locus-tag	class	description
WP7W18E02_00010	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
WP7W18E02_00020	COG0592	DNA-directed DNA polymerase activity
WP7W18E02_00040	COG0187	DNA topoisomerase II activity
WP7W18E02_00060	COG2378	regulation of single-species biofilm formation
WP7W18E02_00080	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
WP7W18E02_00090	COG0071	Belongs to the small heat shock protein (HSP20) family
WP7W18E02_00100	COG0071	Belongs to the small heat shock protein (HSP20) family
WP7W18E02_00110	COG3977	Valine--pyruvate aminotransferase
WP7W18E02_00140	COG2814	Major facilitator Superfamily
WP7W18E02_00150	COG0745	RESPONSE REGULATOR receiver
WP7W18E02_00160	COG2205	protein histidine kinase activity
WP7W18E02_00210	COG1733	regulation of RNA biosynthetic process
WP7W18E02_00220	COG2267	carboxylic ester hydrolase activity
WP7W18E02_00230	COG0604	alcohol dehydrogenase
WP7W18E02_00250	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
WP7W18E02_00260	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
WP7W18E02_00260	COG4191	Histidine kinase
WP7W18E02_00270	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
WP7W18E02_00280	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
WP7W18E02_00290	COG1309	transcriptional regulator
WP7W18E02_00310	COG0561	phosphatase activity
WP7W18E02_00320	COG2267	carboxylic ester hydrolase activity
WP7W18E02_00330	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
WP7W18E02_00340	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
WP7W18E02_00350	COG1758	RNA polymerase activity
WP7W18E02_00370	COG0859	PFAM glycosyl transferase family 9
WP7W18E02_00380	COG3642	lipopolysaccharide core region biosynthetic process
WP7W18E02_00460	COG0589	response to stress
WP7W18E02_00470	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
WP7W18E02_00480	COG3706	GGDEF domain
WP7W18E02_00490	COG1528	Iron-storage protein
WP7W18E02_00500	COG2081	HI0933 family
WP7W18E02_00510	COG2223	nitrite transmembrane transporter activity
WP7W18E02_00530	COG3275	phosphorelay sensor kinase activity
WP7W18E02_00540	COG3279	Response regulator of the LytR AlgR family
WP7W18E02_00550	COG2223	nitrite transmembrane transporter activity
WP7W18E02_00560	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
WP7W18E02_00570	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
WP7W18E02_00580	COG4206	TonB-dependent receptor
WP7W18E02_00590	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
WP7W18E02_00620	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
WP7W18E02_00620	COG1042	CoA-binding domain protein
WP7W18E02_00620	COG0045	succinate-CoA ligase (ADP-forming) activity
WP7W18E02_00640	COG0583	DNA-binding transcription factor activity
WP7W18E02_00650	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
WP7W18E02_00660	COG0166	Belongs to the GPI family
WP7W18E02_00680	COG0668	transmembrane transport
WP7W18E02_00690	COG1309	transcriptional regulator
WP7W18E02_00700	COG0756	dUTP diphosphatase activity
WP7W18E02_00720	COG3039	Transposase
WP7W18E02_00830	COG4584	PFAM Integrase catalytic
WP7W18E02_00840	COG1484	DNA-dependent DNA replication
WP7W18E02_00940	COG1538	Outer membrane efflux protein
WP7W18E02_00950	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
WP7W18E02_00960	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
WP7W18E02_00980	COG0745	RESPONSE REGULATOR receiver
WP7W18E02_00990	COG5002	protein histidine kinase activity
WP7W18E02_01000	COG2801	Transposase and inactivated derivatives
WP7W18E02_01040	COG2132	Multicopper oxidase
WP7W18E02_01060	COG3039	Transposase
WP7W18E02_01080	COG0756	dUTP diphosphatase activity
WP7W18E02_01090	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
WP7W18E02_01100	COG2003	Belongs to the UPF0758 family
WP7W18E02_01110	COG0227	Belongs to the bacterial ribosomal protein bL28 family
WP7W18E02_01120	COG0267	Belongs to the bacterial ribosomal protein bL33 family
WP7W18E02_01140	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
WP7W18E02_01150	COG2990	Protein conserved in bacteria
WP7W18E02_01160	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
WP7W18E02_01170	COG0859	PFAM glycosyl transferase family 9
WP7W18E02_01180	COG0463	Glycosyl transferase, family 2
WP7W18E02_01190	COG0859	PFAM glycosyl transferase family 9
WP7W18E02_01200	COG1519	Transferase
WP7W18E02_01220	COG1561	YicC-like family, N-terminal region
WP7W18E02_01230	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
WP7W18E02_01240	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
WP7W18E02_01260	COG0789	Transcriptional regulator
WP7W18E02_01270	COG2203	Gaf domain
WP7W18E02_01270	COG3706	GGDEF domain
WP7W18E02_01270	COG4251	negative regulation of phosphorylation
WP7W18E02_01270	COG5001	Diguanylate cyclase
WP7W18E02_01280	COG3084	Protein conserved in bacteria
WP7W18E02_01300	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
WP7W18E02_01310	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
WP7W18E02_01320	COG3639	organic phosphonate transmembrane transporter activity
WP7W18E02_01330	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
WP7W18E02_01340	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
WP7W18E02_01360	COG1335	isochorismatase
WP7W18E02_01390	COG1683	Conserved Protein
WP7W18E02_01400	COG0204	Acyl-transferase
WP7W18E02_01410	COG0204	Acyl-transferase
WP7W18E02_01420	COG0606	chelatase, subunit chli
WP7W18E02_01440	COG3978	acetolactate synthase activity
WP7W18E02_01460	COG0129	dihydroxy-acid dehydratase activity
WP7W18E02_01490	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
WP7W18E02_01500	COG0254	rRNA binding
WP7W18E02_01510	COG0702	epimerase
WP7W18E02_01520	COG0281	malic enzyme
WP7W18E02_01540	COG2205	protein histidine kinase activity
WP7W18E02_01550	COG0745	RESPONSE REGULATOR receiver
WP7W18E02_01560	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
WP7W18E02_01590	COG0366	Alpha amylase catalytic
WP7W18E02_01620	COG0443	Heat shock 70 kDa protein
WP7W18E02_01630	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
WP7W18E02_01640	COG3045	CreA protein
WP7W18E02_01680	COG0174	glutamine synthetase
WP7W18E02_01720	COG3842	ATPase activity
WP7W18E02_01730	COG1176	ABC-type spermidine putrescine transport system, permease component I
WP7W18E02_01740	COG1177	transmembrane transport
WP7W18E02_01750	COG2258	MOSC domain
WP7W18E02_01780	COG2050	protein possibly involved in aromatic compounds catabolism
WP7W18E02_01790	COG0514	ATP-dependent DNA helicase (RecQ)
WP7W18E02_01800	COG0514	ATP-dependent DNA helicase (RecQ)
WP7W18E02_01820	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
WP7W18E02_01840	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
WP7W18E02_01850	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
WP7W18E02_01860	COG2239	Acts as a magnesium transporter
WP7W18E02_01870	COG1648	precorrin-2 dehydrogenase activity
WP7W18E02_01870	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
WP7W18E02_01880	COG2116	formate transmembrane transporter activity
WP7W18E02_01910	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
WP7W18E02_01920	COG0842	Transport permease protein
WP7W18E02_01930	COG0842	Transport permease protein
WP7W18E02_01940	COG1131	(ABC) transporter
WP7W18E02_01950	COG1131	(ABC) transporter
WP7W18E02_01960	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
WP7W18E02_02010	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
WP7W18E02_02020	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
WP7W18E02_02040	COG0018	arginyl-trna synthetase
WP7W18E02_02060	COG1595	DNA-templated transcription, initiation
WP7W18E02_02070	COG3806	Anti-sigma factor
WP7W18E02_02080	COG1968	undecaprenyl-diphosphatase activity
WP7W18E02_02090	COG0667	Aldo Keto reductase
WP7W18E02_02100	COG2017	converts alpha-aldose to the beta-anomer
WP7W18E02_02110	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
WP7W18E02_02130	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
WP7W18E02_02140	COG1609	Transcriptional regulator
WP7W18E02_02150	COG3250	beta-galactosidase activity
WP7W18E02_02170	COG1129	ABC transporter
WP7W18E02_02180	COG4211	Belongs to the binding-protein-dependent transport system permease family
WP7W18E02_02230	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
WP7W18E02_02240	COG1288	antiporter activity
WP7W18E02_02250	COG1438	arginine binding
WP7W18E02_02260	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
WP7W18E02_02270	COG0540	Belongs to the ATCase OTCase family
WP7W18E02_02290	COG0688	phosphatidylethanolamine metabolic process
WP7W18E02_02320	COG3040	lipid binding
WP7W18E02_02330	COG2207	Transcriptional regulator
WP7W18E02_02340	COG1979	alcohol dehydrogenase
WP7W18E02_02350	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
WP7W18E02_02360	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
WP7W18E02_02370	COG3681	Belongs to the UPF0597 family
WP7W18E02_02390	COG0446	pyridine nucleotide-disulphide oxidoreductase
WP7W18E02_02400	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
WP7W18E02_02410	COG0564	pseudouridine synthase activity
WP7W18E02_02430	COG0542	response to heat
WP7W18E02_02440	COG2502	aspartate--ammonia ligase
WP7W18E02_02450	COG1522	sequence-specific DNA binding
WP7W18E02_02470	COG5413	integral membrane protein
WP7W18E02_02480	COG0517	IMP dehydrogenase activity
WP7W18E02_02480	COG0516	GMP reductase activity
WP7W18E02_02520	COG2205	protein histidine kinase activity
WP7W18E02_02540	COG2204	response regulator
WP7W18E02_02570	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
WP7W18E02_02580	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
WP7W18E02_02610	COG0745	RESPONSE REGULATOR receiver
WP7W18E02_02620	COG2205	protein histidine kinase activity
WP7W18E02_02640	COG0243	molybdopterin cofactor binding
WP7W18E02_02650	COG3005	denitrification pathway
WP7W18E02_02660	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
WP7W18E02_02670	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
WP7W18E02_02680	COG0569	domain protein
WP7W18E02_02690	COG0812	UDP-N-acetylmuramate dehydrogenase activity
WP7W18E02_02720	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
WP7W18E02_02740	COG0250	Participates in transcription elongation, termination and antitermination
WP7W18E02_02750	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
WP7W18E02_02760	COG0081	regulation of translation
WP7W18E02_02770	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
WP7W18E02_02780	COG0222	ribosome binding
WP7W18E02_02790	COG0085	RNA polymerase activity
WP7W18E02_02800	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
WP7W18E02_02810	COG2964	Protein conserved in bacteria
WP7W18E02_02850	COG2168	tRNA wobble position uridine thiolation
WP7W18E02_02860	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
WP7W18E02_02870	COG0049	tRNA binding
WP7W18E02_02880	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
WP7W18E02_02890	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
WP7W18E02_02900	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
WP7W18E02_02930	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
WP7W18E02_02930	COG0475	glutathione-regulated potassium exporter activity
WP7W18E02_02940	COG2249	NAD(P)H dehydrogenase (quinone) activity
WP7W18E02_02970	COG1770	oligopeptidase
WP7W18E02_03010	COG3714	YhhN family
WP7W18E02_03060	COG1301	dicarboxylic acid transport
WP7W18E02_03080	COG2095	MarC family integral membrane protein
WP7W18E02_03100	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
WP7W18E02_03120	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
WP7W18E02_03140	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
WP7W18E02_03190	COG0742	ribosomal rna small subunit methyltransferase
WP7W18E02_03200	COG0552	protein localization to endoplasmic reticulum
WP7W18E02_03210	COG2884	Cell division ATP-binding protein ftsE
WP7W18E02_03220	COG2177	Part of the ABC transporter FtsEX involved in
WP7W18E02_03240	COG0288	reversible hydration of carbon dioxide
WP7W18E02_03250	COG2188	Transcriptional regulator
WP7W18E02_03260	COG1228	amidohydrolase
WP7W18E02_03270	COG0010	Belongs to the arginase family
WP7W18E02_03280	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
WP7W18E02_03290	COG2986	histidine ammonia-lyase
WP7W18E02_03300	COG0387	Pfam Sodium calcium exchanger
WP7W18E02_03310	COG2200	EAL domain
WP7W18E02_03320	COG2200	EAL domain
WP7W18E02_03320	COG2199	diguanylate cyclase activity
WP7W18E02_03430	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
WP7W18E02_03440	COG1459	type II secretion system
WP7W18E02_03520	COG1077	Cell shape determining protein MreB Mrl
WP7W18E02_03530	COG1792	Involved in formation and maintenance of cell shape
WP7W18E02_03540	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
WP7W18E02_03550	COG0424	maF-like protein
WP7W18E02_03560	COG1530	ribonuclease E activity
WP7W18E02_03570	COG3164	Protein of unknown function
WP7W18E02_03580	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
WP7W18E02_03590	COG0312	modulator of DNA gyrase
WP7W18E02_03620	COG0477	Major facilitator Superfamily
WP7W18E02_03640	COG2321	neutral zinc metallopeptidase
WP7W18E02_03700	COG0189	ligase activity
WP7W18E02_03710	COG0642	Histidine kinase
WP7W18E02_03720	COG0745	RESPONSE REGULATOR receiver
WP7W18E02_03750	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
WP7W18E02_03760	COG0352	thiamine-phosphate diphosphorylase activity
WP7W18E02_03770	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
WP7W18E02_03790	COG2022	thiamine diphosphate biosynthetic process
WP7W18E02_03800	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
WP7W18E02_03810	COG0583	DNA-binding transcription factor activity
WP7W18E02_03830	COG3039	Transposase
WP7W18E02_03880	COG3706	GGDEF domain
WP7W18E02_03890	COG3932	Exopolysaccharide synthesis, ExoD
WP7W18E02_03920	COG1733	regulation of RNA biosynthetic process
WP7W18E02_03960	COG1247	-acetyltransferase
WP7W18E02_03980	COG1494	fructose-1,6-bisphosphatase
WP7W18E02_04000	COG3071	HemY protein
WP7W18E02_04010	COG2959	enzyme of heme biosynthesis
WP7W18E02_04030	COG0181	hydroxymethylbilane synthase activity
WP7W18E02_04040	COG3072	Adenylate cyclase
WP7W18E02_04050	COG0400	carboxylic ester hydrolase activity
WP7W18E02_04060	COG1965	Belongs to the frataxin family
WP7W18E02_04080	COG0019	diaminopimelate decarboxylase activity
WP7W18E02_04090	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
WP7W18E02_04120	COG1011	Hydrolase
WP7W18E02_04140	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
WP7W18E02_04150	COG0561	phosphatase activity
WP7W18E02_04170	COG1988	membrane-bound metal-dependent
WP7W18E02_04180	COG1058	Belongs to the CinA family
WP7W18E02_04180	COG1546	Belongs to the CinA family
WP7W18E02_04200	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
WP7W18E02_04220	COG1522	sequence-specific DNA binding
WP7W18E02_04240	COG3135	benzoate transporter
WP7W18E02_04250	COG1396	sequence-specific DNA binding
WP7W18E02_04280	COG2926	Belongs to the UPF0265 family
WP7W18E02_04300	COG3028	Belongs to the UPF0307 family
WP7W18E02_04310	COG0312	modulator of DNA gyrase
WP7W18E02_04320	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
WP7W18E02_04330	COG5007	Belongs to the BolA IbaG family
WP7W18E02_04350	COG2854	intermembrane phospholipid transfer
WP7W18E02_04360	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
WP7W18E02_04370	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
WP7W18E02_04380	COG1127	ABC transporter
WP7W18E02_04390	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
WP7W18E02_04390	COG0517	IMP dehydrogenase activity
WP7W18E02_04400	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
WP7W18E02_04410	COG3117	lipopolysaccharide transmembrane transporter activity
WP7W18E02_04420	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
WP7W18E02_04430	COG1137	ATPase activity
WP7W18E02_04460	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
WP7W18E02_04470	COG1660	Displays ATPase and GTPase activities
WP7W18E02_04480	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
WP7W18E02_04520	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
WP7W18E02_04530	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
WP7W18E02_04550	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
WP7W18E02_04560	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
WP7W18E02_04570	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
WP7W18E02_04580	COG0723	plastoquinol--plastocyanin reductase activity
WP7W18E02_04590	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
WP7W18E02_04600	COG2857	Cytochrome c1
WP7W18E02_04610	COG0625	glutathione transferase activity
WP7W18E02_04620	COG2969	positive regulation of protein catabolic process
WP7W18E02_04630	COG2823	Periplasmic or secreted lipoprotein
WP7W18E02_04640	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
WP7W18E02_04650	COG0792	nuclease activity
WP7W18E02_04660	COG3107	peptidoglycan biosynthetic process
WP7W18E02_04670	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
WP7W18E02_04680	COG2001	Belongs to the MraZ family
WP7W18E02_04690	COG0275	rRNA processing
WP7W18E02_04700	COG3116	cell division
WP7W18E02_04710	COG0768	penicillin binding
WP7W18E02_04720	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
WP7W18E02_04730	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
WP7W18E02_04740	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
WP7W18E02_04750	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
WP7W18E02_04760	COG0772	Belongs to the SEDS family
WP7W18E02_04770	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
WP7W18E02_04780	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
WP7W18E02_04790	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
WP7W18E02_04800	COG0849	cell division
WP7W18E02_04810	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
WP7W18E02_04820	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
WP7W18E02_04840	COG0653	protein targeting
WP7W18E02_04860	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
WP7W18E02_04870	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
WP7W18E02_04890	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
WP7W18E02_04900	COG1459	type II secretion system
WP7W18E02_04910	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
WP7W18E02_04950	COG2186	Transcriptional regulator
WP7W18E02_04960	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
WP7W18E02_04970	COG0508	dehydrogenase complex catalyzes the overall conversion of
WP7W18E02_04980	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
WP7W18E02_04990	COG3706	GGDEF domain
WP7W18E02_05020	COG0840	transmembrane signaling receptor activity
WP7W18E02_05030	COG1752	Esterase of the alpha-beta hydrolase superfamily
WP7W18E02_05040	COG1049	propionate catabolic process, 2-methylcitrate cycle
WP7W18E02_05050	COG2200	EAL domain
WP7W18E02_05070	COG1280	lysine exporter protein (LysE YggA)
WP7W18E02_05090	COG0523	cobalamin synthesis protein
WP7W18E02_05100	COG0477	Major facilitator Superfamily
WP7W18E02_05130	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
WP7W18E02_05140	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
WP7W18E02_05200	COG5006	permease, DMT superfamily
WP7W18E02_05210	COG1522	sequence-specific DNA binding
WP7W18E02_05220	COG0110	maltose O-acetyltransferase activity
WP7W18E02_05230	COG0366	Alpha amylase catalytic
WP7W18E02_05240	COG1263	PTS System
WP7W18E02_05240	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
WP7W18E02_05270	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
WP7W18E02_05280	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
WP7W18E02_05290	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
WP7W18E02_05290	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
WP7W18E02_05300	COG2723	6-phospho-beta-galactosidase activity
WP7W18E02_05310	COG1447	Phosphotransferase system cellobiose-specific component IIA
WP7W18E02_05320	COG1940	carbohydrate kinase activity
WP7W18E02_05360	COG1609	Transcriptional regulator
WP7W18E02_05380	COG0252	asparaginase activity
WP7W18E02_05410	COG1803	Methylglyoxal synthase
WP7W18E02_05450	COG1444	tRNA N-acetyltransferase activity
WP7W18E02_05460	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
WP7W18E02_05480	COG3706	GGDEF domain
WP7W18E02_05490	COG0557	exoribonuclease II activity
WP7W18E02_05500	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
WP7W18E02_05520	COG2153	protein acetylation
WP7W18E02_05550	COG1914	H( )-stimulated, divalent metal cation uptake system
WP7W18E02_05560	COG0360	Binds together with S18 to 16S ribosomal RNA
WP7W18E02_05570	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
WP7W18E02_05580	COG0359	binds to the 23S rRNA
WP7W18E02_05650	COG1064	alcohol dehydrogenase
WP7W18E02_05660	COG1238	metal cluster binding
WP7W18E02_05670	COG0612	Peptidase, M16
WP7W18E02_05680	COG2918	glutathione biosynthetic process
WP7W18E02_05690	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
WP7W18E02_05700	COG1027	Aspartate ammonia-lyase
WP7W18E02_05710	COG3030	protein affecting phage T7 exclusion by the F plasmid
WP7W18E02_05720	COG0534	Mate efflux family protein
WP7W18E02_05730	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
WP7W18E02_05740	COG0459	protein refolding
WP7W18E02_05770	COG0564	pseudouridine synthase activity
WP7W18E02_05780	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
WP7W18E02_05790	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
WP7W18E02_05810	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
WP7W18E02_05820	COG4208	sulfate ABC transporter
WP7W18E02_05830	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
WP7W18E02_05840	COG0583	DNA-binding transcription factor activity
WP7W18E02_05860	COG3397	chitin binding
WP7W18E02_05870	COG0840	transmembrane signaling receptor activity
WP7W18E02_05920	COG1328	CTP reductase activity
WP7W18E02_05930	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
WP7W18E02_05960	COG1448	Aminotransferase
WP7W18E02_05970	COG2194	sulfuric ester hydrolase activity
WP7W18E02_06010	COG1215	transferase activity, transferring glycosyl groups
WP7W18E02_06030	COG3118	belongs to the thioredoxin family
WP7W18E02_06030	COG0457	Tetratricopeptide repeat
WP7W18E02_06120	COG0513	Belongs to the DEAD box helicase family
WP7W18E02_06160	COG0840	transmembrane signaling receptor activity
WP7W18E02_06180	COG4166	transmembrane transport
WP7W18E02_06200	COG0110	maltose O-acetyltransferase activity
WP7W18E02_06220	COG1024	Enoyl-CoA hydratase
WP7W18E02_06250	COG4221	oxidoreductase activity
WP7W18E02_06260	COG0442	prolyl-tRNA aminoacylation
WP7W18E02_06270	COG0632	four-way junction helicase activity
WP7W18E02_06280	COG2255	four-way junction helicase activity
WP7W18E02_06290	COG1271	oxidase subunit
WP7W18E02_06300	COG1294	oxidase, subunit
WP7W18E02_06310	COG4890	Cyd operon protein YbgT
WP7W18E02_06320	COG3790	cyd operon protein YbgE
WP7W18E02_06330	COG0824	Thioesterase
WP7W18E02_06340	COG0811	peptide transport
WP7W18E02_06370	COG0823	Involved in the tonB-independent uptake of proteins
WP7W18E02_06380	COG2885	chlorophyll binding
WP7W18E02_06390	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
WP7W18E02_06400	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
WP7W18E02_06420	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
WP7W18E02_06430	COG1640	4-alpha-glucanotransferase
WP7W18E02_06440	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
WP7W18E02_06490	COG2130	NADP-dependent
WP7W18E02_06500	COG1846	Transcriptional regulator
WP7W18E02_06560	COG0561	phosphatase activity
WP7W18E02_06590	COG0733	neurotransmitter:sodium symporter activity
WP7W18E02_06600	COG0733	neurotransmitter:sodium symporter activity
WP7W18E02_06630	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
WP7W18E02_06660	COG1794	racemase activity, acting on amino acids and derivatives
WP7W18E02_06680	COG1022	Amp-dependent synthetase and ligase
WP7W18E02_06720	COG0456	acetyltransferase
WP7W18E02_06750	COG2425	protein containing a von Willebrand factor type A (vWA) domain
WP7W18E02_06760	COG3300	MHYT domain
WP7W18E02_06760	COG5001	Diguanylate cyclase
WP7W18E02_06780	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
WP7W18E02_06810	COG1902	pentaerythritol trinitrate reductase activity
WP7W18E02_06840	COG2852	Protein conserved in bacteria
WP7W18E02_06860	COG2957	Belongs to the agmatine deiminase family
WP7W18E02_06870	COG0154	amidase activity
WP7W18E02_06930	COG0513	Belongs to the DEAD box helicase family
WP7W18E02_06940	COG3706	GGDEF domain
WP7W18E02_06960	COG1912	Pfam S-adenosyl-l-methionine hydroxide adenosyltransferase
WP7W18E02_06980	COG1136	(ABC) transporter
WP7W18E02_06980	COG0577	efflux transmembrane transporter activity
WP7W18E02_06990	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
WP7W18E02_07000	COG0745	RESPONSE REGULATOR receiver
WP7W18E02_07010	COG2205	protein histidine kinase activity
WP7W18E02_07090	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
WP7W18E02_07100	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
WP7W18E02_07120	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
WP7W18E02_07180	COG0745	RESPONSE REGULATOR receiver
WP7W18E02_07190	COG3104	oligopeptide transport
WP7W18E02_07200	COG1210	Utp--glucose-1-phosphate uridylyltransferase
WP7W18E02_07210	COG1555	photosystem II stabilization
WP7W18E02_07230	COG2350	Protein conserved in bacteria
WP7W18E02_07240	COG2917	probably involved in intracellular septation
WP7W18E02_07250	COG0076	glutamate decarboxylase activity
WP7W18E02_07260	COG1272	protein, Hemolysin III
WP7W18E02_07270	COG0569	domain protein
WP7W18E02_07270	COG2985	domain, Protein
WP7W18E02_07310	COG0477	Major facilitator Superfamily
WP7W18E02_07320	COG0583	DNA-binding transcription factor activity
WP7W18E02_07340	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
WP7W18E02_07350	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
WP7W18E02_07370	COG2731	YhcH YjgK YiaL family protein
WP7W18E02_07390	COG0668	transmembrane transport
WP7W18E02_07400	COG1376	ErfK ybiS ycfS ynhG family protein
WP7W18E02_07410	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
WP7W18E02_07420	COG3385	transposase activity
WP7W18E02_07450	COG0789	Transcriptional regulator
WP7W18E02_07460	COG3039	Transposase
WP7W18E02_07500	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
WP7W18E02_07520	COG0488	(ABC) transporter
WP7W18E02_07530	COG0517	IMP dehydrogenase activity
WP7W18E02_07540	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
WP7W18E02_07550	COG0835	chemotaxis
WP7W18E02_07550	COG0784	Response regulator, receiver
WP7W18E02_07560	COG2755	lipolytic protein G-D-S-L family
WP7W18E02_07570	COG4181	ATPase activity
WP7W18E02_07580	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
WP7W18E02_07590	COG1090	epimerase
WP7W18E02_07600	COG2200	EAL domain
WP7W18E02_07610	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
WP7W18E02_07620	COG4935	Belongs to the peptidase S8 family
WP7W18E02_07620	COG2234	aminopeptidase activity
WP7W18E02_07630	COG0220	tRNA (guanine-N7-)-methyltransferase activity
WP7W18E02_07640	COG3171	Protein conserved in bacteria
WP7W18E02_07650	COG2066	Belongs to the glutaminase family
WP7W18E02_07660	COG2897	thiosulfate sulfurtransferase activity
WP7W18E02_07680	COG1132	(ABC) transporter
WP7W18E02_07710	COG2211	Major facilitator Superfamily
WP7W18E02_07730	COG1609	Transcriptional regulator
WP7W18E02_07750	COG2017	converts alpha-aldose to the beta-anomer
WP7W18E02_07760	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
WP7W18E02_07780	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
WP7W18E02_07800	COG3076	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome
WP7W18E02_07810	COG5001	Diguanylate cyclase
WP7W18E02_07810	COG3300	MHYT domain
WP7W18E02_07830	COG2207	Transcriptional regulator
WP7W18E02_07840	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
WP7W18E02_07870	COG4628	conserved protein (DUF2132)
WP7W18E02_07880	COG0688	phosphatidylethanolamine metabolic process
WP7W18E02_07900	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
WP7W18E02_07910	COG1278	Cold shock
WP7W18E02_07930	COG0840	transmembrane signaling receptor activity
WP7W18E02_07940	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
WP7W18E02_07980	COG0848	biopolymer transport protein
WP7W18E02_07990	COG0811	peptide transport
WP7W18E02_08000	COG0811	peptide transport
WP7W18E02_08020	COG4206	TonB-dependent receptor
WP7W18E02_08040	COG2801	Transposase and inactivated derivatives
WP7W18E02_08050	COG4174	ABC transporter (Permease)
WP7W18E02_08060	COG4239	(ABC) transporter, permease
WP7W18E02_08070	COG0747	negative chemotaxis
WP7W18E02_08080	COG0444	Belongs to the ABC transporter superfamily
WP7W18E02_08090	COG4608	Belongs to the ABC transporter superfamily
WP7W18E02_08110	COG2195	Cleaves the N-terminal amino acid of tripeptides
WP7W18E02_08430	COG4695	Portal protein
WP7W18E02_08600	COG4974	Belongs to the 'phage' integrase family
WP7W18E02_08610	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
WP7W18E02_08650	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
WP7W18E02_08700	COG0243	molybdopterin cofactor binding
WP7W18E02_08730	COG1116	anion transmembrane transporter activity
WP7W18E02_08730	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
WP7W18E02_08740	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
WP7W18E02_08750	COG1116	anion transmembrane transporter activity
WP7W18E02_08760	COG2146	nitrite reductase [NAD(P)H] activity
WP7W18E02_08760	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
WP7W18E02_08770	COG2146	nitrite reductase [NAD(P)H] activity
WP7W18E02_08770	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
WP7W18E02_08780	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
WP7W18E02_08790	COG2313	pseudouridylate synthase activity
WP7W18E02_08860	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
WP7W18E02_08870	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
WP7W18E02_08890	COG0318	PFAM AMP-dependent synthetase and ligase
WP7W18E02_08920	COG2986	histidine ammonia-lyase
WP7W18E02_08970	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
WP7W18E02_08990	COG1028	Short-chain dehydrogenase reductase Sdr
WP7W18E02_09000	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
WP7W18E02_09020	COG0521	Mo-molybdopterin cofactor biosynthetic process
WP7W18E02_09040	COG2966	Psort location CytoplasmicMembrane, score
WP7W18E02_09050	COG3610	response to peptide
WP7W18E02_09070	COG4175	Glycine betaine
WP7W18E02_09080	COG4176	ABC-type proline glycine betaine transport system permease component
WP7W18E02_09090	COG2113	Glycine betaine
WP7W18E02_09100	COG0175	sulfate reduction
WP7W18E02_09110	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
WP7W18E02_09120	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
WP7W18E02_09130	COG0384	phenazine biosynthesis protein PhzF
WP7W18E02_09140	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
WP7W18E02_09150	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
WP7W18E02_09170	COG5001	Diguanylate cyclase
WP7W18E02_09180	COG0786	glutamate:sodium symporter activity
WP7W18E02_09190	COG0252	asparaginase activity
WP7W18E02_09200	COG3139	Protein of unknown function (DUF1315)
WP7W18E02_09240	COG0616	signal peptide processing
WP7W18E02_09250	COG1902	pentaerythritol trinitrate reductase activity
WP7W18E02_09250	COG0446	pyridine nucleotide-disulphide oxidoreductase
WP7W18E02_09260	COG0778	Nitroreductase
WP7W18E02_09280	COG2264	protein methyltransferase activity
WP7W18E02_09290	COG0604	alcohol dehydrogenase
WP7W18E02_09300	COG0583	DNA-binding transcription factor activity
WP7W18E02_09310	COG2190	(PTS) system
WP7W18E02_09310	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
WP7W18E02_09310	COG1263	PTS System
WP7W18E02_09320	COG4145	pantothenate transmembrane transporter activity
WP7W18E02_09340	COG3924	membrane
WP7W18E02_09390	COG0697	spore germination
WP7W18E02_09530	COG0840	transmembrane signaling receptor activity
WP7W18E02_09580	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
WP7W18E02_09640	COG0439	Biotin carboxylase
WP7W18E02_09650	COG0511	ligase activity, forming carbon-carbon bonds
WP7W18E02_09660	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
WP7W18E02_09680	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
WP7W18E02_09710	COG3381	protein complex oligomerization
WP7W18E02_09730	COG3005	denitrification pathway
WP7W18E02_09740	COG0745	RESPONSE REGULATOR receiver
WP7W18E02_09760	COG1879	ABC-type sugar transport system periplasmic component
WP7W18E02_09770	COG2205	protein histidine kinase activity
WP7W18E02_09770	COG2198	Histidine kinase
WP7W18E02_09770	COG0784	Response regulator, receiver
WP7W18E02_09790	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
WP7W18E02_09810	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
WP7W18E02_09820	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
WP7W18E02_09820	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
WP7W18E02_09850	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
WP7W18E02_09860	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
WP7W18E02_09870	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
WP7W18E02_09880	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
WP7W18E02_09890	COG4172	Belongs to the ABC transporter superfamily
WP7W18E02_09930	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
WP7W18E02_09940	COG0142	geranyltranstransferase activity
WP7W18E02_09950	COG1722	exodeoxyribonuclease VII activity
WP7W18E02_09960	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
WP7W18E02_09970	COG1360	Flagellar Motor Protein
WP7W18E02_10000	COG1534	Rna-binding protein
WP7W18E02_10010	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
WP7W18E02_10030	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
WP7W18E02_10040	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
WP7W18E02_10050	COG0149	triose-phosphate isomerase activity
WP7W18E02_10060	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
WP7W18E02_10070	COG0779	Required for maturation of 30S ribosomal subunits
WP7W18E02_10080	COG0195	Participates in both transcription termination and antitermination
WP7W18E02_10090	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
WP7W18E02_10100	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
WP7W18E02_10110	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
WP7W18E02_10120	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
WP7W18E02_10130	COG1185	polyribonucleotide nucleotidyltransferase activity
WP7W18E02_10140	COG2211	Major facilitator Superfamily
WP7W18E02_10150	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
WP7W18E02_10170	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
WP7W18E02_10210	COG0312	modulator of DNA gyrase
WP7W18E02_10240	COG4974	Belongs to the 'phage' integrase family
WP7W18E02_10260	COG1970	mechanosensitive ion channel activity
WP7W18E02_10310	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
WP7W18E02_10330	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
WP7W18E02_10350	COG0321	lipoyl(octanoyl) transferase activity
WP7W18E02_10360	COG2921	Belongs to the UPF0250 family
WP7W18E02_10370	COG1686	Belongs to the peptidase S11 family
WP7W18E02_10380	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
WP7W18E02_10390	COG2951	lytic endotransglycosylase activity
WP7W18E02_10400	COG0772	Belongs to the SEDS family
WP7W18E02_10410	COG0768	penicillin binding
WP7W18E02_10420	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
WP7W18E02_10430	COG0799	negative regulation of ribosome biogenesis
WP7W18E02_10440	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
WP7W18E02_10470	COG0495	leucyl-tRNA aminoacylation
WP7W18E02_10480	COG2888	peptidyl-tyrosine sulfation
WP7W18E02_10490	COG0815	Transfers the fatty acyl group on membrane lipoproteins
WP7W18E02_10500	COG4535	Mg2 and Co2 transporter CorC
WP7W18E02_10510	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
WP7W18E02_10520	COG1702	phosphate starvation-inducible protein PhoH
WP7W18E02_10530	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
WP7W18E02_10540	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
WP7W18E02_10550	COG1278	Cold shock
WP7W18E02_10560	COG0583	DNA-binding transcription factor activity
WP7W18E02_10580	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
WP7W18E02_10610	COG3706	GGDEF domain
WP7W18E02_10630	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
WP7W18E02_10650	COG3647	Membrane
WP7W18E02_10660	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
WP7W18E02_10680	COG0516	GMP reductase activity
WP7W18E02_10710	COG0745	RESPONSE REGULATOR receiver
WP7W18E02_10730	COG0300	oxidoreductase activity
WP7W18E02_10770	COG4106	trans-aconitate 2-methyltransferase activity
WP7W18E02_10780	COG3214	Protein conserved in bacteria
WP7W18E02_10800	COG3029	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
WP7W18E02_10810	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
WP7W18E02_10820	COG1053	succinate dehydrogenase
WP7W18E02_10840	COG0584	glycerophosphoryl diester phosphodiesterase
WP7W18E02_10850	COG1511	domain protein
WP7W18E02_10850	COG3264	Mechanosensitive ion channel
WP7W18E02_10870	COG0739	heme binding
WP7W18E02_10900	COG0583	DNA-binding transcription factor activity
WP7W18E02_10930	COG0583	DNA-binding transcription factor activity
WP7W18E02_10940	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
WP7W18E02_11000	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
WP7W18E02_11010	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
WP7W18E02_11030	COG0338	D12 class N6 adenine-specific DNA methyltransferase
WP7W18E02_11040	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
WP7W18E02_11060	COG0180	Tryptophanyl-tRNA synthetase
WP7W18E02_11090	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
WP7W18E02_11110	COG1012	belongs to the aldehyde dehydrogenase family
WP7W18E02_11140	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
WP7W18E02_11200	COG0490	domain, Protein
WP7W18E02_11200	COG0471	metal ion transport
WP7W18E02_11210	COG0012	GTP binding
WP7W18E02_11220	COG0193	aminoacyl-tRNA hydrolase activity
WP7W18E02_11230	COG0737	Belongs to the 5'-nucleotidase family
WP7W18E02_11240	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
WP7W18E02_11250	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
WP7W18E02_11260	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
WP7W18E02_11270	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
WP7W18E02_11280	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
WP7W18E02_11290	COG2890	protein-(glutamine-N5) methyltransferase activity
WP7W18E02_11310	COG2912	Transglutaminase-like superfamily
WP7W18E02_11330	COG1301	dicarboxylic acid transport
WP7W18E02_11350	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
WP7W18E02_11380	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
WP7W18E02_11390	COG1115	amino acid carrier protein
WP7W18E02_11430	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
WP7W18E02_11450	COG0189	ligase activity
WP7W18E02_11460	COG1385	rRNA (uridine-N3-)-methyltransferase activity
WP7W18E02_11480	COG3091	SprT-like family
WP7W18E02_11500	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
WP7W18E02_11530	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
WP7W18E02_11550	COG0739	heme binding
WP7W18E02_11560	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
WP7W18E02_11570	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
WP7W18E02_11570	COG3408	Glycogen debranching enzyme
WP7W18E02_11600	COG0583	DNA-binding transcription factor activity
WP7W18E02_11620	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
WP7W18E02_11640	COG0583	DNA-binding transcription factor activity
WP7W18E02_11650	COG1028	Short-chain dehydrogenase reductase Sdr
WP7W18E02_11660	COG0616	signal peptide processing
WP7W18E02_11670	COG3724	N-succinylarginine dihydrolase activity
WP7W18E02_11710	COG0840	transmembrane signaling receptor activity
WP7W18E02_11730	COG2971	BadF BadG BcrA BcrD
WP7W18E02_11750	COG4608	Belongs to the ABC transporter superfamily
WP7W18E02_11760	COG0444	Belongs to the ABC transporter superfamily
WP7W18E02_11770	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
WP7W18E02_11800	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
WP7W18E02_11810	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
WP7W18E02_11810	COG1073	alpha beta
WP7W18E02_11810	COG3064	Membrane
WP7W18E02_11830	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
WP7W18E02_11870	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
WP7W18E02_11980	COG1684	flagellar biosynthetic protein fliR
WP7W18E02_12000	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
WP7W18E02_12050	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
WP7W18E02_12060	COG0643	Histidine kinase
WP7W18E02_12060	COG0784	Response regulator, receiver
WP7W18E02_12060	COG2198	Histidine kinase
WP7W18E02_12070	COG2201	protein-glutamate methylesterase activity
WP7W18E02_12080	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
WP7W18E02_12090	COG1360	Flagellar Motor Protein
WP7W18E02_12100	COG1192	Involved in chromosome partitioning
WP7W18E02_12120	COG0835	chemotaxis
WP7W18E02_12150	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
WP7W18E02_12160	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
WP7W18E02_12170	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
WP7W18E02_12180	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
WP7W18E02_12190	COG1138	Cytochrome C-type biogenesis protein
WP7W18E02_12200	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
WP7W18E02_12210	COG3088	subunit of a heme lyase
WP7W18E02_12210	COG4235	cytochrome complex assembly
WP7W18E02_12250	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
WP7W18E02_12260	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
WP7W18E02_12260	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
WP7W18E02_12290	COG0259	pyridoxamine-phosphate oxidase activity
WP7W18E02_12310	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
WP7W18E02_12320	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
WP7W18E02_12340	COG0083	homoserine kinase activity
WP7W18E02_12350	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
WP7W18E02_12360	COG4319	ketosteroid isomerase
WP7W18E02_12380	COG2801	Transposase and inactivated derivatives
WP7W18E02_12390	COG2801	Transposase and inactivated derivatives
WP7W18E02_12410	COG2801	Transposase and inactivated derivatives
WP7W18E02_12530	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
WP7W18E02_12540	COG1763	Mo-molybdopterin cofactor biosynthetic process
WP7W18E02_12550	COG0746	molybdenum cofactor guanylyltransferase activity
WP7W18E02_12560	COG0281	malic enzyme
WP7W18E02_12630	COG1129	ABC transporter
WP7W18E02_12640	COG1172	Belongs to the binding-protein-dependent transport system permease family
WP7W18E02_12650	COG1472	Belongs to the glycosyl hydrolase 3 family
WP7W18E02_12680	COG3264	Mechanosensitive ion channel
WP7W18E02_12680	COG1196	nuclear chromosome segregation
WP7W18E02_12690	COG0469	pyruvate kinase activity
WP7W18E02_12700	COG2850	peptidyl-arginine hydroxylation
WP7W18E02_12710	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
WP7W18E02_12720	COG2915	High frequency lysogenization protein hflD homolog
WP7W18E02_12730	COG0482	sulfurtransferase activity
WP7W18E02_12770	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
WP7W18E02_12800	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
WP7W18E02_12800	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
WP7W18E02_12800	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
WP7W18E02_12870	COG5492	domain, Protein
WP7W18E02_12870	COG4932	domain protein
WP7W18E02_12880	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
WP7W18E02_12920	COG2207	Transcriptional regulator
WP7W18E02_12930	COG0538	isocitrate dehydrogenase activity
WP7W18E02_12950	COG3048	D-serine ammonia-lyase activity
WP7W18E02_12960	COG2610	gluconate transmembrane transporter activity
WP7W18E02_12970	COG0583	DNA-binding transcription factor activity
WP7W18E02_12980	COG2916	Histone family protein nucleoid-structuring protein H-NS
WP7W18E02_12990	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
WP7W18E02_13000	COG2375	cellular response to nickel ion
WP7W18E02_13020	COG0577	efflux transmembrane transporter activity
WP7W18E02_13020	COG1136	(ABC) transporter
WP7W18E02_13030	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
WP7W18E02_13050	COG1227	inorganic diphosphatase activity
WP7W18E02_13060	COG0497	DNA recombination
WP7W18E02_13070	COG3706	GGDEF domain
WP7W18E02_13080	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
WP7W18E02_13090	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
WP7W18E02_13100	COG0443	Heat shock 70 kDa protein
WP7W18E02_13110	COG0484	heat shock protein binding
WP7W18E02_13170	COG1285	pathogenesis
WP7W18E02_13250	COG1566	PFAM secretion protein HlyD family protein
WP7W18E02_13260	COG0577	efflux transmembrane transporter activity
WP7W18E02_13260	COG1136	(ABC) transporter
WP7W18E02_13270	COG1136	(ABC) transporter
WP7W18E02_13270	COG0577	efflux transmembrane transporter activity
WP7W18E02_13280	COG0577	efflux transmembrane transporter activity
WP7W18E02_13280	COG1136	(ABC) transporter
WP7W18E02_13300	COG0095	Lipoate-protein ligase
WP7W18E02_13330	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
WP7W18E02_13340	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
WP7W18E02_13360	COG0708	Exodeoxyribonuclease III
WP7W18E02_13390	COG0071	Belongs to the small heat shock protein (HSP20) family
WP7W18E02_13460	COG0583	DNA-binding transcription factor activity
WP7W18E02_13470	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
WP7W18E02_13480	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
WP7W18E02_13490	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
WP7W18E02_13500	COG1845	cytochrome c oxidase, subunit III
WP7W18E02_13510	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
WP7W18E02_13520	COG0109	protoheme IX farnesyltransferase activity
WP7W18E02_13530	COG2814	Major facilitator Superfamily
WP7W18E02_13540	COG5507	3-demethylubiquinone-9 3-methyltransferase
WP7W18E02_13600	COG3550	peptidyl-serine autophosphorylation
WP7W18E02_13610	COG1396	sequence-specific DNA binding
WP7W18E02_13650	COG0159	tryptophan synthase activity
WP7W18E02_13660	COG0133	tryptophan synthase activity
WP7W18E02_13670	COG0135	phosphoribosylanthranilate isomerase activity
WP7W18E02_13670	COG0134	indole-3-glycerol-phosphate synthase activity
WP7W18E02_13680	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
WP7W18E02_13690	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
WP7W18E02_13690	COG0512	Glutamine amidotransferase of anthranilate synthase
WP7W18E02_13700	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
WP7W18E02_13720	COG0009	L-threonylcarbamoyladenylate synthase
WP7W18E02_13740	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
WP7W18E02_13760	COG1946	Acyl-CoA thioesterase
WP7W18E02_13790	COG1309	transcriptional regulator
WP7W18E02_13800	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
WP7W18E02_13810	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
WP7W18E02_13900	COG3039	Transposase
WP7W18E02_13920	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
WP7W18E02_13940	COG1960	acyl-CoA dehydrogenase activity
WP7W18E02_13950	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
WP7W18E02_13970	COG0469	pyruvate kinase activity
WP7W18E02_13980	COG1737	Transcriptional regulator
WP7W18E02_14000	COG2205	protein histidine kinase activity
WP7W18E02_14030	COG2801	Transposase and inactivated derivatives
WP7W18E02_14060	COG2244	polysaccharide biosynthetic process
WP7W18E02_14070	COG1216	Glycosyl transferase, family 2
WP7W18E02_14090	COG0438	transferase activity, transferring glycosyl groups
WP7W18E02_14110	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
WP7W18E02_14120	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
WP7W18E02_14140	COG0662	Cupin 2, conserved barrel domain protein
WP7W18E02_14140	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
WP7W18E02_14170	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
WP7W18E02_14180	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
WP7W18E02_14210	COG3132	Protein of unknown function, DUF480
WP7W18E02_14290	COG1278	Cold shock
WP7W18E02_14350	COG0697	spore germination
WP7W18E02_14380	COG1187	pseudouridine synthase activity
WP7W18E02_14400	COG4166	transmembrane transport
WP7W18E02_14410	COG0622	Phosphoesterase
WP7W18E02_14440	COG1261	Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly
WP7W18E02_14450	COG0784	Response regulator, receiver
WP7W18E02_14450	COG0835	chemotaxis
WP7W18E02_14460	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
WP7W18E02_14470	COG1815	bacterial-type flagellum-dependent cell motility
WP7W18E02_14500	COG1749	Flagellar hook protein flgE
WP7W18E02_14530	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
WP7W18E02_14540	COG1706	bacterial-type flagellum-dependent cell motility
WP7W18E02_14550	COG3951	Flagellar rod assembly protein muramidase FlgJ
WP7W18E02_14550	COG1705	Flagellar rod assembly protein muramidase FlgJ
WP7W18E02_14580	COG2239	Acts as a magnesium transporter
WP7W18E02_14600	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
WP7W18E02_14610	COG2716	regulation of RNA biosynthetic process
WP7W18E02_14640	COG3852	Histidine kinase
WP7W18E02_14660	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
WP7W18E02_14670	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
WP7W18E02_14680	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
WP7W18E02_14690	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
WP7W18E02_14730	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
WP7W18E02_14770	COG0573	inorganic phosphate transmembrane transporter activity
WP7W18E02_14780	COG0581	inorganic phosphate transmembrane transporter activity
WP7W18E02_14810	COG1253	flavin adenine dinucleotide binding
WP7W18E02_14820	COG1253	flavin adenine dinucleotide binding
WP7W18E02_14850	COG0531	amino acid
WP7W18E02_14870	COG1126	abc transporter atp-binding protein
WP7W18E02_14890	COG0765	amino acid transport
WP7W18E02_14900	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
WP7W18E02_14920	COG2271	Major facilitator Superfamily
WP7W18E02_14940	COG2197	response regulator
WP7W18E02_14950	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
WP7W18E02_14990	COG1785	Belongs to the alkaline phosphatase family
WP7W18E02_15000	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
WP7W18E02_15010	COG0477	Major facilitator Superfamily
WP7W18E02_15020	COG0123	including yeast histone deacetylase and acetoin utilization protein
WP7W18E02_15040	COG1199	ATP-dependent helicase activity
WP7W18E02_15070	COG1448	Aminotransferase
WP7W18E02_15080	COG3385	transposase activity
WP7W18E02_15100	COG0433	COG0433 Predicted ATPase
WP7W18E02_15130	COG2333	competence protein COMEC
WP7W18E02_15130	COG0658	competence protein
WP7W18E02_15170	COG3039	Transposase
WP7W18E02_15270	COG1132	(ABC) transporter
WP7W18E02_15280	COG1663	tetraacyldisaccharide 4'-kinase activity
WP7W18E02_15290	COG2835	tetraacyldisaccharide 4'-kinase activity
WP7W18E02_15300	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
WP7W18E02_15310	COG2197	response regulator
WP7W18E02_15320	COG0322	excinuclease ABC activity
WP7W18E02_15430	COG0625	glutathione transferase activity
WP7W18E02_15440	COG4584	PFAM Integrase catalytic
WP7W18E02_15450	COG1484	DNA-dependent DNA replication
WP7W18E02_15460	COG2261	transglycosylase associated protein
WP7W18E02_15470	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
WP7W18E02_15490	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
WP7W18E02_15530	COG2203	Gaf domain
WP7W18E02_15530	COG2199	diguanylate cyclase activity
WP7W18E02_15620	COG2119	membrane
WP7W18E02_15720	COG4138	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system
WP7W18E02_15730	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
WP7W18E02_15740	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
WP7W18E02_15750	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
WP7W18E02_15760	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
WP7W18E02_15770	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
WP7W18E02_15790	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
WP7W18E02_15800	COG0505	Belongs to the CarA family
WP7W18E02_15810	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
WP7W18E02_15820	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
WP7W18E02_15880	COG0513	Belongs to the DEAD box helicase family
WP7W18E02_15900	COG4104	PAAR repeat-containing protein
WP7W18E02_15920	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
WP7W18E02_15930	COG0765	amino acid transport
WP7W18E02_15940	COG1126	abc transporter atp-binding protein
WP7W18E02_15950	COG0493	'glutamate synthase
WP7W18E02_15960	COG0069	glutamate synthase activity
WP7W18E02_15960	COG0070	glutamate synthase
WP7W18E02_15960	COG0067	glutamate synthase
WP7W18E02_15970	COG1242	4 iron, 4 sulfur cluster binding
WP7W18E02_16080	COG1113	amino acid transport
WP7W18E02_16100	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
WP7W18E02_16110	COG0574	Belongs to the PEP-utilizing enzyme family
WP7W18E02_16110	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
WP7W18E02_16120	COG1119	ATPase activity
WP7W18E02_16160	COG1464	Belongs to the NlpA lipoprotein family
WP7W18E02_16170	COG0671	phosphoesterase, PA-phosphatase related
WP7W18E02_16180	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
WP7W18E02_16190	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
WP7W18E02_16210	COG0101	tRNA pseudouridine synthase activity
WP7W18E02_16220	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
WP7W18E02_16230	COG0285	dihydrofolate synthase activity
WP7W18E02_16240	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
WP7W18E02_16250	COG2920	part of a sulfur-relay system
WP7W18E02_16260	COG1289	transmembrane transporter activity
WP7W18E02_16270	COG0670	Belongs to the BI1 family
WP7W18E02_16320	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
WP7W18E02_16340	COG2175	clavaminate synthase activity
WP7W18E02_16350	COG3246	L-lysine catabolic process to acetate
WP7W18E02_16360	COG2814	Major facilitator Superfamily
WP7W18E02_16380	COG2855	membrane
WP7W18E02_16430	COG4447	cellulose binding
WP7W18E02_16470	COG0318	PFAM AMP-dependent synthetase and ligase
WP7W18E02_16480	COG0840	transmembrane signaling receptor activity
WP7W18E02_16500	COG3706	GGDEF domain
WP7W18E02_16510	COG0564	pseudouridine synthase activity
WP7W18E02_16540	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
WP7W18E02_16560	COG0625	glutathione transferase activity
WP7W18E02_16580	COG0367	asparagine synthase
WP7W18E02_16600	COG0647	UMP catabolic process
WP7W18E02_16610	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
WP7W18E02_16620	COG1902	pentaerythritol trinitrate reductase activity
WP7W18E02_16630	COG1253	flavin adenine dinucleotide binding
WP7W18E02_16650	COG0247	lactate metabolic process
WP7W18E02_16650	COG0277	FAD linked oxidase domain protein
WP7W18E02_16670	COG2050	protein possibly involved in aromatic compounds catabolism
WP7W18E02_16680	COG0513	Belongs to the DEAD box helicase family
WP7W18E02_16700	COG5001	Diguanylate cyclase
WP7W18E02_16710	COG0583	DNA-binding transcription factor activity
WP7W18E02_16720	COG2814	Major facilitator Superfamily
WP7W18E02_16730	COG2056	Na+-H+ antiporter family
WP7W18E02_16740	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
WP7W18E02_16770	COG0483	inositol monophosphate 1-phosphatase activity
WP7W18E02_16800	COG0625	glutathione transferase activity
WP7W18E02_16820	COG0601	transmembrane transport
WP7W18E02_16830	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
WP7W18E02_16850	COG2814	Major facilitator Superfamily
WP7W18E02_16880	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
WP7W18E02_16890	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
WP7W18E02_16900	COG0404	The glycine cleavage system catalyzes the degradation of glycine
WP7W18E02_16910	COG0509	glycine decarboxylation via glycine cleavage system
WP7W18E02_16920	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
WP7W18E02_16920	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
WP7W18E02_17040	COG3634	alkyl hydroperoxide reductase activity
WP7W18E02_17060	COG0517	IMP dehydrogenase activity
WP7W18E02_17070	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
WP7W18E02_17080	COG0343	queuine tRNA-ribosyltransferase activity
WP7W18E02_17090	COG1862	Preprotein translocase
WP7W18E02_17100	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
WP7W18E02_17110	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
WP7W18E02_17140	COG0826	peptidase U32
WP7W18E02_17150	COG0826	peptidase U32
WP7W18E02_17160	COG3154	lipid carrier protein
WP7W18E02_17200	COG1104	cysteine desulfurase activity
WP7W18E02_17210	COG0822	iron-sulfur transferase activity
WP7W18E02_17230	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
WP7W18E02_17240	COG0443	Heat shock 70 kDa protein
WP7W18E02_17250	COG0633	Ferredoxin
WP7W18E02_17270	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
WP7W18E02_17290	COG0105	UTP biosynthetic process
WP7W18E02_17300	COG0820	rRNA (adenine-C2-)-methyltransferase activity
WP7W18E02_17340	COG0124	histidyl-tRNA synthetase
WP7W18E02_17350	COG2976	Protein conserved in bacteria
WP7W18E02_17360	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
WP7W18E02_17370	COG1160	GTP binding
WP7W18E02_17390	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
WP7W18E02_17400	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
WP7W18E02_17400	COG0047	phosphoribosylformylglycinamidine synthase activity
WP7W18E02_17410	COG1007	ATP synthesis coupled electron transport
WP7W18E02_17420	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
WP7W18E02_17440	COG0713	ATP synthesis coupled electron transport
WP7W18E02_17450	COG0839	Belongs to the complex I subunit 6 family
WP7W18E02_17460	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
WP7W18E02_17470	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
WP7W18E02_17480	COG1034	ATP synthesis coupled electron transport
WP7W18E02_17510	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
WP7W18E02_17510	COG0649	NAD binding
WP7W18E02_17520	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
WP7W18E02_17530	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
WP7W18E02_17540	COG1360	Flagellar Motor Protein
WP7W18E02_17550	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
WP7W18E02_17560	COG2801	Transposase and inactivated derivatives
WP7W18E02_17580	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
WP7W18E02_17600	COG2801	Transposase and inactivated derivatives
WP7W18E02_17640	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
WP7W18E02_17660	COG3770	Murein endopeptidase that cleaves the D-alanyl-meso-2,6- diamino-pimelyl amide bond that connects peptidoglycan strands. Likely plays a role in the removal of murein from the sacculus
WP7W18E02_17680	COG0724	RNA recognition motif
WP7W18E02_17690	COG4989	oxidoreductase activity
WP7W18E02_17740	COG3437	response regulator, receiver
WP7W18E02_17750	COG0583	DNA-binding transcription factor activity
WP7W18E02_17770	COG5001	Diguanylate cyclase
WP7W18E02_17770	COG3300	MHYT domain
WP7W18E02_17780	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
WP7W18E02_17790	COG0778	Nitroreductase
WP7W18E02_17840	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
WP7W18E02_17850	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
WP7W18E02_17860	COG0539	negative regulation of cytoplasmic translation
WP7W18E02_17870	COG0776	regulation of translation
WP7W18E02_17890	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
WP7W18E02_17930	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
WP7W18E02_17940	COG0602	queuosine metabolic process
WP7W18E02_17950	COG3530	Putative quorum-sensing-regulated virulence factor
WP7W18E02_17960	COG2096	Adenosyltransferase
WP7W18E02_17970	COG2916	Histone family protein nucleoid-structuring protein H-NS
WP7W18E02_17980	COG1757	Na H antiporter
WP7W18E02_17990	COG1435	thymidine kinase activity
WP7W18E02_18020	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
WP7W18E02_18030	COG3550	peptidyl-serine autophosphorylation
WP7W18E02_18220	COG5001	Diguanylate cyclase
WP7W18E02_18220	COG4251	negative regulation of phosphorylation
WP7W18E02_18220	COG2203	Gaf domain
WP7W18E02_18220	COG3706	GGDEF domain
WP7W18E02_18230	COG3300	MHYT domain
WP7W18E02_18230	COG5001	Diguanylate cyclase
WP7W18E02_18240	COG1484	DNA-dependent DNA replication
WP7W18E02_18270	COG0745	RESPONSE REGULATOR receiver
WP7W18E02_18280	COG0745	RESPONSE REGULATOR receiver
WP7W18E02_18300	COG3039	Transposase
WP7W18E02_18340	COG2197	response regulator
WP7W18E02_18410	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
WP7W18E02_18530	COG0629	single-stranded DNA binding
WP7W18E02_18540	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
WP7W18E02_18550	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
WP7W18E02_18560	COG1397	ADP-ribosylglycohydrolase
WP7W18E02_18610	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
WP7W18E02_18710	COG3039	Transposase
WP7W18E02_18750	COG3039	Transposase
WP7W18E02_18770	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
WP7W18E02_18790	COG3436	PFAM IS66 Orf2 family protein
WP7W18E02_18810	COG4372	Transposase
WP7W18E02_18870	COG0469	pyruvate kinase activity
WP7W18E02_18880	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
WP7W18E02_18890	COG1085	galactose-1-phosphate uridylyltransferase
WP7W18E02_18900	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
WP7W18E02_18910	COG1609	Transcriptional regulator
WP7W18E02_18920	COG3039	Transposase
WP7W18E02_18990	COG2223	nitrite transmembrane transporter activity
WP7W18E02_19000	COG3250	beta-galactosidase activity
WP7W18E02_19020	COG2226	methyltransferase
WP7W18E02_19070	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
WP7W18E02_19100	COG2910	NAD(P)H-binding
WP7W18E02_19130	COG2207	Transcriptional regulator
WP7W18E02_19130	COG3708	Transcriptional regulator
WP7W18E02_19140	COG4774	siderophore transport
WP7W18E02_19170	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
WP7W18E02_19180	COG0617	tRNA 3'-terminal CCA addition
WP7W18E02_19180	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
WP7W18E02_19180	COG3620	sequence-specific DNA binding
WP7W18E02_19210	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
WP7W18E02_19220	COG3046	protein related to deoxyribodipyrimidine photolyase
WP7W18E02_19250	COG4235	cytochrome complex assembly
WP7W18E02_19250	COG3088	subunit of a heme lyase
WP7W18E02_19260	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
WP7W18E02_19270	COG1138	Cytochrome C-type biogenesis protein
WP7W18E02_19280	COG3301	Polysulphide reductase, NrfD
WP7W18E02_19290	COG0437	4 iron, 4 sulfur cluster binding
WP7W18E02_19300	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
WP7W18E02_19380	COG0247	lactate metabolic process
WP7W18E02_19390	COG3075	Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses fumarate or nitrate as electron acceptor
WP7W18E02_19400	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
WP7W18E02_19410	COG3012	SEC-C Motif Domain Protein
WP7W18E02_19430	COG1940	carbohydrate kinase activity
WP7W18E02_19430	COG1846	Transcriptional regulator
WP7W18E02_19440	COG3290	protein histidine kinase activity
WP7W18E02_19450	COG4565	transcriptional regulatory protein
WP7W18E02_19490	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
WP7W18E02_19500	COG0569	domain protein
WP7W18E02_19500	COG2985	domain, Protein
WP7W18E02_19510	COG0556	nucleotide-excision repair
WP7W18E02_19530	COG0586	Pfam SNARE associated Golgi protein
WP7W18E02_19540	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
WP7W18E02_19550	COG3067	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
WP7W18E02_19570	COG2719	SpoVR family
WP7W18E02_19580	COG2718	Belongs to the UPF0229 family
WP7W18E02_19590	COG2766	serine protein kinase
WP7W18E02_19600	COG0514	ATP-dependent DNA helicase (RecQ)
WP7W18E02_19610	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
WP7W18E02_19620	COG0814	amino acid
WP7W18E02_19680	COG0058	SHG alpha-glucan phosphorylase activity
WP7W18E02_19700	COG0471	metal ion transport
WP7W18E02_19710	COG3118	belongs to the thioredoxin family
WP7W18E02_19730	COG1132	(ABC) transporter
WP7W18E02_19740	COG1132	(ABC) transporter
WP7W18E02_19770	COG2501	S4 domain
WP7W18E02_19830	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
WP7W18E02_19840	COG2329	Antibiotic biosynthesis monooxygenase
WP7W18E02_19860	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
WP7W18E02_19870	COG0673	inositol 2-dehydrogenase activity
WP7W18E02_19880	COG0583	DNA-binding transcription factor activity
WP7W18E02_19900	COG1560	Kdo2-lipid A biosynthetic process
WP7W18E02_19910	COG1560	Kdo2-lipid A biosynthetic process
WP7W18E02_19960	COG0417	DNA replication proofreading
WP7W18E02_19990	COG0307	riboflavin synthase, alpha
WP7W18E02_20010	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
WP7W18E02_20020	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
WP7W18E02_20030	COG0697	spore germination
WP7W18E02_20040	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
WP7W18E02_20130	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
WP7W18E02_20140	COG3099	Belongs to the UPF0263 family
WP7W18E02_20150	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
WP7W18E02_20160	COG2894	cell division
WP7W18E02_20170	COG0850	regulation of cytokinetic process
WP7W18E02_20180	COG3100	YcgL domain-containing protein
WP7W18E02_20200	COG1760	l-serine dehydratase
WP7W18E02_20210	COG1760	l-serine dehydratase
WP7W18E02_20220	COG3123	guanosine phosphorylase activity
WP7W18E02_20230	COG1301	dicarboxylic acid transport
WP7W18E02_20260	COG2067	long-chain fatty acid transport protein
WP7W18E02_20270	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
WP7W18E02_20280	COG2067	long-chain fatty acid transport protein
WP7W18E02_20290	COG2067	long-chain fatty acid transport protein
WP7W18E02_20310	COG1595	DNA-templated transcription, initiation
WP7W18E02_20370	COG0714	Associated with various cellular activities
WP7W18E02_20380	COG0183	Belongs to the thiolase family
WP7W18E02_20390	COG1024	Enoyl-CoA hydratase
WP7W18E02_20390	COG1250	3-hydroxyacyl-CoA dehydrogenase
WP7W18E02_20410	COG4681	YaeQ
WP7W18E02_20450	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
WP7W18E02_20480	COG3134	Outer membrane lipoprotein
WP7W18E02_20490	COG0318	PFAM AMP-dependent synthetase and ligase
WP7W18E02_20500	COG2378	regulation of single-species biofilm formation
WP7W18E02_20520	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
WP7W18E02_20520	COG0140	phosphoribosyl-ATP diphosphatase activity
WP7W18E02_20530	COG0107	imidazoleglycerol-phosphate synthase activity
WP7W18E02_20540	COG2205	protein histidine kinase activity
WP7W18E02_20540	COG0784	Response regulator, receiver
WP7W18E02_20540	COG2198	Histidine kinase
WP7W18E02_20560	COG3437	response regulator, receiver
WP7W18E02_20570	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
WP7W18E02_20580	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
WP7W18E02_20590	COG0131	Imidazoleglycerol-phosphate dehydratase
WP7W18E02_20590	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
WP7W18E02_20600	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
WP7W18E02_20610	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
WP7W18E02_20620	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
WP7W18E02_20640	COG1199	ATP-dependent helicase activity
WP7W18E02_20650	COG1214	PFAM Peptidase M22, glycoprotease
WP7W18E02_20670	COG0596	Alpha beta hydrolase
WP7W18E02_20680	COG0318	PFAM AMP-dependent synthetase and ligase
WP7W18E02_20690	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
WP7W18E02_20710	COG0697	spore germination
WP7W18E02_20730	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
WP7W18E02_20740	COG2832	Protein of unknown function (DUF454)
WP7W18E02_20750	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
WP7W18E02_20770	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
WP7W18E02_20780	COG1335	isochorismatase
WP7W18E02_20840	COG2197	response regulator
WP7W18E02_20850	COG0617	tRNA 3'-terminal CCA addition
WP7W18E02_20850	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
WP7W18E02_20850	COG0517	IMP dehydrogenase activity
WP7W18E02_20860	COG1643	Atp-dependent helicase
WP7W18E02_20880	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
WP7W18E02_20900	COG3437	response regulator, receiver
WP7W18E02_20910	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
WP7W18E02_20920	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
WP7W18E02_20930	COG0709	Synthesizes selenophosphate from selenide and ATP
WP7W18E02_20950	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
WP7W18E02_20960	COG0840	transmembrane signaling receptor activity
WP7W18E02_20970	COG1254	Belongs to the acylphosphatase family
WP7W18E02_20990	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
WP7W18E02_20990	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
WP7W18E02_21000	COG0489	protein tyrosine kinase activity
WP7W18E02_21010	COG0572	uridine kinase
WP7W18E02_21020	COG0717	Belongs to the dCTP deaminase family
WP7W18E02_21030	COG0306	phosphate transporter
WP7W18E02_21040	COG4584	PFAM Integrase catalytic
WP7W18E02_21050	COG4584	PFAM Integrase catalytic
WP7W18E02_21060	COG1484	DNA-dependent DNA replication
WP7W18E02_21070	COG1530	ribonuclease E activity
WP7W18E02_21090	COG0546	phosphoglycolate phosphatase activity
WP7W18E02_21100	COG0424	maF-like protein
WP7W18E02_21120	COG1399	metal-binding, possibly nucleic acid-binding protein
WP7W18E02_21130	COG0333	Belongs to the bacterial ribosomal protein bL32 family
WP7W18E02_21140	COG0416	fatty acid biosynthetic process
WP7W18E02_21150	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
WP7W18E02_21170	COG1028	Short-chain dehydrogenase reductase Sdr
WP7W18E02_21180	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
WP7W18E02_21200	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
WP7W18E02_21210	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
WP7W18E02_21220	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
WP7W18E02_21230	COG0470	DNA polymerase III
WP7W18E02_21240	COG0084	hydrolase, TatD family'
WP7W18E02_21270	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
WP7W18E02_21270	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
WP7W18E02_21280	COG3008	intermembrane lipid transfer
WP7W18E02_21290	COG2995	paraquat-inducible protein a
WP7W18E02_21310	COG3141	response to X-ray
WP7W18E02_21430	COG1067	ATP-dependent peptidase activity
WP7W18E02_21440	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
WP7W18E02_21460	COG0488	(ABC) transporter
WP7W18E02_21480	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
WP7W18E02_21480	COG0116	Belongs to the methyltransferase superfamily
WP7W18E02_21500	COG0167	dihydroorotate dehydrogenase activity
WP7W18E02_21510	COG2902	Dehydrogenase
WP7W18E02_21530	COG0308	aminopeptidase N
WP7W18E02_21550	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
WP7W18E02_21560	COG1956	GAF domain-containing protein
WP7W18E02_21580	COG3278	Belongs to the heme-copper respiratory oxidase family
WP7W18E02_21610	COG2010	Cytochrome c
WP7W18E02_21660	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
WP7W18E02_21670	COG0589	response to stress
WP7W18E02_21680	COG0037	tRNA processing
WP7W18E02_21720	COG1869	D-ribose catabolic process
WP7W18E02_21730	COG1129	ABC transporter
WP7W18E02_21740	COG1172	Belongs to the binding-protein-dependent transport system permease family
WP7W18E02_21750	COG1879	ABC-type sugar transport system periplasmic component
WP7W18E02_21760	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
WP7W18E02_21770	COG1609	Transcriptional regulator
WP7W18E02_21780	COG5001	Diguanylate cyclase
WP7W18E02_21780	COG3300	MHYT domain
WP7W18E02_21830	COG0784	Response regulator, receiver
WP7W18E02_21830	COG2205	protein histidine kinase activity
WP7W18E02_21840	COG0776	regulation of translation
WP7W18E02_21850	COG0072	phenylalanine-tRNA ligase activity
WP7W18E02_21850	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
WP7W18E02_21860	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
WP7W18E02_21870	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
WP7W18E02_21880	COG0291	Belongs to the bacterial ribosomal protein bL35 family
WP7W18E02_21890	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
WP7W18E02_21900	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
WP7W18E02_21950	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
WP7W18E02_21970	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
WP7W18E02_21990	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
WP7W18E02_22000	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
WP7W18E02_22010	COG3313	Fe-S protein
WP7W18E02_22020	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
WP7W18E02_22020	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
WP7W18E02_22020	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
WP7W18E02_22030	COG1105	Belongs to the carbohydrate kinase PfkB family
WP7W18E02_22040	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
WP7W18E02_22040	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
WP7W18E02_22050	COG1609	Transcriptional regulator
WP7W18E02_22060	COG0814	amino acid
WP7W18E02_22070	COG3788	relative of glutathione S-transferase, MAPEG superfamily
WP7W18E02_22080	COG0513	Belongs to the DEAD box helicase family
WP7W18E02_22100	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
WP7W18E02_22110	COG2890	protein-(glutamine-N5) methyltransferase activity
WP7W18E02_22120	COG2840	Smr protein MutS2
WP7W18E02_22140	COG0406	alpha-ribazole phosphatase activity
WP7W18E02_22190	COG2824	Alkylphosphonate utilization operon protein PhnA
WP7W18E02_22210	COG1280	lysine exporter protein (LysE YggA)
WP7W18E02_22320	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
WP7W18E02_22330	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
WP7W18E02_22340	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
WP7W18E02_22360	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
WP7W18E02_22370	COG1434	Gram-negative-bacterium-type cell wall biogenesis
WP7W18E02_22390	COG0205	6-phosphofructokinase activity
WP7W18E02_22400	COG1473	amidohydrolase
WP7W18E02_22410	COG1011	Hydrolase
WP7W18E02_22420	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
WP7W18E02_22440	COG3593	DNA synthesis involved in DNA repair
WP7W18E02_22470	COG0583	DNA-binding transcription factor activity
WP7W18E02_22480	COG0730	response to heat
WP7W18E02_22510	COG1181	Belongs to the D-alanine--D-alanine ligase family
WP7W18E02_22530	COG0386	Belongs to the glutathione peroxidase family
WP7W18E02_22540	COG0513	Belongs to the DEAD box helicase family
WP7W18E02_22560	COG1742	UPF0060 membrane protein
WP7W18E02_22600	COG3039	Transposase
WP7W18E02_22630	COG0583	DNA-binding transcription factor activity
WP7W18E02_22640	COG1028	Short-chain dehydrogenase reductase Sdr
WP7W18E02_22650	COG2723	6-phospho-beta-galactosidase activity
WP7W18E02_22660	COG0583	DNA-binding transcription factor activity
WP7W18E02_22670	COG3706	GGDEF domain
WP7W18E02_22690	COG0243	molybdopterin cofactor binding
WP7W18E02_22700	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
WP7W18E02_22730	COG0583	DNA-binding transcription factor activity
WP7W18E02_22750	COG1879	ABC-type sugar transport system periplasmic component
WP7W18E02_22760	COG1129	ABC transporter
WP7W18E02_22770	COG1172	Belongs to the binding-protein-dependent transport system permease family
WP7W18E02_22780	COG1172	Belongs to the binding-protein-dependent transport system permease family
WP7W18E02_22790	COG2963	transposase activity
WP7W18E02_22840	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
WP7W18E02_22870	COG0656	L-ascorbic acid biosynthetic process
WP7W18E02_22920	COG5002	protein histidine kinase activity
WP7W18E02_22940	COG0667	Aldo Keto reductase
WP7W18E02_22960	COG2814	Major facilitator Superfamily
WP7W18E02_22990	COG0667	Aldo Keto reductase
WP7W18E02_23000	COG1979	alcohol dehydrogenase
WP7W18E02_23010	COG0583	DNA-binding transcription factor activity
WP7W18E02_23030	COG0583	DNA-binding transcription factor activity
WP7W18E02_23040	COG0730	response to heat
WP7W18E02_23060	COG1028	Short-chain dehydrogenase reductase Sdr
WP7W18E02_23080	COG1024	Enoyl-CoA hydratase
WP7W18E02_23090	COG1024	Enoyl-CoA hydratase
WP7W18E02_23100	COG1960	acyl-CoA dehydrogenase activity
WP7W18E02_23120	COG1960	acyl-CoA dehydrogenase activity
WP7W18E02_23130	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
WP7W18E02_23140	COG1024	Enoyl-CoA hydratase
WP7W18E02_23200	COG1584	GPR1 FUN34 yaaH family protein
WP7W18E02_23230	COG1115	amino acid carrier protein
WP7W18E02_23240	COG1024	Enoyl-CoA hydratase
WP7W18E02_23270	COG3162	membrane
WP7W18E02_23280	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
WP7W18E02_23290	COG0488	(ABC) transporter
WP7W18E02_23300	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
WP7W18E02_23310	COG0776	regulation of translation
WP7W18E02_23320	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
WP7W18E02_23330	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
WP7W18E02_23340	COG0740	serine-type endopeptidase activity
WP7W18E02_23350	COG0544	peptidyl-prolyl cis-trans isomerase activity
WP7W18E02_23380	COG4591	ABC-type transport system involved in lipoprotein release permease component
WP7W18E02_23390	COG1136	(ABC) transporter
WP7W18E02_23400	COG4591	ABC-type transport system involved in lipoprotein release permease component
WP7W18E02_23420	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
WP7W18E02_23430	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
WP7W18E02_23440	COG4166	transmembrane transport
WP7W18E02_23450	COG0697	spore germination
WP7W18E02_23470	COG2062	phosphohistidine phosphatase, SixA
WP7W18E02_23510	COG3039	Transposase
WP7W18E02_23540	COG0518	GMP synthase (glutamine-hydrolyzing) activity
WP7W18E02_23540	COG0519	Catalyzes the synthesis of GMP from XMP
WP7W18E02_23550	COG0516	GMP reductase activity
WP7W18E02_23550	COG0517	IMP dehydrogenase activity
WP7W18E02_23570	COG1874	Beta-galactosidase
WP7W18E02_23570	COG0366	Alpha amylase catalytic
WP7W18E02_23590	COG1570	exodeoxyribonuclease VII activity
WP7W18E02_23610	COG2885	chlorophyll binding
WP7W18E02_23620	COG2199	diguanylate cyclase activity
WP7W18E02_23650	COG2154	pterin-4-alpha-carbinolamine dehydratase
WP7W18E02_23670	COG3768	UPF0283 membrane protein
WP7W18E02_23680	COG3106	COG3106 Predicted ATPase
WP7W18E02_23710	COG1842	Phage shock protein A
WP7W18E02_23720	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
WP7W18E02_23740	COG4168	peptide transport system, permease
WP7W18E02_23750	COG4171	peptide transport system, permease
WP7W18E02_23780	COG4172	Belongs to the ABC transporter superfamily
WP7W18E02_23800	COG1609	Transcriptional regulator
WP7W18E02_23810	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
WP7W18E02_23810	COG1263	PTS System
WP7W18E02_23820	COG2723	6-phospho-beta-galactosidase activity
WP7W18E02_23830	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
WP7W18E02_23840	COG1286	toxin biosynthetic process
WP7W18E02_23850	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
WP7W18E02_23860	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
WP7W18E02_23870	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
WP7W18E02_23880	COG1674	ftsk spoiiie
WP7W18E02_23880	COG0531	amino acid
WP7W18E02_23900	COG0686	Belongs to the AlaDH PNT family
WP7W18E02_23910	COG0492	ferredoxin-NADP+ reductase activity
WP7W18E02_23920	COG3706	GGDEF domain
WP7W18E02_23930	COG3134	Outer membrane lipoprotein
WP7W18E02_23940	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
WP7W18E02_23950	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
WP7W18E02_23960	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
WP7W18E02_23970	COG0542	response to heat
WP7W18E02_23980	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
WP7W18E02_23990	COG1278	Cold shock
WP7W18E02_24000	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
WP7W18E02_24030	COG1944	ATP diphosphatase activity
WP7W18E02_24040	COG2116	formate transmembrane transporter activity
WP7W18E02_24050	COG1882	Formate acetyltransferase
WP7W18E02_24060	COG2983	Belongs to the UPF0260 family
WP7W18E02_24080	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
WP7W18E02_24090	COG0045	succinate-CoA ligase (ADP-forming) activity
WP7W18E02_24100	COG0508	dehydrogenase complex catalyzes the overall conversion of
WP7W18E02_24110	COG0567	Dehydrogenase, E1 component
WP7W18E02_24130	COG1053	succinate dehydrogenase
WP7W18E02_24140	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
WP7W18E02_24190	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
WP7W18E02_24200	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
WP7W18E02_24200	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
WP7W18E02_24230	COG3069	C4-dicarboxylate transmembrane transporter activity
WP7W18E02_24260	COG1451	nucleotide metabolic process
WP7W18E02_24300	COG1028	Short-chain dehydrogenase reductase Sdr
WP7W18E02_24330	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
WP7W18E02_24340	COG0800	Aldolase
WP7W18E02_24350	COG2731	YhcH YjgK YiaL family protein
WP7W18E02_24380	COG1172	Belongs to the binding-protein-dependent transport system permease family
WP7W18E02_24390	COG1129	ABC transporter
WP7W18E02_24400	COG1879	ABC-type sugar transport system periplasmic component
WP7W18E02_24410	COG1069	ribulokinase activity
WP7W18E02_24430	COG2160	L-arabinose isomerase activity
WP7W18E02_24440	COG0583	DNA-binding transcription factor activity
WP7W18E02_24450	COG0436	Aminotransferase
WP7W18E02_24460	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
WP7W18E02_24490	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
WP7W18E02_24490	COG0392	lysyltransferase activity
WP7W18E02_24520	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
WP7W18E02_24520	COG0392	lysyltransferase activity
WP7W18E02_24530	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
WP7W18E02_24540	COG2925	Exonuclease
WP7W18E02_24560	COG3345	alpha-galactosidase
WP7W18E02_24570	COG1380	Effector of murein hydrolase LrgA
WP7W18E02_24580	COG1346	cytolysis
WP7W18E02_24590	COG0295	cytidine deaminase activity
WP7W18E02_24600	COG1022	Amp-dependent synthetase and ligase
WP7W18E02_24630	COG0861	Integral membrane protein TerC family
WP7W18E02_24640	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
WP7W18E02_24650	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
WP7W18E02_24660	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
WP7W18E02_24740	COG4771	TonB-dependent receptor
WP7W18E02_24750	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
WP7W18E02_24760	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
WP7W18E02_24770	COG1120	ATPase activity
WP7W18E02_24790	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
WP7W18E02_24800	COG0300	oxidoreductase activity
WP7W18E02_24800	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
WP7W18E02_24800	COG1028	Short-chain dehydrogenase reductase Sdr
WP7W18E02_24800	COG3321	synthase
WP7W18E02_24800	COG0318	PFAM AMP-dependent synthetase and ligase
WP7W18E02_24830	COG1028	Short-chain dehydrogenase reductase Sdr
WP7W18E02_24840	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
WP7W18E02_24850	COG3433	isochorismatase activity
WP7W18E02_24850	COG1535	isochorismatase
WP7W18E02_24860	COG1021	2,3-dihydroxybenzoate-AMP ligase
WP7W18E02_24900	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
WP7W18E02_24910	COG5001	Diguanylate cyclase
WP7W18E02_24910	COG3300	MHYT domain
WP7W18E02_24940	COG0840	transmembrane signaling receptor activity
WP7W18E02_24950	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
WP7W18E02_24970	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
WP7W18E02_24980	COG0563	adenylate kinase activity
WP7W18E02_24990	COG0326	Molecular chaperone. Has ATPase activity
WP7W18E02_25000	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
WP7W18E02_25010	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
WP7W18E02_25020	COG0298	carbon dioxide binding
WP7W18E02_25040	COG0309	Hydrogenase expression formation protein (HypE)
WP7W18E02_25050	COG0375	protein maturation
WP7W18E02_25070	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
WP7W18E02_25080	COG3842	ATPase activity
WP7W18E02_25090	COG0444	Belongs to the ABC transporter superfamily
WP7W18E02_25100	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
WP7W18E02_25110	COG0601	transmembrane transport
WP7W18E02_25130	COG1773	rubredoxin
WP7W18E02_25140	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
WP7W18E02_25150	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
WP7W18E02_25160	COG5557	Pfam Polysulphide reductase, NrfD
WP7W18E02_25170	COG0437	4 iron, 4 sulfur cluster binding
WP7W18E02_25180	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
WP7W18E02_25190	COG3039	Transposase
WP7W18E02_25200	COG3039	Transposase
WP7W18E02_25210	COG3039	Transposase
WP7W18E02_25240	COG0659	secondary active sulfate transmembrane transporter activity
WP7W18E02_25250	COG2308	Evidence 4 Homologs of previously reported genes of
WP7W18E02_25320	COG0672	)-iron permease
WP7W18E02_25380	COG2814	Major facilitator Superfamily
WP7W18E02_25420	COG1136	(ABC) transporter
WP7W18E02_25470	COG5433	transposase activity
WP7W18E02_25480	COG3039	Transposase
WP7W18E02_25510	COG1139	Iron-sulfur cluster binding protein
WP7W18E02_25520	COG0247	lactate metabolic process
WP7W18E02_25530	COG1620	l-lactate permease
WP7W18E02_25540	COG0583	DNA-binding transcription factor activity
WP7W18E02_25560	COG2315	Protein conserved in bacteria
WP7W18E02_25590	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
WP7W18E02_25600	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
WP7W18E02_25600	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
WP7W18E02_25620	COG0527	aspartate kinase activity
WP7W18E02_25640	COG1368	sulfuric ester hydrolase activity
WP7W18E02_25650	COG1619	proteins homologs of microcin C7 resistance protein MccF
WP7W18E02_25660	COG0393	Putative heavy-metal-binding
WP7W18E02_25680	COG1252	NADH dehydrogenase
WP7W18E02_25690	COG3150	esterase
WP7W18E02_25730	COG2354	Protein conserved in bacteria
WP7W18E02_25750	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
WP7W18E02_25760	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
WP7W18E02_25840	COG0537	adenosine 5'-monophosphoramidase activity
WP7W18E02_25870	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
WP7W18E02_25900	COG0675	Transposase, IS605 OrfB family
WP7W18E02_25920	COG1301	dicarboxylic acid transport
WP7W18E02_25940	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
WP7W18E02_25950	COG0861	Integral membrane protein TerC family
WP7W18E02_25970	COG0444	Belongs to the ABC transporter superfamily
WP7W18E02_25980	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
WP7W18E02_25990	COG0601	transmembrane transport
WP7W18E02_26010	COG2095	MarC family integral membrane protein
WP7W18E02_26020	COG1012	belongs to the aldehyde dehydrogenase family
WP7W18E02_26020	COG1454	alcohol dehydrogenase
WP7W18E02_26040	COG3275	phosphorelay sensor kinase activity
WP7W18E02_26050	COG3279	Response regulator of the LytR AlgR family
WP7W18E02_26060	COG1966	Carbon starvation protein
WP7W18E02_26070	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
WP7W18E02_26070	COG3264	Mechanosensitive ion channel
WP7W18E02_26090	COG1566	PFAM secretion protein HlyD family protein
WP7W18E02_26100	COG1061	Type III restriction enzyme res subunit
WP7W18E02_26110	COG2027	D-alanyl-D-alanine carboxypeptidase
WP7W18E02_26130	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
WP7W18E02_26150	COG0436	Aminotransferase
WP7W18E02_26160	COG1288	antiporter activity
WP7W18E02_26170	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
WP7W18E02_26210	COG0697	spore germination
WP7W18E02_26220	COG4657	Part of a membrane complex involved in electron transport
WP7W18E02_26230	COG2878	Part of a membrane complex involved in electron transport
WP7W18E02_26240	COG4656	Part of a membrane complex involved in electron transport
WP7W18E02_26250	COG4658	electron transport chain
WP7W18E02_26260	COG4659	FMN binding
WP7W18E02_26270	COG4660	Part of a membrane complex involved in electron transport
WP7W18E02_26280	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
WP7W18E02_26290	COG0346	lactoylglutathione lyase activity
WP7W18E02_26320	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
WP7W18E02_26410	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
WP7W18E02_26440	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
WP7W18E02_26440	COG0301	tRNA thio-modification
WP7W18E02_26460	COG4953	penicillin-binding protein 1C
WP7W18E02_26470	COG2373	Large extracellular alpha-helical protein
WP7W18E02_26490	COG0628	permease
WP7W18E02_26540	COG2271	Major facilitator Superfamily
WP7W18E02_26550	COG3039	Transposase
WP7W18E02_26560	COG0446	pyridine nucleotide-disulphide oxidoreductase
WP7W18E02_26580	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
WP7W18E02_26660	COG0438	transferase activity, transferring glycosyl groups
WP7W18E02_26660	COG1216	Glycosyl transferase, family 2
WP7W18E02_26670	COG0438	transferase activity, transferring glycosyl groups
WP7W18E02_26670	COG1216	Glycosyl transferase, family 2
WP7W18E02_26720	COG3039	Transposase
WP7W18E02_26780	COG0438	transferase activity, transferring glycosyl groups
WP7W18E02_26780	COG1216	Glycosyl transferase, family 2
WP7W18E02_26800	COG1210	Utp--glucose-1-phosphate uridylyltransferase
WP7W18E02_26820	COG1091	dTDP-4-dehydrorhamnose reductase activity
WP7W18E02_26870	COG4160	amino acid transport
WP7W18E02_26890	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
WP7W18E02_26910	COG2431	L-lysine efflux transmembrane transporter activity
WP7W18E02_26920	COG1228	amidohydrolase
WP7W18E02_26930	COG0675	Transposase, IS605 OrfB family
WP7W18E02_26950	COG1228	amidohydrolase
WP7W18E02_26980	COG1393	Belongs to the ArsC family
WP7W18E02_27000	COG4783	chaperone-mediated protein folding
WP7W18E02_27050	COG0675	Transposase, IS605 OrfB family
WP7W18E02_27080	COG3842	ATPase activity
WP7W18E02_27090	COG3833	ABC-type maltose transport systems, permease component
WP7W18E02_27100	COG1175	transmembrane transport
WP7W18E02_27110	COG2182	Extracellular solute-binding protein
WP7W18E02_27120	COG3081	Nucleoid-associated protein
WP7W18E02_27130	COG3082	Protein of unknown function (DUF1414)
WP7W18E02_27140	COG3083	sulfuric ester hydrolase activity
WP7W18E02_27150	COG4771	TonB-dependent receptor
WP7W18E02_27170	COG1770	oligopeptidase
WP7W18E02_27210	COG4574	serine-type endopeptidase inhibitor activity
WP7W18E02_27220	COG3085	chromosome segregation
WP7W18E02_27240	COG0287	Prephenate dehydrogenase
WP7W18E02_27240	COG1605	Chorismate mutase
WP7W18E02_27250	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
WP7W18E02_27260	COG0584	glycerophosphoryl diester phosphodiesterase
WP7W18E02_27280	COG1349	DNA-binding transcription factor activity
WP7W18E02_27290	COG2271	Major facilitator Superfamily
WP7W18E02_27300	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
WP7W18E02_27310	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
WP7W18E02_27320	COG0583	DNA-binding transcription factor activity
WP7W18E02_27360	COG0656	L-ascorbic acid biosynthetic process
WP7W18E02_27370	COG2814	Major facilitator Superfamily
WP7W18E02_27390	COG1294	oxidase, subunit
WP7W18E02_27410	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
WP7W18E02_27450	COG1595	DNA-templated transcription, initiation
WP7W18E02_27490	COG2979	Protein of unknown function (DUF533)
WP7W18E02_27570	COG2807	transmembrane transport
WP7W18E02_27580	COG1187	pseudouridine synthase activity
WP7W18E02_27590	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
WP7W18E02_27630	COG5433	transposase activity
WP7W18E02_27690	COG1166	arginine decarboxylase activity
WP7W18E02_27700	COG2195	Cleaves the N-terminal amino acid of tripeptides
WP7W18E02_27710	COG0675	Transposase, IS605 OrfB family
WP7W18E02_27750	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
WP7W18E02_27780	COG0583	DNA-binding transcription factor activity
WP7W18E02_27800	COG2759	Belongs to the formate--tetrahydrofolate ligase family
WP7W18E02_27810	COG0840	transmembrane signaling receptor activity
WP7W18E02_27820	COG0302	gtp cyclohydrolase
WP7W18E02_27840	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
WP7W18E02_27850	COG0596	Alpha beta hydrolase
WP7W18E02_27860	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
WP7W18E02_27890	COG0314	molybdopterin synthase activity
WP7W18E02_27900	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
WP7W18E02_27910	COG0315	cyclic pyranopterin monophosphate synthase activity
WP7W18E02_27920	COG0521	Mo-molybdopterin cofactor biosynthetic process
WP7W18E02_27930	COG3005	denitrification pathway
WP7W18E02_27950	COG0348	domain, Protein
WP7W18E02_27960	COG0437	4 iron, 4 sulfur cluster binding
WP7W18E02_27970	COG0243	molybdopterin cofactor binding
WP7W18E02_27990	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
WP7W18E02_28000	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
WP7W18E02_28010	COG3850	Histidine kinase
WP7W18E02_28020	COG2197	response regulator
WP7W18E02_28070	COG0391	Required for morphogenesis under gluconeogenic growth conditions
WP7W18E02_28090	COG0121	glutamine amidotransferase
WP7W18E02_28100	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
WP7W18E02_28110	COG1960	acyl-CoA dehydrogenase activity
WP7W18E02_28120	COG3437	response regulator, receiver
WP7W18E02_28120	COG0784	Response regulator, receiver
WP7W18E02_28140	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
WP7W18E02_28150	COG0328	RNA-DNA hybrid ribonuclease activity
WP7W18E02_28160	COG2226	methyltransferase
WP7W18E02_28170	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
WP7W18E02_28180	COG1388	LysM domain
WP7W18E02_28180	COG0741	lytic transglycosylase activity
WP7W18E02_28210	COG1607	acyl-coa hydrolase
WP7W18E02_28240	COG0741	lytic transglycosylase activity
WP7W18E02_28260	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
WP7W18E02_28290	COG0729	surface antigen
WP7W18E02_28310	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
WP7W18E02_28330	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
WP7W18E02_28350	COG4134	Bacterial extracellular solute-binding protein
WP7W18E02_28370	COG4136	ATPase activity
WP7W18E02_28380	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
WP7W18E02_28390	COG2951	lytic endotransglycosylase activity
WP7W18E02_28400	COG1846	Transcriptional regulator
WP7W18E02_28420	COG0033	Phosphoglucomutase
WP7W18E02_28430	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
WP7W18E02_28440	COG0596	Alpha beta hydrolase
WP7W18E02_28470	COG0716	FMN binding
WP7W18E02_28490	COG0735	belongs to the Fur family
WP7W18E02_28500	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
WP7W18E02_28520	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
WP7W18E02_28520	COG1263	PTS System
WP7W18E02_28520	COG2190	(PTS) system
WP7W18E02_28530	COG0363	glucosamine-6-phosphate deaminase activity
WP7W18E02_28540	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
WP7W18E02_28550	COG1940	carbohydrate kinase activity
WP7W18E02_28550	COG1846	Transcriptional regulator
WP7W18E02_28570	COG0217	transcriptional regulatory protein
WP7W18E02_28580	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
WP7W18E02_28590	COG1801	Protein of unknown function DUF72
WP7W18E02_28600	COG4106	trans-aconitate 2-methyltransferase activity
WP7W18E02_28610	COG0500	methyltransferase
WP7W18E02_28650	COG0583	DNA-binding transcription factor activity
WP7W18E02_28660	COG0791	NLP P60 protein
WP7W18E02_28690	COG1309	transcriptional regulator
WP7W18E02_28760	COG0534	Mate efflux family protein
WP7W18E02_28780	COG2841	Protein conserved in bacteria
WP7W18E02_28790	COG0674	pyruvate-flavodoxin oxidoreductase activity
WP7W18E02_28790	COG1013	pyruvate-flavodoxin oxidoreductase activity
WP7W18E02_28790	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
WP7W18E02_28790	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
WP7W18E02_28810	COG0633	Ferredoxin
WP7W18E02_28810	COG3217	Mosc domain protein beta barrel domain protein
WP7W18E02_28810	COG0633	Ferredoxin
WP7W18E02_28810	COG3217	Mosc domain protein beta barrel domain protein
WP7W18E02_28820	COG0501	Belongs to the peptidase M48B family
WP7W18E02_28830	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
WP7W18E02_28840	COG2226	methyltransferase
WP7W18E02_28840	COG1073	alpha beta
WP7W18E02_28850	COG0156	8-amino-7-oxononanoate synthase activity
WP7W18E02_28860	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
WP7W18E02_28910	COG0017	Asparaginyl-tRNA synthetase
WP7W18E02_28920	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
WP7W18E02_28950	COG1393	Belongs to the ArsC family
WP7W18E02_28960	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
WP7W18E02_28970	COG1876	peptidase activity
WP7W18E02_28990	COG3263	regulation of cellular component size
WP7W18E02_29020	COG1280	lysine exporter protein (LysE YggA)
WP7W18E02_29080	COG0564	pseudouridine synthase activity
WP7W18E02_29100	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
WP7W18E02_29110	COG0702	epimerase
WP7W18E02_29130	COG2867	negative regulation of translational initiation
WP7W18E02_29140	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
WP7W18E02_29700	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
WP7W18E02_29770	COG2974	May be involved in recombination
WP7W18E02_29900	COG3153	acetyltransferase
WP7W18E02_29970	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
WP7W18E02_30000	COG0745	RESPONSE REGULATOR receiver
WP7W18E02_30010	COG4988	ABC transporter
WP7W18E02_30020	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
WP7W18E02_30060	COG1720	tRNA m6t6A37 methyltransferase activity
WP7W18E02_30090	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
WP7W18E02_30100	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
WP7W18E02_30110	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
WP7W18E02_30130	COG2190	(PTS) system
WP7W18E02_30140	COG3038	cytochrome b561
WP7W18E02_30160	COG0420	3'-5' exonuclease activity
WP7W18E02_30170	COG0456	acetyltransferase
WP7W18E02_30180	COG2974	May be involved in recombination
WP7W18E02_30220	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
WP7W18E02_30230	COG1396	sequence-specific DNA binding
WP7W18E02_30230	COG1917	Cupin 2, conserved barrel domain protein
WP7W18E02_30270	COG0531	amino acid
WP7W18E02_30290	COG0531	amino acid
WP7W18E02_30310	COG1283	sodium-dependent phosphate transmembrane transporter activity
WP7W18E02_30330	COG3384	dioxygenase
WP7W18E02_30340	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
WP7W18E02_30340	COG2205	protein histidine kinase activity
WP7W18E02_30370	COG0784	Response regulator, receiver
WP7W18E02_30370	COG2205	protein histidine kinase activity
WP7W18E02_30480	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
WP7W18E02_30500	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
WP7W18E02_30530	COG4263	nitrous-oxide reductase activity
WP7W18E02_30540	COG3901	Regulator of nitric oxide reductase transcription
WP7W18E02_30540	COG0348	domain, Protein
WP7W18E02_30560	COG1388	LysM domain
WP7W18E02_30560	COG1376	ErfK ybiS ycfS ynhG family protein
WP7W18E02_30590	COG3129	Specifically methylates the adenine in position 1618 of 23S rRNA
WP7W18E02_30600	COG0791	NLP P60 protein
WP7W18E02_30620	COG3118	belongs to the thioredoxin family
WP7W18E02_30630	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
WP7W18E02_30640	COG0788	formyltetrahydrofolate deformylase activity
WP7W18E02_30690	COG0739	heme binding
WP7W18E02_30690	COG0741	lytic transglycosylase activity
WP7W18E02_30690	COG1196	nuclear chromosome segregation
WP7W18E02_30700	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
WP7W18E02_30710	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
WP7W18E02_30720	COG0673	inositol 2-dehydrogenase activity
WP7W18E02_30760	COG1032	radical SAM domain protein
WP7W18E02_30770	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
WP7W18E02_30790	COG3706	GGDEF domain
WP7W18E02_30800	COG1752	Esterase of the alpha-beta hydrolase superfamily
WP7W18E02_30810	COG0733	neurotransmitter:sodium symporter activity
WP7W18E02_30870	COG0281	malic enzyme
WP7W18E02_30890	COG0534	Mate efflux family protein
WP7W18E02_30920	COG2233	PERMEase
WP7W18E02_30930	COG0095	Lipoate-protein ligase
WP7W18E02_30940	COG1115	amino acid carrier protein
WP7W18E02_30960	COG0019	diaminopimelate decarboxylase activity
WP7W18E02_30980	COG0678	peroxiredoxin activity
WP7W18E02_30990	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
WP7W18E02_31010	COG1126	abc transporter atp-binding protein
WP7W18E02_31020	COG0765	amino acid transport
WP7W18E02_31030	COG4597	amino acid ABC transporter
WP7W18E02_31040	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
WP7W18E02_31080	COG0545	Peptidyl-prolyl cis-trans isomerase
WP7W18E02_31100	COG1940	carbohydrate kinase activity
WP7W18E02_31120	COG4783	chaperone-mediated protein folding
WP7W18E02_31140	COG5002	protein histidine kinase activity
WP7W18E02_31150	COG0745	RESPONSE REGULATOR receiver
WP7W18E02_31160	COG0346	lactoylglutathione lyase activity
WP7W18E02_31170	COG3706	GGDEF domain
WP7W18E02_31180	COG3284	Transcriptional regulator
WP7W18E02_31190	COG1012	belongs to the aldehyde dehydrogenase family
WP7W18E02_31210	COG0697	spore germination
WP7W18E02_31230	COG3290	protein histidine kinase activity
WP7W18E02_31240	COG0281	malic enzyme
WP7W18E02_31270	COG1566	PFAM secretion protein HlyD family protein
WP7W18E02_31320	COG0602	queuosine metabolic process
WP7W18E02_31330	COG1328	CTP reductase activity
WP7W18E02_31350	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
WP7W18E02_31360	COG3115	cell septum assembly
WP7W18E02_31370	COG1196	nuclear chromosome segregation
WP7W18E02_31390	COG2860	membrane
WP7W18E02_31410	COG3108	Peptidase M15
WP7W18E02_31420	COG2989	Protein conserved in bacteria
WP7W18E02_31450	COG0463	Glycosyl transferase, family 2
WP7W18E02_31480	COG0366	Alpha amylase catalytic
WP7W18E02_31550	COG3706	GGDEF domain
WP7W18E02_31560	COG0037	tRNA processing
WP7W18E02_31570	COG3590	peptidase
WP7W18E02_31610	COG0531	amino acid
WP7W18E02_31620	COG0814	amino acid
WP7W18E02_31630	COG0583	DNA-binding transcription factor activity
WP7W18E02_31650	COG0825	malonyl-CoA metabolic process
WP7W18E02_31670	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
WP7W18E02_31680	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
WP7W18E02_31690	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
WP7W18E02_31700	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
WP7W18E02_31710	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
WP7W18E02_31740	COG0750	zinc metalloprotease
WP7W18E02_31750	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
WP7W18E02_31760	COG0575	Belongs to the CDS family
WP7W18E02_31770	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
WP7W18E02_31780	COG0233	cytoplasmic translational termination
WP7W18E02_31790	COG0528	UMP kinase activity
WP7W18E02_31800	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
WP7W18E02_31810	COG0052	Belongs to the universal ribosomal protein uS2 family
WP7W18E02_31820	COG0024	Methionine aminopeptidase
WP7W18E02_31830	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
WP7W18E02_31840	COG2171	N-acyltransferase activity
WP7W18E02_31860	COG1263	PTS System
WP7W18E02_31860	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
WP7W18E02_31880	COG4580	involved in the transport of maltose and maltodextrins
WP7W18E02_31900	COG0564	pseudouridine synthase activity
WP7W18E02_31910	COG3098	single-species biofilm formation
WP7W18E02_31960	COG5595	Zn-ribbon-containing, possibly nucleic-acid-binding protein (DUF2310)
WP7W18E02_31980	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
WP7W18E02_31980	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
WP7W18E02_32000	COG3706	GGDEF domain
WP7W18E02_32010	COG1611	Belongs to the LOG family
WP7W18E02_32020	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
WP7W18E02_32030	COG0473	3-isopropylmalate dehydrogenase activity
WP7W18E02_32050	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
WP7W18E02_32060	COG2363	Small membrane protein
WP7W18E02_32080	COG0583	DNA-binding transcription factor activity
WP7W18E02_32090	COG0840	transmembrane signaling receptor activity
WP7W18E02_32100	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
WP7W18E02_32130	COG1477	protein flavinylation
WP7W18E02_32140	COG2871	sodium ion transport
WP7W18E02_32150	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
WP7W18E02_32160	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
WP7W18E02_32170	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
WP7W18E02_32180	COG1805	sodium ion transport
WP7W18E02_32190	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
WP7W18E02_32200	COG0271	Belongs to the BolA IbaG family
WP7W18E02_32210	COG2813	Specifically methylates the guanine in position
WP7W18E02_32230	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
WP7W18E02_32250	COG2211	Major facilitator Superfamily
WP7W18E02_32260	COG3248	Nucleoside-binding outer membrane protein
WP7W18E02_32270	COG1666	GTP binding
WP7W18E02_32340	COG0659	secondary active sulfate transmembrane transporter activity
WP7W18E02_32390	COG1393	Belongs to the ArsC family
WP7W18E02_32400	COG0798	PFAM Bile acid sodium symporter
WP7W18E02_32420	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
WP7W18E02_32460	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
WP7W18E02_32470	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
WP7W18E02_32480	COG1151	hydroxylamine reductase activity
WP7W18E02_32490	COG0783	Belongs to the Dps family
WP7W18E02_32540	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
WP7W18E02_32570	COG0300	oxidoreductase activity
WP7W18E02_32600	COG0789	Transcriptional regulator
WP7W18E02_32610	COG3272	Protein of unknown function (DUF1722)
WP7W18E02_32660	COG0077	Prephenate dehydratase
WP7W18E02_32660	COG1605	Chorismate mutase
WP7W18E02_32700	COG4580	involved in the transport of maltose and maltodextrins
WP7W18E02_32710	COG3940	Belongs to the glycosyl hydrolase 43 family
WP7W18E02_32740	COG1175	transmembrane transport
WP7W18E02_32800	COG2133	pyrroloquinoline quinone binding
WP7W18E02_32820	COG1349	DNA-binding transcription factor activity
WP7W18E02_32830	COG2084	Dehydrogenase
WP7W18E02_32840	COG3395	kinase activity
WP7W18E02_32850	COG0235	Class ii aldolase
WP7W18E02_32860	COG3622	Belongs to the hyi family
WP7W18E02_32870	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
WP7W18E02_32880	COG2610	gluconate transmembrane transporter activity
WP7W18E02_32920	COG0300	oxidoreductase activity
WP7W18E02_32970	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
WP7W18E02_33010	COG3813	Protein conserved in bacteria
WP7W18E02_33030	COG0826	peptidase U32
WP7W18E02_33040	COG1280	lysine exporter protein (LysE YggA)
WP7W18E02_33080	COG2200	EAL domain
WP7W18E02_33080	COG2203	Gaf domain
WP7W18E02_33080	COG2199	diguanylate cyclase activity
WP7W18E02_33160	COG0114	fumarate hydratase activity
WP7W18E02_33180	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
WP7W18E02_33180	COG0506	proline dehydrogenase activity
WP7W18E02_33180	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
WP7W18E02_33190	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
WP7W18E02_33230	COG0737	Belongs to the 5'-nucleotidase family
WP7W18E02_33280	COG0545	Peptidyl-prolyl cis-trans isomerase
WP7W18E02_33310	COG1047	Peptidyl-prolyl cis-trans
WP7W18E02_33320	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
WP7W18E02_33340	COG0835	chemotaxis
WP7W18E02_33340	COG0784	Response regulator, receiver
WP7W18E02_33350	COG0429	hydrolase of the alpha beta-hydrolase fold
WP7W18E02_33360	COG4251	negative regulation of phosphorylation
WP7W18E02_33360	COG2203	Gaf domain
WP7W18E02_33360	COG3706	GGDEF domain
WP7W18E02_33360	COG5001	Diguanylate cyclase
WP7W18E02_33370	COG3089	Belongs to the UPF0270 family
WP7W18E02_33390	COG3954	Phosphoribulokinase
WP7W18E02_33420	COG1765	OsmC-like protein
WP7W18E02_33510	COG2205	protein histidine kinase activity
WP7W18E02_33520	COG2814	Major facilitator Superfamily
WP7W18E02_33570	COG0748	coenzyme F420 binding
WP7W18E02_33580	COG3721	Heme iron utilization protein
WP7W18E02_33600	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
WP7W18E02_33660	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
WP7W18E02_33680	COG0463	Glycosyl transferase, family 2
WP7W18E02_33690	COG0741	lytic transglycosylase activity
WP7W18E02_33700	COG0488	(ABC) transporter
WP7W18E02_33720	COG2252	PERMEase
WP7W18E02_33730	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
WP7W18E02_33740	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
WP7W18E02_33750	COG3178	'Phosphotransferase
WP7W18E02_33760	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
WP7W18E02_33780	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
WP7W18E02_33790	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
WP7W18E02_33800	COG2967	ApaG domain
WP7W18E02_33810	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
WP7W18E02_33830	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
WP7W18E02_33840	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
WP7W18E02_33860	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
WP7W18E02_33870	COG0211	Belongs to the bacterial ribosomal protein bL27 family
WP7W18E02_33880	COG0261	This protein binds to 23S rRNA in the presence of protein L20
WP7W18E02_33890	COG0142	geranyltranstransferase activity
WP7W18E02_33900	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
WP7W18E02_33910	COG0330	HflC and HflK could
WP7W18E02_33920	COG0330	HflC and HflK could
WP7W18E02_33930	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
WP7W18E02_33940	COG1923	regulation of RNA biosynthetic process
WP7W18E02_33950	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
WP7W18E02_33960	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
WP7W18E02_33980	COG0802	atpase or kinase
WP7W18E02_33990	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
WP7W18E02_33990	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
WP7W18E02_34000	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
WP7W18E02_34000	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
WP7W18E02_34040	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
WP7W18E02_34050	COG2011	ABC-type metal ion transport system permease component
WP7W18E02_34060	COG1464	Belongs to the NlpA lipoprotein family
WP7W18E02_34080	COG0840	transmembrane signaling receptor activity
WP7W18E02_34100	COG0784	Response regulator, receiver
WP7W18E02_34100	COG2205	protein histidine kinase activity
WP7W18E02_34160	COG0232	Belongs to the dGTPase family. Type 2 subfamily
WP7W18E02_34170	COG5002	protein histidine kinase activity
WP7W18E02_34170	COG0784	Response regulator, receiver
WP7W18E02_34170	COG2198	Histidine kinase
WP7W18E02_34240	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
WP7W18E02_34250	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
WP7W18E02_34270	COG2716	regulation of RNA biosynthetic process
WP7W18E02_34280	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
WP7W18E02_34300	COG3013	Belongs to the UPF0304 family
WP7W18E02_34320	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
WP7W18E02_34330	COG0857	belongs to the CobB CobQ family
WP7W18E02_34330	COG0280	phosphate acetyltransferase
WP7W18E02_34340	COG0440	acetolactate synthase activity
WP7W18E02_34350	COG0028	Belongs to the TPP enzyme family
WP7W18E02_34370	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
WP7W18E02_34380	COG0671	phosphoesterase, PA-phosphatase related
WP7W18E02_34400	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
WP7W18E02_34410	COG0473	3-isopropylmalate dehydrogenase activity
WP7W18E02_34420	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
WP7W18E02_34430	COG0066	3-isopropylmalate dehydratase activity
WP7W18E02_34470	COG1178	ABC-type Fe3 transport system permease component
WP7W18E02_34480	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
WP7W18E02_34490	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
WP7W18E02_34530	COG0316	Belongs to the HesB IscA family
WP7W18E02_34550	COG0038	chloride channel
WP7W18E02_34560	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
WP7W18E02_34590	COG0671	phosphoesterase, PA-phosphatase related
WP7W18E02_34610	COG0583	DNA-binding transcription factor activity
WP7W18E02_34620	COG2076	Multidrug Resistance protein
WP7W18E02_34640	COG0346	lactoylglutathione lyase activity
WP7W18E02_34650	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
WP7W18E02_34660	COG1643	Atp-dependent helicase
WP7W18E02_34670	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
WP7W18E02_34680	COG1489	DNA binding
WP7W18E02_34690	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
WP7W18E02_34700	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
WP7W18E02_34710	COG0617	tRNA 3'-terminal CCA addition
WP7W18E02_34730	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
WP7W18E02_34740	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
WP7W18E02_34760	COG0842	Transport permease protein
WP7W18E02_34770	COG1131	(ABC) transporter
WP7W18E02_34800	COG0163	prenyltransferase activity
WP7W18E02_34810	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
WP7W18E02_34820	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
WP7W18E02_34860	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
WP7W18E02_34890	COG1136	(ABC) transporter
WP7W18E02_34970	COG0529	Catalyzes the synthesis of activated sulfate
WP7W18E02_34980	COG0471	metal ion transport
WP7W18E02_34980	COG3273	potassium ion transport
WP7W18E02_34990	COG2895	sulfate adenylyltransferase (ATP) activity
WP7W18E02_35000	COG0175	sulfate reduction
WP7W18E02_35010	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
WP7W18E02_35010	COG1648	precorrin-2 dehydrogenase activity
WP7W18E02_35020	COG0330	HflC and HflK could
WP7W18E02_35030	COG1585	Membrane protein implicated in regulation of membrane protease activity
WP7W18E02_35050	COG0673	inositol 2-dehydrogenase activity
WP7W18E02_35070	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
WP7W18E02_35080	COG0635	Involved in the biosynthesis of porphyrin-containing compound
WP7W18E02_35090	COG3036	rescue of stalled ribosome
WP7W18E02_35120	COG0138	bifunctional purine biosynthesis protein purh
WP7W18E02_35130	COG0151	Belongs to the GarS family
WP7W18E02_35300	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
WP7W18E02_35320	COG1610	YqeY-like protein
WP7W18E02_35330	COG0828	Belongs to the bacterial ribosomal protein bS21 family
WP7W18E02_35340	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
WP7W18E02_35360	COG1388	LysM domain
WP7W18E02_35360	COG4942	peptidase
WP7W18E02_35370	COG1238	metal cluster binding
WP7W18E02_35380	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
WP7W18E02_35390	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
WP7W18E02_35400	COG0585	pseudouridine synthase activity
WP7W18E02_35420	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
WP7W18E02_35430	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
WP7W18E02_35440	COG0148	phosphopyruvate hydratase activity
WP7W18E02_35450	COG0504	CTP synthase activity
WP7W18E02_35460	COG3956	TIGRFAM MazG family protein
WP7W18E02_35470	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
WP7W18E02_35480	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
WP7W18E02_35500	COG4807	Protein conserved in bacteria
WP7W18E02_35510	COG3023	N-Acetylmuramoyl-L-alanine amidase
WP7W18E02_35520	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
WP7W18E02_35530	COG1381	Involved in DNA repair and RecF pathway recombination
WP7W18E02_35550	COG0571	ribonuclease III activity
WP7W18E02_35560	COG0681	Belongs to the peptidase S26 family
WP7W18E02_35570	COG0481	GTPase activity
WP7W18E02_35600	COG3073	An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E
WP7W18E02_35610	COG1595	DNA-templated transcription, initiation
WP7W18E02_35620	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
WP7W18E02_35720	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
WP7W18E02_35730	COG0191	fructose-bisphosphate aldolase activity
WP7W18E02_35740	COG0126	phosphoglycerate kinase activity
WP7W18E02_35750	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
WP7W18E02_35760	COG1940	carbohydrate kinase activity
WP7W18E02_35770	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
WP7W18E02_35790	COG4991	sh3 domain protein
WP7W18E02_35800	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
WP7W18E02_35830	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
WP7W18E02_35860	COG1028	Short-chain dehydrogenase reductase Sdr
WP7W18E02_35880	COG1505	serine-type exopeptidase activity
WP7W18E02_35890	COG3174	membrane
WP7W18E02_35900	COG0110	maltose O-acetyltransferase activity
WP7W18E02_35950	COG0165	Argininosuccinate lyase
WP7W18E02_35960	COG0137	argininosuccinate synthase activity
WP7W18E02_35980	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
WP7W18E02_35990	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
WP7W18E02_36010	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
WP7W18E02_36020	COG3447	MASE1 domain protein
WP7W18E02_36020	COG5002	protein histidine kinase activity
WP7W18E02_36020	COG5001	Diguanylate cyclase
WP7W18E02_36120	COG0583	DNA-binding transcription factor activity
WP7W18E02_36130	COG1380	Effector of murein hydrolase LrgA
WP7W18E02_36140	COG1346	cytolysis
WP7W18E02_36150	COG0460	homoserine dehydrogenase
WP7W18E02_36150	COG0527	aspartate kinase activity
WP7W18E02_36160	COG0626	cystathionine gamma-synthase activity
WP7W18E02_36190	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
WP7W18E02_36200	COG0814	amino acid
WP7W18E02_36210	COG1218	3'(2'),5'-bisphosphate nucleotidase
WP7W18E02_36220	COG0494	nUDIX hydrolase
WP7W18E02_36230	COG1011	Hydrolase
WP7W18E02_36240	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
WP7W18E02_36270	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
WP7W18E02_36290	COG3156	type II secretion system protein K
WP7W18E02_36300	COG4795	General secretion pathway protein
WP7W18E02_36310	COG2165	general secretion pathway protein
WP7W18E02_36330	COG2165	general secretion pathway protein
WP7W18E02_36340	COG1459	type II secretion system
WP7W18E02_36350	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
WP7W18E02_36370	COG3031	protein transport across the cell outer membrane
WP7W18E02_36390	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
WP7W18E02_36400	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
WP7W18E02_36440	COG3133	Outer membrane lipoprotein
WP7W18E02_36460	COG1392	Phosphate transport regulator
WP7W18E02_36470	COG0306	phosphate transporter
WP7W18E02_36480	COG0617	tRNA 3'-terminal CCA addition
WP7W18E02_36490	COG3267	Type II secretory pathway component ExeA
WP7W18E02_36490	COG3409	Peptidoglycan-binding domain 1 protein
WP7W18E02_36510	COG1194	a g-specific adenine glycosylase
WP7W18E02_36520	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
WP7W18E02_36550	COG3240	lipase activity
WP7W18E02_36570	COG3009	Protein conserved in bacteria
WP7W18E02_36580	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
WP7W18E02_36580	COG3008	intermembrane lipid transfer
WP7W18E02_36590	COG2995	paraquat-inducible protein a
WP7W18E02_36610	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
WP7W18E02_36620	COG4251	negative regulation of phosphorylation
WP7W18E02_36620	COG5001	Diguanylate cyclase
WP7W18E02_36620	COG3706	GGDEF domain
WP7W18E02_36620	COG2203	Gaf domain
WP7W18E02_36630	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
WP7W18E02_36640	COG2813	Specifically methylates the guanine in position
WP7W18E02_36650	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
WP7W18E02_36660	COG0297	glycogen (starch) synthase activity
WP7W18E02_36690	COG1757	Na H antiporter
WP7W18E02_36700	COG0583	DNA-binding transcription factor activity
WP7W18E02_36710	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
WP7W18E02_36720	COG3842	ATPase activity
WP7W18E02_36730	COG1176	ABC-type spermidine putrescine transport system, permease component I
WP7W18E02_36740	COG1177	transmembrane transport
WP7W18E02_36750	COG1012	belongs to the aldehyde dehydrogenase family
WP7W18E02_36760	COG0109	protoheme IX farnesyltransferase activity
WP7W18E02_36770	COG1612	heme a metabolic process
WP7W18E02_36820	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
WP7W18E02_36830	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
WP7W18E02_36860	COG1854	S-ribosylhomocysteine lyase activity
WP7W18E02_36890	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
WP7W18E02_36890	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
WP7W18E02_36950	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
WP7W18E02_36960	COG1047	Peptidyl-prolyl cis-trans
WP7W18E02_36970	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
WP7W18E02_36980	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
WP7W18E02_36990	COG0196	riboflavin kinase activity
WP7W18E02_37000	COG0728	peptidoglycan biosynthetic process
WP7W18E02_37010	COG0268	Binds directly to 16S ribosomal RNA
WP7W18E02_37020	COG0640	Transcriptional regulator
WP7W18E02_37030	COG0583	DNA-binding transcription factor activity
WP7W18E02_37050	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
WP7W18E02_37060	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
WP7W18E02_37070	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
WP7W18E02_37090	COG1051	belongs to the nudix hydrolase family
WP7W18E02_37120	COG0335	large ribosomal subunit rRNA binding
WP7W18E02_37130	COG0336	Belongs to the RNA methyltransferase TrmD family
WP7W18E02_37140	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
WP7W18E02_37150	COG0228	four-way junction DNA binding
WP7W18E02_37160	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
WP7W18E02_37170	COG4137	Cytochrome C assembly protein
WP7W18E02_37180	COG4536	flavin adenine dinucleotide binding
WP7W18E02_37200	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
WP7W18E02_37200	COG1017	nitric oxide dioxygenase activity
WP7W18E02_37210	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
WP7W18E02_37220	COG0039	L-malate dehydrogenase activity
WP7W18E02_37230	COG4160	amino acid transport
WP7W18E02_37240	COG4215	(ABC) transporter
WP7W18E02_37250	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
WP7W18E02_37260	COG1126	abc transporter atp-binding protein
WP7W18E02_37270	COG1438	arginine binding
WP7W18E02_37280	COG2837	iron assimilation
WP7W18E02_37290	COG3842	ATPase activity
WP7W18E02_37320	COG0347	Belongs to the P(II) protein family
WP7W18E02_37350	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
WP7W18E02_37360	COG0583	DNA-binding transcription factor activity
WP7W18E02_37390	COG1929	Belongs to the glycerate kinase type-1 family
WP7W18E02_37400	COG2610	gluconate transmembrane transporter activity
WP7W18E02_37410	COG3835	regulator
WP7W18E02_37420	COG3112	Uncharacterised protein family (UPF0231)
WP7W18E02_37460	COG1872	DUF167
WP7W18E02_37470	COG0762	integral membrane protein
WP7W18E02_37480	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
WP7W18E02_37490	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
WP7W18E02_37520	COG3022	response to hydroperoxide
WP7W18E02_37530	COG0513	Belongs to the DEAD box helicase family
WP7W18E02_37540	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
WP7W18E02_37590	COG0735	belongs to the Fur family
WP7W18E02_37600	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
WP7W18E02_37630	COG0776	regulation of translation
WP7W18E02_37640	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
WP7W18E02_37660	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
WP7W18E02_37690	COG0560	Phosphoserine phosphatase
WP7W18E02_37710	COG3064	Membrane
WP7W18E02_37750	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
WP7W18E02_37760	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
WP7W18E02_37770	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
WP7W18E02_37790	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
WP7W18E02_37800	COG0084	hydrolase, TatD family'
WP7W18E02_37840	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
WP7W18E02_37850	COG0004	ammonium transporteR
WP7W18E02_37870	COG0795	lipopolysaccharide-transporting ATPase activity
WP7W18E02_37880	COG0795	lipopolysaccharide-transporting ATPase activity
WP7W18E02_37890	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
WP7W18E02_37900	COG2927	DNA polymerase III (CHI subunit)
WP7W18E02_37920	COG1253	flavin adenine dinucleotide binding
WP7W18E02_37930	COG0586	Pfam SNARE associated Golgi protein
WP7W18E02_37940	COG1686	Belongs to the peptidase S11 family
WP7W18E02_37950	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
WP7W18E02_37960	COG0527	aspartate kinase activity
WP7W18E02_37970	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
WP7W18E02_37990	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
WP7W18E02_38000	COG1546	Belongs to the CinA family
WP7W18E02_38020	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
WP7W18E02_38060	COG3068	Protein conserved in bacteria
WP7W18E02_38080	COG0739	heme binding
WP7W18E02_38120	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
WP7W18E02_38130	COG1121	(ABC) transporter
WP7W18E02_38140	COG1108	ABC-type Mn2 Zn2 transport systems permease components
WP7W18E02_38150	COG0583	DNA-binding transcription factor activity
WP7W18E02_38170	COG1573	uracil-dna glycosylase
WP7W18E02_38190	COG2827	Endonuclease containing a URI domain
WP7W18E02_38220	COG1842	Phage shock protein A
WP7W18E02_38230	COG0204	Acyl-transferase
WP7W18E02_38270	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
WP7W18E02_38290	COG0484	heat shock protein binding
WP7W18E02_38420	COG3039	Transposase
WP7W18E02_38460	COG1051	belongs to the nudix hydrolase family
WP7W18E02_38470	COG3150	esterase
WP7W18E02_38490	COG3151	Protein conserved in bacteria
WP7W18E02_38500	COG0494	nUDIX hydrolase
WP7W18E02_38510	COG1538	Outer membrane efflux protein
WP7W18E02_38520	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
WP7W18E02_38520	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
WP7W18E02_38530	COG1560	Kdo2-lipid A biosynthetic process
WP7W18E02_38570	COG2771	luxR family
WP7W18E02_38600	COG4776	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction
WP7W18E02_38610	COG2213	PTS system mannitol-specific
WP7W18E02_38610	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
WP7W18E02_38620	COG0246	Mannitol dehydrogenase
WP7W18E02_38630	COG3722	fumarate hydratase activity
WP7W18E02_38680	COG1671	Belongs to the UPF0178 family
WP7W18E02_38710	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
WP7W18E02_38720	COG0513	Belongs to the DEAD box helicase family
WP7W18E02_38770	COG1575	Belongs to the MenA family. Type 1 subfamily
WP7W18E02_38780	COG1169	isochorismate synthase
WP7W18E02_38790	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
WP7W18E02_38800	COG0596	Alpha beta hydrolase
WP7W18E02_38810	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
WP7W18E02_38820	COG1441	menaquinone biosynthetic process
WP7W18E02_38830	COG0318	PFAM AMP-dependent synthetase and ligase
WP7W18E02_38840	COG3291	Pkd domain containing protein
WP7W18E02_38850	COG2949	membrane
WP7W18E02_38860	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
WP7W18E02_38880	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
WP7W18E02_38940	COG2873	o-acetylhomoserine
WP7W18E02_38970	COG1979	alcohol dehydrogenase
WP7W18E02_39000	COG4221	oxidoreductase activity
WP7W18E02_39100	COG3047	cAMP biosynthetic process
WP7W18E02_39120	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
WP7W18E02_39130	COG2197	response regulator
WP7W18E02_39200	COG1278	Cold shock
WP7W18E02_39210	COG2205	protein histidine kinase activity
WP7W18E02_39220	COG0745	RESPONSE REGULATOR receiver
WP7W18E02_39260	COG3706	GGDEF domain
WP7W18E02_39270	COG0347	Belongs to the P(II) protein family
WP7W18E02_39280	COG0004	ammonium transporteR
WP7W18E02_39300	COG0346	lactoylglutathione lyase activity
WP7W18E02_39340	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
WP7W18E02_39350	COG1074	ATP-dependent DNA helicase activity
WP7W18E02_39360	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
WP7W18E02_39370	COG2259	Doxx family
WP7W18E02_39380	COG1741	Belongs to the pirin family
WP7W18E02_39400	COG0583	DNA-binding transcription factor activity
WP7W18E02_39450	COG1176	ABC-type spermidine putrescine transport system, permease component I
WP7W18E02_39470	COG3842	ATPase activity
WP7W18E02_39490	COG2199	diguanylate cyclase activity
WP7W18E02_39520	COG2207	Transcriptional regulator
WP7W18E02_39530	COG1247	-acetyltransferase
WP7W18E02_39540	COG0753	catalase activity
WP7W18E02_39590	COG0628	permease
WP7W18E02_39610	COG3284	Transcriptional regulator
WP7W18E02_39620	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
WP7W18E02_39620	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
WP7W18E02_39620	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
WP7W18E02_39630	COG1461	Dihydroxyacetone kinase
WP7W18E02_39640	COG2376	Dihydroxyacetone kinase
WP7W18E02_39650	COG2252	PERMEase
WP7W18E02_39660	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
WP7W18E02_39790	COG1070	Carbohydrate kinase
WP7W18E02_39810	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
WP7W18E02_39830	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
WP7W18E02_39840	COG1879	ABC-type sugar transport system periplasmic component
WP7W18E02_39850	COG1129	ABC transporter
WP7W18E02_39860	COG1172	Belongs to the binding-protein-dependent transport system permease family
WP7W18E02_39870	COG2801	Transposase and inactivated derivatives
WP7W18E02_39940	COG3436	PFAM IS66 Orf2 family protein
WP7W18E02_39950	COG4372	Transposase
WP7W18E02_39960	COG1484	DNA-dependent DNA replication
WP7W18E02_39970	COG4584	PFAM Integrase catalytic
WP7W18E02_39980	COG0203	ribosomal protein L17
WP7W18E02_39990	COG0202	RNA polymerase activity
WP7W18E02_40000	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
WP7W18E02_40010	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
WP7W18E02_40020	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
WP7W18E02_40030	COG0201	protein transport
WP7W18E02_40040	COG0200	Binds to the 23S rRNA
WP7W18E02_40050	COG1841	ribosomal large subunit assembly
WP7W18E02_40060	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
WP7W18E02_40070	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
WP7W18E02_40080	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
WP7W18E02_40090	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
WP7W18E02_40100	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
WP7W18E02_40110	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
WP7W18E02_40120	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
WP7W18E02_40130	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
WP7W18E02_40140	COG0255	Belongs to the universal ribosomal protein uL29 family
WP7W18E02_40150	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
WP7W18E02_40160	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
WP7W18E02_40170	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
WP7W18E02_40180	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
WP7W18E02_40190	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
WP7W18E02_40200	COG0089	rRNA binding
WP7W18E02_40210	COG0088	Forms part of the polypeptide exit tunnel
WP7W18E02_40220	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
WP7W18E02_40230	COG0051	transcription antitermination factor activity, RNA binding
WP7W18E02_40250	COG2205	protein histidine kinase activity
WP7W18E02_40260	COG0745	RESPONSE REGULATOR receiver
WP7W18E02_40270	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
WP7W18E02_40280	COG2183	response to ionizing radiation
WP7W18E02_40310	COG1401	restriction endodeoxyribonuclease activity
WP7W18E02_40310	COG1401	restriction endodeoxyribonuclease activity
WP7W18E02_40320	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
WP7W18E02_40360	COG0582	viral genome integration into host DNA
WP7W18E02_40400	COG0596	Alpha beta hydrolase
WP7W18E02_40410	COG1040	competence protein
WP7W18E02_40420	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
WP7W18E02_40420	COG0316	Belongs to the HesB IscA family
WP7W18E02_40430	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
WP7W18E02_40440	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
WP7W18E02_40450	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
WP7W18E02_40460	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
WP7W18E02_40470	COG4942	peptidase
WP7W18E02_40490	COG1609	Transcriptional regulator
WP7W18E02_40500	COG0800	Aldolase
WP7W18E02_40510	COG0129	dihydroxy-acid dehydratase activity
WP7W18E02_40520	COG3265	gluconokinase activity
WP7W18E02_40530	COG2610	gluconate transmembrane transporter activity
WP7W18E02_40540	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
WP7W18E02_40550	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
WP7W18E02_40570	COG0456	acetyltransferase
WP7W18E02_40600	COG1490	D-aminoacyl-tRNA deacylase activity
WP7W18E02_40610	COG1295	ribonuclease BN
WP7W18E02_40630	COG0174	glutamine synthetase
WP7W18E02_40650	COG3852	Histidine kinase
WP7W18E02_40670	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
WP7W18E02_40680	COG0635	Involved in the biosynthesis of porphyrin-containing compound
WP7W18E02_40700	COG3078	GTPase activator activity
WP7W18E02_40720	COG0218	Necessary for normal cell division and for the maintenance of normal septation
WP7W18E02_40730	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
WP7W18E02_40740	COG0408	coproporphyrinogen oxidase activity
WP7W18E02_40750	COG0009	L-threonylcarbamoyladenylate synthase
WP7W18E02_40760	COG0551	DNA topoisomerase type I activity
WP7W18E02_40770	COG2922	Belongs to the Smg family
WP7W18E02_40780	COG0758	DNA mediated transformation
WP7W18E02_40800	COG0242	peptide deformylase activity
WP7W18E02_40810	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
WP7W18E02_40820	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
WP7W18E02_40820	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
WP7W18E02_40830	COG0569	domain protein
WP7W18E02_40840	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
WP7W18E02_40850	COG1322	Protein conserved in bacteria
WP7W18E02_40890	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
WP7W18E02_40910	COG0519	Catalyzes the synthesis of GMP from XMP
WP7W18E02_40910	COG0518	GMP synthase (glutamine-hydrolyzing) activity
WP7W18E02_40940	COG1396	sequence-specific DNA binding
WP7W18E02_40950	COG1012	belongs to the aldehyde dehydrogenase family
WP7W18E02_40970	COG2962	Rard protein
WP7W18E02_40990	COG1280	lysine exporter protein (LysE YggA)
WP7W18E02_41000	COG2391	methyltransferase activity
WP7W18E02_41070	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
WP7W18E02_41120	COG0210	DNA helicase
WP7W18E02_41180	COG0583	DNA-binding transcription factor activity
WP7W18E02_41220	COG1262	PFAM Formylglycine-generating sulfatase enzyme
WP7W18E02_41230	COG0385	Bile acid
WP7W18E02_41240	COG0531	amino acid
WP7W18E02_41250	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
WP7W18E02_41260	COG0531	amino acid
WP7W18E02_41270	COG2731	YhcH YjgK YiaL family protein
WP7W18E02_41280	COG3250	beta-galactosidase activity
WP7W18E02_41290	COG1609	Transcriptional regulator
WP7W18E02_41300	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
WP7W18E02_41310	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
WP7W18E02_41310	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
WP7W18E02_41320	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
WP7W18E02_41330	COG3074	FtsZ-dependent cytokinesis
WP7W18E02_41350	COG1045	serine acetyltransferase
WP7W18E02_41370	COG0745	RESPONSE REGULATOR receiver
WP7W18E02_41380	COG2205	protein histidine kinase activity
WP7W18E02_41390	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
WP7W18E02_41400	COG0534	Mate efflux family protein
WP7W18E02_41430	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
WP7W18E02_41440	COG2937	Belongs to the GPAT DAPAT family
WP7W18E02_41450	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
WP7W18E02_41460	COG3161	chorismate lyase activity
WP7W18E02_41470	COG1580	Controls the rotational direction of flagella during chemotaxis
WP7W18E02_41510	COG0604	alcohol dehydrogenase
WP7W18E02_41520	COG1609	Transcriptional regulator
WP7W18E02_41620	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
WP7W18E02_41650	COG1063	alcohol dehydrogenase
WP7W18E02_41670	COG5001	Diguanylate cyclase
WP7W18E02_41670	COG3300	MHYT domain
WP7W18E02_41680	COG0210	DNA helicase
WP7W18E02_41690	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
WP7W18E02_41700	COG2166	iron-sulfur cluster assembly
WP7W18E02_41710	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
WP7W18E02_41730	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
WP7W18E02_41740	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
WP7W18E02_41750	COG1739	Uncharacterized protein family UPF0029
WP7W18E02_41760	COG0006	proline dipeptidase activity
WP7W18E02_41770	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
WP7W18E02_41780	COG1024	Enoyl-CoA hydratase
WP7W18E02_41780	COG1250	3-hydroxyacyl-CoA dehydrogenase
WP7W18E02_41790	COG0183	Belongs to the thiolase family
WP7W18E02_41800	COG0745	RESPONSE REGULATOR receiver
WP7W18E02_41820	COG1653	transport
WP7W18E02_41840	COG0425	Belongs to the sulfur carrier protein TusA family
WP7W18E02_41850	COG0251	oxidation-reduction process
WP7W18E02_41860	COG2885	chlorophyll binding
WP7W18E02_41910	COG2818	Glycosylase
WP7W18E02_41920	COG0752	glycyl-tRNA synthetase alpha subunit
WP7W18E02_41930	COG0751	glycine-tRNA ligase activity
WP7W18E02_41980	COG0814	amino acid
WP7W18E02_41990	COG0814	amino acid
WP7W18E02_42000	COG3033	Beta-eliminating lyase
WP7W18E02_42020	COG0348	domain, Protein
WP7W18E02_42040	COG0446	pyridine nucleotide-disulphide oxidoreductase
WP7W18E02_42050	COG0426	domain, Protein
WP7W18E02_42050	COG1773	rubredoxin
WP7W18E02_42060	COG3604	Transcriptional regulator
WP7W18E02_42070	COG1609	Transcriptional regulator
WP7W18E02_42150	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
WP7W18E02_42180	COG2960	long-chain fatty acid transporting porin activity
WP7W18E02_42200	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
WP7W18E02_42230	COG3118	belongs to the thioredoxin family
WP7W18E02_42240	COG0513	Belongs to the DEAD box helicase family
WP7W18E02_42250	COG0248	Ppx GppA phosphatase
WP7W18E02_42280	COG0742	ribosomal rna small subunit methyltransferase
WP7W18E02_42320	COG0084	hydrolase, TatD family'
WP7W18E02_42330	COG0805	protein transport
WP7W18E02_42340	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
WP7W18E02_42350	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
WP7W18E02_42360	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
WP7W18E02_42370	COG3165	ubiquinone biosynthetic process from chorismate
WP7W18E02_42380	COG2226	methyltransferase
WP7W18E02_42390	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
WP7W18E02_42400	COG0402	S-adenosylhomocysteine deaminase activity
WP7W18E02_42410	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
WP7W18E02_42440	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
WP7W18E02_42450	COG0848	biopolymer transport protein
WP7W18E02_42460	COG0811	peptide transport
WP7W18E02_42470	COG0811	peptide transport
WP7W18E02_42490	COG2771	luxR family
WP7W18E02_42500	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
WP7W18E02_42510	COG1349	DNA-binding transcription factor activity
WP7W18E02_42520	COG0745	RESPONSE REGULATOR receiver
WP7W18E02_42530	COG2205	protein histidine kinase activity
WP7W18E02_42550	COG4452	Inner membrane protein CreD
WP7W18E02_42560	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
WP7W18E02_42570	COG0355	proton-transporting ATP synthase activity, rotational mechanism
WP7W18E02_42580	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
WP7W18E02_42590	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
WP7W18E02_42600	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
WP7W18E02_42610	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
WP7W18E02_42620	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
WP7W18E02_42640	COG0356	it plays a direct role in the translocation of protons across the membrane
WP7W18E02_42660	COG1475	DNA binding
WP7W18E02_42670	COG1192	Involved in chromosome partitioning
WP7W18E02_42680	COG0357	Ribosomal RNA small subunit methyltransferase G
WP7W18E02_42690	COG0445	tRNA wobble uridine modification
WP7W18E02_42700	COG0716	FMN binding
WP7W18E02_42710	COG4774	siderophore transport
WP7W18E02_42720	COG4615	Cyclic peptide transporter
WP7W18E02_42730	COG1120	ATPase activity
WP7W18E02_42740	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
WP7W18E02_42750	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
WP7W18E02_42760	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
WP7W18E02_42770	COG0706	membrane insertase activity
WP7W18E02_42780	COG0594	ribonuclease P activity
WP7W18E02_42790	COG0230	Belongs to the bacterial ribosomal protein bL34 family