locus-tag	class	description
B224_0003	ENOG4105CVG	Homoserine O-transsuccinylase
B224_0005	ENOG4108YXU	transcriptional regulator AsnC family
B224_0007	ENOG4105DKK	Benzoate
B224_0008	ENOG4108JCI	Transcriptional regulator
B224_0011	ENOG41090HJ	UPF0265 protein
B224_0014	ENOG4105N42	UPF0307 protein
B224_0015	ENOG4105CMS	peptidase U62, modulator of DNA gyrase
B224_0016	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
B224_0017	ENOG4105VFK	BolA family
B224_0020	ENOG4105E3I	toluene tolerance
B224_0023	ENOG4107PE3	Mammalian cell entry related domain protein
B224_0024	ENOG4105CY3	ABC transporter, permease
B224_0025	ENOG4105DHJ	ABC, transporter
B224_0026	ENOG4105C2X	Arabinose 5-phosphate isomerase
B224_0027	ENOG4108Z4R	3-deoxy-d-manno-octulosonate 8-phosphate phosphatase
B224_0028	ENOG4108P1K	Required for the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane (By similarity)
B224_0029	ENOG4105WI0	lipopolysaccharide transport periplasmic protein lptA
B224_0030	ENOG4108IUZ	ABC transporter
B224_0032	ENOG4105DTW	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
B224_0033	ENOG41080QH	sigma 54 modulation protein ribosomal protein S30EA
B224_0034	ENOG4107RM2	PTS IIA-like nitrogen-regulatory protein PtsN
B224_0035	ENOG4105C21	Displays ATPase and GTPase activities (By similarity)
B224_0036	ENOG41080Z8	PHOSPHOCARRIER protein
B224_0043	ENOG4105C0H	protease
B224_0044	ENOG4105C0H	protease
B224_0046	ENOG4105D6Z	AFG1 family ATPase
B224_0047	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
B224_0048	ENOG4108UJD	30S ribosomal protein S9
B224_0049	ENOG4108R5F	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
B224_0050	ENOG4105DJ5	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
B224_0053	ENOG4105EIX	cytochrome c1
B224_0054	ENOG4107MKT	Stringent starvation protein a
B224_0055	ENOG4105KB2	stringent starvation protein b
B224_0056	ENOG4105W4M	Transport-associated protein
B224_0057	ENOG4105F55	Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate (By similarity)
B224_0059	ENOG41082RQ	UPF0102 protein
B224_0061	ENOG4105E1C	Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1A (PBP1a) (By similarity)
B224_0062	ENOG4105CU0	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity)
B224_0069	ENOG410600T	transposase
B224_0078	ENOG4108V6E	Cell division protein mraZ
B224_0079	ENOG4105CGJ	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity)
B224_0080	ENOG41063Y6	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity)
B224_0083	ENOG4105CJN	penicillin-binding protein
B224_0086	ENOG4107EEN	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity)
B224_0087	ENOG4108EQQ	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein (By similarity)
B224_0088	ENOG4105CPY	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity)
B224_0091	ENOG4105DMZ	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity)
B224_0093	ENOG4105CNI	cell division protein FtsW
B224_0094	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
B224_0096	ENOG4105DFU	Cell wall formation (By similarity)
B224_0098	ENOG4105K7E	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly (By similarity)
B224_0099	ENOG4105CIT	This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity)
B224_0101	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
B224_0102	ENOG4105C7C	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
B224_0104	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
B224_0107	ENOG41067SF	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase (By similarity)
B224_0108	ENOG4105DHA	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity (By similarity)
B224_0111	ENOG4105EHH	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue (By similarity)
B224_0112	ENOG4105D7Q	type ii secretion system
B224_0113	ENOG4107QHF	type ii secretion system protein e
B224_0114	ENOG410600T	transposase
B224_0116	ENOG4105D18	nicotinate-nucleotide pyrophosphorylase
B224_0120	ENOG41073TP	transcriptional regulator
B224_0121	ENOG4105DAQ	Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) (By similarity)
B224_0122	ENOG4107QSN	dihydrolipoamide acetyltransferase
B224_0125	ENOG4107QN2	dihydrolipoyl dehydrogenase
B224_0126	ENOG4105BZU	Histidine kinase
B224_0130	ENOG41069D7	Methyl-accepting chemotaxis
B224_0131	ENOG4105D78	K07001 NTE family protein
B224_0132	ENOG4107QIJ	Aconitate hydratase 2
B224_0134	ENOG4105BZU	Histidine kinase
B224_0135	ENOG4108MGI	Transcriptional regulator
B224_0136	ENOG4105E82	cytochrome subunit of dehydrogenase
B224_0140	ENOG4105CKI	cobalamin synthesis protein
B224_0144	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
B224_0147	ENOG4105K8U	2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
B224_0148	ENOG4107ZVW	dihydroneopterin aldolase
B224_0149	ENOG4105K7Z	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP (By similarity)
B224_0151	ENOG4105UYK	outer membrane protein a
B224_0166	ENOG4107AQZ	Membrane
B224_0168	ENOG410600T	transposase
B224_0169	ENOG4108UW5	maltose o-acetyltransferase
B224_0172	ENOG4105CG3	alpha amylase, catalytic region
B224_0174	ENOG4105C5Y	PTS System
B224_0176	ENOG4105D4X	repressor
B224_0178	ENOG4105CK1	PTS System
B224_0179	ENOG4105VZJ	PTS System
B224_0180	ENOG4105CK1	PTS System
B224_0181	ENOG4105CS2	ec 3.2.1.21
B224_0183	ENOG4105VCP	PTS System
B224_0185	ENOG4105DKQ	ROK family
B224_0190	ENOG4105DDV	Transcriptional regulator (LacI family
B224_0193	ENOG4105HDK	L-asparaginase
B224_0194	ENOG410600T	transposase
B224_0199	ENOG4108Z5K	methylglyoxal synthase
B224_0200	ENOG4108UQY	Iron-storage protein
B224_0205	ENOG4105E0I	Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of tRNA(Met), by using acetyl-CoA as an acetyl donor and ATP (or GTP) (By similarity)
B224_0207	ENOG4105BZ9	Cytochrome C oxidase, subunit I
B224_0208	ENOG4105FT1	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I (By similarity)
B224_0209	ENOG4107QS1	Cytochrome C Oxidase, Subunit III
B224_0214	ENOG4107VFP	cytochrome oxidase assembly
B224_0215	ENOG4105F1R	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group (By similarity)
B224_0217	ENOG4105C26	Dehydrogenase
B224_0218	ENOG4105NRK	Binding-protein-dependent transport systems, inner membrane component
B224_0219	ENOG4105D81	ABC transporter, permease
B224_0220	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
B224_0222	ENOG4107TYH	extracellular solute-binding protein family 1
B224_0224	ENOG4108M0I	Transcriptional regulator
B224_0226	ENOG4105DFD	Na H antiporter
B224_0229	ENOG4105CXW	Synthesizes alpha-1,4-glucan chains using ADP-glucose (By similarity)
B224_0231	ENOG4107QQ4	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans (By similarity)
B224_0232	ENOG4105D8J	Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle (By similarity)
B224_0233	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
B224_0236	ENOG4107VXZ	Hydrolase
B224_0237	ENOG4105KW8	RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity)
B224_0238	ENOG4105F1S	paraquat-inducible protein a
B224_0240	ENOG4105DY2	Paraquat-inducible protein b
B224_0241	ENOG4108Q2G	(LipO)protein
B224_0242	ENOG4105UYK	outer membrane protein a
B224_0247	ENOG4105KMG	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes (By similarity)
B224_0248	ENOG4105CEN	a g-specific adenine glycosylase
B224_0253	ENOG4105D4J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
B224_0255	ENOG4105CJ3	phosphate transporter
B224_0256	ENOG4107IX6	phosphate transport regulator
B224_0260	ENOG4108XTF	Outer Membrane Lipoprotein
B224_0266	ENOG4105DJ1	Phosphoenolpyruvate Carboxylase
B224_0267	ENOG4105F4C	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress (By similarity)
B224_0269	ENOG4105VEJ	Heat shock protein
B224_0272	ENOG4105GVR	general secretion pathway protein D
B224_0274	ENOG4107QHF	type ii secretion system protein e
B224_0275	ENOG4105D7Q	type ii secretion system
B224_0276	ENOG4108VAU	general secretion pathway protein G
B224_0289	ENOG4108UDW	Transcriptional regulator, luxr family
B224_0290	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
B224_0293	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
B224_0295	ENOG4107Y3D	HAD-superfamily hydrolase subfamily IA variant 3
B224_0296	ENOG4107RK2	ADP-ribose diphosphatase NudE
B224_0297	ENOG4108RNI	3'(2')5'-bisphosphate nucleotidase
B224_0298	ENOG4105C44	Serine transporter
B224_0300	ENOG4108Z7R	Chaperone CsaA
B224_0303	ENOG4105GGQ	This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis (By similarity)
B224_0304	ENOG4105C28	cystathionine
B224_0306	ENOG4105CFH	Aspartokinase
B224_0308	ENOG41067MG	lrgb family
B224_0310	ENOG4105CMU	LysR family (Transcriptional regulator
B224_0318	ENOG4108Z66	YbaK ebsC protein
B224_0320	ENOG4105BZU	Histidine kinase
B224_0323	ENOG4105CCA	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle (By similarity)
B224_0326	ENOG4105C0N	N-acetylglutamate semialdehyde dehydrogenase
B224_0327	ENOG4105CAS	nag kinase
B224_0330	ENOG4105CDH	Citrulline--aspartate ligase
B224_0332	ENOG4105CH7	arginosuccinase
B224_0335	ENOG4105F2I	Transposase
B224_0342	ENOG4108UW5	maltose o-acetyltransferase
B224_0344	ENOG4107PU6	Membrane
B224_0349	ENOG4105CYX	Short-chain dehydrogenase reductase Sdr
B224_0352	ENOG4105CE6	Adenylation and deadenylation of glutamate--ammonia ligase (By similarity)
B224_0354	ENOG4108NVR	Methyl-accepting chemotaxis
B224_0356	ENOG4105EYW	Ion transport protein
B224_0357	ENOG4106MWK	domain protein
B224_0358	ENOG4105E09	nadh pyrophosphatase
B224_0359	ENOG4105CFZ	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III (By similarity)
B224_0361	ENOG4105DKQ	ROK family
B224_0362	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
B224_0363	ENOG4105BZA	Phosphoglycerate kinase
B224_0365	ENOG4105D2N	Aldolase
B224_0366	ENOG4105CJP	fad dependent oxidoreductase
B224_0368	ENOG4105CSG	Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps (By similarity)
B224_0369	ENOG4105VF7	tolerance protein
B224_0376	ENOG4105Y75	tpr repeat protein
B224_0379	ENOG4108IYU	L-aspartate oxidase
B224_0380	ENOG4105EMN	RNA polymerase sigma factor
B224_0385	ENOG4105C4S	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity)
B224_0387	ENOG4105C3F	Signal peptidase i
B224_0390	ENOG41071DT	Involved in DNA repair and RecF pathway recombination (By similarity)
B224_0391	ENOG4105CSZ	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate (By similarity)
B224_0392	ENOG4108VBV	N-Acetylmuramoyl-L-alanine amidase
B224_0393	ENOG4108W15	Protein of unknown function (DUF1456)
B224_0394	ENOG4105BZU	Histidine kinase
B224_0396	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
B224_0399	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
B224_0401	ENOG4105DXN	mazG family
B224_0403	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
B224_0405	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
B224_0407	ENOG4105XX3	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity)
B224_0408	ENOG4105CE5	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) (By similarity)
B224_0409	ENOG4108UH8	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (By similarity)
B224_0411	ENOG4106NZV	Responsible for synthesis of pseudouridine from uracil- 13 in transfer RNAs (By similarity)
B224_0412	ENOG4105CV2	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates (By similarity)
B224_0413	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
B224_0414	ENOG4108UM1	dedA family
B224_0415	ENOG4108K5P	(LipO)protein
B224_0416	ENOG4105F2I	Transposase
B224_0418	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
B224_0419	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
B224_0420	ENOG4105VCC	30S ribosomal protein S21
B224_0421	ENOG4105KTH	gatB Yqey
B224_0423	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
B224_0424	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
B224_0432	ENOG4105C12	Phosphoribosylglycinamide synthetase
B224_0434	ENOG4105DC1	bifunctional purine biosynthesis protein purh
B224_0440	ENOG4105CSA	Coproporphyrinogen iii oxidase
B224_0441	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
B224_0443	ENOG4105CNH	Multidrug resistance protein MdtL
B224_0445	ENOG4105D9R	oxidoreductase
B224_0448	ENOG4105G5H	Membrane
B224_0449	ENOG4107QX8	SPFH domain, Band 7 family protein
B224_0450	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
B224_0452	ENOG4105C11	sulfate adenylyltransferase), subunit 2
B224_0454	ENOG4105C3T	may be the GTPase, regulating ATP sulfurylase activity (By similarity)
B224_0457	ENOG4108I67	Catalyzes the synthesis of activated sulfate (By similarity)
B224_0458	ENOG4105F2I	Transposase
B224_0460	ENOG4105F2I	Transposase
B224_0463	ENOG4107RHT	methyl-accepting chemotaxis sensory transducer with Pas Pac sensor
B224_0472	ENOG4108UUE	Transcriptional regulator
B224_0475	ENOG4105F0N	pyrophosphate phospho-hydrolase
B224_0476	ENOG4105DFU	Cell wall formation (By similarity)
B224_0477	ENOG4108UMA	3-octaprenyl-4-hydroxybenzoate carboxy-lyase
B224_0479	ENOG410630P	Transcriptional regulator
B224_0480	ENOG4108UGV	hypoxanthine phosphoribosyltransferase
B224_0481	ENOG4105DA5	(ABC) transporter
B224_0482	ENOG4105E3A	(ABC) transporter
B224_0485	ENOG4108IAA	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate (By similarity)
B224_0486	ENOG4105CCG	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is tranferred onto alpha-ketoisovalerate to form ketopantoate (By similarity)
B224_0487	ENOG4105K8U	2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
B224_0489	ENOG4105DJ0	Poly(A) Polymerase
B224_0491	ENOG4106F3G	Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon (By similarity)
B224_0492	ENOG4108V7X	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
B224_0497	ENOG4105PW4	Sugar fermentation stimulation protein homolog
B224_0498	ENOG4108784	2'-5' rna ligase
B224_0499	ENOG4105CQ7	ATP-dependent helicase
B224_0501	ENOG4105BZ4	penicillin-binding protein
B224_0502	ENOG4108YZK	glyoxalase bleomycin resistance protein dioxygenase
B224_0504	ENOG4108ZBZ	Catalyzes the excretion of spermidine (By similarity)
B224_0506	ENOG41090TI	Catalyzes the excretion of spermidine (By similarity)
B224_0507	ENOG4105EGI	Transcriptional regulator
B224_0509	ENOG41076MN	Phosphoesterase, PA-phosphatase related
B224_0513	ENOG4105CDM	Glutamate-1-semialdehyde aminotransferase
B224_0515	ENOG4105CMQ	Chloride channel
B224_0518	ENOG4108YX9	iron--sulfur cluster insertion protein erpA
B224_0521	ENOG4108NIW	Leucine export protein LeuE
B224_0522	ENOG4105VY0	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters (By similarity)
B224_0523	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
B224_0526	ENOG4107V40	secretion protein, HlyD family
B224_0536	ENOG4105I93	response regulator
B224_0538	ENOG4105DUX	Transporter
B224_0539	ENOG4105C3Y	UTP-glucose-1-phosphate uridylyltransferase
B224_0540	ENOG41083P1	competence protein ComEA helix-hairpin-helix repeat protein
B224_0541	ENOG4108RNI	3'(2')5'-bisphosphate nucleotidase
B224_0542	ENOG4105K9H	YciI-like protein
B224_0544	ENOG4107835	probably involved in intracellular septation (By similarity)
B224_0545	ENOG4105DY8	decarboxylase
B224_0547	ENOG4108UT2	hemolysin iii
B224_0549	ENOG4105D0C	transport protein
B224_0556	ENOG4105F2I	Transposase
B224_0557	ENOG410600T	transposase
B224_0561	ENOG4105CK7	Sodium proline symporter
B224_0563	ENOG4107N1Q	ErfK YbiS YcfS YnhG family protein
B224_0565	ENOG4105CUY	Mechanosensitive ion channel
B224_0568	ENOG4105XEP	YhcH YjgK YiaL family protein
B224_0571	ENOG4105D9U	N-acetyltransferase
B224_0577	ENOG410600T	transposase
B224_0580	ENOG4105EV4	Multidrug resistance protein mdtH
B224_0592	ENOG4105D6S	protein involved in catabolism of external DNA
B224_0595	ENOG4105C5H	ABC transporter
B224_0596	ENOG41080XP	Cbs domain
B224_0598	ENOG4105F2I	Transposase
B224_0599	ENOG4105FCK	Membrane
B224_0602	ENOG4108VYJ	response regulator receiver protein
B224_0603	ENOG4108UJV	acyl-CoA thioesterase i
B224_0604	ENOG4108I0Y	(ABC) transporter
B224_0606	ENOG4105CV6	ABC transporter, permease
B224_0607	ENOG4105ECP	epimerase
B224_0610	ENOG4105BZU	Histidine kinase
B224_0613	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
B224_0614	ENOG4105IIU	Aminopeptidase
B224_0616	ENOG4105CZ1	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity)
B224_0617	ENOG41090ED	Protein with unknown function (DUF469)
B224_0619	ENOG4105CSV	Glutaminase
B224_0620	ENOG4107RM6	sulfurtransferase
B224_0623	ENOG4105SUV	lipoprotein YgdR
B224_0625	ENOG4105BZ1	(ABC) transporter
B224_0633	ENOG4105F2I	Transposase
B224_0635	ENOG4105ETE	Transcriptional regulator (LacI family
B224_0636	ENOG4105W3H	MtN3 and saliva related transmembrane protein
B224_0637	ENOG4105ENN	converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose (By similarity)
B224_0638	ENOG4105CRD	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P) (By similarity)
B224_0640	ENOG4105F0Z	galactose-1-phosphate uridylyltransferase
B224_0641	ENOG4105CMR	udp-glucose 4-epimerase
B224_0643	ENOG4107G87	m6 family metalloprotease domain protein
B224_0644	ENOG4105KQT	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome (By similarity)
B224_0651	ENOG4105BZU	Histidine kinase
B224_0658	ENOG4105VYA	Uncharacterized conserved protein (DUF2132)
B224_0659	ENOG4105DJ4	phosphatidylserine decarboxylase
B224_0662	ENOG4108RBP	3'-to-5' exoribonuclease specific for small oligoribonucleotides (By similarity)
B224_0663	ENOG4105VEQ	Cold shock protein
B224_0666	ENOG4105C8Q	Methyl-accepting chemotaxis
B224_0668	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
B224_0669	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
B224_0677	ENOG4109015	Biopolymer transport protein exbD tolR
B224_0688	ENOG410600T	transposase
B224_0691	ENOG4108I5X	binding-protein-dependent transport systems inner membrane Component
B224_0692	ENOG4108IYQ	Binding-protein-dependent transport systems inner membrane component
B224_0693	ENOG4107QRA	Extracellular solute-binding protein, family 5
B224_0696	ENOG4108JQ7	(ABC) transporter
B224_0699	ENOG4105CIN	aminoacyl-histidine dipeptidase
B224_0701	ENOG4105DYA	Acts on guanine, xanthine and to a lesser extent hypoxanthine (By similarity)
B224_0703	ENOG4105V1F	Fermentation respiration switch protein
B224_0704	ENOG4108UVK	Binds to the sigma-S subunit of RNA polymerase, activating expression of sigma-S-regulated genes. Stimulates RNA polymerase holoenzyme formation and may bind to several other sigma factors, such as sigma-70 and sigma-32 (By similarity)
B224_0709	ENOG4105C2S	Catalyzes the NADPH dependent reduction of L-gamma- glutamyl 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate (By similarity)
B224_0723	ENOG4105DG7	nitrate ABC transporter
B224_0724	ENOG4105D7T	ABC transporter
B224_0726	ENOG4107QZF	nitrite reductase NADPH large subunit
B224_0728	ENOG4107QZF	nitrite reductase NADPH large subunit
B224_0730	ENOG4105DD7	kinase (PfkB family
B224_0731	ENOG4105D53	Catalyzes the hydrolysis of pseudouridine 5'-phosphate (PsiMP) to ribose 5-phosphate and uracil (By similarity)
B224_0735	ENOG410600T	transposase
B224_0737	ENOG4105C2D	reductase
B224_0739	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
B224_0742	ENOG4108RIR	Molybdenum cofactor biosynthesis protein
B224_0747	ENOG4105DWK	Membrane
B224_0749	ENOG4107XM3	UPF0442 protein
B224_0752	ENOG4108IJ7	Glycine betaine
B224_0753	ENOG4108HQS	Glycine betaine
B224_0755	ENOG4105GIJ	Glycine betaine
B224_0756	ENOG4105ET3	Reduction of activated sulfate into sulfite (By similarity)
B224_0758	ENOG4105ET1	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate (By similarity)
B224_0760	ENOG4107EER	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity)
B224_0761	ENOG4107TIF	Phenazine biosynthesis protein, PhzF family
B224_0762	ENOG4105CRK	lysyL-tRNA synthetase
B224_0764	ENOG4105CG1	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA (By similarity)
B224_0766	ENOG4105C8Q	Methyl-accepting chemotaxis
B224_0768	ENOG4105BZU	Histidine kinase
B224_0771	ENOG4105D6U	Sodium Glutamate Symporter
B224_0772	ENOG4105HDK	L-asparaginase
B224_0773	ENOG4105VUT	cytoplasmic protein
B224_0778	ENOG4105D07	Signal peptide peptidase, SppA
B224_0781	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
B224_0783	ENOG41069NU	Nitroreductase
B224_0785	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
B224_0787	ENOG4105CIS	alcohol dehydrogenase
B224_0788	ENOG4105HEI	LysR family (Transcriptional regulator
B224_0789	ENOG4105CI1	PTS System
B224_0791	ENOG4108IA2	Sodium pantothenate symporter
B224_0792	ENOG4105RG0	Membrane
B224_0793	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
B224_0795	ENOG4105KM4	Acetyl-CoA carboxylase, biotin carboxyl carrier protein
B224_0796	ENOG4108Z38	Catalyzes a trans-dehydration via an enolate intermediate (By similarity)
B224_0798	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
B224_0801	ENOG4105BZU	Histidine kinase
B224_0804	ENOG4109039	Involved in the biogenesis of TorA. Acts on TorA before the insertion of the molybdenum cofactor and, as a result, probably favors a conformation of the apoenzyme that is competent for acquiring the cofactor (By similarity)
B224_0807	ENOG4108EM1	reductase
B224_0808	ENOG4105CUW	cytochrome C-TYPE protein
B224_0809	ENOG4106WF9	DNA-binding transcriptional regulator TorR
B224_0811	ENOG4108SV3	Tmao reductase system periplasmic protein tort
B224_0812	ENOG4105BZU	Histidine kinase
B224_0815	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
B224_0817	ENOG4108Z11	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes (By similarity)
B224_0818	ENOG4105D1W	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity)
B224_0824	ENOG4108UTT	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity)
B224_0825	ENOG4107YIM	Involved in the transcription termination process (By similarity)
B224_0826	ENOG4105CG2	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity)
B224_0827	ENOG4108ZAI	phosphatidylglycerophosphatase a
B224_0829	ENOG4108JQ6	ABC transporter
B224_0833	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
B224_0836	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
B224_0838	ENOG4105CTB	Polyprenyl synthetase
B224_0840	ENOG41067QG	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
B224_0842	ENOG4105E14	MotA TolQ exbB proton channel
B224_0843	ENOG4107XSU	flagellar motor protein motb
B224_0844	ENOG4108UKH	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
B224_0846	ENOG4105HBR	Rna-binding protein
B224_0847	ENOG4105F7M	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit (By similarity)
B224_0848	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
B224_0850	ENOG4105EEI	dihydropteroate synthase
B224_0852	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
B224_0854	ENOG4105CP7	Triose-phosphate isomerase
B224_0856	ENOG4105K7D	Required for maturation of 30S ribosomal subunits (By similarity)
B224_0857	ENOG4105CHV	Transcription elongation factor NusA
B224_0860	ENOG4107QHU	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
B224_0861	ENOG4105KG7	Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity)
B224_0862	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
B224_0864	ENOG4105K77	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity)
B224_0865	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
B224_0869	ENOG41090EX	DsrE family
B224_0871	ENOG4105K5D	4fe-4S ferredoxin iroN-sulfur binding
B224_0873	ENOG4105CFP	Peptidase U32
B224_0874	ENOG4107N1Q	ErfK YbiS YcfS YnhG family protein
B224_0879	ENOG4105D1U	peptidase U62 modulator of DNA gyrase
B224_0880	ENOG41071R3	Low-potential electron donor to a number of redox enzymes (By similarity)
B224_0881	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
B224_0888	ENOG4105C31	Tryptophanyl-tRNA synthetase
B224_0890	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
B224_0891	ENOG4105DJV	ribulose-phosphate 3-epimerase
B224_0892	ENOG4105DFE	Dna adenine methylase
B224_0895	ENOG4105D49	3-dehydroquinate synthase
B224_0897	ENOG4105KHV	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
B224_0905	ENOG4108JQC	penicillin-binding protein 1A
B224_0907	ENOG4105C5Q	Transcriptional regulator
B224_0910	ENOG4105EJC	lysr family transcriptional regulator
B224_0914	ENOG4108VEV	chaperone
B224_0917	ENOG4105CW0	outer membrane usher protein
B224_0918	ENOG4108VEV	chaperone
B224_0921	ENOG4105DR5	peptidase
B224_0925	ENOG4105EGS	Mechanosensitive ion channel
B224_0927	ENOG4108QXE	glycerophosphoryl diester phosphodiesterase
B224_0929	ENOG4105C8Q	Methyl-accepting chemotaxis
B224_0932	ENOG4105E33	succinate dehydrogenase
B224_0933	ENOG4108WJH	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane (By similarity)
B224_0934	ENOG4108VP9	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane (By similarity)
B224_0936	ENOG4105T0Z	Conserved Protein
B224_0937	ENOG4105DA6	Catalyzes the conversion of 5-methoxyuridine (mo5U) to uridine-5-oxyacetic acid (cmo5U) at position 34 in tRNA. May also participate in the methylation of uridine-5-oxyacetic acid (cmo5U) to uridine-5-oxyacetic acid methyl ester (mcmo5U) (By similarity)
B224_0941	ENOG4108IXY	short-chain dehydrogenase reductase
B224_0943	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
B224_0944	ENOG4105DHQ	Histidine kinase
B224_0947	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
B224_0951	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
B224_0952	ENOG4108R5S	membrane
B224_0955	ENOG4105C5I	Dehydrogenase
B224_0958	ENOG4105BZU	Histidine kinase
B224_0963	ENOG4105EVE	HAD-superfamily hydrolase subfamily IA variant 3
B224_0965	ENOG4105F04	LysR family Transcriptional regulator
B224_0966	ENOG4105VEQ	Cold shock protein
B224_0968	ENOG4105EAK	ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family
B224_0969	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
B224_0970	ENOG4105C9A	Phoh family
B224_0972	ENOG4105KGE	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA (By similarity)
B224_0973	ENOG4108JU5	Magnesium and cobalt efflux protein
B224_0975	ENOG4105CE8	Transfers the fatty acyl group on membrane lipoproteins (By similarity)
B224_0977	ENOG4107PAI	alpha helical protein
B224_0979	ENOG4105C8T	Leucyl-tRNA synthetase
B224_0985	ENOG4108Z1W	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity)
B224_0986	ENOG4105KEM	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation (By similarity)
B224_0988	ENOG4108UXA	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA (By similarity)
B224_0989	ENOG4105CJN	penicillin-binding protein
B224_0991	ENOG4105CNI	cell division protein FtsW
B224_0992	ENOG4105CVE	Lytic murein transglycosylase
B224_0993	ENOG4105K6T	rare lipoprotein A
B224_0994	ENOG4105DZ1	carboxypeptidase
B224_0996	ENOG4108Z43	UPF0250 protein
B224_0997	ENOG4108BDP	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity)
B224_0998	ENOG4105C0G	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity)
B224_1001	ENOG4108IUB	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
B224_1005	ENOG4105C2R	Single-stranded-DNA-specific exonuclease (RecJ)
B224_1010	ENOG4105M2E	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell (By similarity)
B224_1017	ENOG4105C8Y	Acetylornithine aminotransferase
B224_1019	ENOG4105F4X	arginine
B224_1021	ENOG4105C26	Dehydrogenase
B224_1024	ENOG4107VXZ	Hydrolase
B224_1029	ENOG4105N5Z	UPF0267 protein
B224_1032	ENOG4107QWE	)-transporter
B224_1033	ENOG4105C3G	gtp-binding protein
B224_1035	ENOG4108ZPD	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity)
B224_1036	ENOG4105CGH	5'-nucleotidase
B224_1038	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
B224_1040	ENOG4105C1U	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein (By similarity)
B224_1042	ENOG4105C7E	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) (By similarity)
B224_1043	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
B224_1044	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
B224_1047	ENOG41063JG	Transcriptional regulator
B224_1048	ENOG4105CXR	Phospho-2-dehydro-3-deoxyoctonate aldolase
B224_1049	ENOG4105CK2	sodium dicarboxylate symporter
B224_1050	ENOG4108VKA	Acts as a radical domain for damaged PFL and possibly other radical proteins (By similarity)
B224_1051	ENOG4105D5S	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine (By similarity)
B224_1057	ENOG410600T	transposase
B224_1058	ENOG4105CW3	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
B224_1060	ENOG4105BZG	amino acid carrier protein
B224_1061	ENOG41066YJ	Beta-lactamase
B224_1066	ENOG4107Y66	Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity)
B224_1067	ENOG4108UJU	UPF0301 protein
B224_1068	ENOG4105D7Z	glutathione synthase
B224_1070	ENOG4105QF0	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity)
B224_1072	ENOG4105GPY	SprT protein
B224_1073	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
B224_1074	ENOG4105CV1	Transketolase (EC 2.2.1.1)
B224_1077	ENOG4105CMM	transposase
B224_1083	ENOG4105ED7	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling (By similarity)
B224_1085	ENOG4105DR5	peptidase
B224_1087	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
B224_1090	ENOG4107WCA	isomerase
B224_1093	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
B224_1096	ENOG4105C87	Aminotransferase class I and II
B224_1101	ENOG4105C5Q	Transcriptional regulator
B224_1102	ENOG4105UBK	short-chain dehydrogenase reductase
B224_1103	ENOG4105ERU	peptidase
B224_1104	ENOG4105EY2	Catalyzes the hydrolysis of N(2)-succinylarginine into N(2)-succinylornithine, ammonia and CO(2) (By similarity)
B224_1107	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
B224_1111	ENOG4107RHT	methyl-accepting chemotaxis sensory transducer with Pas Pac sensor
B224_1113	ENOG4105E2D	ec 3.2.1.52
B224_1114	ENOG4105RD7	BadF BadG BcrA BcrD
B224_1117	ENOG4108JQ7	(ABC) transporter
B224_1120	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
B224_1125	ENOG4105CBM	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 (By similarity)
B224_1126	ENOG4105EUK	rtx toxin RtxA
B224_1129	ENOG4105CBM	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 (By similarity)
B224_1136	ENOG4105DIJ	Phosphoethanolamine transferase
B224_1140	ENOG4105F2I	Transposase
B224_1142	ENOG4105F2I	Transposase
B224_1148	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
B224_1157	ENOG4105F2I	Transposase
B224_1164	ENOG4105CBS	Chea signal transduction histidine kinase
B224_1166	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
B224_1168	ENOG4105E14	MotA TolQ exbB proton channel
B224_1169	ENOG4108SEK	ompa motb domain protein
B224_1170	ENOG4107QJE	Chromosome Partitioning Protein
B224_1173	ENOG4108V3W	Chemotaxis protein, CheW
B224_1176	ENOG4105CA5	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes (By similarity)
B224_1178	ENOG41060IM	Heme exporter protein
B224_1180	ENOG4105X3C	heme exporter protein
B224_1181	ENOG4108ZKK	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH (By similarity)
B224_1182	ENOG4105DA4	cytochrome c-type biogenesis protein
B224_1184	ENOG4107QX9	Thiol disulfide interChange protein
B224_1185	ENOG4105KWW	Biogenesis protein
B224_1188	ENOG410903C	(LipO)protein
B224_1190	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
B224_1191	ENOG4105M2J	Glutaredoxin
B224_1198	ENOG4108S7T	Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) (By similarity)
B224_1199	ENOG4107R11	Transcriptional regulator
B224_1204	ENOG4105E18	UPF0276 protein
B224_1211	ENOG4107SDU	Methyl-accepting chemotaxis
B224_1214	ENOG4108ESY	Metal dependent phosphohydrolase
B224_1216	ENOG4105FNP	Molybdopterin-guanine dinucleotide biosynthesis protein b
B224_1217	ENOG4105C6R	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor (By similarity)
B224_1218	ENOG4107R1I	NAD-dependent malic enzyme
B224_1220	ENOG4105C2W	permease
B224_1230	ENOG410600T	transposase
B224_1231	ENOG410600T	transposase
B224_1233	ENOG4105C2J	ABC transporter
B224_1236	ENOG4105CNN	ABC, transporter
B224_1238	ENOG4105D17	glycoside hydrolase, family 3 domain protein
B224_1244	ENOG4105EGS	Mechanosensitive ion channel
B224_1246	ENOG4105CA9	Pyruvate kinase
B224_1247	ENOG4105EZE	Cupin 4 family protein
B224_1248	ENOG4107QTF	adenylosuccinate lyase
B224_1249	ENOG41075W9	High frequency lysogenization protein HflD homolog
B224_1251	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
B224_1253	ENOG4108R99	pseudouridine synthase
B224_1255	ENOG4108YRF	PTS System
B224_1258	ENOG4105CXY	transporter
B224_1261	ENOG4105DM4	PTS System
B224_1266	ENOG4107VGF	ig domain protein group 2 domain protein
B224_1269	ENOG4105DM4	PTS System
B224_1271	ENOG4105P66	Membrane
B224_1274	ENOG4105EIP	mannose-6-phosphate isomerase
B224_1275	ENOG4106R3P	AraC family transcriptional regulator
B224_1276	ENOG4108HMX	isocitrate dehydrogenase (NADP)
B224_1280	ENOG4105VNT	transposase (IS4 family) protein
B224_1283	ENOG4105BZC	d-serine deaminase
B224_1285	ENOG4105W8I	Transcriptional regulator
B224_1288	ENOG4105Q26	Siderophore-interacting protein
B224_1290	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
B224_1291	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
B224_1294	ENOG4105DJY	efflux transporter, rnd family, mfp subunit
B224_1296	ENOG4105E2M	Manganese-dependent inorganic pyrophosphatase
B224_1297	ENOG4105C4F	May be involved in recombinational repair of damaged DNA (By similarity)
B224_1300	ENOG4105BZU	Histidine kinase
B224_1302	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
B224_1303	ENOG4105K90	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
B224_1305	ENOG4105CFG	Acts as a chaperone (By similarity)
B224_1307	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
B224_1310	ENOG4105D7K	pfkb domain protein
B224_1315	ENOG4105WBN	Transcriptional regulator (LacI family
B224_1321	ENOG41080HT	Transcriptional regulator, arsr family
B224_1323	ENOG4105KFG	YeeE YedE family protein
B224_1331	ENOG4105BZU	Histidine kinase
B224_1332	ENOG4107RMF	Catalyzes both the ATP-dependent activation of exogenously supplied lipoate to lipoyl-AMP and the transfer of the activated lipoyl onto the lipoyl domains of lipoate-dependent enzymes (By similarity)
B224_1336	ENOG4105D7V	transposase
B224_1339	ENOG4108IJF	Heavy metal efflux pump, CzcA
B224_1343	ENOG4105EP1	Efflux transporter rnd family, mfp subunit
B224_1346	ENOG4105CGK	Exodeoxyribonuclease III
B224_1352	ENOG4105VN1	Heat shock protein
B224_1361	ENOG4105CC0	LysR family Transcriptional regulator
B224_1362	ENOG4105MDH	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity (By similarity)
B224_1364	ENOG410600T	transposase
B224_1365	ENOG4105E2S	oxidase) subunit II
B224_1368	ENOG4105BZ9	Cytochrome C oxidase, subunit I
B224_1370	ENOG4105CCU	oxidase (Subunit III)
B224_1371	ENOG41090KH	cytochrome o ubiquinol oxidase (subunit iv)
B224_1372	ENOG4105F1R	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group (By similarity)
B224_1375	ENOG4107RDB	Major Facilitator
B224_1377	ENOG4105KCV	RNA signal recognition particle 4.5S RNA
B224_1381	ENOG4105JQN	Transcriptional regulator
B224_1387	ENOG4105CAF	HipA N-terminal domain protein
B224_1389	ENOG410600T	transposase
B224_1399	ENOG41090SZ	ABC-2 type transporter
B224_1400	ENOG4107V1M	polysaccharide export protein
B224_1405	ENOG4105F1A	Pyruvate formate-lyase
B224_1407	ENOG4105BZU	Histidine kinase
B224_1409	ENOG4107QMW	pyridine nucleotide-disulfide oxidoreductase
B224_1410	ENOG4105F2I	Transposase
B224_1411	ENOG4105R9B	Major Facilitator
B224_1415	ENOG4105J12	Multidrug resistance protein mdtN
B224_1421	ENOG4105DN3	alpha-2-macroglobulin domain protein
B224_1422	ENOG4108JQB	penicillin-binding protein 1C
B224_1425	ENOG4105D8I	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS (By similarity)
B224_1429	ENOG4105EN6	Membrane
B224_1430	ENOG4105I03	Flagellin
B224_1434	ENOG410600T	transposase
B224_1436	ENOG4105F2I	Transposase
B224_1440	ENOG4105JKQ	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Binds vitamin B12 and delivers it to the periplasmic surface of BtuC (By similarity)
B224_1443	ENOG4105DUF	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively (By similarity)
B224_1447	ENOG4108UYE	Lactoylglutathione lyase
B224_1448	ENOG4105CSM	endonuclease III
B224_1449	ENOG4105DZB	Electron transport complex
B224_1451	ENOG4108UQQ	Electron transport complex
B224_1454	ENOG4105D6A	Electron transport complex
B224_1458	ENOG4108R3D	Electron transport complex
B224_1459	ENOG4105DGN	Electron transport complex
B224_1460	ENOG4108PCN	EamA-like transporter family
B224_1464	ENOG4107SDU	Methyl-accepting chemotaxis
B224_1466	ENOG4105RKW	reductase (By
B224_1467	ENOG4105CSX	c4-dicarboxylate anaerobic carrier
B224_1468	ENOG4105CHM	Aminotransferase
B224_1471	ENOG41090BQ	Glutaredoxin
B224_1473	ENOG4106HRJ	d-alanyl-d-alanine carboxypeptidase
B224_1474	ENOG4105CFI	type iii restriction protein res subunit
B224_1476	ENOG4105EFX	secretion protein, HlyD family
B224_1477	ENOG4105KK7	inner membrane protein YiaW
B224_1478	ENOG4105EGS	Mechanosensitive ion channel
B224_1481	ENOG4108NEV	two component transcriptional regulator, LytTR family
B224_1482	ENOG4108HRK	Histidine kinase
B224_1483	ENOG4105CPI	Metal Dependent Phosphohydrolase
B224_1485	ENOG4108EKI	Dehydrogenase
B224_1488	ENOG4105EZI	multiple antibiotic resistance (MarC)-related protein
B224_1489	ENOG4107QSI	ABC, transporter
B224_1491	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
B224_1492	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
B224_1493	ENOG4105C3U	ABC transporter
B224_1494	ENOG4108JQ7	(ABC) transporter
B224_1495	ENOG4105DU1	integral membrane protein, terc
B224_1498	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
B224_1501	ENOG4107QJT	sodium dicarboxylate symporter
B224_1505	ENOG4105CD3	dihydroorotase
B224_1510	ENOG4105K59	histidine triad (HIT) protein
B224_1519	ENOG4105D7V	transposase
B224_1521	ENOG4107QN8	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
B224_1524	ENOG4107RAB	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
B224_1527	ENOG4105CKW	Inner membrane protein yedI
B224_1533	ENOG4105DPN	Oligoendopeptidase f
B224_1535	ENOG4105CEP	NADH dehydrogenase
B224_1538	ENOG4105K8R	UPF0145 protein
B224_1540	ENOG4105EBE	Peptidase U61, LD-carboxypeptidase A
B224_1542	ENOG4105EBE	Peptidase U61, LD-carboxypeptidase A
B224_1544	ENOG4107T7U	Sulfatase
B224_1547	ENOG4105CFH	Aspartokinase
B224_1549	ENOG4107QZM	n-acetylglutamate synthase
B224_1551	ENOG4107QXP	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
B224_1554	ENOG4105MSB	protein, conserved in bacteria
B224_1556	ENOG4105CR8	Transcriptional regulator
B224_1557	ENOG4105DAA	L-lactate
B224_1559	ENOG4105CHG	glycolate oxidase (iron-sulfur subunit)
B224_1560	ENOG4107QR9	Iron-sulfur cluster binding protein
B224_1561	ENOG4108ZZK	Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source (By similarity)
B224_1564	ENOG4105F2I	Transposase
B224_1569	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
B224_1575	ENOG4105C2C	drug resistance transporter, Bcr CflA
B224_1601	ENOG4105DFP	Integrase
B224_1609	ENOG4105CHH	sulfate transporter
B224_1611	ENOG4105F2I	Transposase
B224_1612	ENOG4105F3K	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity)
B224_1614	ENOG4105CJX	Molecular chaperone. Has ATPase activity (By similarity)
B224_1617	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
B224_1619	ENOG4105CFX	Catalyzes the ferrous insertion into protoporphyrin IX (By similarity)
B224_1621	ENOG4107RE1	Inosine-guanosine kinase
B224_1623	ENOG4105CFX	Catalyzes the ferrous insertion into protoporphyrin IX (By similarity)
B224_1625	ENOG4107RE1	Inosine-guanosine kinase
B224_1628	ENOG4105C8Q	Methyl-accepting chemotaxis
B224_1633	ENOG4105BZU	Histidine kinase
B224_1635	ENOG4107QQ4	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans (By similarity)
B224_1639	ENOG4105F3T	(LipO)protein
B224_1642	ENOG4108IQC	2,3-dihydroxybenzoate-AMP ligase
B224_1644	ENOG4105WQI	isochorismatase
B224_1648	ENOG4105WQI	isochorismatase
B224_1649	ENOG4105CEY	Amp-dependent synthetase and ligase
B224_1651	ENOG4105X17	23-dihydro-2,3-dihydroxybenzoate dehydrogenase
B224_1657	ENOG4105CEY	Amp-dependent synthetase and ligase
B224_1661	ENOG4108TSE	Transferase
B224_1662	ENOG4105E0A	ABC, transporter
B224_1664	ENOG4105TVJ	transport system, permease
B224_1665	ENOG4105DQ5	transport system permease protein
B224_1666	ENOG4105D05	Receptor
B224_1671	ENOG4105QZU	Inner membrane protein YfeZ
B224_1673	ENOG4107QUT	magnesium and cobalt transport protein CorA
B224_1674	ENOG4105DWH	electron transfer flavoprotein-ubiquinone oxidoreductase
B224_1675	ENOG4105BZJ	Electron transfer flavoprotein
B224_1676	ENOG4105C10	Electron transfer flavoprotein
B224_1678	ENOG4107QM1	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine (By similarity)
B224_1679	ENOG4105CMY	5-enolpyruvylshikimate-3-phosphate synthase
B224_1681	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
B224_1682	ENOG4105EE5	Membrane protein terC
B224_1685	ENOG4105MH2	YfcL protein
B224_1686	ENOG4108IQE	Amp-dependent synthetase and ligase
B224_1688	ENOG4107T42	This enzyme scavenge exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis (By similarity)
B224_1689	ENOG41067MG	lrgb family
B224_1690	ENOG4105VAW	lrga family
B224_1691	ENOG4107R49	K07407 alpha-galactosidase EC 3.2.1.22
B224_1695	ENOG4105CJB	Exodeoxyribonuclease I
B224_1696	ENOG4105DFP	Integrase
B224_1697	ENOG4108UUM	single-stranded DNA-binding protein
B224_1709	ENOG4105DS7	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity)
B224_1716	ENOG4106050	phage regulatory protein, rha family
B224_1724	ENOG4105FKG	DNA packaging protein
B224_1725	ENOG4105UZW	Tail fiber assembly protein
B224_1728	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
B224_1754	ENOG4105FF5	Membrane
B224_1757	ENOG4105E89	ABC transporter
B224_1764	ENOG4105CHM	Aminotransferase
B224_1765	ENOG4105ETT	transcriptional Regulator, LysR family
B224_1767	ENOG4105CAC	Catalyzes the conversion of L-arabinose to L-ribulose (By similarity)
B224_1770	ENOG4105EF1	ribulokinase
B224_1771	ENOG4105DMK	Periplasmic binding protein LacI transcriptional regulator
B224_1772	ENOG4105C2J	ABC transporter
B224_1774	ENOG4105CNN	ABC, transporter
B224_1777	ENOG41074DU	domain protein
B224_1778	ENOG4108P2H	Inner membrane protein YjiG
B224_1779	ENOG4105DYB	Isoaspartyl dipeptidase
B224_1784	ENOG4105CNN	ABC, transporter
B224_1787	ENOG4105NRA	50s ribosomal protein l31 type b
B224_1790	ENOG4108VKG	metal-dependent hydrolase
B224_1795	ENOG4105CEE	C4-dicarboxylate transporter
B224_1798	ENOG4105D70	Integrase catalytic subunit
B224_1799	ENOG4105F5W	AtP-binding protein
B224_1810	ENOG410600T	transposase
B224_1811	ENOG4105F2I	Transposase
B224_1813	ENOG4105F2I	Transposase
B224_1814	ENOG410600T	transposase
B224_1818	ENOG410600T	transposase
B224_1825	ENOG4105HA9	of methanol dehydrogenase type
B224_1827	ENOG4105HPZ	Involved in the removal of murein from the sacculus. May also facilitate integration of nascent murein strands into the sacculus by cleaving the peptide bonds between neighboring strands in mature murein (By similarity)
B224_1829	ENOG4105VFU	Rna-binding protein
B224_1830	ENOG4107RGM	aldo keto reductase
B224_1836	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
B224_1838	ENOG4105CBN	LysR family transcriptional regulator
B224_1840	ENOG4105BZU	Histidine kinase
B224_1844	ENOG4105CFC	Transporter
B224_1846	ENOG4108DBC	nitroreductase
B224_1851	ENOG4105D2S	major facilitator superfamily
B224_1852	ENOG4105DUM	transcriptional regulator, lysR family
B224_1853	ENOG4108JEN	Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate (By similarity)
B224_1854	ENOG4105CAT	Cytidine monophosphate kinase
B224_1855	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
B224_1857	ENOG41080YA	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
B224_1859	ENOG4105CFV	Tetratricopeptide repeat protein
B224_1860	ENOG4106EG9	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) (By similarity)
B224_1863	ENOG4105FD2	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) (By similarity)
B224_1865	ENOG4105EIZ	Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity)
B224_1866	ENOG4105VRT	cytoplasmic protein
B224_1867	ENOG4108WBT	adenosyltransferase
B224_1869	ENOG410600T	transposase
B224_1873	ENOG4107S6Z	Na H antiporter
B224_1875	ENOG4107104	thymidine kinase
B224_1877	ENOG4108RMJ	sensory transduction regulator
B224_1888	ENOG4105CGY	Dna recombination protein
B224_1890	ENOG410626R	Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity)
B224_1893	ENOG4105CAF	HipA N-terminal domain protein
B224_1900	ENOG410600T	transposase
B224_1918	ENOG410600T	transposase
B224_1919	ENOG4105F2I	Transposase
B224_1921	ENOG410600T	transposase
B224_1925	ENOG4108UUM	single-stranded DNA-binding protein
B224_1926	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
B224_1927	ENOG4105KT5	UmuD protein
B224_1930	ENOG4105F5W	AtP-binding protein
B224_1947	ENOG4105C3J	Cysteine desulfurase
B224_1955	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
B224_1958	ENOG4105C28	cystathionine
B224_1961	ENOG4108RYK	Nad-dependent epimerase dehydratase
B224_1962	ENOG4105CR8	Transcriptional regulator
B224_1966	ENOG4105UEI	Transcriptional Regulator AraC Family
B224_1968	ENOG4105E0K	tonB-dependent siderophore receptor
B224_1971	ENOG4105DZ2	Transcriptional regulator
B224_1972	ENOG4105DSS	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation (By similarity)
B224_1981	ENOG4105MWK	D-amino acid dehydrogenase, small subunit
B224_1984	ENOG4105EXX	Deoxyribodipyrimidine photolyase-related protein
B224_1985	ENOG41061WM	D-Alanyl-D-Alanine
B224_1986	ENOG4108DMF	Cytochrome C biogenesis protein
B224_1987	ENOG4107QX9	Thiol disulfide interChange protein
B224_1989	ENOG4105DA4	cytochrome c-type biogenesis protein
B224_1991	ENOG4105DVI	reductase, NrfD
B224_1992	ENOG4105D3S	4Fe-4S Ferredoxin, iron-sulfur binding domain protein
B224_1993	ENOG4105JJ8	Cytochrome c nitrite reductase, pentaheme subunit
B224_2003	ENOG4105CHG	glycolate oxidase (iron-sulfur subunit)
B224_2005	ENOG4108KJ0	anaerobic glycerol-3-phosphate dehydrogenase, subunit B
B224_2007	ENOG4107R5Y	anaerobic glycerol-3-phosphate dehydrogenase, subunit A
B224_2008	ENOG4105K5B	UPF0225 protein
B224_2009	ENOG4105C8Q	Methyl-accepting chemotaxis
B224_2011	ENOG4105E2R	ROK family
B224_2013	ENOG4105CEQ	signal transduction histidine kinase regulating citrate malate metabolism
B224_2014	ENOG4108MRH	transcriptional regulatory protein
B224_2022	ENOG4105CHQ	Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella (By similarity)
B224_2024	ENOG4105D0C	transport protein
B224_2027	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
B224_2029	ENOG4105DQR	SNARE associated Golgi
B224_2030	ENOG410635M	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein (By similarity)
B224_2031	ENOG4105DKR	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity)
B224_2032	ENOG4105C05	Multifunctional regulator of fatty acid metabolism (By similarity)
B224_2033	ENOG4105ED1	spovr family
B224_2034	ENOG4106AKX	UPF0229 protein
B224_2036	ENOG4105CYN	Serine protein kinase
B224_2039	ENOG4105C9U	ATP-dependent DNA helicase RecQ
B224_2040	ENOG4107QV7	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system) (By similarity)
B224_2042	ENOG4105C44	Serine transporter
B224_2043	ENOG410600T	transposase
B224_2054	ENOG4107QQN	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties (By similarity)
B224_2057	ENOG4105C8P	)-transporter
B224_2060	ENOG4105K63	Thioredoxin
B224_2061	ENOG4105BZU	Histidine kinase
B224_2064	ENOG4105BZ1	(ABC) transporter
B224_2066	ENOG4105BZ1	(ABC) transporter
B224_2071	ENOG410600T	transposase
B224_2075	ENOG4105WQ3	Rna-binding protein
B224_2078	ENOG4105D1N	poly(r)-hydroxyalkanoic acid synthase, class
B224_2083	ENOG4107XGF	functions in a salvage pathway. Uses pyridoxamine (By similarity)
B224_2084	ENOG41061CK	Antibiotic biosynthesis monooxygenase
B224_2087	ENOG4105EFU	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin (By similarity)
B224_2089	ENOG4105DUM	transcriptional regulator, lysR family
B224_2092	ENOG4105D1S	lipid A biosynthesis
B224_2094	ENOG4105D1S	lipid A biosynthesis
B224_2098	ENOG4105EUB	pirin domain protein
B224_2101	ENOG4105CQ2	DNA polymerase
B224_2102	ENOG4107QI1	Mate efflux family protein
B224_2104	ENOG4105W1I	UPF0253 protein
B224_2105	ENOG4108R6K	riboflavin synthase, subunit alpha
B224_2106	ENOG4105D7V	transposase
B224_2109	ENOG4107UW8	HAD-superfamily hydrolase subfamily IA variant 3
B224_2110	ENOG4108HH9	Catalyzes two reactions the first one is the production of beta-formyl glycinamide ribonucleotide (GAR) from formate, ATP and beta GAR
B224_2111	ENOG4108SXK	Transporter Drug Metabolite Exporter family
B224_2112	ENOG4108V3G	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity)
B224_2124	ENOG4105XW2	UPF0263 protein
B224_2125	ENOG4108VKV	Monofunctional biosynthetic peptidoglycan transglycosylase
B224_2127	ENOG4105VJP	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell (By similarity)
B224_2128	ENOG4107QMS	site-determining protein
B224_2129	ENOG4105K7U	Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization (By similarity)
B224_2130	ENOG4105VNG	YcgL domain-containing protein
B224_2131	ENOG4105CVE	Lytic murein transglycosylase
B224_2133	ENOG4105EJQ	L-serine dehydratase
B224_2135	ENOG4105EJQ	L-serine dehydratase
B224_2137	ENOG4105NBK	UPF0345 protein
B224_2138	ENOG4105CK2	sodium dicarboxylate symporter
B224_2141	ENOG4105CHU	acetyl-coa acetyltransferase
B224_2143	ENOG4105CKF	membrane protein involved in aromatic hydrocarbon degradation
B224_2146	ENOG4105D58	Diguanylate phosphodiesterase
B224_2147	ENOG4105CKF	membrane protein involved in aromatic hydrocarbon degradation
B224_2148	ENOG4105CKF	membrane protein involved in aromatic hydrocarbon degradation
B224_2159	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
B224_2160	ENOG4105CHU	acetyl-coa acetyltransferase
B224_2161	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
B224_2165	ENOG4108VWS	Yaeq family
B224_2175	ENOG4105D5G	Transposase
B224_2182	ENOG4105EHG	Permease protein
B224_2188	ENOG4107MBR	17 kDa surface antigen
B224_2189	ENOG4105CEY	Amp-dependent synthetase and ligase
B224_2190	ENOG4105D29	Helix-turn-helix type 11 domain protein
B224_2193	ENOG4105K8F	Phosphoribosyl-amp cyclohydrolase
B224_2194	ENOG4105C0S	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity)
B224_2196	ENOG4105BZU	Histidine kinase
B224_2199	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
B224_2201	ENOG410600T	transposase
B224_2204	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
B224_2205	ENOG4105CJV	Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase
B224_2206	ENOG4108UJE	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity)
B224_2209	ENOG4105CIH	Imidazole acetol-phosphate transaminase
B224_2210	ENOG4105CEK	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity)
B224_2211	ENOG4105E21	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity)
B224_2214	ENOG4105DVT	helicase
B224_2215	ENOG41072GX	Peptidase M22 Glycoprotease
B224_2218	ENOG4107J5P	Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC). Is also able to catalyze the hydrolysis of the thioester bond in palmitoyl-CoA in vitro (By similarity)
B224_2220	ENOG4105CEY	Amp-dependent synthetase and ligase
B224_2221	ENOG4105ZIE	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides (By similarity)
B224_2223	ENOG4105DXC	membrane
B224_2228	ENOG4105FBT	Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs (By similarity)
B224_2229	ENOG4105WD1	Membrane
B224_2230	ENOG4109003	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity)
B224_2233	ENOG4107QMP	dna polymerase iii subunits gamma and tau
B224_2234	ENOG4105KDX	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection (By similarity)
B224_2235	ENOG4105CHJ	isochorismatase hydrolase
B224_2236	ENOG4105EUB	pirin domain protein
B224_2237	ENOG4105JQN	Transcriptional regulator
B224_2239	ENOG4105DWD	nucleoside recognition domain protein
B224_2245	ENOG4105CQ7	ATP-dependent helicase
B224_2247	ENOG4105KW6	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance (By similarity)
B224_2248	ENOG4105BZU	Histidine kinase
B224_2249	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
B224_2251	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
B224_2252	ENOG4105C5X	domain protein
B224_2253	ENOG4105CR7	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA (By similarity)
B224_2254	ENOG4105D4F	Synthesizes selenophosphate from selenide and ATP (By similarity)
B224_2256	ENOG4105DR4	Methyltransferase
B224_2258	ENOG4108N3W	hemolysin secretion protein
B224_2260	ENOG4105VSY	K01512 acylphosphatase EC 3.6.1.7
B224_2263	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
B224_2264	ENOG4105D1F	ATP-binding protein
B224_2265	ENOG4105DBI	uridine monophosphokinase
B224_2266	ENOG4105DHP	deoxycytidine triphosphate deaminase
B224_2268	ENOG4105CJ3	phosphate transporter
B224_2270	ENOG4105D70	Integrase catalytic subunit
B224_2274	ENOG4105F5W	AtP-binding protein
B224_2278	ENOG4105C03	ribonuclease
B224_2279	ENOG4105EI2	Pseudouridine synthase
B224_2280	ENOG4108YZS	Had-superfamily hydrolase, subfamily ia, variant 1
B224_2281	ENOG4108UHJ	MAF-like protein
B224_2283	ENOG4105FCQ	metal-binding, possibly nucleic acid-binding protein
B224_2285	ENOG4105VGS	50s ribosomal protein l32
B224_2286	ENOG4105C6B	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA (By similarity)
B224_2287	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
B224_2288	ENOG4105CJF	Malonyl coA-acyl carrier protein transacylase
B224_2290	ENOG4105CHR	reductase
B224_2291	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
B224_2293	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
B224_2295	ENOG4105YAZ	4-amino-4-deoxychorismate lyase
B224_2296	ENOG4105HHA	aminodeoxychorismate lyase
B224_2297	ENOG4108ZMD	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity)
B224_2299	ENOG4107QRG	dna polymerase iii
B224_2300	ENOG4105F8V	Hydrolase, tatD family
B224_2304	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
B224_2306	ENOG4105DY2	Paraquat-inducible protein b
B224_2308	ENOG4105H2K	paraquat-inducible protein a
B224_2311	ENOG4105X2V	dna damage-inducible protein
B224_2314	ENOG4105DAN	ATP-dependent protease
B224_2315	ENOG4108RKI	Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl- ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)- decenoyl-ACP. Can catalyze the dehydratase reaction for beta- hydroxyacyl-ACPs with saturated chain lengths up to 16 0, being most active on intermediate chain length (By similarity)
B224_2316	ENOG4105WFT	During stationary phase, converts 70S ribosomes to an inactive dimeric form (100S ribosomes) (By similarity)
B224_2318	ENOG4105C5H	ABC transporter
B224_2320	ENOG4105C4H	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA (By similarity)
B224_2321	ENOG4108T7E	Contributes to the efficiency of the cell division process by stabilizing the polymeric form of the cell division protein FtsZ. Acts by promoting interactions between FtsZ protofilaments and suppressing the GTPase activity of FtsZ (By similarity)
B224_2322	ENOG4107QYT	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor (By similarity)
B224_2325	ENOG4105C7I	Dehydrogenase
B224_2327	ENOG4105CD8	aminopeptidase N
B224_2329	ENOG4105CN1	protease
B224_2330	ENOG41073DY	may be a structural element that influences the osmotic activation of ProP at a post-translational level (By similarity)
B224_2331	ENOG4108ZGC	gaf domain protein
B224_2333	ENOG4105EUH	cytochrome C oxidase, cbb3-type, subunit i
B224_2337	ENOG4105D6P	C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex (By similarity)
B224_2343	ENOG4105DS0	Transcriptional regulator, Crp Fnr family
B224_2344	ENOG4105Q9Y	Universal stress protein
B224_2345	ENOG4105CB3	Required for the thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32) (By similarity)
B224_2348	ENOG4108K3A	Glutathione S-transferase
B224_2349	ENOG4105MRB	Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose (By similarity)
B224_2351	ENOG4105C2J	ABC transporter
B224_2352	ENOG4105CNN	ABC, transporter
B224_2353	ENOG4105E9V	Periplasmic binding protein LacI transcriptional regulator
B224_2354	ENOG4108RVA	ribokinase
B224_2355	ENOG4105ETE	Transcriptional regulator (LacI family
B224_2357	ENOG4105BZU	Histidine kinase
B224_2359	ENOG4105NDF	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity)
B224_2365	ENOG4105BZU	Histidine kinase
B224_2366	ENOG4108ZUF	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
B224_2368	ENOG4105C6A	phenylalanyl-tRNA synthetase (beta subunit)
B224_2369	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
B224_2371	ENOG4108YZX	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity)
B224_2373	ENOG4108UUX	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity)
B224_2374	ENOG4105C22	threonyL-tRNA synthetase
B224_2381	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
B224_2382	ENOG4108HWB	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
B224_2383	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
B224_2385	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
B224_2387	ENOG4105E05	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
B224_2388	ENOG4105XPH	Ferredoxin
B224_2390	ENOG4105CA3	membrane-bound lytic murein transglycosylase
B224_2391	ENOG4105XZD	Fe-S protein
B224_2394	ENOG4105DM4	PTS System
B224_2395	ENOG4105DE4	1-phosphofructokinase
B224_2397	ENOG4105DTZ	bifunctional PTS system fructose-specific transporter subunit IIA HPr protein
B224_2399	ENOG4107B7Y	DNA-binding transcriptional regulator FruR
B224_2400	ENOG4105E0U	tyrosine-specific transport protein
B224_2401	ENOG4105WJG	Glutathione
B224_2403	ENOG4105C1J	atp-dependent rna helicase
B224_2405	ENOG4105D10	5-enolpyruvylshikimate-3-phosphate phospholyase
B224_2406	ENOG4105C76	Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue (By similarity)
B224_2407	ENOG4108DG9	Smr protein MutS2
B224_2409	ENOG4107TB6	phosphoglycerate mutase
B224_2418	ENOG4108Z8G	Alkylphosphonate utilization operon protein PhnA
B224_2420	ENOG410829K	Lysine exporter protein (Lyse ygga)
B224_2423	ENOG4105JAB	phenazine biosynthesis protein, phzf family
B224_2431	ENOG4105DUC	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division (By similarity)
B224_2433	ENOG4105DAH	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF (By similarity)
B224_2434	ENOG4105GHU	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid partitioning. Probably acts via its interaction with MukB and MukE. Overexpression results in anucleate cells. It has a calcium binding activity (By similarity)
B224_2436	ENOG4106371	Methyltransferase
B224_2437	ENOG4107S90	membrAne
B224_2440	ENOG4105CTQ	phosphohexokinase
B224_2443	ENOG4105CH2	amidohydrolase
B224_2444	ENOG4105PAD	Hydrolase
B224_2445	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
B224_2448	ENOG4105CPB	ATP-dependent endonuclease of the OLD family
B224_2449	ENOG4105ECQ	AraC Family Transcriptional Regulator
B224_2452	ENOG4105VP0	transcriptional regulator, lysR family
B224_2453	ENOG4105EJ9	Membrane
B224_2454	ENOG4106IUH	DTW domain containing protein
B224_2456	ENOG4105CPF	Cell wall formation (By similarity)
B224_2459	ENOG4105C1J	atp-dependent rna helicase
B224_2461	ENOG4105K5X	acetyltransferase
B224_2463	ENOG4105KK4	UPF0060 membrane protein
B224_2471	ENOG4105F2I	Transposase
B224_2476	ENOG4105CBN	LysR family transcriptional regulator
B224_2478	ENOG4105CHR	reductase
B224_2481	ENOG4105CS2	ec 3.2.1.21
B224_2482	ENOG4105DND	Transcriptional regulator
B224_2484	ENOG4105BZU	Histidine kinase
B224_2488	ENOG4107QKC	Oxidoreductase alpha (molybdopterin) subunit
B224_2489	ENOG4107H9G	Necessary for formate dehydrogenase activity (By similarity)
B224_2493	ENOG410642W	LysR family Transcriptional regulator
B224_2495	ENOG4107R5U	Periplasmic binding protein LacI transcriptional regulator
B224_2498	ENOG4107R5U	Periplasmic binding protein LacI transcriptional regulator
B224_2499	ENOG4105C2J	ABC transporter
B224_2501	ENOG4107R9N	ABC transporter
B224_2503	ENOG41062B0	ABC transporter, permease
B224_2505	ENOG4105F2I	Transposase
B224_2513	ENOG4105W5Q	DNA repair protein (RadC
B224_2520	ENOG4105CVR	type I restriction-modification system
B224_2523	ENOG4105HF0	Membrane
B224_2526	ENOG4105D5Q	Arginine ornithine antiporter
B224_2527	ENOG4105CHR	reductase
B224_2529	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
B224_2531	ENOG4105E39	Enoyl-CoA hydratase
B224_2533	ENOG4105E39	Enoyl-CoA hydratase
B224_2534	ENOG4105C1G	acyl-Coa dehydrogenase
B224_2535	ENOG4105C26	Dehydrogenase
B224_2537	ENOG4105C1G	acyl-Coa dehydrogenase
B224_2538	ENOG4107QX3	carboxylase
B224_2539	ENOG4105E39	Enoyl-CoA hydratase
B224_2543	ENOG4105CBH	Hydroxymethylglutaryl-CoA lyase
B224_2548	ENOG4106HK8	GPR1 FUN34 yaaH family protein
B224_2549	ENOG4105EXZ	Involved in the regulation of ptsG expression by binding and inactivating Mlc (By similarity)
B224_2551	ENOG4105BZG	amino acid carrier protein
B224_2553	ENOG41060WC	Enoyl-CoA hydratase
B224_2558	ENOG41062QD	Membrane
B224_2560	ENOG4107QN1	sodium solute
B224_2562	ENOG4105C5H	ABC transporter
B224_2564	ENOG4105EIN	peptidylprolyl cis-trans isomerase
B224_2565	ENOG4105K70	DNA-binding protein
B224_2567	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
B224_2568	ENOG4105CHN	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
B224_2569	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
B224_2571	ENOG4105DEA	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation
B224_2575	ENOG4105DK2	UPF0207 protein
B224_2576	ENOG4105D60	lipoprotein releasing system transmembrane protein
B224_2577	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
B224_2578	ENOG4105D60	lipoprotein releasing system transmembrane protein
B224_2583	ENOG4108JA2	transcriptioN-repair coupling factor
B224_2586	ENOG4105CZI	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
B224_2588	ENOG4108J59	Extracellular solute-binding protein, family 5
B224_2589	ENOG4108IPJ	Membrane
B224_2591	ENOG4108BY2	phosphohistidine phosphatase
B224_2593	ENOG4107QXK	peptidase
B224_2594	ENOG4105FQ6	thiopurine methyltransferase
B224_2596	ENOG4105F2I	Transposase
B224_2598	ENOG4105F2I	Transposase
B224_2600	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
B224_2602	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
B224_2611	ENOG4105C9C	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity)
B224_2615	ENOG4105DVS	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
B224_2619	ENOG4105D4P	Coproporphyrinogen iii oxidase
B224_2620	ENOG41090EK	ompa motb domain protein
B224_2621	ENOG4108KHX	Diguanylate cyclase
B224_2623	ENOG4108WS1	
B224_2627	ENOG41090A4	Pterin carbinolamine dehydratase
B224_2628	ENOG4105MIR	Phenylalanine 4-monooxygenase
B224_2630	ENOG4106K28	UPF0283 membrane protein
B224_2633	ENOG4105CM6	amino acid regulated cytosolic protein
B224_2635	ENOG4105YYT	phage shock protein B
B224_2637	ENOG41087YS	Phage shock protein A
B224_2638	ENOG4105E51	psp operon transcriptional activator
B224_2640	ENOG4108J59	Extracellular solute-binding protein, family 5
B224_2641	ENOG4108I5W	peptide transport system, permease protein
B224_2642	ENOG4108EU3	peptide transport system, permease
B224_2644	ENOG4108JQ3	Peptide ABC transporter ATP-binding protein
B224_2646	ENOG4108JQ2	peptide transport system atp-binding protein
B224_2648	ENOG4105FR9	TRNA-(Ms 2 io 6 A)-hydroxylase
B224_2649	ENOG4105DDV	Transcriptional regulator (LacI family
B224_2650	ENOG4105C5Y	PTS System
B224_2653	ENOG4105CS2	ec 3.2.1.21
B224_2654	ENOG4105CBA	glutamine phosphoribosylpyrophosphate amidotransferase
B224_2655	ENOG4105E96	Colicin v production protein
B224_2658	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
B224_2660	ENOG4105D1H	recombination factor protein RarA
B224_2661	ENOG4107Y7W	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) (By similarity)
B224_2663	ENOG4105CNU	cell division protein FtsK
B224_2664	ENOG4105EW9	transcriptional regulator AsnC family
B224_2665	ENOG4105DCF	alanine dehydrogenase
B224_2667	ENOG4105C3M	thioredoxin reductase
B224_2668	ENOG4105BZU	Histidine kinase
B224_2669	ENOG4107MBR	17 kDa surface antigen
B224_2670	ENOG4108R4Z	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine (By similarity)
B224_2671	ENOG4105DWA	May conjugate Arg from its aminoacyl-tRNA to the N- termini of proteins containing an N-terminal aspartate or glutamate
B224_2672	ENOG4105K9U	however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity)
B224_2673	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
B224_2674	ENOG4105KAE	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation (By similarity)
B224_2675	ENOG4105VEQ	Cold shock protein
B224_2676	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
B224_2679	ENOG4105KPY	Small multidrug resistance protein
B224_2682	ENOG4105DDY	UPF0142 protein ycaO
B224_2684	ENOG4105TMB	Formate nitrite transporter
B224_2686	ENOG4105C6N	Formate acetyltransferase
B224_2691	ENOG4105CH8	Succinyl-CoA ligase ADP-forming subunit alpha
B224_2693	ENOG4105CMV	Succinyl-CoA synthetase subunit beta
B224_2695	ENOG4105C7S	Dehydrogenase
B224_2698	ENOG4105C7P	2-oxoglutarate dehydrogenase, E1
B224_2699	ENOG4105E33	succinate dehydrogenase
B224_2700	ENOG4105C00	Succinate dehydrogenase (Flavoprotein subunit)
B224_2702	ENOG4105N1I	succinate dehydrogenase, hydrophobic membrane anchor protein
B224_2703	ENOG4108UTY	succinate dehydrogenase, cytochrome b556 subunit
B224_2705	ENOG4105BZN	citrate synthase
B224_2710	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
B224_2711	ENOG4105CWG	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34 (By similarity)
B224_2717	ENOG410600T	transposase
B224_2724	ENOG4105F5W	AtP-binding protein
B224_2725	ENOG4105D70	Integrase catalytic subunit
B224_2728	ENOG4105E14	MotA TolQ exbB proton channel
B224_2729	ENOG4105ER2	Ompa motb domain protein
B224_2733	ENOG4105KWU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
B224_2734	ENOG4105ES3	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
B224_2737	ENOG4105CQV	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
B224_2738	ENOG4105GKE	subunit e
B224_2740	ENOG4107QIZ	NADH dehydrogenase
B224_2741	ENOG4108IEH	NADH dehydrogenase subunit g
B224_2744	ENOG4105CMZ	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone (By similarity)
B224_2745	ENOG4105P3U	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
B224_2746	ENOG4107UFS	subunit j
B224_2747	ENOG41080EA	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
B224_2748	ENOG4105D65	subunit l
B224_2749	ENOG4105C8S	subunit m
B224_2751	ENOG4105CNR	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
B224_2753	ENOG4107QIK	phosphoribosylformylglycinamidine synthase
B224_2756	ENOG4105CHQ	Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella (By similarity)
B224_2760	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
B224_2762	ENOG4105CNE	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
B224_2764	ENOG4105N21	Membrane
B224_2765	ENOG4105CUT	histidyl-tRNA synthetase
B224_2767	ENOG4105C4E	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (By similarity)
B224_2769	ENOG4105HSZ	Cytoskeletal protein that is involved in cell-shape control through regulation of the length of the long axis (By similarity)
B224_2773	ENOG4105C55	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
B224_2774	ENOG4108UGX	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity)
B224_2775	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
B224_2778	ENOG4108ZIT	Ferredoxin, 2FE-2S
B224_2780	ENOG4105C9I	Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB
B224_2781	ENOG4108SWN	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA (By similarity)
B224_2783	ENOG4108Z4V	iron-sulfur cluster assembly
B224_2784	ENOG4107XTC	May be involved in the formation or repair of Fe-S clusters present in iron-sulfur proteins
B224_2785	ENOG4105C3J	Cysteine desulfurase
B224_2787	ENOG4108ZF1	Transcriptional regulator, BadM Rrf2 family
B224_2790	ENOG4105XPQ	lipid carrier protein
B224_2791	ENOG4105CFP	Peptidase U32
B224_2792	ENOG4106RZ4	Peptidase U32
B224_2795	ENOG4105M78	Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide (By similarity)
B224_2796	ENOG4107RAB	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
B224_2798	ENOG4107QN8	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
B224_2799	ENOG4105VIE	preprotein translocase, subunit YajC
B224_2801	ENOG4105C6U	Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity)
B224_2803	ENOG4105E2N	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) (By similarity)
B224_2805	ENOG4105W87	Cbs domain
B224_2807	ENOG4105D3R	alkyl hydroperoxide reductase
B224_2811	ENOG4108ISG	Major Facilitator
B224_2816	ENOG4105VT2	5-hydroxyisourate hydrolase
B224_2829	ENOG4105CBI	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
B224_2830	ENOG4105KE9	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity)
B224_2831	ENOG4105D43	The glycine cleavage system catalyzes the degradation of glycine (By similarity)
B224_2832	ENOG4105EAK	ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family
B224_2834	ENOG4105D0A	hydroxylase
B224_2836	ENOG4107YUN	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division (By similarity)
B224_2837	ENOG4105E5M	Multidrug resistance protein D
B224_2840	ENOG4105C3U	ABC transporter
B224_2841	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
B224_2842	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
B224_2845	ENOG4105CYM	Glutathione S-transferase
B224_2851	ENOG4105EIY	sodium-type flagellar protein motY
B224_2857	ENOG4105DH5	Responsible for the end-turnover of tRNA specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis (By similarity)
B224_2859	ENOG4105D3Y	Na H antiporter
B224_2863	ENOG4105EQ2	LysR family Transcriptional regulator
B224_2866	ENOG4105C1J	atp-dependent rna helicase
B224_2867	ENOG4105KA0	thioesterase Superfamily protein
B224_2871	ENOG4105CQB	FAD linked oxidase domain protein
B224_2873	ENOG4105EE5	Membrane protein terC
B224_2876	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
B224_2877	ENOG4105EKD	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism (By similarity)
B224_2878	ENOG4105D4U	had-superfamily hydrolase, subfamily iia
B224_2880	ENOG4105CAQ	asparagine synthetase
B224_2883	ENOG4108RXX	maleylacetoacetate isomerase
B224_2885	ENOG4105F1J	Homogentisate 1,2-dioxygenase
B224_2889	ENOG4105F1J	Homogentisate 1,2-dioxygenase
B224_2891	ENOG4105E6K	4-Hydroxyphenylpyruvate dioxygenase
B224_2893	ENOG4108W1A	pseudouridine synthase
B224_2896	ENOG4105BZU	Histidine kinase
B224_2899	ENOG4107RHT	methyl-accepting chemotaxis sensory transducer with Pas Pac sensor
B224_2901	ENOG4105CEY	Amp-dependent synthetase and ligase
B224_2907	ENOG4107SP2	The ortholog in A.thaliana is involved in photosystem II (PSII) assembly, but knockout of the corresponding gene in Synechoccus PCC 7002 has no effect on PSII activity
B224_2908	ENOG4105D25	secreted protein
B224_2914	ENOG4105HMI	Membrane
B224_2917	ENOG4108J8C	transporter major facilitator family protein
B224_2922	ENOG4105E2B	Taurine dioxygenase
B224_2923	ENOG4105EE6	Alcohol dehydrogenase zinc-binding domain protein
B224_2925	ENOG4105CR4	methylisocitrate lyase
B224_2927	ENOG4105BZN	citrate synthase
B224_2929	ENOG4108I0Z	Aconitate hydratase
B224_2931	ENOG4105C7F	AcnD-accessory protein PrpF
B224_2933	ENOG4108MN8	Membrane
B224_2935	ENOG4105EM2	membrane
B224_2937	ENOG4108Z0T	Part of a sulfur-relay system (By similarity)
B224_2938	ENOG4108S3P	Sporulation domain protein
B224_2940	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
B224_2941	ENOG4107QTG	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA (By similarity)
B224_2942	ENOG4105DI7	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity)
B224_2946	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
B224_2948	ENOG4105CJ0	Catalyzes the oxidation of erythronate-4-phosphate to 3- hydroxy-2-oxo-4-phosphonooxybutanoate (By similarity)
B224_2950	ENOG4105YVM	Phosphoesterase, PA-phosphatase related
B224_2951	ENOG4105D01	(LipO)protein
B224_2952	ENOG4105F2I	Transposase
B224_2956	ENOG4105DKW	ABC transporter
B224_2957	ENOG4105F5W	AtP-binding protein
B224_2958	ENOG4105D70	Integrase catalytic subunit
B224_2961	ENOG4105DKW	ABC transporter
B224_2963	ENOG4108HRN	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate (By similarity)
B224_2964	ENOG4105CF9	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation (By similarity)
B224_2967	ENOG4105C85	amino acid
B224_2978	ENOG4105C42	Type I secretion membrane fusion protein (HlyD
B224_2982	ENOG4105N5T	Radical SAM Protein
B224_2985	ENOG4105CBC	glutamate synthase
B224_2986	ENOG4105BZ8	glutamate synthase
B224_2989	ENOG4108Z4X	TRANSCRIPTIONal
B224_2997	ENOG4105C1J	atp-dependent rna helicase
B224_3004	ENOG4107QS8	(LipO)protein
B224_3007	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
B224_3009	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
B224_3011	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
B224_3013	ENOG4105DUK	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity)
B224_3017	ENOG4105MK2	5-formyltetrahydrofolate cyclo-ligase
B224_3018	ENOG4105E66	phosphoriboisomerase A
B224_3019	ENOG4108JQ1	Dehydrogenase
B224_3020	ENOG41080IJ	Diacylglycerol kinase
B224_3021	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
B224_3022	ENOG41080WI	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system (By similarity)
B224_3024	ENOG4108ESU	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Involved in the translocation of the substrate across the membrane (By similarity)
B224_3029	ENOG4105CZX	twitching motility protein
B224_3031	ENOG4107QQ4	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans (By similarity)
B224_3037	ENOG4108ZJT	translation initiation factor, Sui1
B224_3048	ENOG410620I	Diguanylate cyclase
B224_3051	ENOG410600T	transposase
B224_3052	ENOG4105F2I	Transposase
B224_3054	ENOG410600T	transposase
B224_3063	ENOG4105C8N	cysteinyl-tRNA synthetase
B224_3064	ENOG4108R5K	PPIases accelerate the folding of proteins (By similarity)
B224_3066	ENOG4105F10	Catalyzes the hydrolysis of the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1- phosphate (lipid X) and UMP (By similarity)
B224_3067	ENOG4105Y3U	Transglycosylase-associated protein
B224_3068	ENOG4108TGY	Glutathione S-transferase
B224_3073	ENOG4107R3N	Filamentation induced by cAMP protein fic
B224_3074	ENOG410600T	transposase
B224_3081	ENOG4105CII	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity)
B224_3082	ENOG4105WH1	Two component transcriptional regulator luxr family
B224_3084	ENOG4105CET	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria (By similarity)
B224_3085	ENOG4105W49	UPF0434 protein
B224_3087	ENOG4105CHD	Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) (By similarity)
B224_3088	ENOG4105BZ1	(ABC) transporter
B224_3089	ENOG4108EQH	DNA internalization-related competence protein ComEC Rec2
B224_3098	ENOG4105XEP	YhcH YjgK YiaL family protein
B224_3102	ENOG4105D9U	N-acetyltransferase
B224_3110	ENOG4108SAU	DNA-binding protein H-ns
B224_3112	ENOG4105CFG	Acts as a chaperone (By similarity)
B224_3113	ENOG4105W5Q	DNA repair protein (RadC
B224_3116	ENOG4105D70	Integrase catalytic subunit
B224_3121	ENOG4105F5W	AtP-binding protein
B224_3124	ENOG4108YX2	DNA-binding protein
B224_3129	ENOG4105DZR	Type I site-specific deoxyribonuclease
B224_3142	ENOG4105D7V	transposase
B224_3161	ENOG4108EQH	DNA internalization-related competence protein ComEC Rec2
B224_3169	ENOG4105D7A	ATP-binding protein
B224_3173	ENOG4105CGF	Aromatic amino acid aminotransferase
B224_3176	ENOG4105QMY	Porin Gram-negative type
B224_3179	ENOG4105DVT	helicase
B224_3181	ENOG4105DGU	Histone deacetylase
B224_3182	ENOG4108ISG	Major Facilitator
B224_3183	ENOG4105C9W	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity (By similarity)
B224_3185	ENOG4105G6Z	alkaline phosphatase
B224_3192	ENOG4105NXH	GreA GreB family elongation factor
B224_3193	ENOG4108KX4	response regulator
B224_3194	ENOG4105BZU	Histidine kinase
B224_3195	ENOG4105CXY	transporter
B224_3198	ENOG4105D7V	transposase
B224_3200	ENOG4106TNF	Periplasmic binding protein
B224_3201	ENOG4105E5Q	amino acid AbC transporter
B224_3202	ENOG4105CDA	abc transporter atp-binding protein
B224_3205	ENOG4105VNT	transposase (IS4 family) protein
B224_3208	ENOG4105D5Q	Arginine ornithine antiporter
B224_3212	ENOG4105C37	(CBS) domain
B224_3215	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
B224_3216	ENOG4105E2Z	phosphate ABC transporter (Permease
B224_3219	ENOG4105C8U	phosphate abc transporter
B224_3221	ENOG4108Z6B	deaminase
B224_3223	ENOG4107QP3	malate synthase g
B224_3225	ENOG4108I9X	Isocitrate lyase
B224_3229	ENOG4105CZ5	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate (By similarity)
B224_3230	ENOG4105CXB	phosphoribosylaminoimidazole synthetase
B224_3231	ENOG4108V3E	phosphoribosylglycinamide formyltransferase
B224_3232	ENOG4107QNR	UPF0135 protein
B224_3234	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
B224_3236	ENOG4105BZU	Histidine kinase
B224_3237	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
B224_3240	ENOG4105RH4	Glycine cleavage system transcriptional repressor
B224_3242	ENOG4105CUU	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) (By similarity)
B224_3244	ENOG4105C9X	ppx gppa phosphatase
B224_3246	ENOG4105CJW	magnesium transporter
B224_3247	ENOG4105D7V	transposase
B224_3248	ENOG4105CJW	magnesium transporter
B224_3254	ENOG4108ZW7	flagellar rod assembly protein muramidase flgj
B224_3257	ENOG4105D92	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity)
B224_3258	ENOG4107W7W	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity)
B224_3259	ENOG4105CGA	flagellar basal-body rod protein FlgG
B224_3260	ENOG4108KPB	Flagellar basal-body rod protein FlgF
B224_3261	ENOG4105BZE	flagellar hook protein, FlgE
B224_3263	ENOG4108ZC9	flagellar basal-body rod protein flgc
B224_3264	ENOG4105K88	Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body (By similarity)
B224_3265	ENOG4105BZU	Histidine kinase
B224_3266	ENOG4107R88	Chemotaxis protein (CheV)
B224_3267	ENOG4107ESN	Flagella basal body P-ring formation protein flgA
B224_3271	ENOG4108RE9	Phosphodiesterase
B224_3273	ENOG4107QSI	ABC, transporter
B224_3275	ENOG4105I08	Pseudouridine synthase
B224_3277	ENOG4105D7V	transposase
B224_3280	ENOG4108594	Permease of the drug metabolite transporter
B224_3287	ENOG4105VEQ	Cold shock protein
B224_3290	ENOG4107QSN	dihydrolipoamide acetyltransferase
B224_3291	ENOG4105CPP	Dehydrogenase, E1 component
B224_3292	ENOG4107RUY	(E1 component), alpha subunit
B224_3296	ENOG4105KR1	Trans-acting protein required for termination of DNA replication. Binds to DNA replication terminator sequences (terA to terF) to prevent the passage of replication forks. The termination efficiency will be affected by the affinity of this protein for the terminator sequence (By similarity)
B224_3299	ENOG4108YXG	UPF0502 protein
B224_3303	ENOG4105E3R	(LipO)protein
B224_3304	ENOG4108Q9C	Periplasmic Protein
B224_3310	ENOG4105D75	Capsular exopolysaccharide family
B224_3311	ENOG4107ZF2	Phosphatase
B224_3312	ENOG4105DAY	polysaccharide export protein
B224_3319	ENOG4105F2I	Transposase
B224_3329	ENOG4108I19	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis (By similarity)
B224_3331	ENOG4105DBZ	Dtdp-4-dehydrorhamnose reductase
B224_3333	ENOG4105C1B	dTDP-glucose 4-6-dehydratase
B224_3334	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
B224_3338	ENOG4106KNT	transcriptional regulator
B224_3339	ENOG4105CA9	Pyruvate kinase
B224_3343	ENOG4105BZS	acriflavin resistance protein
B224_3345	ENOG4107QPN	acyl-Coa dehydrogenase
B224_3348	ENOG4107SSZ	Phosphatase
B224_3350	ENOG4105F2I	Transposase
B224_3351	ENOG410600T	transposase
B224_3355	ENOG4105F5W	AtP-binding protein
B224_3356	ENOG4105D70	Integrase catalytic subunit
B224_3359	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
B224_3362	ENOG4105BZS	acriflavin resistance protein
B224_3363	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
B224_3366	ENOG4108IG5	Transcriptional regulator
B224_3370	ENOG4105C29	acyl-CoA thioesterase
B224_3371	ENOG4105FE9	pseudouridine synthase
B224_3372	ENOG4105K8I	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves (By similarity)
B224_3374	ENOG4107RTD	sua5 ycio yrdc ywlc family protein
B224_3375	ENOG4105DB7	PHP domain protein
B224_3377	ENOG4105CRQ	synthase (Component I)
B224_3378	ENOG4108EFP	Anthranilate synthase component II
B224_3380	ENOG4108I0Q	anthranilate phosphoribosyltransferase
B224_3381	ENOG4105DK0	Indole-3-glycerol phosphate synthase
B224_3383	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
B224_3384	ENOG4105F6H	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate (By similarity)
B224_3396	ENOG4105C3Y	UTP-glucose-1-phosphate uridylyltransferase
B224_3397	ENOG4105C1B	dTDP-glucose 4-6-dehydratase
B224_3398	ENOG4105DBZ	Dtdp-4-dehydrorhamnose reductase
B224_3402	ENOG4105E12	capsule polysaccharide
B224_3404	ENOG41084CK	capsule polysaccharide
B224_3405	ENOG4106YG3	ABC transporter
B224_3406	ENOG4105DSP	amino acid AbC transporter
B224_3407	ENOG4106PMH	Extracellular solute-binding protein family 3
B224_3408	ENOG4108JEH	abc transporter atp-binding protein
B224_3411	ENOG4105DWU	Membrane
B224_3414	ENOG4105VNT	transposase (IS4 family) protein
B224_3415	ENOG4105D7V	transposase
B224_3417	ENOG4105K89	arsenate reductase
B224_3420	ENOG4105ERG	peptidase m48, ste24p
B224_3427	ENOG4105D7V	transposase
B224_3429	ENOG4105CSR	polyphosphate kinase 2
B224_3432	ENOG4108IJ9	(ABC) transporter
B224_3433	ENOG4105EG2	ABC transporter, permease
B224_3435	ENOG4105D56	permease protein
B224_3437	ENOG4107FKK	extracellular solute-binding protein family 1
B224_3438	ENOG4106V8H	Nucleoid-associated protein
B224_3439	ENOG4105PAN	UPF0352 protein
B224_3440	ENOG4105E68	Sulfatase
B224_3443	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
B224_3444	ENOG4105CUG	Oligopeptidase b
B224_3452	ENOG4108QSZ	General inhibitor of pancreatic serine proteases inhibits chymotrypsin, trypsin, elastases, factor X, kallikrein as well as a variety of other proteases (By similarity)
B224_3453	ENOG4108WFC	UPF0438 protein yifE
B224_3460	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
B224_3461	ENOG4106MZZ	glycerophosphoryl diester phosphodiesterase
B224_3463	ENOG4105C6V	Glycerol-3-phosphate dehydrogenase
B224_3465	ENOG4105E98	transcriptional regulator DeoR family
B224_3466	ENOG4105CXY	transporter
B224_3468	ENOG410600T	transposase
B224_3470	ENOG4105D8C	Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity)
B224_3473	ENOG4108JQ0	Key enzyme in the regulation of glycerol uptake and metabolism (By similarity)
B224_3474	ENOG4105HEI	LysR family (Transcriptional regulator
B224_3482	ENOG4105CV8	reductase
B224_3484	ENOG4105F27	Major Facilitator
B224_3486	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
B224_3488	ENOG4105C4M	(Ubiquinol oxidase) subunit I
B224_3489	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
B224_3492	ENOG4105DU6	RNA polymerase
B224_3497	ENOG4108Q2J	Inner membrane protein YebE
B224_3503	ENOG4106428	Protein of unknown function (DUF2496)
B224_3505	ENOG4105JQN	Transcriptional regulator
B224_3511	ENOG4105FE9	pseudouridine synthase
B224_3512	ENOG4105D82	Glutamate dehydrogenase
B224_3519	ENOG4105CFI	type iii restriction protein res subunit
B224_3522	ENOG4105BZU	Histidine kinase
B224_3529	ENOG4105DP5	Catalyzes the biosynthesis of agmatine from arginine (By similarity)
B224_3533	ENOG4105D42	Cleaves the N-terminal amino acid of tripeptides (By similarity)
B224_3538	ENOG4105D7V	transposase
B224_3540	ENOG4105C3E	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine (By similarity)
B224_3542	ENOG4108YYC	ycei family
B224_3544	ENOG4105CC0	LysR family Transcriptional regulator
B224_3547	ENOG4105CKU	formyltetrahydrofolate synthetase
B224_3550	ENOG4105C8Q	Methyl-accepting chemotaxis
B224_3551	ENOG4105EUJ	GTP cyclohydrolase i
B224_3552	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
B224_3555	ENOG4105D06	uba thif-type nad fad binding protein
B224_3557	ENOG4105D3C	The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters (By similarity)
B224_3559	ENOG4105CGB	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system (By similarity)
B224_3560	ENOG4105E0C	molybdate abc transporter
B224_3561	ENOG4108S6J	ABC transporter, periplasmic molybdate-binding protein
B224_3562	ENOG4108ZAF	Molybdopterin
B224_3563	ENOG4105M00	molybdopterin converting factor, subunit 1
B224_3564	ENOG4108YXW	Together with MoaA, is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
B224_3566	ENOG4108RIR	Molybdenum cofactor biosynthesis protein
B224_3567	ENOG4105CUW	cytochrome C-TYPE protein
B224_3570	ENOG4105GXZ	Ferredoxin-type protein NapH
B224_3571	ENOG4108BGM	Quinol dehydrogenase periplasmic component
B224_3573	ENOG4107QIW	Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity)
B224_3577	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
B224_3579	ENOG4105BZU	Histidine kinase
B224_3580	ENOG4105WH1	Two component transcriptional regulator luxr family
B224_3584	ENOG4105BZU	Histidine kinase
B224_3588	ENOG4105CHW	UPF0052 protein
B224_3590	ENOG4105E7A	Glutamine amidotransferase
B224_3591	ENOG4105F55	Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate (By similarity)
B224_3593	ENOG4107QPN	acyl-Coa dehydrogenase
B224_3595	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
B224_3598	ENOG4107RZZ	dna polymerase iii epsilon subunit
B224_3600	ENOG4108UMW	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
B224_3601	ENOG4105D1A	Methyltransferase
B224_3602	ENOG4108RW0	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
B224_3603	ENOG4105E9H	Lytic Murein transglycosylase
B224_3607	ENOG4105NAU	thioesterase Superfamily protein
B224_3609	ENOG41060NJ	transcriptional regulator
B224_3611	ENOG4107SC1	transglycosylase
B224_3616	ENOG4108WPH	sigma 54 modulation protein ribosomal protein S30EA
B224_3623	ENOG4105CFU	surface antigen
B224_3625	ENOG4105KQ5	peptidylprolyl cis-trans isomerase
B224_3627	ENOG4107ZN8	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity (By similarity)
B224_3631	ENOG4105VNH	ABC transporter solute-binding protein
B224_3634	ENOG4108VGW	abc transporter atp-binding protein
B224_3635	ENOG4108T9J	Cdp-alcohol phosphatidyltransferase
B224_3637	ENOG4105CVE	Lytic murein transglycosylase
B224_3639	ENOG41090MY	MarR family Transcriptional regulator
B224_3643	ENOG4107QIX	Phosphoglucomutase (EC 5.4.2.2
B224_3644	ENOG4107CDU	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated (By similarity)
B224_3645	ENOG4105EV9	Alpha Beta Hydrolase
B224_3647	ENOG4105NNH	LexA regulated protein
B224_3648	ENOG4105MHQ	Low-potential electron donor to a number of redox enzymes (By similarity)
B224_3650	ENOG41090R7	Ferric uptake
B224_3651	ENOG4105CX6	glutaminyL-tRNA synthetase
B224_3655	ENOG4105E2D	ec 3.2.1.52
B224_3656	ENOG4105CI1	PTS System
B224_3657	ENOG4105CKA	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion (By similarity)
B224_3659	ENOG4105CE4	GlcNAc 6-P deacetylase
B224_3660	ENOG4105E2R	ROK family
B224_3662	ENOG4105DIJ	Phosphoethanolamine transferase
B224_3663	ENOG4105CDY	transcriptional regulatory protein
B224_3665	ENOG4105C9M	aspartyl-trna synthetase
B224_3666	ENOG41081XQ	Conserved Protein
B224_3667	ENOG4105DA6	Catalyzes the conversion of 5-methoxyuridine (mo5U) to uridine-5-oxyacetic acid (cmo5U) at position 34 in tRNA. May also participate in the methylation of uridine-5-oxyacetic acid (cmo5U) to uridine-5-oxyacetic acid methyl ester (mcmo5U) (By similarity)
B224_3668	ENOG4105PFA	Catalyzes the conversion of 5-hydroxyuridine (ho5U) to 5-methoxyuridine (mo5U) at position 34 in tRNA (By similarity)
B224_3673	ENOG4105C5Q	Transcriptional regulator
B224_3674	ENOG4107TT5	NLP P60 protein
B224_3676	ENOG4107RGH	Aldehyde dehydrogenase
B224_3678	ENOG4108RZE	Tetr family transcriptional regulator
B224_3681	ENOG4105C6T	cysteine synthase
B224_3686	ENOG4105UQX	Mate efflux family protein
B224_3689	ENOG4105Z2P	Protein of unknown function (DUF465)
B224_3690	ENOG4105D95	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin (By similarity)
B224_3694	ENOG4105QVC	MOSC domain-containing protein
B224_3694	ENOG4105QVC	MOSC domain-containing protein
B224_3696	ENOG4105D0M	Protease HtpX homolog
B224_3697	ENOG4105E78	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity)
B224_3698	ENOG410626R	Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity)
B224_3699	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
B224_3702	ENOG4105CZF	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism (By similarity)
B224_3703	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
B224_3708	ENOG4105C5S	asparaginyl-tRNA synthetase
B224_3710	ENOG4105DS2	Anaerobic c4-dicarboxylate transporter
B224_3716	ENOG4105KUZ	arsenate reductase
B224_3717	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
B224_3723	ENOG4105C3N	Participates in control of cell volume in low-osmolarity conditions (By similarity)
B224_3728	ENOG410829K	Lysine exporter protein (Lyse ygga)
B224_3730	ENOG4105RX8	Protein of unknown function (DUF1523)
B224_3733	ENOG4105DU0	nucleoside hydrolase
B224_3734	ENOG4105D3G	Pseudouridine synthase
B224_3735	ENOG4107SXA	Phosphorylase
B224_3737	ENOG4105YRI	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
B224_3738	ENOG4105K4T	epimerase
B224_3739	ENOG4105VDB	UPF0125 protein
B224_3741	ENOG4108Z1B	Cyclase dehydrase
B224_3742	ENOG4108UH4	Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity)
B224_3743	ENOG4105DFP	Integrase
B224_3750	ENOG4105PF0	Antitoxin component of a toxin-antitoxin (TA) module. Functions as an mRNA interferase antitoxin
B224_3752	ENOG4105CVR	type I restriction-modification system
B224_3758	ENOG4108YYD	acetyltransferase
B224_3769	ENOG4108YYX	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. Modulates RNA-binding and helicase activities of the degradosome (By similarity)
B224_3772	ENOG41065U4	response regulator
B224_3775	ENOG4108JJ9	ABC, transporter
B224_3778	ENOG4108JJ8	(ABC) transporter
B224_3782	ENOG4108R96	Methyltransferase, YaeB family
B224_3788	ENOG4105C6T	cysteine synthase
B224_3789	ENOG4105KZ7	phosphocarrier protein hpr
B224_3792	ENOG4105C5Y	PTS System
B224_3793	ENOG4108VKM	cytochrome b561
B224_3796	ENOG4105EYH	Exonuclease
B224_3798	ENOG4107RH8	nuclease SbcCD subunit D
B224_3799	ENOG4105K5X	acetyltransferase
B224_3801	ENOG4105DH7	May be involved in recombination (By similarity)
B224_3803	ENOG4108UJV	acyl-CoA thioesterase i
B224_3804	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
B224_3808	ENOG4105CJP	fad dependent oxidoreductase
B224_3809	ENOG4107VRI	Transcriptional regulator
B224_3811	ENOG4105C26	Dehydrogenase
B224_3813	ENOG4108JPW	Aminotransferase
B224_3816	ENOG4105CUB	amino acid
B224_3818	ENOG4105CUB	amino acid
B224_3823	ENOG4108V1T	peptidylprolyl cis-trans isomerase
B224_3824	ENOG4105C8E	extradiol ring-cleavage dioxygenase class IIi protein subunit b
B224_3827	ENOG4105BZU	Histidine kinase
B224_3830	ENOG4105XIQ	Protein of unknown function (DUF2517)
B224_3835	ENOG4105BZU	Histidine kinase
B224_3838	ENOG4105EQ2	LysR family Transcriptional regulator
B224_3839	ENOG4105ENX	hydrolase
B224_3842	ENOG4107RTG	Major Facilitator superfamily
B224_3847	ENOG4105WKS	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity)
B224_3850	ENOG4108T0W	nitrous oxide maturation protein NosY
B224_3851	ENOG4105CIG	ABC transporter
B224_3861	ENOG410600T	transposase
B224_3864	ENOG4107N1Q	ErfK YbiS YcfS YnhG family protein
B224_3869	ENOG4105EBA	Specifically methylates the adenine in position 1618 of 23S rRNA (By similarity)
B224_3870	ENOG4107TT5	NLP P60 protein
B224_3871	ENOG4107YAK	holo-(acyl carrier protein) synthase 2
B224_3873	ENOG4107QR8	Thioredoxin
B224_3875	ENOG4105C66	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity)
B224_3876	ENOG4105CIY	formyltetrahydrofolate deformylase
B224_3885	ENOG4105E4C	Lytic transglycosylase catalytic
B224_3888	ENOG4105NHU	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group (By similarity)
B224_3889	ENOG4105EP9	oxidoreductase
B224_3898	ENOG4105CCT	upf0313 protein
B224_3900	ENOG4105BZS	acriflavin resistance protein
B224_3903	ENOG4105BZU	Histidine kinase
B224_3904	ENOG4105D78	K07001 NTE family protein
B224_3906	ENOG4105C8J	)-transporter
B224_3911	ENOG4105UYK	outer membrane protein a
B224_3913	ENOG4105UYK	outer membrane protein a
B224_3915	ENOG4105UYK	outer membrane protein a
B224_3918	ENOG4107R1I	NAD-dependent malic enzyme
B224_3919	ENOG4105ECQ	AraC Family Transcriptional Regulator
B224_3921	ENOG4105UQX	Mate efflux family protein
B224_3923	ENOG4105RKX	Protein of unknown function (DUF2498)
B224_3925	ENOG4105BZU	Histidine kinase
B224_3926	ENOG4105C2W	permease
B224_3928	ENOG4108KMH	lipoate-protein ligase a
B224_3930	ENOG4105BZG	amino acid carrier protein
B224_3936	ENOG4105PTV	Nudix Hydrolase
B224_3938	ENOG4105CDA	abc transporter atp-binding protein
B224_3939	ENOG4105DRP	amino acid AbC transporter
B224_3944	ENOG4105EZ7	amino acid ABC transporter
B224_3949	ENOG4105CJ1	ABC, transporter
B224_3950	ENOG4108V1T	peptidylprolyl cis-trans isomerase
B224_3952	ENOG4106N3A	copper homeostasis protein cutc
B224_3956	ENOG4105ERG	peptidase m48, ste24p
B224_3960	ENOG4105BZU	Histidine kinase
B224_3961	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
B224_3962	ENOG4108ZI4	Glyoxalase Bleomycin resistance protein (Dioxygenase
B224_3964	ENOG4105BZU	Histidine kinase
B224_3966	ENOG4108JU9	GAF modulated sigma54 specific transcriptional regulator Fis family
B224_3968	ENOG4105C26	Dehydrogenase
B224_3971	ENOG4108IPJ	Membrane
B224_3973	ENOG4106YYS	transcriptional regulatory protein
B224_3976	ENOG4105CEQ	signal transduction histidine kinase regulating citrate malate metabolism
B224_3977	ENOG4107R1I	NAD-dependent malic enzyme
B224_3981	ENOG4105J12	Multidrug resistance protein mdtN
B224_3989	ENOG4108RDD	Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine (By similarity)
B224_3991	ENOG4105CJD	(Anaerobic) ribonucleoside-triphosphate reductase
B224_3995	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
B224_3996	ENOG4107NPY	receptor for the septal ring structure, may anchor it to the inner-membrane (By similarity)
B224_3997	ENOG4105CDB	Required for chromosome condensation and partitioning (By similarity)
B224_3998	ENOG4105EXN	Sulfate transport protein CysZ
B224_3999	ENOG4105EN6	Membrane
B224_4003	ENOG4105EAQ	(twin-arginine translocation) pathway signal
B224_4004	ENOG4105DIT	ErfK YbiS YcfS YnhG family protein
B224_4013	ENOG4107T9C	Alpha amylase catalytic region
B224_4025	ENOG4105BZU	Histidine kinase
B224_4026	ENOG4105D3U	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
B224_4027	ENOG4105C9K	Endothelin-converting enzyme 1
B224_4030	ENOG4105C5H	ABC transporter
B224_4035	ENOG4105DVH	amino acid
B224_4036	ENOG4105C44	Serine transporter
B224_4038	ENOG410642W	LysR family Transcriptional regulator
B224_4040	ENOG4105VNT	transposase (IS4 family) protein
B224_4041	ENOG4107QM9	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA (By similarity)
B224_4044	ENOG4105C0B	DNA polymerase III (alpha subunit)
B224_4045	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
B224_4047	ENOG4105D0V	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
B224_4048	ENOG4105DAF	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
B224_4049	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
B224_4050	ENOG4105D7M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
B224_4053	ENOG4108RFI	Molecular chaperone that interacts specifically with outer membrane proteins, thus maintaining the solubility of early folding intermediates during passage through the periplasm (By similarity)
B224_4056	ENOG4105DZP	Membrane-associated zinc metalloprotease
B224_4058	ENOG4105CEA	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity)
B224_4059	ENOG4105KNE	Phosphatidate cytidylyltransferase
B224_4060	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
B224_4061	ENOG4108VCV	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity)
B224_4062	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
B224_4064	ENOG4105CU7	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity)
B224_4065	ENOG4105CE9	30S ribosomal protein S2
B224_4066	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
B224_4068	ENOG4105E1P	Modifies, by uridylylation or deuridylylation the PII (GlnB) regulatory protein (By similarity)
B224_4070	ENOG4105DMJ	Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate (By similarity)
B224_4071	ENOG4108T8E	UPF0325 protein
B224_4073	ENOG4105CI1	PTS System
B224_4074	ENOG4107W52	maltose operon periplasmic protein
B224_4076	ENOG4105QDK	Flavodoxin
B224_4077	ENOG4105DR9	pseudouridine synthase
B224_4078	ENOG4105WP7	tRNA pseudouridine synthase C
B224_4084	ENOG4105EXF	Zn-ribbon-containing, possibly nucleic-acid-binding protein
B224_4086	ENOG4108T6E	Interacts with the SecY protein in vivo. May bind preferentially to an uncomplexed state of SecY, thus functioning either as a chelating agent for excess SecY in the cell or as a regulatory factor that negatively controls the translocase function (By similarity)
B224_4087	ENOG4107R1K	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) (By similarity)
B224_4092	ENOG4105BZU	Histidine kinase
B224_4093	ENOG4105EWT	decarboxylase family
B224_4094	ENOG4105CIQ	May have a role in processing of nucleic acids. It is probably not an exonuclease
B224_4096	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
B224_4098	ENOG4105EZ6	Catalyzes the 2'-O-methylation at nucleotide C2498 in 23S rRNA (By similarity)
B224_4100	ENOG4105M08	Membrane
B224_4102	ENOG4105ETT	transcriptional Regulator, LysR family
B224_4104	ENOG4105C8Q	Methyl-accepting chemotaxis
B224_4105	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
B224_4108	ENOG4105CJ2	(LipO)protein
B224_4109	ENOG4105D26	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. The first step is catalyzed by NqrF, which accepts electrons from NADH and reduces ubiquinone-1 to ubisemiquinone by a one-electron transfer pathway (By similarity)
B224_4112	ENOG4108IUB	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
B224_4114	ENOG4105F5D	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
B224_4116	ENOG4106I92	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
B224_4117	ENOG4108J5C	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
B224_4119	ENOG4105DWQ	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
B224_4121	ENOG4105M85	Bola protein
B224_4122	ENOG4105D8J	Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle (By similarity)
B224_4125	ENOG4108R5K	PPIases accelerate the folding of proteins (By similarity)
B224_4128	ENOG4105EYM	Major Facilitator superfamily
B224_4129	ENOG4105DRB	nucleoside-specific channel-forming protein
B224_4131	ENOG4108VPT	UPF0234 protein
B224_4132	ENOG4108JZF	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity)
B224_4133	ENOG4107S0N	DJ-1 family
B224_4136	ENOG4105F2I	Transposase
B224_4144	ENOG4105CS6	Rhs element vgr protein
B224_4145	ENOG4108WC9	type VI secretion system effector, hcp1 family
B224_4148	ENOG4105VJY	transcriptional regulator
B224_4149	ENOG4105CHH	sulfate transporter
B224_4158	ENOG4105K89	arsenate reductase
B224_4160	ENOG4105D6J	arsenicaL-resistance protein
B224_4163	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
B224_4167	ENOG4105CMR	udp-glucose 4-epimerase
B224_4168	ENOG4105CJJ	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity)
B224_4169	ENOG4105EJ7	Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O (By similarity)
B224_4171	ENOG4108RMU	ferritin dps family protein
B224_4178	ENOG4105CV9	cyclopropane-fatty-acyl-phospholipid synthase
B224_4182	ENOG4107FW0	short-chain dehydrogenase reductase
B224_4184	ENOG4105CVP	deoxyribo-dipyrimidine photolyase
B224_4186	ENOG4108XDN	Transcriptional regulator
B224_4187	ENOG4107SEY	Conserved Protein
B224_4194	ENOG4105CQC	Prephenate dehydratase
B224_4201	ENOG4108KDD	Involved in the transport of maltose and maltodextrins (By similarity)
B224_4202	ENOG410600T	transposase
B224_4205	ENOG410600T	transposase
B224_4207	ENOG4105CUK	Alpha-N-arabinofuranosidase (EC 3.2.1.55)
B224_4212	ENOG4105F0P	binding-protein-dependent transport systems inner membrane Component
B224_4222	ENOG4105D8V	Glucose sorbosone dehydrogenase
B224_4224	ENOG4105MVE	transcriptional regulator
B224_4226	ENOG4105G63	Type III effector Hrp-dependent
B224_4227	ENOG4105FB2	class II Aldolase
B224_4228	ENOG4105QG4	Catalyzes the reversible isomerization between hydroxypyruvate and 2-hydroxy-3-oxopropanoate (also termed tartronate semialdehyde) (By similarity)
B224_4230	ENOG4105EXW	epimerase dehydratase
B224_4232	ENOG4105C6Z	Gluconate
B224_4234	ENOG4108W2P	Methyl-accepting chemotaxis
B224_4237	ENOG4105E1F	short-chain dehydrogenase reductase
B224_4242	ENOG4105CTD	carboxy-peptidase
B224_4247	ENOG4105XDF	Protein of unknown function (DUF1272)
B224_4249	ENOG4105CFP	Peptidase U32
B224_4252	ENOG4105N14	lysine exporter protein LysE YggA
B224_4256	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
B224_4258	ENOG4108NJZ	Sensory box GGDEF EAL domain protein
B224_4263	ENOG4105DB1	molybdopterin oxidoreductase
B224_4265	ENOG4106WHD	Tetrathionate reductase
B224_4266	ENOG4105QA4	4Fe-4S Ferredoxin, iron-sulfur binding domain protein
B224_4268	ENOG4108ZXC	Two component transcriptional regulator, luxr family
B224_4269	ENOG4105EQ6	Hydrolyzes dipeptides containing N-terminal aspartate residues. May play a role in allowing the cell to use peptide aspartate to spare carbon otherwise required for the synthesis of the aspartate family of amino acids (By similarity)
B224_4276	ENOG4105C26	Dehydrogenase
B224_4279	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
B224_4280	ENOG4105CDU	Replicative dna helicase
B224_4285	ENOG4105CGH	5'-nucleotidase
B224_4290	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
B224_4291	ENOG4108V1T	peptidylprolyl cis-trans isomerase
B224_4293	ENOG4105VRX	Protein slyX homolog
B224_4294	ENOG4108YZY	peptidylprolyl cis-trans isomerase
B224_4296	ENOG4105VKU	nucleicacid-binding protein
B224_4298	ENOG4107R88	Chemotaxis protein (CheV)
B224_4300	ENOG4105DNZ	Alpha Beta Hydrolase
B224_4305	ENOG4105YP7	UPF0270 protein
B224_4306	ENOG4105CJE	phosphoribulokinase (EC 2.7.1.19)
B224_4309	ENOG4108UKZ	OsmC family
B224_4310	ENOG4107RYR	Transcriptional regulator, Crp Fnr family
B224_4314	ENOG4108MA4	Peptidase M66
B224_4318	ENOG4105BZU	Histidine kinase
B224_4320	ENOG4105D8G	Major Facilitator superfamily
B224_4334	ENOG4105PYN	Pyridoxamine 5-phosphate oxidase-related
B224_4335	ENOG41090JE	Utilization Protein
B224_4337	ENOG4105EHG	Permease protein
B224_4341	ENOG4105C6Y	Udp-glucose 6-dehydrogenase
B224_4345	ENOG4105SA9	Catalyzes the transfer of the L-Ara4N moiety of the glycolipid undecaprenyl phosphate-alpha-L-Ara4N to lipid A. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides (By similarity)
B224_4348	ENOG4105CKK	Glycosyl transferase, family 2
B224_4350	ENOG4105E4C	Lytic transglycosylase catalytic
B224_4352	ENOG4105C5H	ABC transporter
B224_4355	ENOG4105C7N	Xanthine uracil vitamin C permease
B224_4357	ENOG41066UG	Regulatory DnaK co-chaperone. Direct interaction between DnaK and DjlA is needed for the induction of the wcaABCDE operon, involved in the synthesis of a colanic acid polysaccharide capsule, possibly through activation of the RcsB RcsC phosphotransfer signaling pathway. The colanic acid capsule may help the bacterium survive conditions outside the host (By similarity)
B224_4359	ENOG4108S0S	Nucleotidyl transferase
B224_4360	ENOG4105EHM	Aminoglycoside phosphotransferase
B224_4361	ENOG4105E7H	involved in the assembly of LPS in the outer leaflet of the outer membrane. Determines N-hexane tolerance and is involved in outer membrane permeability. Essential for envelope biogenesis (By similarity)
B224_4365	ENOG4105CEZ	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) (By similarity)
B224_4366	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
B224_4367	ENOG4105NWN	ApaG protein
B224_4368	ENOG4105DDT	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP (By similarity)
B224_4371	ENOG4105DEN	Luciferase family
B224_4373	ENOG4108ESY	Metal dependent phosphohydrolase
B224_4375	ENOG4105DWD	nucleoside recognition domain protein
B224_4377	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
B224_4378	ENOG4105KK9	This protein binds to 23S rRNA in the presence of protein L20 (By similarity)
B224_4379	ENOG4105EAH	synthase
B224_4381	ENOG4105EPW	hflc protein
B224_4383	ENOG4107QJR	hflk protein
B224_4384	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
B224_4385	ENOG4105KW8	RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity)
B224_4387	ENOG4105DKX	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity)
B224_4389	ENOG4105DC6	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity)
B224_4391	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
B224_4392	ENOG4105K8N	protein family UPF0079, ATPase
B224_4393	ENOG4105DR1	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)
B224_4400	ENOG4108JEI	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity)
B224_4402	ENOG4108UMI	ABC transporter, permease
B224_4404	ENOG4105D01	(LipO)protein
B224_4407	ENOG4105MDZ	Transcriptional activator rfaH
B224_4409	ENOG4105C8Q	Methyl-accepting chemotaxis
B224_4410	ENOG4105BZU	Histidine kinase
B224_4412	ENOG4105BZU	Histidine kinase
B224_4421	ENOG4105BZU	Histidine kinase
B224_4423	ENOG4105C4Q	deoxyguanosinetriphosphate triphosphohydrolase-like protein
B224_4424	ENOG4105BZU	Histidine kinase
B224_4431	ENOG4105EXG	Transcriptional regulator
B224_4436	ENOG4107QWK	SAICAR synthetase
B224_4438	ENOG4107EG0	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
B224_4440	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
B224_4442	ENOG4105RH4	Glycine cleavage system transcriptional repressor
B224_4443	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
B224_4446	ENOG4105XWI	UPF0304 protein
B224_4449	ENOG4105C6H	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity)
B224_4452	ENOG4105C6K	Malic enzyme
B224_4453	ENOG4108ZP8	Acetolactate synthase small subunit
B224_4455	ENOG4105C7K	acetolactate synthase
B224_4458	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
B224_4459	ENOG4105YVM	Phosphoesterase, PA-phosphatase related
B224_4462	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
B224_4464	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
B224_4466	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
B224_4467	ENOG4105MQS	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
B224_4472	ENOG4105DP9	ABC transporter
B224_4475	ENOG4106SMU	thiamine transporter membrane protein
B224_4476	ENOG4107T0D	ABC, transporter
B224_4477	ENOG4108IAB	Phoh family
B224_4482	ENOG4105BZK	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair (By similarity)
B224_4484	ENOG4105D3G	Pseudouridine synthase
B224_4486	ENOG4105BZU	Histidine kinase
B224_4488	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
B224_4490	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
B224_4495	ENOG4108YH1	overproduction of this protein in Escherichia coli inhibits the F plasmid-mediated exclusion of bacteriophage T7
B224_4496	ENOG4108IJ0	Aspartate ammonia-lyase
B224_4498	ENOG4105DS2	Anaerobic c4-dicarboxylate transporter
B224_4499	ENOG4105D9M	gamma-glutamylcysteine synthetase
B224_4503	ENOG4105W39	Membrane
B224_4504	ENOG4105DQ4	alcohol dehydrogenase
B224_4510	ENOG4105DP0	ferredoxin-NADP reductase
B224_4511	ENOG4105K9Q	Binds to the 23S rRNA (By similarity)
B224_4513	ENOG4105VH8	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity)
B224_4514	ENOG4108ZDX	Binds together with S18 to 16S ribosomal RNA (By similarity)
B224_4515	ENOG4105C56	H( )-stimulated, divalent metal cation uptake system (By similarity)
B224_4519	ENOG4107YB6	acetyltransferase, (GNAT) family
B224_4521	ENOG4105C2N	RNA methyltransferase TrmH family group 3
B224_4523	ENOG4105C40	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity)
B224_4525	ENOG4106TD9	Diguanylate cyclase
B224_4527	ENOG4106762	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD) (By similarity)
B224_4529	ENOG4108YZA	Nitrogen regulatory protein pii
B224_4531	ENOG4105C4K	Nad synthetase
B224_4532	ENOG410600T	transposase
B224_4536	ENOG4105F5W	AtP-binding protein
B224_4537	ENOG4105D70	Integrase catalytic subunit
B224_4546	ENOG410600T	transposase
B224_4548	ENOG4105C48	Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) (By similarity)
B224_4549	ENOG41090X3	Peptidyl-prolyl cis-trans isomerase
B224_4550	ENOG4105M02	This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity)
B224_4553	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
B224_4554	ENOG4105DTN	riboflavin biosynthesis protein ribF
B224_4556	ENOG4105CJR	Integral membrane protein (MviN
B224_4559	ENOG4105KQV	Binds directly to 16S ribosomal RNA (By similarity)
B224_4560	ENOG41080HT	Transcriptional regulator, arsr family
B224_4562	ENOG41063Z6	transcriptional regulator, lysR family
B224_4564	ENOG4105DRC	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity)
B224_4565	ENOG4105C0V	Provides the sole de novo source of dTMP for DNA biosynthesis (By similarity)
B224_4566	ENOG4105C3B	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity)
B224_4567	ENOG4108HRM	phosphoenolpyruvate--protein phosphotransferase
B224_4569	ENOG4105EJF	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity)
B224_4572	ENOG4108YY1	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity)
B224_4573	ENOG4105D6X	Specifically methylates guanosine-37 in various tRNAs (By similarity)
B224_4574	ENOG4108ZR6	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity)
B224_4575	ENOG4105K5M	30s ribosomal protein S16
B224_4577	ENOG4105CB9	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
B224_4578	ENOG4106KVJ	cytochrome C assembly protein
B224_4580	ENOG4108JU6	CBS domain protein
B224_4582	ENOG4108EGH	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity)
B224_4584	ENOG4108UV7	flagellar protein motX
B224_4585	ENOG4105C80	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
B224_4586	ENOG4105DMR	ABC, transporter
B224_4587	ENOG4105GBT	ABC transporter
B224_4589	ENOG4106PMH	Extracellular solute-binding protein family 3
B224_4591	ENOG4105E5Z	arginine transporter ATP-binding subunit
B224_4592	ENOG410682Y	Regulates arginine biosynthesis genes (By similarity)
B224_4593	ENOG4105EZR	dyp-type peroxidase family protein
B224_4598	ENOG4107QKW	extracellular solute-binding protein family 1
B224_4599	ENOG4108YZA	Nitrogen regulatory protein pii
B224_4600	ENOG4108YZN	class I peptide chain release factor
B224_4603	ENOG4105D9N	nucleoside
B224_4605	ENOG4105HEI	LysR family (Transcriptional regulator
B224_4611	ENOG4105BZW	Glycerate kinase
B224_4612	ENOG4107QQ0	gntp family
B224_4615	ENOG4108IXP	Carbohydrate diacid transcriptional activator CdaR
B224_4616	ENOG4105XTV	UPF0231 protein
B224_4620	ENOG4105VZ9	UPF0235 protein
B224_4621	ENOG4108VIA	integral membrane protein
B224_4622	ENOG4105II7	pyrroline-5-carboxylate reductase
B224_4623	ENOG4105DFA	alanine racemase domain protein
B224_4624	ENOG4105CZX	twitching motility protein
B224_4626	ENOG4105CZX	twitching motility protein
B224_4628	ENOG4105D1Q	UPF0246 protein
B224_4629	ENOG4105C1J	atp-dependent rna helicase
B224_4631	ENOG4107S47	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC) (By similarity)
B224_4633	ENOG4105CWM	branched-chain amino acid transport system II carrier protein
B224_4637	ENOG4105MYN	Zinc uptake regulation protein
B224_4639	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
B224_4643	ENOG4105K70	DNA-binding protein
B224_4645	ENOG4108ZVW	Anti-RNA polymerase sigma 70 factor
B224_4647	ENOG4105DNJ	May play a role in the repair of endogenous alkylation damage (By similarity)
B224_4652	ENOG4105EAC	phosphoserine phosphatase
B224_4654	ENOG4108NST	exported protein
B224_4658	ENOG4105CZG	Phosphotransfer between the C1 and C5 carbon atoms of pentose (By similarity)
B224_4659	ENOG4105CMW	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis (By similarity)
B224_4661	ENOG4105FCI	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate (By similarity)
B224_4665	ENOG4105D9N	nucleoside
B224_4666	ENOG4105EYA	deoxyribonuclease
B224_4672	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
B224_4674	ENOG4105BZU	Histidine kinase
B224_4679	ENOG4108JJ6	Type I secretion system ATPase
B224_4680	ENOG4105E2K	Glycosyl transferase (Group 1
B224_4686	ENOG4105FBQ	ATPase associated with various cellular activities aaa_5
B224_4700	ENOG4108K5H	permease YjgP YjgQ family protein
B224_4703	ENOG4108M8S	permease YjgP YjgQ family protein
B224_4704	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
B224_4706	ENOG4105MYG	DNA polymerase iii, chi subunit
B224_4708	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
B224_4711	ENOG4106W5V	Membrane
B224_4712	ENOG41061WM	D-Alanyl-D-Alanine
B224_4713	ENOG4105VM8	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding (By similarity)
B224_4714	ENOG4105CFH	Aspartokinase
B224_4716	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
B224_4721	ENOG4105C68	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity)
B224_4722	ENOG4107TH8	cina domain protein
B224_4725	ENOG4105D86	that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity)
B224_4730	ENOG4105R2J	Conserved Protein
B224_4734	ENOG4105DR5	peptidase
B224_4741	ENOG4105NXV	High-affinity zinc uptake system protein
B224_4742	ENOG4105FDK	ABC transporter
B224_4743	ENOG4105FAV	ABC, transporter
B224_4744	ENOG4105ETT	transcriptional Regulator, LysR family
B224_4746	ENOG4108RG0	uracil-dna glycosylase
B224_4748	ENOG41082IR	Excinuclease ABC C subunit domain protein
B224_4751	ENOG41087YS	Phage shock protein A
B224_4752	ENOG4107S7E	1-acyl-sn-glycerol-3-phosphate acyltransferase
B224_4758	ENOG4105N2G	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
B224_4760	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
B224_4774	ENOG4105F2I	Transposase
B224_4777	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
B224_4779	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
B224_4782	ENOG4105IPS	esterase
B224_4783	ENOG41070EG	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes (By similarity)
B224_4784	ENOG4108SX3	cytoplasmic protein
B224_4785	ENOG41087AY	ADP-Ribose pyrophosphatase
B224_4786	ENOG4105DFG	type I secretion outer membrane protein
B224_4788	ENOG4105DW0	Catalyzes the ADP transfer to D-glycero-D-manno-heptose 1-phosphate, yielding ADP-D,D-heptose (By similarity)
B224_4790	ENOG4105D1S	lipid A biosynthesis
B224_4797	ENOG4107RNS	bifunctional 2',3'-cyclic nucleotide 2'-phosphodiesterase 3'-nucleotidase periplasmic
B224_4798	ENOG4108ZUB	Lysine exporter protein (Lyse ygga)
B224_4799	ENOG4105VJY	transcriptional regulator
B224_4801	ENOG4105NNS	Autoinducer synthesis protein
B224_4803	ENOG4105CXD	Specific inhibitor of chromosomal initiation of replication in vitro. Binds the three 13-mers in the origin (oriC) to block initiation of replication (By similarity)
B224_4804	ENOG4108IEC	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction (By similarity)
B224_4807	ENOG4105D70	Integrase catalytic subunit
B224_4808	ENOG4105F5W	AtP-binding protein
B224_4811	ENOG4105CTS	PTS system mannitol-specific
B224_4813	ENOG4107SQ3	mannitol-1-phosphate 5-dehydrogenase
B224_4815	ENOG4105E61	Mannitol repressor protein
B224_4823	ENOG4108UPT	UPF0178 protein
B224_4827	ENOG4105D9N	nucleoside
B224_4831	ENOG410600T	transposase
B224_4832	ENOG4105C1J	atp-dependent rna helicase
B224_4840	ENOG4105EIS	1,4-dihydroxy-2-naphthoate octaprenyltransferase
B224_4841	ENOG4105E4F	Isochorismate synthase
B224_4842	ENOG4105C4A	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC) (By similarity)
B224_4844	ENOG4107J5P	Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC). Is also able to catalyze the hydrolysis of the thioester bond in palmitoyl-CoA in vitro (By similarity)
B224_4846	ENOG4108IPT	Naphthoate synthase
B224_4847	ENOG4105DNI	Converts SHCHC to OSB (By similarity)
B224_4849	ENOG4105CEY	Amp-dependent synthetase and ligase
B224_4851	ENOG4107MM9	BNR Asp-box repeat-containing protein
B224_4852	ENOG4108UB4	uncharacterized protein ygjQ
B224_4855	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
B224_4857	ENOG4107IFA	Lipase (EC 3.1.1.3)
B224_4864	ENOG4108IQK	o-acetylhomoserine
B224_4868	ENOG4108I6A	alcohol dehydrogenase
B224_4871	ENOG4105EMU	Dehydrogenase
B224_4880	ENOG4105E0M	Sulfatase
B224_4881	ENOG4105SYT	Methylenetetrahydrofolate reductase
B224_4887	ENOG4105EIF	outer membrane protein W
B224_4893	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
B224_4894	ENOG41086KC	Transcriptional regulator
B224_4895	ENOG4108UUM	single-stranded DNA-binding protein
B224_4900	ENOG4105E0F	Histidine kinase
B224_4902	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
B224_4909	ENOG4105BZU	Histidine kinase
B224_4910	ENOG4108YZA	Nitrogen regulatory protein pii
B224_4914	ENOG4105KHA	Glyoxalase Bleomycin resistance protein (Dioxygenase
B224_4917	ENOG410600T	transposase
B224_4919	ENOG4105F2I	Transposase
B224_4920	ENOG4107QYX	exodeoxyribonuclease v alpha
B224_4923	ENOG4107QKA	exodeoxyribonuclease V beta
B224_4926	ENOG4105DSY	exodeoxyribonuclease V, gamma
B224_4927	ENOG4108VBZ	doxx family
B224_4929	ENOG4105C2I	pirin domain protein
B224_4931	ENOG4105CWB	LysR family transcriptional Regulator
B224_4941	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
B224_4945	ENOG4105BZU	Histidine kinase
B224_4948	ENOG4105CF7	AraC family transcriptional regulator
B224_4949	ENOG4108RTV	Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol (By similarity)
B224_4951	ENOG4105CH6	catalase
B224_4960	ENOG4105IPI	Membrane
B224_4964	ENOG4108JU9	GAF modulated sigma54 specific transcriptional regulator Fis family
B224_4969	ENOG4108UTZ	Dihydroxyacetone kinase
B224_4970	ENOG4105CMT	Dihydroxyacetone kinase
B224_4972	ENOG4105C7N	Xanthine uracil vitamin C permease
B224_4974	ENOG4105D70	Integrase catalytic subunit
B224_4975	ENOG4105F5W	AtP-binding protein
B224_4979	ENOG4108ZI0	d,d-heptose 1,7-bisphosphate phosphatase
B224_4981	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
B224_4984	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
B224_4985	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
B224_4986	ENOG4105YKK	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions (By similarity)
B224_4990	ENOG4105KME	endoribonuclease L-psp
B224_4991	ENOG4105WWK	YheO domain protein
B224_4994	ENOG4105D27	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
B224_4997	ENOG4108IIJ	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
B224_4998	ENOG4105KBC	Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity)
B224_4999	ENOG4108VZM	50s ribosomal protein L10
B224_5000	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
B224_5002	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
B224_5003	ENOG4105E5V	Participates in transcription elongation, termination and antitermination (By similarity)
B224_5005	ENOG4105PM1	preprotein translocase subunit SecE
B224_5006	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
B224_5008	ENOG4105CS9	pantothenic acid kinase
B224_5009	ENOG4105HJX	Biotin- acetyl-CoA-carboxylase ligase
B224_5010	ENOG4105D4A	Cell wall formation (By similarity)
B224_5013	ENOG4107ZYR	domain protein
B224_5017	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
B224_5018	ENOG4105CUW	cytochrome C-TYPE protein
B224_5020	ENOG4107QY8	reductase
B224_5023	ENOG4105IFJ	Histidine kinase
B224_5025	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
B224_5029	ENOG4105DQ2	Is probably involved in the electron transfer between its heme and the molybdenum cofactor of the reductase catalytic subunit YedY (By similarity)
B224_5032	ENOG4108UQ5	membrane protein YcdZ
B224_5033	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
B224_5037	ENOG4107WP9	Histidine kinase
B224_5040	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
B224_5041	ENOG410642E	Short chain dehydrogenase
B224_5046	ENOG4108VVK	transcriptional Regulator, AsnC
B224_5047	ENOG4105CU9	asparagine synthetase A
B224_5049	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
B224_5050	ENOG4105DBW	Multi-copper polyphenol oxidoreductase laccase
B224_5051	ENOG4105C34	Pseudouridine synthase
B224_5052	ENOG4106SNF	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
B224_5053	ENOG4107QMW	pyridine nucleotide-disulfide oxidoreductase
B224_5054	ENOG4107R6U	sodium dicarboxylate symporter
B224_5055	ENOG4105CEM	UPF0597 protein
B224_5058	ENOG4105C15	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
B224_5059	ENOG4108IIE	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
B224_5062	ENOG4108I6A	alcohol dehydrogenase
B224_5063	ENOG4105CF7	AraC family transcriptional regulator
B224_5065	ENOG4105QNF	Outer membrane lipoprotein
B224_5067	ENOG4105C8Q	Methyl-accepting chemotaxis
B224_5071	ENOG4105DJ4	phosphatidylserine decarboxylase
B224_5073	ENOG4105CXT	aspartate transcarbamylase
B224_5074	ENOG4108R9M	Involved in allosteric regulation of aspartate carbamoyltransferase (By similarity)
B224_5075	ENOG410682Y	Regulates arginine biosynthesis genes (By similarity)
B224_5076	ENOG4105CSX	c4-dicarboxylate anaerobic carrier
B224_5077	ENOG4105DBV	ornithine carbamoyltransferase
B224_5079	ENOG4105C5B	carbamate kinase
B224_5087	ENOG4105C8Q	Methyl-accepting chemotaxis
B224_5089	ENOG4108HWV	)-transporter
B224_5091	ENOG4105C2J	ABC transporter
B224_5095	ENOG4105CNT	hydrolase family 2
B224_5096	ENOG41060NJ	transcriptional regulator
B224_5097	ENOG4105CMR	udp-glucose 4-epimerase
B224_5098	ENOG4105F0Z	galactose-1-phosphate uridylyltransferase
B224_5099	ENOG4105CRD	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P) (By similarity)
B224_5101	ENOG4105ENN	converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose (By similarity)
B224_5102	ENOG4105CPC	Aldo Keto reductase
B224_5103	ENOG4105DWR	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity)
B224_5104	ENOG4108NIX	Factor ChrR
B224_5105	ENOG4105K6V	RNA polymerase
B224_5107	ENOG4105C75	arginyL-tRNA synthetase
B224_5110	ENOG4108R5P	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery (By similarity)
B224_5111	ENOG4105C4N	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis (By similarity)
B224_5116	ENOG4105D0S	secretion protein (HlyD
B224_5117	ENOG4105CJ1	ABC, transporter
B224_5118	ENOG4107QWP	ABC-2 type transporter
B224_5120	ENOG4107QWP	ABC-2 type transporter
B224_5123	ENOG4107QZF	nitrite reductase NADPH large subunit
B224_5125	ENOG4105WZK	nitrite reductase NADPH small subunit
B224_5126	ENOG4107V9H	nitrite transporter
B224_5127	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
B224_5128	ENOG4105CJW	magnesium transporter
B224_5130	ENOG4108YYX	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. Modulates RNA-binding and helicase activities of the degradosome (By similarity)
B224_5131	ENOG4105EX9	Membrane
B224_5133	ENOG4105CNG	UPF0061 protein
B224_5135	ENOG4105N7H	Cytochrome
B224_5138	ENOG4105C9U	ATP-dependent DNA helicase RecQ
B224_5141	ENOG4108VUY	thioesterase Superfamily protein
B224_5148	ENOG4108RPX	mosc domain containing protein
B224_5150	ENOG4105D38	putrescine abc transporter
B224_5152	ENOG4105F38	ABC transporter, permease
B224_5155	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
B224_5156	ENOG4108HM4	ABC transporter
B224_5160	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
B224_5162	ENOG4105CFQ	glutamine synthetase
B224_5163	ENOG4108V7X	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
B224_5169	ENOG4108RH0	Crea protein
B224_5170	ENOG4105C5I	Dehydrogenase
B224_5172	ENOG4105R8A	Heat shock protein
B224_5175	ENOG4107R28	alpha amylase, catalytic region
B224_5182	ENOG4107R9T	Catalyzes the formation of 5-methyl-uridine at position 54 (m5U54) in all tRNAs (By similarity)
B224_5183	ENOG4107EXC	regulatoR
B224_5185	ENOG4105JJR	Histidine kinase
B224_5188	ENOG4105C6K	Malic enzyme
B224_5189	ENOG4105CGD	Nad-dependent epimerase dehydratase
B224_5190	ENOG4105VFB	Binds the 23S rRNA (By similarity)
B224_5192	ENOG4105C25	Primosomal protein n'
B224_5195	ENOG4105UYK	outer membrane protein a
B224_5196	ENOG4105F2I	Transposase
B224_5200	ENOG410600T	transposase
B224_5202	ENOG4105C7B	Threonine dehydratase
B224_5204	ENOG4105C01	Dihydroxy-acid dehydratase
B224_5206	ENOG4105CM2	brancheD-chain amino acid aminotransferase
B224_5207	ENOG4105P3Y	Acetolactate synthase 2 regulatory subunit
B224_5210	ENOG4105C0P	Mg chelatase subunit ChlI
B224_5211	ENOG4106HNH	Acyl-transferase
B224_5212	ENOG4106HNH	Acyl-transferase
B224_5217	ENOG4108RWI	nicotinamidase
B224_5218	ENOG4107RH7	Nicotinate phosphoribosyltransferase
B224_5219	ENOG4105EHI	Phosphonate ABC transporter, periplasmic
B224_5220	ENOG4108VA1	ABC transporter
B224_5221	ENOG4105S7S	phosphonate abc transporter
B224_5223	ENOG4108Z33	Thiol disulfide Interchange Protein
B224_5224	ENOG4105E27	serine threonine protein kinase
B224_5229	ENOG4105PC1	Conserved Protein
B224_5234	ENOG4107QP2	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
B224_5235	ENOG4105ED0	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates (By similarity)
B224_5236	ENOG4105DSJ	YicC domain protein
B224_5239	ENOG4105D8A	3-Deoxy-D-manno-octulosonic-acid transferase
B224_5241	ENOG4105XA0	heptosyltransferase ii
B224_5242	ENOG4106WTF	Glycosyl transferase, family 2
B224_5244	ENOG4105M5K	heptosyltransferase
B224_5246	ENOG4108ZEF	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity)
B224_5247	ENOG4108MJ5	VirK protein
B224_5249	ENOG4105ERD	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity)
B224_5251	ENOG4105W0E	50S ribosomal protein L33
B224_5252	ENOG4105W5Q	DNA repair protein (RadC
B224_5254	ENOG4105CJS	Phosphopantothenoylcysteine decarboxylase
B224_5255	ENOG4108Z1K	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA (By similarity)
B224_5257	ENOG4105EC0	Required for nucleoid occlusion (NO) phenomenon, which prevents Z-ring formation and cell division over the nucleoid. Acts as a DNA-associated cell division inhibitor that binds simultaneously chromosomal DNA and FtsZ, and disrupts the assembly of FtsZ polymers. SlmA-DNA-binding sequences (SBS) are dispersed on non-Ter regions of the chromosome, preventing FtsZ polymerization at these regions (By similarity)
B224_5258	ENOG4105D64	Mechanosensitive ion channel
B224_5260	ENOG4107QP8	phosphohexose isomerase
B224_5262	ENOG4105C6M	Alpha-keto-beta-hydroxylacyl reductoisomerase
B224_5264	ENOG4105EMY	transcriptional regulator
B224_5266	ENOG4105CD5	CoA-binding domain protein
B224_5269	ENOG4105F03	Provides the (R)-glutamate required for cell wall biosynthesis (By similarity)
B224_5271	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
B224_5272	ENOG4108UM6	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity)
B224_5273	ENOG4105CY8	phosphoribosylaminoimidazole carboxylase atpase subunit
B224_5276	ENOG4105FCD	Major Facilitator
B224_5277	ENOG4105DY9	regulatoR
B224_5279	ENOG4108HRK	Histidine kinase
B224_5283	ENOG4105EU0	Major facilitator Superfamily
B224_5284	ENOG4105CBX	hi0933 family
B224_5286	ENOG41090A1	ferritin
B224_5287	ENOG4105BZU	Histidine kinase
B224_5288	ENOG4105RKW	reductase (By
B224_5289	ENOG4108M6U	Universal stress protein A
B224_5295	ENOG4105EMK	carboxylate amino acid amine transporter
B224_5297	ENOG4108W7E	Catalyzes the ATP-dependent phosphorylation of the 3- deoxy-D-manno-octulosonic acid (Kdo) residue in Kdo-lipid IV(A) at the 4-OH position (By similarity)
B224_5298	ENOG4105DKP	glycosyl transferase, family 9
B224_5301	ENOG4105VFG	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity)
B224_5302	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
B224_5305	ENOG4105FE8	tRNA (Guanosine-2'-O-)-methyltransferase
B224_5306	ENOG4108EUD	Lysophospholipase
B224_5307	ENOG4105DQF	Hydrolase
B224_5309	ENOG4105Y7M	Transcriptional regulator, TetR family
B224_5310	ENOG410624X	efflux transporter, rnd family, mfp subunit
B224_5312	ENOG4105BZS	acriflavin resistance protein
B224_5315	ENOG4105BZU	Histidine kinase
B224_5316	ENOG4105DC8	reductase
B224_5319	ENOG4105CB2	alcohol dehydrogenase
B224_5321	ENOG4105KVH	Transcriptional regulator
B224_5323	ENOG4105D9K	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity)
B224_5324	ENOG4105C8X	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity)
B224_5329	ENOG4105C08	Histidine kinase
B224_5331	ENOG4105EEX	Two component transcriptional regulator (Winged helix family
B224_5333	ENOG4105C2C	drug resistance transporter, Bcr CflA
B224_5336	ENOG4105JKW	Valine--pyruvate aminotransferase
B224_5338	ENOG4108ZNX	Heat shock protein
B224_5340	ENOG4108ZNX	Heat shock protein
B224_5342	ENOG4105IGJ	Zn-dependent Hydrolase of the beta-lactamase fold protein
B224_5343	ENOG4105ECQ	AraC Family Transcriptional Regulator
B224_5344	ENOG4105D29	Helix-turn-helix type 11 domain protein
B224_5347	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
B224_5348	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
B224_5349	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
B224_5351	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
B224_5352	ENOG4105EAB	amino acid AbC transporter
B224_5353	ENOG4105E5Q	amino acid AbC transporter
B224_5354	ENOG4105CDA	abc transporter atp-binding protein
B224_5355	ENOG4105VG0	50S ribosomal protein l34
B224_5356	ENOG4105NVJ	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme (By similarity)
B224_5357	ENOG4105DHW	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
B224_5358	ENOG4105C1H	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity)
B224_5359	ENOG4105S6R	Iron-hydroxamate transporter permease subunit
B224_5360	ENOG4105J76	Periplasmic binding protein
B224_5361	ENOG4105E0A	ABC, transporter
B224_5363	ENOG4105IBP	Cyclic peptide transporter
B224_5365	ENOG4105E0K	tonB-dependent siderophore receptor
B224_5367	ENOG4105QTB	Flavodoxin
B224_5370	ENOG4107RE5	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity)
B224_5371	ENOG4105D28	Specifically methylates the N7 position of a guanine in 16S rRNA (By similarity)
B224_5373	ENOG4107QJE	Chromosome Partitioning Protein
B224_5374	ENOG4105FA0	parb-like partition protein
B224_5375	ENOG4105EE4	it plays a direct role in the translocation of protons across the membrane (By similarity)
B224_5376	ENOG4105KY6	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
B224_5377	ENOG4107Z6K	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
B224_5379	ENOG4107S15	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
B224_5380	ENOG4105CDG	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity)
B224_5382	ENOG4105J80	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity)
B224_5384	ENOG4105C4J	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity)
B224_5385	ENOG4105KNM	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
B224_5387	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
B224_5388	ENOG4105CT7	inner membrane cred family protein
B224_5392	ENOG4105EB3	Histidine kinase
B224_5393	ENOG4105E3W	Two component transcriptional regulator (Winged helix family
B224_5395	ENOG410804X	Transcriptional regulator
B224_5397	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
B224_5399	ENOG4105VJY	transcriptional regulator
B224_5405	ENOG4109015	Biopolymer transport protein exbD tolR
B224_5406	ENOG410822N	TonB family
B224_5410	ENOG4105CQ4	Transcriptional regulator
B224_5413	ENOG4105CNT	hydrolase family 2
B224_5414	ENOG4105FK9	beta-D-galactosidase beta subunit
B224_5415	ENOG4105E5D	amino acid
B224_5417	ENOG4108Y51	tRNA-binding protein
B224_5418	ENOG4105E5D	amino acid
B224_5419	ENOG4105DHU	Bile acid
B224_5422	ENOG4105E46	N-alpha,N-alpha,N-alpha-trimethyl-L-histidine metabolic process
B224_5426	ENOG4105C4W	S-formylglutathione hydrolase
B224_5429	ENOG4105CC0	LysR family Transcriptional regulator
B224_5435	ENOG4105UIB	(ABC) transporter
B224_5438	ENOG4108JQ9	ABC transporter
B224_5440	ENOG4105DIH	basic membrane
B224_5443	ENOG4105C4R	Atp-dependent dna helicase
B224_5449	ENOG4108YH8	Covalently attaches a chromophore to Cys residue(s) of phycobiliproteins (By similarity)
B224_5451	ENOG4105CUC	YeeE YedE family protein
B224_5454	ENOG4105ECQ	AraC Family Transcriptional Regulator
B224_5456	ENOG4105FR1	rard protein
B224_5460	ENOG4105C26	Dehydrogenase
B224_5463	ENOG4108JCI	Transcriptional regulator
B224_5464	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
B224_5467	ENOG4105C26	Dehydrogenase
B224_5468	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
B224_5469	ENOG4107R11	Transcriptional regulator
B224_5470	ENOG4108TFM	Kinase, PfkB family
B224_5475	ENOG4105CGY	Dna recombination protein
B224_5477	ENOG4105D37	Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA (By similarity)
B224_5478	ENOG4105C1A	potassium transporter peripheral membrane
B224_5479	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
B224_5480	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
B224_5482	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
B224_5485	ENOG4105C79	DNA protecting protein DprA
B224_5486	ENOG4108RPN	Protein smg homolog
B224_5487	ENOG4108WI1	Dna topoisomerase
B224_5488	ENOG4105EK0	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
B224_5489	ENOG4105DBS	Key enzyme in heme biosynthesis. Catalyzes the oxidative decarboxylation of propionic acid side chains of rings A and B of coproporphyrinogen III (By similarity)
B224_5490	ENOG4105E2X	shikimate dehydrogenase
B224_5491	ENOG4105WHM	Necessary for normal cell division and for the maintenance of normal septation (By similarity)
B224_5492	ENOG4106RE7	Cytochrome
B224_5493	ENOG4105ZR3	A GTPase-activating protein (GAP) that modifies Der EngA GTPase function. May play a role in ribosome biogenesis (By similarity)
B224_5495	ENOG4105XCT	Protein of unknown function (DUF2489)
B224_5496	ENOG4105D4P	Coproporphyrinogen iii oxidase
B224_5499	ENOG410600T	transposase
B224_5501	ENOG4105EKD	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism (By similarity)
B224_5503	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
B224_5504	ENOG4105CUX	Signal transduction histidine kinase
B224_5508	ENOG4105C5F	glutamine synthetase
B224_5510	ENOG4107S2Z	UPF0761 membrane protein
B224_5512	ENOG4107S2Z	UPF0761 membrane protein
B224_5514	ENOG4108YYA	Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine (By similarity)
B224_5518	ENOG4105SUU	thioesterase domain
B224_5522	ENOG4105CB5	ATP-dependent DNA helicase recG
B224_5523	ENOG4105JIM	Phosphatidylserine synthase
B224_5524	ENOG4105C6Z	Gluconate
B224_5525	ENOG4108Z67	carbohydrate kinase, thermoresistant glucokinase family
B224_5526	ENOG4105C01	Dihydroxy-acid dehydratase
B224_5527	ENOG4108UHU	Aldolase
B224_5529	ENOG4105DIQ	Transcriptional regulator
B224_5533	ENOG41063SB	peptidase
B224_5534	ENOG4107YZP	Rhodanese domain protein
B224_5535	ENOG4105CJI	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
B224_5536	ENOG4105IX2	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA (By similarity)
B224_5537	ENOG4105CSF	NADPH-dependent glycerol-3-phosphate dehydrogenase
B224_5538	ENOG4107RUK	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins (By similarity)
B224_5540	ENOG4105MJ2	Competence protein
B224_5541	ENOG4105D3C	The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters (By similarity)
B224_5545	ENOG4105BZM	domain protein
B224_5547	ENOG4108RRZ	Transcription elongation factor GreB
B224_5548	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
B224_5549	ENOG4105E0F	Histidine kinase
B224_5551	ENOG4108Z10	Involved in the binding of tRNA to the ribosomes (By similarity)
B224_5552	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
B224_5553	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
B224_5554	ENOG41080KG	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
B224_5555	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
B224_5556	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
B224_5557	ENOG4105KAP	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity)
B224_5558	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
B224_5560	ENOG4108R70	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity)
B224_5561	ENOG41083MP	50s ribosomal protein l29
B224_5562	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
B224_5563	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
B224_5564	ENOG4105KAR	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity)
B224_5565	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
B224_5566	ENOG4105VBI	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
B224_5567	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
B224_5568	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
B224_5569	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
B224_5571	ENOG4105CGG	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity)
B224_5573	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
B224_5574	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
B224_5576	ENOG4105CTF	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
B224_5579	ENOG4105F5W	AtP-binding protein
B224_5580	ENOG4105D70	Integrase catalytic subunit
B224_5581	ENOG4105DQW	permease for cytosine purines, uracil, thiamine, allantoin
B224_5582	ENOG4105DZC	cytosine deaminase
B224_5584	ENOG4105WMR	Protein CrcB homolog
B224_5585	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
B224_5586	ENOG4105JC1	sterol-binding domain protein
B224_5588	ENOG4105CNK	Required, probably indirectly, for the hydroxylation of 2-octaprenylphenol to 2-octaprenyl-6-hydroxy-phenol, the fourth step in ubiquinone biosynthesis (By similarity)
B224_5589	ENOG4105WKS	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity)
B224_5590	ENOG4105X8U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation (By similarity)
B224_5591	ENOG4105DCX	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity)
B224_5593	ENOG4105F8V	Hydrolase, tatD family
B224_5595	ENOG4105D52	delta-aminolevulinic acid dehydratase
B224_5596	ENOG4105DGW	oligopeptidase A
B224_5599	ENOG4105BZU	Histidine kinase
B224_5600	ENOG4105FFN	Specifically methylates the guanosine in position 1516 of 16S rRNA (By similarity)
B224_5604	ENOG4105C9X	ppx gppa phosphatase
B224_5605	ENOG4105C1J	atp-dependent rna helicase
B224_5606	ENOG4105K63	Thioredoxin
B224_5607	ENOG4105C4P	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity)
B224_5609	ENOG4105D3H	Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol (By similarity)
B224_5611	ENOG4107QK7	reductase
B224_5613	ENOG4105W0Z	cytoplasmic protein
B224_5618	ENOG4105M78	Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide (By similarity)
B224_5623	ENOG4108IV0	ABC, transporter
B224_5624	ENOG4105C0Z	ABC transporter
B224_5626	ENOG4105CF8	branched-chain amino acid ABC transporter, permease
B224_5627	ENOG4105C32	Amino acid ABC transporter (Permease)
B224_5628	ENOG4105CP9	extracellular ligand-binding receptor
B224_5629	ENOG4105ETE	Transcriptional regulator (LacI family
B224_5631	ENOG4108JUA	Transcriptional regulator
B224_5633	ENOG4105CNW	domain protein
B224_5635	ENOG4108EQM	faD-dependent pyridine nucleotide-disulfide oxidoreductase
B224_5639	ENOG4105HEE	Binding Domain protein
B224_5641	ENOG4105C0F	tryptophanase EC 4.1.99.1
B224_5643	ENOG410600T	transposase
B224_5644	ENOG4105CIC	tryptophan-specific transport protein
B224_5645	ENOG4105CIC	tryptophan-specific transport protein
B224_5650	ENOG4105C38	Glycyl-tRNA synthetase beta subunit
B224_5652	ENOG4108HMW	glycyl-tRNA synthetase, alpha subunit
B224_5653	ENOG4108R3E	Dna-3-methyladenine glycosylase i
B224_5660	ENOG4108ZG0	Ompa motb domain protein
B224_5661	ENOG4105M4H	endoribonuclease L-psp
B224_5663	ENOG41082K8	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Interacts with IscS and stimulates its activity. Then, accepts a sulfur from IscS and transfers it in turn to TusD (By similarity)
B224_5666	ENOG4105T29	extracellular solute-binding protein
B224_5668	ENOG4105E0F	Histidine kinase
B224_5670	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
B224_5671	ENOG4105CHU	acetyl-coa acetyltransferase
B224_5673	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
B224_5674	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
B224_5676	ENOG4105D9Y	Splits dipeptides with a prolyl residue in the C- terminal position (By similarity)
B224_5677	ENOG4108ZK7	protein family UPF0029, Impact, N-terminal protein
B224_5679	ENOG4105D37	Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA (By similarity)
B224_5680	ENOG4108RR8	protoporphyrinogen oxidase
B224_5682	ENOG4105CUZ	uba thif-type nad fad binding protein
B224_5685	ENOG4105P9C	Participates in cysteine desulfuration mediated by SufS. Cysteine desulfuration mobilizes sulfur from L-cysteine to yield L-alanine and constitutes an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules. Functions as a sulfur acceptor for SufS, by mediating the direct transfer of the sulfur atom from the S-sulfanylcysteine of SufS, an intermediate product of cysteine desulfuration process (By similarity)
B224_5686	ENOG4105C9B	Cysteine desulfurase
B224_5687	ENOG4105C4R	Atp-dependent dna helicase
B224_5689	ENOG4105BZU	Histidine kinase
B224_5691	ENOG4105CPQ	Dehydrogenase
B224_5692	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
B224_5693	ENOG41062JF	Transcriptional regulator
B224_5694	ENOG4105CUI	Catalyzes the interconversion between ADP-D-glycero- beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose (By similarity)
B224_5696	ENOG4105E2K	Glycosyl transferase (Group 1
B224_5698	ENOG4105PF3	O-Antigen polymerase
B224_5703	ENOG410600T	transposase
B224_5706	ENOG4105D3Z	quinone oxidoreductase, yhdh yhfp family
B224_5711	ENOG4105X6C	Flagellar basal body-associated protein FliL
B224_5712	ENOG4105VEI	Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4- hydroxybenzoate (4HB) for the ubiquinone pathway (By similarity)
B224_5713	ENOG4105C4G	Synthesis of 3-octaprenyl-4-hydroxybenzoate (By similarity)
B224_5715	ENOG4105E55	glycerol-3-phosphate acyltransferase
B224_5716	ENOG4105DS7	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity)
B224_5721	ENOG4107R73	Mate efflux family protein
B224_5722	ENOG4108UIQ	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity)
B224_5723	ENOG4105E0F	Histidine kinase
B224_5724	ENOG4105E3W	Two component transcriptional regulator (Winged helix family
B224_5727	ENOG4105D7W	serine acetyltransferase
B224_5729	ENOG41065UX	Non-essential, abundant cell division factor that is required for proper Z-ring formation. It is recruited early to the divisome by direct interaction with FtsZ, stimulating Z-ring assembly and thereby promoting cell division earlier in the cell cycle. Its recruitment to the Z-ring requires functional FtsA or ZipA (By similarity)
B224_5730	ENOG4108556	Isoprenoid biosynthesis protein with amidotransferase-like domain
B224_5732	ENOG4105C2M	dna polymerase I
B224_5734	ENOG4108Z0R	Transferase
B224_5735	ENOG4107QWG	2-Nitropropane dioxygenase
B224_5742	ENOG4107V4F	S-adenosyl-l-methionine hydroxide adenosyltransferase
B224_5744	ENOG4105FSR	swimming returnes to normal when residues 206-207 are both mutated to Ala. Overexpression also leads to a reduction in flagellar abundance and a 20-fold increase in c-di- GMP levels in vivo. Required for aminoglycoside-mediated induction of biofilm formation, it also plays a lesser role in biofilm production in response to other classes of translation inhibitors. The c-di-GMP produced by this enzyme up-regulates poly-GlcNAc production as well as the biofilm synthesis protein PgaD, although c-di-GMP is probably not the main inducing principle. Cyclic-di- GMP is a second messenger which controls cell surface-associated traits in bacteria
B224_5745	ENOG4105C1J	atp-dependent rna helicase
B224_5750	ENOG4107YH7	Beta-lactamase (EC 3.5.2.6)
B224_5762	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
B224_5764	ENOG4105DWY	Agmatine deiminase
B224_5771	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
B224_5773	ENOG4108MJ3	acetyltransferase
B224_5775	ENOG4105C8A	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP (By similarity)
B224_5777	ENOG4105BZU	Histidine kinase
B224_5778	ENOG4105BZU	Histidine kinase
B224_5781	ENOG4105EV2	VWA domain protein interacting with AAA ATPase
B224_5785	ENOG41080E2	ribosomal-protein-alanine acetyltransferase
B224_5788	ENOG4108IQE	Amp-dependent synthetase and ligase
B224_5794	ENOG4107SQD	Transcriptional regulator, GntR family
B224_5798	ENOG4105C8J	)-transporter
B224_5799	ENOG4105C8J	)-transporter
B224_5802	ENOG410667J	hydrolase
B224_5808	ENOG4105EW9	transcriptional regulator AsnC family
B224_5813	ENOG4105K56	Transcriptional regulator
B224_5814	ENOG4105CJH	Alcohol dehydrogenase zinc-binding domain protein
B224_5821	ENOG4105E0X	reductase
B224_5827	ENOG4105C9C	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity)
B224_5829	ENOG4107RTM	4-alpha-glucanotransferase (EC 2.4.1.25)
B224_5830	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
B224_5831	ENOG4105DSB	aldose 1-epimerase
B224_5833	ENOG4105D0I	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate (By similarity)
B224_5835	ENOG4105UFD	tol-pal system protein YbgF
B224_5836	ENOG4105KCK	Peptidoglycan-associated lipoprotein
B224_5837	ENOG4107R6Y	Involved in the TonB-independent uptake of proteins (By similarity)
B224_5839	ENOG4105M8F	Biopolymer transport protein exbD tolR
B224_5840	ENOG4105E02	MotA TolQ exbB proton channel
B224_5842	ENOG4107YD3	Thioesterase
B224_5843	ENOG4105KJB	cyd operon protein YbgE
B224_5845	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
B224_5847	ENOG4105C4M	(Ubiquinol oxidase) subunit I
B224_5849	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
B224_5851	ENOG4105KA4	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity)
B224_5852	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
B224_5854	ENOG4108RZ4	Short-chain dehydrogenase reductase Sdr
B224_5858	ENOG4105E39	Enoyl-CoA hydratase
B224_5859	ENOG4106WH9	Protein of unknown function (DUF2753)
B224_5861	ENOG4107QSI	ABC, transporter
B224_5864	ENOG4107RHT	methyl-accepting chemotaxis sensory transducer with Pas Pac sensor
B224_5866	ENOG4108QYW	Bacterial hemolysins are exotoxins that attack blood cell membranes and cause cell rupture. Beta-hemolysin is a phospholipase C with specific activity toward sphingomyelins. Has a high specificity for sphingomyelin, hydrolyzes lysophosphatidylcholine at a much lower rate, but has no activity towards phosphatidylcholine, phosphatidylethanolamine, or phosphatidylserine (By similarity)
B224_5871	ENOG4105C1J	atp-dependent rna helicase
B224_5872	ENOG4108V1J	Has antioxidant activity. Could remove peroxides or H(2)O(2) (By similarity)
B224_5884	ENOG4105EJG	cellulose synthase
B224_5885	ENOG4105K2Z	endo-1,4-d-glucanase (EC 3.2.1.4)
B224_5887	ENOG4107EEX	Cellulose synthase regulator protein
B224_5891	ENOG4107QZ7	Cellulose synthase catalytic subunit
B224_5895	ENOG4105D1V	cellulose synthase operon protein YhjU
B224_5900	ENOG4105CGF	Aromatic amino acid aminotransferase
B224_5904	ENOG41076CZ	activating enzyme
B224_5906	ENOG4105G0K	glycine radical enzyme YjjI family
B224_5916	ENOG4105C8Q	Methyl-accepting chemotaxis
B224_5919	ENOG4108M1A	Chitin-binding protein
B224_5923	ENOG4107R11	Transcriptional regulator
B224_5924	ENOG4108IJ6	ABC transporter
B224_5926	ENOG4105ECW	sulfate abc transporter
B224_5927	ENOG4108I5D	sulfate abc transporter
B224_5929	ENOG4105DE7	Sulfate ABC transporter periplasmic sulfate-binding protein
B224_5932	ENOG4108JCI	Transcriptional regulator
B224_5933	ENOG4105DKK	Benzoate
B224_5935	ENOG4108YXU	transcriptional regulator AsnC family
B224_5938	ENOG4105CVG	Homoserine O-transsuccinylase
B224_5942	ENOG4108I62	cina-like protein
B224_5943	ENOG4107K5X	Membrane-bound metal-dependent hydrolase
B224_5945	ENOG410667J	hydrolase
B224_5946	ENOG4108Z86	Glutamine amidotransferase
B224_5949	ENOG4105DFC	had-superfamily hydrolase, subfamily ia, variant
B224_5951	ENOG4108IYS	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
B224_5953	ENOG4105E4Z	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan (By similarity)
B224_5955	ENOG4105CU5	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity)
B224_5957	ENOG4105XQ6	frataxin-like protein
B224_5958	ENOG4106CJB	Phospholipase Carboxylesterase
B224_5961	ENOG4107T0K	Adenylate cyclase
B224_5962	ENOG4105D6W	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity)
B224_5964	ENOG41076E6	Uroporphyrinogen-III Synthase
B224_5966	ENOG4105ECF	c-methyltransferase
B224_5968	ENOG410601J	HemY protein
B224_5971	ENOG4105KRS	Proteinase inhibitor
B224_5972	ENOG4105CBT	Fructose-1,6-bisphosphatase
B224_5973	ENOG4105FCK	Membrane
B224_5975	ENOG4108Z7F	N-acetyltransferase
B224_5983	ENOG4105KVH	Transcriptional regulator
B224_5984	ENOG4105N0V	mono-oxygenase ydhR
B224_5986	ENOG4108TPP	exopolysaccharide synthesis
B224_5988	ENOG4105BZU	Histidine kinase
B224_5990	ENOG4108WEF	Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1B (PBP1b) (By similarity)
B224_5996	ENOG4105F2I	Transposase
B224_5997	ENOG4105F2I	Transposase
B224_6001	ENOG4105D41	biosynthesis protein thiH
B224_6002	ENOG4105CA8	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity)
B224_6005	ENOG4105D06	uba thif-type nad fad binding protein
B224_6006	ENOG4108UV6	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity)
B224_6007	ENOG4105CBF	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction (By similarity)
B224_6011	ENOG4108MR7	Arylsulfotransferase
B224_6012	ENOG410600T	transposase
B224_6016	ENOG4105ETX	regulatoR
B224_6019	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
B224_6020	ENOG4105C3R	Methionine synthase
B224_6022	ENOG4105EEQ	Na H antiporter
B224_6027	ENOG4105F2I	Transposase
B224_6028	ENOG410600T	transposase
B224_6030	ENOG410600T	transposase
B224_6032	ENOG4105F2I	Transposase
B224_6033	ENOG4105F5W	AtP-binding protein
B224_6039	ENOG4105CGZ	zinc metallopeptidase
B224_6041	ENOG4105CGZ	zinc metallopeptidase
B224_6043	ENOG4105CSH	Transporter
B224_6049	ENOG4105D1U	peptidase U62 modulator of DNA gyrase
B224_6053	ENOG4105QD6	exported protein
B224_6055	ENOG4105C03	ribonuclease
B224_6056	ENOG4108Z03	MAF-like protein
B224_6057	ENOG4105VQ7	Rod shape-determining protein MreD
B224_6058	ENOG4105N3I	Involved in formation and maintenance of cell shape (By similarity)
B224_6059	ENOG4105DFF	Rod shape-determining protein mreb
B224_6061	ENOG410600T	transposase
B224_6074	ENOG41062P1	Diguanylate cyclase phosphodiesterase
B224_6075	ENOG4105F2I	Transposase
B224_6077	ENOG4107XTP	(EAL) domain protein
B224_6078	ENOG4105EWV	Sodium calcium exchanger membrane region
B224_6080	ENOG4105C84	Histidine ammonia-lyase
B224_6082	ENOG4105CGP	Urocanate hydratase
B224_6084	ENOG41088SP	formiminoglutamate hydrolase
B224_6086	ENOG4105CI2	imidazolone-5-propionate hydrolase
B224_6088	ENOG4105CZE	histidine utilization repressor
B224_6089	ENOG41077A9	carbonic anhydrase
B224_6090	ENOG4105DEK	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
B224_6091	ENOG4105CRP	Part of the ABC transporter FtsEX involved in
B224_6092	ENOG4105CAK	Cell division ATP-binding protein ftsE
B224_6094	ENOG4105CCP	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
B224_p00028	ENOG4108UUM	single-stranded DNA-binding protein