locus-tag	class	description
GWI30_00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
GWI30_00010	COG0592	DNA-directed DNA polymerase activity
GWI30_00020	COG0187	DNA topoisomerase II activity
GWI30_00030	COG2378	regulation of single-species biofilm formation
GWI30_00040	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
GWI30_00045	COG0071	Belongs to the small heat shock protein (HSP20) family
GWI30_00050	COG0071	Belongs to the small heat shock protein (HSP20) family
GWI30_00055	COG3977	Valine--pyruvate aminotransferase
GWI30_00070	COG2814	Major facilitator Superfamily
GWI30_00075	COG0745	RESPONSE REGULATOR receiver
GWI30_00080	COG2205	protein histidine kinase activity
GWI30_00105	COG1733	regulation of RNA biosynthetic process
GWI30_00110	COG2267	carboxylic ester hydrolase activity
GWI30_00115	COG0604	alcohol dehydrogenase
GWI30_00125	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
GWI30_00130	COG4191	Histidine kinase
GWI30_00130	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GWI30_00135	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
GWI30_00140	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GWI30_00145	COG1309	transcriptional regulator
GWI30_00175	COG0561	phosphatase activity
GWI30_00180	COG2267	carboxylic ester hydrolase activity
GWI30_00185	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
GWI30_00195	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
GWI30_00200	COG1758	RNA polymerase activity
GWI30_00210	COG0859	PFAM glycosyl transferase family 9
GWI30_00255	COG0589	response to stress
GWI30_00260	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
GWI30_00265	COG3706	GGDEF domain
GWI30_00270	COG1528	Iron-storage protein
GWI30_00275	COG2081	HI0933 family
GWI30_00280	COG2223	nitrite transmembrane transporter activity
GWI30_00300	COG3039	Transposase
GWI30_00325	COG3275	phosphorelay sensor kinase activity
GWI30_00330	COG3279	Response regulator of the LytR AlgR family
GWI30_00335	COG2223	nitrite transmembrane transporter activity
GWI30_00340	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
GWI30_00345	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
GWI30_00350	COG4206	TonB-dependent receptor
GWI30_00355	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
GWI30_00390	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
GWI30_00395	COG2166	iron-sulfur cluster assembly
GWI30_00400	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
GWI30_00405	COG0210	DNA helicase
GWI30_00410	COG5001	Diguanylate cyclase
GWI30_00410	COG3300	MHYT domain
GWI30_00420	COG1063	alcohol dehydrogenase
GWI30_00435	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GWI30_00440	COG0438	transferase activity, transferring glycosyl groups
GWI30_00445	COG3307	-O-antigen
GWI30_00460	COG5433	transposase activity
GWI30_00485	COG0604	alcohol dehydrogenase
GWI30_00500	COG1580	Controls the rotational direction of flagella during chemotaxis
GWI30_00505	COG3161	chorismate lyase activity
GWI30_00510	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
GWI30_00520	COG2937	Belongs to the GPAT DAPAT family
GWI30_00525	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
GWI30_00540	COG0534	Mate efflux family protein
GWI30_00545	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
GWI30_00550	COG2205	protein histidine kinase activity
GWI30_00555	COG0745	RESPONSE REGULATOR receiver
GWI30_00565	COG1045	serine acetyltransferase
GWI30_00575	COG3074	FtsZ-dependent cytokinesis
GWI30_00580	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
GWI30_00585	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
GWI30_00585	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
GWI30_00590	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
GWI30_00625	COG1609	Transcriptional regulator
GWI30_00630	COG4584	PFAM Integrase catalytic
GWI30_00635	COG1484	DNA-dependent DNA replication
GWI30_00640	COG3250	beta-galactosidase activity
GWI30_00645	COG2731	YhcH YjgK YiaL family protein
GWI30_00650	COG0531	amino acid
GWI30_00655	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GWI30_00660	COG0531	amino acid
GWI30_00665	COG0385	Bile acid
GWI30_00670	COG1262	PFAM Formylglycine-generating sulfatase enzyme
GWI30_00690	COG0583	DNA-binding transcription factor activity
GWI30_00720	COG0210	DNA helicase
GWI30_00725	COG3039	Transposase
GWI30_00730	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
GWI30_00765	COG2391	methyltransferase activity
GWI30_00770	COG1280	lysine exporter protein (LysE YggA)
GWI30_00780	COG2962	Rard protein
GWI30_00790	COG1012	belongs to the aldehyde dehydrogenase family
GWI30_00795	COG1396	sequence-specific DNA binding
GWI30_00810	COG0518	GMP synthase (glutamine-hydrolyzing) activity
GWI30_00810	COG0519	Catalyzes the synthesis of GMP from XMP
GWI30_00820	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GWI30_00840	COG1322	Protein conserved in bacteria
GWI30_00845	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
GWI30_00850	COG0569	domain protein
GWI30_00855	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
GWI30_00855	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
GWI30_00860	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
GWI30_00865	COG0242	peptide deformylase activity
GWI30_00875	COG0758	DNA mediated transformation
GWI30_00880	COG2922	Belongs to the Smg family
GWI30_00885	COG0551	DNA topoisomerase type I activity
GWI30_00890	COG0009	L-threonylcarbamoyladenylate synthase
GWI30_00895	COG0408	coproporphyrinogen oxidase activity
GWI30_00900	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
GWI30_00905	COG0218	Necessary for normal cell division and for the maintenance of normal septation
GWI30_00915	COG3078	GTPase activator activity
GWI30_00925	COG0635	Involved in the biosynthesis of porphyrin-containing compound
GWI30_00930	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
GWI30_00940	COG3852	Histidine kinase
GWI30_00950	COG0174	glutamine synthetase
GWI30_00960	COG1295	ribonuclease BN
GWI30_00965	COG1490	D-aminoacyl-tRNA deacylase activity
GWI30_00975	COG0456	acetyltransferase
GWI30_00985	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
GWI30_00990	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
GWI30_00995	COG2610	gluconate transmembrane transporter activity
GWI30_01000	COG3265	gluconokinase activity
GWI30_01005	COG0129	dihydroxy-acid dehydratase activity
GWI30_01010	COG0800	Aldolase
GWI30_01015	COG1609	Transcriptional regulator
GWI30_01025	COG4942	peptidase
GWI30_01030	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
GWI30_01035	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
GWI30_01040	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
GWI30_01045	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
GWI30_01050	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
GWI30_01050	COG0316	Belongs to the HesB IscA family
GWI30_01055	COG1040	competence protein
GWI30_01060	COG0596	Alpha beta hydrolase
GWI30_01075	COG2183	response to ionizing radiation
GWI30_01080	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
GWI30_01085	COG0745	RESPONSE REGULATOR receiver
GWI30_01090	COG2205	protein histidine kinase activity
GWI30_01100	COG0051	transcription antitermination factor activity, RNA binding
GWI30_01105	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
GWI30_01110	COG0088	Forms part of the polypeptide exit tunnel
GWI30_01115	COG0089	rRNA binding
GWI30_01120	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
GWI30_01125	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
GWI30_01130	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
GWI30_01135	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
GWI30_01140	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
GWI30_01145	COG0255	Belongs to the universal ribosomal protein uL29 family
GWI30_01150	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
GWI30_01155	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
GWI30_01160	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
GWI30_01165	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
GWI30_01170	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
GWI30_01175	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
GWI30_01180	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
GWI30_01185	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
GWI30_01190	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
GWI30_01195	COG1841	ribosomal large subunit assembly
GWI30_01200	COG0200	Binds to the 23S rRNA
GWI30_01205	COG0201	protein transport
GWI30_01210	COG0257	Belongs to the bacterial ribosomal protein bL36 family
GWI30_01215	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
GWI30_01220	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
GWI30_01225	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
GWI30_01230	COG0202	RNA polymerase activity
GWI30_01235	COG0203	ribosomal protein L17
GWI30_01275	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
GWI30_01280	COG2252	PERMEase
GWI30_01290	COG2376	Dihydroxyacetone kinase
GWI30_01295	COG1461	Dihydroxyacetone kinase
GWI30_01305	COG3284	Transcriptional regulator
GWI30_01315	COG0628	permease
GWI30_01340	COG0753	catalase activity
GWI30_01345	COG0454	-acetyltransferase
GWI30_01345	COG0456	acetyltransferase
GWI30_01350	COG2207	Transcriptional regulator
GWI30_01375	COG3842	ATPase activity
GWI30_01385	COG1176	ABC-type spermidine putrescine transport system, permease component I
GWI30_01410	COG0583	DNA-binding transcription factor activity
GWI30_01420	COG1741	Belongs to the pirin family
GWI30_01425	COG2259	Doxx family
GWI30_01430	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
GWI30_01435	COG1074	ATP-dependent DNA helicase activity
GWI30_01440	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
GWI30_01445	COG3039	Transposase
GWI30_01450	COG0346	lactoylglutathione lyase activity
GWI30_01460	COG0004	ammonium transporteR
GWI30_01465	COG0347	Belongs to the P(II) protein family
GWI30_01470	COG3706	GGDEF domain
GWI30_01490	COG0745	RESPONSE REGULATOR receiver
GWI30_01495	COG2205	protein histidine kinase activity
GWI30_01500	COG1278	Cold shock
GWI30_01525	COG2197	response regulator
GWI30_01530	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
GWI30_01535	COG3039	Transposase
GWI30_01540	COG3047	cAMP biosynthetic process
GWI30_01565	COG1368	sulfuric ester hydrolase activity
GWI30_01595	COG4221	oxidoreductase activity
GWI30_01610	COG1979	alcohol dehydrogenase
GWI30_01620	COG2873	o-acetylhomoserine
GWI30_01650	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
GWI30_01660	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
GWI30_01665	COG2949	membrane
GWI30_01675	COG0318	PFAM AMP-dependent synthetase and ligase
GWI30_01680	COG1441	menaquinone biosynthetic process
GWI30_01685	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
GWI30_01690	COG0596	Alpha beta hydrolase
GWI30_01695	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
GWI30_01700	COG1169	isochorismate synthase
GWI30_01705	COG1575	Belongs to the MenA family. Type 1 subfamily
GWI30_01730	COG0513	Belongs to the DEAD box helicase family
GWI30_01740	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
GWI30_01755	COG1671	Belongs to the UPF0178 family
GWI30_01780	COG3722	fumarate hydratase activity
GWI30_01785	COG0246	Mannitol dehydrogenase
GWI30_01790	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
GWI30_01790	COG2213	PTS system mannitol-specific
GWI30_01795	COG4776	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction
GWI30_01810	COG2771	luxR family
GWI30_01825	COG1560	Kdo2-lipid A biosynthetic process
GWI30_01830	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
GWI30_01830	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
GWI30_01835	COG1538	Outer membrane efflux protein
GWI30_01840	COG0494	nUDIX hydrolase
GWI30_01845	COG3151	Protein conserved in bacteria
GWI30_01855	COG3150	esterase
GWI30_01860	COG1051	belongs to the nudix hydrolase family
GWI30_01890	COG3039	Transposase
GWI30_01915	COG0456	acetyltransferase
GWI30_01960	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GWI30_01980	COG0204	Acyl-transferase
GWI30_01985	COG1842	Phage shock protein A
GWI30_02005	COG2827	Endonuclease containing a URI domain
GWI30_02015	COG1573	uracil-dna glycosylase
GWI30_02025	COG0583	DNA-binding transcription factor activity
GWI30_02030	COG1108	ABC-type Mn2 Zn2 transport systems permease components
GWI30_02035	COG1121	(ABC) transporter
GWI30_02040	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
GWI30_02060	COG0739	heme binding
GWI30_02070	COG3068	Protein conserved in bacteria
GWI30_02090	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
GWI30_02100	COG1546	Belongs to the CinA family
GWI30_02105	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
GWI30_02120	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
GWI30_02125	COG0527	aspartate kinase activity
GWI30_02130	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
GWI30_02165	COG1686	Belongs to the peptidase S11 family
GWI30_02170	COG0586	Pfam SNARE associated Golgi protein
GWI30_02175	COG1253	flavin adenine dinucleotide binding
GWI30_02185	COG2927	DNA polymerase III (CHI subunit)
GWI30_02190	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
GWI30_02195	COG0795	lipopolysaccharide-transporting ATPase activity
GWI30_02200	COG0795	lipopolysaccharide-transporting ATPase activity
GWI30_02220	COG0004	ammonium transporteR
GWI30_02225	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
GWI30_02245	COG0084	hydrolase, TatD family'
GWI30_02250	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
GWI30_02260	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
GWI30_02265	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
GWI30_02270	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
GWI30_02285	COG3064	Membrane
GWI30_02295	COG0560	Phosphoserine phosphatase
GWI30_02310	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
GWI30_02320	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
GWI30_02325	COG0776	regulation of translation
GWI30_02340	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
GWI30_02345	COG0735	belongs to the Fur family
GWI30_02365	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
GWI30_02370	COG0513	Belongs to the DEAD box helicase family
GWI30_02375	COG3022	response to hydroperoxide
GWI30_02390	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
GWI30_02395	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
GWI30_02400	COG0762	integral membrane protein
GWI30_02405	COG1872	DUF167
GWI30_02425	COG3112	Uncharacterised protein family (UPF0231)
GWI30_02430	COG3835	regulator
GWI30_02435	COG2610	gluconate transmembrane transporter activity
GWI30_02440	COG1929	Belongs to the glycerate kinase type-1 family
GWI30_02455	COG0583	DNA-binding transcription factor activity
GWI30_02460	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
GWI30_02475	COG0347	Belongs to the P(II) protein family
GWI30_02480	COG1840	ABC-type Fe3 transport system, periplasmic component
GWI30_02495	COG2837	iron assimilation
GWI30_02500	COG1438	arginine binding
GWI30_02505	COG1126	abc transporter atp-binding protein
GWI30_02510	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GWI30_02515	COG4215	(ABC) transporter
GWI30_02520	COG4160	amino acid transport
GWI30_02525	COG0039	L-malate dehydrogenase activity
GWI30_02530	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
GWI30_02535	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
GWI30_02535	COG1017	nitric oxide dioxygenase activity
GWI30_02545	COG4536	flavin adenine dinucleotide binding
GWI30_02550	COG4137	Cytochrome C assembly protein
GWI30_02555	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
GWI30_02560	COG0228	four-way junction DNA binding
GWI30_02565	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
GWI30_02570	COG0336	Belongs to the RNA methyltransferase TrmD family
GWI30_02575	COG0335	large ribosomal subunit rRNA binding
GWI30_02590	COG1051	belongs to the nudix hydrolase family
GWI30_02600	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
GWI30_02605	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
GWI30_02615	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
GWI30_02625	COG0583	DNA-binding transcription factor activity
GWI30_02630	COG0640	Transcriptional regulator
GWI30_02635	COG0268	Binds directly to 16S ribosomal RNA
GWI30_02640	COG0728	peptidoglycan biosynthetic process
GWI30_02645	COG0196	riboflavin kinase activity
GWI30_02650	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
GWI30_02655	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
GWI30_02660	COG1047	Peptidyl-prolyl cis-trans
GWI30_02665	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
GWI30_02685	COG5433	transposase activity
GWI30_02715	COG4584	PFAM Integrase catalytic
GWI30_02720	COG1484	DNA-dependent DNA replication
GWI30_02730	COG5433	transposase activity
GWI30_02735	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
GWI30_02735	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
GWI30_02750	COG1854	S-ribosylhomocysteine lyase activity
GWI30_02760	COG3706	GGDEF domain
GWI30_02765	COG0557	exoribonuclease II activity
GWI30_02770	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
GWI30_02780	COG2153	protein acetylation
GWI30_02795	COG1914	H( )-stimulated, divalent metal cation uptake system
GWI30_02800	COG0360	Binds together with S18 to 16S ribosomal RNA
GWI30_02805	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
GWI30_02810	COG0359	binds to the 23S rRNA
GWI30_02825	COG3328	transposase activity
GWI30_02840	COG1064	alcohol dehydrogenase
GWI30_02845	COG1238	metal cluster binding
GWI30_02850	COG0612	Peptidase, M16
GWI30_02855	COG2918	glutathione biosynthetic process
GWI30_02860	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
GWI30_02865	COG1027	Aspartate ammonia-lyase
GWI30_02870	COG3030	protein affecting phage T7 exclusion by the F plasmid
GWI30_02875	COG0534	Mate efflux family protein
GWI30_02880	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
GWI30_02885	COG0459	protein refolding
GWI30_02905	COG0564	pseudouridine synthase activity
GWI30_02910	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
GWI30_02950	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
GWI30_02955	COG4208	sulfate ABC transporter
GWI30_02960	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
GWI30_02965	COG0583	DNA-binding transcription factor activity
GWI30_02975	COG3397	chitin binding
GWI30_02980	COG0840	transmembrane signaling receptor activity
GWI30_03005	COG1328	CTP reductase activity
GWI30_03010	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
GWI30_03025	COG1448	Aminotransferase
GWI30_03055	COG1215	transferase activity, transferring glycosyl groups
GWI30_03065	COG0457	Tetratricopeptide repeat
GWI30_03065	COG3118	belongs to the thioredoxin family
GWI30_03090	COG5433	transposase activity
GWI30_03115	COG0513	Belongs to the DEAD box helicase family
GWI30_03135	COG0840	transmembrane signaling receptor activity
GWI30_03145	COG4166	transmembrane transport
GWI30_03160	COG1024	Enoyl-CoA hydratase
GWI30_03175	COG4221	oxidoreductase activity
GWI30_03180	COG0442	prolyl-tRNA aminoacylation
GWI30_03185	COG0632	four-way junction helicase activity
GWI30_03190	COG2255	four-way junction helicase activity
GWI30_03195	COG1271	oxidase subunit
GWI30_03200	COG1294	oxidase, subunit
GWI30_03205	COG4890	Cyd operon protein YbgT
GWI30_03210	COG3790	cyd operon protein YbgE
GWI30_03215	COG0824	Thioesterase
GWI30_03220	COG0811	peptide transport
GWI30_03235	COG0823	Involved in the tonB-independent uptake of proteins
GWI30_03240	COG2885	chlorophyll binding
GWI30_03245	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
GWI30_03320	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
GWI30_03330	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
GWI30_03335	COG1640	4-alpha-glucanotransferase
GWI30_03340	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
GWI30_03365	COG2130	NADP-dependent
GWI30_03370	COG1846	Transcriptional regulator
GWI30_03400	COG0561	phosphatase activity
GWI30_03415	COG0733	neurotransmitter:sodium symporter activity
GWI30_03420	COG0733	neurotransmitter:sodium symporter activity
GWI30_03435	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GWI30_03450	COG1794	racemase activity, acting on amino acids and derivatives
GWI30_03460	COG1022	Amp-dependent synthetase and ligase
GWI30_03470	COG0456	acetyltransferase
GWI30_03485	COG2425	protein containing a von Willebrand factor type A (vWA) domain
GWI30_03490	COG3300	MHYT domain
GWI30_03490	COG5001	Diguanylate cyclase
GWI30_03500	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
GWI30_03510	COG1902	pentaerythritol trinitrate reductase activity
GWI30_03530	COG2957	Belongs to the agmatine deiminase family
GWI30_03535	COG0154	amidase activity
GWI30_03555	COG0513	Belongs to the DEAD box helicase family
GWI30_03560	COG3706	GGDEF domain
GWI30_03570	COG1912	Pfam S-adenosyl-l-methionine hydroxide adenosyltransferase
GWI30_03625	COG4584	PFAM Integrase catalytic
GWI30_03630	COG1484	DNA-dependent DNA replication
GWI30_03645	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
GWI30_03650	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
GWI30_03655	COG1178	ABC-type Fe3 transport system permease component
GWI30_03660	COG4143	(ABC) transporter
GWI30_03675	COG0066	3-isopropylmalate dehydratase activity
GWI30_03680	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
GWI30_03685	COG0473	3-isopropylmalate dehydrogenase activity
GWI30_03690	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
GWI30_03700	COG0671	phosphoesterase, PA-phosphatase related
GWI30_03705	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
GWI30_03715	COG0028	Belongs to the TPP enzyme family
GWI30_03720	COG0440	acetolactate synthase activity
GWI30_03725	COG0280	phosphate acetyltransferase
GWI30_03725	COG0857	belongs to the CobB CobQ family
GWI30_03730	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
GWI30_03740	COG3013	Belongs to the UPF0304 family
GWI30_03745	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
GWI30_03750	COG2716	regulation of RNA biosynthetic process
GWI30_03755	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
GWI30_03760	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
GWI30_03765	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
GWI30_03800	COG0784	Response regulator, receiver
GWI30_03800	COG5002	protein histidine kinase activity
GWI30_03800	COG2198	Histidine kinase
GWI30_03805	COG0232	Belongs to the dGTPase family. Type 2 subfamily
GWI30_03815	COG5433	transposase activity
GWI30_03825	COG3300	MHYT domain
GWI30_03825	COG5001	Diguanylate cyclase
GWI30_03860	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
GWI30_03870	COG0488	(ABC) transporter
GWI30_03875	COG0517	IMP dehydrogenase activity
GWI30_03885	COG3385	transposase activity
GWI30_03895	COG3039	Transposase
GWI30_03900	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
GWI30_03915	COG2755	lipolytic protein G-D-S-L family
GWI30_03920	COG4181	ATPase activity
GWI30_03925	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
GWI30_03930	COG1090	epimerase
GWI30_03935	COG2200	EAL domain
GWI30_03940	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GWI30_03945	COG4935	Belongs to the peptidase S8 family
GWI30_03945	COG2234	aminopeptidase activity
GWI30_03950	COG0220	tRNA (guanine-N7-)-methyltransferase activity
GWI30_03955	COG3171	Protein conserved in bacteria
GWI30_03960	COG2066	Belongs to the glutaminase family
GWI30_03965	COG2897	thiosulfate sulfurtransferase activity
GWI30_03975	COG1132	(ABC) transporter
GWI30_04010	COG0582	viral genome integration into host DNA
GWI30_04020	COG4974	Belongs to the 'phage' integrase family
GWI30_04065	COG5433	transposase activity
GWI30_04080	COG3385	transposase activity
GWI30_04095	COG3335	DDE superfamily endonuclease
GWI30_04125	COG3039	Transposase
GWI30_04135	COG2211	Major facilitator Superfamily
GWI30_04145	COG1609	Transcriptional regulator
GWI30_04155	COG2017	converts alpha-aldose to the beta-anomer
GWI30_04160	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
GWI30_04170	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
GWI30_04180	COG3076	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome
GWI30_04190	COG3300	MHYT domain
GWI30_04190	COG5001	Diguanylate cyclase
GWI30_04205	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
GWI30_04220	COG4628	conserved protein (DUF2132)
GWI30_04225	COG0688	phosphatidylethanolamine metabolic process
GWI30_04235	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
GWI30_04275	COG1278	Cold shock
GWI30_04285	COG0840	transmembrane signaling receptor activity
GWI30_04290	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
GWI30_04295	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
GWI30_04350	COG0848	biopolymer transport protein
GWI30_04355	COG0811	peptide transport
GWI30_04360	COG0811	peptide transport
GWI30_04370	COG4206	TonB-dependent receptor
GWI30_04375	COG5433	transposase activity
GWI30_04385	COG4174	ABC transporter (Permease)
GWI30_04390	COG4239	(ABC) transporter, permease
GWI30_04395	COG0747	negative chemotaxis
GWI30_04400	COG0444	Belongs to the ABC transporter superfamily
GWI30_04405	COG4608	Belongs to the ABC transporter superfamily
GWI30_04415	COG2195	Cleaves the N-terminal amino acid of tripeptides
GWI30_04425	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
GWI30_04445	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
GWI30_04470	COG0243	molybdopterin cofactor binding
GWI30_04485	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
GWI30_04485	COG1116	anion transmembrane transporter activity
GWI30_04490	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
GWI30_04495	COG1116	anion transmembrane transporter activity
GWI30_04500	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
GWI30_04500	COG2146	nitrite reductase [NAD(P)H] activity
GWI30_04505	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
GWI30_04505	COG2146	nitrite reductase [NAD(P)H] activity
GWI30_04510	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GWI30_04515	COG2313	pseudouridylate synthase activity
GWI30_04530	COG3385	transposase activity
GWI30_04535	COG5433	transposase activity
GWI30_04545	COG3385	transposase activity
GWI30_04570	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
GWI30_04575	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
GWI30_04600	COG2986	histidine ammonia-lyase
GWI30_04625	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
GWI30_04635	COG1028	Short-chain dehydrogenase reductase Sdr
GWI30_04640	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
GWI30_04650	COG0521	Mo-molybdopterin cofactor biosynthetic process
GWI30_04665	COG2966	Psort location CytoplasmicMembrane, score
GWI30_04670	COG3610	response to peptide
GWI30_04680	COG4175	Glycine betaine
GWI30_04685	COG4176	ABC-type proline glycine betaine transport system permease component
GWI30_04690	COG2113	Glycine betaine
GWI30_04695	COG0175	sulfate reduction
GWI30_04700	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
GWI30_04705	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
GWI30_04710	COG0384	phenazine biosynthesis protein PhzF
GWI30_04715	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
GWI30_04730	COG5001	Diguanylate cyclase
GWI30_04745	COG0252	asparaginase activity
GWI30_04750	COG3139	Protein of unknown function (DUF1315)
GWI30_04770	COG0616	signal peptide processing
GWI30_04775	COG1902	pentaerythritol trinitrate reductase activity
GWI30_04775	COG0446	pyridine nucleotide-disulphide oxidoreductase
GWI30_04780	COG0778	Nitroreductase
GWI30_04795	COG2264	protein methyltransferase activity
GWI30_04805	COG0583	DNA-binding transcription factor activity
GWI30_04810	COG1263	PTS System
GWI30_04810	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GWI30_04810	COG2190	(PTS) system
GWI30_04815	COG4145	pantothenate transmembrane transporter activity
GWI30_04820	COG3924	membrane
GWI30_04825	COG0439	Biotin carboxylase
GWI30_04830	COG0511	ligase activity, forming carbon-carbon bonds
GWI30_04835	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
GWI30_04840	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
GWI30_04855	COG3381	protein complex oligomerization
GWI30_04865	COG3005	denitrification pathway
GWI30_04870	COG0745	RESPONSE REGULATOR receiver
GWI30_04880	COG1879	ABC-type sugar transport system periplasmic component
GWI30_04885	COG2205	protein histidine kinase activity
GWI30_04885	COG2198	Histidine kinase
GWI30_04885	COG0784	Response regulator, receiver
GWI30_04895	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
GWI30_04910	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
GWI30_04915	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
GWI30_04915	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
GWI30_04930	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
GWI30_04935	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
GWI30_04940	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
GWI30_04945	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
GWI30_04950	COG4172	Belongs to the ABC transporter superfamily
GWI30_04970	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
GWI30_04975	COG0142	geranyltranstransferase activity
GWI30_04980	COG1722	exodeoxyribonuclease VII activity
GWI30_04985	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
GWI30_04990	COG1360	Flagellar Motor Protein
GWI30_05005	COG1534	Rna-binding protein
GWI30_05010	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
GWI30_05020	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
GWI30_05025	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
GWI30_05030	COG0149	triose-phosphate isomerase activity
GWI30_05035	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
GWI30_05050	COG0779	Required for maturation of 30S ribosomal subunits
GWI30_05055	COG0195	Participates in both transcription termination and antitermination
GWI30_05060	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
GWI30_05065	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
GWI30_05070	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
GWI30_05075	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
GWI30_05080	COG1185	polyribonucleotide nucleotidyltransferase activity
GWI30_05085	COG2211	Major facilitator Superfamily
GWI30_05090	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
GWI30_05110	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
GWI30_05130	COG0312	modulator of DNA gyrase
GWI30_05145	COG4974	Belongs to the 'phage' integrase family
GWI30_05155	COG1970	mechanosensitive ion channel activity
GWI30_05180	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
GWI30_05210	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
GWI30_05220	COG0321	lipoyl(octanoyl) transferase activity
GWI30_05225	COG2921	Belongs to the UPF0250 family
GWI30_05230	COG1686	Belongs to the peptidase S11 family
GWI30_05235	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
GWI30_05240	COG2951	lytic endotransglycosylase activity
GWI30_05245	COG0772	Belongs to the SEDS family
GWI30_05250	COG0768	penicillin binding
GWI30_05255	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
GWI30_05260	COG0799	negative regulation of ribosome biogenesis
GWI30_05265	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
GWI30_05280	COG0495	leucyl-tRNA aminoacylation
GWI30_05285	COG2888	peptidyl-tyrosine sulfation
GWI30_05290	COG0815	Transfers the fatty acyl group on membrane lipoproteins
GWI30_05295	COG4535	Mg2 and Co2 transporter CorC
GWI30_05300	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
GWI30_05305	COG1702	phosphate starvation-inducible protein PhoH
GWI30_05310	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
GWI30_05315	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
GWI30_05320	COG1278	Cold shock
GWI30_05325	COG0583	DNA-binding transcription factor activity
GWI30_05335	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
GWI30_05360	COG3706	GGDEF domain
GWI30_05370	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
GWI30_05380	COG3647	Membrane
GWI30_05385	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
GWI30_05395	COG0516	GMP reductase activity
GWI30_05405	COG0642	Histidine kinase
GWI30_05410	COG0745	RESPONSE REGULATOR receiver
GWI30_05420	COG0300	oxidoreductase activity
GWI30_05440	COG4106	trans-aconitate 2-methyltransferase activity
GWI30_05445	COG3214	Protein conserved in bacteria
GWI30_05455	COG3029	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
GWI30_05460	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
GWI30_05465	COG1053	succinate dehydrogenase
GWI30_05475	COG0584	glycerophosphoryl diester phosphodiesterase
GWI30_05480	COG3264	Mechanosensitive ion channel
GWI30_05480	COG1511	domain protein
GWI30_05490	COG0739	heme binding
GWI30_05500	COG3121	Chaperone
GWI30_05505	COG3188	usher protein
GWI30_05510	COG3121	Chaperone
GWI30_05525	COG0583	DNA-binding transcription factor activity
GWI30_05540	COG0583	DNA-binding transcription factor activity
GWI30_05545	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
GWI30_05575	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
GWI30_05580	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
GWI30_05590	COG0338	D12 class N6 adenine-specific DNA methyltransferase
GWI30_05595	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
GWI30_05605	COG0180	Tryptophanyl-tRNA synthetase
GWI30_05620	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
GWI30_05630	COG1012	belongs to the aldehyde dehydrogenase family
GWI30_05640	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
GWI30_05665	COG0490	domain, Protein
GWI30_05665	COG0471	metal ion transport
GWI30_05710	COG0012	GTP binding
GWI30_05715	COG0193	aminoacyl-tRNA hydrolase activity
GWI30_05720	COG0737	Belongs to the 5'-nucleotidase family
GWI30_05725	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
GWI30_05735	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
GWI30_05740	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
GWI30_05745	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
GWI30_05750	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
GWI30_05755	COG2890	protein-(glutamine-N5) methyltransferase activity
GWI30_05765	COG2912	Transglutaminase-like superfamily
GWI30_05775	COG1301	dicarboxylic acid transport
GWI30_05785	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
GWI30_05805	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
GWI30_05810	COG1115	amino acid carrier protein
GWI30_05830	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
GWI30_05840	COG0189	ligase activity
GWI30_05845	COG1385	rRNA (uridine-N3-)-methyltransferase activity
GWI30_05855	COG3091	SprT-like family
GWI30_05865	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
GWI30_05870	COG5433	transposase activity
GWI30_05910	COG3385	transposase activity
GWI30_05930	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
GWI30_05935	COG0739	heme binding
GWI30_05940	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
GWI30_05960	COG3366	ferrous iron transmembrane transporter activity
GWI30_05965	COG0700	Nucleoside recognition
GWI30_05970	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
GWI30_06000	COG0583	DNA-binding transcription factor activity
GWI30_06010	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
GWI30_06020	COG0583	DNA-binding transcription factor activity
GWI30_06025	COG1028	Short-chain dehydrogenase reductase Sdr
GWI30_06030	COG0616	signal peptide processing
GWI30_06035	COG3724	N-succinylarginine dihydrolase activity
GWI30_06055	COG0840	transmembrane signaling receptor activity
GWI30_06065	COG2971	BadF BadG BcrA BcrD
GWI30_06075	COG4608	Belongs to the ABC transporter superfamily
GWI30_06080	COG0444	Belongs to the ABC transporter superfamily
GWI30_06085	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GWI30_06105	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
GWI30_06105	COG1073	alpha beta
GWI30_06105	COG3064	Membrane
GWI30_06115	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
GWI30_06135	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
GWI30_06165	COG1309	transcriptional regulator
GWI30_06205	COG0784	Response regulator, receiver
GWI30_06205	COG0643	Histidine kinase
GWI30_06205	COG2198	Histidine kinase
GWI30_06210	COG2201	protein-glutamate methylesterase activity
GWI30_06215	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
GWI30_06220	COG1360	Flagellar Motor Protein
GWI30_06225	COG1192	Involved in chromosome partitioning
GWI30_06235	COG0835	chemotaxis
GWI30_06250	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
GWI30_06255	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
GWI30_06260	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
GWI30_06265	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
GWI30_06270	COG1138	Cytochrome C-type biogenesis protein
GWI30_06275	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GWI30_06280	COG4235	cytochrome complex assembly
GWI30_06280	COG3088	subunit of a heme lyase
GWI30_06300	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
GWI30_06305	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
GWI30_06305	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
GWI30_06320	COG0259	pyridoxamine-phosphate oxidase activity
GWI30_06335	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
GWI30_06340	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
GWI30_06355	COG0083	homoserine kinase activity
GWI30_06360	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
GWI30_06365	COG4319	ketosteroid isomerase
GWI30_06405	COG2205	protein histidine kinase activity
GWI30_06410	COG0745	RESPONSE REGULATOR receiver
GWI30_06420	COG1091	dTDP-4-dehydrorhamnose reductase activity
GWI30_06440	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
GWI30_06465	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
GWI30_06470	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
GWI30_06525	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
GWI30_06530	COG1763	Mo-molybdopterin cofactor biosynthetic process
GWI30_06535	COG0746	molybdenum cofactor guanylyltransferase activity
GWI30_06540	COG0281	malic enzyme
GWI30_06575	COG5433	transposase activity
GWI30_06585	COG1129	ABC transporter
GWI30_06590	COG1172	Belongs to the binding-protein-dependent transport system permease family
GWI30_06595	COG1472	Belongs to the glycosyl hydrolase 3 family
GWI30_06610	COG3264	Mechanosensitive ion channel
GWI30_06610	COG1196	nuclear chromosome segregation
GWI30_06615	COG0469	pyruvate kinase activity
GWI30_06620	COG2850	peptidyl-arginine hydroxylation
GWI30_06625	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
GWI30_06630	COG2915	High frequency lysogenization protein hflD homolog
GWI30_06635	COG0482	sulfurtransferase activity
GWI30_06655	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GWI30_06665	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GWI30_06665	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
GWI30_06665	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GWI30_06670	COG3385	transposase activity
GWI30_06690	COG5492	domain, Protein
GWI30_06690	COG4932	domain protein
GWI30_06695	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GWI30_06710	COG1482	cell wall glycoprotein biosynthetic process
GWI30_06715	COG2207	Transcriptional regulator
GWI30_06720	COG0538	isocitrate dehydrogenase activity
GWI30_06730	COG3048	D-serine ammonia-lyase activity
GWI30_06735	COG2610	gluconate transmembrane transporter activity
GWI30_06740	COG0583	DNA-binding transcription factor activity
GWI30_06745	COG2916	Histone family protein nucleoid-structuring protein H-NS
GWI30_06750	COG3385	transposase activity
GWI30_06755	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
GWI30_06760	COG2375	cellular response to nickel ion
GWI30_06770	COG0577	efflux transmembrane transporter activity
GWI30_06770	COG1136	(ABC) transporter
GWI30_06775	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GWI30_06785	COG1227	inorganic diphosphatase activity
GWI30_06790	COG0497	DNA recombination
GWI30_06795	COG3706	GGDEF domain
GWI30_06800	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
GWI30_06805	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
GWI30_06810	COG0443	Heat shock 70 kDa protein
GWI30_06815	COG0484	heat shock protein binding
GWI30_06845	COG1285	pathogenesis
GWI30_06875	COG2391	methyltransferase activity
GWI30_06895	COG0095	Lipoate-protein ligase
GWI30_06910	COG0675	Transposase, IS605 OrfB family
GWI30_06930	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
GWI30_06935	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GWI30_06945	COG0708	Exodeoxyribonuclease III
GWI30_06955	COG0745	RESPONSE REGULATOR receiver
GWI30_06970	COG3241	Transfers electrons from cytochrome c551 to cytochrome oxidase
GWI30_06985	COG1846	Transcriptional regulator
GWI30_07000	COG0675	Transposase, IS605 OrfB family
GWI30_07015	COG0583	DNA-binding transcription factor activity
GWI30_07025	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
GWI30_07030	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
GWI30_07035	COG1845	cytochrome c oxidase, subunit III
GWI30_07040	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
GWI30_07045	COG0109	protoheme IX farnesyltransferase activity
GWI30_07050	COG2814	Major facilitator Superfamily
GWI30_07055	COG5507	3-demethylubiquinone-9 3-methyltransferase
GWI30_07090	COG3550	peptidyl-serine autophosphorylation
GWI30_07095	COG1396	sequence-specific DNA binding
GWI30_07135	COG0159	tryptophan synthase activity
GWI30_07140	COG0133	tryptophan synthase activity
GWI30_07145	COG0134	indole-3-glycerol-phosphate synthase activity
GWI30_07145	COG0135	phosphoribosylanthranilate isomerase activity
GWI30_07150	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
GWI30_07155	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
GWI30_07155	COG0512	Glutamine amidotransferase of anthranilate synthase
GWI30_07160	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
GWI30_07170	COG0009	L-threonylcarbamoyladenylate synthase
GWI30_07180	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
GWI30_07190	COG1946	Acyl-CoA thioesterase
GWI30_07205	COG1309	transcriptional regulator
GWI30_07210	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GWI30_07215	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
GWI30_07245	COG4584	PFAM Integrase catalytic
GWI30_07250	COG1484	DNA-dependent DNA replication
GWI30_07270	COG3657	addiction module killer protein
GWI30_07310	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
GWI30_07320	COG1960	acyl-CoA dehydrogenase activity
GWI30_07325	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
GWI30_07335	COG0469	pyruvate kinase activity
GWI30_07340	COG1737	Transcriptional regulator
GWI30_07360	COG0745	RESPONSE REGULATOR receiver
GWI30_07380	COG3039	Transposase
GWI30_07410	COG5433	transposase activity
GWI30_07435	COG5433	transposase activity
GWI30_07440	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
GWI30_07465	COG1216	Glycosyl transferase, family 2
GWI30_07480	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
GWI30_07530	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
GWI30_07545	COG3132	Protein of unknown function, DUF480
GWI30_07585	COG1278	Cold shock
GWI30_07615	COG0697	spore germination
GWI30_07635	COG0675	Transposase, IS605 OrfB family
GWI30_07645	COG1187	pseudouridine synthase activity
GWI30_07660	COG4166	transmembrane transport
GWI30_07665	COG0622	Phosphoesterase
GWI30_07685	COG0835	chemotaxis
GWI30_07685	COG0784	Response regulator, receiver
GWI30_07690	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
GWI30_07695	COG1815	bacterial-type flagellum-dependent cell motility
GWI30_07710	COG1749	Flagellar hook protein flgE
GWI30_07725	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
GWI30_07730	COG1706	bacterial-type flagellum-dependent cell motility
GWI30_07735	COG3951	Flagellar rod assembly protein muramidase FlgJ
GWI30_07735	COG1705	Flagellar rod assembly protein muramidase FlgJ
GWI30_07780	COG0675	Transposase, IS605 OrfB family
GWI30_07795	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
GWI30_07800	COG2716	regulation of RNA biosynthetic process
GWI30_07815	COG3852	Histidine kinase
GWI30_07830	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
GWI30_07835	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
GWI30_07840	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
GWI30_07865	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
GWI30_07880	COG0573	inorganic phosphate transmembrane transporter activity
GWI30_07885	COG0581	inorganic phosphate transmembrane transporter activity
GWI30_07900	COG1253	flavin adenine dinucleotide binding
GWI30_07915	COG0531	amino acid
GWI30_07920	COG3385	transposase activity
GWI30_07930	COG1126	abc transporter atp-binding protein
GWI30_07935	COG0765	amino acid transport
GWI30_07940	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GWI30_07955	COG0675	Transposase, IS605 OrfB family
GWI30_07965	COG2271	Major facilitator Superfamily
GWI30_07975	COG2197	response regulator
GWI30_07980	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
GWI30_08005	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
GWI30_08010	COG0477	Major facilitator Superfamily
GWI30_08015	COG0123	including yeast histone deacetylase and acetoin utilization protein
GWI30_08025	COG1199	ATP-dependent helicase activity
GWI30_08040	COG1448	Aminotransferase
GWI30_08050	COG0433	COG0433 Predicted ATPase
GWI30_08065	COG2333	competence protein COMEC
GWI30_08065	COG0658	competence protein
GWI30_08070	COG1132	(ABC) transporter
GWI30_08075	COG1663	tetraacyldisaccharide 4'-kinase activity
GWI30_08080	COG2835	tetraacyldisaccharide 4'-kinase activity
GWI30_08085	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
GWI30_08090	COG2197	response regulator
GWI30_08095	COG0322	excinuclease ABC activity
GWI30_08135	COG3385	transposase activity
GWI30_08160	COG5433	transposase activity
GWI30_08190	COG0625	glutathione transferase activity
GWI30_08195	COG2261	transglycosylase associated protein
GWI30_08200	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
GWI30_08210	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
GWI30_08230	COG5433	transposase activity
GWI30_08245	COG3385	transposase activity
GWI30_08255	COG5433	transposase activity
GWI30_08280	COG2199	diguanylate cyclase activity
GWI30_08280	COG2203	Gaf domain
GWI30_08315	COG2119	membrane
GWI30_08365	COG4138	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system
GWI30_08370	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
GWI30_08375	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
GWI30_08380	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
GWI30_08385	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
GWI30_08390	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
GWI30_08400	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
GWI30_08405	COG0505	Belongs to the CarA family
GWI30_08410	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
GWI30_08415	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
GWI30_08450	COG0513	Belongs to the DEAD box helicase family
GWI30_08460	COG4104	PAAR repeat-containing protein
GWI30_08475	COG0789	Transcriptional regulator
GWI30_08485	COG0493	'glutamate synthase
GWI30_08490	COG0069	glutamate synthase activity
GWI30_08490	COG0070	glutamate synthase
GWI30_08490	COG0067	glutamate synthase
GWI30_08495	COG1242	4 iron, 4 sulfur cluster binding
GWI30_08500	COG3039	Transposase
GWI30_08535	COG1113	amino acid transport
GWI30_08545	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
GWI30_08550	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
GWI30_08550	COG0574	Belongs to the PEP-utilizing enzyme family
GWI30_08555	COG1119	ATPase activity
GWI30_08570	COG1464	Belongs to the NlpA lipoprotein family
GWI30_08575	COG0671	phosphoesterase, PA-phosphatase related
GWI30_08580	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
GWI30_08585	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
GWI30_08595	COG0101	tRNA pseudouridine synthase activity
GWI30_08600	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
GWI30_08605	COG0285	dihydrofolate synthase activity
GWI30_08610	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
GWI30_08615	COG2920	part of a sulfur-relay system
GWI30_08620	COG1289	transmembrane transporter activity
GWI30_08625	COG0670	Belongs to the BI1 family
GWI30_08650	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
GWI30_08660	COG5433	transposase activity
GWI30_08670	COG2175	clavaminate synthase activity
GWI30_08675	COG3246	L-lysine catabolic process to acetate
GWI30_08680	COG2814	Major facilitator Superfamily
GWI30_08690	COG2855	membrane
GWI30_08735	COG0318	PFAM AMP-dependent synthetase and ligase
GWI30_08740	COG0840	transmembrane signaling receptor activity
GWI30_08745	COG3706	GGDEF domain
GWI30_08750	COG0564	pseudouridine synthase activity
GWI30_08765	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
GWI30_08775	COG0625	glutathione transferase activity
GWI30_08795	COG0367	asparagine synthase
GWI30_08805	COG0647	UMP catabolic process
GWI30_08855	COG1253	flavin adenine dinucleotide binding
GWI30_08865	COG0277	FAD linked oxidase domain protein
GWI30_08865	COG0247	lactate metabolic process
GWI30_08875	COG2050	protein possibly involved in aromatic compounds catabolism
GWI30_08880	COG0513	Belongs to the DEAD box helicase family
GWI30_08885	COG0583	DNA-binding transcription factor activity
GWI30_08890	COG2814	Major facilitator Superfamily
GWI30_08895	COG2056	Na+-H+ antiporter family
GWI30_08900	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
GWI30_08915	COG0483	inositol monophosphate 1-phosphatase activity
GWI30_08930	COG0625	glutathione transferase activity
GWI30_08940	COG0601	transmembrane transport
GWI30_08945	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GWI30_08950	COG1136	(ABC) transporter
GWI30_08950	COG0577	efflux transmembrane transporter activity
GWI30_08955	COG2814	Major facilitator Superfamily
GWI30_08975	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
GWI30_08980	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
GWI30_08985	COG0404	The glycine cleavage system catalyzes the degradation of glycine
GWI30_08990	COG0509	glycine decarboxylation via glycine cleavage system
GWI30_08995	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
GWI30_08995	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
GWI30_09000	COG3039	Transposase
GWI30_09030	COG3634	alkyl hydroperoxide reductase activity
GWI30_09040	COG0517	IMP dehydrogenase activity
GWI30_09045	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
GWI30_09050	COG0343	queuine tRNA-ribosyltransferase activity
GWI30_09055	COG1862	Preprotein translocase
GWI30_09060	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
GWI30_09065	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
GWI30_09080	COG0826	peptidase U32
GWI30_09085	COG0826	peptidase U32
GWI30_09090	COG3154	lipid carrier protein
GWI30_09110	COG1104	cysteine desulfurase activity
GWI30_09115	COG0822	iron-sulfur transferase activity
GWI30_09125	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
GWI30_09130	COG0443	Heat shock 70 kDa protein
GWI30_09135	COG0633	Ferredoxin
GWI30_09145	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
GWI30_09150	COG0105	UTP biosynthetic process
GWI30_09155	COG0820	rRNA (adenine-C2-)-methyltransferase activity
GWI30_09175	COG0124	histidyl-tRNA synthetase
GWI30_09180	COG2976	Protein conserved in bacteria
GWI30_09185	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
GWI30_09190	COG1160	GTP binding
GWI30_09200	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
GWI30_09205	COG0047	phosphoribosylformylglycinamidine synthase activity
GWI30_09205	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
GWI30_09215	COG1007	ATP synthesis coupled electron transport
GWI30_09220	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
GWI30_09230	COG0713	ATP synthesis coupled electron transport
GWI30_09235	COG0839	Belongs to the complex I subunit 6 family
GWI30_09240	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
GWI30_09245	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
GWI30_09250	COG1034	ATP synthesis coupled electron transport
GWI30_09265	COG0649	NAD binding
GWI30_09265	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
GWI30_09270	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
GWI30_09275	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
GWI30_09280	COG1360	Flagellar Motor Protein
GWI30_09285	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
GWI30_09305	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
GWI30_09315	COG3770	Murein endopeptidase that cleaves the D-alanyl-meso-2,6- diamino-pimelyl amide bond that connects peptidoglycan strands. Likely plays a role in the removal of murein from the sacculus
GWI30_09325	COG0724	RNA recognition motif
GWI30_09330	COG4989	oxidoreductase activity
GWI30_09355	COG3437	response regulator, receiver
GWI30_09360	COG0583	DNA-binding transcription factor activity
GWI30_09370	COG5001	Diguanylate cyclase
GWI30_09370	COG3300	MHYT domain
GWI30_09375	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
GWI30_09395	COG2814	Major facilitator Superfamily
GWI30_09405	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
GWI30_09410	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
GWI30_09415	COG0539	negative regulation of cytoplasmic translation
GWI30_09420	COG0776	regulation of translation
GWI30_09430	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
GWI30_09450	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
GWI30_09455	COG0602	queuosine metabolic process
GWI30_09460	COG3530	Putative quorum-sensing-regulated virulence factor
GWI30_09465	COG2096	Adenosyltransferase
GWI30_09470	COG2916	Histone family protein nucleoid-structuring protein H-NS
GWI30_09475	COG1757	Na H antiporter
GWI30_09515	COG3550	peptidyl-serine autophosphorylation
GWI30_09595	COG4683	PFAM Phage derived protein Gp49-like (DUF891)
GWI30_09605	COG3039	Transposase
GWI30_09615	COG2226	methyltransferase
GWI30_09635	COG3550	peptidyl-serine autophosphorylation
GWI30_09755	COG5433	transposase activity
GWI30_09760	COG5433	transposase activity
GWI30_09765	COG3039	Transposase
GWI30_09790	COG0629	single-stranded DNA binding
GWI30_09795	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
GWI30_09800	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
GWI30_09820	COG1484	DNA-dependent DNA replication
GWI30_09830	COG5433	transposase activity
GWI30_09910	COG1104	cysteine desulfurase activity
GWI30_09920	COG5433	transposase activity
GWI30_09935	COG3385	transposase activity
GWI30_09975	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
GWI30_09980	COG0626	cystathionine gamma-synthase activity
GWI30_09990	COG2910	NAD(P)H-binding
GWI30_09995	COG0583	DNA-binding transcription factor activity
GWI30_10005	COG3708	Transcriptional regulator
GWI30_10005	COG2207	Transcriptional regulator
GWI30_10010	COG4774	siderophore transport
GWI30_10030	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
GWI30_10035	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
GWI30_10035	COG3620	sequence-specific DNA binding
GWI30_10035	COG0617	tRNA 3'-terminal CCA addition
GWI30_10050	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
GWI30_10055	COG3046	protein related to deoxyribodipyrimidine photolyase
GWI30_10070	COG3088	subunit of a heme lyase
GWI30_10070	COG4235	cytochrome complex assembly
GWI30_10075	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GWI30_10080	COG1138	Cytochrome C-type biogenesis protein
GWI30_10085	COG3301	Polysulphide reductase, NrfD
GWI30_10090	COG0437	4 iron, 4 sulfur cluster binding
GWI30_10095	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
GWI30_10110	COG0247	lactate metabolic process
GWI30_10115	COG3075	Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses fumarate or nitrate as electron acceptor
GWI30_10120	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
GWI30_10125	COG3012	SEC-C Motif Domain Protein
GWI30_10135	COG1940	carbohydrate kinase activity
GWI30_10135	COG1846	Transcriptional regulator
GWI30_10140	COG3290	protein histidine kinase activity
GWI30_10145	COG4565	transcriptional regulatory protein
GWI30_10175	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
GWI30_10180	COG2985	domain, Protein
GWI30_10180	COG0569	domain protein
GWI30_10195	COG0556	nucleotide-excision repair
GWI30_10205	COG0586	Pfam SNARE associated Golgi protein
GWI30_10215	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
GWI30_10220	COG3067	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
GWI30_10230	COG2719	SpoVR family
GWI30_10235	COG2718	Belongs to the UPF0229 family
GWI30_10240	COG2766	serine protein kinase
GWI30_10245	COG0514	ATP-dependent DNA helicase (RecQ)
GWI30_10250	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
GWI30_10255	COG0814	amino acid
GWI30_10260	COG5433	transposase activity
GWI30_10290	COG5433	transposase activity
GWI30_10295	COG0058	SHG alpha-glucan phosphorylase activity
GWI30_10310	COG0471	metal ion transport
GWI30_10315	COG3118	belongs to the thioredoxin family
GWI30_10325	COG1132	(ABC) transporter
GWI30_10330	COG1132	(ABC) transporter
GWI30_10350	COG2501	S4 domain
GWI30_10380	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
GWI30_10385	COG2329	Antibiotic biosynthesis monooxygenase
GWI30_10390	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
GWI30_10395	COG0673	inositol 2-dehydrogenase activity
GWI30_10400	COG0583	DNA-binding transcription factor activity
GWI30_10410	COG1560	Kdo2-lipid A biosynthetic process
GWI30_10415	COG1560	Kdo2-lipid A biosynthetic process
GWI30_10435	COG0417	DNA replication proofreading
GWI30_10475	COG0307	riboflavin synthase, alpha
GWI30_10485	COG0675	Transposase, IS605 OrfB family
GWI30_10495	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
GWI30_10500	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
GWI30_10505	COG0697	spore germination
GWI30_10510	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
GWI30_10545	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
GWI30_10550	COG3099	Belongs to the UPF0263 family
GWI30_10555	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
GWI30_10560	COG2894	cell division
GWI30_10565	COG0850	regulation of cytokinetic process
GWI30_10570	COG3100	YcgL domain-containing protein
GWI30_10575	COG2951	lytic endotransglycosylase activity
GWI30_10585	COG1760	l-serine dehydratase
GWI30_10590	COG1760	l-serine dehydratase
GWI30_10595	COG3123	guanosine phosphorylase activity
GWI30_10615	COG2067	long-chain fatty acid transport protein
GWI30_10620	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
GWI30_10625	COG2067	long-chain fatty acid transport protein
GWI30_10635	COG2067	long-chain fatty acid transport protein
GWI30_10655	COG2304	oxidoreductase activity
GWI30_10680	COG0714	Associated with various cellular activities
GWI30_10685	COG0183	Belongs to the thiolase family
GWI30_10690	COG1250	3-hydroxyacyl-CoA dehydrogenase
GWI30_10690	COG1024	Enoyl-CoA hydratase
GWI30_10700	COG4681	YaeQ
GWI30_10735	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GWI30_10750	COG3134	Outer membrane lipoprotein
GWI30_10755	COG0318	PFAM AMP-dependent synthetase and ligase
GWI30_10760	COG2378	regulation of single-species biofilm formation
GWI30_10770	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
GWI30_10770	COG0140	phosphoribosyl-ATP diphosphatase activity
GWI30_10775	COG0107	imidazoleglycerol-phosphate synthase activity
GWI30_10780	COG0784	Response regulator, receiver
GWI30_10780	COG2205	protein histidine kinase activity
GWI30_10780	COG2198	Histidine kinase
GWI30_10790	COG3437	response regulator, receiver
GWI30_10795	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
GWI30_10800	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
GWI30_10805	COG0131	Imidazoleglycerol-phosphate dehydratase
GWI30_10805	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
GWI30_10810	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
GWI30_10815	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
GWI30_10820	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
GWI30_10830	COG1199	ATP-dependent helicase activity
GWI30_10835	COG1214	PFAM Peptidase M22, glycoprotease
GWI30_10845	COG0596	Alpha beta hydrolase
GWI30_10850	COG0318	PFAM AMP-dependent synthetase and ligase
GWI30_10855	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
GWI30_10865	COG5433	transposase activity
GWI30_10920	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
GWI30_10925	COG2832	Protein of unknown function (DUF454)
GWI30_10930	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
GWI30_10940	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
GWI30_10945	COG1335	isochorismatase
GWI30_10965	COG3385	transposase activity
GWI30_10985	COG0617	tRNA 3'-terminal CCA addition
GWI30_10985	COG0517	IMP dehydrogenase activity
GWI30_10985	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
GWI30_10990	COG1643	Atp-dependent helicase
GWI30_11000	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
GWI30_11010	COG3437	response regulator, receiver
GWI30_11015	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GWI30_11020	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
GWI30_11025	COG0709	Synthesizes selenophosphate from selenide and ATP
GWI30_11035	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
GWI30_11040	COG0840	transmembrane signaling receptor activity
GWI30_11045	COG1254	Belongs to the acylphosphatase family
GWI30_11055	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GWI30_11055	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GWI30_11060	COG0489	protein tyrosine kinase activity
GWI30_11065	COG0572	uridine kinase
GWI30_11070	COG0717	Belongs to the dCTP deaminase family
GWI30_11075	COG0306	phosphate transporter
GWI30_11080	COG4584	PFAM Integrase catalytic
GWI30_11090	COG1530	ribonuclease E activity
GWI30_11100	COG0546	phosphoglycolate phosphatase activity
GWI30_11105	COG0424	maF-like protein
GWI30_11115	COG1399	metal-binding, possibly nucleic acid-binding protein
GWI30_11120	COG0333	Belongs to the bacterial ribosomal protein bL32 family
GWI30_11125	COG0416	fatty acid biosynthetic process
GWI30_11130	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
GWI30_11140	COG1028	Short-chain dehydrogenase reductase Sdr
GWI30_11145	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
GWI30_11155	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
GWI30_11160	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
GWI30_11165	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
GWI30_11170	COG0470	DNA polymerase III
GWI30_11175	COG0084	hydrolase, TatD family'
GWI30_11190	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
GWI30_11190	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
GWI30_11195	COG3008	intermembrane lipid transfer
GWI30_11200	COG2995	paraquat-inducible protein a
GWI30_11210	COG3141	response to X-ray
GWI30_11220	COG1067	ATP-dependent peptidase activity
GWI30_11225	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
GWI30_11250	COG0116	Belongs to the methyltransferase superfamily
GWI30_11250	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
GWI30_11260	COG3385	transposase activity
GWI30_11270	COG0167	dihydroorotate dehydrogenase activity
GWI30_11275	COG2902	Dehydrogenase
GWI30_11285	COG0308	aminopeptidase N
GWI30_11295	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
GWI30_11300	COG1956	GAF domain-containing protein
GWI30_11310	COG3278	Belongs to the heme-copper respiratory oxidase family
GWI30_11325	COG2010	Cytochrome c
GWI30_11350	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
GWI30_11355	COG0589	response to stress
GWI30_11360	COG0037	tRNA processing
GWI30_11375	COG0625	glutathione transferase activity
GWI30_11380	COG1869	D-ribose catabolic process
GWI30_11385	COG1129	ABC transporter
GWI30_11390	COG1172	Belongs to the binding-protein-dependent transport system permease family
GWI30_11395	COG1879	ABC-type sugar transport system periplasmic component
GWI30_11400	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GWI30_11405	COG1609	Transcriptional regulator
GWI30_11410	COG3300	MHYT domain
GWI30_11410	COG5001	Diguanylate cyclase
GWI30_11435	COG0784	Response regulator, receiver
GWI30_11435	COG2205	protein histidine kinase activity
GWI30_11440	COG0776	regulation of translation
GWI30_11445	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GWI30_11445	COG0072	phenylalanine-tRNA ligase activity
GWI30_11450	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
GWI30_11455	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
GWI30_11460	COG0291	Belongs to the bacterial ribosomal protein bL35 family
GWI30_11465	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
GWI30_11470	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
GWI30_11495	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
GWI30_11505	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
GWI30_11515	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
GWI30_11520	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
GWI30_11525	COG3313	Fe-S protein
GWI30_11530	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GWI30_11530	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GWI30_11530	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
GWI30_11535	COG1105	Belongs to the carbohydrate kinase PfkB family
GWI30_11540	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
GWI30_11540	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
GWI30_11545	COG1609	Transcriptional regulator
GWI30_11550	COG0814	amino acid
GWI30_11555	COG3788	relative of glutathione S-transferase, MAPEG superfamily
GWI30_11560	COG0513	Belongs to the DEAD box helicase family
GWI30_11575	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
GWI30_11580	COG2890	protein-(glutamine-N5) methyltransferase activity
GWI30_11585	COG2840	Smr protein MutS2
GWI30_11595	COG0406	alpha-ribazole phosphatase activity
GWI30_11625	COG2824	Alkylphosphonate utilization operon protein PhnA
GWI30_11690	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
GWI30_11700	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
GWI30_11705	COG1434	Gram-negative-bacterium-type cell wall biogenesis
GWI30_11715	COG0205	6-phosphofructokinase activity
GWI30_11720	COG1473	amidohydrolase
GWI30_11725	COG1011	Hydrolase
GWI30_11730	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
GWI30_11780	COG3593	DNA synthesis involved in DNA repair
GWI30_11795	COG0583	DNA-binding transcription factor activity
GWI30_11800	COG0730	response to heat
GWI30_11815	COG1181	Belongs to the D-alanine--D-alanine ligase family
GWI30_11825	COG0386	Belongs to the glutathione peroxidase family
GWI30_11830	COG0513	Belongs to the DEAD box helicase family
GWI30_11835	COG0456	acetyltransferase
GWI30_11865	COG3706	GGDEF domain
GWI30_11880	COG0583	DNA-binding transcription factor activity
GWI30_11885	COG1028	Short-chain dehydrogenase reductase Sdr
GWI30_11890	COG2723	6-phospho-beta-galactosidase activity
GWI30_11895	COG0583	DNA-binding transcription factor activity
GWI30_11900	COG3706	GGDEF domain
GWI30_11910	COG0243	molybdopterin cofactor binding
GWI30_11915	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
GWI30_11920	COG3039	Transposase
GWI30_11945	COG2003	Belongs to the UPF0758 family
GWI30_11970	COG3385	transposase activity
GWI30_11980	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
GWI30_12000	COG0730	response to heat
GWI30_12010	COG1028	Short-chain dehydrogenase reductase Sdr
GWI30_12020	COG1024	Enoyl-CoA hydratase
GWI30_12025	COG1024	Enoyl-CoA hydratase
GWI30_12030	COG1960	acyl-CoA dehydrogenase activity
GWI30_12040	COG1960	acyl-CoA dehydrogenase activity
GWI30_12045	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
GWI30_12050	COG1024	Enoyl-CoA hydratase
GWI30_12075	COG1584	GPR1 FUN34 yaaH family protein
GWI30_12090	COG1115	amino acid carrier protein
GWI30_12095	COG1024	Enoyl-CoA hydratase
GWI30_12105	COG2176	DNA-directed DNA polymerase activity
GWI30_12110	COG3162	membrane
GWI30_12115	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GWI30_12120	COG0488	(ABC) transporter
GWI30_12125	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
GWI30_12130	COG0776	regulation of translation
GWI30_12135	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
GWI30_12140	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
GWI30_12145	COG0740	serine-type endopeptidase activity
GWI30_12150	COG0544	peptidyl-prolyl cis-trans isomerase activity
GWI30_12170	COG4591	ABC-type transport system involved in lipoprotein release permease component
GWI30_12175	COG1136	(ABC) transporter
GWI30_12180	COG4591	ABC-type transport system involved in lipoprotein release permease component
GWI30_12190	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
GWI30_12195	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
GWI30_12200	COG4166	transmembrane transport
GWI30_12205	COG0697	spore germination
GWI30_12215	COG2062	phosphohistidine phosphatase, SixA
GWI30_12265	COG0519	Catalyzes the synthesis of GMP from XMP
GWI30_12265	COG0518	GMP synthase (glutamine-hydrolyzing) activity
GWI30_12270	COG0516	GMP reductase activity
GWI30_12270	COG0517	IMP dehydrogenase activity
GWI30_12280	COG0366	Alpha amylase catalytic
GWI30_12280	COG1874	Beta-galactosidase
GWI30_12290	COG1570	exodeoxyribonuclease VII activity
GWI30_12300	COG2885	chlorophyll binding
GWI30_12305	COG2199	diguanylate cyclase activity
GWI30_12320	COG2154	pterin-4-alpha-carbinolamine dehydratase
GWI30_12330	COG3768	UPF0283 membrane protein
GWI30_12335	COG3106	COG3106 Predicted ATPase
GWI30_12350	COG1842	Phage shock protein A
GWI30_12355	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
GWI30_12365	COG4168	peptide transport system, permease
GWI30_12370	COG4171	peptide transport system, permease
GWI30_12380	COG4172	Belongs to the ABC transporter superfamily
GWI30_12390	COG1609	Transcriptional regulator
GWI30_12400	COG2723	6-phospho-beta-galactosidase activity
GWI30_12405	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
GWI30_12410	COG1286	toxin biosynthetic process
GWI30_12415	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
GWI30_12420	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
GWI30_12425	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
GWI30_12430	COG1674	ftsk spoiiie
GWI30_12430	COG0531	amino acid
GWI30_12440	COG0686	Belongs to the AlaDH PNT family
GWI30_12445	COG0492	ferredoxin-NADP+ reductase activity
GWI30_12450	COG3706	GGDEF domain
GWI30_12455	COG3134	Outer membrane lipoprotein
GWI30_12460	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
GWI30_12465	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
GWI30_12470	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
GWI30_12475	COG0542	response to heat
GWI30_12480	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
GWI30_12485	COG1278	Cold shock
GWI30_12490	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
GWI30_12510	COG1944	ATP diphosphatase activity
GWI30_12515	COG2116	formate transmembrane transporter activity
GWI30_12520	COG1882	Formate acetyltransferase
GWI30_12525	COG2983	Belongs to the UPF0260 family
GWI30_12535	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
GWI30_12540	COG0045	succinate-CoA ligase (ADP-forming) activity
GWI30_12545	COG0508	dehydrogenase complex catalyzes the overall conversion of
GWI30_12550	COG0567	Dehydrogenase, E1 component
GWI30_12560	COG1053	succinate dehydrogenase
GWI30_12565	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
GWI30_12590	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
GWI30_12595	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
GWI30_12595	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
GWI30_12605	COG3069	C4-dicarboxylate transmembrane transporter activity
GWI30_12620	COG1451	nucleotide metabolic process
GWI30_12635	COG0254	rRNA binding
GWI30_12640	COG0257	Belongs to the bacterial ribosomal protein bL36 family
GWI30_12650	COG1172	Belongs to the binding-protein-dependent transport system permease family
GWI30_12655	COG1129	ABC transporter
GWI30_12660	COG1879	ABC-type sugar transport system periplasmic component
GWI30_12665	COG1069	ribulokinase activity
GWI30_12675	COG2160	L-arabinose isomerase activity
GWI30_12680	COG0583	DNA-binding transcription factor activity
GWI30_12685	COG0436	Aminotransferase
GWI30_12690	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
GWI30_12720	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
GWI30_12725	COG2925	Exonuclease
GWI30_12735	COG3345	alpha-galactosidase
GWI30_12740	COG1380	Effector of murein hydrolase LrgA
GWI30_12745	COG1346	cytolysis
GWI30_12750	COG0295	cytidine deaminase activity
GWI30_12755	COG1022	Amp-dependent synthetase and ligase
GWI30_12770	COG0861	Integral membrane protein TerC family
GWI30_12775	COG3385	transposase activity
GWI30_12780	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
GWI30_12785	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
GWI30_12790	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
GWI30_12810	COG0644	oxidoreductase
GWI30_12810	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
GWI30_12835	COG4771	TonB-dependent receptor
GWI30_12840	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GWI30_12845	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GWI30_12850	COG1120	ATPase activity
GWI30_12860	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
GWI30_12865	COG3321	synthase
GWI30_12865	COG1028	Short-chain dehydrogenase reductase Sdr
GWI30_12865	COG0300	oxidoreductase activity
GWI30_12865	COG0318	PFAM AMP-dependent synthetase and ligase
GWI30_12865	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GWI30_12875	COG1028	Short-chain dehydrogenase reductase Sdr
GWI30_12880	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GWI30_12885	COG1535	isochorismatase
GWI30_12885	COG3433	isochorismatase activity
GWI30_12890	COG1021	2,3-dihydroxybenzoate-AMP ligase
GWI30_12910	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
GWI30_12915	COG3300	MHYT domain
GWI30_12915	COG5001	Diguanylate cyclase
GWI30_12930	COG0840	transmembrane signaling receptor activity
GWI30_12935	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GWI30_12940	COG3788	relative of glutathione S-transferase, MAPEG superfamily
GWI30_12945	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
GWI30_12950	COG0563	adenylate kinase activity
GWI30_12955	COG0326	Molecular chaperone. Has ATPase activity
GWI30_12960	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
GWI30_12965	COG3039	Transposase
GWI30_12980	COG0659	secondary active sulfate transmembrane transporter activity
GWI30_12985	COG5433	transposase activity
GWI30_13000	COG2308	Evidence 4 Homologs of previously reported genes of
GWI30_13035	COG0672	)-iron permease
GWI30_13060	COG2814	Major facilitator Superfamily
GWI30_13080	COG1136	(ABC) transporter
GWI30_13095	COG3039	Transposase
GWI30_13110	COG1139	Iron-sulfur cluster binding protein
GWI30_13115	COG0247	lactate metabolic process
GWI30_13120	COG1620	l-lactate permease
GWI30_13125	COG0583	DNA-binding transcription factor activity
GWI30_13135	COG2315	Protein conserved in bacteria
GWI30_13150	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
GWI30_13155	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
GWI30_13155	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
GWI30_13165	COG0527	aspartate kinase activity
GWI30_13175	COG1368	sulfuric ester hydrolase activity
GWI30_13195	COG0393	Putative heavy-metal-binding
GWI30_13205	COG1252	NADH dehydrogenase
GWI30_13210	COG3150	esterase
GWI30_13225	COG2354	Protein conserved in bacteria
GWI30_13235	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
GWI30_13240	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
GWI30_13245	COG0675	Transposase, IS605 OrfB family
GWI30_13295	COG0537	adenosine 5'-monophosphoramidase activity
GWI30_13310	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
GWI30_13325	COG1301	dicarboxylic acid transport
GWI30_13335	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
GWI30_13340	COG0861	Integral membrane protein TerC family
GWI30_13350	COG0444	Belongs to the ABC transporter superfamily
GWI30_13355	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GWI30_13360	COG0601	transmembrane transport
GWI30_13370	COG2095	MarC family integral membrane protein
GWI30_13375	COG1454	alcohol dehydrogenase
GWI30_13375	COG1012	belongs to the aldehyde dehydrogenase family
GWI30_13385	COG3275	phosphorelay sensor kinase activity
GWI30_13390	COG3279	Response regulator of the LytR AlgR family
GWI30_13395	COG1966	Carbon starvation protein
GWI30_13400	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
GWI30_13400	COG3264	Mechanosensitive ion channel
GWI30_13410	COG0675	Transposase, IS605 OrfB family
GWI30_13425	COG1566	PFAM secretion protein HlyD family protein
GWI30_13430	COG1061	Type III restriction enzyme res subunit
GWI30_13435	COG2027	D-alanyl-D-alanine carboxypeptidase
GWI30_13440	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
GWI30_13450	COG0436	Aminotransferase
GWI30_13460	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
GWI30_13480	COG0697	spore germination
GWI30_13485	COG4657	Part of a membrane complex involved in electron transport
GWI30_13490	COG2878	Part of a membrane complex involved in electron transport
GWI30_13500	COG4658	electron transport chain
GWI30_13505	COG4659	FMN binding
GWI30_13510	COG4660	Part of a membrane complex involved in electron transport
GWI30_13515	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
GWI30_13520	COG0346	lactoylglutathione lyase activity
GWI30_13535	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
GWI30_13545	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
GWI30_13570	COG5433	transposase activity
GWI30_13600	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
GWI30_13615	COG0301	tRNA thio-modification
GWI30_13615	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
GWI30_13625	COG4953	penicillin-binding protein 1C
GWI30_13630	COG2373	Large extracellular alpha-helical protein
GWI30_13645	COG0446	pyridine nucleotide-disulphide oxidoreductase
GWI30_13655	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
GWI30_13675	COG3385	transposase activity
GWI30_13680	COG5433	transposase activity
GWI30_13740	COG1216	Glycosyl transferase, family 2
GWI30_13740	COG0438	transferase activity, transferring glycosyl groups
GWI30_13750	COG1210	Utp--glucose-1-phosphate uridylyltransferase
GWI30_13760	COG1091	dTDP-4-dehydrorhamnose reductase activity
GWI30_13770	COG5433	transposase activity
GWI30_13795	COG4160	amino acid transport
GWI30_13805	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GWI30_13815	COG2431	L-lysine efflux transmembrane transporter activity
GWI30_13820	COG3385	transposase activity
GWI30_13825	COG0675	Transposase, IS605 OrfB family
GWI30_13840	COG1393	Belongs to the ArsC family
GWI30_13850	COG4783	chaperone-mediated protein folding
GWI30_13870	COG0675	Transposase, IS605 OrfB family
GWI30_13895	COG3842	ATPase activity
GWI30_13900	COG3833	ABC-type maltose transport systems, permease component
GWI30_13905	COG1175	transmembrane transport
GWI30_13910	COG2182	Extracellular solute-binding protein
GWI30_13915	COG3081	Nucleoid-associated protein
GWI30_13920	COG3082	Protein of unknown function (DUF1414)
GWI30_13925	COG3083	sulfuric ester hydrolase activity
GWI30_13930	COG4206	TonB-dependent receptor
GWI30_13935	COG1770	oligopeptidase
GWI30_13955	COG4574	serine-type endopeptidase inhibitor activity
GWI30_13960	COG3085	chromosome segregation
GWI30_13970	COG0287	Prephenate dehydrogenase
GWI30_13970	COG1605	Chorismate mutase
GWI30_13975	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
GWI30_13980	COG0584	glycerophosphoryl diester phosphodiesterase
GWI30_13990	COG1349	DNA-binding transcription factor activity
GWI30_14000	COG5433	transposase activity
GWI30_14010	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
GWI30_14015	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
GWI30_14020	COG0583	DNA-binding transcription factor activity
GWI30_14045	COG0656	L-ascorbic acid biosynthetic process
GWI30_14050	COG2814	Major facilitator Superfamily
GWI30_14060	COG1294	oxidase, subunit
GWI30_14070	COG3385	transposase activity
GWI30_14075	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GWI30_14090	COG1595	DNA-templated transcription, initiation
GWI30_14110	COG2979	Protein of unknown function (DUF533)
GWI30_14145	COG2807	transmembrane transport
GWI30_14150	COG1187	pseudouridine synthase activity
GWI30_14155	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
GWI30_14180	COG5433	transposase activity
GWI30_14195	COG3385	transposase activity
GWI30_14225	COG1166	arginine decarboxylase activity
GWI30_14235	COG2195	Cleaves the N-terminal amino acid of tripeptides
GWI30_14250	COG0675	Transposase, IS605 OrfB family
GWI30_14275	COG0583	DNA-binding transcription factor activity
GWI30_14285	COG2759	Belongs to the formate--tetrahydrofolate ligase family
GWI30_14295	COG0840	transmembrane signaling receptor activity
GWI30_14300	COG0302	gtp cyclohydrolase
GWI30_14310	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
GWI30_14315	COG0596	Alpha beta hydrolase
GWI30_14320	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
GWI30_14335	COG0314	molybdopterin synthase activity
GWI30_14340	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
GWI30_14345	COG0315	cyclic pyranopterin monophosphate synthase activity
GWI30_14350	COG0521	Mo-molybdopterin cofactor biosynthetic process
GWI30_14355	COG3005	denitrification pathway
GWI30_14365	COG0348	domain, Protein
GWI30_14370	COG0437	4 iron, 4 sulfur cluster binding
GWI30_14375	COG0243	molybdopterin cofactor binding
GWI30_14385	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
GWI30_14390	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
GWI30_14395	COG3850	Histidine kinase
GWI30_14400	COG2197	response regulator
GWI30_14425	COG0391	Required for morphogenesis under gluconeogenic growth conditions
GWI30_14435	COG0121	glutamine amidotransferase
GWI30_14440	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
GWI30_14445	COG1960	acyl-CoA dehydrogenase activity
GWI30_14450	COG0784	Response regulator, receiver
GWI30_14450	COG3437	response regulator, receiver
GWI30_14460	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
GWI30_14465	COG4974	Belongs to the 'phage' integrase family
GWI30_14495	COG0328	RNA-DNA hybrid ribonuclease activity
GWI30_14500	COG2226	methyltransferase
GWI30_14505	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GWI30_14510	COG0741	lytic transglycosylase activity
GWI30_14510	COG1388	LysM domain
GWI30_14525	COG1607	acyl-coa hydrolase
GWI30_14540	COG0741	lytic transglycosylase activity
GWI30_14550	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
GWI30_14575	COG0729	surface antigen
GWI30_14585	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
GWI30_14595	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
GWI30_14605	COG4134	Bacterial extracellular solute-binding protein
GWI30_14615	COG4136	ATPase activity
GWI30_14620	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
GWI30_14625	COG2951	lytic endotransglycosylase activity
GWI30_14630	COG1846	Transcriptional regulator
GWI30_14640	COG0033	Phosphoglucomutase
GWI30_14645	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
GWI30_14650	COG0596	Alpha beta hydrolase
GWI30_14665	COG0716	FMN binding
GWI30_14675	COG0735	belongs to the Fur family
GWI30_14680	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
GWI30_14690	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GWI30_14690	COG1263	PTS System
GWI30_14690	COG2190	(PTS) system
GWI30_14695	COG0363	glucosamine-6-phosphate deaminase activity
GWI30_14700	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
GWI30_14705	COG1940	carbohydrate kinase activity
GWI30_14705	COG1846	Transcriptional regulator
GWI30_14715	COG0217	transcriptional regulatory protein
GWI30_14720	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
GWI30_14730	COG1801	Protein of unknown function DUF72
GWI30_14735	COG4106	trans-aconitate 2-methyltransferase activity
GWI30_14740	COG0500	methyltransferase
GWI30_14760	COG0583	DNA-binding transcription factor activity
GWI30_14765	COG0791	NLP P60 protein
GWI30_14780	COG1309	transcriptional regulator
GWI30_14815	COG0534	Mate efflux family protein
GWI30_14825	COG2841	Protein conserved in bacteria
GWI30_14830	COG0674	pyruvate-flavodoxin oxidoreductase activity
GWI30_14830	COG1013	pyruvate-flavodoxin oxidoreductase activity
GWI30_14830	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
GWI30_14830	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
GWI30_14840	COG3217	Mosc domain protein beta barrel domain protein
GWI30_14840	COG0633	Ferredoxin
GWI30_14840	COG0633	Ferredoxin
GWI30_14840	COG3217	Mosc domain protein beta barrel domain protein
GWI30_14845	COG0501	Belongs to the peptidase M48B family
GWI30_14850	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
GWI30_14855	COG1073	alpha beta
GWI30_14855	COG2226	methyltransferase
GWI30_14860	COG0156	8-amino-7-oxononanoate synthase activity
GWI30_14865	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
GWI30_14885	COG0017	Asparaginyl-tRNA synthetase
GWI30_14890	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
GWI30_14905	COG1393	Belongs to the ArsC family
GWI30_14910	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
GWI30_14915	COG1876	peptidase activity
GWI30_14925	COG3263	regulation of cellular component size
GWI30_14940	COG1280	lysine exporter protein (LysE YggA)
GWI30_14970	COG0564	pseudouridine synthase activity
GWI30_14985	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
GWI30_15010	COG2867	negative regulation of translational initiation
GWI30_15015	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
GWI30_15025	COG0582	viral genome integration into host DNA
GWI30_15085	COG3153	acetyltransferase
GWI30_15120	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
GWI30_15130	COG0745	RESPONSE REGULATOR receiver
GWI30_15145	COG4988	ABC transporter
GWI30_15150	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
GWI30_15170	COG1720	tRNA m6t6A37 methyltransferase activity
GWI30_15185	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
GWI30_15190	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
GWI30_15195	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
GWI30_15205	COG2190	(PTS) system
GWI30_15210	COG3038	cytochrome b561
GWI30_15225	COG0420	3'-5' exonuclease activity
GWI30_15230	COG0456	acetyltransferase
GWI30_15235	COG2974	May be involved in recombination
GWI30_15250	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
GWI30_15255	COG1917	Cupin 2, conserved barrel domain protein
GWI30_15255	COG1396	sequence-specific DNA binding
GWI30_15270	COG0531	amino acid
GWI30_15275	COG0531	amino acid
GWI30_15285	COG1283	sodium-dependent phosphate transmembrane transporter activity
GWI30_15295	COG3384	dioxygenase
GWI30_15300	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GWI30_15300	COG2205	protein histidine kinase activity
GWI30_15310	COG5433	transposase activity
GWI30_15330	COG2205	protein histidine kinase activity
GWI30_15330	COG0784	Response regulator, receiver
GWI30_15380	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
GWI30_15390	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
GWI30_15405	COG4263	nitrous-oxide reductase activity
GWI30_15410	COG0348	domain, Protein
GWI30_15410	COG3901	Regulator of nitric oxide reductase transcription
GWI30_15430	COG1376	ErfK ybiS ycfS ynhG family protein
GWI30_15430	COG1388	LysM domain
GWI30_15445	COG3129	Specifically methylates the adenine in position 1618 of 23S rRNA
GWI30_15450	COG0791	NLP P60 protein
GWI30_15460	COG3118	belongs to the thioredoxin family
GWI30_15470	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
GWI30_15475	COG0788	formyltetrahydrofolate deformylase activity
GWI30_15500	COG0739	heme binding
GWI30_15500	COG0741	lytic transglycosylase activity
GWI30_15500	COG1196	nuclear chromosome segregation
GWI30_15505	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
GWI30_15510	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
GWI30_15515	COG0673	inositol 2-dehydrogenase activity
GWI30_15535	COG1032	radical SAM domain protein
GWI30_15540	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
GWI30_15550	COG3706	GGDEF domain
GWI30_15555	COG1752	Esterase of the alpha-beta hydrolase superfamily
GWI30_15560	COG0733	neurotransmitter:sodium symporter activity
GWI30_15580	COG3385	transposase activity
GWI30_15595	COG3328	transposase activity
GWI30_15605	COG0281	malic enzyme
GWI30_15615	COG0534	Mate efflux family protein
GWI30_15630	COG2233	PERMEase
GWI30_15635	COG0095	Lipoate-protein ligase
GWI30_15640	COG1115	amino acid carrier protein
GWI30_15645	COG0019	diaminopimelate decarboxylase activity
GWI30_15655	COG0678	peroxiredoxin activity
GWI30_15660	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
GWI30_15670	COG1126	abc transporter atp-binding protein
GWI30_15675	COG0765	amino acid transport
GWI30_15680	COG4597	amino acid ABC transporter
GWI30_15685	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GWI30_15700	COG1131	(ABC) transporter
GWI30_15705	COG0545	Peptidyl-prolyl cis-trans isomerase
GWI30_15720	COG3142	Participates in the control of copper homeostasis
GWI30_15725	COG1940	carbohydrate kinase activity
GWI30_15745	COG5002	protein histidine kinase activity
GWI30_15750	COG0745	RESPONSE REGULATOR receiver
GWI30_15755	COG0346	lactoylglutathione lyase activity
GWI30_15760	COG3706	GGDEF domain
GWI30_15765	COG3284	Transcriptional regulator
GWI30_15770	COG1012	belongs to the aldehyde dehydrogenase family
GWI30_15780	COG0697	spore germination
GWI30_15790	COG3290	protein histidine kinase activity
GWI30_15795	COG0281	malic enzyme
GWI30_15810	COG1566	PFAM secretion protein HlyD family protein
GWI30_15840	COG0602	queuosine metabolic process
GWI30_15845	COG1328	CTP reductase activity
GWI30_15855	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
GWI30_15860	COG3115	cell septum assembly
GWI30_15865	COG1196	nuclear chromosome segregation
GWI30_15875	COG2860	membrane
GWI30_15885	COG3108	Peptidase M15
GWI30_15890	COG2989	Protein conserved in bacteria
GWI30_15905	COG0463	Glycosyl transferase, family 2
GWI30_15925	COG0366	Alpha amylase catalytic
GWI30_15960	COG3706	GGDEF domain
GWI30_15965	COG0037	tRNA processing
GWI30_15970	COG3590	peptidase
GWI30_15995	COG0531	amino acid
GWI30_16000	COG0814	amino acid
GWI30_16005	COG0583	DNA-binding transcription factor activity
GWI30_16015	COG0825	malonyl-CoA metabolic process
GWI30_16025	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
GWI30_16030	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
GWI30_16035	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
GWI30_16040	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
GWI30_16045	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
GWI30_16060	COG0750	zinc metalloprotease
GWI30_16065	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
GWI30_16070	COG0575	Belongs to the CDS family
GWI30_16075	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
GWI30_16080	COG0233	cytoplasmic translational termination
GWI30_16085	COG0528	UMP kinase activity
GWI30_16090	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
GWI30_16095	COG0052	Belongs to the universal ribosomal protein uS2 family
GWI30_16100	COG0024	Methionine aminopeptidase
GWI30_16105	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
GWI30_16110	COG2171	N-acyltransferase activity
GWI30_16120	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GWI30_16120	COG1263	PTS System
GWI30_16130	COG4580	involved in the transport of maltose and maltodextrins
GWI30_16135	COG5433	transposase activity
GWI30_16145	COG0564	pseudouridine synthase activity
GWI30_16150	COG3098	single-species biofilm formation
GWI30_16175	COG5595	Zn-ribbon-containing, possibly nucleic-acid-binding protein (DUF2310)
GWI30_16185	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
GWI30_16185	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
GWI30_16195	COG3706	GGDEF domain
GWI30_16200	COG1611	Belongs to the LOG family
GWI30_16205	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
GWI30_16210	COG0473	3-isopropylmalate dehydrogenase activity
GWI30_16220	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
GWI30_16225	COG2363	Small membrane protein
GWI30_16235	COG0583	DNA-binding transcription factor activity
GWI30_16245	COG5433	transposase activity
GWI30_16255	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
GWI30_16270	COG1477	protein flavinylation
GWI30_16275	COG2871	sodium ion transport
GWI30_16280	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
GWI30_16285	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
GWI30_16290	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
GWI30_16295	COG1805	sodium ion transport
GWI30_16300	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
GWI30_16305	COG0271	Belongs to the BolA IbaG family
GWI30_16310	COG2813	Specifically methylates the guanine in position
GWI30_16320	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
GWI30_16330	COG2211	Major facilitator Superfamily
GWI30_16335	COG3248	Nucleoside-binding outer membrane protein
GWI30_16340	COG1666	GTP binding
GWI30_16360	COG1484	DNA-dependent DNA replication
GWI30_16365	COG4584	PFAM Integrase catalytic
GWI30_16420	COG3501	Rhs element vgr protein
GWI30_16435	COG2771	luxR family
GWI30_16440	COG0659	secondary active sulfate transmembrane transporter activity
GWI30_16465	COG1393	Belongs to the ArsC family
GWI30_16470	COG0798	PFAM Bile acid sodium symporter
GWI30_16480	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
GWI30_16505	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
GWI30_16510	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
GWI30_16515	COG1151	hydroxylamine reductase activity
GWI30_16520	COG0783	Belongs to the Dps family
GWI30_16545	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
GWI30_16560	COG0300	oxidoreductase activity
GWI30_16570	COG0415	Belongs to the DNA photolyase family
GWI30_16575	COG0789	Transcriptional regulator
GWI30_16580	COG3272	Protein of unknown function (DUF1722)
GWI30_16605	COG0077	Prephenate dehydratase
GWI30_16605	COG1605	Chorismate mutase
GWI30_16630	COG4580	involved in the transport of maltose and maltodextrins
GWI30_16650	COG4580	involved in the transport of maltose and maltodextrins
GWI30_16655	COG3940	Belongs to the glycosyl hydrolase 43 family
GWI30_16670	COG1175	transmembrane transport
GWI30_16690	COG1609	Transcriptional regulator
GWI30_16705	COG2133	pyrroloquinoline quinone binding
GWI30_16715	COG1349	DNA-binding transcription factor activity
GWI30_16720	COG2084	Dehydrogenase
GWI30_16725	COG3395	kinase activity
GWI30_16730	COG0235	Class ii aldolase
GWI30_16735	COG3622	Belongs to the hyi family
GWI30_16740	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GWI30_16745	COG2610	gluconate transmembrane transporter activity
GWI30_16765	COG0300	oxidoreductase activity
GWI30_16790	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
GWI30_16810	COG3813	Protein conserved in bacteria
GWI30_16820	COG0826	peptidase U32
GWI30_16830	COG1280	lysine exporter protein (LysE YggA)
GWI30_16865	COG2200	EAL domain
GWI30_16865	COG2203	Gaf domain
GWI30_16865	COG2199	diguanylate cyclase activity
GWI30_16905	COG0114	fumarate hydratase activity
GWI30_16920	COG5433	transposase activity
GWI30_16935	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
GWI30_16990	COG0545	Peptidyl-prolyl cis-trans isomerase
GWI30_17005	COG1047	Peptidyl-prolyl cis-trans
GWI30_17010	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
GWI30_17020	COG0784	Response regulator, receiver
GWI30_17020	COG0835	chemotaxis
GWI30_17025	COG0429	hydrolase of the alpha beta-hydrolase fold
GWI30_17035	COG3089	Belongs to the UPF0270 family
GWI30_17040	COG3954	Phosphoribulokinase
GWI30_17055	COG1765	OsmC-like protein
GWI30_17090	COG2205	protein histidine kinase activity
GWI30_17095	COG2814	Major facilitator Superfamily
GWI30_17130	COG0748	coenzyme F420 binding
GWI30_17135	COG3721	Heme iron utilization protein
GWI30_17145	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GWI30_17170	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
GWI30_17180	COG0463	Glycosyl transferase, family 2
GWI30_17185	COG0741	lytic transglycosylase activity
GWI30_17190	COG0488	(ABC) transporter
GWI30_17200	COG2252	PERMEase
GWI30_17205	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
GWI30_17210	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
GWI30_17215	COG3178	'Phosphotransferase
GWI30_17220	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
GWI30_17230	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
GWI30_17235	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
GWI30_17240	COG2967	ApaG domain
GWI30_17245	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
GWI30_17265	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GWI30_17270	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
GWI30_17280	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
GWI30_17285	COG0211	Belongs to the bacterial ribosomal protein bL27 family
GWI30_17290	COG0261	This protein binds to 23S rRNA in the presence of protein L20
GWI30_17295	COG0142	geranyltranstransferase activity
GWI30_17300	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
GWI30_17305	COG0330	HflC and HflK could
GWI30_17310	COG0330	HflC and HflK could
GWI30_17315	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
GWI30_17320	COG1923	regulation of RNA biosynthetic process
GWI30_17325	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
GWI30_17330	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
GWI30_17340	COG0802	atpase or kinase
GWI30_17345	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
GWI30_17345	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
GWI30_17365	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
GWI30_17370	COG2011	ABC-type metal ion transport system permease component
GWI30_17375	COG1464	Belongs to the NlpA lipoprotein family
GWI30_17390	COG0840	transmembrane signaling receptor activity
GWI30_17415	COG5433	transposase activity
GWI30_17425	COG3039	Transposase
GWI30_17430	COG5433	transposase activity
GWI30_17445	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GWI30_17450	COG1376	ErfK ybiS ycfS ynhG family protein
GWI30_17455	COG0668	transmembrane transport
GWI30_17465	COG2731	YhcH YjgK YiaL family protein
GWI30_17480	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GWI30_17495	COG5433	transposase activity
GWI30_17505	COG0477	Major facilitator Superfamily
GWI30_17525	COG0569	domain protein
GWI30_17525	COG2985	domain, Protein
GWI30_17530	COG1272	protein, Hemolysin III
GWI30_17535	COG0076	glutamate decarboxylase activity
GWI30_17540	COG2917	probably involved in intracellular septation
GWI30_17545	COG2350	Protein conserved in bacteria
GWI30_17555	COG1555	photosystem II stabilization
GWI30_17560	COG1210	Utp--glucose-1-phosphate uridylyltransferase
GWI30_17565	COG3104	oligopeptide transport
GWI30_17570	COG0745	RESPONSE REGULATOR receiver
GWI30_17600	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GWI30_17610	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
GWI30_17615	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
GWI30_17655	COG0316	Belongs to the HesB IscA family
GWI30_17665	COG0038	chloride channel
GWI30_17670	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
GWI30_17690	COG0671	phosphoesterase, PA-phosphatase related
GWI30_17700	COG0583	DNA-binding transcription factor activity
GWI30_17705	COG2076	Multidrug Resistance protein
GWI30_17715	COG0346	lactoylglutathione lyase activity
GWI30_17720	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
GWI30_17725	COG1643	Atp-dependent helicase
GWI30_17730	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
GWI30_17735	COG1489	DNA binding
GWI30_17740	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
GWI30_17745	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
GWI30_17750	COG0617	tRNA 3'-terminal CCA addition
GWI30_17760	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
GWI30_17765	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
GWI30_17775	COG0842	Transport permease protein
GWI30_17780	COG1131	(ABC) transporter
GWI30_17795	COG3385	transposase activity
GWI30_17805	COG0163	prenyltransferase activity
GWI30_17810	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
GWI30_17815	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
GWI30_17830	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
GWI30_17865	COG0840	transmembrane signaling receptor activity
GWI30_17875	COG3385	transposase activity
GWI30_17885	COG0529	Catalyzes the synthesis of activated sulfate
GWI30_17890	COG0471	metal ion transport
GWI30_17890	COG3273	potassium ion transport
GWI30_17895	COG2895	sulfate adenylyltransferase (ATP) activity
GWI30_17910	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
GWI30_17910	COG1648	precorrin-2 dehydrogenase activity
GWI30_17915	COG0330	HflC and HflK could
GWI30_17920	COG1585	Membrane protein implicated in regulation of membrane protease activity
GWI30_17930	COG0673	inositol 2-dehydrogenase activity
GWI30_17940	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
GWI30_17945	COG0635	Involved in the biosynthesis of porphyrin-containing compound
GWI30_17950	COG3036	rescue of stalled ribosome
GWI30_17970	COG0138	bifunctional purine biosynthesis protein purh
GWI30_17975	COG0151	Belongs to the GarS family
GWI30_18000	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
GWI30_18005	COG0358	DNA primase activity
GWI30_18010	COG1610	YqeY-like protein
GWI30_18015	COG0828	Belongs to the bacterial ribosomal protein bS21 family
GWI30_18020	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
GWI30_18035	COG3039	Transposase
GWI30_18040	COG4942	peptidase
GWI30_18040	COG1388	LysM domain
GWI30_18045	COG1238	metal cluster binding
GWI30_18050	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
GWI30_18055	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
GWI30_18060	COG0585	pseudouridine synthase activity
GWI30_18070	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
GWI30_18075	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
GWI30_18080	COG0148	phosphopyruvate hydratase activity
GWI30_18085	COG0504	CTP synthase activity
GWI30_18090	COG3956	TIGRFAM MazG family protein
GWI30_18095	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
GWI30_18100	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
GWI30_18110	COG4807	Protein conserved in bacteria
GWI30_18115	COG3023	N-Acetylmuramoyl-L-alanine amidase
GWI30_18120	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
GWI30_18125	COG1381	Involved in DNA repair and RecF pathway recombination
GWI30_18135	COG0571	ribonuclease III activity
GWI30_18140	COG0681	Belongs to the peptidase S26 family
GWI30_18145	COG0481	GTPase activity
GWI30_18165	COG1595	DNA-templated transcription, initiation
GWI30_18170	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
GWI30_18220	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
GWI30_18225	COG0191	fructose-bisphosphate aldolase activity
GWI30_18230	COG0126	phosphoglycerate kinase activity
GWI30_18235	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
GWI30_18240	COG1940	carbohydrate kinase activity
GWI30_18245	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
GWI30_18255	COG4991	sh3 domain protein
GWI30_18260	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
GWI30_18275	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
GWI30_18280	COG1028	Short-chain dehydrogenase reductase Sdr
GWI30_18290	COG1505	serine-type exopeptidase activity
GWI30_18295	COG3174	membrane
GWI30_18300	COG0110	maltose O-acetyltransferase activity
GWI30_18325	COG3039	Transposase
GWI30_18330	COG0165	Argininosuccinate lyase
GWI30_18335	COG0137	argininosuccinate synthase activity
GWI30_18345	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
GWI30_18350	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
GWI30_18360	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
GWI30_18365	COG3447	MASE1 domain protein
GWI30_18365	COG5001	Diguanylate cyclase
GWI30_18365	COG5002	protein histidine kinase activity
GWI30_18410	COG0583	DNA-binding transcription factor activity
GWI30_18415	COG1380	Effector of murein hydrolase LrgA
GWI30_18420	COG1346	cytolysis
GWI30_18425	COG0460	homoserine dehydrogenase
GWI30_18425	COG0527	aspartate kinase activity
GWI30_18430	COG0626	cystathionine gamma-synthase activity
GWI30_18445	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GWI30_18450	COG0814	amino acid
GWI30_18455	COG1218	3'(2'),5'-bisphosphate nucleotidase
GWI30_18460	COG0494	nUDIX hydrolase
GWI30_18465	COG1011	Hydrolase
GWI30_18475	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
GWI30_18490	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
GWI30_18500	COG3156	type II secretion system protein K
GWI30_18510	COG4795	General secretion pathway protein
GWI30_18515	COG2165	general secretion pathway protein
GWI30_18525	COG2165	general secretion pathway protein
GWI30_18530	COG1459	type II secretion system
GWI30_18535	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
GWI30_18545	COG3031	protein transport across the cell outer membrane
GWI30_18555	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
GWI30_18560	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
GWI30_18580	COG3133	Outer membrane lipoprotein
GWI30_18590	COG1392	Phosphate transport regulator
GWI30_18595	COG0306	phosphate transporter
GWI30_18600	COG0617	tRNA 3'-terminal CCA addition
GWI30_18605	COG3409	Peptidoglycan-binding domain 1 protein
GWI30_18605	COG3267	Type II secretory pathway component ExeA
GWI30_18615	COG1194	a g-specific adenine glycosylase
GWI30_18620	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
GWI30_18635	COG3240	lipase activity
GWI30_18645	COG3009	Protein conserved in bacteria
GWI30_18650	COG3008	intermembrane lipid transfer
GWI30_18650	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
GWI30_18655	COG2995	paraquat-inducible protein a
GWI30_18665	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
GWI30_18670	COG5001	Diguanylate cyclase
GWI30_18670	COG4251	negative regulation of phosphorylation
GWI30_18670	COG2203	Gaf domain
GWI30_18670	COG3706	GGDEF domain
GWI30_18675	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
GWI30_18680	COG2813	Specifically methylates the guanine in position
GWI30_18685	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
GWI30_18690	COG0297	glycogen (starch) synthase activity
GWI30_18730	COG1757	Na H antiporter
GWI30_18735	COG0583	DNA-binding transcription factor activity
GWI30_18740	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
GWI30_18745	COG3842	ATPase activity
GWI30_18750	COG1176	ABC-type spermidine putrescine transport system, permease component I
GWI30_18755	COG1177	transmembrane transport
GWI30_18760	COG1012	belongs to the aldehyde dehydrogenase family
GWI30_18765	COG0109	protoheme IX farnesyltransferase activity
GWI30_18770	COG1612	heme a metabolic process
GWI30_18795	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
GWI30_18800	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
GWI30_18805	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
GWI30_18810	COG1444	tRNA N-acetyltransferase activity
GWI30_18830	COG1803	Methylglyoxal synthase
GWI30_18845	COG0252	asparaginase activity
GWI30_18855	COG1609	Transcriptional regulator
GWI30_18865	COG1940	carbohydrate kinase activity
GWI30_18870	COG1447	Phosphotransferase system cellobiose-specific component IIA
GWI30_18875	COG2723	6-phospho-beta-galactosidase activity
GWI30_18880	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
GWI30_18880	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
GWI30_18885	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
GWI30_18890	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
GWI30_18905	COG1263	PTS System
GWI30_18905	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GWI30_18910	COG0366	Alpha amylase catalytic
GWI30_18915	COG0110	maltose O-acetyltransferase activity
GWI30_18920	COG1522	sequence-specific DNA binding
GWI30_18935	COG3385	transposase activity
GWI30_18970	COG1484	DNA-dependent DNA replication
GWI30_18975	COG4584	PFAM Integrase catalytic
GWI30_19005	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
GWI30_19010	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
GWI30_19025	COG0477	Major facilitator Superfamily
GWI30_19030	COG0523	cobalamin synthesis protein
GWI30_19040	COG1280	lysine exporter protein (LysE YggA)
GWI30_19050	COG2200	EAL domain
GWI30_19055	COG1049	propionate catabolic process, 2-methylcitrate cycle
GWI30_19060	COG1752	Esterase of the alpha-beta hydrolase superfamily
GWI30_19065	COG0840	transmembrane signaling receptor activity
GWI30_19080	COG3706	GGDEF domain
GWI30_19085	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
GWI30_19090	COG0508	dehydrogenase complex catalyzes the overall conversion of
GWI30_19095	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
GWI30_19100	COG2186	Transcriptional regulator
GWI30_19125	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
GWI30_19130	COG1459	type II secretion system
GWI30_19135	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
GWI30_19145	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
GWI30_19150	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
GWI30_19160	COG0653	protein targeting
GWI30_19170	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
GWI30_19175	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
GWI30_19180	COG0849	cell division
GWI30_19185	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
GWI30_19190	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
GWI30_19195	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
GWI30_19200	COG0772	Belongs to the SEDS family
GWI30_19205	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
GWI30_19210	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
GWI30_19215	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
GWI30_19220	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
GWI30_19225	COG0768	penicillin binding
GWI30_19230	COG3116	cell division
GWI30_19235	COG0275	rRNA processing
GWI30_19240	COG2001	Belongs to the MraZ family
GWI30_19250	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
GWI30_19255	COG3107	peptidoglycan biosynthetic process
GWI30_19260	COG0792	nuclease activity
GWI30_19265	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
GWI30_19270	COG2823	Periplasmic or secreted lipoprotein
GWI30_19275	COG2969	positive regulation of protein catabolic process
GWI30_19280	COG0625	glutathione transferase activity
GWI30_19285	COG2857	Cytochrome c1
GWI30_19290	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
GWI30_19295	COG0723	plastoquinol--plastocyanin reductase activity
GWI30_19300	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GWI30_19305	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
GWI30_19310	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
GWI30_19320	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GWI30_19325	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GWI30_19335	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
GWI30_19340	COG1660	Displays ATPase and GTPase activities
GWI30_19345	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
GWI30_19360	COG1137	ATPase activity
GWI30_19365	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
GWI30_19370	COG3117	lipopolysaccharide transmembrane transporter activity
GWI30_19375	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
GWI30_19380	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
GWI30_19380	COG0517	IMP dehydrogenase activity
GWI30_19385	COG1127	ABC transporter
GWI30_19390	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
GWI30_19395	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
GWI30_19400	COG2854	intermembrane phospholipid transfer
GWI30_19410	COG5007	Belongs to the BolA IbaG family
GWI30_19415	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
GWI30_19420	COG0312	modulator of DNA gyrase
GWI30_19425	COG3028	Belongs to the UPF0307 family
GWI30_19445	COG2926	Belongs to the UPF0265 family
GWI30_19475	COG1396	sequence-specific DNA binding
GWI30_19480	COG3135	benzoate transporter
GWI30_19490	COG1522	sequence-specific DNA binding
GWI30_19500	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
GWI30_19510	COG1058	Belongs to the CinA family
GWI30_19510	COG1546	Belongs to the CinA family
GWI30_19515	COG1988	membrane-bound metal-dependent
GWI30_19525	COG0561	phosphatase activity
GWI30_19530	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
GWI30_19540	COG1011	Hydrolase
GWI30_19555	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
GWI30_19560	COG0019	diaminopimelate decarboxylase activity
GWI30_19570	COG1965	Belongs to the frataxin family
GWI30_19575	COG0400	carboxylic ester hydrolase activity
GWI30_19580	COG3072	Adenylate cyclase
GWI30_19585	COG0181	hydroxymethylbilane synthase activity
GWI30_19595	COG2959	enzyme of heme biosynthesis
GWI30_19600	COG3071	HemY protein
GWI30_19610	COG1494	fructose-1,6-bisphosphatase
GWI30_19620	COG1247	-acetyltransferase
GWI30_19640	COG1733	regulation of RNA biosynthetic process
GWI30_19660	COG3932	Exopolysaccharide synthesis, ExoD
GWI30_19665	COG3706	GGDEF domain
GWI30_19690	COG3039	Transposase
GWI30_19695	COG3385	transposase activity
GWI30_19700	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
GWI30_19705	COG2022	thiamine diphosphate biosynthetic process
GWI30_19715	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
GWI30_19720	COG0352	thiamine-phosphate diphosphorylase activity
GWI30_19725	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
GWI30_19740	COG0745	RESPONSE REGULATOR receiver
GWI30_19745	COG0642	Histidine kinase
GWI30_19750	COG0189	ligase activity
GWI30_19780	COG2321	neutral zinc metallopeptidase
GWI30_19790	COG0477	Major facilitator Superfamily
GWI30_19805	COG0312	modulator of DNA gyrase
GWI30_19810	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
GWI30_19815	COG3164	Protein of unknown function
GWI30_19820	COG1530	ribonuclease E activity
GWI30_19825	COG0424	maF-like protein
GWI30_19830	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
GWI30_19835	COG1792	Involved in formation and maintenance of cell shape
GWI30_19840	COG1077	Cell shape determining protein MreB Mrl
GWI30_19850	COG3385	transposase activity
GWI30_19900	COG1459	type II secretion system
GWI30_19905	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
GWI30_19950	COG2200	EAL domain
GWI30_19950	COG2199	diguanylate cyclase activity
GWI30_19955	COG3385	transposase activity
GWI30_19960	COG2200	EAL domain
GWI30_19965	COG0387	Pfam Sodium calcium exchanger
GWI30_19970	COG2986	histidine ammonia-lyase
GWI30_19975	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
GWI30_19980	COG0010	Belongs to the arginase family
GWI30_19985	COG1228	amidohydrolase
GWI30_19990	COG2188	Transcriptional regulator
GWI30_19995	COG0288	reversible hydration of carbon dioxide
GWI30_20005	COG2177	Part of the ABC transporter FtsEX involved in
GWI30_20010	COG2884	Cell division ATP-binding protein ftsE
GWI30_20015	COG0552	protein localization to endoplasmic reticulum
GWI30_20020	COG0742	ribosomal rna small subunit methyltransferase
GWI30_20045	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
GWI30_20050	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
GWI30_20060	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
GWI30_20070	COG2095	MarC family integral membrane protein
GWI30_20080	COG1301	dicarboxylic acid transport
GWI30_20105	COG3385	transposase activity
GWI30_20110	COG3714	YhhN family
GWI30_20135	COG1770	oligopeptidase
GWI30_20150	COG2249	NAD(P)H dehydrogenase (quinone) activity
GWI30_20205	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
GWI30_20210	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
GWI30_20215	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
GWI30_20220	COG0049	tRNA binding
GWI30_20225	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
GWI30_20230	COG2168	tRNA wobble position uridine thiolation
GWI30_20250	COG2964	Protein conserved in bacteria
GWI30_20255	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
GWI30_20260	COG0085	RNA polymerase activity
GWI30_20265	COG0222	ribosome binding
GWI30_20270	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
GWI30_20275	COG0081	regulation of translation
GWI30_20280	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
GWI30_20285	COG0250	Participates in transcription elongation, termination and antitermination
GWI30_20300	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
GWI30_20325	COG0812	UDP-N-acetylmuramate dehydrogenase activity
GWI30_20330	COG0569	domain protein
GWI30_20335	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
GWI30_20340	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
GWI30_20345	COG3005	denitrification pathway
GWI30_20350	COG0243	molybdopterin cofactor binding
GWI30_20360	COG2205	protein histidine kinase activity
GWI30_20365	COG0745	RESPONSE REGULATOR receiver
GWI30_20380	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
GWI30_20400	COG2204	response regulator
GWI30_20410	COG2205	protein histidine kinase activity
GWI30_20430	COG0517	IMP dehydrogenase activity
GWI30_20430	COG0516	GMP reductase activity
GWI30_20435	COG5413	integral membrane protein
GWI30_20445	COG1522	sequence-specific DNA binding
GWI30_20450	COG2502	aspartate--ammonia ligase
GWI30_20455	COG0542	response to heat
GWI30_20465	COG0564	pseudouridine synthase activity
GWI30_20470	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
GWI30_20475	COG0446	pyridine nucleotide-disulphide oxidoreductase
GWI30_20485	COG3681	Belongs to the UPF0597 family
GWI30_20490	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
GWI30_20495	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
GWI30_20500	COG1979	alcohol dehydrogenase
GWI30_20505	COG2207	Transcriptional regulator
GWI30_20510	COG3040	lipid binding
GWI30_20525	COG0688	phosphatidylethanolamine metabolic process
GWI30_20540	COG0540	Belongs to the ATCase OTCase family
GWI30_20545	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
GWI30_20550	COG1438	arginine binding
GWI30_20555	COG1288	antiporter activity
GWI30_20560	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
GWI30_20590	COG4211	Belongs to the binding-protein-dependent transport system permease family
GWI30_20605	COG3250	beta-galactosidase activity
GWI30_20610	COG1609	Transcriptional regulator
GWI30_20615	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
GWI30_20625	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
GWI30_20630	COG2017	converts alpha-aldose to the beta-anomer
GWI30_20635	COG0667	Aldo Keto reductase
GWI30_20640	COG1968	undecaprenyl-diphosphatase activity
GWI30_20645	COG3806	Anti-sigma factor
GWI30_20650	COG1595	DNA-templated transcription, initiation
GWI30_20660	COG0018	arginyl-trna synthetase
GWI30_20670	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
GWI30_20675	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
GWI30_20695	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GWI30_20700	COG1131	(ABC) transporter
GWI30_20705	COG0842	Transport permease protein
GWI30_20710	COG0842	Transport permease protein
GWI30_20715	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
GWI30_20725	COG2116	formate transmembrane transporter activity
GWI30_20730	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
GWI30_20730	COG1648	precorrin-2 dehydrogenase activity
GWI30_20735	COG2239	Acts as a magnesium transporter
GWI30_20740	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
GWI30_20745	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
GWI30_20755	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
GWI30_20765	COG0514	ATP-dependent DNA helicase (RecQ)
GWI30_20770	COG2050	protein possibly involved in aromatic compounds catabolism
GWI30_20795	COG2258	MOSC domain
GWI30_20800	COG1177	transmembrane transport
GWI30_20805	COG1176	ABC-type spermidine putrescine transport system, permease component I
GWI30_20810	COG3842	ATPase activity
GWI30_20830	COG0174	glutamine synthetase
GWI30_20850	COG3045	CreA protein
GWI30_20855	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
GWI30_20860	COG0443	Heat shock 70 kDa protein
GWI30_20875	COG0366	Alpha amylase catalytic
GWI30_20890	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
GWI30_20895	COG0745	RESPONSE REGULATOR receiver
GWI30_20900	COG2205	protein histidine kinase activity
GWI30_20915	COG0281	malic enzyme
GWI30_20920	COG0702	epimerase
GWI30_20925	COG0254	rRNA binding
GWI30_20930	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
GWI30_20945	COG3039	Transposase
GWI30_20955	COG0129	dihydroxy-acid dehydratase activity
GWI30_20965	COG3978	acetolactate synthase activity
GWI30_20980	COG0606	chelatase, subunit chli
GWI30_20985	COG0204	Acyl-transferase
GWI30_20990	COG0204	Acyl-transferase
GWI30_20995	COG1683	Conserved Protein
GWI30_21005	COG1335	isochorismatase
GWI30_21015	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
GWI30_21020	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
GWI30_21025	COG3639	organic phosphonate transmembrane transporter activity
GWI30_21030	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
GWI30_21035	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
GWI30_21045	COG3084	Protein conserved in bacteria
GWI30_21050	COG4251	negative regulation of phosphorylation
GWI30_21050	COG2203	Gaf domain
GWI30_21050	COG3706	GGDEF domain
GWI30_21050	COG5001	Diguanylate cyclase
GWI30_21055	COG0789	Transcriptional regulator
GWI30_21065	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
GWI30_21070	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
GWI30_21075	COG1561	YicC-like family, N-terminal region
GWI30_21090	COG1519	Transferase
GWI30_21095	COG0859	PFAM glycosyl transferase family 9
GWI30_21100	COG0463	Glycosyl transferase, family 2
GWI30_21105	COG0859	PFAM glycosyl transferase family 9
GWI30_21110	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
GWI30_21115	COG2990	Protein conserved in bacteria
GWI30_21120	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
GWI30_21130	COG0267	Belongs to the bacterial ribosomal protein bL33 family
GWI30_21135	COG0227	Belongs to the bacterial ribosomal protein bL28 family
GWI30_21140	COG2003	Belongs to the UPF0758 family
GWI30_21145	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
GWI30_21150	COG0756	dUTP diphosphatase activity
GWI30_21155	COG1309	transcriptional regulator
GWI30_21160	COG0668	transmembrane transport
GWI30_21170	COG0166	Belongs to the GPI family
GWI30_21180	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
GWI30_21185	COG0583	DNA-binding transcription factor activity
GWI30_21195	COG1042	CoA-binding domain protein
GWI30_21195	COG0045	succinate-CoA ligase (ADP-forming) activity
GWI30_21195	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GWI30_21225	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
GWI30_21230	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
GWI30_21235	COG1739	Uncharacterized protein family UPF0029
GWI30_21240	COG0006	proline dipeptidase activity
GWI30_21245	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
GWI30_21250	COG1024	Enoyl-CoA hydratase
GWI30_21250	COG1250	3-hydroxyacyl-CoA dehydrogenase
GWI30_21255	COG0183	Belongs to the thiolase family
GWI30_21260	COG0745	RESPONSE REGULATOR receiver
GWI30_21270	COG1653	transport
GWI30_21285	COG0425	Belongs to the sulfur carrier protein TusA family
GWI30_21290	COG0251	oxidation-reduction process
GWI30_21295	COG2885	chlorophyll binding
GWI30_21325	COG2818	Glycosylase
GWI30_21330	COG0752	glycyl-tRNA synthetase alpha subunit
GWI30_21335	COG0751	glycine-tRNA ligase activity
GWI30_21350	COG0814	amino acid
GWI30_21355	COG0814	amino acid
GWI30_21360	COG3039	Transposase
GWI30_21370	COG0348	domain, Protein
GWI30_21380	COG0446	pyridine nucleotide-disulphide oxidoreductase
GWI30_21385	COG0426	domain, Protein
GWI30_21385	COG1773	rubredoxin
GWI30_21390	COG3604	Transcriptional regulator
GWI30_21400	COG1609	Transcriptional regulator
GWI30_21440	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
GWI30_21455	COG2960	long-chain fatty acid transporting porin activity
GWI30_21470	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
GWI30_21485	COG3118	belongs to the thioredoxin family
GWI30_21490	COG0513	Belongs to the DEAD box helicase family
GWI30_21495	COG0248	Ppx GppA phosphatase
GWI30_21510	COG0742	ribosomal rna small subunit methyltransferase
GWI30_21530	COG0084	hydrolase, TatD family'
GWI30_21535	COG0805	protein transport
GWI30_21540	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
GWI30_21545	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
GWI30_21550	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
GWI30_21555	COG3165	ubiquinone biosynthetic process from chorismate
GWI30_21560	COG2226	methyltransferase
GWI30_21565	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
GWI30_21570	COG0402	S-adenosylhomocysteine deaminase activity
GWI30_21575	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
GWI30_21615	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
GWI30_21620	COG0848	biopolymer transport protein
GWI30_21625	COG0811	peptide transport
GWI30_21630	COG0811	peptide transport
GWI30_21645	COG5433	transposase activity
GWI30_21650	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
GWI30_21655	COG1349	DNA-binding transcription factor activity
GWI30_21660	COG0745	RESPONSE REGULATOR receiver
GWI30_21665	COG2205	protein histidine kinase activity
GWI30_21675	COG4452	Inner membrane protein CreD
GWI30_21680	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
GWI30_21685	COG0355	proton-transporting ATP synthase activity, rotational mechanism
GWI30_21690	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
GWI30_21695	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
GWI30_21700	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
GWI30_21705	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
GWI30_21710	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
GWI30_21720	COG0356	it plays a direct role in the translocation of protons across the membrane
GWI30_21730	COG1475	DNA binding
GWI30_21735	COG1192	Involved in chromosome partitioning
GWI30_21740	COG0357	Ribosomal RNA small subunit methyltransferase G
GWI30_21745	COG0445	tRNA wobble uridine modification
GWI30_21750	COG0716	FMN binding
GWI30_21755	COG4774	siderophore transport
GWI30_21760	COG4615	Cyclic peptide transporter
GWI30_21765	COG1120	ATPase activity
GWI30_21770	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
GWI30_21775	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GWI30_21785	COG3550	peptidyl-serine autophosphorylation
GWI30_21825	COG5433	transposase activity
GWI30_21855	COG4974	Belongs to the 'phage' integrase family
GWI30_21860	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
GWI30_21865	COG0706	membrane insertase activity
GWI30_21870	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
GWI30_21875	COG0594	ribonuclease P activity
GWI30_21880	COG0230	Belongs to the bacterial ribosomal protein bL34 family
GWI30_21955	COG5433	transposase activity
GWI30_21990	COG0675	Transposase, IS605 OrfB family
GWI30_22000	COG0210	DNA helicase
GWI30_22055	COG5433	transposase activity
GWI30_22095	COG2801	Transposase and inactivated derivatives
GWI30_22100	COG1397	ADP-ribosylglycohydrolase
GWI30_22105	COG1397	ADP-ribosylglycohydrolase
GWI30_22125	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
GWI30_22130	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
GWI30_22135	COG0629	single-stranded DNA binding
GWI30_22145	COG1199	ATP-dependent helicase activity
GWI30_22155	COG4584	PFAM Integrase catalytic
GWI30_22160	COG1484	DNA-dependent DNA replication
GWI30_22165	COG3328	transposase activity
GWI30_22170	COG5433	transposase activity
GWI30_22190	COG1518	maintenance of DNA repeat elements
GWI30_22195	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
GWI30_22290	COG0675	Transposase, IS605 OrfB family
GWI30_22300	COG3385	transposase activity
GWI30_22310	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
GWI30_22350	COG3385	transposase activity
GWI30_22375	COG0675	Transposase, IS605 OrfB family
GWI30_22445	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
GWI30_22460	COG2189	Belongs to the N(4) N(6)-methyltransferase family
GWI30_22465	COG2189	Belongs to the N(4) N(6)-methyltransferase family
GWI30_22505	COG0783	Belongs to the Dps family
GWI30_22515	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
GWI30_22520	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GWI30_22550	COG1342	Belongs to the UPF0251 family
GWI30_22605	COG4737	Cytotoxic translational repressor of toxin-antitoxin stability system
GWI30_22630	COG0675	Transposase, IS605 OrfB family
GWI30_22690	COG0675	Transposase, IS605 OrfB family
GWI30_22725	COG0629	single-stranded DNA binding
GWI30_22730	COG0675	Transposase, IS605 OrfB family
GWI30_22750	COG0675	Transposase, IS605 OrfB family
GWI30_22825	COG0675	Transposase, IS605 OrfB family
GWI30_22855	COG0675	Transposase, IS605 OrfB family
GWI30_22915	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
GWI30_22945	COG5433	transposase activity
GWI30_22955	COG5001	Diguanylate cyclase
GWI30_22955	COG3300	MHYT domain
GWI30_22975	COG5433	transposase activity
GWI30_23015	COG1695	Transcriptional regulator
GWI30_23035	COG3173	Aminoglycoside phosphotransferase
GWI30_23055	COG1660	Displays ATPase and GTPase activities
GWI30_23085	COG0653	protein targeting
GWI30_23095	COG4584	PFAM Integrase catalytic
GWI30_23100	COG1484	DNA-dependent DNA replication
GWI30_23110	COG5433	transposase activity
GWI30_23125	COG2916	Histone family protein nucleoid-structuring protein H-NS
GWI30_23145	COG0675	Transposase, IS605 OrfB family
GWI30_23190	COG4804	nuclease activity
GWI30_23260	COG4644	lycopene metabolic process
GWI30_23275	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
GWI30_23290	COG1136	(ABC) transporter
GWI30_23305	COG1309	transcriptional regulator
GWI30_23320	COG1192	Involved in chromosome partitioning
GWI30_23325	COG1192	Involved in chromosome partitioning
GWI30_23345	COG2026	Addiction module toxin, RelE StbE family
GWI30_23350	COG3077	Addiction module antitoxin, RelB DinJ family