locus-tag	class	description
O23A_P3p0004	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
O23A_P3p0022	ENOG4107QHF	type ii secretion system protein e
O23A_P3p0046	ENOG4105VJY	transcriptional regulator
O23A_P3p0062	ENOG4107QJE	Chromosome Partitioning Protein
O23A_P4p0008	ENOG4105W5Q	DNA repair protein (RadC
O23A_P4p0017	ENOG4105PF0	Antitoxin component of a toxin-antitoxin (TA) module. Functions as an mRNA interferase antitoxin
O23A_P4p0018	ENOG41063XI	Toxic component of a toxin-antitoxin (TA) module. A
O23A_P4p0026	ENOG4105KT5	UmuD protein
O23A_P4p0027	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
O23A_P4p0043	ENOG4107QJE	Chromosome Partitioning Protein
O23A_p0001	ENOG4107R88	Chemotaxis protein (CheV)
O23A_p0002	ENOG4108UJV	acyl-CoA thioesterase i
O23A_p0003	ENOG4108I0Y	(ABC) transporter
O23A_p0004	ENOG4105CV6	ABC transporter, permease
O23A_p0005	ENOG4105ECP	epimerase
O23A_p0006	ENOG4105BZU	Histidine kinase
O23A_p0007	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
O23A_p0009	ENOG4105IIU	Aminopeptidase
O23A_p0010	ENOG4105CZ1	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity)
O23A_p0011	ENOG41090ED	Protein with unknown function (DUF469)
O23A_p0012	ENOG4105CSV	Glutaminase
O23A_p0013	ENOG4107RM6	sulfurtransferase
O23A_p0014	ENOG4105SUV	lipoprotein YgdR
O23A_p0015	ENOG4105BZ1	(ABC) transporter
O23A_p0019	ENOG4105C26	Dehydrogenase
O23A_p0020	ENOG4105CZ6	Can catalyze the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine (By similarity)
O23A_p0023	ENOG4107G87	m6 family metalloprotease domain protein
O23A_p0025	ENOG4105KQT	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome (By similarity)
O23A_p0026	ENOG4105BZU	Histidine kinase
O23A_p0030	ENOG4105VYA	Uncharacterized conserved protein (DUF2132)
O23A_p0031	ENOG4105DJ4	phosphatidylserine decarboxylase
O23A_p0032	ENOG4105E06	May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity)
O23A_p0033	ENOG4108RBP	3'-to-5' exoribonuclease specific for small oligoribonucleotides (By similarity)
O23A_p0034	ENOG4105VEQ	Cold shock protein
O23A_p0036	ENOG4105C8Q	Methyl-accepting chemotaxis
O23A_p0037	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
O23A_p0038	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
O23A_p0043	ENOG4109015	Biopolymer transport protein exbD tolR
O23A_p0048	ENOG4108I5X	binding-protein-dependent transport systems inner membrane Component
O23A_p0049	ENOG4108IYQ	Binding-protein-dependent transport systems inner membrane component
O23A_p0050	ENOG4107QRA	Extracellular solute-binding protein, family 5
O23A_p0052	ENOG4108JQ7	(ABC) transporter
O23A_p0054	ENOG4105CIN	aminoacyl-histidine dipeptidase
O23A_p0057	ENOG4105DYA	Acts on guanine, xanthine and to a lesser extent hypoxanthine (By similarity)
O23A_p0058	ENOG4105V1F	Fermentation respiration switch protein
O23A_p0060	ENOG4105CGT	Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity)
O23A_p0061	ENOG4105C2S	Catalyzes the NADPH dependent reduction of L-gamma- glutamyl 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate (By similarity)
O23A_p0068	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
O23A_p0071	ENOG4105DG7	nitrate ABC transporter
O23A_p0072	ENOG4105D7T	ABC transporter
O23A_p0073	ENOG4107QZF	nitrite reductase NADPH large subunit
O23A_p0074	ENOG4107QZF	nitrite reductase NADPH large subunit
O23A_p0076	ENOG4105DD7	kinase (PfkB family
O23A_p0077	ENOG4105D53	Catalyzes the hydrolysis of pseudouridine 5'-phosphate (PsiMP) to ribose 5-phosphate and uracil (By similarity)
O23A_p0080	ENOG4105CA0	peroxidase
O23A_p0087	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
O23A_p0090	ENOG4108KW7	amp-dependent synthetase and ligase
O23A_p0093	ENOG4105C84	Histidine ammonia-lyase
O23A_p0099	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
O23A_p0101	ENOG4105C2D	reductase
O23A_p0102	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
O23A_p0104	ENOG4108RIR	Molybdenum cofactor biosynthesis protein
O23A_p0106	ENOG4105DWK	Membrane
O23A_p0108	ENOG4107XM3	UPF0442 protein
O23A_p0110	ENOG4108IJ7	Glycine betaine
O23A_p0111	ENOG4108HQS	Glycine betaine
O23A_p0112	ENOG4105GIJ	Glycine betaine
O23A_p0113	ENOG4105ET3	Reduction of activated sulfate into sulfite (By similarity)
O23A_p0114	ENOG4105ET1	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate (By similarity)
O23A_p0115	ENOG4107EER	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity)
O23A_p0116	ENOG4107TIF	Phenazine biosynthesis protein, PhzF family
O23A_p0117	ENOG4105CRK	lysyL-tRNA synthetase
O23A_p0118	ENOG4105CG1	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA (By similarity)
O23A_p0119	ENOG4105C8Q	Methyl-accepting chemotaxis
O23A_p0120	ENOG4105D6U	Sodium Glutamate Symporter
O23A_p0121	ENOG4105HDK	L-asparaginase
O23A_p0122	ENOG4105VUT	cytoplasmic protein
O23A_p0126	ENOG4105D07	Signal peptide peptidase, SppA
O23A_p0127	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
O23A_p0128	ENOG41069NU	Nitroreductase
O23A_p0129	ENOG4108UW5	maltose o-acetyltransferase
O23A_p0130	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
O23A_p0132	ENOG4105CIS	alcohol dehydrogenase
O23A_p0133	ENOG4105HEI	LysR family (Transcriptional regulator
O23A_p0134	ENOG4105CI1	PTS System
O23A_p0135	ENOG4108IA2	Sodium pantothenate symporter
O23A_p0136	ENOG4105RG0	Membrane
O23A_p0137	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
O23A_p0138	ENOG4105KM4	Acetyl-CoA carboxylase, biotin carboxyl carrier protein
O23A_p0139	ENOG4108Z38	Catalyzes a trans-dehydration via an enolate intermediate (By similarity)
O23A_p0140	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
O23A_p0142	ENOG4105BZU	Histidine kinase
O23A_p0146	ENOG4109039	Involved in the biogenesis of TorA. Acts on TorA before the insertion of the molybdenum cofactor and, as a result, probably favors a conformation of the apoenzyme that is competent for acquiring the cofactor (By similarity)
O23A_p0150	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
O23A_p0153	ENOG4108Z11	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes (By similarity)
O23A_p0154	ENOG4105D1W	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity)
O23A_p0157	ENOG4108UTT	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity)
O23A_p0158	ENOG4107YIM	Involved in the transcription termination process (By similarity)
O23A_p0159	ENOG4105CG2	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity)
O23A_p0160	ENOG4108ZAI	phosphatidylglycerophosphatase a
O23A_p0161	ENOG4108JQ6	ABC transporter
O23A_p0163	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
O23A_p0165	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
O23A_p0166	ENOG4105CTB	Polyprenyl synthetase
O23A_p0167	ENOG41067QG	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
O23A_p0168	ENOG4105E14	MotA TolQ exbB proton channel
O23A_p0169	ENOG4107XSU	flagellar motor protein motb
O23A_p0173	ENOG4108UKH	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
O23A_p0175	ENOG4105HBR	Rna-binding protein
O23A_p0176	ENOG4105F7M	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit (By similarity)
O23A_p0177	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
O23A_p0178	ENOG4105EEI	dihydropteroate synthase
O23A_p0179	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
O23A_p0180	ENOG4105CP7	Triose-phosphate isomerase
O23A_p0182	ENOG4105K7D	Required for maturation of 30S ribosomal subunits (By similarity)
O23A_p0183	ENOG4105CHV	Transcription elongation factor NusA
O23A_p0184	ENOG4107QHU	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
O23A_p0185	ENOG4105KG7	Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity)
O23A_p0186	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
O23A_p0187	ENOG4105K77	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity)
O23A_p0188	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
O23A_p0189	ENOG4105E5W	Transporter
O23A_p0190	ENOG4105BZU	Histidine kinase
O23A_p0191	ENOG41090EX	DsrE family
O23A_p0192	ENOG4105WAY	exported protein
O23A_p0194	ENOG4108WQH	regulatoR
O23A_p0204	ENOG4105EQ6	Hydrolyzes dipeptides containing N-terminal aspartate residues. May play a role in allowing the cell to use peptide aspartate to spare carbon otherwise required for the synthesis of the aspartate family of amino acids (By similarity)
O23A_p0210	ENOG4107N1Q	ErfK YbiS YcfS YnhG family protein
O23A_p0213	ENOG4105D1U	peptidase U62 modulator of DNA gyrase
O23A_p0214	ENOG41071R3	Low-potential electron donor to a number of redox enzymes (By similarity)
O23A_p0215	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
O23A_p0216	ENOG4105M2E	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell (By similarity)
O23A_p0218	ENOG4105C2R	Single-stranded-DNA-specific exonuclease (RecJ)
O23A_p0220	ENOG4108IUB	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
O23A_p0222	ENOG4108HK0	-acetyltransferase
O23A_p0223	ENOG4105C0G	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity)
O23A_p0225	ENOG4108BDP	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity)
O23A_p0226	ENOG4108Z43	UPF0250 protein
O23A_p0227	ENOG4105DZ1	carboxypeptidase
O23A_p0228	ENOG4105K6T	rare lipoprotein A
O23A_p0229	ENOG4105CVE	Lytic murein transglycosylase
O23A_p0230	ENOG4105CNI	cell division protein FtsW
O23A_p0231	ENOG4105CJN	penicillin-binding protein
O23A_p0232	ENOG4108UXA	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA (By similarity)
O23A_p0233	ENOG4105KEM	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation (By similarity)
O23A_p0234	ENOG4108Z1W	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity)
O23A_p0238	ENOG4105C8T	Leucyl-tRNA synthetase
O23A_p0239	ENOG4107PAI	alpha helical protein
O23A_p0240	ENOG4105CE8	Transfers the fatty acyl group on membrane lipoproteins (By similarity)
O23A_p0241	ENOG4108JU5	Magnesium and cobalt efflux protein
O23A_p0242	ENOG4105KGE	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA (By similarity)
O23A_p0243	ENOG4105C9A	Phoh family
O23A_p0244	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
O23A_p0245	ENOG4105EAK	ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family
O23A_p0246	ENOG4105VEQ	Cold shock protein
O23A_p0247	ENOG4105BZU	Histidine kinase
O23A_p0250	ENOG4105EVE	HAD-superfamily hydrolase subfamily IA variant 3
O23A_p0257	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
O23A_p0259	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
O23A_p0261	ENOG4105DHQ	Histidine kinase
O23A_p0262	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
O23A_p0266	ENOG4108IQE	Amp-dependent synthetase and ligase
O23A_p0269	ENOG4105T0Z	Conserved Protein
O23A_p0273	ENOG4108VP9	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane (By similarity)
O23A_p0274	ENOG4108WJH	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane (By similarity)
O23A_p0275	ENOG4105E33	succinate dehydrogenase
O23A_p0279	ENOG4105C8Q	Methyl-accepting chemotaxis
O23A_p0280	ENOG4108QXE	glycerophosphoryl diester phosphodiesterase
O23A_p0281	ENOG4105EGS	Mechanosensitive ion channel
O23A_p0283	ENOG4105DR5	peptidase
O23A_p0286	ENOG4105EJC	lysr family transcriptional regulator
O23A_p0289	ENOG4105C8Q	Methyl-accepting chemotaxis
O23A_p0290	ENOG4105C5Q	Transcriptional regulator
O23A_p0291	ENOG4108JQC	penicillin-binding protein 1A
O23A_p0296	ENOG4105E4G	Type IV pilus
O23A_p0297	ENOG4105KHV	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
O23A_p0298	ENOG4105D49	3-dehydroquinate synthase
O23A_p0300	ENOG4105DFE	Dna adenine methylase
O23A_p0302	ENOG4105DJV	ribulose-phosphate 3-epimerase
O23A_p0303	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
O23A_p0304	ENOG4105C31	Tryptophanyl-tRNA synthetase
O23A_p0306	ENOG4105DDQ	anthranilate synthase
O23A_p0307	ENOG4105C8Y	Acetylornithine aminotransferase
O23A_p0309	ENOG4105C26	Dehydrogenase
O23A_p0311	ENOG4107VXZ	Hydrolase
O23A_p0313	ENOG4105D95	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin (By similarity)
O23A_p0314	ENOG4107QF7	multi-drug
O23A_p0315	ENOG4105C5H	ABC transporter
O23A_p0318	ENOG4105CG3	alpha amylase, catalytic region
O23A_p0320	ENOG4105N5Z	UPF0267 protein
O23A_p0322	ENOG4108I5U	Uridine phosphorylase
O23A_p0323	ENOG4106Z1T	Nicotinamide Mononucleotide Transporter
O23A_p0324	ENOG4107QWE	)-transporter
O23A_p0325	ENOG4105C3G	gtp-binding protein
O23A_p0326	ENOG4108ZPD	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity)
O23A_p0327	ENOG4105CGH	5'-nucleotidase
O23A_p0328	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
O23A_p0329	ENOG4105CTR	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol (By similarity)
O23A_p0330	ENOG4105C1U	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein (By similarity)
O23A_p0331	ENOG4105C7E	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) (By similarity)
O23A_p0332	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
O23A_p0333	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
O23A_p0335	ENOG41063JG	Transcriptional regulator
O23A_p0336	ENOG4105CXR	Phospho-2-dehydro-3-deoxyoctonate aldolase
O23A_p0337	ENOG4105CK2	sodium dicarboxylate symporter
O23A_p0338	ENOG4108VKA	Acts as a radical domain for damaged PFL and possibly other radical proteins (By similarity)
O23A_p0339	ENOG4105D5S	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine (By similarity)
O23A_p0342	ENOG4105CW3	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
O23A_p0343	ENOG4105BZG	amino acid carrier protein
O23A_p0344	ENOG4105F8C	transglutaminase domain-containing protein
O23A_p0346	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
O23A_p0349	ENOG4105G2Y	Transcriptional regulator
O23A_p0350	ENOG4107Y66	Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity)
O23A_p0351	ENOG4108UJU	UPF0301 protein
O23A_p0352	ENOG4108NVR	Methyl-accepting chemotaxis
O23A_p0353	ENOG4105D7Z	glutathione synthase
O23A_p0354	ENOG4105QF0	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity)
O23A_p0356	ENOG4105GPY	SprT protein
O23A_p0357	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
O23A_p0358	ENOG4105CV1	Transketolase (EC 2.2.1.1)
O23A_p0360	ENOG4105KME	endoribonuclease L-psp
O23A_p0362	ENOG4105ED7	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling (By similarity)
O23A_p0363	ENOG4105DR5	peptidase
O23A_p0364	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
O23A_p0370	ENOG4105DIT	ErfK YbiS YcfS YnhG family protein
O23A_p0371	ENOG4105EAQ	(twin-arginine translocation) pathway signal
O23A_p0373	ENOG4105EN6	Membrane
O23A_p0374	ENOG4105EXN	Sulfate transport protein CysZ
O23A_p0375	ENOG4105CDB	Required for chromosome condensation and partitioning (By similarity)
O23A_p0377	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
O23A_p0379	ENOG4105CJD	(Anaerobic) ribonucleoside-triphosphate reductase
O23A_p0380	ENOG4108RDD	Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine (By similarity)
O23A_p0385	ENOG4105J12	Multidrug resistance protein mdtN
O23A_p0386	ENOG4108US0	Transcription regulator that can specifically activate or repress expression of target genes (By similarity)
O23A_p0391	ENOG4107R1I	NAD-dependent malic enzyme
O23A_p0392	ENOG4105CEQ	signal transduction histidine kinase regulating citrate malate metabolism
O23A_p0393	ENOG4106YYS	transcriptional regulatory protein
O23A_p0395	ENOG4105CPC	Aldo Keto reductase
O23A_p0397	ENOG4108IPJ	Membrane
O23A_p0399	ENOG4105C26	Dehydrogenase
O23A_p0400	ENOG4108JU9	GAF modulated sigma54 specific transcriptional regulator Fis family
O23A_p0402	ENOG4105BZU	Histidine kinase
O23A_p0403	ENOG4108ZI4	Glyoxalase Bleomycin resistance protein (Dioxygenase
O23A_p0404	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
O23A_p0405	ENOG4105BZU	Histidine kinase
O23A_p0407	ENOG4105ERG	peptidase m48, ste24p
O23A_p0409	ENOG4105EZX	Catalyzes the phosphorylation of N-acetyl-D-glucosamine (GlcNAc) derived from cell-wall degradation, yielding GlcNAc-6-P (By similarity)
O23A_p0410	ENOG4106N3A	copper homeostasis protein cutc
O23A_p0411	ENOG4108V1T	peptidylprolyl cis-trans isomerase
O23A_p0412	ENOG4105CJ1	ABC, transporter
O23A_p0416	ENOG4105PTV	Nudix Hydrolase
O23A_p0422	ENOG4105BZG	amino acid carrier protein
O23A_p0423	ENOG4108KMH	lipoate-protein ligase a
O23A_p0424	ENOG4105C2W	permease
O23A_p0425	ENOG4105BZU	Histidine kinase
O23A_p0426	ENOG4105RKX	Protein of unknown function (DUF2498)
O23A_p0427	ENOG4105UQX	Mate efflux family protein
O23A_p0428	ENOG41075H3	AraC family transcriptional regulator
O23A_p0429	ENOG4107R1I	NAD-dependent malic enzyme
O23A_p0430	ENOG4105UYK	outer membrane protein a
O23A_p0432	ENOG4105UYK	outer membrane protein a
O23A_p0434	ENOG4105UYK	outer membrane protein a
O23A_p0438	ENOG4105C8J	)-transporter
O23A_p0439	ENOG4105D78	K07001 NTE family protein
O23A_p0440	ENOG4105BZU	Histidine kinase
O23A_p0441	ENOG4105ENT	Efflux transporter rnd family, mfp subunit
O23A_p0442	ENOG4105BZS	acriflavin resistance protein
O23A_p0444	ENOG4105CCT	upf0313 protein
O23A_p0450	ENOG4105EP9	oxidoreductase
O23A_p0451	ENOG4105NHU	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group (By similarity)
O23A_p0452	ENOG4105D8C	Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity)
O23A_p0453	ENOG4105E4C	Lytic transglycosylase catalytic
O23A_p0458	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
O23A_p0460	ENOG4105CIY	formyltetrahydrofolate deformylase
O23A_p0461	ENOG4105C66	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity)
O23A_p0464	ENOG4107QR8	Thioredoxin
O23A_p0465	ENOG4107YAK	holo-(acyl carrier protein) synthase 2
O23A_p0466	ENOG4107TT5	NLP P60 protein
O23A_p0467	ENOG4105EBA	Specifically methylates the adenine in position 1618 of 23S rRNA (By similarity)
O23A_p0470	ENOG4107N1Q	ErfK YbiS YcfS YnhG family protein
O23A_p0476	ENOG4105CS6	Rhs element vgr protein
O23A_p0478	ENOG4108WC9	type VI secretion system effector, hcp1 family
O23A_p0483	ENOG410679B	prophage CP4-57 regulatory protein alpA
O23A_p0497	ENOG4105W5Q	DNA repair protein (RadC
O23A_p0506	ENOG4105MAW	Antitoxin component of a toxin-antitoxin (TA) module. Labile antitoxin that counteracts the effect of the CbtA (YeeV) toxin. It does not bind to the cognate toxin but instead binds to MreB and FtsZ (the toxin targets), enhancing their polymerization by forming higher-order bundles
O23A_p0508	ENOG4107SV5	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. May be involved in the integration of spacer DNA into the CRISPR cassette (By similarity)
O23A_p0509	ENOG4107IIZ	CRISPR-associated helicase, Cas3
O23A_p0510	ENOG4105ENG	CRISPR-associated protein, Csy1 family
O23A_p0511	ENOG4105DZX	CRISPR-associated protein, Csy2 family
O23A_p0512	ENOG4105M6W	Crispr-associated protein, Csy3 family
O23A_p0513	ENOG4108Y1S	CRISPR-associated protein, Csy4 family
O23A_p0519	ENOG4107SSZ	Phosphatase
O23A_p0521	ENOG4107QPN	acyl-Coa dehydrogenase
O23A_p0522	ENOG4105BZS	acriflavin resistance protein
O23A_p0524	ENOG4105CA9	Pyruvate kinase
O23A_p0525	ENOG4106KNT	transcriptional regulator
O23A_p0527	ENOG4105CEQ	signal transduction histidine kinase regulating citrate malate metabolism
O23A_p0528	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
O23A_p0529	ENOG4108JJA	ABC, transporter
O23A_p0530	ENOG4105C42	Type I secretion membrane fusion protein (HlyD
O23A_p0531	ENOG4108JJA	ABC, transporter
O23A_p0533	ENOG4108RC6	RTX toxin
O23A_p0534	ENOG4105EUK	rtx toxin RtxA
O23A_p0537	ENOG4105CBM	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 (By similarity)
O23A_p0540	ENOG4105CHR	reductase
O23A_p0541	ENOG4105P66	Membrane
O23A_p0542	ENOG4105J4Q	Transcriptional regulator
O23A_p0543	ENOG4107SS6	2-dehydro-3-deoxygluconokinase
O23A_p0544	ENOG4108UHU	Aldolase
O23A_p0545	ENOG4105XEP	YhcH YjgK YiaL family protein
O23A_p0546	ENOG4105CAX	The 2-keto-3-deoxygluconate permease transports the degraded pectin products into the bacterial cell, where they serve as carbon and energy sources. This is a hydrogen coupled transport system (By similarity)
O23A_p0547	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
O23A_p0550	ENOG4105VYW	UPF0251 protein
O23A_p0553	ENOG4105EFZ	amidohydrolase
O23A_p0555	ENOG4105VQ0	flagellar hook-basal body complex protein fliE
O23A_p0556	ENOG4105C1F	The M ring may be actively involved in energy transduction (By similarity)
O23A_p0557	ENOG4105CS3	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
O23A_p0559	ENOG4108JIR	Flagellum-specific ATP synthase
O23A_p0563	ENOG4105D24	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
O23A_p0564	ENOG4105DD5	Flagellar motor switch protein
O23A_p0565	ENOG4105VTB	flagellar biosynthesis protein fliO
O23A_p0566	ENOG4105CN7	Flagellar biosynthetic protein FliP
O23A_p0567	ENOG4105VS8	Flagellar biosynthetic protein fliq
O23A_p0568	ENOG4105D19	Role in flagellar biosynthesis (By similarity)
O23A_p0569	ENOG4105D00	flagellar biosynthetic protein flhB
O23A_p0570	ENOG4105D7B	Flagellar biosynthesis protein flha
O23A_p0571	ENOG4105FZW	flagellar biosynthesis regulator FlhF
O23A_p0572	ENOG4107R21	site-determining protein
O23A_p0573	ENOG4105DN4	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
O23A_p0574	ENOG4108VYJ	response regulator receiver protein
O23A_p0575	ENOG4108KCC	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P) (By similarity)
O23A_p0576	ENOG4105CBS	Chea signal transduction histidine kinase
O23A_p0577	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
O23A_p0579	ENOG4108SEK	ompa motb domain protein
O23A_p0580	ENOG4107QJE	Chromosome Partitioning Protein
O23A_p0582	ENOG4108V3W	Chemotaxis protein, CheW
O23A_p0585	ENOG4105CA5	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes (By similarity)
O23A_p0586	ENOG41060IM	Heme exporter protein
O23A_p0587	ENOG4105X3C	heme exporter protein
O23A_p0588	ENOG4108ZKK	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH (By similarity)
O23A_p0589	ENOG4105DA4	cytochrome c-type biogenesis protein
O23A_p0590	ENOG4107QX9	Thiol disulfide interChange protein
O23A_p0591	ENOG4105KWW	Biogenesis protein
O23A_p0592	ENOG4105KWW	Biogenesis protein
O23A_p0593	ENOG410903C	(LipO)protein
O23A_p0594	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
O23A_p0595	ENOG4105M2J	Glutaredoxin
O23A_p0599	ENOG4108S7T	Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) (By similarity)
O23A_p0600	ENOG4108RXX	maleylacetoacetate isomerase
O23A_p0602	ENOG4108YYD	acetyltransferase
O23A_p0606	ENOG4105EZE	Cupin 4 family protein
O23A_p0607	ENOG4107QTF	adenylosuccinate lyase
O23A_p0608	ENOG41075W9	High frequency lysogenization protein HflD homolog
O23A_p0610	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
O23A_p0613	ENOG4108R99	pseudouridine synthase
O23A_p0615	ENOG4108YRF	PTS System
O23A_p0617	ENOG4105CXY	transporter
O23A_p0619	ENOG4105DM4	PTS System
O23A_p0627	ENOG4105S2T	inner membrane protein YbcI
O23A_p0632	ENOG4105F6H	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate (By similarity)
O23A_p0633	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
O23A_p0634	ENOG4105DK0	Indole-3-glycerol phosphate synthase
O23A_p0635	ENOG4108I0Q	anthranilate phosphoribosyltransferase
O23A_p0636	ENOG4108EFP	Anthranilate synthase component II
O23A_p0637	ENOG4105CRQ	synthase (Component I)
O23A_p0640	ENOG4105DB7	PHP domain protein
O23A_p0641	ENOG4107RTD	sua5 ycio yrdc ywlc family protein
O23A_p0643	ENOG4105K8I	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves (By similarity)
O23A_p0644	ENOG4105FE9	pseudouridine synthase
O23A_p0646	ENOG4105C29	acyl-CoA thioesterase
O23A_p0649	ENOG4108IG5	Transcriptional regulator
O23A_p0650	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
O23A_p0651	ENOG4105BZS	acriflavin resistance protein
O23A_p0652	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
O23A_p0653	ENOG4105C1B	dTDP-glucose 4-6-dehydratase
O23A_p0654	ENOG4108I19	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis (By similarity)
O23A_p0666	ENOG4105D3Q	Sugar transferase
O23A_p0668	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
O23A_p0670	ENOG4105DBZ	Dtdp-4-dehydrorhamnose reductase
O23A_p0672	ENOG4108URP	Dtdp-4-dehydrorhamnose 3,5-epimerase
O23A_p0673	ENOG4108QY5	Ferric enterobactin transport protein
O23A_p0675	ENOG4108YXG	UPF0502 protein
O23A_p0677	ENOG4105KR1	Trans-acting protein required for termination of DNA replication. Binds to DNA replication terminator sequences (terA to terF) to prevent the passage of replication forks. The termination efficiency will be affected by the affinity of this protein for the terminator sequence (By similarity)
O23A_p0680	ENOG4107RUY	(E1 component), alpha subunit
O23A_p0682	ENOG4105CPP	Dehydrogenase, E1 component
O23A_p0683	ENOG4107QSN	dihydrolipoamide acetyltransferase
O23A_p0684	ENOG4105VEQ	Cold shock protein
O23A_p0689	ENOG4105E43	Extracellular solute-binding protein, family 5
O23A_p0690	ENOG4108594	Permease of the drug metabolite transporter
O23A_p0692	ENOG4105CPI	Metal Dependent Phosphohydrolase
O23A_p0693	ENOG4105I08	Pseudouridine synthase
O23A_p0696	ENOG4108J59	Extracellular solute-binding protein, family 5
O23A_p0697	ENOG4108RE9	Phosphodiesterase
O23A_p0701	ENOG4107R88	Chemotaxis protein (CheV)
O23A_p0702	ENOG4105BZU	Histidine kinase
O23A_p0703	ENOG4105K88	Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body (By similarity)
O23A_p0704	ENOG4108ZC9	flagellar basal-body rod protein flgc
O23A_p0706	ENOG4105BZE	flagellar hook protein, FlgE
O23A_p0707	ENOG4108KPB	Flagellar basal-body rod protein FlgF
O23A_p0708	ENOG4105CGA	flagellar basal-body rod protein FlgG
O23A_p0709	ENOG4107W7W	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity)
O23A_p0710	ENOG4105D92	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity)
O23A_p0711	ENOG4108ZW7	flagellar rod assembly protein muramidase flgj
O23A_p0714	ENOG4105CJW	magnesium transporter
O23A_p0715	ENOG4105C9X	ppx gppa phosphatase
O23A_p0716	ENOG4105CUU	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) (By similarity)
O23A_p0719	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
O23A_p0720	ENOG4105BZU	Histidine kinase
O23A_p0721	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
O23A_p0722	ENOG4107QNR	UPF0135 protein
O23A_p0723	ENOG4108V3E	phosphoribosylglycinamide formyltransferase
O23A_p0724	ENOG4105CXB	phosphoribosylaminoimidazole synthetase
O23A_p0725	ENOG4105CZ5	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate (By similarity)
O23A_p0728	ENOG4108I9X	Isocitrate lyase
O23A_p0729	ENOG4107QP3	malate synthase g
O23A_p0732	ENOG4108Z6B	deaminase
O23A_p0733	ENOG4105C8U	phosphate abc transporter
O23A_p0734	ENOG4105E2Z	phosphate ABC transporter (Permease
O23A_p0736	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
O23A_p0738	ENOG4105C37	(CBS) domain
O23A_p0741	ENOG4105D5Q	Arginine ornithine antiporter
O23A_p0743	ENOG4105CDA	abc transporter atp-binding protein
O23A_p0744	ENOG4105E5Q	amino acid AbC transporter
O23A_p0745	ENOG4106PMH	Extracellular solute-binding protein family 3
O23A_p0746	ENOG4105BZU	Histidine kinase
O23A_p0747	ENOG4105CXY	transporter
O23A_p0748	ENOG4105BZU	Histidine kinase
O23A_p0749	ENOG4108KX4	response regulator
O23A_p0750	ENOG4105NXH	GreA GreB family elongation factor
O23A_p0755	ENOG4105G6Z	alkaline phosphatase
O23A_p0756	ENOG4105C9W	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity (By similarity)
O23A_p0757	ENOG4105DGU	Histone deacetylase
O23A_p0759	ENOG4105DVT	helicase
O23A_p0762	ENOG4105CGF	Aromatic amino acid aminotransferase
O23A_p0763	ENOG4105D7A	ATP-binding protein
O23A_p0766	ENOG4108EQH	DNA internalization-related competence protein ComEC Rec2
O23A_p0767	ENOG4105BZ1	(ABC) transporter
O23A_p0768	ENOG4105CHD	Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) (By similarity)
O23A_p0769	ENOG4105W49	UPF0434 protein
O23A_p0770	ENOG4105CET	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria (By similarity)
O23A_p0771	ENOG4105WH1	Two component transcriptional regulator luxr family
O23A_p0772	ENOG4105CII	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity)
O23A_p0792	ENOG4105KSC	Transcriptional regulator, TraR DksA family
O23A_p0802	ENOG4105ED4	portal protein
O23A_p0821	ENOG4108IYS	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
O23A_p0828	ENOG4105EQ2	LysR family Transcriptional regulator
O23A_p0829	ENOG4107EXU	Short-chain dehydrogenase reductase Sdr
O23A_p0831	ENOG4105Y3U	Transglycosylase-associated protein
O23A_p0832	ENOG4105F10	Catalyzes the hydrolysis of the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1- phosphate (lipid X) and UMP (By similarity)
O23A_p0834	ENOG4108R5K	PPIases accelerate the folding of proteins (By similarity)
O23A_p0835	ENOG4105C8N	cysteinyl-tRNA synthetase
O23A_p0842	ENOG410620I	Diguanylate cyclase
O23A_p0849	ENOG4108ZJT	translation initiation factor, Sui1
O23A_p0855	ENOG4105CZX	twitching motility protein
O23A_p0857	ENOG4105BZU	Histidine kinase
O23A_p0858	ENOG4108ESU	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Involved in the translocation of the substrate across the membrane (By similarity)
O23A_p0859	ENOG41080WI	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system (By similarity)
O23A_p0861	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
O23A_p0862	ENOG41080IJ	Diacylglycerol kinase
O23A_p0863	ENOG4108JQ1	Dehydrogenase
O23A_p0864	ENOG4105E66	phosphoriboisomerase A
O23A_p0865	ENOG4105MK2	5-formyltetrahydrofolate cyclo-ligase
O23A_p0869	ENOG4105DUK	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity)
O23A_p0871	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
O23A_p0872	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
O23A_p0874	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
O23A_p0875	ENOG4107QS8	(LipO)protein
O23A_p0876	ENOG4105C4Q	deoxyguanosinetriphosphate triphosphohydrolase-like protein
O23A_p0880	ENOG4108MK9	spermidine N(1)-acetyltransferase
O23A_p0881	ENOG4105C1J	atp-dependent rna helicase
O23A_p0886	ENOG4108Z4X	TRANSCRIPTIONal
O23A_p0889	ENOG4105EAB	amino acid AbC transporter
O23A_p0890	ENOG4105DRP	amino acid AbC transporter
O23A_p0891	ENOG4105CDA	abc transporter atp-binding protein
O23A_p0892	ENOG4105BZ8	glutamate synthase
O23A_p0893	ENOG4105CBC	glutamate synthase
O23A_p0894	ENOG4105N5T	Radical SAM Protein
O23A_p0896	ENOG4105C42	Type I secretion membrane fusion protein (HlyD
O23A_p0905	ENOG4105C85	amino acid
O23A_p0908	ENOG4105CF9	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation (By similarity)
O23A_p0909	ENOG4108HRN	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate (By similarity)
O23A_p0917	ENOG4105D01	(LipO)protein
O23A_p0918	ENOG4105EYK	Phosphatidylglycerophosphatase B
O23A_p0919	ENOG4105CJ0	Catalyzes the oxidation of erythronate-4-phosphate to 3- hydroxy-2-oxo-4-phosphonooxybutanoate (By similarity)
O23A_p0920	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
O23A_p0922	ENOG4105DI7	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity)
O23A_p0923	ENOG4107QTG	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA (By similarity)
O23A_p0924	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
O23A_p0925	ENOG4108S3P	Sporulation domain protein
O23A_p0926	ENOG4108Z0T	Part of a sulfur-relay system (By similarity)
O23A_p0927	ENOG4105EM2	membrane
O23A_p0928	ENOG4108MN8	Membrane
O23A_p0929	ENOG4107RHT	methyl-accepting chemotaxis sensory transducer with Pas Pac sensor
O23A_p0930	ENOG4105BZU	Histidine kinase
O23A_p0931	ENOG4108W1A	pseudouridine synthase
O23A_p0933	ENOG4105E6K	4-Hydroxyphenylpyruvate dioxygenase
O23A_p0934	ENOG4105F1J	Homogentisate 1,2-dioxygenase
O23A_p0936	ENOG4108RXX	maleylacetoacetate isomerase
O23A_p0938	ENOG4105CAQ	asparagine synthetase
O23A_p0940	ENOG4105CKD	glutathione-regulated potassium-efflux system protein
O23A_p0941	ENOG4105D4U	had-superfamily hydrolase, subfamily iia
O23A_p0942	ENOG4105EKD	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism (By similarity)
O23A_p0943	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
O23A_p0944	ENOG4105EE5	Membrane protein terC
O23A_p0947	ENOG4105CQB	FAD linked oxidase domain protein
O23A_p0949	ENOG4105KA0	thioesterase Superfamily protein
O23A_p0950	ENOG4105C1J	atp-dependent rna helicase
O23A_p0952	ENOG4105BZU	Histidine kinase
O23A_p0953	ENOG4105D3Y	Na H antiporter
O23A_p0954	ENOG4105DH5	Responsible for the end-turnover of tRNA specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis (By similarity)
O23A_p0956	ENOG4105EIY	sodium-type flagellar protein motY
O23A_p0957	ENOG4108UYE	Lactoylglutathione lyase
O23A_p0958	ENOG4105CSM	endonuclease III
O23A_p0959	ENOG4105DZB	Electron transport complex
O23A_p0960	ENOG4108UQQ	Electron transport complex
O23A_p0961	ENOG4105D6A	Electron transport complex
O23A_p0963	ENOG4108R3D	Electron transport complex
O23A_p0964	ENOG4105DGN	Electron transport complex
O23A_p0965	ENOG4108PCN	EamA-like transporter family
O23A_p0967	ENOG4107SDU	Methyl-accepting chemotaxis
O23A_p0968	ENOG4105RKW	reductase (By
O23A_p0969	ENOG4105CSX	c4-dicarboxylate anaerobic carrier
O23A_p0970	ENOG4105CHM	Aminotransferase
O23A_p0972	ENOG41090BQ	Glutaredoxin
O23A_p0974	ENOG4106HRJ	d-alanyl-d-alanine carboxypeptidase
O23A_p0975	ENOG4105CFI	type iii restriction protein res subunit
O23A_p0976	ENOG4105EFX	secretion protein, HlyD family
O23A_p0977	ENOG4105KK7	inner membrane protein YiaW
O23A_p0980	ENOG4108NEV	two component transcriptional regulator, LytTR family
O23A_p0981	ENOG4108HRK	Histidine kinase
O23A_p0982	ENOG4105CPI	Metal Dependent Phosphohydrolase
O23A_p0983	ENOG4108EKI	Dehydrogenase
O23A_p0985	ENOG4105EZI	multiple antibiotic resistance (MarC)-related protein
O23A_p0986	ENOG4107QSI	ABC, transporter
O23A_p0987	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
O23A_p0988	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
O23A_p0989	ENOG4105C3U	ABC transporter
O23A_p0990	ENOG4108JQ7	(ABC) transporter
O23A_p0991	ENOG4105DU1	integral membrane protein, terc
O23A_p0992	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
O23A_p0994	ENOG4105CK2	sodium dicarboxylate symporter
O23A_p0996	ENOG4105CD3	dihydroorotase
O23A_p0998	ENOG4108NVR	Methyl-accepting chemotaxis
O23A_p0999	ENOG4105K59	histidine triad (HIT) protein
O23A_p1006	ENOG4107QN8	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
O23A_p1007	ENOG4107RAB	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
O23A_p1008	ENOG4107SDU	Methyl-accepting chemotaxis
O23A_p1012	ENOG4105CNR	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
O23A_p1013	ENOG4105C8S	subunit m
O23A_p1014	ENOG4105D65	subunit l
O23A_p1015	ENOG41080EA	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
O23A_p1016	ENOG4107UFS	subunit j
O23A_p1017	ENOG4105P3U	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
O23A_p1018	ENOG4105CMZ	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone (By similarity)
O23A_p1019	ENOG4108IEH	NADH dehydrogenase subunit g
O23A_p1020	ENOG4107QIZ	NADH dehydrogenase
O23A_p1021	ENOG4105GKE	subunit e
O23A_p1022	ENOG4105CQV	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
O23A_p1023	ENOG4105ES3	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
O23A_p1024	ENOG4105KWU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
O23A_p1025	ENOG4105ER2	Ompa motb domain protein
O23A_p1028	ENOG4105HA9	of methanol dehydrogenase type
O23A_p1030	ENOG4105HPZ	Involved in the removal of murein from the sacculus. May also facilitate integration of nascent murein strands into the sacculus by cleaving the peptide bonds between neighboring strands in mature murein (By similarity)
O23A_p1031	ENOG4105EZ7	amino acid ABC transporter
O23A_p1032	ENOG4106TNF	Periplasmic binding protein
O23A_p1033	ENOG4105EAD	ABC transporter
O23A_p1034	ENOG4105CDA	abc transporter atp-binding protein
O23A_p1037	ENOG4105VFU	Rna-binding protein
O23A_p1038	ENOG4107RGM	aldo keto reductase
O23A_p1040	ENOG4108RU0	short-chain dehydrogenase reductase
O23A_p1043	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
O23A_p1044	ENOG4105CBN	LysR family transcriptional regulator
O23A_p1046	ENOG4105BZU	Histidine kinase
O23A_p1047	ENOG4108DBC	nitroreductase
O23A_p1050	ENOG4105D2S	major facilitator superfamily
O23A_p1051	ENOG4105DUM	transcriptional regulator, lysR family
O23A_p1052	ENOG4107R11	Transcriptional regulator
O23A_p1053	ENOG4108JEN	Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate (By similarity)
O23A_p1054	ENOG4105CAT	Cytidine monophosphate kinase
O23A_p1055	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
O23A_p1056	ENOG41080YA	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
O23A_p1058	ENOG4105CFV	Tetratricopeptide repeat protein
O23A_p1059	ENOG4106EG9	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) (By similarity)
O23A_p1062	ENOG4105FD2	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) (By similarity)
O23A_p1063	ENOG4105EIZ	Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity)
O23A_p1064	ENOG4105VRT	cytoplasmic protein
O23A_p1065	ENOG4108WBT	adenosyltransferase
O23A_p1068	ENOG4107S6Z	Na H antiporter
O23A_p1069	ENOG4107104	thymidine kinase
O23A_p1071	ENOG4108RMJ	sensory transduction regulator
O23A_p1072	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
O23A_p1076	ENOG4105E3S	small subunit
O23A_p1077	ENOG4105QA4	4Fe-4S Ferredoxin, iron-sulfur binding domain protein
O23A_p1078	ENOG4105CJ5	hydrogenase 2 b cytochrome subunit
O23A_p1079	ENOG4105DPX	Hydrogenase, large subunit
O23A_p1080	ENOG4108USZ	hydrogenase
O23A_p1081	ENOG4108WGS	hydrogenase 2-specific chaperone
O23A_p1083	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
O23A_p1084	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
O23A_p1086	ENOG4105EFJ	Part of the ABC transporter complex NikABCDE involved in nickel import. Responsible for energy coupling to the transport system (By similarity)
O23A_p1087	ENOG4107RSS	Hydrogenase accessory protein HypB
O23A_p1089	ENOG4105WMM	Probably plays a role in a hydrogenase nickel cofactor insertion step (By similarity)
O23A_p1090	ENOG4105C45	hydrogenase expression formation protein (HypE)
O23A_p1091	ENOG4105CQS	hydrogenase expression formation protein HypD
O23A_p1092	ENOG4105WRB	Hydrogenase assembly chaperone hypC hupF
O23A_p1094	ENOG4105EM7	Selenocysteine-specific translation elongation factor
O23A_p1095	ENOG4105C1Y	Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis (By similarity)
O23A_p1096	ENOG4108MG9	hydrogenase 3 maturation protease
O23A_p1097	ENOG4105I6X	formate hydrogenlyase maturation
O23A_p1098	ENOG4105C47	NADH ubiquinone oxidoreductase 20 kda subunit
O23A_p1100	ENOG4105CQV	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
O23A_p1101	ENOG4107TDF	Formate hydrogenlyase subunit 4
O23A_p1102	ENOG4108JPZ	Monovalent cation H antiporter subunit D
O23A_p1103	ENOG4108MFN	small subunit of hydrogenase-3, iron-sulfur protein (part of formate hydrogenlyase (FHL) complex)
O23A_p1104	ENOG4105DFH	Transport of potassium into the cell (By similarity)
O23A_p1107	ENOG4108RC0	Electron transport protein
O23A_p1108	ENOG4107QIW	Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity)
O23A_p1109	ENOG4107QIW	Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity)
O23A_p1112	ENOG4107H9G	Necessary for formate dehydrogenase activity (By similarity)
O23A_p1113	ENOG4105F3K	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity)
O23A_p1114	ENOG4105CJX	Molecular chaperone. Has ATPase activity (By similarity)
O23A_p1116	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
O23A_p1117	ENOG4105CFX	Catalyzes the ferrous insertion into protoporphyrin IX (By similarity)
O23A_p1118	ENOG4105WJG	Glutathione
O23A_p1119	ENOG4107RE1	Inosine-guanosine kinase
O23A_p1120	ENOG4105C8Q	Methyl-accepting chemotaxis
O23A_p1123	ENOG4105BZU	Histidine kinase
O23A_p1124	ENOG4107QQ4	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans (By similarity)
O23A_p1126	ENOG4105F3T	(LipO)protein
O23A_p1128	ENOG4108IQC	2,3-dihydroxybenzoate-AMP ligase
O23A_p1129	ENOG4105WQI	isochorismatase
O23A_p1130	ENOG4105CEY	Amp-dependent synthetase and ligase
O23A_p1131	ENOG4105X17	23-dihydro-2,3-dihydroxybenzoate dehydrogenase
O23A_p1133	ENOG4105C0W	non-ribosomal peptide synthetase
O23A_p1134	ENOG4105J76	Periplasmic binding protein
O23A_p1135	ENOG4108TSE	Transferase
O23A_p1136	ENOG4105E0A	ABC, transporter
O23A_p1137	ENOG4105TVJ	transport system, permease
O23A_p1138	ENOG4105DQ5	transport system permease protein
O23A_p1139	ENOG4105D05	Receptor
O23A_p1142	ENOG4105QZU	Inner membrane protein YfeZ
O23A_p1143	ENOG4107QUT	magnesium and cobalt transport protein CorA
O23A_p1145	ENOG4105DWH	electron transfer flavoprotein-ubiquinone oxidoreductase
O23A_p1146	ENOG4105DWH	electron transfer flavoprotein-ubiquinone oxidoreductase
O23A_p1147	ENOG4105BZJ	Electron transfer flavoprotein
O23A_p1148	ENOG4105C10	Electron transfer flavoprotein
O23A_p1149	ENOG4107QM1	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine (By similarity)
O23A_p1150	ENOG4105CMY	5-enolpyruvylshikimate-3-phosphate synthase
O23A_p1151	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
O23A_p1152	ENOG4108NVR	Methyl-accepting chemotaxis
O23A_p1153	ENOG4105D4P	Coproporphyrinogen iii oxidase
O23A_p1154	ENOG4105DVS	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
O23A_p1155	ENOG4105DS1	cytochrome b561
O23A_p1156	ENOG4105SG9	biopolymer transport protein, ExbD
O23A_p1159	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
O23A_p1160	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
O23A_p1164	ENOG4105FQ6	thiopurine methyltransferase
O23A_p1165	ENOG4107QXK	peptidase
O23A_p1166	ENOG4108BY2	phosphohistidine phosphatase
O23A_p1168	ENOG4108IPJ	Membrane
O23A_p1169	ENOG4108J59	Extracellular solute-binding protein, family 5
O23A_p1170	ENOG4105CZI	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
O23A_p1171	ENOG4108JA2	transcriptioN-repair coupling factor
O23A_p1173	ENOG4105D60	lipoprotein releasing system transmembrane protein
O23A_p1174	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
O23A_p1175	ENOG4105D60	lipoprotein releasing system transmembrane protein
O23A_p1178	ENOG4105DEA	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation
O23A_p1179	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
O23A_p1180	ENOG4105CHN	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
O23A_p1181	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
O23A_p1183	ENOG4105K70	DNA-binding protein
O23A_p1184	ENOG4105EIN	peptidylprolyl cis-trans isomerase
O23A_p1185	ENOG4105C5H	ABC transporter
O23A_p1186	ENOG4107R08	Integrase
O23A_p1193	ENOG4105CYV	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures (By similarity)
O23A_p1202	ENOG4107QN1	sodium solute
O23A_p1203	ENOG41062QD	Membrane
O23A_p1206	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
O23A_p1207	ENOG4105BZG	amino acid carrier protein
O23A_p1208	ENOG410870W	N-acetyltransferase
O23A_p1210	ENOG4106HK8	GPR1 FUN34 yaaH family protein
O23A_p1218	ENOG4105E39	Enoyl-CoA hydratase
O23A_p1219	ENOG4107QX3	carboxylase
O23A_p1220	ENOG4105C1G	acyl-Coa dehydrogenase
O23A_p1221	ENOG4105C26	Dehydrogenase
O23A_p1222	ENOG4105C1G	acyl-Coa dehydrogenase
O23A_p1223	ENOG4105E39	Enoyl-CoA hydratase
O23A_p1224	ENOG4105E39	Enoyl-CoA hydratase
O23A_p1225	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
O23A_p1227	ENOG4105CHR	reductase
O23A_p1228	ENOG4105D5Q	Arginine ornithine antiporter
O23A_p1229	ENOG4105HF0	Membrane
O23A_p1242	ENOG4105K3G	Periplasmic Protein
O23A_p1245	ENOG41062B0	ABC transporter, permease
O23A_p1246	ENOG4107R9N	ABC transporter
O23A_p1247	ENOG4105C2J	ABC transporter
O23A_p1248	ENOG4107R5U	Periplasmic binding protein LacI transcriptional regulator
O23A_p1250	ENOG4108KB2	LysR family Transcriptional regulator
O23A_p1252	ENOG4105CS2	ec 3.2.1.21
O23A_p1253	ENOG4105CHR	reductase
O23A_p1255	ENOG4105CBN	LysR family transcriptional regulator
O23A_p1256	ENOG4105EFU	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin (By similarity)
O23A_p1258	ENOG4105DUM	transcriptional regulator, lysR family
O23A_p1260	ENOG4105NWR	lipid A biosynthesis (Kdo)2-(Lauroyl)-lipid IVA acyltransferase
O23A_p1262	ENOG4105NWR	lipid A biosynthesis (Kdo)2-(Lauroyl)-lipid IVA acyltransferase
O23A_p1265	ENOG4105BZU	Histidine kinase
O23A_p1268	ENOG4105CQ2	DNA polymerase
O23A_p1270	ENOG4107QI1	Mate efflux family protein
O23A_p1271	ENOG4105W1I	UPF0253 protein
O23A_p1272	ENOG4108R6K	riboflavin synthase, subunit alpha
O23A_p1274	ENOG4107UW8	HAD-superfamily hydrolase subfamily IA variant 3
O23A_p1275	ENOG4108HH9	Catalyzes two reactions the first one is the production of beta-formyl glycinamide ribonucleotide (GAR) from formate, ATP and beta GAR
O23A_p1276	ENOG4108SXK	Transporter Drug Metabolite Exporter family
O23A_p1277	ENOG4108V3G	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity)
O23A_p1284	ENOG4105XW2	UPF0263 protein
O23A_p1286	ENOG4108VKV	Monofunctional biosynthetic peptidoglycan transglycosylase
O23A_p1288	ENOG4105VJP	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell (By similarity)
O23A_p1289	ENOG4107QMS	site-determining protein
O23A_p1290	ENOG4105K7U	Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization (By similarity)
O23A_p1291	ENOG4105VNG	YcgL domain-containing protein
O23A_p1292	ENOG4105CVE	Lytic murein transglycosylase
O23A_p1293	ENOG4105EJQ	L-serine dehydratase
O23A_p1295	ENOG4105EJQ	L-serine dehydratase
O23A_p1296	ENOG4105NBK	UPF0345 protein
O23A_p1297	ENOG4105CK2	sodium dicarboxylate symporter
O23A_p1299	ENOG4105CHU	acetyl-coa acetyltransferase
O23A_p1300	ENOG4105D58	Diguanylate phosphodiesterase
O23A_p1301	ENOG4105CKF	membrane protein involved in aromatic hydrocarbon degradation
O23A_p1302	ENOG4105CKF	membrane protein involved in aromatic hydrocarbon degradation
O23A_p1311	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
O23A_p1312	ENOG4105CHU	acetyl-coa acetyltransferase
O23A_p1313	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
O23A_p1314	ENOG4108Z8G	Alkylphosphonate utilization operon protein PhnA
O23A_p1321	ENOG4105BZU	Histidine kinase
O23A_p1322	ENOG4108DG9	Smr protein MutS2
O23A_p1323	ENOG4105C76	Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue (By similarity)
O23A_p1324	ENOG4105D10	5-enolpyruvylshikimate-3-phosphate phospholyase
O23A_p1327	ENOG4105C1J	atp-dependent rna helicase
O23A_p1330	ENOG4105E0U	tyrosine-specific transport protein
O23A_p1331	ENOG4107B7Y	DNA-binding transcriptional regulator FruR
O23A_p1332	ENOG4105DTZ	bifunctional PTS system fructose-specific transporter subunit IIA HPr protein
O23A_p1333	ENOG4105DE4	1-phosphofructokinase
O23A_p1334	ENOG4105DM4	PTS System
O23A_p1335	ENOG4105XZD	Fe-S protein
O23A_p1336	ENOG4105CA3	membrane-bound lytic murein transglycosylase
O23A_p1337	ENOG4105XPH	Ferredoxin
O23A_p1338	ENOG4105E05	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
O23A_p1339	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
O23A_p1341	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
O23A_p1342	ENOG4108HWB	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
O23A_p1343	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
O23A_p1348	ENOG4105C22	threonyL-tRNA synthetase
O23A_p1349	ENOG4108UUX	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity)
O23A_p1351	ENOG4108YZX	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity)
O23A_p1352	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
O23A_p1353	ENOG4105C6A	phenylalanyl-tRNA synthetase (beta subunit)
O23A_p1354	ENOG4108ZUF	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
O23A_p1355	ENOG4105BZU	Histidine kinase
O23A_p1358	ENOG4105NDF	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity)
O23A_p1360	ENOG4108KHX	Diguanylate cyclase
O23A_p1361	ENOG4105ETE	Transcriptional regulator (LacI family
O23A_p1362	ENOG4108RVA	ribokinase
O23A_p1363	ENOG4105E9V	Periplasmic binding protein LacI transcriptional regulator
O23A_p1364	ENOG4105CNN	ABC, transporter
O23A_p1365	ENOG4105C2J	ABC transporter
O23A_p1366	ENOG4105MRB	Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose (By similarity)
O23A_p1367	ENOG4108K3A	Glutathione S-transferase
O23A_p1370	ENOG4105CB3	Required for the thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32) (By similarity)
O23A_p1371	ENOG4105Q9Y	Universal stress protein
O23A_p1372	ENOG4105DS0	Transcriptional regulator, Crp Fnr family
O23A_p1375	ENOG4105C59	p-type ATPase
O23A_p1377	ENOG4105D6P	C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex (By similarity)
O23A_p1380	ENOG4105EUH	cytochrome C oxidase, cbb3-type, subunit i
O23A_p1382	ENOG4108ZGC	gaf domain protein
O23A_p1383	ENOG41073DY	may be a structural element that influences the osmotic activation of ProP at a post-translational level (By similarity)
O23A_p1384	ENOG4105CN1	protease
O23A_p1385	ENOG4105CD8	aminopeptidase N
O23A_p1387	ENOG4105C7I	Dehydrogenase
O23A_p1388	ENOG4107QYT	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor (By similarity)
O23A_p1389	ENOG4108T7E	Contributes to the efficiency of the cell division process by stabilizing the polymeric form of the cell division protein FtsZ. Acts by promoting interactions between FtsZ protofilaments and suppressing the GTPase activity of FtsZ (By similarity)
O23A_p1390	ENOG4105C4H	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA (By similarity)
O23A_p1392	ENOG4105C5H	ABC transporter
O23A_p1394	ENOG4108RKI	Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl- ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)- decenoyl-ACP. Can catalyze the dehydratase reaction for beta- hydroxyacyl-ACPs with saturated chain lengths up to 16 0, being most active on intermediate chain length (By similarity)
O23A_p1395	ENOG4105DAN	ATP-dependent protease
O23A_p1409	ENOG4105X2V	dna damage-inducible protein
O23A_p1411	ENOG4105PDP	Short chain dehydrogenase
O23A_p1419	ENOG4105DXD	2-methylcitrate dehydratase
O23A_p1420	ENOG4105BZN	citrate synthase
O23A_p1421	ENOG4105CR4	methylisocitrate lyase
O23A_p1423	ENOG4105F1S	paraquat-inducible protein a
O23A_p1424	ENOG4105DY2	Paraquat-inducible protein b
O23A_p1425	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
O23A_p1429	ENOG4105F8V	Hydrolase, tatD family
O23A_p1430	ENOG4107QRG	dna polymerase iii
O23A_p1431	ENOG4108ZMD	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity)
O23A_p1432	ENOG4105HHA	aminodeoxychorismate lyase
O23A_p1433	ENOG4105YAZ	4-amino-4-deoxychorismate lyase
O23A_p1434	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
O23A_p1435	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
O23A_p1436	ENOG4105CHR	reductase
O23A_p1437	ENOG4105CJF	Malonyl coA-acyl carrier protein transacylase
O23A_p1438	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
O23A_p1439	ENOG4105C6B	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA (By similarity)
O23A_p1440	ENOG4105VGS	50s ribosomal protein l32
O23A_p1441	ENOG4105FCQ	metal-binding, possibly nucleic acid-binding protein
O23A_p1442	ENOG4108UHJ	MAF-like protein
O23A_p1443	ENOG4108YZS	Had-superfamily hydrolase, subfamily ia, variant 1
O23A_p1444	ENOG4105EI2	Pseudouridine synthase
O23A_p1445	ENOG4105C03	ribonuclease
O23A_p1447	ENOG4105CJ3	phosphate transporter
O23A_p1448	ENOG4105DHP	deoxycytidine triphosphate deaminase
O23A_p1449	ENOG4105DBI	uridine monophosphokinase
O23A_p1450	ENOG4105D1F	ATP-binding protein
O23A_p1451	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
O23A_p1452	ENOG4108TGY	Glutathione S-transferase
O23A_p1453	ENOG4105VSY	K01512 acylphosphatase EC 3.6.1.7
O23A_p1454	ENOG4108N3W	hemolysin secretion protein
O23A_p1455	ENOG4105DR4	Methyltransferase
O23A_p1456	ENOG4105FAT	Acyl-transferase
O23A_p1458	ENOG4105D4F	Synthesizes selenophosphate from selenide and ATP (By similarity)
O23A_p1459	ENOG4105CR7	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA (By similarity)
O23A_p1460	ENOG4105C5X	domain protein
O23A_p1461	ENOG4105KW6	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance (By similarity)
O23A_p1463	ENOG4105CQ7	ATP-dependent helicase
O23A_p1465	ENOG4105WH1	Two component transcriptional regulator luxr family
O23A_p1466	ENOG4105DWD	nucleoside recognition domain protein
O23A_p1467	ENOG4105KDX	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection (By similarity)
O23A_p1468	ENOG4107QMP	dna polymerase iii subunits gamma and tau
O23A_p1469	ENOG4109003	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity)
O23A_p1470	ENOG4105WD1	Membrane
O23A_p1471	ENOG4105FBT	Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs (By similarity)
O23A_p1475	ENOG4105CEY	Amp-dependent synthetase and ligase
O23A_p1476	ENOG4108MXF	Alpha Beta Hydrolase
O23A_p1478	ENOG41072GX	Peptidase M22 Glycoprotease
O23A_p1479	ENOG4105DVT	helicase
O23A_p1481	ENOG4105E21	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity)
O23A_p1482	ENOG4105CEK	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity)
O23A_p1484	ENOG4105CIH	Imidazole acetol-phosphate transaminase
O23A_p1487	ENOG4108UJE	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity)
O23A_p1488	ENOG4105CJV	Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase
O23A_p1489	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
O23A_p1491	ENOG4105BZU	Histidine kinase
O23A_p1492	ENOG4105C0S	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity)
O23A_p1493	ENOG4105K8F	Phosphoribosyl-amp cyclohydrolase
O23A_p1495	ENOG4105D29	Helix-turn-helix type 11 domain protein
O23A_p1496	ENOG4105CEY	Amp-dependent synthetase and ligase
O23A_p1498	ENOG4105CSX	c4-dicarboxylate anaerobic carrier
O23A_p1500	ENOG4107MBR	17 kDa surface antigen
O23A_p1504	ENOG4105EHG	Permease protein
O23A_p1508	ENOG4108VWS	Yaeq family
O23A_p1517	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
O23A_p1520	ENOG4105K6T	rare lipoprotein A
O23A_p1522	ENOG4105DUC	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division (By similarity)
O23A_p1523	ENOG4105DAH	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF (By similarity)
O23A_p1524	ENOG4105GHU	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid partitioning. Probably acts via its interaction with MukB and MukE. Overexpression results in anucleate cells. It has a calcium binding activity (By similarity)
O23A_p1525	ENOG4106371	Methyltransferase
O23A_p1526	ENOG4107S90	membrAne
O23A_p1528	ENOG4105CTQ	phosphohexokinase
O23A_p1533	ENOG4105CH2	amidohydrolase
O23A_p1534	ENOG4105PAD	Hydrolase
O23A_p1535	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
O23A_p1538	ENOG4105CPB	ATP-dependent endonuclease of the OLD family
O23A_p1541	ENOG4105VP0	transcriptional regulator, lysR family
O23A_p1542	ENOG4105EJ9	Membrane
O23A_p1543	ENOG4106IUH	DTW domain containing protein
O23A_p1545	ENOG4105CPF	Cell wall formation (By similarity)
O23A_p1547	ENOG4108V06	Glutathione peroxidase
O23A_p1548	ENOG4105C1J	atp-dependent rna helicase
O23A_p1549	ENOG4105K5X	acetyltransferase
O23A_p1552	ENOG4105KK4	UPF0060 membrane protein
O23A_p1559	ENOG41061CK	Antibiotic biosynthesis monooxygenase
O23A_p1560	ENOG4107XGF	functions in a salvage pathway. Uses pyridoxamine (By similarity)
O23A_p1564	ENOG4105D1N	poly(r)-hydroxyalkanoic acid synthase, class
O23A_p1566	ENOG4105WQ3	Rna-binding protein
O23A_p1568	ENOG4105BZ1	(ABC) transporter
O23A_p1569	ENOG4105BZ1	(ABC) transporter
O23A_p1570	ENOG4105BZU	Histidine kinase
O23A_p1571	ENOG4105K63	Thioredoxin
O23A_p1572	ENOG4105C8P	)-transporter
O23A_p1573	ENOG4107QQN	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties (By similarity)
O23A_p1578	ENOG4105CRQ	synthase (Component I)
O23A_p1580	ENOG4105C44	Serine transporter
O23A_p1581	ENOG4107QV7	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system) (By similarity)
O23A_p1582	ENOG4105C9U	ATP-dependent DNA helicase RecQ
O23A_p1583	ENOG4105CYN	Serine protein kinase
O23A_p1585	ENOG4105ED1	spovr family
O23A_p1587	ENOG4105DKR	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity)
O23A_p1588	ENOG410635M	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein (By similarity)
O23A_p1589	ENOG4105DQR	SNARE associated Golgi
O23A_p1591	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
O23A_p1592	ENOG4105D0C	transport protein
O23A_p1593	ENOG4105CHQ	Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella (By similarity)
O23A_p1597	ENOG4108MRH	transcriptional regulatory protein
O23A_p1598	ENOG4105CEQ	signal transduction histidine kinase regulating citrate malate metabolism
O23A_p1599	ENOG4105E2R	ROK family
O23A_p1600	ENOG4105C8Q	Methyl-accepting chemotaxis
O23A_p1601	ENOG4105K5B	UPF0225 protein
O23A_p1602	ENOG4107R5Y	anaerobic glycerol-3-phosphate dehydrogenase, subunit A
O23A_p1604	ENOG4105CHG	glycolate oxidase (iron-sulfur subunit)
O23A_p1606	ENOG4105JJ8	Cytochrome c nitrite reductase, pentaheme subunit
O23A_p1607	ENOG4105D3S	4Fe-4S Ferredoxin, iron-sulfur binding domain protein
O23A_p1608	ENOG4105DVI	reductase, NrfD
O23A_p1609	ENOG4105DA4	cytochrome c-type biogenesis protein
O23A_p1610	ENOG4107QX9	Thiol disulfide interChange protein
O23A_p1611	ENOG4108DMF	Cytochrome C biogenesis protein
O23A_p1613	ENOG41061WM	D-Alanyl-D-Alanine
O23A_p1614	ENOG4105C0F	tryptophanase EC 4.1.99.1
O23A_p1615	ENOG4105EXX	Deoxyribodipyrimidine photolyase-related protein
O23A_p1616	ENOG4105MWK	D-amino acid dehydrogenase, small subunit
O23A_p1621	ENOG4105DSS	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation (By similarity)
O23A_p1622	ENOG4105DZ2	Transcriptional regulator
O23A_p1624	ENOG4105E0K	tonB-dependent siderophore receptor
O23A_p1625	ENOG4105UEI	Transcriptional Regulator AraC Family
O23A_p1628	ENOG4105CR8	Transcriptional regulator
O23A_p1629	ENOG4108RYK	Nad-dependent epimerase dehydratase
O23A_p1633	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
O23A_p1634	ENOG4105DDY	UPF0142 protein ycaO
O23A_p1635	ENOG4105TMB	Formate nitrite transporter
O23A_p1636	ENOG4105C6N	Formate acetyltransferase
O23A_p1639	ENOG4105CH8	Succinyl-CoA ligase ADP-forming subunit alpha
O23A_p1640	ENOG4105CMV	Succinyl-CoA synthetase subunit beta
O23A_p1641	ENOG4105C7S	Dehydrogenase
O23A_p1642	ENOG4105C7P	2-oxoglutarate dehydrogenase, E1
O23A_p1643	ENOG4105E33	succinate dehydrogenase
O23A_p1644	ENOG4105C00	Succinate dehydrogenase (Flavoprotein subunit)
O23A_p1645	ENOG4105N1I	succinate dehydrogenase, hydrophobic membrane anchor protein
O23A_p1646	ENOG4108UTY	succinate dehydrogenase, cytochrome b556 subunit
O23A_p1648	ENOG4105BZN	citrate synthase
O23A_p1651	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
O23A_p1652	ENOG4105CWG	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34 (By similarity)
O23A_p1654	ENOG4105CEE	C4-dicarboxylate transporter
O23A_p1657	ENOG4108VKG	metal-dependent hydrolase
O23A_p1660	ENOG4105NRA	50s ribosomal protein l31 type b
O23A_p1663	ENOG4105CNN	ABC, transporter
O23A_p1664	ENOG4105C2J	ABC transporter
O23A_p1665	ENOG4105DMK	Periplasmic binding protein LacI transcriptional regulator
O23A_p1666	ENOG4105EF1	ribulokinase
O23A_p1668	ENOG4105CAC	Catalyzes the conversion of L-arabinose to L-ribulose (By similarity)
O23A_p1669	ENOG4105ETT	transcriptional Regulator, LysR family
O23A_p1670	ENOG4105CHM	Aminotransferase
O23A_p1674	ENOG4105CJB	Exodeoxyribonuclease I
O23A_p1676	ENOG4107R49	K07407 alpha-galactosidase EC 3.2.1.22
O23A_p1679	ENOG41067MG	lrgb family
O23A_p1681	ENOG4107T42	This enzyme scavenge exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis (By similarity)
O23A_p1682	ENOG4108IQE	Amp-dependent synthetase and ligase
O23A_p1683	ENOG4105MH2	YfcL protein
O23A_p1685	ENOG4105EE5	Membrane protein terC
O23A_p1686	ENOG4105UYK	outer membrane protein a
O23A_p1687	ENOG4108KHX	Diguanylate cyclase
O23A_p1688	ENOG4108WS1	
O23A_p1690	ENOG41090A4	Pterin carbinolamine dehydratase
O23A_p1691	ENOG4105MIR	Phenylalanine 4-monooxygenase
O23A_p1692	ENOG4106K28	UPF0283 membrane protein
O23A_p1693	ENOG4105CM6	amino acid regulated cytosolic protein
O23A_p1695	ENOG4105YYT	phage shock protein B
O23A_p1696	ENOG41087YS	Phage shock protein A
O23A_p1697	ENOG4105E51	psp operon transcriptional activator
O23A_p1698	ENOG4108J59	Extracellular solute-binding protein, family 5
O23A_p1699	ENOG4108I5W	peptide transport system, permease protein
O23A_p1700	ENOG4108EU3	peptide transport system, permease
O23A_p1701	ENOG4108JQ3	Peptide ABC transporter ATP-binding protein
O23A_p1702	ENOG4108JQ2	peptide transport system atp-binding protein
O23A_p1703	ENOG4105FR9	TRNA-(Ms 2 io 6 A)-hydroxylase
O23A_p1704	ENOG4105CBA	glutamine phosphoribosylpyrophosphate amidotransferase
O23A_p1705	ENOG4105E96	Colicin v production protein
O23A_p1706	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
O23A_p1707	ENOG4105D1H	recombination factor protein RarA
O23A_p1709	ENOG4107Y7W	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) (By similarity)
O23A_p1710	ENOG4105CNU	cell division protein FtsK
O23A_p1711	ENOG4105EW9	transcriptional regulator AsnC family
O23A_p1712	ENOG4105DCF	alanine dehydrogenase
O23A_p1713	ENOG4105C3M	thioredoxin reductase
O23A_p1714	ENOG4105BZU	Histidine kinase
O23A_p1715	ENOG4107MBR	17 kDa surface antigen
O23A_p1716	ENOG4108R4Z	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine (By similarity)
O23A_p1717	ENOG4105DWA	May conjugate Arg from its aminoacyl-tRNA to the N- termini of proteins containing an N-terminal aspartate or glutamate
O23A_p1718	ENOG4105K9U	however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity)
O23A_p1719	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
O23A_p1720	ENOG4105KAE	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation (By similarity)
O23A_p1721	ENOG4105VEQ	Cold shock protein
O23A_p1722	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
O23A_p1725	ENOG4105CS6	Rhs element vgr protein
O23A_p1732	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
O23A_p1748	ENOG4105CS6	Rhs element vgr protein
O23A_p1749	ENOG4108WC9	type VI secretion system effector, hcp1 family
O23A_p1750	ENOG4105CHH	sulfate transporter
O23A_p1757	ENOG4105IQJ	Involved in biosynthesis of the thiamine precursor thiazole (By similarity)
O23A_p1761	ENOG4105C2C	drug resistance transporter, Bcr CflA
O23A_p1764	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
O23A_p1775	ENOG4107QXP	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
O23A_p1777	ENOG4107QZM	n-acetylglutamate synthase
O23A_p1778	ENOG4105CFH	Aspartokinase
O23A_p1780	ENOG4107T7U	Sulfatase
O23A_p1781	ENOG4105EBE	Peptidase U61, LD-carboxypeptidase A
O23A_p1783	ENOG4105K8R	UPF0145 protein
O23A_p1784	ENOG4105CEP	NADH dehydrogenase
O23A_p1787	ENOG4105DPN	Oligoendopeptidase f
O23A_p1788	ENOG4105DPN	Oligoendopeptidase f
O23A_p1789	ENOG4105CKW	Inner membrane protein yedI
O23A_p1791	ENOG4107QIK	phosphoribosylformylglycinamidine synthase
O23A_p1792	ENOG4105CHQ	Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella (By similarity)
O23A_p1793	ENOG4105VPD	cellular component movement
O23A_p1794	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
O23A_p1795	ENOG4105CNE	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
O23A_p1796	ENOG4105N21	Membrane
O23A_p1797	ENOG4105CUT	histidyl-tRNA synthetase
O23A_p1798	ENOG4105C4E	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (By similarity)
O23A_p1799	ENOG4105HSZ	Cytoskeletal protein that is involved in cell-shape control through regulation of the length of the long axis (By similarity)
O23A_p1801	ENOG4105C55	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
O23A_p1802	ENOG4108UGX	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity)
O23A_p1803	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
O23A_p1805	ENOG4108ZIT	Ferredoxin, 2FE-2S
O23A_p1806	ENOG4105C9I	Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB
O23A_p1807	ENOG4108SWN	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA (By similarity)
O23A_p1809	ENOG4108Z4V	iron-sulfur cluster assembly
O23A_p1810	ENOG4107XTC	May be involved in the formation or repair of Fe-S clusters present in iron-sulfur proteins
O23A_p1811	ENOG4105C3J	Cysteine desulfurase
O23A_p1812	ENOG4108ZF1	Transcriptional regulator, BadM Rrf2 family
O23A_p1813	ENOG4105CVS	RNA methyltransferase TrmH family, group 1
O23A_p1814	ENOG4105XPQ	lipid carrier protein
O23A_p1815	ENOG4105CFP	Peptidase U32
O23A_p1816	ENOG4106RZ4	Peptidase U32
O23A_p1818	ENOG4105KHC	sulfurtransferase
O23A_p1819	ENOG4107RAB	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
O23A_p1820	ENOG4107QN8	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
O23A_p1821	ENOG4105VIE	preprotein translocase, subunit YajC
O23A_p1822	ENOG4105C6U	Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity)
O23A_p1823	ENOG4105E2N	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) (By similarity)
O23A_p1824	ENOG4105W87	Cbs domain
O23A_p1825	ENOG4105D3R	alkyl hydroperoxide reductase
O23A_p1829	ENOG4105CBI	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
O23A_p1830	ENOG4105KE9	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity)
O23A_p1831	ENOG4105D43	The glycine cleavage system catalyzes the degradation of glycine (By similarity)
O23A_p1832	ENOG4105EAK	ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family
O23A_p1833	ENOG4105D0A	hydroxylase
O23A_p1836	ENOG4107YUN	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division (By similarity)
O23A_p1837	ENOG4107QKC	Oxidoreductase alpha (molybdopterin) subunit
O23A_p1838	ENOG4107H9G	Necessary for formate dehydrogenase activity (By similarity)
O23A_p1839	ENOG4105EJC	lysr family transcriptional regulator
O23A_p1840	ENOG4105E5M	Multidrug resistance protein D
O23A_p1841	ENOG4108RZA	ABC transporter
O23A_p1842	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
O23A_p1843	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
O23A_p1845	ENOG4105CYM	Glutathione S-transferase
O23A_p1848	ENOG4108NVR	Methyl-accepting chemotaxis
O23A_p1851	ENOG4105DUF	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively (By similarity)
O23A_p1853	ENOG4105JKQ	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Binds vitamin B12 and delivers it to the periplasmic surface of BtuC (By similarity)
O23A_p1856	ENOG4105MQ3	flagellar protein FliS
O23A_p1859	ENOG4105I03	Flagellin
O23A_p1861	ENOG4105EN6	Membrane
O23A_p1863	ENOG4105D8I	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS (By similarity)
O23A_p1865	ENOG4108JQB	penicillin-binding protein 1C
O23A_p1866	ENOG4105DN3	alpha-2-macroglobulin domain protein
O23A_p1867	ENOG4107QMW	pyridine nucleotide-disulfide oxidoreductase
O23A_p1868	ENOG4105BZU	Histidine kinase
O23A_p1869	ENOG4105F1A	Pyruvate formate-lyase
O23A_p1872	ENOG41090SZ	ABC-2 type transporter
O23A_p1875	ENOG4107V1M	polysaccharide export protein
O23A_p1877	ENOG4107VDP	teichoic acid biosynthesis
O23A_p1879	ENOG4105E12	capsule polysaccharide
O23A_p1880	ENOG41084CK	capsule polysaccharide
O23A_p1882	ENOG4105DSP	amino acid AbC transporter
O23A_p1883	ENOG4106PMH	Extracellular solute-binding protein family 3
O23A_p1884	ENOG4108JEH	abc transporter atp-binding protein
O23A_p1885	ENOG4105DWU	Membrane
O23A_p1886	ENOG4108ZYK	Acyl carrier protein phosphodiesterase
O23A_p1888	ENOG4105K89	arsenate reductase
O23A_p1890	ENOG4105ERG	peptidase m48, ste24p
O23A_p1891	ENOG41082K8	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Interacts with IscS and stimulates its activity. Then, accepts a sulfur from IscS and transfers it in turn to TusD (By similarity)
O23A_p1892	ENOG4105C02	permease
O23A_p1894	ENOG4105CSR	polyphosphate kinase 2
O23A_p1895	ENOG4108IJ9	(ABC) transporter
O23A_p1896	ENOG4105EG2	ABC transporter, permease
O23A_p1897	ENOG4105D56	permease protein
O23A_p1898	ENOG4107FKK	extracellular solute-binding protein family 1
O23A_p1899	ENOG4106V8H	Nucleoid-associated protein
O23A_p1900	ENOG4105PAN	UPF0352 protein
O23A_p1901	ENOG4105E68	Sulfatase
O23A_p1902	ENOG4105D05	Receptor
O23A_p1903	ENOG4105CUG	Oligopeptidase b
O23A_p1907	ENOG4108QSZ	General inhibitor of pancreatic serine proteases inhibits chymotrypsin, trypsin, elastases, factor X, kallikrein as well as a variety of other proteases (By similarity)
O23A_p1908	ENOG4108WFC	UPF0438 protein yifE
O23A_p1909	ENOG4105CVI	Transcriptional regulator
O23A_p1911	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
O23A_p1912	ENOG4106MZZ	glycerophosphoryl diester phosphodiesterase
O23A_p1913	ENOG4105C6V	Glycerol-3-phosphate dehydrogenase
O23A_p1914	ENOG4105E98	transcriptional regulator DeoR family
O23A_p1915	ENOG4105CXY	transporter
O23A_p1916	ENOG4105D8C	Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity)
O23A_p1917	ENOG4108JQ0	Key enzyme in the regulation of glycerol uptake and metabolism (By similarity)
O23A_p1918	ENOG4105HEI	LysR family (Transcriptional regulator
O23A_p1921	ENOG41067V3	Antibiotic biosynthesis monooxygenase
O23A_p1922	ENOG4105CV8	reductase
O23A_p1923	ENOG4105F27	Major Facilitator
O23A_p1926	ENOG4105E18	UPF0276 protein
O23A_p1930	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
O23A_p1931	ENOG4105C4M	(Ubiquinol oxidase) subunit I
O23A_p1932	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
O23A_p1934	ENOG4108Q2J	Inner membrane protein YebE
O23A_p1936	ENOG4106428	Protein of unknown function (DUF2496)
O23A_p1940	ENOG4105DJ2	Major Facilitator Superfamily
O23A_p1941	ENOG4105FE9	pseudouridine synthase
O23A_p1943	ENOG4105D82	Glutamate dehydrogenase
O23A_p1945	ENOG4105E2D	ec 3.2.1.52
O23A_p1948	ENOG4108R4U	Hnh endonuclease
O23A_p1952	ENOG4105DP5	Catalyzes the biosynthesis of agmatine from arginine (By similarity)
O23A_p1955	ENOG4105D42	Cleaves the N-terminal amino acid of tripeptides (By similarity)
O23A_p1960	ENOG4108YYC	ycei family
O23A_p1961	ENOG4105CC0	LysR family Transcriptional regulator
O23A_p1963	ENOG4105CKU	formyltetrahydrofolate synthetase
O23A_p1964	ENOG4105C8Q	Methyl-accepting chemotaxis
O23A_p1965	ENOG4105EUJ	GTP cyclohydrolase i
O23A_p1966	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
O23A_p1967	ENOG4105D06	uba thif-type nad fad binding protein
O23A_p1968	ENOG4105D3C	The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters (By similarity)
O23A_p1969	ENOG4105CGB	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system (By similarity)
O23A_p1970	ENOG4105E0C	molybdate abc transporter
O23A_p1971	ENOG4108S6J	ABC transporter, periplasmic molybdate-binding protein
O23A_p1972	ENOG4108ZAF	Molybdopterin
O23A_p1975	ENOG4105M00	molybdopterin converting factor, subunit 1
O23A_p1976	ENOG4108YXW	Together with MoaA, is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
O23A_p1977	ENOG4108RIR	Molybdenum cofactor biosynthesis protein
O23A_p1978	ENOG4105CUW	cytochrome C-TYPE protein
O23A_p1980	ENOG4105GXZ	Ferredoxin-type protein NapH
O23A_p1981	ENOG4108BGM	Quinol dehydrogenase periplasmic component
O23A_p1982	ENOG4107QIW	Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity)
O23A_p1985	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
O23A_p1986	ENOG4105BZU	Histidine kinase
O23A_p1987	ENOG4105WH1	Two component transcriptional regulator luxr family
O23A_p1990	ENOG4105BZU	Histidine kinase
O23A_p1992	ENOG4105CHW	UPF0052 protein
O23A_p1994	ENOG4105E7A	Glutamine amidotransferase
O23A_p1995	ENOG4105F55	Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate (By similarity)
O23A_p1996	ENOG4107QPN	acyl-Coa dehydrogenase
O23A_p1998	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
O23A_p2000	ENOG4108JDX	DNA polymerase iii, epsilon subunit
O23A_p2001	ENOG4108UMW	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
O23A_p2002	ENOG4105D1A	Methyltransferase
O23A_p2003	ENOG4108RW0	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
O23A_p2004	ENOG4105E9H	Lytic Murein transglycosylase
O23A_p2007	ENOG4105NAU	thioesterase Superfamily protein
O23A_p2009	ENOG41060NJ	transcriptional regulator
O23A_p2010	ENOG4107SC1	transglycosylase
O23A_p2011	ENOG4105BZU	Histidine kinase
O23A_p2013	ENOG4108WPH	sigma 54 modulation protein ribosomal protein S30EA
O23A_p2015	ENOG4105MA0	exported protein
O23A_p2016	ENOG4105CFU	surface antigen
O23A_p2021	ENOG4105KQ5	peptidylprolyl cis-trans isomerase
O23A_p2022	ENOG4107R50	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
O23A_p2024	ENOG4107ZN8	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity (By similarity)
O23A_p2025	ENOG4105DC8	reductase
O23A_p2026	ENOG4105VNH	ABC transporter solute-binding protein
O23A_p2027	ENOG4105CXZ	ABC transporter, permease
O23A_p2028	ENOG4108VGW	abc transporter atp-binding protein
O23A_p2029	ENOG4108T9J	Cdp-alcohol phosphatidyltransferase
O23A_p2030	ENOG4105CVE	Lytic murein transglycosylase
O23A_p2033	ENOG4107QIX	Phosphoglucomutase (EC 5.4.2.2
O23A_p2034	ENOG4107CDU	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated (By similarity)
O23A_p2035	ENOG4105EV9	Alpha Beta Hydrolase
O23A_p2037	ENOG4105NNH	LexA regulated protein
O23A_p2038	ENOG4105MHQ	Low-potential electron donor to a number of redox enzymes (By similarity)
O23A_p2040	ENOG41090R7	Ferric uptake
O23A_p2041	ENOG4105CX6	glutaminyL-tRNA synthetase
O23A_p2043	ENOG4105E2D	ec 3.2.1.52
O23A_p2044	ENOG4105CI1	PTS System
O23A_p2045	ENOG4105CKA	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion (By similarity)
O23A_p2046	ENOG4105CE4	GlcNAc 6-P deacetylase
O23A_p2047	ENOG4105E2R	ROK family
O23A_p2048	ENOG4105DIJ	Phosphoethanolamine transferase
O23A_p2049	ENOG4105CDY	transcriptional regulatory protein
O23A_p2050	ENOG4105C9M	aspartyl-trna synthetase
O23A_p2051	ENOG41081XQ	Conserved Protein
O23A_p2052	ENOG4105DA6	Catalyzes the conversion of 5-methoxyuridine (mo5U) to uridine-5-oxyacetic acid (cmo5U) at position 34 in tRNA. May also participate in the methylation of uridine-5-oxyacetic acid (cmo5U) to uridine-5-oxyacetic acid methyl ester (mcmo5U) (By similarity)
O23A_p2053	ENOG4105PFA	Catalyzes the conversion of 5-hydroxyuridine (ho5U) to 5-methoxyuridine (mo5U) at position 34 in tRNA (By similarity)
O23A_p2057	ENOG4105D3R	alkyl hydroperoxide reductase
O23A_p2058	ENOG4105C5Q	Transcriptional regulator
O23A_p2061	ENOG4108QBX	(LipO)protein
O23A_p2063	ENOG4107RGH	Aldehyde dehydrogenase
O23A_p2064	ENOG4107Z3H	Transcriptional regulator, TetR family
O23A_p2068	ENOG4105C6T	cysteine synthase
O23A_p2072	ENOG4105UQX	Mate efflux family protein
O23A_p2075	ENOG4105Z2P	Protein of unknown function (DUF465)
O23A_p2076	ENOG4105D95	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin (By similarity)
O23A_p2078	ENOG4105QVC	MOSC domain-containing protein
O23A_p2078	ENOG4105QVC	MOSC domain-containing protein
O23A_p2079	ENOG4107SDU	Methyl-accepting chemotaxis
O23A_p2080	ENOG4105D0M	Protease HtpX homolog
O23A_p2081	ENOG4105E78	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity)
O23A_p2082	ENOG410626R	Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity)
O23A_p2083	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
O23A_p2084	ENOG4105CZF	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism (By similarity)
O23A_p2085	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
O23A_p2088	ENOG4105C5S	asparaginyl-tRNA synthetase
O23A_p2089	ENOG4105DS2	Anaerobic c4-dicarboxylate transporter
O23A_p2094	ENOG4105KUZ	arsenate reductase
O23A_p2095	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
O23A_p2098	ENOG4105C3N	Participates in control of cell volume in low-osmolarity conditions (By similarity)
O23A_p2100	ENOG4105C3N	Participates in control of cell volume in low-osmolarity conditions (By similarity)
O23A_p2102	ENOG410829K	Lysine exporter protein (Lyse ygga)
O23A_p2103	ENOG4108N3W	hemolysin secretion protein
O23A_p2104	ENOG4105RX8	Protein of unknown function (DUF1523)
O23A_p2107	ENOG4105DU0	nucleoside hydrolase
O23A_p2108	ENOG4105D3G	Pseudouridine synthase
O23A_p2109	ENOG4107SXA	Phosphorylase
O23A_p2110	ENOG4105C0A	alcohol dehydrogenase
O23A_p2118	ENOG4107U53	septum site-determining protein minD
O23A_p2127	ENOG4105YRI	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
O23A_p2128	ENOG4105K4T	epimerase
O23A_p2129	ENOG4105VDB	UPF0125 protein
O23A_p2130	ENOG4108Z1B	Cyclase dehydrase
O23A_p2132	ENOG4108UH4	Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity)
O23A_p2138	ENOG41088T4	Helicase IV
O23A_p2141	ENOG4108JJA	ABC, transporter
O23A_p2146	ENOG4105BZU	Histidine kinase
O23A_p2148	ENOG4105DU6	RNA polymerase
O23A_p2150	ENOG4105E18	UPF0276 protein
O23A_p2153	ENOG4105BZU	Histidine kinase
O23A_p2154	ENOG4105BZU	Histidine kinase
O23A_p2156	ENOG4105CHH	sulfate transporter
O23A_p2181	ENOG4105W5Q	DNA repair protein (RadC
O23A_p2193	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
O23A_p2203	ENOG410890F	Dynamin family
O23A_p2209	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
O23A_p2212	ENOG4108HMX	isocitrate dehydrogenase (NADP)
O23A_p2213	ENOG4106R3P	AraC family transcriptional regulator
O23A_p2214	ENOG4105EIP	mannose-6-phosphate isomerase
O23A_p2216	ENOG4105DM4	PTS System
O23A_p2217	ENOG4105C87	Aminotransferase class I and II
O23A_p2218	ENOG4105CI1	PTS System
O23A_p2220	ENOG4107P2S	Transcriptional regulator
O23A_p2225	ENOG4107RDB	Major Facilitator
O23A_p2226	ENOG4105F1R	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group (By similarity)
O23A_p2227	ENOG41090KH	cytochrome o ubiquinol oxidase (subunit iv)
O23A_p2228	ENOG4105CCU	oxidase (Subunit III)
O23A_p2229	ENOG4105BZ9	Cytochrome C oxidase, subunit I
O23A_p2230	ENOG4105E2S	oxidase) subunit II
O23A_p2242	ENOG4105CGK	Exodeoxyribonuclease III
O23A_p2248	ENOG4105EP1	Efflux transporter rnd family, mfp subunit
O23A_p2249	ENOG4108IJF	Heavy metal efflux pump, CzcA
O23A_p2251	ENOG4107RMF	Catalyzes both the ATP-dependent activation of exogenously supplied lipoate to lipoyl-AMP and the transfer of the activated lipoyl onto the lipoyl domains of lipoate-dependent enzymes (By similarity)
O23A_p2252	ENOG4105BZU	Histidine kinase
O23A_p2257	ENOG41080HT	Transcriptional regulator, arsr family
O23A_p2261	ENOG4105WBN	Transcriptional regulator (LacI family
O23A_p2262	ENOG4108HKT	sucrose-6-phosphate hydrolase
O23A_p2264	ENOG4105D7K	pfkb domain protein
O23A_p2267	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
O23A_p2268	ENOG4105CFG	Acts as a chaperone (By similarity)
O23A_p2269	ENOG4105K90	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
O23A_p2270	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
O23A_p2271	ENOG4105C4F	May be involved in recombinational repair of damaged DNA (By similarity)
O23A_p2272	ENOG4105E2M	Manganese-dependent inorganic pyrophosphatase
O23A_p2274	ENOG4105DJY	efflux transporter, rnd family, mfp subunit
O23A_p2275	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
O23A_p2276	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
O23A_p2277	ENOG4105Q26	Siderophore-interacting protein
O23A_p2284	ENOG4105CJP	fad dependent oxidoreductase
O23A_p2285	ENOG4107VRI	Transcriptional regulator
O23A_p2286	ENOG4105C26	Dehydrogenase
O23A_p2287	ENOG4108JPW	Aminotransferase
O23A_p2288	ENOG4105CUB	amino acid
O23A_p2290	ENOG4105CUB	amino acid
O23A_p2292	ENOG4108V1T	peptidylprolyl cis-trans isomerase
O23A_p2293	ENOG4105C8E	extradiol ring-cleavage dioxygenase class IIi protein subunit b
O23A_p2297	ENOG4108QW8	Purine nucleoside phosphorylase deoD-type
O23A_p2302	ENOG4105D98	threonine synthase
O23A_p2303	ENOG4105D5I	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate (By similarity)
O23A_p2305	ENOG4106FVC	RNA methyltransferase
O23A_p2307	ENOG4105VS7	Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue. This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon. When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation (By similarity)
O23A_p2311	ENOG4108YYX	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. Modulates RNA-binding and helicase activities of the degradosome (By similarity)
O23A_p2314	ENOG41065U4	response regulator
O23A_p2315	ENOG4108JJ9	ABC, transporter
O23A_p2316	ENOG4108JJ8	(ABC) transporter
O23A_p2320	ENOG4108R96	Methyltransferase, YaeB family
O23A_p2324	ENOG4105C6T	cysteine synthase
O23A_p2325	ENOG4105KZ7	phosphocarrier protein hpr
O23A_p2327	ENOG4105C5Y	PTS System
O23A_p2328	ENOG4105BZU	Histidine kinase
O23A_p2330	ENOG4105CPW	cytochrome b561
O23A_p2332	ENOG4105EYH	Exonuclease
O23A_p2333	ENOG4107RH8	nuclease SbcCD subunit D
O23A_p2335	ENOG4105DH7	May be involved in recombination (By similarity)
O23A_p2336	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
O23A_p2338	ENOG4105CKD	glutathione-regulated potassium-efflux system protein
O23A_p2341	ENOG4105CA9	Pyruvate kinase
O23A_p2342	ENOG4105EGS	Mechanosensitive ion channel
O23A_p2346	ENOG4106TNF	Periplasmic binding protein
O23A_p2348	ENOG4105C2W	permease
O23A_p2351	ENOG4107R1I	NAD-dependent malic enzyme
O23A_p2354	ENOG4105QAX	Iron-sulfur
O23A_p2355	ENOG4108IEG	Formate dehydrogenase Alpha subunit
O23A_p2355	ENOG4108IEG	Formate dehydrogenase Alpha subunit
O23A_p2363	ENOG4107H9G	Necessary for formate dehydrogenase activity (By similarity)
O23A_p2365	ENOG4105BZU	Histidine kinase
O23A_p2366	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
O23A_p2369	ENOG4107A5B	Binding-protein-dependent transport systems, inner membrane component
O23A_p2370	ENOG4108IUZ	ABC transporter
O23A_p2371	ENOG4105C6R	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor (By similarity)
O23A_p2372	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
O23A_p2373	ENOG4105DR8	Membrane
O23A_p2374	ENOG4108ESY	Metal dependent phosphohydrolase
O23A_p2375	ENOG4107SDU	Methyl-accepting chemotaxis
O23A_p2377	ENOG4105XIQ	Protein of unknown function (DUF2517)
O23A_p2379	ENOG4105BZU	Histidine kinase
O23A_p2382	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
O23A_p2383	ENOG4105C3U	ABC transporter
O23A_p2384	ENOG4108JQ7	(ABC) transporter
O23A_p2386	ENOG4105RD7	BadF BadG BcrA BcrD
O23A_p2388	ENOG4105E2D	ec 3.2.1.52
O23A_p2389	ENOG4107RHT	methyl-accepting chemotaxis sensory transducer with Pas Pac sensor
O23A_p2392	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
O23A_p2393	ENOG4105EY2	Catalyzes the hydrolysis of N(2)-succinylarginine into N(2)-succinylornithine, ammonia and CO(2) (By similarity)
O23A_p2394	ENOG4105ERU	peptidase
O23A_p2395	ENOG4105UBK	short-chain dehydrogenase reductase
O23A_p2396	ENOG4105C5Q	Transcriptional regulator
O23A_p2399	ENOG4105C87	Aminotransferase class I and II
O23A_p2402	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
O23A_p2403	ENOG4108V1U	phospholipid-binding protein
O23A_p2405	ENOG4107T9C	Alpha amylase catalytic region
O23A_p2413	ENOG4105BZU	Histidine kinase
O23A_p2414	ENOG4105D3U	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
O23A_p2415	ENOG4105C9K	Endothelin-converting enzyme 1
O23A_p2417	ENOG4105C5H	ABC transporter
O23A_p2418	ENOG4105KNA	-acetyltransferase
O23A_p2419	ENOG4105DVH	amino acid
O23A_p2420	ENOG4105C44	Serine transporter
O23A_p2421	ENOG4105EQ2	LysR family Transcriptional regulator
O23A_p2423	ENOG4107XGF	functions in a salvage pathway. Uses pyridoxamine (By similarity)
O23A_p2424	ENOG4105CXN	decarboxylase
O23A_p2425	ENOG4105D5Q	Arginine ornithine antiporter
O23A_p2426	ENOG4108M3R	transcriptional activator CadC
O23A_p2427	ENOG4107QM9	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA (By similarity)
O23A_p2428	ENOG4105C0B	DNA polymerase III (alpha subunit)
O23A_p2429	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
O23A_p2430	ENOG4105D0V	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
O23A_p2431	ENOG4105DAF	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
O23A_p2432	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
O23A_p2433	ENOG4105D7M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
O23A_p2434	ENOG4108RFI	Molecular chaperone that interacts specifically with outer membrane proteins, thus maintaining the solubility of early folding intermediates during passage through the periplasm (By similarity)
O23A_p2436	ENOG4105DZP	Membrane-associated zinc metalloprotease
O23A_p2438	ENOG4105CEA	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity)
O23A_p2439	ENOG4105KNE	Phosphatidate cytidylyltransferase
O23A_p2440	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
O23A_p2441	ENOG4108VCV	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity)
O23A_p2442	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
O23A_p2443	ENOG4105CU7	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity)
O23A_p2444	ENOG4105CE9	30S ribosomal protein S2
O23A_p2446	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
O23A_p2447	ENOG4105E1P	Modifies, by uridylylation or deuridylylation the PII (GlnB) regulatory protein (By similarity)
O23A_p2448	ENOG4105DMJ	Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate (By similarity)
O23A_p2449	ENOG4108T8E	UPF0325 protein
O23A_p2450	ENOG4105CI1	PTS System
O23A_p2451	ENOG4107W52	maltose operon periplasmic protein
O23A_p2452	ENOG4108KDD	Involved in the transport of maltose and maltodextrins (By similarity)
O23A_p2453	ENOG4105QDK	Flavodoxin
O23A_p2454	ENOG4105DR9	pseudouridine synthase
O23A_p2455	ENOG4105WP7	tRNA pseudouridine synthase C
O23A_p2460	ENOG4105EXF	Zn-ribbon-containing, possibly nucleic-acid-binding protein
O23A_p2461	ENOG4108T6E	Interacts with the SecY protein in vivo. May bind preferentially to an uncomplexed state of SecY, thus functioning either as a chelating agent for excess SecY in the cell or as a regulatory factor that negatively controls the translocase function (By similarity)
O23A_p2463	ENOG4107R1K	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) (By similarity)
O23A_p2466	ENOG4105BZU	Histidine kinase
O23A_p2467	ENOG4105EWT	decarboxylase family
O23A_p2468	ENOG4105CIQ	May have a role in processing of nucleic acids. It is probably not an exonuclease
O23A_p2469	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
O23A_p2471	ENOG4105EZ6	Catalyzes the 2'-O-methylation at nucleotide C2498 in 23S rRNA (By similarity)
O23A_p2472	ENOG4105M08	Membrane
O23A_p2474	ENOG4105ETT	transcriptional Regulator, LysR family
O23A_p2475	ENOG4105C8Q	Methyl-accepting chemotaxis
O23A_p2476	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
O23A_p2479	ENOG4105CJ2	(LipO)protein
O23A_p2480	ENOG4105D26	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. The first step is catalyzed by NqrF, which accepts electrons from NADH and reduces ubiquinone-1 to ubisemiquinone by a one-electron transfer pathway (By similarity)
O23A_p2481	ENOG4108IUB	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
O23A_p2482	ENOG4105F5D	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
O23A_p2483	ENOG4106I92	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
O23A_p2484	ENOG4108J5C	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
O23A_p2485	ENOG4105DWQ	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
O23A_p2486	ENOG4105M85	Bola protein
O23A_p2487	ENOG4105D8J	Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle (By similarity)
O23A_p2489	ENOG4108R5K	PPIases accelerate the folding of proteins (By similarity)
O23A_p2491	ENOG4105EYM	Major Facilitator superfamily
O23A_p2492	ENOG4105DRB	nucleoside-specific channel-forming protein
O23A_p2493	ENOG4108VPT	UPF0234 protein
O23A_p2494	ENOG4108JZF	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity)
O23A_p2495	ENOG4107S0N	DJ-1 family
O23A_p2496	ENOG4105C7K	acetolactate synthase
O23A_p2499	ENOG4105E2V	Glycosyltransferase 36
O23A_p2505	ENOG4105CS6	Rhs element vgr protein
O23A_p2507	ENOG4108WC9	type VI secretion system effector, hcp1 family
O23A_p2508	ENOG4105VJY	transcriptional regulator
O23A_p2509	ENOG4105DRC	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity)
O23A_p2510	ENOG4105CMR	udp-glucose 4-epimerase
O23A_p2512	ENOG4105EJ7	Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O (By similarity)
O23A_p2513	ENOG4108RMU	ferritin dps family protein
O23A_p2518	ENOG4105CV9	cyclopropane-fatty-acyl-phospholipid synthase
O23A_p2522	ENOG4107FW0	short-chain dehydrogenase reductase
O23A_p2524	ENOG4105CVP	deoxyribo-dipyrimidine photolyase
O23A_p2525	ENOG4108XDN	Transcriptional regulator
O23A_p2526	ENOG4107SEY	Conserved Protein
O23A_p2533	ENOG4105CQC	Prephenate dehydratase
O23A_p2539	ENOG4105MVE	transcriptional regulator
O23A_p2541	ENOG4105G63	Type III effector Hrp-dependent
O23A_p2543	ENOG4105QG4	Catalyzes the reversible isomerization between hydroxypyruvate and 2-hydroxy-3-oxopropanoate (also termed tartronate semialdehyde) (By similarity)
O23A_p2544	ENOG4105EXW	epimerase dehydratase
O23A_p2545	ENOG4105C6Z	Gluconate
O23A_p2547	ENOG4105EC8	Methyl-accepting chemotaxis
O23A_p2549	ENOG4105J5J	Outer membrane porin
O23A_p2550	ENOG4105E1F	short-chain dehydrogenase reductase
O23A_p2555	ENOG4105CTD	carboxy-peptidase
O23A_p2558	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
O23A_p2560	ENOG4105XDF	Protein of unknown function (DUF1272)
O23A_p2562	ENOG4105CFP	Peptidase U32
O23A_p2563	ENOG4105N14	lysine exporter protein LysE YggA
O23A_p2565	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
O23A_p2566	ENOG4105C8Q	Methyl-accepting chemotaxis
O23A_p2567	ENOG4108VYJ	response regulator receiver protein
O23A_p2569	ENOG4105CBS	Chea signal transduction histidine kinase
O23A_p2571	ENOG4108V3W	Chemotaxis protein, CheW
O23A_p2572	ENOG4105C8Q	Methyl-accepting chemotaxis
O23A_p2573	ENOG4105BZU	Histidine kinase
O23A_p2574	ENOG4108Z4W	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis (By similarity)
O23A_p2575	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
O23A_p2576	ENOG4105C9B	Cysteine desulfurase
O23A_p2579	ENOG4105BZU	Histidine kinase
O23A_p2580	ENOG41068CG	regulatoR
O23A_p2583	ENOG4108N3D	putative enzyme
O23A_p2586	ENOG4108NJZ	Sensory box GGDEF EAL domain protein
O23A_p2592	ENOG4105EQR	Transposase IS116 IS110 IS902
O23A_p2607	ENOG4105CHH	sulfate transporter
O23A_p2608	ENOG4105F2I	Transposase
O23A_p2609	ENOG4105F2I	Transposase
O23A_p2611	ENOG4105EC0	Required for nucleoid occlusion (NO) phenomenon, which prevents Z-ring formation and cell division over the nucleoid. Acts as a DNA-associated cell division inhibitor that binds simultaneously chromosomal DNA and FtsZ, and disrupts the assembly of FtsZ polymers. SlmA-DNA-binding sequences (SBS) are dispersed on non-Ter regions of the chromosome, preventing FtsZ polymerization at these regions (By similarity)
O23A_p2614	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
O23A_p2622	ENOG4108YX2	DNA-binding protein
O23A_p2629	ENOG4105DFG	type I secretion outer membrane protein
O23A_p2630	ENOG4108IJF	Heavy metal efflux pump, CzcA
O23A_p2633	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
O23A_p2634	ENOG4105GR3	Histidine kinase
O23A_p2640	ENOG4105E3B	Multicopper oxidase
O23A_p2642	ENOG4105F2I	Transposase
O23A_p2644	ENOG4105KT5	UmuD protein
O23A_p2645	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
O23A_p2647	ENOG4105CFP	Peptidase U32
O23A_p2648	ENOG4105K5D	4fe-4S ferredoxin iroN-sulfur binding
O23A_p2649	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
O23A_p2650	ENOG4105CDU	Replicative dna helicase
O23A_p2656	ENOG4105CGH	5'-nucleotidase
O23A_p2660	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
O23A_p2661	ENOG4108V1T	peptidylprolyl cis-trans isomerase
O23A_p2663	ENOG4105VRX	Protein slyX homolog
O23A_p2664	ENOG4108YZY	peptidylprolyl cis-trans isomerase
O23A_p2665	ENOG4105VKU	nucleicacid-binding protein
O23A_p2667	ENOG4107R88	Chemotaxis protein (CheV)
O23A_p2668	ENOG4105DNZ	Alpha Beta Hydrolase
O23A_p2670	ENOG4105YP7	UPF0270 protein
O23A_p2672	ENOG4105C6Y	Udp-glucose 6-dehydrogenase
O23A_p2674	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
O23A_p2675	ENOG4105CKK	Glycosyl transferase, family 2
O23A_p2676	ENOG4105C3I	Nad-dependent epimerase dehydratase
O23A_p2677	ENOG4105F73	Catalyzes the deformylation of 4-deoxy-4-formamido-L- arabinose-phosphoundecaprenol to 4-amino-4-deoxy-L-arabinose- phosphoundecaprenol. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides (By similarity)
O23A_p2678	ENOG4105SA9	Catalyzes the transfer of the L-Ara4N moiety of the glycolipid undecaprenyl phosphate-alpha-L-Ara4N to lipid A. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides (By similarity)
O23A_p2679	ENOG41060GT	Translocates 4-amino-4-deoxy-L-arabinose- phosphoundecaprenol (alpha-L-Ara4N-phosphoundecaprenol) from the cytoplasmic to the periplasmic side of the inner membrane (By similarity)
O23A_p2680	ENOG4105PE8	Translocates 4-amino-4-deoxy-L-arabinose- phosphoundecaprenol (alpha-L-Ara4N-phosphoundecaprenol) from the cytoplasmic to the periplasmic side of the inner membrane (By similarity)
O23A_p2681	ENOG4105CJE	phosphoribulokinase (EC 2.7.1.19)
O23A_p2684	ENOG4108UKZ	OsmC family
O23A_p2685	ENOG4107RYR	Transcriptional regulator, Crp Fnr family
O23A_p2686	ENOG4105DHI	Methyltransferase
O23A_p2687	ENOG4108M1A	Chitin-binding protein
O23A_p2688	ENOG4108MA4	Peptidase M66
O23A_p2690	ENOG4105BZU	Histidine kinase
O23A_p2692	ENOG4105VMP	Transcriptional regulator
O23A_p2694	ENOG4105D8G	Major Facilitator superfamily
O23A_p2696	ENOG4105D05	Receptor
O23A_p2700	ENOG4105PYN	Pyridoxamine 5-phosphate oxidase-related
O23A_p2701	ENOG41090JE	Utilization Protein
O23A_p2703	ENOG4105EHG	Permease protein
O23A_p2704	ENOG4108IPX	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system (By similarity)
O23A_p2709	ENOG4105E4C	Lytic transglycosylase catalytic
O23A_p2710	ENOG4105C5H	ABC transporter
O23A_p2712	ENOG4105C7N	Xanthine uracil vitamin C permease
O23A_p2713	ENOG41066UG	Regulatory DnaK co-chaperone. Direct interaction between DnaK and DjlA is needed for the induction of the wcaABCDE operon, involved in the synthesis of a colanic acid polysaccharide capsule, possibly through activation of the RcsB RcsC phosphotransfer signaling pathway. The colanic acid capsule may help the bacterium survive conditions outside the host (By similarity)
O23A_p2714	ENOG4108S0S	Nucleotidyl transferase
O23A_p2715	ENOG4105EHM	Aminoglycoside phosphotransferase
O23A_p2716	ENOG4105E7H	involved in the assembly of LPS in the outer leaflet of the outer membrane. Determines N-hexane tolerance and is involved in outer membrane permeability. Essential for envelope biogenesis (By similarity)
O23A_p2718	ENOG4105CEZ	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) (By similarity)
O23A_p2719	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
O23A_p2720	ENOG4105NWN	ApaG protein
O23A_p2721	ENOG4105DDT	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP (By similarity)
O23A_p2724	ENOG4105DEN	Luciferase family
O23A_p2726	ENOG4108ESY	Metal dependent phosphohydrolase
O23A_p2728	ENOG4105CEY	Amp-dependent synthetase and ligase
O23A_p2729	ENOG4105DWD	nucleoside recognition domain protein
O23A_p2730	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
O23A_p2731	ENOG4105K46	50S ribosomal protein l27
O23A_p2732	ENOG4105KK9	This protein binds to 23S rRNA in the presence of protein L20 (By similarity)
O23A_p2733	ENOG4105EAH	synthase
O23A_p2735	ENOG4105EPW	hflc protein
O23A_p2736	ENOG4107QJR	hflk protein
O23A_p2737	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
O23A_p2738	ENOG4105KW8	RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity)
O23A_p2739	ENOG4105DKX	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity)
O23A_p2740	ENOG4105DC6	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity)
O23A_p2742	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
O23A_p2743	ENOG4105K8N	protein family UPF0079, ATPase
O23A_p2744	ENOG4105DR1	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)
O23A_p2750	ENOG4108UMI	ABC transporter, permease
O23A_p2751	ENOG4105D01	(LipO)protein
O23A_p2752	ENOG4105MDZ	Transcriptional activator rfaH
O23A_p2755	ENOG4108N3W	hemolysin secretion protein
O23A_p2756	ENOG4105BZU	Histidine kinase
O23A_p2757	ENOG4105BZU	Histidine kinase
O23A_p2759	ENOG4105C4Q	deoxyguanosinetriphosphate triphosphohydrolase-like protein
O23A_p2760	ENOG4105BZU	Histidine kinase
O23A_p2765	ENOG4105EXG	Transcriptional regulator
O23A_p2767	ENOG4107QWK	SAICAR synthetase
O23A_p2768	ENOG4107EG0	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
O23A_p2769	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
O23A_p2770	ENOG4105RH4	Glycine cleavage system transcriptional repressor
O23A_p2771	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
O23A_p2772	ENOG4105XWI	UPF0304 protein
O23A_p2773	ENOG4105PQ6	UPF0208 membrane protein
O23A_p2774	ENOG4105C6H	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity)
O23A_p2775	ENOG4105C6K	Malic enzyme
O23A_p2776	ENOG4108ZP8	Acetolactate synthase small subunit
O23A_p2777	ENOG4105C7K	acetolactate synthase
O23A_p2781	ENOG4105YVM	Phosphoesterase, PA-phosphatase related
O23A_p2783	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
O23A_p2785	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
O23A_p2786	ENOG4105MQS	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
O23A_p2789	ENOG4105DP9	ABC transporter
O23A_p2790	ENOG4106SMU	thiamine transporter membrane protein
O23A_p2791	ENOG4107T0D	ABC, transporter
O23A_p2793	ENOG4108IAB	Phoh family
O23A_p2795	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
O23A_p2798	ENOG4108YX9	iron--sulfur cluster insertion protein erpA
O23A_p2800	ENOG4105CMQ	Chloride channel
O23A_p2801	ENOG4105CDM	Glutamate-1-semialdehyde aminotransferase
O23A_p2806	ENOG41076MN	Phosphoesterase, PA-phosphatase related
O23A_p2808	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
O23A_p2809	ENOG4105CWB	LysR family transcriptional Regulator
O23A_p2810	ENOG41090TI	Catalyzes the excretion of spermidine (By similarity)
O23A_p2811	ENOG4108ZBZ	Catalyzes the excretion of spermidine (By similarity)
O23A_p2812	ENOG4108YZK	glyoxalase bleomycin resistance protein dioxygenase
O23A_p2813	ENOG4105BZ4	penicillin-binding protein
O23A_p2814	ENOG4105CQ7	ATP-dependent helicase
O23A_p2816	ENOG4105PW4	Sugar fermentation stimulation protein homolog
O23A_p2817	ENOG4108V7X	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
O23A_p2818	ENOG4106F3G	Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon (By similarity)
O23A_p2819	ENOG4105DJ0	Poly(A) Polymerase
O23A_p2820	ENOG4105K8U	2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
O23A_p2821	ENOG4105CCG	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is tranferred onto alpha-ketoisovalerate to form ketopantoate (By similarity)
O23A_p2822	ENOG4108IAA	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate (By similarity)
O23A_p2824	ENOG4105E3A	(ABC) transporter
O23A_p2825	ENOG4105DA5	(ABC) transporter
O23A_p2826	ENOG4108UGV	hypoxanthine phosphoribosyltransferase
O23A_p2827	ENOG410630P	Transcriptional regulator
O23A_p2828	ENOG4108UMA	3-octaprenyl-4-hydroxybenzoate carboxy-lyase
O23A_p2829	ENOG4105DFU	Cell wall formation (By similarity)
O23A_p2830	ENOG4105F0N	pyrophosphate phospho-hydrolase
O23A_p2831	ENOG4105CFZ	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III (By similarity)
O23A_p2832	ENOG4105E09	nadh pyrophosphatase
O23A_p2833	ENOG4105C26	Dehydrogenase
O23A_p2834	ENOG4106MWK	domain protein
O23A_p2835	ENOG4105EYW	Ion transport protein
O23A_p2836	ENOG4105C8Q	Methyl-accepting chemotaxis
O23A_p2837	ENOG4105E0X	reductase
O23A_p2839	ENOG4105C9C	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity)
O23A_p2840	ENOG4107RTM	4-alpha-glucanotransferase (EC 2.4.1.25)
O23A_p2842	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
O23A_p2843	ENOG4105DSB	aldose 1-epimerase
O23A_p2844	ENOG4105D0I	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate (By similarity)
O23A_p2845	ENOG4105C8Q	Methyl-accepting chemotaxis
O23A_p2846	ENOG4105UFD	tol-pal system protein YbgF
O23A_p2847	ENOG4105KCK	Peptidoglycan-associated lipoprotein
O23A_p2848	ENOG4107R6Y	Involved in the TonB-independent uptake of proteins (By similarity)
O23A_p2850	ENOG4105M8F	Biopolymer transport protein exbD tolR
O23A_p2851	ENOG4105E02	MotA TolQ exbB proton channel
O23A_p2852	ENOG4107YD3	Thioesterase
O23A_p2853	ENOG4105KJB	cyd operon protein YbgE
O23A_p2855	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
O23A_p2856	ENOG4105C4M	(Ubiquinol oxidase) subunit I
O23A_p2858	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
O23A_p2859	ENOG4105KA4	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity)
O23A_p2860	ENOG4105C8Q	Methyl-accepting chemotaxis
O23A_p2861	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
O23A_p2863	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
O23A_p2864	ENOG4108MJ3	acetyltransferase
O23A_p2865	ENOG4105KD7	acetyltransferase
O23A_p2867	ENOG4105C8A	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP (By similarity)
O23A_p2868	ENOG4105BZU	Histidine kinase
O23A_p2869	ENOG4105BZU	Histidine kinase
O23A_p2870	ENOG4105EW9	transcriptional regulator AsnC family
O23A_p2871	ENOG4105EV2	VWA domain protein interacting with AAA ATPase
O23A_p2872	ENOG4107R4Q	Functions as an ATPase. May play a role in metal insertion (metal-chelatase) or as a chaperone (By similarity)
O23A_p2875	ENOG4108RTV	Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol (By similarity)
O23A_p2877	ENOG4108IQE	Amp-dependent synthetase and ligase
O23A_p2879	ENOG4105D9M	gamma-glutamylcysteine synthetase
O23A_p2881	ENOG4105W39	Membrane
O23A_p2882	ENOG4105DQ4	alcohol dehydrogenase
O23A_p2887	ENOG4105DP0	ferredoxin-NADP reductase
O23A_p2888	ENOG4105K9Q	Binds to the 23S rRNA (By similarity)
O23A_p2889	ENOG4105VH8	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity)
O23A_p2890	ENOG4108ZDX	Binds together with S18 to 16S ribosomal RNA (By similarity)
O23A_p2891	ENOG4105C56	H( )-stimulated, divalent metal cation uptake system (By similarity)
O23A_p2892	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
O23A_p2897	ENOG4105C2N	RNA methyltransferase TrmH family group 3
O23A_p2898	ENOG4105C40	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity)
O23A_p2899	ENOG4106TD9	Diguanylate cyclase
O23A_p2900	ENOG4106762	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD) (By similarity)
O23A_p2902	ENOG4108YZA	Nitrogen regulatory protein pii
O23A_p2903	ENOG4105C4K	Nad synthetase
O23A_p2911	ENOG4106855	Competence protein
O23A_p2916	ENOG4105C48	Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) (By similarity)
O23A_p2917	ENOG41090X3	Peptidyl-prolyl cis-trans isomerase
O23A_p2918	ENOG4105M02	This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity)
O23A_p2919	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
O23A_p2920	ENOG4105DTN	riboflavin biosynthesis protein ribF
O23A_p2921	ENOG4105CJR	Integral membrane protein (MviN
O23A_p2922	ENOG4105KQV	Binds directly to 16S ribosomal RNA (By similarity)
O23A_p2923	ENOG41080HT	Transcriptional regulator, arsr family
O23A_p2924	ENOG41063Z6	transcriptional regulator, lysR family
O23A_p2926	ENOG4105DRC	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity)
O23A_p2927	ENOG4105C0V	Provides the sole de novo source of dTMP for DNA biosynthesis (By similarity)
O23A_p2936	ENOG4105CHH	sulfate transporter
O23A_p2943	ENOG4105K89	arsenate reductase
O23A_p2944	ENOG4105D6J	arsenicaL-resistance protein
O23A_p2946	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
O23A_p2948	ENOG4107WAU	Protein tyrosine phosphatase
O23A_p2951	ENOG4108UXE	Protein tyrosine phosphatase
O23A_p2952	ENOG41085FC	arsR family transcriptional regulator
O23A_p2956	ENOG4105D3S	4Fe-4S Ferredoxin, iron-sulfur binding domain protein
O23A_p2957	ENOG4105C3J	Cysteine desulfurase
O23A_p2958	ENOG4105C0V	Provides the sole de novo source of dTMP for DNA biosynthesis (By similarity)
O23A_p2962	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
O23A_p2963	ENOG4105C0V	Provides the sole de novo source of dTMP for DNA biosynthesis (By similarity)
O23A_p2964	ENOG4105C3B	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity)
O23A_p2965	ENOG4108HRM	phosphoenolpyruvate--protein phosphotransferase
O23A_p2966	ENOG4105EJF	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity)
O23A_p2969	ENOG4105IRT	Sequence-specific endonuclease that cleaves unmethylated GATC sequences. It is involved in DNA mismatch repair (By similarity)
O23A_p2971	ENOG4108YY1	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity)
O23A_p2972	ENOG4105D6X	Specifically methylates guanosine-37 in various tRNAs (By similarity)
O23A_p2973	ENOG4108ZR6	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity)
O23A_p2974	ENOG4105K5M	30s ribosomal protein S16
O23A_p2976	ENOG4105CB9	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
O23A_p2977	ENOG4106KVJ	cytochrome C assembly protein
O23A_p2978	ENOG4108JU6	CBS domain protein
O23A_p2979	ENOG4105KPV	Transcriptional regulator
O23A_p2980	ENOG4108EGH	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity)
O23A_p2981	ENOG4108UV7	flagellar protein motX
O23A_p2982	ENOG4105C80	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
O23A_p2983	ENOG4105DMR	ABC, transporter
O23A_p2986	ENOG4105GBT	ABC transporter
O23A_p2987	ENOG4106PMH	Extracellular solute-binding protein family 3
O23A_p2988	ENOG4105E5Z	arginine transporter ATP-binding subunit
O23A_p2989	ENOG410682Y	Regulates arginine biosynthesis genes (By similarity)
O23A_p2990	ENOG4105EZR	dyp-type peroxidase family protein
O23A_p2991	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
O23A_p2994	ENOG4108YZA	Nitrogen regulatory protein pii
O23A_p2995	ENOG4108YZN	class I peptide chain release factor
O23A_p2997	ENOG4105D9N	nucleoside
O23A_p2998	ENOG4105JQN	Transcriptional regulator
O23A_p3001	ENOG4105BZW	Glycerate kinase
O23A_p3002	ENOG4107QQ0	gntp family
O23A_p3003	ENOG4108IXP	Carbohydrate diacid transcriptional activator CdaR
O23A_p3004	ENOG4105XTV	UPF0231 protein
O23A_p3007	ENOG4107RHT	methyl-accepting chemotaxis sensory transducer with Pas Pac sensor
O23A_p3008	ENOG4108QYW	Bacterial hemolysins are exotoxins that attack blood cell membranes and cause cell rupture. Beta-hemolysin is a phospholipase C with specific activity toward sphingomyelins. Has a high specificity for sphingomyelin, hydrolyzes lysophosphatidylcholine at a much lower rate, but has no activity towards phosphatidylcholine, phosphatidylethanolamine, or phosphatidylserine (By similarity)
O23A_p3011	ENOG4105C1J	atp-dependent rna helicase
O23A_p3013	ENOG4108V1J	Has antioxidant activity. Could remove peroxides or H(2)O(2) (By similarity)
O23A_p3019	ENOG4105CGF	Aromatic amino acid aminotransferase
O23A_p3023	ENOG41076CZ	activating enzyme
O23A_p3024	ENOG4105G0K	glycine radical enzyme YjjI family
O23A_p3028	ENOG4107RE3	peptidase, S41
O23A_p3031	ENOG4105CND	Glycosyl transferase, family 2
O23A_p3032	ENOG4107BJW	polysaccharide deacetylase
O23A_p3041	ENOG4108M1A	Chitin-binding protein
O23A_p3042	ENOG4105CT1	(ABC) transporter
O23A_p3043	ENOG4105CDA	abc transporter atp-binding protein
O23A_p3045	ENOG4105E5Q	amino acid AbC transporter
O23A_p3046	ENOG4108IYI	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine (By similarity)
O23A_p3047	ENOG4107R11	Transcriptional regulator
O23A_p3048	ENOG4108IJ6	ABC transporter
O23A_p3049	ENOG4105ECW	sulfate abc transporter
O23A_p3050	ENOG4108I5D	sulfate abc transporter
O23A_p3052	ENOG4105DE7	Sulfate ABC transporter periplasmic sulfate-binding protein
O23A_p3053	ENOG4107PU6	Membrane
O23A_p3054	ENOG4108UW5	maltose o-acetyltransferase
O23A_p3060	ENOG41090U3	tautomerase
O23A_p3062	ENOG4107NQ8	LysR family Transcriptional regulator
O23A_p3063	ENOG4105CH7	arginosuccinase
O23A_p3064	ENOG4105CDH	Citrulline--aspartate ligase
O23A_p3066	ENOG4105CAS	nag kinase
O23A_p3067	ENOG4105C0N	N-acetylglutamate semialdehyde dehydrogenase
O23A_p3069	ENOG4105CCA	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle (By similarity)
O23A_p3071	ENOG4105H3G	oxidoreductase
O23A_p3072	ENOG4105K89	arsenate reductase
O23A_p3073	ENOG4105D6J	arsenicaL-resistance protein
O23A_p3076	ENOG41085FC	arsR family transcriptional regulator
O23A_p3077	ENOG4105D86	that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity)
O23A_p3081	ENOG4105R2J	Conserved Protein
O23A_p3083	ENOG4105DR5	peptidase
O23A_p3087	ENOG4105NXV	High-affinity zinc uptake system protein
O23A_p3088	ENOG4105FDK	ABC transporter
O23A_p3089	ENOG4105FAV	ABC, transporter
O23A_p3090	ENOG4105ETT	transcriptional Regulator, LysR family
O23A_p3092	ENOG4108RG0	uracil-dna glycosylase
O23A_p3093	ENOG4105FR1	rard protein
O23A_p3095	ENOG41082IR	Excinuclease ABC C subunit domain protein
O23A_p3098	ENOG41087YS	Phage shock protein A
O23A_p3099	ENOG4107S7E	1-acyl-sn-glycerol-3-phosphate acyltransferase
O23A_p3106	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
O23A_p3115	ENOG4105CBN	LysR family transcriptional regulator
O23A_p3117	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
O23A_p3118	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
O23A_p3122	ENOG4105IPS	esterase
O23A_p3123	ENOG41070EG	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes (By similarity)
O23A_p3124	ENOG4108SX3	cytoplasmic protein
O23A_p3125	ENOG41087AY	ADP-Ribose pyrophosphatase
O23A_p3126	ENOG4105DFG	type I secretion outer membrane protein
O23A_p3128	ENOG4105DW0	Catalyzes the ADP transfer to D-glycero-D-manno-heptose 1-phosphate, yielding ADP-D,D-heptose (By similarity)
O23A_p3129	ENOG4105D1S	lipid A biosynthesis
O23A_p3133	ENOG4107IX6	phosphate transport regulator
O23A_p3134	ENOG4105CJ3	phosphate transporter
O23A_p3135	ENOG4105D4J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
O23A_p3138	ENOG4105CEN	a g-specific adenine glycosylase
O23A_p3139	ENOG4105KMG	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes (By similarity)
O23A_p3141	ENOG4105H4F	exported protein
O23A_p3144	ENOG4105UYK	outer membrane protein a
O23A_p3145	ENOG4108Q2G	(LipO)protein
O23A_p3146	ENOG4105DY2	Paraquat-inducible protein b
O23A_p3147	ENOG4105F1S	paraquat-inducible protein a
O23A_p3149	ENOG4105KW8	RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity)
O23A_p3150	ENOG4107VXZ	Hydrolase
O23A_p3153	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
O23A_p3154	ENOG4105D8J	Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle (By similarity)
O23A_p3155	ENOG4107QQ4	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans (By similarity)
O23A_p3156	ENOG4105CXW	Synthesizes alpha-1,4-glucan chains using ADP-glucose (By similarity)
O23A_p3159	ENOG4105DFD	Na H antiporter
O23A_p3161	ENOG4108UW5	maltose o-acetyltransferase
O23A_p3162	ENOG4105CG3	alpha amylase, catalytic region
O23A_p3163	ENOG4105C5Y	PTS System
O23A_p3164	ENOG4105D4X	repressor
O23A_p3166	ENOG4105CK1	PTS System
O23A_p3167	ENOG4105VZJ	PTS System
O23A_p3168	ENOG4105CK1	PTS System
O23A_p3169	ENOG4105CS2	ec 3.2.1.21
O23A_p3170	ENOG4105VCP	PTS System
O23A_p3171	ENOG4105DKQ	ROK family
O23A_p3174	ENOG4105DDV	Transcriptional regulator (LacI family
O23A_p3176	ENOG4105HDK	L-asparaginase
O23A_p3179	ENOG4108Z5K	methylglyoxal synthase
O23A_p3182	ENOG4108UQY	Iron-storage protein
O23A_p3184	ENOG4105E0I	Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of tRNA(Met), by using acetyl-CoA as an acetyl donor and ATP (or GTP) (By similarity)
O23A_p3185	ENOG410904N	short-chain dehydrogenase reductase
O23A_p3186	ENOG4107R88	Chemotaxis protein (CheV)
O23A_p3188	ENOG4105DWD	nucleoside recognition domain protein
O23A_p3192	ENOG4105K7Z	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP (By similarity)
O23A_p3193	ENOG4107ZVW	dihydroneopterin aldolase
O23A_p3194	ENOG4105K8U	2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
O23A_p3196	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
O23A_p3197	ENOG4105CKI	cobalamin synthesis protein
O23A_p3199	ENOG4105E82	cytochrome subunit of dehydrogenase
O23A_p3202	ENOG4105HEI	LysR family (Transcriptional regulator
O23A_p3203	ENOG4105F6U	Short-chain dehydrogenase reductase Sdr
O23A_p3204	ENOG4105BZU	Histidine kinase
O23A_p3205	ENOG4107QIJ	Aconitate hydratase 2
O23A_p3207	ENOG4108N3W	hemolysin secretion protein
O23A_p3208	ENOG4108N3W	hemolysin secretion protein
O23A_p3210	ENOG4105BZU	Histidine kinase
O23A_p3211	ENOG4107QN2	dihydrolipoyl dehydrogenase
O23A_p3212	ENOG4107QSN	dihydrolipoamide acetyltransferase
O23A_p3213	ENOG4105DAQ	Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) (By similarity)
O23A_p3214	ENOG41073TP	transcriptional regulator
O23A_p3218	ENOG4105D18	nicotinate-nucleotide pyrophosphorylase
O23A_p3220	ENOG4107QHF	type ii secretion system protein e
O23A_p3221	ENOG4105D7Q	type ii secretion system
O23A_p3222	ENOG4105EHH	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue (By similarity)
O23A_p3224	ENOG4105DHA	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity (By similarity)
O23A_p3225	ENOG41067SF	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase (By similarity)
O23A_p3226	ENOG4105M6F	mutator MutT protein
O23A_p3228	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
O23A_p3230	ENOG4105C7C	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
O23A_p3231	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
O23A_p3232	ENOG4105CIT	This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity)
O23A_p3233	ENOG4105K7E	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly (By similarity)
O23A_p3234	ENOG4105DFU	Cell wall formation (By similarity)
O23A_p3235	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
O23A_p3236	ENOG4105CNI	cell division protein FtsW
O23A_p3237	ENOG4105DMZ	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity)
O23A_p3238	ENOG4105CPY	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity)
O23A_p3239	ENOG4108EQQ	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein (By similarity)
O23A_p3240	ENOG4107EEN	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity)
O23A_p3241	ENOG4105CJN	penicillin-binding protein
O23A_p3242	ENOG41063Y6	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity)
O23A_p3243	ENOG4105CGJ	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity)
O23A_p3244	ENOG4108V6E	Cell division protein mraZ
O23A_p3245	ENOG4105CU0	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity)
O23A_p3246	ENOG4105E1C	Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1A (PBP1a) (By similarity)
O23A_p3247	ENOG41082RQ	UPF0102 protein
O23A_p3248	ENOG4105F55	Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate (By similarity)
O23A_p3249	ENOG4105W4M	Transport-associated protein
O23A_p3250	ENOG4105KB2	stringent starvation protein b
O23A_p3251	ENOG4107MKT	Stringent starvation protein a
O23A_p3252	ENOG4105EIX	cytochrome c1
O23A_p3253	ENOG4105DJ5	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
O23A_p3254	ENOG4108R5F	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
O23A_p3256	ENOG4108UJD	30S ribosomal protein S9
O23A_p3257	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
O23A_p3258	ENOG4105D6Z	AFG1 family ATPase
O23A_p3260	ENOG4105C0H	protease
O23A_p3261	ENOG4105C0H	protease
O23A_p3267	ENOG41069H0	dihydroorotase EC 3.5.2.3
O23A_p3270	ENOG4105CTS	PTS system mannitol-specific
O23A_p3271	ENOG41080Z8	PHOSPHOCARRIER protein
O23A_p3272	ENOG4105C21	Displays ATPase and GTPase activities (By similarity)
O23A_p3273	ENOG4107RM2	PTS IIA-like nitrogen-regulatory protein PtsN
O23A_p3274	ENOG41080QH	sigma 54 modulation protein ribosomal protein S30EA
O23A_p3275	ENOG4105DTW	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
O23A_p3276	ENOG4108IUZ	ABC transporter
O23A_p3277	ENOG4105WI0	lipopolysaccharide transport periplasmic protein lptA
O23A_p3278	ENOG4108P1K	Required for the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane (By similarity)
O23A_p3279	ENOG4108Z4R	3-deoxy-d-manno-octulosonate 8-phosphate phosphatase
O23A_p3280	ENOG4105C2X	Arabinose 5-phosphate isomerase
O23A_p3281	ENOG4105DHJ	ABC, transporter
O23A_p3282	ENOG4105CY3	ABC transporter, permease
O23A_p3283	ENOG4107PE3	Mammalian cell entry related domain protein
O23A_p3284	ENOG4105E3I	toluene tolerance
O23A_p3286	ENOG4105VFK	BolA family
O23A_p3287	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
O23A_p3288	ENOG4105CMS	peptidase U62, modulator of DNA gyrase
O23A_p3289	ENOG4105N42	UPF0307 protein
O23A_p3291	ENOG41090HJ	UPF0265 protein
O23A_p3294	ENOG4108JCI	Transcriptional regulator
O23A_p3295	ENOG4105DKK	Benzoate
O23A_p3297	ENOG4105SYT	Methylenetetrahydrofolate reductase
O23A_p3301	ENOG4105EIF	outer membrane protein W
O23A_p3303	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
O23A_p3304	ENOG41086KC	Transcriptional regulator
O23A_p3306	ENOG4108UUM	single-stranded DNA-binding protein
O23A_p3309	ENOG41076HS	cation diffusion facilitator family transporter
O23A_p3311	ENOG4105VEQ	Cold shock protein
O23A_p3312	ENOG4105D05	Receptor
O23A_p3313	ENOG4105BZU	Histidine kinase
O23A_p3314	ENOG4105E0F	Histidine kinase
O23A_p3315	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
O23A_p3320	ENOG4108NVR	Methyl-accepting chemotaxis
O23A_p3322	ENOG4105BZU	Histidine kinase
O23A_p3323	ENOG4108YZA	Nitrogen regulatory protein pii
O23A_p3328	ENOG4105KHA	Glyoxalase Bleomycin resistance protein (Dioxygenase
O23A_p3333	ENOG4107QYX	exodeoxyribonuclease v alpha
O23A_p3334	ENOG4107QKA	exodeoxyribonuclease V beta
O23A_p3335	ENOG4105DSY	exodeoxyribonuclease V, gamma
O23A_p3336	ENOG4108VBZ	doxx family
O23A_p3337	ENOG4105C2I	pirin domain protein
O23A_p3339	ENOG4105CWB	LysR family transcriptional Regulator
O23A_p3347	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
O23A_p3349	ENOG4105BZU	Histidine kinase
O23A_p3353	ENOG4105WCN	acetyltransferase
O23A_p3354	ENOG4105CH6	catalase
O23A_p3360	ENOG4105IPI	Membrane
O23A_p3361	ENOG4108JU9	GAF modulated sigma54 specific transcriptional regulator Fis family
O23A_p3363	ENOG4105VDH	Dihydroxyacetone kinase
O23A_p3364	ENOG4108UTZ	Dihydroxyacetone kinase
O23A_p3365	ENOG4105CMT	Dihydroxyacetone kinase
O23A_p3366	ENOG4105C7N	Xanthine uracil vitamin C permease
O23A_p3369	ENOG4108ZT0	50S ribosomal protein l17
O23A_p3370	ENOG4105CTF	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
O23A_p3371	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
O23A_p3372	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
O23A_p3373	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
O23A_p3374	ENOG4105CGG	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity)
O23A_p3375	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
O23A_p3376	ENOG4105VPB	50S ribosomal protein L30
O23A_p3377	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
O23A_p3378	ENOG4105K4C	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity)
O23A_p3379	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
O23A_p3380	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
O23A_p3381	ENOG4105VBI	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
O23A_p3382	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
O23A_p3383	ENOG4105KAR	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity)
O23A_p3384	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
O23A_p3385	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
O23A_p3386	ENOG41083MP	50s ribosomal protein l29
O23A_p3387	ENOG4108R70	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity)
O23A_p3388	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
O23A_p3389	ENOG4105KAP	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity)
O23A_p3390	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
O23A_p3391	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
O23A_p3392	ENOG41080KG	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
O23A_p3393	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
O23A_p3394	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
O23A_p3395	ENOG4108Z10	Involved in the binding of tRNA to the ribosomes (By similarity)
O23A_p3397	ENOG4105E0F	Histidine kinase
O23A_p3398	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
O23A_p3399	ENOG4108RRZ	Transcription elongation factor GreB
O23A_p3400	ENOG4105BZM	domain protein
O23A_p3404	ENOG4105D3C	The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters (By similarity)
O23A_p3405	ENOG4105MJ2	Competence protein
O23A_p3406	ENOG4107RUK	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins (By similarity)
O23A_p3407	ENOG4105CSF	NADPH-dependent glycerol-3-phosphate dehydrogenase
O23A_p3408	ENOG4105IX2	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA (By similarity)
O23A_p3409	ENOG4107YZP	Rhodanese domain protein
O23A_p3410	ENOG4105CJI	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
O23A_p3411	ENOG41063SB	peptidase
O23A_p3413	ENOG4105DIQ	Transcriptional regulator
O23A_p3414	ENOG4108UHU	Aldolase
O23A_p3415	ENOG4105C01	Dihydroxy-acid dehydratase
O23A_p3416	ENOG4108Z67	carbohydrate kinase, thermoresistant glucokinase family
O23A_p3417	ENOG4105C6Z	Gluconate
O23A_p3418	ENOG4105JIM	Phosphatidylserine synthase
O23A_p3420	ENOG4105CB5	ATP-dependent DNA helicase recG
O23A_p3422	ENOG4105SUU	thioesterase domain
O23A_p3426	ENOG4107R6G	Catalyzes the S-adenosylmethionine monomethyl esterification of trans-aconitate (By similarity)
O23A_p3427	ENOG4108YYA	Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine (By similarity)
O23A_p3428	ENOG4107S2Z	UPF0761 membrane protein
O23A_p3430	ENOG4105C5F	glutamine synthetase
O23A_p3432	ENOG4105CUX	Signal transduction histidine kinase
O23A_p3433	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
O23A_p3434	ENOG4105EKD	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism (By similarity)
O23A_p3435	ENOG4105D4P	Coproporphyrinogen iii oxidase
O23A_p3436	ENOG4105XCT	Protein of unknown function (DUF2489)
O23A_p3437	ENOG4105ZR3	A GTPase-activating protein (GAP) that modifies Der EngA GTPase function. May play a role in ribosome biogenesis (By similarity)
O23A_p3439	ENOG4106RE7	Cytochrome
O23A_p3440	ENOG4105WHM	Necessary for normal cell division and for the maintenance of normal septation (By similarity)
O23A_p3441	ENOG4105F2I	Transposase
O23A_p3442	ENOG4105SG3	Protein of unknown function (DUF1488)
O23A_p3443	ENOG4105E2X	shikimate dehydrogenase
O23A_p3444	ENOG4105DBS	Key enzyme in heme biosynthesis. Catalyzes the oxidative decarboxylation of propionic acid side chains of rings A and B of coproporphyrinogen III (By similarity)
O23A_p3445	ENOG4105EK0	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
O23A_p3447	ENOG4108WI1	Dna topoisomerase
O23A_p3448	ENOG4108RPN	Protein smg homolog
O23A_p3449	ENOG4105C79	DNA protecting protein DprA
O23A_p3451	ENOG4108WZM	domain protein
O23A_p3452	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
O23A_p3453	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
O23A_p3454	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
O23A_p3455	ENOG4105C1A	potassium transporter peripheral membrane
O23A_p3456	ENOG4105D37	Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA (By similarity)
O23A_p3457	ENOG4105CGY	Dna recombination protein
O23A_p3461	ENOG4108TFM	Kinase, PfkB family
O23A_p3462	ENOG4105DCF	alanine dehydrogenase
O23A_p3463	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
O23A_p3464	ENOG4105C26	Dehydrogenase
O23A_p3467	ENOG4105C26	Dehydrogenase
O23A_p3469	ENOG4105FR1	rard protein
O23A_p3470	ENOG4105ECQ	AraC Family Transcriptional Regulator
O23A_p3472	ENOG4105C52	Atpase, p-type (Transporting), had superfamily, subfamily ic
O23A_p3473	ENOG4105CUC	YeeE YedE family protein
O23A_p3476	ENOG410829K	Lysine exporter protein (Lyse ygga)
O23A_p3481	ENOG4105K3G	Periplasmic Protein
O23A_p3488	ENOG41061EV	selenium-binding protein YdfZ
O23A_p3489	ENOG4108UK5	Transposase
O23A_p3491	ENOG4105C4R	Atp-dependent dna helicase
O23A_p3492	ENOG4105DIH	basic membrane
O23A_p3493	ENOG4108JQ9	ABC transporter
O23A_p3494	ENOG4105UIB	(ABC) transporter
O23A_p3496	ENOG4105CC0	LysR family Transcriptional regulator
O23A_p3498	ENOG4105C4W	S-formylglutathione hydrolase
O23A_p3500	ENOG4105E46	N-alpha,N-alpha,N-alpha-trimethyl-L-histidine metabolic process
O23A_p3501	ENOG4105DHU	Bile acid
O23A_p3502	ENOG4105CQ4	Transcriptional regulator
O23A_p3503	ENOG4108Z0R	Transferase
O23A_p3504	ENOG4105C2M	dna polymerase I
O23A_p3506	ENOG4108556	Isoprenoid biosynthesis protein with amidotransferase-like domain
O23A_p3507	ENOG41065UX	Non-essential, abundant cell division factor that is required for proper Z-ring formation. It is recruited early to the divisome by direct interaction with FtsZ, stimulating Z-ring assembly and thereby promoting cell division earlier in the cell cycle. Its recruitment to the Z-ring requires functional FtsA or ZipA (By similarity)
O23A_p3509	ENOG4105D7W	serine acetyltransferase
O23A_p3511	ENOG4105E3W	Two component transcriptional regulator (Winged helix family
O23A_p3512	ENOG4105E0F	Histidine kinase
O23A_p3513	ENOG4108UIQ	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity)
O23A_p3514	ENOG4107R73	Mate efflux family protein
O23A_p3517	ENOG4105DS7	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity)
O23A_p3518	ENOG4105E55	glycerol-3-phosphate acyltransferase
O23A_p3519	ENOG4105C4G	Synthesis of 3-octaprenyl-4-hydroxybenzoate (By similarity)
O23A_p3520	ENOG4105VEI	Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4- hydroxybenzoate (4HB) for the ubiquinone pathway (By similarity)
O23A_p3521	ENOG4105X6C	Flagellar basal body-associated protein FliL
O23A_p3525	ENOG4105D3Z	quinone oxidoreductase, yhdh yhfp family
O23A_p3526	ENOG4105DIQ	Transcriptional regulator
O23A_p3527	ENOG4108XBJ	The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane (By similarity)
O23A_p3530	ENOG4105D8A	3-Deoxy-D-manno-octulosonic-acid transferase
O23A_p3531	ENOG4105XA0	heptosyltransferase ii
O23A_p3533	ENOG4106WTF	Glycosyl transferase, family 2
O23A_p3534	ENOG4105M5K	heptosyltransferase
O23A_p3535	ENOG4108ZEF	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity)
O23A_p3536	ENOG4108MJ5	VirK protein
O23A_p3537	ENOG4105ERD	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity)
O23A_p3539	ENOG4105W0E	50S ribosomal protein L33
O23A_p3540	ENOG4105KDC	50s ribosomal protein l28
O23A_p3541	ENOG4105W5Q	DNA repair protein (RadC
O23A_p3542	ENOG4105CJS	Phosphopantothenoylcysteine decarboxylase
O23A_p3543	ENOG4108Z1K	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA (By similarity)
O23A_p3544	ENOG4105EC0	Required for nucleoid occlusion (NO) phenomenon, which prevents Z-ring formation and cell division over the nucleoid. Acts as a DNA-associated cell division inhibitor that binds simultaneously chromosomal DNA and FtsZ, and disrupts the assembly of FtsZ polymers. SlmA-DNA-binding sequences (SBS) are dispersed on non-Ter regions of the chromosome, preventing FtsZ polymerization at these regions (By similarity)
O23A_p3545	ENOG4105D64	Mechanosensitive ion channel
O23A_p3547	ENOG4107QP8	phosphohexose isomerase
O23A_p3548	ENOG4105C6M	Alpha-keto-beta-hydroxylacyl reductoisomerase
O23A_p3549	ENOG4105EMY	transcriptional regulator
O23A_p3552	ENOG4105CD5	CoA-binding domain protein
O23A_p3555	ENOG4105F03	Provides the (R)-glutamate required for cell wall biosynthesis (By similarity)
O23A_p3556	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
O23A_p3557	ENOG41063Z6	transcriptional regulator, lysR family
O23A_p3560	ENOG4108UM6	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity)
O23A_p3561	ENOG4105CY8	phosphoribosylaminoimidazole carboxylase atpase subunit
O23A_p3562	ENOG4105FCD	Major Facilitator
O23A_p3563	ENOG4105DY9	regulatoR
O23A_p3564	ENOG4108HRK	Histidine kinase
O23A_p3565	ENOG4105BZU	Histidine kinase
O23A_p3566	ENOG4107ZHV	Transcriptional regulator
O23A_p3567	ENOG4108WQH	regulatoR
O23A_p3568	ENOG4105BZU	Histidine kinase
O23A_p3573	ENOG4105UGQ	Fimbrial
O23A_p3576	ENOG4108FZ9	Chaperone
O23A_p3577	ENOG4106PG1	outer membrane usher protein
O23A_p3583	ENOG4105CBX	hi0933 family
O23A_p3584	ENOG41090A1	ferritin
O23A_p3585	ENOG4105BZU	Histidine kinase
O23A_p3586	ENOG4105RKW	reductase (By
O23A_p3587	ENOG4108M6U	Universal stress protein A
O23A_p3593	ENOG4105EMK	carboxylate amino acid amine transporter
O23A_p3595	ENOG4108W7E	Catalyzes the ATP-dependent phosphorylation of the 3- deoxy-D-manno-octulosonic acid (Kdo) residue in Kdo-lipid IV(A) at the 4-OH position (By similarity)
O23A_p3596	ENOG4105DKP	glycosyl transferase, family 9
O23A_p3598	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
O23A_p3599	ENOG4105VFG	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity)
O23A_p3600	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
O23A_p3601	ENOG4105FE8	tRNA (Guanosine-2'-O-)-methyltransferase
O23A_p3602	ENOG4108EUD	Lysophospholipase
O23A_p3603	ENOG4105DQF	Hydrolase
O23A_p3606	ENOG4105Y7M	Transcriptional regulator, TetR family
O23A_p3607	ENOG410624X	efflux transporter, rnd family, mfp subunit
O23A_p3608	ENOG4105BZS	acriflavin resistance protein
O23A_p3609	ENOG4105BZU	Histidine kinase
O23A_p3610	ENOG4105DC8	reductase
O23A_p3612	ENOG4105D9K	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity)
O23A_p3613	ENOG4105C8X	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity)
O23A_p3616	ENOG4105C08	Histidine kinase
O23A_p3617	ENOG4105EEX	Two component transcriptional regulator (Winged helix family
O23A_p3618	ENOG4105C2C	drug resistance transporter, Bcr CflA
O23A_p3620	ENOG4105JKW	Valine--pyruvate aminotransferase
O23A_p3621	ENOG4108ZNX	Heat shock protein
O23A_p3622	ENOG4108ZNX	Heat shock protein
O23A_p3623	ENOG4105IGJ	Zn-dependent Hydrolase of the beta-lactamase fold protein
O23A_p3624	ENOG4105ECQ	AraC Family Transcriptional Regulator
O23A_p3625	ENOG4105D29	Helix-turn-helix type 11 domain protein
O23A_p3628	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
O23A_p3629	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
O23A_p3630	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
O23A_p3631	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
O23A_p3633	ENOG4105EAB	amino acid AbC transporter
O23A_p3634	ENOG4105E5Q	amino acid AbC transporter
O23A_p3635	ENOG4105CDA	abc transporter atp-binding protein
O23A_p3636	ENOG4105VG0	50S ribosomal protein l34
O23A_p3637	ENOG4105NVJ	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme (By similarity)
O23A_p3638	ENOG4105DHW	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
O23A_p3639	ENOG4105C1H	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity)
O23A_p3642	ENOG4105C0W	non-ribosomal peptide synthetase
O23A_p3644	ENOG4105CEY	Amp-dependent synthetase and ligase
O23A_p3650	ENOG4108IPW	abc transporter atp-binding protein
O23A_p3653	ENOG4105S6R	Iron-hydroxamate transporter permease subunit
O23A_p3654	ENOG4105J76	Periplasmic binding protein
O23A_p3656	ENOG4105E0A	ABC, transporter
O23A_p3657	ENOG4105IBP	Cyclic peptide transporter
O23A_p3658	ENOG4105E0K	tonB-dependent siderophore receptor
O23A_p3659	ENOG4105QTB	Flavodoxin
O23A_p3660	ENOG4107RE5	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity)
O23A_p3661	ENOG4105D28	Specifically methylates the N7 position of a guanine in 16S rRNA (By similarity)
O23A_p3662	ENOG4107QJE	Chromosome Partitioning Protein
O23A_p3663	ENOG4105FA0	parb-like partition protein
O23A_p3664	ENOG410684E	atp synthase
O23A_p3665	ENOG4105EE4	it plays a direct role in the translocation of protons across the membrane (By similarity)
O23A_p3666	ENOG4105KY6	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
O23A_p3667	ENOG4107Z6K	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
O23A_p3668	ENOG4107S15	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
O23A_p3669	ENOG4105CDG	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity)
O23A_p3670	ENOG4105J80	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity)
O23A_p3671	ENOG4105C4J	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity)
O23A_p3672	ENOG4105KNM	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
O23A_p3673	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
O23A_p3674	ENOG4105CT7	inner membrane cred family protein
O23A_p3676	ENOG4105EB3	Histidine kinase
O23A_p3677	ENOG4105E3W	Two component transcriptional regulator (Winged helix family
O23A_p3678	ENOG410804X	Transcriptional regulator
O23A_p3679	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
O23A_p3680	ENOG4105VJY	transcriptional regulator
O23A_p3684	ENOG4109015	Biopolymer transport protein exbD tolR
O23A_p3685	ENOG410822N	TonB family
O23A_p3688	ENOG4105DZC	cytosine deaminase
O23A_p3689	ENOG4105WMR	Protein CrcB homolog
O23A_p3690	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
O23A_p3691	ENOG4105JC1	sterol-binding domain protein
O23A_p3692	ENOG4105CNK	Required, probably indirectly, for the hydroxylation of 2-octaprenylphenol to 2-octaprenyl-6-hydroxy-phenol, the fourth step in ubiquinone biosynthesis (By similarity)
O23A_p3693	ENOG4105WKS	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity)
O23A_p3694	ENOG4105X8U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation (By similarity)
O23A_p3695	ENOG4105DCX	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity)
O23A_p3696	ENOG4105F8V	Hydrolase, tatD family
O23A_p3697	ENOG4105D52	delta-aminolevulinic acid dehydratase
O23A_p3698	ENOG4105DGW	oligopeptidase A
O23A_p3699	ENOG4105BZU	Histidine kinase
O23A_p3701	ENOG4105FFN	Specifically methylates the guanosine in position 1516 of 16S rRNA (By similarity)
O23A_p3703	ENOG4105C9X	ppx gppa phosphatase
O23A_p3704	ENOG4105C1J	atp-dependent rna helicase
O23A_p3705	ENOG4105K63	Thioredoxin
O23A_p3706	ENOG4105C4P	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity)
O23A_p3708	ENOG4105D3H	Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol (By similarity)
O23A_p3709	ENOG4107QK7	reductase
O23A_p3710	ENOG4105W0Z	cytoplasmic protein
O23A_p3713	ENOG4105M78	Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide (By similarity)
O23A_p3716	ENOG4108IV0	ABC, transporter
O23A_p3717	ENOG4105C0Z	ABC transporter
O23A_p3718	ENOG4105CF8	branched-chain amino acid ABC transporter, permease
O23A_p3719	ENOG4105C32	Amino acid ABC transporter (Permease)
O23A_p3720	ENOG4105CP9	extracellular ligand-binding receptor
O23A_p3721	ENOG4105ETE	Transcriptional regulator (LacI family
O23A_p3722	ENOG4105F8D	glycoside hydrolase family 4
O23A_p3723	ENOG4105CI1	PTS System
O23A_p3724	ENOG4105FDP	GntR family transcriptional regulator
O23A_p3725	ENOG4108JUA	Transcriptional regulator
O23A_p3726	ENOG4105CNW	domain protein
O23A_p3727	ENOG4108EQM	faD-dependent pyridine nucleotide-disulfide oxidoreductase
O23A_p3730	ENOG4105HEE	Binding Domain protein
O23A_p3731	ENOG4105CIC	tryptophan-specific transport protein
O23A_p3734	ENOG4108ZHR	arsR family transcriptional regulator
O23A_p3737	ENOG4105BZU	Histidine kinase
O23A_p3739	ENOG4108I67	Catalyzes the synthesis of activated sulfate (By similarity)
O23A_p3741	ENOG4105C38	Glycyl-tRNA synthetase beta subunit
O23A_p3742	ENOG4108HMW	glycyl-tRNA synthetase, alpha subunit
O23A_p3743	ENOG4108R3E	Dna-3-methyladenine glycosylase i
O23A_p3744	ENOG4108ZG0	Ompa motb domain protein
O23A_p3745	ENOG4105M4H	endoribonuclease L-psp
O23A_p3746	ENOG41082K8	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Interacts with IscS and stimulates its activity. Then, accepts a sulfur from IscS and transfers it in turn to TusD (By similarity)
O23A_p3750	ENOG4105E0F	Histidine kinase
O23A_p3751	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
O23A_p3752	ENOG4105CHU	acetyl-coa acetyltransferase
O23A_p3753	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
O23A_p3754	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
O23A_p3755	ENOG4105D9Y	Splits dipeptides with a prolyl residue in the C- terminal position (By similarity)
O23A_p3756	ENOG4108ZK7	protein family UPF0029, Impact, N-terminal protein
O23A_p3757	ENOG4105D37	Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA (By similarity)
O23A_p3758	ENOG4108RR8	protoporphyrinogen oxidase
O23A_p3760	ENOG4105CUZ	uba thif-type nad fad binding protein
O23A_p3761	ENOG4105P9C	Participates in cysteine desulfuration mediated by SufS. Cysteine desulfuration mobilizes sulfur from L-cysteine to yield L-alanine and constitutes an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules. Functions as a sulfur acceptor for SufS, by mediating the direct transfer of the sulfur atom from the S-sulfanylcysteine of SufS, an intermediate product of cysteine desulfuration process (By similarity)
O23A_p3762	ENOG4105C9B	Cysteine desulfurase
O23A_p3764	ENOG4105C4R	Atp-dependent dna helicase
O23A_p3765	ENOG4105BZU	Histidine kinase
O23A_p3767	ENOG4105CPQ	Dehydrogenase
O23A_p3768	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
O23A_p3769	ENOG41062JF	Transcriptional regulator
O23A_p3770	ENOG4105CUI	Catalyzes the interconversion between ADP-D-glycero- beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose (By similarity)
O23A_p3771	ENOG4105CG5	Glycosyl transferase (Group 1
O23A_p3774	ENOG4107J0A	lipopolysaccharide biosynthetic process
O23A_p3775	ENOG4105XA0	heptosyltransferase ii
O23A_p3777	ENOG4105DSJ	YicC domain protein
O23A_p3779	ENOG4107QP2	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
O23A_p3781	ENOG4108Z6Z	Transcriptional regulator
O23A_p3783	ENOG4105PC1	Conserved Protein
O23A_p3785	ENOG4105E27	serine threonine protein kinase
O23A_p3786	ENOG4108Z33	Thiol disulfide Interchange Protein
O23A_p3787	ENOG4105S7S	phosphonate abc transporter
O23A_p3788	ENOG4108VA1	ABC transporter
O23A_p3789	ENOG4105EHI	Phosphonate ABC transporter, periplasmic
O23A_p3790	ENOG4107RH7	Nicotinate phosphoribosyltransferase
O23A_p3792	ENOG4108RWI	nicotinamidase
O23A_p3795	ENOG4106HNH	Acyl-transferase
O23A_p3796	ENOG4105C0P	Mg chelatase subunit ChlI
O23A_p3809	ENOG41088T4	Helicase IV
O23A_p3811	ENOG4105C0P	Mg chelatase subunit ChlI
O23A_p3813	ENOG4105P3Y	Acetolactate synthase 2 regulatory subunit
O23A_p3814	ENOG4105CM2	brancheD-chain amino acid aminotransferase
O23A_p3815	ENOG4105C01	Dihydroxy-acid dehydratase
O23A_p3816	ENOG4105C7B	Threonine dehydratase
O23A_p3817	ENOG4105UYK	outer membrane protein a
O23A_p3819	ENOG4105XEA	Tetr family transcriptional regulator
O23A_p3821	ENOG4105C25	Primosomal protein n'
O23A_p3822	ENOG4105VFB	Binds the 23S rRNA (By similarity)
O23A_p3823	ENOG4105CGD	Nad-dependent epimerase dehydratase
O23A_p3824	ENOG4105C6K	Malic enzyme
O23A_p3826	ENOG4105JJR	Histidine kinase
O23A_p3829	ENOG4107R9T	Catalyzes the formation of 5-methyl-uridine at position 54 (m5U54) in all tRNAs (By similarity)
O23A_p3835	ENOG4105EQQ	protein containing aminopeptidase domain
O23A_p3839	ENOG4105D2T	synthase
O23A_p3841	ENOG4105F0R	Cytidylyltransferase
O23A_p3844	ENOG4105CHR	reductase
O23A_p3845	ENOG4105CEY	Amp-dependent synthetase and ligase
O23A_p3849	ENOG4105CND	Glycosyl transferase, family 2
O23A_p3852	ENOG4105K64	Glycosyl transferase, family 2
O23A_p3858	ENOG4107UCJ	Catalyzes the synthesis of activated sulfate (By similarity)
O23A_p3861	ENOG4105P12	pyruvate phosphate dikinase
O23A_p3862	ENOG4108Z86	Glutamine amidotransferase
O23A_p3863	ENOG4107Z36	nucleotidyl transferase
O23A_p3864	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
O23A_p3865	ENOG4105C5E	polysaccharide biosynthesis protein
O23A_p3866	ENOG4107R28	alpha amylase, catalytic region
O23A_p3869	ENOG4105R8A	Heat shock protein
O23A_p3870	ENOG4105C5I	Dehydrogenase
O23A_p3871	ENOG4108RH0	Crea protein
O23A_p3873	ENOG4108V7X	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
O23A_p3874	ENOG4105CFQ	glutamine synthetase
O23A_p3875	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
O23A_p3877	ENOG4108HM4	ABC transporter
O23A_p3878	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
O23A_p3879	ENOG4105F38	ABC transporter, permease
O23A_p3880	ENOG4105D38	putrescine abc transporter
O23A_p3881	ENOG4108RPX	mosc domain containing protein
O23A_p3884	ENOG4108VUY	thioesterase Superfamily protein
O23A_p3885	ENOG4105C9U	ATP-dependent DNA helicase RecQ
O23A_p3886	ENOG4105N7H	Cytochrome
O23A_p3887	ENOG4105CNG	UPF0061 protein
O23A_p3889	ENOG4105EX9	Membrane
O23A_p3891	ENOG4108YYX	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. Modulates RNA-binding and helicase activities of the degradosome (By similarity)
O23A_p3892	ENOG4108NVR	Methyl-accepting chemotaxis
O23A_p3893	ENOG4105CJW	magnesium transporter
O23A_p3894	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
O23A_p3895	ENOG4107V9H	nitrite transporter
O23A_p3896	ENOG4105WZK	nitrite reductase NADPH small subunit
O23A_p3898	ENOG4107QZF	nitrite reductase NADPH large subunit
O23A_p3900	ENOG4105C57	major facilitator superfamily
O23A_p3901	ENOG4105C4N	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis (By similarity)
O23A_p3902	ENOG4108R5P	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery (By similarity)
O23A_p3904	ENOG4105C75	arginyL-tRNA synthetase
O23A_p3906	ENOG4105K6V	RNA polymerase
O23A_p3908	ENOG4105DWR	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity)
O23A_p3909	ENOG4105CPC	Aldo Keto reductase
O23A_p3910	ENOG4105ENN	converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose (By similarity)
O23A_p3912	ENOG4105CRD	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P) (By similarity)
O23A_p3913	ENOG4105F0Z	galactose-1-phosphate uridylyltransferase
O23A_p3914	ENOG4105CMR	udp-glucose 4-epimerase
O23A_p3915	ENOG41060NJ	transcriptional regulator
O23A_p3916	ENOG4105CNT	hydrolase family 2
O23A_p3920	ENOG4108HWV	)-transporter
O23A_p3921	ENOG4105C8Q	Methyl-accepting chemotaxis
O23A_p3928	ENOG4105C5B	carbamate kinase
O23A_p3929	ENOG4105DBV	ornithine carbamoyltransferase
O23A_p3930	ENOG4105CSX	c4-dicarboxylate anaerobic carrier
O23A_p3931	ENOG410682Y	Regulates arginine biosynthesis genes (By similarity)
O23A_p3932	ENOG4108R9M	Involved in allosteric regulation of aspartate carbamoyltransferase (By similarity)
O23A_p3933	ENOG4105CXT	aspartate transcarbamylase
O23A_p3936	ENOG4105DJ4	phosphatidylserine decarboxylase
O23A_p3938	ENOG4105C8Q	Methyl-accepting chemotaxis
O23A_p3939	ENOG4105QNF	Outer membrane lipoprotein
O23A_p3940	ENOG4105CF7	AraC family transcriptional regulator
O23A_p3941	ENOG4108I6A	alcohol dehydrogenase
O23A_p3942	ENOG4108IIE	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
O23A_p3943	ENOG4105C15	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
O23A_p3945	ENOG4105WWK	YheO domain protein
O23A_p3946	ENOG4105CEM	UPF0597 protein
O23A_p3948	ENOG4107QMW	pyridine nucleotide-disulfide oxidoreductase
O23A_p3949	ENOG4106SNF	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
O23A_p3950	ENOG4105C34	Pseudouridine synthase
O23A_p3951	ENOG4105DBW	Multi-copper polyphenol oxidoreductase laccase
O23A_p3952	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
O23A_p3953	ENOG4107T8T	UPF0173 metal-dependent hydrolase
O23A_p3954	ENOG4105CU9	asparagine synthetase A
O23A_p3955	ENOG4108VVK	transcriptional Regulator, AsnC
O23A_p3958	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
O23A_p3959	ENOG410642E	Short chain dehydrogenase
O23A_p3962	ENOG4107WP9	Histidine kinase
O23A_p3964	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
O23A_p3965	ENOG4108UQ5	membrane protein YcdZ
O23A_p3967	ENOG4105CCD	The exact function is not known. Can catalyze the reduction of a variety of substrates like dimethyl sulfoxide, trimethylamine N-oxide, phenylmethyl sulfoxide and L-methionine sulfoxide. Cannot reduce cyclic N-oxides. Shows no activity as sulfite oxidase (By similarity)
O23A_p3968	ENOG4105DQ2	Is probably involved in the electron transfer between its heme and the molybdenum cofactor of the reductase catalytic subunit YedY (By similarity)
O23A_p3971	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
O23A_p3972	ENOG4105IFJ	Histidine kinase
O23A_p3974	ENOG4107QY8	reductase
O23A_p3975	ENOG4105CUW	cytochrome C-TYPE protein
O23A_p3976	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
O23A_p3978	ENOG4107ZYR	domain protein
O23A_p3979	ENOG4105D4A	Cell wall formation (By similarity)
O23A_p3980	ENOG4105HJX	Biotin- acetyl-CoA-carboxylase ligase
O23A_p3982	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
O23A_p3983	ENOG4105PM1	preprotein translocase subunit SecE
O23A_p3984	ENOG4105E5V	Participates in transcription elongation, termination and antitermination (By similarity)
O23A_p3985	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
O23A_p3986	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
O23A_p3987	ENOG4108VZM	50s ribosomal protein L10
O23A_p3988	ENOG4105KBC	Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity)
O23A_p3989	ENOG4108IIJ	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
O23A_p3990	ENOG4105D27	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
O23A_p3991	ENOG4105WWK	YheO domain protein
O23A_p3992	ENOG4105KME	endoribonuclease L-psp
O23A_p3994	ENOG4108ZKU	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions (By similarity)
O23A_p3995	ENOG4105YKK	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions (By similarity)
O23A_p3996	ENOG4108UKE	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity)
O23A_p3997	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
O23A_p3998	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
O23A_p3999	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
O23A_p4000	ENOG4108ZI0	d,d-heptose 1,7-bisphosphate phosphatase
O23A_p4004	ENOG4105CKD	glutathione-regulated potassium-efflux system protein
O23A_p4005	ENOG4108K2R	Glutathione-regulated potassium-efflux system ancillary protein
O23A_p4008	ENOG4105CUG	Oligopeptidase b
O23A_p4012	ENOG4107FS9	Membrane
O23A_p4015	ENOG4105JQN	Transcriptional regulator
O23A_p4018	ENOG4105VVZ	metal-binding protein
O23A_p4019	ENOG41076UM	multiple antibiotic resistance (MarC)-related protein
O23A_p4021	ENOG4105WKS	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity)
O23A_p4024	ENOG4105CHQ	Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella (By similarity)
O23A_p4026	ENOG4107RZC	phospholipase d
O23A_p4028	ENOG4105EJ2	Transcriptional regulator
O23A_p4032	ENOG4106H78	methyltransferase
O23A_p4033	ENOG4105CCP	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
O23A_p4034	ENOG4105CAK	Cell division ATP-binding protein ftsE
O23A_p4035	ENOG4105CRP	Part of the ABC transporter FtsEX involved in
O23A_p4036	ENOG4105DEK	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
O23A_p4038	ENOG41077A9	carbonic anhydrase
O23A_p4039	ENOG4105CZE	histidine utilization repressor
O23A_p4040	ENOG4105CI2	imidazolone-5-propionate hydrolase
O23A_p4041	ENOG41088SP	formiminoglutamate hydrolase
O23A_p4042	ENOG4105CGP	Urocanate hydratase
O23A_p4043	ENOG4105C84	Histidine ammonia-lyase
O23A_p4044	ENOG4105EWV	Sodium calcium exchanger membrane region
O23A_p4047	ENOG41062P1	Diguanylate cyclase phosphodiesterase
O23A_p4053	ENOG4105GVR	general secretion pathway protein D
O23A_p4056	ENOG4107QHF	type ii secretion system protein e
O23A_p4057	ENOG4105D7Q	type ii secretion system
O23A_p4061	ENOG4106855	Competence protein
O23A_p4066	ENOG4105DFF	Rod shape-determining protein mreb
O23A_p4067	ENOG4105N3I	Involved in formation and maintenance of cell shape (By similarity)
O23A_p4068	ENOG4105VQ7	Rod shape-determining protein MreD
O23A_p4069	ENOG4108Z03	MAF-like protein
O23A_p4070	ENOG4105C03	ribonuclease
O23A_p4071	ENOG4105QD6	exported protein
O23A_p4074	ENOG4105D1U	peptidase U62 modulator of DNA gyrase
O23A_p4077	ENOG4105CSH	Transporter
O23A_p4079	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
O23A_p4080	ENOG4105BZU	Histidine kinase
O23A_p4081	ENOG4105QD0	anti-sigma regulatory factor serine threonine protein kinase
O23A_p4082	ENOG4107MMM	Anti-sigma-factor antagonist
O23A_p4083	ENOG4107SDU	Methyl-accepting chemotaxis
O23A_p4084	ENOG4105F0S	class B acid phosphatase
O23A_p4087	ENOG4108HU6	Metal dependent phosphohydrolase
O23A_p4090	ENOG4105EEQ	Na H antiporter
O23A_p4091	ENOG4105C3R	Methionine synthase
O23A_p4092	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
O23A_p4094	ENOG4105ETX	regulatoR
O23A_p4098	ENOG4105CBF	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction (By similarity)
O23A_p4099	ENOG4108UV6	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity)
O23A_p4100	ENOG4105D06	uba thif-type nad fad binding protein
O23A_p4102	ENOG4105CA8	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity)
O23A_p4103	ENOG4105D41	biosynthesis protein thiH
O23A_p4105	ENOG4108UK2	deaminase
O23A_p4107	ENOG4108Z9I	-acetyltransferase
O23A_p4108	ENOG4105EQK	-acetyltransferase
O23A_p4109	ENOG4108WEF	Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1B (PBP1b) (By similarity)
O23A_p4113	ENOG4105C44	Serine transporter
O23A_p4114	ENOG4108TPP	exopolysaccharide synthesis
O23A_p4116	ENOG4105N0V	mono-oxygenase ydhR
O23A_p4117	ENOG4105KVH	Transcriptional regulator
O23A_p4122	ENOG4105E0K	tonB-dependent siderophore receptor
O23A_p4125	ENOG4105CBT	Fructose-1,6-bisphosphatase
O23A_p4128	ENOG4105ECF	c-methyltransferase
O23A_p4129	ENOG41076E6	Uroporphyrinogen-III Synthase
O23A_p4130	ENOG4105D6W	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity)
O23A_p4131	ENOG4107T0K	Adenylate cyclase
O23A_p4132	ENOG4106CJB	Phospholipase Carboxylesterase
O23A_p4133	ENOG4105XQ6	frataxin-like protein
O23A_p4135	ENOG4105CU5	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity)
O23A_p4136	ENOG4105E4Z	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan (By similarity)
O23A_p4138	ENOG4108IYS	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
O23A_p4139	ENOG4105DFC	had-superfamily hydrolase, subfamily ia, variant
O23A_p4141	ENOG4105D64	Mechanosensitive ion channel
O23A_p4143	ENOG4108Z86	Glutamine amidotransferase
O23A_p4144	ENOG410667J	hydrolase
O23A_p4147	ENOG4105CJ1	ABC, transporter
O23A_p4149	ENOG4108I62	cina-like protein
O23A_p4150	ENOG4105E4Y	Endoribonuclease that initiates mRNA decay (By similarity)
O23A_p4151	ENOG4105CVG	Homoserine O-transsuccinylase
O23A_p4153	ENOG4108YXU	transcriptional regulator AsnC family
O23A_p4154	ENOG4105E0M	Sulfatase
O23A_p4159	ENOG4105KT7	mgtC SapB transporter
O23A_p4163	ENOG4105EMU	Dehydrogenase
O23A_p4164	ENOG4105DZW	Dipeptidase
O23A_p4167	ENOG4108I6A	alcohol dehydrogenase
O23A_p4169	ENOG4108IQK	o-acetylhomoserine
O23A_p4172	ENOG4105C1X	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity (By similarity)
O23A_p4176	ENOG4107IFA	Lipase (EC 3.1.1.3)
O23A_p4178	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
O23A_p4179	ENOG4108UB4	uncharacterized protein ygjQ
O23A_p4180	ENOG4107MM9	BNR Asp-box repeat-containing protein
O23A_p4183	ENOG4105HMV	Fimbrial protein
O23A_p4185	ENOG4106PG1	outer membrane usher protein
O23A_p4186	ENOG4108FZ9	Chaperone
O23A_p4187	ENOG4105NEV	Fimbrial
O23A_p4190	ENOG4105CEY	Amp-dependent synthetase and ligase
O23A_p4191	ENOG4105DNI	Converts SHCHC to OSB (By similarity)
O23A_p4192	ENOG4108IPT	Naphthoate synthase
O23A_p4193	ENOG4107J5P	Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC). Is also able to catalyze the hydrolysis of the thioester bond in palmitoyl-CoA in vitro (By similarity)
O23A_p4194	ENOG4105C4A	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC) (By similarity)
O23A_p4195	ENOG4105E4F	Isochorismate synthase
O23A_p4196	ENOG4105EIS	1,4-dihydroxy-2-naphthoate octaprenyltransferase
O23A_p4202	ENOG4105C1J	atp-dependent rna helicase
O23A_p4204	ENOG4105D9N	nucleoside
O23A_p4205	ENOG4107K5X	Membrane-bound metal-dependent hydrolase
O23A_p4208	ENOG4108UPT	UPF0178 protein
O23A_p4212	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
O23A_p4213	ENOG4105C3N	Participates in control of cell volume in low-osmolarity conditions (By similarity)
O23A_p4214	ENOG4105E61	Mannitol repressor protein
O23A_p4215	ENOG4107SQ3	mannitol-1-phosphate 5-dehydrogenase
O23A_p4216	ENOG4105CTS	PTS system mannitol-specific
O23A_p4220	ENOG4108IEC	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction (By similarity)
O23A_p4221	ENOG4105CXD	Specific inhibitor of chromosomal initiation of replication in vitro. Binds the three 13-mers in the origin (oriC) to block initiation of replication (By similarity)
O23A_p4223	ENOG4105NNS	Autoinducer synthesis protein
O23A_p4224	ENOG4105VJY	transcriptional regulator
O23A_p4225	ENOG4108ZUB	Lysine exporter protein (Lyse ygga)
O23A_p4226	ENOG4107RNS	bifunctional 2',3'-cyclic nucleotide 2'-phosphodiesterase 3'-nucleotidase periplasmic
O23A_p4227	ENOG4108XTF	Outer Membrane Lipoprotein
O23A_p4228	ENOG4108R6G	acetyltransferase
O23A_p4229	ENOG4105VXR	cytoplasmic protein
O23A_p4232	ENOG4105DJ1	Phosphoenolpyruvate Carboxylase
O23A_p4233	ENOG4105F4C	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress (By similarity)
O23A_p4234	ENOG4105VEJ	Heat shock protein
O23A_p4235	ENOG4108XKW	General secretion pathway protein C
O23A_p4236	ENOG4105GVR	general secretion pathway protein D
O23A_p4237	ENOG4107QHF	type ii secretion system protein e
O23A_p4238	ENOG4105D7Q	type ii secretion system
O23A_p4239	ENOG4108VAU	general secretion pathway protein G
O23A_p4249	ENOG4108UDW	Transcriptional regulator, luxr family
O23A_p4250	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
O23A_p4251	ENOG4107Y3D	HAD-superfamily hydrolase subfamily IA variant 3
O23A_p4252	ENOG4107RK2	ADP-ribose diphosphatase NudE
O23A_p4253	ENOG4108RNI	3'(2')5'-bisphosphate nucleotidase
O23A_p4254	ENOG4105C44	Serine transporter
O23A_p4255	ENOG4108Z7R	Chaperone CsaA
O23A_p4257	ENOG4105GGQ	This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis (By similarity)
O23A_p4258	ENOG4105C28	cystathionine
O23A_p4259	ENOG4105CFH	Aspartokinase
O23A_p4262	ENOG41067MG	lrgb family
O23A_p4264	ENOG4105CMU	LysR family (Transcriptional regulator
O23A_p4270	ENOG4108Z66	YbaK ebsC protein
O23A_p4271	ENOG4107TH8	cina domain protein
O23A_p4272	ENOG4105C68	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity)
O23A_p4274	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
O23A_p4275	ENOG4105CFH	Aspartokinase
O23A_p4276	ENOG4105VM8	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding (By similarity)
O23A_p4278	ENOG41061WM	D-Alanyl-D-Alanine
O23A_p4279	ENOG4106W5V	Membrane
O23A_p4282	ENOG4105MYG	DNA polymerase iii, chi subunit
O23A_p4283	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
O23A_p4285	ENOG4108M8S	permease YjgP YjgQ family protein
O23A_p4286	ENOG4108K5H	permease YjgP YjgQ family protein
O23A_p4288	ENOG4105BZU	Histidine kinase
O23A_p4289	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
O23A_p4290	ENOG4105VDT	-acetyltransferase
O23A_p4292	ENOG4105X0D	Fimbrial protein
O23A_p4293	ENOG4105EYA	deoxyribonuclease
O23A_p4294	ENOG4105D9N	nucleoside
O23A_p4296	ENOG4105FCI	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate (By similarity)
O23A_p4297	ENOG4105CMW	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis (By similarity)
O23A_p4298	ENOG4105CZG	Phosphotransfer between the C1 and C5 carbon atoms of pentose (By similarity)
O23A_p4299	ENOG4105D3A	purine nucleoside phosphorylase DeoD-type
O23A_p4302	ENOG4105EAC	phosphoserine phosphatase
O23A_p4305	ENOG4105DNJ	May play a role in the repair of endogenous alkylation damage (By similarity)
O23A_p4307	ENOG4108ZVW	Anti-RNA polymerase sigma 70 factor
O23A_p4309	ENOG4105K70	DNA-binding protein
O23A_p4312	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
O23A_p4316	ENOG4105CWM	branched-chain amino acid transport system II carrier protein
O23A_p4318	ENOG4107S47	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC) (By similarity)
O23A_p4319	ENOG4105C1J	atp-dependent rna helicase
O23A_p4320	ENOG4105D1Q	UPF0246 protein
O23A_p4321	ENOG4105CZX	twitching motility protein
O23A_p4322	ENOG4105CZX	twitching motility protein
O23A_p4323	ENOG4105DFA	alanine racemase domain protein
O23A_p4324	ENOG4105II7	pyrroline-5-carboxylate reductase
O23A_p4325	ENOG4108VIA	integral membrane protein
O23A_p4326	ENOG4105VZ9	UPF0235 protein
O23A_p4329	ENOG4107QSI	ABC, transporter
O23A_p4331	ENOG4105EQK	-acetyltransferase
O23A_p4332	ENOG4106WH9	Protein of unknown function (DUF2753)
O23A_p4333	ENOG41060WC	Enoyl-CoA hydratase
O23A_p4336	ENOG4108RZ4	Short-chain dehydrogenase reductase Sdr
O23A_p4338	ENOG4105DWY	Agmatine deiminase
O23A_p4339	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
O23A_p4341	ENOG4107YH7	Beta-lactamase (EC 3.5.2.6)
O23A_p4344	ENOG4105C1J	atp-dependent rna helicase
O23A_p4348	ENOG4107V4F	S-adenosyl-l-methionine hydroxide adenosyltransferase
O23A_p4354	ENOG4107QWG	2-Nitropropane dioxygenase
O23A_p4358	ENOG4105E0F	Histidine kinase
O23A_p4359	ENOG4105E3W	Two component transcriptional regulator (Winged helix family
O23A_p4360	ENOG4105DJY	efflux transporter, rnd family, mfp subunit
O23A_p4361	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
O23A_p4365	ENOG4108GAE	asmA family
O23A_p4367	ENOG4105CYX	Short-chain dehydrogenase reductase Sdr
O23A_p4368	ENOG4105CE6	Adenylation and deadenylation of glutamate--ammonia ligase (By similarity)
O23A_p4370	ENOG410787A	Pts system, glucitol sorbitol-specific
O23A_p4371	ENOG4105DZY	Pts system, glucitol sorbitol-specific
O23A_p4372	ENOG4105VI0	Pts system, glucitol sorbitol-specific
O23A_p4374	ENOG4107QMF	Sorbitol-6-phosphate dehydrogenase
O23A_p4376	ENOG410804X	Transcriptional regulator
O23A_p4377	ENOG4105CE6	Adenylation and deadenylation of glutamate--ammonia ligase (By similarity)
O23A_p4381	ENOG4105CJH	Alcohol dehydrogenase zinc-binding domain protein
O23A_p4382	ENOG4108ZHJ	Organic hydroperoxide resistance protein
O23A_p4383	ENOG4105K56	Transcriptional regulator
O23A_p4386	ENOG4105EW9	transcriptional regulator AsnC family
O23A_p4390	ENOG4108K4B	hydrolase
O23A_p4393	ENOG4105C8J	)-transporter
O23A_p4395	ENOG4105C8J	)-transporter
O23A_p4400	ENOG4107SQD	Transcriptional regulator, GntR family
O23A_p4405	ENOG4105XEP	YhcH YjgK YiaL family protein
O23A_p4407	ENOG4105CUY	Mechanosensitive ion channel
O23A_p4408	ENOG4107N1Q	ErfK YbiS YcfS YnhG family protein
O23A_p4409	ENOG4105CK7	Sodium proline symporter
O23A_p4418	ENOG4105D6S	protein involved in catabolism of external DNA
O23A_p4420	ENOG4105C5H	ABC transporter
O23A_p4421	ENOG4105C2X	Arabinose 5-phosphate isomerase
O23A_p4422	ENOG4105G5H	Membrane
O23A_p4423	ENOG4107QX8	SPFH domain, Band 7 family protein
O23A_p4424	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
O23A_p4425	ENOG4105C11	sulfate adenylyltransferase), subunit 2
O23A_p4426	ENOG4105C3T	may be the GTPase, regulating ATP sulfurylase activity (By similarity)
O23A_p4429	ENOG4108I67	Catalyzes the synthesis of activated sulfate (By similarity)
O23A_p4432	ENOG4107RHT	methyl-accepting chemotaxis sensory transducer with Pas Pac sensor
O23A_p4439	ENOG4108UUE	Transcriptional regulator
O23A_p4443	ENOG4105DKQ	ROK family
O23A_p4444	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
O23A_p4445	ENOG4105BZA	Phosphoglycerate kinase
O23A_p4446	ENOG4105D2N	Aldolase
O23A_p4447	ENOG4105CJP	fad dependent oxidoreductase
O23A_p4454	ENOG4105DUM	transcriptional regulator, lysR family
O23A_p4458	ENOG4108IYU	L-aspartate oxidase
O23A_p4459	ENOG4105EMN	RNA polymerase sigma factor
O23A_p4460	ENOG41069PW	sigma-e factor negative regulatory protein
O23A_p4463	ENOG4105C4S	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity)
O23A_p4464	ENOG4105C3F	Signal peptidase i
O23A_p4467	ENOG41071DT	Involved in DNA repair and RecF pathway recombination (By similarity)
O23A_p4468	ENOG4105CSZ	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate (By similarity)
O23A_p4469	ENOG4108VBV	N-Acetylmuramoyl-L-alanine amidase
O23A_p4470	ENOG4108W15	Protein of unknown function (DUF1456)
O23A_p4471	ENOG4105BZU	Histidine kinase
O23A_p4472	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
O23A_p4473	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
O23A_p4474	ENOG4105DXN	mazG family
O23A_p4475	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
O23A_p4476	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
O23A_p4477	ENOG4105XX3	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity)
O23A_p4478	ENOG4105CE5	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) (By similarity)
O23A_p4479	ENOG4108UH8	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (By similarity)
O23A_p4480	ENOG4106NZV	Responsible for synthesis of pseudouridine from uracil- 13 in transfer RNAs (By similarity)
O23A_p4481	ENOG4105CV2	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates (By similarity)
O23A_p4482	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
O23A_p4483	ENOG4108UM1	dedA family
O23A_p4484	ENOG4108K5P	(LipO)protein
O23A_p4485	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
O23A_p4486	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
O23A_p4487	ENOG4105VCC	30S ribosomal protein S21
O23A_p4488	ENOG4105KTH	gatB Yqey
O23A_p4489	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
O23A_p4490	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
O23A_p4495	ENOG4105C12	Phosphoribosylglycinamide synthetase
O23A_p4496	ENOG4105DC1	bifunctional purine biosynthesis protein purh
O23A_p4499	ENOG4105NAE	bifunctional deaminase-reductase domain protein
O23A_p4500	ENOG4105VCN	Rescues the ribosomes stalled at the 3' end of non-stop mRNAs. May induce hydrolysis of the ribosome-bound peptidyl-tRNA. This activity is crucial when the stalled ribosome can not be rescued by the SsrA(tmRNA)-SmpB quality control system
O23A_p4501	ENOG4105CSA	Coproporphyrinogen iii oxidase
O23A_p4502	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
O23A_p4504	ENOG4105D9R	oxidoreductase
O23A_p4506	ENOG4105D9U	N-acetyltransferase
O23A_p4507	ENOG4105D9U	N-acetyltransferase
O23A_p4509	ENOG4105D4Y	metalloprotease
O23A_p4511	ENOG4105EV4	Multidrug resistance protein mdtH
O23A_p4513	ENOG4105DS2	Anaerobic c4-dicarboxylate transporter
O23A_p4514	ENOG4108IJ0	Aspartate ammonia-lyase
O23A_p4515	ENOG4108YH1	overproduction of this protein in Escherichia coli inhibits the F plasmid-mediated exclusion of bacteriophage T7
O23A_p4517	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
O23A_p4518	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
O23A_p4520	ENOG4105BZU	Histidine kinase
O23A_p4522	ENOG4105D3G	Pseudouridine synthase
O23A_p4523	ENOG4105BZK	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair (By similarity)
O23A_p4525	ENOG410829K	Lysine exporter protein (Lyse ygga)
O23A_p4526	ENOG4105VY0	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters (By similarity)
O23A_p4527	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
O23A_p4530	ENOG4107V40	secretion protein, HlyD family
O23A_p4536	ENOG4105I93	response regulator
O23A_p4537	ENOG4105DUX	Transporter
O23A_p4538	ENOG4105C3Y	UTP-glucose-1-phosphate uridylyltransferase
O23A_p4539	ENOG41083P1	competence protein ComEA helix-hairpin-helix repeat protein
O23A_p4540	ENOG4108RNI	3'(2')5'-bisphosphate nucleotidase
O23A_p4541	ENOG4105K9H	YciI-like protein
O23A_p4542	ENOG4107835	probably involved in intracellular septation (By similarity)
O23A_p4543	ENOG4105DY8	decarboxylase
O23A_p4544	ENOG4108UT2	hemolysin iii
O23A_p4545	ENOG4105D0C	transport protein