locus-tag	class	description
CE463_00040	ENOG4105DH7	May be involved in recombination (By similarity)
CE463_00080	ENOG4105KK6	nuclease
CE463_00085	ENOG4105K70	DNA-binding protein
CE463_00110	ENOG4107QJE	Chromosome Partitioning Protein
CE463_00165	ENOG4105ECI	YeeC-like protein
CE463_00170	ENOG4105F6A	helicase
CE463_00175	ENOG4105D85	methylase
CE463_00190	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
CE463_00265	ENOG4105T95	Thiol disulfide interChange protein
CE463_00330	ENOG4105GMT	ATPase associated with various cellular activities aaa_5
CE463_00395	ENOG4105XPH	Ferredoxin
CE463_00495	ENOG4105M6W	Crispr-associated protein, Csy3 family
CE463_00520	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
CE463_00530	ENOG4108TKH	Nitroreductase
CE463_00535	ENOG4105W8I	Transcriptional regulator
CE463_00640	ENOG4108IYT	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
CE463_00645	ENOG41061P8	Persistence to inhibition of murein or DNA biosynthesis regulatory protein
CE463_00650	ENOG4105CAF	HipA N-terminal domain protein
CE463_00670	ENOG4105I1F	Resistance protein
CE463_00695	ENOG4108VSE	mercuric transport protein
CE463_00710	ENOG4105D13	transposase
CE463_00735	ENOG4108C33	Resolvase
CE463_00740	ENOG4108R0M	Aminoglycoside
CE463_00780	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
CE463_00815	ENOG4108C33	Resolvase
CE463_00855	ENOG4105F2I	Transposase
CE463_00870	ENOG4107W31	Pentapeptide repeat protein
CE463_00970	ENOG4105VUN	Transcriptional regulator
CE463_01040	ENOG4108NVR	Methyl-accepting chemotaxis
CE463_01185	ENOG4107QJE	Chromosome Partitioning Protein
CE463_01205	ENOG4105VXP	Protein of unknown function DUF86
CE463_01210	ENOG4108C33	Resolvase
CE463_01355	ENOG4105MAW	Antitoxin component of a toxin-antitoxin (TA) module. Labile antitoxin that counteracts the effect of the CbtA (YeeV) toxin. It does not bind to the cognate toxin but instead binds to MreB and FtsZ (the toxin targets), enhancing their polymerization by forming higher-order bundles
CE463_01360	ENOG4105F2I	Transposase
CE463_01410	ENOG4105W5Q	DNA repair protein (RadC
CE463_01440	ENOG4107635	Hok Gef family protein
CE463_01465	ENOG4107QJE	Chromosome Partitioning Protein
CE463_01485	ENOG4105C0D	helicase
CE463_01520	ENOG4107SKI	cobyrinic Acid a,c-diamide synthase
CE463_01530	ENOG4105D5G	Transposase
CE463_01555	ENOG4105EQR	Transposase IS116 IS110 IS902
CE463_01560	ENOG4105NHU	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group (By similarity)
CE463_01595	ENOG41066XE	Type III export protein
CE463_01625	ENOG4108KB1	transcriptional regulator, arac family
CE463_01640	ENOG4106V6P	Exoenzyme S synthesis protein C
CE463_01765	ENOG4107U2T	alpha beta
CE463_01775	ENOG4107QJE	Chromosome Partitioning Protein
CE463_01795	ENOG4105F5W	AtP-binding protein
CE463_01930	ENOG4108C33	Resolvase
CE463_01935	ENOG4105VXP	Protein of unknown function DUF86
CE463_02015	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
CE463_02020	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
CE463_02025	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
CE463_02030	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
CE463_02045	ENOG4105D29	Helix-turn-helix type 11 domain protein
CE463_02050	ENOG4108ZNX	Heat shock protein
CE463_02055	ENOG4108ZNX	Heat shock protein
CE463_02070	ENOG4105JKW	Valine--pyruvate aminotransferase
CE463_02085	ENOG4105C2C	drug resistance transporter, Bcr CflA
CE463_02090	ENOG4105EEX	Two component transcriptional regulator (Winged helix family
CE463_02095	ENOG4105C08	Histidine kinase
CE463_02105	ENOG4105C8X	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity)
CE463_02110	ENOG4105D9K	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity)
CE463_02120	ENOG4105DC8	reductase
CE463_02125	ENOG4105BZU	Histidine kinase
CE463_02130	ENOG4105BZS	acriflavin resistance protein
CE463_02135	ENOG410624X	efflux transporter, rnd family, mfp subunit
CE463_02140	ENOG4105EJ2	Transcriptional regulator
CE463_02170	ENOG4105DQF	Hydrolase
CE463_02175	ENOG4108EUD	Lysophospholipase
CE463_02180	ENOG4105FE8	tRNA (Guanosine-2'-O-)-methyltransferase
CE463_02185	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
CE463_02190	ENOG4105VFG	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity)
CE463_02195	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
CE463_02205	ENOG4105DKP	glycosyl transferase, family 9
CE463_02210	ENOG4108W7E	Catalyzes the ATP-dependent phosphorylation of the 3- deoxy-D-manno-octulosonic acid (Kdo) residue in Kdo-lipid IV(A) at the 4-OH position (By similarity)
CE463_02220	ENOG4105EMK	carboxylate amino acid amine transporter
CE463_02250	ENOG4108M6U	Universal stress protein A
CE463_02255	ENOG4105RKW	reductase (By
CE463_02265	ENOG41090A1	ferritin
CE463_02270	ENOG4105CBX	hi0933 family
CE463_02295	ENOG410600T	transposase
CE463_02320	ENOG4105BZU	Histidine kinase
CE463_02330	ENOG4108HRK	Histidine kinase
CE463_02335	ENOG4105DY9	regulatoR
CE463_02340	ENOG4105FCD	Major Facilitator
CE463_02345	ENOG4105CY8	phosphoribosylaminoimidazole carboxylase atpase subunit
CE463_02350	ENOG4108UM6	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity)
CE463_02365	ENOG41063Z6	transcriptional regulator, lysR family
CE463_02370	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
CE463_02375	ENOG4105F03	Provides the (R)-glutamate required for cell wall biosynthesis (By similarity)
CE463_02405	ENOG4105CD5	CoA-binding domain protein
CE463_02420	ENOG4105EMY	transcriptional regulator
CE463_02425	ENOG4105C6M	Alpha-keto-beta-hydroxylacyl reductoisomerase
CE463_02430	ENOG4107QP8	phosphohexose isomerase
CE463_02440	ENOG4105D64	Mechanosensitive ion channel
CE463_02445	ENOG4105EC0	Required for nucleoid occlusion (NO) phenomenon, which prevents Z-ring formation and cell division over the nucleoid. Acts as a DNA-associated cell division inhibitor that binds simultaneously chromosomal DNA and FtsZ, and disrupts the assembly of FtsZ polymers. SlmA-DNA-binding sequences (SBS) are dispersed on non-Ter regions of the chromosome, preventing FtsZ polymerization at these regions (By similarity)
CE463_02450	ENOG4108Z1K	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA (By similarity)
CE463_02455	ENOG4105CJS	Phosphopantothenoylcysteine decarboxylase
CE463_02460	ENOG4105W5Q	DNA repair protein (RadC
CE463_02465	ENOG4105KDC	50s ribosomal protein l28
CE463_02470	ENOG4105W0E	50S ribosomal protein L33
CE463_02480	ENOG4105ERD	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity)
CE463_02485	ENOG4108MJ5	VirK protein
CE463_02490	ENOG4108ZEF	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity)
CE463_02495	ENOG4105M5K	heptosyltransferase
CE463_02500	ENOG4106WTF	Glycosyl transferase, family 2
CE463_02505	ENOG4105XA0	heptosyltransferase ii
CE463_02510	ENOG4105D8A	3-Deoxy-D-manno-octulosonic-acid transferase
CE463_02525	ENOG4106ETB	IIa component
CE463_02530	ENOG4105DIQ	Transcriptional regulator
CE463_02560	ENOG4105X6C	Flagellar basal body-associated protein FliL
CE463_02565	ENOG4105VEI	Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4- hydroxybenzoate (4HB) for the ubiquinone pathway (By similarity)
CE463_02570	ENOG4105C4G	Synthesis of 3-octaprenyl-4-hydroxybenzoate (By similarity)
CE463_02575	ENOG4105E55	glycerol-3-phosphate acyltransferase
CE463_02580	ENOG4105DS7	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity)
CE463_02595	ENOG4107R73	Mate efflux family protein
CE463_02600	ENOG4108UIQ	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity)
CE463_02605	ENOG4105E0F	Histidine kinase
CE463_02610	ENOG4105E3W	Two component transcriptional regulator (Winged helix family
CE463_02620	ENOG4105D7W	serine acetyltransferase
CE463_02630	ENOG41065UX	Non-essential, abundant cell division factor that is required for proper Z-ring formation. It is recruited early to the divisome by direct interaction with FtsZ, stimulating Z-ring assembly and thereby promoting cell division earlier in the cell cycle. Its recruitment to the Z-ring requires functional FtsA or ZipA (By similarity)
CE463_02635	ENOG4108556	Isoprenoid biosynthesis protein with amidotransferase-like domain
CE463_02645	ENOG4105C2M	dna polymerase I
CE463_02650	ENOG4108Z0R	Transferase
CE463_02700	ENOG4105CQ4	Transcriptional regulator
CE463_02705	ENOG4105DHU	Bile acid
CE463_02710	ENOG4105E46	N-alpha,N-alpha,N-alpha-trimethyl-L-histidine metabolic process
CE463_02720	ENOG4105C4W	S-formylglutathione hydrolase
CE463_02730	ENOG4105CC0	LysR family Transcriptional regulator
CE463_02740	ENOG4105UIB	(ABC) transporter
CE463_02745	ENOG4108JQ9	ABC transporter
CE463_02750	ENOG4105DIH	basic membrane
CE463_02755	ENOG4105C4R	Atp-dependent dna helicase
CE463_02795	ENOG4105CUC	YeeE YedE family protein
CE463_02800	ENOG410600T	transposase
CE463_02810	ENOG4107QZF	nitrite reductase NADPH large subunit
CE463_02825	ENOG4105C4N	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis (By similarity)
CE463_02830	ENOG4108R5P	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery (By similarity)
CE463_02840	ENOG4105C75	arginyL-tRNA synthetase
CE463_02850	ENOG4105K6V	RNA polymerase
CE463_02860	ENOG4105DWR	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity)
CE463_02865	ENOG4105CPC	Aldo Keto reductase
CE463_02870	ENOG4105ENN	converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose (By similarity)
CE463_02875	ENOG4105CRD	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P) (By similarity)
CE463_02880	ENOG4105F0Z	galactose-1-phosphate uridylyltransferase
CE463_02885	ENOG4105CMR	udp-glucose 4-epimerase
CE463_02890	ENOG41060NJ	transcriptional regulator
CE463_02895	ENOG4105CNT	hydrolase family 2
CE463_02910	ENOG4108HWV	)-transporter
CE463_02915	ENOG4105C8Q	Methyl-accepting chemotaxis
CE463_02920	ENOG4105D5G	Transposase
CE463_02945	ENOG4105C5B	carbamate kinase
CE463_02950	ENOG4105DBV	ornithine carbamoyltransferase
CE463_02955	ENOG4105CSX	c4-dicarboxylate anaerobic carrier
CE463_02960	ENOG410682Y	Regulates arginine biosynthesis genes (By similarity)
CE463_02965	ENOG4108R9M	Involved in allosteric regulation of aspartate carbamoyltransferase (By similarity)
CE463_02970	ENOG4105CXT	aspartate transcarbamylase
CE463_02985	ENOG4105DJ4	phosphatidylserine decarboxylase
CE463_02990	ENOG4105C8Q	Methyl-accepting chemotaxis
CE463_02995	ENOG4105QNF	Outer membrane lipoprotein
CE463_03005	ENOG4108I6A	alcohol dehydrogenase
CE463_03010	ENOG4108IIE	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
CE463_03015	ENOG4105C15	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
CE463_03025	ENOG4105WWK	YheO domain protein
CE463_03030	ENOG4105CEM	UPF0597 protein
CE463_03040	ENOG4107QMW	pyridine nucleotide-disulfide oxidoreductase
CE463_03045	ENOG4106SNF	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CE463_03050	ENOG4105C34	Pseudouridine synthase
CE463_03055	ENOG4105DBW	Multi-copper polyphenol oxidoreductase laccase
CE463_03060	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
CE463_03065	ENOG4105CU9	asparagine synthetase A
CE463_03070	ENOG4108VVK	transcriptional Regulator, AsnC
CE463_03085	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
CE463_03090	ENOG410642E	Short chain dehydrogenase
CE463_03100	ENOG4107WP9	Histidine kinase
CE463_03110	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
CE463_03115	ENOG4108UQ5	membrane protein YcdZ
CE463_03125	ENOG4105CCD	The exact function is not known. Can catalyze the reduction of a variety of substrates like dimethyl sulfoxide, trimethylamine N-oxide, phenylmethyl sulfoxide and L-methionine sulfoxide. Cannot reduce cyclic N-oxides. Shows no activity as sulfite oxidase (By similarity)
CE463_03130	ENOG4105DQ2	Is probably involved in the electron transfer between its heme and the molybdenum cofactor of the reductase catalytic subunit YedY (By similarity)
CE463_03145	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
CE463_03150	ENOG4105IFJ	Histidine kinase
CE463_03160	ENOG4107QY8	reductase
CE463_03165	ENOG4105CUW	cytochrome C-TYPE protein
CE463_03170	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
CE463_03180	ENOG4107ZYR	domain protein
CE463_03185	ENOG4105D4A	Cell wall formation (By similarity)
CE463_03190	ENOG4105HJX	Biotin- acetyl-CoA-carboxylase ligase
CE463_03210	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
CE463_03220	ENOG4105PM1	preprotein translocase subunit SecE
CE463_03225	ENOG4105E5V	Participates in transcription elongation, termination and antitermination (By similarity)
CE463_03230	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
CE463_03235	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
CE463_03240	ENOG4108VZM	50s ribosomal protein L10
CE463_03245	ENOG4105KBC	Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity)
CE463_03250	ENOG4108IIJ	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
CE463_03255	ENOG4105D27	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
CE463_03260	ENOG4105WWK	YheO domain protein
CE463_03265	ENOG4105KME	endoribonuclease L-psp
CE463_03275	ENOG4108ZKU	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions (By similarity)
CE463_03280	ENOG4105YKK	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions (By similarity)
CE463_03285	ENOG4108UKE	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity)
CE463_03290	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
CE463_03295	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
CE463_03300	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
CE463_03305	ENOG4108ZI0	d,d-heptose 1,7-bisphosphate phosphatase
CE463_03365	ENOG4105EIF	outer membrane protein W
CE463_03385	ENOG4105SYT	Methylenetetrahydrofolate reductase
CE463_03395	ENOG4105DKK	Benzoate
CE463_03400	ENOG4108JCI	Transcriptional regulator
CE463_03440	ENOG4105C7N	Xanthine uracil vitamin C permease
CE463_03445	ENOG4105CMT	Dihydroxyacetone kinase
CE463_03450	ENOG4108UTZ	Dihydroxyacetone kinase
CE463_03455	ENOG4105VDH	Dihydroxyacetone kinase
CE463_03465	ENOG4108JU9	GAF modulated sigma54 specific transcriptional regulator Fis family
CE463_03470	ENOG4105IPI	Membrane
CE463_03500	ENOG4105CH6	catalase
CE463_03505	ENOG4105WCN	acetyltransferase
CE463_03525	ENOG4105BZU	Histidine kinase
CE463_03535	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
CE463_03570	ENOG4105CWB	LysR family transcriptional Regulator
CE463_03580	ENOG4105C2I	pirin domain protein
CE463_03585	ENOG4108VBZ	doxx family
CE463_03590	ENOG4105DSY	exodeoxyribonuclease V, gamma
CE463_03595	ENOG4107QKA	exodeoxyribonuclease V beta
CE463_03600	ENOG4107QYX	exodeoxyribonuclease v alpha
CE463_03620	ENOG4105KHA	Glyoxalase Bleomycin resistance protein (Dioxygenase
CE463_03630	ENOG410600T	transposase
CE463_03650	ENOG4108YZA	Nitrogen regulatory protein pii
CE463_03655	ENOG4105BZU	Histidine kinase
CE463_03670	ENOG4105E0F	Histidine kinase
CE463_03675	ENOG4106TD9	Diguanylate cyclase
CE463_03685	ENOG4105VEQ	Cold shock protein
CE463_03695	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
CE463_03700	ENOG41086KC	Transcriptional regulator
CE463_03705	ENOG4108UUM	single-stranded DNA-binding protein
CE463_03750	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
CE463_03755	ENOG4105VQ0	flagellar hook-basal body complex protein fliE
CE463_03760	ENOG4105C1F	The M ring may be actively involved in energy transduction (By similarity)
CE463_03765	ENOG4105CS3	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
CE463_03775	ENOG4108JIR	Flagellum-specific ATP synthase
CE463_03790	ENOG4105M9M	anti-sigma28 factor FlgM
CE463_03800	ENOG4105K88	Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body (By similarity)
CE463_03805	ENOG4108ZC9	flagellar basal-body rod protein flgc
CE463_03810	ENOG410822I	Flagellar hook capping protein
CE463_03815	ENOG4105BZE	flagellar hook protein, FlgE
CE463_03820	ENOG4108JQA	flagellar
CE463_03825	ENOG4105CGA	flagellar basal-body rod protein FlgG
CE463_03830	ENOG4107W7W	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity)
CE463_03835	ENOG4105D92	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity)
CE463_03845	ENOG4105E1Q	flagellar hook-associated protein
CE463_03865	ENOG4105I03	Flagellin
CE463_03875	ENOG4105I03	Flagellin
CE463_03880	ENOG410804A	Flagellar hook-associated 2 domain-containing protein
CE463_03885	ENOG4105MQ3	flagellar protein FliS
CE463_03910	ENOG4107RD7	Flagellar Motor Protein, MotA
CE463_03915	ENOG4105ER2	Ompa motb domain protein
CE463_03925	ENOG4105E9H	Lytic Murein transglycosylase
CE463_03935	ENOG4108V6E	Cell division protein mraZ
CE463_03940	ENOG4105CGJ	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity)
CE463_03945	ENOG41063Y6	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity)
CE463_03950	ENOG4105CJN	penicillin-binding protein
CE463_03955	ENOG4107EEN	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity)
CE463_03960	ENOG4108EQQ	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein (By similarity)
CE463_03965	ENOG4105CPY	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity)
CE463_03970	ENOG4105DMZ	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity)
CE463_03975	ENOG4105CNI	cell division protein FtsW
CE463_03980	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
CE463_03985	ENOG4105DFU	Cell wall formation (By similarity)
CE463_03990	ENOG4105K7E	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly (By similarity)
CE463_03995	ENOG4105CIT	This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity)
CE463_04000	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
CE463_04005	ENOG4105C7C	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
CE463_04015	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
CE463_04025	ENOG4105M6F	mutator MutT protein
CE463_04030	ENOG41067SF	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase (By similarity)
CE463_04035	ENOG4105DHA	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity (By similarity)
CE463_04045	ENOG4105EHH	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue (By similarity)
CE463_04055	ENOG4107QHF	type ii secretion system protein e
CE463_04075	ENOG4105D18	nicotinate-nucleotide pyrophosphorylase
CE463_04090	ENOG41073TP	transcriptional regulator
CE463_04095	ENOG4105DAQ	Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) (By similarity)
CE463_04100	ENOG4107QSN	dihydrolipoamide acetyltransferase
CE463_04105	ENOG4107QN2	dihydrolipoyl dehydrogenase
CE463_04110	ENOG4105BZU	Histidine kinase
CE463_04120	ENOG4108N3W	hemolysin secretion protein
CE463_04125	ENOG4108N3W	hemolysin secretion protein
CE463_04135	ENOG4107QIJ	Aconitate hydratase 2
CE463_04140	ENOG4105BZU	Histidine kinase
CE463_04145	ENOG4105F6U	Short-chain dehydrogenase reductase Sdr
CE463_04150	ENOG4105HEI	LysR family (Transcriptional regulator
CE463_04155	ENOG4108MGI	Transcriptional regulator
CE463_04160	ENOG4105E82	cytochrome subunit of dehydrogenase
CE463_04170	ENOG4105CKI	cobalamin synthesis protein
CE463_04185	ENOG4105K8U	2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
CE463_04190	ENOG4107ZVW	dihydroneopterin aldolase
CE463_04195	ENOG4105K7Z	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP (By similarity)
CE463_04325	ENOG4105DWD	nucleoside recognition domain protein
CE463_04335	ENOG4107R88	Chemotaxis protein (CheV)
CE463_04340	ENOG410904N	short-chain dehydrogenase reductase
CE463_04345	ENOG4105E0I	Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of tRNA(Met), by using acetyl-CoA as an acetyl donor and ATP (or GTP) (By similarity)
CE463_04360	ENOG4108UQY	Iron-storage protein
CE463_04370	ENOG4108Z5K	methylglyoxal synthase
CE463_04385	ENOG4105HDK	L-asparaginase
CE463_04395	ENOG4105DDV	Transcriptional regulator (LacI family
CE463_04405	ENOG4105DKQ	ROK family
CE463_04410	ENOG4105VCP	PTS System
CE463_04415	ENOG4105CS2	ec 3.2.1.21
CE463_04425	ENOG4105VZJ	PTS System
CE463_04430	ENOG4105CK1	PTS System
CE463_04440	ENOG4105D4X	repressor
CE463_04445	ENOG4105C5Y	PTS System
CE463_04450	ENOG4105CG3	alpha amylase, catalytic region
CE463_04455	ENOG4108UW5	maltose o-acetyltransferase
CE463_04465	ENOG4105DFD	Na H antiporter
CE463_04500	ENOG4105CXW	Synthesizes alpha-1,4-glucan chains using ADP-glucose (By similarity)
CE463_04505	ENOG4107QQ4	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans (By similarity)
CE463_04510	ENOG4105D8J	Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle (By similarity)
CE463_04515	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
CE463_04530	ENOG4107VXZ	Hydrolase
CE463_04535	ENOG4105KW8	RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity)
CE463_04540	ENOG4105F1S	paraquat-inducible protein a
CE463_04545	ENOG4105DY2	Paraquat-inducible protein b
CE463_04550	ENOG4108Q2G	(LipO)protein
CE463_04555	ENOG4105UYK	outer membrane protein a
CE463_04570	ENOG4105H4F	exported protein
CE463_04580	ENOG4105KMG	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes (By similarity)
CE463_04585	ENOG4105CEN	a g-specific adenine glycosylase
CE463_04600	ENOG4105D4J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
CE463_04605	ENOG4105CJ3	phosphate transporter
CE463_04610	ENOG4107IX6	phosphate transport regulator
CE463_04625	ENOG4105D1S	lipid A biosynthesis
CE463_04630	ENOG4105DW0	Catalyzes the ADP transfer to D-glycero-D-manno-heptose 1-phosphate, yielding ADP-D,D-heptose (By similarity)
CE463_04635	ENOG4105DFG	type I secretion outer membrane protein
CE463_04640	ENOG41087AY	ADP-Ribose pyrophosphatase
CE463_04645	ENOG4108SX3	cytoplasmic protein
CE463_04650	ENOG41070EG	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes (By similarity)
CE463_04655	ENOG4105IPS	esterase
CE463_04670	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
CE463_04675	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
CE463_04735	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
CE463_04765	ENOG4107S7E	1-acyl-sn-glycerol-3-phosphate acyltransferase
CE463_04785	ENOG41082IR	Excinuclease ABC C subunit domain protein
CE463_04800	ENOG4108RG0	uracil-dna glycosylase
CE463_04810	ENOG4105ETT	transcriptional Regulator, LysR family
CE463_04815	ENOG4105FAV	ABC, transporter
CE463_04820	ENOG4105FDK	ABC transporter
CE463_04825	ENOG4105NXV	High-affinity zinc uptake system protein
CE463_04845	ENOG4105DR5	peptidase
CE463_04855	ENOG4105R2J	Conserved Protein
CE463_04875	ENOG4105D86	that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity)
CE463_04895	ENOG4105D6J	arsenicaL-resistance protein
CE463_04900	ENOG4105K89	arsenate reductase
CE463_04910	ENOG4105H3G	oxidoreductase
CE463_04920	ENOG4105CCA	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle (By similarity)
CE463_04930	ENOG4105C0N	N-acetylglutamate semialdehyde dehydrogenase
CE463_04935	ENOG4105CAS	nag kinase
CE463_04945	ENOG4105CDH	Citrulline--aspartate ligase
CE463_04950	ENOG4105CH7	arginosuccinase
CE463_04955	ENOG4107NQ8	LysR family Transcriptional regulator
CE463_04965	ENOG41090U3	tautomerase
CE463_04995	ENOG4108UW5	maltose o-acetyltransferase
CE463_05000	ENOG4107PU6	Membrane
CE463_05005	ENOG4105DE7	Sulfate ABC transporter periplasmic sulfate-binding protein
CE463_05015	ENOG4108I5D	sulfate abc transporter
CE463_05025	ENOG4105ECW	sulfate abc transporter
CE463_05030	ENOG4108IJ6	ABC transporter
CE463_05035	ENOG4107R11	Transcriptional regulator
CE463_05040	ENOG4108IYI	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine (By similarity)
CE463_05045	ENOG4105E5Q	amino acid AbC transporter
CE463_05055	ENOG4105CDA	abc transporter atp-binding protein
CE463_05060	ENOG4105CT1	(ABC) transporter
CE463_05065	ENOG4108M1A	Chitin-binding protein
CE463_05105	ENOG4107BJW	polysaccharide deacetylase
CE463_05110	ENOG4105CND	Glycosyl transferase, family 2
CE463_05155	ENOG4105G0K	glycine radical enzyme YjjI family
CE463_05160	ENOG41076CZ	activating enzyme
CE463_05180	ENOG4105CGF	Aromatic amino acid aminotransferase
CE463_05210	ENOG4108V1J	Has antioxidant activity. Could remove peroxides or H(2)O(2) (By similarity)
CE463_05220	ENOG4105C1J	atp-dependent rna helicase
CE463_05240	ENOG4107RHT	methyl-accepting chemotaxis sensory transducer with Pas Pac sensor
CE463_05255	ENOG4105XTV	UPF0231 protein
CE463_05260	ENOG4108IXP	Carbohydrate diacid transcriptional activator CdaR
CE463_05265	ENOG4107QQ0	gntp family
CE463_05270	ENOG4105BZW	Glycerate kinase
CE463_05285	ENOG4105JQN	Transcriptional regulator
CE463_05290	ENOG4105D9N	nucleoside
CE463_05300	ENOG4108YZN	class I peptide chain release factor
CE463_05305	ENOG4108YZA	Nitrogen regulatory protein pii
CE463_05320	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
CE463_05325	ENOG4105EZR	dyp-type peroxidase family protein
CE463_05330	ENOG410682Y	Regulates arginine biosynthesis genes (By similarity)
CE463_05335	ENOG4105E5Z	arginine transporter ATP-binding subunit
CE463_05340	ENOG4106PMH	Extracellular solute-binding protein family 3
CE463_05345	ENOG4105GBT	ABC transporter
CE463_05350	ENOG4105DMR	ABC, transporter
CE463_05355	ENOG4105C80	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
CE463_05360	ENOG4108UV7	flagellar protein motX
CE463_05365	ENOG4108EGH	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity)
CE463_05370	ENOG4105KPV	Transcriptional regulator
CE463_05375	ENOG4108JU6	CBS domain protein
CE463_05380	ENOG4106KVJ	cytochrome C assembly protein
CE463_05385	ENOG4105CB9	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
CE463_05390	ENOG4105K5M	30s ribosomal protein S16
CE463_05395	ENOG4108ZR6	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity)
CE463_05400	ENOG4105D6X	Specifically methylates guanosine-37 in various tRNAs (By similarity)
CE463_05405	ENOG4108YY1	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity)
CE463_05415	ENOG4105IRT	Sequence-specific endonuclease that cleaves unmethylated GATC sequences. It is involved in DNA mismatch repair (By similarity)
CE463_05420	ENOG4105EJF	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity)
CE463_05425	ENOG4108HRM	phosphoenolpyruvate--protein phosphotransferase
CE463_05430	ENOG4105C3B	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity)
CE463_05435	ENOG4105C0V	Provides the sole de novo source of dTMP for DNA biosynthesis (By similarity)
CE463_05440	ENOG4105DRC	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity)
CE463_05450	ENOG41063Z6	transcriptional regulator, lysR family
CE463_05455	ENOG41080HT	Transcriptional regulator, arsr family
CE463_05460	ENOG4105KQV	Binds directly to 16S ribosomal RNA (By similarity)
CE463_05465	ENOG4105CJR	Integral membrane protein (MviN
CE463_05470	ENOG4105DTN	riboflavin biosynthesis protein ribF
CE463_05475	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
CE463_05480	ENOG4105M02	This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity)
CE463_05485	ENOG41090X3	Peptidyl-prolyl cis-trans isomerase
CE463_05490	ENOG4105C48	Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) (By similarity)
CE463_05495	ENOG4106855	Competence protein
CE463_05530	ENOG4105C4K	Nad synthetase
CE463_05535	ENOG4108YZA	Nitrogen regulatory protein pii
CE463_05545	ENOG4106762	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD) (By similarity)
CE463_05550	ENOG4106TD9	Diguanylate cyclase
CE463_05555	ENOG4105C40	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity)
CE463_05560	ENOG4105C2N	RNA methyltransferase TrmH family group 3
CE463_05590	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
CE463_05595	ENOG4105C56	H( )-stimulated, divalent metal cation uptake system (By similarity)
CE463_05600	ENOG4108ZDX	Binds together with S18 to 16S ribosomal RNA (By similarity)
CE463_05605	ENOG4105VH8	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity)
CE463_05610	ENOG4105K9Q	Binds to the 23S rRNA (By similarity)
CE463_05615	ENOG4105DP0	ferredoxin-NADP reductase
CE463_05640	ENOG4105DQ4	alcohol dehydrogenase
CE463_05645	ENOG4105W39	Membrane
CE463_05655	ENOG4105D9M	gamma-glutamylcysteine synthetase
CE463_05665	ENOG4108IQE	Amp-dependent synthetase and ligase
CE463_05675	ENOG4108RTV	Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol (By similarity)
CE463_05685	ENOG4107R4Q	Functions as an ATPase. May play a role in metal insertion (metal-chelatase) or as a chaperone (By similarity)
CE463_05690	ENOG4105EV2	VWA domain protein interacting with AAA ATPase
CE463_05700	ENOG4105EW9	transcriptional regulator AsnC family
CE463_05710	ENOG4105BZU	Histidine kinase
CE463_05715	ENOG4105C8A	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP (By similarity)
CE463_05720	ENOG4108MJ3	acetyltransferase
CE463_05725	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
CE463_05735	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
CE463_05745	ENOG4105KA4	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity)
CE463_05750	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
CE463_05755	ENOG4105C4M	(Ubiquinol oxidase) subunit I
CE463_05760	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
CE463_05770	ENOG4105KJB	cyd operon protein YbgE
CE463_05775	ENOG4107YD3	Thioesterase
CE463_05780	ENOG4105E02	MotA TolQ exbB proton channel
CE463_05785	ENOG4105M8F	Biopolymer transport protein exbD tolR
CE463_05795	ENOG4107R6Y	Involved in the TonB-independent uptake of proteins (By similarity)
CE463_05800	ENOG4105KCK	Peptidoglycan-associated lipoprotein
CE463_05805	ENOG4105UFD	tol-pal system protein YbgF
CE463_05870	ENOG4105C8Q	Methyl-accepting chemotaxis
CE463_05875	ENOG4105D0I	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate (By similarity)
CE463_05880	ENOG4105DSB	aldose 1-epimerase
CE463_05885	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
CE463_05890	ENOG4107RTM	4-alpha-glucanotransferase (EC 2.4.1.25)
CE463_05895	ENOG4105C9C	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity)
CE463_05905	ENOG4105E0X	reductase
CE463_05915	ENOG4105EYW	Ion transport protein
CE463_05920	ENOG4106MWK	domain protein
CE463_05925	ENOG4105C26	Dehydrogenase
CE463_05930	ENOG4105E09	nadh pyrophosphatase
CE463_05935	ENOG4105CFZ	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III (By similarity)
CE463_05940	ENOG4105F0N	pyrophosphate phospho-hydrolase
CE463_05945	ENOG4105DFU	Cell wall formation (By similarity)
CE463_05950	ENOG4108UMA	3-octaprenyl-4-hydroxybenzoate carboxy-lyase
CE463_05955	ENOG410630P	Transcriptional regulator
CE463_05960	ENOG4108UGV	hypoxanthine phosphoribosyltransferase
CE463_05965	ENOG4105DA5	(ABC) transporter
CE463_05970	ENOG4105E3A	(ABC) transporter
CE463_05980	ENOG4108IAA	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate (By similarity)
CE463_05985	ENOG4105CCG	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is tranferred onto alpha-ketoisovalerate to form ketopantoate (By similarity)
CE463_05990	ENOG4105K8U	2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
CE463_05995	ENOG4105DJ0	Poly(A) Polymerase
CE463_06000	ENOG4106F3G	Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon (By similarity)
CE463_06005	ENOG4108V7X	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
CE463_06010	ENOG4105PW4	Sugar fermentation stimulation protein homolog
CE463_06020	ENOG4105CQ7	ATP-dependent helicase
CE463_06025	ENOG4105BZ4	penicillin-binding protein
CE463_06030	ENOG4108YZK	glyoxalase bleomycin resistance protein dioxygenase
CE463_06035	ENOG4108ZBZ	Catalyzes the excretion of spermidine (By similarity)
CE463_06040	ENOG41090TI	Catalyzes the excretion of spermidine (By similarity)
CE463_06045	ENOG4105CWB	LysR family transcriptional Regulator
CE463_06050	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
CE463_06060	ENOG41076MN	Phosphoesterase, PA-phosphatase related
CE463_06075	ENOG4105CDM	Glutamate-1-semialdehyde aminotransferase
CE463_06080	ENOG4105CMQ	Chloride channel
CE463_06090	ENOG4108YX9	iron--sulfur cluster insertion protein erpA
CE463_06120	ENOG4105E09	nadh pyrophosphatase
CE463_06125	ENOG4105E0F	Histidine kinase
CE463_06130	ENOG4105E3W	Two component transcriptional regulator (Winged helix family
CE463_06135	ENOG4105DJY	efflux transporter, rnd family, mfp subunit
CE463_06155	ENOG4108GAE	asmA family
CE463_06165	ENOG4105CYX	Short-chain dehydrogenase reductase Sdr
CE463_06200	ENOG410804X	Transcriptional regulator
CE463_06205	ENOG4105CE6	Adenylation and deadenylation of glutamate--ammonia ligase (By similarity)
CE463_06225	ENOG4105CJH	Alcohol dehydrogenase zinc-binding domain protein
CE463_06230	ENOG4108ZHJ	Organic hydroperoxide resistance protein
CE463_06235	ENOG4105K56	Transcriptional regulator
CE463_06250	ENOG4105EW9	transcriptional regulator AsnC family
CE463_06265	ENOG4108K4B	hydrolase
CE463_06280	ENOG4105C8J	)-transporter
CE463_06290	ENOG4105C8J	)-transporter
CE463_06315	ENOG4107SQD	Transcriptional regulator, GntR family
CE463_06340	ENOG4105XEP	YhcH YjgK YiaL family protein
CE463_06350	ENOG4105CUY	Mechanosensitive ion channel
CE463_06355	ENOG4107N1Q	ErfK YbiS YcfS YnhG family protein
CE463_06360	ENOG4105CK7	Sodium proline symporter
CE463_06395	ENOG4105D6S	protein involved in catabolism of external DNA
CE463_06405	ENOG4105C5H	ABC transporter
CE463_06410	ENOG4105C2X	Arabinose 5-phosphate isomerase
CE463_06415	ENOG4105G5H	Membrane
CE463_06420	ENOG4107QX8	SPFH domain, Band 7 family protein
CE463_06425	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
CE463_06430	ENOG4105C11	sulfate adenylyltransferase), subunit 2
CE463_06435	ENOG4105C3T	may be the GTPase, regulating ATP sulfurylase activity (By similarity)
CE463_06445	ENOG4108I67	Catalyzes the synthesis of activated sulfate (By similarity)
CE463_06450	ENOG410600T	transposase
CE463_06515	ENOG4108UUE	Transcriptional regulator
CE463_06540	ENOG4105DKQ	ROK family
CE463_06545	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
CE463_06550	ENOG4105BZA	Phosphoglycerate kinase
CE463_06555	ENOG4105D2N	Aldolase
CE463_06560	ENOG4105CJP	fad dependent oxidoreductase
CE463_06575	ENOG4105VF7	tolerance protein
CE463_06610	ENOG4108IYU	L-aspartate oxidase
CE463_06615	ENOG4105EMN	RNA polymerase sigma factor
CE463_06620	ENOG41069PW	sigma-e factor negative regulatory protein
CE463_06635	ENOG4105C4S	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity)
CE463_06640	ENOG4105C3F	Signal peptidase i
CE463_06655	ENOG41071DT	Involved in DNA repair and RecF pathway recombination (By similarity)
CE463_06660	ENOG4105CSZ	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate (By similarity)
CE463_06665	ENOG4108VBV	N-Acetylmuramoyl-L-alanine amidase
CE463_06670	ENOG4108W15	Protein of unknown function (DUF1456)
CE463_06675	ENOG4105BZU	Histidine kinase
CE463_06680	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
CE463_06685	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
CE463_06690	ENOG4105DXN	mazG family
CE463_06695	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
CE463_06700	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
CE463_06705	ENOG4105XX3	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity)
CE463_06710	ENOG4105CE5	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) (By similarity)
CE463_06715	ENOG4108UH8	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (By similarity)
CE463_06720	ENOG4106NZV	Responsible for synthesis of pseudouridine from uracil- 13 in transfer RNAs (By similarity)
CE463_06725	ENOG4105CV2	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates (By similarity)
CE463_06730	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
CE463_06735	ENOG4108UM1	dedA family
CE463_06740	ENOG4108K5P	(LipO)protein
CE463_06745	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
CE463_06750	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
CE463_06755	ENOG4105VCC	30S ribosomal protein S21
CE463_06760	ENOG4105KTH	gatB Yqey
CE463_06765	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
CE463_06770	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
CE463_06810	ENOG4105C12	Phosphoribosylglycinamide synthetase
CE463_06815	ENOG4105DC1	bifunctional purine biosynthesis protein purh
CE463_06825	ENOG4105NAE	bifunctional deaminase-reductase domain protein
CE463_06830	ENOG4105VCN	Rescues the ribosomes stalled at the 3' end of non-stop mRNAs. May induce hydrolysis of the ribosome-bound peptidyl-tRNA. This activity is crucial when the stalled ribosome can not be rescued by the SsrA(tmRNA)-SmpB quality control system
CE463_06835	ENOG4105CSA	Coproporphyrinogen iii oxidase
CE463_06840	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
CE463_06850	ENOG4105D9R	oxidoreductase
CE463_06860	ENOG4105D9U	N-acetyltransferase
CE463_06870	ENOG4105D4Y	metalloprotease
CE463_06880	ENOG4105EV4	Multidrug resistance protein mdtH
CE463_06890	ENOG4105DS2	Anaerobic c4-dicarboxylate transporter
CE463_06895	ENOG4108IJ0	Aspartate ammonia-lyase
CE463_06900	ENOG4108YH1	overproduction of this protein in Escherichia coli inhibits the F plasmid-mediated exclusion of bacteriophage T7
CE463_06910	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
CE463_06915	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
CE463_06925	ENOG4105BZU	Histidine kinase
CE463_06935	ENOG4105D3G	Pseudouridine synthase
CE463_06940	ENOG4105BZK	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair (By similarity)
CE463_06970	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
CE463_06980	ENOG4108IAB	Phoh family
CE463_06985	ENOG4107T0D	ABC, transporter
CE463_06990	ENOG4106SMU	thiamine transporter membrane protein
CE463_06995	ENOG4105DP9	ABC transporter
CE463_07010	ENOG4105MQS	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
CE463_07015	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
CE463_07020	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
CE463_07025	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
CE463_07035	ENOG4105YVM	Phosphoesterase, PA-phosphatase related
CE463_07050	ENOG4105C7K	acetolactate synthase
CE463_07055	ENOG4108ZP8	Acetolactate synthase small subunit
CE463_07060	ENOG4105C6K	Malic enzyme
CE463_07065	ENOG4105C6H	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity)
CE463_07070	ENOG4105PQ6	UPF0208 membrane protein
CE463_07075	ENOG4105XWI	UPF0304 protein
CE463_07080	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
CE463_07085	ENOG4105RH4	Glycine cleavage system transcriptional repressor
CE463_07090	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
CE463_07095	ENOG4107EG0	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
CE463_07100	ENOG4107QWK	SAICAR synthetase
CE463_07110	ENOG4105EXG	Transcriptional regulator
CE463_07135	ENOG4105BZU	Histidine kinase
CE463_07155	ENOG4105BZU	Histidine kinase
CE463_07160	ENOG4108N3W	hemolysin secretion protein
CE463_07165	ENOG4105MDZ	Transcriptional activator rfaH
CE463_07170	ENOG4105D01	(LipO)protein
CE463_07175	ENOG4108UMI	ABC transporter, permease
CE463_07200	ENOG4105DR1	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)
CE463_07205	ENOG4105K8N	protein family UPF0079, ATPase
CE463_07210	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
CE463_07215	ENOG4105DC6	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity)
CE463_07220	ENOG4105DKX	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity)
CE463_07225	ENOG4105KW8	RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity)
CE463_07230	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
CE463_07235	ENOG4107QJR	hflk protein
CE463_07240	ENOG4105EPW	hflc protein
CE463_07250	ENOG4105EAH	synthase
CE463_07255	ENOG4105KK9	This protein binds to 23S rRNA in the presence of protein L20 (By similarity)
CE463_07260	ENOG4105K46	50S ribosomal protein l27
CE463_07265	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
CE463_07270	ENOG4105DWD	nucleoside recognition domain protein
CE463_07275	ENOG4105CEY	Amp-dependent synthetase and ligase
CE463_07295	ENOG4105DEN	Luciferase family
CE463_07310	ENOG4105DDT	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP (By similarity)
CE463_07315	ENOG4105NWN	ApaG protein
CE463_07320	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
CE463_07325	ENOG4105CEZ	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) (By similarity)
CE463_07335	ENOG4105E7H	involved in the assembly of LPS in the outer leaflet of the outer membrane. Determines N-hexane tolerance and is involved in outer membrane permeability. Essential for envelope biogenesis (By similarity)
CE463_07340	ENOG4105EHM	Aminoglycoside phosphotransferase
CE463_07345	ENOG4108S0S	Nucleotidyl transferase
CE463_07350	ENOG41066UG	Regulatory DnaK co-chaperone. Direct interaction between DnaK and DjlA is needed for the induction of the wcaABCDE operon, involved in the synthesis of a colanic acid polysaccharide capsule, possibly through activation of the RcsB RcsC phosphotransfer signaling pathway. The colanic acid capsule may help the bacterium survive conditions outside the host (By similarity)
CE463_07355	ENOG4105C7N	Xanthine uracil vitamin C permease
CE463_07365	ENOG4105C5H	ABC transporter
CE463_07390	ENOG4105EHG	Permease protein
CE463_07400	ENOG41090JE	Utilization Protein
CE463_07405	ENOG4105PYN	Pyridoxamine 5-phosphate oxidase-related
CE463_07425	ENOG4105D05	Receptor
CE463_07430	ENOG4105D8G	Major Facilitator superfamily
CE463_07440	ENOG4105VMP	Transcriptional regulator
CE463_07470	ENOG4108MA4	Peptidase M66
CE463_07475	ENOG4108M1A	Chitin-binding protein
CE463_07485	ENOG4107RYR	Transcriptional regulator, Crp Fnr family
CE463_07490	ENOG4108UKZ	OsmC family
CE463_07505	ENOG4105CJE	phosphoribulokinase (EC 2.7.1.19)
CE463_07515	ENOG41060GT	Translocates 4-amino-4-deoxy-L-arabinose- phosphoundecaprenol (alpha-L-Ara4N-phosphoundecaprenol) from the cytoplasmic to the periplasmic side of the inner membrane (By similarity)
CE463_07520	ENOG4105SA9	Catalyzes the transfer of the L-Ara4N moiety of the glycolipid undecaprenyl phosphate-alpha-L-Ara4N to lipid A. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides (By similarity)
CE463_07525	ENOG4105F73	Catalyzes the deformylation of 4-deoxy-4-formamido-L- arabinose-phosphoundecaprenol to 4-amino-4-deoxy-L-arabinose- phosphoundecaprenol. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides (By similarity)
CE463_07535	ENOG4105CKK	Glycosyl transferase, family 2
CE463_07540	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
CE463_07550	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
CE463_07555	ENOG4105C6Y	Udp-glucose 6-dehydrogenase
CE463_07560	ENOG4105YP7	UPF0270 protein
CE463_07570	ENOG4105DNZ	Alpha Beta Hydrolase
CE463_07575	ENOG4107R88	Chemotaxis protein (CheV)
CE463_07585	ENOG4105VKU	nucleicacid-binding protein
CE463_07590	ENOG4108YZY	peptidylprolyl cis-trans isomerase
CE463_07595	ENOG4105VRX	Protein slyX homolog
CE463_07605	ENOG4108V1T	peptidylprolyl cis-trans isomerase
CE463_07610	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
CE463_07630	ENOG4105CGH	5'-nucleotidase
CE463_07635	ENOG4105BZU	Histidine kinase
CE463_07650	ENOG4105CDU	Replicative dna helicase
CE463_07655	ENOG4105CDU	Replicative dna helicase
CE463_07660	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
CE463_07665	ENOG4105K5D	4fe-4S ferredoxin iroN-sulfur binding
CE463_07670	ENOG4105CFP	Peptidase U32
CE463_07675	ENOG4108NJZ	Sensory box GGDEF EAL domain protein
CE463_07690	ENOG4105BZU	Histidine kinase
CE463_07720	ENOG4105C9B	Cysteine desulfurase
CE463_07725	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
CE463_07760	ENOG4105D5G	Transposase
CE463_07775	ENOG4105Q26	Siderophore-interacting protein
CE463_07780	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
CE463_07785	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
CE463_07790	ENOG4105DJY	efflux transporter, rnd family, mfp subunit
CE463_07800	ENOG4105E2M	Manganese-dependent inorganic pyrophosphatase
CE463_07805	ENOG4105C4F	May be involved in recombinational repair of damaged DNA (By similarity)
CE463_07810	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
CE463_07815	ENOG4105K90	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
CE463_07820	ENOG4105CFG	Acts as a chaperone (By similarity)
CE463_07825	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
CE463_07835	ENOG4105D7K	pfkb domain protein
CE463_07845	ENOG4108HKT	sucrose-6-phosphate hydrolase
CE463_07850	ENOG4105WBN	Transcriptional regulator (LacI family
CE463_07870	ENOG41080HT	Transcriptional regulator, arsr family
CE463_07900	ENOG4105BZU	Histidine kinase
CE463_07905	ENOG4107RMF	Catalyzes both the ATP-dependent activation of exogenously supplied lipoate to lipoyl-AMP and the transfer of the activated lipoyl onto the lipoyl domains of lipoate-dependent enzymes (By similarity)
CE463_07945	ENOG4105CGK	Exodeoxyribonuclease III
CE463_08005	ENOG4107RDB	Major Facilitator
CE463_08010	ENOG4105F1R	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group (By similarity)
CE463_08020	ENOG4105BZ9	Cytochrome C oxidase, subunit I
CE463_08025	ENOG4105E2S	oxidase) subunit II
CE463_08060	ENOG4107P2S	Transcriptional regulator
CE463_08065	ENOG4105CI1	PTS System
CE463_08085	ENOG410600T	transposase
CE463_08100	ENOG4105DM4	PTS System
CE463_08110	ENOG4105EIP	mannose-6-phosphate isomerase
CE463_08115	ENOG4106R3P	AraC family transcriptional regulator
CE463_08120	ENOG4108HMX	isocitrate dehydrogenase (NADP)
CE463_08165	ENOG4105DFP	Integrase
CE463_08175	ENOG4108UH4	Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity)
CE463_08180	ENOG4108Z1B	Cyclase dehydrase
CE463_08185	ENOG4105VDB	UPF0125 protein
CE463_08190	ENOG4105K4T	epimerase
CE463_08195	ENOG4105YRI	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
CE463_08235	ENOG4107U53	septum site-determining protein minD
CE463_08275	ENOG4105C0A	alcohol dehydrogenase
CE463_08280	ENOG4107SXA	Phosphorylase
CE463_08285	ENOG4105D3G	Pseudouridine synthase
CE463_08290	ENOG4105DU0	nucleoside hydrolase
CE463_08305	ENOG4105RX8	Protein of unknown function (DUF1523)
CE463_08310	ENOG4108N3W	hemolysin secretion protein
CE463_08315	ENOG410829K	Lysine exporter protein (Lyse ygga)
CE463_08325	ENOG410600T	transposase
CE463_08330	ENOG4108KDD	Involved in the transport of maltose and maltodextrins (By similarity)
CE463_08335	ENOG4107W52	maltose operon periplasmic protein
CE463_08340	ENOG4105CI1	PTS System
CE463_08345	ENOG4108T8E	UPF0325 protein
CE463_08350	ENOG4105DMJ	Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate (By similarity)
CE463_08360	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
CE463_08365	ENOG4105CE9	30S ribosomal protein S2
CE463_08370	ENOG4105CU7	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity)
CE463_08375	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
CE463_08380	ENOG4108VCV	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity)
CE463_08385	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
CE463_08390	ENOG4105KNE	Phosphatidate cytidylyltransferase
CE463_08395	ENOG4105CEA	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity)
CE463_08400	ENOG4105DZP	Membrane-associated zinc metalloprotease
CE463_08410	ENOG4108RFI	Molecular chaperone that interacts specifically with outer membrane proteins, thus maintaining the solubility of early folding intermediates during passage through the periplasm (By similarity)
CE463_08415	ENOG4105D7M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
CE463_08420	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
CE463_08425	ENOG4105DAF	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
CE463_08430	ENOG4105D0V	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
CE463_08435	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
CE463_08440	ENOG4105C0B	DNA polymerase III (alpha subunit)
CE463_08445	ENOG4107QM9	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA (By similarity)
CE463_08450	ENOG4108M3R	transcriptional activator CadC
CE463_08455	ENOG4105D5Q	Arginine ornithine antiporter
CE463_08460	ENOG4105CXN	decarboxylase
CE463_08465	ENOG4107XGF	functions in a salvage pathway. Uses pyridoxamine (By similarity)
CE463_08475	ENOG4105EQ2	LysR family Transcriptional regulator
CE463_08480	ENOG4105C44	Serine transporter
CE463_08485	ENOG4105DVH	amino acid
CE463_08490	ENOG4105KNA	-acetyltransferase
CE463_08495	ENOG4105C5H	ABC transporter
CE463_08505	ENOG4105C9K	Endothelin-converting enzyme 1
CE463_08510	ENOG4105D3U	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
CE463_08515	ENOG4105BZU	Histidine kinase
CE463_08550	ENOG4107T9C	Alpha amylase catalytic region
CE463_08560	ENOG4108V1U	phospholipid-binding protein
CE463_08565	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
CE463_08580	ENOG4105C87	Aminotransferase class I and II
CE463_08590	ENOG4105C5Q	Transcriptional regulator
CE463_08595	ENOG4105UBK	short-chain dehydrogenase reductase
CE463_08600	ENOG4105ERU	peptidase
CE463_08605	ENOG4105EY2	Catalyzes the hydrolysis of N(2)-succinylarginine into N(2)-succinylornithine, ammonia and CO(2) (By similarity)
CE463_08610	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
CE463_08620	ENOG4107RHT	methyl-accepting chemotaxis sensory transducer with Pas Pac sensor
CE463_08625	ENOG4105E2D	ec 3.2.1.52
CE463_08630	ENOG4105RD7	BadF BadG BcrA BcrD
CE463_08640	ENOG4108JQ7	(ABC) transporter
CE463_08650	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
CE463_08685	ENOG4105XIQ	Protein of unknown function (DUF2517)
CE463_08695	ENOG4107SDU	Methyl-accepting chemotaxis
CE463_08700	ENOG4108ESY	Metal dependent phosphohydrolase
CE463_08705	ENOG4105DR8	Membrane
CE463_08710	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
CE463_08715	ENOG4105C6R	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor (By similarity)
CE463_08720	ENOG4108IUZ	ABC transporter
CE463_08725	ENOG4107A5B	Binding-protein-dependent transport systems, inner membrane component
CE463_08740	ENOG4105BZU	Histidine kinase
CE463_08750	ENOG4107H9G	Necessary for formate dehydrogenase activity (By similarity)
CE463_08765	ENOG410600T	transposase
CE463_08795	ENOG410600T	transposase
CE463_08825	ENOG4108IEG	Formate dehydrogenase Alpha subunit
CE463_08830	ENOG4105QAX	Iron-sulfur
CE463_08845	ENOG4107R1I	NAD-dependent malic enzyme
CE463_08850	ENOG4105C2W	permease
CE463_08855	ENOG4106TNF	Periplasmic binding protein
CE463_08875	ENOG4107R1I	NAD-dependent malic enzyme
CE463_08880	ENOG4105CEQ	signal transduction histidine kinase regulating citrate malate metabolism
CE463_08885	ENOG4106YYS	transcriptional regulatory protein
CE463_08895	ENOG4105CPC	Aldo Keto reductase
CE463_08905	ENOG4108IPJ	Membrane
CE463_08915	ENOG4105JQN	Transcriptional regulator
CE463_08925	ENOG4107YUH	hydrolase
CE463_08935	ENOG4105C26	Dehydrogenase
CE463_08940	ENOG4108JU9	GAF modulated sigma54 specific transcriptional regulator Fis family
CE463_08945	ENOG4105BZU	Histidine kinase
CE463_08950	ENOG4108ZI4	Glyoxalase Bleomycin resistance protein (Dioxygenase
CE463_08955	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
CE463_08960	ENOG4105BZU	Histidine kinase
CE463_08970	ENOG4105ERG	peptidase m48, ste24p
CE463_08980	ENOG4105EZX	Catalyzes the phosphorylation of N-acetyl-D-glucosamine (GlcNAc) derived from cell-wall degradation, yielding GlcNAc-6-P (By similarity)
CE463_08985	ENOG4106N3A	copper homeostasis protein cutc
CE463_08990	ENOG4108V1T	peptidylprolyl cis-trans isomerase
CE463_08995	ENOG4105CJ1	ABC, transporter
CE463_09015	ENOG4105PTV	Nudix Hydrolase
CE463_09040	ENOG4105BZG	amino acid carrier protein
CE463_09045	ENOG4108KMH	lipoate-protein ligase a
CE463_09050	ENOG4105C2W	permease
CE463_09055	ENOG4105BZU	Histidine kinase
CE463_09060	ENOG4105RKX	Protein of unknown function (DUF2498)
CE463_09065	ENOG4105UQX	Mate efflux family protein
CE463_09070	ENOG41075H3	AraC family transcriptional regulator
CE463_09075	ENOG4107R1I	NAD-dependent malic enzyme
CE463_09080	ENOG4105UYK	outer membrane protein a
CE463_09085	ENOG4105UYK	outer membrane protein a
CE463_09090	ENOG4105UYK	outer membrane protein a
CE463_09110	ENOG4105C8J	)-transporter
CE463_09115	ENOG4105D78	K07001 NTE family protein
CE463_09120	ENOG4105BZU	Histidine kinase
CE463_09125	ENOG4105ENT	Efflux transporter rnd family, mfp subunit
CE463_09140	ENOG4105CCT	upf0313 protein
CE463_09155	ENOG410600T	transposase
CE463_09170	ENOG4105NHU	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group (By similarity)
CE463_09175	ENOG4105D8C	Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity)
CE463_09180	ENOG4105E4C	Lytic transglycosylase catalytic
CE463_09190	ENOG4108VC8	Peptidase family M23
CE463_09205	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
CE463_09215	ENOG4105CIY	formyltetrahydrofolate deformylase
CE463_09220	ENOG4105C66	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity)
CE463_09230	ENOG4107QR8	Thioredoxin
CE463_09235	ENOG4107YAK	holo-(acyl carrier protein) synthase 2
CE463_09240	ENOG4107TT5	NLP P60 protein
CE463_09245	ENOG4105EBA	Specifically methylates the adenine in position 1618 of 23S rRNA (By similarity)
CE463_09260	ENOG4107N1Q	ErfK YbiS YcfS YnhG family protein
CE463_09310	ENOG4107QPN	acyl-Coa dehydrogenase
CE463_09315	ENOG4105BZS	acriflavin resistance protein
CE463_09325	ENOG4105CA9	Pyruvate kinase
CE463_09330	ENOG4106KNT	transcriptional regulator
CE463_09355	ENOG4105CBM	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 (By similarity)
CE463_09360	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
CE463_09375	ENOG4105VYW	UPF0251 protein
CE463_09405	ENOG4105D24	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
CE463_09410	ENOG4105DD5	Flagellar motor switch protein
CE463_09415	ENOG4105VTB	flagellar biosynthesis protein fliO
CE463_09420	ENOG4105CN7	Flagellar biosynthetic protein FliP
CE463_09425	ENOG4105VS8	Flagellar biosynthetic protein fliq
CE463_09430	ENOG4105D19	Role in flagellar biosynthesis (By similarity)
CE463_09435	ENOG4105D00	flagellar biosynthetic protein flhB
CE463_09440	ENOG4105D7B	Flagellar biosynthesis protein flha
CE463_09445	ENOG4105FZW	flagellar biosynthesis regulator FlhF
CE463_09450	ENOG4107R21	site-determining protein
CE463_09455	ENOG4105DN4	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
CE463_09460	ENOG4108VYJ	response regulator receiver protein
CE463_09465	ENOG4108KCC	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P) (By similarity)
CE463_09475	ENOG4105D3R	alkyl hydroperoxide reductase
CE463_09495	ENOG4105PFA	Catalyzes the conversion of 5-hydroxyuridine (ho5U) to 5-methoxyuridine (mo5U) at position 34 in tRNA (By similarity)
CE463_09500	ENOG4105DA6	Catalyzes the conversion of 5-methoxyuridine (mo5U) to uridine-5-oxyacetic acid (cmo5U) at position 34 in tRNA. May also participate in the methylation of uridine-5-oxyacetic acid (cmo5U) to uridine-5-oxyacetic acid methyl ester (mcmo5U) (By similarity)
CE463_09520	ENOG4105C9M	aspartyl-trna synthetase
CE463_09525	ENOG4105CDY	transcriptional regulatory protein
CE463_09530	ENOG4105DIJ	Phosphoethanolamine transferase
CE463_09585	ENOG4105E2R	ROK family
CE463_09590	ENOG4105CE4	GlcNAc 6-P deacetylase
CE463_09595	ENOG4105CKA	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion (By similarity)
CE463_09610	ENOG4105E2D	ec 3.2.1.52
CE463_09615	ENOG4105CX6	glutaminyL-tRNA synthetase
CE463_09620	ENOG41090R7	Ferric uptake
CE463_09630	ENOG4105MHQ	Low-potential electron donor to a number of redox enzymes (By similarity)
CE463_09635	ENOG4105NNH	LexA regulated protein
CE463_09645	ENOG4105EV9	Alpha Beta Hydrolase
CE463_09650	ENOG4107CDU	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated (By similarity)
CE463_09655	ENOG4107QIX	Phosphoglucomutase (EC 5.4.2.2
CE463_09670	ENOG4105CVE	Lytic murein transglycosylase
CE463_09675	ENOG4108T9J	Cdp-alcohol phosphatidyltransferase
CE463_09680	ENOG4108VGW	abc transporter atp-binding protein
CE463_09685	ENOG4105CXZ	ABC transporter, permease
CE463_09690	ENOG4105VNH	ABC transporter solute-binding protein
CE463_09700	ENOG4107ZN8	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity (By similarity)
CE463_09710	ENOG4107R50	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
CE463_09715	ENOG4105KQ5	peptidylprolyl cis-trans isomerase
CE463_09730	ENOG4105CFU	surface antigen
CE463_09735	ENOG4105MA0	exported protein
CE463_09750	ENOG4108WPH	sigma 54 modulation protein ribosomal protein S30EA
CE463_09755	ENOG4105BZU	Histidine kinase
CE463_09760	ENOG4107SC1	transglycosylase
CE463_09765	ENOG41060NJ	transcriptional regulator
CE463_09775	ENOG4105NAU	thioesterase Superfamily protein
CE463_09790	ENOG4105E9H	Lytic Murein transglycosylase
CE463_09795	ENOG4108RW0	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
CE463_09800	ENOG4105D1A	Methyltransferase
CE463_09805	ENOG4108UMW	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
CE463_09810	ENOG4107RZZ	dna polymerase iii epsilon subunit
CE463_09820	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
CE463_09825	ENOG4107QPN	acyl-Coa dehydrogenase
CE463_09830	ENOG4105F55	Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate (By similarity)
CE463_09835	ENOG4105E7A	Glutamine amidotransferase
CE463_09845	ENOG4105CHW	UPF0052 protein
CE463_09855	ENOG4105BZU	Histidine kinase
CE463_09865	ENOG4105WH1	Two component transcriptional regulator luxr family
CE463_09870	ENOG4105BZU	Histidine kinase
CE463_09875	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
CE463_09890	ENOG4107QIW	Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity)
CE463_09895	ENOG4108BGM	Quinol dehydrogenase periplasmic component
CE463_09900	ENOG4105GXZ	Ferredoxin-type protein NapH
CE463_09910	ENOG4105CUW	cytochrome C-TYPE protein
CE463_09915	ENOG4108RIR	Molybdenum cofactor biosynthesis protein
CE463_09920	ENOG4108YXW	Together with MoaA, is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
CE463_09925	ENOG4105M00	molybdopterin converting factor, subunit 1
CE463_09930	ENOG4108ZAF	Molybdopterin
CE463_09935	ENOG4108S6J	ABC transporter, periplasmic molybdate-binding protein
CE463_09940	ENOG4105E0C	molybdate abc transporter
CE463_09945	ENOG4105CGB	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system (By similarity)
CE463_09950	ENOG4105D3C	The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters (By similarity)
CE463_09965	ENOG4105QYK	bacteriophage lambda Bor protein homolog
CE463_09970	ENOG4105QYK	bacteriophage lambda Bor protein homolog
CE463_09975	ENOG4105D06	uba thif-type nad fad binding protein
CE463_09980	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
CE463_09985	ENOG4105EUJ	GTP cyclohydrolase i
CE463_09990	ENOG4105C8Q	Methyl-accepting chemotaxis
CE463_09995	ENOG4105CKU	formyltetrahydrofolate synthetase
CE463_10005	ENOG4105CC0	LysR family Transcriptional regulator
CE463_10010	ENOG4108YYC	ycei family
CE463_10035	ENOG4105D42	Cleaves the N-terminal amino acid of tripeptides (By similarity)
CE463_10045	ENOG4105DP5	Catalyzes the biosynthesis of agmatine from arginine (By similarity)
CE463_10060	ENOG4105I9P	Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor (By similarity)
CE463_10070	ENOG4105D82	Glutamate dehydrogenase
CE463_10075	ENOG4105FE9	pseudouridine synthase
CE463_10080	ENOG4105DJ2	Major Facilitator Superfamily
CE463_10100	ENOG4106428	Protein of unknown function (DUF2496)
CE463_10110	ENOG4108Q2J	Inner membrane protein YebE
CE463_10115	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
CE463_10120	ENOG4105C4M	(Ubiquinol oxidase) subunit I
CE463_10145	ENOG4105F27	Major Facilitator
CE463_10150	ENOG4105CV8	reductase
CE463_10155	ENOG41067V3	Antibiotic biosynthesis monooxygenase
CE463_10180	ENOG4105HEI	LysR family (Transcriptional regulator
CE463_10185	ENOG4108JQ0	Key enzyme in the regulation of glycerol uptake and metabolism (By similarity)
CE463_10190	ENOG4105D8C	Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity)
CE463_10195	ENOG4105CXY	transporter
CE463_10200	ENOG4105E98	transcriptional regulator DeoR family
CE463_10210	ENOG4105C6V	Glycerol-3-phosphate dehydrogenase
CE463_10215	ENOG4106MZZ	glycerophosphoryl diester phosphodiesterase
CE463_10220	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
CE463_10230	ENOG4105CVI	Transcriptional regulator
CE463_10235	ENOG4108WFC	UPF0438 protein yifE
CE463_10240	ENOG4108QSZ	General inhibitor of pancreatic serine proteases inhibits chymotrypsin, trypsin, elastases, factor X, kallikrein as well as a variety of other proteases (By similarity)
CE463_10260	ENOG4105CUG	Oligopeptidase b
CE463_10280	ENOG4105E68	Sulfatase
CE463_10285	ENOG4105PAN	UPF0352 protein
CE463_10290	ENOG4106V8H	Nucleoid-associated protein
CE463_10295	ENOG4107FKK	extracellular solute-binding protein family 1
CE463_10300	ENOG4105D56	permease protein
CE463_10305	ENOG4105EG2	ABC transporter, permease
CE463_10310	ENOG4108IJ9	(ABC) transporter
CE463_10315	ENOG4105CSR	polyphosphate kinase 2
CE463_10325	ENOG4105C02	permease
CE463_10330	ENOG41082K8	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Interacts with IscS and stimulates its activity. Then, accepts a sulfur from IscS and transfers it in turn to TusD (By similarity)
CE463_10335	ENOG4105ERG	peptidase m48, ste24p
CE463_10345	ENOG4105K89	arsenate reductase
CE463_10360	ENOG4105DWU	Membrane
CE463_10365	ENOG4108JEH	abc transporter atp-binding protein
CE463_10370	ENOG4106PMH	Extracellular solute-binding protein family 3
CE463_10375	ENOG4105DSP	amino acid AbC transporter
CE463_10395	ENOG4105F1A	Pyruvate formate-lyase
CE463_10400	ENOG4105BZU	Histidine kinase
CE463_10405	ENOG4107QMW	pyridine nucleotide-disulfide oxidoreductase
CE463_10410	ENOG4105DN3	alpha-2-macroglobulin domain protein
CE463_10415	ENOG4108JQB	penicillin-binding protein 1C
CE463_10425	ENOG4105D8I	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS (By similarity)
CE463_10435	ENOG4105EN6	Membrane
CE463_10440	ENOG4105I03	Flagellin
CE463_10460	ENOG4105MQ3	flagellar protein FliS
CE463_10470	ENOG4105JKQ	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Binds vitamin B12 and delivers it to the periplasmic surface of BtuC (By similarity)
CE463_10480	ENOG4105DUF	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively (By similarity)
CE463_10495	ENOG4108NVR	Methyl-accepting chemotaxis
CE463_10510	ENOG4105CYM	Glutathione S-transferase
CE463_10520	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
CE463_10525	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
CE463_10530	ENOG4105C3U	ABC transporter
CE463_10535	ENOG4105E5M	Multidrug resistance protein D
CE463_10540	ENOG4105EJC	lysr family transcriptional regulator
CE463_10545	ENOG4107H9G	Necessary for formate dehydrogenase activity (By similarity)
CE463_10550	ENOG4107QKC	Oxidoreductase alpha (molybdopterin) subunit
CE463_10560	ENOG4107YUN	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division (By similarity)
CE463_10570	ENOG4105D0A	hydroxylase
CE463_10575	ENOG4105EAK	ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family
CE463_10580	ENOG4105D43	The glycine cleavage system catalyzes the degradation of glycine (By similarity)
CE463_10585	ENOG4105KE9	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity)
CE463_10590	ENOG4105CBI	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
CE463_10610	ENOG4105D3R	alkyl hydroperoxide reductase
CE463_10615	ENOG4105W87	Cbs domain
CE463_10620	ENOG4105E2N	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) (By similarity)
CE463_10625	ENOG4105C6U	Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity)
CE463_10630	ENOG4105VIE	preprotein translocase, subunit YajC
CE463_10635	ENOG4107QN8	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
CE463_10640	ENOG4107RAB	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
CE463_10645	ENOG4105KHC	sulfurtransferase
CE463_10655	ENOG4106RZ4	Peptidase U32
CE463_10660	ENOG4105CFP	Peptidase U32
CE463_10665	ENOG4105XPQ	lipid carrier protein
CE463_10675	ENOG4105CVS	RNA methyltransferase TrmH family, group 1
CE463_10680	ENOG4108ZF1	Transcriptional regulator, BadM Rrf2 family
CE463_10685	ENOG4105C3J	Cysteine desulfurase
CE463_10690	ENOG4107XTC	May be involved in the formation or repair of Fe-S clusters present in iron-sulfur proteins
CE463_10695	ENOG4108Z4V	iron-sulfur cluster assembly
CE463_10700	ENOG4108SWN	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA (By similarity)
CE463_10705	ENOG4105C9I	Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB
CE463_10710	ENOG4108ZIT	Ferredoxin, 2FE-2S
CE463_10720	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
CE463_10725	ENOG4108UGX	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity)
CE463_10730	ENOG4105C55	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
CE463_10740	ENOG4105HSZ	Cytoskeletal protein that is involved in cell-shape control through regulation of the length of the long axis (By similarity)
CE463_10745	ENOG4105C4E	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (By similarity)
CE463_10750	ENOG4105CUT	histidyl-tRNA synthetase
CE463_10755	ENOG4105N21	Membrane
CE463_10760	ENOG4105CNE	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
CE463_10765	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
CE463_10770	ENOG4105VPD	cellular component movement
CE463_10775	ENOG4105CHQ	Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella (By similarity)
CE463_10780	ENOG4107QIK	phosphoribosylformylglycinamidine synthase
CE463_10790	ENOG4105CKW	Inner membrane protein yedI
CE463_10795	ENOG4105DPN	Oligoendopeptidase f
CE463_10805	ENOG410600T	transposase
CE463_10830	ENOG4105N5T	Radical SAM Protein
CE463_10840	ENOG4105C42	Type I secretion membrane fusion protein (HlyD
CE463_10900	ENOG4105RKW	reductase (By
CE463_10905	ENOG4105CSX	c4-dicarboxylate anaerobic carrier
CE463_10910	ENOG4105CHM	Aminotransferase
CE463_10920	ENOG41090BQ	Glutaredoxin
CE463_10925	ENOG4106HRJ	d-alanyl-d-alanine carboxypeptidase
CE463_10930	ENOG4105CFI	type iii restriction protein res subunit
CE463_10935	ENOG4105EFX	secretion protein, HlyD family
CE463_10940	ENOG4105KK7	inner membrane protein YiaW
CE463_10950	ENOG4108NEV	two component transcriptional regulator, LytTR family
CE463_10955	ENOG4108HRK	Histidine kinase
CE463_10975	ENOG4108EKI	Dehydrogenase
CE463_10985	ENOG4105EZI	multiple antibiotic resistance (MarC)-related protein
CE463_10990	ENOG4107QSI	ABC, transporter
CE463_10995	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
CE463_11000	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
CE463_11005	ENOG4105C3U	ABC transporter
CE463_11015	ENOG4108JQ7	(ABC) transporter
CE463_11020	ENOG4105DU1	integral membrane protein, terc
CE463_11025	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
CE463_11035	ENOG4105CK2	sodium dicarboxylate symporter
CE463_11050	ENOG4105CD3	dihydroorotase
CE463_11060	ENOG4108NVR	Methyl-accepting chemotaxis
CE463_11065	ENOG4105K59	histidine triad (HIT) protein
CE463_11100	ENOG4107QN8	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
CE463_11105	ENOG4107RAB	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
CE463_11110	ENOG4107SDU	Methyl-accepting chemotaxis
CE463_11120	ENOG410600T	transposase
CE463_11135	ENOG4105CNR	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
CE463_11140	ENOG4105C8S	subunit m
CE463_11145	ENOG4105D65	subunit l
CE463_11150	ENOG41080EA	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
CE463_11155	ENOG4107UFS	subunit j
CE463_11160	ENOG4105P3U	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
CE463_11165	ENOG4105CMZ	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone (By similarity)
CE463_11170	ENOG4108IEH	NADH dehydrogenase subunit g
CE463_11175	ENOG4107QIZ	NADH dehydrogenase
CE463_11180	ENOG4105GKE	subunit e
CE463_11185	ENOG4105CQV	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
CE463_11190	ENOG4105ES3	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
CE463_11195	ENOG4105KWU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
CE463_11200	ENOG4105ER2	Ompa motb domain protein
CE463_11220	ENOG4105HA9	of methanol dehydrogenase type
CE463_11230	ENOG4105HPZ	Involved in the removal of murein from the sacculus. May also facilitate integration of nascent murein strands into the sacculus by cleaving the peptide bonds between neighboring strands in mature murein (By similarity)
CE463_11235	ENOG4105EZ7	amino acid ABC transporter
CE463_11240	ENOG4106TNF	Periplasmic binding protein
CE463_11245	ENOG4105EAD	ABC transporter
CE463_11250	ENOG4105CDA	abc transporter atp-binding protein
CE463_11260	ENOG4105VFU	Rna-binding protein
CE463_11265	ENOG4107RGM	aldo keto reductase
CE463_11275	ENOG4108RU0	short-chain dehydrogenase reductase
CE463_11295	ENOG4105CBN	LysR family transcriptional regulator
CE463_11310	ENOG4105BZU	Histidine kinase
CE463_11315	ENOG4108DBC	nitroreductase
CE463_11330	ENOG4108SC4	)-transporter
CE463_11335	ENOG4105DUM	transcriptional regulator, lysR family
CE463_11340	ENOG4107R11	Transcriptional regulator
CE463_11345	ENOG4108JEN	Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate (By similarity)
CE463_11350	ENOG4105CAT	Cytidine monophosphate kinase
CE463_11355	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
CE463_11360	ENOG41080YA	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
CE463_11370	ENOG4105CFV	Tetratricopeptide repeat protein
CE463_11375	ENOG4106EG9	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) (By similarity)
CE463_11390	ENOG4105FD2	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) (By similarity)
CE463_11395	ENOG4105EIZ	Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity)
CE463_11400	ENOG4105VRT	cytoplasmic protein
CE463_11405	ENOG4108WBT	adenosyltransferase
CE463_11425	ENOG4107S6Z	Na H antiporter
CE463_11430	ENOG4107104	thymidine kinase
CE463_11440	ENOG4108RMJ	sensory transduction regulator
CE463_11455	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
CE463_11470	ENOG410600T	transposase
CE463_11480	ENOG4105QA4	4Fe-4S Ferredoxin, iron-sulfur binding domain protein
CE463_11485	ENOG4105CJ5	hydrogenase 2 b cytochrome subunit
CE463_11490	ENOG4105DPX	Hydrogenase, large subunit
CE463_11495	ENOG4108USZ	hydrogenase
CE463_11500	ENOG4108WGS	hydrogenase 2-specific chaperone
CE463_11510	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
CE463_11515	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
CE463_11525	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
CE463_11530	ENOG4107RSS	Hydrogenase accessory protein HypB
CE463_11535	ENOG4105WMM	Probably plays a role in a hydrogenase nickel cofactor insertion step (By similarity)
CE463_11540	ENOG4105C45	hydrogenase expression formation protein (HypE)
CE463_11545	ENOG4105CQS	hydrogenase expression formation protein HypD
CE463_11550	ENOG4105WRB	Hydrogenase assembly chaperone hypC hupF
CE463_11560	ENOG4105EM7	Selenocysteine-specific translation elongation factor
CE463_11565	ENOG4105C1Y	Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis (By similarity)
CE463_11575	ENOG4105I6X	formate hydrogenlyase maturation
CE463_11580	ENOG4105C47	NADH ubiquinone oxidoreductase 20 kda subunit
CE463_11590	ENOG4105CQV	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
CE463_11595	ENOG4107TDF	Formate hydrogenlyase subunit 4
CE463_11600	ENOG4108JPZ	Monovalent cation H antiporter subunit D
CE463_11605	ENOG4108MFN	small subunit of hydrogenase-3, iron-sulfur protein (part of formate hydrogenlyase (FHL) complex)
CE463_11650	ENOG4107H9G	Necessary for formate dehydrogenase activity (By similarity)
CE463_11655	ENOG4105F3K	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity)
CE463_11660	ENOG4105CJX	Molecular chaperone. Has ATPase activity (By similarity)
CE463_11670	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
CE463_11675	ENOG4105CFX	Catalyzes the ferrous insertion into protoporphyrin IX (By similarity)
CE463_11680	ENOG4105WJG	Glutathione
CE463_11685	ENOG4107RE1	Inosine-guanosine kinase
CE463_11690	ENOG4105C8Q	Methyl-accepting chemotaxis
CE463_11735	ENOG4105F3T	(LipO)protein
CE463_11745	ENOG4108IQC	2,3-dihydroxybenzoate-AMP ligase
CE463_11750	ENOG4105WQI	isochorismatase
CE463_11755	ENOG4105CEY	Amp-dependent synthetase and ligase
CE463_11760	ENOG4105X17	23-dihydro-2,3-dihydroxybenzoate dehydrogenase
CE463_11775	ENOG4108MES	Periplasmic binding protein
CE463_11780	ENOG4108TSE	Transferase
CE463_11785	ENOG4105E0A	ABC, transporter
CE463_11790	ENOG4105TVJ	transport system, permease
CE463_11795	ENOG4105DQ5	transport system permease protein
CE463_11800	ENOG4105D05	Receptor
CE463_11815	ENOG4105QZU	Inner membrane protein YfeZ
CE463_11820	ENOG4107QUT	magnesium and cobalt transport protein CorA
CE463_11825	ENOG4105DWH	electron transfer flavoprotein-ubiquinone oxidoreductase
CE463_11830	ENOG4105BZJ	Electron transfer flavoprotein
CE463_11835	ENOG4105C10	Electron transfer flavoprotein
CE463_11840	ENOG4107QM1	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine (By similarity)
CE463_11845	ENOG4105CMY	5-enolpyruvylshikimate-3-phosphate synthase
CE463_11850	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
CE463_11855	ENOG4108NVR	Methyl-accepting chemotaxis
CE463_11860	ENOG4105D4P	Coproporphyrinogen iii oxidase
CE463_11865	ENOG4105DVS	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
CE463_11885	ENOG410600T	transposase
CE463_11890	ENOG4105SG9	biopolymer transport protein, ExbD
CE463_11910	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
CE463_11915	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
CE463_11965	ENOG4105FQ6	thiopurine methyltransferase
CE463_11975	ENOG4108BY2	phosphohistidine phosphatase
CE463_11985	ENOG4108IPJ	Membrane
CE463_11990	ENOG4108J59	Extracellular solute-binding protein, family 5
CE463_11995	ENOG4105CZI	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
CE463_12000	ENOG4108JA2	transcriptioN-repair coupling factor
CE463_12010	ENOG4105D60	lipoprotein releasing system transmembrane protein
CE463_12015	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
CE463_12020	ENOG4105D60	lipoprotein releasing system transmembrane protein
CE463_12040	ENOG4105DEA	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation
CE463_12045	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
CE463_12050	ENOG4105CHN	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
CE463_12055	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
CE463_12060	ENOG4105K70	DNA-binding protein
CE463_12065	ENOG4105EIN	peptidylprolyl cis-trans isomerase
CE463_12070	ENOG4105C5H	ABC transporter
CE463_12075	ENOG4107QN1	sodium solute
CE463_12080	ENOG41062QD	Membrane
CE463_12095	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
CE463_12100	ENOG4105BZG	amino acid carrier protein
CE463_12105	ENOG410849A	acetyltransferase, (GNAT) family
CE463_12115	ENOG4106HK8	GPR1 FUN34 yaaH family protein
CE463_12145	ENOG4105E39	Enoyl-CoA hydratase
CE463_12150	ENOG4107QX3	carboxylase
CE463_12170	ENOG4105C26	Dehydrogenase
CE463_12175	ENOG4105C1G	acyl-Coa dehydrogenase
CE463_12180	ENOG4105E39	Enoyl-CoA hydratase
CE463_12185	ENOG4105E39	Enoyl-CoA hydratase
CE463_12190	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
CE463_12195	ENOG4105CHR	reductase
CE463_12200	ENOG4105D5Q	Arginine ornithine antiporter
CE463_12205	ENOG4105HF0	Membrane
CE463_12240	ENOG4105D29	Helix-turn-helix type 11 domain protein
CE463_12250	ENOG4105K8F	Phosphoribosyl-amp cyclohydrolase
CE463_12255	ENOG4105C0S	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity)
CE463_12260	ENOG4105BZU	Histidine kinase
CE463_12270	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
CE463_12275	ENOG4105CJV	Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase
CE463_12280	ENOG4108UJE	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity)
CE463_12285	ENOG4105ECC	imidazole-glycerol-phosphate dehydratase
CE463_12290	ENOG4105CIH	Imidazole acetol-phosphate transaminase
CE463_12295	ENOG4105CEK	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity)
CE463_12300	ENOG4105E21	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity)
CE463_12310	ENOG4105DVT	helicase
CE463_12315	ENOG41072GX	Peptidase M22 Glycoprotease
CE463_12325	ENOG4108MXF	Alpha Beta Hydrolase
CE463_12330	ENOG4105CEY	Amp-dependent synthetase and ligase
CE463_12350	ENOG4105FBT	Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs (By similarity)
CE463_12355	ENOG4105WD1	Membrane
CE463_12360	ENOG4109003	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity)
CE463_12365	ENOG4107QMP	dna polymerase iii subunits gamma and tau
CE463_12370	ENOG4105KDX	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection (By similarity)
CE463_12375	ENOG4105DWD	nucleoside recognition domain protein
CE463_12380	ENOG4105WH1	Two component transcriptional regulator luxr family
CE463_12390	ENOG4105CQ7	ATP-dependent helicase
CE463_12400	ENOG4105KW6	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance (By similarity)
CE463_12405	ENOG4105C5X	domain protein
CE463_12410	ENOG4105CR7	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA (By similarity)
CE463_12415	ENOG4105D4F	Synthesizes selenophosphate from selenide and ATP (By similarity)
CE463_12425	ENOG4105FAT	Acyl-transferase
CE463_12430	ENOG4105DR4	Methyltransferase
CE463_12440	ENOG4105VSY	K01512 acylphosphatase EC 3.6.1.7
CE463_12445	ENOG4108TGY	Glutathione S-transferase
CE463_12450	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
CE463_12455	ENOG4105D1F	ATP-binding protein
CE463_12460	ENOG4105DBI	uridine monophosphokinase
CE463_12465	ENOG4105DHP	deoxycytidine triphosphate deaminase
CE463_12470	ENOG4105CJ3	phosphate transporter
CE463_12475	ENOG4105C03	ribonuclease
CE463_12480	ENOG4105EI2	Pseudouridine synthase
CE463_12485	ENOG4108YZS	Had-superfamily hydrolase, subfamily ia, variant 1
CE463_12490	ENOG4108UHJ	MAF-like protein
CE463_12495	ENOG4105FCQ	metal-binding, possibly nucleic acid-binding protein
CE463_12500	ENOG4105VGS	50s ribosomal protein l32
CE463_12505	ENOG4105C6B	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA (By similarity)
CE463_12510	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
CE463_12515	ENOG4105CJF	Malonyl coA-acyl carrier protein transacylase
CE463_12520	ENOG4105CHR	reductase
CE463_12525	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
CE463_12530	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
CE463_12535	ENOG4105YAZ	4-amino-4-deoxychorismate lyase
CE463_12540	ENOG4105HHA	aminodeoxychorismate lyase
CE463_12545	ENOG4108ZMD	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity)
CE463_12550	ENOG4107QRG	dna polymerase iii
CE463_12555	ENOG4105F8V	Hydrolase, tatD family
CE463_12570	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
CE463_12580	ENOG4105F1S	paraquat-inducible protein a
CE463_12590	ENOG4105CR4	methylisocitrate lyase
CE463_12595	ENOG4105BZN	citrate synthase
CE463_12600	ENOG4105DXD	2-methylcitrate dehydratase
CE463_12640	ENOG4105PDP	Short chain dehydrogenase
CE463_12670	ENOG41067QW	Transcriptional regulator
CE463_12735	ENOG410600T	transposase
CE463_12745	ENOG4105DAN	ATP-dependent protease
CE463_12750	ENOG4108RKI	Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl- ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)- decenoyl-ACP. Can catalyze the dehydratase reaction for beta- hydroxyacyl-ACPs with saturated chain lengths up to 16 0, being most active on intermediate chain length (By similarity)
CE463_12755	ENOG4105WFT	During stationary phase, converts 70S ribosomes to an inactive dimeric form (100S ribosomes) (By similarity)
CE463_12765	ENOG4105C5H	ABC transporter
CE463_12775	ENOG4105C4H	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA (By similarity)
CE463_12785	ENOG4108T7E	Contributes to the efficiency of the cell division process by stabilizing the polymeric form of the cell division protein FtsZ. Acts by promoting interactions between FtsZ protofilaments and suppressing the GTPase activity of FtsZ (By similarity)
CE463_12790	ENOG4107QYT	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor (By similarity)
CE463_12800	ENOG410600T	transposase
CE463_12815	ENOG4105CD8	aminopeptidase N
CE463_12820	ENOG4105CN1	protease
CE463_12825	ENOG41073DY	may be a structural element that influences the osmotic activation of ProP at a post-translational level (By similarity)
CE463_12830	ENOG4108ZGC	gaf domain protein
CE463_12840	ENOG4105EUH	cytochrome C oxidase, cbb3-type, subunit i
CE463_12855	ENOG4105D6P	C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex (By similarity)
CE463_12865	ENOG4105C59	p-type ATPase
CE463_12880	ENOG4105DS0	Transcriptional regulator, Crp Fnr family
CE463_12885	ENOG4105Q9Y	Universal stress protein
CE463_12890	ENOG4105CB3	Required for the thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32) (By similarity)
CE463_12910	ENOG4105MRB	Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose (By similarity)
CE463_12920	ENOG4105CNN	ABC, transporter
CE463_12925	ENOG4105E9V	Periplasmic binding protein LacI transcriptional regulator
CE463_12930	ENOG4108RVA	ribokinase
CE463_12935	ENOG4105ETE	Transcriptional regulator (LacI family
CE463_12955	ENOG4105NDF	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity)
CE463_12970	ENOG4105BZU	Histidine kinase
CE463_12975	ENOG4108ZUF	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
CE463_12980	ENOG4105C6A	phenylalanyl-tRNA synthetase (beta subunit)
CE463_12985	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
CE463_12990	ENOG4108YZX	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity)
CE463_13000	ENOG4108UUX	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity)
CE463_13005	ENOG4105C22	threonyL-tRNA synthetase
CE463_13020	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
CE463_13025	ENOG4108HWB	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
CE463_13030	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
CE463_13035	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
CE463_13040	ENOG4105E05	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
CE463_13045	ENOG4105XPH	Ferredoxin
CE463_13050	ENOG4105CA3	membrane-bound lytic murein transglycosylase
CE463_13055	ENOG4105XZD	Fe-S protein
CE463_13060	ENOG4105DM4	PTS System
CE463_13065	ENOG4105DE4	1-phosphofructokinase
CE463_13070	ENOG4105DTZ	bifunctional PTS system fructose-specific transporter subunit IIA HPr protein
CE463_13075	ENOG4107B7Y	DNA-binding transcriptional regulator FruR
CE463_13080	ENOG4105E0U	tyrosine-specific transport protein
CE463_13095	ENOG4105C1J	atp-dependent rna helicase
CE463_13105	ENOG4105D10	5-enolpyruvylshikimate-3-phosphate phospholyase
CE463_13110	ENOG4105C76	Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue (By similarity)
CE463_13115	ENOG4108DG9	Smr protein MutS2
CE463_13120	ENOG4105BZU	Histidine kinase
CE463_13170	ENOG4108Z8G	Alkylphosphonate utilization operon protein PhnA
CE463_13175	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
CE463_13180	ENOG4105CHU	acetyl-coa acetyltransferase
CE463_13185	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
CE463_13225	ENOG4105CKF	membrane protein involved in aromatic hydrocarbon degradation
CE463_13230	ENOG4105CKF	membrane protein involved in aromatic hydrocarbon degradation
CE463_13235	ENOG4105D58	Diguanylate phosphodiesterase
CE463_13240	ENOG4105CHU	acetyl-coa acetyltransferase
CE463_13250	ENOG4105CK2	sodium dicarboxylate symporter
CE463_13255	ENOG4105NBK	UPF0345 protein
CE463_13260	ENOG4105EJQ	L-serine dehydratase
CE463_13270	ENOG4105EJQ	L-serine dehydratase
CE463_13275	ENOG4105CVE	Lytic murein transglycosylase
CE463_13280	ENOG4105VNG	YcgL domain-containing protein
CE463_13285	ENOG4105K7U	Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization (By similarity)
CE463_13290	ENOG4107QMS	site-determining protein
CE463_13295	ENOG4105VJP	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell (By similarity)
CE463_13305	ENOG4108VKV	Monofunctional biosynthetic peptidoglycan transglycosylase
CE463_13310	ENOG4105XW2	UPF0263 protein
CE463_13350	ENOG4108V3G	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity)
CE463_13355	ENOG4108SXK	Transporter Drug Metabolite Exporter family
CE463_13360	ENOG4108HH9	Catalyzes two reactions the first one is the production of beta-formyl glycinamide ribonucleotide (GAR) from formate, ATP and beta GAR
CE463_13365	ENOG4107UW8	HAD-superfamily hydrolase subfamily IA variant 3
CE463_13375	ENOG4108R6K	riboflavin synthase, subunit alpha
CE463_13380	ENOG4105W1I	UPF0253 protein
CE463_13385	ENOG4107QI1	Mate efflux family protein
CE463_13420	ENOG4105CQ2	DNA polymerase
CE463_13450	ENOG4105NWR	lipid A biosynthesis (Kdo)2-(Lauroyl)-lipid IVA acyltransferase
CE463_13460	ENOG4105DUM	transcriptional regulator, lysR family
CE463_13470	ENOG4105EFU	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin (By similarity)
CE463_13475	ENOG4105CBN	LysR family transcriptional regulator
CE463_13480	ENOG4105CHR	reductase
CE463_13485	ENOG4105CS2	ec 3.2.1.21
CE463_13490	ENOG4108KB2	LysR family Transcriptional regulator
CE463_13510	ENOG4105CSX	c4-dicarboxylate anaerobic carrier
CE463_13520	ENOG4107MBR	17 kDa surface antigen
CE463_13540	ENOG4105EHG	Permease protein
CE463_13560	ENOG4108VWS	Yaeq family
CE463_13605	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
CE463_13630	ENOG4105K6T	rare lipoprotein A
CE463_13635	ENOG4105DUC	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division (By similarity)
CE463_13640	ENOG4105DAH	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF (By similarity)
CE463_13650	ENOG4106371	Methyltransferase
CE463_13660	ENOG4107S90	membrAne
CE463_13670	ENOG4105CTQ	phosphohexokinase
CE463_13705	ENOG4105PAD	Hydrolase
CE463_13760	ENOG4105CPB	ATP-dependent endonuclease of the OLD family
CE463_13775	ENOG4105VP0	transcriptional regulator, lysR family
CE463_13780	ENOG4105EJ9	Membrane
CE463_13785	ENOG4106IUH	DTW domain containing protein
CE463_13795	ENOG4105CPF	Cell wall formation (By similarity)
CE463_13805	ENOG4108V06	Glutathione peroxidase
CE463_13810	ENOG4105C1J	atp-dependent rna helicase
CE463_13815	ENOG4105K5X	acetyltransferase
CE463_13825	ENOG4105KK4	UPF0060 membrane protein
CE463_13860	ENOG41061CK	Antibiotic biosynthesis monooxygenase
CE463_13865	ENOG4107XGF	functions in a salvage pathway. Uses pyridoxamine (By similarity)
CE463_13885	ENOG4105D1N	poly(r)-hydroxyalkanoic acid synthase, class
CE463_13895	ENOG4105WQ3	Rna-binding protein
CE463_13905	ENOG4105BZ1	(ABC) transporter
CE463_13915	ENOG4105BZU	Histidine kinase
CE463_13920	ENOG4105K63	Thioredoxin
CE463_13925	ENOG4105C8P	)-transporter
CE463_13930	ENOG4107QQN	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties (By similarity)
CE463_13975	ENOG410600T	transposase
CE463_14000	ENOG4105CRQ	synthase (Component I)
CE463_14010	ENOG4105C44	Serine transporter
CE463_14015	ENOG4107QV7	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system) (By similarity)
CE463_14020	ENOG4105C9U	ATP-dependent DNA helicase RecQ
CE463_14025	ENOG4105CYN	Serine protein kinase
CE463_14035	ENOG4105ED1	spovr family
CE463_14040	ENOG4105C05	Multifunctional regulator of fatty acid metabolism (By similarity)
CE463_14045	ENOG4105DKR	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity)
CE463_14050	ENOG410635M	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein (By similarity)
CE463_14055	ENOG4105DQR	SNARE associated Golgi
CE463_14065	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
CE463_14080	ENOG4105D0C	transport protein
CE463_14085	ENOG4105CHQ	Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella (By similarity)
CE463_14090	ENOG410600T	transposase
CE463_14120	ENOG4108MRH	transcriptional regulatory protein
CE463_14125	ENOG4105CEQ	signal transduction histidine kinase regulating citrate malate metabolism
CE463_14130	ENOG4105E2R	ROK family
CE463_14135	ENOG4105C8Q	Methyl-accepting chemotaxis
CE463_14140	ENOG4105K5B	UPF0225 protein
CE463_14145	ENOG4107R5Y	anaerobic glycerol-3-phosphate dehydrogenase, subunit A
CE463_14150	ENOG4108KJ0	anaerobic glycerol-3-phosphate dehydrogenase, subunit B
CE463_14155	ENOG4105CHG	glycolate oxidase (iron-sulfur subunit)
CE463_14165	ENOG4105JJ8	Cytochrome c nitrite reductase, pentaheme subunit
CE463_14170	ENOG4105D3S	4Fe-4S Ferredoxin, iron-sulfur binding domain protein
CE463_14175	ENOG4105DVI	reductase, NrfD
CE463_14180	ENOG4105DA4	cytochrome c-type biogenesis protein
CE463_14185	ENOG4107QX9	Thiol disulfide interChange protein
CE463_14190	ENOG4108DMF	Cytochrome C biogenesis protein
CE463_14200	ENOG41061WM	D-Alanyl-D-Alanine
CE463_14205	ENOG4105C0F	tryptophanase EC 4.1.99.1
CE463_14215	ENOG4105EXX	Deoxyribodipyrimidine photolyase-related protein
CE463_14245	ENOG4105DSS	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation (By similarity)
CE463_14250	ENOG4105DZ2	Transcriptional regulator
CE463_14260	ENOG4105E0K	tonB-dependent siderophore receptor
CE463_14265	ENOG4105UEI	Transcriptional Regulator AraC Family
CE463_14275	ENOG4105CR8	Transcriptional regulator
CE463_14280	ENOG4108RYK	Nad-dependent epimerase dehydratase
CE463_14300	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
CE463_14305	ENOG4105DDY	UPF0142 protein ycaO
CE463_14310	ENOG4105TMB	Formate nitrite transporter
CE463_14315	ENOG4105C6N	Formate acetyltransferase
CE463_14325	ENOG4105CH8	Succinyl-CoA ligase ADP-forming subunit alpha
CE463_14330	ENOG4105CMV	Succinyl-CoA synthetase subunit beta
CE463_14335	ENOG4105C7S	Dehydrogenase
CE463_14340	ENOG4105C7P	2-oxoglutarate dehydrogenase, E1
CE463_14345	ENOG4105E33	succinate dehydrogenase
CE463_14350	ENOG4105C00	Succinate dehydrogenase (Flavoprotein subunit)
CE463_14355	ENOG4105N1I	succinate dehydrogenase, hydrophobic membrane anchor protein
CE463_14360	ENOG4108UTY	succinate dehydrogenase, cytochrome b556 subunit
CE463_14365	ENOG4105BZN	citrate synthase
CE463_14380	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
CE463_14385	ENOG4105CWG	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34 (By similarity)
CE463_14395	ENOG4105CEE	C4-dicarboxylate transporter
CE463_14410	ENOG4108VKG	metal-dependent hydrolase
CE463_14425	ENOG4105NRA	50s ribosomal protein l31 type b
CE463_14455	ENOG4105EG2	ABC transporter, permease
CE463_14500	ENOG4108NVR	Methyl-accepting chemotaxis
CE463_14520	ENOG4108KDD	Involved in the transport of maltose and maltodextrins (By similarity)
CE463_14530	ENOG41060NJ	transcriptional regulator
CE463_14535	ENOG4105CMR	udp-glucose 4-epimerase
CE463_14555	ENOG4105CRD	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P) (By similarity)
CE463_14565	ENOG4105CNN	ABC, transporter
CE463_14570	ENOG4105C2J	ABC transporter
CE463_14575	ENOG4105DMK	Periplasmic binding protein LacI transcriptional regulator
CE463_14580	ENOG4105EF1	ribulokinase
CE463_14590	ENOG4105CAC	Catalyzes the conversion of L-arabinose to L-ribulose (By similarity)
CE463_14595	ENOG4105ETT	transcriptional Regulator, LysR family
CE463_14600	ENOG4105CHM	Aminotransferase
CE463_14620	ENOG4105CJB	Exodeoxyribonuclease I
CE463_14630	ENOG4107R49	K07407 alpha-galactosidase EC 3.2.1.22
CE463_14645	ENOG41067MG	lrgb family
CE463_14650	ENOG4107T42	This enzyme scavenge exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis (By similarity)
CE463_14655	ENOG4108IQE	Amp-dependent synthetase and ligase
CE463_14660	ENOG4105MH2	YfcL protein
CE463_14670	ENOG4105EE5	Membrane protein terC
CE463_14675	ENOG4105UYK	outer membrane protein a
CE463_14680	ENOG4108KHX	Diguanylate cyclase
CE463_14685	ENOG4108WS1	
CE463_14695	ENOG41090A4	Pterin carbinolamine dehydratase
CE463_14700	ENOG4105MIR	Phenylalanine 4-monooxygenase
CE463_14705	ENOG4106K28	UPF0283 membrane protein
CE463_14710	ENOG4105CM6	amino acid regulated cytosolic protein
CE463_14720	ENOG4105YYT	phage shock protein B
CE463_14725	ENOG41087YS	Phage shock protein A
CE463_14730	ENOG4105E51	psp operon transcriptional activator
CE463_14735	ENOG4108J59	Extracellular solute-binding protein, family 5
CE463_14740	ENOG4108I5W	peptide transport system, permease protein
CE463_14745	ENOG4108EU3	peptide transport system, permease
CE463_14750	ENOG4108JQ3	Peptide ABC transporter ATP-binding protein
CE463_14755	ENOG4108JQ2	peptide transport system atp-binding protein
CE463_14760	ENOG4105FR9	TRNA-(Ms 2 io 6 A)-hydroxylase
CE463_14765	ENOG4105CBA	glutamine phosphoribosylpyrophosphate amidotransferase
CE463_14770	ENOG4105E96	Colicin v production protein
CE463_14775	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
CE463_14780	ENOG4105D1H	recombination factor protein RarA
CE463_14785	ENOG4107Y7W	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) (By similarity)
CE463_14790	ENOG4105CNU	cell division protein FtsK
CE463_14795	ENOG4105EW9	transcriptional regulator AsnC family
CE463_14810	ENOG4105C3M	thioredoxin reductase
CE463_14820	ENOG4107MBR	17 kDa surface antigen
CE463_14825	ENOG4108R4Z	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine (By similarity)
CE463_14830	ENOG4105DWA	May conjugate Arg from its aminoacyl-tRNA to the N- termini of proteins containing an N-terminal aspartate or glutamate
CE463_14835	ENOG4105K9U	however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity)
CE463_14840	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
CE463_14845	ENOG4105KAE	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation (By similarity)
CE463_14850	ENOG4105VEQ	Cold shock protein
CE463_14855	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
CE463_14980	ENOG4105CHH	sulfate transporter
CE463_15030	ENOG4108PCN	EamA-like transporter family
CE463_15035	ENOG4105DGN	Electron transport complex
CE463_15040	ENOG4108R3D	Electron transport complex
CE463_15050	ENOG4105D6A	Electron transport complex
CE463_15055	ENOG4108UQQ	Electron transport complex
CE463_15060	ENOG4105DZB	Electron transport complex
CE463_15065	ENOG4105CSM	endonuclease III
CE463_15070	ENOG4108UYE	Lactoylglutathione lyase
CE463_15075	ENOG4105EIY	sodium-type flagellar protein motY
CE463_15085	ENOG4105DH5	Responsible for the end-turnover of tRNA specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis (By similarity)
CE463_15090	ENOG4105D3Y	Na H antiporter
CE463_15095	ENOG4105BZU	Histidine kinase
CE463_15105	ENOG4105C1J	atp-dependent rna helicase
CE463_15110	ENOG4105KA0	thioesterase Superfamily protein
CE463_15120	ENOG4105CQB	FAD linked oxidase domain protein
CE463_15130	ENOG4105EE5	Membrane protein terC
CE463_15135	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
CE463_15145	ENOG4105D4U	had-superfamily hydrolase, subfamily iia
CE463_15150	ENOG4105CKD	glutathione-regulated potassium-efflux system protein
CE463_15160	ENOG4105CAQ	asparagine synthetase
CE463_15185	ENOG4108TGY	Glutathione S-transferase
CE463_15190	ENOG4108RXX	maleylacetoacetate isomerase
CE463_15205	ENOG4105E6K	4-Hydroxyphenylpyruvate dioxygenase
CE463_15215	ENOG4108W1A	pseudouridine synthase
CE463_15235	ENOG4107RHT	methyl-accepting chemotaxis sensory transducer with Pas Pac sensor
CE463_15245	ENOG4108MN8	Membrane
CE463_15250	ENOG4105EM2	membrane
CE463_15255	ENOG4108Z0T	Part of a sulfur-relay system (By similarity)
CE463_15260	ENOG4108S3P	Sporulation domain protein
CE463_15265	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
CE463_15270	ENOG4107QTG	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA (By similarity)
CE463_15275	ENOG4105DI7	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity)
CE463_15285	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
CE463_15290	ENOG4105CJ0	Catalyzes the oxidation of erythronate-4-phosphate to 3- hydroxy-2-oxo-4-phosphonooxybutanoate (By similarity)
CE463_15295	ENOG4105EYK	Phosphatidylglycerophosphatase B
CE463_15300	ENOG4105D01	(LipO)protein
CE463_15325	ENOG410600T	transposase
CE463_15360	ENOG4108HRN	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate (By similarity)
CE463_15365	ENOG4105CF9	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation (By similarity)
CE463_15385	ENOG4105C85	amino acid
CE463_15445	ENOG4105C2C	drug resistance transporter, Bcr CflA
CE463_15460	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
CE463_15480	ENOG4108302	MgtC SapB transporter
CE463_15530	ENOG4107QXP	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
CE463_15535	ENOG4107QZM	n-acetylglutamate synthase
CE463_15540	ENOG4105CFH	Aspartokinase
CE463_15550	ENOG4107T7U	Sulfatase
CE463_15555	ENOG4105EBE	Peptidase U61, LD-carboxypeptidase A
CE463_15565	ENOG4105K8R	UPF0145 protein
CE463_15570	ENOG4105CEP	NADH dehydrogenase
CE463_15610	ENOG4108Z4X	TRANSCRIPTIONal
CE463_15625	ENOG4105BZ8	glutamate synthase
CE463_15630	ENOG4105CBC	glutamate synthase
CE463_15635	ENOG410600T	transposase
CE463_15675	ENOG4105C1J	atp-dependent rna helicase
CE463_15680	ENOG4108MK9	spermidine N(1)-acetyltransferase
CE463_15705	ENOG4107QS8	(LipO)protein
CE463_15710	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
CE463_15715	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
CE463_15720	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
CE463_15725	ENOG4105DUK	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity)
CE463_15740	ENOG4105MK2	5-formyltetrahydrofolate cyclo-ligase
CE463_15745	ENOG4105E66	phosphoriboisomerase A
CE463_15750	ENOG4108JQ1	Dehydrogenase
CE463_15755	ENOG41080IJ	Diacylglycerol kinase
CE463_15760	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
CE463_15765	ENOG41080WI	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system (By similarity)
CE463_15770	ENOG4108ESU	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Involved in the translocation of the substrate across the membrane (By similarity)
CE463_15775	ENOG4105BZU	Histidine kinase
CE463_15785	ENOG4105CZX	twitching motility protein
CE463_15815	ENOG4108ZJT	translation initiation factor, Sui1
CE463_15850	ENOG410620I	Diguanylate cyclase
CE463_15875	ENOG4105C8N	cysteinyl-tRNA synthetase
CE463_15880	ENOG4108R5K	PPIases accelerate the folding of proteins (By similarity)
CE463_15890	ENOG4105F10	Catalyzes the hydrolysis of the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1- phosphate (lipid X) and UMP (By similarity)
CE463_15895	ENOG4105Y3U	Transglycosylase-associated protein
CE463_15905	ENOG4107EXU	Short-chain dehydrogenase reductase Sdr
CE463_15910	ENOG4105EQ2	LysR family Transcriptional regulator
CE463_15935	ENOG4105CII	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity)
CE463_15940	ENOG4105WH1	Two component transcriptional regulator luxr family
CE463_15945	ENOG4105CET	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria (By similarity)
CE463_15950	ENOG4105W49	UPF0434 protein
CE463_15955	ENOG4105CHD	Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) (By similarity)
CE463_15960	ENOG4105BZ1	(ABC) transporter
CE463_15965	ENOG4108EQH	DNA internalization-related competence protein ComEC Rec2
CE463_15980	ENOG4105D7A	ATP-binding protein
CE463_15985	ENOG4105CGF	Aromatic amino acid aminotransferase
CE463_15995	ENOG4105QMY	Porin Gram-negative type
CE463_16000	ENOG4105DVT	helicase
CE463_16015	ENOG4105C9W	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity (By similarity)
CE463_16020	ENOG4105G6Z	alkaline phosphatase
CE463_16040	ENOG4105NXH	GreA GreB family elongation factor
CE463_16045	ENOG4108KX4	response regulator
CE463_16050	ENOG4105BZU	Histidine kinase
CE463_16055	ENOG4105CXY	transporter
CE463_16060	ENOG4105BZU	Histidine kinase
CE463_16065	ENOG4106PMH	Extracellular solute-binding protein family 3
CE463_16070	ENOG4105E5Q	amino acid AbC transporter
CE463_16075	ENOG4105CDA	abc transporter atp-binding protein
CE463_16085	ENOG4105D5Q	Arginine ornithine antiporter
CE463_16100	ENOG4105C37	(CBS) domain
CE463_16110	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
CE463_16115	ENOG4105E2Z	phosphate ABC transporter (Permease
CE463_16120	ENOG4105C8U	phosphate abc transporter
CE463_16125	ENOG4108Z6B	deaminase
CE463_16135	ENOG4107QP3	malate synthase g
CE463_16140	ENOG4108I9X	Isocitrate lyase
CE463_16155	ENOG4105CZ5	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate (By similarity)
CE463_16160	ENOG4105CXB	phosphoribosylaminoimidazole synthetase
CE463_16165	ENOG4108V3E	phosphoribosylglycinamide formyltransferase
CE463_16170	ENOG4107QNR	UPF0135 protein
CE463_16175	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
CE463_16180	ENOG4105BZU	Histidine kinase
CE463_16200	ENOG4105CUU	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) (By similarity)
CE463_16205	ENOG4105C9X	ppx gppa phosphatase
CE463_16210	ENOG4105CJW	magnesium transporter
CE463_16230	ENOG4108ZW7	flagellar rod assembly protein muramidase flgj
CE463_16240	ENOG4107W7W	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity)
CE463_16245	ENOG4105CGA	flagellar basal-body rod protein FlgG
CE463_16250	ENOG4108KPB	Flagellar basal-body rod protein FlgF
CE463_16255	ENOG4105BZE	flagellar hook protein, FlgE
CE463_16265	ENOG4108ZC9	flagellar basal-body rod protein flgc
CE463_16270	ENOG4105K88	Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body (By similarity)
CE463_16275	ENOG4105BZU	Histidine kinase
CE463_16280	ENOG4107R88	Chemotaxis protein (CheV)
CE463_16300	ENOG4108RE9	Phosphodiesterase
CE463_16305	ENOG4108J59	Extracellular solute-binding protein, family 5
CE463_16315	ENOG4105I08	Pseudouridine synthase
CE463_16320	ENOG4105CPI	Metal Dependent Phosphohydrolase
CE463_16335	ENOG4108594	Permease of the drug metabolite transporter
CE463_16375	ENOG4105VEQ	Cold shock protein
CE463_16400	ENOG4105CPP	Dehydrogenase, E1 component
CE463_16405	ENOG4107RUY	(E1 component), alpha subunit
CE463_16420	ENOG4105KR1	Trans-acting protein required for termination of DNA replication. Binds to DNA replication terminator sequences (terA to terF) to prevent the passage of replication forks. The termination efficiency will be affected by the affinity of this protein for the terminator sequence (By similarity)
CE463_16430	ENOG4108YXG	UPF0502 protein
CE463_16445	ENOG410600T	transposase
CE463_16465	ENOG4105ESV	Glycosyl transferase, family 4
CE463_16480	ENOG410600T	transposase
CE463_16500	ENOG410600T	transposase
CE463_16525	ENOG4107EF8	Glycosyl transferase (Group 1
CE463_16535	ENOG4105EY8	ABC transporter
CE463_16545	ENOG4105GVR	general secretion pathway protein D
CE463_16575	ENOG4108VAU	general secretion pathway protein G
CE463_16580	ENOG4105D7Q	type ii secretion system
CE463_16585	ENOG4107QHF	type ii secretion system protein e
CE463_16595	ENOG4108URP	Dtdp-4-dehydrorhamnose 3,5-epimerase
CE463_16605	ENOG4105DBZ	Dtdp-4-dehydrorhamnose reductase
CE463_16610	ENOG4105C1B	dTDP-glucose 4-6-dehydratase
CE463_16615	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
CE463_16630	ENOG4108IG5	Transcriptional regulator
CE463_16645	ENOG4105C29	acyl-CoA thioesterase
CE463_16650	ENOG4105FE9	pseudouridine synthase
CE463_16655	ENOG4105K8I	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves (By similarity)
CE463_16665	ENOG4107RTD	sua5 ycio yrdc ywlc family protein
CE463_16670	ENOG4105DB7	PHP domain protein
CE463_16675	ENOG4105CRQ	synthase (Component I)
CE463_16680	ENOG4108EFP	Anthranilate synthase component II
CE463_16685	ENOG4108I0Q	anthranilate phosphoribosyltransferase
CE463_16690	ENOG4105DK0	Indole-3-glycerol phosphate synthase
CE463_16695	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
CE463_16700	ENOG4105F6H	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate (By similarity)
CE463_16755	ENOG4105DM4	PTS System
CE463_16765	ENOG4108YRF	PTS System
CE463_16775	ENOG4108R99	pseudouridine synthase
CE463_16785	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
CE463_16790	ENOG41075W9	High frequency lysogenization protein HflD homolog
CE463_16795	ENOG4107QTF	adenylosuccinate lyase
CE463_16800	ENOG4105EZE	Cupin 4 family protein
CE463_16850	ENOG4108RXX	maleylacetoacetate isomerase
CE463_16855	ENOG4108S7T	Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) (By similarity)
CE463_16875	ENOG4105M2J	Glutaredoxin
CE463_16880	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
CE463_16885	ENOG410903C	(LipO)protein
CE463_16895	ENOG4105KWW	Biogenesis protein
CE463_16900	ENOG4107QX9	Thiol disulfide interChange protein
CE463_16905	ENOG4105DA4	cytochrome c-type biogenesis protein
CE463_16910	ENOG4108ZKK	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH (By similarity)
CE463_16915	ENOG4105X3C	heme exporter protein
CE463_16920	ENOG41060IM	Heme exporter protein
CE463_16925	ENOG4105CA5	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes (By similarity)
CE463_16940	ENOG4108V3W	Chemotaxis protein, CheW
CE463_16950	ENOG4107QJE	Chromosome Partitioning Protein
CE463_16955	ENOG4108SEK	ompa motb domain protein
CE463_16965	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
CE463_16970	ENOG4105CBS	Chea signal transduction histidine kinase
CE463_16980	ENOG4105C5Q	Transcriptional regulator
CE463_16990	ENOG4108QBX	(LipO)protein
CE463_17000	ENOG4107RGH	Aldehyde dehydrogenase
CE463_17005	ENOG4108RZE	Tetr family transcriptional regulator
CE463_17025	ENOG4105C6T	cysteine synthase
CE463_17045	ENOG4105UQX	Mate efflux family protein
CE463_17055	ENOG4105Z2P	Protein of unknown function (DUF465)
CE463_17060	ENOG4105D95	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin (By similarity)
CE463_17075	ENOG4105QVC	MOSC domain-containing protein
CE463_17075	ENOG4105QVC	MOSC domain-containing protein
CE463_17080	ENOG4107SDU	Methyl-accepting chemotaxis
CE463_17085	ENOG4105D0M	Protease HtpX homolog
CE463_17090	ENOG4105E78	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity)
CE463_17095	ENOG410626R	Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity)
CE463_17100	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
CE463_17105	ENOG4105CZF	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism (By similarity)
CE463_17110	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
CE463_17125	ENOG4105C5S	asparaginyl-tRNA synthetase
CE463_17150	ENOG4105KUZ	arsenate reductase
CE463_17155	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
CE463_17170	ENOG4105C3N	Participates in control of cell volume in low-osmolarity conditions (By similarity)
CE463_17190	ENOG410600T	transposase
CE463_17195	ENOG4105QDK	Flavodoxin
CE463_17200	ENOG4105DR9	pseudouridine synthase
CE463_17205	ENOG4105WP7	tRNA pseudouridine synthase C
CE463_17230	ENOG4105EXF	Zn-ribbon-containing, possibly nucleic-acid-binding protein
CE463_17235	ENOG4108T6E	Interacts with the SecY protein in vivo. May bind preferentially to an uncomplexed state of SecY, thus functioning either as a chelating agent for excess SecY in the cell or as a regulatory factor that negatively controls the translocase function (By similarity)
CE463_17240	ENOG4107R1K	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) (By similarity)
CE463_17250	ENOG4105BZU	Histidine kinase
CE463_17255	ENOG4105EWT	decarboxylase family
CE463_17260	ENOG4105CIQ	May have a role in processing of nucleic acids. It is probably not an exonuclease
CE463_17265	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
CE463_17275	ENOG4105EZ6	Catalyzes the 2'-O-methylation at nucleotide C2498 in 23S rRNA (By similarity)
CE463_17280	ENOG4105M08	Membrane
CE463_17290	ENOG4105ETT	transcriptional Regulator, LysR family
CE463_17295	ENOG4105C8Q	Methyl-accepting chemotaxis
CE463_17300	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
CE463_17315	ENOG4105CJ2	(LipO)protein
CE463_17320	ENOG4105D26	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. The first step is catalyzed by NqrF, which accepts electrons from NADH and reduces ubiquinone-1 to ubisemiquinone by a one-electron transfer pathway (By similarity)
CE463_17325	ENOG4108IUB	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
CE463_17330	ENOG4105F5D	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
CE463_17335	ENOG4106I92	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
CE463_17340	ENOG4108J5C	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
CE463_17345	ENOG4105DWQ	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
CE463_17350	ENOG4105M85	Bola protein
CE463_17360	ENOG4105D8J	Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle (By similarity)
CE463_17370	ENOG4108R5K	PPIases accelerate the folding of proteins (By similarity)
CE463_17380	ENOG4105EYM	Major Facilitator superfamily
CE463_17385	ENOG4105DRB	nucleoside-specific channel-forming protein
CE463_17390	ENOG4108VPT	UPF0234 protein
CE463_17395	ENOG4108JZF	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity)
CE463_17400	ENOG4107S0N	DJ-1 family
CE463_17405	ENOG4105C7K	acetolactate synthase
CE463_17420	ENOG4105E2V	Glycosyltransferase 36
CE463_17435	ENOG4105DRC	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity)
CE463_17440	ENOG4105CMR	udp-glucose 4-epimerase
CE463_17450	ENOG4105EJ7	Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O (By similarity)
CE463_17455	ENOG4108RMU	ferritin dps family protein
CE463_17480	ENOG4105CV9	cyclopropane-fatty-acyl-phospholipid synthase
CE463_17495	ENOG4107FW0	short-chain dehydrogenase reductase
CE463_17505	ENOG4105CVP	deoxyribo-dipyrimidine photolyase
CE463_17510	ENOG4108XDN	Transcriptional regulator
CE463_17515	ENOG4107SEY	Conserved Protein
CE463_17545	ENOG4105CQC	Prephenate dehydratase
CE463_17595	ENOG4105E1F	short-chain dehydrogenase reductase
CE463_17620	ENOG4105CTD	carboxy-peptidase
CE463_17635	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
CE463_17645	ENOG4105XDF	Protein of unknown function (DUF1272)
CE463_17660	ENOG4105N14	lysine exporter protein LysE YggA
CE463_17670	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
CE463_17680	ENOG4108VYJ	response regulator receiver protein
CE463_17700	ENOG4108V3W	Chemotaxis protein, CheW
CE463_17705	ENOG4105C8Q	Methyl-accepting chemotaxis
CE463_17710	ENOG4105BZU	Histidine kinase
CE463_17735	ENOG410600T	transposase
CE463_17740	ENOG4105EZV	Transcriptional regulator
CE463_17750	ENOG4105CJP	fad dependent oxidoreductase
CE463_17755	ENOG4107VRI	Transcriptional regulator
CE463_17760	ENOG4105C26	Dehydrogenase
CE463_17765	ENOG4108JPW	Aminotransferase
CE463_17770	ENOG4105CUB	amino acid
CE463_17775	ENOG4105CUB	amino acid
CE463_17785	ENOG4108V1T	peptidylprolyl cis-trans isomerase
CE463_17790	ENOG4105C8E	extradiol ring-cleavage dioxygenase class IIi protein subunit b
CE463_17805	ENOG4108QW8	Purine nucleoside phosphorylase deoD-type
CE463_17830	ENOG4105D98	threonine synthase
CE463_17835	ENOG4105D5I	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate (By similarity)
CE463_17845	ENOG4106FVC	RNA methyltransferase
CE463_17850	ENOG4105VS7	Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue. This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon. When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation (By similarity)
CE463_17865	ENOG4108YYX	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. Modulates RNA-binding and helicase activities of the degradosome (By similarity)
CE463_17875	ENOG41065U4	response regulator
CE463_17890	ENOG4108JJ9	ABC, transporter
CE463_17895	ENOG4108JJ8	(ABC) transporter
CE463_17915	ENOG4108R96	Methyltransferase, YaeB family
CE463_17935	ENOG4105C6T	cysteine synthase
CE463_17940	ENOG4105KZ7	phosphocarrier protein hpr
CE463_17950	ENOG4105C5Y	PTS System
CE463_17955	ENOG4105BZU	Histidine kinase
CE463_17965	ENOG4105CPW	cytochrome b561
CE463_17975	ENOG410600T	transposase
CE463_17985	ENOG4105EYH	Exonuclease
CE463_17990	ENOG4107RH8	nuclease SbcCD subunit D
CE463_18000	ENOG4105DH7	May be involved in recombination (By similarity)
CE463_18005	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
CE463_18010	ENOG4105CKD	glutathione-regulated potassium-efflux system protein
CE463_18015	ENOG4105CKD	glutathione-regulated potassium-efflux system protein
CE463_18030	ENOG4105CA9	Pyruvate kinase
CE463_18035	ENOG4105EGS	Mechanosensitive ion channel
CE463_18055	ENOG4108US0	Transcription regulator that can specifically activate or repress expression of target genes (By similarity)
CE463_18060	ENOG4105J12	Multidrug resistance protein mdtN
CE463_18085	ENOG4108RDD	Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine (By similarity)
CE463_18095	ENOG4105CJD	(Anaerobic) ribonucleoside-triphosphate reductase
CE463_18105	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
CE463_18115	ENOG4105CDB	Required for chromosome condensation and partitioning (By similarity)
CE463_18120	ENOG4105EXN	Sulfate transport protein CysZ
CE463_18125	ENOG4105EN6	Membrane
CE463_18135	ENOG4105EAQ	(twin-arginine translocation) pathway signal
CE463_18140	ENOG4105DIT	ErfK YbiS YcfS YnhG family protein
CE463_18175	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
CE463_18180	ENOG4105DR5	peptidase
CE463_18185	ENOG4105ED7	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling (By similarity)
CE463_18190	ENOG4105KME	endoribonuclease L-psp
CE463_18205	ENOG410600T	transposase
CE463_18210	ENOG4105CV1	Transketolase (EC 2.2.1.1)
CE463_18215	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
CE463_18220	ENOG4105GPY	SprT protein
CE463_18230	ENOG4105QF0	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity)
CE463_18235	ENOG4105D7Z	glutathione synthase
CE463_18255	ENOG4108UJU	UPF0301 protein
CE463_18260	ENOG4107Y66	Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity)
CE463_18265	ENOG4105G2Y	Transcriptional regulator
CE463_18280	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
CE463_18290	ENOG4105F8C	transglutaminase domain-containing protein
CE463_18295	ENOG4105BZG	amino acid carrier protein
CE463_18300	ENOG4105CW3	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
CE463_18315	ENOG4105D5S	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine (By similarity)
CE463_18330	ENOG4108VKA	Acts as a radical domain for damaged PFL and possibly other radical proteins (By similarity)
CE463_18350	ENOG4105CXR	Phospho-2-dehydro-3-deoxyoctonate aldolase
CE463_18355	ENOG41063JG	Transcriptional regulator
CE463_18365	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
CE463_18370	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
CE463_18375	ENOG4105C7E	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) (By similarity)
CE463_18380	ENOG4105C1U	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein (By similarity)
CE463_18385	ENOG4105CTR	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol (By similarity)
CE463_18395	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
CE463_18400	ENOG4105CGH	5'-nucleotidase
CE463_18405	ENOG4108ZPD	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity)
CE463_18410	ENOG4105C3G	gtp-binding protein
CE463_18455	ENOG4107QWE	)-transporter
CE463_18460	ENOG4106Z1T	Nicotinamide Mononucleotide Transporter
CE463_18465	ENOG4108I5U	Uridine phosphorylase
CE463_18475	ENOG41060QA	UPF0267 protein
CE463_18500	ENOG4105F7F	Chaperone
CE463_18515	ENOG4105CG3	alpha amylase, catalytic region
CE463_18530	ENOG4105C5H	ABC transporter
CE463_18535	ENOG4107QF7	multi-drug
CE463_18550	ENOG4107VXZ	Hydrolase
CE463_18560	ENOG4105C26	Dehydrogenase
CE463_18570	ENOG4105C8Y	Acetylornithine aminotransferase
CE463_18575	ENOG4105DDQ	anthranilate synthase
CE463_18585	ENOG4105C31	Tryptophanyl-tRNA synthetase
CE463_18590	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
CE463_18595	ENOG4105DJV	ribulose-phosphate 3-epimerase
CE463_18600	ENOG4105DFE	Dna adenine methylase
CE463_18610	ENOG4105D49	3-dehydroquinate synthase
CE463_18615	ENOG4105KHV	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
CE463_18645	ENOG4108JQC	penicillin-binding protein 1A
CE463_18650	ENOG4105C5Q	Transcriptional regulator
CE463_18655	ENOG4105C8Q	Methyl-accepting chemotaxis
CE463_18670	ENOG4105EJC	lysr family transcriptional regulator
CE463_18685	ENOG4105DR5	peptidase
CE463_18715	ENOG4108QXE	glycerophosphoryl diester phosphodiesterase
CE463_18720	ENOG4105C8Q	Methyl-accepting chemotaxis
CE463_18730	ENOG4105E33	succinate dehydrogenase
CE463_18735	ENOG4108WJH	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane (By similarity)
CE463_18740	ENOG4108VP9	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane (By similarity)
CE463_18760	ENOG4105T0Z	Conserved Protein
CE463_18795	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
CE463_18800	ENOG4105DHQ	Histidine kinase
CE463_18810	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
CE463_18820	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
CE463_18830	ENOG4105C5I	Dehydrogenase
CE463_18850	ENOG4105EVE	HAD-superfamily hydrolase subfamily IA variant 3
CE463_18865	ENOG4105BZU	Histidine kinase
CE463_18870	ENOG4105VEQ	Cold shock protein
CE463_18875	ENOG4105EAK	ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family
CE463_18880	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
CE463_18885	ENOG4105C9A	Phoh family
CE463_18890	ENOG4105KGE	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA (By similarity)
CE463_18895	ENOG4108JU5	Magnesium and cobalt efflux protein
CE463_18905	ENOG4107PAI	alpha helical protein
CE463_18910	ENOG4105C8T	Leucyl-tRNA synthetase
CE463_18930	ENOG4108Z1W	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity)
CE463_18935	ENOG4105KEM	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation (By similarity)
CE463_18940	ENOG4108UXA	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA (By similarity)
CE463_18945	ENOG4105CJN	penicillin-binding protein
CE463_18950	ENOG4105CNI	cell division protein FtsW
CE463_18955	ENOG4105CVE	Lytic murein transglycosylase
CE463_18960	ENOG4105K6T	rare lipoprotein A
CE463_18965	ENOG4105DZ1	carboxypeptidase
CE463_18970	ENOG4108Z43	UPF0250 protein
CE463_18975	ENOG4108BDP	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity)
CE463_18985	ENOG4105C0G	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity)
CE463_19000	ENOG4108HK0	-acetyltransferase
CE463_19005	ENOG4105MJ9	esterase
CE463_19010	ENOG4108IUB	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
CE463_19020	ENOG4105C2R	Single-stranded-DNA-specific exonuclease (RecJ)
CE463_19030	ENOG4105M2E	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell (By similarity)
CE463_19035	ENOG4105BZU	Histidine kinase
CE463_19040	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
CE463_19045	ENOG41071R3	Low-potential electron donor to a number of redox enzymes (By similarity)
CE463_19065	ENOG4107N1Q	ErfK YbiS YcfS YnhG family protein
CE463_19100	ENOG410600T	transposase
CE463_19105	ENOG4105EQ6	Hydrolyzes dipeptides containing N-terminal aspartate residues. May play a role in allowing the cell to use peptide aspartate to spare carbon otherwise required for the synthesis of the aspartate family of amino acids (By similarity)
CE463_19115	ENOG4105WAY	exported protein
CE463_19120	ENOG41090EX	DsrE family
CE463_19125	ENOG4105BZU	Histidine kinase
CE463_19130	ENOG4105E5W	Transporter
CE463_19135	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
CE463_19140	ENOG4105K77	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity)
CE463_19145	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
CE463_19150	ENOG4105KG7	Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity)
CE463_19155	ENOG4107QHU	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
CE463_19160	ENOG4105CHV	Transcription elongation factor NusA
CE463_19165	ENOG4105K7D	Required for maturation of 30S ribosomal subunits (By similarity)
CE463_19185	ENOG4105CP7	Triose-phosphate isomerase
CE463_19190	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
CE463_19195	ENOG4105EEI	dihydropteroate synthase
CE463_19200	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
CE463_19205	ENOG4105F7M	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit (By similarity)
CE463_19210	ENOG4105HBR	Rna-binding protein
CE463_19220	ENOG4108UKH	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
CE463_19235	ENOG4107XSU	flagellar motor protein motb
CE463_19240	ENOG4105E14	MotA TolQ exbB proton channel
CE463_19245	ENOG41067QG	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
CE463_19250	ENOG4105CTB	Polyprenyl synthetase
CE463_19255	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
CE463_19265	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
CE463_19275	ENOG4108JQ6	ABC transporter
CE463_19280	ENOG4108ZAI	phosphatidylglycerophosphatase a
CE463_19285	ENOG4105CG2	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity)
CE463_19290	ENOG4107YIM	Involved in the transcription termination process (By similarity)
CE463_19295	ENOG4108UTT	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity)
CE463_19310	ENOG4105D1W	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity)
CE463_19315	ENOG4108Z11	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes (By similarity)
CE463_19330	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
CE463_19350	ENOG4109039	Involved in the biogenesis of TorA. Acts on TorA before the insertion of the molybdenum cofactor and, as a result, probably favors a conformation of the apoenzyme that is competent for acquiring the cofactor (By similarity)
CE463_19370	ENOG4105BZU	Histidine kinase
CE463_19380	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
CE463_19385	ENOG4108Z38	Catalyzes a trans-dehydration via an enolate intermediate (By similarity)
CE463_19390	ENOG4105KM4	Acetyl-CoA carboxylase, biotin carboxyl carrier protein
CE463_19395	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
CE463_19400	ENOG4105RG0	Membrane
CE463_19405	ENOG4108IA2	Sodium pantothenate symporter
CE463_19410	ENOG4105CI1	PTS System
CE463_19415	ENOG4105HEI	LysR family (Transcriptional regulator
CE463_19420	ENOG4105CIS	alcohol dehydrogenase
CE463_19425	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
CE463_19430	ENOG4105CUB	amino acid
CE463_19435	ENOG4105CPD	ethanolamine ammonia-lyase
CE463_19440	ENOG4107FQ9	ethanolamine ammonia-lyase
CE463_19460	ENOG41069NU	Nitroreductase
CE463_19465	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
CE463_19470	ENOG4105D07	Signal peptide peptidase, SppA
CE463_19490	ENOG4105VUT	cytoplasmic protein
CE463_19495	ENOG4105HDK	L-asparaginase
CE463_19500	ENOG4105D6U	Sodium Glutamate Symporter
CE463_19505	ENOG4105C8Q	Methyl-accepting chemotaxis
CE463_19515	ENOG4105CRK	lysyL-tRNA synthetase
CE463_19520	ENOG4107TIF	Phenazine biosynthesis protein, PhzF family
CE463_19525	ENOG4107EER	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity)
CE463_19530	ENOG4105ET1	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate (By similarity)
CE463_19535	ENOG4105ET3	Reduction of activated sulfate into sulfite (By similarity)
CE463_19540	ENOG4105GIJ	Glycine betaine
CE463_19545	ENOG4108HQS	Glycine betaine
CE463_19550	ENOG4108IJ7	Glycine betaine
CE463_19560	ENOG4107XM3	UPF0442 protein
CE463_19565	ENOG4105DWK	Membrane
CE463_19580	ENOG4108RIR	Molybdenum cofactor biosynthesis protein
CE463_19590	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
CE463_19595	ENOG4105C2D	reductase
CE463_19605	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
CE463_19630	ENOG4105C84	Histidine ammonia-lyase
CE463_19645	ENOG4108KW7	amp-dependent synthetase and ligase
CE463_19660	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
CE463_19705	ENOG4105CA0	peroxidase
CE463_19710	ENOG410600T	transposase
CE463_19720	ENOG4105D53	Catalyzes the hydrolysis of pseudouridine 5'-phosphate (PsiMP) to ribose 5-phosphate and uracil (By similarity)
CE463_19725	ENOG4105DD7	kinase (PfkB family
CE463_19755	ENOG4105C2S	Catalyzes the NADPH dependent reduction of L-gamma- glutamyl 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate (By similarity)
CE463_19760	ENOG4105CGT	Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity)
CE463_19770	ENOG4105V1F	Fermentation respiration switch protein
CE463_19775	ENOG4105DYA	Acts on guanine, xanthine and to a lesser extent hypoxanthine (By similarity)
CE463_19790	ENOG4105CIN	aminoacyl-histidine dipeptidase
CE463_19800	ENOG4108JQ7	(ABC) transporter
CE463_19810	ENOG4107QRA	Extracellular solute-binding protein, family 5
CE463_19815	ENOG4108IYQ	Binding-protein-dependent transport systems inner membrane component
CE463_19835	ENOG410600T	transposase
CE463_19860	ENOG4109015	Biopolymer transport protein exbD tolR
CE463_19915	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
CE463_19930	ENOG4105VEQ	Cold shock protein
CE463_19970	ENOG4108RBP	3'-to-5' exoribonuclease specific for small oligoribonucleotides (By similarity)
CE463_19980	ENOG4105DJ4	phosphatidylserine decarboxylase
CE463_19985	ENOG4105VYA	Uncharacterized conserved protein (DUF2132)
CE463_20005	ENOG4105BZU	Histidine kinase
CE463_20010	ENOG4105KQT	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome (By similarity)
CE463_20015	ENOG4107G87	m6 family metalloprotease domain protein
CE463_20040	ENOG4105CZ6	Can catalyze the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine (By similarity)
CE463_20045	ENOG4105C26	Dehydrogenase
CE463_20060	ENOG4105BZ1	(ABC) transporter
CE463_20065	ENOG4105SUV	lipoprotein YgdR
CE463_20070	ENOG4107RM6	sulfurtransferase
CE463_20075	ENOG4105CSV	Glutaminase
CE463_20080	ENOG41090ED	Protein with unknown function (DUF469)
CE463_20085	ENOG4105CZ1	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity)
CE463_20090	ENOG4105IIU	Aminopeptidase
CE463_20095	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
CE463_20100	ENOG4105BZU	Histidine kinase
CE463_20105	ENOG4105ECP	epimerase
CE463_20110	ENOG4105CV6	ABC transporter, permease
CE463_20115	ENOG4108I0Y	(ABC) transporter
CE463_20120	ENOG4108UJV	acyl-CoA thioesterase i
CE463_20125	ENOG4107R88	Chemotaxis protein (CheV)
CE463_20135	ENOG4105D0C	transport protein
CE463_20140	ENOG4108UT2	hemolysin iii
CE463_20145	ENOG4105DY8	decarboxylase
CE463_20150	ENOG4107835	probably involved in intracellular septation (By similarity)
CE463_20155	ENOG4105K9H	YciI-like protein
CE463_20160	ENOG4108RNI	3'(2')5'-bisphosphate nucleotidase
CE463_20165	ENOG41083P1	competence protein ComEA helix-hairpin-helix repeat protein
CE463_20170	ENOG4105C3Y	UTP-glucose-1-phosphate uridylyltransferase
CE463_20175	ENOG4105DUX	Transporter
CE463_20180	ENOG4105I93	response regulator
CE463_20210	ENOG4107V40	secretion protein, HlyD family
CE463_20220	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
CE463_20225	ENOG4105VY0	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters (By similarity)
CE463_20230	ENOG410829K	Lysine exporter protein (Lyse ygga)
CE463_20290	ENOG4107V4F	S-adenosyl-l-methionine hydroxide adenosyltransferase
CE463_20310	ENOG4105C1J	atp-dependent rna helicase
CE463_20320	ENOG4107YH7	Beta-lactamase (EC 3.5.2.6)
CE463_20430	ENOG4107635	Hok Gef family protein
CE463_20450	ENOG4105DFP	Integrase
CE463_20465	ENOG4108K5H	permease YjgP YjgQ family protein
CE463_20470	ENOG4108M8S	permease YjgP YjgQ family protein
CE463_20475	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
CE463_20480	ENOG4105MYG	DNA polymerase iii, chi subunit
CE463_20495	ENOG4106W5V	Membrane
CE463_20500	ENOG41061WM	D-Alanyl-D-Alanine
CE463_20525	ENOG4105VM8	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding (By similarity)
CE463_20530	ENOG4105CFH	Aspartokinase
CE463_20535	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
CE463_20545	ENOG4105C68	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity)
CE463_20550	ENOG4107TH8	cina domain protein
CE463_20555	ENOG4108Z66	YbaK ebsC protein
CE463_20595	ENOG41067MG	lrgb family
CE463_20610	ENOG4105CFH	Aspartokinase
CE463_20615	ENOG4105C28	cystathionine
CE463_20620	ENOG4105GGQ	This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis (By similarity)
CE463_20630	ENOG4108Z7R	Chaperone CsaA
CE463_20635	ENOG4105C44	Serine transporter
CE463_20640	ENOG4108RNI	3'(2')5'-bisphosphate nucleotidase
CE463_20645	ENOG4107RK2	ADP-ribose diphosphatase NudE
CE463_20650	ENOG4107Y3D	HAD-superfamily hydrolase subfamily IA variant 3
CE463_20655	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
CE463_20660	ENOG4108UDW	Transcriptional regulator, luxr family
CE463_20700	ENOG4108VAU	general secretion pathway protein G
CE463_20705	ENOG4105D7Q	type ii secretion system
CE463_20710	ENOG4107QHF	type ii secretion system protein e
CE463_20715	ENOG4105GVR	general secretion pathway protein D
CE463_20720	ENOG4108XKW	General secretion pathway protein C
CE463_20725	ENOG4105VEJ	Heat shock protein
CE463_20730	ENOG4105F4C	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress (By similarity)
CE463_20735	ENOG4105DJ1	Phosphoenolpyruvate Carboxylase
CE463_20750	ENOG4105VXR	cytoplasmic protein
CE463_20755	ENOG4108R6G	acetyltransferase
CE463_20760	ENOG4108XTF	Outer Membrane Lipoprotein
CE463_20765	ENOG4107RNS	bifunctional 2',3'-cyclic nucleotide 2'-phosphodiesterase 3'-nucleotidase periplasmic
CE463_20770	ENOG4108ZUB	Lysine exporter protein (Lyse ygga)
CE463_20775	ENOG4105VJY	transcriptional regulator
CE463_20780	ENOG4105NNS	Autoinducer synthesis protein
CE463_20785	ENOG4105CXD	Specific inhibitor of chromosomal initiation of replication in vitro. Binds the three 13-mers in the origin (oriC) to block initiation of replication (By similarity)
CE463_20790	ENOG4108IEC	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction (By similarity)
CE463_20805	ENOG4105CTS	PTS system mannitol-specific
CE463_20810	ENOG4107SQ3	mannitol-1-phosphate 5-dehydrogenase
CE463_20815	ENOG4105E61	Mannitol repressor protein
CE463_20820	ENOG4105C3N	Participates in control of cell volume in low-osmolarity conditions (By similarity)
CE463_20825	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
CE463_20845	ENOG4108UPT	UPF0178 protein
CE463_20860	ENOG4107K5X	Membrane-bound metal-dependent hydrolase
CE463_20865	ENOG4105D9N	nucleoside
CE463_20875	ENOG4105C1J	atp-dependent rna helicase
CE463_20900	ENOG4105EIS	1,4-dihydroxy-2-naphthoate octaprenyltransferase
CE463_20905	ENOG4105E4F	Isochorismate synthase
CE463_20910	ENOG4105C4A	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC) (By similarity)
CE463_20915	ENOG4107J5P	Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC). Is also able to catalyze the hydrolysis of the thioester bond in palmitoyl-CoA in vitro (By similarity)
CE463_20920	ENOG4108IPT	Naphthoate synthase
CE463_20925	ENOG4105DNI	Converts SHCHC to OSB (By similarity)
CE463_20930	ENOG4105CEY	Amp-dependent synthetase and ligase
CE463_20940	ENOG410600T	transposase
CE463_21005	ENOG410600T	transposase
CE463_21025	ENOG4108UB4	uncharacterized protein ygjQ
CE463_21030	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
CE463_21040	ENOG4107IFA	Lipase (EC 3.1.1.3)
CE463_21060	ENOG4105C1X	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity (By similarity)
CE463_21075	ENOG4108IQK	o-acetylhomoserine
CE463_21100	ENOG4105DZW	Dipeptidase
CE463_21105	ENOG4105EMU	Dehydrogenase
CE463_21125	ENOG4105KT7	mgtC SapB transporter
CE463_21145	ENOG4105E0M	Sulfatase
CE463_21150	ENOG4108YXU	transcriptional regulator AsnC family
CE463_21160	ENOG4105CVG	Homoserine O-transsuccinylase
CE463_21165	ENOG4105E4Y	Endoribonuclease that initiates mRNA decay (By similarity)
CE463_21170	ENOG4108I62	cina-like protein
CE463_21180	ENOG4105CJ1	ABC, transporter
CE463_21205	ENOG410667J	hydrolase
CE463_21210	ENOG4108Z86	Glutamine amidotransferase
CE463_21220	ENOG4105D64	Mechanosensitive ion channel
CE463_21230	ENOG4105DFC	had-superfamily hydrolase, subfamily ia, variant
CE463_21235	ENOG4108IYS	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
CE463_21245	ENOG4105E4Z	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan (By similarity)
CE463_21250	ENOG4105CU5	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity)
CE463_21255	ENOG4105XQ6	frataxin-like protein
CE463_21260	ENOG4106CJB	Phospholipase Carboxylesterase
CE463_21265	ENOG4107T0K	Adenylate cyclase
CE463_21270	ENOG4105D6W	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity)
CE463_21275	ENOG41076E6	Uroporphyrinogen-III Synthase
CE463_21280	ENOG4105ECF	c-methyltransferase
CE463_21295	ENOG4105CBT	Fructose-1,6-bisphosphatase
CE463_21310	ENOG4105E0K	tonB-dependent siderophore receptor
CE463_21335	ENOG4105N0V	mono-oxygenase ydhR
CE463_21345	ENOG4108TPP	exopolysaccharide synthesis
CE463_21350	ENOG4105C44	Serine transporter
CE463_21355	ENOG410600T	transposase
CE463_21385	ENOG4105D41	biosynthesis protein thiH
CE463_21390	ENOG4105CA8	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity)
CE463_21400	ENOG4105D06	uba thif-type nad fad binding protein
CE463_21405	ENOG4108UV6	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity)
CE463_21410	ENOG4105CBF	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction (By similarity)
CE463_21510	ENOG4105D5G	Transposase
CE463_21520	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
CE463_21525	ENOG4105DWY	Agmatine deiminase
CE463_21535	ENOG4108RZ4	Short-chain dehydrogenase reductase Sdr
CE463_21550	ENOG41060WC	Enoyl-CoA hydratase
CE463_21555	ENOG4106WH9	Protein of unknown function (DUF2753)
CE463_21560	ENOG4105EQK	-acetyltransferase
CE463_21570	ENOG4107QSI	ABC, transporter
CE463_21585	ENOG4105VZ9	UPF0235 protein
CE463_21590	ENOG4108VIA	integral membrane protein
CE463_21595	ENOG4105II7	pyrroline-5-carboxylate reductase
CE463_21600	ENOG4105DFA	alanine racemase domain protein
CE463_21605	ENOG4105CZX	twitching motility protein
CE463_21610	ENOG4105CZX	twitching motility protein
CE463_21615	ENOG4105D1Q	UPF0246 protein
CE463_21620	ENOG4105C1J	atp-dependent rna helicase
CE463_21625	ENOG4107S47	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC) (By similarity)
CE463_21630	ENOG4105CWM	branched-chain amino acid transport system II carrier protein
CE463_21645	ENOG4105MYN	Zinc uptake regulation protein
CE463_21650	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
CE463_21665	ENOG4105K70	DNA-binding protein
CE463_21670	ENOG4108ZVW	Anti-RNA polymerase sigma 70 factor
CE463_21680	ENOG4105DNJ	May play a role in the repair of endogenous alkylation damage (By similarity)
CE463_21695	ENOG4105EAC	phosphoserine phosphatase
CE463_21705	ENOG4105D3A	purine nucleoside phosphorylase DeoD-type
CE463_21710	ENOG4105CZG	Phosphotransfer between the C1 and C5 carbon atoms of pentose (By similarity)
CE463_21715	ENOG4105CMW	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis (By similarity)
CE463_21720	ENOG4105FCI	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate (By similarity)
CE463_21735	ENOG4105EYA	deoxyribonuclease
CE463_21750	ENOG4105VDT	-acetyltransferase
CE463_21755	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
CE463_21760	ENOG4105BZU	Histidine kinase
CE463_21795	ENOG4105ETX	regulatoR
CE463_21805	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
CE463_21820	ENOG4105EEQ	Na H antiporter
CE463_21835	ENOG4108HU6	Metal dependent phosphohydrolase
CE463_21845	ENOG4105F0S	class B acid phosphatase
CE463_21850	ENOG4107SDU	Methyl-accepting chemotaxis
CE463_21855	ENOG4107MMM	Anti-sigma-factor antagonist
CE463_21860	ENOG4105QD0	anti-sigma regulatory factor serine threonine protein kinase
CE463_21865	ENOG4105BZU	Histidine kinase
CE463_21870	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
CE463_21880	ENOG4105CSH	Transporter
CE463_21895	ENOG4105D1U	peptidase U62 modulator of DNA gyrase
CE463_21910	ENOG4105QD6	exported protein
CE463_21915	ENOG4105C03	ribonuclease
CE463_21920	ENOG4108Z03	MAF-like protein
CE463_21925	ENOG4105VQ7	Rod shape-determining protein MreD
CE463_21930	ENOG4105N3I	Involved in formation and maintenance of cell shape (By similarity)
CE463_21935	ENOG4105DFF	Rod shape-determining protein mreb
CE463_21965	ENOG4105GVR	general secretion pathway protein D
CE463_21995	ENOG41062P1	Diguanylate cyclase phosphodiesterase
CE463_22000	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
CE463_22005	ENOG4105EWV	Sodium calcium exchanger membrane region
CE463_22010	ENOG4105C84	Histidine ammonia-lyase
CE463_22015	ENOG4105CGP	Urocanate hydratase
CE463_22020	ENOG41088SP	formiminoglutamate hydrolase
CE463_22025	ENOG4105CI2	imidazolone-5-propionate hydrolase
CE463_22030	ENOG4105CZE	histidine utilization repressor
CE463_22035	ENOG41077A9	carbonic anhydrase
CE463_22040	ENOG4105DEK	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
CE463_22045	ENOG4105CRP	Part of the ABC transporter FtsEX involved in
CE463_22050	ENOG4105CAK	Cell division ATP-binding protein ftsE
CE463_22055	ENOG4105CCP	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
CE463_22060	ENOG4106H78	methyltransferase
CE463_22075	ENOG4105EJ2	Transcriptional regulator
CE463_22085	ENOG4107RZC	phospholipase d
CE463_22090	ENOG4105CHQ	Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella (By similarity)
CE463_22100	ENOG4105WKS	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity)
CE463_22110	ENOG41076UM	multiple antibiotic resistance (MarC)-related protein
CE463_22115	ENOG4105VVZ	metal-binding protein
CE463_22130	ENOG4105JQN	Transcriptional regulator
CE463_22145	ENOG4107FS9	Membrane
CE463_22165	ENOG4105CUG	Oligopeptidase b
CE463_22180	ENOG4108K2R	Glutathione-regulated potassium-efflux system ancillary protein
CE463_22185	ENOG4105CKD	glutathione-regulated potassium-efflux system protein
CE463_22215	ENOG4105D00	flagellar biosynthetic protein flhB
CE463_22220	ENOG4105D19	Role in flagellar biosynthesis (By similarity)
CE463_22225	ENOG4105VS8	Flagellar biosynthetic protein fliq
CE463_22230	ENOG4105CN7	Flagellar biosynthetic protein FliP
CE463_22235	ENOG4105DD5	Flagellar motor switch protein
CE463_22250	ENOG4105CU0	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity)
CE463_22255	ENOG4105E1C	Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1A (PBP1a) (By similarity)
CE463_22260	ENOG41082RQ	UPF0102 protein
CE463_22265	ENOG4105F55	Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate (By similarity)
CE463_22270	ENOG4105W4M	Transport-associated protein
CE463_22275	ENOG4105KB2	stringent starvation protein b
CE463_22280	ENOG4107MKT	Stringent starvation protein a
CE463_22285	ENOG4105EIX	cytochrome c1
CE463_22290	ENOG4105DJ5	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
CE463_22295	ENOG4108R5F	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
CE463_22300	ENOG4108UJD	30S ribosomal protein S9
CE463_22305	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
CE463_22310	ENOG4105D6Z	AFG1 family ATPase
CE463_22320	ENOG4105C0H	protease
CE463_22325	ENOG4105C0H	protease
CE463_22360	ENOG41069H0	dihydroorotase EC 3.5.2.3
CE463_22375	ENOG4105CTS	PTS system mannitol-specific
CE463_22380	ENOG41080Z8	PHOSPHOCARRIER protein
CE463_22385	ENOG4105C21	Displays ATPase and GTPase activities (By similarity)
CE463_22390	ENOG4107RM2	PTS IIA-like nitrogen-regulatory protein PtsN
CE463_22395	ENOG41080QH	sigma 54 modulation protein ribosomal protein S30EA
CE463_22400	ENOG4105DTW	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
CE463_22405	ENOG4108IUZ	ABC transporter
CE463_22410	ENOG4105WI0	lipopolysaccharide transport periplasmic protein lptA
CE463_22415	ENOG4108P1K	Required for the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane (By similarity)
CE463_22420	ENOG4108Z4R	3-deoxy-d-manno-octulosonate 8-phosphate phosphatase
CE463_22425	ENOG4105C2X	Arabinose 5-phosphate isomerase
CE463_22430	ENOG4105DHJ	ABC, transporter
CE463_22435	ENOG4105CY3	ABC transporter, permease
CE463_22440	ENOG4107PE3	Mammalian cell entry related domain protein
CE463_22445	ENOG4105E3I	toluene tolerance
CE463_22455	ENOG4105VFK	BolA family
CE463_22460	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
CE463_22465	ENOG4105CMS	peptidase U62, modulator of DNA gyrase
CE463_22470	ENOG4105N42	UPF0307 protein
CE463_22480	ENOG41090HJ	UPF0265 protein
CE463_22520	ENOG4108ZT0	50S ribosomal protein l17
CE463_22525	ENOG4105CTF	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
CE463_22530	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
CE463_22535	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
CE463_22540	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
CE463_22545	ENOG41067V7	50S ribosomal protein L36
CE463_22550	ENOG4105CGG	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity)
CE463_22555	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
CE463_22560	ENOG4105VPB	50S ribosomal protein L30
CE463_22565	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
CE463_22570	ENOG4105K4C	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity)
CE463_22575	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
CE463_22580	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
CE463_22585	ENOG4105VBI	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
CE463_22590	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
CE463_22595	ENOG4105KAR	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity)
CE463_22600	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
CE463_22605	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
CE463_22610	ENOG41083MP	50s ribosomal protein l29
CE463_22615	ENOG4108R70	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity)
CE463_22620	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
CE463_22625	ENOG4105KAP	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity)
CE463_22630	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
CE463_22635	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
CE463_22640	ENOG41080KG	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
CE463_22645	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
CE463_22650	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
CE463_22655	ENOG4108Z10	Involved in the binding of tRNA to the ribosomes (By similarity)
CE463_22665	ENOG4105E0F	Histidine kinase
CE463_22670	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
CE463_22675	ENOG4108RRZ	Transcription elongation factor GreB
CE463_22680	ENOG4105BZM	domain protein
CE463_22700	ENOG4105D3C	The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters (By similarity)
CE463_22705	ENOG4105MJ2	Competence protein
CE463_22710	ENOG4107RUK	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins (By similarity)
CE463_22715	ENOG4105CSF	NADPH-dependent glycerol-3-phosphate dehydrogenase
CE463_22720	ENOG4105IX2	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA (By similarity)
CE463_22725	ENOG4107YZP	Rhodanese domain protein
CE463_22730	ENOG4105CJI	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
CE463_22735	ENOG41063SB	peptidase
CE463_22745	ENOG4105DIQ	Transcriptional regulator
CE463_22750	ENOG4108UHU	Aldolase
CE463_22755	ENOG4105C01	Dihydroxy-acid dehydratase
CE463_22760	ENOG4108Z67	carbohydrate kinase, thermoresistant glucokinase family
CE463_22765	ENOG4105C6Z	Gluconate
CE463_22770	ENOG4105JIM	Phosphatidylserine synthase
CE463_22775	ENOG4105CB5	ATP-dependent DNA helicase recG
CE463_22785	ENOG4105SUU	thioesterase domain
CE463_22795	ENOG4108YYA	Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine (By similarity)
CE463_22800	ENOG4107S2Z	UPF0761 membrane protein
CE463_22810	ENOG4105C5F	glutamine synthetase
CE463_22820	ENOG4105CUX	Signal transduction histidine kinase
CE463_22825	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
CE463_22830	ENOG4105EKD	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism (By similarity)
CE463_22835	ENOG4105D4P	Coproporphyrinogen iii oxidase
CE463_22840	ENOG4105XCT	Protein of unknown function (DUF2489)
CE463_22845	ENOG4105ZR3	A GTPase-activating protein (GAP) that modifies Der EngA GTPase function. May play a role in ribosome biogenesis (By similarity)
CE463_22850	ENOG4106RE7	Cytochrome
CE463_22855	ENOG4105WHM	Necessary for normal cell division and for the maintenance of normal septation (By similarity)
CE463_22860	ENOG4105SG3	Protein of unknown function (DUF1488)
CE463_22865	ENOG4105E2X	shikimate dehydrogenase
CE463_22870	ENOG4105DBS	Key enzyme in heme biosynthesis. Catalyzes the oxidative decarboxylation of propionic acid side chains of rings A and B of coproporphyrinogen III (By similarity)
CE463_22875	ENOG4105EK0	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
CE463_22885	ENOG4108WI1	Dna topoisomerase
CE463_22890	ENOG4108RPN	Protein smg homolog
CE463_22895	ENOG4105C79	DNA protecting protein DprA
CE463_22900	ENOG4108WZM	domain protein
CE463_22905	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
CE463_22910	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
CE463_22915	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
CE463_22920	ENOG4105C1A	potassium transporter peripheral membrane
CE463_22925	ENOG4105D37	Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA (By similarity)
CE463_22930	ENOG4105CGY	Dna recombination protein
CE463_22950	ENOG4108TFM	Kinase, PfkB family
CE463_22955	ENOG4105DCF	alanine dehydrogenase
CE463_22960	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
CE463_22965	ENOG4105C26	Dehydrogenase
CE463_22980	ENOG4105C26	Dehydrogenase
CE463_22990	ENOG4105FR1	rard protein
CE463_22995	ENOG4105ECQ	AraC Family Transcriptional Regulator
CE463_23005	ENOG4105C52	Atpase, p-type (Transporting), had superfamily, subfamily ic
CE463_23020	ENOG4105WZK	nitrite reductase NADPH small subunit
CE463_23025	ENOG4107V9H	nitrite transporter
CE463_23030	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
CE463_23035	ENOG4105CJW	magnesium transporter
CE463_23040	ENOG4108NVR	Methyl-accepting chemotaxis
CE463_23045	ENOG4108YYX	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. Modulates RNA-binding and helicase activities of the degradosome (By similarity)
CE463_23050	ENOG4105EX9	Membrane
CE463_23060	ENOG4105CNG	UPF0061 protein
CE463_23065	ENOG4105N7H	Cytochrome
CE463_23070	ENOG4105C9U	ATP-dependent DNA helicase RecQ
CE463_23075	ENOG4108VUY	thioesterase Superfamily protein
CE463_23095	ENOG4108RPX	mosc domain containing protein
CE463_23100	ENOG4105D38	putrescine abc transporter
CE463_23105	ENOG4105F38	ABC transporter, permease
CE463_23110	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
CE463_23115	ENOG4108HM4	ABC transporter
CE463_23125	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
CE463_23130	ENOG4105CFQ	glutamine synthetase
CE463_23135	ENOG4108V7X	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
CE463_23150	ENOG4105C5I	Dehydrogenase
CE463_23155	ENOG4105R8A	Heat shock protein
CE463_23170	ENOG4107R28	alpha amylase, catalytic region
CE463_23175	ENOG4105C5E	polysaccharide biosynthesis protein
CE463_23180	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
CE463_23205	ENOG4105CEY	Amp-dependent synthetase and ligase
CE463_23210	ENOG4105CHR	reductase
CE463_23225	ENOG4105F0R	Cytidylyltransferase
CE463_23235	ENOG4105D2T	synthase
CE463_23260	ENOG410600T	transposase
CE463_23270	ENOG4105EQQ	protein containing aminopeptidase domain
CE463_23305	ENOG4107R9T	Catalyzes the formation of 5-methyl-uridine at position 54 (m5U54) in all tRNAs (By similarity)
CE463_23310	ENOG4107EXC	regulatoR
CE463_23315	ENOG4105JJR	Histidine kinase
CE463_23325	ENOG4105C6K	Malic enzyme
CE463_23330	ENOG4105CGD	Nad-dependent epimerase dehydratase
CE463_23335	ENOG4105VFB	Binds the 23S rRNA (By similarity)
CE463_23340	ENOG4105C25	Primosomal protein n'
CE463_23350	ENOG4105XEA	Tetr family transcriptional regulator
CE463_23360	ENOG4105UYK	outer membrane protein a
CE463_23365	ENOG4105C7B	Threonine dehydratase
CE463_23370	ENOG4105C01	Dihydroxy-acid dehydratase
CE463_23375	ENOG4105CM2	brancheD-chain amino acid aminotransferase
CE463_23380	ENOG4105P3Y	Acetolactate synthase 2 regulatory subunit
CE463_23390	ENOG4105C0P	Mg chelatase subunit ChlI
CE463_23400	ENOG4105EWC	Purine nucleoside phosphorylase
CE463_23410	ENOG4108RWI	nicotinamidase
CE463_23415	ENOG4107RH7	Nicotinate phosphoribosyltransferase
CE463_23420	ENOG4105EHI	Phosphonate ABC transporter, periplasmic
CE463_23425	ENOG4108VA1	ABC transporter
CE463_23430	ENOG4105S7S	phosphonate abc transporter
CE463_23435	ENOG4108Z33	Thiol disulfide Interchange Protein
CE463_23440	ENOG4105E27	serine threonine protein kinase
CE463_23450	ENOG4105PC1	Conserved Protein
CE463_23460	ENOG4108Z6Z	Transcriptional regulator
CE463_23470	ENOG4107QP2	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
CE463_23480	ENOG4105DSJ	YicC domain protein
CE463_23495	ENOG4107J0A	lipopolysaccharide biosynthetic process
CE463_23515	ENOG4105CUI	Catalyzes the interconversion between ADP-D-glycero- beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose (By similarity)
CE463_23520	ENOG41062JF	Transcriptional regulator
CE463_23525	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
CE463_23530	ENOG4105CPQ	Dehydrogenase
CE463_23545	ENOG4105C4R	Atp-dependent dna helicase
CE463_23550	ENOG4105C9B	Cysteine desulfurase
CE463_23555	ENOG4105P9C	Participates in cysteine desulfuration mediated by SufS. Cysteine desulfuration mobilizes sulfur from L-cysteine to yield L-alanine and constitutes an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules. Functions as a sulfur acceptor for SufS, by mediating the direct transfer of the sulfur atom from the S-sulfanylcysteine of SufS, an intermediate product of cysteine desulfuration process (By similarity)
CE463_23560	ENOG4105CUZ	uba thif-type nad fad binding protein
CE463_23590	ENOG4108RR8	protoporphyrinogen oxidase
CE463_23595	ENOG4105D37	Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA (By similarity)
CE463_23600	ENOG4108ZK7	protein family UPF0029, Impact, N-terminal protein
CE463_23610	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
CE463_23615	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
CE463_23620	ENOG4105CHU	acetyl-coa acetyltransferase
CE463_23625	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
CE463_23630	ENOG4105E0F	Histidine kinase
CE463_23645	ENOG41082K8	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Interacts with IscS and stimulates its activity. Then, accepts a sulfur from IscS and transfers it in turn to TusD (By similarity)
CE463_23650	ENOG4105M4H	endoribonuclease L-psp
CE463_23655	ENOG4108ZG0	Ompa motb domain protein
CE463_23665	ENOG4108HMW	glycyl-tRNA synthetase, alpha subunit
CE463_23670	ENOG4105C38	Glycyl-tRNA synthetase beta subunit
CE463_23675	ENOG41090VV	Protein of unknown function (DUF2846)
CE463_23690	ENOG4105FDP	GntR family transcriptional regulator
CE463_23695	ENOG4108JUA	Transcriptional regulator
CE463_23705	ENOG4108EQM	faD-dependent pyridine nucleotide-disulfide oxidoreductase
CE463_23715	ENOG4105HEE	Binding Domain protein
CE463_23720	ENOG4105CIC	tryptophan-specific transport protein
CE463_23735	ENOG4105BZU	Histidine kinase
CE463_23765	ENOG4105D5G	Transposase
CE463_23790	ENOG4105F8D	glycoside hydrolase family 4
CE463_23795	ENOG4105ETE	Transcriptional regulator (LacI family
CE463_23800	ENOG4105CP9	extracellular ligand-binding receptor
CE463_23805	ENOG4105C32	Amino acid ABC transporter (Permease)
CE463_23810	ENOG4105CF8	branched-chain amino acid ABC transporter, permease
CE463_23815	ENOG4105C0Z	ABC transporter
CE463_23820	ENOG4108IV0	ABC, transporter
CE463_23835	ENOG4105M78	Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide (By similarity)
CE463_23850	ENOG4105W0Z	cytoplasmic protein
CE463_23855	ENOG4107QK7	reductase
CE463_23860	ENOG4105D3H	Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol (By similarity)
CE463_23870	ENOG4105C4P	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity)
CE463_23875	ENOG4105K63	Thioredoxin
CE463_23880	ENOG4105C1J	atp-dependent rna helicase
CE463_23885	ENOG4105C9X	ppx gppa phosphatase
CE463_23895	ENOG4105FFN	Specifically methylates the guanosine in position 1516 of 16S rRNA (By similarity)
CE463_23905	ENOG4105BZU	Histidine kinase
CE463_23910	ENOG4105DGW	oligopeptidase A
CE463_23915	ENOG4105D52	delta-aminolevulinic acid dehydratase
CE463_23920	ENOG4105F8V	Hydrolase, tatD family
CE463_23925	ENOG4105DCX	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity)
CE463_23930	ENOG4105X8U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation (By similarity)
CE463_23935	ENOG4105WKS	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity)
CE463_23940	ENOG4105CNK	Required, probably indirectly, for the hydroxylation of 2-octaprenylphenol to 2-octaprenyl-6-hydroxy-phenol, the fourth step in ubiquinone biosynthesis (By similarity)
CE463_23945	ENOG4105JC1	sterol-binding domain protein
CE463_23950	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
CE463_23955	ENOG4105WMR	Protein CrcB homolog
CE463_23960	ENOG4105DZC	cytosine deaminase
CE463_24000	ENOG410822N	TonB family
CE463_24005	ENOG4109015	Biopolymer transport protein exbD tolR
CE463_24025	ENOG4105VJY	transcriptional regulator
CE463_24030	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
CE463_24035	ENOG410804X	Transcriptional regulator
CE463_24040	ENOG4105E3W	Two component transcriptional regulator (Winged helix family
CE463_24055	ENOG4105CT7	inner membrane cred family protein
CE463_24060	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
CE463_24065	ENOG4105KNM	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
CE463_24070	ENOG4105C4J	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity)
CE463_24075	ENOG4105J80	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity)
CE463_24080	ENOG4105CDG	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity)
CE463_24085	ENOG4107S15	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
CE463_24090	ENOG4107Z6K	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
CE463_24095	ENOG4105KY6	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
CE463_24100	ENOG4105EE4	it plays a direct role in the translocation of protons across the membrane (By similarity)
CE463_24105	ENOG410684E	atp synthase
CE463_24110	ENOG4105FA0	parb-like partition protein
CE463_24115	ENOG4107QJE	Chromosome Partitioning Protein
CE463_24120	ENOG4105D28	Specifically methylates the N7 position of a guanine in 16S rRNA (By similarity)
CE463_24125	ENOG4107RE5	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity)
CE463_24130	ENOG4105QTB	Flavodoxin
CE463_24135	ENOG4105E0K	tonB-dependent siderophore receptor
CE463_24140	ENOG4105IBP	Cyclic peptide transporter
CE463_24145	ENOG4105E0A	ABC, transporter
CE463_24150	ENOG4105J76	Periplasmic binding protein
CE463_24155	ENOG4105S6R	Iron-hydroxamate transporter permease subunit
CE463_24170	ENOG4108IPW	abc transporter atp-binding protein
CE463_24200	ENOG4105CEY	Amp-dependent synthetase and ligase
CE463_24210	ENOG4105C0W	non-ribosomal peptide synthetase
CE463_24225	ENOG4105C1H	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity)
CE463_24230	ENOG4105DHW	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
CE463_24235	ENOG4105VAS	Could be involved in insertion of integral membrane proteins into the membrane (By similarity)
CE463_24240	ENOG4105NVJ	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme (By similarity)
CE463_24245	ENOG4105VG0	50S ribosomal protein l34
CE463_24250	ENOG4105CDA	abc transporter atp-binding protein
CE463_24255	ENOG4105E5Q	amino acid AbC transporter
CE463_24260	ENOG4105EAB	amino acid AbC transporter