locus-tag	class	description
BHG40_00080	COG3646	Phage regulatory protein
BHG40_00095	COG2195	Cleaves the N-terminal amino acid of tripeptides
BHG40_00100	COG4608	Belongs to the ABC transporter superfamily
BHG40_00105	COG0444	Belongs to the ABC transporter superfamily
BHG40_00110	COG0747	negative chemotaxis
BHG40_00115	COG4239	(ABC) transporter, permease
BHG40_00120	COG4174	ABC transporter (Permease)
BHG40_00130	COG0601	transmembrane transport
BHG40_00135	COG5433	transposase activity
BHG40_00140	COG4206	TonB-dependent receptor
BHG40_00150	COG0811	peptide transport
BHG40_00155	COG0811	peptide transport
BHG40_00160	COG0848	biopolymer transport protein
BHG40_00210	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
BHG40_00225	COG1278	Cold shock
BHG40_00270	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
BHG40_00280	COG0688	phosphatidylethanolamine metabolic process
BHG40_00285	COG4628	conserved protein (DUF2132)
BHG40_00305	COG5001	Diguanylate cyclase
BHG40_00305	COG3300	MHYT domain
BHG40_00310	COG3076	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome
BHG40_00315	COG4412	M6 family metalloprotease domain protein
BHG40_00315	COG3291	Pkd domain containing protein
BHG40_00340	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
BHG40_00345	COG1012	belongs to the aldehyde dehydrogenase family
BHG40_00360	COG1132	(ABC) transporter
BHG40_00370	COG2897	thiosulfate sulfurtransferase activity
BHG40_00375	COG2066	Belongs to the glutaminase family
BHG40_00380	COG3171	Protein conserved in bacteria
BHG40_00385	COG0220	tRNA (guanine-N7-)-methyltransferase activity
BHG40_00390	COG2234	aminopeptidase activity
BHG40_00390	COG4935	Belongs to the peptidase S8 family
BHG40_00395	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BHG40_00400	COG2200	EAL domain
BHG40_00405	COG1090	epimerase
BHG40_00410	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
BHG40_00415	COG4181	ATPase activity
BHG40_00420	COG2755	lipolytic protein G-D-S-L family
BHG40_00425	COG0784	Response regulator, receiver
BHG40_00425	COG0835	chemotaxis
BHG40_00445	COG0076	glutamate decarboxylase activity
BHG40_00450	COG2917	probably involved in intracellular septation
BHG40_00455	COG2350	Protein conserved in bacteria
BHG40_00465	COG1555	photosystem II stabilization
BHG40_00470	COG1210	Utp--glucose-1-phosphate uridylyltransferase
BHG40_00475	COG3104	oligopeptide transport
BHG40_00480	COG2204	response regulator
BHG40_00510	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BHG40_00525	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
BHG40_00530	COG1280	lysine exporter protein (LysE YggA)
BHG40_00590	COG1912	Pfam S-adenosyl-l-methionine hydroxide adenosyltransferase
BHG40_00610	COG0513	Belongs to the DEAD box helicase family
BHG40_00645	COG3385	transposase activity
BHG40_00660	COG5433	transposase activity
BHG40_00700	COG0582	viral genome integration into host DNA
BHG40_00715	COG0795	lipopolysaccharide-transporting ATPase activity
BHG40_00720	COG0795	lipopolysaccharide-transporting ATPase activity
BHG40_00730	COG2927	DNA polymerase III (CHI subunit)
BHG40_00745	COG0586	Pfam SNARE associated Golgi protein
BHG40_00750	COG1686	Belongs to the peptidase S11 family
BHG40_00775	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
BHG40_00780	COG0527	aspartate kinase activity
BHG40_00785	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
BHG40_00795	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
BHG40_00800	COG1546	Belongs to the CinA family
BHG40_00805	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
BHG40_00845	COG1346	cytolysis
BHG40_00860	COG0527	aspartate kinase activity
BHG40_00860	COG0460	homoserine dehydrogenase
BHG40_00880	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BHG40_00885	COG0814	amino acid
BHG40_00890	COG1218	3'(2'),5'-bisphosphate nucleotidase
BHG40_00895	COG0494	nUDIX hydrolase
BHG40_00900	COG1011	Hydrolase
BHG40_00905	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
BHG40_00920	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
BHG40_00930	COG3156	type II secretion system protein K
BHG40_00935	COG4795	General secretion pathway protein
BHG40_00940	COG2165	general secretion pathway protein
BHG40_00950	COG2165	general secretion pathway protein
BHG40_00955	COG1459	type II secretion system
BHG40_00960	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
BHG40_00980	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
BHG40_00985	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
BHG40_01005	COG0456	acetyltransferase
BHG40_01010	COG3133	Outer membrane lipoprotein
BHG40_01025	COG2771	luxR family
BHG40_01040	COG4776	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction
BHG40_01055	COG2213	PTS system mannitol-specific
BHG40_01055	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
BHG40_01060	COG0246	Mannitol dehydrogenase
BHG40_01065	COG3722	fumarate hydratase activity
BHG40_01070	COG3263	regulation of cellular component size
BHG40_01075	COG0484	heat shock protein binding
BHG40_01095	COG1671	Belongs to the UPF0178 family
BHG40_01110	COG1988	membrane-bound metal-dependent
BHG40_01115	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BHG40_01125	COG0513	Belongs to the DEAD box helicase family
BHG40_01150	COG1575	Belongs to the MenA family. Type 1 subfamily
BHG40_01155	COG1169	isochorismate synthase
BHG40_01160	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
BHG40_01165	COG0596	Alpha beta hydrolase
BHG40_01170	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
BHG40_01180	COG0318	PFAM AMP-dependent synthetase and ligase
BHG40_01190	COG5433	transposase activity
BHG40_01225	COG5433	transposase activity
BHG40_01245	COG2949	membrane
BHG40_01260	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
BHG40_01265	COG5380	lipid catabolic process
BHG40_01280	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
BHG40_01290	COG2873	o-acetylhomoserine
BHG40_01300	COG1979	alcohol dehydrogenase
BHG40_01320	COG4221	oxidoreductase activity
BHG40_01340	COG1285	pathogenesis
BHG40_01360	COG1368	sulfuric ester hydrolase activity
BHG40_01365	COG1522	sequence-specific DNA binding
BHG40_01375	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
BHG40_01380	COG1418	mRNA catabolic process
BHG40_01385	COG1546	Belongs to the CinA family
BHG40_01385	COG1058	Belongs to the CinA family
BHG40_01395	COG0842	Transport permease protein
BHG40_01395	COG1129	ABC transporter
BHG40_01420	COG0561	phosphatase activity
BHG40_01425	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
BHG40_01435	COG0668	transmembrane transport
BHG40_01445	COG1011	Hydrolase
BHG40_01460	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
BHG40_01465	COG0019	diaminopimelate decarboxylase activity
BHG40_01470	COG1965	Belongs to the frataxin family
BHG40_01475	COG0400	carboxylic ester hydrolase activity
BHG40_01480	COG3072	Adenylate cyclase
BHG40_01485	COG0181	hydroxymethylbilane synthase activity
BHG40_01495	COG2959	enzyme of heme biosynthesis
BHG40_01510	COG1494	fructose-1,6-bisphosphatase
BHG40_01560	COG3932	Exopolysaccharide synthesis, ExoD
BHG40_01565	COG0814	amino acid
BHG40_01570	COG5433	transposase activity
BHG40_01600	COG2022	thiamine diphosphate biosynthetic process
BHG40_01610	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
BHG40_01615	COG0352	thiamine-phosphate diphosphorylase activity
BHG40_01620	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
BHG40_01670	COG3385	transposase activity
BHG40_01720	COG3328	transposase activity
BHG40_01735	COG2957	Belongs to the agmatine deiminase family
BHG40_01745	COG4221	oxidoreductase activity
BHG40_01760	COG1024	Enoyl-CoA hydratase
BHG40_01770	COG0110	maltose O-acetyltransferase activity
BHG40_01780	COG4166	transmembrane transport
BHG40_01795	COG1872	DUF167
BHG40_01800	COG0762	integral membrane protein
BHG40_01805	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
BHG40_01810	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
BHG40_01825	COG3022	response to hydroperoxide
BHG40_01830	COG0513	Belongs to the DEAD box helicase family
BHG40_01835	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
BHG40_01860	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
BHG40_01870	COG0776	regulation of translation
BHG40_01875	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
BHG40_01900	COG0560	Phosphoserine phosphatase
BHG40_01910	COG0813	purine-nucleoside phosphorylase activity
BHG40_01915	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
BHG40_01920	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
BHG40_01925	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
BHG40_01940	COG0084	hydrolase, TatD family'
BHG40_01955	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
BHG40_01960	COG0004	ammonium transporteR
BHG40_01995	COG0745	RESPONSE REGULATOR receiver
BHG40_02005	COG0189	ligase activity
BHG40_02030	COG1639	'signal transduction protein
BHG40_02040	COG3700	Belongs to the class B bacterial acid phosphatase family
BHG40_02050	COG1366	Belongs to the anti-sigma-factor antagonist family
BHG40_02055	COG2172	sigma factor antagonist activity
BHG40_02060	COG0784	Response regulator, receiver
BHG40_02060	COG2205	protein histidine kinase activity
BHG40_02060	COG5002	protein histidine kinase activity
BHG40_02065	COG3437	response regulator, receiver
BHG40_02075	COG0477	Major facilitator Superfamily
BHG40_02090	COG0312	modulator of DNA gyrase
BHG40_02095	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BHG40_02105	COG3164	Protein of unknown function
BHG40_02110	COG1530	ribonuclease E activity
BHG40_02115	COG0424	maF-like protein
BHG40_02120	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
BHG40_02125	COG1792	Involved in formation and maintenance of cell shape
BHG40_02130	COG1077	Cell shape determining protein MreB Mrl
BHG40_02190	COG2200	EAL domain
BHG40_02190	COG2199	diguanylate cyclase activity
BHG40_02200	COG0387	Pfam Sodium calcium exchanger
BHG40_02205	COG2986	histidine ammonia-lyase
BHG40_02210	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
BHG40_02215	COG0010	Belongs to the arginase family
BHG40_02220	COG1228	amidohydrolase
BHG40_02225	COG2188	Transcriptional regulator
BHG40_02230	COG0288	reversible hydration of carbon dioxide
BHG40_02240	COG2177	Part of the ABC transporter FtsEX involved in
BHG40_02245	COG2884	Cell division ATP-binding protein ftsE
BHG40_02250	COG0552	protein localization to endoplasmic reticulum
BHG40_02255	COG0742	ribosomal rna small subunit methyltransferase
BHG40_02280	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BHG40_02285	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
BHG40_02295	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
BHG40_02305	COG2095	MarC family integral membrane protein
BHG40_02315	COG1301	dicarboxylic acid transport
BHG40_02340	COG3714	YhhN family
BHG40_02370	COG2249	NAD(P)H dehydrogenase (quinone) activity
BHG40_02440	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
BHG40_02445	COG3107	peptidoglycan biosynthetic process
BHG40_02455	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
BHG40_02460	COG2823	Periplasmic or secreted lipoprotein
BHG40_02465	COG2969	positive regulation of protein catabolic process
BHG40_02470	COG0625	glutathione transferase activity
BHG40_02475	COG2857	Cytochrome c1
BHG40_02480	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
BHG40_02485	COG0723	plastoquinol--plastocyanin reductase activity
BHG40_02490	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
BHG40_02495	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
BHG40_02500	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
BHG40_02515	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BHG40_02545	COG3964	amidohydrolase
BHG40_02565	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
BHG40_02570	COG1660	Displays ATPase and GTPase activities
BHG40_02575	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BHG40_02590	COG1137	ATPase activity
BHG40_02595	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
BHG40_02600	COG3117	lipopolysaccharide transmembrane transporter activity
BHG40_02605	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
BHG40_02610	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
BHG40_02610	COG0517	IMP dehydrogenase activity
BHG40_02615	COG1127	ABC transporter
BHG40_02620	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
BHG40_02625	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
BHG40_02630	COG2854	intermembrane phospholipid transfer
BHG40_02640	COG5007	Belongs to the BolA IbaG family
BHG40_02645	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
BHG40_02650	COG0312	modulator of DNA gyrase
BHG40_02655	COG3028	Belongs to the UPF0307 family
BHG40_02665	COG2926	Belongs to the UPF0265 family
BHG40_02695	COG1396	sequence-specific DNA binding
BHG40_02700	COG3135	benzoate transporter
BHG40_02730	COG3047	cAMP biosynthetic process
BHG40_02790	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
BHG40_02795	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
BHG40_02800	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
BHG40_02805	COG0049	tRNA binding
BHG40_02815	COG2168	tRNA wobble position uridine thiolation
BHG40_02820	COG2923	Belongs to the DsrF TusC family
BHG40_02835	COG2964	Protein conserved in bacteria
BHG40_02840	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
BHG40_02845	COG0085	RNA polymerase activity
BHG40_02850	COG0222	ribosome binding
BHG40_02855	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
BHG40_02860	COG0081	regulation of translation
BHG40_02865	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
BHG40_02870	COG0250	Participates in transcription elongation, termination and antitermination
BHG40_02875	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
BHG40_02885	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
BHG40_02910	COG0812	UDP-N-acetylmuramate dehydrogenase activity
BHG40_02915	COG0569	domain protein
BHG40_02920	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
BHG40_02925	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
BHG40_02930	COG3005	denitrification pathway
BHG40_02935	COG0243	molybdopterin cofactor binding
BHG40_02945	COG2205	protein histidine kinase activity
BHG40_02950	COG0745	RESPONSE REGULATOR receiver
BHG40_02965	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
BHG40_02970	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
BHG40_02980	COG2204	response regulator
BHG40_02990	COG2205	protein histidine kinase activity
BHG40_03000	COG1028	Short-chain dehydrogenase reductase Sdr
BHG40_03005	COG0516	GMP reductase activity
BHG40_03005	COG0517	IMP dehydrogenase activity
BHG40_03010	COG5413	integral membrane protein
BHG40_03020	COG1522	sequence-specific DNA binding
BHG40_03025	COG2502	aspartate--ammonia ligase
BHG40_03030	COG0542	response to heat
BHG40_03040	COG0564	pseudouridine synthase activity
BHG40_03045	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BHG40_03050	COG0446	pyridine nucleotide-disulphide oxidoreductase
BHG40_03060	COG3681	Belongs to the UPF0597 family
BHG40_03065	COG2964	Protein conserved in bacteria
BHG40_03075	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
BHG40_03080	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
BHG40_03085	COG1979	alcohol dehydrogenase
BHG40_03090	COG2207	Transcriptional regulator
BHG40_03095	COG3040	lipid binding
BHG40_03105	COG0688	phosphatidylethanolamine metabolic process
BHG40_03120	COG0540	Belongs to the ATCase OTCase family
BHG40_03125	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
BHG40_03135	COG1288	antiporter activity
BHG40_03140	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
BHG40_03170	COG3328	transposase activity
BHG40_03180	COG4211	Belongs to the binding-protein-dependent transport system permease family
BHG40_03195	COG3250	beta-galactosidase activity
BHG40_03200	COG1609	Transcriptional regulator
BHG40_03205	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
BHG40_03215	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
BHG40_03220	COG2017	converts alpha-aldose to the beta-anomer
BHG40_03225	COG0667	Aldo Keto reductase
BHG40_03230	COG1968	undecaprenyl-diphosphatase activity
BHG40_03240	COG1595	DNA-templated transcription, initiation
BHG40_03250	COG0018	arginyl-trna synthetase
BHG40_03260	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
BHG40_03265	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
BHG40_03280	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BHG40_03290	COG5433	transposase activity
BHG40_03295	COG2391	methyltransferase activity
BHG40_03335	COG0210	DNA helicase
BHG40_03360	COG0583	DNA-binding transcription factor activity
BHG40_03380	COG1262	PFAM Formylglycine-generating sulfatase enzyme
BHG40_03385	COG0385	Bile acid
BHG40_03440	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
BHG40_03455	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
BHG40_03460	COG3074	FtsZ-dependent cytokinesis
BHG40_03470	COG1045	serine acetyltransferase
BHG40_03480	COG0745	RESPONSE REGULATOR receiver
BHG40_03485	COG2205	protein histidine kinase activity
BHG40_03490	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
BHG40_03495	COG0534	Mate efflux family protein
BHG40_03510	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
BHG40_03515	COG2937	Belongs to the GPAT DAPAT family
BHG40_03520	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
BHG40_03525	COG3161	chorismate lyase activity
BHG40_03530	COG1580	Controls the rotational direction of flagella during chemotaxis
BHG40_03550	COG1609	Transcriptional regulator
BHG40_03555	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BHG40_03570	COG1519	Transferase
BHG40_03575	COG0859	PFAM glycosyl transferase family 9
BHG40_03580	COG0463	Glycosyl transferase, family 2
BHG40_03585	COG0859	PFAM glycosyl transferase family 9
BHG40_03590	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
BHG40_03595	COG2990	Protein conserved in bacteria
BHG40_03600	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
BHG40_03610	COG0267	Belongs to the bacterial ribosomal protein bL33 family
BHG40_03615	COG2003	Belongs to the UPF0758 family
BHG40_03620	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
BHG40_03625	COG0756	dUTP diphosphatase activity
BHG40_03630	COG1309	transcriptional regulator
BHG40_03635	COG0668	transmembrane transport
BHG40_03645	COG0166	Belongs to the GPI family
BHG40_03650	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
BHG40_03655	COG0583	DNA-binding transcription factor activity
BHG40_03700	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
BHG40_03705	COG4206	TonB-dependent receptor
BHG40_03710	COG0583	DNA-binding transcription factor activity
BHG40_03725	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
BHG40_03730	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
BHG40_03735	COG2223	nitrite transmembrane transporter activity
BHG40_03740	COG3279	Response regulator of the LytR AlgR family
BHG40_03745	COG3275	phosphorelay sensor kinase activity
BHG40_03755	COG2205	protein histidine kinase activity
BHG40_03755	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BHG40_03775	COG5433	transposase activity
BHG40_03790	COG5433	transposase activity
BHG40_03800	COG5433	transposase activity
BHG40_03825	COG2081	HI0933 family
BHG40_03830	COG1528	Iron-storage protein
BHG40_03840	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
BHG40_03845	COG0589	response to stress
BHG40_03880	COG3642	lipopolysaccharide core region biosynthetic process
BHG40_03885	COG0859	PFAM glycosyl transferase family 9
BHG40_03895	COG0194	GDP metabolic process
BHG40_03900	COG1758	RNA polymerase activity
BHG40_03905	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
BHG40_03910	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BHG40_03915	COG2267	carboxylic ester hydrolase activity
BHG40_03950	COG1309	transcriptional regulator
BHG40_03955	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BHG40_03960	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BHG40_03965	COG4191	Histidine kinase
BHG40_03965	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BHG40_03970	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BHG40_03990	COG2205	protein histidine kinase activity
BHG40_03995	COG0745	RESPONSE REGULATOR receiver
BHG40_04000	COG2814	Major facilitator Superfamily
BHG40_04015	COG3977	Valine--pyruvate aminotransferase
BHG40_04035	COG0071	Belongs to the small heat shock protein (HSP20) family
BHG40_04040	COG0071	Belongs to the small heat shock protein (HSP20) family
BHG40_04045	COG2378	regulation of single-species biofilm formation
BHG40_04060	COG0187	DNA topoisomerase II activity
BHG40_04070	COG0592	DNA-directed DNA polymerase activity
BHG40_04075	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
BHG40_04095	COG0230	Belongs to the bacterial ribosomal protein bL34 family
BHG40_04100	COG0594	ribonuclease P activity
BHG40_04105	COG0706	membrane insertase activity
BHG40_04110	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
BHG40_04125	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BHG40_04155	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BHG40_04160	COG4605	iron ion homeostasis
BHG40_04165	COG4604	ABC transporter, ATP-binding protein
BHG40_04170	COG4607	ABC-type enterochelin transport system periplasmic component
BHG40_04175	COG4774	siderophore transport
BHG40_04185	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BHG40_04190	COG1120	ATPase activity
BHG40_04195	COG4615	Cyclic peptide transporter
BHG40_04200	COG4774	siderophore transport
BHG40_04205	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
BHG40_04210	COG0445	tRNA wobble uridine modification
BHG40_04215	COG0357	Ribosomal RNA small subunit methyltransferase G
BHG40_04220	COG1192	Involved in chromosome partitioning
BHG40_04225	COG1475	DNA binding
BHG40_04235	COG0356	it plays a direct role in the translocation of protons across the membrane
BHG40_04245	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
BHG40_04255	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
BHG40_04260	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
BHG40_04265	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
BHG40_04270	COG0355	proton-transporting ATP synthase activity, rotational mechanism
BHG40_04275	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
BHG40_04280	COG4452	Inner membrane protein CreD
BHG40_04290	COG2205	protein histidine kinase activity
BHG40_04295	COG0745	RESPONSE REGULATOR receiver
BHG40_04300	COG1349	DNA-binding transcription factor activity
BHG40_04305	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
BHG40_04310	COG2771	luxR family
BHG40_04320	COG0811	peptide transport
BHG40_04325	COG0811	peptide transport
BHG40_04330	COG0848	biopolymer transport protein
BHG40_04335	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
BHG40_04375	COG0402	S-adenosylhomocysteine deaminase activity
BHG40_04380	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
BHG40_04390	COG3165	ubiquinone biosynthetic process from chorismate
BHG40_04395	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
BHG40_04405	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
BHG40_04410	COG0805	protein transport
BHG40_04415	COG0084	hydrolase, TatD family'
BHG40_04435	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BHG40_04440	COG0742	ribosomal rna small subunit methyltransferase
BHG40_04450	COG0248	Ppx GppA phosphatase
BHG40_04455	COG0513	Belongs to the DEAD box helicase family
BHG40_04460	COG3118	belongs to the thioredoxin family
BHG40_04465	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
BHG40_04475	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
BHG40_04500	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BHG40_04530	COG0559	Belongs to the binding-protein-dependent transport system permease family
BHG40_04540	COG1609	Transcriptional regulator
BHG40_04570	COG3328	transposase activity
BHG40_04600	COG2199	diguanylate cyclase activity
BHG40_04600	COG2200	EAL domain
BHG40_04600	COG2202	Pas domain
BHG40_04615	COG0814	amino acid
BHG40_04620	COG0348	domain, Protein
BHG40_04630	COG0446	pyridine nucleotide-disulphide oxidoreductase
BHG40_04640	COG3604	Transcriptional regulator
BHG40_04645	COG2188	Transcriptional regulator
BHG40_04665	COG0751	glycine-tRNA ligase activity
BHG40_04670	COG0752	glycyl-tRNA synthetase alpha subunit
BHG40_04680	COG2885	chlorophyll binding
BHG40_04685	COG0251	oxidation-reduction process
BHG40_04690	COG0425	Belongs to the sulfur carrier protein TusA family
BHG40_04705	COG2205	protein histidine kinase activity
BHG40_04710	COG0745	RESPONSE REGULATOR receiver
BHG40_04715	COG0183	Belongs to the thiolase family
BHG40_04720	COG1250	3-hydroxyacyl-CoA dehydrogenase
BHG40_04720	COG1024	Enoyl-CoA hydratase
BHG40_04725	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BHG40_04735	COG1739	Uncharacterized protein family UPF0029
BHG40_04740	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
BHG40_04745	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
BHG40_04775	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
BHG40_04780	COG2166	iron-sulfur cluster assembly
BHG40_04785	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
BHG40_04790	COG0210	DNA helicase
BHG40_04805	COG1063	alcohol dehydrogenase
BHG40_04820	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BHG40_04855	COG1561	YicC-like family, N-terminal region
BHG40_04865	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
BHG40_04880	COG5001	Diguanylate cyclase
BHG40_04880	COG2203	Gaf domain
BHG40_04880	COG3706	GGDEF domain
BHG40_04880	COG4251	negative regulation of phosphorylation
BHG40_04885	COG3084	Protein conserved in bacteria
BHG40_04895	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
BHG40_04900	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
BHG40_04905	COG3639	organic phosphonate transmembrane transporter activity
BHG40_04910	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
BHG40_04915	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
BHG40_04925	COG1335	isochorismatase
BHG40_04935	COG1683	Conserved Protein
BHG40_04945	COG0606	chelatase, subunit chli
BHG40_04955	COG3978	acetolactate synthase activity
BHG40_04960	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BHG40_04965	COG0129	dihydroxy-acid dehydratase activity
BHG40_04985	COG1309	transcriptional regulator
BHG40_04995	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
BHG40_05000	COG0254	rRNA binding
BHG40_05005	COG0702	epimerase
BHG40_05010	COG0281	malic enzyme
BHG40_05020	COG2205	protein histidine kinase activity
BHG40_05025	COG0745	RESPONSE REGULATOR receiver
BHG40_05030	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
BHG40_05065	COG4310	Domain of unknown function (DUF2172)
BHG40_05075	COG5433	transposase activity
BHG40_05095	COG2089	acid synthase
BHG40_05105	COG1083	cytidylyl-transferase
BHG40_05125	COG0318	PFAM AMP-dependent synthetase and ligase
BHG40_05150	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
BHG40_05155	COG1086	Polysaccharide biosynthesis protein
BHG40_05160	COG0366	Alpha amylase catalytic
BHG40_05175	COG0443	Heat shock 70 kDa protein
BHG40_05180	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BHG40_05195	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
BHG40_05200	COG0174	glutamine synthetase
BHG40_05220	COG3842	ATPase activity
BHG40_05225	COG1176	ABC-type spermidine putrescine transport system, permease component I
BHG40_05230	COG1177	transmembrane transport
BHG40_05235	COG2258	MOSC domain
BHG40_05255	COG2050	protein possibly involved in aromatic compounds catabolism
BHG40_05260	COG0514	ATP-dependent DNA helicase (RecQ)
BHG40_05270	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
BHG40_05280	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
BHG40_05285	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
BHG40_05295	COG2239	Acts as a magnesium transporter
BHG40_05300	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
BHG40_05300	COG1648	precorrin-2 dehydrogenase activity
BHG40_05305	COG2116	formate transmembrane transporter activity
BHG40_05310	COG2146	nitrite reductase [NAD(P)H] activity
BHG40_05325	COG1280	lysine exporter protein (LysE YggA)
BHG40_05335	COG2962	Rard protein
BHG40_05345	COG1012	belongs to the aldehyde dehydrogenase family
BHG40_05365	COG0519	Catalyzes the synthesis of GMP from XMP
BHG40_05365	COG0518	GMP synthase (glutamine-hydrolyzing) activity
BHG40_05370	COG0686	Belongs to the AlaDH PNT family
BHG40_05375	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BHG40_05395	COG1322	Protein conserved in bacteria
BHG40_05400	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
BHG40_05405	COG0569	domain protein
BHG40_05410	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
BHG40_05410	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
BHG40_05415	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
BHG40_05420	COG0242	peptide deformylase activity
BHG40_05425	COG1652	LysM domain
BHG40_05430	COG0758	DNA mediated transformation
BHG40_05435	COG2922	Belongs to the Smg family
BHG40_05440	COG0551	DNA topoisomerase type I activity
BHG40_05450	COG0009	L-threonylcarbamoyladenylate synthase
BHG40_05455	COG0408	coproporphyrinogen oxidase activity
BHG40_05460	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
BHG40_05470	COG0218	Necessary for normal cell division and for the maintenance of normal septation
BHG40_05480	COG3078	GTPase activator activity
BHG40_05490	COG0635	Involved in the biosynthesis of porphyrin-containing compound
BHG40_05495	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
BHG40_05500	COG2204	response regulator
BHG40_05505	COG3852	Histidine kinase
BHG40_05515	COG0174	glutamine synthetase
BHG40_05525	COG1295	ribonuclease BN
BHG40_05530	COG1490	D-aminoacyl-tRNA deacylase activity
BHG40_05540	COG0456	acetyltransferase
BHG40_05550	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
BHG40_05555	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BHG40_05560	COG2610	gluconate transmembrane transporter activity
BHG40_05565	COG3265	gluconokinase activity
BHG40_05570	COG0129	dihydroxy-acid dehydratase activity
BHG40_05575	COG0800	Aldolase
BHG40_05585	COG1609	Transcriptional regulator
BHG40_05595	COG4942	peptidase
BHG40_05600	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
BHG40_05605	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BHG40_05610	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
BHG40_05615	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
BHG40_05620	COG0316	Belongs to the HesB IscA family
BHG40_05620	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
BHG40_05625	COG1040	competence protein
BHG40_05630	COG0596	Alpha beta hydrolase
BHG40_05650	COG2183	response to ionizing radiation
BHG40_05655	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
BHG40_05660	COG0745	RESPONSE REGULATOR receiver
BHG40_05675	COG0051	transcription antitermination factor activity, RNA binding
BHG40_05680	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
BHG40_05685	COG0088	Forms part of the polypeptide exit tunnel
BHG40_05690	COG0089	rRNA binding
BHG40_05695	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
BHG40_05700	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
BHG40_05705	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
BHG40_05710	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
BHG40_05715	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
BHG40_05720	COG0255	Belongs to the universal ribosomal protein uL29 family
BHG40_05725	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
BHG40_05730	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
BHG40_05735	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
BHG40_05740	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
BHG40_05745	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
BHG40_05750	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
BHG40_05755	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
BHG40_05760	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
BHG40_05765	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
BHG40_05770	COG1841	ribosomal large subunit assembly
BHG40_05775	COG0200	Binds to the 23S rRNA
BHG40_05780	COG0201	protein transport
BHG40_05785	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
BHG40_05790	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
BHG40_05795	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
BHG40_05800	COG0202	RNA polymerase activity
BHG40_05805	COG0203	ribosomal protein L17
BHG40_05850	COG2252	PERMEase
BHG40_05855	COG2376	Dihydroxyacetone kinase
BHG40_05860	COG1461	Dihydroxyacetone kinase
BHG40_05865	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
BHG40_05865	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
BHG40_05865	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
BHG40_05875	COG3284	Transcriptional regulator
BHG40_05880	COG0628	permease
BHG40_05885	COG0494	nUDIX hydrolase
BHG40_05910	COG0753	catalase activity
BHG40_05915	COG1247	-acetyltransferase
BHG40_05935	COG2199	diguanylate cyclase activity
BHG40_05935	COG2203	Gaf domain
BHG40_05945	COG3842	ATPase activity
BHG40_05955	COG1176	ABC-type spermidine putrescine transport system, permease component I
BHG40_05980	COG0583	DNA-binding transcription factor activity
BHG40_05990	COG1741	Belongs to the pirin family
BHG40_05995	COG2259	Doxx family
BHG40_06000	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
BHG40_06005	COG1074	ATP-dependent DNA helicase activity
BHG40_06010	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
BHG40_06025	COG0346	lactoylglutathione lyase activity
BHG40_06035	COG5433	transposase activity
BHG40_06055	COG0347	Belongs to the P(II) protein family
BHG40_06060	COG0745	RESPONSE REGULATOR receiver
BHG40_06060	COG3706	GGDEF domain
BHG40_06070	COG0840	transmembrane signaling receptor activity
BHG40_06075	COG2205	protein histidine kinase activity
BHG40_06080	COG3706	GGDEF domain
BHG40_06090	COG1278	Cold shock
BHG40_06100	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
BHG40_06105	COG2197	response regulator
BHG40_06145	COG2204	response regulator
BHG40_06150	COG1677	Flagellar hook-basal body complex protein FliE
BHG40_06160	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
BHG40_06185	COG2747	anti-sigma28 factor FlgM
BHG40_06195	COG1815	bacterial-type flagellum-dependent cell motility
BHG40_06200	COG1558	bacterial-type flagellum-dependent cell motility
BHG40_06205	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
BHG40_06210	COG1749	Flagellar hook protein flgE
BHG40_06215	COG4786	Flagellar basal body rod
BHG40_06220	COG4786	Flagellar basal body rod
BHG40_06225	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
BHG40_06230	COG1706	bacterial-type flagellum-dependent cell motility
BHG40_06240	COG1256	bacterial-type flagellum assembly
BHG40_06240	COG4786	Flagellar basal body rod
BHG40_06260	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
BHG40_06275	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
BHG40_06300	COG1191	sigma factor activity
BHG40_06305	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
BHG40_06310	COG1360	Flagellar Motor Protein
BHG40_06320	COG0741	lytic transglycosylase activity
BHG40_06320	COG1388	LysM domain
BHG40_06330	COG2001	Belongs to the MraZ family
BHG40_06335	COG0275	rRNA processing
BHG40_06340	COG3116	cell division
BHG40_06345	COG0768	penicillin binding
BHG40_06355	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
BHG40_06360	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
BHG40_06365	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
BHG40_06370	COG0772	Belongs to the SEDS family
BHG40_06375	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
BHG40_06380	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
BHG40_06385	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
BHG40_06390	COG0849	cell division
BHG40_06395	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
BHG40_06400	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
BHG40_06410	COG0653	protein targeting
BHG40_06420	COG0494	nUDIX hydrolase
BHG40_06425	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
BHG40_06430	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
BHG40_06440	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
BHG40_06450	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
BHG40_06485	COG2186	Transcriptional regulator
BHG40_06490	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
BHG40_06495	COG0508	dehydrogenase complex catalyzes the overall conversion of
BHG40_06500	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BHG40_06505	COG5001	Diguanylate cyclase
BHG40_06505	COG5002	protein histidine kinase activity
BHG40_06505	COG3447	MASE1 domain protein
BHG40_06515	COG0840	transmembrane signaling receptor activity
BHG40_06520	COG0840	transmembrane signaling receptor activity
BHG40_06530	COG1049	propionate catabolic process, 2-methylcitrate cycle
BHG40_06535	COG2200	EAL domain
BHG40_06540	COG1028	Short-chain dehydrogenase reductase Sdr
BHG40_06545	COG0583	DNA-binding transcription factor activity
BHG40_06555	COG1280	lysine exporter protein (LysE YggA)
BHG40_06565	COG0523	cobalamin synthesis protein
BHG40_06585	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
BHG40_06590	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
BHG40_06720	COG0784	Response regulator, receiver
BHG40_06720	COG0835	chemotaxis
BHG40_06730	COG1444	tRNA N-acetyltransferase activity
BHG40_06755	COG1803	Methylglyoxal synthase
BHG40_06770	COG0252	asparaginase activity
BHG40_06780	COG1609	Transcriptional regulator
BHG40_06790	COG1940	carbohydrate kinase activity
BHG40_06795	COG1447	Phosphotransferase system cellobiose-specific component IIA
BHG40_06800	COG2723	6-phospho-beta-galactosidase activity
BHG40_06805	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BHG40_06805	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BHG40_06810	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BHG40_06815	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BHG40_06830	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BHG40_06830	COG1263	PTS System
BHG40_06835	COG0366	Alpha amylase catalytic
BHG40_06840	COG0110	maltose O-acetyltransferase activity
BHG40_06850	COG1757	Na H antiporter
BHG40_06885	COG0297	glycogen (starch) synthase activity
BHG40_06890	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
BHG40_06895	COG2813	Specifically methylates the guanine in position
BHG40_06900	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BHG40_06915	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BHG40_06925	COG2995	paraquat-inducible protein a
BHG40_06930	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
BHG40_06930	COG3008	intermembrane lipid transfer
BHG40_06935	COG3009	Protein conserved in bacteria
BHG40_06950	COG3240	lipase activity
BHG40_06955	COG3111	PFAM Bacterial OB fold (BOF) protein
BHG40_06965	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
BHG40_06970	COG1194	a g-specific adenine glycosylase
BHG40_06980	COG3409	Peptidoglycan-binding domain 1 protein
BHG40_06980	COG3267	Type II secretory pathway component ExeA
BHG40_06985	COG0617	tRNA 3'-terminal CCA addition
BHG40_06990	COG0306	phosphate transporter
BHG40_06995	COG1392	Phosphate transport regulator
BHG40_07010	COG1560	Kdo2-lipid A biosynthetic process
BHG40_07015	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
BHG40_07015	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
BHG40_07020	COG1538	Outer membrane efflux protein
BHG40_07025	COG0494	nUDIX hydrolase
BHG40_07030	COG3151	Protein conserved in bacteria
BHG40_07040	COG3150	esterase
BHG40_07045	COG1051	belongs to the nudix hydrolase family
BHG40_07055	COG0187	DNA topoisomerase II activity
BHG40_07125	COG2259	Doxx family
BHG40_07130	COG3118	belongs to the thioredoxin family
BHG40_07150	COG0204	Acyl-transferase
BHG40_07170	COG2827	Endonuclease containing a URI domain
BHG40_07185	COG1573	uracil-dna glycosylase
BHG40_07195	COG0583	DNA-binding transcription factor activity
BHG40_07200	COG1108	ABC-type Mn2 Zn2 transport systems permease components
BHG40_07205	COG1121	(ABC) transporter
BHG40_07210	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
BHG40_07230	COG0739	heme binding
BHG40_07240	COG3068	Protein conserved in bacteria
BHG40_07260	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
BHG40_07280	COG0798	PFAM Bile acid sodium symporter
BHG40_07285	COG1393	Belongs to the ArsC family
BHG40_07290	COG2072	flavoprotein involved in K transport
BHG40_07300	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
BHG40_07310	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
BHG40_07315	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
BHG40_07325	COG0137	argininosuccinate synthase activity
BHG40_07330	COG0165	Argininosuccinate lyase
BHG40_07335	COG0583	DNA-binding transcription factor activity
BHG40_07345	COG1942	4-Oxalocrotonate Tautomerase
BHG40_07375	COG0110	maltose O-acetyltransferase activity
BHG40_07380	COG3174	membrane
BHG40_07385	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
BHG40_07395	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
BHG40_07405	COG4208	sulfate ABC transporter
BHG40_07410	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
BHG40_07415	COG0583	DNA-binding transcription factor activity
BHG40_07420	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
BHG40_07425	COG0765	amino acid transport
BHG40_07435	COG1126	abc transporter atp-binding protein
BHG40_07440	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BHG40_07445	COG3397	chitin binding
BHG40_07450	COG0840	transmembrane signaling receptor activity
BHG40_07485	COG0726	polysaccharide deacetylase
BHG40_07485	COG1649	PFAM Uncharacterised BCR, COG1649
BHG40_07490	COG1215	transferase activity, transferring glycosyl groups
BHG40_07525	COG1328	CTP reductase activity
BHG40_07550	COG1448	Aminotransferase
BHG40_07590	COG0513	Belongs to the DEAD box helicase family
BHG40_07605	COG3568	Endonuclease Exonuclease Phosphatase
BHG40_07610	COG0840	transmembrane signaling receptor activity
BHG40_07625	COG3112	Uncharacterised protein family (UPF0231)
BHG40_07630	COG3835	regulator
BHG40_07635	COG2610	gluconate transmembrane transporter activity
BHG40_07640	COG1929	Belongs to the glycerate kinase type-1 family
BHG40_07660	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BHG40_07675	COG0347	Belongs to the P(II) protein family
BHG40_07680	COG1840	ABC-type Fe3 transport system, periplasmic component
BHG40_07690	COG3842	ATPase activity
BHG40_07695	COG2837	iron assimilation
BHG40_07700	COG1438	arginine binding
BHG40_07705	COG1126	abc transporter atp-binding protein
BHG40_07710	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BHG40_07715	COG4215	(ABC) transporter
BHG40_07720	COG4160	amino acid transport
BHG40_07725	COG0039	L-malate dehydrogenase activity
BHG40_07730	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
BHG40_07735	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
BHG40_07735	COG1017	nitric oxide dioxygenase activity
BHG40_07740	COG1959	2 iron, 2 sulfur cluster binding
BHG40_07745	COG4536	flavin adenine dinucleotide binding
BHG40_07750	COG4137	Cytochrome C assembly protein
BHG40_07755	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
BHG40_07760	COG0228	four-way junction DNA binding
BHG40_07765	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
BHG40_07770	COG0336	Belongs to the RNA methyltransferase TrmD family
BHG40_07775	COG0335	large ribosomal subunit rRNA binding
BHG40_07785	COG3066	DNA modification
BHG40_07790	COG1051	belongs to the nudix hydrolase family
BHG40_07800	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
BHG40_07805	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
BHG40_07810	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
BHG40_07820	COG0583	DNA-binding transcription factor activity
BHG40_07825	COG0640	Transcriptional regulator
BHG40_07830	COG0268	Binds directly to 16S ribosomal RNA
BHG40_07835	COG0728	peptidoglycan biosynthetic process
BHG40_07840	COG0196	riboflavin kinase activity
BHG40_07845	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
BHG40_07850	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
BHG40_07855	COG1047	Peptidyl-prolyl cis-trans
BHG40_07860	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
BHG40_07865	COG4968	Prepilin-type N-terminal cleavage methylation domain
BHG40_07900	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BHG40_07900	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
BHG40_07915	COG1854	S-ribosylhomocysteine lyase activity
BHG40_07920	COG3706	GGDEF domain
BHG40_07925	COG0557	exoribonuclease II activity
BHG40_07930	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BHG40_07940	COG2153	protein acetylation
BHG40_07960	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
BHG40_07965	COG1914	H( )-stimulated, divalent metal cation uptake system
BHG40_07970	COG0360	Binds together with S18 to 16S ribosomal RNA
BHG40_07975	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
BHG40_07980	COG0359	binds to the 23S rRNA
BHG40_08005	COG1064	alcohol dehydrogenase
BHG40_08010	COG1238	metal cluster binding
BHG40_08015	COG0612	Peptidase, M16
BHG40_08020	COG2918	glutathione biosynthetic process
BHG40_08030	COG1022	Amp-dependent synthetase and ligase
BHG40_08040	COG0456	acetyltransferase
BHG40_08050	COG0714	Associated with various cellular activities
BHG40_08075	COG3706	GGDEF domain
BHG40_08075	COG0745	RESPONSE REGULATOR receiver
BHG40_08080	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
BHG40_08090	COG1902	pentaerythritol trinitrate reductase activity
BHG40_08100	COG0442	prolyl-tRNA aminoacylation
BHG40_08110	COG0632	four-way junction helicase activity
BHG40_08115	COG2255	four-way junction helicase activity
BHG40_08120	COG1271	oxidase subunit
BHG40_08125	COG1294	oxidase, subunit
BHG40_08130	COG4890	Cyd operon protein YbgT
BHG40_08135	COG3790	cyd operon protein YbgE
BHG40_08140	COG0824	Thioesterase
BHG40_08145	COG0811	peptide transport
BHG40_08160	COG0823	Involved in the tonB-independent uptake of proteins
BHG40_08165	COG2885	chlorophyll binding
BHG40_08170	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
BHG40_08235	COG0840	transmembrane signaling receptor activity
BHG40_08240	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
BHG40_08245	COG0676	glucose-6-phosphate 1-epimerase activity
BHG40_08250	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
BHG40_08255	COG1640	4-alpha-glucanotransferase
BHG40_08260	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
BHG40_08280	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BHG40_08285	COG4991	sh3 domain protein
BHG40_08290	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
BHG40_08290	COG0506	proline dehydrogenase activity
BHG40_08290	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
BHG40_08300	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
BHG40_08305	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
BHG40_08310	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
BHG40_08315	COG0163	prenyltransferase activity
BHG40_08330	COG1131	(ABC) transporter
BHG40_08335	COG0842	Transport permease protein
BHG40_08345	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
BHG40_08350	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
BHG40_08355	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
BHG40_08360	COG0617	tRNA 3'-terminal CCA addition
BHG40_08365	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
BHG40_08370	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
BHG40_08375	COG1489	DNA binding
BHG40_08385	COG1643	Atp-dependent helicase
BHG40_08390	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BHG40_08395	COG0346	lactoylglutathione lyase activity
BHG40_08405	COG2076	Multidrug Resistance protein
BHG40_08410	COG0583	DNA-binding transcription factor activity
BHG40_08415	COG0784	Response regulator, receiver
BHG40_08415	COG3437	response regulator, receiver
BHG40_08425	COG0671	phosphoesterase, PA-phosphatase related
BHG40_08440	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
BHG40_08445	COG0038	chloride channel
BHG40_08455	COG0316	Belongs to the HesB IscA family
BHG40_08485	COG2816	NAD+ diphosphatase activity
BHG40_08490	COG2205	protein histidine kinase activity
BHG40_08495	COG0745	RESPONSE REGULATOR receiver
BHG40_08500	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BHG40_08520	COG1505	serine-type exopeptidase activity
BHG40_08525	COG2982	Protein involved in outer membrane biogenesis
BHG40_08535	COG1028	Short-chain dehydrogenase reductase Sdr
BHG40_08565	COG1349	DNA-binding transcription factor activity
BHG40_08570	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
BHG40_08590	COG2130	NADP-dependent
BHG40_08595	COG1764	response to oxidative stress
BHG40_08600	COG1846	Transcriptional regulator
BHG40_08630	COG0561	phosphatase activity
BHG40_08655	COG0733	neurotransmitter:sodium symporter activity
BHG40_08680	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BHG40_08695	COG1794	racemase activity, acting on amino acids and derivatives
BHG40_08705	COG2731	YhcH YjgK YiaL family protein
BHG40_08715	COG0668	transmembrane transport
BHG40_08720	COG1376	ErfK ybiS ycfS ynhG family protein
BHG40_08725	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BHG40_08755	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
BHG40_08765	COG0488	(ABC) transporter
BHG40_08770	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
BHG40_08770	COG0517	IMP dehydrogenase activity
BHG40_08775	COG1585	Membrane protein implicated in regulation of membrane protease activity
BHG40_08780	COG0330	HflC and HflK could
BHG40_08785	COG1648	precorrin-2 dehydrogenase activity
BHG40_08785	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
BHG40_08790	COG0175	sulfate reduction
BHG40_08795	COG2895	sulfate adenylyltransferase (ATP) activity
BHG40_08800	COG0471	metal ion transport
BHG40_08800	COG3273	potassium ion transport
BHG40_08805	COG0529	Catalyzes the synthesis of activated sulfate
BHG40_08810	COG5433	transposase activity
BHG40_08820	COG3328	transposase activity
BHG40_08870	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
BHG40_08895	COG1940	carbohydrate kinase activity
BHG40_08900	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
BHG40_08905	COG0126	phosphoglycerate kinase activity
BHG40_08910	COG0191	fructose-bisphosphate aldolase activity
BHG40_08915	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BHG40_08965	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
BHG40_08970	COG1595	DNA-templated transcription, initiation
BHG40_08975	COG3073	An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E
BHG40_08990	COG0481	GTPase activity
BHG40_08995	COG0681	Belongs to the peptidase S26 family
BHG40_09000	COG0571	ribonuclease III activity
BHG40_09010	COG1381	Involved in DNA repair and RecF pathway recombination
BHG40_09015	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
BHG40_09020	COG3023	N-Acetylmuramoyl-L-alanine amidase
BHG40_09025	COG4807	Protein conserved in bacteria
BHG40_09035	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
BHG40_09040	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
BHG40_09045	COG3956	TIGRFAM MazG family protein
BHG40_09050	COG0504	CTP synthase activity
BHG40_09055	COG0148	phosphopyruvate hydratase activity
BHG40_09060	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
BHG40_09065	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
BHG40_09075	COG0585	pseudouridine synthase activity
BHG40_09080	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
BHG40_09085	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
BHG40_09090	COG1238	metal cluster binding
BHG40_09095	COG4942	peptidase
BHG40_09095	COG1388	LysM domain
BHG40_09105	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
BHG40_09110	COG1610	YqeY-like protein
BHG40_09115	COG0358	DNA primase activity
BHG40_09120	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
BHG40_09160	COG0151	Belongs to the GarS family
BHG40_09165	COG0138	bifunctional purine biosynthesis protein purh
BHG40_09175	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
BHG40_09180	COG3036	rescue of stalled ribosome
BHG40_09185	COG0635	Involved in the biosynthesis of porphyrin-containing compound
BHG40_09190	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
BHG40_09200	COG0673	inositol 2-dehydrogenase activity
BHG40_09210	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BHG40_09215	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BHG40_09220	COG3227	Zinc metalloprotease (Elastase)
BHG40_09230	COG0477	Major facilitator Superfamily
BHG40_09240	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
BHG40_09245	COG1027	Aspartate ammonia-lyase
BHG40_09250	COG3030	protein affecting phage T7 exclusion by the F plasmid
BHG40_09260	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
BHG40_09265	COG0459	protein refolding
BHG40_09275	COG5001	Diguanylate cyclase
BHG40_09275	COG3300	MHYT domain
BHG40_09285	COG0564	pseudouridine synthase activity
BHG40_09320	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BHG40_09330	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
BHG40_09335	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
BHG40_09340	COG1178	ABC-type Fe3 transport system permease component
BHG40_09345	COG4143	(ABC) transporter
BHG40_09360	COG0066	3-isopropylmalate dehydratase activity
BHG40_09365	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
BHG40_09370	COG0473	3-isopropylmalate dehydrogenase activity
BHG40_09375	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
BHG40_09385	COG0671	phosphoesterase, PA-phosphatase related
BHG40_09395	COG0028	Belongs to the TPP enzyme family
BHG40_09400	COG0440	acetolactate synthase activity
BHG40_09405	COG0280	phosphate acetyltransferase
BHG40_09405	COG0857	belongs to the CobB CobQ family
BHG40_09410	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
BHG40_09415	COG3092	negative regulation of chromosome organization
BHG40_09420	COG3013	Belongs to the UPF0304 family
BHG40_09425	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
BHG40_09430	COG2716	regulation of RNA biosynthetic process
BHG40_09440	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
BHG40_09445	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
BHG40_09480	COG2198	Histidine kinase
BHG40_09480	COG5002	protein histidine kinase activity
BHG40_09480	COG0784	Response regulator, receiver
BHG40_09505	COG0840	transmembrane signaling receptor activity
BHG40_09515	COG1464	Belongs to the NlpA lipoprotein family
BHG40_09520	COG2011	ABC-type metal ion transport system permease component
BHG40_09525	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
BHG40_09545	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
BHG40_09545	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
BHG40_09550	COG0802	atpase or kinase
BHG40_09560	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
BHG40_09565	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
BHG40_09570	COG1923	regulation of RNA biosynthetic process
BHG40_09575	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
BHG40_09580	COG0330	HflC and HflK could
BHG40_09585	COG0330	HflC and HflK could
BHG40_09590	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
BHG40_09595	COG0142	geranyltranstransferase activity
BHG40_09605	COG0211	Belongs to the bacterial ribosomal protein bL27 family
BHG40_09610	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
BHG40_09620	COG0318	PFAM AMP-dependent synthetase and ligase
BHG40_09640	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BHG40_09655	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
BHG40_09665	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
BHG40_09670	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
BHG40_09680	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
BHG40_09685	COG3178	'Phosphotransferase
BHG40_09690	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
BHG40_09695	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
BHG40_09700	COG2252	PERMEase
BHG40_09710	COG0488	(ABC) transporter
BHG40_09735	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BHG40_09745	COG3721	Heme iron utilization protein
BHG40_09750	COG0748	coenzyme F420 binding
BHG40_09795	COG3397	chitin binding
BHG40_09805	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BHG40_09810	COG1765	OsmC-like protein
BHG40_09825	COG3954	Phosphoribulokinase
BHG40_09835	COG2076	Multidrug Resistance protein
BHG40_09840	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
BHG40_09845	COG0726	polysaccharide deacetylase
BHG40_09855	COG0463	Glycosyl transferase, family 2
BHG40_09870	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
BHG40_09880	COG3089	Belongs to the UPF0270 family
BHG40_09885	COG5001	Diguanylate cyclase
BHG40_09885	COG2203	Gaf domain
BHG40_09885	COG4251	negative regulation of phosphorylation
BHG40_09885	COG3706	GGDEF domain
BHG40_09890	COG0429	hydrolase of the alpha beta-hydrolase fold
BHG40_09895	COG0784	Response regulator, receiver
BHG40_09895	COG0835	chemotaxis
BHG40_09905	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
BHG40_09910	COG1047	Peptidyl-prolyl cis-trans
BHG40_09915	COG2900	Belongs to the SlyX family
BHG40_09925	COG0545	Peptidyl-prolyl cis-trans isomerase
BHG40_09930	COG2204	response regulator
BHG40_09950	COG0737	Belongs to the 5'-nucleotidase family
BHG40_09955	COG2200	EAL domain
BHG40_09965	COG0305	Participates in initiation and elongation during chromosome replication
BHG40_09970	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
BHG40_09975	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
BHG40_09985	COG2203	Gaf domain
BHG40_09985	COG2199	diguanylate cyclase activity
BHG40_09985	COG2200	EAL domain
BHG40_10030	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
BHG40_10035	COG2201	protein-glutamate methylesterase activity
BHG40_10060	COG2916	Histone family protein nucleoid-structuring protein H-NS
BHG40_10065	COG3328	transposase activity
BHG40_10070	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
BHG40_10075	COG2375	cellular response to nickel ion
BHG40_10080	COG1538	Outer membrane efflux protein
BHG40_10085	COG1136	(ABC) transporter
BHG40_10085	COG0577	efflux transmembrane transporter activity
BHG40_10090	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BHG40_10100	COG1227	inorganic diphosphatase activity
BHG40_10105	COG0497	DNA recombination
BHG40_10110	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
BHG40_10115	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
BHG40_10120	COG0443	Heat shock 70 kDa protein
BHG40_10125	COG0484	heat shock protein binding
BHG40_10155	COG1285	pathogenesis
BHG40_10170	COG0640	Transcriptional regulator
BHG40_10205	COG0095	Lipoate-protein ligase
BHG40_10245	COG0708	Exodeoxyribonuclease III
BHG40_10300	COG2814	Major facilitator Superfamily
BHG40_10305	COG0109	protoheme IX farnesyltransferase activity
BHG40_10310	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
BHG40_10315	COG1845	cytochrome c oxidase, subunit III
BHG40_10320	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
BHG40_10325	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
BHG40_10360	COG1609	Transcriptional regulator
BHG40_10365	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BHG40_10365	COG1263	PTS System
BHG40_10385	COG5433	transposase activity
BHG40_10400	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BHG40_10410	COG2207	Transcriptional regulator
BHG40_10415	COG0538	isocitrate dehydrogenase activity
BHG40_10450	COG0582	viral genome integration into host DNA
BHG40_10460	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
BHG40_10465	COG2867	negative regulation of translational initiation
BHG40_10475	COG0702	epimerase
BHG40_10480	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BHG40_10510	COG4964	Belongs to the GSP D family
BHG40_10520	COG2894	cell division
BHG40_10560	COG1454	alcohol dehydrogenase
BHG40_10575	COG1957	nucleoside hydrolase
BHG40_10595	COG0840	transmembrane signaling receptor activity
BHG40_10600	COG1280	lysine exporter protein (LysE YggA)
BHG40_10610	COG5433	transposase activity
BHG40_10630	COG3263	regulation of cellular component size
BHG40_10635	COG1876	peptidase activity
BHG40_10640	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BHG40_10645	COG1393	Belongs to the ArsC family
BHG40_10650	COG0583	DNA-binding transcription factor activity
BHG40_10670	COG0017	Asparaginyl-tRNA synthetase
BHG40_10690	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
BHG40_10695	COG0156	8-amino-7-oxononanoate synthase activity
BHG40_10700	COG1073	alpha beta
BHG40_10700	COG2226	methyltransferase
BHG40_10705	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
BHG40_10710	COG0501	Belongs to the peptidase M48B family
BHG40_10720	COG3217	Mosc domain protein beta barrel domain protein
BHG40_10720	COG0633	Ferredoxin
BHG40_10720	COG0633	Ferredoxin
BHG40_10720	COG3217	Mosc domain protein beta barrel domain protein
BHG40_10735	COG1013	pyruvate-flavodoxin oxidoreductase activity
BHG40_10735	COG0674	pyruvate-flavodoxin oxidoreductase activity
BHG40_10735	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
BHG40_10735	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
BHG40_10750	COG0534	Mate efflux family protein
BHG40_10790	COG1309	transcriptional regulator
BHG40_10805	COG0791	NLP P60 protein
BHG40_10815	COG0583	DNA-binding transcription factor activity
BHG40_10825	COG2198	Histidine kinase
BHG40_10825	COG0643	Histidine kinase
BHG40_10830	COG2201	protein-glutamate methylesterase activity
BHG40_10835	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
BHG40_10840	COG1360	Flagellar Motor Protein
BHG40_10845	COG1192	Involved in chromosome partitioning
BHG40_10855	COG0835	chemotaxis
BHG40_10870	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
BHG40_10875	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
BHG40_10880	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
BHG40_10885	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
BHG40_10890	COG1138	Cytochrome C-type biogenesis protein
BHG40_10895	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BHG40_10900	COG4235	cytochrome complex assembly
BHG40_10900	COG3088	subunit of a heme lyase
BHG40_10920	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
BHG40_10925	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
BHG40_10925	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
BHG40_10940	COG0259	pyridoxamine-phosphate oxidase activity
BHG40_10975	COG2850	peptidyl-arginine hydroxylation
BHG40_10980	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
BHG40_10985	COG2915	High frequency lysogenization protein hflD homolog
BHG40_10990	COG0482	sulfurtransferase activity
BHG40_11010	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BHG40_11020	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BHG40_11020	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BHG40_11020	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BHG40_11035	COG5433	transposase activity
BHG40_11045	COG5433	transposase activity
BHG40_11070	COG0159	tryptophan synthase activity
BHG40_11075	COG0133	tryptophan synthase activity
BHG40_11080	COG0135	phosphoribosylanthranilate isomerase activity
BHG40_11080	COG0134	indole-3-glycerol-phosphate synthase activity
BHG40_11085	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
BHG40_11090	COG0512	Glutamine amidotransferase of anthranilate synthase
BHG40_11090	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
BHG40_11095	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
BHG40_11100	COG0613	PHP domain protein
BHG40_11105	COG0009	L-threonylcarbamoyladenylate synthase
BHG40_11115	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
BHG40_11125	COG1946	Acyl-CoA thioesterase
BHG40_11140	COG1309	transcriptional regulator
BHG40_11145	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BHG40_11155	COG1538	Outer membrane efflux protein
BHG40_11165	COG1091	dTDP-4-dehydrorhamnose reductase activity
BHG40_11180	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
BHG40_11185	COG1459	type II secretion system
BHG40_11220	COG0438	transferase activity, transferring glycosyl groups
BHG40_11240	COG5433	transposase activity
BHG40_11245	COG5433	transposase activity
BHG40_11255	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
BHG40_11270	COG5433	transposase activity
BHG40_11285	COG3132	Protein of unknown function, DUF480
BHG40_11340	COG1278	Cold shock
BHG40_11380	COG0697	spore germination
BHG40_11395	COG1187	pseudouridine synthase activity
BHG40_11405	COG4166	transmembrane transport
BHG40_11410	COG0622	Phosphoesterase
BHG40_11430	COG0835	chemotaxis
BHG40_11430	COG0784	Response regulator, receiver
BHG40_11435	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
BHG40_11440	COG1815	bacterial-type flagellum-dependent cell motility
BHG40_11445	COG1558	bacterial-type flagellum-dependent cell motility
BHG40_11460	COG4787	bacterial-type flagellum-dependent cell motility
BHG40_11465	COG4786	Flagellar basal body rod
BHG40_11470	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
BHG40_11500	COG2239	Acts as a magnesium transporter
BHG40_11505	COG0248	Ppx GppA phosphatase
BHG40_11510	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
BHG40_11530	COG3852	Histidine kinase
BHG40_11535	COG2204	response regulator
BHG40_11540	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
BHG40_11545	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
BHG40_11550	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
BHG40_11555	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
BHG40_11575	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
BHG40_11585	COG0590	tRNA wobble adenosine to inosine editing
BHG40_11590	COG0573	inorganic phosphate transmembrane transporter activity
BHG40_11595	COG0581	inorganic phosphate transmembrane transporter activity
BHG40_11605	COG0704	Plays a role in the regulation of phosphate uptake
BHG40_11610	COG1253	flavin adenine dinucleotide binding
BHG40_11625	COG0531	amino acid
BHG40_11635	COG1126	abc transporter atp-binding protein
BHG40_11640	COG0765	amino acid transport
BHG40_11645	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BHG40_11650	COG3706	GGDEF domain
BHG40_11655	COG2271	Major facilitator Superfamily
BHG40_11670	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
BHG40_11710	COG1199	ATP-dependent helicase activity
BHG40_11715	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
BHG40_11725	COG1448	Aminotransferase
BHG40_11730	COG0433	COG0433 Predicted ATPase
BHG40_11745	COG0658	competence protein
BHG40_11745	COG2333	competence protein COMEC
BHG40_11750	COG1132	(ABC) transporter
BHG40_11755	COG1663	tetraacyldisaccharide 4'-kinase activity
BHG40_11760	COG2835	tetraacyldisaccharide 4'-kinase activity
BHG40_11765	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
BHG40_11770	COG2197	response regulator
BHG40_11775	COG0322	excinuclease ABC activity
BHG40_11810	COG2261	transglycosylase associated protein
BHG40_11815	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
BHG40_11825	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
BHG40_11855	COG2203	Gaf domain
BHG40_11855	COG2199	diguanylate cyclase activity
BHG40_11885	COG2119	membrane
BHG40_11890	COG0023	Translation Initiation Factor
BHG40_11930	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BHG40_11930	COG2205	protein histidine kinase activity
BHG40_11940	COG4138	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system
BHG40_11945	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
BHG40_11950	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
BHG40_11955	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
BHG40_11960	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
BHG40_11965	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
BHG40_11980	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
BHG40_11985	COG0505	Belongs to the CarA family
BHG40_11990	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
BHG40_11995	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
BHG40_12025	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BHG40_12030	COG0513	Belongs to the DEAD box helicase family
BHG40_12070	COG5433	transposase activity
BHG40_12075	COG0070	glutamate synthase
BHG40_12075	COG0069	glutamate synthase activity
BHG40_12075	COG0067	glutamate synthase
BHG40_12080	COG0493	'glutamate synthase
BHG40_12095	COG0789	Transcriptional regulator
BHG40_12130	COG1252	NADH dehydrogenase
BHG40_12135	COG0393	Putative heavy-metal-binding
BHG40_12145	COG1619	proteins homologs of microcin C7 resistance protein MccF
BHG40_12150	COG1368	sulfuric ester hydrolase activity
BHG40_12160	COG0527	aspartate kinase activity
BHG40_12165	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
BHG40_12165	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
BHG40_12170	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BHG40_12215	COG1285	pathogenesis
BHG40_12235	COG1136	(ABC) transporter
BHG40_12250	COG2814	Major facilitator Superfamily
BHG40_12275	COG0672	)-iron permease
BHG40_12340	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
BHG40_12345	COG0574	Belongs to the PEP-utilizing enzyme family
BHG40_12345	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
BHG40_12380	COG5433	transposase activity
BHG40_12395	COG5433	transposase activity
BHG40_12405	COG0671	phosphoesterase, PA-phosphatase related
BHG40_12415	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
BHG40_12425	COG0101	tRNA pseudouridine synthase activity
BHG40_12430	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
BHG40_12435	COG0285	dihydrofolate synthase activity
BHG40_12440	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
BHG40_12445	COG2920	part of a sulfur-relay system
BHG40_12450	COG1289	transmembrane transporter activity
BHG40_12455	COG0670	Belongs to the BI1 family
BHG40_12465	COG0840	transmembrane signaling receptor activity
BHG40_12485	COG0564	pseudouridine synthase activity
BHG40_12510	COG0625	glutathione transferase activity
BHG40_12515	COG0625	glutathione transferase activity
BHG40_12540	COG0367	asparagine synthase
BHG40_12550	COG4651	solute:proton antiporter activity
BHG40_12550	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
BHG40_12555	COG0647	UMP catabolic process
BHG40_12565	COG1902	pentaerythritol trinitrate reductase activity
BHG40_12570	COG1253	flavin adenine dinucleotide binding
BHG40_12580	COG0247	lactate metabolic process
BHG40_12580	COG0277	FAD linked oxidase domain protein
BHG40_12590	COG2050	protein possibly involved in aromatic compounds catabolism
BHG40_12595	COG0513	Belongs to the DEAD box helicase family
BHG40_12605	COG3300	MHYT domain
BHG40_12605	COG5001	Diguanylate cyclase
BHG40_12610	COG2056	Na+-H+ antiporter family
BHG40_12615	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
BHG40_12630	COG0346	lactoylglutathione lyase activity
BHG40_12635	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
BHG40_12645	COG4659	FMN binding
BHG40_12650	COG4658	electron transport chain
BHG40_12660	COG2878	Part of a membrane complex involved in electron transport
BHG40_12665	COG4657	Part of a membrane complex involved in electron transport
BHG40_12670	COG0697	spore germination
BHG40_12715	COG0659	secondary active sulfate transmembrane transporter activity
BHG40_12815	COG3501	Rhs element vgr protein
BHG40_12845	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
BHG40_12850	COG1278	Cold shock
BHG40_12855	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
BHG40_12860	COG0542	response to heat
BHG40_12865	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
BHG40_12870	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
BHG40_12875	COG3134	Outer membrane lipoprotein
BHG40_12885	COG0492	ferredoxin-NADP+ reductase activity
BHG40_12895	COG0686	Belongs to the AlaDH PNT family
BHG40_12905	COG1674	ftsk spoiiie
BHG40_12905	COG0531	amino acid
BHG40_12910	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
BHG40_12915	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
BHG40_12920	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
BHG40_12925	COG1286	toxin biosynthetic process
BHG40_12930	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
BHG40_12940	COG4172	Belongs to the ABC transporter superfamily
BHG40_12945	COG4172	Belongs to the ABC transporter superfamily
BHG40_12950	COG4171	peptide transport system, permease
BHG40_12955	COG4168	peptide transport system, permease
BHG40_12965	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
BHG40_12970	COG1842	Phage shock protein A
BHG40_12985	COG3106	COG3106 Predicted ATPase
BHG40_12990	COG3768	UPF0283 membrane protein
BHG40_13000	COG2154	pterin-4-alpha-carbinolamine dehydratase
BHG40_13015	COG2199	diguanylate cyclase activity
BHG40_13025	COG0861	Integral membrane protein TerC family
BHG40_13040	COG1022	Amp-dependent synthetase and ligase
BHG40_13045	COG0295	cytidine deaminase activity
BHG40_13050	COG1346	cytolysis
BHG40_13055	COG1380	Effector of murein hydrolase LrgA
BHG40_13065	COG3345	alpha-galactosidase
BHG40_13075	COG2925	Exonuclease
BHG40_13090	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BHG40_13095	COG0436	Aminotransferase
BHG40_13100	COG0583	DNA-binding transcription factor activity
BHG40_13105	COG2160	L-arabinose isomerase activity
BHG40_13115	COG1069	ribulokinase activity
BHG40_13120	COG1879	ABC-type sugar transport system periplasmic component
BHG40_13130	COG1172	Belongs to the binding-protein-dependent transport system permease family
BHG40_13140	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
BHG40_13145	COG1085	galactose-1-phosphate uridylyltransferase
BHG40_13160	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
BHG40_13165	COG1609	Transcriptional regulator
BHG40_13175	COG4580	involved in the transport of maltose and maltodextrins
BHG40_13215	COG2182	Extracellular solute-binding protein
BHG40_13240	COG3833	ABC-type maltose transport systems, permease component
BHG40_13245	COG3867	Arabinogalactan endo-beta-1,4-galactanase
BHG40_13250	COG1874	Beta-galactosidase
BHG40_13260	COG0257	Belongs to the bacterial ribosomal protein bL36 family
BHG40_13265	COG0254	rRNA binding
BHG40_13280	COG1451	nucleotide metabolic process
BHG40_13295	COG3069	C4-dicarboxylate transmembrane transporter activity
BHG40_13310	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
BHG40_13330	COG2009	succinate dehydrogenase
BHG40_13335	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
BHG40_13340	COG1053	succinate dehydrogenase
BHG40_13350	COG0567	Dehydrogenase, E1 component
BHG40_13355	COG0508	dehydrogenase complex catalyzes the overall conversion of
BHG40_13360	COG0045	succinate-CoA ligase (ADP-forming) activity
BHG40_13365	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
BHG40_13375	COG1882	Formate acetyltransferase
BHG40_13380	COG2116	formate transmembrane transporter activity
BHG40_13385	COG1944	ATP diphosphatase activity
BHG40_13390	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
BHG40_13410	COG2910	NAD(P)H-binding
BHG40_13415	COG0583	DNA-binding transcription factor activity
BHG40_13425	COG3708	Transcriptional regulator
BHG40_13425	COG2207	Transcriptional regulator
BHG40_13430	COG4774	siderophore transport
BHG40_13440	COG0583	DNA-binding transcription factor activity
BHG40_13445	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
BHG40_13475	COG3046	protein related to deoxyribodipyrimidine photolyase
BHG40_13480	COG3033	Beta-eliminating lyase
BHG40_13495	COG3088	subunit of a heme lyase
BHG40_13495	COG4235	cytochrome complex assembly
BHG40_13510	COG3301	Polysulphide reductase, NrfD
BHG40_13515	COG0437	4 iron, 4 sulfur cluster binding
BHG40_13520	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
BHG40_13530	COG0247	lactate metabolic process
BHG40_13535	COG3075	Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses fumarate or nitrate as electron acceptor
BHG40_13540	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
BHG40_13545	COG3012	SEC-C Motif Domain Protein
BHG40_13550	COG0840	transmembrane signaling receptor activity
BHG40_13555	COG1940	carbohydrate kinase activity
BHG40_13555	COG1846	Transcriptional regulator
BHG40_13560	COG3290	protein histidine kinase activity
BHG40_13565	COG4565	transcriptional regulatory protein
BHG40_13595	COG5433	transposase activity
BHG40_13605	COG0569	domain protein
BHG40_13605	COG2985	domain, Protein
BHG40_13615	COG0556	nucleotide-excision repair
BHG40_13625	COG0586	Pfam SNARE associated Golgi protein
BHG40_13630	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
BHG40_13635	COG3067	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
BHG40_13640	COG2186	Transcriptional regulator
BHG40_13655	COG2766	serine protein kinase
BHG40_13660	COG0514	ATP-dependent DNA helicase (RecQ)
BHG40_13665	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
BHG40_13670	COG0814	amino acid
BHG40_13680	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
BHG40_13705	COG5433	transposase activity
BHG40_13750	COG0058	SHG alpha-glucan phosphorylase activity
BHG40_13755	COG0471	metal ion transport
BHG40_13760	COG3118	belongs to the thioredoxin family
BHG40_13775	COG1132	(ABC) transporter
BHG40_13785	COG2501	S4 domain
BHG40_13795	COG3243	poly(R)-hydroxyalkanoic acid synthase
BHG40_13815	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
BHG40_13820	COG2329	Antibiotic biosynthesis monooxygenase
BHG40_13855	COG1742	UPF0060 membrane protein
BHG40_13870	COG0513	Belongs to the DEAD box helicase family
BHG40_13875	COG0386	Belongs to the glutathione peroxidase family
BHG40_13885	COG1181	Belongs to the D-alanine--D-alanine ligase family
BHG40_13900	COG0730	response to heat
BHG40_13905	COG0583	DNA-binding transcription factor activity
BHG40_13920	COG3593	DNA synthesis involved in DNA repair
BHG40_13975	COG1011	Hydrolase
BHG40_14015	COG1434	Gram-negative-bacterium-type cell wall biogenesis
BHG40_14025	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
BHG40_14035	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
BHG40_14040	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
BHG40_14045	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
BHG40_14070	COG0242	peptide deformylase activity
BHG40_14110	COG4681	YaeQ
BHG40_14130	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BHG40_14150	COG3134	Outer membrane lipoprotein
BHG40_14180	COG0583	DNA-binding transcription factor activity
BHG40_14185	COG2723	6-phospho-beta-galactosidase activity
BHG40_14195	COG0583	DNA-binding transcription factor activity
BHG40_14200	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
BHG40_14205	COG0673	inositol 2-dehydrogenase activity
BHG40_14210	COG0583	DNA-binding transcription factor activity
BHG40_14220	COG1560	Kdo2-lipid A biosynthetic process
BHG40_14250	COG0417	DNA replication proofreading
BHG40_14285	COG0534	Mate efflux family protein
BHG40_14295	COG0307	riboflavin synthase, alpha
BHG40_14305	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BHG40_14310	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
BHG40_14315	COG0697	spore germination
BHG40_14320	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
BHG40_14360	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BHG40_14370	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
BHG40_14375	COG2894	cell division
BHG40_14380	COG0850	regulation of cytokinetic process
BHG40_14385	COG3100	YcgL domain-containing protein
BHG40_14390	COG2951	lytic endotransglycosylase activity
BHG40_14395	COG1760	l-serine dehydratase
BHG40_14400	COG1760	l-serine dehydratase
BHG40_14405	COG3123	guanosine phosphorylase activity
BHG40_14425	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
BHG40_14430	COG2067	long-chain fatty acid transport protein
BHG40_14435	COG2067	long-chain fatty acid transport protein
BHG40_14475	COG0714	Associated with various cellular activities
BHG40_14480	COG0183	Belongs to the thiolase family
BHG40_14485	COG1024	Enoyl-CoA hydratase
BHG40_14485	COG1250	3-hydroxyacyl-CoA dehydrogenase
BHG40_14490	COG2824	Alkylphosphonate utilization operon protein PhnA
BHG40_14535	COG3706	GGDEF domain
BHG40_14540	COG2840	Smr protein MutS2
BHG40_14545	COG2890	protein-(glutamine-N5) methyltransferase activity
BHG40_14550	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
BHG40_14560	COG0513	Belongs to the DEAD box helicase family
BHG40_14565	COG5654	RES domain protein
BHG40_14575	COG0814	amino acid
BHG40_14580	COG1609	Transcriptional regulator
BHG40_14585	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
BHG40_14585	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
BHG40_14590	COG1105	Belongs to the carbohydrate kinase PfkB family
BHG40_14595	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
BHG40_14595	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BHG40_14595	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BHG40_14600	COG3313	Fe-S protein
BHG40_14605	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
BHG40_14610	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
BHG40_14615	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BHG40_14620	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BHG40_14630	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
BHG40_14650	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
BHG40_14655	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
BHG40_14660	COG0291	Belongs to the bacterial ribosomal protein bL35 family
BHG40_14665	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
BHG40_14670	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
BHG40_14675	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BHG40_14675	COG0072	phenylalanine-tRNA ligase activity
BHG40_14680	COG0776	regulation of translation
BHG40_14685	COG2205	protein histidine kinase activity
BHG40_14685	COG0784	Response regulator, receiver
BHG40_14700	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
BHG40_14720	COG1609	Transcriptional regulator
BHG40_14725	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BHG40_14730	COG1879	ABC-type sugar transport system periplasmic component
BHG40_14735	COG1172	Belongs to the binding-protein-dependent transport system permease family
BHG40_14745	COG1869	D-ribose catabolic process
BHG40_14765	COG0037	tRNA processing
BHG40_14770	COG0589	response to stress
BHG40_14775	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BHG40_14790	COG2217	Heavy metal translocating P-type atpase
BHG40_14800	COG2010	Cytochrome c
BHG40_14815	COG3278	Belongs to the heme-copper respiratory oxidase family
BHG40_14825	COG1956	GAF domain-containing protein
BHG40_14830	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
BHG40_14840	COG0308	aminopeptidase N
BHG40_14860	COG0167	dihydroorotate dehydrogenase activity
BHG40_14875	COG0116	Belongs to the methyltransferase superfamily
BHG40_14875	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
BHG40_14895	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
BHG40_14900	COG1067	ATP-dependent peptidase activity
BHG40_15125	COG5433	transposase activity
BHG40_15180	COG3620	sequence-specific DNA binding
BHG40_15210	COG4221	oxidoreductase activity
BHG40_15255	COG0372	Belongs to the citrate synthase family
BHG40_15260	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
BHG40_15270	COG2995	paraquat-inducible protein a
BHG40_15280	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
BHG40_15280	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
BHG40_15295	COG0084	hydrolase, TatD family'
BHG40_15300	COG0470	DNA polymerase III
BHG40_15305	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
BHG40_15310	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
BHG40_15315	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BHG40_15320	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
BHG40_15325	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BHG40_15330	COG1028	Short-chain dehydrogenase reductase Sdr
BHG40_15340	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BHG40_15345	COG0416	fatty acid biosynthetic process
BHG40_15350	COG0333	Belongs to the bacterial ribosomal protein bL32 family
BHG40_15355	COG1399	metal-binding, possibly nucleic acid-binding protein
BHG40_15360	COG0424	maF-like protein
BHG40_15365	COG0546	phosphoglycolate phosphatase activity
BHG40_15375	COG1530	ribonuclease E activity
BHG40_15380	COG0306	phosphate transporter
BHG40_15385	COG0717	Belongs to the dCTP deaminase family
BHG40_15390	COG0572	uridine kinase
BHG40_15395	COG0489	protein tyrosine kinase activity
BHG40_15400	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BHG40_15400	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BHG40_15405	COG0625	glutathione transferase activity
BHG40_15410	COG1254	Belongs to the acylphosphatase family
BHG40_15420	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
BHG40_15435	COG0709	Synthesizes selenophosphate from selenide and ATP
BHG40_15440	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
BHG40_15445	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BHG40_15450	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
BHG40_15460	COG1643	Atp-dependent helicase
BHG40_15470	COG2197	response regulator
BHG40_15480	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
BHG40_15485	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
BHG40_15490	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
BHG40_15495	COG2832	Protein of unknown function (DUF454)
BHG40_15500	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
BHG40_15520	COG0318	PFAM AMP-dependent synthetase and ligase
BHG40_15525	COG2267	carboxylic ester hydrolase activity
BHG40_15535	COG1214	PFAM Peptidase M22, glycoprotease
BHG40_15540	COG1199	ATP-dependent helicase activity
BHG40_15550	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
BHG40_15555	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
BHG40_15560	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
BHG40_15565	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
BHG40_15565	COG0131	Imidazoleglycerol-phosphate dehydratase
BHG40_15570	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
BHG40_15575	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
BHG40_15580	COG3437	response regulator, receiver
BHG40_15590	COG2205	protein histidine kinase activity
BHG40_15590	COG0784	Response regulator, receiver
BHG40_15590	COG2198	Histidine kinase
BHG40_15595	COG0107	imidazoleglycerol-phosphate synthase activity
BHG40_15600	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
BHG40_15600	COG0140	phosphoribosyl-ATP diphosphatase activity
BHG40_15610	COG2378	regulation of single-species biofilm formation
BHG40_15640	COG0730	response to heat
BHG40_15650	COG1028	Short-chain dehydrogenase reductase Sdr
BHG40_15660	COG1024	Enoyl-CoA hydratase
BHG40_15665	COG1024	Enoyl-CoA hydratase
BHG40_15670	COG1960	acyl-CoA dehydrogenase activity
BHG40_15695	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
BHG40_15700	COG1024	Enoyl-CoA hydratase
BHG40_15730	COG1584	GPR1 FUN34 yaaH family protein
BHG40_15740	COG0456	acetyltransferase
BHG40_15750	COG1024	Enoyl-CoA hydratase
BHG40_15750	COG1250	3-hydroxyacyl-CoA dehydrogenase
BHG40_15765	COG3162	membrane
BHG40_15770	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BHG40_15775	COG0488	(ABC) transporter
BHG40_15780	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BHG40_15785	COG0776	regulation of translation
BHG40_15790	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
BHG40_15795	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
BHG40_15800	COG0740	serine-type endopeptidase activity
BHG40_15805	COG0544	peptidyl-prolyl cis-trans isomerase activity
BHG40_15815	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
BHG40_15820	COG4591	ABC-type transport system involved in lipoprotein release permease component
BHG40_15825	COG1136	(ABC) transporter
BHG40_15830	COG4591	ABC-type transport system involved in lipoprotein release permease component
BHG40_15840	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
BHG40_15845	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
BHG40_15850	COG4166	transmembrane transport
BHG40_15855	COG0697	spore germination
BHG40_15865	COG2062	phosphohistidine phosphatase, SixA
BHG40_15920	COG0519	Catalyzes the synthesis of GMP from XMP
BHG40_15920	COG0518	GMP synthase (glutamine-hydrolyzing) activity
BHG40_15925	COG0516	GMP reductase activity
BHG40_15925	COG0517	IMP dehydrogenase activity
BHG40_15950	COG5433	transposase activity
BHG40_15970	COG1570	exodeoxyribonuclease VII activity
BHG40_15985	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
BHG40_15990	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
BHG40_15995	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
BHG40_16015	COG0598	Magnesium transport protein CorA
BHG40_16035	COG4771	TonB-dependent receptor
BHG40_16040	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BHG40_16045	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BHG40_16050	COG1120	ATPase activity
BHG40_16055	COG2977	Belongs to the P-Pant transferase superfamily
BHG40_16060	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BHG40_16065	COG1028	Short-chain dehydrogenase reductase Sdr
BHG40_16065	COG3321	synthase
BHG40_16065	COG0318	PFAM AMP-dependent synthetase and ligase
BHG40_16065	COG0300	oxidoreductase activity
BHG40_16065	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BHG40_16075	COG1028	Short-chain dehydrogenase reductase Sdr
BHG40_16080	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BHG40_16085	COG3433	isochorismatase activity
BHG40_16085	COG1535	isochorismatase
BHG40_16090	COG1021	2,3-dihydroxybenzoate-AMP ligase
BHG40_16145	COG0840	transmembrane signaling receptor activity
BHG40_16150	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BHG40_16155	COG3788	relative of glutathione S-transferase, MAPEG superfamily
BHG40_16160	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
BHG40_16165	COG0563	adenylate kinase activity
BHG40_16175	COG0326	Molecular chaperone. Has ATPase activity
BHG40_16180	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
BHG40_16200	COG3383	formate dehydrogenase (NAD+) activity
BHG40_16205	COG3383	formate dehydrogenase (NAD+) activity
BHG40_16225	COG3158	transport of potassium into the cell
BHG40_16230	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
BHG40_16235	COG0651	ATP synthesis coupled electron transport
BHG40_16240	COG0650	Formate hydrogenlyase subunit 4
BHG40_16245	COG3261	NADH dehydrogenase
BHG40_16245	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
BHG40_16250	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BHG40_16255	COG3260	NADH ubiquinone oxidoreductase 20
BHG40_16265	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
BHG40_16270	COG1921	L-seryl-tRNASec selenium transferase activity
BHG40_16280	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
BHG40_16285	COG0298	carbon dioxide binding
BHG40_16295	COG0309	Hydrogenase expression formation protein (HypE)
BHG40_16300	COG0375	protein maturation
BHG40_16305	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
BHG40_16320	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BHG40_16325	COG0601	transmembrane transport
BHG40_16335	COG1773	rubredoxin
BHG40_16340	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
BHG40_16345	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
BHG40_16350	COG5557	Pfam Polysulphide reductase, NrfD
BHG40_16355	COG0437	4 iron, 4 sulfur cluster binding
BHG40_16365	COG5433	transposase activity
BHG40_16380	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
BHG40_16405	COG1435	thymidine kinase activity
BHG40_16410	COG1757	Na H antiporter
BHG40_16425	COG2916	Histone family protein nucleoid-structuring protein H-NS
BHG40_16430	COG2096	Adenosyltransferase
BHG40_16435	COG3530	Putative quorum-sensing-regulated virulence factor
BHG40_16440	COG0602	queuosine metabolic process
BHG40_16445	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
BHG40_16460	COG0284	orotidine-5'-phosphate decarboxylase activity
BHG40_16465	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
BHG40_16475	COG0776	regulation of translation
BHG40_16480	COG0539	negative regulation of cytoplasmic translation
BHG40_16485	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
BHG40_16490	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
BHG40_16505	COG2814	Major facilitator Superfamily
BHG40_16525	COG5001	Diguanylate cyclase
BHG40_16525	COG3300	MHYT domain
BHG40_16540	COG0583	DNA-binding transcription factor activity
BHG40_16545	COG3437	response regulator, receiver
BHG40_16570	COG4989	oxidoreductase activity
BHG40_16575	COG0724	RNA recognition motif
BHG40_16585	COG1126	abc transporter atp-binding protein
BHG40_16590	COG0765	amino acid transport
BHG40_16595	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BHG40_16600	COG4597	amino acid ABC transporter
BHG40_16615	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
BHG40_16635	COG1360	Flagellar Motor Protein
BHG40_16640	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BHG40_16650	COG0649	NAD binding
BHG40_16650	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BHG40_16665	COG1034	ATP synthesis coupled electron transport
BHG40_16670	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
BHG40_16675	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BHG40_16680	COG0839	Belongs to the complex I subunit 6 family
BHG40_16685	COG0713	ATP synthesis coupled electron transport
BHG40_16695	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BHG40_16700	COG1007	ATP synthesis coupled electron transport
BHG40_16715	COG5433	transposase activity
BHG40_16730	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BHG40_16735	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BHG40_16770	COG0537	adenosine 5'-monophosphoramidase activity
BHG40_16785	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
BHG40_16800	COG1301	dicarboxylic acid transport
BHG40_16810	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
BHG40_16815	COG0861	Integral membrane protein TerC family
BHG40_16830	COG0444	Belongs to the ABC transporter superfamily
BHG40_16835	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BHG40_16840	COG0601	transmembrane transport
BHG40_16850	COG2095	MarC family integral membrane protein
BHG40_16860	COG1454	alcohol dehydrogenase
BHG40_16860	COG1012	belongs to the aldehyde dehydrogenase family
BHG40_16880	COG3275	phosphorelay sensor kinase activity
BHG40_16885	COG3279	Response regulator of the LytR AlgR family
BHG40_16890	COG1966	Carbon starvation protein
BHG40_16900	COG1566	PFAM secretion protein HlyD family protein
BHG40_16905	COG1061	Type III restriction enzyme res subunit
BHG40_16910	COG2027	D-alanyl-D-alanine carboxypeptidase
BHG40_16915	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
BHG40_16925	COG0436	Aminotransferase
BHG40_16930	COG1288	antiporter activity
BHG40_16935	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
BHG40_17010	COG1242	4 iron, 4 sulfur cluster binding
BHG40_17015	COG5433	transposase activity
BHG40_17025	COG5433	transposase activity
BHG40_17035	COG5433	transposase activity
BHG40_17050	COG2354	Protein conserved in bacteria
BHG40_17060	COG0047	phosphoribosylformylglycinamidine synthase activity
BHG40_17060	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
BHG40_17065	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
BHG40_17070	COG1645	bacterial-type flagellum-dependent swarming motility
BHG40_17075	COG1160	GTP binding
BHG40_17080	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BHG40_17085	COG2976	Protein conserved in bacteria
BHG40_17090	COG0124	histidyl-tRNA synthetase
BHG40_17095	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
BHG40_17100	COG1426	Protein conserved in bacteria
BHG40_17110	COG0820	rRNA (adenine-C2-)-methyltransferase activity
BHG40_17115	COG0105	UTP biosynthetic process
BHG40_17120	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
BHG40_17130	COG0633	Ferredoxin
BHG40_17135	COG0443	Heat shock 70 kDa protein
BHG40_17140	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
BHG40_17150	COG0822	iron-sulfur transferase activity
BHG40_17155	COG1104	cysteine desulfurase activity
BHG40_17160	COG1959	2 iron, 2 sulfur cluster binding
BHG40_17195	COG2897	thiosulfate sulfurtransferase activity
BHG40_17200	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BHG40_17205	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BHG40_17210	COG1862	Preprotein translocase
BHG40_17215	COG0343	queuine tRNA-ribosyltransferase activity
BHG40_17220	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
BHG40_17225	COG0517	IMP dehydrogenase activity
BHG40_17230	COG0450	alkyl hydroperoxide reductase
BHG40_17235	COG3634	alkyl hydroperoxide reductase activity
BHG40_17250	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
BHG40_17250	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
BHG40_17255	COG0509	glycine decarboxylation via glycine cleavage system
BHG40_17260	COG0404	The glycine cleavage system catalyzes the degradation of glycine
BHG40_17265	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BHG40_17270	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BHG40_17290	COG0243	molybdopterin cofactor binding
BHG40_17295	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
BHG40_17305	COG2814	Major facilitator Superfamily
BHG40_17310	COG0444	Belongs to the ABC transporter superfamily
BHG40_17315	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BHG40_17320	COG0601	transmembrane transport
BHG40_17330	COG0625	glutathione transferase activity
BHG40_17340	COG0483	inositol monophosphate 1-phosphatase activity
BHG40_17360	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
BHG40_17370	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BHG40_17400	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
BHG40_17415	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BHG40_17415	COG0301	tRNA thio-modification
BHG40_17425	COG4953	penicillin-binding protein 1C
BHG40_17430	COG2373	Large extracellular alpha-helical protein
BHG40_17435	COG0446	pyridine nucleotide-disulphide oxidoreductase
BHG40_17445	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
BHG40_17465	COG4215	(ABC) transporter
BHG40_17480	COG2431	L-lysine efflux transmembrane transporter activity
BHG40_17495	COG1393	Belongs to the ArsC family
BHG40_17505	COG4783	chaperone-mediated protein folding
BHG40_17510	COG0425	Belongs to the sulfur carrier protein TusA family
BHG40_17515	COG0628	permease
BHG40_17530	COG3842	ATPase activity
BHG40_17545	COG2182	Extracellular solute-binding protein
BHG40_17550	COG3081	Nucleoid-associated protein
BHG40_17555	COG3082	Protein of unknown function (DUF1414)
BHG40_17560	COG3083	sulfuric ester hydrolase activity
BHG40_17580	COG1770	oligopeptidase
BHG40_17600	COG4574	serine-type endopeptidase inhibitor activity
BHG40_17605	COG3085	chromosome segregation
BHG40_17610	COG0583	DNA-binding transcription factor activity
BHG40_17615	COG1605	Chorismate mutase
BHG40_17615	COG0287	Prephenate dehydrogenase
BHG40_17620	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
BHG40_17625	COG0584	glycerophosphoryl diester phosphodiesterase
BHG40_17630	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
BHG40_17640	COG1349	DNA-binding transcription factor activity
BHG40_17645	COG2271	Major facilitator Superfamily
BHG40_17650	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
BHG40_17655	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
BHG40_17660	COG0583	DNA-binding transcription factor activity
BHG40_17685	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
BHG40_17690	COG0656	L-ascorbic acid biosynthetic process
BHG40_17695	COG2814	Major facilitator Superfamily
BHG40_17725	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BHG40_17730	COG2979	Protein of unknown function (DUF533)
BHG40_17750	COG0583	DNA-binding transcription factor activity
BHG40_17760	COG2807	transmembrane transport
BHG40_17765	COG1187	pseudouridine synthase activity
BHG40_17770	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
BHG40_17780	COG0346	lactoylglutathione lyase activity
BHG40_17795	COG1166	arginine decarboxylase activity
BHG40_17805	COG2195	Cleaves the N-terminal amino acid of tripeptides
BHG40_17830	COG2353	YceI-like domain
BHG40_17835	COG0583	DNA-binding transcription factor activity
BHG40_17845	COG2759	Belongs to the formate--tetrahydrofolate ligase family
BHG40_17850	COG0840	transmembrane signaling receptor activity
BHG40_17855	COG0302	gtp cyclohydrolase
BHG40_17865	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
BHG40_17895	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
BHG40_17910	COG0314	molybdopterin synthase activity
BHG40_17915	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
BHG40_17920	COG0315	cyclic pyranopterin monophosphate synthase activity
BHG40_17925	COG0521	Mo-molybdopterin cofactor biosynthetic process
BHG40_17930	COG3005	denitrification pathway
BHG40_17940	COG0348	domain, Protein
BHG40_17945	COG0437	4 iron, 4 sulfur cluster binding
BHG40_17950	COG0243	molybdopterin cofactor binding
BHG40_17960	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
BHG40_17965	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
BHG40_17970	COG3850	Histidine kinase
BHG40_17975	COG2197	response regulator
BHG40_18005	COG0121	glutamine amidotransferase
BHG40_18010	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
BHG40_18015	COG1960	acyl-CoA dehydrogenase activity
BHG40_18020	COG3437	response regulator, receiver
BHG40_18020	COG0784	Response regulator, receiver
BHG40_18030	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
BHG40_18035	COG0328	RNA-DNA hybrid ribonuclease activity
BHG40_18040	COG2226	methyltransferase
BHG40_18045	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BHG40_18050	COG0741	lytic transglycosylase activity
BHG40_18050	COG1388	LysM domain
BHG40_18055	COG3021	interspecies interaction between organisms
BHG40_18060	COG1607	acyl-coa hydrolase
BHG40_18085	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
BHG40_18100	COG2911	Protein conserved in bacteria
BHG40_18105	COG0729	surface antigen
BHG40_18120	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BHG40_18125	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BHG40_18135	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
BHG40_18145	COG4134	Bacterial extracellular solute-binding protein
BHG40_18150	COG4135	transport system, permease component
BHG40_18155	COG4136	ATPase activity
BHG40_18160	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
BHG40_18165	COG2951	lytic endotransglycosylase activity
BHG40_18170	COG1846	Transcriptional regulator
BHG40_18180	COG0033	Phosphoglucomutase
BHG40_18185	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
BHG40_18190	COG0596	Alpha beta hydrolase
BHG40_18205	COG0716	FMN binding
BHG40_18215	COG0735	belongs to the Fur family
BHG40_18220	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
BHG40_18240	COG0363	glucosamine-6-phosphate deaminase activity
BHG40_18245	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
BHG40_18250	COG1846	Transcriptional regulator
BHG40_18250	COG1940	carbohydrate kinase activity
BHG40_18265	COG2801	Transposase and inactivated derivatives
BHG40_18300	COG0217	transcriptional regulatory protein
BHG40_18305	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
BHG40_18325	COG4106	trans-aconitate 2-methyltransferase activity
BHG40_18330	COG0500	methyltransferase
BHG40_18350	COG0450	alkyl hydroperoxide reductase
BHG40_18360	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
BHG40_18375	COG0455	bacterial-type flagellum organization
BHG40_18385	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
BHG40_18395	COG1684	flagellar biosynthetic protein fliR
BHG40_18400	COG1987	bacterial-type flagellum assembly
BHG40_18450	COG1342	Belongs to the UPF0251 family
BHG40_18470	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
BHG40_18495	COG1737	Transcriptional regulator
BHG40_18500	COG0469	pyruvate kinase activity
BHG40_18510	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BHG40_18515	COG1960	acyl-CoA dehydrogenase activity
BHG40_18555	COG1388	LysM domain
BHG40_18555	COG1376	ErfK ybiS ycfS ynhG family protein
BHG40_18570	COG3129	Specifically methylates the adenine in position 1618 of 23S rRNA
BHG40_18575	COG0791	NLP P60 protein
BHG40_18580	COG2091	lysine biosynthetic process via aminoadipic acid
BHG40_18585	COG3118	belongs to the thioredoxin family
BHG40_18595	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
BHG40_18600	COG0788	formyltetrahydrofolate deformylase activity
BHG40_18630	COG0366	Alpha amylase catalytic
BHG40_18640	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
BHG40_18645	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
BHG40_18660	COG5433	transposase activity
BHG40_18675	COG1032	radical SAM domain protein
BHG40_18685	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BHG40_18690	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BHG40_18700	COG1752	Esterase of the alpha-beta hydrolase superfamily
BHG40_18705	COG0733	neurotransmitter:sodium symporter activity
BHG40_18735	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
BHG40_18735	COG2885	chlorophyll binding
BHG40_18740	COG0281	malic enzyme
BHG40_18745	COG2207	Transcriptional regulator
BHG40_18750	COG0534	Mate efflux family protein
BHG40_18760	COG3706	GGDEF domain
BHG40_18760	COG0745	RESPONSE REGULATOR receiver
BHG40_18765	COG2233	PERMEase
BHG40_18770	COG0095	Lipoate-protein ligase
BHG40_18775	COG1115	amino acid carrier protein
BHG40_18780	COG0019	diaminopimelate decarboxylase activity
BHG40_18800	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
BHG40_18820	COG1131	(ABC) transporter
BHG40_18825	COG0545	Peptidyl-prolyl cis-trans isomerase
BHG40_18830	COG3142	Participates in the control of copper homeostasis
BHG40_18835	COG1940	carbohydrate kinase activity
BHG40_18845	COG4783	chaperone-mediated protein folding
BHG40_18855	COG5002	protein histidine kinase activity
BHG40_18860	COG0745	RESPONSE REGULATOR receiver
BHG40_18865	COG0346	lactoylglutathione lyase activity
BHG40_18870	COG3706	GGDEF domain
BHG40_18875	COG3284	Transcriptional regulator
BHG40_18880	COG1012	belongs to the aldehyde dehydrogenase family
BHG40_18885	COG1942	4-Oxalocrotonate Tautomerase
BHG40_18890	COG2267	carboxylic ester hydrolase activity
BHG40_18910	COG0697	spore germination
BHG40_18920	COG0667	Aldo Keto reductase
BHG40_18935	COG3290	protein histidine kinase activity
BHG40_18940	COG0281	malic enzyme
BHG40_18960	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BHG40_18970	COG0281	malic enzyme
BHG40_18985	COG0437	4 iron, 4 sulfur cluster binding
BHG40_18990	COG3383	formate dehydrogenase (NAD+) activity
BHG40_19020	COG5433	transposase activity
BHG40_19035	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
BHG40_19045	COG3852	Histidine kinase
BHG40_19060	COG4662	Binding-protein-dependent transport system inner membrane component
BHG40_19070	COG0746	molybdenum cofactor guanylyltransferase activity
BHG40_19075	COG0303	'Molybdopterin
BHG40_19080	COG1289	transmembrane transporter activity
BHG40_19085	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
BHG40_19135	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BHG40_19140	COG0444	Belongs to the ABC transporter superfamily
BHG40_19145	COG4608	Belongs to the ABC transporter superfamily
BHG40_19155	COG2971	BadF BadG BcrA BcrD
BHG40_19165	COG0840	transmembrane signaling receptor activity
BHG40_19175	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
BHG40_19180	COG3724	N-succinylarginine dihydrolase activity
BHG40_19185	COG0616	signal peptide processing
BHG40_19190	COG1028	Short-chain dehydrogenase reductase Sdr
BHG40_19195	COG0583	DNA-binding transcription factor activity
BHG40_19205	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
BHG40_19215	COG0583	DNA-binding transcription factor activity
BHG40_19225	COG1881	PFAM PEBP family protein
BHG40_19235	COG0366	Alpha amylase catalytic
BHG40_19275	COG0037	tRNA processing
BHG40_19280	COG3590	peptidase
BHG40_19290	COG0488	(ABC) transporter
BHG40_19300	COG0531	amino acid
BHG40_19305	COG0814	amino acid
BHG40_19320	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
BHG40_19325	COG1982	Orn Lys Arg decarboxylase major
BHG40_19330	COG0531	amino acid
BHG40_19335	COG3710	Transcriptional regulator
BHG40_19340	COG0825	malonyl-CoA metabolic process
BHG40_19350	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
BHG40_19355	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
BHG40_19360	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
BHG40_19365	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
BHG40_19370	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
BHG40_19385	COG0750	zinc metalloprotease
BHG40_19390	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
BHG40_19395	COG0575	Belongs to the CDS family
BHG40_19400	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
BHG40_19405	COG0233	cytoplasmic translational termination
BHG40_19410	COG0528	UMP kinase activity
BHG40_19415	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
BHG40_19420	COG0052	Belongs to the universal ribosomal protein uS2 family
BHG40_19425	COG0024	Methionine aminopeptidase
BHG40_19430	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
BHG40_19435	COG2171	N-acyltransferase activity
BHG40_19445	COG1263	PTS System
BHG40_19445	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BHG40_19455	COG4580	involved in the transport of maltose and maltodextrins
BHG40_19460	COG5433	transposase activity
BHG40_19470	COG0564	pseudouridine synthase activity
BHG40_19475	COG3098	single-species biofilm formation
BHG40_19500	COG5595	Zn-ribbon-containing, possibly nucleic-acid-binding protein (DUF2310)
BHG40_19510	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
BHG40_19510	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
BHG40_19520	COG3706	GGDEF domain
BHG40_19525	COG1611	Belongs to the LOG family
BHG40_19530	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BHG40_19535	COG0473	3-isopropylmalate dehydrogenase activity
BHG40_19545	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
BHG40_19550	COG2363	Small membrane protein
BHG40_19560	COG0583	DNA-binding transcription factor activity
BHG40_19565	COG0840	transmembrane signaling receptor activity
BHG40_19570	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
BHG40_19585	COG1477	protein flavinylation
BHG40_19590	COG2871	sodium ion transport
BHG40_19595	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
BHG40_19600	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
BHG40_19605	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
BHG40_19610	COG1805	sodium ion transport
BHG40_19615	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
BHG40_19620	COG0271	Belongs to the BolA IbaG family
BHG40_19625	COG2813	Specifically methylates the guanine in position
BHG40_19635	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
BHG40_19645	COG2211	Major facilitator Superfamily
BHG40_19650	COG3248	Nucleoside-binding outer membrane protein
BHG40_19655	COG1666	GTP binding
BHG40_19660	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
BHG40_19665	COG0693	protein deglycase activity
BHG40_19685	COG3459	Glycosyltransferase 36 associated
BHG40_19695	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
BHG40_19695	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
BHG40_19700	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
BHG40_19710	COG1151	hydroxylamine reductase activity
BHG40_19715	COG0783	Belongs to the Dps family
BHG40_19740	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
BHG40_19755	COG0300	oxidoreductase activity
BHG40_19765	COG0415	Belongs to the DNA photolyase family
BHG40_19770	COG0789	Transcriptional regulator
BHG40_19775	COG3272	Protein of unknown function (DUF1722)
BHG40_19805	COG1605	Chorismate mutase
BHG40_19805	COG0077	Prephenate dehydratase
BHG40_19830	COG2133	pyrroloquinoline quinone binding
BHG40_19855	COG0300	oxidoreductase activity
BHG40_19880	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
BHG40_19895	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
BHG40_19905	COG3813	Protein conserved in bacteria
BHG40_19920	COG1280	lysine exporter protein (LysE YggA)
BHG40_19930	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BHG40_19935	COG0840	transmembrane signaling receptor activity
BHG40_19960	COG0835	chemotaxis
BHG40_19965	COG0840	transmembrane signaling receptor activity
BHG40_19995	COG5433	transposase activity
BHG40_20010	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BHG40_20015	COG1396	sequence-specific DNA binding
BHG40_20015	COG1917	Cupin 2, conserved barrel domain protein
BHG40_20030	COG0531	amino acid
BHG40_20040	COG0531	amino acid
BHG40_20045	COG1283	sodium-dependent phosphate transmembrane transporter activity
BHG40_20055	COG3384	dioxygenase
BHG40_20070	COG0813	purine-nucleoside phosphorylase activity
BHG40_20090	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
BHG40_20095	COG0083	homoserine kinase activity
BHG40_20105	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
BHG40_20110	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
BHG40_20125	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
BHG40_20135	COG0745	RESPONSE REGULATOR receiver
BHG40_20150	COG4988	ABC transporter
BHG40_20155	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
BHG40_20175	COG1720	tRNA m6t6A37 methyltransferase activity
BHG40_20195	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
BHG40_20200	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
BHG40_20210	COG2190	(PTS) system
BHG40_20215	COG3706	GGDEF domain
BHG40_20225	COG3038	cytochrome b561
BHG40_20235	COG5433	transposase activity
BHG40_20245	COG0419	ATPase involved in DNA repair
BHG40_20250	COG0420	3'-5' exonuclease activity
BHG40_20260	COG2974	May be involved in recombination
BHG40_20265	COG0405	Gamma-glutamyltransferase
BHG40_20270	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
BHG40_20270	COG4651	solute:proton antiporter activity
BHG40_20275	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
BHG40_20275	COG4651	solute:proton antiporter activity
BHG40_20290	COG0469	pyruvate kinase activity
BHG40_20295	COG3264	Mechanosensitive ion channel
BHG40_20295	COG1196	nuclear chromosome segregation
BHG40_20300	COG0582	viral genome integration into host DNA
BHG40_20310	COG1846	Transcriptional regulator
BHG40_20315	COG1566	PFAM secretion protein HlyD family protein
BHG40_20340	COG0602	queuosine metabolic process
BHG40_20350	COG1328	CTP reductase activity
BHG40_20360	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
BHG40_20365	COG3115	cell septum assembly
BHG40_20370	COG1196	nuclear chromosome segregation
BHG40_20380	COG2860	membrane
BHG40_20395	COG2989	Protein conserved in bacteria
BHG40_20410	COG0463	Glycosyl transferase, family 2
BHG40_20430	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
BHG40_20435	COG0739	heme binding
BHG40_20440	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
BHG40_20455	COG5433	transposase activity
BHG40_20460	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
BHG40_20470	COG3091	SprT-like family
BHG40_20480	COG1385	rRNA (uridine-N3-)-methyltransferase activity
BHG40_20485	COG0189	ligase activity
BHG40_20505	COG1678	Uncharacterized ACR, COG1678
BHG40_20510	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
BHG40_20515	COG0583	DNA-binding transcription factor activity
BHG40_20530	COG0714	Associated with various cellular activities
BHG40_20545	COG1115	amino acid carrier protein
BHG40_20550	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
BHG40_20565	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
BHG40_20585	COG1301	dicarboxylic acid transport
BHG40_20605	COG2912	Transglutaminase-like superfamily
BHG40_20615	COG2890	protein-(glutamine-N5) methyltransferase activity
BHG40_20620	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
BHG40_20625	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
BHG40_20630	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
BHG40_20645	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
BHG40_20650	COG0737	Belongs to the 5'-nucleotidase family
BHG40_20655	COG0193	aminoacyl-tRNA hydrolase activity
BHG40_20660	COG0012	GTP binding
BHG40_20705	COG0471	metal ion transport
BHG40_20705	COG0490	domain, Protein
BHG40_20715	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
BHG40_20750	COG0443	Heat shock 70 kDa protein
BHG40_20765	COG0366	Alpha amylase catalytic
BHG40_20780	COG0488	(ABC) transporter
BHG40_20800	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BHG40_20810	COG1012	belongs to the aldehyde dehydrogenase family
BHG40_20820	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
BHG40_20835	COG0180	Tryptophanyl-tRNA synthetase
BHG40_20840	COG0546	phosphoglycolate phosphatase activity
BHG40_20845	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
BHG40_20850	COG0338	D12 class N6 adenine-specific DNA methyltransferase
BHG40_20860	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
BHG40_20865	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
BHG40_20895	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
BHG40_20900	COG0583	DNA-binding transcription factor activity
BHG40_20905	COG0840	transmembrane signaling receptor activity
BHG40_20920	COG0583	DNA-binding transcription factor activity
BHG40_20935	COG0739	heme binding
BHG40_20965	COG0584	glycerophosphoryl diester phosphodiesterase
BHG40_20980	COG1053	succinate dehydrogenase
BHG40_20985	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
BHG40_20990	COG3029	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
BHG40_20995	COG3080	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
BHG40_21015	COG3214	Protein conserved in bacteria
BHG40_21050	COG0745	RESPONSE REGULATOR receiver
BHG40_21055	COG0642	Histidine kinase
BHG40_21065	COG0516	GMP reductase activity
BHG40_21075	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
BHG40_21085	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BHG40_21105	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BHG40_21120	COG3706	GGDEF domain
BHG40_21130	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BHG40_21135	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
BHG40_21140	COG1702	phosphate starvation-inducible protein PhoH
BHG40_21145	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
BHG40_21150	COG4535	Mg2 and Co2 transporter CorC
BHG40_21155	COG0815	Transfers the fatty acyl group on membrane lipoproteins
BHG40_21160	COG2888	peptidyl-tyrosine sulfation
BHG40_21165	COG0495	leucyl-tRNA aminoacylation
BHG40_21185	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
BHG40_21190	COG0799	negative regulation of ribosome biogenesis
BHG40_21195	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
BHG40_21200	COG0768	penicillin binding
BHG40_21205	COG0772	Belongs to the SEDS family
BHG40_21210	COG2951	lytic endotransglycosylase activity
BHG40_21215	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
BHG40_21220	COG1686	Belongs to the peptidase S11 family
BHG40_21225	COG2921	Belongs to the UPF0250 family
BHG40_21230	COG0321	lipoyl(octanoyl) transferase activity
BHG40_21235	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
BHG40_21250	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BHG40_21255	COG3545	Serine hydrolase
BHG40_21270	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
BHG40_21280	COG1970	mechanosensitive ion channel activity
BHG40_21285	COG3706	GGDEF domain
BHG40_21290	COG4974	Belongs to the 'phage' integrase family
BHG40_21295	COG0716	FMN binding
BHG40_21305	COG0312	modulator of DNA gyrase
BHG40_21350	COG5433	transposase activity
BHG40_21365	COG1422	Protein of unknown function (DUF1090)
BHG40_21370	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
BHG40_21375	COG3706	GGDEF domain
BHG40_21380	COG2211	Major facilitator Superfamily
BHG40_21385	COG1185	polyribonucleotide nucleotidyltransferase activity
BHG40_21390	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
BHG40_21395	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
BHG40_21400	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
BHG40_21405	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
BHG40_21410	COG0195	Participates in both transcription termination and antitermination
BHG40_21415	COG0779	Required for maturation of 30S ribosomal subunits
BHG40_21430	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
BHG40_21435	COG0149	triose-phosphate isomerase activity
BHG40_21440	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
BHG40_21445	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
BHG40_21450	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
BHG40_21455	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
BHG40_21460	COG1534	Rna-binding protein
BHG40_21470	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
BHG40_21485	COG1360	Flagellar Motor Protein
BHG40_21490	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
BHG40_21495	COG1722	exodeoxyribonuclease VII activity
BHG40_21500	COG0142	geranyltranstransferase activity
BHG40_21505	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
BHG40_21530	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
BHG40_21535	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
BHG40_21540	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
BHG40_21545	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
BHG40_21560	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BHG40_21560	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BHG40_21565	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
BHG40_21580	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
BHG40_21600	COG3381	protein complex oligomerization
BHG40_21630	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BHG40_21635	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
BHG40_21640	COG0511	ligase activity, forming carbon-carbon bonds
BHG40_21645	COG0439	Biotin carboxylase
BHG40_21650	COG3924	membrane
BHG40_21655	COG4145	pantothenate transmembrane transporter activity
BHG40_21660	COG2190	(PTS) system
BHG40_21660	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BHG40_21660	COG1263	PTS System
BHG40_21665	COG0583	DNA-binding transcription factor activity
BHG40_21670	COG0604	alcohol dehydrogenase
BHG40_21675	COG2264	protein methyltransferase activity
BHG40_21680	COG0531	amino acid
BHG40_21685	COG4303	Ethanolamine ammonia lyase large subunit
BHG40_21690	COG4302	ethanolamine ammonia-lyase activity
BHG40_21710	COG0778	Nitroreductase
BHG40_21715	COG0446	pyridine nucleotide-disulphide oxidoreductase
BHG40_21715	COG1902	pentaerythritol trinitrate reductase activity
BHG40_21720	COG0616	signal peptide processing
BHG40_21740	COG3139	Protein of unknown function (DUF1315)
BHG40_21745	COG0252	asparaginase activity
BHG40_21750	COG0786	glutamate:sodium symporter activity
BHG40_21760	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
BHG40_21765	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
BHG40_21770	COG0384	phenazine biosynthesis protein PhzF
BHG40_21775	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
BHG40_21780	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BHG40_21785	COG0175	sulfate reduction
BHG40_21790	COG2113	Glycine betaine
BHG40_21795	COG4176	ABC-type proline glycine betaine transport system permease component
BHG40_21800	COG4175	Glycine betaine
BHG40_21810	COG3610	response to peptide
BHG40_21815	COG2966	Psort location CytoplasmicMembrane, score
BHG40_21830	COG0521	Mo-molybdopterin cofactor biosynthetic process
BHG40_21840	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
BHG40_21845	COG1028	Short-chain dehydrogenase reductase Sdr
BHG40_21855	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
BHG40_21880	COG2986	histidine ammonia-lyase
BHG40_21895	COG0318	PFAM AMP-dependent synthetase and ligase
BHG40_21905	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BHG40_21910	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BHG40_21955	COG1858	cytochrome C peroxidase
BHG40_21970	COG2313	pseudouridylate synthase activity
BHG40_21975	COG1522	sequence-specific DNA binding
BHG40_21975	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BHG40_22005	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
BHG40_22010	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
BHG40_22025	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
BHG40_22030	COG4974	Belongs to the 'phage' integrase family
BHG40_22115	COG2176	DNA-directed DNA polymerase activity
BHG40_22115	COG5002	protein histidine kinase activity
BHG40_22160	COG4695	Portal protein
BHG40_22260	COG2003	Belongs to the UPF0758 family
BHG40_22295	COG3039	Transposase
BHG40_22440	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
BHG40_22445	COG2361	Protein of unknown function DUF86
BHG40_22465	COG1192	Involved in chromosome partitioning
BHG40_22565	COG2916	Histone family protein nucleoid-structuring protein H-NS
BHG40_22575	COG3328	transposase activity
BHG40_22605	COG1317	bacterial-type flagellum organization
BHG40_22700	COG0457	Tetratricopeptide repeat
BHG40_22765	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
BHG40_22770	COG4790	Type iii secretion
BHG40_22775	COG4794	Type iii secretion
BHG40_22780	COG4791	protein targeting
BHG40_22785	COG4792	protein secretion
BHG40_22815	COG1192	Involved in chromosome partitioning
BHG40_22825	COG1484	DNA-dependent DNA replication