locus-tag	class	description
vBAcePPAc_0009	COG0328	RNA-DNA hybrid ribonuclease activity
vBAcePPAc_0024	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
vBAcePPAc_0055	COG0338	D12 class N6 adenine-specific DNA methyltransferase
vBAcePPAc_0072	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
vBAcePPAc_0082	COG3172	ATPase kinase involved in NAD metabolism
vBAcePPAc_0099	COG0756	dUTP diphosphatase activity
vBAcePPAc_0130	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
vBAcePPAc_0131	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
vBAcePPAc_0135	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
vBAcePPAc_0142	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
vBAcePPAc_0142	COG1328	CTP reductase activity
vBAcePPAc_0142	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
vBAcePPAc_0142	COG1328	CTP reductase activity
vBAcePPAc_0143	COG0602	queuosine metabolic process
vBAcePPAc_0148	COG3179	chitinase
vBAcePPAc_0151	COG1702	phosphate starvation-inducible protein PhoH
vBAcePPAc_0158	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery