locus-tag	class	description
G7042_00120	COG4695	Portal protein
G7042_00165	COG2176	DNA-directed DNA polymerase activity
G7042_00165	COG5002	protein histidine kinase activity
G7042_00255	COG4974	Belongs to the 'phage' integrase family
G7042_00260	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
G7042_00265	COG1073	alpha beta
G7042_00275	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
G7042_00280	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
G7042_00310	COG1522	sequence-specific DNA binding
G7042_00310	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
G7042_00315	COG2313	pseudouridylate synthase activity
G7042_00325	COG5433	transposase activity
G7042_00330	COG1858	cytochrome C peroxidase
G7042_00375	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
G7042_00380	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
G7042_00390	COG0318	PFAM AMP-dependent synthetase and ligase
G7042_00405	COG2986	histidine ammonia-lyase
G7042_00430	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
G7042_00440	COG1028	Short-chain dehydrogenase reductase Sdr
G7042_00445	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
G7042_00455	COG0521	Mo-molybdopterin cofactor biosynthetic process
G7042_00470	COG2966	Psort location CytoplasmicMembrane, score
G7042_00475	COG3610	response to peptide
G7042_00485	COG4175	Glycine betaine
G7042_00490	COG4176	ABC-type proline glycine betaine transport system permease component
G7042_00495	COG2113	Glycine betaine
G7042_00500	COG0175	sulfate reduction
G7042_00505	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
G7042_00510	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
G7042_00515	COG0384	phenazine biosynthesis protein PhzF
G7042_00520	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
G7042_00535	COG0786	glutamate:sodium symporter activity
G7042_00540	COG0252	asparaginase activity
G7042_00545	COG3139	Protein of unknown function (DUF1315)
G7042_00565	COG0616	signal peptide processing
G7042_00570	COG0446	pyridine nucleotide-disulphide oxidoreductase
G7042_00570	COG1902	pentaerythritol trinitrate reductase activity
G7042_00575	COG0778	Nitroreductase
G7042_00595	COG4302	ethanolamine ammonia-lyase activity
G7042_00600	COG4303	Ethanolamine ammonia lyase large subunit
G7042_00605	COG0531	amino acid
G7042_00610	COG2264	protein methyltransferase activity
G7042_00615	COG0604	alcohol dehydrogenase
G7042_00620	COG0583	DNA-binding transcription factor activity
G7042_00625	COG2190	(PTS) system
G7042_00625	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
G7042_00625	COG1263	PTS System
G7042_00630	COG4145	pantothenate transmembrane transporter activity
G7042_00635	COG3924	membrane
G7042_00640	COG0439	Biotin carboxylase
G7042_00645	COG0511	ligase activity, forming carbon-carbon bonds
G7042_00650	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
G7042_00655	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
G7042_00685	COG3381	protein complex oligomerization
G7042_00700	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
G7042_00715	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
G7042_00720	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
G7042_00720	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
G7042_00735	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
G7042_00740	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
G7042_00745	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
G7042_00750	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
G7042_00755	COG4172	Belongs to the ABC transporter superfamily
G7042_00765	COG0601	transmembrane transport
G7042_00775	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
G7042_00780	COG0142	geranyltranstransferase activity
G7042_00785	COG1722	exodeoxyribonuclease VII activity
G7042_00790	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
G7042_00795	COG1360	Flagellar Motor Protein
G7042_00825	COG1534	Rna-binding protein
G7042_00830	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
G7042_00840	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
G7042_00845	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
G7042_00850	COG0149	triose-phosphate isomerase activity
G7042_00855	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
G7042_00870	COG0779	Required for maturation of 30S ribosomal subunits
G7042_00875	COG0195	Participates in both transcription termination and antitermination
G7042_00880	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
G7042_00885	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
G7042_00890	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
G7042_00895	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
G7042_00900	COG1185	polyribonucleotide nucleotidyltransferase activity
G7042_00905	COG2211	Major facilitator Superfamily
G7042_00910	COG3706	GGDEF domain
G7042_00915	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
G7042_00920	COG1422	Protein of unknown function (DUF1090)
G7042_00935	COG5433	transposase activity
G7042_00980	COG0312	modulator of DNA gyrase
G7042_00995	COG4974	Belongs to the 'phage' integrase family
G7042_01005	COG1970	mechanosensitive ion channel activity
G7042_01015	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
G7042_01030	COG3545	Serine hydrolase
G7042_01035	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
G7042_01055	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
G7042_01060	COG0321	lipoyl(octanoyl) transferase activity
G7042_01065	COG2921	Belongs to the UPF0250 family
G7042_01070	COG1686	Belongs to the peptidase S11 family
G7042_01075	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
G7042_01080	COG2951	lytic endotransglycosylase activity
G7042_01085	COG0772	Belongs to the SEDS family
G7042_01090	COG0768	penicillin binding
G7042_01095	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
G7042_01100	COG0799	negative regulation of ribosome biogenesis
G7042_01105	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
G7042_01125	COG0495	leucyl-tRNA aminoacylation
G7042_01130	COG2888	peptidyl-tyrosine sulfation
G7042_01135	COG0815	Transfers the fatty acyl group on membrane lipoproteins
G7042_01140	COG4535	Mg2 and Co2 transporter CorC
G7042_01145	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
G7042_01150	COG1702	phosphate starvation-inducible protein PhoH
G7042_01155	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
G7042_01160	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
G7042_01170	COG3706	GGDEF domain
G7042_01185	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
G7042_01205	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
G7042_01215	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
G7042_01225	COG0516	GMP reductase activity
G7042_01235	COG0642	Histidine kinase
G7042_01275	COG3214	Protein conserved in bacteria
G7042_01295	COG3080	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
G7042_01300	COG3029	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
G7042_01305	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
G7042_01310	COG1053	succinate dehydrogenase
G7042_01320	COG0584	glycerophosphoryl diester phosphodiesterase
G7042_01350	COG0739	heme binding
G7042_01365	COG0583	DNA-binding transcription factor activity
G7042_01380	COG0840	transmembrane signaling receptor activity
G7042_01385	COG0583	DNA-binding transcription factor activity
G7042_01390	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
G7042_01420	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
G7042_01425	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
G7042_01435	COG0338	D12 class N6 adenine-specific DNA methyltransferase
G7042_01440	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
G7042_01445	COG0546	phosphoglycolate phosphatase activity
G7042_01450	COG0180	Tryptophanyl-tRNA synthetase
G7042_01465	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
G7042_01475	COG1012	belongs to the aldehyde dehydrogenase family
G7042_01485	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
G7042_01505	COG0488	(ABC) transporter
G7042_01515	COG0366	Alpha amylase catalytic
G7042_01530	COG0443	Heat shock 70 kDa protein
G7042_01565	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
G7042_01575	COG0471	metal ion transport
G7042_01575	COG0490	domain, Protein
G7042_01620	COG0012	GTP binding
G7042_01625	COG0193	aminoacyl-tRNA hydrolase activity
G7042_01630	COG0737	Belongs to the 5'-nucleotidase family
G7042_01635	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
G7042_01645	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
G7042_01650	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
G7042_01655	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
G7042_01660	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
G7042_01665	COG2890	protein-(glutamine-N5) methyltransferase activity
G7042_01675	COG2912	Transglutaminase-like superfamily
G7042_01710	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
G7042_01725	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
G7042_01730	COG1115	amino acid carrier protein
G7042_01745	COG0714	Associated with various cellular activities
G7042_01765	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
G7042_01770	COG1678	Uncharacterized ACR, COG1678
G7042_01790	COG0189	ligase activity
G7042_01795	COG1385	rRNA (uridine-N3-)-methyltransferase activity
G7042_01805	COG3091	SprT-like family
G7042_01815	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
G7042_01820	COG5433	transposase activity
G7042_01840	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
G7042_01845	COG0739	heme binding
G7042_01850	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
G7042_01870	COG0463	Glycosyl transferase, family 2
G7042_01885	COG2989	Protein conserved in bacteria
G7042_01890	COG3108	Peptidase M15
G7042_01900	COG2860	membrane
G7042_01910	COG1196	nuclear chromosome segregation
G7042_01915	COG3115	cell septum assembly
G7042_01920	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
G7042_01930	COG1328	CTP reductase activity
G7042_01940	COG0602	queuosine metabolic process
G7042_01965	COG1566	PFAM secretion protein HlyD family protein
G7042_01970	COG1846	Transcriptional regulator
G7042_01985	COG0582	viral genome integration into host DNA
G7042_01990	COG1196	nuclear chromosome segregation
G7042_01990	COG3264	Mechanosensitive ion channel
G7042_01995	COG0469	pyruvate kinase activity
G7042_02010	COG4651	solute:proton antiporter activity
G7042_02010	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
G7042_02015	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
G7042_02015	COG4651	solute:proton antiporter activity
G7042_02020	COG0405	Gamma-glutamyltransferase
G7042_02025	COG2974	May be involved in recombination
G7042_02035	COG0420	3'-5' exonuclease activity
G7042_02040	COG0419	ATPase involved in DNA repair
G7042_02050	COG5433	transposase activity
G7042_02060	COG3038	cytochrome b561
G7042_02075	COG2190	(PTS) system
G7042_02085	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
G7042_02090	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
G7042_02110	COG1720	tRNA m6t6A37 methyltransferase activity
G7042_02130	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
G7042_02135	COG4988	ABC transporter
G7042_02150	COG0745	RESPONSE REGULATOR receiver
G7042_02160	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
G7042_02175	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
G7042_02180	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
G7042_02190	COG0083	homoserine kinase activity
G7042_02195	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
G7042_02230	COG0813	purine-nucleoside phosphorylase activity
G7042_02245	COG3384	dioxygenase
G7042_02255	COG1283	sodium-dependent phosphate transmembrane transporter activity
G7042_02260	COG0531	amino acid
G7042_02265	COG0531	amino acid
G7042_02280	COG1917	Cupin 2, conserved barrel domain protein
G7042_02280	COG1396	sequence-specific DNA binding
G7042_02285	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
G7042_02300	COG1917	Cupin 2, conserved barrel domain protein
G7042_02300	COG2169	Transcriptional regulator
G7042_02305	COG5433	transposase activity
G7042_02335	COG0840	transmembrane signaling receptor activity
G7042_02340	COG0835	chemotaxis
G7042_02360	COG0745	RESPONSE REGULATOR receiver
G7042_02365	COG0840	transmembrane signaling receptor activity
G7042_02370	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
G7042_02380	COG1280	lysine exporter protein (LysE YggA)
G7042_02395	COG3813	Protein conserved in bacteria
G7042_02405	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
G7042_02420	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
G7042_02445	COG0300	oxidoreductase activity
G7042_02475	COG2133	pyrroloquinoline quinone binding
G7042_02500	COG1605	Chorismate mutase
G7042_02500	COG0077	Prephenate dehydratase
G7042_02530	COG3272	Protein of unknown function (DUF1722)
G7042_02535	COG0789	Transcriptional regulator
G7042_02540	COG0415	Belongs to the DNA photolyase family
G7042_02550	COG0300	oxidoreductase activity
G7042_02565	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
G7042_02590	COG0783	Belongs to the Dps family
G7042_02595	COG1151	hydroxylamine reductase activity
G7042_02605	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
G7042_02610	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
G7042_02610	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
G7042_02620	COG3459	Glycosyltransferase 36 associated
G7042_02640	COG0693	protein deglycase activity
G7042_02645	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
G7042_02650	COG1666	GTP binding
G7042_02655	COG3248	Nucleoside-binding outer membrane protein
G7042_02660	COG2211	Major facilitator Superfamily
G7042_02670	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
G7042_02680	COG2813	Specifically methylates the guanine in position
G7042_02685	COG0271	Belongs to the BolA IbaG family
G7042_02695	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
G7042_02700	COG1805	sodium ion transport
G7042_02705	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
G7042_02710	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
G7042_02715	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
G7042_02720	COG2871	sodium ion transport
G7042_02725	COG1477	protein flavinylation
G7042_02740	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
G7042_02745	COG0840	transmembrane signaling receptor activity
G7042_02750	COG0583	DNA-binding transcription factor activity
G7042_02760	COG2363	Small membrane protein
G7042_02765	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
G7042_02775	COG0473	3-isopropylmalate dehydrogenase activity
G7042_02780	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
G7042_02785	COG1611	Belongs to the LOG family
G7042_02800	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
G7042_02800	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
G7042_02810	COG5595	Zn-ribbon-containing, possibly nucleic-acid-binding protein (DUF2310)
G7042_02835	COG3098	single-species biofilm formation
G7042_02840	COG0564	pseudouridine synthase activity
G7042_02850	COG5433	transposase activity
G7042_02855	COG4580	involved in the transport of maltose and maltodextrins
G7042_02865	COG1263	PTS System
G7042_02865	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
G7042_02875	COG2171	N-acyltransferase activity
G7042_02880	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
G7042_02885	COG0024	Methionine aminopeptidase
G7042_02890	COG0052	Belongs to the universal ribosomal protein uS2 family
G7042_02895	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
G7042_02900	COG0528	UMP kinase activity
G7042_02905	COG0233	cytoplasmic translational termination
G7042_02910	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
G7042_02915	COG0575	Belongs to the CDS family
G7042_02920	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
G7042_02925	COG0750	zinc metalloprotease
G7042_02940	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
G7042_02945	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
G7042_02950	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
G7042_02955	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
G7042_02960	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
G7042_02970	COG0825	malonyl-CoA metabolic process
G7042_02975	COG3710	Transcriptional regulator
G7042_02980	COG0531	amino acid
G7042_02985	COG1982	Orn Lys Arg decarboxylase major
G7042_02990	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
G7042_03005	COG0814	amino acid
G7042_03010	COG0531	amino acid
G7042_03020	COG0488	(ABC) transporter
G7042_03030	COG3590	peptidase
G7042_03035	COG0037	tRNA processing
G7042_03080	COG0366	Alpha amylase catalytic
G7042_03090	COG1881	PFAM PEBP family protein
G7042_03095	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
G7042_03100	COG0583	DNA-binding transcription factor activity
G7042_03110	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
G7042_03120	COG0583	DNA-binding transcription factor activity
G7042_03125	COG1028	Short-chain dehydrogenase reductase Sdr
G7042_03130	COG0616	signal peptide processing
G7042_03135	COG3724	N-succinylarginine dihydrolase activity
G7042_03155	COG0840	transmembrane signaling receptor activity
G7042_03165	COG2971	BadF BadG BcrA BcrD
G7042_03175	COG4608	Belongs to the ABC transporter superfamily
G7042_03180	COG0444	Belongs to the ABC transporter superfamily
G7042_03185	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
G7042_03235	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
G7042_03240	COG1289	transmembrane transporter activity
G7042_03245	COG0303	'Molybdopterin
G7042_03250	COG0746	molybdenum cofactor guanylyltransferase activity
G7042_03260	COG4662	Binding-protein-dependent transport system inner membrane component
G7042_03275	COG3852	Histidine kinase
G7042_03285	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
G7042_03300	COG5433	transposase activity
G7042_03330	COG3383	formate dehydrogenase (NAD+) activity
G7042_03335	COG0437	4 iron, 4 sulfur cluster binding
G7042_03350	COG0281	malic enzyme
G7042_03360	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
G7042_03380	COG0281	malic enzyme
G7042_03385	COG3290	protein histidine kinase activity
G7042_03400	COG0667	Aldo Keto reductase
G7042_03410	COG0697	spore germination
G7042_03430	COG2267	carboxylic ester hydrolase activity
G7042_03435	COG1942	4-Oxalocrotonate Tautomerase
G7042_03445	COG3284	Transcriptional regulator
G7042_03450	COG3706	GGDEF domain
G7042_03455	COG0346	lactoylglutathione lyase activity
G7042_03460	COG0745	RESPONSE REGULATOR receiver
G7042_03465	COG5002	protein histidine kinase activity
G7042_03485	COG1940	carbohydrate kinase activity
G7042_03490	COG3142	Participates in the control of copper homeostasis
G7042_03495	COG0545	Peptidyl-prolyl cis-trans isomerase
G7042_03500	COG1131	(ABC) transporter
G7042_03540	COG0019	diaminopimelate decarboxylase activity
G7042_03545	COG1115	amino acid carrier protein
G7042_03550	COG0095	Lipoate-protein ligase
G7042_03555	COG2233	PERMEase
G7042_03570	COG0534	Mate efflux family protein
G7042_03575	COG2207	Transcriptional regulator
G7042_03580	COG0281	malic enzyme
G7042_03615	COG0733	neurotransmitter:sodium symporter activity
G7042_03620	COG1752	Esterase of the alpha-beta hydrolase superfamily
G7042_03625	COG3706	GGDEF domain
G7042_03630	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
G7042_03635	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
G7042_03645	COG1032	radical SAM domain protein
G7042_03665	COG5433	transposase activity
G7042_03680	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
G7042_03685	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
G7042_03690	COG1196	nuclear chromosome segregation
G7042_03690	COG0741	lytic transglycosylase activity
G7042_03690	COG0739	heme binding
G7042_03695	COG0366	Alpha amylase catalytic
G7042_03715	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
G7042_03725	COG0788	formyltetrahydrofolate deformylase activity
G7042_03730	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
G7042_03740	COG3118	belongs to the thioredoxin family
G7042_03745	COG2091	lysine biosynthetic process via aminoadipic acid
G7042_03750	COG0791	NLP P60 protein
G7042_03755	COG3129	Specifically methylates the adenine in position 1618 of 23S rRNA
G7042_03770	COG1388	LysM domain
G7042_03770	COG1376	ErfK ybiS ycfS ynhG family protein
G7042_03820	COG1960	acyl-CoA dehydrogenase activity
G7042_03825	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
G7042_03835	COG0469	pyruvate kinase activity
G7042_03840	COG1737	Transcriptional regulator
G7042_03865	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
G7042_03885	COG1342	Belongs to the UPF0251 family
G7042_03940	COG1684	flagellar biosynthetic protein fliR
G7042_03950	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
G7042_03975	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
G7042_03985	COG0450	alkyl hydroperoxide reductase
G7042_04005	COG0500	methyltransferase
G7042_04010	COG4106	trans-aconitate 2-methyltransferase activity
G7042_04030	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
G7042_04035	COG0217	transcriptional regulatory protein
G7042_04105	COG1846	Transcriptional regulator
G7042_04105	COG1940	carbohydrate kinase activity
G7042_04110	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
G7042_04115	COG0363	glucosamine-6-phosphate deaminase activity
G7042_04135	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
G7042_04140	COG0735	belongs to the Fur family
G7042_04150	COG0716	FMN binding
G7042_04165	COG0596	Alpha beta hydrolase
G7042_04170	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
G7042_04175	COG0033	Phosphoglucomutase
G7042_04185	COG1846	Transcriptional regulator
G7042_04190	COG2951	lytic endotransglycosylase activity
G7042_04195	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
G7042_04200	COG4136	ATPase activity
G7042_04205	COG4135	transport system, permease component
G7042_04210	COG4134	Bacterial extracellular solute-binding protein
G7042_04215	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
G7042_04220	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
G7042_04230	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
G7042_04235	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
G7042_04250	COG0729	surface antigen
G7042_04255	COG2911	Protein conserved in bacteria
G7042_04270	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
G7042_04295	COG1607	acyl-coa hydrolase
G7042_04300	COG3021	interspecies interaction between organisms
G7042_04305	COG1388	LysM domain
G7042_04305	COG0741	lytic transglycosylase activity
G7042_04310	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
G7042_04315	COG2226	methyltransferase
G7042_04320	COG0328	RNA-DNA hybrid ribonuclease activity
G7042_04325	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
G7042_04335	COG0784	Response regulator, receiver
G7042_04335	COG3437	response regulator, receiver
G7042_04340	COG1960	acyl-CoA dehydrogenase activity
G7042_04345	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
G7042_04350	COG0121	glutamine amidotransferase
G7042_04380	COG2197	response regulator
G7042_04385	COG3850	Histidine kinase
G7042_04390	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
G7042_04395	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
G7042_04405	COG0243	molybdopterin cofactor binding
G7042_04410	COG0437	4 iron, 4 sulfur cluster binding
G7042_04415	COG0348	domain, Protein
G7042_04425	COG3005	denitrification pathway
G7042_04430	COG0521	Mo-molybdopterin cofactor biosynthetic process
G7042_04435	COG0315	cyclic pyranopterin monophosphate synthase activity
G7042_04440	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
G7042_04445	COG0314	molybdopterin synthase activity
G7042_04460	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
G7042_04465	COG0596	Alpha beta hydrolase
G7042_04490	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
G7042_04500	COG0302	gtp cyclohydrolase
G7042_04505	COG0840	transmembrane signaling receptor activity
G7042_04510	COG2759	Belongs to the formate--tetrahydrofolate ligase family
G7042_04520	COG0583	DNA-binding transcription factor activity
G7042_04525	COG2353	YceI-like domain
G7042_04550	COG2195	Cleaves the N-terminal amino acid of tripeptides
G7042_04560	COG1166	arginine decarboxylase activity
G7042_04575	COG0346	lactoylglutathione lyase activity
G7042_04585	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
G7042_04590	COG1187	pseudouridine synthase activity
G7042_04595	COG2807	transmembrane transport
G7042_04605	COG0583	DNA-binding transcription factor activity
G7042_04625	COG2979	Protein of unknown function (DUF533)
G7042_04630	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
G7042_04660	COG2814	Major facilitator Superfamily
G7042_04665	COG0656	L-ascorbic acid biosynthetic process
G7042_04670	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
G7042_04695	COG0583	DNA-binding transcription factor activity
G7042_04700	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
G7042_04705	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
G7042_04710	COG2271	Major facilitator Superfamily
G7042_04715	COG1349	DNA-binding transcription factor activity
G7042_04725	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
G7042_04730	COG0584	glycerophosphoryl diester phosphodiesterase
G7042_04735	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
G7042_04740	COG0287	Prephenate dehydrogenase
G7042_04740	COG1605	Chorismate mutase
G7042_04745	COG0583	DNA-binding transcription factor activity
G7042_04750	COG3085	chromosome segregation
G7042_04755	COG4574	serine-type endopeptidase inhibitor activity
G7042_04775	COG1770	oligopeptidase
G7042_04795	COG3083	sulfuric ester hydrolase activity
G7042_04800	COG3082	Protein of unknown function (DUF1414)
G7042_04805	COG3081	Nucleoid-associated protein
G7042_04810	COG2182	Extracellular solute-binding protein
G7042_04820	COG3833	ABC-type maltose transport systems, permease component
G7042_04825	COG3842	ATPase activity
G7042_04840	COG0628	permease
G7042_04845	COG0425	Belongs to the sulfur carrier protein TusA family
G7042_04850	COG4783	chaperone-mediated protein folding
G7042_04860	COG1393	Belongs to the ArsC family
G7042_04870	COG3124	Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP
G7042_04875	COG2431	L-lysine efflux transmembrane transporter activity
G7042_04910	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
G7042_04920	COG0446	pyridine nucleotide-disulphide oxidoreductase
G7042_04925	COG2373	Large extracellular alpha-helical protein
G7042_04930	COG4953	penicillin-binding protein 1C
G7042_04940	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
G7042_04940	COG0301	tRNA thio-modification
G7042_04955	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
G7042_04985	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
G7042_04995	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
G7042_05015	COG0483	inositol monophosphate 1-phosphatase activity
G7042_05025	COG0625	glutathione transferase activity
G7042_05035	COG0601	transmembrane transport
G7042_05040	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
G7042_05045	COG0444	Belongs to the ABC transporter superfamily
G7042_05050	COG2814	Major facilitator Superfamily
G7042_05055	COG0583	DNA-binding transcription factor activity
G7042_05060	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
G7042_05065	COG0243	molybdopterin cofactor binding
G7042_05085	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
G7042_05090	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
G7042_05095	COG0404	The glycine cleavage system catalyzes the degradation of glycine
G7042_05100	COG0509	glycine decarboxylation via glycine cleavage system
G7042_05105	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
G7042_05105	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
G7042_05120	COG3634	alkyl hydroperoxide reductase activity
G7042_05130	COG0517	IMP dehydrogenase activity
G7042_05135	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
G7042_05140	COG0343	queuine tRNA-ribosyltransferase activity
G7042_05145	COG1862	Preprotein translocase
G7042_05150	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
G7042_05155	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
G7042_05160	COG2897	thiosulfate sulfurtransferase activity
G7042_05170	COG0826	peptidase U32
G7042_05175	COG0826	peptidase U32
G7042_05180	COG3154	lipid carrier protein
G7042_05195	COG1959	2 iron, 2 sulfur cluster binding
G7042_05200	COG1104	cysteine desulfurase activity
G7042_05205	COG0822	iron-sulfur transferase activity
G7042_05215	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
G7042_05220	COG0443	Heat shock 70 kDa protein
G7042_05225	COG0633	Ferredoxin
G7042_05235	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
G7042_05240	COG0105	UTP biosynthetic process
G7042_05245	COG0820	rRNA (adenine-C2-)-methyltransferase activity
G7042_05255	COG1426	Protein conserved in bacteria
G7042_05260	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
G7042_05265	COG0124	histidyl-tRNA synthetase
G7042_05270	COG2976	Protein conserved in bacteria
G7042_05275	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
G7042_05280	COG1160	GTP binding
G7042_05285	COG1645	bacterial-type flagellum-dependent swarming motility
G7042_05295	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
G7042_05300	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
G7042_05300	COG0047	phosphoribosylformylglycinamidine synthase activity
G7042_05310	COG2354	Protein conserved in bacteria
G7042_05325	COG5433	transposase activity
G7042_05350	COG1242	4 iron, 4 sulfur cluster binding
G7042_05430	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
G7042_05435	COG1288	antiporter activity
G7042_05440	COG0436	Aminotransferase
G7042_05450	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
G7042_05455	COG2027	D-alanyl-D-alanine carboxypeptidase
G7042_05460	COG1061	Type III restriction enzyme res subunit
G7042_05465	COG1566	PFAM secretion protein HlyD family protein
G7042_05475	COG1966	Carbon starvation protein
G7042_05480	COG3279	Response regulator of the LytR AlgR family
G7042_05485	COG3275	phosphorelay sensor kinase activity
G7042_05505	COG1454	alcohol dehydrogenase
G7042_05505	COG1012	belongs to the aldehyde dehydrogenase family
G7042_05515	COG2095	MarC family integral membrane protein
G7042_05525	COG0601	transmembrane transport
G7042_05530	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
G7042_05535	COG0444	Belongs to the ABC transporter superfamily
G7042_05550	COG0861	Integral membrane protein TerC family
G7042_05555	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
G7042_05565	COG1301	dicarboxylic acid transport
G7042_05580	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
G7042_05595	COG0537	adenosine 5'-monophosphoramidase activity
G7042_05630	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
G7042_05635	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
G7042_05655	COG5433	transposase activity
G7042_05670	COG1007	ATP synthesis coupled electron transport
G7042_05675	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
G7042_05685	COG0713	ATP synthesis coupled electron transport
G7042_05690	COG0839	Belongs to the complex I subunit 6 family
G7042_05695	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
G7042_05700	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
G7042_05705	COG1034	ATP synthesis coupled electron transport
G7042_05720	COG0649	NAD binding
G7042_05720	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
G7042_05725	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
G7042_05730	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
G7042_05735	COG1360	Flagellar Motor Protein
G7042_05755	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
G7042_05770	COG4597	amino acid ABC transporter
G7042_05775	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
G7042_05780	COG0765	amino acid transport
G7042_05785	COG1126	abc transporter atp-binding protein
G7042_05795	COG0724	RNA recognition motif
G7042_05800	COG4989	oxidoreductase activity
G7042_05830	COG0583	DNA-binding transcription factor activity
G7042_05845	COG3300	MHYT domain
G7042_05845	COG5001	Diguanylate cyclase
G7042_05865	COG2814	Major facilitator Superfamily
G7042_05880	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
G7042_05885	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
G7042_05890	COG0539	negative regulation of cytoplasmic translation
G7042_05895	COG0776	regulation of translation
G7042_05905	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
G7042_05910	COG0284	orotidine-5'-phosphate decarboxylase activity
G7042_05925	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
G7042_05930	COG0602	queuosine metabolic process
G7042_05935	COG3530	Putative quorum-sensing-regulated virulence factor
G7042_05940	COG2096	Adenosyltransferase
G7042_05945	COG2916	Histone family protein nucleoid-structuring protein H-NS
G7042_05960	COG1757	Na H antiporter
G7042_05965	COG1435	thymidine kinase activity
G7042_05985	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
G7042_06000	COG5433	transposase activity
G7042_06010	COG0437	4 iron, 4 sulfur cluster binding
G7042_06015	COG5557	Pfam Polysulphide reductase, NrfD
G7042_06020	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
G7042_06025	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
G7042_06030	COG1773	rubredoxin
G7042_06040	COG0601	transmembrane transport
G7042_06045	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
G7042_06060	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
G7042_06065	COG0375	protein maturation
G7042_06070	COG0309	Hydrogenase expression formation protein (HypE)
G7042_06080	COG0298	carbon dioxide binding
G7042_06085	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
G7042_06095	COG1921	L-seryl-tRNASec selenium transferase activity
G7042_06105	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
G7042_06115	COG3260	NADH ubiquinone oxidoreductase 20
G7042_06120	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
G7042_06125	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
G7042_06125	COG3261	NADH dehydrogenase
G7042_06130	COG0650	Formate hydrogenlyase subunit 4
G7042_06135	COG0651	ATP synthesis coupled electron transport
G7042_06140	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
G7042_06195	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
G7042_06200	COG0326	Molecular chaperone. Has ATPase activity
G7042_06205	COG0563	adenylate kinase activity
G7042_06210	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
G7042_06215	COG3788	relative of glutathione S-transferase, MAPEG superfamily
G7042_06220	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
G7042_06225	COG0840	transmembrane signaling receptor activity
G7042_06280	COG1021	2,3-dihydroxybenzoate-AMP ligase
G7042_06285	COG3433	isochorismatase activity
G7042_06285	COG1535	isochorismatase
G7042_06290	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
G7042_06295	COG1028	Short-chain dehydrogenase reductase Sdr
G7042_06305	COG3321	synthase
G7042_06305	COG0300	oxidoreductase activity
G7042_06305	COG1028	Short-chain dehydrogenase reductase Sdr
G7042_06305	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
G7042_06305	COG0318	PFAM AMP-dependent synthetase and ligase
G7042_06310	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
G7042_06315	COG2977	Belongs to the P-Pant transferase superfamily
G7042_06320	COG1120	ATPase activity
G7042_06325	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
G7042_06330	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
G7042_06335	COG4771	TonB-dependent receptor
G7042_06360	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
G7042_06360	COG0644	oxidoreductase
G7042_06380	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
G7042_06385	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
G7042_06390	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
G7042_06405	COG1570	exodeoxyribonuclease VII activity
G7042_06425	COG5433	transposase activity
G7042_06450	COG0517	IMP dehydrogenase activity
G7042_06450	COG0516	GMP reductase activity
G7042_06455	COG0518	GMP synthase (glutamine-hydrolyzing) activity
G7042_06455	COG0519	Catalyzes the synthesis of GMP from XMP
G7042_06515	COG2062	phosphohistidine phosphatase, SixA
G7042_06525	COG0697	spore germination
G7042_06530	COG4166	transmembrane transport
G7042_06535	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
G7042_06540	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
G7042_06550	COG4591	ABC-type transport system involved in lipoprotein release permease component
G7042_06555	COG1136	(ABC) transporter
G7042_06560	COG4591	ABC-type transport system involved in lipoprotein release permease component
G7042_06565	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
G7042_06575	COG0544	peptidyl-prolyl cis-trans isomerase activity
G7042_06580	COG0740	serine-type endopeptidase activity
G7042_06585	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
G7042_06590	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
G7042_06595	COG0776	regulation of translation
G7042_06600	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
G7042_06605	COG0488	(ABC) transporter
G7042_06610	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
G7042_06615	COG3162	membrane
G7042_06630	COG1024	Enoyl-CoA hydratase
G7042_06630	COG1250	3-hydroxyacyl-CoA dehydrogenase
G7042_06635	COG1115	amino acid carrier protein
G7042_06640	COG0456	acetyltransferase
G7042_06650	COG1584	GPR1 FUN34 yaaH family protein
G7042_06680	COG1024	Enoyl-CoA hydratase
G7042_06685	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
G7042_06710	COG1960	acyl-CoA dehydrogenase activity
G7042_06715	COG1024	Enoyl-CoA hydratase
G7042_06720	COG1024	Enoyl-CoA hydratase
G7042_06730	COG1028	Short-chain dehydrogenase reductase Sdr
G7042_06740	COG0730	response to heat
G7042_06770	COG2378	regulation of single-species biofilm formation
G7042_06780	COG0140	phosphoribosyl-ATP diphosphatase activity
G7042_06780	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
G7042_06785	COG0107	imidazoleglycerol-phosphate synthase activity
G7042_06790	COG2198	Histidine kinase
G7042_06790	COG0784	Response regulator, receiver
G7042_06790	COG2205	protein histidine kinase activity
G7042_06795	COG2199	diguanylate cyclase activity
G7042_06800	COG3437	response regulator, receiver
G7042_06805	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
G7042_06810	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
G7042_06815	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
G7042_06815	COG0131	Imidazoleglycerol-phosphate dehydratase
G7042_06820	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
G7042_06825	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
G7042_06830	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
G7042_06840	COG1199	ATP-dependent helicase activity
G7042_06845	COG1214	PFAM Peptidase M22, glycoprotease
G7042_06855	COG2267	carboxylic ester hydrolase activity
G7042_06860	COG0318	PFAM AMP-dependent synthetase and ligase
G7042_06880	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
G7042_06885	COG2832	Protein of unknown function (DUF454)
G7042_06890	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
G7042_06895	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
G7042_06900	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
G7042_06905	COG3314	Sporulation integral membrane protein YlbJ
G7042_06910	COG2197	response regulator
G7042_06915	COG0517	IMP dehydrogenase activity
G7042_06915	COG0617	tRNA 3'-terminal CCA addition
G7042_06915	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
G7042_06920	COG1643	Atp-dependent helicase
G7042_06930	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
G7042_06935	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
G7042_06940	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
G7042_06945	COG0709	Synthesizes selenophosphate from selenide and ATP
G7042_06960	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
G7042_06970	COG1254	Belongs to the acylphosphatase family
G7042_06975	COG0625	glutathione transferase activity
G7042_06980	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
G7042_06980	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
G7042_06985	COG0489	protein tyrosine kinase activity
G7042_06990	COG0572	uridine kinase
G7042_06995	COG0717	Belongs to the dCTP deaminase family
G7042_07000	COG0306	phosphate transporter
G7042_07005	COG1530	ribonuclease E activity
G7042_07015	COG0546	phosphoglycolate phosphatase activity
G7042_07025	COG1399	metal-binding, possibly nucleic acid-binding protein
G7042_07030	COG0333	Belongs to the bacterial ribosomal protein bL32 family
G7042_07035	COG0416	fatty acid biosynthetic process
G7042_07040	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
G7042_07050	COG1028	Short-chain dehydrogenase reductase Sdr
G7042_07055	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
G7042_07060	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
G7042_07065	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
G7042_07070	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
G7042_07075	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
G7042_07080	COG0470	DNA polymerase III
G7042_07085	COG0084	hydrolase, TatD family'
G7042_07100	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
G7042_07100	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
G7042_07110	COG2995	paraquat-inducible protein a
G7042_07120	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
G7042_07125	COG0372	Belongs to the citrate synthase family
G7042_07170	COG4221	oxidoreductase activity
G7042_07200	COG3620	sequence-specific DNA binding
G7042_07260	COG5433	transposase activity
G7042_07440	COG0741	lytic transglycosylase activity
G7042_07475	COG2003	Belongs to the UPF0758 family
G7042_07570	COG1067	ATP-dependent peptidase activity
G7042_07575	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
G7042_07590	COG0488	(ABC) transporter
G7042_07600	COG0116	Belongs to the methyltransferase superfamily
G7042_07600	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
G7042_07615	COG0167	dihydroorotate dehydrogenase activity
G7042_07625	COG5433	transposase activity
G7042_07640	COG0308	aminopeptidase N
G7042_07650	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
G7042_07655	COG1956	GAF domain-containing protein
G7042_07665	COG3278	Belongs to the heme-copper respiratory oxidase family
G7042_07680	COG2010	Cytochrome c
G7042_07690	COG2217	Heavy metal translocating P-type atpase
G7042_07705	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
G7042_07710	COG0589	response to stress
G7042_07715	COG0037	tRNA processing
G7042_07735	COG1869	D-ribose catabolic process
G7042_07745	COG1172	Belongs to the binding-protein-dependent transport system permease family
G7042_07750	COG1879	ABC-type sugar transport system periplasmic component
G7042_07755	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
G7042_07760	COG1609	Transcriptional regulator
G7042_07805	COG0776	regulation of translation
G7042_07810	COG0072	phenylalanine-tRNA ligase activity
G7042_07810	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
G7042_07815	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
G7042_07820	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
G7042_07825	COG0291	Belongs to the bacterial ribosomal protein bL35 family
G7042_07830	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
G7042_07835	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
G7042_07860	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
G7042_07870	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
G7042_07875	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
G7042_07880	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
G7042_07885	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
G7042_07890	COG3313	Fe-S protein
G7042_07895	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
G7042_07895	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
G7042_07895	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
G7042_07900	COG1105	Belongs to the carbohydrate kinase PfkB family
G7042_07905	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
G7042_07905	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
G7042_07910	COG1609	Transcriptional regulator
G7042_07915	COG0814	amino acid
G7042_07925	COG5654	RES domain protein
G7042_07930	COG0513	Belongs to the DEAD box helicase family
G7042_07940	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
G7042_07945	COG2890	protein-(glutamine-N5) methyltransferase activity
G7042_07950	COG2840	Smr protein MutS2
G7042_07955	COG3706	GGDEF domain
G7042_08005	COG2824	Alkylphosphonate utilization operon protein PhnA
G7042_08010	COG1024	Enoyl-CoA hydratase
G7042_08010	COG1250	3-hydroxyacyl-CoA dehydrogenase
G7042_08015	COG0183	Belongs to the thiolase family
G7042_08020	COG0714	Associated with various cellular activities
G7042_08060	COG2067	long-chain fatty acid transport protein
G7042_08065	COG2067	long-chain fatty acid transport protein
G7042_08070	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
G7042_08090	COG3123	guanosine phosphorylase activity
G7042_08095	COG1760	l-serine dehydratase
G7042_08100	COG1760	l-serine dehydratase
G7042_08105	COG2951	lytic endotransglycosylase activity
G7042_08110	COG3100	YcgL domain-containing protein
G7042_08115	COG0850	regulation of cytokinetic process
G7042_08120	COG2894	cell division
G7042_08125	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
G7042_08130	COG3099	Belongs to the UPF0263 family
G7042_08135	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
G7042_08180	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
G7042_08185	COG0697	spore germination
G7042_08190	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
G7042_08195	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
G7042_08205	COG0307	riboflavin synthase, alpha
G7042_08215	COG0534	Mate efflux family protein
G7042_08250	COG0417	DNA replication proofreading
G7042_08280	COG1560	Kdo2-lipid A biosynthetic process
G7042_08290	COG0583	DNA-binding transcription factor activity
G7042_08295	COG0673	inositol 2-dehydrogenase activity
G7042_08300	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
G7042_08305	COG0583	DNA-binding transcription factor activity
G7042_08315	COG2723	6-phospho-beta-galactosidase activity
G7042_08320	COG0583	DNA-binding transcription factor activity
G7042_08350	COG3134	Outer membrane lipoprotein
G7042_08370	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
G7042_08390	COG4681	YaeQ
G7042_08425	COG0242	peptide deformylase activity
G7042_08450	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
G7042_08455	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
G7042_08460	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
G7042_08470	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
G7042_08480	COG1434	Gram-negative-bacterium-type cell wall biogenesis
G7042_08490	COG0205	6-phosphofructokinase activity
G7042_08530	COG1011	Hydrolase
G7042_08585	COG3593	DNA synthesis involved in DNA repair
G7042_08600	COG0583	DNA-binding transcription factor activity
G7042_08605	COG0730	response to heat
G7042_08610	COG3148	PFAM DTW domain containing protein
G7042_08620	COG1181	Belongs to the D-alanine--D-alanine ligase family
G7042_08630	COG0386	Belongs to the glutathione peroxidase family
G7042_08635	COG0513	Belongs to the DEAD box helicase family
G7042_08650	COG1742	UPF0060 membrane protein
G7042_08690	COG2329	Antibiotic biosynthesis monooxygenase
G7042_08695	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
G7042_08715	COG3243	poly(R)-hydroxyalkanoic acid synthase
G7042_08725	COG2501	S4 domain
G7042_08735	COG1132	(ABC) transporter
G7042_08750	COG3118	belongs to the thioredoxin family
G7042_08755	COG0471	metal ion transport
G7042_08760	COG0058	SHG alpha-glucan phosphorylase activity
G7042_08805	COG5433	transposase activity
G7042_08830	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
G7042_08840	COG0814	amino acid
G7042_08845	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
G7042_08850	COG0514	ATP-dependent DNA helicase (RecQ)
G7042_08855	COG2766	serine protein kinase
G7042_08865	COG2719	SpoVR family
G7042_08870	COG2186	Transcriptional regulator
G7042_08875	COG3067	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
G7042_08880	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
G7042_08885	COG0586	Pfam SNARE associated Golgi protein
G7042_08895	COG0556	nucleotide-excision repair
G7042_08905	COG0569	domain protein
G7042_08905	COG2985	domain, Protein
G7042_08910	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
G7042_08915	COG5433	transposase activity
G7042_08945	COG4565	transcriptional regulatory protein
G7042_08950	COG3290	protein histidine kinase activity
G7042_08955	COG1846	Transcriptional regulator
G7042_08955	COG1940	carbohydrate kinase activity
G7042_08960	COG0840	transmembrane signaling receptor activity
G7042_08965	COG3012	SEC-C Motif Domain Protein
G7042_08970	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
G7042_08975	COG3075	Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses fumarate or nitrate as electron acceptor
G7042_08980	COG0247	lactate metabolic process
G7042_08990	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
G7042_08995	COG0437	4 iron, 4 sulfur cluster binding
G7042_09000	COG3301	Polysulphide reductase, NrfD
G7042_09015	COG3088	subunit of a heme lyase
G7042_09015	COG4235	cytochrome complex assembly
G7042_09030	COG3033	Beta-eliminating lyase
G7042_09040	COG3046	protein related to deoxyribodipyrimidine photolyase
G7042_09070	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
G7042_09075	COG0583	DNA-binding transcription factor activity
G7042_09085	COG4774	siderophore transport
G7042_09090	COG3708	Transcriptional regulator
G7042_09090	COG2207	Transcriptional regulator
G7042_09100	COG0583	DNA-binding transcription factor activity
G7042_09105	COG2910	NAD(P)H-binding
G7042_09125	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
G7042_09130	COG1944	ATP diphosphatase activity
G7042_09135	COG2116	formate transmembrane transporter activity
G7042_09140	COG1882	Formate acetyltransferase
G7042_09145	COG2983	Belongs to the UPF0260 family
G7042_09150	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
G7042_09155	COG0045	succinate-CoA ligase (ADP-forming) activity
G7042_09160	COG0508	dehydrogenase complex catalyzes the overall conversion of
G7042_09165	COG0567	Dehydrogenase, E1 component
G7042_09175	COG1053	succinate dehydrogenase
G7042_09180	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
G7042_09205	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
G7042_09210	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
G7042_09210	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
G7042_09220	COG3069	C4-dicarboxylate transmembrane transporter activity
G7042_09235	COG1451	nucleotide metabolic process
G7042_09250	COG0254	rRNA binding
G7042_09255	COG0257	Belongs to the bacterial ribosomal protein bL36 family
G7042_09275	COG3867	Arabinogalactan endo-beta-1,4-galactanase
G7042_09280	COG3833	ABC-type maltose transport systems, permease component
G7042_09340	COG4580	involved in the transport of maltose and maltodextrins
G7042_09345	COG1609	Transcriptional regulator
G7042_09350	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
G7042_09370	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
G7042_09380	COG1172	Belongs to the binding-protein-dependent transport system permease family
G7042_09385	COG1129	ABC transporter
G7042_09390	COG1879	ABC-type sugar transport system periplasmic component
G7042_09395	COG1069	ribulokinase activity
G7042_09405	COG2160	L-arabinose isomerase activity
G7042_09410	COG0583	DNA-binding transcription factor activity
G7042_09415	COG0436	Aminotransferase
G7042_09420	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
G7042_09435	COG2925	Exonuclease
G7042_09445	COG3345	alpha-galactosidase
G7042_09455	COG1380	Effector of murein hydrolase LrgA
G7042_09460	COG1346	cytolysis
G7042_09465	COG0295	cytidine deaminase activity
G7042_09470	COG1022	Amp-dependent synthetase and ligase
G7042_09485	COG0861	Integral membrane protein TerC family
G7042_09495	COG2199	diguanylate cyclase activity
G7042_09510	COG2154	pterin-4-alpha-carbinolamine dehydratase
G7042_09520	COG3768	UPF0283 membrane protein
G7042_09525	COG3106	COG3106 Predicted ATPase
G7042_09540	COG1842	Phage shock protein A
G7042_09545	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
G7042_09555	COG4168	peptide transport system, permease
G7042_09560	COG4171	peptide transport system, permease
G7042_09565	COG4172	Belongs to the ABC transporter superfamily
G7042_09570	COG4172	Belongs to the ABC transporter superfamily
G7042_09580	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
G7042_09585	COG1286	toxin biosynthetic process
G7042_09590	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
G7042_09595	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
G7042_09600	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
G7042_09605	COG1674	ftsk spoiiie
G7042_09605	COG0531	amino acid
G7042_09625	COG0492	ferredoxin-NADP+ reductase activity
G7042_09635	COG3134	Outer membrane lipoprotein
G7042_09640	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
G7042_09645	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
G7042_09650	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
G7042_09655	COG0542	response to heat
G7042_09660	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
G7042_09665	COG1278	Cold shock
G7042_09670	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
G7042_09730	COG3829	transcription factor binding
G7042_09800	COG0659	secondary active sulfate transmembrane transporter activity
G7042_09850	COG0697	spore germination
G7042_09855	COG4657	Part of a membrane complex involved in electron transport
G7042_09860	COG2878	Part of a membrane complex involved in electron transport
G7042_09870	COG4658	electron transport chain
G7042_09875	COG4659	FMN binding
G7042_09880	COG4660	Part of a membrane complex involved in electron transport
G7042_09885	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
G7042_09890	COG0346	lactoylglutathione lyase activity
G7042_09905	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
G7042_09910	COG2056	Na+-H+ antiporter family
G7042_09915	COG5001	Diguanylate cyclase
G7042_09915	COG3300	MHYT domain
G7042_09925	COG0513	Belongs to the DEAD box helicase family
G7042_09930	COG2050	protein possibly involved in aromatic compounds catabolism
G7042_09940	COG0277	FAD linked oxidase domain protein
G7042_09940	COG0247	lactate metabolic process
G7042_09950	COG1253	flavin adenine dinucleotide binding
G7042_09955	COG1902	pentaerythritol trinitrate reductase activity
G7042_09965	COG0647	UMP catabolic process
G7042_09970	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
G7042_09970	COG4651	solute:proton antiporter activity
G7042_09980	COG0367	asparagine synthase
G7042_10005	COG0625	glutathione transferase activity
G7042_10010	COG0625	glutathione transferase activity
G7042_10035	COG0564	pseudouridine synthase activity
G7042_10055	COG0840	transmembrane signaling receptor activity
G7042_10065	COG0670	Belongs to the BI1 family
G7042_10070	COG1289	transmembrane transporter activity
G7042_10075	COG2920	part of a sulfur-relay system
G7042_10080	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
G7042_10085	COG0285	dihydrofolate synthase activity
G7042_10090	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
G7042_10095	COG0101	tRNA pseudouridine synthase activity
G7042_10105	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
G7042_10110	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
G7042_10115	COG0671	phosphoesterase, PA-phosphatase related
G7042_10135	COG5433	transposase activity
G7042_10170	COG0574	Belongs to the PEP-utilizing enzyme family
G7042_10170	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
G7042_10235	COG0672	)-iron permease
G7042_10260	COG2814	Major facilitator Superfamily
G7042_10275	COG1136	(ABC) transporter
G7042_10280	COG0577	efflux transmembrane transporter activity
G7042_10295	COG1285	pathogenesis
G7042_10350	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
G7042_10355	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
G7042_10355	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
G7042_10360	COG0527	aspartate kinase activity
G7042_10370	COG1368	sulfuric ester hydrolase activity
G7042_10375	COG1619	proteins homologs of microcin C7 resistance protein MccF
G7042_10385	COG0393	Putative heavy-metal-binding
G7042_10390	COG1252	NADH dehydrogenase
G7042_10425	COG0789	Transcriptional regulator
G7042_10440	COG0493	'glutamate synthase
G7042_10445	COG0069	glutamate synthase activity
G7042_10445	COG0067	glutamate synthase
G7042_10445	COG0070	glutamate synthase
G7042_10450	COG5433	transposase activity
G7042_10500	COG0513	Belongs to the DEAD box helicase family
G7042_10505	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
G7042_10535	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
G7042_10540	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
G7042_10545	COG0505	Belongs to the CarA family
G7042_10550	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
G7042_10565	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
G7042_10570	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
G7042_10575	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
G7042_10580	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
G7042_10585	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
G7042_10590	COG4138	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system
G7042_10600	COG2205	protein histidine kinase activity
G7042_10600	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
G7042_10645	COG2119	membrane
G7042_10675	COG2203	Gaf domain
G7042_10675	COG2199	diguanylate cyclase activity
G7042_10700	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
G7042_10710	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
G7042_10715	COG2261	transglycosylase associated protein
G7042_10755	COG0322	excinuclease ABC activity
G7042_10760	COG2197	response regulator
G7042_10765	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
G7042_10770	COG2835	tetraacyldisaccharide 4'-kinase activity
G7042_10775	COG1663	tetraacyldisaccharide 4'-kinase activity
G7042_10780	COG1132	(ABC) transporter
G7042_10785	COG0658	competence protein
G7042_10785	COG2333	competence protein COMEC
G7042_10800	COG0433	COG0433 Predicted ATPase
G7042_10805	COG1448	Aminotransferase
G7042_10820	COG1199	ATP-dependent helicase activity
G7042_10835	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
G7042_10840	COG1785	Belongs to the alkaline phosphatase family
G7042_10860	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
G7042_10875	COG2271	Major facilitator Superfamily
G7042_10880	COG3706	GGDEF domain
G7042_10885	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
G7042_10890	COG0765	amino acid transport
G7042_10895	COG1126	abc transporter atp-binding protein
G7042_10905	COG0531	amino acid
G7042_10920	COG1253	flavin adenine dinucleotide binding
G7042_10925	COG0704	Plays a role in the regulation of phosphate uptake
G7042_10930	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
G7042_10935	COG0581	inorganic phosphate transmembrane transporter activity
G7042_10940	COG0573	inorganic phosphate transmembrane transporter activity
G7042_10945	COG0590	tRNA wobble adenosine to inosine editing
G7042_10955	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
G7042_10975	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
G7042_10980	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
G7042_10985	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
G7042_10990	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
G7042_11020	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
G7042_11025	COG0248	Ppx GppA phosphatase
G7042_11030	COG2239	Acts as a magnesium transporter
G7042_11065	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
G7042_11075	COG4787	bacterial-type flagellum-dependent cell motility
G7042_11095	COG1815	bacterial-type flagellum-dependent cell motility
G7042_11100	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
G7042_11105	COG0835	chemotaxis
G7042_11105	COG0784	Response regulator, receiver
G7042_11125	COG0622	Phosphoesterase
G7042_11130	COG4166	transmembrane transport
G7042_11155	COG0697	spore germination
G7042_11195	COG1278	Cold shock
G7042_11250	COG3132	Protein of unknown function, DUF480
G7042_11265	COG5433	transposase activity
G7042_11290	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
G7042_11305	COG5433	transposase activity
G7042_11315	COG0471	metal ion transport
G7042_11315	COG3273	potassium ion transport
G7042_11320	COG5433	transposase activity
G7042_11340	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
G7042_11345	COG0438	transferase activity, transferring glycosyl groups
G7042_11365	COG1450	Type ii and iii secretion system protein
G7042_11410	COG1459	type II secretion system
G7042_11415	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
G7042_11435	COG1091	dTDP-4-dehydrorhamnose reductase activity
G7042_11460	COG1309	transcriptional regulator
G7042_11475	COG1946	Acyl-CoA thioesterase
G7042_11485	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
G7042_11495	COG0009	L-threonylcarbamoyladenylate synthase
G7042_11510	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
G7042_11515	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
G7042_11515	COG0512	Glutamine amidotransferase of anthranilate synthase
G7042_11520	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
G7042_11525	COG0135	phosphoribosylanthranilate isomerase activity
G7042_11525	COG0134	indole-3-glycerol-phosphate synthase activity
G7042_11530	COG0133	tryptophan synthase activity
G7042_11535	COG0159	tryptophan synthase activity
G7042_11585	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
G7042_11585	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
G7042_11585	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
G7042_11595	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
G7042_11615	COG0482	sulfurtransferase activity
G7042_11620	COG2915	High frequency lysogenization protein hflD homolog
G7042_11625	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
G7042_11630	COG2850	peptidyl-arginine hydroxylation
G7042_11665	COG0259	pyridoxamine-phosphate oxidase activity
G7042_11680	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
G7042_11680	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
G7042_11685	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
G7042_11705	COG4235	cytochrome complex assembly
G7042_11705	COG3088	subunit of a heme lyase
G7042_11710	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
G7042_11715	COG1138	Cytochrome C-type biogenesis protein
G7042_11720	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
G7042_11725	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
G7042_11730	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
G7042_11735	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
G7042_11755	COG0835	chemotaxis
G7042_11765	COG1192	Involved in chromosome partitioning
G7042_11770	COG1360	Flagellar Motor Protein
G7042_11775	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
G7042_11780	COG2201	protein-glutamate methylesterase activity
G7042_11785	COG2198	Histidine kinase
G7042_11785	COG0784	Response regulator, receiver
G7042_11785	COG0643	Histidine kinase
G7042_11795	COG0583	DNA-binding transcription factor activity
G7042_11805	COG0791	NLP P60 protein
G7042_11820	COG1309	transcriptional regulator
G7042_11860	COG0534	Mate efflux family protein
G7042_11870	COG2841	Protein conserved in bacteria
G7042_11875	COG1013	pyruvate-flavodoxin oxidoreductase activity
G7042_11875	COG0674	pyruvate-flavodoxin oxidoreductase activity
G7042_11875	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
G7042_11875	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
G7042_11890	COG3217	Mosc domain protein beta barrel domain protein
G7042_11890	COG0633	Ferredoxin
G7042_11890	COG0633	Ferredoxin
G7042_11890	COG3217	Mosc domain protein beta barrel domain protein
G7042_11900	COG0501	Belongs to the peptidase M48B family
G7042_11905	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
G7042_11910	COG2226	methyltransferase
G7042_11910	COG1073	alpha beta
G7042_11915	COG0156	8-amino-7-oxononanoate synthase activity
G7042_11920	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
G7042_11940	COG0017	Asparaginyl-tRNA synthetase
G7042_11960	COG0583	DNA-binding transcription factor activity
G7042_11965	COG1393	Belongs to the ArsC family
G7042_11970	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
G7042_11975	COG1876	peptidase activity
G7042_11985	COG3263	regulation of cellular component size
G7042_12005	COG5433	transposase activity
G7042_12015	COG1280	lysine exporter protein (LysE YggA)
G7042_12020	COG0840	transmembrane signaling receptor activity
G7042_12040	COG1957	nucleoside hydrolase
G7042_12055	COG1454	alcohol dehydrogenase
G7042_12095	COG2894	cell division
G7042_12105	COG4964	Belongs to the GSP D family
G7042_12135	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
G7042_12140	COG0702	epimerase
G7042_12145	COG2914	Belongs to the UPF0125 (RnfH) family
G7042_12150	COG2867	negative regulation of translational initiation
G7042_12160	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
G7042_12170	COG0582	viral genome integration into host DNA
G7042_12215	COG0538	isocitrate dehydrogenase activity
G7042_12220	COG2207	Transcriptional regulator
G7042_12235	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
G7042_12250	COG5433	transposase activity
G7042_12270	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
G7042_12270	COG1263	PTS System
G7042_12275	COG1609	Transcriptional regulator
G7042_12310	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
G7042_12315	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
G7042_12320	COG1845	cytochrome c oxidase, subunit III
G7042_12325	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
G7042_12330	COG0109	protoheme IX farnesyltransferase activity
G7042_12335	COG2814	Major facilitator Superfamily
G7042_12390	COG0708	Exodeoxyribonuclease III
G7042_12430	COG0095	Lipoate-protein ligase
G7042_12475	COG1285	pathogenesis
G7042_12505	COG0484	heat shock protein binding
G7042_12510	COG0443	Heat shock 70 kDa protein
G7042_12515	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
G7042_12520	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
G7042_12525	COG0497	DNA recombination
G7042_12535	COG1227	inorganic diphosphatase activity
G7042_12545	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
G7042_12550	COG0577	efflux transmembrane transporter activity
G7042_12550	COG1136	(ABC) transporter
G7042_12555	COG1538	Outer membrane efflux protein
G7042_12560	COG2375	cellular response to nickel ion
G7042_12565	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
G7042_12570	COG3328	transposase activity
G7042_12575	COG2916	Histone family protein nucleoid-structuring protein H-NS
G7042_12600	COG2201	protein-glutamate methylesterase activity
G7042_12605	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
G7042_12650	COG2203	Gaf domain
G7042_12650	COG2200	EAL domain
G7042_12650	COG2199	diguanylate cyclase activity
G7042_12655	COG0826	peptidase U32
G7042_12660	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
G7042_12665	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
G7042_12680	COG2200	EAL domain
G7042_12685	COG0737	Belongs to the 5'-nucleotidase family
G7042_12705	COG2204	response regulator
G7042_12710	COG0545	Peptidyl-prolyl cis-trans isomerase
G7042_12725	COG1047	Peptidyl-prolyl cis-trans
G7042_12730	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
G7042_12740	COG0835	chemotaxis
G7042_12740	COG0784	Response regulator, receiver
G7042_12745	COG0429	hydrolase of the alpha beta-hydrolase fold
G7042_12750	COG5001	Diguanylate cyclase
G7042_12750	COG4251	negative regulation of phosphorylation
G7042_12750	COG2203	Gaf domain
G7042_12750	COG3706	GGDEF domain
G7042_12755	COG3089	Belongs to the UPF0270 family
G7042_12780	COG0463	Glycosyl transferase, family 2
G7042_12790	COG0726	polysaccharide deacetylase
G7042_12795	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
G7042_12800	COG2076	Multidrug Resistance protein
G7042_12810	COG3954	Phosphoribulokinase
G7042_12825	COG1765	OsmC-like protein
G7042_12840	COG3397	chitin binding
G7042_12885	COG0748	coenzyme F420 binding
G7042_12890	COG3721	Heme iron utilization protein
G7042_12900	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
G7042_12925	COG0488	(ABC) transporter
G7042_12935	COG2252	PERMEase
G7042_12940	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
G7042_12945	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
G7042_12950	COG3178	'Phosphotransferase
G7042_12955	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
G7042_12965	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
G7042_12970	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
G7042_12975	COG2967	ApaG domain
G7042_12980	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
G7042_12995	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
G7042_13015	COG0318	PFAM AMP-dependent synthetase and ligase
G7042_13020	COG3314	Sporulation integral membrane protein YlbJ
G7042_13025	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
G7042_13030	COG0211	Belongs to the bacterial ribosomal protein bL27 family
G7042_13035	COG0261	This protein binds to 23S rRNA in the presence of protein L20
G7042_13040	COG0142	geranyltranstransferase activity
G7042_13045	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
G7042_13050	COG0330	HflC and HflK could
G7042_13055	COG0330	HflC and HflK could
G7042_13060	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
G7042_13065	COG1923	regulation of RNA biosynthetic process
G7042_13070	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
G7042_13075	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
G7042_13085	COG0802	atpase or kinase
G7042_13090	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
G7042_13090	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
G7042_13110	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
G7042_13115	COG2011	ABC-type metal ion transport system permease component
G7042_13120	COG1464	Belongs to the NlpA lipoprotein family
G7042_13130	COG0840	transmembrane signaling receptor activity
G7042_13155	COG2198	Histidine kinase
G7042_13155	COG5002	protein histidine kinase activity
G7042_13155	COG0784	Response regulator, receiver
G7042_13190	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
G7042_13195	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
G7042_13205	COG2716	regulation of RNA biosynthetic process
G7042_13210	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
G7042_13215	COG3013	Belongs to the UPF0304 family
G7042_13225	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
G7042_13230	COG0857	belongs to the CobB CobQ family
G7042_13230	COG0280	phosphate acetyltransferase
G7042_13235	COG0440	acetolactate synthase activity
G7042_13240	COG0028	Belongs to the TPP enzyme family
G7042_13255	COG0671	phosphoesterase, PA-phosphatase related
G7042_13265	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
G7042_13270	COG0473	3-isopropylmalate dehydrogenase activity
G7042_13275	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
G7042_13280	COG0066	3-isopropylmalate dehydratase activity
G7042_13295	COG4143	(ABC) transporter
G7042_13300	COG1178	ABC-type Fe3 transport system permease component
G7042_13305	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
G7042_13310	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
G7042_13320	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
G7042_13350	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
G7042_13355	COG0564	pseudouridine synthase activity
G7042_13365	COG3300	MHYT domain
G7042_13365	COG5001	Diguanylate cyclase
G7042_13375	COG0459	protein refolding
G7042_13380	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
G7042_13385	COG0534	Mate efflux family protein
G7042_13390	COG3030	protein affecting phage T7 exclusion by the F plasmid
G7042_13395	COG1027	Aspartate ammonia-lyase
G7042_13400	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
G7042_13410	COG0477	Major facilitator Superfamily
G7042_13420	COG3227	Zinc metalloprotease (Elastase)
G7042_13425	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
G7042_13430	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
G7042_13445	COG0673	inositol 2-dehydrogenase activity
G7042_13455	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
G7042_13460	COG0635	Involved in the biosynthesis of porphyrin-containing compound
G7042_13465	COG3036	rescue of stalled ribosome
G7042_13470	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
G7042_13480	COG0138	bifunctional purine biosynthesis protein purh
G7042_13485	COG0151	Belongs to the GarS family
G7042_13525	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
G7042_13530	COG0358	DNA primase activity
G7042_13535	COG1610	YqeY-like protein
G7042_13540	COG0828	Belongs to the bacterial ribosomal protein bS21 family
G7042_13545	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
G7042_13555	COG1388	LysM domain
G7042_13555	COG4942	peptidase
G7042_13560	COG1238	metal cluster binding
G7042_13565	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
G7042_13570	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
G7042_13575	COG0585	pseudouridine synthase activity
G7042_13585	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
G7042_13590	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
G7042_13595	COG0148	phosphopyruvate hydratase activity
G7042_13600	COG0504	CTP synthase activity
G7042_13605	COG3956	TIGRFAM MazG family protein
G7042_13610	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
G7042_13615	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
G7042_13625	COG4807	Protein conserved in bacteria
G7042_13630	COG3023	N-Acetylmuramoyl-L-alanine amidase
G7042_13635	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
G7042_13640	COG1381	Involved in DNA repair and RecF pathway recombination
G7042_13650	COG0571	ribonuclease III activity
G7042_13660	COG0481	GTPase activity
G7042_13675	COG3073	An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E
G7042_13680	COG1595	DNA-templated transcription, initiation
G7042_13685	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
G7042_13735	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
G7042_13740	COG0191	fructose-bisphosphate aldolase activity
G7042_13745	COG0126	phosphoglycerate kinase activity
G7042_13750	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
G7042_13755	COG1940	carbohydrate kinase activity
G7042_13780	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
G7042_13790	COG1136	(ABC) transporter
G7042_13840	COG5433	transposase activity
G7042_13845	COG0529	Catalyzes the synthesis of activated sulfate
G7042_13850	COG0471	metal ion transport
G7042_13850	COG3273	potassium ion transport
G7042_13855	COG2895	sulfate adenylyltransferase (ATP) activity
G7042_13860	COG0175	sulfate reduction
G7042_13865	COG1648	precorrin-2 dehydrogenase activity
G7042_13865	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
G7042_13870	COG0330	HflC and HflK could
G7042_13875	COG1585	Membrane protein implicated in regulation of membrane protease activity
G7042_13880	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
G7042_13880	COG0517	IMP dehydrogenase activity
G7042_13885	COG0488	(ABC) transporter
G7042_13895	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
G7042_13925	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
G7042_13940	COG0668	transmembrane transport
G7042_13950	COG2731	YhcH YjgK YiaL family protein
G7042_13960	COG1794	racemase activity, acting on amino acids and derivatives
G7042_13975	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
G7042_14000	COG0733	neurotransmitter:sodium symporter activity
G7042_14010	COG0733	neurotransmitter:sodium symporter activity
G7042_14025	COG0561	phosphatase activity
G7042_14060	COG1846	Transcriptional regulator
G7042_14065	COG1764	response to oxidative stress
G7042_14070	COG2130	NADP-dependent
G7042_14090	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
G7042_14095	COG1349	DNA-binding transcription factor activity
G7042_14135	COG1028	Short-chain dehydrogenase reductase Sdr
G7042_14145	COG2982	Protein involved in outer membrane biogenesis
G7042_14150	COG1505	serine-type exopeptidase activity
G7042_14165	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
G7042_14170	COG0745	RESPONSE REGULATOR receiver
G7042_14175	COG2205	protein histidine kinase activity
G7042_14180	COG2816	NAD+ diphosphatase activity
G7042_14210	COG0316	Belongs to the HesB IscA family
G7042_14220	COG0038	chloride channel
G7042_14225	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
G7042_14240	COG0671	phosphoesterase, PA-phosphatase related
G7042_14250	COG3437	response regulator, receiver
G7042_14250	COG0784	Response regulator, receiver
G7042_14255	COG0583	DNA-binding transcription factor activity
G7042_14260	COG2076	Multidrug Resistance protein
G7042_14270	COG0346	lactoylglutathione lyase activity
G7042_14275	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
G7042_14280	COG1643	Atp-dependent helicase
G7042_14290	COG1489	DNA binding
G7042_14295	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
G7042_14300	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
G7042_14305	COG0617	tRNA 3'-terminal CCA addition
G7042_14310	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
G7042_14315	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
G7042_14320	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
G7042_14330	COG0842	Transport permease protein
G7042_14335	COG1131	(ABC) transporter
G7042_14350	COG0163	prenyltransferase activity
G7042_14355	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
G7042_14360	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
G7042_14365	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
G7042_14375	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
G7042_14375	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
G7042_14375	COG0506	proline dehydrogenase activity
G7042_14380	COG4991	sh3 domain protein
G7042_14385	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
G7042_14405	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
G7042_14410	COG1640	4-alpha-glucanotransferase
G7042_14415	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
G7042_14420	COG0676	glucose-6-phosphate 1-epimerase activity
G7042_14425	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
G7042_14430	COG0840	transmembrane signaling receptor activity
G7042_14495	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
G7042_14500	COG2885	chlorophyll binding
G7042_14505	COG0823	Involved in the tonB-independent uptake of proteins
G7042_14520	COG0811	peptide transport
G7042_14525	COG0824	Thioesterase
G7042_14530	COG3790	cyd operon protein YbgE
G7042_14535	COG4890	Cyd operon protein YbgT
G7042_14540	COG1294	oxidase, subunit
G7042_14545	COG1271	oxidase subunit
G7042_14550	COG2255	four-way junction helicase activity
G7042_14555	COG0632	four-way junction helicase activity
G7042_14565	COG0442	prolyl-tRNA aminoacylation
G7042_14575	COG1902	pentaerythritol trinitrate reductase activity
G7042_14585	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
G7042_14615	COG0714	Associated with various cellular activities
G7042_14625	COG0456	acetyltransferase
G7042_14635	COG1022	Amp-dependent synthetase and ligase
G7042_14645	COG2918	glutathione biosynthetic process
G7042_14650	COG0612	Peptidase, M16
G7042_14655	COG1238	metal cluster binding
G7042_14660	COG1064	alcohol dehydrogenase
G7042_14690	COG0359	binds to the 23S rRNA
G7042_14695	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
G7042_14700	COG0360	Binds together with S18 to 16S ribosomal RNA
G7042_14705	COG1914	H( )-stimulated, divalent metal cation uptake system
G7042_14710	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
G7042_14735	COG2153	protein acetylation
G7042_14745	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
G7042_14750	COG0557	exoribonuclease II activity
G7042_14755	COG3706	GGDEF domain
G7042_14760	COG1854	S-ribosylhomocysteine lyase activity
G7042_14775	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
G7042_14775	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
G7042_14815	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
G7042_14820	COG1047	Peptidyl-prolyl cis-trans
G7042_14825	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
G7042_14830	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
G7042_14835	COG0196	riboflavin kinase activity
G7042_14840	COG0728	peptidoglycan biosynthetic process
G7042_14845	COG0268	Binds directly to 16S ribosomal RNA
G7042_14850	COG0640	Transcriptional regulator
G7042_14855	COG0583	DNA-binding transcription factor activity
G7042_14865	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
G7042_14870	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
G7042_14875	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
G7042_14885	COG1051	belongs to the nudix hydrolase family
G7042_14890	COG3066	DNA modification
G7042_14900	COG0335	large ribosomal subunit rRNA binding
G7042_14905	COG0336	Belongs to the RNA methyltransferase TrmD family
G7042_14910	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
G7042_14915	COG0228	four-way junction DNA binding
G7042_14920	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
G7042_14925	COG4137	Cytochrome C assembly protein
G7042_14930	COG4536	flavin adenine dinucleotide binding
G7042_14935	COG1959	2 iron, 2 sulfur cluster binding
G7042_14940	COG1017	nitric oxide dioxygenase activity
G7042_14940	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
G7042_14945	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
G7042_14950	COG0039	L-malate dehydrogenase activity
G7042_14955	COG4160	amino acid transport
G7042_14960	COG4215	(ABC) transporter
G7042_14965	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
G7042_14970	COG1126	abc transporter atp-binding protein
G7042_14975	COG1438	arginine binding
G7042_14980	COG2837	iron assimilation
G7042_14985	COG3842	ATPase activity
G7042_14995	COG1840	ABC-type Fe3 transport system, periplasmic component
G7042_15000	COG0347	Belongs to the P(II) protein family
G7042_15015	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
G7042_15035	COG1929	Belongs to the glycerate kinase type-1 family
G7042_15040	COG2610	gluconate transmembrane transporter activity
G7042_15045	COG3835	regulator
G7042_15050	COG3112	Uncharacterised protein family (UPF0231)
G7042_15065	COG0840	transmembrane signaling receptor activity
G7042_15070	COG3568	Endonuclease Exonuclease Phosphatase
G7042_15085	COG0513	Belongs to the DEAD box helicase family
G7042_15125	COG1448	Aminotransferase
G7042_15145	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
G7042_15150	COG1328	CTP reductase activity
G7042_15185	COG1215	transferase activity, transferring glycosyl groups
G7042_15190	COG1649	PFAM Uncharacterised BCR, COG1649
G7042_15190	COG0726	polysaccharide deacetylase
G7042_15225	COG0840	transmembrane signaling receptor activity
G7042_15230	COG3397	chitin binding
G7042_15235	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
G7042_15240	COG1126	abc transporter atp-binding protein
G7042_15250	COG0765	amino acid transport
G7042_15255	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
G7042_15260	COG0583	DNA-binding transcription factor activity
G7042_15265	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
G7042_15270	COG4208	sulfate ABC transporter
G7042_15280	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
G7042_15290	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
G7042_15295	COG3174	membrane
G7042_15300	COG0110	maltose O-acetyltransferase activity
G7042_15330	COG1942	4-Oxalocrotonate Tautomerase
G7042_15340	COG0583	DNA-binding transcription factor activity
G7042_15345	COG0165	Argininosuccinate lyase
G7042_15350	COG0137	argininosuccinate synthase activity
G7042_15360	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
G7042_15365	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
G7042_15375	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
G7042_15385	COG2072	flavoprotein involved in K transport
G7042_15390	COG1393	Belongs to the ArsC family
G7042_15395	COG0798	PFAM Bile acid sodium symporter
G7042_15415	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
G7042_15435	COG3068	Protein conserved in bacteria
G7042_15445	COG0739	heme binding
G7042_15465	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
G7042_15470	COG1121	(ABC) transporter
G7042_15475	COG1108	ABC-type Mn2 Zn2 transport systems permease components
G7042_15480	COG0583	DNA-binding transcription factor activity
G7042_15490	COG1573	uracil-dna glycosylase
G7042_15505	COG2827	Endonuclease containing a URI domain
G7042_15525	COG0204	Acyl-transferase
G7042_15545	COG3118	belongs to the thioredoxin family
G7042_15550	COG2259	Doxx family
G7042_15625	COG1051	belongs to the nudix hydrolase family
G7042_15630	COG3150	esterase
G7042_15640	COG3151	Protein conserved in bacteria
G7042_15645	COG0494	nUDIX hydrolase
G7042_15650	COG1538	Outer membrane efflux protein
G7042_15655	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
G7042_15655	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
G7042_15660	COG1560	Kdo2-lipid A biosynthetic process
G7042_15675	COG1392	Phosphate transport regulator
G7042_15680	COG0306	phosphate transporter
G7042_15685	COG0617	tRNA 3'-terminal CCA addition
G7042_15690	COG3409	Peptidoglycan-binding domain 1 protein
G7042_15690	COG3267	Type II secretory pathway component ExeA
G7042_15700	COG1194	a g-specific adenine glycosylase
G7042_15705	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
G7042_15715	COG3111	PFAM Bacterial OB fold (BOF) protein
G7042_15720	COG3240	lipase activity
G7042_15735	COG3009	Protein conserved in bacteria
G7042_15740	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
G7042_15740	COG3008	intermembrane lipid transfer
G7042_15745	COG2995	paraquat-inducible protein a
G7042_15755	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
G7042_15770	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
G7042_15775	COG2813	Specifically methylates the guanine in position
G7042_15780	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
G7042_15785	COG0297	glycogen (starch) synthase activity
G7042_15820	COG1757	Na H antiporter
G7042_15830	COG0110	maltose O-acetyltransferase activity
G7042_15835	COG0366	Alpha amylase catalytic
G7042_15840	COG1263	PTS System
G7042_15840	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
G7042_15855	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
G7042_15860	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
G7042_15865	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
G7042_15865	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
G7042_15870	COG2723	6-phospho-beta-galactosidase activity
G7042_15875	COG1447	Phosphotransferase system cellobiose-specific component IIA
G7042_15880	COG1940	carbohydrate kinase activity
G7042_15890	COG1609	Transcriptional regulator
G7042_15900	COG0252	asparaginase activity
G7042_15915	COG1803	Methylglyoxal synthase
G7042_15940	COG1444	tRNA N-acetyltransferase activity
G7042_15945	COG1028	Short-chain dehydrogenase reductase Sdr
G7042_15950	COG0784	Response regulator, receiver
G7042_15950	COG0835	chemotaxis
G7042_15960	COG3314	Sporulation integral membrane protein YlbJ
G7042_16085	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
G7042_16090	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
G7042_16110	COG0523	cobalamin synthesis protein
G7042_16120	COG1280	lysine exporter protein (LysE YggA)
G7042_16130	COG0583	DNA-binding transcription factor activity
G7042_16135	COG1028	Short-chain dehydrogenase reductase Sdr
G7042_16140	COG2200	EAL domain
G7042_16145	COG1049	propionate catabolic process, 2-methylcitrate cycle
G7042_16155	COG0840	transmembrane signaling receptor activity
G7042_16160	COG0840	transmembrane signaling receptor activity
G7042_16170	COG5001	Diguanylate cyclase
G7042_16170	COG3447	MASE1 domain protein
G7042_16170	COG5002	protein histidine kinase activity
G7042_16175	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
G7042_16180	COG0508	dehydrogenase complex catalyzes the overall conversion of
G7042_16185	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
G7042_16190	COG2186	Transcriptional regulator
G7042_16230	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
G7042_16240	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
G7042_16250	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
G7042_16255	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
G7042_16260	COG0494	nUDIX hydrolase
G7042_16270	COG0653	protein targeting
G7042_16280	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
G7042_16285	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
G7042_16290	COG0849	cell division
G7042_16295	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
G7042_16300	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
G7042_16305	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
G7042_16310	COG0772	Belongs to the SEDS family
G7042_16315	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
G7042_16320	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
G7042_16325	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
G7042_16335	COG0768	penicillin binding
G7042_16340	COG3116	cell division
G7042_16345	COG0275	rRNA processing
G7042_16350	COG2001	Belongs to the MraZ family
G7042_16360	COG0741	lytic transglycosylase activity
G7042_16360	COG1388	LysM domain
G7042_16365	COG1360	Flagellar Motor Protein
G7042_16370	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
G7042_16375	COG1191	sigma factor activity
G7042_16400	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
G7042_16405	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
G7042_16435	COG4786	Flagellar basal body rod
G7042_16435	COG1256	bacterial-type flagellum assembly
G7042_16445	COG1706	bacterial-type flagellum-dependent cell motility
G7042_16450	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
G7042_16455	COG4786	Flagellar basal body rod
G7042_16460	COG4786	Flagellar basal body rod
G7042_16465	COG1749	Flagellar hook protein flgE
G7042_16480	COG1815	bacterial-type flagellum-dependent cell motility
G7042_16490	COG2747	anti-sigma28 factor FlgM
G7042_16515	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
G7042_16525	COG1677	Flagellar hook-basal body complex protein FliE
G7042_16555	COG2197	response regulator
G7042_16560	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
G7042_16565	COG2199	diguanylate cyclase activity
G7042_16570	COG1278	Cold shock
G7042_16580	COG3706	GGDEF domain
G7042_16605	COG0347	Belongs to the P(II) protein family
G7042_16625	COG5433	transposase activity
G7042_16635	COG0346	lactoylglutathione lyase activity
G7042_16655	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
G7042_16660	COG1074	ATP-dependent DNA helicase activity
G7042_16665	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
G7042_16670	COG2259	Doxx family
G7042_16675	COG1741	Belongs to the pirin family
G7042_16685	COG0583	DNA-binding transcription factor activity
G7042_16710	COG1176	ABC-type spermidine putrescine transport system, permease component I
G7042_16720	COG3842	ATPase activity
G7042_16730	COG2203	Gaf domain
G7042_16730	COG2199	diguanylate cyclase activity
G7042_16750	COG1247	-acetyltransferase
G7042_16755	COG0753	catalase activity
G7042_16780	COG0494	nUDIX hydrolase
G7042_16785	COG0628	permease
G7042_16790	COG3284	Transcriptional regulator
G7042_16800	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
G7042_16800	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
G7042_16800	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
G7042_16805	COG1461	Dihydroxyacetone kinase
G7042_16810	COG2376	Dihydroxyacetone kinase
G7042_16815	COG2252	PERMEase
G7042_16865	COG0203	ribosomal protein L17
G7042_16870	COG0202	RNA polymerase activity
G7042_16875	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
G7042_16880	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
G7042_16885	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
G7042_16890	COG0257	Belongs to the bacterial ribosomal protein bL36 family
G7042_16895	COG0201	protein transport
G7042_16900	COG0200	Binds to the 23S rRNA
G7042_16905	COG1841	ribosomal large subunit assembly
G7042_16910	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
G7042_16915	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
G7042_16920	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
G7042_16925	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
G7042_16930	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
G7042_16935	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
G7042_16940	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
G7042_16945	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
G7042_16950	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
G7042_16955	COG0255	Belongs to the universal ribosomal protein uL29 family
G7042_16960	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
G7042_16965	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
G7042_16970	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
G7042_16975	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
G7042_16980	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
G7042_16985	COG0089	rRNA binding
G7042_16990	COG0088	Forms part of the polypeptide exit tunnel
G7042_16995	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
G7042_17000	COG0051	transcription antitermination factor activity, RNA binding
G7042_17020	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
G7042_17025	COG2183	response to ionizing radiation
G7042_17045	COG0596	Alpha beta hydrolase
G7042_17050	COG1040	competence protein
G7042_17055	COG0316	Belongs to the HesB IscA family
G7042_17055	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
G7042_17060	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
G7042_17065	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
G7042_17070	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
G7042_17075	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
G7042_17080	COG4942	peptidase
G7042_17090	COG1609	Transcriptional regulator
G7042_17095	COG0800	Aldolase
G7042_17100	COG0129	dihydroxy-acid dehydratase activity
G7042_17105	COG3265	gluconokinase activity
G7042_17110	COG2610	gluconate transmembrane transporter activity
G7042_17115	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
G7042_17120	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
G7042_17130	COG0456	acetyltransferase
G7042_17140	COG1490	D-aminoacyl-tRNA deacylase activity
G7042_17145	COG1295	ribonuclease BN
G7042_17150	COG1217	gtp-binding protein TYPA
G7042_17155	COG0174	glutamine synthetase
G7042_17165	COG3852	Histidine kinase
G7042_17170	COG2204	response regulator
G7042_17175	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
G7042_17180	COG0635	Involved in the biosynthesis of porphyrin-containing compound
G7042_17190	COG3078	GTPase activator activity
G7042_17200	COG0218	Necessary for normal cell division and for the maintenance of normal septation
G7042_17210	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
G7042_17215	COG0408	coproporphyrinogen oxidase activity
G7042_17220	COG0009	L-threonylcarbamoyladenylate synthase
G7042_17230	COG0551	DNA topoisomerase type I activity
G7042_17235	COG2922	Belongs to the Smg family
G7042_17240	COG0758	DNA mediated transformation
G7042_17245	COG1652	LysM domain
G7042_17250	COG0242	peptide deformylase activity
G7042_17255	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
G7042_17260	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
G7042_17260	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
G7042_17265	COG0569	domain protein
G7042_17270	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
G7042_17295	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
G7042_17300	COG0686	Belongs to the AlaDH PNT family
G7042_17305	COG0519	Catalyzes the synthesis of GMP from XMP
G7042_17305	COG0518	GMP synthase (glutamine-hydrolyzing) activity
G7042_17315	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
G7042_17325	COG1012	belongs to the aldehyde dehydrogenase family
G7042_17335	COG2962	Rard protein
G7042_17345	COG1280	lysine exporter protein (LysE YggA)
G7042_17365	COG2116	formate transmembrane transporter activity
G7042_17370	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
G7042_17370	COG1648	precorrin-2 dehydrogenase activity
G7042_17375	COG2239	Acts as a magnesium transporter
G7042_17385	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
G7042_17390	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
G7042_17400	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
G7042_17410	COG0514	ATP-dependent DNA helicase (RecQ)
G7042_17415	COG2050	protein possibly involved in aromatic compounds catabolism
G7042_17430	COG2258	MOSC domain
G7042_17435	COG1177	transmembrane transport
G7042_17440	COG1176	ABC-type spermidine putrescine transport system, permease component I
G7042_17445	COG3842	ATPase activity
G7042_17465	COG0174	glutamine synthetase
G7042_17485	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
G7042_17490	COG0443	Heat shock 70 kDa protein
G7042_17505	COG0366	Alpha amylase catalytic
G7042_17510	COG1086	Polysaccharide biosynthesis protein
G7042_17515	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
G7042_17540	COG0318	PFAM AMP-dependent synthetase and ligase
G7042_17560	COG1083	cytidylyl-transferase
G7042_17570	COG2089	acid synthase
G7042_17605	COG5433	transposase activity
G7042_17615	COG4310	Domain of unknown function (DUF2172)
G7042_17650	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
G7042_17655	COG0745	RESPONSE REGULATOR receiver
G7042_17660	COG2205	protein histidine kinase activity
G7042_17670	COG0281	malic enzyme
G7042_17675	COG0702	epimerase
G7042_17680	COG0254	rRNA binding
G7042_17685	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
G7042_17695	COG1309	transcriptional regulator
G7042_17715	COG0129	dihydroxy-acid dehydratase activity
G7042_17725	COG3978	acetolactate synthase activity
G7042_17735	COG0606	chelatase, subunit chli
G7042_17745	COG1683	Conserved Protein
G7042_17755	COG1335	isochorismatase
G7042_17765	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
G7042_17770	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
G7042_17775	COG3639	organic phosphonate transmembrane transporter activity
G7042_17780	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
G7042_17785	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
G7042_17795	COG3084	Protein conserved in bacteria
G7042_17800	COG5001	Diguanylate cyclase
G7042_17800	COG3706	GGDEF domain
G7042_17800	COG2203	Gaf domain
G7042_17800	COG4251	negative regulation of phosphorylation
G7042_17815	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
G7042_17825	COG1561	YicC-like family, N-terminal region
G7042_17860	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
G7042_17875	COG1063	alcohol dehydrogenase
G7042_17890	COG0210	DNA helicase
G7042_17895	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
G7042_17900	COG2166	iron-sulfur cluster assembly
G7042_17905	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
G7042_17935	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
G7042_17940	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
G7042_17945	COG1739	Uncharacterized protein family UPF0029
G7042_17950	COG0006	proline dipeptidase activity
G7042_17955	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
G7042_17960	COG1250	3-hydroxyacyl-CoA dehydrogenase
G7042_17960	COG1024	Enoyl-CoA hydratase
G7042_17965	COG0183	Belongs to the thiolase family
G7042_17990	COG0425	Belongs to the sulfur carrier protein TusA family
G7042_17995	COG0251	oxidation-reduction process
G7042_18000	COG2885	chlorophyll binding
G7042_18010	COG0752	glycyl-tRNA synthetase alpha subunit
G7042_18015	COG0751	glycine-tRNA ligase activity
G7042_18035	COG2188	Transcriptional regulator
G7042_18040	COG3604	Transcriptional regulator
G7042_18050	COG0446	pyridine nucleotide-disulphide oxidoreductase
G7042_18060	COG0348	domain, Protein
G7042_18065	COG0814	amino acid
G7042_18080	COG2200	EAL domain
G7042_18080	COG2199	diguanylate cyclase activity
G7042_18080	COG2202	Pas domain
G7042_18115	COG3328	transposase activity
G7042_18155	COG1609	Transcriptional regulator
G7042_18195	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
G7042_18220	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
G7042_18235	COG3118	belongs to the thioredoxin family
G7042_18240	COG0513	Belongs to the DEAD box helicase family
G7042_18245	COG0248	Ppx GppA phosphatase
G7042_18255	COG0742	ribosomal rna small subunit methyltransferase
G7042_18260	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
G7042_18280	COG0084	hydrolase, TatD family'
G7042_18285	COG0805	protein transport
G7042_18290	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
G7042_18300	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
G7042_18305	COG3165	ubiquinone biosynthetic process from chorismate
G7042_18315	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
G7042_18320	COG0402	S-adenosylhomocysteine deaminase activity
G7042_18360	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
G7042_18365	COG0848	biopolymer transport protein
G7042_18370	COG0811	peptide transport
G7042_18375	COG0811	peptide transport
G7042_18385	COG2771	luxR family
G7042_18390	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
G7042_18395	COG1349	DNA-binding transcription factor activity
G7042_18400	COG0745	RESPONSE REGULATOR receiver
G7042_18405	COG2205	protein histidine kinase activity
G7042_18415	COG4452	Inner membrane protein CreD
G7042_18420	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
G7042_18425	COG0355	proton-transporting ATP synthase activity, rotational mechanism
G7042_18430	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
G7042_18435	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
G7042_18440	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
G7042_18445	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
G7042_18450	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
G7042_18460	COG0356	it plays a direct role in the translocation of protons across the membrane
G7042_18465	COG3312	ion transport
G7042_18470	COG1475	DNA binding
G7042_18475	COG1192	Involved in chromosome partitioning
G7042_18480	COG0357	Ribosomal RNA small subunit methyltransferase G
G7042_18485	COG0445	tRNA wobble uridine modification
G7042_18490	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
G7042_18495	COG4774	siderophore transport
G7042_18500	COG4615	Cyclic peptide transporter
G7042_18505	COG1120	ATPase activity
G7042_18510	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
G7042_18520	COG4774	siderophore transport
G7042_18525	COG4607	ABC-type enterochelin transport system periplasmic component
G7042_18530	COG4604	ABC transporter, ATP-binding protein
G7042_18535	COG4605	iron ion homeostasis
G7042_18540	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
G7042_18545	COG1132	(ABC) transporter
G7042_18550	COG2375	cellular response to nickel ion
G7042_18550	COG1132	(ABC) transporter
G7042_18560	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
G7042_18570	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
G7042_18585	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
G7042_18590	COG0706	membrane insertase activity
G7042_18595	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
G7042_18600	COG0594	ribonuclease P activity
G7042_18605	COG0230	Belongs to the bacterial ribosomal protein bL34 family
G7042_18610	COG1126	abc transporter atp-binding protein
G7042_18625	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
G7042_18630	COG0592	DNA-directed DNA polymerase activity
G7042_18655	COG2378	regulation of single-species biofilm formation
G7042_18660	COG0071	Belongs to the small heat shock protein (HSP20) family
G7042_18665	COG0071	Belongs to the small heat shock protein (HSP20) family
G7042_18680	COG3977	Valine--pyruvate aminotransferase
G7042_18695	COG2814	Major facilitator Superfamily
G7042_18705	COG0745	RESPONSE REGULATOR receiver
G7042_18710	COG2205	protein histidine kinase activity
G7042_18730	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
G7042_18735	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
G7042_18735	COG4191	Histidine kinase
G7042_18740	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
G7042_18745	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
G7042_18750	COG1309	transcriptional regulator
G7042_18780	COG0561	phosphatase activity
G7042_18785	COG2267	carboxylic ester hydrolase activity
G7042_18790	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
G7042_18795	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
G7042_18800	COG1758	RNA polymerase activity
G7042_18805	COG0194	GDP metabolic process
G7042_18810	COG0859	PFAM glycosyl transferase family 9
G7042_18815	COG3642	lipopolysaccharide core region biosynthetic process
G7042_18855	COG0589	response to stress
G7042_18860	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
G7042_18870	COG1528	Iron-storage protein
G7042_18875	COG2081	HI0933 family
G7042_18925	COG5433	transposase activity
G7042_18930	COG2205	protein histidine kinase activity
G7042_18930	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
G7042_18940	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
G7042_18940	COG2205	protein histidine kinase activity
G7042_18950	COG3275	phosphorelay sensor kinase activity
G7042_18955	COG3279	Response regulator of the LytR AlgR family
G7042_18960	COG2223	nitrite transmembrane transporter activity
G7042_18965	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
G7042_18970	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
G7042_18985	COG0583	DNA-binding transcription factor activity
G7042_18990	COG4206	TonB-dependent receptor
G7042_18995	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
G7042_19040	COG0583	DNA-binding transcription factor activity
G7042_19045	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
G7042_19050	COG0166	Belongs to the GPI family
G7042_19060	COG0668	transmembrane transport
G7042_19065	COG1309	transcriptional regulator
G7042_19070	COG0756	dUTP diphosphatase activity
G7042_19075	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
G7042_19080	COG2003	Belongs to the UPF0758 family
G7042_19085	COG0227	Belongs to the bacterial ribosomal protein bL28 family
G7042_19090	COG0267	Belongs to the bacterial ribosomal protein bL33 family
G7042_19100	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
G7042_19105	COG2990	Protein conserved in bacteria
G7042_19110	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
G7042_19115	COG0859	PFAM glycosyl transferase family 9
G7042_19120	COG0463	Glycosyl transferase, family 2
G7042_19125	COG0859	PFAM glycosyl transferase family 9
G7042_19130	COG1519	Transferase
G7042_19145	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
G7042_19150	COG1609	Transcriptional regulator
G7042_19180	COG1580	Controls the rotational direction of flagella during chemotaxis
G7042_19185	COG3161	chorismate lyase activity
G7042_19190	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
G7042_19195	COG2937	Belongs to the GPAT DAPAT family
G7042_19200	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
G7042_19215	COG0534	Mate efflux family protein
G7042_19220	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
G7042_19225	COG2205	protein histidine kinase activity
G7042_19230	COG0745	RESPONSE REGULATOR receiver
G7042_19240	COG1045	serine acetyltransferase
G7042_19250	COG3074	FtsZ-dependent cytokinesis
G7042_19255	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
G7042_19265	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
G7042_19315	COG1609	Transcriptional regulator
G7042_19320	COG0385	Bile acid
G7042_19325	COG1262	PFAM Formylglycine-generating sulfatase enzyme
G7042_19345	COG0583	DNA-binding transcription factor activity
G7042_19350	COG1079	Belongs to the binding-protein-dependent transport system permease family
G7042_19355	COG4603	Belongs to the binding-protein-dependent transport system permease family
G7042_19360	COG3845	ABC transporter
G7042_19365	COG1744	ABC transporter substrate-binding protein PnrA-like
G7042_19370	COG0210	DNA helicase
G7042_19410	COG2391	methyltransferase activity
G7042_19415	COG5433	transposase activity
G7042_19425	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
G7042_19440	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
G7042_19445	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
G7042_19455	COG0018	arginyl-trna synthetase
G7042_19465	COG1595	DNA-templated transcription, initiation
G7042_19475	COG1968	undecaprenyl-diphosphatase activity
G7042_19480	COG0667	Aldo Keto reductase
G7042_19485	COG2017	converts alpha-aldose to the beta-anomer
G7042_19490	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
G7042_19500	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
G7042_19505	COG1609	Transcriptional regulator
G7042_19510	COG3250	beta-galactosidase activity
G7042_19525	COG4211	Belongs to the binding-protein-dependent transport system permease family
G7042_19535	COG3328	transposase activity
G7042_19570	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
G7042_19575	COG1288	antiporter activity
G7042_19580	COG1438	arginine binding
G7042_19585	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
G7042_19590	COG0540	Belongs to the ATCase OTCase family
G7042_19610	COG0688	phosphatidylethanolamine metabolic process
G7042_19620	COG3040	lipid binding
G7042_19630	COG1979	alcohol dehydrogenase
G7042_19635	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
G7042_19640	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
G7042_19650	COG2964	Protein conserved in bacteria
G7042_19655	COG3681	Belongs to the UPF0597 family
G7042_19665	COG0446	pyridine nucleotide-disulphide oxidoreductase
G7042_19670	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
G7042_19675	COG0564	pseudouridine synthase activity
G7042_19685	COG0542	response to heat
G7042_19690	COG2502	aspartate--ammonia ligase
G7042_19695	COG1522	sequence-specific DNA binding
G7042_19705	COG5413	integral membrane protein
G7042_19710	COG0617	tRNA 3'-terminal CCA addition
G7042_19710	COG0517	IMP dehydrogenase activity
G7042_19710	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
G7042_19715	COG1028	Short-chain dehydrogenase reductase Sdr
G7042_19730	COG2205	protein histidine kinase activity
G7042_19740	COG2204	response regulator
G7042_19750	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
G7042_19755	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
G7042_19785	COG0243	molybdopterin cofactor binding
G7042_19790	COG3005	denitrification pathway
G7042_19795	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
G7042_19800	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
G7042_19805	COG0569	domain protein
G7042_19810	COG0812	UDP-N-acetylmuramate dehydrogenase activity
G7042_19835	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
G7042_19850	COG0250	Participates in transcription elongation, termination and antitermination
G7042_19855	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
G7042_19860	COG0081	regulation of translation
G7042_19865	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
G7042_19870	COG0222	ribosome binding
G7042_19875	COG0085	RNA polymerase activity
G7042_19880	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
G7042_19885	COG2964	Protein conserved in bacteria
G7042_19900	COG2923	Belongs to the DsrF TusC family
G7042_19905	COG2168	tRNA wobble position uridine thiolation
G7042_19910	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
G7042_19915	COG0049	tRNA binding
G7042_19920	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
G7042_19925	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
G7042_19930	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
G7042_19990	COG3047	cAMP biosynthetic process
G7042_20020	COG3135	benzoate transporter
G7042_20025	COG1396	sequence-specific DNA binding
G7042_20055	COG2926	Belongs to the UPF0265 family
G7042_20065	COG3028	Belongs to the UPF0307 family
G7042_20070	COG0312	modulator of DNA gyrase
G7042_20075	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
G7042_20080	COG5007	Belongs to the BolA IbaG family
G7042_20090	COG2854	intermembrane phospholipid transfer
G7042_20095	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
G7042_20100	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
G7042_20105	COG1127	ABC transporter
G7042_20110	COG0517	IMP dehydrogenase activity
G7042_20110	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
G7042_20115	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
G7042_20120	COG3117	lipopolysaccharide transmembrane transporter activity
G7042_20125	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
G7042_20130	COG1137	ATPase activity
G7042_20135	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
G7042_20145	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
G7042_20150	COG1660	Displays ATPase and GTPase activities
G7042_20155	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
G7042_20175	COG3964	amidohydrolase
G7042_20205	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
G7042_20210	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
G7042_20220	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
G7042_20225	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
G7042_20230	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
G7042_20235	COG0723	plastoquinol--plastocyanin reductase activity
G7042_20240	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
G7042_20245	COG2857	Cytochrome c1
G7042_20250	COG0625	glutathione transferase activity
G7042_20255	COG2969	positive regulation of protein catabolic process
G7042_20260	COG2823	Periplasmic or secreted lipoprotein
G7042_20265	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
G7042_20275	COG3107	peptidoglycan biosynthetic process
G7042_20280	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
G7042_20305	COG1987	bacterial-type flagellum assembly
G7042_20355	COG2249	NAD(P)H dehydrogenase (quinone) activity
G7042_20370	COG1770	oligopeptidase
G7042_20390	COG3714	YhhN family
G7042_20415	COG1301	dicarboxylic acid transport
G7042_20425	COG2095	MarC family integral membrane protein
G7042_20435	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
G7042_20445	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
G7042_20455	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
G7042_20485	COG0742	ribosomal rna small subunit methyltransferase
G7042_20490	COG0552	protein localization to endoplasmic reticulum
G7042_20495	COG2884	Cell division ATP-binding protein ftsE
G7042_20500	COG2177	Part of the ABC transporter FtsEX involved in
G7042_20510	COG0288	reversible hydration of carbon dioxide
G7042_20515	COG2188	Transcriptional regulator
G7042_20520	COG1228	amidohydrolase
G7042_20525	COG0010	Belongs to the arginase family
G7042_20530	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
G7042_20535	COG2986	histidine ammonia-lyase
G7042_20540	COG0387	Pfam Sodium calcium exchanger
G7042_20545	COG2264	protein methyltransferase activity
G7042_20550	COG2200	EAL domain
G7042_20550	COG2199	diguanylate cyclase activity
G7042_20610	COG1077	Cell shape determining protein MreB Mrl
G7042_20615	COG1792	Involved in formation and maintenance of cell shape
G7042_20620	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
G7042_20625	COG0424	maF-like protein
G7042_20630	COG1530	ribonuclease E activity
G7042_20635	COG3164	Protein of unknown function
G7042_20645	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
G7042_20650	COG0312	modulator of DNA gyrase
G7042_20665	COG0477	Major facilitator Superfamily
G7042_20675	COG3437	response regulator, receiver
G7042_20680	COG2205	protein histidine kinase activity
G7042_20680	COG0784	Response regulator, receiver
G7042_20680	COG5002	protein histidine kinase activity
G7042_20685	COG2172	sigma factor antagonist activity
G7042_20690	COG1366	Belongs to the anti-sigma-factor antagonist family
G7042_20700	COG3700	Belongs to the class B bacterial acid phosphatase family
G7042_20710	COG1639	'signal transduction protein
G7042_20735	COG0189	ligase activity
G7042_20740	COG0642	Histidine kinase
G7042_20745	COG0745	RESPONSE REGULATOR receiver
G7042_20780	COG0004	ammonium transporteR
G7042_20785	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
G7042_20795	COG2165	general secretion pathway protein
G7042_20800	COG0084	hydrolase, TatD family'
G7042_20815	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
G7042_20820	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
G7042_20825	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
G7042_20830	COG0813	purine-nucleoside phosphorylase activity
G7042_20840	COG0560	Phosphoserine phosphatase
G7042_20865	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
G7042_20875	COG0776	regulation of translation
G7042_20890	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
G7042_20895	COG0735	belongs to the Fur family
G7042_20915	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
G7042_20920	COG0513	Belongs to the DEAD box helicase family
G7042_20925	COG3022	response to hydroperoxide
G7042_20940	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
G7042_20945	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
G7042_20950	COG0762	integral membrane protein
G7042_20955	COG1872	DUF167
G7042_20970	COG4166	transmembrane transport
G7042_20980	COG0110	maltose O-acetyltransferase activity
G7042_20990	COG1024	Enoyl-CoA hydratase
G7042_21005	COG4221	oxidoreductase activity
G7042_21015	COG2957	Belongs to the agmatine deiminase family
G7042_21030	COG3328	transposase activity
G7042_21125	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
G7042_21130	COG0352	thiamine-phosphate diphosphorylase activity
G7042_21135	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
G7042_21145	COG2022	thiamine diphosphate biosynthetic process
G7042_21175	COG5433	transposase activity
G7042_21180	COG0814	amino acid
G7042_21185	COG3932	Exopolysaccharide synthesis, ExoD
G7042_21235	COG1494	fructose-1,6-bisphosphatase
G7042_21250	COG2959	enzyme of heme biosynthesis
G7042_21260	COG0181	hydroxymethylbilane synthase activity
G7042_21265	COG3072	Adenylate cyclase
G7042_21270	COG0400	carboxylic ester hydrolase activity
G7042_21275	COG1965	Belongs to the frataxin family
G7042_21285	COG0019	diaminopimelate decarboxylase activity
G7042_21290	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
G7042_21305	COG1011	Hydrolase
G7042_21315	COG0668	transmembrane transport
G7042_21325	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
G7042_21330	COG0561	phosphatase activity
G7042_21355	COG0842	Transport permease protein
G7042_21355	COG1129	ABC transporter
G7042_21365	COG1546	Belongs to the CinA family
G7042_21365	COG1058	Belongs to the CinA family
G7042_21370	COG1418	mRNA catabolic process
G7042_21375	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
G7042_21385	COG1522	sequence-specific DNA binding
G7042_21390	COG1368	sulfuric ester hydrolase activity
G7042_21410	COG1285	pathogenesis
G7042_21430	COG4221	oxidoreductase activity
G7042_21450	COG1979	alcohol dehydrogenase
G7042_21460	COG2873	o-acetylhomoserine
G7042_21475	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
G7042_21490	COG5380	lipid catabolic process
G7042_21495	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
G7042_21505	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
G7042_21510	COG2949	membrane
G7042_21525	COG5433	transposase activity
G7042_21560	COG5433	transposase activity
G7042_21610	COG0582	viral genome integration into host DNA
G7042_21625	COG0795	lipopolysaccharide-transporting ATPase activity
G7042_21630	COG0795	lipopolysaccharide-transporting ATPase activity
G7042_21635	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
G7042_21640	COG2927	DNA polymerase III (CHI subunit)
G7042_21655	COG0586	Pfam SNARE associated Golgi protein
G7042_21660	COG1686	Belongs to the peptidase S11 family
G7042_21685	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
G7042_21690	COG0527	aspartate kinase activity
G7042_21695	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
G7042_21705	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
G7042_21710	COG1546	Belongs to the CinA family
G7042_21715	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
G7042_21755	COG1346	cytolysis
G7042_21770	COG0460	homoserine dehydrogenase
G7042_21770	COG0527	aspartate kinase activity
G7042_21775	COG0626	cystathionine gamma-synthase activity
G7042_21790	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
G7042_21795	COG0814	amino acid
G7042_21800	COG1218	3'(2'),5'-bisphosphate nucleotidase
G7042_21805	COG0494	nUDIX hydrolase
G7042_21810	COG1011	Hydrolase
G7042_21815	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
G7042_21830	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
G7042_21840	COG3156	type II secretion system protein K
G7042_21845	COG4795	General secretion pathway protein
G7042_21850	COG2165	general secretion pathway protein
G7042_21860	COG2165	general secretion pathway protein
G7042_21865	COG1459	type II secretion system
G7042_21870	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
G7042_21890	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
G7042_21895	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
G7042_21915	COG0456	acetyltransferase
G7042_21920	COG3133	Outer membrane lipoprotein
G7042_21935	COG2771	luxR family
G7042_21950	COG4776	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction
G7042_21965	COG2213	PTS system mannitol-specific
G7042_21965	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
G7042_21970	COG0246	Mannitol dehydrogenase
G7042_21975	COG3722	fumarate hydratase activity
G7042_21980	COG3263	regulation of cellular component size
G7042_21985	COG0484	heat shock protein binding
G7042_22005	COG1671	Belongs to the UPF0178 family
G7042_22020	COG1988	membrane-bound metal-dependent
G7042_22025	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
G7042_22035	COG0513	Belongs to the DEAD box helicase family
G7042_22060	COG1575	Belongs to the MenA family. Type 1 subfamily
G7042_22065	COG1169	isochorismate synthase
G7042_22070	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
G7042_22075	COG0596	Alpha beta hydrolase
G7042_22080	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
G7042_22090	COG0318	PFAM AMP-dependent synthetase and ligase
G7042_22100	COG5433	transposase activity
G7042_22150	COG0513	Belongs to the DEAD box helicase family
G7042_22170	COG1912	Pfam S-adenosyl-l-methionine hydroxide adenosyltransferase
G7042_22230	COG1280	lysine exporter protein (LysE YggA)
G7042_22235	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
G7042_22250	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
G7042_22280	COG0745	RESPONSE REGULATOR receiver
G7042_22285	COG3104	oligopeptide transport
G7042_22290	COG1210	Utp--glucose-1-phosphate uridylyltransferase
G7042_22295	COG1555	photosystem II stabilization
G7042_22305	COG2350	Protein conserved in bacteria
G7042_22310	COG2917	probably involved in intracellular septation
G7042_22315	COG0076	glutamate decarboxylase activity
G7042_22320	COG1272	protein, Hemolysin III
G7042_22325	COG2985	domain, Protein
G7042_22325	COG0569	domain protein
G7042_22335	COG0835	chemotaxis
G7042_22335	COG0784	Response regulator, receiver
G7042_22340	COG2755	lipolytic protein G-D-S-L family
G7042_22345	COG4181	ATPase activity
G7042_22350	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
G7042_22355	COG1090	epimerase
G7042_22360	COG2200	EAL domain
G7042_22365	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
G7042_22370	COG2234	aminopeptidase activity
G7042_22370	COG4935	Belongs to the peptidase S8 family
G7042_22375	COG0220	tRNA (guanine-N7-)-methyltransferase activity
G7042_22380	COG3171	Protein conserved in bacteria
G7042_22385	COG2066	Belongs to the glutaminase family
G7042_22390	COG2897	thiosulfate sulfurtransferase activity
G7042_22400	COG1132	(ABC) transporter
G7042_22415	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
G7042_22445	COG3076	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome
G7042_22450	COG3300	MHYT domain
G7042_22450	COG5001	Diguanylate cyclase
G7042_22470	COG4628	conserved protein (DUF2132)
G7042_22475	COG0688	phosphatidylethanolamine metabolic process
G7042_22485	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
G7042_22530	COG1278	Cold shock
G7042_22545	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
G7042_22595	COG0848	biopolymer transport protein
G7042_22600	COG0811	peptide transport
G7042_22605	COG0811	peptide transport
G7042_22615	COG4206	TonB-dependent receptor
G7042_22620	COG5433	transposase activity
G7042_22640	COG4239	(ABC) transporter, permease
G7042_22645	COG0747	negative chemotaxis
G7042_22650	COG0444	Belongs to the ABC transporter superfamily
G7042_22655	COG4608	Belongs to the ABC transporter superfamily
G7042_22660	COG2195	Cleaves the N-terminal amino acid of tripeptides
G7042_22680	COG3646	Phage regulatory protein
G7042_22705	COG4790	Type iii secretion
G7042_22710	COG4794	Type iii secretion
G7042_22715	COG4791	protein targeting
G7042_22720	COG4792	protein secretion
G7042_22770	COG1484	DNA-dependent DNA replication
G7042_22865	COG2916	Histone family protein nucleoid-structuring protein H-NS
G7042_22870	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
G7042_22875	COG2361	Protein of unknown function DUF86
G7042_22895	COG1192	Involved in chromosome partitioning
G7042_22940	COG1317	bacterial-type flagellum organization
G7042_23030	COG0457	Tetratricopeptide repeat
G7042_23120	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
G7042_23140	COG1192	Involved in chromosome partitioning
G7042_23190	COG2003	Belongs to the UPF0758 family
G7042_23380	COG2361	Protein of unknown function DUF86
G7042_23400	COG1192	Involved in chromosome partitioning
G7042_23525	COG0630	type IV secretory pathway, VirB11 components, and related ATPases involved in Archaeal flagella biosynthesis
G7042_23540	COG3736	Type IV secretory pathway, component VirB8
G7042_23560	COG3451	type IV secretory pathway VirB4
G7042_23575	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
G7042_23675	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
G7042_23685	COG3093	addiction module antidote protein HigA
G7042_23760	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII