locus-tag	class	description
AHP1_1171	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AHP1_1181	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AHP1_1351	COG2255	four-way junction helicase activity
AHP1_1381	COG0417	DNA replication proofreading
AHP1_1451	COG0756	dUTP diphosphatase activity
AHP1_1581	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
AHP1_161	COG1435	thymidine kinase activity
AHP1_1831	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
AHP1_1891	COG0617	tRNA 3'-terminal CCA addition
AHP1_631	COG0602	queuosine metabolic process
AHP1_651	COG0302	gtp cyclohydrolase
AHP1_741	COG0820	rRNA (adenine-C2-)-methyltransferase activity