locus-tag	class	description
G9457_00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
G9457_00010	COG0592	DNA-directed DNA polymerase activity
G9457_00035	COG2378	regulation of single-species biofilm formation
G9457_00040	COG0071	Belongs to the small heat shock protein (HSP20) family
G9457_00045	COG0071	Belongs to the small heat shock protein (HSP20) family
G9457_00060	COG3977	Valine--pyruvate aminotransferase
G9457_00075	COG2814	Major facilitator Superfamily
G9457_00085	COG0745	RESPONSE REGULATOR receiver
G9457_00090	COG2205	protein histidine kinase activity
G9457_00110	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
G9457_00115	COG4191	Histidine kinase
G9457_00115	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
G9457_00120	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
G9457_00125	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
G9457_00130	COG1309	transcriptional regulator
G9457_00160	COG0561	phosphatase activity
G9457_00165	COG2267	carboxylic ester hydrolase activity
G9457_00170	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
G9457_00175	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
G9457_00180	COG1758	RNA polymerase activity
G9457_00185	COG0194	GDP metabolic process
G9457_00195	COG0859	PFAM glycosyl transferase family 9
G9457_00200	COG3642	lipopolysaccharide core region biosynthetic process
G9457_00240	COG0589	response to stress
G9457_00245	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
G9457_00255	COG1528	Iron-storage protein
G9457_00260	COG2081	HI0933 family
G9457_00310	COG5433	transposase activity
G9457_00315	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
G9457_00315	COG2205	protein histidine kinase activity
G9457_00325	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
G9457_00325	COG2205	protein histidine kinase activity
G9457_00335	COG3275	phosphorelay sensor kinase activity
G9457_00340	COG3279	Response regulator of the LytR AlgR family
G9457_00345	COG2223	nitrite transmembrane transporter activity
G9457_00350	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
G9457_00355	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
G9457_00370	COG0583	DNA-binding transcription factor activity
G9457_00375	COG4206	TonB-dependent receptor
G9457_00380	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
G9457_00425	COG0583	DNA-binding transcription factor activity
G9457_00430	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
G9457_00435	COG0166	Belongs to the GPI family
G9457_00445	COG0668	transmembrane transport
G9457_00450	COG1309	transcriptional regulator
G9457_00455	COG0756	dUTP diphosphatase activity
G9457_00460	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
G9457_00465	COG2003	Belongs to the UPF0758 family
G9457_00470	COG0227	Belongs to the bacterial ribosomal protein bL28 family
G9457_00475	COG0267	Belongs to the bacterial ribosomal protein bL33 family
G9457_00485	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
G9457_00490	COG2990	Protein conserved in bacteria
G9457_00495	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
G9457_00500	COG0859	PFAM glycosyl transferase family 9
G9457_00505	COG0463	Glycosyl transferase, family 2
G9457_00510	COG0859	PFAM glycosyl transferase family 9
G9457_00515	COG1519	Transferase
G9457_00530	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
G9457_00535	COG1609	Transcriptional regulator
G9457_00565	COG1580	Controls the rotational direction of flagella during chemotaxis
G9457_00570	COG3161	chorismate lyase activity
G9457_00575	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
G9457_00580	COG2937	Belongs to the GPAT DAPAT family
G9457_00585	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
G9457_00600	COG0534	Mate efflux family protein
G9457_00605	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
G9457_00610	COG2205	protein histidine kinase activity
G9457_00615	COG0745	RESPONSE REGULATOR receiver
G9457_00625	COG1045	serine acetyltransferase
G9457_00635	COG3074	FtsZ-dependent cytokinesis
G9457_00640	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
G9457_00655	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
G9457_00700	COG1609	Transcriptional regulator
G9457_00705	COG0385	Bile acid
G9457_00710	COG1262	PFAM Formylglycine-generating sulfatase enzyme
G9457_00730	COG0583	DNA-binding transcription factor activity
G9457_00735	COG1079	Belongs to the binding-protein-dependent transport system permease family
G9457_00740	COG4603	Belongs to the binding-protein-dependent transport system permease family
G9457_00745	COG3845	ABC transporter
G9457_00750	COG1744	ABC transporter substrate-binding protein PnrA-like
G9457_00755	COG0210	DNA helicase
G9457_00795	COG2391	methyltransferase activity
G9457_00800	COG5433	transposase activity
G9457_00810	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
G9457_00825	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
G9457_00830	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
G9457_00840	COG0018	arginyl-trna synthetase
G9457_00850	COG1595	DNA-templated transcription, initiation
G9457_00860	COG1968	undecaprenyl-diphosphatase activity
G9457_00865	COG0667	Aldo Keto reductase
G9457_00870	COG2017	converts alpha-aldose to the beta-anomer
G9457_00875	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
G9457_00885	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
G9457_00890	COG1609	Transcriptional regulator
G9457_00895	COG3250	beta-galactosidase activity
G9457_00910	COG4211	Belongs to the binding-protein-dependent transport system permease family
G9457_00960	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
G9457_00965	COG1288	antiporter activity
G9457_00975	COG1438	arginine binding
G9457_00980	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
G9457_00985	COG0540	Belongs to the ATCase OTCase family
G9457_01010	COG3040	lipid binding
G9457_01020	COG1979	alcohol dehydrogenase
G9457_01045	COG2964	Protein conserved in bacteria
G9457_01050	COG3681	Belongs to the UPF0597 family
G9457_01060	COG0446	pyridine nucleotide-disulphide oxidoreductase
G9457_01065	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
G9457_01070	COG0564	pseudouridine synthase activity
G9457_01080	COG0542	response to heat
G9457_01085	COG2502	aspartate--ammonia ligase
G9457_01090	COG1522	sequence-specific DNA binding
G9457_01100	COG5413	integral membrane protein
G9457_01105	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
G9457_01105	COG0617	tRNA 3'-terminal CCA addition
G9457_01105	COG0517	IMP dehydrogenase activity
G9457_01110	COG1028	Short-chain dehydrogenase reductase Sdr
G9457_01125	COG2205	protein histidine kinase activity
G9457_01135	COG2204	response regulator
G9457_01145	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
G9457_01150	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
G9457_01180	COG0243	molybdopterin cofactor binding
G9457_01185	COG3005	denitrification pathway
G9457_01190	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
G9457_01195	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
G9457_01200	COG0569	domain protein
G9457_01205	COG0812	UDP-N-acetylmuramate dehydrogenase activity
G9457_01230	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
G9457_01245	COG0250	Participates in transcription elongation, termination and antitermination
G9457_01250	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
G9457_01255	COG0081	regulation of translation
G9457_01260	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
G9457_01265	COG0222	ribosome binding
G9457_01270	COG0085	RNA polymerase activity
G9457_01275	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
G9457_01280	COG2964	Protein conserved in bacteria
G9457_01295	COG2923	Belongs to the DsrF TusC family
G9457_01300	COG2168	tRNA wobble position uridine thiolation
G9457_01305	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
G9457_01310	COG0049	tRNA binding
G9457_01315	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
G9457_01320	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
G9457_01325	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
G9457_01385	COG3047	cAMP biosynthetic process
G9457_01415	COG3135	benzoate transporter
G9457_01420	COG1396	sequence-specific DNA binding
G9457_01450	COG2926	Belongs to the UPF0265 family
G9457_01460	COG3028	Belongs to the UPF0307 family
G9457_01465	COG0312	modulator of DNA gyrase
G9457_01470	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
G9457_01475	COG5007	Belongs to the BolA IbaG family
G9457_01485	COG2854	intermembrane phospholipid transfer
G9457_01490	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
G9457_01495	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
G9457_01500	COG1127	ABC transporter
G9457_01505	COG0517	IMP dehydrogenase activity
G9457_01505	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
G9457_01510	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
G9457_01515	COG3117	lipopolysaccharide transmembrane transporter activity
G9457_01520	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
G9457_01525	COG1137	ATPase activity
G9457_01530	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
G9457_01540	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
G9457_01545	COG1660	Displays ATPase and GTPase activities
G9457_01550	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
G9457_01575	COG3964	amidohydrolase
G9457_01610	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
G9457_01615	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
G9457_01625	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
G9457_01630	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
G9457_01635	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
G9457_01640	COG0723	plastoquinol--plastocyanin reductase activity
G9457_01645	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
G9457_01650	COG2857	Cytochrome c1
G9457_01655	COG0625	glutathione transferase activity
G9457_01660	COG2969	positive regulation of protein catabolic process
G9457_01665	COG2823	Periplasmic or secreted lipoprotein
G9457_01670	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
G9457_01680	COG3107	peptidoglycan biosynthetic process
G9457_01685	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
G9457_01710	COG1987	bacterial-type flagellum assembly
G9457_01760	COG2249	NAD(P)H dehydrogenase (quinone) activity
G9457_01775	COG1770	oligopeptidase
G9457_01795	COG3714	YhhN family
G9457_01820	COG1301	dicarboxylic acid transport
G9457_01830	COG2095	MarC family integral membrane protein
G9457_01840	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
G9457_01850	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
G9457_01860	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
G9457_01890	COG0742	ribosomal rna small subunit methyltransferase
G9457_01895	COG0552	protein localization to endoplasmic reticulum
G9457_01900	COG2884	Cell division ATP-binding protein ftsE
G9457_01905	COG2177	Part of the ABC transporter FtsEX involved in
G9457_01915	COG0288	reversible hydration of carbon dioxide
G9457_01920	COG2188	Transcriptional regulator
G9457_01925	COG1228	amidohydrolase
G9457_01930	COG0010	Belongs to the arginase family
G9457_01935	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
G9457_01940	COG2986	histidine ammonia-lyase
G9457_01945	COG0387	Pfam Sodium calcium exchanger
G9457_01950	COG2264	protein methyltransferase activity
G9457_01955	COG2199	diguanylate cyclase activity
G9457_01955	COG2200	EAL domain
G9457_02015	COG1077	Cell shape determining protein MreB Mrl
G9457_02020	COG1792	Involved in formation and maintenance of cell shape
G9457_02025	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
G9457_02030	COG0424	maF-like protein
G9457_02035	COG1530	ribonuclease E activity
G9457_02040	COG3164	Protein of unknown function
G9457_02050	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
G9457_02055	COG0312	modulator of DNA gyrase
G9457_02070	COG0477	Major facilitator Superfamily
G9457_02080	COG3437	response regulator, receiver
G9457_02085	COG0784	Response regulator, receiver
G9457_02085	COG2205	protein histidine kinase activity
G9457_02085	COG5002	protein histidine kinase activity
G9457_02090	COG2172	sigma factor antagonist activity
G9457_02095	COG1366	Belongs to the anti-sigma-factor antagonist family
G9457_02105	COG3700	Belongs to the class B bacterial acid phosphatase family
G9457_02115	COG1639	'signal transduction protein
G9457_02140	COG0189	ligase activity
G9457_02150	COG0745	RESPONSE REGULATOR receiver
G9457_02195	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
G9457_02210	COG2165	general secretion pathway protein
G9457_02225	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
G9457_02235	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
G9457_02240	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
G9457_02245	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
G9457_02250	COG0813	purine-nucleoside phosphorylase activity
G9457_02260	COG0560	Phosphoserine phosphatase
G9457_02285	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
G9457_02290	COG0776	regulation of translation
G9457_02305	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
G9457_02310	COG0735	belongs to the Fur family
G9457_02330	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
G9457_02335	COG0513	Belongs to the DEAD box helicase family
G9457_02340	COG3022	response to hydroperoxide
G9457_02355	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
G9457_02360	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
G9457_02365	COG0762	integral membrane protein
G9457_02370	COG1872	DUF167
G9457_02385	COG4166	transmembrane transport
G9457_02395	COG0110	maltose O-acetyltransferase activity
G9457_02405	COG1024	Enoyl-CoA hydratase
G9457_02420	COG4221	oxidoreductase activity
G9457_02430	COG2957	Belongs to the agmatine deiminase family
G9457_02550	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
G9457_02555	COG0352	thiamine-phosphate diphosphorylase activity
G9457_02560	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
G9457_02570	COG2022	thiamine diphosphate biosynthetic process
G9457_02600	COG5433	transposase activity
G9457_02605	COG0814	amino acid
G9457_02610	COG3932	Exopolysaccharide synthesis, ExoD
G9457_02660	COG1494	fructose-1,6-bisphosphatase
G9457_02675	COG2959	enzyme of heme biosynthesis
G9457_02685	COG0181	hydroxymethylbilane synthase activity
G9457_02690	COG3072	Adenylate cyclase
G9457_02695	COG0400	carboxylic ester hydrolase activity
G9457_02700	COG1965	Belongs to the frataxin family
G9457_02710	COG0019	diaminopimelate decarboxylase activity
G9457_02715	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
G9457_02730	COG1011	Hydrolase
G9457_02740	COG0668	transmembrane transport
G9457_02750	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
G9457_02755	COG0561	phosphatase activity
G9457_02780	COG0842	Transport permease protein
G9457_02780	COG1129	ABC transporter
G9457_02790	COG1058	Belongs to the CinA family
G9457_02790	COG1546	Belongs to the CinA family
G9457_02795	COG1418	mRNA catabolic process
G9457_02800	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
G9457_02810	COG1522	sequence-specific DNA binding
G9457_02815	COG1368	sulfuric ester hydrolase activity
G9457_02835	COG1285	pathogenesis
G9457_02855	COG4221	oxidoreductase activity
G9457_02875	COG1979	alcohol dehydrogenase
G9457_02885	COG2873	o-acetylhomoserine
G9457_02920	COG5380	lipid catabolic process
G9457_02940	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
G9457_02945	COG2949	membrane
G9457_02950	COG3291	Pkd domain containing protein
G9457_02960	COG5433	transposase activity
G9457_03020	COG5433	transposase activity
G9457_03030	COG0318	PFAM AMP-dependent synthetase and ligase
G9457_03040	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
G9457_03045	COG0596	Alpha beta hydrolase
G9457_03050	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
G9457_03055	COG1169	isochorismate synthase
G9457_03060	COG1575	Belongs to the MenA family. Type 1 subfamily
G9457_03085	COG0513	Belongs to the DEAD box helicase family
G9457_03095	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
G9457_03100	COG1988	membrane-bound metal-dependent
G9457_03115	COG1671	Belongs to the UPF0178 family
G9457_03135	COG0484	heat shock protein binding
G9457_03140	COG3263	regulation of cellular component size
G9457_03150	COG0246	Mannitol dehydrogenase
G9457_03155	COG2213	PTS system mannitol-specific
G9457_03155	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
G9457_03170	COG4776	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction
G9457_03185	COG2771	luxR family
G9457_03200	COG3133	Outer membrane lipoprotein
G9457_03205	COG0456	acetyltransferase
G9457_03225	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
G9457_03230	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
G9457_03250	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
G9457_03255	COG1459	type II secretion system
G9457_03260	COG2165	general secretion pathway protein
G9457_03270	COG2165	general secretion pathway protein
G9457_03275	COG4795	General secretion pathway protein
G9457_03280	COG3156	type II secretion system protein K
G9457_03290	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
G9457_03305	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
G9457_03310	COG1011	Hydrolase
G9457_03315	COG0494	nUDIX hydrolase
G9457_03320	COG1218	3'(2'),5'-bisphosphate nucleotidase
G9457_03325	COG0814	amino acid
G9457_03330	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
G9457_03345	COG0626	cystathionine gamma-synthase activity
G9457_03350	COG0527	aspartate kinase activity
G9457_03350	COG0460	homoserine dehydrogenase
G9457_03365	COG1346	cytolysis
G9457_03405	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
G9457_03410	COG1546	Belongs to the CinA family
G9457_03415	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
G9457_03425	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
G9457_03430	COG0527	aspartate kinase activity
G9457_03435	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
G9457_03460	COG1686	Belongs to the peptidase S11 family
G9457_03465	COG0586	Pfam SNARE associated Golgi protein
G9457_03480	COG2927	DNA polymerase III (CHI subunit)
G9457_03485	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
G9457_03490	COG0795	lipopolysaccharide-transporting ATPase activity
G9457_03495	COG0795	lipopolysaccharide-transporting ATPase activity
G9457_03510	COG0582	viral genome integration into host DNA
G9457_03650	COG0513	Belongs to the DEAD box helicase family
G9457_03670	COG1912	Pfam S-adenosyl-l-methionine hydroxide adenosyltransferase
G9457_03735	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
G9457_03750	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
G9457_03780	COG0745	RESPONSE REGULATOR receiver
G9457_03785	COG3104	oligopeptide transport
G9457_03790	COG1210	Utp--glucose-1-phosphate uridylyltransferase
G9457_03795	COG1555	photosystem II stabilization
G9457_03805	COG2350	Protein conserved in bacteria
G9457_03810	COG2917	probably involved in intracellular septation
G9457_03815	COG0076	glutamate decarboxylase activity
G9457_03820	COG1272	protein, Hemolysin III
G9457_03825	COG0569	domain protein
G9457_03825	COG2985	domain, Protein
G9457_03840	COG0784	Response regulator, receiver
G9457_03840	COG0835	chemotaxis
G9457_03845	COG2755	lipolytic protein G-D-S-L family
G9457_03850	COG4181	ATPase activity
G9457_03855	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
G9457_03860	COG1090	epimerase
G9457_03865	COG2200	EAL domain
G9457_03870	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
G9457_03875	COG2234	aminopeptidase activity
G9457_03875	COG4935	Belongs to the peptidase S8 family
G9457_03880	COG0220	tRNA (guanine-N7-)-methyltransferase activity
G9457_03885	COG3171	Protein conserved in bacteria
G9457_03890	COG2066	Belongs to the glutaminase family
G9457_03895	COG2897	thiosulfate sulfurtransferase activity
G9457_03920	COG1012	belongs to the aldehyde dehydrogenase family
G9457_03925	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
G9457_03955	COG3076	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome
G9457_03960	COG5001	Diguanylate cyclase
G9457_03960	COG3300	MHYT domain
G9457_03980	COG4628	conserved protein (DUF2132)
G9457_03985	COG0688	phosphatidylethanolamine metabolic process
G9457_03995	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
G9457_04035	COG1278	Cold shock
G9457_04050	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
G9457_04105	COG0848	biopolymer transport protein
G9457_04110	COG0811	peptide transport
G9457_04115	COG0811	peptide transport
G9457_04125	COG4206	TonB-dependent receptor
G9457_04130	COG5433	transposase activity
G9457_04150	COG4239	(ABC) transporter, permease
G9457_04155	COG0747	negative chemotaxis
G9457_04160	COG0444	Belongs to the ABC transporter superfamily
G9457_04165	COG4608	Belongs to the ABC transporter superfamily
G9457_04170	COG2195	Cleaves the N-terminal amino acid of tripeptides
G9457_04180	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
G9457_04185	COG1073	alpha beta
G9457_04195	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
G9457_04200	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
G9457_04230	COG1522	sequence-specific DNA binding
G9457_04230	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
G9457_04235	COG2313	pseudouridylate synthase activity
G9457_04245	COG5433	transposase activity
G9457_04250	COG1858	cytochrome C peroxidase
G9457_04295	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
G9457_04300	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
G9457_04310	COG0318	PFAM AMP-dependent synthetase and ligase
G9457_04325	COG2986	histidine ammonia-lyase
G9457_04350	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
G9457_04360	COG1028	Short-chain dehydrogenase reductase Sdr
G9457_04365	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
G9457_04375	COG0521	Mo-molybdopterin cofactor biosynthetic process
G9457_04390	COG2966	Psort location CytoplasmicMembrane, score
G9457_04395	COG3610	response to peptide
G9457_04405	COG4175	Glycine betaine
G9457_04410	COG4176	ABC-type proline glycine betaine transport system permease component
G9457_04415	COG2113	Glycine betaine
G9457_04420	COG0175	sulfate reduction
G9457_04425	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
G9457_04430	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
G9457_04435	COG0384	phenazine biosynthesis protein PhzF
G9457_04440	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
G9457_04455	COG0786	glutamate:sodium symporter activity
G9457_04460	COG0252	asparaginase activity
G9457_04465	COG3139	Protein of unknown function (DUF1315)
G9457_04525	COG0531	amino acid
G9457_04535	COG0604	alcohol dehydrogenase
G9457_04550	COG4145	pantothenate transmembrane transporter activity
G9457_04555	COG3924	membrane
G9457_04560	COG0439	Biotin carboxylase
G9457_04570	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
G9457_04575	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
G9457_04605	COG3381	protein complex oligomerization
G9457_04620	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
G9457_04635	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
G9457_04640	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
G9457_04640	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
G9457_04655	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
G9457_04660	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
G9457_04665	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
G9457_04670	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
G9457_04675	COG4172	Belongs to the ABC transporter superfamily
G9457_04685	COG0601	transmembrane transport
G9457_04695	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
G9457_04700	COG0142	geranyltranstransferase activity
G9457_04705	COG1722	exodeoxyribonuclease VII activity
G9457_04710	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
G9457_04715	COG1360	Flagellar Motor Protein
G9457_04740	COG1534	Rna-binding protein
G9457_04745	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
G9457_04755	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
G9457_04760	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
G9457_04765	COG0149	triose-phosphate isomerase activity
G9457_04770	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
G9457_04785	COG0779	Required for maturation of 30S ribosomal subunits
G9457_04790	COG0195	Participates in both transcription termination and antitermination
G9457_04795	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
G9457_04800	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
G9457_04805	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
G9457_04810	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
G9457_04815	COG1185	polyribonucleotide nucleotidyltransferase activity
G9457_04820	COG2211	Major facilitator Superfamily
G9457_04825	COG3706	GGDEF domain
G9457_04830	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
G9457_04835	COG1422	Protein of unknown function (DUF1090)
G9457_04850	COG5433	transposase activity
G9457_04895	COG0312	modulator of DNA gyrase
G9457_04910	COG4974	Belongs to the 'phage' integrase family
G9457_04920	COG1970	mechanosensitive ion channel activity
G9457_04930	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
G9457_04945	COG3545	Serine hydrolase
G9457_04950	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
G9457_04970	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
G9457_04975	COG0321	lipoyl(octanoyl) transferase activity
G9457_04980	COG2921	Belongs to the UPF0250 family
G9457_04985	COG1686	Belongs to the peptidase S11 family
G9457_04990	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
G9457_04995	COG2951	lytic endotransglycosylase activity
G9457_05000	COG0772	Belongs to the SEDS family
G9457_05005	COG0768	penicillin binding
G9457_05010	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
G9457_05015	COG0799	negative regulation of ribosome biogenesis
G9457_05020	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
G9457_05040	COG0495	leucyl-tRNA aminoacylation
G9457_05045	COG2888	peptidyl-tyrosine sulfation
G9457_05050	COG0815	Transfers the fatty acyl group on membrane lipoproteins
G9457_05055	COG4535	Mg2 and Co2 transporter CorC
G9457_05060	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
G9457_05065	COG1702	phosphate starvation-inducible protein PhoH
G9457_05070	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
G9457_05075	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
G9457_05085	COG3706	GGDEF domain
G9457_05100	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
G9457_05120	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
G9457_05130	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
G9457_05140	COG0516	GMP reductase activity
G9457_05150	COG0642	Histidine kinase
G9457_05190	COG3214	Protein conserved in bacteria
G9457_05210	COG3080	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
G9457_05215	COG3029	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
G9457_05220	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
G9457_05225	COG1053	succinate dehydrogenase
G9457_05235	COG0584	glycerophosphoryl diester phosphodiesterase
G9457_05265	COG0739	heme binding
G9457_05280	COG0583	DNA-binding transcription factor activity
G9457_05295	COG0840	transmembrane signaling receptor activity
G9457_05300	COG0583	DNA-binding transcription factor activity
G9457_05305	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
G9457_05335	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
G9457_05340	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
G9457_05350	COG0338	D12 class N6 adenine-specific DNA methyltransferase
G9457_05355	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
G9457_05360	COG0546	phosphoglycolate phosphatase activity
G9457_05365	COG0180	Tryptophanyl-tRNA synthetase
G9457_05380	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
G9457_05390	COG1012	belongs to the aldehyde dehydrogenase family
G9457_05400	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
G9457_05420	COG0488	(ABC) transporter
G9457_05435	COG0366	Alpha amylase catalytic
G9457_05450	COG0443	Heat shock 70 kDa protein
G9457_05485	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
G9457_05495	COG0471	metal ion transport
G9457_05495	COG0490	domain, Protein
G9457_05540	COG0012	GTP binding
G9457_05545	COG0193	aminoacyl-tRNA hydrolase activity
G9457_05550	COG0737	Belongs to the 5'-nucleotidase family
G9457_05555	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
G9457_05565	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
G9457_05570	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
G9457_05575	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
G9457_05580	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
G9457_05585	COG2890	protein-(glutamine-N5) methyltransferase activity
G9457_05595	COG2912	Transglutaminase-like superfamily
G9457_05650	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
G9457_05655	COG1115	amino acid carrier protein
G9457_05670	COG0714	Associated with various cellular activities
G9457_05690	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
G9457_05695	COG1678	Uncharacterized ACR, COG1678
G9457_05715	COG0189	ligase activity
G9457_05720	COG1385	rRNA (uridine-N3-)-methyltransferase activity
G9457_05730	COG3091	SprT-like family
G9457_05740	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
G9457_05745	COG5433	transposase activity
G9457_05765	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
G9457_05770	COG0739	heme binding
G9457_05775	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
G9457_05795	COG0463	Glycosyl transferase, family 2
G9457_05810	COG2989	Protein conserved in bacteria
G9457_05815	COG3108	Peptidase M15
G9457_05825	COG2860	membrane
G9457_05835	COG1196	nuclear chromosome segregation
G9457_05840	COG3115	cell septum assembly
G9457_05845	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
G9457_05870	COG0602	queuosine metabolic process
G9457_05895	COG1566	PFAM secretion protein HlyD family protein
G9457_05900	COG1846	Transcriptional regulator
G9457_05915	COG0582	viral genome integration into host DNA
G9457_05920	COG3264	Mechanosensitive ion channel
G9457_05920	COG1196	nuclear chromosome segregation
G9457_05925	COG0469	pyruvate kinase activity
G9457_05940	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
G9457_05940	COG4651	solute:proton antiporter activity
G9457_05945	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
G9457_05945	COG4651	solute:proton antiporter activity
G9457_05950	COG0405	Gamma-glutamyltransferase
G9457_05955	COG2974	May be involved in recombination
G9457_05965	COG0420	3'-5' exonuclease activity
G9457_05970	COG0419	ATPase involved in DNA repair
G9457_05980	COG5433	transposase activity
G9457_05990	COG3038	cytochrome b561
G9457_06005	COG2190	(PTS) system
G9457_06015	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
G9457_06020	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
G9457_06040	COG1720	tRNA m6t6A37 methyltransferase activity
G9457_06060	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
G9457_06065	COG4988	ABC transporter
G9457_06080	COG0745	RESPONSE REGULATOR receiver
G9457_06090	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
G9457_06105	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
G9457_06110	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
G9457_06120	COG0083	homoserine kinase activity
G9457_06125	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
G9457_06160	COG0813	purine-nucleoside phosphorylase activity
G9457_06175	COG3384	dioxygenase
G9457_06185	COG1283	sodium-dependent phosphate transmembrane transporter activity
G9457_06190	COG0531	amino acid
G9457_06195	COG0531	amino acid
G9457_06210	COG1917	Cupin 2, conserved barrel domain protein
G9457_06210	COG1396	sequence-specific DNA binding
G9457_06215	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
G9457_06225	COG2169	Transcriptional regulator
G9457_06225	COG1917	Cupin 2, conserved barrel domain protein
G9457_06230	COG5433	transposase activity
G9457_06260	COG0840	transmembrane signaling receptor activity
G9457_06265	COG0835	chemotaxis
G9457_06285	COG0745	RESPONSE REGULATOR receiver
G9457_06295	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
G9457_06305	COG1280	lysine exporter protein (LysE YggA)
G9457_06320	COG3813	Protein conserved in bacteria
G9457_06330	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
G9457_06345	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
G9457_06370	COG0300	oxidoreductase activity
G9457_06400	COG2133	pyrroloquinoline quinone binding
G9457_06425	COG0077	Prephenate dehydratase
G9457_06425	COG1605	Chorismate mutase
G9457_06455	COG3272	Protein of unknown function (DUF1722)
G9457_06460	COG0789	Transcriptional regulator
G9457_06465	COG0415	Belongs to the DNA photolyase family
G9457_06475	COG0300	oxidoreductase activity
G9457_06490	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
G9457_06515	COG0783	Belongs to the Dps family
G9457_06520	COG1151	hydroxylamine reductase activity
G9457_06530	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
G9457_06535	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
G9457_06535	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
G9457_06565	COG0693	protein deglycase activity
G9457_06570	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
G9457_06575	COG1666	GTP binding
G9457_06580	COG3248	Nucleoside-binding outer membrane protein
G9457_06585	COG2211	Major facilitator Superfamily
G9457_06595	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
G9457_06605	COG2813	Specifically methylates the guanine in position
G9457_06610	COG0271	Belongs to the BolA IbaG family
G9457_06620	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
G9457_06625	COG1805	sodium ion transport
G9457_06630	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
G9457_06635	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
G9457_06640	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
G9457_06645	COG2871	sodium ion transport
G9457_06650	COG1477	protein flavinylation
G9457_06665	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
G9457_06670	COG0840	transmembrane signaling receptor activity
G9457_06675	COG0583	DNA-binding transcription factor activity
G9457_06685	COG2363	Small membrane protein
G9457_06690	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
G9457_06700	COG0473	3-isopropylmalate dehydrogenase activity
G9457_06705	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
G9457_06710	COG1611	Belongs to the LOG family
G9457_06725	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
G9457_06725	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
G9457_06735	COG5595	Zn-ribbon-containing, possibly nucleic-acid-binding protein (DUF2310)
G9457_06760	COG3098	single-species biofilm formation
G9457_06765	COG0564	pseudouridine synthase activity
G9457_06775	COG5433	transposase activity
G9457_06780	COG4580	involved in the transport of maltose and maltodextrins
G9457_06790	COG1263	PTS System
G9457_06790	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
G9457_06800	COG2171	N-acyltransferase activity
G9457_06805	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
G9457_06810	COG0024	Methionine aminopeptidase
G9457_06815	COG0052	Belongs to the universal ribosomal protein uS2 family
G9457_06820	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
G9457_06825	COG0528	UMP kinase activity
G9457_06830	COG0233	cytoplasmic translational termination
G9457_06835	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
G9457_06840	COG0575	Belongs to the CDS family
G9457_06845	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
G9457_06850	COG0750	zinc metalloprotease
G9457_06865	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
G9457_06870	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
G9457_06875	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
G9457_06880	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
G9457_06885	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
G9457_06895	COG0825	malonyl-CoA metabolic process
G9457_06900	COG3710	Transcriptional regulator
G9457_06905	COG0531	amino acid
G9457_06910	COG1982	Orn Lys Arg decarboxylase major
G9457_06915	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
G9457_06930	COG0814	amino acid
G9457_06935	COG0531	amino acid
G9457_06945	COG0488	(ABC) transporter
G9457_06955	COG3590	peptidase
G9457_06960	COG0037	tRNA processing
G9457_07010	COG0366	Alpha amylase catalytic
G9457_07020	COG1881	PFAM PEBP family protein
G9457_07025	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
G9457_07030	COG0583	DNA-binding transcription factor activity
G9457_07050	COG0583	DNA-binding transcription factor activity
G9457_07055	COG1028	Short-chain dehydrogenase reductase Sdr
G9457_07060	COG0616	signal peptide processing
G9457_07065	COG3724	N-succinylarginine dihydrolase activity
G9457_07085	COG0840	transmembrane signaling receptor activity
G9457_07095	COG2971	BadF BadG BcrA BcrD
G9457_07105	COG4608	Belongs to the ABC transporter superfamily
G9457_07110	COG0444	Belongs to the ABC transporter superfamily
G9457_07115	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
G9457_07165	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
G9457_07170	COG1289	transmembrane transporter activity
G9457_07175	COG0303	'Molybdopterin
G9457_07180	COG0746	molybdenum cofactor guanylyltransferase activity
G9457_07190	COG4662	Binding-protein-dependent transport system inner membrane component
G9457_07205	COG3852	Histidine kinase
G9457_07215	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
G9457_07230	COG5433	transposase activity
G9457_07245	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
G9457_07260	COG2207	Transcriptional regulator
G9457_07265	COG0538	isocitrate dehydrogenase activity
G9457_07285	COG5433	transposase activity
G9457_07315	COG5433	transposase activity
G9457_07345	COG3383	formate dehydrogenase (NAD+) activity
G9457_07350	COG0437	4 iron, 4 sulfur cluster binding
G9457_07365	COG0281	malic enzyme
G9457_07375	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
G9457_07395	COG0281	malic enzyme
G9457_07400	COG3290	protein histidine kinase activity
G9457_07415	COG0667	Aldo Keto reductase
G9457_07425	COG0697	spore germination
G9457_07445	COG2267	carboxylic ester hydrolase activity
G9457_07450	COG1942	4-Oxalocrotonate Tautomerase
G9457_07460	COG3284	Transcriptional regulator
G9457_07465	COG3706	GGDEF domain
G9457_07470	COG0346	lactoylglutathione lyase activity
G9457_07475	COG0745	RESPONSE REGULATOR receiver
G9457_07480	COG5002	protein histidine kinase activity
G9457_07500	COG1940	carbohydrate kinase activity
G9457_07505	COG3142	Participates in the control of copper homeostasis
G9457_07510	COG0545	Peptidyl-prolyl cis-trans isomerase
G9457_07515	COG1131	(ABC) transporter
G9457_07555	COG0019	diaminopimelate decarboxylase activity
G9457_07560	COG1115	amino acid carrier protein
G9457_07565	COG0095	Lipoate-protein ligase
G9457_07570	COG2233	PERMEase
G9457_07585	COG0534	Mate efflux family protein
G9457_07590	COG2207	Transcriptional regulator
G9457_07595	COG0281	malic enzyme
G9457_07630	COG0733	neurotransmitter:sodium symporter activity
G9457_07635	COG1752	Esterase of the alpha-beta hydrolase superfamily
G9457_07640	COG3706	GGDEF domain
G9457_07645	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
G9457_07650	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
G9457_07660	COG1032	radical SAM domain protein
G9457_07680	COG5433	transposase activity
G9457_07695	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
G9457_07700	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
G9457_07705	COG0739	heme binding
G9457_07705	COG0741	lytic transglycosylase activity
G9457_07705	COG1196	nuclear chromosome segregation
G9457_07710	COG0366	Alpha amylase catalytic
G9457_07730	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
G9457_07740	COG0788	formyltetrahydrofolate deformylase activity
G9457_07745	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
G9457_07755	COG3118	belongs to the thioredoxin family
G9457_07760	COG2091	lysine biosynthetic process via aminoadipic acid
G9457_07765	COG0791	NLP P60 protein
G9457_07770	COG3129	Specifically methylates the adenine in position 1618 of 23S rRNA
G9457_07785	COG1388	LysM domain
G9457_07785	COG1376	ErfK ybiS ycfS ynhG family protein
G9457_07855	COG0469	pyruvate kinase activity
G9457_07885	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
G9457_07905	COG1342	Belongs to the UPF0251 family
G9457_07960	COG1684	flagellar biosynthetic protein fliR
G9457_07970	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
G9457_07995	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
G9457_08005	COG0450	alkyl hydroperoxide reductase
G9457_08025	COG0500	methyltransferase
G9457_08055	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
G9457_08060	COG0217	transcriptional regulatory protein
G9457_08130	COG1846	Transcriptional regulator
G9457_08130	COG1940	carbohydrate kinase activity
G9457_08135	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
G9457_08140	COG0363	glucosamine-6-phosphate deaminase activity
G9457_08165	COG0735	belongs to the Fur family
G9457_08175	COG0716	FMN binding
G9457_08190	COG0596	Alpha beta hydrolase
G9457_08195	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
G9457_08200	COG0033	Phosphoglucomutase
G9457_08210	COG1846	Transcriptional regulator
G9457_08215	COG2951	lytic endotransglycosylase activity
G9457_08220	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
G9457_08225	COG4136	ATPase activity
G9457_08230	COG4135	transport system, permease component
G9457_08235	COG4134	Bacterial extracellular solute-binding protein
G9457_08240	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
G9457_08245	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
G9457_08255	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
G9457_08260	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
G9457_08275	COG0729	surface antigen
G9457_08280	COG2911	Protein conserved in bacteria
G9457_08295	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
G9457_08320	COG1607	acyl-coa hydrolase
G9457_08340	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
G9457_08345	COG2226	methyltransferase
G9457_08350	COG0328	RNA-DNA hybrid ribonuclease activity
G9457_08370	COG0784	Response regulator, receiver
G9457_08370	COG3437	response regulator, receiver
G9457_08375	COG1960	acyl-CoA dehydrogenase activity
G9457_08380	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
G9457_08385	COG0121	glutamine amidotransferase
G9457_08415	COG2197	response regulator
G9457_08420	COG3850	Histidine kinase
G9457_08425	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
G9457_08430	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
G9457_08440	COG0243	molybdopterin cofactor binding
G9457_08445	COG0437	4 iron, 4 sulfur cluster binding
G9457_08450	COG0348	domain, Protein
G9457_08460	COG3005	denitrification pathway
G9457_08465	COG0521	Mo-molybdopterin cofactor biosynthetic process
G9457_08470	COG0315	cyclic pyranopterin monophosphate synthase activity
G9457_08475	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
G9457_08480	COG0314	molybdopterin synthase activity
G9457_08495	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
G9457_08500	COG0596	Alpha beta hydrolase
G9457_08525	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
G9457_08535	COG0302	gtp cyclohydrolase
G9457_08540	COG0840	transmembrane signaling receptor activity
G9457_08545	COG2759	Belongs to the formate--tetrahydrofolate ligase family
G9457_08555	COG0583	DNA-binding transcription factor activity
G9457_08560	COG2353	YceI-like domain
G9457_08585	COG2195	Cleaves the N-terminal amino acid of tripeptides
G9457_08595	COG1166	arginine decarboxylase activity
G9457_08610	COG0346	lactoylglutathione lyase activity
G9457_08620	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
G9457_08625	COG1187	pseudouridine synthase activity
G9457_08630	COG2807	transmembrane transport
G9457_08670	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
G9457_08700	COG2814	Major facilitator Superfamily
G9457_08705	COG0656	L-ascorbic acid biosynthetic process
G9457_08710	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
G9457_08740	COG0583	DNA-binding transcription factor activity
G9457_08745	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
G9457_08750	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
G9457_08755	COG2271	Major facilitator Superfamily
G9457_08760	COG1349	DNA-binding transcription factor activity
G9457_08770	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
G9457_08775	COG0584	glycerophosphoryl diester phosphodiesterase
G9457_08780	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
G9457_08785	COG1605	Chorismate mutase
G9457_08785	COG0287	Prephenate dehydrogenase
G9457_08790	COG0583	DNA-binding transcription factor activity
G9457_08795	COG3085	chromosome segregation
G9457_08800	COG4574	serine-type endopeptidase inhibitor activity
G9457_08820	COG1770	oligopeptidase
G9457_08840	COG3083	sulfuric ester hydrolase activity
G9457_08845	COG3082	Protein of unknown function (DUF1414)
G9457_08850	COG3081	Nucleoid-associated protein
G9457_08855	COG2182	Extracellular solute-binding protein
G9457_08860	COG1175	transmembrane transport
G9457_08865	COG3833	ABC-type maltose transport systems, permease component
G9457_08870	COG3842	ATPase activity
G9457_08885	COG0628	permease
G9457_08890	COG0425	Belongs to the sulfur carrier protein TusA family
G9457_08895	COG4783	chaperone-mediated protein folding
G9457_08905	COG1393	Belongs to the ArsC family
G9457_08915	COG3124	Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP
G9457_08920	COG2431	L-lysine efflux transmembrane transporter activity
G9457_08955	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
G9457_08965	COG0446	pyridine nucleotide-disulphide oxidoreductase
G9457_08970	COG2373	Large extracellular alpha-helical protein
G9457_08975	COG4953	penicillin-binding protein 1C
G9457_08985	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
G9457_08985	COG0301	tRNA thio-modification
G9457_09000	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
G9457_09030	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
G9457_09040	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
G9457_09060	COG0483	inositol monophosphate 1-phosphatase activity
G9457_09070	COG0625	glutathione transferase activity
G9457_09080	COG0601	transmembrane transport
G9457_09085	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
G9457_09090	COG0444	Belongs to the ABC transporter superfamily
G9457_09095	COG2814	Major facilitator Superfamily
G9457_09100	COG0583	DNA-binding transcription factor activity
G9457_09105	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
G9457_09110	COG0243	molybdopterin cofactor binding
G9457_09130	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
G9457_09135	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
G9457_09140	COG0404	The glycine cleavage system catalyzes the degradation of glycine
G9457_09145	COG0509	glycine decarboxylation via glycine cleavage system
G9457_09185	COG0517	IMP dehydrogenase activity
G9457_09195	COG0343	queuine tRNA-ribosyltransferase activity
G9457_09200	COG1862	Preprotein translocase
G9457_09215	COG2897	thiosulfate sulfurtransferase activity
G9457_09230	COG0826	peptidase U32
G9457_09235	COG3154	lipid carrier protein
G9457_09250	COG1959	2 iron, 2 sulfur cluster binding
G9457_09255	COG1104	cysteine desulfurase activity
G9457_09260	COG0822	iron-sulfur transferase activity
G9457_09270	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
G9457_09275	COG0443	Heat shock 70 kDa protein
G9457_09280	COG0633	Ferredoxin
G9457_09290	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
G9457_09295	COG0105	UTP biosynthetic process
G9457_09300	COG0820	rRNA (adenine-C2-)-methyltransferase activity
G9457_09310	COG1426	Protein conserved in bacteria
G9457_09315	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
G9457_09320	COG0124	histidyl-tRNA synthetase
G9457_09325	COG2976	Protein conserved in bacteria
G9457_09330	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
G9457_09335	COG1160	GTP binding
G9457_09340	COG1645	bacterial-type flagellum-dependent swarming motility
G9457_09345	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
G9457_09350	COG0047	phosphoribosylformylglycinamidine synthase activity
G9457_09350	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
G9457_09360	COG2354	Protein conserved in bacteria
G9457_09375	COG5433	transposase activity
G9457_09400	COG1242	4 iron, 4 sulfur cluster binding
G9457_09480	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
G9457_09485	COG1288	antiporter activity
G9457_09490	COG0436	Aminotransferase
G9457_09500	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
G9457_09505	COG2027	D-alanyl-D-alanine carboxypeptidase
G9457_09510	COG1061	Type III restriction enzyme res subunit
G9457_09515	COG1566	PFAM secretion protein HlyD family protein
G9457_09525	COG1966	Carbon starvation protein
G9457_09530	COG3279	Response regulator of the LytR AlgR family
G9457_09535	COG3275	phosphorelay sensor kinase activity
G9457_09555	COG1454	alcohol dehydrogenase
G9457_09555	COG1012	belongs to the aldehyde dehydrogenase family
G9457_09565	COG2095	MarC family integral membrane protein
G9457_09575	COG0601	transmembrane transport
G9457_09580	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
G9457_09585	COG0444	Belongs to the ABC transporter superfamily
G9457_09600	COG0861	Integral membrane protein TerC family
G9457_09605	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
G9457_09615	COG1301	dicarboxylic acid transport
G9457_09630	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
G9457_09645	COG0537	adenosine 5'-monophosphoramidase activity
G9457_09680	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
G9457_09685	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
G9457_09705	COG5433	transposase activity
G9457_09720	COG1007	ATP synthesis coupled electron transport
G9457_09725	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
G9457_09755	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
G9457_09760	COG1034	ATP synthesis coupled electron transport
G9457_09775	COG0649	NAD binding
G9457_09775	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
G9457_09780	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
G9457_09785	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
G9457_09790	COG1360	Flagellar Motor Protein
G9457_09810	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
G9457_09825	COG4597	amino acid ABC transporter
G9457_09830	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
G9457_09835	COG0765	amino acid transport
G9457_09840	COG1126	abc transporter atp-binding protein
G9457_09850	COG0724	RNA recognition motif
G9457_09855	COG4989	oxidoreductase activity
G9457_09885	COG0583	DNA-binding transcription factor activity
G9457_09900	COG5001	Diguanylate cyclase
G9457_09900	COG3300	MHYT domain
G9457_09920	COG2814	Major facilitator Superfamily
G9457_09935	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
G9457_09940	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
G9457_09945	COG0539	negative regulation of cytoplasmic translation
G9457_09950	COG0776	regulation of translation
G9457_09960	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
G9457_09965	COG0284	orotidine-5'-phosphate decarboxylase activity
G9457_09980	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
G9457_09985	COG0602	queuosine metabolic process
G9457_09990	COG3530	Putative quorum-sensing-regulated virulence factor
G9457_09995	COG2096	Adenosyltransferase
G9457_10000	COG2916	Histone family protein nucleoid-structuring protein H-NS
G9457_10015	COG1757	Na H antiporter
G9457_10020	COG1435	thymidine kinase activity
G9457_10040	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
G9457_10055	COG5433	transposase activity
G9457_10065	COG0437	4 iron, 4 sulfur cluster binding
G9457_10070	COG5557	Pfam Polysulphide reductase, NrfD
G9457_10075	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
G9457_10080	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
G9457_10085	COG1773	rubredoxin
G9457_10095	COG0601	transmembrane transport
G9457_10100	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
G9457_10115	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
G9457_10120	COG0375	protein maturation
G9457_10125	COG0309	Hydrogenase expression formation protein (HypE)
G9457_10135	COG0298	carbon dioxide binding
G9457_10140	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
G9457_10150	COG1921	L-seryl-tRNASec selenium transferase activity
G9457_10160	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
G9457_10170	COG3260	NADH ubiquinone oxidoreductase 20
G9457_10175	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
G9457_10180	COG3261	NADH dehydrogenase
G9457_10180	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
G9457_10185	COG0650	Formate hydrogenlyase subunit 4
G9457_10190	COG0651	ATP synthesis coupled electron transport
G9457_10195	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
G9457_10200	COG3158	transport of potassium into the cell
G9457_10250	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
G9457_10255	COG0326	Molecular chaperone. Has ATPase activity
G9457_10265	COG0563	adenylate kinase activity
G9457_10270	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
G9457_10275	COG3788	relative of glutathione S-transferase, MAPEG superfamily
G9457_10280	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
G9457_10285	COG0840	transmembrane signaling receptor activity
G9457_10340	COG1021	2,3-dihydroxybenzoate-AMP ligase
G9457_10345	COG1535	isochorismatase
G9457_10345	COG3433	isochorismatase activity
G9457_10350	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
G9457_10355	COG1028	Short-chain dehydrogenase reductase Sdr
G9457_10365	COG3321	synthase
G9457_10365	COG1028	Short-chain dehydrogenase reductase Sdr
G9457_10365	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
G9457_10365	COG0318	PFAM AMP-dependent synthetase and ligase
G9457_10365	COG0300	oxidoreductase activity
G9457_10370	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
G9457_10375	COG2977	Belongs to the P-Pant transferase superfamily
G9457_10380	COG1120	ATPase activity
G9457_10385	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
G9457_10390	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
G9457_10395	COG4771	TonB-dependent receptor
G9457_10420	COG0644	oxidoreductase
G9457_10420	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
G9457_10440	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
G9457_10445	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
G9457_10450	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
G9457_10465	COG1570	exodeoxyribonuclease VII activity
G9457_10485	COG5433	transposase activity
G9457_10510	COG0516	GMP reductase activity
G9457_10510	COG0517	IMP dehydrogenase activity
G9457_10515	COG0518	GMP synthase (glutamine-hydrolyzing) activity
G9457_10515	COG0519	Catalyzes the synthesis of GMP from XMP
G9457_10575	COG2062	phosphohistidine phosphatase, SixA
G9457_10585	COG0697	spore germination
G9457_10590	COG4166	transmembrane transport
G9457_10595	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
G9457_10600	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
G9457_10610	COG4591	ABC-type transport system involved in lipoprotein release permease component
G9457_10615	COG1136	(ABC) transporter
G9457_10620	COG4591	ABC-type transport system involved in lipoprotein release permease component
G9457_10625	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
G9457_10635	COG0544	peptidyl-prolyl cis-trans isomerase activity
G9457_10640	COG0740	serine-type endopeptidase activity
G9457_10645	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
G9457_10650	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
G9457_10655	COG0776	regulation of translation
G9457_10660	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
G9457_10665	COG0488	(ABC) transporter
G9457_10670	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
G9457_10675	COG3162	membrane
G9457_10690	COG1024	Enoyl-CoA hydratase
G9457_10690	COG1250	3-hydroxyacyl-CoA dehydrogenase
G9457_10705	COG0456	acetyltransferase
G9457_10715	COG1584	GPR1 FUN34 yaaH family protein
G9457_10745	COG1024	Enoyl-CoA hydratase
G9457_10750	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
G9457_10775	COG1960	acyl-CoA dehydrogenase activity
G9457_10780	COG1024	Enoyl-CoA hydratase
G9457_10785	COG1024	Enoyl-CoA hydratase
G9457_10795	COG1028	Short-chain dehydrogenase reductase Sdr
G9457_10805	COG0730	response to heat
G9457_10835	COG2378	regulation of single-species biofilm formation
G9457_10845	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
G9457_10845	COG0140	phosphoribosyl-ATP diphosphatase activity
G9457_10850	COG0107	imidazoleglycerol-phosphate synthase activity
G9457_10855	COG2205	protein histidine kinase activity
G9457_10855	COG2198	Histidine kinase
G9457_10855	COG0784	Response regulator, receiver
G9457_10860	COG2199	diguanylate cyclase activity
G9457_10865	COG3437	response regulator, receiver
G9457_10870	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
G9457_10875	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
G9457_10880	COG0131	Imidazoleglycerol-phosphate dehydratase
G9457_10880	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
G9457_10885	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
G9457_10890	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
G9457_10895	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
G9457_10905	COG1199	ATP-dependent helicase activity
G9457_10910	COG1214	PFAM Peptidase M22, glycoprotease
G9457_10920	COG2267	carboxylic ester hydrolase activity
G9457_10925	COG0318	PFAM AMP-dependent synthetase and ligase
G9457_10945	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
G9457_10950	COG2832	Protein of unknown function (DUF454)
G9457_10955	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
G9457_10960	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
G9457_10965	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
G9457_10970	COG3314	Sporulation integral membrane protein YlbJ
G9457_10975	COG2197	response regulator
G9457_10980	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
G9457_10980	COG0617	tRNA 3'-terminal CCA addition
G9457_10980	COG0517	IMP dehydrogenase activity
G9457_10985	COG1643	Atp-dependent helicase
G9457_10995	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
G9457_11000	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
G9457_11005	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
G9457_11010	COG0709	Synthesizes selenophosphate from selenide and ATP
G9457_11025	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
G9457_11035	COG1254	Belongs to the acylphosphatase family
G9457_11040	COG0625	glutathione transferase activity
G9457_11045	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
G9457_11045	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
G9457_11050	COG0489	protein tyrosine kinase activity
G9457_11055	COG0572	uridine kinase
G9457_11060	COG0717	Belongs to the dCTP deaminase family
G9457_11065	COG0306	phosphate transporter
G9457_11070	COG1530	ribonuclease E activity
G9457_11080	COG0546	phosphoglycolate phosphatase activity
G9457_11090	COG1399	metal-binding, possibly nucleic acid-binding protein
G9457_11095	COG0333	Belongs to the bacterial ribosomal protein bL32 family
G9457_11100	COG0416	fatty acid biosynthetic process
G9457_11105	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
G9457_11115	COG1028	Short-chain dehydrogenase reductase Sdr
G9457_11120	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
G9457_11125	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
G9457_11130	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
G9457_11135	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
G9457_11140	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
G9457_11145	COG0470	DNA polymerase III
G9457_11150	COG0084	hydrolase, TatD family'
G9457_11165	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
G9457_11165	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
G9457_11175	COG2995	paraquat-inducible protein a
G9457_11185	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
G9457_11190	COG0372	Belongs to the citrate synthase family
G9457_11240	COG4221	oxidoreductase activity
G9457_11270	COG3620	sequence-specific DNA binding
G9457_11345	COG1067	ATP-dependent peptidase activity
G9457_11350	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
G9457_11365	COG0488	(ABC) transporter
G9457_11375	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
G9457_11375	COG0116	Belongs to the methyltransferase superfamily
G9457_11390	COG0167	dihydroorotate dehydrogenase activity
G9457_11400	COG5433	transposase activity
G9457_11430	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
G9457_11435	COG1956	GAF domain-containing protein
G9457_11445	COG3278	Belongs to the heme-copper respiratory oxidase family
G9457_11460	COG2010	Cytochrome c
G9457_11470	COG2217	Heavy metal translocating P-type atpase
G9457_11485	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
G9457_11490	COG0589	response to stress
G9457_11495	COG0037	tRNA processing
G9457_11515	COG1869	D-ribose catabolic process
G9457_11525	COG1172	Belongs to the binding-protein-dependent transport system permease family
G9457_11530	COG1879	ABC-type sugar transport system periplasmic component
G9457_11535	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
G9457_11540	COG1609	Transcriptional regulator
G9457_11585	COG0776	regulation of translation
G9457_11590	COG0072	phenylalanine-tRNA ligase activity
G9457_11590	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
G9457_11595	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
G9457_11600	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
G9457_11605	COG0291	Belongs to the bacterial ribosomal protein bL35 family
G9457_11610	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
G9457_11615	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
G9457_11640	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
G9457_11650	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
G9457_11655	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
G9457_11660	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
G9457_11665	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
G9457_11670	COG3313	Fe-S protein
G9457_11675	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
G9457_11675	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
G9457_11675	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
G9457_11680	COG1105	Belongs to the carbohydrate kinase PfkB family
G9457_11685	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
G9457_11685	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
G9457_11690	COG1609	Transcriptional regulator
G9457_11695	COG0814	amino acid
G9457_11705	COG5654	RES domain protein
G9457_11710	COG0513	Belongs to the DEAD box helicase family
G9457_11720	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
G9457_11725	COG2890	protein-(glutamine-N5) methyltransferase activity
G9457_11730	COG2840	Smr protein MutS2
G9457_11735	COG3706	GGDEF domain
G9457_11785	COG2824	Alkylphosphonate utilization operon protein PhnA
G9457_11790	COG1024	Enoyl-CoA hydratase
G9457_11790	COG1250	3-hydroxyacyl-CoA dehydrogenase
G9457_11795	COG0183	Belongs to the thiolase family
G9457_11800	COG0714	Associated with various cellular activities
G9457_11840	COG2067	long-chain fatty acid transport protein
G9457_11845	COG2067	long-chain fatty acid transport protein
G9457_11850	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
G9457_11870	COG3123	guanosine phosphorylase activity
G9457_11875	COG1760	l-serine dehydratase
G9457_11880	COG1760	l-serine dehydratase
G9457_11885	COG2951	lytic endotransglycosylase activity
G9457_11890	COG3100	YcgL domain-containing protein
G9457_11895	COG0850	regulation of cytokinetic process
G9457_11900	COG2894	cell division
G9457_11905	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
G9457_11910	COG3099	Belongs to the UPF0263 family
G9457_11915	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
G9457_11960	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
G9457_11965	COG0697	spore germination
G9457_11970	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
G9457_11975	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
G9457_11985	COG0307	riboflavin synthase, alpha
G9457_11995	COG0534	Mate efflux family protein
G9457_12030	COG0417	DNA replication proofreading
G9457_12060	COG1560	Kdo2-lipid A biosynthetic process
G9457_12070	COG0583	DNA-binding transcription factor activity
G9457_12075	COG0673	inositol 2-dehydrogenase activity
G9457_12080	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
G9457_12085	COG0583	DNA-binding transcription factor activity
G9457_12095	COG2723	6-phospho-beta-galactosidase activity
G9457_12100	COG0583	DNA-binding transcription factor activity
G9457_12130	COG3134	Outer membrane lipoprotein
G9457_12150	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
G9457_12170	COG4681	YaeQ
G9457_12210	COG0242	peptide deformylase activity
G9457_12240	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
G9457_12245	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
G9457_12250	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
G9457_12260	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
G9457_12270	COG1434	Gram-negative-bacterium-type cell wall biogenesis
G9457_12280	COG0205	6-phosphofructokinase activity
G9457_12320	COG1011	Hydrolase
G9457_12375	COG3593	DNA synthesis involved in DNA repair
G9457_12390	COG0583	DNA-binding transcription factor activity
G9457_12395	COG0730	response to heat
G9457_12400	COG3148	PFAM DTW domain containing protein
G9457_12410	COG1181	Belongs to the D-alanine--D-alanine ligase family
G9457_12420	COG0386	Belongs to the glutathione peroxidase family
G9457_12425	COG0513	Belongs to the DEAD box helicase family
G9457_12440	COG1742	UPF0060 membrane protein
G9457_12480	COG2329	Antibiotic biosynthesis monooxygenase
G9457_12485	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
G9457_12505	COG3243	poly(R)-hydroxyalkanoic acid synthase
G9457_12515	COG2501	S4 domain
G9457_12525	COG1132	(ABC) transporter
G9457_12540	COG3118	belongs to the thioredoxin family
G9457_12545	COG0471	metal ion transport
G9457_12550	COG0058	SHG alpha-glucan phosphorylase activity
G9457_12600	COG5433	transposase activity
G9457_12625	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
G9457_12635	COG0814	amino acid
G9457_12640	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
G9457_12645	COG0514	ATP-dependent DNA helicase (RecQ)
G9457_12650	COG2766	serine protein kinase
G9457_12660	COG2719	SpoVR family
G9457_12665	COG2186	Transcriptional regulator
G9457_12670	COG3067	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
G9457_12675	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
G9457_12680	COG0586	Pfam SNARE associated Golgi protein
G9457_12690	COG0556	nucleotide-excision repair
G9457_12700	COG0569	domain protein
G9457_12700	COG2985	domain, Protein
G9457_12705	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
G9457_12710	COG5433	transposase activity
G9457_12740	COG4565	transcriptional regulatory protein
G9457_12745	COG3290	protein histidine kinase activity
G9457_12750	COG1940	carbohydrate kinase activity
G9457_12750	COG1846	Transcriptional regulator
G9457_12755	COG0840	transmembrane signaling receptor activity
G9457_12760	COG3012	SEC-C Motif Domain Protein
G9457_12765	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
G9457_12770	COG3075	Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses fumarate or nitrate as electron acceptor
G9457_12790	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
G9457_12795	COG0437	4 iron, 4 sulfur cluster binding
G9457_12800	COG3301	Polysulphide reductase, NrfD
G9457_12815	COG3088	subunit of a heme lyase
G9457_12815	COG4235	cytochrome complex assembly
G9457_12830	COG3033	Beta-eliminating lyase
G9457_12840	COG3046	protein related to deoxyribodipyrimidine photolyase
G9457_12885	COG4774	siderophore transport
G9457_12890	COG2207	Transcriptional regulator
G9457_12890	COG3708	Transcriptional regulator
G9457_12900	COG0583	DNA-binding transcription factor activity
G9457_12905	COG2910	NAD(P)H-binding
G9457_12925	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
G9457_12930	COG1944	ATP diphosphatase activity
G9457_12935	COG2116	formate transmembrane transporter activity
G9457_12940	COG1882	Formate acetyltransferase
G9457_12945	COG2983	Belongs to the UPF0260 family
G9457_12950	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
G9457_12955	COG0045	succinate-CoA ligase (ADP-forming) activity
G9457_12960	COG0508	dehydrogenase complex catalyzes the overall conversion of
G9457_12965	COG0567	Dehydrogenase, E1 component
G9457_12975	COG1053	succinate dehydrogenase
G9457_12980	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
G9457_13005	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
G9457_13010	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
G9457_13010	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
G9457_13020	COG3069	C4-dicarboxylate transmembrane transporter activity
G9457_13035	COG1451	nucleotide metabolic process
G9457_13050	COG0254	rRNA binding
G9457_13055	COG0257	Belongs to the bacterial ribosomal protein bL36 family
G9457_13075	COG3867	Arabinogalactan endo-beta-1,4-galactanase
G9457_13080	COG3833	ABC-type maltose transport systems, permease component
G9457_13130	COG3867	Arabinogalactan endo-beta-1,4-galactanase
G9457_13145	COG4580	involved in the transport of maltose and maltodextrins
G9457_13150	COG1609	Transcriptional regulator
G9457_13155	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
G9457_13175	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
G9457_13185	COG1172	Belongs to the binding-protein-dependent transport system permease family
G9457_13190	COG1129	ABC transporter
G9457_13195	COG1879	ABC-type sugar transport system periplasmic component
G9457_13200	COG1069	ribulokinase activity
G9457_13210	COG2160	L-arabinose isomerase activity
G9457_13215	COG0583	DNA-binding transcription factor activity
G9457_13220	COG0436	Aminotransferase
G9457_13225	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
G9457_13240	COG2925	Exonuclease
G9457_13250	COG3345	alpha-galactosidase
G9457_13260	COG1380	Effector of murein hydrolase LrgA
G9457_13265	COG1346	cytolysis
G9457_13270	COG0295	cytidine deaminase activity
G9457_13275	COG1022	Amp-dependent synthetase and ligase
G9457_13290	COG0861	Integral membrane protein TerC family
G9457_13300	COG2199	diguanylate cyclase activity
G9457_13315	COG2154	pterin-4-alpha-carbinolamine dehydratase
G9457_13325	COG3768	UPF0283 membrane protein
G9457_13330	COG3106	COG3106 Predicted ATPase
G9457_13345	COG1842	Phage shock protein A
G9457_13360	COG4168	peptide transport system, permease
G9457_13365	COG4171	peptide transport system, permease
G9457_13370	COG4172	Belongs to the ABC transporter superfamily
G9457_13375	COG4172	Belongs to the ABC transporter superfamily
G9457_13385	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
G9457_13390	COG1286	toxin biosynthetic process
G9457_13395	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
G9457_13400	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
G9457_13405	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
G9457_13410	COG0531	amino acid
G9457_13410	COG1674	ftsk spoiiie
G9457_13430	COG0492	ferredoxin-NADP+ reductase activity
G9457_13440	COG3134	Outer membrane lipoprotein
G9457_13445	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
G9457_13450	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
G9457_13455	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
G9457_13460	COG0542	response to heat
G9457_13465	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
G9457_13470	COG1278	Cold shock
G9457_13475	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
G9457_13540	COG3829	transcription factor binding
G9457_13610	COG0659	secondary active sulfate transmembrane transporter activity
G9457_13670	COG4657	Part of a membrane complex involved in electron transport
G9457_13675	COG2878	Part of a membrane complex involved in electron transport
G9457_13685	COG4658	electron transport chain
G9457_13690	COG4659	FMN binding
G9457_13695	COG4660	Part of a membrane complex involved in electron transport
G9457_13700	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
G9457_13705	COG0346	lactoylglutathione lyase activity
G9457_13720	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
G9457_13725	COG2056	Na+-H+ antiporter family
G9457_13730	COG5001	Diguanylate cyclase
G9457_13730	COG3300	MHYT domain
G9457_13740	COG0513	Belongs to the DEAD box helicase family
G9457_13745	COG2050	protein possibly involved in aromatic compounds catabolism
G9457_13755	COG0247	lactate metabolic process
G9457_13755	COG0277	FAD linked oxidase domain protein
G9457_13765	COG1253	flavin adenine dinucleotide binding
G9457_13770	COG1902	pentaerythritol trinitrate reductase activity
G9457_13780	COG0647	UMP catabolic process
G9457_13785	COG4651	solute:proton antiporter activity
G9457_13785	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
G9457_13795	COG0367	asparagine synthase
G9457_13825	COG0625	glutathione transferase activity
G9457_13830	COG0625	glutathione transferase activity
G9457_13855	COG0564	pseudouridine synthase activity
G9457_13875	COG0840	transmembrane signaling receptor activity
G9457_13885	COG0670	Belongs to the BI1 family
G9457_13890	COG1289	transmembrane transporter activity
G9457_13895	COG2920	part of a sulfur-relay system
G9457_13900	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
G9457_13905	COG0285	dihydrofolate synthase activity
G9457_13910	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
G9457_13915	COG0101	tRNA pseudouridine synthase activity
G9457_13925	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
G9457_13930	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
G9457_13935	COG0671	phosphoesterase, PA-phosphatase related
G9457_14015	COG0672	)-iron permease
G9457_14040	COG2814	Major facilitator Superfamily
G9457_14055	COG1136	(ABC) transporter
G9457_14060	COG0577	efflux transmembrane transporter activity
G9457_14075	COG1285	pathogenesis
G9457_14140	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
G9457_14145	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
G9457_14145	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
G9457_14150	COG0527	aspartate kinase activity
G9457_14160	COG1368	sulfuric ester hydrolase activity
G9457_14165	COG1619	proteins homologs of microcin C7 resistance protein MccF
G9457_14175	COG0393	Putative heavy-metal-binding
G9457_14180	COG1252	NADH dehydrogenase
G9457_14215	COG0789	Transcriptional regulator
G9457_14230	COG0493	'glutamate synthase
G9457_14235	COG0067	glutamate synthase
G9457_14235	COG0069	glutamate synthase activity
G9457_14235	COG0070	glutamate synthase
G9457_14285	COG0513	Belongs to the DEAD box helicase family
G9457_14290	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
G9457_14320	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
G9457_14325	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
G9457_14330	COG0505	Belongs to the CarA family
G9457_14335	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
G9457_14360	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
G9457_14365	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
G9457_14370	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
G9457_14375	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
G9457_14380	COG4138	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system
G9457_14390	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
G9457_14390	COG2205	protein histidine kinase activity
G9457_14435	COG2119	membrane
G9457_14465	COG2203	Gaf domain
G9457_14465	COG2199	diguanylate cyclase activity
G9457_14500	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
G9457_14510	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
G9457_14515	COG2261	transglycosylase associated protein
G9457_14555	COG0322	excinuclease ABC activity
G9457_14560	COG2197	response regulator
G9457_14565	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
G9457_14570	COG2835	tetraacyldisaccharide 4'-kinase activity
G9457_14575	COG1663	tetraacyldisaccharide 4'-kinase activity
G9457_14580	COG1132	(ABC) transporter
G9457_14585	COG0658	competence protein
G9457_14585	COG2333	competence protein COMEC
G9457_14600	COG0433	COG0433 Predicted ATPase
G9457_14605	COG1448	Aminotransferase
G9457_14620	COG1199	ATP-dependent helicase activity
G9457_14635	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
G9457_14640	COG1785	Belongs to the alkaline phosphatase family
G9457_14660	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
G9457_14675	COG2271	Major facilitator Superfamily
G9457_14680	COG3706	GGDEF domain
G9457_14685	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
G9457_14690	COG0765	amino acid transport
G9457_14695	COG1126	abc transporter atp-binding protein
G9457_14705	COG0531	amino acid
G9457_14720	COG1253	flavin adenine dinucleotide binding
G9457_14725	COG0704	Plays a role in the regulation of phosphate uptake
G9457_14730	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
G9457_14735	COG0581	inorganic phosphate transmembrane transporter activity
G9457_14740	COG0573	inorganic phosphate transmembrane transporter activity
G9457_14745	COG0590	tRNA wobble adenosine to inosine editing
G9457_14755	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
G9457_14775	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
G9457_14780	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
G9457_14785	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
G9457_14790	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
G9457_14825	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
G9457_14830	COG0248	Ppx GppA phosphatase
G9457_14835	COG2239	Acts as a magnesium transporter
G9457_14870	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
G9457_14880	COG4787	bacterial-type flagellum-dependent cell motility
G9457_14900	COG1815	bacterial-type flagellum-dependent cell motility
G9457_14905	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
G9457_14910	COG0784	Response regulator, receiver
G9457_14910	COG0835	chemotaxis
G9457_14930	COG0622	Phosphoesterase
G9457_14935	COG4166	transmembrane transport
G9457_14960	COG0697	spore germination
G9457_15000	COG1278	Cold shock
G9457_15060	COG3132	Protein of unknown function, DUF480
G9457_15115	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
G9457_15130	COG5433	transposase activity
G9457_15140	COG0471	metal ion transport
G9457_15140	COG3273	potassium ion transport
G9457_15145	COG5433	transposase activity
G9457_15175	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
G9457_15180	COG0438	transferase activity, transferring glycosyl groups
G9457_15200	COG1450	Type ii and iii secretion system protein
G9457_15240	COG1459	type II secretion system
G9457_15245	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
G9457_15265	COG1091	dTDP-4-dehydrorhamnose reductase activity
G9457_15285	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
G9457_15290	COG1309	transcriptional regulator
G9457_15305	COG1946	Acyl-CoA thioesterase
G9457_15315	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
G9457_15325	COG0009	L-threonylcarbamoyladenylate synthase
G9457_15335	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
G9457_15340	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
G9457_15340	COG0512	Glutamine amidotransferase of anthranilate synthase
G9457_15345	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
G9457_15350	COG0134	indole-3-glycerol-phosphate synthase activity
G9457_15350	COG0135	phosphoribosylanthranilate isomerase activity
G9457_15355	COG0133	tryptophan synthase activity
G9457_15360	COG0159	tryptophan synthase activity
G9457_15410	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
G9457_15410	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
G9457_15410	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
G9457_15420	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
G9457_15440	COG0482	sulfurtransferase activity
G9457_15445	COG2915	High frequency lysogenization protein hflD homolog
G9457_15450	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
G9457_15455	COG2850	peptidyl-arginine hydroxylation
G9457_15510	COG0259	pyridoxamine-phosphate oxidase activity
G9457_15525	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
G9457_15525	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
G9457_15530	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
G9457_15550	COG3088	subunit of a heme lyase
G9457_15550	COG4235	cytochrome complex assembly
G9457_15555	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
G9457_15560	COG1138	Cytochrome C-type biogenesis protein
G9457_15565	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
G9457_15570	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
G9457_15575	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
G9457_15580	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
G9457_15600	COG0835	chemotaxis
G9457_15610	COG1192	Involved in chromosome partitioning
G9457_15615	COG1360	Flagellar Motor Protein
G9457_15620	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
G9457_15625	COG2201	protein-glutamate methylesterase activity
G9457_15630	COG0784	Response regulator, receiver
G9457_15630	COG2198	Histidine kinase
G9457_15630	COG0643	Histidine kinase
G9457_15640	COG0583	DNA-binding transcription factor activity
G9457_15650	COG0791	NLP P60 protein
G9457_15665	COG1309	transcriptional regulator
G9457_15705	COG0534	Mate efflux family protein
G9457_15715	COG2841	Protein conserved in bacteria
G9457_15720	COG1013	pyruvate-flavodoxin oxidoreductase activity
G9457_15720	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
G9457_15720	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
G9457_15720	COG0674	pyruvate-flavodoxin oxidoreductase activity
G9457_15735	COG0633	Ferredoxin
G9457_15735	COG3217	Mosc domain protein beta barrel domain protein
G9457_15735	COG0633	Ferredoxin
G9457_15735	COG3217	Mosc domain protein beta barrel domain protein
G9457_15745	COG0501	Belongs to the peptidase M48B family
G9457_15750	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
G9457_15755	COG2226	methyltransferase
G9457_15755	COG1073	alpha beta
G9457_15760	COG0156	8-amino-7-oxononanoate synthase activity
G9457_15765	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
G9457_15785	COG0017	Asparaginyl-tRNA synthetase
G9457_15805	COG0583	DNA-binding transcription factor activity
G9457_15810	COG1393	Belongs to the ArsC family
G9457_15815	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
G9457_15820	COG1876	peptidase activity
G9457_15830	COG3263	regulation of cellular component size
G9457_15850	COG5433	transposase activity
G9457_15860	COG1280	lysine exporter protein (LysE YggA)
G9457_15865	COG0840	transmembrane signaling receptor activity
G9457_15885	COG1957	nucleoside hydrolase
G9457_15900	COG1454	alcohol dehydrogenase
G9457_15940	COG2894	cell division
G9457_15950	COG4964	Belongs to the GSP D family
G9457_15980	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
G9457_15985	COG0702	epimerase
G9457_15990	COG2914	Belongs to the UPF0125 (RnfH) family
G9457_15995	COG2867	negative regulation of translational initiation
G9457_16005	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
G9457_16015	COG0582	viral genome integration into host DNA
G9457_16060	COG0538	isocitrate dehydrogenase activity
G9457_16065	COG2207	Transcriptional regulator
G9457_16095	COG5433	transposase activity
G9457_16115	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
G9457_16115	COG1263	PTS System
G9457_16120	COG1609	Transcriptional regulator
G9457_16155	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
G9457_16160	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
G9457_16165	COG1845	cytochrome c oxidase, subunit III
G9457_16170	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
G9457_16175	COG0109	protoheme IX farnesyltransferase activity
G9457_16235	COG0708	Exodeoxyribonuclease III
G9457_16275	COG0095	Lipoate-protein ligase
G9457_16325	COG1285	pathogenesis
G9457_16355	COG0484	heat shock protein binding
G9457_16360	COG0443	Heat shock 70 kDa protein
G9457_16365	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
G9457_16370	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
G9457_16375	COG0497	DNA recombination
G9457_16380	COG1227	inorganic diphosphatase activity
G9457_16390	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
G9457_16395	COG0577	efflux transmembrane transporter activity
G9457_16395	COG1136	(ABC) transporter
G9457_16400	COG1538	Outer membrane efflux protein
G9457_16405	COG2375	cellular response to nickel ion
G9457_16410	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
G9457_16425	COG2916	Histone family protein nucleoid-structuring protein H-NS
G9457_16450	COG2201	protein-glutamate methylesterase activity
G9457_16455	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
G9457_16500	COG2199	diguanylate cyclase activity
G9457_16500	COG2200	EAL domain
G9457_16500	COG2203	Gaf domain
G9457_16505	COG0826	peptidase U32
G9457_16510	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
G9457_16515	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
G9457_16530	COG2200	EAL domain
G9457_16535	COG0737	Belongs to the 5'-nucleotidase family
G9457_16555	COG2204	response regulator
G9457_16560	COG0545	Peptidyl-prolyl cis-trans isomerase
G9457_16575	COG1047	Peptidyl-prolyl cis-trans
G9457_16580	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
G9457_16590	COG0835	chemotaxis
G9457_16590	COG0784	Response regulator, receiver
G9457_16595	COG0429	hydrolase of the alpha beta-hydrolase fold
G9457_16600	COG4251	negative regulation of phosphorylation
G9457_16600	COG3706	GGDEF domain
G9457_16600	COG5001	Diguanylate cyclase
G9457_16600	COG2203	Gaf domain
G9457_16605	COG3089	Belongs to the UPF0270 family
G9457_16630	COG0463	Glycosyl transferase, family 2
G9457_16640	COG0726	polysaccharide deacetylase
G9457_16645	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
G9457_16650	COG2076	Multidrug Resistance protein
G9457_16660	COG3954	Phosphoribulokinase
G9457_16675	COG1765	OsmC-like protein
G9457_16690	COG3397	chitin binding
G9457_16725	COG3655	Transcriptional regulator
G9457_16735	COG2814	Major facilitator Superfamily
G9457_16740	COG4771	TonB-dependent receptor
G9457_16760	COG0748	coenzyme F420 binding
G9457_16765	COG3721	Heme iron utilization protein
G9457_16775	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
G9457_16800	COG0488	(ABC) transporter
G9457_16810	COG2252	PERMEase
G9457_16815	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
G9457_16820	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
G9457_16825	COG3178	'Phosphotransferase
G9457_16830	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
G9457_16840	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
G9457_16845	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
G9457_16850	COG2967	ApaG domain
G9457_16855	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
G9457_16870	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
G9457_16890	COG0318	PFAM AMP-dependent synthetase and ligase
G9457_16895	COG3314	Sporulation integral membrane protein YlbJ
G9457_16900	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
G9457_16905	COG0211	Belongs to the bacterial ribosomal protein bL27 family
G9457_16910	COG0261	This protein binds to 23S rRNA in the presence of protein L20
G9457_16915	COG0142	geranyltranstransferase activity
G9457_16920	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
G9457_16925	COG0330	HflC and HflK could
G9457_16930	COG0330	HflC and HflK could
G9457_16935	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
G9457_16940	COG1923	regulation of RNA biosynthetic process
G9457_16945	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
G9457_16950	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
G9457_16960	COG0802	atpase or kinase
G9457_16965	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
G9457_16965	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
G9457_16985	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
G9457_16990	COG2011	ABC-type metal ion transport system permease component
G9457_16995	COG1464	Belongs to the NlpA lipoprotein family
G9457_17005	COG0840	transmembrane signaling receptor activity
G9457_17030	COG5002	protein histidine kinase activity
G9457_17030	COG2198	Histidine kinase
G9457_17030	COG0784	Response regulator, receiver
G9457_17065	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
G9457_17070	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
G9457_17080	COG2716	regulation of RNA biosynthetic process
G9457_17085	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
G9457_17090	COG3013	Belongs to the UPF0304 family
G9457_17100	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
G9457_17105	COG0857	belongs to the CobB CobQ family
G9457_17105	COG0280	phosphate acetyltransferase
G9457_17110	COG0440	acetolactate synthase activity
G9457_17115	COG0028	Belongs to the TPP enzyme family
G9457_17130	COG0671	phosphoesterase, PA-phosphatase related
G9457_17140	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
G9457_17145	COG0473	3-isopropylmalate dehydrogenase activity
G9457_17150	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
G9457_17155	COG0066	3-isopropylmalate dehydratase activity
G9457_17170	COG4143	(ABC) transporter
G9457_17175	COG1178	ABC-type Fe3 transport system permease component
G9457_17180	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
G9457_17185	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
G9457_17195	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
G9457_17225	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
G9457_17230	COG0564	pseudouridine synthase activity
G9457_17240	COG5001	Diguanylate cyclase
G9457_17240	COG3300	MHYT domain
G9457_17250	COG0459	protein refolding
G9457_17255	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
G9457_17260	COG0534	Mate efflux family protein
G9457_17265	COG3030	protein affecting phage T7 exclusion by the F plasmid
G9457_17270	COG1027	Aspartate ammonia-lyase
G9457_17275	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
G9457_17285	COG0477	Major facilitator Superfamily
G9457_17295	COG3227	Zinc metalloprotease (Elastase)
G9457_17300	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
G9457_17305	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
G9457_17320	COG0673	inositol 2-dehydrogenase activity
G9457_17330	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
G9457_17335	COG0635	Involved in the biosynthesis of porphyrin-containing compound
G9457_17340	COG3036	rescue of stalled ribosome
G9457_17345	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
G9457_17355	COG0138	bifunctional purine biosynthesis protein purh
G9457_17360	COG0151	Belongs to the GarS family
G9457_17400	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
G9457_17405	COG0358	DNA primase activity
G9457_17410	COG1610	YqeY-like protein
G9457_17415	COG0828	Belongs to the bacterial ribosomal protein bS21 family
G9457_17420	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
G9457_17430	COG1388	LysM domain
G9457_17430	COG4942	peptidase
G9457_17435	COG1238	metal cluster binding
G9457_17440	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
G9457_17445	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
G9457_17450	COG0585	pseudouridine synthase activity
G9457_17460	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
G9457_17465	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
G9457_17470	COG0148	phosphopyruvate hydratase activity
G9457_17475	COG0504	CTP synthase activity
G9457_17480	COG3956	TIGRFAM MazG family protein
G9457_17485	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
G9457_17490	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
G9457_17500	COG4807	Protein conserved in bacteria
G9457_17505	COG3023	N-Acetylmuramoyl-L-alanine amidase
G9457_17510	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
G9457_17515	COG1381	Involved in DNA repair and RecF pathway recombination
G9457_17525	COG0571	ribonuclease III activity
G9457_17535	COG0481	GTPase activity
G9457_17550	COG3073	An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E
G9457_17555	COG1595	DNA-templated transcription, initiation
G9457_17560	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
G9457_17610	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
G9457_17615	COG0191	fructose-bisphosphate aldolase activity
G9457_17620	COG0126	phosphoglycerate kinase activity
G9457_17625	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
G9457_17630	COG1940	carbohydrate kinase activity
G9457_17655	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
G9457_17670	COG1136	(ABC) transporter
G9457_17730	COG5433	transposase activity
G9457_17735	COG0529	Catalyzes the synthesis of activated sulfate
G9457_17740	COG0471	metal ion transport
G9457_17740	COG3273	potassium ion transport
G9457_17745	COG2895	sulfate adenylyltransferase (ATP) activity
G9457_17750	COG0175	sulfate reduction
G9457_17755	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
G9457_17755	COG1648	precorrin-2 dehydrogenase activity
G9457_17760	COG0330	HflC and HflK could
G9457_17765	COG1585	Membrane protein implicated in regulation of membrane protease activity
G9457_17770	COG0517	IMP dehydrogenase activity
G9457_17770	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
G9457_17775	COG0488	(ABC) transporter
G9457_17785	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
G9457_17820	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
G9457_17825	COG1376	ErfK ybiS ycfS ynhG family protein
G9457_17830	COG0668	transmembrane transport
G9457_17840	COG2731	YhcH YjgK YiaL family protein
G9457_17850	COG1794	racemase activity, acting on amino acids and derivatives
G9457_17865	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
G9457_17890	COG0733	neurotransmitter:sodium symporter activity
G9457_17900	COG0733	neurotransmitter:sodium symporter activity
G9457_17915	COG0561	phosphatase activity
G9457_17950	COG1846	Transcriptional regulator
G9457_17955	COG1764	response to oxidative stress
G9457_17960	COG2130	NADP-dependent
G9457_17980	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
G9457_17985	COG1349	DNA-binding transcription factor activity
G9457_18025	COG1028	Short-chain dehydrogenase reductase Sdr
G9457_18035	COG2982	Protein involved in outer membrane biogenesis
G9457_18040	COG1505	serine-type exopeptidase activity
G9457_18055	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
G9457_18060	COG0745	RESPONSE REGULATOR receiver
G9457_18065	COG2205	protein histidine kinase activity
G9457_18070	COG2816	NAD+ diphosphatase activity
G9457_18100	COG0316	Belongs to the HesB IscA family
G9457_18110	COG0038	chloride channel
G9457_18115	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
G9457_18130	COG0671	phosphoesterase, PA-phosphatase related
G9457_18140	COG3437	response regulator, receiver
G9457_18140	COG0784	Response regulator, receiver
G9457_18145	COG0583	DNA-binding transcription factor activity
G9457_18150	COG2076	Multidrug Resistance protein
G9457_18160	COG0346	lactoylglutathione lyase activity
G9457_18165	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
G9457_18170	COG1643	Atp-dependent helicase
G9457_18180	COG1489	DNA binding
G9457_18185	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
G9457_18190	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
G9457_18195	COG0617	tRNA 3'-terminal CCA addition
G9457_18200	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
G9457_18205	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
G9457_18210	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
G9457_18220	COG0842	Transport permease protein
G9457_18225	COG1131	(ABC) transporter
G9457_18240	COG0163	prenyltransferase activity
G9457_18245	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
G9457_18250	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
G9457_18255	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
G9457_18265	COG0506	proline dehydrogenase activity
G9457_18265	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
G9457_18265	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
G9457_18270	COG4991	sh3 domain protein
G9457_18275	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
G9457_18295	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
G9457_18300	COG1640	4-alpha-glucanotransferase
G9457_18305	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
G9457_18310	COG0676	glucose-6-phosphate 1-epimerase activity
G9457_18315	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
G9457_18320	COG0840	transmembrane signaling receptor activity
G9457_18385	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
G9457_18390	COG2885	chlorophyll binding
G9457_18395	COG0823	Involved in the tonB-independent uptake of proteins
G9457_18410	COG0811	peptide transport
G9457_18415	COG0824	Thioesterase
G9457_18420	COG3790	cyd operon protein YbgE
G9457_18425	COG4890	Cyd operon protein YbgT
G9457_18430	COG1294	oxidase, subunit
G9457_18435	COG1271	oxidase subunit
G9457_18440	COG2255	four-way junction helicase activity
G9457_18445	COG0632	four-way junction helicase activity
G9457_18455	COG0442	prolyl-tRNA aminoacylation
G9457_18465	COG1902	pentaerythritol trinitrate reductase activity
G9457_18475	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
G9457_18505	COG0714	Associated with various cellular activities
G9457_18515	COG0456	acetyltransferase
G9457_18525	COG1022	Amp-dependent synthetase and ligase
G9457_18535	COG2918	glutathione biosynthetic process
G9457_18540	COG0612	Peptidase, M16
G9457_18545	COG1238	metal cluster binding
G9457_18550	COG1064	alcohol dehydrogenase
G9457_18580	COG0359	binds to the 23S rRNA
G9457_18585	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
G9457_18590	COG0360	Binds together with S18 to 16S ribosomal RNA
G9457_18595	COG1914	H( )-stimulated, divalent metal cation uptake system
G9457_18600	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
G9457_18625	COG2153	protein acetylation
G9457_18635	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
G9457_18640	COG0557	exoribonuclease II activity
G9457_18645	COG3706	GGDEF domain
G9457_18650	COG1854	S-ribosylhomocysteine lyase activity
G9457_18665	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
G9457_18665	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
G9457_18705	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
G9457_18710	COG1047	Peptidyl-prolyl cis-trans
G9457_18715	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
G9457_18720	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
G9457_18725	COG0196	riboflavin kinase activity
G9457_18730	COG0728	peptidoglycan biosynthetic process
G9457_18735	COG0268	Binds directly to 16S ribosomal RNA
G9457_18740	COG0640	Transcriptional regulator
G9457_18745	COG0583	DNA-binding transcription factor activity
G9457_18750	COG4974	Belongs to the 'phage' integrase family
G9457_18850	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
G9457_18865	COG4695	Portal protein
G9457_19020	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
G9457_19025	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
G9457_19030	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
G9457_19040	COG1051	belongs to the nudix hydrolase family
G9457_19045	COG3066	DNA modification
G9457_19055	COG0335	large ribosomal subunit rRNA binding
G9457_19060	COG0336	Belongs to the RNA methyltransferase TrmD family
G9457_19065	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
G9457_19070	COG0228	four-way junction DNA binding
G9457_19075	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
G9457_19080	COG4137	Cytochrome C assembly protein
G9457_19085	COG4536	flavin adenine dinucleotide binding
G9457_19090	COG1959	2 iron, 2 sulfur cluster binding
G9457_19095	COG1017	nitric oxide dioxygenase activity
G9457_19095	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
G9457_19100	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
G9457_19105	COG0039	L-malate dehydrogenase activity
G9457_19110	COG4160	amino acid transport
G9457_19115	COG4215	(ABC) transporter
G9457_19120	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
G9457_19125	COG1126	abc transporter atp-binding protein
G9457_19130	COG1438	arginine binding
G9457_19135	COG2837	iron assimilation
G9457_19140	COG3842	ATPase activity
G9457_19150	COG1840	ABC-type Fe3 transport system, periplasmic component
G9457_19155	COG0347	Belongs to the P(II) protein family
G9457_19170	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
G9457_19190	COG1929	Belongs to the glycerate kinase type-1 family
G9457_19195	COG2610	gluconate transmembrane transporter activity
G9457_19200	COG3835	regulator
G9457_19205	COG3112	Uncharacterised protein family (UPF0231)
G9457_19220	COG0840	transmembrane signaling receptor activity
G9457_19225	COG3568	Endonuclease Exonuclease Phosphatase
G9457_19240	COG0513	Belongs to the DEAD box helicase family
G9457_19280	COG1448	Aminotransferase
G9457_19300	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
G9457_19305	COG1328	CTP reductase activity
G9457_19340	COG1215	transferase activity, transferring glycosyl groups
G9457_19345	COG0726	polysaccharide deacetylase
G9457_19345	COG1649	PFAM Uncharacterised BCR, COG1649
G9457_19380	COG0840	transmembrane signaling receptor activity
G9457_19385	COG3397	chitin binding
G9457_19390	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
G9457_19395	COG1126	abc transporter atp-binding protein
G9457_19405	COG0765	amino acid transport
G9457_19410	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
G9457_19415	COG0583	DNA-binding transcription factor activity
G9457_19420	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
G9457_19425	COG4208	sulfate ABC transporter
G9457_19440	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
G9457_19450	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
G9457_19455	COG3174	membrane
G9457_19460	COG0110	maltose O-acetyltransferase activity
G9457_19490	COG1942	4-Oxalocrotonate Tautomerase
G9457_19500	COG0583	DNA-binding transcription factor activity
G9457_19505	COG0165	Argininosuccinate lyase
G9457_19510	COG0137	argininosuccinate synthase activity
G9457_19520	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
G9457_19525	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
G9457_19535	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
G9457_19545	COG2072	flavoprotein involved in K transport
G9457_19550	COG1393	Belongs to the ArsC family
G9457_19555	COG0798	PFAM Bile acid sodium symporter
G9457_19575	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
G9457_19595	COG3068	Protein conserved in bacteria
G9457_19605	COG0739	heme binding
G9457_19625	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
G9457_19630	COG1121	(ABC) transporter
G9457_19635	COG1108	ABC-type Mn2 Zn2 transport systems permease components
G9457_19640	COG0583	DNA-binding transcription factor activity
G9457_19650	COG1573	uracil-dna glycosylase
G9457_19665	COG2827	Endonuclease containing a URI domain
G9457_19685	COG0204	Acyl-transferase
G9457_19705	COG3118	belongs to the thioredoxin family
G9457_19710	COG2259	Doxx family
G9457_19795	COG1051	belongs to the nudix hydrolase family
G9457_19800	COG3150	esterase
G9457_19810	COG3151	Protein conserved in bacteria
G9457_19815	COG0494	nUDIX hydrolase
G9457_19820	COG1538	Outer membrane efflux protein
G9457_19825	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
G9457_19825	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
G9457_19830	COG1560	Kdo2-lipid A biosynthetic process
G9457_19845	COG1392	Phosphate transport regulator
G9457_19850	COG0306	phosphate transporter
G9457_19855	COG0617	tRNA 3'-terminal CCA addition
G9457_19860	COG3267	Type II secretory pathway component ExeA
G9457_19860	COG3409	Peptidoglycan-binding domain 1 protein
G9457_19870	COG1194	a g-specific adenine glycosylase
G9457_19875	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
G9457_19885	COG3111	PFAM Bacterial OB fold (BOF) protein
G9457_19890	COG3240	lipase activity
G9457_19905	COG3009	Protein conserved in bacteria
G9457_19910	COG3008	intermembrane lipid transfer
G9457_19910	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
G9457_19915	COG2995	paraquat-inducible protein a
G9457_19925	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
G9457_19940	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
G9457_19945	COG2813	Specifically methylates the guanine in position
G9457_19950	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
G9457_19955	COG0297	glycogen (starch) synthase activity
G9457_19990	COG1757	Na H antiporter
G9457_20000	COG0110	maltose O-acetyltransferase activity
G9457_20005	COG0366	Alpha amylase catalytic
G9457_20010	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
G9457_20010	COG1263	PTS System
G9457_20025	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
G9457_20030	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
G9457_20035	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
G9457_20035	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
G9457_20040	COG2723	6-phospho-beta-galactosidase activity
G9457_20045	COG1447	Phosphotransferase system cellobiose-specific component IIA
G9457_20050	COG1940	carbohydrate kinase activity
G9457_20060	COG1609	Transcriptional regulator
G9457_20070	COG0252	asparaginase activity
G9457_20085	COG1803	Methylglyoxal synthase
G9457_20110	COG1444	tRNA N-acetyltransferase activity
G9457_20115	COG1028	Short-chain dehydrogenase reductase Sdr
G9457_20120	COG0784	Response regulator, receiver
G9457_20120	COG0835	chemotaxis
G9457_20270	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
G9457_20275	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
G9457_20295	COG0523	cobalamin synthesis protein
G9457_20305	COG1280	lysine exporter protein (LysE YggA)
G9457_20315	COG0583	DNA-binding transcription factor activity
G9457_20320	COG1028	Short-chain dehydrogenase reductase Sdr
G9457_20325	COG2200	EAL domain
G9457_20330	COG1049	propionate catabolic process, 2-methylcitrate cycle
G9457_20340	COG0840	transmembrane signaling receptor activity
G9457_20345	COG0840	transmembrane signaling receptor activity
G9457_20355	COG5002	protein histidine kinase activity
G9457_20355	COG5001	Diguanylate cyclase
G9457_20355	COG3447	MASE1 domain protein
G9457_20360	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
G9457_20365	COG0508	dehydrogenase complex catalyzes the overall conversion of
G9457_20370	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
G9457_20375	COG2186	Transcriptional regulator
G9457_20415	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
G9457_20425	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
G9457_20435	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
G9457_20440	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
G9457_20445	COG0494	nUDIX hydrolase
G9457_20455	COG0653	protein targeting
G9457_20465	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
G9457_20470	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
G9457_20475	COG0849	cell division
G9457_20480	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
G9457_20485	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
G9457_20490	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
G9457_20495	COG0772	Belongs to the SEDS family
G9457_20500	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
G9457_20505	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
G9457_20510	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
G9457_20520	COG0768	penicillin binding
G9457_20525	COG3116	cell division
G9457_20530	COG0275	rRNA processing
G9457_20535	COG2001	Belongs to the MraZ family
G9457_20545	COG0741	lytic transglycosylase activity
G9457_20545	COG1388	LysM domain
G9457_20550	COG1360	Flagellar Motor Protein
G9457_20555	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
G9457_20560	COG1191	sigma factor activity
G9457_20585	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
G9457_20590	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
G9457_20620	COG1256	bacterial-type flagellum assembly
G9457_20620	COG4786	Flagellar basal body rod
G9457_20630	COG1706	bacterial-type flagellum-dependent cell motility
G9457_20635	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
G9457_20640	COG4786	Flagellar basal body rod
G9457_20645	COG4786	Flagellar basal body rod
G9457_20650	COG1749	Flagellar hook protein flgE
G9457_20655	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
G9457_20665	COG1815	bacterial-type flagellum-dependent cell motility
G9457_20675	COG2747	anti-sigma28 factor FlgM
G9457_20700	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
G9457_20710	COG1677	Flagellar hook-basal body complex protein FliE
G9457_20765	COG2197	response regulator
G9457_20770	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
G9457_20775	COG2199	diguanylate cyclase activity
G9457_20780	COG1278	Cold shock
G9457_20790	COG3706	GGDEF domain
G9457_20815	COG0347	Belongs to the P(II) protein family
G9457_20835	COG5433	transposase activity
G9457_20845	COG0346	lactoylglutathione lyase activity
G9457_20865	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
G9457_20870	COG1074	ATP-dependent DNA helicase activity
G9457_20875	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
G9457_20880	COG2259	Doxx family
G9457_20885	COG1741	Belongs to the pirin family
G9457_20895	COG0583	DNA-binding transcription factor activity
G9457_20920	COG1176	ABC-type spermidine putrescine transport system, permease component I
G9457_20930	COG3842	ATPase activity
G9457_20940	COG2199	diguanylate cyclase activity
G9457_20940	COG2203	Gaf domain
G9457_20960	COG1247	-acetyltransferase
G9457_20965	COG0753	catalase activity
G9457_20990	COG0494	nUDIX hydrolase
G9457_20995	COG0628	permease
G9457_21000	COG3284	Transcriptional regulator
G9457_21010	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
G9457_21010	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
G9457_21010	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
G9457_21015	COG1461	Dihydroxyacetone kinase
G9457_21020	COG2376	Dihydroxyacetone kinase
G9457_21025	COG2252	PERMEase
G9457_21075	COG0203	ribosomal protein L17
G9457_21080	COG0202	RNA polymerase activity
G9457_21085	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
G9457_21090	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
G9457_21095	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
G9457_21100	COG0257	Belongs to the bacterial ribosomal protein bL36 family
G9457_21105	COG0201	protein transport
G9457_21110	COG0200	Binds to the 23S rRNA
G9457_21115	COG1841	ribosomal large subunit assembly
G9457_21120	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
G9457_21125	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
G9457_21130	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
G9457_21135	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
G9457_21140	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
G9457_21145	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
G9457_21150	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
G9457_21155	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
G9457_21160	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
G9457_21165	COG0255	Belongs to the universal ribosomal protein uL29 family
G9457_21170	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
G9457_21175	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
G9457_21180	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
G9457_21185	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
G9457_21190	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
G9457_21195	COG0089	rRNA binding
G9457_21200	COG0088	Forms part of the polypeptide exit tunnel
G9457_21205	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
G9457_21210	COG0051	transcription antitermination factor activity, RNA binding
G9457_21230	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
G9457_21235	COG2183	response to ionizing radiation
G9457_21255	COG0596	Alpha beta hydrolase
G9457_21260	COG1040	competence protein
G9457_21265	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
G9457_21265	COG0316	Belongs to the HesB IscA family
G9457_21270	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
G9457_21275	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
G9457_21280	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
G9457_21285	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
G9457_21290	COG4942	peptidase
G9457_21300	COG1609	Transcriptional regulator
G9457_21305	COG0800	Aldolase
G9457_21310	COG0129	dihydroxy-acid dehydratase activity
G9457_21315	COG3265	gluconokinase activity
G9457_21320	COG2610	gluconate transmembrane transporter activity
G9457_21325	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
G9457_21330	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
G9457_21340	COG0456	acetyltransferase
G9457_21350	COG1490	D-aminoacyl-tRNA deacylase activity
G9457_21355	COG1295	ribonuclease BN
G9457_21360	COG1217	gtp-binding protein TYPA
G9457_21365	COG0174	glutamine synthetase
G9457_21375	COG3852	Histidine kinase
G9457_21380	COG2204	response regulator
G9457_21385	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
G9457_21390	COG0635	Involved in the biosynthesis of porphyrin-containing compound
G9457_21400	COG3078	GTPase activator activity
G9457_21410	COG0218	Necessary for normal cell division and for the maintenance of normal septation
G9457_21420	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
G9457_21425	COG0408	coproporphyrinogen oxidase activity
G9457_21430	COG0009	L-threonylcarbamoyladenylate synthase
G9457_21440	COG0551	DNA topoisomerase type I activity
G9457_21445	COG2922	Belongs to the Smg family
G9457_21450	COG0758	DNA mediated transformation
G9457_21455	COG1652	LysM domain
G9457_21460	COG0242	peptide deformylase activity
G9457_21465	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
G9457_21470	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
G9457_21470	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
G9457_21475	COG0569	domain protein
G9457_21480	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
G9457_21505	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
G9457_21510	COG0686	Belongs to the AlaDH PNT family
G9457_21515	COG0519	Catalyzes the synthesis of GMP from XMP
G9457_21515	COG0518	GMP synthase (glutamine-hydrolyzing) activity
G9457_21525	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
G9457_21535	COG1012	belongs to the aldehyde dehydrogenase family
G9457_21545	COG2962	Rard protein
G9457_21555	COG1280	lysine exporter protein (LysE YggA)
G9457_21580	COG2116	formate transmembrane transporter activity
G9457_21585	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
G9457_21585	COG1648	precorrin-2 dehydrogenase activity
G9457_21590	COG2239	Acts as a magnesium transporter
G9457_21600	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
G9457_21605	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
G9457_21615	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
G9457_21625	COG0514	ATP-dependent DNA helicase (RecQ)
G9457_21630	COG2050	protein possibly involved in aromatic compounds catabolism
G9457_21645	COG2258	MOSC domain
G9457_21650	COG1177	transmembrane transport
G9457_21655	COG1176	ABC-type spermidine putrescine transport system, permease component I
G9457_21660	COG3842	ATPase activity
G9457_21680	COG0174	glutamine synthetase
G9457_21700	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
G9457_21705	COG0443	Heat shock 70 kDa protein
G9457_21720	COG0366	Alpha amylase catalytic
G9457_21725	COG1086	Polysaccharide biosynthesis protein
G9457_21730	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
G9457_21755	COG0318	PFAM AMP-dependent synthetase and ligase
G9457_21775	COG1083	cytidylyl-transferase
G9457_21785	COG2089	acid synthase
G9457_21820	COG5433	transposase activity
G9457_21830	COG4310	Domain of unknown function (DUF2172)
G9457_21865	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
G9457_21870	COG0745	RESPONSE REGULATOR receiver
G9457_21875	COG2205	protein histidine kinase activity
G9457_21885	COG0281	malic enzyme
G9457_21890	COG0702	epimerase
G9457_21895	COG0254	rRNA binding
G9457_21900	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
G9457_21910	COG1309	transcriptional regulator
G9457_21930	COG0129	dihydroxy-acid dehydratase activity
G9457_21940	COG3978	acetolactate synthase activity
G9457_21950	COG0606	chelatase, subunit chli
G9457_21960	COG1683	Conserved Protein
G9457_21970	COG1335	isochorismatase
G9457_21980	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
G9457_21985	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
G9457_21990	COG3639	organic phosphonate transmembrane transporter activity
G9457_21995	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
G9457_22000	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
G9457_22010	COG3084	Protein conserved in bacteria
G9457_22015	COG2203	Gaf domain
G9457_22015	COG3706	GGDEF domain
G9457_22015	COG4251	negative regulation of phosphorylation
G9457_22015	COG5001	Diguanylate cyclase
G9457_22030	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
G9457_22040	COG1561	YicC-like family, N-terminal region
G9457_22070	COG0438	transferase activity, transferring glycosyl groups
G9457_22075	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
G9457_22090	COG1063	alcohol dehydrogenase
G9457_22105	COG0210	DNA helicase
G9457_22110	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
G9457_22115	COG2166	iron-sulfur cluster assembly
G9457_22120	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
G9457_22150	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
G9457_22155	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
G9457_22160	COG1739	Uncharacterized protein family UPF0029
G9457_22170	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
G9457_22175	COG1250	3-hydroxyacyl-CoA dehydrogenase
G9457_22175	COG1024	Enoyl-CoA hydratase
G9457_22180	COG0183	Belongs to the thiolase family
G9457_22205	COG0425	Belongs to the sulfur carrier protein TusA family
G9457_22210	COG0251	oxidation-reduction process
G9457_22215	COG2885	chlorophyll binding
G9457_22220	COG2818	Glycosylase
G9457_22225	COG0752	glycyl-tRNA synthetase alpha subunit
G9457_22230	COG0751	glycine-tRNA ligase activity
G9457_22255	COG3604	Transcriptional regulator
G9457_22265	COG0446	pyridine nucleotide-disulphide oxidoreductase
G9457_22275	COG0348	domain, Protein
G9457_22280	COG0814	amino acid
G9457_22295	COG2199	diguanylate cyclase activity
G9457_22295	COG2200	EAL domain
G9457_22295	COG2202	Pas domain
G9457_22330	COG3328	transposase activity
G9457_22365	COG1609	Transcriptional regulator
G9457_22405	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
G9457_22430	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
G9457_22445	COG3118	belongs to the thioredoxin family
G9457_22450	COG0513	Belongs to the DEAD box helicase family
G9457_22455	COG0248	Ppx GppA phosphatase
G9457_22465	COG0742	ribosomal rna small subunit methyltransferase
G9457_22470	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
G9457_22490	COG0084	hydrolase, TatD family'
G9457_22495	COG0805	protein transport
G9457_22500	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
G9457_22510	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
G9457_22515	COG3165	ubiquinone biosynthetic process from chorismate
G9457_22525	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
G9457_22530	COG0402	S-adenosylhomocysteine deaminase activity
G9457_22570	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
G9457_22575	COG0848	biopolymer transport protein
G9457_22580	COG0811	peptide transport
G9457_22585	COG0811	peptide transport
G9457_22595	COG2771	luxR family
G9457_22600	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
G9457_22605	COG1349	DNA-binding transcription factor activity
G9457_22610	COG0745	RESPONSE REGULATOR receiver
G9457_22615	COG2205	protein histidine kinase activity
G9457_22625	COG4452	Inner membrane protein CreD
G9457_22630	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
G9457_22635	COG0355	proton-transporting ATP synthase activity, rotational mechanism
G9457_22640	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
G9457_22645	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
G9457_22650	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
G9457_22655	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
G9457_22660	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
G9457_22670	COG0356	it plays a direct role in the translocation of protons across the membrane
G9457_22675	COG3312	ion transport
G9457_22680	COG1475	DNA binding
G9457_22685	COG1192	Involved in chromosome partitioning
G9457_22690	COG0357	Ribosomal RNA small subunit methyltransferase G
G9457_22695	COG0445	tRNA wobble uridine modification
G9457_22700	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
G9457_22705	COG4774	siderophore transport
G9457_22710	COG4615	Cyclic peptide transporter
G9457_22715	COG1120	ATPase activity
G9457_22720	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
G9457_22730	COG4774	siderophore transport
G9457_22735	COG4607	ABC-type enterochelin transport system periplasmic component
G9457_22740	COG4604	ABC transporter, ATP-binding protein
G9457_22745	COG4605	iron ion homeostasis
G9457_22750	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
G9457_22755	COG1132	(ABC) transporter
G9457_22760	COG2375	cellular response to nickel ion
G9457_22760	COG1132	(ABC) transporter
G9457_22770	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
G9457_22780	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
G9457_22795	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
G9457_22800	COG0706	membrane insertase activity
G9457_22805	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
G9457_22810	COG0594	ribonuclease P activity
G9457_22815	COG0230	Belongs to the bacterial ribosomal protein bL34 family
G9457_22820	COG1126	abc transporter atp-binding protein
G9457_22860	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
G9457_22900	COG1271	oxidase subunit
G9457_22905	COG1294	oxidase, subunit
G9457_22915	COG1454	alcohol dehydrogenase
G9457_22975	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
G9457_23165	COG2974	May be involved in recombination
G9457_23200	COG1525	nuclease
G9457_23225	COG1192	Involved in chromosome partitioning
G9457_23285	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
G9457_23290	COG1061	Type III restriction enzyme res subunit
G9457_23295	COG1002	Type II restriction enzyme, methylase subunits
G9457_23310	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
G9457_23495	COG0714	Associated with various cellular activities
G9457_23560	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
G9457_23640	COG3409	Peptidoglycan-binding domain 1 protein
G9457_23640	COG3267	Type II secretory pathway component ExeA
G9457_23700	COG0778	Nitroreductase
G9457_23705	COG0583	DNA-binding transcription factor activity
G9457_23800	COG4974	Belongs to the 'phage' integrase family
G9457_23820	COG3550	peptidyl-serine autophosphorylation
G9457_23925	COG0697	spore germination
G9457_23980	COG3039	Transposase
G9457_23995	COG3039	Transposase
G9457_24040	COG0426	domain, Protein
G9457_24040	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
G9457_24050	COG0840	transmembrane signaling receptor activity
G9457_24065	COG1028	Short-chain dehydrogenase reductase Sdr
G9457_24075	COG0583	DNA-binding transcription factor activity
G9457_24085	COG3093	addiction module antidote protein HigA
G9457_24185	COG1484	DNA-dependent DNA replication
G9457_24230	COG1192	Involved in chromosome partitioning
G9457_24240	COG2916	Histone family protein nucleoid-structuring protein H-NS
G9457_24335	COG1192	Involved in chromosome partitioning
G9457_24360	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs