locus-tag	class	description
CE463_00040	COG2974	May be involved in recombination
CE463_00080	COG1525	nuclease
CE463_00085	COG0776	regulation of translation
CE463_00110	COG1192	Involved in chromosome partitioning
CE463_00165	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
CE463_00170	COG1061	Type III restriction enzyme res subunit
CE463_00175	COG1002	Type II restriction enzyme, methylase subunits
CE463_00190	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
CE463_00330	COG0714	Associated with various cellular activities
CE463_00395	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CE463_00470	COG3267	Type II secretory pathway component ExeA
CE463_00470	COG3409	Peptidoglycan-binding domain 1 protein
CE463_00530	COG0778	Nitroreductase
CE463_00535	COG0583	DNA-binding transcription factor activity
CE463_00640	COG4974	Belongs to the 'phage' integrase family
CE463_00645	COG1396	sequence-specific DNA binding
CE463_00650	COG3550	peptidyl-serine autophosphorylation
CE463_00670	COG1660	Displays ATPase and GTPase activities
CE463_00735	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
CE463_00780	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
CE463_00815	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
CE463_00855	COG3039	Transposase
CE463_00870	COG1357	PFAM Pentapeptide repeats (8 copies)
CE463_00905	COG4644	lycopene metabolic process
CE463_00970	COG1695	Transcriptional regulator
CE463_00980	COG3316	Transposase and inactivated derivatives
CE463_01000	COG3173	Aminoglycoside phosphotransferase
CE463_01005	COG3316	Transposase and inactivated derivatives
CE463_01020	COG3316	Transposase and inactivated derivatives
CE463_01185	COG1192	Involved in chromosome partitioning
CE463_01205	COG2361	Protein of unknown function DUF86
CE463_01210	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
CE463_01360	COG3039	Transposase
CE463_01410	COG2003	Belongs to the UPF0758 family
CE463_01465	COG1192	Involved in chromosome partitioning
CE463_01485	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
CE463_01510	COG2916	Histone family protein nucleoid-structuring protein H-NS
CE463_01520	COG1192	Involved in chromosome partitioning
CE463_01530	COG3328	transposase activity
CE463_01560	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
CE463_01565	COG1317	bacterial-type flagellum organization
CE463_01655	COG0457	Tetratricopeptide repeat
CE463_01720	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
CE463_01725	COG4790	Type iii secretion
CE463_01730	COG4794	Type iii secretion
CE463_01735	COG4791	protein targeting
CE463_01740	COG4792	protein secretion
CE463_01775	COG1192	Involved in chromosome partitioning
CE463_01795	COG1484	DNA-dependent DNA replication
CE463_01905	COG1192	Involved in chromosome partitioning
CE463_01930	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
CE463_01935	COG2361	Protein of unknown function DUF86
CE463_02015	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
CE463_02020	COG0592	DNA-directed DNA polymerase activity
CE463_02030	COG0187	DNA topoisomerase II activity
CE463_02045	COG2378	regulation of single-species biofilm formation
CE463_02050	COG0071	Belongs to the small heat shock protein (HSP20) family
CE463_02055	COG0071	Belongs to the small heat shock protein (HSP20) family
CE463_02070	COG3977	Valine--pyruvate aminotransferase
CE463_02085	COG2814	Major facilitator Superfamily
CE463_02090	COG0745	RESPONSE REGULATOR receiver
CE463_02095	COG2205	protein histidine kinase activity
CE463_02120	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CE463_02125	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CE463_02125	COG4191	Histidine kinase
CE463_02130	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CE463_02135	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CE463_02140	COG1309	transcriptional regulator
CE463_02170	COG0561	phosphatase activity
CE463_02175	COG2267	carboxylic ester hydrolase activity
CE463_02180	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CE463_02185	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CE463_02190	COG1758	RNA polymerase activity
CE463_02195	COG0194	GDP metabolic process
CE463_02205	COG0859	PFAM glycosyl transferase family 9
CE463_02210	COG3642	lipopolysaccharide core region biosynthetic process
CE463_02250	COG0589	response to stress
CE463_02255	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
CE463_02265	COG1528	Iron-storage protein
CE463_02270	COG2081	HI0933 family
CE463_02295	COG5433	transposase activity
CE463_02320	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CE463_02320	COG2205	protein histidine kinase activity
CE463_02330	COG3275	phosphorelay sensor kinase activity
CE463_02335	COG3279	Response regulator of the LytR AlgR family
CE463_02340	COG2223	nitrite transmembrane transporter activity
CE463_02345	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
CE463_02350	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
CE463_02365	COG0583	DNA-binding transcription factor activity
CE463_02370	COG4206	TonB-dependent receptor
CE463_02375	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
CE463_02420	COG0583	DNA-binding transcription factor activity
CE463_02425	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
CE463_02430	COG0166	Belongs to the GPI family
CE463_02440	COG0668	transmembrane transport
CE463_02445	COG1309	transcriptional regulator
CE463_02450	COG0756	dUTP diphosphatase activity
CE463_02455	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
CE463_02460	COG2003	Belongs to the UPF0758 family
CE463_02465	COG0227	Belongs to the bacterial ribosomal protein bL28 family
CE463_02470	COG0267	Belongs to the bacterial ribosomal protein bL33 family
CE463_02480	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
CE463_02485	COG2990	Protein conserved in bacteria
CE463_02490	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
CE463_02495	COG0859	PFAM glycosyl transferase family 9
CE463_02500	COG0463	Glycosyl transferase, family 2
CE463_02505	COG0859	PFAM glycosyl transferase family 9
CE463_02510	COG1519	Transferase
CE463_02525	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CE463_02530	COG1609	Transcriptional regulator
CE463_02560	COG1580	Controls the rotational direction of flagella during chemotaxis
CE463_02565	COG3161	chorismate lyase activity
CE463_02570	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
CE463_02575	COG2937	Belongs to the GPAT DAPAT family
CE463_02580	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
CE463_02595	COG0534	Mate efflux family protein
CE463_02600	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
CE463_02605	COG2205	protein histidine kinase activity
CE463_02610	COG0745	RESPONSE REGULATOR receiver
CE463_02620	COG1045	serine acetyltransferase
CE463_02630	COG3074	FtsZ-dependent cytokinesis
CE463_02635	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
CE463_02650	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
CE463_02700	COG1609	Transcriptional regulator
CE463_02705	COG0385	Bile acid
CE463_02710	COG1262	PFAM Formylglycine-generating sulfatase enzyme
CE463_02730	COG0583	DNA-binding transcription factor activity
CE463_02755	COG0210	DNA helicase
CE463_02795	COG2391	methyltransferase activity
CE463_02800	COG5433	transposase activity
CE463_02810	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CE463_02825	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
CE463_02830	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
CE463_02840	COG0018	arginyl-trna synthetase
CE463_02850	COG1595	DNA-templated transcription, initiation
CE463_02860	COG1968	undecaprenyl-diphosphatase activity
CE463_02865	COG0667	Aldo Keto reductase
CE463_02870	COG2017	converts alpha-aldose to the beta-anomer
CE463_02875	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
CE463_02885	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
CE463_02890	COG1609	Transcriptional regulator
CE463_02895	COG3250	beta-galactosidase activity
CE463_02910	COG4211	Belongs to the binding-protein-dependent transport system permease family
CE463_02920	COG3328	transposase activity
CE463_02950	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
CE463_02955	COG1288	antiporter activity
CE463_02965	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
CE463_02970	COG0540	Belongs to the ATCase OTCase family
CE463_02985	COG0688	phosphatidylethanolamine metabolic process
CE463_02995	COG3040	lipid binding
CE463_03005	COG1979	alcohol dehydrogenase
CE463_03010	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
CE463_03015	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
CE463_03025	COG2964	Protein conserved in bacteria
CE463_03030	COG3681	Belongs to the UPF0597 family
CE463_03040	COG0446	pyridine nucleotide-disulphide oxidoreductase
CE463_03045	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CE463_03050	COG0564	pseudouridine synthase activity
CE463_03060	COG0542	response to heat
CE463_03065	COG2502	aspartate--ammonia ligase
CE463_03070	COG1522	sequence-specific DNA binding
CE463_03080	COG5413	integral membrane protein
CE463_03085	COG0517	IMP dehydrogenase activity
CE463_03085	COG0516	GMP reductase activity
CE463_03090	COG1028	Short-chain dehydrogenase reductase Sdr
CE463_03100	COG2205	protein histidine kinase activity
CE463_03110	COG2204	response regulator
CE463_03125	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
CE463_03130	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
CE463_03145	COG0745	RESPONSE REGULATOR receiver
CE463_03150	COG2205	protein histidine kinase activity
CE463_03160	COG0243	molybdopterin cofactor binding
CE463_03165	COG3005	denitrification pathway
CE463_03170	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
CE463_03175	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
CE463_03180	COG0569	domain protein
CE463_03185	COG0812	UDP-N-acetylmuramate dehydrogenase activity
CE463_03210	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
CE463_03220	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
CE463_03225	COG0250	Participates in transcription elongation, termination and antitermination
CE463_03230	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
CE463_03235	COG0081	regulation of translation
CE463_03240	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
CE463_03245	COG0222	ribosome binding
CE463_03250	COG0085	RNA polymerase activity
CE463_03255	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
CE463_03260	COG2964	Protein conserved in bacteria
CE463_03275	COG2923	Belongs to the DsrF TusC family
CE463_03280	COG2168	tRNA wobble position uridine thiolation
CE463_03285	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
CE463_03290	COG0049	tRNA binding
CE463_03295	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
CE463_03300	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
CE463_03305	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
CE463_03365	COG3047	cAMP biosynthetic process
CE463_03395	COG3135	benzoate transporter
CE463_03400	COG1396	sequence-specific DNA binding
CE463_03440	COG2252	PERMEase
CE463_03445	COG2376	Dihydroxyacetone kinase
CE463_03450	COG1461	Dihydroxyacetone kinase
CE463_03455	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
CE463_03455	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CE463_03455	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CE463_03465	COG3284	Transcriptional regulator
CE463_03470	COG0628	permease
CE463_03475	COG0494	nUDIX hydrolase
CE463_03500	COG0753	catalase activity
CE463_03505	COG1247	-acetyltransferase
CE463_03525	COG2199	diguanylate cyclase activity
CE463_03525	COG2203	Gaf domain
CE463_03535	COG3842	ATPase activity
CE463_03545	COG1176	ABC-type spermidine putrescine transport system, permease component I
CE463_03570	COG0583	DNA-binding transcription factor activity
CE463_03580	COG1741	Belongs to the pirin family
CE463_03585	COG2259	Doxx family
CE463_03590	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
CE463_03595	COG1074	ATP-dependent DNA helicase activity
CE463_03600	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
CE463_03620	COG0346	lactoylglutathione lyase activity
CE463_03630	COG5433	transposase activity
CE463_03650	COG0347	Belongs to the P(II) protein family
CE463_03655	COG0745	RESPONSE REGULATOR receiver
CE463_03655	COG3706	GGDEF domain
CE463_03670	COG2205	protein histidine kinase activity
CE463_03675	COG3706	GGDEF domain
CE463_03685	COG1278	Cold shock
CE463_03695	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
CE463_03700	COG2197	response regulator
CE463_03750	COG2204	response regulator
CE463_03755	COG1677	Flagellar hook-basal body complex protein FliE
CE463_03765	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
CE463_03790	COG2747	anti-sigma28 factor FlgM
CE463_03800	COG1815	bacterial-type flagellum-dependent cell motility
CE463_03805	COG1558	bacterial-type flagellum-dependent cell motility
CE463_03810	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
CE463_03815	COG1749	Flagellar hook protein flgE
CE463_03820	COG4786	Flagellar basal body rod
CE463_03825	COG4786	Flagellar basal body rod
CE463_03830	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
CE463_03835	COG1706	bacterial-type flagellum-dependent cell motility
CE463_03845	COG1256	bacterial-type flagellum assembly
CE463_03845	COG4786	Flagellar basal body rod
CE463_03865	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
CE463_03875	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
CE463_03880	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
CE463_03905	COG1191	sigma factor activity
CE463_03910	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
CE463_03915	COG1360	Flagellar Motor Protein
CE463_03925	COG1388	LysM domain
CE463_03925	COG0741	lytic transglycosylase activity
CE463_03935	COG2001	Belongs to the MraZ family
CE463_03940	COG0275	rRNA processing
CE463_03945	COG3116	cell division
CE463_03950	COG0768	penicillin binding
CE463_03960	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
CE463_03965	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CE463_03970	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
CE463_03975	COG0772	Belongs to the SEDS family
CE463_03980	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
CE463_03985	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
CE463_03990	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
CE463_03995	COG0849	cell division
CE463_04000	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
CE463_04005	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
CE463_04015	COG0653	protein targeting
CE463_04025	COG0494	nUDIX hydrolase
CE463_04030	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
CE463_04035	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
CE463_04045	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
CE463_04055	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
CE463_04090	COG2186	Transcriptional regulator
CE463_04095	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
CE463_04100	COG0508	dehydrogenase complex catalyzes the overall conversion of
CE463_04105	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CE463_04110	COG5002	protein histidine kinase activity
CE463_04110	COG3447	MASE1 domain protein
CE463_04110	COG5001	Diguanylate cyclase
CE463_04120	COG0840	transmembrane signaling receptor activity
CE463_04125	COG0840	transmembrane signaling receptor activity
CE463_04135	COG1049	propionate catabolic process, 2-methylcitrate cycle
CE463_04140	COG2200	EAL domain
CE463_04145	COG1028	Short-chain dehydrogenase reductase Sdr
CE463_04150	COG0583	DNA-binding transcription factor activity
CE463_04160	COG1280	lysine exporter protein (LysE YggA)
CE463_04170	COG0523	cobalamin synthesis protein
CE463_04190	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
CE463_04195	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
CE463_04335	COG0835	chemotaxis
CE463_04335	COG0784	Response regulator, receiver
CE463_04340	COG1028	Short-chain dehydrogenase reductase Sdr
CE463_04345	COG1444	tRNA N-acetyltransferase activity
CE463_04370	COG1803	Methylglyoxal synthase
CE463_04385	COG0252	asparaginase activity
CE463_04395	COG1609	Transcriptional regulator
CE463_04405	COG1940	carbohydrate kinase activity
CE463_04410	COG1447	Phosphotransferase system cellobiose-specific component IIA
CE463_04415	COG2723	6-phospho-beta-galactosidase activity
CE463_04425	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CE463_04430	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CE463_04445	COG1263	PTS System
CE463_04445	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CE463_04450	COG0366	Alpha amylase catalytic
CE463_04455	COG0110	maltose O-acetyltransferase activity
CE463_04465	COG1757	Na H antiporter
CE463_04500	COG0297	glycogen (starch) synthase activity
CE463_04505	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
CE463_04510	COG2813	Specifically methylates the guanine in position
CE463_04515	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CE463_04530	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CE463_04540	COG2995	paraquat-inducible protein a
CE463_04545	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
CE463_04545	COG3008	intermembrane lipid transfer
CE463_04550	COG3009	Protein conserved in bacteria
CE463_04565	COG3240	lipase activity
CE463_04570	COG3111	PFAM Bacterial OB fold (BOF) protein
CE463_04580	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
CE463_04585	COG1194	a g-specific adenine glycosylase
CE463_04595	COG3267	Type II secretory pathway component ExeA
CE463_04595	COG3409	Peptidoglycan-binding domain 1 protein
CE463_04600	COG0617	tRNA 3'-terminal CCA addition
CE463_04605	COG0306	phosphate transporter
CE463_04610	COG1392	Phosphate transport regulator
CE463_04625	COG1560	Kdo2-lipid A biosynthetic process
CE463_04630	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
CE463_04630	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
CE463_04635	COG1538	Outer membrane efflux protein
CE463_04640	COG0494	nUDIX hydrolase
CE463_04645	COG3151	Protein conserved in bacteria
CE463_04655	COG3150	esterase
CE463_04660	COG1051	belongs to the nudix hydrolase family
CE463_04670	COG0187	DNA topoisomerase II activity
CE463_04740	COG2259	Doxx family
CE463_04745	COG3118	belongs to the thioredoxin family
CE463_04765	COG0204	Acyl-transferase
CE463_04785	COG2827	Endonuclease containing a URI domain
CE463_04800	COG1573	uracil-dna glycosylase
CE463_04810	COG0583	DNA-binding transcription factor activity
CE463_04815	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CE463_04820	COG1121	(ABC) transporter
CE463_04825	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
CE463_04845	COG0739	heme binding
CE463_04855	COG3068	Protein conserved in bacteria
CE463_04875	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
CE463_04895	COG0798	PFAM Bile acid sodium symporter
CE463_04900	COG1393	Belongs to the ArsC family
CE463_04910	COG2072	flavoprotein involved in K transport
CE463_04920	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
CE463_04930	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
CE463_04935	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
CE463_04945	COG0137	argininosuccinate synthase activity
CE463_04950	COG0165	Argininosuccinate lyase
CE463_04955	COG0583	DNA-binding transcription factor activity
CE463_04965	COG1942	4-Oxalocrotonate Tautomerase
CE463_04995	COG0110	maltose O-acetyltransferase activity
CE463_05000	COG3174	membrane
CE463_05005	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
CE463_05015	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
CE463_05025	COG4208	sulfate ABC transporter
CE463_05030	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
CE463_05035	COG0583	DNA-binding transcription factor activity
CE463_05040	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
CE463_05045	COG0765	amino acid transport
CE463_05055	COG1126	abc transporter atp-binding protein
CE463_05060	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CE463_05065	COG3397	chitin binding
CE463_05105	COG0726	polysaccharide deacetylase
CE463_05105	COG1649	PFAM Uncharacterised BCR, COG1649
CE463_05110	COG1215	transferase activity, transferring glycosyl groups
CE463_05155	COG1328	CTP reductase activity
CE463_05160	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
CE463_05180	COG1448	Aminotransferase
CE463_05220	COG0513	Belongs to the DEAD box helicase family
CE463_05235	COG3568	Endonuclease Exonuclease Phosphatase
CE463_05240	COG0840	transmembrane signaling receptor activity
CE463_05255	COG3112	Uncharacterised protein family (UPF0231)
CE463_05260	COG3835	regulator
CE463_05265	COG2610	gluconate transmembrane transporter activity
CE463_05270	COG1929	Belongs to the glycerate kinase type-1 family
CE463_05290	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
CE463_05305	COG0347	Belongs to the P(II) protein family
CE463_05310	COG1840	ABC-type Fe3 transport system, periplasmic component
CE463_05320	COG3842	ATPase activity
CE463_05325	COG2837	iron assimilation
CE463_05330	COG1438	arginine binding
CE463_05335	COG1126	abc transporter atp-binding protein
CE463_05340	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CE463_05345	COG4215	(ABC) transporter
CE463_05350	COG4160	amino acid transport
CE463_05355	COG0039	L-malate dehydrogenase activity
CE463_05360	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
CE463_05365	COG1017	nitric oxide dioxygenase activity
CE463_05365	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CE463_05370	COG1959	2 iron, 2 sulfur cluster binding
CE463_05375	COG4536	flavin adenine dinucleotide binding
CE463_05380	COG4137	Cytochrome C assembly protein
CE463_05385	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
CE463_05390	COG0228	four-way junction DNA binding
CE463_05395	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
CE463_05400	COG0336	Belongs to the RNA methyltransferase TrmD family
CE463_05405	COG0335	large ribosomal subunit rRNA binding
CE463_05415	COG3066	DNA modification
CE463_05420	COG1051	belongs to the nudix hydrolase family
CE463_05430	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
CE463_05435	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
CE463_05440	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
CE463_05450	COG0583	DNA-binding transcription factor activity
CE463_05455	COG0640	Transcriptional regulator
CE463_05460	COG0268	Binds directly to 16S ribosomal RNA
CE463_05465	COG0728	peptidoglycan biosynthetic process
CE463_05470	COG0196	riboflavin kinase activity
CE463_05475	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
CE463_05480	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
CE463_05485	COG1047	Peptidyl-prolyl cis-trans
CE463_05490	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
CE463_05495	COG4968	Prepilin-type N-terminal cleavage methylation domain
CE463_05530	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CE463_05530	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
CE463_05545	COG1854	S-ribosylhomocysteine lyase activity
CE463_05550	COG3706	GGDEF domain
CE463_05555	COG0557	exoribonuclease II activity
CE463_05560	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CE463_05570	COG2153	protein acetylation
CE463_05590	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
CE463_05595	COG1914	H( )-stimulated, divalent metal cation uptake system
CE463_05600	COG0360	Binds together with S18 to 16S ribosomal RNA
CE463_05605	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
CE463_05610	COG0359	binds to the 23S rRNA
CE463_05640	COG1064	alcohol dehydrogenase
CE463_05645	COG1238	metal cluster binding
CE463_05650	COG0612	Peptidase, M16
CE463_05655	COG2918	glutathione biosynthetic process
CE463_05665	COG1022	Amp-dependent synthetase and ligase
CE463_05675	COG0456	acetyltransferase
CE463_05685	COG0714	Associated with various cellular activities
CE463_05710	COG0745	RESPONSE REGULATOR receiver
CE463_05710	COG3706	GGDEF domain
CE463_05715	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
CE463_05725	COG1902	pentaerythritol trinitrate reductase activity
CE463_05735	COG0442	prolyl-tRNA aminoacylation
CE463_05745	COG0632	four-way junction helicase activity
CE463_05750	COG2255	four-way junction helicase activity
CE463_05755	COG1271	oxidase subunit
CE463_05760	COG1294	oxidase, subunit
CE463_05765	COG4890	Cyd operon protein YbgT
CE463_05770	COG3790	cyd operon protein YbgE
CE463_05775	COG0824	Thioesterase
CE463_05780	COG0811	peptide transport
CE463_05795	COG0823	Involved in the tonB-independent uptake of proteins
CE463_05800	COG2885	chlorophyll binding
CE463_05805	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
CE463_05870	COG0840	transmembrane signaling receptor activity
CE463_05875	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
CE463_05880	COG0676	glucose-6-phosphate 1-epimerase activity
CE463_05885	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
CE463_05890	COG1640	4-alpha-glucanotransferase
CE463_05895	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
CE463_05915	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CE463_05920	COG4991	sh3 domain protein
CE463_05925	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
CE463_05925	COG0506	proline dehydrogenase activity
CE463_05925	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
CE463_05935	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
CE463_05940	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
CE463_05945	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
CE463_05950	COG0163	prenyltransferase activity
CE463_05965	COG1131	(ABC) transporter
CE463_05970	COG0842	Transport permease protein
CE463_05980	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
CE463_05985	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
CE463_05990	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
CE463_05995	COG0617	tRNA 3'-terminal CCA addition
CE463_06000	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CE463_06005	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
CE463_06010	COG1489	DNA binding
CE463_06020	COG1643	Atp-dependent helicase
CE463_06025	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CE463_06030	COG0346	lactoylglutathione lyase activity
CE463_06040	COG2076	Multidrug Resistance protein
CE463_06045	COG0583	DNA-binding transcription factor activity
CE463_06050	COG0784	Response regulator, receiver
CE463_06050	COG3437	response regulator, receiver
CE463_06060	COG0671	phosphoesterase, PA-phosphatase related
CE463_06075	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
CE463_06080	COG0038	chloride channel
CE463_06090	COG0316	Belongs to the HesB IscA family
CE463_06120	COG2816	NAD+ diphosphatase activity
CE463_06125	COG2205	protein histidine kinase activity
CE463_06130	COG0745	RESPONSE REGULATOR receiver
CE463_06135	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CE463_06150	COG1505	serine-type exopeptidase activity
CE463_06155	COG2982	Protein involved in outer membrane biogenesis
CE463_06165	COG1028	Short-chain dehydrogenase reductase Sdr
CE463_06200	COG1349	DNA-binding transcription factor activity
CE463_06205	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
CE463_06225	COG2130	NADP-dependent
CE463_06230	COG1764	response to oxidative stress
CE463_06235	COG1846	Transcriptional regulator
CE463_06265	COG0561	phosphatase activity
CE463_06280	COG0733	neurotransmitter:sodium symporter activity
CE463_06290	COG0733	neurotransmitter:sodium symporter activity
CE463_06315	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CE463_06330	COG1794	racemase activity, acting on amino acids and derivatives
CE463_06340	COG2731	YhcH YjgK YiaL family protein
CE463_06350	COG0668	transmembrane transport
CE463_06355	COG1376	ErfK ybiS ycfS ynhG family protein
CE463_06360	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CE463_06395	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
CE463_06405	COG0488	(ABC) transporter
CE463_06410	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
CE463_06410	COG0517	IMP dehydrogenase activity
CE463_06415	COG1585	Membrane protein implicated in regulation of membrane protease activity
CE463_06420	COG0330	HflC and HflK could
CE463_06425	COG1648	precorrin-2 dehydrogenase activity
CE463_06425	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
CE463_06430	COG0175	sulfate reduction
CE463_06435	COG2895	sulfate adenylyltransferase (ATP) activity
CE463_06440	COG0471	metal ion transport
CE463_06440	COG3273	potassium ion transport
CE463_06445	COG0529	Catalyzes the synthesis of activated sulfate
CE463_06450	COG5433	transposase activity
CE463_06515	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
CE463_06540	COG1940	carbohydrate kinase activity
CE463_06545	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
CE463_06550	COG0126	phosphoglycerate kinase activity
CE463_06555	COG0191	fructose-bisphosphate aldolase activity
CE463_06560	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CE463_06610	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
CE463_06615	COG1595	DNA-templated transcription, initiation
CE463_06620	COG3073	An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E
CE463_06635	COG0481	GTPase activity
CE463_06640	COG0681	Belongs to the peptidase S26 family
CE463_06645	COG0571	ribonuclease III activity
CE463_06655	COG1381	Involved in DNA repair and RecF pathway recombination
CE463_06660	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
CE463_06665	COG3023	N-Acetylmuramoyl-L-alanine amidase
CE463_06670	COG4807	Protein conserved in bacteria
CE463_06680	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
CE463_06685	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CE463_06690	COG3956	TIGRFAM MazG family protein
CE463_06695	COG0504	CTP synthase activity
CE463_06700	COG0148	phosphopyruvate hydratase activity
CE463_06705	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
CE463_06710	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
CE463_06720	COG0585	pseudouridine synthase activity
CE463_06725	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
CE463_06730	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
CE463_06735	COG1238	metal cluster binding
CE463_06740	COG1388	LysM domain
CE463_06740	COG4942	peptidase
CE463_06750	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
CE463_06755	COG0828	Belongs to the bacterial ribosomal protein bS21 family
CE463_06760	COG1610	YqeY-like protein
CE463_06765	COG0358	DNA primase activity
CE463_06770	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CE463_06810	COG0151	Belongs to the GarS family
CE463_06815	COG0138	bifunctional purine biosynthesis protein purh
CE463_06825	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
CE463_06830	COG3036	rescue of stalled ribosome
CE463_06835	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CE463_06840	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
CE463_06850	COG0673	inositol 2-dehydrogenase activity
CE463_06860	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CE463_06865	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CE463_06870	COG3227	Zinc metalloprotease (Elastase)
CE463_06880	COG0477	Major facilitator Superfamily
CE463_06890	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
CE463_06895	COG1027	Aspartate ammonia-lyase
CE463_06900	COG3030	protein affecting phage T7 exclusion by the F plasmid
CE463_06910	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
CE463_06915	COG0459	protein refolding
CE463_06925	COG5001	Diguanylate cyclase
CE463_06925	COG3300	MHYT domain
CE463_06935	COG0564	pseudouridine synthase activity
CE463_06940	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
CE463_06970	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CE463_06980	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
CE463_06985	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
CE463_06990	COG1178	ABC-type Fe3 transport system permease component
CE463_06995	COG4143	(ABC) transporter
CE463_07010	COG0066	3-isopropylmalate dehydratase activity
CE463_07015	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
CE463_07020	COG0473	3-isopropylmalate dehydrogenase activity
CE463_07025	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CE463_07035	COG0671	phosphoesterase, PA-phosphatase related
CE463_07050	COG0028	Belongs to the TPP enzyme family
CE463_07055	COG0440	acetolactate synthase activity
CE463_07060	COG0280	phosphate acetyltransferase
CE463_07060	COG0857	belongs to the CobB CobQ family
CE463_07065	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
CE463_07070	COG3092	negative regulation of chromosome organization
CE463_07075	COG3013	Belongs to the UPF0304 family
CE463_07080	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
CE463_07085	COG2716	regulation of RNA biosynthetic process
CE463_07095	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
CE463_07100	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
CE463_07135	COG5002	protein histidine kinase activity
CE463_07135	COG2198	Histidine kinase
CE463_07135	COG0784	Response regulator, receiver
CE463_07160	COG0840	transmembrane signaling receptor activity
CE463_07170	COG1464	Belongs to the NlpA lipoprotein family
CE463_07175	COG2011	ABC-type metal ion transport system permease component
CE463_07180	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
CE463_07200	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
CE463_07200	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
CE463_07205	COG0802	atpase or kinase
CE463_07215	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
CE463_07220	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
CE463_07225	COG1923	regulation of RNA biosynthetic process
CE463_07230	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
CE463_07235	COG0330	HflC and HflK could
CE463_07240	COG0330	HflC and HflK could
CE463_07245	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
CE463_07250	COG0142	geranyltranstransferase activity
CE463_07255	COG0261	This protein binds to 23S rRNA in the presence of protein L20
CE463_07260	COG0211	Belongs to the bacterial ribosomal protein bL27 family
CE463_07265	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
CE463_07275	COG0318	PFAM AMP-dependent synthetase and ligase
CE463_07295	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CE463_07310	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
CE463_07320	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
CE463_07325	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
CE463_07335	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
CE463_07340	COG3178	'Phosphotransferase
CE463_07345	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
CE463_07350	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
CE463_07355	COG2252	PERMEase
CE463_07365	COG0488	(ABC) transporter
CE463_07390	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CE463_07400	COG3721	Heme iron utilization protein
CE463_07405	COG0748	coenzyme F420 binding
CE463_07425	COG4771	TonB-dependent receptor
CE463_07430	COG2814	Major facilitator Superfamily
CE463_07440	COG3655	Transcriptional regulator
CE463_07475	COG3397	chitin binding
CE463_07485	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CE463_07490	COG1765	OsmC-like protein
CE463_07505	COG3954	Phosphoribulokinase
CE463_07515	COG2076	Multidrug Resistance protein
CE463_07520	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
CE463_07525	COG0726	polysaccharide deacetylase
CE463_07535	COG0463	Glycosyl transferase, family 2
CE463_07540	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
CE463_07550	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
CE463_07560	COG3089	Belongs to the UPF0270 family
CE463_07565	COG3706	GGDEF domain
CE463_07565	COG4251	negative regulation of phosphorylation
CE463_07565	COG2203	Gaf domain
CE463_07565	COG5001	Diguanylate cyclase
CE463_07570	COG0429	hydrolase of the alpha beta-hydrolase fold
CE463_07575	COG0835	chemotaxis
CE463_07575	COG0784	Response regulator, receiver
CE463_07585	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
CE463_07590	COG1047	Peptidyl-prolyl cis-trans
CE463_07595	COG2900	Belongs to the SlyX family
CE463_07605	COG0545	Peptidyl-prolyl cis-trans isomerase
CE463_07610	COG2204	response regulator
CE463_07630	COG0737	Belongs to the 5'-nucleotidase family
CE463_07635	COG2200	EAL domain
CE463_07650	COG0305	Participates in initiation and elongation during chromosome replication
CE463_07655	COG0305	Participates in initiation and elongation during chromosome replication
CE463_07660	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
CE463_07665	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
CE463_07675	COG2203	Gaf domain
CE463_07675	COG2200	EAL domain
CE463_07675	COG2199	diguanylate cyclase activity
CE463_07720	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
CE463_07725	COG2201	protein-glutamate methylesterase activity
CE463_07755	COG2916	Histone family protein nucleoid-structuring protein H-NS
CE463_07760	COG3328	transposase activity
CE463_07770	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
CE463_07775	COG2375	cellular response to nickel ion
CE463_07780	COG1538	Outer membrane efflux protein
CE463_07785	COG0577	efflux transmembrane transporter activity
CE463_07785	COG1136	(ABC) transporter
CE463_07790	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CE463_07800	COG1227	inorganic diphosphatase activity
CE463_07805	COG0497	DNA recombination
CE463_07810	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
CE463_07815	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
CE463_07820	COG0443	Heat shock 70 kDa protein
CE463_07825	COG0484	heat shock protein binding
CE463_07855	COG1285	pathogenesis
CE463_07870	COG0640	Transcriptional regulator
CE463_07905	COG0095	Lipoate-protein ligase
CE463_07945	COG0708	Exodeoxyribonuclease III
CE463_08005	COG2814	Major facilitator Superfamily
CE463_08010	COG0109	protoheme IX farnesyltransferase activity
CE463_08020	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
CE463_08025	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
CE463_08060	COG1609	Transcriptional regulator
CE463_08065	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CE463_08065	COG1263	PTS System
CE463_08085	COG5433	transposase activity
CE463_08100	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CE463_08115	COG2207	Transcriptional regulator
CE463_08120	COG0538	isocitrate dehydrogenase activity
CE463_08165	COG0582	viral genome integration into host DNA
CE463_08175	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
CE463_08180	COG2867	negative regulation of translational initiation
CE463_08190	COG0702	epimerase
CE463_08195	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CE463_08225	COG4964	Belongs to the GSP D family
CE463_08235	COG2894	cell division
CE463_08275	COG1454	alcohol dehydrogenase
CE463_08290	COG1957	nucleoside hydrolase
CE463_08310	COG0840	transmembrane signaling receptor activity
CE463_08315	COG1280	lysine exporter protein (LysE YggA)
CE463_08325	COG5433	transposase activity
CE463_08330	COG4580	involved in the transport of maltose and maltodextrins
CE463_08340	COG1263	PTS System
CE463_08340	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CE463_08350	COG2171	N-acyltransferase activity
CE463_08360	COG0024	Methionine aminopeptidase
CE463_08365	COG0052	Belongs to the universal ribosomal protein uS2 family
CE463_08370	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
CE463_08375	COG0528	UMP kinase activity
CE463_08380	COG0233	cytoplasmic translational termination
CE463_08385	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
CE463_08390	COG0575	Belongs to the CDS family
CE463_08395	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
CE463_08400	COG0750	zinc metalloprotease
CE463_08415	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CE463_08420	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
CE463_08425	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CE463_08430	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CE463_08435	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
CE463_08445	COG0825	malonyl-CoA metabolic process
CE463_08450	COG3710	Transcriptional regulator
CE463_08455	COG0531	amino acid
CE463_08460	COG1982	Orn Lys Arg decarboxylase major
CE463_08465	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
CE463_08480	COG0814	amino acid
CE463_08485	COG0531	amino acid
CE463_08495	COG0488	(ABC) transporter
CE463_08505	COG3590	peptidase
CE463_08510	COG0037	tRNA processing
CE463_08515	COG3706	GGDEF domain
CE463_08550	COG0366	Alpha amylase catalytic
CE463_08560	COG1881	PFAM PEBP family protein
CE463_08570	COG0583	DNA-binding transcription factor activity
CE463_08580	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
CE463_08590	COG0583	DNA-binding transcription factor activity
CE463_08595	COG1028	Short-chain dehydrogenase reductase Sdr
CE463_08600	COG0616	signal peptide processing
CE463_08605	COG3724	N-succinylarginine dihydrolase activity
CE463_08610	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
CE463_08620	COG0840	transmembrane signaling receptor activity
CE463_08630	COG2971	BadF BadG BcrA BcrD
CE463_08640	COG4608	Belongs to the ABC transporter superfamily
CE463_08645	COG0444	Belongs to the ABC transporter superfamily
CE463_08650	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CE463_08700	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
CE463_08705	COG1289	transmembrane transporter activity
CE463_08710	COG0303	'Molybdopterin
CE463_08715	COG0746	molybdenum cofactor guanylyltransferase activity
CE463_08725	COG4662	Binding-protein-dependent transport system inner membrane component
CE463_08740	COG3852	Histidine kinase
CE463_08750	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
CE463_08765	COG5433	transposase activity
CE463_08795	COG5433	transposase activity
CE463_08825	COG3383	formate dehydrogenase (NAD+) activity
CE463_08830	COG0437	4 iron, 4 sulfur cluster binding
CE463_08845	COG0281	malic enzyme
CE463_08855	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CE463_08875	COG0281	malic enzyme
CE463_08880	COG3290	protein histidine kinase activity
CE463_08895	COG0667	Aldo Keto reductase
CE463_08905	COG0697	spore germination
CE463_08925	COG2267	carboxylic ester hydrolase activity
CE463_08930	COG1942	4-Oxalocrotonate Tautomerase
CE463_08935	COG1012	belongs to the aldehyde dehydrogenase family
CE463_08940	COG3284	Transcriptional regulator
CE463_08945	COG3706	GGDEF domain
CE463_08950	COG0346	lactoylglutathione lyase activity
CE463_08955	COG0745	RESPONSE REGULATOR receiver
CE463_08960	COG5002	protein histidine kinase activity
CE463_08970	COG4783	chaperone-mediated protein folding
CE463_08980	COG1940	carbohydrate kinase activity
CE463_08985	COG3142	Participates in the control of copper homeostasis
CE463_08990	COG0545	Peptidyl-prolyl cis-trans isomerase
CE463_08995	COG1131	(ABC) transporter
CE463_09015	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
CE463_09035	COG0019	diaminopimelate decarboxylase activity
CE463_09040	COG1115	amino acid carrier protein
CE463_09045	COG0095	Lipoate-protein ligase
CE463_09050	COG2233	PERMEase
CE463_09055	COG3706	GGDEF domain
CE463_09055	COG0745	RESPONSE REGULATOR receiver
CE463_09065	COG0534	Mate efflux family protein
CE463_09070	COG2207	Transcriptional regulator
CE463_09075	COG0281	malic enzyme
CE463_09080	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
CE463_09080	COG2885	chlorophyll binding
CE463_09110	COG0733	neurotransmitter:sodium symporter activity
CE463_09115	COG1752	Esterase of the alpha-beta hydrolase superfamily
CE463_09120	COG3706	GGDEF domain
CE463_09125	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CE463_09140	COG1032	radical SAM domain protein
CE463_09155	COG5433	transposase activity
CE463_09170	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
CE463_09175	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
CE463_09180	COG0739	heme binding
CE463_09180	COG0741	lytic transglycosylase activity
CE463_09180	COG1196	nuclear chromosome segregation
CE463_09185	COG0366	Alpha amylase catalytic
CE463_09205	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CE463_09215	COG0788	formyltetrahydrofolate deformylase activity
CE463_09220	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CE463_09230	COG3118	belongs to the thioredoxin family
CE463_09235	COG2091	lysine biosynthetic process via aminoadipic acid
CE463_09240	COG0791	NLP P60 protein
CE463_09245	COG3129	Specifically methylates the adenine in position 1618 of 23S rRNA
CE463_09260	COG1388	LysM domain
CE463_09260	COG1376	ErfK ybiS ycfS ynhG family protein
CE463_09310	COG1960	acyl-CoA dehydrogenase activity
CE463_09315	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CE463_09325	COG0469	pyruvate kinase activity
CE463_09330	COG1737	Transcriptional regulator
CE463_09355	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CE463_09375	COG1342	Belongs to the UPF0251 family
CE463_09425	COG1987	bacterial-type flagellum assembly
CE463_09430	COG1684	flagellar biosynthetic protein fliR
CE463_09440	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
CE463_09450	COG0455	bacterial-type flagellum organization
CE463_09465	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
CE463_09475	COG0450	alkyl hydroperoxide reductase
CE463_09495	COG0500	methyltransferase
CE463_09500	COG4106	trans-aconitate 2-methyltransferase activity
CE463_09520	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
CE463_09525	COG0217	transcriptional regulatory protein
CE463_09585	COG1846	Transcriptional regulator
CE463_09585	COG1940	carbohydrate kinase activity
CE463_09590	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
CE463_09595	COG0363	glucosamine-6-phosphate deaminase activity
CE463_09615	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CE463_09620	COG0735	belongs to the Fur family
CE463_09630	COG0716	FMN binding
CE463_09645	COG0596	Alpha beta hydrolase
CE463_09650	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
CE463_09655	COG0033	Phosphoglucomutase
CE463_09665	COG1846	Transcriptional regulator
CE463_09670	COG2951	lytic endotransglycosylase activity
CE463_09675	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
CE463_09680	COG4136	ATPase activity
CE463_09685	COG4135	transport system, permease component
CE463_09690	COG4134	Bacterial extracellular solute-binding protein
CE463_09700	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CE463_09710	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CE463_09715	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CE463_09730	COG0729	surface antigen
CE463_09735	COG2911	Protein conserved in bacteria
CE463_09750	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
CE463_09775	COG1607	acyl-coa hydrolase
CE463_09785	COG3021	interspecies interaction between organisms
CE463_09790	COG1388	LysM domain
CE463_09790	COG0741	lytic transglycosylase activity
CE463_09795	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CE463_09800	COG2226	methyltransferase
CE463_09805	COG0328	RNA-DNA hybrid ribonuclease activity
CE463_09810	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CE463_09820	COG3437	response regulator, receiver
CE463_09820	COG0784	Response regulator, receiver
CE463_09825	COG1960	acyl-CoA dehydrogenase activity
CE463_09830	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
CE463_09835	COG0121	glutamine amidotransferase
CE463_09855	COG0784	Response regulator, receiver
CE463_09855	COG2205	protein histidine kinase activity
CE463_09865	COG2197	response regulator
CE463_09870	COG3850	Histidine kinase
CE463_09875	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
CE463_09880	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
CE463_09890	COG0243	molybdopterin cofactor binding
CE463_09895	COG0437	4 iron, 4 sulfur cluster binding
CE463_09900	COG0348	domain, Protein
CE463_09910	COG3005	denitrification pathway
CE463_09915	COG0521	Mo-molybdopterin cofactor biosynthetic process
CE463_09920	COG0315	cyclic pyranopterin monophosphate synthase activity
CE463_09925	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
CE463_09930	COG0314	molybdopterin synthase activity
CE463_09945	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
CE463_09950	COG0596	Alpha beta hydrolase
CE463_09975	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
CE463_09985	COG0302	gtp cyclohydrolase
CE463_09990	COG0840	transmembrane signaling receptor activity
CE463_09995	COG2759	Belongs to the formate--tetrahydrofolate ligase family
CE463_10005	COG0583	DNA-binding transcription factor activity
CE463_10010	COG2353	YceI-like domain
CE463_10035	COG2195	Cleaves the N-terminal amino acid of tripeptides
CE463_10045	COG1166	arginine decarboxylase activity
CE463_10060	COG0346	lactoylglutathione lyase activity
CE463_10070	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
CE463_10075	COG1187	pseudouridine synthase activity
CE463_10080	COG2807	transmembrane transport
CE463_10090	COG0583	DNA-binding transcription factor activity
CE463_10110	COG2979	Protein of unknown function (DUF533)
CE463_10115	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CE463_10145	COG2814	Major facilitator Superfamily
CE463_10150	COG0656	L-ascorbic acid biosynthetic process
CE463_10155	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
CE463_10180	COG0583	DNA-binding transcription factor activity
CE463_10185	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
CE463_10190	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
CE463_10195	COG2271	Major facilitator Superfamily
CE463_10200	COG1349	DNA-binding transcription factor activity
CE463_10210	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
CE463_10215	COG0584	glycerophosphoryl diester phosphodiesterase
CE463_10220	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
CE463_10225	COG1605	Chorismate mutase
CE463_10225	COG0287	Prephenate dehydrogenase
CE463_10230	COG0583	DNA-binding transcription factor activity
CE463_10235	COG3085	chromosome segregation
CE463_10240	COG4574	serine-type endopeptidase inhibitor activity
CE463_10260	COG1770	oligopeptidase
CE463_10280	COG3083	sulfuric ester hydrolase activity
CE463_10285	COG3082	Protein of unknown function (DUF1414)
CE463_10290	COG3081	Nucleoid-associated protein
CE463_10295	COG2182	Extracellular solute-binding protein
CE463_10300	COG1175	transmembrane transport
CE463_10310	COG3842	ATPase activity
CE463_10325	COG0628	permease
CE463_10330	COG0425	Belongs to the sulfur carrier protein TusA family
CE463_10335	COG4783	chaperone-mediated protein folding
CE463_10345	COG1393	Belongs to the ArsC family
CE463_10360	COG2431	L-lysine efflux transmembrane transporter activity
CE463_10375	COG4215	(ABC) transporter
CE463_10395	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
CE463_10405	COG0446	pyridine nucleotide-disulphide oxidoreductase
CE463_10410	COG2373	Large extracellular alpha-helical protein
CE463_10415	COG4953	penicillin-binding protein 1C
CE463_10425	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CE463_10425	COG0301	tRNA thio-modification
CE463_10440	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
CE463_10470	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CE463_10480	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
CE463_10500	COG0483	inositol monophosphate 1-phosphatase activity
CE463_10510	COG0625	glutathione transferase activity
CE463_10520	COG0601	transmembrane transport
CE463_10525	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CE463_10530	COG0444	Belongs to the ABC transporter superfamily
CE463_10535	COG2814	Major facilitator Superfamily
CE463_10540	COG0583	DNA-binding transcription factor activity
CE463_10545	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
CE463_10550	COG0243	molybdopterin cofactor binding
CE463_10570	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CE463_10575	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CE463_10580	COG0404	The glycine cleavage system catalyzes the degradation of glycine
CE463_10585	COG0509	glycine decarboxylation via glycine cleavage system
CE463_10590	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
CE463_10590	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
CE463_10605	COG3634	alkyl hydroperoxide reductase activity
CE463_10610	COG0450	alkyl hydroperoxide reductase
CE463_10615	COG0517	IMP dehydrogenase activity
CE463_10620	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
CE463_10625	COG0343	queuine tRNA-ribosyltransferase activity
CE463_10630	COG1862	Preprotein translocase
CE463_10635	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CE463_10640	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CE463_10645	COG2897	thiosulfate sulfurtransferase activity
CE463_10680	COG1959	2 iron, 2 sulfur cluster binding
CE463_10685	COG1104	cysteine desulfurase activity
CE463_10690	COG0822	iron-sulfur transferase activity
CE463_10700	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
CE463_10705	COG0443	Heat shock 70 kDa protein
CE463_10710	COG0633	Ferredoxin
CE463_10720	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
CE463_10725	COG0105	UTP biosynthetic process
CE463_10730	COG0820	rRNA (adenine-C2-)-methyltransferase activity
CE463_10740	COG1426	Protein conserved in bacteria
CE463_10745	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
CE463_10750	COG0124	histidyl-tRNA synthetase
CE463_10755	COG2976	Protein conserved in bacteria
CE463_10760	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CE463_10765	COG1160	GTP binding
CE463_10770	COG1645	bacterial-type flagellum-dependent swarming motility
CE463_10775	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
CE463_10780	COG0047	phosphoribosylformylglycinamidine synthase activity
CE463_10780	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CE463_10790	COG2354	Protein conserved in bacteria
CE463_10805	COG5433	transposase activity
CE463_10830	COG1242	4 iron, 4 sulfur cluster binding
CE463_10900	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
CE463_10905	COG1288	antiporter activity
CE463_10910	COG0436	Aminotransferase
CE463_10920	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
CE463_10925	COG2027	D-alanyl-D-alanine carboxypeptidase
CE463_10930	COG1061	Type III restriction enzyme res subunit
CE463_10935	COG1566	PFAM secretion protein HlyD family protein
CE463_10945	COG1966	Carbon starvation protein
CE463_10950	COG3279	Response regulator of the LytR AlgR family
CE463_10955	COG3275	phosphorelay sensor kinase activity
CE463_10975	COG1454	alcohol dehydrogenase
CE463_10975	COG1012	belongs to the aldehyde dehydrogenase family
CE463_10985	COG2095	MarC family integral membrane protein
CE463_10995	COG0601	transmembrane transport
CE463_11000	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CE463_11005	COG0444	Belongs to the ABC transporter superfamily
CE463_11020	COG0861	Integral membrane protein TerC family
CE463_11025	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
CE463_11035	COG1301	dicarboxylic acid transport
CE463_11050	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
CE463_11065	COG0537	adenosine 5'-monophosphoramidase activity
CE463_11100	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CE463_11105	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CE463_11120	COG5433	transposase activity
CE463_11135	COG1007	ATP synthesis coupled electron transport
CE463_11140	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CE463_11150	COG0713	ATP synthesis coupled electron transport
CE463_11155	COG0839	Belongs to the complex I subunit 6 family
CE463_11160	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CE463_11165	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
CE463_11170	COG1034	ATP synthesis coupled electron transport
CE463_11185	COG0649	NAD binding
CE463_11185	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CE463_11190	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CE463_11195	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CE463_11200	COG1360	Flagellar Motor Protein
CE463_11220	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
CE463_11235	COG4597	amino acid ABC transporter
CE463_11240	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CE463_11245	COG0765	amino acid transport
CE463_11250	COG1126	abc transporter atp-binding protein
CE463_11260	COG0724	RNA recognition motif
CE463_11265	COG4989	oxidoreductase activity
CE463_11295	COG0583	DNA-binding transcription factor activity
CE463_11310	COG3300	MHYT domain
CE463_11310	COG5001	Diguanylate cyclase
CE463_11330	COG2814	Major facilitator Superfamily
CE463_11345	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CE463_11350	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
CE463_11355	COG0539	negative regulation of cytoplasmic translation
CE463_11360	COG0776	regulation of translation
CE463_11370	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
CE463_11375	COG0284	orotidine-5'-phosphate decarboxylase activity
CE463_11390	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
CE463_11395	COG0602	queuosine metabolic process
CE463_11400	COG3530	Putative quorum-sensing-regulated virulence factor
CE463_11405	COG2096	Adenosyltransferase
CE463_11410	COG2916	Histone family protein nucleoid-structuring protein H-NS
CE463_11425	COG1757	Na H antiporter
CE463_11430	COG1435	thymidine kinase activity
CE463_11455	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
CE463_11470	COG5433	transposase activity
CE463_11480	COG0437	4 iron, 4 sulfur cluster binding
CE463_11485	COG5557	Pfam Polysulphide reductase, NrfD
CE463_11490	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
CE463_11495	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
CE463_11500	COG1773	rubredoxin
CE463_11510	COG0601	transmembrane transport
CE463_11515	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CE463_11530	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
CE463_11535	COG0375	protein maturation
CE463_11540	COG0309	Hydrogenase expression formation protein (HypE)
CE463_11550	COG0298	carbon dioxide binding
CE463_11555	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
CE463_11565	COG1921	L-seryl-tRNASec selenium transferase activity
CE463_11580	COG3260	NADH ubiquinone oxidoreductase 20
CE463_11585	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CE463_11590	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
CE463_11590	COG3261	NADH dehydrogenase
CE463_11595	COG0650	Formate hydrogenlyase subunit 4
CE463_11600	COG0651	ATP synthesis coupled electron transport
CE463_11605	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
CE463_11655	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
CE463_11660	COG0326	Molecular chaperone. Has ATPase activity
CE463_11670	COG0563	adenylate kinase activity
CE463_11675	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
CE463_11680	COG3788	relative of glutathione S-transferase, MAPEG superfamily
CE463_11685	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CE463_11690	COG0840	transmembrane signaling receptor activity
CE463_11745	COG1021	2,3-dihydroxybenzoate-AMP ligase
CE463_11750	COG3433	isochorismatase activity
CE463_11750	COG1535	isochorismatase
CE463_11755	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CE463_11760	COG1028	Short-chain dehydrogenase reductase Sdr
CE463_11775	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CE463_11780	COG2977	Belongs to the P-Pant transferase superfamily
CE463_11785	COG1120	ATPase activity
CE463_11790	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CE463_11795	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CE463_11800	COG4771	TonB-dependent receptor
CE463_11820	COG0598	Magnesium transport protein CorA
CE463_11840	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
CE463_11845	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
CE463_11850	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
CE463_11865	COG1570	exodeoxyribonuclease VII activity
CE463_11885	COG5433	transposase activity
CE463_11910	COG0517	IMP dehydrogenase activity
CE463_11910	COG0516	GMP reductase activity
CE463_11915	COG0519	Catalyzes the synthesis of GMP from XMP
CE463_11915	COG0518	GMP synthase (glutamine-hydrolyzing) activity
CE463_11975	COG2062	phosphohistidine phosphatase, SixA
CE463_11985	COG0697	spore germination
CE463_11990	COG4166	transmembrane transport
CE463_11995	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
CE463_12000	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
CE463_12010	COG4591	ABC-type transport system involved in lipoprotein release permease component
CE463_12015	COG1136	(ABC) transporter
CE463_12020	COG4591	ABC-type transport system involved in lipoprotein release permease component
CE463_12025	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
CE463_12040	COG0544	peptidyl-prolyl cis-trans isomerase activity
CE463_12045	COG0740	serine-type endopeptidase activity
CE463_12050	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
CE463_12055	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
CE463_12060	COG0776	regulation of translation
CE463_12065	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CE463_12070	COG0488	(ABC) transporter
CE463_12075	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CE463_12080	COG3162	membrane
CE463_12095	COG1024	Enoyl-CoA hydratase
CE463_12095	COG1250	3-hydroxyacyl-CoA dehydrogenase
CE463_12100	COG1115	amino acid carrier protein
CE463_12105	COG0456	acetyltransferase
CE463_12115	COG1584	GPR1 FUN34 yaaH family protein
CE463_12145	COG1024	Enoyl-CoA hydratase
CE463_12150	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
CE463_12175	COG1960	acyl-CoA dehydrogenase activity
CE463_12180	COG1024	Enoyl-CoA hydratase
CE463_12185	COG1024	Enoyl-CoA hydratase
CE463_12195	COG1028	Short-chain dehydrogenase reductase Sdr
CE463_12205	COG0730	response to heat
CE463_12240	COG2378	regulation of single-species biofilm formation
CE463_12250	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
CE463_12250	COG0140	phosphoribosyl-ATP diphosphatase activity
CE463_12255	COG0107	imidazoleglycerol-phosphate synthase activity
CE463_12260	COG2198	Histidine kinase
CE463_12260	COG2205	protein histidine kinase activity
CE463_12260	COG0784	Response regulator, receiver
CE463_12270	COG3437	response regulator, receiver
CE463_12275	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
CE463_12280	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
CE463_12285	COG0131	Imidazoleglycerol-phosphate dehydratase
CE463_12285	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
CE463_12290	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CE463_12295	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
CE463_12300	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
CE463_12310	COG1199	ATP-dependent helicase activity
CE463_12315	COG1214	PFAM Peptidase M22, glycoprotease
CE463_12325	COG2267	carboxylic ester hydrolase activity
CE463_12330	COG0318	PFAM AMP-dependent synthetase and ligase
CE463_12350	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CE463_12355	COG2832	Protein of unknown function (DUF454)
CE463_12360	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
CE463_12365	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
CE463_12370	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
CE463_12380	COG2197	response regulator
CE463_12390	COG1643	Atp-dependent helicase
CE463_12400	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
CE463_12405	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CE463_12410	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
CE463_12415	COG0709	Synthesizes selenophosphate from selenide and ATP
CE463_12430	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
CE463_12440	COG1254	Belongs to the acylphosphatase family
CE463_12445	COG0625	glutathione transferase activity
CE463_12450	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CE463_12450	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CE463_12455	COG0489	protein tyrosine kinase activity
CE463_12460	COG0572	uridine kinase
CE463_12465	COG0717	Belongs to the dCTP deaminase family
CE463_12470	COG0306	phosphate transporter
CE463_12475	COG1530	ribonuclease E activity
CE463_12485	COG0546	phosphoglycolate phosphatase activity
CE463_12490	COG0424	maF-like protein
CE463_12495	COG1399	metal-binding, possibly nucleic acid-binding protein
CE463_12500	COG0333	Belongs to the bacterial ribosomal protein bL32 family
CE463_12505	COG0416	fatty acid biosynthetic process
CE463_12510	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CE463_12520	COG1028	Short-chain dehydrogenase reductase Sdr
CE463_12525	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CE463_12530	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CE463_12535	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CE463_12540	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
CE463_12545	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
CE463_12550	COG0470	DNA polymerase III
CE463_12555	COG0084	hydrolase, TatD family'
CE463_12570	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
CE463_12570	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
CE463_12580	COG2995	paraquat-inducible protein a
CE463_12590	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
CE463_12595	COG0372	Belongs to the citrate synthase family
CE463_12640	COG4221	oxidoreductase activity
CE463_12670	COG3620	sequence-specific DNA binding
CE463_12735	COG5433	transposase activity
CE463_12745	COG1067	ATP-dependent peptidase activity
CE463_12750	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
CE463_12775	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
CE463_12775	COG0116	Belongs to the methyltransferase superfamily
CE463_12790	COG0167	dihydroorotate dehydrogenase activity
CE463_12800	COG5433	transposase activity
CE463_12815	COG0308	aminopeptidase N
CE463_12825	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
CE463_12830	COG1956	GAF domain-containing protein
CE463_12840	COG3278	Belongs to the heme-copper respiratory oxidase family
CE463_12855	COG2010	Cytochrome c
CE463_12865	COG2217	Heavy metal translocating P-type atpase
CE463_12880	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CE463_12885	COG0589	response to stress
CE463_12890	COG0037	tRNA processing
CE463_12910	COG1869	D-ribose catabolic process
CE463_12920	COG1172	Belongs to the binding-protein-dependent transport system permease family
CE463_12925	COG1879	ABC-type sugar transport system periplasmic component
CE463_12930	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CE463_12935	COG1609	Transcriptional regulator
CE463_12955	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
CE463_12970	COG2205	protein histidine kinase activity
CE463_12970	COG0784	Response regulator, receiver
CE463_12975	COG0776	regulation of translation
CE463_12980	COG0072	phenylalanine-tRNA ligase activity
CE463_12980	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CE463_12985	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
CE463_12990	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
CE463_12995	COG0291	Belongs to the bacterial ribosomal protein bL35 family
CE463_13000	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
CE463_13005	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
CE463_13025	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
CE463_13035	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CE463_13040	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CE463_13045	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CE463_13050	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
CE463_13055	COG3313	Fe-S protein
CE463_13060	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CE463_13060	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CE463_13060	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
CE463_13065	COG1105	Belongs to the carbohydrate kinase PfkB family
CE463_13070	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CE463_13070	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
CE463_13075	COG1609	Transcriptional regulator
CE463_13080	COG0814	amino acid
CE463_13090	COG5654	RES domain protein
CE463_13095	COG0513	Belongs to the DEAD box helicase family
CE463_13105	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
CE463_13110	COG2890	protein-(glutamine-N5) methyltransferase activity
CE463_13115	COG2840	Smr protein MutS2
CE463_13120	COG3706	GGDEF domain
CE463_13170	COG2824	Alkylphosphonate utilization operon protein PhnA
CE463_13175	COG1250	3-hydroxyacyl-CoA dehydrogenase
CE463_13175	COG1024	Enoyl-CoA hydratase
CE463_13180	COG0183	Belongs to the thiolase family
CE463_13185	COG0714	Associated with various cellular activities
CE463_13225	COG2067	long-chain fatty acid transport protein
CE463_13230	COG2067	long-chain fatty acid transport protein
CE463_13235	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
CE463_13255	COG3123	guanosine phosphorylase activity
CE463_13260	COG1760	l-serine dehydratase
CE463_13270	COG1760	l-serine dehydratase
CE463_13275	COG2951	lytic endotransglycosylase activity
CE463_13280	COG3100	YcgL domain-containing protein
CE463_13285	COG0850	regulation of cytokinetic process
CE463_13290	COG2894	cell division
CE463_13295	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
CE463_13305	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CE463_13350	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
CE463_13355	COG0697	spore germination
CE463_13360	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
CE463_13365	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CE463_13375	COG0307	riboflavin synthase, alpha
CE463_13385	COG0534	Mate efflux family protein
CE463_13420	COG0417	DNA replication proofreading
CE463_13450	COG1560	Kdo2-lipid A biosynthetic process
CE463_13460	COG0583	DNA-binding transcription factor activity
CE463_13465	COG0673	inositol 2-dehydrogenase activity
CE463_13470	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
CE463_13475	COG0583	DNA-binding transcription factor activity
CE463_13485	COG2723	6-phospho-beta-galactosidase activity
CE463_13490	COG0583	DNA-binding transcription factor activity
CE463_13510	COG1288	antiporter activity
CE463_13520	COG3134	Outer membrane lipoprotein
CE463_13540	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CE463_13560	COG4681	YaeQ
CE463_13605	COG0242	peptide deformylase activity
CE463_13630	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
CE463_13635	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
CE463_13640	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
CE463_13650	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
CE463_13660	COG1434	Gram-negative-bacterium-type cell wall biogenesis
CE463_13670	COG0205	6-phosphofructokinase activity
CE463_13705	COG1011	Hydrolase
CE463_13760	COG3593	DNA synthesis involved in DNA repair
CE463_13775	COG0583	DNA-binding transcription factor activity
CE463_13780	COG0730	response to heat
CE463_13795	COG1181	Belongs to the D-alanine--D-alanine ligase family
CE463_13805	COG0386	Belongs to the glutathione peroxidase family
CE463_13810	COG0513	Belongs to the DEAD box helicase family
CE463_13825	COG1742	UPF0060 membrane protein
CE463_13860	COG2329	Antibiotic biosynthesis monooxygenase
CE463_13865	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
CE463_13885	COG3243	poly(R)-hydroxyalkanoic acid synthase
CE463_13895	COG2501	S4 domain
CE463_13905	COG1132	(ABC) transporter
CE463_13920	COG3118	belongs to the thioredoxin family
CE463_13925	COG0471	metal ion transport
CE463_13930	COG0058	SHG alpha-glucan phosphorylase activity
CE463_13975	COG5433	transposase activity
CE463_14000	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
CE463_14010	COG0814	amino acid
CE463_14015	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
CE463_14020	COG0514	ATP-dependent DNA helicase (RecQ)
CE463_14025	COG2766	serine protein kinase
CE463_14035	COG2719	SpoVR family
CE463_14040	COG2186	Transcriptional regulator
CE463_14045	COG3067	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
CE463_14050	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
CE463_14055	COG0586	Pfam SNARE associated Golgi protein
CE463_14065	COG0556	nucleotide-excision repair
CE463_14080	COG2985	domain, Protein
CE463_14080	COG0569	domain protein
CE463_14085	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
CE463_14090	COG5433	transposase activity
CE463_14120	COG4565	transcriptional regulatory protein
CE463_14125	COG3290	protein histidine kinase activity
CE463_14130	COG1940	carbohydrate kinase activity
CE463_14130	COG1846	Transcriptional regulator
CE463_14135	COG0840	transmembrane signaling receptor activity
CE463_14140	COG3012	SEC-C Motif Domain Protein
CE463_14145	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
CE463_14150	COG3075	Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses fumarate or nitrate as electron acceptor
CE463_14155	COG0247	lactate metabolic process
CE463_14165	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
CE463_14170	COG0437	4 iron, 4 sulfur cluster binding
CE463_14175	COG3301	Polysulphide reductase, NrfD
CE463_14190	COG4235	cytochrome complex assembly
CE463_14190	COG3088	subunit of a heme lyase
CE463_14205	COG3033	Beta-eliminating lyase
CE463_14215	COG3046	protein related to deoxyribodipyrimidine photolyase
CE463_14245	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
CE463_14250	COG0583	DNA-binding transcription factor activity
CE463_14260	COG4774	siderophore transport
CE463_14265	COG3708	Transcriptional regulator
CE463_14265	COG2207	Transcriptional regulator
CE463_14275	COG0583	DNA-binding transcription factor activity
CE463_14280	COG2910	NAD(P)H-binding
CE463_14300	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
CE463_14305	COG1944	ATP diphosphatase activity
CE463_14310	COG2116	formate transmembrane transporter activity
CE463_14315	COG1882	Formate acetyltransferase
CE463_14325	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
CE463_14330	COG0045	succinate-CoA ligase (ADP-forming) activity
CE463_14335	COG0508	dehydrogenase complex catalyzes the overall conversion of
CE463_14340	COG0567	Dehydrogenase, E1 component
CE463_14350	COG1053	succinate dehydrogenase
CE463_14355	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
CE463_14360	COG2009	succinate dehydrogenase
CE463_14380	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CE463_14385	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
CE463_14385	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CE463_14395	COG3069	C4-dicarboxylate transmembrane transporter activity
CE463_14410	COG1451	nucleotide metabolic process
CE463_14425	COG0254	rRNA binding
CE463_14430	COG0257	Belongs to the bacterial ribosomal protein bL36 family
CE463_14450	COG3867	Arabinogalactan endo-beta-1,4-galactanase
CE463_14455	COG3833	ABC-type maltose transport systems, permease component
CE463_14520	COG4580	involved in the transport of maltose and maltodextrins
CE463_14530	COG1609	Transcriptional regulator
CE463_14535	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
CE463_14555	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
CE463_14565	COG1172	Belongs to the binding-protein-dependent transport system permease family
CE463_14570	COG1129	ABC transporter
CE463_14575	COG1879	ABC-type sugar transport system periplasmic component
CE463_14580	COG1069	ribulokinase activity
CE463_14590	COG2160	L-arabinose isomerase activity
CE463_14595	COG0583	DNA-binding transcription factor activity
CE463_14600	COG0436	Aminotransferase
CE463_14605	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CE463_14620	COG2925	Exonuclease
CE463_14630	COG3345	alpha-galactosidase
CE463_14640	COG1380	Effector of murein hydrolase LrgA
CE463_14645	COG1346	cytolysis
CE463_14650	COG0295	cytidine deaminase activity
CE463_14655	COG1022	Amp-dependent synthetase and ligase
CE463_14670	COG0861	Integral membrane protein TerC family
CE463_14680	COG2199	diguanylate cyclase activity
CE463_14695	COG2154	pterin-4-alpha-carbinolamine dehydratase
CE463_14705	COG3768	UPF0283 membrane protein
CE463_14710	COG3106	COG3106 Predicted ATPase
CE463_14725	COG1842	Phage shock protein A
CE463_14730	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
CE463_14740	COG4168	peptide transport system, permease
CE463_14745	COG4171	peptide transport system, permease
CE463_14750	COG4172	Belongs to the ABC transporter superfamily
CE463_14755	COG4172	Belongs to the ABC transporter superfamily
CE463_14765	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
CE463_14770	COG1286	toxin biosynthetic process
CE463_14775	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
CE463_14780	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
CE463_14785	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
CE463_14790	COG1674	ftsk spoiiie
CE463_14790	COG0531	amino acid
CE463_14810	COG0492	ferredoxin-NADP+ reductase activity
CE463_14820	COG3134	Outer membrane lipoprotein
CE463_14825	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
CE463_14830	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
CE463_14835	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
CE463_14840	COG0542	response to heat
CE463_14845	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
CE463_14850	COG1278	Cold shock
CE463_14855	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
CE463_14980	COG0659	secondary active sulfate transmembrane transporter activity
CE463_15030	COG0697	spore germination
CE463_15035	COG4657	Part of a membrane complex involved in electron transport
CE463_15040	COG2878	Part of a membrane complex involved in electron transport
CE463_15050	COG4658	electron transport chain
CE463_15055	COG4659	FMN binding
CE463_15065	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
CE463_15070	COG0346	lactoylglutathione lyase activity
CE463_15085	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CE463_15090	COG2056	Na+-H+ antiporter family
CE463_15095	COG5001	Diguanylate cyclase
CE463_15095	COG3300	MHYT domain
CE463_15105	COG0513	Belongs to the DEAD box helicase family
CE463_15110	COG2050	protein possibly involved in aromatic compounds catabolism
CE463_15120	COG0247	lactate metabolic process
CE463_15120	COG0277	FAD linked oxidase domain protein
CE463_15130	COG1253	flavin adenine dinucleotide binding
CE463_15135	COG1902	pentaerythritol trinitrate reductase activity
CE463_15145	COG0647	UMP catabolic process
CE463_15150	COG4651	solute:proton antiporter activity
CE463_15150	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
CE463_15160	COG0367	asparagine synthase
CE463_15185	COG0625	glutathione transferase activity
CE463_15190	COG0625	glutathione transferase activity
CE463_15215	COG0564	pseudouridine synthase activity
CE463_15235	COG0840	transmembrane signaling receptor activity
CE463_15245	COG0670	Belongs to the BI1 family
CE463_15250	COG1289	transmembrane transporter activity
CE463_15255	COG2920	part of a sulfur-relay system
CE463_15260	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
CE463_15265	COG0285	dihydrofolate synthase activity
CE463_15270	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
CE463_15275	COG0101	tRNA pseudouridine synthase activity
CE463_15285	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
CE463_15290	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CE463_15295	COG0671	phosphoesterase, PA-phosphatase related
CE463_15325	COG5433	transposase activity
CE463_15360	COG0574	Belongs to the PEP-utilizing enzyme family
CE463_15360	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CE463_15365	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
CE463_15420	COG0672	)-iron permease
CE463_15445	COG2814	Major facilitator Superfamily
CE463_15460	COG1136	(ABC) transporter
CE463_15480	COG1285	pathogenesis
CE463_15530	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CE463_15535	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
CE463_15535	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
CE463_15540	COG0527	aspartate kinase activity
CE463_15550	COG1368	sulfuric ester hydrolase activity
CE463_15555	COG1619	proteins homologs of microcin C7 resistance protein MccF
CE463_15565	COG0393	Putative heavy-metal-binding
CE463_15570	COG1252	NADH dehydrogenase
CE463_15610	COG0789	Transcriptional regulator
CE463_15625	COG0493	'glutamate synthase
CE463_15630	COG0069	glutamate synthase activity
CE463_15630	COG0070	glutamate synthase
CE463_15630	COG0067	glutamate synthase
CE463_15635	COG5433	transposase activity
CE463_15675	COG0513	Belongs to the DEAD box helicase family
CE463_15680	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CE463_15710	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CE463_15715	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
CE463_15720	COG0505	Belongs to the CarA family
CE463_15725	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
CE463_15740	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
CE463_15745	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
CE463_15750	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CE463_15755	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
CE463_15760	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
CE463_15765	COG4138	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system
CE463_15775	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CE463_15775	COG2205	protein histidine kinase activity
CE463_15815	COG0023	Translation Initiation Factor
CE463_15820	COG2119	membrane
CE463_15850	COG2203	Gaf domain
CE463_15850	COG2199	diguanylate cyclase activity
CE463_15880	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
CE463_15890	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CE463_15895	COG2261	transglycosylase associated protein
CE463_15935	COG0322	excinuclease ABC activity
CE463_15940	COG2197	response regulator
CE463_15945	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
CE463_15950	COG2835	tetraacyldisaccharide 4'-kinase activity
CE463_15955	COG1663	tetraacyldisaccharide 4'-kinase activity
CE463_15960	COG1132	(ABC) transporter
CE463_15965	COG0658	competence protein
CE463_15965	COG2333	competence protein COMEC
CE463_15980	COG0433	COG0433 Predicted ATPase
CE463_15985	COG1448	Aminotransferase
CE463_15995	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
CE463_16000	COG1199	ATP-dependent helicase activity
CE463_16020	COG1785	Belongs to the alkaline phosphatase family
CE463_16040	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CE463_16055	COG2271	Major facilitator Superfamily
CE463_16060	COG3706	GGDEF domain
CE463_16065	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CE463_16070	COG0765	amino acid transport
CE463_16075	COG1126	abc transporter atp-binding protein
CE463_16085	COG0531	amino acid
CE463_16100	COG1253	flavin adenine dinucleotide binding
CE463_16105	COG0704	Plays a role in the regulation of phosphate uptake
CE463_16115	COG0581	inorganic phosphate transmembrane transporter activity
CE463_16120	COG0573	inorganic phosphate transmembrane transporter activity
CE463_16125	COG0590	tRNA wobble adenosine to inosine editing
CE463_16135	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
CE463_16155	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
CE463_16160	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
CE463_16165	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
CE463_16170	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
CE463_16175	COG2204	response regulator
CE463_16180	COG3852	Histidine kinase
CE463_16200	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
CE463_16205	COG0248	Ppx GppA phosphatase
CE463_16210	COG2239	Acts as a magnesium transporter
CE463_16240	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
CE463_16245	COG4786	Flagellar basal body rod
CE463_16250	COG4787	bacterial-type flagellum-dependent cell motility
CE463_16265	COG1558	bacterial-type flagellum-dependent cell motility
CE463_16270	COG1815	bacterial-type flagellum-dependent cell motility
CE463_16275	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
CE463_16280	COG0784	Response regulator, receiver
CE463_16280	COG0835	chemotaxis
CE463_16300	COG0622	Phosphoesterase
CE463_16305	COG4166	transmembrane transport
CE463_16315	COG1187	pseudouridine synthase activity
CE463_16335	COG0697	spore germination
CE463_16375	COG1278	Cold shock
CE463_16430	COG3132	Protein of unknown function, DUF480
CE463_16445	COG5433	transposase activity
CE463_16465	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CE463_16480	COG5433	transposase activity
CE463_16495	COG0471	metal ion transport
CE463_16495	COG3273	potassium ion transport
CE463_16500	COG5433	transposase activity
CE463_16520	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
CE463_16525	COG0438	transferase activity, transferring glycosyl groups
CE463_16545	COG1450	Type ii and iii secretion system protein
CE463_16580	COG1459	type II secretion system
CE463_16585	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
CE463_16605	COG1091	dTDP-4-dehydrorhamnose reductase activity
CE463_16615	COG1538	Outer membrane efflux protein
CE463_16630	COG1309	transcriptional regulator
CE463_16645	COG1946	Acyl-CoA thioesterase
CE463_16655	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
CE463_16665	COG0009	L-threonylcarbamoyladenylate synthase
CE463_16670	COG0613	PHP domain protein
CE463_16675	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
CE463_16680	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
CE463_16680	COG0512	Glutamine amidotransferase of anthranilate synthase
CE463_16685	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
CE463_16690	COG0135	phosphoribosylanthranilate isomerase activity
CE463_16690	COG0134	indole-3-glycerol-phosphate synthase activity
CE463_16695	COG0133	tryptophan synthase activity
CE463_16700	COG0159	tryptophan synthase activity
CE463_16755	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CE463_16755	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CE463_16755	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CE463_16765	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CE463_16785	COG0482	sulfurtransferase activity
CE463_16790	COG2915	High frequency lysogenization protein hflD homolog
CE463_16795	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
CE463_16800	COG2850	peptidyl-arginine hydroxylation
CE463_16855	COG0259	pyridoxamine-phosphate oxidase activity
CE463_16870	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CE463_16870	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
CE463_16875	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
CE463_16895	COG3088	subunit of a heme lyase
CE463_16895	COG4235	cytochrome complex assembly
CE463_16900	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CE463_16905	COG1138	Cytochrome C-type biogenesis protein
CE463_16910	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
CE463_16915	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CE463_16920	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CE463_16925	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CE463_16940	COG0835	chemotaxis
CE463_16950	COG1192	Involved in chromosome partitioning
CE463_16955	COG1360	Flagellar Motor Protein
CE463_16960	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
CE463_16965	COG2201	protein-glutamate methylesterase activity
CE463_16970	COG0643	Histidine kinase
CE463_16970	COG2198	Histidine kinase
CE463_16980	COG0583	DNA-binding transcription factor activity
CE463_16990	COG0791	NLP P60 protein
CE463_17005	COG1309	transcriptional regulator
CE463_17045	COG0534	Mate efflux family protein
CE463_17055	COG2841	Protein conserved in bacteria
CE463_17060	COG1013	pyruvate-flavodoxin oxidoreductase activity
CE463_17060	COG0674	pyruvate-flavodoxin oxidoreductase activity
CE463_17060	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
CE463_17060	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
CE463_17075	COG0633	Ferredoxin
CE463_17075	COG3217	Mosc domain protein beta barrel domain protein
CE463_17075	COG0633	Ferredoxin
CE463_17075	COG3217	Mosc domain protein beta barrel domain protein
CE463_17085	COG0501	Belongs to the peptidase M48B family
CE463_17090	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
CE463_17095	COG2226	methyltransferase
CE463_17095	COG1073	alpha beta
CE463_17100	COG0156	8-amino-7-oxononanoate synthase activity
CE463_17105	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
CE463_17125	COG0017	Asparaginyl-tRNA synthetase
CE463_17145	COG0583	DNA-binding transcription factor activity
CE463_17150	COG1393	Belongs to the ArsC family
CE463_17155	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CE463_17160	COG1876	peptidase activity
CE463_17170	COG3263	regulation of cellular component size
CE463_17190	COG5433	transposase activity
CE463_17200	COG0564	pseudouridine synthase activity
CE463_17205	COG3098	single-species biofilm formation
CE463_17230	COG5595	Zn-ribbon-containing, possibly nucleic-acid-binding protein (DUF2310)
CE463_17240	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
CE463_17240	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
CE463_17250	COG3706	GGDEF domain
CE463_17255	COG1611	Belongs to the LOG family
CE463_17260	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CE463_17265	COG0473	3-isopropylmalate dehydrogenase activity
CE463_17275	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
CE463_17280	COG2363	Small membrane protein
CE463_17290	COG0583	DNA-binding transcription factor activity
CE463_17295	COG0840	transmembrane signaling receptor activity
CE463_17300	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CE463_17315	COG1477	protein flavinylation
CE463_17320	COG2871	sodium ion transport
CE463_17325	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
CE463_17330	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
CE463_17335	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
CE463_17340	COG1805	sodium ion transport
CE463_17345	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
CE463_17350	COG0271	Belongs to the BolA IbaG family
CE463_17360	COG2813	Specifically methylates the guanine in position
CE463_17370	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
CE463_17380	COG2211	Major facilitator Superfamily
CE463_17385	COG3248	Nucleoside-binding outer membrane protein
CE463_17390	COG1666	GTP binding
CE463_17395	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
CE463_17400	COG0693	protein deglycase activity
CE463_17420	COG3459	Glycosyltransferase 36 associated
CE463_17435	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
CE463_17435	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
CE463_17440	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
CE463_17450	COG1151	hydroxylamine reductase activity
CE463_17455	COG0783	Belongs to the Dps family
CE463_17480	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
CE463_17495	COG0300	oxidoreductase activity
CE463_17505	COG0415	Belongs to the DNA photolyase family
CE463_17510	COG0789	Transcriptional regulator
CE463_17515	COG3272	Protein of unknown function (DUF1722)
CE463_17545	COG0077	Prephenate dehydratase
CE463_17545	COG1605	Chorismate mutase
CE463_17570	COG2133	pyrroloquinoline quinone binding
CE463_17595	COG0300	oxidoreductase activity
CE463_17620	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
CE463_17635	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CE463_17645	COG3813	Protein conserved in bacteria
CE463_17660	COG1280	lysine exporter protein (LysE YggA)
CE463_17670	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CE463_17700	COG0835	chemotaxis
CE463_17705	COG0840	transmembrane signaling receptor activity
CE463_17735	COG5433	transposase activity
CE463_17740	COG1917	Cupin 2, conserved barrel domain protein
CE463_17740	COG2169	Transcriptional regulator
CE463_17750	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CE463_17755	COG1917	Cupin 2, conserved barrel domain protein
CE463_17755	COG1396	sequence-specific DNA binding
CE463_17770	COG0531	amino acid
CE463_17775	COG0531	amino acid
CE463_17780	COG1283	sodium-dependent phosphate transmembrane transporter activity
CE463_17790	COG3384	dioxygenase
CE463_17805	COG0813	purine-nucleoside phosphorylase activity
CE463_17830	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
CE463_17835	COG0083	homoserine kinase activity
CE463_17845	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
CE463_17850	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
CE463_17865	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
CE463_17875	COG0745	RESPONSE REGULATOR receiver
CE463_17890	COG4988	ABC transporter
CE463_17895	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
CE463_17915	COG1720	tRNA m6t6A37 methyltransferase activity
CE463_17935	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
CE463_17940	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CE463_17950	COG2190	(PTS) system
CE463_17955	COG3706	GGDEF domain
CE463_17965	COG3038	cytochrome b561
CE463_17975	COG5433	transposase activity
CE463_17985	COG0419	ATPase involved in DNA repair
CE463_17990	COG0420	3'-5' exonuclease activity
CE463_18000	COG2974	May be involved in recombination
CE463_18005	COG0405	Gamma-glutamyltransferase
CE463_18010	COG4651	solute:proton antiporter activity
CE463_18010	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
CE463_18015	COG4651	solute:proton antiporter activity
CE463_18015	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
CE463_18030	COG0469	pyruvate kinase activity
CE463_18035	COG3264	Mechanosensitive ion channel
CE463_18035	COG1196	nuclear chromosome segregation
CE463_18040	COG0582	viral genome integration into host DNA
CE463_18055	COG1846	Transcriptional regulator
CE463_18060	COG1566	PFAM secretion protein HlyD family protein
CE463_18085	COG0602	queuosine metabolic process
CE463_18095	COG1328	CTP reductase activity
CE463_18105	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
CE463_18110	COG3115	cell septum assembly
CE463_18115	COG1196	nuclear chromosome segregation
CE463_18125	COG2860	membrane
CE463_18135	COG3108	Peptidase M15
CE463_18140	COG2989	Protein conserved in bacteria
CE463_18155	COG0463	Glycosyl transferase, family 2
CE463_18175	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
CE463_18180	COG0739	heme binding
CE463_18185	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
CE463_18205	COG5433	transposase activity
CE463_18210	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
CE463_18220	COG3091	SprT-like family
CE463_18230	COG1385	rRNA (uridine-N3-)-methyltransferase activity
CE463_18235	COG0189	ligase activity
CE463_18255	COG1678	Uncharacterized ACR, COG1678
CE463_18260	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
CE463_18265	COG0583	DNA-binding transcription factor activity
CE463_18280	COG0714	Associated with various cellular activities
CE463_18295	COG1115	amino acid carrier protein
CE463_18300	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
CE463_18315	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
CE463_18355	COG2912	Transglutaminase-like superfamily
CE463_18365	COG2890	protein-(glutamine-N5) methyltransferase activity
CE463_18370	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
CE463_18375	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
CE463_18380	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
CE463_18385	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
CE463_18395	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
CE463_18400	COG0737	Belongs to the 5'-nucleotidase family
CE463_18405	COG0193	aminoacyl-tRNA hydrolase activity
CE463_18410	COG0012	GTP binding
CE463_18455	COG0471	metal ion transport
CE463_18455	COG0490	domain, Protein
CE463_18465	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
CE463_18500	COG0443	Heat shock 70 kDa protein
CE463_18515	COG0366	Alpha amylase catalytic
CE463_18530	COG0488	(ABC) transporter
CE463_18550	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CE463_18560	COG1012	belongs to the aldehyde dehydrogenase family
CE463_18570	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CE463_18585	COG0180	Tryptophanyl-tRNA synthetase
CE463_18590	COG0546	phosphoglycolate phosphatase activity
CE463_18595	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
CE463_18600	COG0338	D12 class N6 adenine-specific DNA methyltransferase
CE463_18610	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
CE463_18615	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
CE463_18645	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
CE463_18650	COG0583	DNA-binding transcription factor activity
CE463_18655	COG0840	transmembrane signaling receptor activity
CE463_18670	COG0583	DNA-binding transcription factor activity
CE463_18685	COG0739	heme binding
CE463_18715	COG0584	glycerophosphoryl diester phosphodiesterase
CE463_18725	COG1053	succinate dehydrogenase
CE463_18730	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
CE463_18735	COG3029	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
CE463_18740	COG3080	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
CE463_18760	COG3214	Protein conserved in bacteria
CE463_18795	COG0745	RESPONSE REGULATOR receiver
CE463_18800	COG0642	Histidine kinase
CE463_18810	COG0516	GMP reductase activity
CE463_18820	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
CE463_18830	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CE463_18850	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CE463_18865	COG3706	GGDEF domain
CE463_18875	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CE463_18880	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CE463_18885	COG1702	phosphate starvation-inducible protein PhoH
CE463_18890	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
CE463_18895	COG4535	Mg2 and Co2 transporter CorC
CE463_18900	COG0815	Transfers the fatty acyl group on membrane lipoproteins
CE463_18905	COG2888	peptidyl-tyrosine sulfation
CE463_18910	COG0495	leucyl-tRNA aminoacylation
CE463_18930	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
CE463_18935	COG0799	negative regulation of ribosome biogenesis
CE463_18940	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
CE463_18945	COG0768	penicillin binding
CE463_18950	COG0772	Belongs to the SEDS family
CE463_18955	COG2951	lytic endotransglycosylase activity
CE463_18960	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
CE463_18965	COG1686	Belongs to the peptidase S11 family
CE463_18970	COG2921	Belongs to the UPF0250 family
CE463_18975	COG0321	lipoyl(octanoyl) transferase activity
CE463_18985	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
CE463_19000	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CE463_19005	COG3545	Serine hydrolase
CE463_19020	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
CE463_19030	COG1970	mechanosensitive ion channel activity
CE463_19035	COG3706	GGDEF domain
CE463_19040	COG4974	Belongs to the 'phage' integrase family
CE463_19045	COG0716	FMN binding
CE463_19055	COG0312	modulator of DNA gyrase
CE463_19100	COG5433	transposase activity
CE463_19115	COG1422	Protein of unknown function (DUF1090)
CE463_19120	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
CE463_19125	COG3706	GGDEF domain
CE463_19130	COG2211	Major facilitator Superfamily
CE463_19135	COG1185	polyribonucleotide nucleotidyltransferase activity
CE463_19140	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
CE463_19145	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
CE463_19150	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
CE463_19155	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
CE463_19160	COG0195	Participates in both transcription termination and antitermination
CE463_19165	COG0779	Required for maturation of 30S ribosomal subunits
CE463_19180	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
CE463_19185	COG0149	triose-phosphate isomerase activity
CE463_19190	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CE463_19195	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
CE463_19200	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CE463_19205	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
CE463_19210	COG1534	Rna-binding protein
CE463_19220	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CE463_19235	COG1360	Flagellar Motor Protein
CE463_19240	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
CE463_19245	COG1722	exodeoxyribonuclease VII activity
CE463_19250	COG0142	geranyltranstransferase activity
CE463_19255	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
CE463_19280	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
CE463_19285	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
CE463_19290	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CE463_19295	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
CE463_19310	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CE463_19310	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CE463_19315	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
CE463_19330	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
CE463_19350	COG3381	protein complex oligomerization
CE463_19380	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CE463_19385	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
CE463_19390	COG0511	ligase activity, forming carbon-carbon bonds
CE463_19395	COG0439	Biotin carboxylase
CE463_19400	COG3924	membrane
CE463_19405	COG4145	pantothenate transmembrane transporter activity
CE463_19410	COG2190	(PTS) system
CE463_19410	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CE463_19410	COG1263	PTS System
CE463_19415	COG0583	DNA-binding transcription factor activity
CE463_19420	COG0604	alcohol dehydrogenase
CE463_19425	COG2264	protein methyltransferase activity
CE463_19430	COG0531	amino acid
CE463_19435	COG4303	Ethanolamine ammonia lyase large subunit
CE463_19440	COG4302	ethanolamine ammonia-lyase activity
CE463_19460	COG0778	Nitroreductase
CE463_19465	COG0446	pyridine nucleotide-disulphide oxidoreductase
CE463_19465	COG1902	pentaerythritol trinitrate reductase activity
CE463_19470	COG0616	signal peptide processing
CE463_19490	COG3139	Protein of unknown function (DUF1315)
CE463_19495	COG0252	asparaginase activity
CE463_19500	COG0786	glutamate:sodium symporter activity
CE463_19515	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
CE463_19520	COG0384	phenazine biosynthesis protein PhzF
CE463_19525	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
CE463_19530	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CE463_19535	COG0175	sulfate reduction
CE463_19540	COG2113	Glycine betaine
CE463_19545	COG4176	ABC-type proline glycine betaine transport system permease component
CE463_19550	COG4175	Glycine betaine
CE463_19560	COG3610	response to peptide
CE463_19565	COG2966	Psort location CytoplasmicMembrane, score
CE463_19580	COG0521	Mo-molybdopterin cofactor biosynthetic process
CE463_19590	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CE463_19595	COG1028	Short-chain dehydrogenase reductase Sdr
CE463_19605	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CE463_19630	COG2986	histidine ammonia-lyase
CE463_19645	COG0318	PFAM AMP-dependent synthetase and ligase
CE463_19655	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CE463_19660	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CE463_19705	COG1858	cytochrome C peroxidase
CE463_19710	COG5433	transposase activity
CE463_19720	COG2313	pseudouridylate synthase activity
CE463_19725	COG1522	sequence-specific DNA binding
CE463_19725	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CE463_19755	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
CE463_19760	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
CE463_19775	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
CE463_19790	COG2195	Cleaves the N-terminal amino acid of tripeptides
CE463_19800	COG4608	Belongs to the ABC transporter superfamily
CE463_19805	COG0444	Belongs to the ABC transporter superfamily
CE463_19810	COG0747	negative chemotaxis
CE463_19815	COG4239	(ABC) transporter, permease
CE463_19835	COG5433	transposase activity
CE463_19840	COG4206	TonB-dependent receptor
CE463_19850	COG0811	peptide transport
CE463_19855	COG0811	peptide transport
CE463_19860	COG0848	biopolymer transport protein
CE463_19915	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CE463_19930	COG1278	Cold shock
CE463_19970	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
CE463_19980	COG0688	phosphatidylethanolamine metabolic process
CE463_19985	COG4628	conserved protein (DUF2132)
CE463_20005	COG3300	MHYT domain
CE463_20005	COG5001	Diguanylate cyclase
CE463_20010	COG3076	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome
CE463_20015	COG3291	Pkd domain containing protein
CE463_20015	COG4412	M6 family metalloprotease domain protein
CE463_20040	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
CE463_20045	COG1012	belongs to the aldehyde dehydrogenase family
CE463_20060	COG1132	(ABC) transporter
CE463_20070	COG2897	thiosulfate sulfurtransferase activity
CE463_20075	COG2066	Belongs to the glutaminase family
CE463_20080	COG3171	Protein conserved in bacteria
CE463_20085	COG0220	tRNA (guanine-N7-)-methyltransferase activity
CE463_20090	COG4935	Belongs to the peptidase S8 family
CE463_20090	COG2234	aminopeptidase activity
CE463_20095	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CE463_20100	COG2200	EAL domain
CE463_20105	COG1090	epimerase
CE463_20110	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
CE463_20115	COG4181	ATPase activity
CE463_20120	COG2755	lipolytic protein G-D-S-L family
CE463_20125	COG0784	Response regulator, receiver
CE463_20125	COG0835	chemotaxis
CE463_20135	COG2985	domain, Protein
CE463_20135	COG0569	domain protein
CE463_20140	COG1272	protein, Hemolysin III
CE463_20145	COG0076	glutamate decarboxylase activity
CE463_20150	COG2917	probably involved in intracellular septation
CE463_20155	COG2350	Protein conserved in bacteria
CE463_20165	COG1555	photosystem II stabilization
CE463_20170	COG1210	Utp--glucose-1-phosphate uridylyltransferase
CE463_20175	COG3104	oligopeptide transport
CE463_20180	COG0745	RESPONSE REGULATOR receiver
CE463_20210	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CE463_20225	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
CE463_20230	COG1280	lysine exporter protein (LysE YggA)
CE463_20290	COG1912	Pfam S-adenosyl-l-methionine hydroxide adenosyltransferase
CE463_20310	COG0513	Belongs to the DEAD box helicase family
CE463_20450	COG0582	viral genome integration into host DNA
CE463_20465	COG0795	lipopolysaccharide-transporting ATPase activity
CE463_20470	COG0795	lipopolysaccharide-transporting ATPase activity
CE463_20475	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
CE463_20480	COG2927	DNA polymerase III (CHI subunit)
CE463_20495	COG0586	Pfam SNARE associated Golgi protein
CE463_20500	COG1686	Belongs to the peptidase S11 family
CE463_20525	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
CE463_20530	COG0527	aspartate kinase activity
CE463_20535	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
CE463_20545	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
CE463_20550	COG1546	Belongs to the CinA family
CE463_20555	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
CE463_20595	COG1346	cytolysis
CE463_20610	COG0460	homoserine dehydrogenase
CE463_20610	COG0527	aspartate kinase activity
CE463_20615	COG0626	cystathionine gamma-synthase activity
CE463_20630	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CE463_20635	COG0814	amino acid
CE463_20640	COG1218	3'(2'),5'-bisphosphate nucleotidase
CE463_20645	COG0494	nUDIX hydrolase
CE463_20650	COG1011	Hydrolase
CE463_20655	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
CE463_20670	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
CE463_20680	COG3156	type II secretion system protein K
CE463_20685	COG4795	General secretion pathway protein
CE463_20690	COG2165	general secretion pathway protein
CE463_20700	COG2165	general secretion pathway protein
CE463_20705	COG1459	type II secretion system
CE463_20710	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
CE463_20730	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
CE463_20735	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
CE463_20755	COG0456	acetyltransferase
CE463_20760	COG3133	Outer membrane lipoprotein
CE463_20775	COG2771	luxR family
CE463_20790	COG4776	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction
CE463_20805	COG2213	PTS system mannitol-specific
CE463_20805	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
CE463_20810	COG0246	Mannitol dehydrogenase
CE463_20815	COG3722	fumarate hydratase activity
CE463_20820	COG3263	regulation of cellular component size
CE463_20825	COG0484	heat shock protein binding
CE463_20845	COG1671	Belongs to the UPF0178 family
CE463_20860	COG1988	membrane-bound metal-dependent
CE463_20865	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
CE463_20875	COG0513	Belongs to the DEAD box helicase family
CE463_20900	COG1575	Belongs to the MenA family. Type 1 subfamily
CE463_20905	COG1169	isochorismate synthase
CE463_20910	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
CE463_20915	COG0596	Alpha beta hydrolase
CE463_20920	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
CE463_20930	COG0318	PFAM AMP-dependent synthetase and ligase
CE463_20940	COG5433	transposase activity
CE463_21005	COG5433	transposase activity
CE463_21025	COG2949	membrane
CE463_21040	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
CE463_21045	COG5380	lipid catabolic process
CE463_21060	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
CE463_21075	COG2873	o-acetylhomoserine
CE463_21105	COG4221	oxidoreductase activity
CE463_21125	COG1285	pathogenesis
CE463_21145	COG1368	sulfuric ester hydrolase activity
CE463_21150	COG1522	sequence-specific DNA binding
CE463_21160	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
CE463_21165	COG1418	mRNA catabolic process
CE463_21170	COG1058	Belongs to the CinA family
CE463_21170	COG1546	Belongs to the CinA family
CE463_21180	COG0842	Transport permease protein
CE463_21180	COG1129	ABC transporter
CE463_21205	COG0561	phosphatase activity
CE463_21210	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
CE463_21220	COG0668	transmembrane transport
CE463_21230	COG1011	Hydrolase
CE463_21245	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
CE463_21250	COG0019	diaminopimelate decarboxylase activity
CE463_21255	COG1965	Belongs to the frataxin family
CE463_21260	COG0400	carboxylic ester hydrolase activity
CE463_21265	COG3072	Adenylate cyclase
CE463_21270	COG0181	hydroxymethylbilane synthase activity
CE463_21280	COG2959	enzyme of heme biosynthesis
CE463_21295	COG1494	fructose-1,6-bisphosphatase
CE463_21345	COG3932	Exopolysaccharide synthesis, ExoD
CE463_21350	COG0814	amino acid
CE463_21355	COG5433	transposase activity
CE463_21390	COG2022	thiamine diphosphate biosynthetic process
CE463_21400	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
CE463_21405	COG0352	thiamine-phosphate diphosphorylase activity
CE463_21410	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
CE463_21510	COG3328	transposase activity
CE463_21525	COG2957	Belongs to the agmatine deiminase family
CE463_21535	COG4221	oxidoreductase activity
CE463_21550	COG1024	Enoyl-CoA hydratase
CE463_21560	COG0110	maltose O-acetyltransferase activity
CE463_21570	COG4166	transmembrane transport
CE463_21585	COG1872	DUF167
CE463_21590	COG0762	integral membrane protein
CE463_21595	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
CE463_21600	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
CE463_21615	COG3022	response to hydroperoxide
CE463_21620	COG0513	Belongs to the DEAD box helicase family
CE463_21625	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
CE463_21645	COG0735	belongs to the Fur family
CE463_21650	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CE463_21665	COG0776	regulation of translation
CE463_21670	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
CE463_21695	COG0560	Phosphoserine phosphatase
CE463_21705	COG0813	purine-nucleoside phosphorylase activity
CE463_21710	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
CE463_21715	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
CE463_21720	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
CE463_21735	COG0084	hydrolase, TatD family'
CE463_21755	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
CE463_21760	COG0004	ammonium transporteR
CE463_21795	COG0745	RESPONSE REGULATOR receiver
CE463_21805	COG0189	ligase activity
CE463_21835	COG1639	'signal transduction protein
CE463_21845	COG3700	Belongs to the class B bacterial acid phosphatase family
CE463_21855	COG1366	Belongs to the anti-sigma-factor antagonist family
CE463_21860	COG2172	sigma factor antagonist activity
CE463_21865	COG5002	protein histidine kinase activity
CE463_21865	COG2205	protein histidine kinase activity
CE463_21865	COG0784	Response regulator, receiver
CE463_21870	COG3437	response regulator, receiver
CE463_21880	COG0477	Major facilitator Superfamily
CE463_21895	COG0312	modulator of DNA gyrase
CE463_21900	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CE463_21910	COG3164	Protein of unknown function
CE463_21915	COG1530	ribonuclease E activity
CE463_21920	COG0424	maF-like protein
CE463_21925	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
CE463_21930	COG1792	Involved in formation and maintenance of cell shape
CE463_21935	COG1077	Cell shape determining protein MreB Mrl
CE463_21995	COG2200	EAL domain
CE463_21995	COG2199	diguanylate cyclase activity
CE463_22005	COG0387	Pfam Sodium calcium exchanger
CE463_22010	COG2986	histidine ammonia-lyase
CE463_22015	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
CE463_22020	COG0010	Belongs to the arginase family
CE463_22025	COG1228	amidohydrolase
CE463_22030	COG2188	Transcriptional regulator
CE463_22035	COG0288	reversible hydration of carbon dioxide
CE463_22045	COG2177	Part of the ABC transporter FtsEX involved in
CE463_22050	COG2884	Cell division ATP-binding protein ftsE
CE463_22055	COG0552	protein localization to endoplasmic reticulum
CE463_22060	COG0742	ribosomal rna small subunit methyltransferase
CE463_22085	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CE463_22090	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
CE463_22100	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CE463_22110	COG2095	MarC family integral membrane protein
CE463_22120	COG1301	dicarboxylic acid transport
CE463_22145	COG3714	YhhN family
CE463_22165	COG1770	oligopeptidase
CE463_22180	COG2249	NAD(P)H dehydrogenase (quinone) activity
CE463_22225	COG1987	bacterial-type flagellum assembly
CE463_22250	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
CE463_22255	COG3107	peptidoglycan biosynthetic process
CE463_22260	COG0792	nuclease activity
CE463_22265	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
CE463_22270	COG2823	Periplasmic or secreted lipoprotein
CE463_22275	COG2969	positive regulation of protein catabolic process
CE463_22280	COG0625	glutathione transferase activity
CE463_22285	COG2857	Cytochrome c1
CE463_22290	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
CE463_22295	COG0723	plastoquinol--plastocyanin reductase activity
CE463_22300	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
CE463_22305	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
CE463_22310	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
CE463_22320	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CE463_22325	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CE463_22360	COG3964	amidohydrolase
CE463_22380	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CE463_22385	COG1660	Displays ATPase and GTPase activities
CE463_22390	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CE463_22400	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
CE463_22405	COG1137	ATPase activity
CE463_22410	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
CE463_22415	COG3117	lipopolysaccharide transmembrane transporter activity
CE463_22420	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
CE463_22425	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
CE463_22425	COG0517	IMP dehydrogenase activity
CE463_22430	COG1127	ABC transporter
CE463_22435	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
CE463_22440	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
CE463_22445	COG2854	intermembrane phospholipid transfer
CE463_22455	COG5007	Belongs to the BolA IbaG family
CE463_22460	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
CE463_22465	COG0312	modulator of DNA gyrase
CE463_22470	COG3028	Belongs to the UPF0307 family
CE463_22480	COG2926	Belongs to the UPF0265 family
CE463_22520	COG0203	ribosomal protein L17
CE463_22525	COG0202	RNA polymerase activity
CE463_22530	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
CE463_22535	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
CE463_22540	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
CE463_22545	COG0257	Belongs to the bacterial ribosomal protein bL36 family
CE463_22550	COG0201	protein transport
CE463_22555	COG0200	Binds to the 23S rRNA
CE463_22560	COG1841	ribosomal large subunit assembly
CE463_22565	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
CE463_22570	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
CE463_22575	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
CE463_22580	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
CE463_22585	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
CE463_22590	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
CE463_22595	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
CE463_22600	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
CE463_22605	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
CE463_22610	COG0255	Belongs to the universal ribosomal protein uL29 family
CE463_22615	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
CE463_22620	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
CE463_22625	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
CE463_22630	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
CE463_22635	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
CE463_22640	COG0089	rRNA binding
CE463_22645	COG0088	Forms part of the polypeptide exit tunnel
CE463_22650	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
CE463_22655	COG0051	transcription antitermination factor activity, RNA binding
CE463_22670	COG0745	RESPONSE REGULATOR receiver
CE463_22675	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CE463_22680	COG2183	response to ionizing radiation
CE463_22700	COG0596	Alpha beta hydrolase
CE463_22705	COG1040	competence protein
CE463_22710	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
CE463_22710	COG0316	Belongs to the HesB IscA family
CE463_22715	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
CE463_22720	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
CE463_22725	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CE463_22730	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
CE463_22735	COG4942	peptidase
CE463_22745	COG1609	Transcriptional regulator
CE463_22750	COG0800	Aldolase
CE463_22755	COG0129	dihydroxy-acid dehydratase activity
CE463_22760	COG3265	gluconokinase activity
CE463_22765	COG2610	gluconate transmembrane transporter activity
CE463_22770	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CE463_22775	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
CE463_22785	COG0456	acetyltransferase
CE463_22795	COG1490	D-aminoacyl-tRNA deacylase activity
CE463_22800	COG1295	ribonuclease BN
CE463_22810	COG0174	glutamine synthetase
CE463_22820	COG3852	Histidine kinase
CE463_22825	COG2204	response regulator
CE463_22830	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
CE463_22835	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CE463_22845	COG3078	GTPase activator activity
CE463_22855	COG0218	Necessary for normal cell division and for the maintenance of normal septation
CE463_22865	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
CE463_22870	COG0408	coproporphyrinogen oxidase activity
CE463_22875	COG0009	L-threonylcarbamoyladenylate synthase
CE463_22885	COG0551	DNA topoisomerase type I activity
CE463_22890	COG2922	Belongs to the Smg family
CE463_22895	COG0758	DNA mediated transformation
CE463_22900	COG1652	LysM domain
CE463_22905	COG0242	peptide deformylase activity
CE463_22910	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
CE463_22915	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
CE463_22915	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CE463_22920	COG0569	domain protein
CE463_22925	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
CE463_22930	COG1322	Protein conserved in bacteria
CE463_22950	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CE463_22955	COG0686	Belongs to the AlaDH PNT family
CE463_22960	COG0518	GMP synthase (glutamine-hydrolyzing) activity
CE463_22960	COG0519	Catalyzes the synthesis of GMP from XMP
CE463_22980	COG1012	belongs to the aldehyde dehydrogenase family
CE463_22990	COG2962	Rard protein
CE463_23000	COG1280	lysine exporter protein (LysE YggA)
CE463_23020	COG2146	nitrite reductase [NAD(P)H] activity
CE463_23025	COG2116	formate transmembrane transporter activity
CE463_23030	COG1648	precorrin-2 dehydrogenase activity
CE463_23030	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
CE463_23035	COG2239	Acts as a magnesium transporter
CE463_23045	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
CE463_23050	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
CE463_23060	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
CE463_23070	COG0514	ATP-dependent DNA helicase (RecQ)
CE463_23075	COG2050	protein possibly involved in aromatic compounds catabolism
CE463_23095	COG2258	MOSC domain
CE463_23100	COG1177	transmembrane transport
CE463_23105	COG1176	ABC-type spermidine putrescine transport system, permease component I
CE463_23110	COG3842	ATPase activity
CE463_23130	COG0174	glutamine synthetase
CE463_23135	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
CE463_23150	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CE463_23155	COG0443	Heat shock 70 kDa protein
CE463_23170	COG0366	Alpha amylase catalytic
CE463_23175	COG1086	Polysaccharide biosynthesis protein
CE463_23180	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
CE463_23205	COG0318	PFAM AMP-dependent synthetase and ligase
CE463_23225	COG1083	cytidylyl-transferase
CE463_23235	COG2089	acid synthase
CE463_23260	COG5433	transposase activity
CE463_23270	COG4310	Domain of unknown function (DUF2172)
CE463_23305	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
CE463_23310	COG0745	RESPONSE REGULATOR receiver
CE463_23315	COG2205	protein histidine kinase activity
CE463_23325	COG0281	malic enzyme
CE463_23330	COG0702	epimerase
CE463_23335	COG0254	rRNA binding
CE463_23340	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
CE463_23350	COG1309	transcriptional regulator
CE463_23370	COG0129	dihydroxy-acid dehydratase activity
CE463_23375	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CE463_23380	COG3978	acetolactate synthase activity
CE463_23390	COG0606	chelatase, subunit chli
CE463_23400	COG1683	Conserved Protein
CE463_23410	COG1335	isochorismatase
CE463_23420	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
CE463_23425	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
CE463_23430	COG3639	organic phosphonate transmembrane transporter activity
CE463_23435	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
CE463_23440	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
CE463_23450	COG3084	Protein conserved in bacteria
CE463_23455	COG3706	GGDEF domain
CE463_23455	COG5001	Diguanylate cyclase
CE463_23455	COG4251	negative regulation of phosphorylation
CE463_23455	COG2203	Gaf domain
CE463_23470	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
CE463_23480	COG1561	YicC-like family, N-terminal region
CE463_23515	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CE463_23530	COG1063	alcohol dehydrogenase
CE463_23545	COG0210	DNA helicase
CE463_23550	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
CE463_23555	COG2166	iron-sulfur cluster assembly
CE463_23560	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
CE463_23590	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
CE463_23595	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
CE463_23600	COG1739	Uncharacterized protein family UPF0029
CE463_23610	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CE463_23615	COG1250	3-hydroxyacyl-CoA dehydrogenase
CE463_23615	COG1024	Enoyl-CoA hydratase
CE463_23620	COG0183	Belongs to the thiolase family
CE463_23625	COG0745	RESPONSE REGULATOR receiver
CE463_23630	COG2205	protein histidine kinase activity
CE463_23645	COG0425	Belongs to the sulfur carrier protein TusA family
CE463_23650	COG0251	oxidation-reduction process
CE463_23655	COG2885	chlorophyll binding
CE463_23665	COG0752	glycyl-tRNA synthetase alpha subunit
CE463_23670	COG0751	glycine-tRNA ligase activity
CE463_23690	COG2188	Transcriptional regulator
CE463_23695	COG3604	Transcriptional regulator
CE463_23705	COG0446	pyridine nucleotide-disulphide oxidoreductase
CE463_23715	COG0348	domain, Protein
CE463_23720	COG0814	amino acid
CE463_23735	COG2199	diguanylate cyclase activity
CE463_23735	COG2202	Pas domain
CE463_23735	COG2200	EAL domain
CE463_23765	COG3328	transposase activity
CE463_23795	COG1609	Transcriptional regulator
CE463_23805	COG0559	Belongs to the binding-protein-dependent transport system permease family
CE463_23835	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CE463_23860	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
CE463_23870	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
CE463_23875	COG3118	belongs to the thioredoxin family
CE463_23880	COG0513	Belongs to the DEAD box helicase family
CE463_23885	COG0248	Ppx GppA phosphatase
CE463_23895	COG0742	ribosomal rna small subunit methyltransferase
CE463_23900	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CE463_23920	COG0084	hydrolase, TatD family'
CE463_23925	COG0805	protein transport
CE463_23930	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CE463_23940	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
CE463_23945	COG3165	ubiquinone biosynthetic process from chorismate
CE463_23955	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
CE463_23960	COG0402	S-adenosylhomocysteine deaminase activity
CE463_24000	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
CE463_24005	COG0848	biopolymer transport protein
CE463_24010	COG0811	peptide transport
CE463_24015	COG0811	peptide transport
CE463_24025	COG2771	luxR family
CE463_24030	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
CE463_24035	COG1349	DNA-binding transcription factor activity
CE463_24040	COG0745	RESPONSE REGULATOR receiver
CE463_24055	COG4452	Inner membrane protein CreD
CE463_24060	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
CE463_24065	COG0355	proton-transporting ATP synthase activity, rotational mechanism
CE463_24070	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
CE463_24075	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
CE463_24080	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
CE463_24085	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
CE463_24090	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
CE463_24100	COG0356	it plays a direct role in the translocation of protons across the membrane
CE463_24105	COG3312	ion transport
CE463_24110	COG1475	DNA binding
CE463_24115	COG1192	Involved in chromosome partitioning
CE463_24120	COG0357	Ribosomal RNA small subunit methyltransferase G
CE463_24125	COG0445	tRNA wobble uridine modification
CE463_24130	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
CE463_24135	COG4774	siderophore transport
CE463_24140	COG4615	Cyclic peptide transporter
CE463_24145	COG1120	ATPase activity
CE463_24150	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CE463_24160	COG4774	siderophore transport
CE463_24165	COG4607	ABC-type enterochelin transport system periplasmic component
CE463_24170	COG4604	ABC transporter, ATP-binding protein
CE463_24175	COG4605	iron ion homeostasis
CE463_24180	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CE463_24200	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CE463_24210	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CE463_24225	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
CE463_24230	COG0706	membrane insertase activity
CE463_24235	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
CE463_24240	COG0594	ribonuclease P activity
CE463_24245	COG0230	Belongs to the bacterial ribosomal protein bL34 family