N to lipid A. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides (By similarity)
GWI30_17180	ENOG4105CKK	Glycosyl transferase, family 2
GWI30_17185	ENOG4105E4C	Lytic transglycosylase catalytic
GWI30_17190	ENOG4105C5H	ABC transporter
GWI30_17200	ENOG4105C7N	Xanthine uracil vitamin C permease
GWI30_17205	ENOG41066UG	Regulatory DnaK co-chaperone. Direct interaction between DnaK and DjlA is needed for the induction of the wcaABCDE operon, involved in the synthesis of a colanic acid polysaccharide capsule, possibly through activation of the RcsB RcsC phosphotransfer signaling pathway. The colanic acid capsule may help the bacterium survive conditions outside the host (By similarity)
GWI30_17210	ENOG4108S0S	Nucleotidyl transferase
GWI30_17215	ENOG4105EHM	Aminoglycoside phosphotransferase
GWI30_17220	ENOG4105E7H	involved in the assembly of LPS in the outer leaflet of the outer membrane. Determines N-hexane tolerance and is involved in outer membrane permeability. Essential for envelope biogenesis (By similarity)
GWI30_17230	ENOG4105CEZ	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) (By similarity)
GWI30_17235	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
GWI30_17245	ENOG4105DDT	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP (By similarity)
GWI30_17265	ENOG4105DEN	Luciferase family
GWI30_17270	ENOG4108ESY	Metal dependent phosphohydrolase
GWI30_17275	ENOG4105DWD	nucleoside recognition domain protein
GWI30_17280	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
GWI30_17285	ENOG4105K46	50S ribosomal protein l27
GWI30_17290	ENOG4105KK9	This protein binds to 23S rRNA in the presence of protein L20 (By similarity)
GWI30_17295	ENOG4105EAH	synthase
GWI30_17305	ENOG4105EPW	hflc protein
GWI30_17310	ENOG4107QJR	hflk protein
GWI30_17315	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
GWI30_17320	ENOG4105KW8	RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity)
GWI30_17325	ENOG4105DKX	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity)
GWI30_17330	ENOG4105DC6	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity)
GWI30_17335	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
GWI30_17340	ENOG4105K8N	protein family UPF0079, ATPase
GWI30_17345	ENOG4105DR1	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)
GWI30_17365	ENOG4108JEI	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity)
GWI30_17370	ENOG4108UMI	ABC transporter, permease
GWI30_17375	ENOG4105D01	(LipO)protein
GWI30_17385	ENOG4105MDZ	Transcriptional activator rfaH
GWI30_17390	ENOG4105C8Q	Methyl-accepting chemotaxis
GWI30_17400	ENOG4105BZU	Histidine kinase
GWI30_17415	ENOG410600T	transposase
GWI30_17425	ENOG4105F2I	Transposase
GWI30_17430	ENOG410600T	transposase
GWI30_17445	ENOG4105CK7	Sodium proline symporter
GWI30_17450	ENOG4107N1Q	ErfK YbiS YcfS YnhG family protein
GWI30_17455	ENOG4105CUY	Mechanosensitive ion channel
GWI30_17465	ENOG4105XEP	YhcH YjgK YiaL family protein
GWI30_17495	ENOG410600T	transposase
GWI30_17505	ENOG4105EV4	Multidrug resistance protein mdtH
GWI30_17525	ENOG4105D0C	transport protein
GWI30_17530	ENOG4108UT2	hemolysin iii
GWI30_17535	ENOG4105DY8	decarboxylase
GWI30_17540	ENOG4107835	probably involved in intracellular septation (By similarity)
GWI30_17545	ENOG4105K9H	YciI-like protein
GWI30_17550	ENOG4108RNI	3'(2')5'-bisphosphate nucleotidase
GWI30_17555	ENOG41083P1	competence protein ComEA helix-hairpin-helix repeat protein
GWI30_17560	ENOG4105C3Y	UTP-glucose-1-phosphate uridylyltransferase
GWI30_17565	ENOG4105DUX	Transporter
GWI30_17570	ENOG4105I93	response regulator
GWI30_17600	ENOG4107V40	secretion protein, HlyD family
GWI30_17610	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
GWI30_17615	ENOG4105VY0	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters (By similarity)
GWI30_17620	ENOG4108NIW	Leucine export protein LeuE
GWI30_17655	ENOG4108YX9	iron--sulfur cluster insertion protein erpA
GWI30_17670	ENOG4105CDM	Glutamate-1-semialdehyde aminotransferase
GWI30_17690	ENOG41076MN	Phosphoesterase, PA-phosphatase related
GWI30_17700	ENOG4105EGI	Transcriptional regulator
GWI30_17705	ENOG41090TI	Catalyzes the excretion of spermidine (By similarity)
GWI30_17710	ENOG4108ZBZ	Catalyzes the excretion of spermidine (By similarity)
GWI30_17715	ENOG4108YZK	glyoxalase bleomycin resistance protein dioxygenase
GWI30_17720	ENOG4105BZ4	penicillin-binding protein
GWI30_17725	ENOG4105CQ7	ATP-dependent helicase
GWI30_17730	ENOG4108784	2'-5' rna ligase
GWI30_17735	ENOG4105PW4	Sugar fermentation stimulation protein homolog
GWI30_17745	ENOG4106F3G	Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon (By similarity)
GWI30_17750	ENOG4105DJ0	Poly(A) Polymerase
GWI30_17755	ENOG4105K8U	2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
GWI30_17760	ENOG4105CCG	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is tranferred onto alpha-ketoisovalerate to form ketopantoate (By similarity)
GWI30_17765	ENOG4108IAA	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate (By similarity)
GWI30_17775	ENOG4105E3A	(ABC) transporter
GWI30_17780	ENOG4105DA5	(ABC) transporter
GWI30_17785	ENOG4108UGV	hypoxanthine phosphoribosyltransferase
GWI30_17800	ENOG410630P	Transcriptional regulator
GWI30_17805	ENOG4108UMA	3-octaprenyl-4-hydroxybenzoate carboxy-lyase
GWI30_17810	ENOG4105DFU	Cell wall formation (By similarity)
GWI30_17815	ENOG4105F0N	pyrophosphate phospho-hydrolase
GWI30_17830	ENOG4108UUE	Transcriptional regulator
GWI30_17865	ENOG4107RHT	methyl-accepting chemotaxis sensory transducer with Pas Pac sensor
GWI30_17885	ENOG4108I67	Catalyzes the synthesis of activated sulfate (By similarity)
GWI30_17895	ENOG4105C3T	may be the GTPase, regulating ATP sulfurylase activity (By similarity)
GWI30_17910	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
GWI30_17915	ENOG4107QX8	SPFH domain, Band 7 family protein
GWI30_17920	ENOG4105G5H	Membrane
GWI30_17930	ENOG4105D9R	oxidoreductase
GWI30_17940	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
GWI30_17945	ENOG4105CSA	Coproporphyrinogen iii oxidase
GWI30_17970	ENOG4105DC1	bifunctional purine biosynthesis protein purh
GWI30_17975	ENOG4105C12	Phosphoribosylglycinamide synthetase
GWI30_18000	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
GWI30_18005	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
GWI30_18010	ENOG4105KTH	gatB Yqey
GWI30_18015	ENOG4105VCC	30S ribosomal protein S21
GWI30_18020	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
GWI30_18035	ENOG4105F2I	Transposase
GWI30_18040	ENOG4108K5P	(LipO)protein
GWI30_18045	ENOG4108UM1	dedA family
GWI30_18050	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
GWI30_18055	ENOG4105CV2	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates (By similarity)
GWI30_18060	ENOG4106NZV	Responsible for synthesis of pseudouridine from uracil- 13 in transfer RNAs (By similarity)
GWI30_18065	ENOG4108UH8	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (By similarity)
GWI30_18070	ENOG4105CE5	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) (By similarity)
GWI30_18075	ENOG4105XX3	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity)
GWI30_18080	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
GWI30_18085	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
GWI30_18090	ENOG4105DXN	mazG family
GWI30_18095	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
GWI30_18100	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
GWI30_18105	ENOG4105BZU	Histidine kinase
GWI30_18110	ENOG4108W15	Protein of unknown function (DUF1456)
GWI30_18115	ENOG4108VBV	N-Acetylmuramoyl-L-alanine amidase
GWI30_18120	ENOG4105CSZ	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate (By similarity)
GWI30_18125	ENOG41071DT	Involved in DNA repair and RecF pathway recombination (By similarity)
GWI30_18140	ENOG4105C3F	Signal peptidase i
GWI30_18145	ENOG4105C4S	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity)
GWI30_18165	ENOG4105EMN	RNA polymerase sigma factor
GWI30_18170	ENOG4108IYU	L-aspartate oxidase
GWI30_18205	ENOG4105VF7	tolerance protein
GWI30_18210	ENOG4105CSG	Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps (By similarity)
GWI30_18220	ENOG4105CJP	fad dependent oxidoreductase
GWI30_18225	ENOG4105D2N	Aldolase
GWI30_18230	ENOG4105BZA	Phosphoglycerate kinase
GWI30_18235	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
GWI30_18240	ENOG4105DKQ	ROK family
GWI30_18245	ENOG4105CFZ	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III (By similarity)
GWI30_18250	ENOG4105E09	nadh pyrophosphatase
GWI30_18255	ENOG4106MWK	domain protein
GWI30_18260	ENOG4105EYW	Ion transport protein
GWI30_18265	ENOG4108NVR	Methyl-accepting chemotaxis
GWI30_18275	ENOG4105CE6	Adenylation and deadenylation of glutamate--ammonia ligase (By similarity)
GWI30_18280	ENOG4105CYX	Short-chain dehydrogenase reductase Sdr
GWI30_18295	ENOG4107PU6	Membrane
GWI30_18300	ENOG4108UW5	maltose o-acetyltransferase
GWI30_18325	ENOG4105F2I	Transposase
GWI30_18330	ENOG4105CH7	arginosuccinase
GWI30_18335	ENOG4105CDH	Citrulline--aspartate ligase
GWI30_18345	ENOG4105CAS	nag kinase
GWI30_18350	ENOG4105C0N	N-acetylglutamate semialdehyde dehydrogenase
GWI30_18360	ENOG4105CCA	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle (By similarity)
GWI30_18365	ENOG4105BZU	Histidine kinase
GWI30_18370	ENOG4108Z66	YbaK ebsC protein
GWI30_18410	ENOG4105CMU	LysR family (Transcriptional regulator
GWI30_18420	ENOG41067MG	lrgb family
GWI30_18425	ENOG4105CFH	Aspartokinase
GWI30_18430	ENOG4105C28	cystathionine
GWI30_18435	ENOG4105GGQ	This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis (By similarity)
GWI30_18445	ENOG4108Z7R	Chaperone CsaA
GWI30_18450	ENOG4105C44	Serine transporter
GWI30_18455	ENOG4108RNI	3'(2')5'-bisphosphate nucleotidase
GWI30_18460	ENOG4107RK2	ADP-ribose diphosphatase NudE
GWI30_18465	ENOG4107Y3D	HAD-superfamily hydrolase subfamily IA variant 3
GWI30_18475	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
GWI30_18480	ENOG4108UDW	Transcriptional regulator, luxr family
GWI30_18525	ENOG4108VAU	general secretion pathway protein G
GWI30_18530	ENOG4105D7Q	type ii secretion system
GWI30_18535	ENOG4107QHF	type ii secretion system protein e
GWI30_18540	ENOG4105GVR	general secretion pathway protein D
GWI30_18550	ENOG4105VEJ	Heat shock protein
GWI30_18555	ENOG4105F4C	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress (By similarity)
GWI30_18560	ENOG4105DJ1	Phosphoenolpyruvate Carboxylase
GWI30_18580	ENOG4108XTF	Outer Membrane Lipoprotein
GWI30_18590	ENOG4107IX6	phosphate transport regulator
GWI30_18595	ENOG4105CJ3	phosphate transporter
GWI30_18600	ENOG4105D4J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
GWI30_18615	ENOG4105CEN	a g-specific adenine glycosylase
GWI30_18620	ENOG4105KMG	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes (By similarity)
GWI30_18625	ENOG4106S48	Murein-degrading enzyme. May play a role in recycling of muropeptides during cell elongation and or cell division
GWI30_18640	ENOG4105UYK	outer membrane protein a
GWI30_18645	ENOG4108Q2G	(LipO)protein
GWI30_18650	ENOG4105DY2	Paraquat-inducible protein b
GWI30_18655	ENOG4105F1S	paraquat-inducible protein a
GWI30_18660	ENOG4105KW8	RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity)
GWI30_18665	ENOG4107VXZ	Hydrolase
GWI30_18675	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
GWI30_18680	ENOG4105D8J	Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle (By similarity)
GWI30_18685	ENOG4107QQ4	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans (By similarity)
GWI30_18690	ENOG4105CXW	Synthesizes alpha-1,4-glucan chains using ADP-glucose (By similarity)
GWI30_18730	ENOG4105DFD	Na H antiporter
GWI30_18735	ENOG4108M0I	Transcriptional regulator
GWI30_18740	ENOG4107TYH	extracellular solute-binding protein family 1
GWI30_18745	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
GWI30_18750	ENOG4105D81	ABC transporter, permease
GWI30_18755	ENOG4105NRK	Binding-protein-dependent transport systems, inner membrane component
GWI30_18760	ENOG4105C26	Dehydrogenase
GWI30_18765	ENOG4105F1R	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group (By similarity)
GWI30_18770	ENOG4107VFP	cytochrome oxidase assembly
GWI30_18790	ENOG4107QS1	Cytochrome C Oxidase, Subunit III
GWI30_18795	ENOG4105FT1	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I (By similarity)
GWI30_18800	ENOG4105BZ9	Cytochrome C oxidase, subunit I
GWI30_18810	ENOG4105E0I	Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of tRNA(Met), by using acetyl-CoA as an acetyl donor and ATP (or GTP) (By similarity)
GWI30_18825	ENOG4108UQY	Iron-storage protein
GWI30_18830	ENOG4108Z5K	methylglyoxal synthase
GWI30_18845	ENOG4105HDK	L-asparaginase
GWI30_18855	ENOG4105DDV	Transcriptional regulator (LacI family
GWI30_18865	ENOG4105DKQ	ROK family
GWI30_18870	ENOG4105VCP	PTS System
GWI30_18875	ENOG4105CS2	ec 3.2.1.21
GWI30_18880	ENOG4105CK1	PTS System
GWI30_18885	ENOG4105VZJ	PTS System
GWI30_18890	ENOG4105CK1	PTS System
GWI30_18900	ENOG4105D4X	repressor
GWI30_18905	ENOG4105C5Y	PTS System
GWI30_18910	ENOG4105CG3	alpha amylase, catalytic region
GWI30_18915	ENOG4108UW5	maltose o-acetyltransferase
GWI30_18955	ENOG4105UYK	outer membrane protein a
GWI30_18970	ENOG4105F5W	AtP-binding protein
GWI30_18975	ENOG4105D70	Integrase catalytic subunit
GWI30_19005	ENOG4105K7Z	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP (By similarity)
GWI30_19010	ENOG4107ZVW	dihydroneopterin aldolase
GWI30_19015	ENOG4105K8U	2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
GWI30_19025	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
GWI30_19030	ENOG4105CKI	cobalamin synthesis protein
GWI30_19040	ENOG4105E82	cytochrome subunit of dehydrogenase
GWI30_19050	ENOG4105BZU	Histidine kinase
GWI30_19055	ENOG4107QIJ	Aconitate hydratase 2
GWI30_19060	ENOG4105D78	K07001 NTE family protein
GWI30_19065	ENOG41069D7	Methyl-accepting chemotaxis
GWI30_19080	ENOG4105BZU	Histidine kinase
GWI30_19085	ENOG4107QN2	dihydrolipoyl dehydrogenase
GWI30_19090	ENOG4107QSN	dihydrolipoamide acetyltransferase
GWI30_19095	ENOG4105DAQ	Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) (By similarity)
GWI30_19100	ENOG41073TP	transcriptional regulator
GWI30_19115	ENOG4105D18	nicotinate-nucleotide pyrophosphorylase
GWI30_19125	ENOG4107QHF	type ii secretion system protein e
GWI30_19130	ENOG4105D7Q	type ii secretion system
GWI30_19135	ENOG4105EHH	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue (By similarity)
GWI30_19145	ENOG4105DHA	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity (By similarity)
GWI30_19150	ENOG41067SF	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase (By similarity)
GWI30_19160	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
GWI30_19170	ENOG4105C7C	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
GWI30_19175	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
GWI30_19180	ENOG4105CIT	This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity)
GWI30_19185	ENOG4105K7E	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly (By similarity)
GWI30_19190	ENOG4105DFU	Cell wall formation (By similarity)
GWI30_19195	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
GWI30_19200	ENOG4105CNI	cell division protein FtsW
GWI30_19205	ENOG4105DMZ	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity)
GWI30_19210	ENOG4105CPY	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity)
GWI30_19215	ENOG4108EQQ	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein (By similarity)
GWI30_19220	ENOG4107EEN	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity)
GWI30_19225	ENOG4105CJN	penicillin-binding protein
GWI30_19230	ENOG41063Y6	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity)
GWI30_19235	ENOG4105CGJ	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity)
GWI30_19240	ENOG4108V6E	Cell division protein mraZ
GWI30_19250	ENOG4105CU0	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity)
GWI30_19255	ENOG4105E1C	Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1A (PBP1a) (By similarity)
GWI30_19260	ENOG41082RQ	UPF0102 protein
GWI30_19265	ENOG4105F55	Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate (By similarity)
GWI30_19270	ENOG4105W4M	Transport-associated protein
GWI30_19275	ENOG4105KB2	stringent starvation protein b
GWI30_19280	ENOG4107MKT	Stringent starvation protein a
GWI30_19285	ENOG4105EIX	cytochrome c1
GWI30_19290	ENOG4105DJ5	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
GWI30_19295	ENOG4108R5F	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
GWI30_19300	ENOG4108UJD	30S ribosomal protein S9
GWI30_19305	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
GWI30_19310	ENOG4105D6Z	AFG1 family ATPase
GWI30_19320	ENOG4105C0H	protease
GWI30_19325	ENOG4105C0H	protease
GWI30_19335	ENOG41080Z8	PHOSPHOCARRIER protein
GWI30_19340	ENOG4105C21	Displays ATPase and GTPase activities (By similarity)
GWI30_19345	ENOG4107RM2	PTS IIA-like nitrogen-regulatory protein PtsN
GWI30_19350	ENOG41080QH	sigma 54 modulation protein ribosomal protein S30EA
GWI30_19355	ENOG4105DTW	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
GWI30_19360	ENOG4108IUZ	ABC transporter
GWI30_19365	ENOG4105WI0	lipopolysaccharide transport periplasmic protein lptA
GWI30_19370	ENOG4108P1K	Required for the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane (By similarity)
GWI30_19380	ENOG4105C2X	Arabinose 5-phosphate isomerase
GWI30_19385	ENOG4105DHJ	ABC, transporter
GWI30_19390	ENOG4105CY3	ABC transporter, permease
GWI30_19395	ENOG4107PE3	Mammalian cell entry related domain protein
GWI30_19400	ENOG4105E3I	toluene tolerance
GWI30_19410	ENOG4105VFK	BolA family
GWI30_19415	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
GWI30_19420	ENOG4105CMS	peptidase U62, modulator of DNA gyrase
GWI30_19425	ENOG4105N42	UPF0307 protein
GWI30_19445	ENOG41090HJ	UPF0265 protein
GWI30_19475	ENOG4108JCI	Transcriptional regulator
GWI30_19480	ENOG4105DKK	Benzoate
GWI30_19490	ENOG4108YXU	transcriptional regulator AsnC family
GWI30_19500	ENOG4105CVG	Homoserine O-transsuccinylase
GWI30_19510	ENOG4108I62	cina-like protein
GWI30_19515	ENOG4107K5X	Membrane-bound metal-dependent hydrolase
GWI30_19525	ENOG410667J	hydrolase
GWI30_19530	ENOG4108Z86	Glutamine amidotransferase
GWI30_19540	ENOG4105DFC	had-superfamily hydrolase, subfamily ia, variant
GWI30_19545	ENOG4108IYS	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
GWI30_19555	ENOG4105E4Z	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan (By similarity)
GWI30_19560	ENOG4105CU5	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity)
GWI30_19570	ENOG4105XQ6	frataxin-like protein
GWI30_19575	ENOG4106CJB	Phospholipase Carboxylesterase
GWI30_19580	ENOG4107T0K	Adenylate cyclase
GWI30_19585	ENOG4105D6W	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity)
GWI30_19590	ENOG41076E6	Uroporphyrinogen-III Synthase
GWI30_19595	ENOG4105ECF	c-methyltransferase
GWI30_19600	ENOG410601J	HemY protein
GWI30_19605	ENOG4105KRS	Proteinase inhibitor
GWI30_19610	ENOG4105CBT	Fructose-1,6-bisphosphatase
GWI30_19615	ENOG4105FCK	Membrane
GWI30_19620	ENOG4108Z7F	N-acetyltransferase
GWI30_19640	ENOG4105KVH	Transcriptional regulator
GWI30_19645	ENOG4105N0V	mono-oxygenase ydhR
GWI30_19660	ENOG4108TPP	exopolysaccharide synthesis
GWI30_19665	ENOG4105BZU	Histidine kinase
GWI30_19685	ENOG4108WEF	Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1B (PBP1b) (By similarity)
GWI30_19690	ENOG4105F2I	Transposase
GWI30_19700	ENOG4105D41	biosynthesis protein thiH
GWI30_19705	ENOG4105CA8	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity)
GWI30_19715	ENOG4105D06	uba thif-type nad fad binding protein
GWI30_19720	ENOG4108UV6	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity)
GWI30_19725	ENOG4105CBF	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction (By similarity)
GWI30_19740	ENOG4105ETX	regulatoR
GWI30_19750	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
GWI30_19755	ENOG4105C3R	Methionine synthase
GWI30_19760	ENOG4105EEQ	Na H antiporter
GWI30_19770	ENOG4105KNA	-acetyltransferase
GWI30_19780	ENOG4105CGZ	zinc metallopeptidase
GWI30_19790	ENOG4105CSH	Transporter
GWI30_19805	ENOG4105D1U	peptidase U62 modulator of DNA gyrase
GWI30_19815	ENOG4105QD6	exported protein
GWI30_19820	ENOG4105C03	ribonuclease
GWI30_19825	ENOG4108Z03	MAF-like protein
GWI30_19830	ENOG4105VQ7	Rod shape-determining protein MreD
GWI30_19835	ENOG4105N3I	Involved in formation and maintenance of cell shape (By similarity)
GWI30_19880	ENOG4105X0D	Fimbrial protein
GWI30_19885	ENOG4108VAU	general secretion pathway protein G
GWI30_19900	ENOG4105D7Q	type ii secretion system
GWI30_19905	ENOG4107QHF	type ii secretion system protein e
GWI30_19950	ENOG41062P1	Diguanylate cyclase phosphodiesterase
GWI30_19960	ENOG4107XTP	(EAL) domain protein
GWI30_19965	ENOG4105EWV	Sodium calcium exchanger membrane region
GWI30_19970	ENOG4105C84	Histidine ammonia-lyase
GWI30_19975	ENOG4105CGP	Urocanate hydratase
GWI30_19980	ENOG41088SP	formiminoglutamate hydrolase
GWI30_19985	ENOG4105CI2	imidazolone-5-propionate hydrolase
GWI30_19990	ENOG4105CZE	histidine utilization repressor
GWI30_19995	ENOG41077A9	carbonic anhydrase
GWI30_20000	ENOG4105DEK	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
GWI30_20005	ENOG4105CRP	Part of the ABC transporter FtsEX involved in
GWI30_20010	ENOG4105CAK	Cell division ATP-binding protein ftsE
GWI30_20015	ENOG4105CCP	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
GWI30_20020	ENOG4106H78	methyltransferase
GWI30_20030	ENOG4108Y73	Membrane
GWI30_20035	ENOG4105EJ2	Transcriptional regulator
GWI30_20045	ENOG4107RZC	phospholipase d
GWI30_20050	ENOG4105CHQ	Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella (By similarity)
GWI30_20070	ENOG41076UM	multiple antibiotic resistance (MarC)-related protein
GWI30_20075	ENOG4105VVZ	metal-binding protein
GWI30_20090	ENOG4105JQN	Transcriptional regulator
GWI30_20105	ENOG4105VNT	transposase (IS4 family) protein
GWI30_20110	ENOG4107FS9	Membrane
GWI30_20135	ENOG4105CUG	Oligopeptidase b
GWI30_20150	ENOG4108K2R	Glutathione-regulated potassium-efflux system ancillary protein
GWI30_20205	ENOG4108ZI0	d,d-heptose 1,7-bisphosphate phosphatase
GWI30_20210	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
GWI30_20215	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
GWI30_20220	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
GWI30_20225	ENOG4108UKE	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity)
GWI30_20230	ENOG4105YKK	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions (By similarity)
GWI30_20245	ENOG4105KME	endoribonuclease L-psp
GWI30_20250	ENOG4105WWK	YheO domain protein
GWI30_20255	ENOG4105D27	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
GWI30_20260	ENOG4108IIJ	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
GWI30_20265	ENOG4105KBC	Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity)
GWI30_20270	ENOG4108VZM	50s ribosomal protein L10
GWI30_20275	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
GWI30_20280	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
GWI30_20285	ENOG4105E5V	Participates in transcription elongation, termination and antitermination (By similarity)
GWI30_20290	ENOG4105PM1	preprotein translocase subunit SecE
GWI30_20300	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
GWI30_20315	ENOG4105CS9	pantothenic acid kinase
GWI30_20320	ENOG4105HJX	Biotin- acetyl-CoA-carboxylase ligase
GWI30_20325	ENOG4105D4A	Cell wall formation (By similarity)
GWI30_20330	ENOG4107ZYR	domain protein
GWI30_20340	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
GWI30_20345	ENOG4105CUW	cytochrome C-TYPE protein
GWI30_20350	ENOG4107QY8	reductase
GWI30_20360	ENOG4105IFJ	Histidine kinase
GWI30_20365	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
GWI30_20380	ENOG4105DQ2	Is probably involved in the electron transfer between its heme and the molybdenum cofactor of the reductase catalytic subunit YedY (By similarity)
GWI30_20395	ENOG4108UQ5	membrane protein YcdZ
GWI30_20400	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
GWI30_20410	ENOG4107WP9	Histidine kinase
GWI30_20425	ENOG410642E	Short chain dehydrogenase
GWI30_20430	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
GWI30_20445	ENOG4108VVK	transcriptional Regulator, AsnC
GWI30_20450	ENOG4105CU9	asparagine synthetase A
GWI30_20455	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
GWI30_20460	ENOG4105DBW	Multi-copper polyphenol oxidoreductase laccase
GWI30_20465	ENOG4105C34	Pseudouridine synthase
GWI30_20470	ENOG4106SNF	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
GWI30_20475	ENOG4107QMW	pyridine nucleotide-disulfide oxidoreductase
GWI30_20480	ENOG4107R6U	sodium dicarboxylate symporter
GWI30_20485	ENOG4105CEM	UPF0597 protein
GWI30_20490	ENOG4105C15	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
GWI30_20495	ENOG4108IIE	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
GWI30_20500	ENOG4108I6A	alcohol dehydrogenase
GWI30_20505	ENOG4105CF7	AraC family transcriptional regulator
GWI30_20510	ENOG4105QNF	Outer membrane lipoprotein
GWI30_20525	ENOG4105DJ4	phosphatidylserine decarboxylase
GWI30_20540	ENOG4105CXT	aspartate transcarbamylase
GWI30_20545	ENOG4108R9M	Involved in allosteric regulation of aspartate carbamoyltransferase (By similarity)
GWI30_20550	ENOG410682Y	Regulates arginine biosynthesis genes (By similarity)
GWI30_20555	ENOG4105CSX	c4-dicarboxylate anaerobic carrier
GWI30_20560	ENOG4105DBV	ornithine carbamoyltransferase
GWI30_20565	ENOG4105C5B	carbamate kinase
GWI30_20580	ENOG4105C8Q	Methyl-accepting chemotaxis
GWI30_20590	ENOG4108HWV	)-transporter
GWI30_20605	ENOG4105CNT	hydrolase family 2
GWI30_20610	ENOG41060NJ	transcriptional regulator
GWI30_20615	ENOG4105CMR	udp-glucose 4-epimerase
GWI30_20620	ENOG4105F0Z	galactose-1-phosphate uridylyltransferase
GWI30_20625	ENOG4105CRD	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P) (By similarity)
GWI30_20630	ENOG4105ENN	converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose (By similarity)
GWI30_20635	ENOG4105CPC	Aldo Keto reductase
GWI30_20640	ENOG4105DWR	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity)
GWI30_20645	ENOG4108NIX	Factor ChrR
GWI30_20650	ENOG4105K6V	RNA polymerase
GWI30_20660	ENOG4105C75	arginyL-tRNA synthetase
GWI30_20670	ENOG4108R5P	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery (By similarity)
GWI30_20675	ENOG4105C4N	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis (By similarity)
GWI30_20695	ENOG4105D0S	secretion protein (HlyD
GWI30_20700	ENOG4105CJ1	ABC, transporter
GWI30_20705	ENOG4107QWP	ABC-2 type transporter
GWI30_20710	ENOG4107QWP	ABC-2 type transporter
GWI30_20715	ENOG4107QZF	nitrite reductase NADPH large subunit
GWI30_20720	ENOG4105WZK	nitrite reductase NADPH small subunit
GWI30_20725	ENOG4107V9H	nitrite transporter
GWI30_20730	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
GWI30_20735	ENOG4105CJW	magnesium transporter
GWI30_20740	ENOG4108YYX	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. Modulates RNA-binding and helicase activities of the degradosome (By similarity)
GWI30_20745	ENOG4105EX9	Membrane
GWI30_20755	ENOG4105CNG	UPF0061 protein
GWI30_20760	ENOG4105N7H	Cytochrome
GWI30_20765	ENOG4105C9U	ATP-dependent DNA helicase RecQ
GWI30_20770	ENOG4108VUY	thioesterase Superfamily protein
GWI30_20795	ENOG4108RPX	mosc domain containing protein
GWI30_20800	ENOG4105D38	putrescine abc transporter
GWI30_20805	ENOG4105F38	ABC transporter, permease
GWI30_20810	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
GWI30_20815	ENOG4108HM4	ABC transporter
GWI30_20825	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
GWI30_20830	ENOG4105CFQ	glutamine synthetase
GWI30_20835	ENOG4108V7X	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
GWI30_20850	ENOG4108RH0	Crea protein
GWI30_20855	ENOG4105C5I	Dehydrogenase
GWI30_20860	ENOG4105R8A	Heat shock protein
GWI30_20875	ENOG4107R28	alpha amylase, catalytic region
GWI30_20890	ENOG4107R9T	Catalyzes the formation of 5-methyl-uridine at position 54 (m5U54) in all tRNAs (By similarity)
GWI30_20895	ENOG4107EXC	regulatoR
GWI30_20900	ENOG4105JJR	Histidine kinase
GWI30_20915	ENOG4105C6K	Malic enzyme
GWI30_20920	ENOG4105CGD	Nad-dependent epimerase dehydratase
GWI30_20925	ENOG4105VFB	Binds the 23S rRNA (By similarity)
GWI30_20930	ENOG4105C25	Primosomal protein n'
GWI30_20935	ENOG4105UYK	outer membrane protein a
GWI30_20945	ENOG4105F2I	Transposase
GWI30_20950	ENOG4105C7B	Threonine dehydratase
GWI30_20955	ENOG4105C01	Dihydroxy-acid dehydratase
GWI30_20960	ENOG4105CM2	brancheD-chain amino acid aminotransferase
GWI30_20965	ENOG4105P3Y	Acetolactate synthase 2 regulatory subunit
GWI30_20980	ENOG4105C0P	Mg chelatase subunit ChlI
GWI30_20985	ENOG4106HNH	Acyl-transferase
GWI30_20990	ENOG4106HNH	Acyl-transferase
GWI30_20995	ENOG4105EWC	Purine nucleoside phosphorylase
GWI30_21005	ENOG4108RWI	nicotinamidase
GWI30_21010	ENOG4107RH7	Nicotinate phosphoribosyltransferase
GWI30_21015	ENOG4105EHI	Phosphonate ABC transporter, periplasmic
GWI30_21020	ENOG4108VA1	ABC transporter
GWI30_21025	ENOG4105S7S	phosphonate abc transporter
GWI30_21030	ENOG4108Z33	Thiol disulfide Interchange Protein
GWI30_21035	ENOG4105E27	serine threonine protein kinase
GWI30_21045	ENOG4105PC1	Conserved Protein
GWI30_21065	ENOG4107QP2	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
GWI30_21070	ENOG4105ED0	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates (By similarity)
GWI30_21075	ENOG4105DSJ	YicC domain protein
GWI30_21090	ENOG4105D8A	3-Deoxy-D-manno-octulosonic-acid transferase
GWI30_21095	ENOG4105XA0	heptosyltransferase ii
GWI30_21100	ENOG4106WTF	Glycosyl transferase, family 2
GWI30_21105	ENOG4105M5K	heptosyltransferase
GWI30_21110	ENOG4108ZEF	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity)
GWI30_21115	ENOG4108MJ5	VirK protein
GWI30_21120	ENOG4105ERD	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity)
GWI30_21130	ENOG4105W0E	50S ribosomal protein L33
GWI30_21135	ENOG4105KDC	50s ribosomal protein l28
GWI30_21140	ENOG4105W5Q	DNA repair protein (RadC
GWI30_21145	ENOG4105CJS	Phosphopantothenoylcysteine decarboxylase
GWI30_21150	ENOG4108Z1K	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA (By similarity)
GWI30_21155	ENOG4105EC0	Required for nucleoid occlusion (NO) phenomenon, which prevents Z-ring formation and cell division over the nucleoid. Acts as a DNA-associated cell division inhibitor that binds simultaneously chromosomal DNA and FtsZ, and disrupts the assembly of FtsZ polymers. SlmA-DNA-binding sequences (SBS) are dispersed on non-Ter regions of the chromosome, preventing FtsZ polymerization at these regions (By similarity)
GWI30_21160	ENOG4105D64	Mechanosensitive ion channel
GWI30_21170	ENOG4107QP8	phosphohexose isomerase
GWI30_21180	ENOG4105C6M	Alpha-keto-beta-hydroxylacyl reductoisomerase
GWI30_21185	ENOG4105EMY	transcriptional regulator
GWI30_21195	ENOG4105CD5	CoA-binding domain protein
GWI30_21225	ENOG4108RR8	protoporphyrinogen oxidase
GWI30_21230	ENOG4105D37	Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA (By similarity)
GWI30_21235	ENOG4108ZK7	protein family UPF0029, Impact, N-terminal protein
GWI30_21240	ENOG4105D9Y	Splits dipeptides with a prolyl residue in the C- terminal position (By similarity)
GWI30_21245	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
GWI30_21250	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
GWI30_21255	ENOG4105CHU	acetyl-coa acetyltransferase
GWI30_21265	ENOG4105E0F	Histidine kinase
GWI30_21270	ENOG4105T29	extracellular solute-binding protein
GWI30_21285	ENOG41082K8	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Interacts with IscS and stimulates its activity. Then, accepts a sulfur from IscS and transfers it in turn to TusD (By similarity)
GWI30_21290	ENOG4105M4H	endoribonuclease L-psp
GWI30_21295	ENOG4108ZG0	Ompa motb domain protein
GWI30_21325	ENOG4108R3E	Dna-3-methyladenine glycosylase i
GWI30_21330	ENOG4108HMW	glycyl-tRNA synthetase, alpha subunit
GWI30_21335	ENOG4105C38	Glycyl-tRNA synthetase beta subunit
GWI30_21350	ENOG4105CIC	tryptophan-specific transport protein
GWI30_21355	ENOG4105CIC	tryptophan-specific transport protein
GWI30_21360	ENOG4105F2I	Transposase
GWI30_21370	ENOG4105HEE	Binding Domain protein
GWI30_21380	ENOG4108EQM	faD-dependent pyridine nucleotide-disulfide oxidoreductase
GWI30_21385	ENOG4105CNW	domain protein
GWI30_21390	ENOG4108JUA	Transcriptional regulator
GWI30_21400	ENOG4105ETE	Transcriptional regulator (LacI family
GWI30_21405	ENOG4105CP9	extracellular ligand-binding receptor
GWI30_21410	ENOG4105C32	Amino acid ABC transporter (Permease)
GWI30_21415	ENOG4105CF8	branched-chain amino acid ABC transporter, permease
GWI30_21420	ENOG4105C0Z	ABC transporter
GWI30_21425	ENOG4108IV0	ABC, transporter
GWI30_21440	ENOG4105M78	Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide (By similarity)
GWI30_21455	ENOG4105W0Z	cytoplasmic protein
GWI30_21465	ENOG4107QK7	reductase
GWI30_21470	ENOG4105D3H	Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol (By similarity)
GWI30_21480	ENOG4105C4P	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity)
GWI30_21490	ENOG4105C1J	atp-dependent rna helicase
GWI30_21495	ENOG4105C9X	ppx gppa phosphatase
GWI30_21510	ENOG4105FFN	Specifically methylates the guanosine in position 1516 of 16S rRNA (By similarity)
GWI30_21515	ENOG4105BZU	Histidine kinase
GWI30_21520	ENOG4105DGW	oligopeptidase A
GWI30_21525	ENOG4105D52	delta-aminolevulinic acid dehydratase
GWI30_21530	ENOG4105F8V	Hydrolase, tatD family
GWI30_21535	ENOG4105DCX	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity)
GWI30_21540	ENOG4105X8U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation (By similarity)
GWI30_21545	ENOG4105WKS	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity)
GWI30_21550	ENOG4105CNK	Required, probably indirectly, for the hydroxylation of 2-octaprenylphenol to 2-octaprenyl-6-hydroxy-phenol, the fourth step in ubiquinone biosynthesis (By similarity)
GWI30_21555	ENOG4105JC1	sterol-binding domain protein
GWI30_21560	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
GWI30_21565	ENOG4105WMR	Protein CrcB homolog
GWI30_21570	ENOG4105DZC	cytosine deaminase
GWI30_21575	ENOG4105DQW	permease for cytosine purines, uracil, thiamine, allantoin
GWI30_21615	ENOG410822N	TonB family
GWI30_21620	ENOG4109015	Biopolymer transport protein exbD tolR
GWI30_21645	ENOG410600T	transposase
GWI30_21650	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
GWI30_21655	ENOG410804X	Transcriptional regulator
GWI30_21660	ENOG4105E3W	Two component transcriptional regulator (Winged helix family
GWI30_21665	ENOG4105EB3	Histidine kinase
GWI30_21675	ENOG4105CT7	inner membrane cred family protein
GWI30_21680	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
GWI30_21685	ENOG4105KNM	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
GWI30_21690	ENOG4105C4J	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity)
GWI30_21695	ENOG4105J80	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity)
GWI30_21700	ENOG4105CDG	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity)
GWI30_21705	ENOG4107S15	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
GWI30_21710	ENOG4107Z6K	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
GWI30_21715	ENOG4105KY6	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
GWI30_21720	ENOG4105EE4	it plays a direct role in the translocation of protons across the membrane (By similarity)
GWI30_21730	ENOG4105FA0	parb-like partition protein
GWI30_21735	ENOG4107QJE	Chromosome Partitioning Protein
GWI30_21740	ENOG4105D28	Specifically methylates the N7 position of a guanine in 16S rRNA (By similarity)
GWI30_21745	ENOG4107RE5	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity)
GWI30_21750	ENOG4105QTB	Flavodoxin
GWI30_21755	ENOG4105E0K	tonB-dependent siderophore receptor
GWI30_21760	ENOG4105IBP	Cyclic peptide transporter
GWI30_21765	ENOG4105E0A	ABC, transporter
GWI30_21770	ENOG4105J76	Periplasmic binding protein
GWI30_21775	ENOG4105S6R	Iron-hydroxamate transporter permease subunit
GWI30_21785	ENOG4105CAF	HipA N-terminal domain protein
GWI30_21805	ENOG4108F3G	Type I restriction-modification system, R subunit
GWI30_21825	ENOG410600T	transposase
GWI30_21855	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
GWI30_21860	ENOG4105C1H	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity)
GWI30_21865	ENOG4105DHW	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
GWI30_21870	ENOG4105VAS	Could be involved in insertion of integral membrane proteins into the membrane (By similarity)
GWI30_21875	ENOG4105NVJ	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme (By similarity)
GWI30_21880	ENOG4105VG0	50S ribosomal protein l34
GWI30_21885	ENOG4105CDA	abc transporter atp-binding protein
GWI30_21890	ENOG4105E5Q	amino acid AbC transporter
GWI30_21895	ENOG4105EAB	amino acid AbC transporter
GWI30_21955	ENOG410600T	transposase
GWI30_21965	ENOG4107R3N	Filamentation induced by cAMP protein fic
GWI30_21990	ENOG4105D7V	transposase
GWI30_22000	ENOG4105C4R	Atp-dependent dna helicase
GWI30_22055	ENOG410600T	transposase
GWI30_22100	ENOG41065RQ	ADP-ribosylation crystallin J1
GWI30_22105	ENOG41065RQ	ADP-ribosylation crystallin J1
GWI30_22125	ENOG4105KT5	UmuD protein
GWI30_22130	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
GWI30_22135	ENOG4108UUM	single-stranded DNA-binding protein
GWI30_22145	ENOG4105DVT	helicase
GWI30_22155	ENOG4105D70	Integrase catalytic subunit
GWI30_22160	ENOG4105F5W	AtP-binding protein
GWI30_22165	ENOG4105D5G	Transposase
GWI30_22170	ENOG410600T	transposase
GWI30_22190	ENOG4105DYN	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. May be involved in the integration of spacer DNA into the CRISPR cassette (By similarity)
GWI30_22195	ENOG41063ZP	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease (By similarity)
GWI30_22290	ENOG4105D7V	transposase
GWI30_22305	ENOG4105KT5	UmuD protein
GWI30_22310	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
GWI30_22375	ENOG4105D7V	transposase
GWI30_22445	ENOG4105C0D	helicase
GWI30_22460	ENOG4107QMH	DNA methylase
GWI30_22465	ENOG4107QMH	DNA methylase
GWI30_22485	ENOG4105D5G	Transposase
GWI30_22515	ENOG410635M	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein (By similarity)
GWI30_22520	ENOG4108RW0	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
GWI30_22550	ENOG4105VYW	UPF0251 protein
GWI30_22605	ENOG4105W2W	Cytotoxic translational repressor of toxin-antitoxin stability system
GWI30_22630	ENOG4105D7V	transposase
GWI30_22690	ENOG4105D7V	transposase
GWI30_22725	ENOG4108UUM	single-stranded DNA-binding protein
GWI30_22730	ENOG4105D7V	transposase
GWI30_22750	ENOG4105D7V	transposase
GWI30_22825	ENOG4105D7V	transposase
GWI30_22855	ENOG4105D7V	transposase
GWI30_22945	ENOG410600T	transposase
GWI30_22955	ENOG4105BZU	Histidine kinase
GWI30_22975	ENOG410600T	transposase
GWI30_22995	ENOG4105EQR	Transposase IS116 IS110 IS902
GWI30_23015	ENOG4105VUN	Transcriptional regulator
GWI30_23020	ENOG4108BUD	transposase
GWI30_23040	ENOG4108BUD	transposase
GWI30_23055	ENOG4105I1F	Resistance protein
GWI30_23085	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
GWI30_23095	ENOG4105D70	Integrase catalytic subunit
GWI30_23100	ENOG4105F5W	AtP-binding protein
GWI30_23110	ENOG410600T	transposase
GWI30_23125	ENOG4108X73	DNA- binding protein
GWI30_23145	ENOG4105D7V	transposase
GWI30_23155	ENOG4105D5G	Transposase
GWI30_23190	ENOG4105DFS	Conserved Protein
GWI30_23290	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
GWI30_23305	ENOG4105EC0	Required for nucleoid occlusion (NO) phenomenon, which prevents Z-ring formation and cell division over the nucleoid. Acts as a DNA-associated cell division inhibitor that binds simultaneously chromosomal DNA and FtsZ, and disrupts the assembly of FtsZ polymers. SlmA-DNA-binding sequences (SBS) are dispersed on non-Ter regions of the chromosome, preventing FtsZ polymerization at these regions (By similarity)
GWI30_23330	ENOG4105C26	Dehydrogenase
GWI30_23345	ENOG4105K4U	addiction module toxin, RelE StbE family
GWI30_23365	ENOG4108NSC	Pfam:DUF88