locus-tag	class	description
KYK33_00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
KYK33_00010	COG0592	DNA-directed DNA polymerase activity
KYK33_00015	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
KYK33_00025	COG2207	Transcriptional regulator
KYK33_00030	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
KYK33_00035	COG0071	Belongs to the small heat shock protein (HSP20) family
KYK33_00040	COG0071	Belongs to the small heat shock protein (HSP20) family
KYK33_00045	COG3977	Valine--pyruvate aminotransferase
KYK33_00060	COG0745	RESPONSE REGULATOR receiver
KYK33_00065	COG2205	protein histidine kinase activity
KYK33_00085	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
KYK33_00090	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KYK33_00090	COG4191	Histidine kinase
KYK33_00095	COG0339	signal peptide processing
KYK33_00105	COG0742	ribosomal rna small subunit methyltransferase
KYK33_00115	COG0248	Ppx GppA phosphatase
KYK33_00120	COG0513	Belongs to the DEAD box helicase family
KYK33_00125	COG3118	belongs to the thioredoxin family
KYK33_00140	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
KYK33_00150	COG2960	long-chain fatty acid transporting porin activity
KYK33_00165	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KYK33_00205	COG1609	Transcriptional regulator
KYK33_00210	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
KYK33_00215	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KYK33_00280	COG0561	phosphatase activity
KYK33_00285	COG2267	carboxylic ester hydrolase activity
KYK33_00290	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KYK33_00295	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
KYK33_00300	COG1758	RNA polymerase activity
KYK33_00310	COG0859	PFAM glycosyl transferase family 9
KYK33_00315	COG3642	lipopolysaccharide core region biosynthetic process
KYK33_00355	COG0589	response to stress
KYK33_00360	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
KYK33_00365	COG3706	GGDEF domain
KYK33_00370	COG1528	Iron-storage protein
KYK33_00375	COG2081	HI0933 family
KYK33_00380	COG1280	lysine exporter protein (LysE YggA)
KYK33_00390	COG3275	phosphorelay sensor kinase activity
KYK33_00395	COG3279	Response regulator of the LytR AlgR family
KYK33_00400	COG2223	nitrite transmembrane transporter activity
KYK33_00405	COG4206	TonB-dependent receptor
KYK33_00410	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
KYK33_00460	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
KYK33_00465	COG0166	Belongs to the GPI family
KYK33_00480	COG0789	Transcriptional regulator
KYK33_00485	COG2203	Gaf domain
KYK33_00485	COG3706	GGDEF domain
KYK33_00485	COG4251	negative regulation of phosphorylation
KYK33_00485	COG5001	Diguanylate cyclase
KYK33_00490	COG3084	Protein conserved in bacteria
KYK33_00500	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
KYK33_00505	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
KYK33_00510	COG3639	organic phosphonate transmembrane transporter activity
KYK33_00515	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
KYK33_00520	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
KYK33_00530	COG1335	isochorismatase
KYK33_00540	COG1683	Conserved Protein
KYK33_00545	COG0204	Acyl-transferase
KYK33_00550	COG0204	Acyl-transferase
KYK33_00555	COG0606	chelatase, subunit chli
KYK33_00565	COG3978	acetolactate synthase activity
KYK33_00575	COG0129	dihydroxy-acid dehydratase activity
KYK33_00615	COG1028	Short-chain dehydrogenase reductase Sdr
KYK33_00640	COG0583	DNA-binding transcription factor activity
KYK33_00645	COG1079	Belongs to the binding-protein-dependent transport system permease family
KYK33_00650	COG4603	Belongs to the binding-protein-dependent transport system permease family
KYK33_00655	COG3845	ABC transporter
KYK33_00660	COG1744	ABC transporter substrate-binding protein PnrA-like
KYK33_00665	COG0210	DNA helicase
KYK33_00705	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KYK33_00710	COG1280	lysine exporter protein (LysE YggA)
KYK33_00730	COG4932	domain protein
KYK33_00730	COG5492	domain, Protein
KYK33_00735	COG1012	belongs to the aldehyde dehydrogenase family
KYK33_00740	COG1396	sequence-specific DNA binding
KYK33_00745	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
KYK33_00755	COG0519	Catalyzes the synthesis of GMP from XMP
KYK33_00755	COG0518	GMP synthase (glutamine-hydrolyzing) activity
KYK33_00760	COG0686	Belongs to the AlaDH PNT family
KYK33_00765	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KYK33_00785	COG1322	Protein conserved in bacteria
KYK33_00790	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
KYK33_00795	COG0569	domain protein
KYK33_00800	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
KYK33_00800	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
KYK33_00805	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
KYK33_00810	COG0242	peptide deformylase activity
KYK33_00815	COG1652	LysM domain
KYK33_00820	COG0758	DNA mediated transformation
KYK33_00825	COG2922	Belongs to the Smg family
KYK33_00830	COG0551	DNA topoisomerase type I activity
KYK33_00840	COG0009	L-threonylcarbamoyladenylate synthase
KYK33_00845	COG0408	coproporphyrinogen oxidase activity
KYK33_00850	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
KYK33_00855	COG0218	Necessary for normal cell division and for the maintenance of normal septation
KYK33_00865	COG3078	GTPase activator activity
KYK33_00875	COG0635	Involved in the biosynthesis of porphyrin-containing compound
KYK33_00885	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
KYK33_00890	COG2502	aspartate--ammonia ligase
KYK33_00895	COG1522	sequence-specific DNA binding
KYK33_00905	COG0617	tRNA 3'-terminal CCA addition
KYK33_00905	COG0517	IMP dehydrogenase activity
KYK33_00905	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
KYK33_00925	COG2205	protein histidine kinase activity
KYK33_00935	COG2204	response regulator
KYK33_00945	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
KYK33_00950	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
KYK33_00980	COG0243	molybdopterin cofactor binding
KYK33_00985	COG3005	denitrification pathway
KYK33_00990	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
KYK33_00995	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
KYK33_01000	COG0569	domain protein
KYK33_01005	COG0812	UDP-N-acetylmuramate dehydrogenase activity
KYK33_01030	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
KYK33_01045	COG0250	Participates in transcription elongation, termination and antitermination
KYK33_01050	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
KYK33_01055	COG0081	regulation of translation
KYK33_01060	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
KYK33_01065	COG0222	ribosome binding
KYK33_01070	COG0085	RNA polymerase activity
KYK33_01075	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
KYK33_01080	COG2964	Protein conserved in bacteria
KYK33_01085	COG0251	oxidation-reduction process
KYK33_01100	COG2168	tRNA wobble position uridine thiolation
KYK33_01110	COG0049	tRNA binding
KYK33_01115	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
KYK33_01120	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
KYK33_01125	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
KYK33_01185	COG0583	DNA-binding transcription factor activity
KYK33_01190	COG4221	oxidoreductase activity
KYK33_01205	COG1770	oligopeptidase
KYK33_01225	COG3714	YhhN family
KYK33_01250	COG1301	dicarboxylic acid transport
KYK33_01260	COG2095	MarC family integral membrane protein
KYK33_01275	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
KYK33_01280	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KYK33_01305	COG0742	ribosomal rna small subunit methyltransferase
KYK33_01310	COG0552	protein localization to endoplasmic reticulum
KYK33_01315	COG2884	Cell division ATP-binding protein ftsE
KYK33_01320	COG2177	Part of the ABC transporter FtsEX involved in
KYK33_01330	COG0288	reversible hydration of carbon dioxide
KYK33_01335	COG2188	Transcriptional regulator
KYK33_01340	COG3314	Sporulation integral membrane protein YlbJ
KYK33_01345	COG1228	amidohydrolase
KYK33_01350	COG0010	Belongs to the arginase family
KYK33_01355	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
KYK33_01360	COG2986	histidine ammonia-lyase
KYK33_01365	COG0387	Pfam Sodium calcium exchanger
KYK33_01385	COG3179	chitinase
KYK33_01410	COG3501	Rhs element vgr protein
KYK33_01425	COG1494	fructose-1,6-bisphosphatase
KYK33_01440	COG2959	enzyme of heme biosynthesis
KYK33_01445	COG1587	Uroporphyrinogen-III synthase
KYK33_01450	COG0181	hydroxymethylbilane synthase activity
KYK33_01455	COG3072	Adenylate cyclase
KYK33_01465	COG1965	Belongs to the frataxin family
KYK33_01475	COG0019	diaminopimelate decarboxylase activity
KYK33_01480	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
KYK33_01495	COG1011	Hydrolase
KYK33_01505	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
KYK33_01510	COG0561	phosphatase activity
KYK33_01525	COG0842	Transport permease protein
KYK33_01525	COG1129	ABC transporter
KYK33_01545	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
KYK33_01560	COG0189	ligase activity
KYK33_01580	COG4221	oxidoreductase activity
KYK33_01595	COG1979	alcohol dehydrogenase
KYK33_01605	COG2873	o-acetylhomoserine
KYK33_01620	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
KYK33_01640	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
KYK33_01655	COG2949	membrane
KYK33_01660	COG3291	Pkd domain containing protein
KYK33_01665	COG0318	PFAM AMP-dependent synthetase and ligase
KYK33_01675	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
KYK33_01680	COG0596	Alpha beta hydrolase
KYK33_01685	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
KYK33_01690	COG1169	isochorismate synthase
KYK33_01695	COG1575	Belongs to the MenA family. Type 1 subfamily
KYK33_01705	COG0745	RESPONSE REGULATOR receiver
KYK33_01725	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
KYK33_01730	COG0352	thiamine-phosphate diphosphorylase activity
KYK33_01735	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
KYK33_01745	COG2022	thiamine diphosphate biosynthetic process
KYK33_01755	COG1943	Transposase
KYK33_01760	COG0110	maltose O-acetyltransferase activity
KYK33_01765	COG3417	Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1B (PBP1b)
KYK33_01770	COG3932	Exopolysaccharide synthesis, ExoD
KYK33_01775	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
KYK33_01785	COG1823	symporter activity
KYK33_01810	COG2226	methyltransferase
KYK33_01840	COG4771	TonB-dependent receptor
KYK33_01845	COG1278	Cold shock
KYK33_01870	COG5499	transcription regulator containing HTH domain
KYK33_01875	COG5642	Protein of unknown function (DUF2384)
KYK33_01905	COG2175	clavaminate synthase activity
KYK33_01920	COG2197	response regulator
KYK33_01960	COG3047	cAMP biosynthetic process
KYK33_01965	COG0840	transmembrane signaling receptor activity
KYK33_01970	COG1653	transport
KYK33_01985	COG3135	benzoate transporter
KYK33_01990	COG1396	sequence-specific DNA binding
KYK33_02020	COG2926	Belongs to the UPF0265 family
KYK33_02030	COG3028	Belongs to the UPF0307 family
KYK33_02035	COG0312	modulator of DNA gyrase
KYK33_02040	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
KYK33_02045	COG5007	Belongs to the BolA IbaG family
KYK33_02055	COG2854	intermembrane phospholipid transfer
KYK33_02060	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
KYK33_02065	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
KYK33_02070	COG1127	ABC transporter
KYK33_02075	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
KYK33_02075	COG0517	IMP dehydrogenase activity
KYK33_02080	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
KYK33_02090	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
KYK33_02095	COG1137	ATPase activity
KYK33_02100	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
KYK33_02110	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
KYK33_02115	COG1660	Displays ATPase and GTPase activities
KYK33_02120	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
KYK33_02125	COG3711	transcriptional antiterminator
KYK33_02125	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
KYK33_02140	COG3964	amidohydrolase
KYK33_02170	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KYK33_02175	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KYK33_02185	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
KYK33_02190	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
KYK33_02195	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
KYK33_02200	COG0723	plastoquinol--plastocyanin reductase activity
KYK33_02205	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
KYK33_02210	COG2857	Cytochrome c1
KYK33_02215	COG0625	glutathione transferase activity
KYK33_02220	COG2969	positive regulation of protein catabolic process
KYK33_02225	COG2823	Periplasmic or secreted lipoprotein
KYK33_02230	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
KYK33_02235	COG0792	nuclease activity
KYK33_02240	COG3107	peptidoglycan biosynthetic process
KYK33_02245	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
KYK33_02270	COG1987	bacterial-type flagellum assembly
KYK33_02295	COG1677	Flagellar hook-basal body complex protein FliE
KYK33_02305	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
KYK33_02340	COG1815	bacterial-type flagellum-dependent cell motility
KYK33_02355	COG1749	Flagellar hook protein flgE
KYK33_02365	COG4786	Flagellar basal body rod
KYK33_02370	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
KYK33_02375	COG1706	bacterial-type flagellum-dependent cell motility
KYK33_02385	COG1256	bacterial-type flagellum assembly
KYK33_02385	COG4786	Flagellar basal body rod
KYK33_02405	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
KYK33_02410	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
KYK33_02415	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
KYK33_02440	COG1191	sigma factor activity
KYK33_02445	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
KYK33_02450	COG1360	Flagellar Motor Protein
KYK33_02460	COG1388	LysM domain
KYK33_02460	COG0741	lytic transglycosylase activity
KYK33_02470	COG2001	Belongs to the MraZ family
KYK33_02475	COG0275	rRNA processing
KYK33_02480	COG3116	cell division
KYK33_02485	COG0768	penicillin binding
KYK33_02490	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
KYK33_02495	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
KYK33_02500	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
KYK33_02505	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
KYK33_02510	COG0772	Belongs to the SEDS family
KYK33_02515	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
KYK33_02520	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
KYK33_02525	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
KYK33_02530	COG0849	cell division
KYK33_02535	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
KYK33_02540	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
KYK33_02550	COG0653	protein targeting
KYK33_02560	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
KYK33_02565	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
KYK33_02580	COG1459	type II secretion system
KYK33_02585	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
KYK33_02610	COG2186	Transcriptional regulator
KYK33_02615	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
KYK33_02620	COG0508	dehydrogenase complex catalyzes the overall conversion of
KYK33_02625	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
KYK33_02630	COG0840	transmembrane signaling receptor activity
KYK33_02635	COG0840	transmembrane signaling receptor activity
KYK33_02640	COG1752	Esterase of the alpha-beta hydrolase superfamily
KYK33_02645	COG1049	propionate catabolic process, 2-methylcitrate cycle
KYK33_02650	COG2200	EAL domain
KYK33_02655	COG2200	EAL domain
KYK33_02665	COG0523	cobalamin synthesis protein
KYK33_02670	COG0477	Major facilitator Superfamily
KYK33_02680	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
KYK33_02685	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
KYK33_02690	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
KYK33_02695	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
KYK33_02730	COG1917	Cupin 2, conserved barrel domain protein
KYK33_02730	COG2207	Transcriptional regulator
KYK33_02750	COG0110	maltose O-acetyltransferase activity
KYK33_02755	COG0366	Alpha amylase catalytic
KYK33_02760	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KYK33_02760	COG1263	PTS System
KYK33_02780	COG0252	asparaginase activity
KYK33_02795	COG1803	Methylglyoxal synthase
KYK33_02815	COG1444	tRNA N-acetyltransferase activity
KYK33_02820	COG1757	Na H antiporter
KYK33_02855	COG0297	glycogen (starch) synthase activity
KYK33_02860	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
KYK33_02865	COG2813	Specifically methylates the guanine in position
KYK33_02870	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
KYK33_02875	COG3706	GGDEF domain
KYK33_02875	COG4251	negative regulation of phosphorylation
KYK33_02875	COG5001	Diguanylate cyclase
KYK33_02875	COG2203	Gaf domain
KYK33_02880	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
KYK33_02890	COG2995	paraquat-inducible protein a
KYK33_02895	COG3008	intermembrane lipid transfer
KYK33_02895	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
KYK33_02900	COG3009	Protein conserved in bacteria
KYK33_02910	COG3240	lipase activity
KYK33_02915	COG3111	PFAM Bacterial OB fold (BOF) protein
KYK33_02925	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
KYK33_02930	COG1194	a g-specific adenine glycosylase
KYK33_02940	COG3267	Type II secretory pathway component ExeA
KYK33_02940	COG3409	Peptidoglycan-binding domain 1 protein
KYK33_02945	COG0617	tRNA 3'-terminal CCA addition
KYK33_02950	COG0306	phosphate transporter
KYK33_02955	COG1392	Phosphate transport regulator
KYK33_02960	COG3025	triphosphatase activity
KYK33_02970	COG1560	Kdo2-lipid A biosynthetic process
KYK33_02975	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
KYK33_02975	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
KYK33_02980	COG1538	Outer membrane efflux protein
KYK33_02985	COG0494	nUDIX hydrolase
KYK33_02990	COG3151	Protein conserved in bacteria
KYK33_02995	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
KYK33_03000	COG3150	esterase
KYK33_03005	COG1051	belongs to the nudix hydrolase family
KYK33_03020	COG1566	PFAM secretion protein HlyD family protein
KYK33_03025	COG1289	transmembrane transporter activity
KYK33_03040	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
KYK33_03075	COG0484	heat shock protein binding
KYK33_03085	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KYK33_03105	COG0204	Acyl-transferase
KYK33_03110	COG1842	Phage shock protein A
KYK33_03125	COG2827	Endonuclease containing a URI domain
KYK33_03130	COG2962	Rard protein
KYK33_03135	COG1573	uracil-dna glycosylase
KYK33_03140	COG0697	spore germination
KYK33_03145	COG0583	DNA-binding transcription factor activity
KYK33_03150	COG1108	ABC-type Mn2 Zn2 transport systems permease components
KYK33_03155	COG1121	(ABC) transporter
KYK33_03160	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
KYK33_03180	COG0739	heme binding
KYK33_03185	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
KYK33_03190	COG3068	Protein conserved in bacteria
KYK33_03210	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
KYK33_03215	COG1546	Belongs to the CinA family
KYK33_03220	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
KYK33_03230	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
KYK33_03235	COG0527	aspartate kinase activity
KYK33_03240	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
KYK33_03275	COG1686	Belongs to the peptidase S11 family
KYK33_03280	COG0586	Pfam SNARE associated Golgi protein
KYK33_03285	COG1253	flavin adenine dinucleotide binding
KYK33_03290	COG0525	valine-tRNA ligase activity
KYK33_03300	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
KYK33_03305	COG0795	lipopolysaccharide-transporting ATPase activity
KYK33_03310	COG0795	lipopolysaccharide-transporting ATPase activity
KYK33_03325	COG0004	ammonium transporteR
KYK33_03330	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
KYK33_03340	COG0084	hydrolase, TatD family'
KYK33_03345	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
KYK33_03355	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
KYK33_03360	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
KYK33_03365	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
KYK33_03370	COG0813	purine-nucleoside phosphorylase activity
KYK33_03380	COG3064	Membrane
KYK33_03390	COG0560	Phosphoserine phosphatase
KYK33_03420	COG0776	regulation of translation
KYK33_03435	COG1872	DUF167
KYK33_03440	COG0762	integral membrane protein
KYK33_03445	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
KYK33_03450	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
KYK33_03465	COG3022	response to hydroperoxide
KYK33_03470	COG0513	Belongs to the DEAD box helicase family
KYK33_03475	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
KYK33_03495	COG0735	belongs to the Fur family
KYK33_03500	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
KYK33_03515	COG4166	transmembrane transport
KYK33_03525	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
KYK33_03530	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
KYK33_03535	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
KYK33_03540	COG2204	response regulator
KYK33_03555	COG1024	Enoyl-CoA hydratase
KYK33_03570	COG4221	oxidoreductase activity
KYK33_03575	COG0442	prolyl-tRNA aminoacylation
KYK33_03585	COG0632	four-way junction helicase activity
KYK33_03590	COG2255	four-way junction helicase activity
KYK33_03600	COG1294	oxidase, subunit
KYK33_03605	COG4890	Cyd operon protein YbgT
KYK33_03615	COG0824	Thioesterase
KYK33_03620	COG0811	peptide transport
KYK33_03635	COG0823	Involved in the tonB-independent uptake of proteins
KYK33_03640	COG2885	chlorophyll binding
KYK33_03645	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
KYK33_03720	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
KYK33_03735	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
KYK33_03740	COG1640	4-alpha-glucanotransferase
KYK33_03745	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
KYK33_03770	COG2130	NADP-dependent
KYK33_03775	COG1764	response to oxidative stress
KYK33_03780	COG1846	Transcriptional regulator
KYK33_03795	COG1522	sequence-specific DNA binding
KYK33_03810	COG0561	phosphatase activity
KYK33_03825	COG0733	neurotransmitter:sodium symporter activity
KYK33_03830	COG0733	neurotransmitter:sodium symporter activity
KYK33_03840	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KYK33_03855	COG1794	racemase activity, acting on amino acids and derivatives
KYK33_03865	COG2731	YhcH YjgK YiaL family protein
KYK33_03875	COG0668	transmembrane transport
KYK33_03880	COG1376	ErfK ybiS ycfS ynhG family protein
KYK33_03885	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KYK33_03900	COG0789	Transcriptional regulator
KYK33_03935	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
KYK33_03945	COG0488	(ABC) transporter
KYK33_03955	COG1585	Membrane protein implicated in regulation of membrane protease activity
KYK33_03960	COG0330	HflC and HflK could
KYK33_03965	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
KYK33_03965	COG1648	precorrin-2 dehydrogenase activity
KYK33_03970	COG0175	sulfate reduction
KYK33_03975	COG2895	sulfate adenylyltransferase (ATP) activity
KYK33_03980	COG3273	potassium ion transport
KYK33_03980	COG0471	metal ion transport
KYK33_03985	COG0529	Catalyzes the synthesis of activated sulfate
KYK33_04025	COG4181	ATPase activity
KYK33_04035	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
KYK33_04050	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
KYK33_04055	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
KYK33_04060	COG0163	prenyltransferase activity
KYK33_04075	COG1131	(ABC) transporter
KYK33_04080	COG0842	Transport permease protein
KYK33_04090	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
KYK33_04095	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
KYK33_04100	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
KYK33_04110	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
KYK33_04115	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
KYK33_04120	COG1489	DNA binding
KYK33_04125	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
KYK33_04130	COG1643	Atp-dependent helicase
KYK33_04135	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
KYK33_04140	COG0346	lactoylglutathione lyase activity
KYK33_04155	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
KYK33_04160	COG0038	chloride channel
KYK33_04170	COG0316	Belongs to the HesB IscA family
KYK33_04195	COG1280	lysine exporter protein (LysE YggA)
KYK33_04200	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
KYK33_04205	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
KYK33_04215	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KYK33_04245	COG0745	RESPONSE REGULATOR receiver
KYK33_04250	COG3104	oligopeptide transport
KYK33_04255	COG1210	Utp--glucose-1-phosphate uridylyltransferase
KYK33_04260	COG1555	photosystem II stabilization
KYK33_04270	COG2350	Protein conserved in bacteria
KYK33_04275	COG2917	probably involved in intracellular septation
KYK33_04280	COG0076	glutamate decarboxylase activity
KYK33_04285	COG1272	protein, Hemolysin III
KYK33_04290	COG2985	domain, Protein
KYK33_04290	COG0569	domain protein
KYK33_04300	COG1278	Cold shock
KYK33_04310	COG0840	transmembrane signaling receptor activity
KYK33_04315	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
KYK33_04320	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
KYK33_04355	COG0784	Response regulator, receiver
KYK33_04355	COG0835	chemotaxis
KYK33_04360	COG2755	lipolytic protein G-D-S-L family
KYK33_04365	COG4181	ATPase activity
KYK33_04370	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
KYK33_04375	COG1090	epimerase
KYK33_04380	COG0857	belongs to the CobB CobQ family
KYK33_04380	COG0280	phosphate acetyltransferase
KYK33_04385	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
KYK33_04395	COG3013	Belongs to the UPF0304 family
KYK33_04400	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
KYK33_04405	COG2716	regulation of RNA biosynthetic process
KYK33_04415	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
KYK33_04420	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
KYK33_04435	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
KYK33_04455	COG0784	Response regulator, receiver
KYK33_04455	COG2198	Histidine kinase
KYK33_04455	COG5002	protein histidine kinase activity
KYK33_04460	COG0232	Belongs to the dGTPase family. Type 2 subfamily
KYK33_04490	COG1464	Belongs to the NlpA lipoprotein family
KYK33_04495	COG2011	ABC-type metal ion transport system permease component
KYK33_04515	COG0848	biopolymer transport protein
KYK33_04520	COG0811	peptide transport
KYK33_04525	COG0811	peptide transport
KYK33_04535	COG4206	TonB-dependent receptor
KYK33_04540	COG4174	ABC transporter (Permease)
KYK33_04545	COG4239	(ABC) transporter, permease
KYK33_04555	COG0444	Belongs to the ABC transporter superfamily
KYK33_04560	COG4608	Belongs to the ABC transporter superfamily
KYK33_04565	COG2195	Cleaves the N-terminal amino acid of tripeptides
KYK33_04710	COG4695	Portal protein
KYK33_04725	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
KYK33_04820	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
KYK33_04830	COG4974	Belongs to the 'phage' integrase family
KYK33_04835	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
KYK33_04840	COG1073	alpha beta
KYK33_04850	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
KYK33_04855	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
KYK33_04875	COG0243	molybdopterin cofactor binding
KYK33_04880	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
KYK33_04880	COG1648	precorrin-2 dehydrogenase activity
KYK33_04890	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
KYK33_04890	COG1116	anion transmembrane transporter activity
KYK33_04895	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
KYK33_04900	COG1116	anion transmembrane transporter activity
KYK33_04905	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
KYK33_04905	COG2146	nitrite reductase [NAD(P)H] activity
KYK33_04910	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
KYK33_04910	COG2146	nitrite reductase [NAD(P)H] activity
KYK33_04915	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KYK33_04920	COG2313	pseudouridylate synthase activity
KYK33_04960	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
KYK33_04980	COG2986	histidine ammonia-lyase
KYK33_05005	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
KYK33_05015	COG1028	Short-chain dehydrogenase reductase Sdr
KYK33_05020	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
KYK33_05025	COG0521	Mo-molybdopterin cofactor biosynthetic process
KYK33_05035	COG2966	Psort location CytoplasmicMembrane, score
KYK33_05040	COG3610	response to peptide
KYK33_05050	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
KYK33_05055	COG2967	ApaG domain
KYK33_05060	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
KYK33_05065	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
KYK33_05075	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
KYK33_05080	COG3178	'Phosphotransferase
KYK33_05085	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
KYK33_05090	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
KYK33_05095	COG2252	PERMEase
KYK33_05105	COG0488	(ABC) transporter
KYK33_05110	COG0741	lytic transglycosylase activity
KYK33_05130	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KYK33_05140	COG3721	Heme iron utilization protein
KYK33_05145	COG0748	coenzyme F420 binding
KYK33_05170	COG2814	Major facilitator Superfamily
KYK33_05175	COG2205	protein histidine kinase activity
KYK33_05195	COG1765	OsmC-like protein
KYK33_05200	COG3895	Periplasmic Protein
KYK33_05210	COG3954	Phosphoribulokinase
KYK33_05215	COG3089	Belongs to the UPF0270 family
KYK33_05220	COG5001	Diguanylate cyclase
KYK33_05220	COG4251	negative regulation of phosphorylation
KYK33_05220	COG2203	Gaf domain
KYK33_05220	COG3706	GGDEF domain
KYK33_05225	COG0429	hydrolase of the alpha beta-hydrolase fold
KYK33_05230	COG0835	chemotaxis
KYK33_05230	COG0784	Response regulator, receiver
KYK33_05240	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
KYK33_05245	COG1047	Peptidyl-prolyl cis-trans
KYK33_05260	COG0545	Peptidyl-prolyl cis-trans isomerase
KYK33_05285	COG0737	Belongs to the 5'-nucleotidase family
KYK33_05290	COG0786	glutamate:sodium symporter activity
KYK33_05295	COG0252	asparaginase activity
KYK33_05300	COG3139	Protein of unknown function (DUF1315)
KYK33_05320	COG0616	signal peptide processing
KYK33_05325	COG0446	pyridine nucleotide-disulphide oxidoreductase
KYK33_05325	COG1902	pentaerythritol trinitrate reductase activity
KYK33_05335	COG0778	Nitroreductase
KYK33_05345	COG2264	protein methyltransferase activity
KYK33_05355	COG0583	DNA-binding transcription factor activity
KYK33_05360	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KYK33_05360	COG2190	(PTS) system
KYK33_05360	COG1263	PTS System
KYK33_05365	COG4145	pantothenate transmembrane transporter activity
KYK33_05380	COG3924	membrane
KYK33_05385	COG0439	Biotin carboxylase
KYK33_05390	COG0511	ligase activity, forming carbon-carbon bonds
KYK33_05395	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
KYK33_05400	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
KYK33_05410	COG3381	protein complex oligomerization
KYK33_05420	COG3005	denitrification pathway
KYK33_05425	COG0745	RESPONSE REGULATOR receiver
KYK33_05440	COG1879	ABC-type sugar transport system periplasmic component
KYK33_05445	COG0784	Response regulator, receiver
KYK33_05445	COG2198	Histidine kinase
KYK33_05445	COG2205	protein histidine kinase activity
KYK33_05455	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
KYK33_05465	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
KYK33_05470	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
KYK33_05470	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
KYK33_05485	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
KYK33_05490	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
KYK33_05495	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
KYK33_05500	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
KYK33_05505	COG4172	Belongs to the ABC transporter superfamily
KYK33_05515	COG0601	transmembrane transport
KYK33_05520	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KYK33_05525	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
KYK33_05530	COG0142	geranyltranstransferase activity
KYK33_05535	COG1722	exodeoxyribonuclease VII activity
KYK33_05540	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
KYK33_05545	COG1360	Flagellar Motor Protein
KYK33_05560	COG1534	Rna-binding protein
KYK33_05565	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
KYK33_05575	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
KYK33_05580	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
KYK33_05585	COG0149	triose-phosphate isomerase activity
KYK33_05590	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
KYK33_05605	COG0779	Required for maturation of 30S ribosomal subunits
KYK33_05610	COG0195	Participates in both transcription termination and antitermination
KYK33_05615	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
KYK33_05620	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
KYK33_05625	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
KYK33_05630	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
KYK33_05635	COG1185	polyribonucleotide nucleotidyltransferase activity
KYK33_05640	COG2211	Major facilitator Superfamily
KYK33_05650	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
KYK33_05660	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
KYK33_05665	COG0826	peptidase U32
KYK33_05690	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
KYK33_05695	COG2201	protein-glutamate methylesterase activity
KYK33_05700	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
KYK33_05705	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
KYK33_05710	COG0840	transmembrane signaling receptor activity
KYK33_05715	COG0835	chemotaxis
KYK33_05725	COG2198	Histidine kinase
KYK33_05725	COG0643	Histidine kinase
KYK33_05735	COG0745	RESPONSE REGULATOR receiver
KYK33_05740	COG0840	transmembrane signaling receptor activity
KYK33_05745	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KYK33_05755	COG1280	lysine exporter protein (LysE YggA)
KYK33_05775	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
KYK33_05795	COG0300	oxidoreductase activity
KYK33_05810	COG0697	spore germination
KYK33_05815	COG2610	gluconate transmembrane transporter activity
KYK33_05820	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
KYK33_05825	COG3622	Belongs to the hyi family
KYK33_05830	COG0235	Class ii aldolase
KYK33_05840	COG2084	Dehydrogenase
KYK33_05845	COG1349	DNA-binding transcription factor activity
KYK33_05860	COG2133	pyrroloquinoline quinone binding
KYK33_05865	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
KYK33_05870	COG2375	cellular response to nickel ion
KYK33_05880	COG1021	2,3-dihydroxybenzoate-AMP ligase
KYK33_05885	COG3433	isochorismatase activity
KYK33_05885	COG1535	isochorismatase
KYK33_05890	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KYK33_05895	COG1028	Short-chain dehydrogenase reductase Sdr
KYK33_05905	COG0300	oxidoreductase activity
KYK33_05905	COG0318	PFAM AMP-dependent synthetase and ligase
KYK33_05905	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KYK33_05905	COG1028	Short-chain dehydrogenase reductase Sdr
KYK33_05905	COG3321	synthase
KYK33_05910	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
KYK33_05915	COG2977	Belongs to the P-Pant transferase superfamily
KYK33_05920	COG1120	ATPase activity
KYK33_05925	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KYK33_05930	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KYK33_05935	COG4771	TonB-dependent receptor
KYK33_05945	COG3119	arylsulfatase activity
KYK33_05950	COG0641	radical SAM
KYK33_05955	COG0714	Associated with various cellular activities
KYK33_06010	COG1605	Chorismate mutase
KYK33_06010	COG0077	Prephenate dehydratase
KYK33_06035	COG0789	Transcriptional regulator
KYK33_06050	COG0300	oxidoreductase activity
KYK33_06065	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
KYK33_06090	COG0783	Belongs to the Dps family
KYK33_06095	COG1151	hydroxylamine reductase activity
KYK33_06100	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
KYK33_06100	COG1017	nitric oxide dioxygenase activity
KYK33_06105	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
KYK33_06110	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
KYK33_06110	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
KYK33_06125	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
KYK33_06140	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
KYK33_06180	COG2003	Belongs to the UPF0758 family
KYK33_06220	COG3311	Transcriptional regulator
KYK33_06245	COG0582	viral genome integration into host DNA
KYK33_06255	COG1486	melibiose metabolic process
KYK33_06260	COG1917	Cupin 2, conserved barrel domain protein
KYK33_06260	COG2169	Transcriptional regulator
KYK33_06265	COG1447	Phosphotransferase system cellobiose-specific component IIA
KYK33_06270	COG2723	6-phospho-beta-galactosidase activity
KYK33_06275	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
KYK33_06280	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
KYK33_06285	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
KYK33_06290	COG0583	DNA-binding transcription factor activity
KYK33_06300	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
KYK33_06310	COG0583	DNA-binding transcription factor activity
KYK33_06315	COG1028	Short-chain dehydrogenase reductase Sdr
KYK33_06320	COG0616	signal peptide processing
KYK33_06325	COG3724	N-succinylarginine dihydrolase activity
KYK33_06345	COG0840	transmembrane signaling receptor activity
KYK33_06355	COG2971	BadF BadG BcrA BcrD
KYK33_06365	COG4608	Belongs to the ABC transporter superfamily
KYK33_06370	COG0444	Belongs to the ABC transporter superfamily
KYK33_06375	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KYK33_06425	COG3220	belongs to the UPF0276 family
KYK33_06440	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KYK33_06455	COG1289	transmembrane transporter activity
KYK33_06460	COG1763	Mo-molybdopterin cofactor biosynthetic process
KYK33_06465	COG0746	molybdenum cofactor guanylyltransferase activity
KYK33_06475	COG0281	malic enzyme
KYK33_06510	COG1129	ABC transporter
KYK33_06515	COG1172	Belongs to the binding-protein-dependent transport system permease family
KYK33_06520	COG1472	Belongs to the glycosyl hydrolase 3 family
KYK33_06535	COG1196	nuclear chromosome segregation
KYK33_06535	COG3264	Mechanosensitive ion channel
KYK33_06540	COG0469	pyruvate kinase activity
KYK33_06570	COG2204	response regulator
KYK33_06585	COG2755	lipolytic protein G-D-S-L family
KYK33_06590	COG2974	May be involved in recombination
KYK33_06600	COG0420	3'-5' exonuclease activity
KYK33_06605	COG0419	ATPase involved in DNA repair
KYK33_06610	COG2190	(PTS) system
KYK33_06620	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
KYK33_06625	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
KYK33_06635	COG1720	tRNA m6t6A37 methyltransferase activity
KYK33_06650	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
KYK33_06655	COG4988	ABC transporter
KYK33_06670	COG0745	RESPONSE REGULATOR receiver
KYK33_06675	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
KYK33_06690	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
KYK33_06695	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
KYK33_06705	COG0083	homoserine kinase activity
KYK33_06710	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
KYK33_06715	COG4319	ketosteroid isomerase
KYK33_06720	COG0488	(ABC) transporter
KYK33_06750	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
KYK33_06755	COG0583	DNA-binding transcription factor activity
KYK33_06775	COG1376	ErfK ybiS ycfS ynhG family protein
KYK33_06775	COG1388	LysM domain
KYK33_06800	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
KYK33_06810	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
KYK33_06820	COG1538	Outer membrane efflux protein
KYK33_06825	COG1136	(ABC) transporter
KYK33_06825	COG0577	efflux transmembrane transporter activity
KYK33_06830	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KYK33_06835	COG1227	inorganic diphosphatase activity
KYK33_06840	COG0497	DNA recombination
KYK33_06845	COG3706	GGDEF domain
KYK33_06850	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
KYK33_06855	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
KYK33_06860	COG0443	Heat shock 70 kDa protein
KYK33_06865	COG0484	heat shock protein binding
KYK33_06905	COG0095	Lipoate-protein ligase
KYK33_06915	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
KYK33_06930	COG0708	Exodeoxyribonuclease III
KYK33_06945	COG3241	Transfers electrons from cytochrome c551 to cytochrome oxidase
KYK33_06975	COG3152	Membrane
KYK33_06980	COG0583	DNA-binding transcription factor activity
KYK33_06985	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
KYK33_06990	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
KYK33_06995	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
KYK33_07000	COG1845	cytochrome c oxidase, subunit III
KYK33_07005	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
KYK33_07010	COG0109	protoheme IX farnesyltransferase activity
KYK33_07015	COG2814	Major facilitator Superfamily
KYK33_07020	COG5507	3-demethylubiquinone-9 3-methyltransferase
KYK33_07035	COG3550	peptidyl-serine autophosphorylation
KYK33_07040	COG1396	sequence-specific DNA binding
KYK33_07060	COG0159	tryptophan synthase activity
KYK33_07065	COG0133	tryptophan synthase activity
KYK33_07070	COG0134	indole-3-glycerol-phosphate synthase activity
KYK33_07070	COG0135	phosphoribosylanthranilate isomerase activity
KYK33_07075	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
KYK33_07080	COG0512	Glutamine amidotransferase of anthranilate synthase
KYK33_07080	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
KYK33_07090	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
KYK33_07100	COG0009	L-threonylcarbamoyladenylate synthase
KYK33_07110	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
KYK33_07120	COG1946	Acyl-CoA thioesterase
KYK33_07145	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KYK33_07150	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
KYK33_07160	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
KYK33_07165	COG2867	negative regulation of translational initiation
KYK33_07170	COG2914	Belongs to the UPF0125 (RnfH) family
KYK33_07175	COG0702	epimerase
KYK33_07180	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
KYK33_07190	COG0564	pseudouridine synthase activity
KYK33_07215	COG1280	lysine exporter protein (LysE YggA)
KYK33_07220	COG3263	regulation of cellular component size
KYK33_07230	COG3263	regulation of cellular component size
KYK33_07240	COG1876	peptidase activity
KYK33_07245	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
KYK33_07250	COG1393	Belongs to the ArsC family
KYK33_07270	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
KYK33_07280	COG1902	pentaerythritol trinitrate reductase activity
KYK33_07285	COG4221	oxidoreductase activity
KYK33_07290	COG1064	alcohol dehydrogenase
KYK33_07295	COG0017	Asparaginyl-tRNA synthetase
KYK33_07315	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
KYK33_07320	COG0156	8-amino-7-oxononanoate synthase activity
KYK33_07325	COG2226	methyltransferase
KYK33_07330	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
KYK33_07335	COG0501	Belongs to the peptidase M48B family
KYK33_07340	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
KYK33_07355	COG0534	Mate efflux family protein
KYK33_07390	COG0791	NLP P60 protein
KYK33_07395	COG0583	DNA-binding transcription factor activity
KYK33_07415	COG0500	methyltransferase
KYK33_07420	COG4106	trans-aconitate 2-methyltransferase activity
KYK33_07425	COG1801	Protein of unknown function DUF72
KYK33_07430	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
KYK33_07435	COG0217	transcriptional regulatory protein
KYK33_07440	COG2194	sulfuric ester hydrolase activity
KYK33_07445	COG1846	Transcriptional regulator
KYK33_07445	COG1940	carbohydrate kinase activity
KYK33_07450	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
KYK33_07455	COG0363	glucosamine-6-phosphate deaminase activity
KYK33_07460	COG2190	(PTS) system
KYK33_07460	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KYK33_07460	COG1263	PTS System
KYK33_07480	COG1529	Aldehyde oxidase and xanthine dehydrogenase
KYK33_07480	COG2010	Cytochrome c
KYK33_07485	COG2080	2 iron, 2 sulfur cluster binding
KYK33_07490	COG1529	Aldehyde oxidase and xanthine dehydrogenase
KYK33_07495	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
KYK33_07500	COG0735	belongs to the Fur family
KYK33_07510	COG0716	FMN binding
KYK33_07525	COG0596	Alpha beta hydrolase
KYK33_07530	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
KYK33_07535	COG0033	Phosphoglucomutase
KYK33_07545	COG1846	Transcriptional regulator
KYK33_07550	COG2951	lytic endotransglycosylase activity
KYK33_07555	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
KYK33_07560	COG4136	ATPase activity
KYK33_07565	COG4135	transport system, permease component
KYK33_07570	COG4134	Bacterial extracellular solute-binding protein
KYK33_07580	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
KYK33_07590	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
KYK33_07600	COG0729	surface antigen
KYK33_07605	COG2911	Protein conserved in bacteria
KYK33_07615	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
KYK33_07635	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
KYK33_07640	COG1607	acyl-coa hydrolase
KYK33_07650	COG3021	interspecies interaction between organisms
KYK33_07660	COG0741	lytic transglycosylase activity
KYK33_07660	COG1388	LysM domain
KYK33_07665	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KYK33_07670	COG2226	methyltransferase
KYK33_07675	COG0328	RNA-DNA hybrid ribonuclease activity
KYK33_07690	COG0784	Response regulator, receiver
KYK33_07690	COG3437	response regulator, receiver
KYK33_07695	COG1960	acyl-CoA dehydrogenase activity
KYK33_07700	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
KYK33_07705	COG0121	glutamine amidotransferase
KYK33_07710	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
KYK33_07715	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
KYK33_07720	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
KYK33_07740	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
KYK33_07750	COG0590	tRNA wobble adenosine to inosine editing
KYK33_07755	COG0573	inorganic phosphate transmembrane transporter activity
KYK33_07760	COG0581	inorganic phosphate transmembrane transporter activity
KYK33_07765	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
KYK33_07770	COG0704	Plays a role in the regulation of phosphate uptake
KYK33_07775	COG2207	Transcriptional regulator
KYK33_07780	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KYK33_07785	COG1253	flavin adenine dinucleotide binding
KYK33_07800	COG0531	amino acid
KYK33_07805	COG1126	abc transporter atp-binding protein
KYK33_07810	COG0765	amino acid transport
KYK33_07815	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KYK33_07825	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
KYK33_07860	COG1199	ATP-dependent helicase activity
KYK33_07875	COG1448	Aminotransferase
KYK33_07880	COG0433	COG0433 Predicted ATPase
KYK33_07895	COG0658	competence protein
KYK33_07895	COG2333	competence protein COMEC
KYK33_07900	COG1132	(ABC) transporter
KYK33_07905	COG1663	tetraacyldisaccharide 4'-kinase activity
KYK33_07910	COG2835	tetraacyldisaccharide 4'-kinase activity
KYK33_07915	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
KYK33_07920	COG2197	response regulator
KYK33_07925	COG0322	excinuclease ABC activity
KYK33_07950	COG4737	Cytotoxic translational repressor of toxin-antitoxin stability system
KYK33_07960	COG0604	alcohol dehydrogenase
KYK33_07965	COG1309	transcriptional regulator
KYK33_07970	COG2261	transglycosylase associated protein
KYK33_07975	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
KYK33_07985	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
KYK33_08000	COG2203	Gaf domain
KYK33_08000	COG2199	diguanylate cyclase activity
KYK33_08035	COG2119	membrane
KYK33_08040	COG0023	Translation Initiation Factor
KYK33_08050	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
KYK33_08080	COG4139	cobalamin transport
KYK33_08085	COG4138	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system
KYK33_08095	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
KYK33_08100	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
KYK33_08110	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
KYK33_08115	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
KYK33_08115	COG0047	phosphoribosylformylglycinamidine synthase activity
KYK33_08120	COG1007	ATP synthesis coupled electron transport
KYK33_08125	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
KYK33_08135	COG0713	ATP synthesis coupled electron transport
KYK33_08140	COG0839	Belongs to the complex I subunit 6 family
KYK33_08145	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
KYK33_08150	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
KYK33_08155	COG1034	ATP synthesis coupled electron transport
KYK33_08170	COG0649	NAD binding
KYK33_08170	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
KYK33_08175	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
KYK33_08180	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
KYK33_08185	COG1360	Flagellar Motor Protein
KYK33_08190	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
KYK33_08205	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
KYK33_08215	COG3770	Murein endopeptidase that cleaves the D-alanyl-meso-2,6- diamino-pimelyl amide bond that connects peptidoglycan strands. Likely plays a role in the removal of murein from the sacculus
KYK33_08225	COG0724	RNA recognition motif
KYK33_08230	COG4989	oxidoreductase activity
KYK33_08250	COG0367	asparagine synthase
KYK33_08260	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
KYK33_08260	COG4651	solute:proton antiporter activity
KYK33_08265	COG0647	UMP catabolic process
KYK33_08270	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
KYK33_08275	COG1902	pentaerythritol trinitrate reductase activity
KYK33_08290	COG0247	lactate metabolic process
KYK33_08290	COG0277	FAD linked oxidase domain protein
KYK33_08300	COG2050	protein possibly involved in aromatic compounds catabolism
KYK33_08315	COG2814	Major facilitator Superfamily
KYK33_08330	COG3634	alkyl hydroperoxide reductase activity
KYK33_08340	COG0517	IMP dehydrogenase activity
KYK33_08345	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
KYK33_08350	COG0343	queuine tRNA-ribosyltransferase activity
KYK33_08355	COG1862	Preprotein translocase
KYK33_08360	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
KYK33_08365	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
KYK33_08380	COG0826	peptidase U32
KYK33_08385	COG0826	peptidase U32
KYK33_08390	COG3154	lipid carrier protein
KYK33_08410	COG1104	cysteine desulfurase activity
KYK33_08415	COG0822	iron-sulfur transferase activity
KYK33_08420	COG0316	Belongs to the HesB IscA family
KYK33_08425	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
KYK33_08430	COG0443	Heat shock 70 kDa protein
KYK33_08435	COG0633	Ferredoxin
KYK33_08445	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
KYK33_08450	COG0105	UTP biosynthetic process
KYK33_08455	COG0820	rRNA (adenine-C2-)-methyltransferase activity
KYK33_08470	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
KYK33_08475	COG0124	histidyl-tRNA synthetase
KYK33_08480	COG2976	Protein conserved in bacteria
KYK33_08485	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
KYK33_08490	COG1160	GTP binding
KYK33_08510	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
KYK33_08515	COG0574	Belongs to the PEP-utilizing enzyme family
KYK33_08515	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
KYK33_08520	COG2755	lipolytic protein G-D-S-L family
KYK33_08540	COG1464	Belongs to the NlpA lipoprotein family
KYK33_08550	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
KYK33_08555	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
KYK33_08565	COG0101	tRNA pseudouridine synthase activity
KYK33_08570	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
KYK33_08575	COG0285	dihydrofolate synthase activity
KYK33_08580	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
KYK33_08585	COG2920	part of a sulfur-relay system
KYK33_08590	COG1289	transmembrane transporter activity
KYK33_08595	COG0670	Belongs to the BI1 family
KYK33_08600	COG0583	DNA-binding transcription factor activity
KYK33_08620	COG3706	GGDEF domain
KYK33_08625	COG0564	pseudouridine synthase activity
KYK33_08640	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
KYK33_08650	COG0625	glutathione transferase activity
KYK33_08660	COG0745	RESPONSE REGULATOR receiver
KYK33_08665	COG0583	DNA-binding transcription factor activity
KYK33_08675	COG3300	MHYT domain
KYK33_08675	COG5001	Diguanylate cyclase
KYK33_08680	COG0778	Nitroreductase
KYK33_08695	COG2814	Major facilitator Superfamily
KYK33_08710	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
KYK33_08715	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
KYK33_08720	COG0539	negative regulation of cytoplasmic translation
KYK33_08725	COG0776	regulation of translation
KYK33_08735	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
KYK33_08755	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
KYK33_08760	COG0602	queuosine metabolic process
KYK33_08765	COG3530	Putative quorum-sensing-regulated virulence factor
KYK33_08770	COG2096	Adenosyltransferase
KYK33_08780	COG1757	Na H antiporter
KYK33_08785	COG1435	thymidine kinase activity
KYK33_08805	COG1278	Cold shock
KYK33_08810	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
KYK33_08815	COG0542	response to heat
KYK33_08820	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
KYK33_08825	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
KYK33_08830	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
KYK33_08835	COG3134	Outer membrane lipoprotein
KYK33_08840	COG0492	ferredoxin-NADP+ reductase activity
KYK33_08845	COG0686	Belongs to the AlaDH PNT family
KYK33_08855	COG0531	amino acid
KYK33_08855	COG1674	ftsk spoiiie
KYK33_08860	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
KYK33_08865	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
KYK33_08870	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
KYK33_08875	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
KYK33_08880	COG1286	toxin biosynthetic process
KYK33_08885	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
KYK33_08900	COG4172	Belongs to the ABC transporter superfamily
KYK33_08915	COG4168	peptide transport system, permease
KYK33_08925	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
KYK33_08930	COG1842	Phage shock protein A
KYK33_08945	COG3106	COG3106 Predicted ATPase
KYK33_08950	COG3768	UPF0283 membrane protein
KYK33_08960	COG2154	pterin-4-alpha-carbinolamine dehydratase
KYK33_08980	COG2885	chlorophyll binding
KYK33_08985	COG0861	Integral membrane protein TerC family
KYK33_09000	COG1022	Amp-dependent synthetase and ligase
KYK33_09005	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
KYK33_09010	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KYK33_09015	COG0569	domain protein
KYK33_09015	COG2985	domain, Protein
KYK33_09025	COG0556	nucleotide-excision repair
KYK33_09035	COG0586	Pfam SNARE associated Golgi protein
KYK33_09040	COG1944	ATP diphosphatase activity
KYK33_09055	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
KYK33_09070	COG2199	diguanylate cyclase activity
KYK33_09075	COG2910	NAD(P)H-binding
KYK33_09080	COG0583	DNA-binding transcription factor activity
KYK33_09085	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
KYK33_09110	COG0254	rRNA binding
KYK33_09115	COG0257	Belongs to the bacterial ribosomal protein bL36 family
KYK33_09125	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
KYK33_09130	COG0436	Aminotransferase
KYK33_09135	COG0583	DNA-binding transcription factor activity
KYK33_09150	COG1451	nucleotide metabolic process
KYK33_09165	COG3069	C4-dicarboxylate transmembrane transporter activity
KYK33_09175	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
KYK33_09175	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KYK33_09180	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
KYK33_09190	COG3123	guanosine phosphorylase activity
KYK33_09195	COG1301	dicarboxylic acid transport
KYK33_09200	COG0789	Transcriptional regulator
KYK33_09210	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
KYK33_09215	COG2067	long-chain fatty acid transport protein
KYK33_09220	COG2067	long-chain fatty acid transport protein
KYK33_09230	COG1595	DNA-templated transcription, initiation
KYK33_09260	COG0714	Associated with various cellular activities
KYK33_09265	COG0183	Belongs to the thiolase family
KYK33_09270	COG1250	3-hydroxyacyl-CoA dehydrogenase
KYK33_09270	COG1024	Enoyl-CoA hydratase
KYK33_09280	COG4681	YaeQ
KYK33_09285	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
KYK33_09290	COG2894	cell division
KYK33_09295	COG0850	regulation of cytokinetic process
KYK33_09300	COG3100	YcgL domain-containing protein
KYK33_09305	COG1760	l-serine dehydratase
KYK33_09310	COG1760	l-serine dehydratase
KYK33_09315	COG0814	amino acid
KYK33_09345	COG0058	SHG alpha-glucan phosphorylase activity
KYK33_09355	COG0471	metal ion transport
KYK33_09360	COG3118	belongs to the thioredoxin family
KYK33_09370	COG1132	(ABC) transporter
KYK33_09375	COG1132	(ABC) transporter
KYK33_09390	COG2501	S4 domain
KYK33_09415	COG3842	ATPase activity
KYK33_09420	COG1840	ABC-type Fe3 transport system, periplasmic component
KYK33_09425	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
KYK33_09430	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
KYK33_09435	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KYK33_09470	COG0534	Mate efflux family protein
KYK33_09480	COG0307	riboflavin synthase, alpha
KYK33_09490	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
KYK33_09495	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
KYK33_09500	COG0697	spore germination
KYK33_09505	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
KYK33_09545	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
KYK33_09550	COG3099	Belongs to the UPF0263 family
KYK33_09555	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
KYK33_09560	COG2329	Antibiotic biosynthesis monooxygenase
KYK33_09580	COG1742	UPF0060 membrane protein
KYK33_09600	COG0513	Belongs to the DEAD box helicase family
KYK33_09605	COG0386	Belongs to the glutathione peroxidase family
KYK33_09615	COG1181	Belongs to the D-alanine--D-alanine ligase family
KYK33_09625	COG3148	PFAM DTW domain containing protein
KYK33_09630	COG0730	response to heat
KYK33_09635	COG0583	DNA-binding transcription factor activity
KYK33_09640	COG0697	spore germination
KYK33_09650	COG3593	DNA synthesis involved in DNA repair
KYK33_09700	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
KYK33_09705	COG1011	Hydrolase
KYK33_09710	COG1473	amidohydrolase
KYK33_09720	COG0617	tRNA 3'-terminal CCA addition
KYK33_09720	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
KYK33_09720	COG3620	sequence-specific DNA binding
KYK33_09725	COG1643	Atp-dependent helicase
KYK33_09735	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
KYK33_09740	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KYK33_09745	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
KYK33_09750	COG0709	Synthesizes selenophosphate from selenide and ATP
KYK33_09760	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
KYK33_09765	COG0840	transmembrane signaling receptor activity
KYK33_09770	COG1254	Belongs to the acylphosphatase family
KYK33_09780	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KYK33_09780	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KYK33_09785	COG0489	protein tyrosine kinase activity
KYK33_09790	COG0572	uridine kinase
KYK33_09795	COG0717	Belongs to the dCTP deaminase family
KYK33_09800	COG0306	phosphate transporter
KYK33_09805	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
KYK33_09810	COG3067	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
KYK33_09820	COG2719	SpoVR family
KYK33_09825	COG2718	Belongs to the UPF0229 family
KYK33_09830	COG2766	serine protein kinase
KYK33_09835	COG0514	ATP-dependent DNA helicase (RecQ)
KYK33_09840	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
KYK33_09845	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
KYK33_09850	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KYK33_09855	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KYK33_09865	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
KYK33_09885	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
KYK33_09890	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
KYK33_09895	COG0291	Belongs to the bacterial ribosomal protein bL35 family
KYK33_09900	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
KYK33_09905	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
KYK33_09910	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KYK33_09910	COG0072	phenylalanine-tRNA ligase activity
KYK33_09915	COG0776	regulation of translation
KYK33_09945	COG5001	Diguanylate cyclase
KYK33_09950	COG1609	Transcriptional regulator
KYK33_09955	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KYK33_09960	COG1879	ABC-type sugar transport system periplasmic component
KYK33_09965	COG1172	Belongs to the binding-protein-dependent transport system permease family
KYK33_09970	COG1129	ABC transporter
KYK33_09975	COG1869	D-ribose catabolic process
KYK33_09980	COG0625	glutathione transferase activity
KYK33_09995	COG0037	tRNA processing
KYK33_10000	COG0589	response to stress
KYK33_10005	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
KYK33_10030	COG2010	Cytochrome c
KYK33_10045	COG3278	Belongs to the heme-copper respiratory oxidase family
KYK33_10055	COG1956	GAF domain-containing protein
KYK33_10060	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
KYK33_10065	COG0793	Belongs to the peptidase S41A family
KYK33_10070	COG0308	aminopeptidase N
KYK33_10080	COG2902	Dehydrogenase
KYK33_10085	COG0167	dihydroorotate dehydrogenase activity
KYK33_10095	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
KYK33_10095	COG0116	Belongs to the methyltransferase superfamily
KYK33_10105	COG0488	(ABC) transporter
KYK33_10120	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
KYK33_10125	COG1067	ATP-dependent peptidase activity
KYK33_10140	COG4128	Pfam Zonular occludens toxin
KYK33_10250	COG3141	response to X-ray
KYK33_10260	COG2995	paraquat-inducible protein a
KYK33_10265	COG3008	intermembrane lipid transfer
KYK33_10270	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
KYK33_10270	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
KYK33_10285	COG0084	hydrolase, TatD family'
KYK33_10290	COG0470	DNA polymerase III
KYK33_10295	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
KYK33_10300	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
KYK33_10305	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
KYK33_10310	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
KYK33_10315	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
KYK33_10330	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KYK33_10335	COG0416	fatty acid biosynthetic process
KYK33_10340	COG0333	Belongs to the bacterial ribosomal protein bL32 family
KYK33_10345	COG1399	metal-binding, possibly nucleic acid-binding protein
KYK33_10355	COG0546	phosphoglycolate phosphatase activity
KYK33_10360	COG0564	pseudouridine synthase activity
KYK33_10365	COG1530	ribonuclease E activity
KYK33_10370	COG2983	Belongs to the UPF0260 family
KYK33_10380	COG0045	succinate-CoA ligase (ADP-forming) activity
KYK33_10385	COG0508	dehydrogenase complex catalyzes the overall conversion of
KYK33_10390	COG0567	Dehydrogenase, E1 component
KYK33_10400	COG1053	succinate dehydrogenase
KYK33_10405	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
KYK33_10425	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
KYK33_10430	COG4166	transmembrane transport
KYK33_10435	COG0697	spore germination
KYK33_10445	COG2062	phosphohistidine phosphatase, SixA
KYK33_10455	COG0500	methyltransferase
KYK33_10505	COG0518	GMP synthase (glutamine-hydrolyzing) activity
KYK33_10505	COG0519	Catalyzes the synthesis of GMP from XMP
KYK33_10510	COG0516	GMP reductase activity
KYK33_10510	COG0517	IMP dehydrogenase activity
KYK33_10540	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
KYK33_10545	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
KYK33_10550	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
KYK33_10585	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
KYK33_10590	COG3313	Fe-S protein
KYK33_10595	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
KYK33_10595	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
KYK33_10595	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
KYK33_10600	COG1105	Belongs to the carbohydrate kinase PfkB family
KYK33_10605	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
KYK33_10605	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
KYK33_10610	COG1609	Transcriptional regulator
KYK33_10615	COG0814	amino acid
KYK33_10625	COG5654	RES domain protein
KYK33_10630	COG0513	Belongs to the DEAD box helicase family
KYK33_10635	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
KYK33_10640	COG2890	protein-(glutamine-N5) methyltransferase activity
KYK33_10645	COG2840	Smr protein MutS2
KYK33_10675	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
KYK33_10685	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
KYK33_10690	COG2832	Protein of unknown function (DUF454)
KYK33_10695	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
KYK33_10710	COG0318	PFAM AMP-dependent synthetase and ligase
KYK33_10715	COG2267	carboxylic ester hydrolase activity
KYK33_10725	COG1214	PFAM Peptidase M22, glycoprotease
KYK33_10730	COG1199	ATP-dependent helicase activity
KYK33_10740	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
KYK33_10745	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
KYK33_10750	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
KYK33_10755	COG0131	Imidazoleglycerol-phosphate dehydratase
KYK33_10755	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
KYK33_10760	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
KYK33_10765	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
KYK33_10770	COG0107	imidazoleglycerol-phosphate synthase activity
KYK33_10775	COG0140	phosphoribosyl-ATP diphosphatase activity
KYK33_10775	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
KYK33_10790	COG3134	Outer membrane lipoprotein
KYK33_10805	COG3188	usher protein
KYK33_10810	COG3121	Chaperone
KYK33_10840	COG2824	Alkylphosphonate utilization operon protein PhnA
KYK33_10855	COG1280	lysine exporter protein (LysE YggA)
KYK33_10865	COG0384	phenazine biosynthesis protein PhzF
KYK33_10880	COG0588	phosphoglycerate mutase activity
KYK33_10900	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
KYK33_10905	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
KYK33_10915	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
KYK33_10920	COG1335	isochorismatase
KYK33_10925	COG1335	isochorismatase
KYK33_10935	COG0583	DNA-binding transcription factor activity
KYK33_10940	COG1434	Gram-negative-bacterium-type cell wall biogenesis
KYK33_10950	COG0205	6-phosphofructokinase activity
KYK33_10965	COG0417	DNA replication proofreading
KYK33_10990	COG1560	Kdo2-lipid A biosynthetic process
KYK33_10995	COG1560	Kdo2-lipid A biosynthetic process
KYK33_11030	COG0840	transmembrane signaling receptor activity
KYK33_11035	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KYK33_11045	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
KYK33_11050	COG0563	adenylate kinase activity
KYK33_11055	COG0326	Molecular chaperone. Has ATPase activity
KYK33_11060	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
KYK33_11065	COG5001	Diguanylate cyclase
KYK33_11065	COG3300	MHYT domain
KYK33_11070	COG2925	Exonuclease
KYK33_11085	COG1380	Effector of murein hydrolase LrgA
KYK33_11090	COG1346	cytolysis
KYK33_11095	COG0295	cytidine deaminase activity
KYK33_11100	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
KYK33_11105	COG0776	regulation of translation
KYK33_11110	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
KYK33_11115	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
KYK33_11120	COG0740	serine-type endopeptidase activity
KYK33_11125	COG0544	peptidyl-prolyl cis-trans isomerase activity
KYK33_11135	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
KYK33_11140	COG4591	ABC-type transport system involved in lipoprotein release permease component
KYK33_11145	COG1136	(ABC) transporter
KYK33_11150	COG4591	ABC-type transport system involved in lipoprotein release permease component
KYK33_11160	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
KYK33_11165	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
KYK33_11180	COG2199	diguanylate cyclase activity
KYK33_11185	COG0583	DNA-binding transcription factor activity
KYK33_11195	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
KYK33_11245	COG4104	PAAR repeat-containing protein
KYK33_11280	COG3829	transcription factor binding
KYK33_11345	COG0656	L-ascorbic acid biosynthetic process
KYK33_11365	COG0667	Aldo Keto reductase
KYK33_11370	COG1979	alcohol dehydrogenase
KYK33_11375	COG0583	DNA-binding transcription factor activity
KYK33_11385	COG0583	DNA-binding transcription factor activity
KYK33_11395	COG0730	response to heat
KYK33_11405	COG1028	Short-chain dehydrogenase reductase Sdr
KYK33_11415	COG1024	Enoyl-CoA hydratase
KYK33_11420	COG1024	Enoyl-CoA hydratase
KYK33_11425	COG1960	acyl-CoA dehydrogenase activity
KYK33_11435	COG1960	acyl-CoA dehydrogenase activity
KYK33_11440	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
KYK33_11445	COG1024	Enoyl-CoA hydratase
KYK33_11445	COG1250	3-hydroxyacyl-CoA dehydrogenase
KYK33_11470	COG1584	GPR1 FUN34 yaaH family protein
KYK33_11485	COG1115	amino acid carrier protein
KYK33_11490	COG1024	Enoyl-CoA hydratase
KYK33_11505	COG3162	membrane
KYK33_11510	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KYK33_11515	COG0488	(ABC) transporter
KYK33_11520	COG2116	formate transmembrane transporter activity
KYK33_11525	COG1882	Formate acetyltransferase
KYK33_11530	COG3181	Tripartite tricarboxylate transporter family receptor
KYK33_11545	COG4565	transcriptional regulatory protein
KYK33_11550	COG3290	protein histidine kinase activity
KYK33_11555	COG1940	carbohydrate kinase activity
KYK33_11555	COG1846	Transcriptional regulator
KYK33_11560	COG3012	SEC-C Motif Domain Protein
KYK33_11570	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
KYK33_11575	COG3075	Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses fumarate or nitrate as electron acceptor
KYK33_11580	COG0247	lactate metabolic process
KYK33_11585	COG1686	Belongs to the peptidase S11 family
KYK33_11590	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KYK33_11610	COG0517	IMP dehydrogenase activity
KYK33_11610	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
KYK33_11610	COG0617	tRNA 3'-terminal CCA addition
KYK33_11615	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
KYK33_11620	COG0583	DNA-binding transcription factor activity
KYK33_11630	COG4774	siderophore transport
KYK33_11635	COG3708	Transcriptional regulator
KYK33_11635	COG2207	Transcriptional regulator
KYK33_11650	COG0659	secondary active sulfate transmembrane transporter activity
KYK33_11655	COG1757	Na H antiporter
KYK33_11685	COG0672	)-iron permease
KYK33_11690	COG0493	'glutamate synthase
KYK33_11690	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
KYK33_11710	COG2814	Major facilitator Superfamily
KYK33_11735	COG0577	efflux transmembrane transporter activity
KYK33_11755	COG2315	Protein conserved in bacteria
KYK33_11760	COG0454	-acetyltransferase
KYK33_11775	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
KYK33_11775	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
KYK33_11780	COG0527	aspartate kinase activity
KYK33_11790	COG1368	sulfuric ester hydrolase activity
KYK33_11795	COG1619	proteins homologs of microcin C7 resistance protein MccF
KYK33_11800	COG0393	Putative heavy-metal-binding
KYK33_11805	COG1252	NADH dehydrogenase
KYK33_11810	COG3150	esterase
KYK33_11815	COG3706	GGDEF domain
KYK33_11830	COG2354	Protein conserved in bacteria
KYK33_11840	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
KYK33_11845	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
KYK33_11880	COG0537	adenosine 5'-monophosphoramidase activity
KYK33_11895	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
KYK33_11910	COG1301	dicarboxylic acid transport
KYK33_11915	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
KYK33_11920	COG0861	Integral membrane protein TerC family
KYK33_11930	COG0444	Belongs to the ABC transporter superfamily
KYK33_11935	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KYK33_11940	COG0601	transmembrane transport
KYK33_11950	COG2095	MarC family integral membrane protein
KYK33_11960	COG1012	belongs to the aldehyde dehydrogenase family
KYK33_11960	COG1454	alcohol dehydrogenase
KYK33_11965	COG2199	diguanylate cyclase activity
KYK33_11965	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
KYK33_11970	COG3275	phosphorelay sensor kinase activity
KYK33_11975	COG3279	Response regulator of the LytR AlgR family
KYK33_11980	COG1966	Carbon starvation protein
KYK33_11985	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
KYK33_11985	COG3264	Mechanosensitive ion channel
KYK33_11995	COG1566	PFAM secretion protein HlyD family protein
KYK33_12000	COG1061	Type III restriction enzyme res subunit
KYK33_12005	COG2027	D-alanyl-D-alanine carboxypeptidase
KYK33_12010	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
KYK33_12020	COG0436	Aminotransferase
KYK33_12025	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
KYK33_12055	COG2207	Transcriptional regulator
KYK33_12065	COG4657	Part of a membrane complex involved in electron transport
KYK33_12070	COG2878	Part of a membrane complex involved in electron transport
KYK33_12075	COG4656	Part of a membrane complex involved in electron transport
KYK33_12080	COG4658	electron transport chain
KYK33_12085	COG4659	FMN binding
KYK33_12090	COG4660	Part of a membrane complex involved in electron transport
KYK33_12095	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
KYK33_12100	COG0346	lactoylglutathione lyase activity
KYK33_12110	COG2885	chlorophyll binding
KYK33_12115	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
KYK33_12120	COG2056	Na+-H+ antiporter family
KYK33_12140	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
KYK33_12140	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
KYK33_12145	COG0509	glycine decarboxylation via glycine cleavage system
KYK33_12150	COG0404	The glycine cleavage system catalyzes the degradation of glycine
KYK33_12155	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
KYK33_12160	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
KYK33_12165	COG3079	Belongs to the UPF0149 family
KYK33_12180	COG0243	molybdopterin cofactor binding
KYK33_12185	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
KYK33_12190	COG0583	DNA-binding transcription factor activity
KYK33_12195	COG2814	Major facilitator Superfamily
KYK33_12205	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KYK33_12210	COG0601	transmembrane transport
KYK33_12215	COG4166	transmembrane transport
KYK33_12220	COG0625	glutathione transferase activity
KYK33_12225	COG0625	glutathione transferase activity
KYK33_12230	COG1309	transcriptional regulator
KYK33_12240	COG0483	inositol monophosphate 1-phosphatase activity
KYK33_12250	COG0673	inositol 2-dehydrogenase activity
KYK33_12270	COG0789	Transcriptional regulator
KYK33_12290	COG4104	PAAR repeat-containing protein
KYK33_12300	COG0513	Belongs to the DEAD box helicase family
KYK33_12325	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
KYK33_12330	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
KYK33_12335	COG0505	Belongs to the CarA family
KYK33_12340	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
KYK33_12350	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
KYK33_12355	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
KYK33_12360	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
KYK33_12425	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KYK33_12435	COG1242	4 iron, 4 sulfur cluster binding
KYK33_12440	COG0069	glutamate synthase activity
KYK33_12440	COG0070	glutamate synthase
KYK33_12440	COG0067	glutamate synthase
KYK33_12445	COG0493	'glutamate synthase
KYK33_12450	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
KYK33_12460	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
KYK33_12470	COG1086	Polysaccharide biosynthesis protein
KYK33_12475	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
KYK33_12480	COG1083	cytidylyl-transferase
KYK33_12485	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
KYK33_12490	COG3980	spore coat polysaccharide biosynthesis protein
KYK33_12495	COG2089	acid synthase
KYK33_12505	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
KYK33_12560	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
KYK33_12575	COG0301	tRNA thio-modification
KYK33_12575	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KYK33_12595	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
KYK33_12625	COG2431	L-lysine efflux transmembrane transporter activity
KYK33_12630	COG3124	Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP
KYK33_12640	COG1393	Belongs to the ArsC family
KYK33_12650	COG4783	chaperone-mediated protein folding
KYK33_12655	COG0425	Belongs to the sulfur carrier protein TusA family
KYK33_12670	COG2267	carboxylic ester hydrolase activity
KYK33_12680	COG3842	ATPase activity
KYK33_12685	COG3833	ABC-type maltose transport systems, permease component
KYK33_12690	COG1175	transmembrane transport
KYK33_12700	COG3081	Nucleoid-associated protein
KYK33_12705	COG3082	Protein of unknown function (DUF1414)
KYK33_12710	COG3083	sulfuric ester hydrolase activity
KYK33_12715	COG4771	TonB-dependent receptor
KYK33_12720	COG1770	oligopeptidase
KYK33_12740	COG4574	serine-type endopeptidase inhibitor activity
KYK33_12745	COG3085	chromosome segregation
KYK33_12750	COG0583	DNA-binding transcription factor activity
KYK33_12755	COG0287	Prephenate dehydrogenase
KYK33_12755	COG1605	Chorismate mutase
KYK33_12760	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
KYK33_12765	COG0584	glycerophosphoryl diester phosphodiesterase
KYK33_12770	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
KYK33_12775	COG1349	DNA-binding transcription factor activity
KYK33_12780	COG2271	Major facilitator Superfamily
KYK33_12785	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
KYK33_12790	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
KYK33_12795	COG0583	DNA-binding transcription factor activity
KYK33_12820	COG0656	L-ascorbic acid biosynthetic process
KYK33_12825	COG2814	Major facilitator Superfamily
KYK33_12835	COG1294	oxidase, subunit
KYK33_12845	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KYK33_12880	COG0583	DNA-binding transcription factor activity
KYK33_12890	COG2807	transmembrane transport
KYK33_12895	COG1187	pseudouridine synthase activity
KYK33_12900	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
KYK33_12910	COG3813	Protein conserved in bacteria
KYK33_12935	COG1166	arginine decarboxylase activity
KYK33_12940	COG2195	Cleaves the N-terminal amino acid of tripeptides
KYK33_12970	COG0583	DNA-binding transcription factor activity
KYK33_12980	COG2759	Belongs to the formate--tetrahydrofolate ligase family
KYK33_12985	COG0840	transmembrane signaling receptor activity
KYK33_12990	COG0840	transmembrane signaling receptor activity
KYK33_12995	COG0302	gtp cyclohydrolase
KYK33_13005	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
KYK33_13025	COG3119	arylsulfatase activity
KYK33_13030	COG0641	radical SAM
KYK33_13045	COG2267	carboxylic ester hydrolase activity
KYK33_13050	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
KYK33_13065	COG0314	molybdopterin synthase activity
KYK33_13070	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
KYK33_13075	COG0315	cyclic pyranopterin monophosphate synthase activity
KYK33_13080	COG0521	Mo-molybdopterin cofactor biosynthetic process
KYK33_13085	COG3005	denitrification pathway
KYK33_13095	COG0243	molybdopterin cofactor binding
KYK33_13110	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
KYK33_13115	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
KYK33_13120	COG3850	Histidine kinase
KYK33_13125	COG2197	response regulator
KYK33_13130	COG2916	Histone family protein nucleoid-structuring protein H-NS
KYK33_13175	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
KYK33_13205	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
KYK33_13215	COG2239	Acts as a magnesium transporter
KYK33_13225	COG1256	bacterial-type flagellum assembly
KYK33_13230	COG1705	Flagellar rod assembly protein muramidase FlgJ
KYK33_13230	COG3951	Flagellar rod assembly protein muramidase FlgJ
KYK33_13235	COG1706	bacterial-type flagellum-dependent cell motility
KYK33_13240	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
KYK33_13250	COG4787	bacterial-type flagellum-dependent cell motility
KYK33_13270	COG1815	bacterial-type flagellum-dependent cell motility
KYK33_13280	COG0784	Response regulator, receiver
KYK33_13280	COG0835	chemotaxis
KYK33_13285	COG1261	Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly
KYK33_13300	COG0622	Phosphoesterase
KYK33_13305	COG4166	transmembrane transport
KYK33_13315	COG1187	pseudouridine synthase activity
KYK33_13330	COG0697	spore germination
KYK33_13335	COG4166	transmembrane transport
KYK33_13360	COG1278	Cold shock
KYK33_13380	COG2988	succinylglutamate desuccinylase activity
KYK33_13395	COG2197	response regulator
KYK33_13405	COG2271	Major facilitator Superfamily
KYK33_13415	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
KYK33_13420	COG3132	Protein of unknown function, DUF480
KYK33_13465	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
KYK33_13475	COG4641	Protein conserved in bacteria
KYK33_13475	COG0438	transferase activity, transferring glycosyl groups
KYK33_13485	COG0110	maltose O-acetyltransferase activity
KYK33_13490	COG1216	Glycosyl transferase, family 2
KYK33_13505	COG1216	Glycosyl transferase, family 2
KYK33_13505	COG0463	Glycosyl transferase, family 2
KYK33_13520	COG0297	glycogen (starch) synthase activity
KYK33_13535	COG1091	dTDP-4-dehydrorhamnose reductase activity
KYK33_13545	COG0538	isocitrate dehydrogenase activity
KYK33_13550	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
KYK33_13555	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KYK33_13570	COG2207	Transcriptional regulator
KYK33_13575	COG1482	cell wall glycoprotein biosynthetic process
KYK33_13580	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
KYK33_13585	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KYK33_13585	COG1263	PTS System
KYK33_13590	COG1609	Transcriptional regulator
KYK33_13600	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
KYK33_13600	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
KYK33_13600	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
KYK33_13605	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
KYK33_13615	COG1187	pseudouridine synthase activity
KYK33_13625	COG0482	sulfurtransferase activity
KYK33_13630	COG2915	High frequency lysogenization protein hflD homolog
KYK33_13635	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
KYK33_13640	COG2850	peptidyl-arginine hydroxylation
KYK33_13645	COG3153	acetyltransferase
KYK33_13655	COG0259	pyridoxamine-phosphate oxidase activity
KYK33_13670	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
KYK33_13670	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
KYK33_13675	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
KYK33_13690	COG3088	subunit of a heme lyase
KYK33_13690	COG4235	cytochrome complex assembly
KYK33_13695	COG3088	subunit of a heme lyase
KYK33_13695	COG4235	cytochrome complex assembly
KYK33_13700	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KYK33_13705	COG1138	Cytochrome C-type biogenesis protein
KYK33_13710	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
KYK33_13715	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
KYK33_13720	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
KYK33_13725	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
KYK33_13740	COG0835	chemotaxis
KYK33_13750	COG1192	Involved in chromosome partitioning
KYK33_13755	COG1360	Flagellar Motor Protein
KYK33_13760	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
KYK33_13765	COG2201	protein-glutamate methylesterase activity
KYK33_13770	COG0643	Histidine kinase
KYK33_13770	COG0784	Response regulator, receiver
KYK33_13770	COG2198	Histidine kinase
KYK33_13775	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
KYK33_13800	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
KYK33_13810	COG1684	flagellar biosynthetic protein fliR
KYK33_13865	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
KYK33_13890	COG1393	Belongs to the ArsC family
KYK33_13895	COG0798	PFAM Bile acid sodium symporter
KYK33_13905	COG0659	secondary active sulfate transmembrane transporter activity
KYK33_13915	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
KYK33_13980	COG0837	glucose binding
KYK33_13985	COG1737	Transcriptional regulator
KYK33_13990	COG0469	pyruvate kinase activity
KYK33_14000	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
KYK33_14005	COG1960	acyl-CoA dehydrogenase activity
KYK33_14015	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
KYK33_14030	COG1074	ATP-dependent DNA helicase activity
KYK33_14040	COG2189	Belongs to the N(4) N(6)-methyltransferase family
KYK33_14055	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
KYK33_14090	COG2003	Belongs to the UPF0758 family
KYK33_14140	COG4983	Phage plasmid primase, P4 family domain protein
KYK33_14190	COG2723	6-phospho-beta-galactosidase activity
KYK33_14205	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KYK33_14210	COG1012	belongs to the aldehyde dehydrogenase family
KYK33_14225	COG0531	amino acid
KYK33_14240	COG1283	sodium-dependent phosphate transmembrane transporter activity
KYK33_14245	COG0545	Peptidyl-prolyl cis-trans isomerase
KYK33_14250	COG3384	dioxygenase
KYK33_14255	COG0673	inositol 2-dehydrogenase activity
KYK33_14260	COG0406	alpha-ribazole phosphatase activity
KYK33_14270	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
KYK33_14280	COG1032	radical SAM domain protein
KYK33_14290	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
KYK33_14295	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KYK33_14300	COG1752	Esterase of the alpha-beta hydrolase superfamily
KYK33_14305	COG0733	neurotransmitter:sodium symporter activity
KYK33_14335	COG0281	malic enzyme
KYK33_14340	COG2207	Transcriptional regulator
KYK33_14345	COG0534	Mate efflux family protein
KYK33_14360	COG2233	PERMEase
KYK33_14365	COG0095	Lipoate-protein ligase
KYK33_14370	COG1115	amino acid carrier protein
KYK33_14375	COG0019	diaminopimelate decarboxylase activity
KYK33_14385	COG0678	peroxiredoxin activity
KYK33_14395	COG1126	abc transporter atp-binding protein
KYK33_14400	COG0765	amino acid transport
KYK33_14405	COG4597	amino acid ABC transporter
KYK33_14410	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KYK33_14430	COG1131	(ABC) transporter
KYK33_14435	COG0545	Peptidyl-prolyl cis-trans isomerase
KYK33_14465	COG5002	protein histidine kinase activity
KYK33_14470	COG0745	RESPONSE REGULATOR receiver
KYK33_14475	COG0346	lactoylglutathione lyase activity
KYK33_14485	COG3129	Specifically methylates the adenine in position 1618 of 23S rRNA
KYK33_14490	COG0791	NLP P60 protein
KYK33_14500	COG3118	belongs to the thioredoxin family
KYK33_14510	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
KYK33_14515	COG0788	formyltetrahydrofolate deformylase activity
KYK33_14530	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KYK33_14545	COG0741	lytic transglycosylase activity
KYK33_14550	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
KYK33_14555	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
KYK33_14560	COG3706	GGDEF domain
KYK33_14565	COG3284	Transcriptional regulator
KYK33_14580	COG0697	spore germination
KYK33_14585	COG1846	Transcriptional regulator
KYK33_14590	COG1566	PFAM secretion protein HlyD family protein
KYK33_14610	COG0602	queuosine metabolic process
KYK33_14620	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
KYK33_14630	COG1196	nuclear chromosome segregation
KYK33_14640	COG2860	membrane
KYK33_14650	COG3108	Peptidase M15
KYK33_14655	COG2989	Protein conserved in bacteria
KYK33_14670	COG0463	Glycosyl transferase, family 2
KYK33_14685	COG0366	Alpha amylase catalytic
KYK33_14710	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
KYK33_14720	COG0463	Glycosyl transferase, family 2
KYK33_14735	COG3706	GGDEF domain
KYK33_14740	COG0037	tRNA processing
KYK33_14745	COG3590	peptidase
KYK33_14755	COG0488	(ABC) transporter
KYK33_14760	COG0531	amino acid
KYK33_14765	COG1522	sequence-specific DNA binding
KYK33_14770	COG0814	amino acid
KYK33_14785	COG0825	malonyl-CoA metabolic process
KYK33_14795	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
KYK33_14800	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
KYK33_14805	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
KYK33_14810	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
KYK33_14815	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
KYK33_14825	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
KYK33_14830	COG0750	zinc metalloprotease
KYK33_14835	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
KYK33_14840	COG0575	Belongs to the CDS family
KYK33_14845	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
KYK33_14850	COG0233	cytoplasmic translational termination
KYK33_14855	COG0528	UMP kinase activity
KYK33_14860	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
KYK33_14865	COG0052	Belongs to the universal ribosomal protein uS2 family
KYK33_14870	COG0024	Methionine aminopeptidase
KYK33_14875	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
KYK33_14880	COG2171	N-acyltransferase activity
KYK33_14890	COG1263	PTS System
KYK33_14890	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KYK33_14910	COG0564	pseudouridine synthase activity
KYK33_14915	COG3098	single-species biofilm formation
KYK33_14940	COG5595	Zn-ribbon-containing, possibly nucleic-acid-binding protein (DUF2310)
KYK33_14950	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
KYK33_14950	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
KYK33_14965	COG1611	Belongs to the LOG family
KYK33_14970	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
KYK33_14975	COG0473	3-isopropylmalate dehydrogenase activity
KYK33_14985	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
KYK33_14990	COG2363	Small membrane protein
KYK33_15000	COG0583	DNA-binding transcription factor activity
KYK33_15005	COG0840	transmembrane signaling receptor activity
KYK33_15010	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
KYK33_15020	COG2991	Protein conserved in bacteria
KYK33_15025	COG1477	protein flavinylation
KYK33_15035	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
KYK33_15040	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
KYK33_15045	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
KYK33_15050	COG1805	sodium ion transport
KYK33_15055	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
KYK33_15060	COG0271	Belongs to the BolA IbaG family
KYK33_15065	COG2813	Specifically methylates the guanine in position
KYK33_15075	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
KYK33_15085	COG2211	Major facilitator Superfamily
KYK33_15095	COG1666	GTP binding
KYK33_15105	COG0693	protein deglycase activity
KYK33_15110	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
KYK33_15115	COG0739	heme binding
KYK33_15120	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
KYK33_15140	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
KYK33_15150	COG3091	SprT-like family
KYK33_15160	COG1385	rRNA (uridine-N3-)-methyltransferase activity
KYK33_15165	COG0189	ligase activity
KYK33_15170	COG1678	Uncharacterized ACR, COG1678
KYK33_15175	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
KYK33_15195	COG1115	amino acid carrier protein
KYK33_15200	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
KYK33_15215	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
KYK33_15230	COG2912	Transglutaminase-like superfamily
KYK33_15240	COG2890	protein-(glutamine-N5) methyltransferase activity
KYK33_15245	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
KYK33_15250	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
KYK33_15255	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
KYK33_15260	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
KYK33_15270	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
KYK33_15275	COG0193	aminoacyl-tRNA hydrolase activity
KYK33_15280	COG0012	GTP binding
KYK33_15325	COG0471	metal ion transport
KYK33_15325	COG0490	domain, Protein
KYK33_15335	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
KYK33_15350	COG1012	belongs to the aldehyde dehydrogenase family
KYK33_15360	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
KYK33_15365	COG0512	Glutamine amidotransferase of anthranilate synthase
KYK33_15375	COG1028	Short-chain dehydrogenase reductase Sdr
KYK33_15385	COG1414	Transcriptional regulator
KYK33_15390	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KYK33_15395	COG0800	Aldolase
KYK33_15400	COG2731	YhcH YjgK YiaL family protein
KYK33_15425	COG0180	Tryptophanyl-tRNA synthetase
KYK33_15435	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
KYK33_15445	COG0338	D12 class N6 adenine-specific DNA methyltransferase
KYK33_15455	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
KYK33_15460	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
KYK33_15490	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
KYK33_15495	COG0583	DNA-binding transcription factor activity
KYK33_15510	COG0583	DNA-binding transcription factor activity
KYK33_15525	COG3121	Chaperone
KYK33_15530	COG3188	usher protein
KYK33_15535	COG3121	Chaperone
KYK33_15545	COG0739	heme binding
KYK33_15555	COG3264	Mechanosensitive ion channel
KYK33_15555	COG1511	domain protein
KYK33_15560	COG0584	glycerophosphoryl diester phosphodiesterase
KYK33_15575	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
KYK33_15595	COG3214	Protein conserved in bacteria
KYK33_15640	COG4067	protein conserved in archaea
KYK33_15640	COG0189	ligase activity
KYK33_15645	COG0516	GMP reductase activity
KYK33_15655	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
KYK33_15665	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KYK33_15670	COG0584	glycerophosphoryl diester phosphodiesterase
KYK33_15685	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
KYK33_15695	COG0583	DNA-binding transcription factor activity
KYK33_15705	COG1335	isochorismatase
KYK33_15710	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
KYK33_15715	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
KYK33_15720	COG1702	phosphate starvation-inducible protein PhoH
KYK33_15725	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
KYK33_15730	COG4535	Mg2 and Co2 transporter CorC
KYK33_15735	COG0815	Transfers the fatty acyl group on membrane lipoproteins
KYK33_15740	COG2888	peptidyl-tyrosine sulfation
KYK33_15745	COG0495	leucyl-tRNA aminoacylation
KYK33_15770	COG1466	dna polymerase III delta subunit
KYK33_15775	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
KYK33_15780	COG0799	negative regulation of ribosome biogenesis
KYK33_15785	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
KYK33_15790	COG0768	penicillin binding
KYK33_15795	COG0772	Belongs to the SEDS family
KYK33_15800	COG2951	lytic endotransglycosylase activity
KYK33_15805	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
KYK33_15810	COG1686	Belongs to the peptidase S11 family
KYK33_15815	COG2921	Belongs to the UPF0250 family
KYK33_15820	COG0321	lipoyl(octanoyl) transferase activity
KYK33_15825	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
KYK33_15835	COG3545	Serine hydrolase
KYK33_15840	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
KYK33_15845	COG1970	mechanosensitive ion channel activity
KYK33_15855	COG4974	Belongs to the 'phage' integrase family
KYK33_15860	COG0716	FMN binding
KYK33_15865	COG0312	modulator of DNA gyrase
KYK33_15870	COG0312	modulator of DNA gyrase
KYK33_15880	COG1376	ErfK ybiS ycfS ynhG family protein
KYK33_15925	COG1566	PFAM secretion protein HlyD family protein
KYK33_15935	COG0114	fumarate hydratase activity
KYK33_15945	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
KYK33_15945	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
KYK33_15945	COG0506	proline dehydrogenase activity
KYK33_15950	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
KYK33_15955	COG0305	Participates in initiation and elongation during chromosome replication
KYK33_15970	COG2200	EAL domain
KYK33_15985	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
KYK33_15995	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
KYK33_16000	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
KYK33_16005	COG0175	sulfate reduction
KYK33_16015	COG2113	Glycine betaine
KYK33_16020	COG4176	ABC-type proline glycine betaine transport system permease component
KYK33_16025	COG4175	Glycine betaine
KYK33_16030	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KYK33_16035	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
KYK33_16040	COG0318	PFAM AMP-dependent synthetase and ligase
KYK33_16045	COG3314	Sporulation integral membrane protein YlbJ
KYK33_16050	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
KYK33_16055	COG0211	Belongs to the bacterial ribosomal protein bL27 family
KYK33_16060	COG0261	This protein binds to 23S rRNA in the presence of protein L20
KYK33_16065	COG0142	geranyltranstransferase activity
KYK33_16070	COG0330	HflC and HflK could
KYK33_16075	COG0330	HflC and HflK could
KYK33_16080	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
KYK33_16085	COG1923	regulation of RNA biosynthetic process
KYK33_16090	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
KYK33_16095	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
KYK33_16105	COG0802	atpase or kinase
KYK33_16110	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
KYK33_16110	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
KYK33_16115	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
KYK33_16125	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
KYK33_16165	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
KYK33_16170	COG1162	GTPase activity
KYK33_16175	COG0688	phosphatidylethanolamine metabolic process
KYK33_16180	COG4628	conserved protein (DUF2132)
KYK33_16195	COG3300	MHYT domain
KYK33_16195	COG5001	Diguanylate cyclase
KYK33_16200	COG3076	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome
KYK33_16225	COG1132	(ABC) transporter
KYK33_16260	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
KYK33_16265	COG2897	thiosulfate sulfurtransferase activity
KYK33_16270	COG2066	Belongs to the glutaminase family
KYK33_16275	COG3171	Protein conserved in bacteria
KYK33_16280	COG0220	tRNA (guanine-N7-)-methyltransferase activity
KYK33_16290	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KYK33_16295	COG2200	EAL domain
KYK33_16300	COG0440	acetolactate synthase activity
KYK33_16305	COG0028	Belongs to the TPP enzyme family
KYK33_16330	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
KYK33_16335	COG0473	3-isopropylmalate dehydrogenase activity
KYK33_16340	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
KYK33_16345	COG0066	3-isopropylmalate dehydratase activity
KYK33_16360	COG4143	(ABC) transporter
KYK33_16365	COG1178	ABC-type Fe3 transport system permease component
KYK33_16370	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
KYK33_16375	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
KYK33_16405	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
KYK33_16410	COG0564	pseudouridine synthase activity
KYK33_16430	COG0459	protein refolding
KYK33_16435	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
KYK33_16440	COG0534	Mate efflux family protein
KYK33_16450	COG1027	Aspartate ammonia-lyase
KYK33_16455	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
KYK33_16460	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
KYK33_16465	COG0477	Major facilitator Superfamily
KYK33_16480	COG3227	Zinc metalloprotease (Elastase)
KYK33_16485	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KYK33_16505	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
KYK33_16510	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
KYK33_16515	COG0635	Involved in the biosynthesis of porphyrin-containing compound
KYK33_16520	COG3036	rescue of stalled ribosome
KYK33_16530	COG0138	bifunctional purine biosynthesis protein purh
KYK33_16535	COG0151	Belongs to the GarS family
KYK33_16540	COG0477	Major facilitator Superfamily
KYK33_16575	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
KYK33_16585	COG1610	YqeY-like protein
KYK33_16590	COG0828	Belongs to the bacterial ribosomal protein bS21 family
KYK33_16595	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
KYK33_16610	COG1238	metal cluster binding
KYK33_16615	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
KYK33_16620	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
KYK33_16625	COG0585	pseudouridine synthase activity
KYK33_16635	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
KYK33_16640	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
KYK33_16645	COG0148	phosphopyruvate hydratase activity
KYK33_16650	COG0504	CTP synthase activity
KYK33_16655	COG3956	TIGRFAM MazG family protein
KYK33_16660	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
KYK33_16665	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
KYK33_16675	COG4807	Protein conserved in bacteria
KYK33_16680	COG3023	N-Acetylmuramoyl-L-alanine amidase
KYK33_16685	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
KYK33_16690	COG1381	Involved in DNA repair and RecF pathway recombination
KYK33_16700	COG0571	ribonuclease III activity
KYK33_16710	COG0481	GTPase activity
KYK33_16720	COG3026	antisigma factor binding
KYK33_16725	COG3073	An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E
KYK33_16730	COG1595	DNA-templated transcription, initiation
KYK33_16735	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
KYK33_16745	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
KYK33_16755	COG4178	(ABC) transporter
KYK33_16760	COG0583	DNA-binding transcription factor activity
KYK33_16775	COG1324	tolerance protein
KYK33_16800	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KYK33_16805	COG0191	fructose-bisphosphate aldolase activity
KYK33_16810	COG0126	phosphoglycerate kinase activity
KYK33_16815	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
KYK33_16820	COG1940	carbohydrate kinase activity
KYK33_16825	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
KYK33_16830	COG2816	NAD+ diphosphatase activity
KYK33_16835	COG4991	sh3 domain protein
KYK33_16840	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
KYK33_16855	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
KYK33_16885	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
KYK33_16885	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
KYK33_16915	COG2070	2-Nitropropane dioxygenase
KYK33_16950	COG0513	Belongs to the DEAD box helicase family
KYK33_16965	COG2801	Transposase and inactivated derivatives
KYK33_16965	COG3415	Transposase
KYK33_16970	COG0154	amidase activity
KYK33_16975	COG2957	Belongs to the agmatine deiminase family
KYK33_16985	COG2852	Protein conserved in bacteria
KYK33_16995	COG1902	pentaerythritol trinitrate reductase activity
KYK33_17025	COG5001	Diguanylate cyclase
KYK33_17040	COG2425	protein containing a von Willebrand factor type A (vWA) domain
KYK33_17045	COG0714	Associated with various cellular activities
KYK33_17055	COG0456	acetyltransferase
KYK33_17065	COG1022	Amp-dependent synthetase and ligase
KYK33_17080	COG2918	glutathione biosynthetic process
KYK33_17085	COG0612	Peptidase, M16
KYK33_17090	COG1238	metal cluster binding
KYK33_17095	COG0604	alcohol dehydrogenase
KYK33_17095	COG1028	Short-chain dehydrogenase reductase Sdr
KYK33_17095	COG3321	synthase
KYK33_17115	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
KYK33_17120	COG0359	binds to the 23S rRNA
KYK33_17125	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
KYK33_17130	COG0360	Binds together with S18 to 16S ribosomal RNA
KYK33_17135	COG1914	H( )-stimulated, divalent metal cation uptake system
KYK33_17155	COG2153	protein acetylation
KYK33_17165	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KYK33_17170	COG0557	exoribonuclease II activity
KYK33_17175	COG3706	GGDEF domain
KYK33_17180	COG1854	S-ribosylhomocysteine lyase activity
KYK33_17195	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
KYK33_17195	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
KYK33_17235	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
KYK33_17240	COG1047	Peptidyl-prolyl cis-trans
KYK33_17245	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
KYK33_17250	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
KYK33_17255	COG0196	riboflavin kinase activity
KYK33_17260	COG0728	peptidoglycan biosynthetic process
KYK33_17265	COG0268	Binds directly to 16S ribosomal RNA
KYK33_17270	COG0640	Transcriptional regulator
KYK33_17275	COG0583	DNA-binding transcription factor activity
KYK33_17285	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
KYK33_17290	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
KYK33_17295	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
KYK33_17305	COG1051	belongs to the nudix hydrolase family
KYK33_17310	COG3066	DNA modification
KYK33_17320	COG0335	large ribosomal subunit rRNA binding
KYK33_17325	COG0336	Belongs to the RNA methyltransferase TrmD family
KYK33_17330	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
KYK33_17335	COG0228	four-way junction DNA binding
KYK33_17340	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
KYK33_17345	COG4137	Cytochrome C assembly protein
KYK33_17350	COG4536	flavin adenine dinucleotide binding
KYK33_17360	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
KYK33_17360	COG1017	nitric oxide dioxygenase activity
KYK33_17365	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
KYK33_17370	COG0039	L-malate dehydrogenase activity
KYK33_17375	COG4160	amino acid transport
KYK33_17380	COG4215	(ABC) transporter
KYK33_17385	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KYK33_17390	COG1126	abc transporter atp-binding protein
KYK33_17395	COG1438	arginine binding
KYK33_17400	COG2837	iron assimilation
KYK33_17415	COG1840	ABC-type Fe3 transport system, periplasmic component
KYK33_17420	COG0004	ammonium transporteR
KYK33_17425	COG0347	Belongs to the P(II) protein family
KYK33_17435	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
KYK33_17455	COG1929	Belongs to the glycerate kinase type-1 family
KYK33_17460	COG2610	gluconate transmembrane transporter activity
KYK33_17465	COG3835	regulator
KYK33_17470	COG3112	Uncharacterised protein family (UPF0231)
KYK33_17500	COG0513	Belongs to the DEAD box helicase family
KYK33_17535	COG1448	Aminotransferase
KYK33_17550	COG0628	permease
KYK33_17555	COG1538	Outer membrane efflux protein
KYK33_17600	COG4783	chaperone-mediated protein folding
KYK33_17605	COG1215	transferase activity, transferring glycosyl groups
KYK33_17610	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
KYK33_17620	COG3397	chitin binding
KYK33_17625	COG0583	DNA-binding transcription factor activity
KYK33_17630	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
KYK33_17635	COG4208	sulfate ABC transporter
KYK33_17640	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
KYK33_17650	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
KYK33_17655	COG3174	membrane
KYK33_17660	COG0110	maltose O-acetyltransferase activity
KYK33_17670	COG1263	PTS System
KYK33_17670	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KYK33_17675	COG1653	transport
KYK33_17705	COG0165	Argininosuccinate lyase
KYK33_17710	COG0137	argininosuccinate synthase activity
KYK33_17720	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
KYK33_17725	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
KYK33_17735	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
KYK33_17740	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
KYK33_17765	COG0583	DNA-binding transcription factor activity
KYK33_17770	COG1380	Effector of murein hydrolase LrgA
KYK33_17775	COG1346	cytolysis
KYK33_17780	COG0527	aspartate kinase activity
KYK33_17780	COG0460	homoserine dehydrogenase
KYK33_17785	COG0626	cystathionine gamma-synthase activity
KYK33_17810	COG1218	3'(2'),5'-bisphosphate nucleotidase
KYK33_17815	COG0494	nUDIX hydrolase
KYK33_17820	COG1011	Hydrolase
KYK33_17825	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
KYK33_17840	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
KYK33_17850	COG3156	type II secretion system protein K
KYK33_17855	COG4795	General secretion pathway protein
KYK33_17860	COG2165	general secretion pathway protein
KYK33_17870	COG2165	general secretion pathway protein
KYK33_17875	COG1459	type II secretion system
KYK33_17880	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
KYK33_17890	COG3031	protein transport across the cell outer membrane
KYK33_17900	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
KYK33_17905	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
KYK33_17920	COG0456	acetyltransferase
KYK33_17925	COG3133	Outer membrane lipoprotein
KYK33_17940	COG2771	luxR family
KYK33_17955	COG4776	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction
KYK33_17960	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
KYK33_17960	COG2213	PTS system mannitol-specific
KYK33_17965	COG0246	Mannitol dehydrogenase
KYK33_17970	COG3722	fumarate hydratase activity
KYK33_17995	COG1671	Belongs to the UPF0178 family
KYK33_18000	COG1988	membrane-bound metal-dependent
KYK33_18005	COG4932	domain protein
KYK33_18005	COG5492	domain, Protein
KYK33_18010	COG0513	Belongs to the DEAD box helicase family
KYK33_18025	COG1368	sulfuric ester hydrolase activity
KYK33_18030	COG1522	sequence-specific DNA binding
KYK33_18050	COG2321	neutral zinc metallopeptidase
KYK33_18060	COG0477	Major facilitator Superfamily
KYK33_18070	COG0312	modulator of DNA gyrase
KYK33_18075	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
KYK33_18080	COG3164	Protein of unknown function
KYK33_18085	COG1530	ribonuclease E activity
KYK33_18090	COG0424	maF-like protein
KYK33_18095	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
KYK33_18100	COG1792	Involved in formation and maintenance of cell shape
KYK33_18105	COG1077	Cell shape determining protein MreB Mrl
KYK33_18130	COG4969	Belongs to the N-Me-Phe pilin family
KYK33_18135	COG2165	general secretion pathway protein
KYK33_18140	COG2165	general secretion pathway protein
KYK33_18150	COG1459	type II secretion system
KYK33_18155	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
KYK33_18205	COG2200	EAL domain
KYK33_18225	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
KYK33_18230	COG1074	ATP-dependent DNA helicase activity
KYK33_18235	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
KYK33_18245	COG2259	Doxx family
KYK33_18250	COG1741	Belongs to the pirin family
KYK33_18260	COG0583	DNA-binding transcription factor activity
KYK33_18285	COG1175	transmembrane transport
KYK33_18295	COG3842	ATPase activity
KYK33_18305	COG0840	transmembrane signaling receptor activity
KYK33_18325	COG2207	Transcriptional regulator
KYK33_18330	COG1247	-acetyltransferase
KYK33_18335	COG0753	catalase activity
KYK33_18365	COG0628	permease
KYK33_18380	COG2957	Belongs to the agmatine deiminase family
KYK33_18390	COG2957	Belongs to the agmatine deiminase family
KYK33_18395	COG0583	DNA-binding transcription factor activity
KYK33_18400	COG3284	Transcriptional regulator
KYK33_18405	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
KYK33_18405	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
KYK33_18405	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
KYK33_18410	COG1461	Dihydroxyacetone kinase
KYK33_18415	COG2376	Dihydroxyacetone kinase
KYK33_18420	COG2252	PERMEase
KYK33_18425	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
KYK33_18460	COG0203	ribosomal protein L17
KYK33_18465	COG0202	RNA polymerase activity
KYK33_18470	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
KYK33_18475	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
KYK33_18480	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
KYK33_18485	COG0257	Belongs to the bacterial ribosomal protein bL36 family
KYK33_18490	COG0201	protein transport
KYK33_18495	COG0200	Binds to the 23S rRNA
KYK33_18500	COG1841	ribosomal large subunit assembly
KYK33_18505	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
KYK33_18510	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
KYK33_18515	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
KYK33_18520	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
KYK33_18525	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
KYK33_18530	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
KYK33_18535	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
KYK33_18540	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
KYK33_18545	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
KYK33_18550	COG0255	Belongs to the universal ribosomal protein uL29 family
KYK33_18555	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
KYK33_18560	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
KYK33_18565	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
KYK33_18570	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
KYK33_18575	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
KYK33_18580	COG0089	rRNA binding
KYK33_18585	COG0088	Forms part of the polypeptide exit tunnel
KYK33_18590	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
KYK33_18595	COG0051	transcription antitermination factor activity, RNA binding
KYK33_18605	COG2205	protein histidine kinase activity
KYK33_18615	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
KYK33_18620	COG2183	response to ionizing radiation
KYK33_18635	COG0596	Alpha beta hydrolase
KYK33_18640	COG1040	competence protein
KYK33_18645	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
KYK33_18645	COG0316	Belongs to the HesB IscA family
KYK33_18650	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
KYK33_18655	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
KYK33_18660	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KYK33_18665	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
KYK33_18670	COG4942	peptidase
KYK33_18685	COG0800	Aldolase
KYK33_18700	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KYK33_18705	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
KYK33_18715	COG0456	acetyltransferase
KYK33_18725	COG1490	D-aminoacyl-tRNA deacylase activity
KYK33_18730	COG1295	ribonuclease BN
KYK33_18735	COG1217	gtp-binding protein TYPA
KYK33_18740	COG0174	glutamine synthetase
KYK33_18750	COG3852	Histidine kinase
KYK33_18755	COG2204	response regulator
KYK33_18765	COG3258	Cytochrome c
KYK33_18770	COG2863	cytochrome
KYK33_18775	COG0542	response to heat
KYK33_18785	COG0564	pseudouridine synthase activity
KYK33_18790	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
KYK33_18795	COG3681	Belongs to the UPF0597 family
KYK33_18800	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
KYK33_18805	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
KYK33_18810	COG1979	alcohol dehydrogenase
KYK33_18815	COG2207	Transcriptional regulator
KYK33_18820	COG3040	lipid binding
KYK33_18825	COG0840	transmembrane signaling receptor activity
KYK33_18840	COG0540	Belongs to the ATCase OTCase family
KYK33_18845	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
KYK33_18850	COG1438	arginine binding
KYK33_18855	COG1288	antiporter activity
KYK33_18860	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
KYK33_18905	COG3250	beta-galactosidase activity
KYK33_18910	COG1609	Transcriptional regulator
KYK33_18915	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
KYK33_18925	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
KYK33_18930	COG2017	converts alpha-aldose to the beta-anomer
KYK33_18935	COG0667	Aldo Keto reductase
KYK33_18940	COG1968	undecaprenyl-diphosphatase activity
KYK33_18950	COG1595	DNA-templated transcription, initiation
KYK33_18960	COG0018	arginyl-trna synthetase
KYK33_18970	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
KYK33_18975	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
KYK33_18990	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
KYK33_19000	COG2116	formate transmembrane transporter activity
KYK33_19005	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
KYK33_19005	COG1648	precorrin-2 dehydrogenase activity
KYK33_19010	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
KYK33_19020	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
KYK33_19030	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
KYK33_19040	COG0514	ATP-dependent DNA helicase (RecQ)
KYK33_19045	COG2050	protein possibly involved in aromatic compounds catabolism
KYK33_19060	COG2258	MOSC domain
KYK33_19065	COG1177	transmembrane transport
KYK33_19070	COG1176	ABC-type spermidine putrescine transport system, permease component I
KYK33_19075	COG3842	ATPase activity
KYK33_19095	COG0174	glutamine synthetase
KYK33_19110	COG3045	CreA protein
KYK33_19115	COG4221	oxidoreductase activity
KYK33_19120	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KYK33_19125	COG0443	Heat shock 70 kDa protein
KYK33_19140	COG0366	Alpha amylase catalytic
KYK33_19155	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
KYK33_19160	COG0745	RESPONSE REGULATOR receiver
KYK33_19165	COG2205	protein histidine kinase activity
KYK33_19175	COG0281	malic enzyme
KYK33_19180	COG0702	epimerase
KYK33_19185	COG0254	rRNA binding
KYK33_19190	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
KYK33_19200	COG0385	Bile acid
KYK33_19235	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
KYK33_19240	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
KYK33_19240	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
KYK33_19245	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
KYK33_19250	COG3074	FtsZ-dependent cytokinesis
KYK33_19260	COG1045	serine acetyltransferase
KYK33_19270	COG0745	RESPONSE REGULATOR receiver
KYK33_19275	COG2205	protein histidine kinase activity
KYK33_19280	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
KYK33_19285	COG0534	Mate efflux family protein
KYK33_19295	COG0109	protoheme IX farnesyltransferase activity
KYK33_19300	COG1612	heme a metabolic process
KYK33_19330	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
KYK33_19335	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
KYK33_19340	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
KYK33_19345	COG2937	Belongs to the GPAT DAPAT family
KYK33_19350	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
KYK33_19355	COG3161	chorismate lyase activity
KYK33_19360	COG1580	Controls the rotational direction of flagella during chemotaxis
KYK33_19375	COG1519	Transferase
KYK33_19380	COG0859	PFAM glycosyl transferase family 9
KYK33_19390	COG0438	transferase activity, transferring glycosyl groups
KYK33_19400	COG0438	transferase activity, transferring glycosyl groups
KYK33_19410	COG0859	PFAM glycosyl transferase family 9
KYK33_19415	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
KYK33_19420	COG2990	Protein conserved in bacteria
KYK33_19425	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
KYK33_19435	COG0267	Belongs to the bacterial ribosomal protein bL33 family
KYK33_19440	COG0227	Belongs to the bacterial ribosomal protein bL28 family
KYK33_19445	COG2003	Belongs to the UPF0758 family
KYK33_19450	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
KYK33_19455	COG0756	dUTP diphosphatase activity
KYK33_19460	COG1309	transcriptional regulator
KYK33_19465	COG0668	transmembrane transport
KYK33_19470	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
KYK33_19475	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
KYK33_19480	COG1561	YicC-like family, N-terminal region
KYK33_19510	COG1479	Protein of unknown function DUF262
KYK33_19520	COG0732	type I restriction modification DNA specificity domain
KYK33_19545	COG3550	peptidyl-serine autophosphorylation
KYK33_19610	COG0438	transferase activity, transferring glycosyl groups
KYK33_19615	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
KYK33_19630	COG1063	alcohol dehydrogenase
KYK33_19640	COG5001	Diguanylate cyclase
KYK33_19640	COG3300	MHYT domain
KYK33_19650	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
KYK33_19655	COG2166	iron-sulfur cluster assembly
KYK33_19660	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
KYK33_19665	COG1119	ATPase activity
KYK33_19700	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
KYK33_19705	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
KYK33_19710	COG1739	Uncharacterized protein family UPF0029
KYK33_19715	COG0006	proline dipeptidase activity
KYK33_19720	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
KYK33_19725	COG1024	Enoyl-CoA hydratase
KYK33_19725	COG1250	3-hydroxyacyl-CoA dehydrogenase
KYK33_19730	COG0183	Belongs to the thiolase family
KYK33_19755	COG0425	Belongs to the sulfur carrier protein TusA family
KYK33_19760	COG0251	oxidation-reduction process
KYK33_19765	COG2885	chlorophyll binding
KYK33_19780	COG2818	Glycosylase
KYK33_19785	COG0752	glycyl-tRNA synthetase alpha subunit
KYK33_19790	COG0751	glycine-tRNA ligase activity
KYK33_19805	COG0814	amino acid
KYK33_19810	COG0348	domain, Protein
KYK33_19820	COG0446	pyridine nucleotide-disulphide oxidoreductase
KYK33_19825	COG0426	domain, Protein
KYK33_19825	COG1773	rubredoxin
KYK33_19830	COG3604	Transcriptional regulator
KYK33_19840	COG0084	hydrolase, TatD family'
KYK33_19845	COG0805	protein transport
KYK33_19850	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
KYK33_19860	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
KYK33_19875	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
KYK33_19880	COG0402	S-adenosylhomocysteine deaminase activity
KYK33_19920	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
KYK33_19925	COG0848	biopolymer transport protein
KYK33_19930	COG0811	peptide transport
KYK33_19935	COG0811	peptide transport
KYK33_19945	COG2771	luxR family
KYK33_19950	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
KYK33_19955	COG1349	DNA-binding transcription factor activity
KYK33_19960	COG0745	RESPONSE REGULATOR receiver
KYK33_19965	COG2205	protein histidine kinase activity
KYK33_19970	COG4452	Inner membrane protein CreD
KYK33_19975	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
KYK33_19980	COG0355	proton-transporting ATP synthase activity, rotational mechanism
KYK33_19985	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
KYK33_19990	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
KYK33_19995	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
KYK33_20000	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
KYK33_20005	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
KYK33_20015	COG0356	it plays a direct role in the translocation of protons across the membrane
KYK33_20025	COG1475	DNA binding
KYK33_20030	COG1192	Involved in chromosome partitioning
KYK33_20035	COG0357	Ribosomal RNA small subunit methyltransferase G
KYK33_20040	COG0445	tRNA wobble uridine modification
KYK33_20045	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
KYK33_20050	COG4774	siderophore transport
KYK33_20055	COG4615	Cyclic peptide transporter
KYK33_20060	COG1120	ATPase activity
KYK33_20065	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
KYK33_20070	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KYK33_20075	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
KYK33_20080	COG0706	membrane insertase activity
KYK33_20085	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
KYK33_20090	COG0594	ribonuclease P activity
KYK33_20095	COG0230	Belongs to the bacterial ribosomal protein bL34 family
KYK33_20100	COG1126	abc transporter atp-binding protein