locus-tag	class	description
C5P03_00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
C5P03_00010	COG0592	DNA-directed DNA polymerase activity
C5P03_00020	COG0187	DNA topoisomerase II activity
C5P03_00035	COG2378	regulation of single-species biofilm formation
C5P03_00040	COG0071	Belongs to the small heat shock protein (HSP20) family
C5P03_00045	COG0071	Belongs to the small heat shock protein (HSP20) family
C5P03_00060	COG3977	Valine--pyruvate aminotransferase
C5P03_00085	COG0745	RESPONSE REGULATOR receiver
C5P03_00090	COG2205	protein histidine kinase activity
C5P03_00115	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
C5P03_00120	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C5P03_00120	COG4191	Histidine kinase
C5P03_00125	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
C5P03_00130	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
C5P03_00135	COG1309	transcriptional regulator
C5P03_00165	COG0561	phosphatase activity
C5P03_00170	COG2267	carboxylic ester hydrolase activity
C5P03_00175	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
C5P03_00180	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
C5P03_00185	COG1758	RNA polymerase activity
C5P03_00190	COG0194	GDP metabolic process
C5P03_00200	COG0859	PFAM glycosyl transferase family 9
C5P03_00205	COG3642	lipopolysaccharide core region biosynthetic process
C5P03_00245	COG0589	response to stress
C5P03_00250	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
C5P03_00260	COG1528	Iron-storage protein
C5P03_00265	COG2081	HI0933 family
C5P03_00300	COG4584	PFAM Integrase catalytic
C5P03_00305	COG1484	DNA-dependent DNA replication
C5P03_00320	COG2197	response regulator
C5P03_00325	COG2205	protein histidine kinase activity
C5P03_00325	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C5P03_00335	COG2205	protein histidine kinase activity
C5P03_00335	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C5P03_00345	COG3275	phosphorelay sensor kinase activity
C5P03_00350	COG3279	Response regulator of the LytR AlgR family
C5P03_00355	COG2223	nitrite transmembrane transporter activity
C5P03_00360	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
C5P03_00365	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
C5P03_00380	COG0583	DNA-binding transcription factor activity
C5P03_00385	COG4206	TonB-dependent receptor
C5P03_00390	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
C5P03_00425	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
C5P03_00430	COG2166	iron-sulfur cluster assembly
C5P03_00435	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
C5P03_00440	COG0210	DNA helicase
C5P03_00455	COG1063	alcohol dehydrogenase
C5P03_00470	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
C5P03_00475	COG0438	transferase activity, transferring glycosyl groups
C5P03_00505	COG1561	YicC-like family, N-terminal region
C5P03_00515	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
C5P03_00530	COG5001	Diguanylate cyclase
C5P03_00530	COG4251	negative regulation of phosphorylation
C5P03_00530	COG3706	GGDEF domain
C5P03_00530	COG2203	Gaf domain
C5P03_00535	COG3084	Protein conserved in bacteria
C5P03_00545	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
C5P03_00550	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
C5P03_00555	COG3639	organic phosphonate transmembrane transporter activity
C5P03_00560	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
C5P03_00565	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
C5P03_00575	COG1335	isochorismatase
C5P03_00585	COG1683	Conserved Protein
C5P03_00590	COG0204	Acyl-transferase
C5P03_00610	COG3978	acetolactate synthase activity
C5P03_00615	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
C5P03_00620	COG0129	dihydroxy-acid dehydratase activity
C5P03_00640	COG1309	transcriptional regulator
C5P03_00650	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
C5P03_00655	COG0254	rRNA binding
C5P03_00660	COG0702	epimerase
C5P03_00665	COG0281	malic enzyme
C5P03_00675	COG2205	protein histidine kinase activity
C5P03_00680	COG0745	RESPONSE REGULATOR receiver
C5P03_00685	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
C5P03_00725	COG2089	acid synthase
C5P03_00735	COG1083	cytidylyl-transferase
C5P03_00755	COG0318	PFAM AMP-dependent synthetase and ligase
C5P03_00775	COG1442	glycosyl transferase family 8
C5P03_00795	COG1086	Polysaccharide biosynthesis protein
C5P03_00800	COG0366	Alpha amylase catalytic
C5P03_00815	COG0443	Heat shock 70 kDa protein
C5P03_00820	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
C5P03_00825	COG3045	CreA protein
C5P03_00835	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
C5P03_00840	COG0174	glutamine synthetase
C5P03_00860	COG3842	ATPase activity
C5P03_00865	COG1176	ABC-type spermidine putrescine transport system, permease component I
C5P03_00870	COG1177	transmembrane transport
C5P03_00875	COG2258	MOSC domain
C5P03_00895	COG2050	protein possibly involved in aromatic compounds catabolism
C5P03_00900	COG0514	ATP-dependent DNA helicase (RecQ)
C5P03_00910	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
C5P03_00920	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
C5P03_00925	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
C5P03_00935	COG2239	Acts as a magnesium transporter
C5P03_00940	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
C5P03_00940	COG1648	precorrin-2 dehydrogenase activity
C5P03_00945	COG2116	formate transmembrane transporter activity
C5P03_00950	COG2146	nitrite reductase [NAD(P)H] activity
C5P03_00955	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
C5P03_00970	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
C5P03_00975	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
C5P03_00985	COG0018	arginyl-trna synthetase
C5P03_00995	COG1595	DNA-templated transcription, initiation
C5P03_01005	COG1968	undecaprenyl-diphosphatase activity
C5P03_01010	COG0667	Aldo Keto reductase
C5P03_01015	COG2017	converts alpha-aldose to the beta-anomer
C5P03_01020	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
C5P03_01030	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
C5P03_01035	COG1609	Transcriptional regulator
C5P03_01090	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
C5P03_01095	COG1288	antiporter activity
C5P03_01105	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
C5P03_01110	COG0540	Belongs to the ATCase OTCase family
C5P03_01125	COG0688	phosphatidylethanolamine metabolic process
C5P03_01135	COG3040	lipid binding
C5P03_01145	COG1979	alcohol dehydrogenase
C5P03_01150	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
C5P03_01155	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
C5P03_01165	COG2964	Protein conserved in bacteria
C5P03_01170	COG3681	Belongs to the UPF0597 family
C5P03_01180	COG0446	pyridine nucleotide-disulphide oxidoreductase
C5P03_01185	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
C5P03_01190	COG0564	pseudouridine synthase activity
C5P03_01200	COG0542	response to heat
C5P03_01205	COG2502	aspartate--ammonia ligase
C5P03_01210	COG1522	sequence-specific DNA binding
C5P03_01225	COG0517	IMP dehydrogenase activity
C5P03_01225	COG0516	GMP reductase activity
C5P03_01230	COG1028	Short-chain dehydrogenase reductase Sdr
C5P03_01245	COG2205	protein histidine kinase activity
C5P03_01255	COG2204	response regulator
C5P03_01270	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
C5P03_01275	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
C5P03_01290	COG0745	RESPONSE REGULATOR receiver
C5P03_01295	COG2205	protein histidine kinase activity
C5P03_01305	COG0243	molybdopterin cofactor binding
C5P03_01310	COG3005	denitrification pathway
C5P03_01315	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
C5P03_01320	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
C5P03_01325	COG0569	domain protein
C5P03_01330	COG0812	UDP-N-acetylmuramate dehydrogenase activity
C5P03_01355	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
C5P03_01365	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
C5P03_01370	COG0250	Participates in transcription elongation, termination and antitermination
C5P03_01375	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
C5P03_01380	COG0081	regulation of translation
C5P03_01385	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
C5P03_01390	COG0222	ribosome binding
C5P03_01395	COG0085	RNA polymerase activity
C5P03_01400	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
C5P03_01405	COG2964	Protein conserved in bacteria
C5P03_01420	COG2923	Belongs to the DsrF TusC family
C5P03_01425	COG2168	tRNA wobble position uridine thiolation
C5P03_01430	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
C5P03_01435	COG0049	tRNA binding
C5P03_01440	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
C5P03_01445	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
C5P03_01450	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
C5P03_01475	COG2926	Belongs to the UPF0265 family
C5P03_01485	COG3028	Belongs to the UPF0307 family
C5P03_01490	COG0312	modulator of DNA gyrase
C5P03_01495	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
C5P03_01500	COG5007	Belongs to the BolA IbaG family
C5P03_01510	COG2854	intermembrane phospholipid transfer
C5P03_01515	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
C5P03_01520	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
C5P03_01525	COG1127	ABC transporter
C5P03_01530	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
C5P03_01530	COG0517	IMP dehydrogenase activity
C5P03_01535	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
C5P03_01540	COG3117	lipopolysaccharide transmembrane transporter activity
C5P03_01545	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
C5P03_01550	COG1137	ATPase activity
C5P03_01555	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
C5P03_01565	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
C5P03_01570	COG1660	Displays ATPase and GTPase activities
C5P03_01575	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
C5P03_01595	COG3964	amidohydrolase
C5P03_01630	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
C5P03_01635	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
C5P03_01645	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
C5P03_01650	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
C5P03_01655	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
C5P03_01660	COG0723	plastoquinol--plastocyanin reductase activity
C5P03_01665	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
C5P03_01670	COG2857	Cytochrome c1
C5P03_01675	COG0625	glutathione transferase activity
C5P03_01680	COG2969	positive regulation of protein catabolic process
C5P03_01685	COG2823	Periplasmic or secreted lipoprotein
C5P03_01690	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
C5P03_01700	COG3107	peptidoglycan biosynthetic process
C5P03_01705	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
C5P03_01730	COG1987	bacterial-type flagellum assembly
C5P03_01750	COG2204	response regulator
C5P03_01755	COG1677	Flagellar hook-basal body complex protein FliE
C5P03_01765	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
C5P03_01790	COG2747	anti-sigma28 factor FlgM
C5P03_01800	COG1815	bacterial-type flagellum-dependent cell motility
C5P03_01805	COG1558	bacterial-type flagellum-dependent cell motility
C5P03_01815	COG1749	Flagellar hook protein flgE
C5P03_01820	COG4786	Flagellar basal body rod
C5P03_01825	COG4786	Flagellar basal body rod
C5P03_01830	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
C5P03_01835	COG1706	bacterial-type flagellum-dependent cell motility
C5P03_01845	COG1256	bacterial-type flagellum assembly
C5P03_01865	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
C5P03_01880	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
C5P03_01905	COG1191	sigma factor activity
C5P03_01910	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
C5P03_01915	COG1360	Flagellar Motor Protein
C5P03_01925	COG1388	LysM domain
C5P03_01925	COG0741	lytic transglycosylase activity
C5P03_01935	COG2001	Belongs to the MraZ family
C5P03_01940	COG0275	rRNA processing
C5P03_01945	COG3116	cell division
C5P03_01950	COG0768	penicillin binding
C5P03_01960	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
C5P03_01965	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
C5P03_01970	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
C5P03_01975	COG0772	Belongs to the SEDS family
C5P03_01980	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
C5P03_01985	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
C5P03_01990	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
C5P03_01995	COG0849	cell division
C5P03_02000	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
C5P03_02005	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
C5P03_02015	COG0653	protein targeting
C5P03_02025	COG0494	nUDIX hydrolase
C5P03_02030	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
C5P03_02035	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
C5P03_02045	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
C5P03_02055	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
C5P03_02080	COG2186	Transcriptional regulator
C5P03_02085	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
C5P03_02090	COG0508	dehydrogenase complex catalyzes the overall conversion of
C5P03_02095	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
C5P03_02100	COG5001	Diguanylate cyclase
C5P03_02100	COG5002	protein histidine kinase activity
C5P03_02100	COG3447	MASE1 domain protein
C5P03_02110	COG0840	transmembrane signaling receptor activity
C5P03_02125	COG1049	propionate catabolic process, 2-methylcitrate cycle
C5P03_02130	COG2200	EAL domain
C5P03_02135	COG1028	Short-chain dehydrogenase reductase Sdr
C5P03_02140	COG0583	DNA-binding transcription factor activity
C5P03_02150	COG1280	lysine exporter protein (LysE YggA)
C5P03_02160	COG0523	cobalamin synthesis protein
C5P03_02165	COG0477	Major facilitator Superfamily
C5P03_02180	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
C5P03_02185	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
C5P03_02305	COG0835	chemotaxis
C5P03_02305	COG0784	Response regulator, receiver
C5P03_02310	COG1028	Short-chain dehydrogenase reductase Sdr
C5P03_02315	COG1444	tRNA N-acetyltransferase activity
C5P03_02340	COG1803	Methylglyoxal synthase
C5P03_02355	COG0252	asparaginase activity
C5P03_02365	COG1609	Transcriptional regulator
C5P03_02375	COG1940	carbohydrate kinase activity
C5P03_02380	COG1447	Phosphotransferase system cellobiose-specific component IIA
C5P03_02385	COG2723	6-phospho-beta-galactosidase activity
C5P03_02390	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
C5P03_02395	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
C5P03_02400	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
C5P03_02420	COG0366	Alpha amylase catalytic
C5P03_02425	COG0110	maltose O-acetyltransferase activity
C5P03_02435	COG1757	Na H antiporter
C5P03_02475	COG0297	glycogen (starch) synthase activity
C5P03_02480	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
C5P03_02485	COG2813	Specifically methylates the guanine in position
C5P03_02490	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
C5P03_02505	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
C5P03_02515	COG2995	paraquat-inducible protein a
C5P03_02520	COG3008	intermembrane lipid transfer
C5P03_02520	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
C5P03_02525	COG3009	Protein conserved in bacteria
C5P03_02540	COG3240	lipase activity
C5P03_02545	COG3111	PFAM Bacterial OB fold (BOF) protein
C5P03_02555	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
C5P03_02560	COG1194	a g-specific adenine glycosylase
C5P03_02570	COG3409	Peptidoglycan-binding domain 1 protein
C5P03_02570	COG3267	Type II secretory pathway component ExeA
C5P03_02575	COG0617	tRNA 3'-terminal CCA addition
C5P03_02580	COG0306	phosphate transporter
C5P03_02585	COG1392	Phosphate transport regulator
C5P03_02600	COG1560	Kdo2-lipid A biosynthetic process
C5P03_02605	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
C5P03_02605	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
C5P03_02610	COG1538	Outer membrane efflux protein
C5P03_02620	COG0494	nUDIX hydrolase
C5P03_02630	COG3151	Protein conserved in bacteria
C5P03_02640	COG3150	esterase
C5P03_02645	COG1051	belongs to the nudix hydrolase family
C5P03_02655	COG0187	DNA topoisomerase II activity
C5P03_02695	COG2259	Doxx family
C5P03_02700	COG3118	belongs to the thioredoxin family
C5P03_02720	COG0204	Acyl-transferase
C5P03_02725	COG1842	Phage shock protein A
C5P03_02740	COG2827	Endonuclease containing a URI domain
C5P03_02750	COG2962	Rard protein
C5P03_02755	COG1573	uracil-dna glycosylase
C5P03_02765	COG0583	DNA-binding transcription factor activity
C5P03_02770	COG1108	ABC-type Mn2 Zn2 transport systems permease components
C5P03_02775	COG1121	(ABC) transporter
C5P03_02780	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
C5P03_02800	COG0739	heme binding
C5P03_02810	COG3068	Protein conserved in bacteria
C5P03_02830	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
C5P03_02850	COG0798	PFAM Bile acid sodium symporter
C5P03_02855	COG1393	Belongs to the ArsC family
C5P03_02865	COG2072	flavoprotein involved in K transport
C5P03_02875	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
C5P03_02885	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
C5P03_02890	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
C5P03_02900	COG0137	argininosuccinate synthase activity
C5P03_02905	COG0165	Argininosuccinate lyase
C5P03_02910	COG0583	DNA-binding transcription factor activity
C5P03_02920	COG1942	4-Oxalocrotonate Tautomerase
C5P03_02950	COG0110	maltose O-acetyltransferase activity
C5P03_02955	COG3174	membrane
C5P03_02960	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
C5P03_02970	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
C5P03_02975	COG4208	sulfate ABC transporter
C5P03_02980	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
C5P03_02985	COG0583	DNA-binding transcription factor activity
C5P03_02990	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
C5P03_02995	COG0765	amino acid transport
C5P03_03005	COG1126	abc transporter atp-binding protein
C5P03_03010	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C5P03_03015	COG3397	chitin binding
C5P03_03020	COG0840	transmembrane signaling receptor activity
C5P03_03060	COG1215	transferase activity, transferring glycosyl groups
C5P03_03100	COG1328	CTP reductase activity
C5P03_03105	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
C5P03_03120	COG1448	Aminotransferase
C5P03_03160	COG0513	Belongs to the DEAD box helicase family
C5P03_03175	COG3568	Endonuclease Exonuclease Phosphatase
C5P03_03180	COG0840	transmembrane signaling receptor activity
C5P03_03195	COG3112	Uncharacterised protein family (UPF0231)
C5P03_03200	COG3835	regulator
C5P03_03205	COG2610	gluconate transmembrane transporter activity
C5P03_03205	COG2610	gluconate transmembrane transporter activity
C5P03_03210	COG1929	Belongs to the glycerate kinase type-1 family
C5P03_03230	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
C5P03_03245	COG0347	Belongs to the P(II) protein family
C5P03_03250	COG1840	ABC-type Fe3 transport system, periplasmic component
C5P03_03260	COG3842	ATPase activity
C5P03_03265	COG2837	iron assimilation
C5P03_03270	COG1438	arginine binding
C5P03_03275	COG1126	abc transporter atp-binding protein
C5P03_03280	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C5P03_03285	COG4215	(ABC) transporter
C5P03_03290	COG4160	amino acid transport
C5P03_03295	COG0039	L-malate dehydrogenase activity
C5P03_03300	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
C5P03_03305	COG1017	nitric oxide dioxygenase activity
C5P03_03305	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
C5P03_03310	COG1959	2 iron, 2 sulfur cluster binding
C5P03_03315	COG4536	flavin adenine dinucleotide binding
C5P03_03320	COG4137	Cytochrome C assembly protein
C5P03_03325	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
C5P03_03330	COG0228	four-way junction DNA binding
C5P03_03335	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
C5P03_03340	COG0336	Belongs to the RNA methyltransferase TrmD family
C5P03_03345	COG0335	large ribosomal subunit rRNA binding
C5P03_03355	COG3066	DNA modification
C5P03_03360	COG1051	belongs to the nudix hydrolase family
C5P03_03370	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
C5P03_03375	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
C5P03_03380	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
C5P03_03390	COG0583	DNA-binding transcription factor activity
C5P03_03395	COG0640	Transcriptional regulator
C5P03_03400	COG0268	Binds directly to 16S ribosomal RNA
C5P03_03405	COG0728	peptidoglycan biosynthetic process
C5P03_03410	COG0196	riboflavin kinase activity
C5P03_03415	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
C5P03_03420	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
C5P03_03425	COG1047	Peptidyl-prolyl cis-trans
C5P03_03430	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
C5P03_03435	COG4968	Prepilin-type N-terminal cleavage methylation domain
C5P03_03470	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
C5P03_03470	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
C5P03_03485	COG1854	S-ribosylhomocysteine lyase activity
C5P03_03490	COG3706	GGDEF domain
C5P03_03495	COG0557	exoribonuclease II activity
C5P03_03500	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
C5P03_03510	COG2153	protein acetylation
C5P03_03530	COG1914	H( )-stimulated, divalent metal cation uptake system
C5P03_03535	COG0360	Binds together with S18 to 16S ribosomal RNA
C5P03_03540	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
C5P03_03545	COG0359	binds to the 23S rRNA
C5P03_03575	COG1064	alcohol dehydrogenase
C5P03_03580	COG1238	metal cluster binding
C5P03_03585	COG0612	Peptidase, M16
C5P03_03590	COG2918	glutathione biosynthetic process
C5P03_03600	COG1022	Amp-dependent synthetase and ligase
C5P03_03610	COG0456	acetyltransferase
C5P03_03620	COG0714	Associated with various cellular activities
C5P03_03645	COG0745	RESPONSE REGULATOR receiver
C5P03_03645	COG3706	GGDEF domain
C5P03_03650	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
C5P03_03660	COG1902	pentaerythritol trinitrate reductase activity
C5P03_03670	COG0442	prolyl-tRNA aminoacylation
C5P03_03675	COG0840	transmembrane signaling receptor activity
C5P03_03680	COG0632	four-way junction helicase activity
C5P03_03685	COG2255	four-way junction helicase activity
C5P03_03690	COG1271	oxidase subunit
C5P03_03695	COG1294	oxidase, subunit
C5P03_03700	COG4890	Cyd operon protein YbgT
C5P03_03705	COG3790	cyd operon protein YbgE
C5P03_03710	COG0824	Thioesterase
C5P03_03715	COG0811	peptide transport
C5P03_03730	COG0823	Involved in the tonB-independent uptake of proteins
C5P03_03735	COG2885	chlorophyll binding
C5P03_03740	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
C5P03_03810	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
C5P03_03815	COG0676	glucose-6-phosphate 1-epimerase activity
C5P03_03820	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
C5P03_03825	COG1640	4-alpha-glucanotransferase
C5P03_03830	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
C5P03_03850	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
C5P03_03855	COG4991	sh3 domain protein
C5P03_03860	COG0506	proline dehydrogenase activity
C5P03_03860	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
C5P03_03860	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
C5P03_03870	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
C5P03_03875	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
C5P03_03880	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
C5P03_03885	COG0163	prenyltransferase activity
C5P03_03900	COG1131	(ABC) transporter
C5P03_03905	COG0842	Transport permease protein
C5P03_03915	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
C5P03_03920	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
C5P03_03925	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
C5P03_03930	COG0617	tRNA 3'-terminal CCA addition
C5P03_03935	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
C5P03_03940	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
C5P03_03945	COG1489	DNA binding
C5P03_03955	COG1643	Atp-dependent helicase
C5P03_03960	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
C5P03_03965	COG0346	lactoylglutathione lyase activity
C5P03_03975	COG2076	Multidrug Resistance protein
C5P03_03980	COG0583	DNA-binding transcription factor activity
C5P03_03985	COG3437	response regulator, receiver
C5P03_03985	COG0784	Response regulator, receiver
C5P03_03995	COG0671	phosphoesterase, PA-phosphatase related
C5P03_04010	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
C5P03_04015	COG0038	chloride channel
C5P03_04025	COG0316	Belongs to the HesB IscA family
C5P03_04055	COG1280	lysine exporter protein (LysE YggA)
C5P03_04060	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
C5P03_04075	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
C5P03_04105	COG0745	RESPONSE REGULATOR receiver
C5P03_04110	COG3104	oligopeptide transport
C5P03_04115	COG1210	Utp--glucose-1-phosphate uridylyltransferase
C5P03_04120	COG1555	photosystem II stabilization
C5P03_04130	COG2350	Protein conserved in bacteria
C5P03_04135	COG2917	probably involved in intracellular septation
C5P03_04140	COG0076	glutamate decarboxylase activity
C5P03_04145	COG1272	protein, Hemolysin III
C5P03_04150	COG2985	domain, Protein
C5P03_04150	COG0569	domain protein
C5P03_04160	COG0784	Response regulator, receiver
C5P03_04160	COG0835	chemotaxis
C5P03_04165	COG2755	lipolytic protein G-D-S-L family
C5P03_04170	COG4181	ATPase activity
C5P03_04175	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
C5P03_04180	COG1090	epimerase
C5P03_04185	COG2200	EAL domain
C5P03_04200	COG0220	tRNA (guanine-N7-)-methyltransferase activity
C5P03_04205	COG3171	Protein conserved in bacteria
C5P03_04210	COG2066	Belongs to the glutaminase family
C5P03_04215	COG2897	thiosulfate sulfurtransferase activity
C5P03_04225	COG1132	(ABC) transporter
C5P03_04240	COG1012	belongs to the aldehyde dehydrogenase family
C5P03_04270	COG4412	M6 family metalloprotease domain protein
C5P03_04270	COG3291	Pkd domain containing protein
C5P03_04275	COG3076	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome
C5P03_04280	COG5001	Diguanylate cyclase
C5P03_04280	COG3300	MHYT domain
C5P03_04300	COG4628	conserved protein (DUF2132)
C5P03_04305	COG0688	phosphatidylethanolamine metabolic process
C5P03_04315	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
C5P03_04345	COG1278	Cold shock
C5P03_04355	COG0840	transmembrane signaling receptor activity
C5P03_04360	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
C5P03_04405	COG0848	biopolymer transport protein
C5P03_04410	COG0811	peptide transport
C5P03_04415	COG0811	peptide transport
C5P03_04425	COG4206	TonB-dependent receptor
C5P03_04435	COG4239	(ABC) transporter, permease
C5P03_04440	COG0747	negative chemotaxis
C5P03_04445	COG0444	Belongs to the ABC transporter superfamily
C5P03_04450	COG4608	Belongs to the ABC transporter superfamily
C5P03_04460	COG2195	Cleaves the N-terminal amino acid of tripeptides
C5P03_04475	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
C5P03_04490	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
C5P03_04495	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
C5P03_04525	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
C5P03_04525	COG1522	sequence-specific DNA binding
C5P03_04530	COG2313	pseudouridylate synthase activity
C5P03_04540	COG1858	cytochrome C peroxidase
C5P03_04575	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
C5P03_04580	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
C5P03_04590	COG0318	PFAM AMP-dependent synthetase and ligase
C5P03_04605	COG2986	histidine ammonia-lyase
C5P03_04630	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
C5P03_04640	COG1028	Short-chain dehydrogenase reductase Sdr
C5P03_04645	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
C5P03_04655	COG0521	Mo-molybdopterin cofactor biosynthetic process
C5P03_04665	COG2966	Psort location CytoplasmicMembrane, score
C5P03_04670	COG3610	response to peptide
C5P03_04680	COG4175	Glycine betaine
C5P03_04685	COG4176	ABC-type proline glycine betaine transport system permease component
C5P03_04690	COG2113	Glycine betaine
C5P03_04695	COG0175	sulfate reduction
C5P03_04710	COG0384	phenazine biosynthesis protein PhzF
C5P03_04715	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
C5P03_04730	COG0786	glutamate:sodium symporter activity
C5P03_04735	COG0252	asparaginase activity
C5P03_04740	COG3139	Protein of unknown function (DUF1315)
C5P03_04760	COG0616	signal peptide processing
C5P03_04765	COG0446	pyridine nucleotide-disulphide oxidoreductase
C5P03_04765	COG1902	pentaerythritol trinitrate reductase activity
C5P03_04770	COG0778	Nitroreductase
C5P03_04790	COG4302	ethanolamine ammonia-lyase activity
C5P03_04795	COG4303	Ethanolamine ammonia lyase large subunit
C5P03_04805	COG2264	protein methyltransferase activity
C5P03_04810	COG0604	alcohol dehydrogenase
C5P03_04815	COG0583	DNA-binding transcription factor activity
C5P03_04820	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C5P03_04820	COG1263	PTS System
C5P03_04820	COG2190	(PTS) system
C5P03_04825	COG4145	pantothenate transmembrane transporter activity
C5P03_04830	COG3924	membrane
C5P03_04835	COG0439	Biotin carboxylase
C5P03_04840	COG0511	ligase activity, forming carbon-carbon bonds
C5P03_04845	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
C5P03_04850	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
C5P03_04880	COG3381	protein complex oligomerization
C5P03_04900	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
C5P03_04915	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
C5P03_04920	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
C5P03_04920	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
C5P03_04935	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
C5P03_04940	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
C5P03_04945	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
C5P03_04950	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
C5P03_04975	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
C5P03_04980	COG0142	geranyltranstransferase activity
C5P03_04985	COG1722	exodeoxyribonuclease VII activity
C5P03_04990	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
C5P03_05010	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
C5P03_05020	COG1534	Rna-binding protein
C5P03_05025	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
C5P03_05030	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
C5P03_05035	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
C5P03_05040	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
C5P03_05045	COG0149	triose-phosphate isomerase activity
C5P03_05050	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
C5P03_05065	COG0779	Required for maturation of 30S ribosomal subunits
C5P03_05070	COG0195	Participates in both transcription termination and antitermination
C5P03_05075	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
C5P03_05080	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
C5P03_05085	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
C5P03_05090	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
C5P03_05095	COG1185	polyribonucleotide nucleotidyltransferase activity
C5P03_05105	COG3706	GGDEF domain
C5P03_05110	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
C5P03_05115	COG1422	Protein of unknown function (DUF1090)
C5P03_05170	COG0312	modulator of DNA gyrase
C5P03_05180	COG0716	FMN binding
C5P03_05185	COG4974	Belongs to the 'phage' integrase family
C5P03_05190	COG3706	GGDEF domain
C5P03_05195	COG1970	mechanosensitive ion channel activity
C5P03_05205	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
C5P03_05220	COG3545	Serine hydrolase
C5P03_05225	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
C5P03_05270	COG4584	PFAM Integrase catalytic
C5P03_05275	COG1484	DNA-dependent DNA replication
C5P03_05315	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
C5P03_05320	COG0321	lipoyl(octanoyl) transferase activity
C5P03_05325	COG2921	Belongs to the UPF0250 family
C5P03_05330	COG1686	Belongs to the peptidase S11 family
C5P03_05335	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
C5P03_05345	COG0772	Belongs to the SEDS family
C5P03_05350	COG0768	penicillin binding
C5P03_05355	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
C5P03_05360	COG0799	negative regulation of ribosome biogenesis
C5P03_05365	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
C5P03_05385	COG0495	leucyl-tRNA aminoacylation
C5P03_05390	COG2888	peptidyl-tyrosine sulfation
C5P03_05395	COG0815	Transfers the fatty acyl group on membrane lipoproteins
C5P03_05400	COG4535	Mg2 and Co2 transporter CorC
C5P03_05405	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
C5P03_05410	COG1702	phosphate starvation-inducible protein PhoH
C5P03_05415	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
C5P03_05420	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
C5P03_05430	COG3706	GGDEF domain
C5P03_05445	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
C5P03_05465	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
C5P03_05475	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
C5P03_05485	COG0516	GMP reductase activity
C5P03_05495	COG0642	Histidine kinase
C5P03_05500	COG0745	RESPONSE REGULATOR receiver
C5P03_05535	COG3214	Protein conserved in bacteria
C5P03_05555	COG3080	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
C5P03_05560	COG3029	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
C5P03_05565	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
C5P03_05570	COG1053	succinate dehydrogenase
C5P03_05580	COG0584	glycerophosphoryl diester phosphodiesterase
C5P03_05585	COG1511	domain protein
C5P03_05585	COG3264	Mechanosensitive ion channel
C5P03_05605	COG0739	heme binding
C5P03_05620	COG0583	DNA-binding transcription factor activity
C5P03_05640	COG0583	DNA-binding transcription factor activity
C5P03_05645	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
C5P03_05675	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
C5P03_05680	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
C5P03_05690	COG0338	D12 class N6 adenine-specific DNA methyltransferase
C5P03_05695	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
C5P03_05700	COG0546	phosphoglycolate phosphatase activity
C5P03_05705	COG0180	Tryptophanyl-tRNA synthetase
C5P03_05720	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
C5P03_05730	COG1012	belongs to the aldehyde dehydrogenase family
C5P03_05740	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
C5P03_05750	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
C5P03_05750	COG0674	pyruvate-flavodoxin oxidoreductase activity
C5P03_05750	COG1013	pyruvate-flavodoxin oxidoreductase activity
C5P03_05750	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
C5P03_05760	COG0488	(ABC) transporter
C5P03_05775	COG0366	Alpha amylase catalytic
C5P03_05785	COG0443	Heat shock 70 kDa protein
C5P03_05815	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
C5P03_05825	COG0471	metal ion transport
C5P03_05825	COG0490	domain, Protein
C5P03_05895	COG0012	GTP binding
C5P03_05900	COG0193	aminoacyl-tRNA hydrolase activity
C5P03_05905	COG0737	Belongs to the 5'-nucleotidase family
C5P03_05910	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
C5P03_05920	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
C5P03_05925	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
C5P03_05930	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
C5P03_05935	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
C5P03_05940	COG2890	protein-(glutamine-N5) methyltransferase activity
C5P03_05960	COG1301	dicarboxylic acid transport
C5P03_05980	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
C5P03_05995	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
C5P03_06000	COG1115	amino acid carrier protein
C5P03_06015	COG0714	Associated with various cellular activities
C5P03_06030	COG0583	DNA-binding transcription factor activity
C5P03_06035	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
C5P03_06040	COG1678	Uncharacterized ACR, COG1678
C5P03_06050	COG0189	ligase activity
C5P03_06055	COG1385	rRNA (uridine-N3-)-methyltransferase activity
C5P03_06065	COG3091	SprT-like family
C5P03_06075	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
C5P03_06090	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
C5P03_06095	COG0739	heme binding
C5P03_06100	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
C5P03_06115	COG0463	Glycosyl transferase, family 2
C5P03_06130	COG2989	Protein conserved in bacteria
C5P03_06135	COG3108	Peptidase M15
C5P03_06145	COG2860	membrane
C5P03_06155	COG1196	nuclear chromosome segregation
C5P03_06160	COG3115	cell septum assembly
C5P03_06165	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
C5P03_06175	COG1328	CTP reductase activity
C5P03_06185	COG0602	queuosine metabolic process
C5P03_06210	COG1566	PFAM secretion protein HlyD family protein
C5P03_06215	COG1846	Transcriptional regulator
C5P03_06230	COG0281	malic enzyme
C5P03_06235	COG3290	protein histidine kinase activity
C5P03_06265	COG0346	lactoylglutathione lyase activity
C5P03_06270	COG0745	RESPONSE REGULATOR receiver
C5P03_06275	COG5002	protein histidine kinase activity
C5P03_06285	COG4783	chaperone-mediated protein folding
C5P03_06295	COG1940	carbohydrate kinase activity
C5P03_06300	COG3142	Participates in the control of copper homeostasis
C5P03_06305	COG0545	Peptidyl-prolyl cis-trans isomerase
C5P03_06310	COG1131	(ABC) transporter
C5P03_06330	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
C5P03_06350	COG0019	diaminopimelate decarboxylase activity
C5P03_06355	COG1115	amino acid carrier protein
C5P03_06360	COG0095	Lipoate-protein ligase
C5P03_06365	COG2233	PERMEase
C5P03_06370	COG0745	RESPONSE REGULATOR receiver
C5P03_06370	COG3706	GGDEF domain
C5P03_06380	COG0534	Mate efflux family protein
C5P03_06385	COG2207	Transcriptional regulator
C5P03_06390	COG0281	malic enzyme
C5P03_06395	COG2885	chlorophyll binding
C5P03_06395	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
C5P03_06420	COG0733	neurotransmitter:sodium symporter activity
C5P03_06425	COG1752	Esterase of the alpha-beta hydrolase superfamily
C5P03_06430	COG3706	GGDEF domain
C5P03_06435	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
C5P03_06440	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
C5P03_06450	COG1032	radical SAM domain protein
C5P03_06475	COG0673	inositol 2-dehydrogenase activity
C5P03_06480	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
C5P03_06485	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
C5P03_06490	COG1196	nuclear chromosome segregation
C5P03_06490	COG0741	lytic transglycosylase activity
C5P03_06490	COG0739	heme binding
C5P03_06495	COG0366	Alpha amylase catalytic
C5P03_06515	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
C5P03_06525	COG0788	formyltetrahydrofolate deformylase activity
C5P03_06530	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
C5P03_06540	COG3118	belongs to the thioredoxin family
C5P03_06545	COG2091	lysine biosynthetic process via aminoadipic acid
C5P03_06550	COG0791	NLP P60 protein
C5P03_06555	COG3129	Specifically methylates the adenine in position 1618 of 23S rRNA
C5P03_06570	COG1376	ErfK ybiS ycfS ynhG family protein
C5P03_06570	COG1388	LysM domain
C5P03_06605	COG4584	PFAM Integrase catalytic
C5P03_06610	COG1484	DNA-dependent DNA replication
C5P03_06620	COG3209	COG3209 Rhs family protein
C5P03_06655	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
C5P03_06665	COG1960	acyl-CoA dehydrogenase activity
C5P03_06670	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
C5P03_06680	COG0469	pyruvate kinase activity
C5P03_06685	COG1737	Transcriptional regulator
C5P03_06695	COG3290	protein histidine kinase activity
C5P03_06700	COG0745	RESPONSE REGULATOR receiver
C5P03_06710	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
C5P03_06730	COG1342	Belongs to the UPF0251 family
C5P03_06745	COG1574	metal-dependent hydrolase with the TIM-barrel fold
C5P03_06755	COG1677	Flagellar hook-basal body complex protein FliE
C5P03_06765	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
C5P03_06815	COG1987	bacterial-type flagellum assembly
C5P03_06820	COG1684	flagellar biosynthetic protein fliR
C5P03_06830	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
C5P03_06840	COG0455	bacterial-type flagellum organization
C5P03_06855	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
C5P03_06860	COG2198	Histidine kinase
C5P03_06860	COG0643	Histidine kinase
C5P03_06865	COG2201	protein-glutamate methylesterase activity
C5P03_06870	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
C5P03_06875	COG1360	Flagellar Motor Protein
C5P03_06880	COG1192	Involved in chromosome partitioning
C5P03_06890	COG0835	chemotaxis
C5P03_06905	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
C5P03_06910	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
C5P03_06915	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
C5P03_06920	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
C5P03_06925	COG1138	Cytochrome C-type biogenesis protein
C5P03_06930	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
C5P03_06935	COG3088	subunit of a heme lyase
C5P03_06935	COG4235	cytochrome complex assembly
C5P03_06955	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
C5P03_06960	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
C5P03_06960	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
C5P03_06975	COG0259	pyridoxamine-phosphate oxidase activity
C5P03_06980	COG0625	glutathione transferase activity
C5P03_06990	COG3153	acetyltransferase
C5P03_07010	COG2850	peptidyl-arginine hydroxylation
C5P03_07015	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
C5P03_07020	COG2915	High frequency lysogenization protein hflD homolog
C5P03_07025	COG0482	sulfurtransferase activity
C5P03_07045	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
C5P03_07055	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
C5P03_07055	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
C5P03_07055	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
C5P03_07085	COG0159	tryptophan synthase activity
C5P03_07090	COG0133	tryptophan synthase activity
C5P03_07095	COG0134	indole-3-glycerol-phosphate synthase activity
C5P03_07095	COG0135	phosphoribosylanthranilate isomerase activity
C5P03_07100	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
C5P03_07105	COG0512	Glutamine amidotransferase of anthranilate synthase
C5P03_07105	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
C5P03_07110	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
C5P03_07115	COG0613	PHP domain protein
C5P03_07120	COG0009	L-threonylcarbamoyladenylate synthase
C5P03_07130	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
C5P03_07140	COG1946	Acyl-CoA thioesterase
C5P03_07155	COG1309	transcriptional regulator
C5P03_07160	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
C5P03_07165	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
C5P03_07170	COG1538	Outer membrane efflux protein
C5P03_07185	COG1091	dTDP-4-dehydrorhamnose reductase activity
C5P03_07205	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
C5P03_07210	COG1459	type II secretion system
C5P03_07245	COG1450	Type ii and iii secretion system protein
C5P03_07265	COG0438	transferase activity, transferring glycosyl groups
C5P03_07270	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
C5P03_07290	COG0471	metal ion transport
C5P03_07290	COG3273	potassium ion transport
C5P03_07295	COG0490	domain, Protein
C5P03_07295	COG0471	metal ion transport
C5P03_07315	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
C5P03_07345	COG0438	transferase activity, transferring glycosyl groups
C5P03_07355	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
C5P03_07365	COG3132	Protein of unknown function, DUF480
C5P03_07380	COG4584	PFAM Integrase catalytic
C5P03_07385	COG1484	DNA-dependent DNA replication
C5P03_07425	COG1278	Cold shock
C5P03_07470	COG1187	pseudouridine synthase activity
C5P03_07480	COG4166	transmembrane transport
C5P03_07485	COG0622	Phosphoesterase
C5P03_07505	COG0835	chemotaxis
C5P03_07505	COG0784	Response regulator, receiver
C5P03_07510	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
C5P03_07515	COG1815	bacterial-type flagellum-dependent cell motility
C5P03_07520	COG1558	bacterial-type flagellum-dependent cell motility
C5P03_07535	COG4787	bacterial-type flagellum-dependent cell motility
C5P03_07540	COG4786	Flagellar basal body rod
C5P03_07545	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
C5P03_07550	COG1706	bacterial-type flagellum-dependent cell motility
C5P03_07570	COG2239	Acts as a magnesium transporter
C5P03_07575	COG0248	Ppx GppA phosphatase
C5P03_07580	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
C5P03_07600	COG3852	Histidine kinase
C5P03_07605	COG2204	response regulator
C5P03_07610	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
C5P03_07615	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
C5P03_07620	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
C5P03_07625	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
C5P03_07645	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
C5P03_07655	COG0590	tRNA wobble adenosine to inosine editing
C5P03_07660	COG0573	inorganic phosphate transmembrane transporter activity
C5P03_07665	COG0581	inorganic phosphate transmembrane transporter activity
C5P03_07675	COG0704	Plays a role in the regulation of phosphate uptake
C5P03_07680	COG1253	flavin adenine dinucleotide binding
C5P03_07695	COG0531	amino acid
C5P03_07705	COG1126	abc transporter atp-binding protein
C5P03_07710	COG0765	amino acid transport
C5P03_07715	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C5P03_07720	COG3706	GGDEF domain
C5P03_07725	COG2271	Major facilitator Superfamily
C5P03_07740	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
C5P03_07760	COG1785	Belongs to the alkaline phosphatase family
C5P03_07765	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
C5P03_07770	COG0123	including yeast histone deacetylase and acetoin utilization protein
C5P03_07780	COG1199	ATP-dependent helicase activity
C5P03_07785	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
C5P03_07795	COG1448	Aminotransferase
C5P03_07800	COG0433	COG0433 Predicted ATPase
C5P03_07815	COG0658	competence protein
C5P03_07815	COG2333	competence protein COMEC
C5P03_07820	COG1132	(ABC) transporter
C5P03_07825	COG1663	tetraacyldisaccharide 4'-kinase activity
C5P03_07830	COG2835	tetraacyldisaccharide 4'-kinase activity
C5P03_07835	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
C5P03_07840	COG2197	response regulator
C5P03_07845	COG0322	excinuclease ABC activity
C5P03_07870	COG4737	Cytotoxic translational repressor of toxin-antitoxin stability system
C5P03_08010	COG4695	Portal protein
C5P03_08065	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
C5P03_08075	COG4974	Belongs to the 'phage' integrase family
C5P03_08105	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
C5P03_08115	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
C5P03_08180	COG2119	membrane
C5P03_08185	COG0023	Translation Initiation Factor
C5P03_08225	COG2205	protein histidine kinase activity
C5P03_08225	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C5P03_08235	COG4138	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system
C5P03_08240	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
C5P03_08245	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
C5P03_08250	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
C5P03_08255	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
C5P03_08260	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
C5P03_08275	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
C5P03_08280	COG0505	Belongs to the CarA family
C5P03_08285	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
C5P03_08290	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
C5P03_08325	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
C5P03_08330	COG0513	Belongs to the DEAD box helicase family
C5P03_08355	COG0789	Transcriptional regulator
C5P03_08370	COG0493	'glutamate synthase
C5P03_08375	COG0070	glutamate synthase
C5P03_08375	COG0069	glutamate synthase activity
C5P03_08375	COG0067	glutamate synthase
C5P03_08380	COG1242	4 iron, 4 sulfur cluster binding
C5P03_08450	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
C5P03_08455	COG1288	antiporter activity
C5P03_08460	COG0436	Aminotransferase
C5P03_08470	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
C5P03_08475	COG2027	D-alanyl-D-alanine carboxypeptidase
C5P03_08480	COG1061	Type III restriction enzyme res subunit
C5P03_08485	COG1566	PFAM secretion protein HlyD family protein
C5P03_08495	COG1966	Carbon starvation protein
C5P03_08500	COG3279	Response regulator of the LytR AlgR family
C5P03_08505	COG3275	phosphorelay sensor kinase activity
C5P03_08515	COG1012	belongs to the aldehyde dehydrogenase family
C5P03_08515	COG1454	alcohol dehydrogenase
C5P03_08525	COG2095	MarC family integral membrane protein
C5P03_08535	COG0601	transmembrane transport
C5P03_08540	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
C5P03_08545	COG0444	Belongs to the ABC transporter superfamily
C5P03_08560	COG0861	Integral membrane protein TerC family
C5P03_08565	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
C5P03_08575	COG1301	dicarboxylic acid transport
C5P03_08590	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
C5P03_08605	COG0537	adenosine 5'-monophosphoramidase activity
C5P03_08640	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
C5P03_08645	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
C5P03_08665	COG1007	ATP synthesis coupled electron transport
C5P03_08670	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
C5P03_08680	COG0713	ATP synthesis coupled electron transport
C5P03_08685	COG0839	Belongs to the complex I subunit 6 family
C5P03_08690	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
C5P03_08695	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
C5P03_08700	COG1034	ATP synthesis coupled electron transport
C5P03_08715	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
C5P03_08715	COG0649	NAD binding
C5P03_08720	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
C5P03_08725	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
C5P03_08730	COG1360	Flagellar Motor Protein
C5P03_08735	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
C5P03_08750	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
C5P03_08765	COG4597	amino acid ABC transporter
C5P03_08770	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C5P03_08775	COG0765	amino acid transport
C5P03_08780	COG1126	abc transporter atp-binding protein
C5P03_08790	COG0724	RNA recognition motif
C5P03_08795	COG4989	oxidoreductase activity
C5P03_08820	COG3437	response regulator, receiver
C5P03_08825	COG0583	DNA-binding transcription factor activity
C5P03_08860	COG2814	Major facilitator Superfamily
C5P03_08865	COG0583	DNA-binding transcription factor activity
C5P03_08875	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
C5P03_08880	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
C5P03_08885	COG0539	negative regulation of cytoplasmic translation
C5P03_08890	COG0776	regulation of translation
C5P03_08900	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
C5P03_08905	COG0284	orotidine-5'-phosphate decarboxylase activity
C5P03_08920	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
C5P03_08925	COG0602	queuosine metabolic process
C5P03_08930	COG3530	Putative quorum-sensing-regulated virulence factor
C5P03_08935	COG2096	Adenosyltransferase
C5P03_08940	COG2916	Histone family protein nucleoid-structuring protein H-NS
C5P03_08950	COG1757	Na H antiporter
C5P03_08955	COG1435	thymidine kinase activity
C5P03_08980	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
C5P03_08985	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
C5P03_08990	COG0437	4 iron, 4 sulfur cluster binding
C5P03_08995	COG5557	Pfam Polysulphide reductase, NrfD
C5P03_09000	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
C5P03_09005	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
C5P03_09010	COG1773	rubredoxin
C5P03_09020	COG0601	transmembrane transport
C5P03_09025	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
C5P03_09040	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
C5P03_09045	COG0375	protein maturation
C5P03_09050	COG0309	Hydrogenase expression formation protein (HypE)
C5P03_09060	COG0298	carbon dioxide binding
C5P03_09065	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
C5P03_09075	COG1921	L-seryl-tRNASec selenium transferase activity
C5P03_09080	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
C5P03_09090	COG3260	NADH ubiquinone oxidoreductase 20
C5P03_09095	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
C5P03_09100	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
C5P03_09100	COG3261	NADH dehydrogenase
C5P03_09105	COG0650	Formate hydrogenlyase subunit 4
C5P03_09110	COG0651	ATP synthesis coupled electron transport
C5P03_09115	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
C5P03_09120	COG3158	transport of potassium into the cell
C5P03_09140	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
C5P03_09165	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
C5P03_09170	COG0326	Molecular chaperone. Has ATPase activity
C5P03_09180	COG0563	adenylate kinase activity
C5P03_09185	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
C5P03_09190	COG3788	relative of glutathione S-transferase, MAPEG superfamily
C5P03_09195	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
C5P03_09200	COG0840	transmembrane signaling receptor activity
C5P03_09215	COG3300	MHYT domain
C5P03_09215	COG5001	Diguanylate cyclase
C5P03_09220	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
C5P03_09240	COG1021	2,3-dihydroxybenzoate-AMP ligase
C5P03_09245	COG3433	isochorismatase activity
C5P03_09245	COG1535	isochorismatase
C5P03_09250	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
C5P03_09255	COG1028	Short-chain dehydrogenase reductase Sdr
C5P03_09265	COG0300	oxidoreductase activity
C5P03_09265	COG0318	PFAM AMP-dependent synthetase and ligase
C5P03_09265	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
C5P03_09265	COG1028	Short-chain dehydrogenase reductase Sdr
C5P03_09265	COG3321	synthase
C5P03_09270	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
C5P03_09275	COG2977	Belongs to the P-Pant transferase superfamily
C5P03_09280	COG1120	ATPase activity
C5P03_09285	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C5P03_09290	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C5P03_09295	COG4771	TonB-dependent receptor
C5P03_09315	COG0598	Magnesium transport protein CorA
C5P03_09320	COG0644	oxidoreductase
C5P03_09320	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
C5P03_09340	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
C5P03_09345	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
C5P03_09350	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
C5P03_09365	COG1570	exodeoxyribonuclease VII activity
C5P03_09370	COG3038	cytochrome b561
C5P03_09390	COG0516	GMP reductase activity
C5P03_09390	COG0517	IMP dehydrogenase activity
C5P03_09395	COG0519	Catalyzes the synthesis of GMP from XMP
C5P03_09395	COG0518	GMP synthase (glutamine-hydrolyzing) activity
C5P03_09430	COG1025	Belongs to the peptidase M16 family
C5P03_09435	COG2062	phosphohistidine phosphatase, SixA
C5P03_09445	COG0697	spore germination
C5P03_09450	COG4166	transmembrane transport
C5P03_09455	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
C5P03_09460	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
C5P03_09470	COG4591	ABC-type transport system involved in lipoprotein release permease component
C5P03_09475	COG1136	(ABC) transporter
C5P03_09480	COG4591	ABC-type transport system involved in lipoprotein release permease component
C5P03_09485	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
C5P03_09500	COG0544	peptidyl-prolyl cis-trans isomerase activity
C5P03_09505	COG0740	serine-type endopeptidase activity
C5P03_09510	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
C5P03_09515	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
C5P03_09520	COG0776	regulation of translation
C5P03_09525	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
C5P03_09530	COG0488	(ABC) transporter
C5P03_09535	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
C5P03_09540	COG3162	membrane
C5P03_09555	COG1024	Enoyl-CoA hydratase
C5P03_09555	COG1250	3-hydroxyacyl-CoA dehydrogenase
C5P03_09560	COG1115	amino acid carrier protein
C5P03_09565	COG0456	acetyltransferase
C5P03_09575	COG1584	GPR1 FUN34 yaaH family protein
C5P03_09605	COG1024	Enoyl-CoA hydratase
C5P03_09610	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
C5P03_09615	COG1960	acyl-CoA dehydrogenase activity
C5P03_09625	COG1960	acyl-CoA dehydrogenase activity
C5P03_09630	COG1024	Enoyl-CoA hydratase
C5P03_09635	COG1024	Enoyl-CoA hydratase
C5P03_09645	COG1028	Short-chain dehydrogenase reductase Sdr
C5P03_09655	COG0730	response to heat
C5P03_09700	COG3706	GGDEF domain
C5P03_09705	COG2840	Smr protein MutS2
C5P03_09710	COG2890	protein-(glutamine-N5) methyltransferase activity
C5P03_09715	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
C5P03_09725	COG0513	Belongs to the DEAD box helicase family
C5P03_09730	COG5654	RES domain protein
C5P03_09740	COG0814	amino acid
C5P03_09745	COG1609	Transcriptional regulator
C5P03_09750	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
C5P03_09750	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
C5P03_09755	COG1105	Belongs to the carbohydrate kinase PfkB family
C5P03_09760	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
C5P03_09760	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
C5P03_09760	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
C5P03_09765	COG3313	Fe-S protein
C5P03_09770	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
C5P03_09775	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
C5P03_09780	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
C5P03_09785	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
C5P03_09795	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
C5P03_09815	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
C5P03_09820	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
C5P03_09825	COG0291	Belongs to the bacterial ribosomal protein bL35 family
C5P03_09830	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
C5P03_09835	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
C5P03_09840	COG0072	phenylalanine-tRNA ligase activity
C5P03_09840	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
C5P03_09845	COG0776	regulation of translation
C5P03_09865	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
C5P03_09875	COG2199	diguanylate cyclase activity
C5P03_09880	COG1609	Transcriptional regulator
C5P03_09885	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
C5P03_09890	COG1879	ABC-type sugar transport system periplasmic component
C5P03_09895	COG1172	Belongs to the binding-protein-dependent transport system permease family
C5P03_09905	COG1869	D-ribose catabolic process
C5P03_09910	COG0625	glutathione transferase activity
C5P03_09925	COG0037	tRNA processing
C5P03_09930	COG0589	response to stress
C5P03_09935	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
C5P03_09950	COG2217	Heavy metal translocating P-type atpase
C5P03_09960	COG2010	Cytochrome c
C5P03_09975	COG3278	Belongs to the heme-copper respiratory oxidase family
C5P03_09985	COG1956	GAF domain-containing protein
C5P03_09990	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
C5P03_10000	COG0308	aminopeptidase N
C5P03_10010	COG2902	Dehydrogenase
C5P03_10015	COG0167	dihydroorotate dehydrogenase activity
C5P03_10025	COG0116	Belongs to the methyltransferase superfamily
C5P03_10025	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
C5P03_10050	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
C5P03_10055	COG1067	ATP-dependent peptidase activity
C5P03_10065	COG4128	Pfam Zonular occludens toxin
C5P03_10120	COG1484	DNA-dependent DNA replication
C5P03_10125	COG4584	PFAM Integrase catalytic
C5P03_10130	COG4128	Pfam Zonular occludens toxin
C5P03_10200	COG4221	oxidoreductase activity
C5P03_10250	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
C5P03_10260	COG2995	paraquat-inducible protein a
C5P03_10270	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
C5P03_10270	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
C5P03_10285	COG0084	hydrolase, TatD family'
C5P03_10290	COG0470	DNA polymerase III
C5P03_10295	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
C5P03_10300	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
C5P03_10305	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
C5P03_10310	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
C5P03_10315	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
C5P03_10320	COG1028	Short-chain dehydrogenase reductase Sdr
C5P03_10330	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
C5P03_10335	COG0416	fatty acid biosynthetic process
C5P03_10340	COG0333	Belongs to the bacterial ribosomal protein bL32 family
C5P03_10345	COG1399	metal-binding, possibly nucleic acid-binding protein
C5P03_10350	COG0424	maF-like protein
C5P03_10355	COG0546	phosphoglycolate phosphatase activity
C5P03_10365	COG1530	ribonuclease E activity
C5P03_10375	COG0306	phosphate transporter
C5P03_10380	COG0717	Belongs to the dCTP deaminase family
C5P03_10385	COG0572	uridine kinase
C5P03_10390	COG0489	protein tyrosine kinase activity
C5P03_10395	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
C5P03_10395	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
C5P03_10405	COG1254	Belongs to the acylphosphatase family
C5P03_10415	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
C5P03_10430	COG0709	Synthesizes selenophosphate from selenide and ATP
C5P03_10435	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
C5P03_10440	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
C5P03_10445	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
C5P03_10455	COG1643	Atp-dependent helicase
C5P03_10465	COG2197	response regulator
C5P03_10475	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
C5P03_10480	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
C5P03_10485	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
C5P03_10490	COG2832	Protein of unknown function (DUF454)
C5P03_10495	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
C5P03_10515	COG0318	PFAM AMP-dependent synthetase and ligase
C5P03_10520	COG2267	carboxylic ester hydrolase activity
C5P03_10530	COG1214	PFAM Peptidase M22, glycoprotease
C5P03_10535	COG1199	ATP-dependent helicase activity
C5P03_10545	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
C5P03_10550	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
C5P03_10555	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
C5P03_10560	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
C5P03_10560	COG0131	Imidazoleglycerol-phosphate dehydratase
C5P03_10565	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
C5P03_10570	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
C5P03_10575	COG3437	response regulator, receiver
C5P03_10585	COG2205	protein histidine kinase activity
C5P03_10585	COG2198	Histidine kinase
C5P03_10585	COG0784	Response regulator, receiver
C5P03_10590	COG0107	imidazoleglycerol-phosphate synthase activity
C5P03_10595	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
C5P03_10595	COG0140	phosphoribosyl-ATP diphosphatase activity
C5P03_10605	COG2378	regulation of single-species biofilm formation
C5P03_10665	COG2823	Periplasmic or secreted lipoprotein
C5P03_10670	COG3706	GGDEF domain
C5P03_10670	COG2203	Gaf domain
C5P03_10670	COG4251	negative regulation of phosphorylation
C5P03_10670	COG5001	Diguanylate cyclase
C5P03_10675	COG1172	Belongs to the binding-protein-dependent transport system permease family
C5P03_10685	COG1129	ABC transporter
C5P03_10690	COG1879	ABC-type sugar transport system periplasmic component
C5P03_10715	COG2824	Alkylphosphonate utilization operon protein PhnA
C5P03_10720	COG1250	3-hydroxyacyl-CoA dehydrogenase
C5P03_10720	COG1024	Enoyl-CoA hydratase
C5P03_10725	COG0183	Belongs to the thiolase family
C5P03_10730	COG0714	Associated with various cellular activities
C5P03_10770	COG2067	long-chain fatty acid transport protein
C5P03_10775	COG2067	long-chain fatty acid transport protein
C5P03_10780	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
C5P03_10800	COG3123	guanosine phosphorylase activity
C5P03_10805	COG1760	l-serine dehydratase
C5P03_10815	COG1760	l-serine dehydratase
C5P03_10820	COG2951	lytic endotransglycosylase activity
C5P03_10825	COG3100	YcgL domain-containing protein
C5P03_10830	COG0850	regulation of cytokinetic process
C5P03_10835	COG2894	cell division
C5P03_10840	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
C5P03_10850	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
C5P03_10890	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
C5P03_10895	COG0697	spore germination
C5P03_10900	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
C5P03_10905	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
C5P03_10915	COG0307	riboflavin synthase, alpha
C5P03_10925	COG0534	Mate efflux family protein
C5P03_10950	COG0417	DNA replication proofreading
C5P03_10975	COG1560	Kdo2-lipid A biosynthetic process
C5P03_10980	COG1560	Kdo2-lipid A biosynthetic process
C5P03_10990	COG0583	DNA-binding transcription factor activity
C5P03_10995	COG0673	inositol 2-dehydrogenase activity
C5P03_11000	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
C5P03_11005	COG0583	DNA-binding transcription factor activity
C5P03_11010	COG1028	Short-chain dehydrogenase reductase Sdr
C5P03_11030	COG3134	Outer membrane lipoprotein
C5P03_11050	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C5P03_11070	COG4681	YaeQ
C5P03_11140	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
C5P03_11145	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
C5P03_11150	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
C5P03_11160	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
C5P03_11165	COG1434	Gram-negative-bacterium-type cell wall biogenesis
C5P03_11175	COG0205	6-phosphofructokinase activity
C5P03_11220	COG1011	Hydrolase
C5P03_11225	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
C5P03_11280	COG3593	DNA synthesis involved in DNA repair
C5P03_11295	COG0583	DNA-binding transcription factor activity
C5P03_11300	COG0730	response to heat
C5P03_11315	COG1181	Belongs to the D-alanine--D-alanine ligase family
C5P03_11325	COG0386	Belongs to the glutathione peroxidase family
C5P03_11330	COG0513	Belongs to the DEAD box helicase family
C5P03_11345	COG1742	UPF0060 membrane protein
C5P03_11380	COG2329	Antibiotic biosynthesis monooxygenase
C5P03_11385	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
C5P03_11405	COG3243	poly(R)-hydroxyalkanoic acid synthase
C5P03_11415	COG2501	S4 domain
C5P03_11425	COG1132	(ABC) transporter
C5P03_11440	COG3118	belongs to the thioredoxin family
C5P03_11445	COG0471	metal ion transport
C5P03_11450	COG0058	SHG alpha-glucan phosphorylase activity
C5P03_11480	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
C5P03_11490	COG0814	amino acid
C5P03_11495	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
C5P03_11500	COG0514	ATP-dependent DNA helicase (RecQ)
C5P03_11505	COG2766	serine protein kinase
C5P03_11515	COG2719	SpoVR family
C5P03_11520	COG2186	Transcriptional regulator
C5P03_11525	COG3067	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
C5P03_11530	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
C5P03_11535	COG0586	Pfam SNARE associated Golgi protein
C5P03_11545	COG0556	nucleotide-excision repair
C5P03_11560	COG2985	domain, Protein
C5P03_11560	COG0569	domain protein
C5P03_11565	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
C5P03_11585	COG4565	transcriptional regulatory protein
C5P03_11590	COG3290	protein histidine kinase activity
C5P03_11595	COG1940	carbohydrate kinase activity
C5P03_11595	COG1846	Transcriptional regulator
C5P03_11600	COG0840	transmembrane signaling receptor activity
C5P03_11605	COG3012	SEC-C Motif Domain Protein
C5P03_11610	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
C5P03_11615	COG3075	Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses fumarate or nitrate as electron acceptor
C5P03_11620	COG0247	lactate metabolic process
C5P03_11630	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
C5P03_11635	COG0437	4 iron, 4 sulfur cluster binding
C5P03_11640	COG3301	Polysulphide reductase, NrfD
C5P03_11655	COG3088	subunit of a heme lyase
C5P03_11655	COG4235	cytochrome complex assembly
C5P03_11670	COG3033	Beta-eliminating lyase
C5P03_11680	COG3046	protein related to deoxyribodipyrimidine photolyase
C5P03_11685	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
C5P03_11710	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
C5P03_11715	COG0583	DNA-binding transcription factor activity
C5P03_11725	COG4774	siderophore transport
C5P03_11730	COG3708	Transcriptional regulator
C5P03_11730	COG2207	Transcriptional regulator
C5P03_11740	COG0583	DNA-binding transcription factor activity
C5P03_11745	COG2910	NAD(P)H-binding
C5P03_11760	COG0612	Peptidase, M16
C5P03_11765	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
C5P03_11770	COG1944	ATP diphosphatase activity
C5P03_11775	COG2116	formate transmembrane transporter activity
C5P03_11780	COG1882	Formate acetyltransferase
C5P03_11790	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
C5P03_11795	COG0045	succinate-CoA ligase (ADP-forming) activity
C5P03_11800	COG0508	dehydrogenase complex catalyzes the overall conversion of
C5P03_11805	COG0567	Dehydrogenase, E1 component
C5P03_11815	COG1053	succinate dehydrogenase
C5P03_11820	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
C5P03_11825	COG2009	succinate dehydrogenase
C5P03_11845	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
C5P03_11850	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
C5P03_11850	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
C5P03_11860	COG3069	C4-dicarboxylate transmembrane transporter activity
C5P03_11875	COG1451	nucleotide metabolic process
C5P03_11890	COG0254	rRNA binding
C5P03_11895	COG0257	Belongs to the bacterial ribosomal protein bL36 family
C5P03_11900	COG0469	pyruvate kinase activity
C5P03_11910	COG1874	Beta-galactosidase
C5P03_11915	COG3867	Arabinogalactan endo-beta-1,4-galactanase
C5P03_11920	COG3833	ABC-type maltose transport systems, permease component
C5P03_11925	COG1175	transmembrane transport
C5P03_11930	COG2182	Extracellular solute-binding protein
C5P03_11970	COG4580	involved in the transport of maltose and maltodextrins
C5P03_11980	COG1609	Transcriptional regulator
C5P03_11985	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
C5P03_11990	COG1085	galactose-1-phosphate uridylyltransferase
C5P03_11995	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
C5P03_12005	COG1172	Belongs to the binding-protein-dependent transport system permease family
C5P03_12010	COG1129	ABC transporter
C5P03_12015	COG1879	ABC-type sugar transport system periplasmic component
C5P03_12020	COG1069	ribulokinase activity
C5P03_12030	COG2160	L-arabinose isomerase activity
C5P03_12035	COG0583	DNA-binding transcription factor activity
C5P03_12045	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
C5P03_12060	COG2925	Exonuclease
C5P03_12075	COG1380	Effector of murein hydrolase LrgA
C5P03_12080	COG1346	cytolysis
C5P03_12085	COG0295	cytidine deaminase activity
C5P03_12090	COG1022	Amp-dependent synthetase and ligase
C5P03_12105	COG0861	Integral membrane protein TerC family
C5P03_12115	COG2199	diguanylate cyclase activity
C5P03_12130	COG2154	pterin-4-alpha-carbinolamine dehydratase
C5P03_12140	COG3768	UPF0283 membrane protein
C5P03_12145	COG3106	COG3106 Predicted ATPase
C5P03_12160	COG1842	Phage shock protein A
C5P03_12165	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
C5P03_12175	COG4168	peptide transport system, permease
C5P03_12180	COG4171	peptide transport system, permease
C5P03_12185	COG4172	Belongs to the ABC transporter superfamily
C5P03_12190	COG4172	Belongs to the ABC transporter superfamily
C5P03_12200	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
C5P03_12205	COG1286	toxin biosynthetic process
C5P03_12210	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
C5P03_12215	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
C5P03_12220	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
C5P03_12225	COG0531	amino acid
C5P03_12225	COG1674	ftsk spoiiie
C5P03_12240	COG0492	ferredoxin-NADP+ reductase activity
C5P03_12245	COG3706	GGDEF domain
C5P03_12250	COG3134	Outer membrane lipoprotein
C5P03_12255	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
C5P03_12260	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
C5P03_12265	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
C5P03_12270	COG0542	response to heat
C5P03_12275	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
C5P03_12280	COG1278	Cold shock
C5P03_12285	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
C5P03_12420	COG0659	secondary active sulfate transmembrane transporter activity
C5P03_12460	COG0697	spore germination
C5P03_12465	COG4657	Part of a membrane complex involved in electron transport
C5P03_12470	COG2878	Part of a membrane complex involved in electron transport
C5P03_12480	COG4658	electron transport chain
C5P03_12485	COG4659	FMN binding
C5P03_12495	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
C5P03_12500	COG0346	lactoylglutathione lyase activity
C5P03_12515	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
C5P03_12520	COG2056	Na+-H+ antiporter family
C5P03_12525	COG5001	Diguanylate cyclase
C5P03_12525	COG3300	MHYT domain
C5P03_12535	COG0513	Belongs to the DEAD box helicase family
C5P03_12540	COG2050	protein possibly involved in aromatic compounds catabolism
C5P03_12550	COG0247	lactate metabolic process
C5P03_12550	COG0277	FAD linked oxidase domain protein
C5P03_12560	COG1253	flavin adenine dinucleotide binding
C5P03_12565	COG1902	pentaerythritol trinitrate reductase activity
C5P03_12570	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
C5P03_12575	COG0647	UMP catabolic process
C5P03_12580	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
C5P03_12580	COG4651	solute:proton antiporter activity
C5P03_12590	COG0367	asparagine synthase
C5P03_12610	COG0625	glutathione transferase activity
C5P03_12615	COG0625	glutathione transferase activity
C5P03_12640	COG0564	pseudouridine synthase activity
C5P03_12650	COG0840	transmembrane signaling receptor activity
C5P03_12660	COG0670	Belongs to the BI1 family
C5P03_12665	COG1289	transmembrane transporter activity
C5P03_12670	COG2920	part of a sulfur-relay system
C5P03_12675	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
C5P03_12680	COG0285	dihydrofolate synthase activity
C5P03_12685	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
C5P03_12690	COG0101	tRNA pseudouridine synthase activity
C5P03_12700	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
C5P03_12705	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
C5P03_12710	COG0671	phosphoesterase, PA-phosphatase related
C5P03_12715	COG1464	Belongs to the NlpA lipoprotein family
C5P03_12755	COG0574	Belongs to the PEP-utilizing enzyme family
C5P03_12755	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
C5P03_12760	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
C5P03_12800	COG0672	)-iron permease
C5P03_12860	COG1285	pathogenesis
C5P03_12905	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
C5P03_12910	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
C5P03_12910	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
C5P03_12915	COG0527	aspartate kinase activity
C5P03_12925	COG1368	sulfuric ester hydrolase activity
C5P03_12930	COG1619	proteins homologs of microcin C7 resistance protein MccF
C5P03_12940	COG0393	Putative heavy-metal-binding
C5P03_12945	COG1252	NADH dehydrogenase
C5P03_12965	COG2354	Protein conserved in bacteria
C5P03_12975	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
C5P03_12975	COG0047	phosphoribosylformylglycinamidine synthase activity
C5P03_12980	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
C5P03_12985	COG1645	bacterial-type flagellum-dependent swarming motility
C5P03_12990	COG1160	GTP binding
C5P03_12995	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
C5P03_13000	COG2976	Protein conserved in bacteria
C5P03_13005	COG0124	histidyl-tRNA synthetase
C5P03_13010	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
C5P03_13015	COG1426	Protein conserved in bacteria
C5P03_13025	COG0820	rRNA (adenine-C2-)-methyltransferase activity
C5P03_13030	COG0105	UTP biosynthetic process
C5P03_13035	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
C5P03_13045	COG0633	Ferredoxin
C5P03_13050	COG0443	Heat shock 70 kDa protein
C5P03_13055	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
C5P03_13065	COG0822	iron-sulfur transferase activity
C5P03_13070	COG1104	cysteine desulfurase activity
C5P03_13110	COG2897	thiosulfate sulfurtransferase activity
C5P03_13115	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
C5P03_13120	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
C5P03_13125	COG1862	Preprotein translocase
C5P03_13130	COG0343	queuine tRNA-ribosyltransferase activity
C5P03_13135	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
C5P03_13140	COG0517	IMP dehydrogenase activity
C5P03_13145	COG0450	alkyl hydroperoxide reductase
C5P03_13150	COG3634	alkyl hydroperoxide reductase activity
C5P03_13165	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
C5P03_13165	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
C5P03_13170	COG0509	glycine decarboxylation via glycine cleavage system
C5P03_13175	COG0404	The glycine cleavage system catalyzes the degradation of glycine
C5P03_13180	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
C5P03_13185	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
C5P03_13210	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
C5P03_13215	COG0583	DNA-binding transcription factor activity
C5P03_13220	COG2814	Major facilitator Superfamily
C5P03_13225	COG0444	Belongs to the ABC transporter superfamily
C5P03_13230	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
C5P03_13235	COG0601	transmembrane transport
C5P03_13245	COG0625	glutathione transferase activity
C5P03_13255	COG0483	inositol monophosphate 1-phosphatase activity
C5P03_13275	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
C5P03_13285	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
C5P03_13315	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
C5P03_13320	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
C5P03_13335	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
C5P03_13335	COG0301	tRNA thio-modification
C5P03_13590	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
C5P03_13625	COG2974	May be involved in recombination
C5P03_13675	COG0582	viral genome integration into host DNA
C5P03_13685	COG4953	penicillin-binding protein 1C
C5P03_13690	COG2373	Large extracellular alpha-helical protein
C5P03_13705	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
C5P03_13725	COG4215	(ABC) transporter
C5P03_13740	COG2431	L-lysine efflux transmembrane transporter activity
C5P03_13745	COG3124	Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP
C5P03_13755	COG1393	Belongs to the ArsC family
C5P03_13765	COG4783	chaperone-mediated protein folding
C5P03_13770	COG0425	Belongs to the sulfur carrier protein TusA family
C5P03_13775	COG0628	permease
C5P03_13790	COG3842	ATPase activity
C5P03_13800	COG1175	transmembrane transport
C5P03_13805	COG2182	Extracellular solute-binding protein
C5P03_13810	COG3081	Nucleoid-associated protein
C5P03_13815	COG3082	Protein of unknown function (DUF1414)
C5P03_13820	COG3083	sulfuric ester hydrolase activity
C5P03_13825	COG4771	TonB-dependent receptor
C5P03_13830	COG1770	oligopeptidase
C5P03_13850	COG4574	serine-type endopeptidase inhibitor activity
C5P03_13855	COG3085	chromosome segregation
C5P03_13865	COG1605	Chorismate mutase
C5P03_13865	COG0287	Prephenate dehydrogenase
C5P03_13870	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
C5P03_13875	COG0584	glycerophosphoryl diester phosphodiesterase
C5P03_13880	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
C5P03_13890	COG1349	DNA-binding transcription factor activity
C5P03_13895	COG2271	Major facilitator Superfamily
C5P03_13900	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
C5P03_13905	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
C5P03_13910	COG0583	DNA-binding transcription factor activity
C5P03_13935	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
C5P03_13940	COG0656	L-ascorbic acid biosynthetic process
C5P03_13945	COG2814	Major facilitator Superfamily
C5P03_13955	COG1294	oxidase, subunit
C5P03_13965	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
C5P03_13970	COG2979	Protein of unknown function (DUF533)
C5P03_13990	COG0583	DNA-binding transcription factor activity
C5P03_14000	COG2807	transmembrane transport
C5P03_14005	COG1187	pseudouridine synthase activity
C5P03_14010	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
C5P03_14020	COG0346	lactoylglutathione lyase activity
C5P03_14050	COG1166	arginine decarboxylase activity
C5P03_14060	COG2195	Cleaves the N-terminal amino acid of tripeptides
C5P03_14085	COG2353	YceI-like domain
C5P03_14090	COG0583	DNA-binding transcription factor activity
C5P03_14100	COG2759	Belongs to the formate--tetrahydrofolate ligase family
C5P03_14105	COG0840	transmembrane signaling receptor activity
C5P03_14110	COG0302	gtp cyclohydrolase
C5P03_14120	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
C5P03_14150	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
C5P03_14165	COG0314	molybdopterin synthase activity
C5P03_14170	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
C5P03_14175	COG0315	cyclic pyranopterin monophosphate synthase activity
C5P03_14180	COG0521	Mo-molybdopterin cofactor biosynthetic process
C5P03_14185	COG3005	denitrification pathway
C5P03_14195	COG0348	domain, Protein
C5P03_14200	COG0437	4 iron, 4 sulfur cluster binding
C5P03_14205	COG0243	molybdopterin cofactor binding
C5P03_14215	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
C5P03_14220	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
C5P03_14225	COG3850	Histidine kinase
C5P03_14230	COG2197	response regulator
C5P03_14240	COG0784	Response regulator, receiver
C5P03_14240	COG2205	protein histidine kinase activity
C5P03_14260	COG0121	glutamine amidotransferase
C5P03_14265	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
C5P03_14270	COG1960	acyl-CoA dehydrogenase activity
C5P03_14275	COG3437	response regulator, receiver
C5P03_14275	COG0784	Response regulator, receiver
C5P03_14285	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
C5P03_14290	COG0328	RNA-DNA hybrid ribonuclease activity
C5P03_14295	COG2226	methyltransferase
C5P03_14300	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
C5P03_14305	COG1388	LysM domain
C5P03_14305	COG0741	lytic transglycosylase activity
C5P03_14310	COG3021	interspecies interaction between organisms
C5P03_14320	COG1607	acyl-coa hydrolase
C5P03_14345	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
C5P03_14360	COG2911	Protein conserved in bacteria
C5P03_14365	COG0729	surface antigen
C5P03_14380	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
C5P03_14385	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
C5P03_14395	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
C5P03_14405	COG4134	Bacterial extracellular solute-binding protein
C5P03_14410	COG4135	transport system, permease component
C5P03_14415	COG4136	ATPase activity
C5P03_14420	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
C5P03_14425	COG2951	lytic endotransglycosylase activity
C5P03_14430	COG1846	Transcriptional regulator
C5P03_14440	COG0033	Phosphoglucomutase
C5P03_14445	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
C5P03_14450	COG0596	Alpha beta hydrolase
C5P03_14465	COG0716	FMN binding
C5P03_14475	COG0735	belongs to the Fur family
C5P03_14480	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
C5P03_14495	COG2190	(PTS) system
C5P03_14495	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C5P03_14495	COG1263	PTS System
C5P03_14500	COG0363	glucosamine-6-phosphate deaminase activity
C5P03_14505	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
C5P03_14510	COG1846	Transcriptional regulator
C5P03_14510	COG1940	carbohydrate kinase activity
C5P03_14540	COG0438	transferase activity, transferring glycosyl groups
C5P03_14555	COG3321	synthase
C5P03_14555	COG0604	alcohol dehydrogenase
C5P03_14580	COG1484	DNA-dependent DNA replication
C5P03_14585	COG4584	PFAM Integrase catalytic
C5P03_14595	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
C5P03_14615	COG0217	transcriptional regulatory protein
C5P03_14620	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
C5P03_14630	COG4106	trans-aconitate 2-methyltransferase activity
C5P03_14635	COG0500	methyltransferase
C5P03_14655	COG0450	alkyl hydroperoxide reductase
C5P03_14665	COG0583	DNA-binding transcription factor activity
C5P03_14675	COG0791	NLP P60 protein
C5P03_14690	COG1309	transcriptional regulator
C5P03_14730	COG0534	Mate efflux family protein
C5P03_14740	COG2841	Protein conserved in bacteria
C5P03_14755	COG0633	Ferredoxin
C5P03_14755	COG0633	Ferredoxin
C5P03_14755	COG3217	Mosc domain protein beta barrel domain protein
C5P03_14755	COG3217	Mosc domain protein beta barrel domain protein
C5P03_14765	COG0501	Belongs to the peptidase M48B family
C5P03_14770	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
C5P03_14775	COG1073	alpha beta
C5P03_14775	COG2226	methyltransferase
C5P03_14780	COG0156	8-amino-7-oxononanoate synthase activity
C5P03_14785	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
C5P03_14805	COG0017	Asparaginyl-tRNA synthetase
C5P03_14810	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
C5P03_14825	COG0583	DNA-binding transcription factor activity
C5P03_14830	COG1393	Belongs to the ArsC family
C5P03_14835	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
C5P03_14840	COG1876	peptidase activity
C5P03_14850	COG3263	regulation of cellular component size
C5P03_14870	COG1280	lysine exporter protein (LysE YggA)
C5P03_14875	COG0840	transmembrane signaling receptor activity
C5P03_14895	COG1957	nucleoside hydrolase
C5P03_14910	COG1454	alcohol dehydrogenase
C5P03_14950	COG2894	cell division
C5P03_14960	COG4964	Belongs to the GSP D family
C5P03_14990	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
C5P03_14995	COG0702	epimerase
C5P03_15005	COG2867	negative regulation of translational initiation
C5P03_15010	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
C5P03_15095	COG0583	DNA-binding transcription factor activity
C5P03_15100	COG2610	gluconate transmembrane transporter activity
C5P03_15105	COG3048	D-serine ammonia-lyase activity
C5P03_15115	COG0538	isocitrate dehydrogenase activity
C5P03_15120	COG2207	Transcriptional regulator
C5P03_15150	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
C5P03_15155	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C5P03_15155	COG1263	PTS System
C5P03_15160	COG1609	Transcriptional regulator
C5P03_15180	COG2814	Major facilitator Superfamily
C5P03_15185	COG0109	protoheme IX farnesyltransferase activity
C5P03_15195	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
C5P03_15200	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
C5P03_15255	COG0708	Exodeoxyribonuclease III
C5P03_15280	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
C5P03_15285	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
C5P03_15295	COG0095	Lipoate-protein ligase
C5P03_15325	COG0640	Transcriptional regulator
C5P03_15345	COG1285	pathogenesis
C5P03_15375	COG0484	heat shock protein binding
C5P03_15380	COG0443	Heat shock 70 kDa protein
C5P03_15385	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
C5P03_15390	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
C5P03_15395	COG0497	DNA recombination
C5P03_15400	COG1227	inorganic diphosphatase activity
C5P03_15410	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
C5P03_15415	COG0577	efflux transmembrane transporter activity
C5P03_15415	COG1136	(ABC) transporter
C5P03_15420	COG1538	Outer membrane efflux protein
C5P03_15425	COG2375	cellular response to nickel ion
C5P03_15430	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
C5P03_15440	COG3328	transposase activity
C5P03_15445	COG2916	Histone family protein nucleoid-structuring protein H-NS
C5P03_15470	COG1917	Cupin 2, conserved barrel domain protein
C5P03_15470	COG2169	Transcriptional regulator
C5P03_15480	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
C5P03_15485	COG1396	sequence-specific DNA binding
C5P03_15485	COG1917	Cupin 2, conserved barrel domain protein
C5P03_15500	COG0531	amino acid
C5P03_15505	COG0531	amino acid
C5P03_15510	COG1283	sodium-dependent phosphate transmembrane transporter activity
C5P03_15520	COG3384	dioxygenase
C5P03_15535	COG0813	purine-nucleoside phosphorylase activity
C5P03_15550	COG1943	Transposase
C5P03_15575	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
C5P03_15580	COG0083	homoserine kinase activity
C5P03_15595	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
C5P03_15600	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
C5P03_15615	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
C5P03_15625	COG0745	RESPONSE REGULATOR receiver
C5P03_15640	COG4988	ABC transporter
C5P03_15645	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
C5P03_15665	COG1720	tRNA m6t6A37 methyltransferase activity
C5P03_15685	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
C5P03_15690	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
C5P03_15700	COG2190	(PTS) system
C5P03_15705	COG3706	GGDEF domain
C5P03_15715	COG3038	cytochrome b561
C5P03_15725	COG0419	ATPase involved in DNA repair
C5P03_15730	COG0420	3'-5' exonuclease activity
C5P03_15740	COG2974	May be involved in recombination
C5P03_15745	COG0405	Gamma-glutamyltransferase
C5P03_15750	COG4651	solute:proton antiporter activity
C5P03_15750	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
C5P03_15755	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
C5P03_15755	COG4651	solute:proton antiporter activity
C5P03_15770	COG0469	pyruvate kinase activity
C5P03_15775	COG1196	nuclear chromosome segregation
C5P03_15775	COG3264	Mechanosensitive ion channel
C5P03_15810	COG2801	Transposase and inactivated derivatives
C5P03_15815	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
C5P03_15825	COG3852	Histidine kinase
C5P03_15840	COG4662	Binding-protein-dependent transport system inner membrane component
C5P03_15850	COG0746	molybdenum cofactor guanylyltransferase activity
C5P03_15855	COG0303	'Molybdopterin
C5P03_15860	COG1289	transmembrane transporter activity
C5P03_15865	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
C5P03_15900	COG0784	Response regulator, receiver
C5P03_15900	COG2205	protein histidine kinase activity
C5P03_15915	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
C5P03_15920	COG0444	Belongs to the ABC transporter superfamily
C5P03_15925	COG4608	Belongs to the ABC transporter superfamily
C5P03_15935	COG2971	BadF BadG BcrA BcrD
C5P03_15945	COG0840	transmembrane signaling receptor activity
C5P03_15955	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
C5P03_15960	COG3724	N-succinylarginine dihydrolase activity
C5P03_15965	COG0616	signal peptide processing
C5P03_15970	COG1028	Short-chain dehydrogenase reductase Sdr
C5P03_15975	COG0583	DNA-binding transcription factor activity
C5P03_15985	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
C5P03_15995	COG0583	DNA-binding transcription factor activity
C5P03_16005	COG1881	PFAM PEBP family protein
C5P03_16060	COG3706	GGDEF domain
C5P03_16065	COG0037	tRNA processing
C5P03_16070	COG3590	peptidase
C5P03_16080	COG0488	(ABC) transporter
C5P03_16090	COG0531	amino acid
C5P03_16095	COG0814	amino acid
C5P03_16110	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
C5P03_16115	COG1982	Orn Lys Arg decarboxylase major
C5P03_16120	COG0531	amino acid
C5P03_16125	COG3710	Transcriptional regulator
C5P03_16130	COG0825	malonyl-CoA metabolic process
C5P03_16140	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
C5P03_16145	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
C5P03_16150	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
C5P03_16155	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
C5P03_16160	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
C5P03_16175	COG0750	zinc metalloprotease
C5P03_16180	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
C5P03_16185	COG0575	Belongs to the CDS family
C5P03_16190	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
C5P03_16195	COG0233	cytoplasmic translational termination
C5P03_16200	COG0528	UMP kinase activity
C5P03_16205	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
C5P03_16210	COG0052	Belongs to the universal ribosomal protein uS2 family
C5P03_16215	COG0024	Methionine aminopeptidase
C5P03_16220	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
C5P03_16225	COG2171	N-acyltransferase activity
C5P03_16235	COG1263	PTS System
C5P03_16235	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C5P03_16255	COG4580	involved in the transport of maltose and maltodextrins
C5P03_16265	COG0564	pseudouridine synthase activity
C5P03_16270	COG3098	single-species biofilm formation
C5P03_16295	COG5595	Zn-ribbon-containing, possibly nucleic-acid-binding protein (DUF2310)
C5P03_16305	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
C5P03_16305	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
C5P03_16315	COG3706	GGDEF domain
C5P03_16320	COG1611	Belongs to the LOG family
C5P03_16325	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
C5P03_16330	COG0473	3-isopropylmalate dehydrogenase activity
C5P03_16340	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
C5P03_16345	COG2363	Small membrane protein
C5P03_16355	COG0583	DNA-binding transcription factor activity
C5P03_16360	COG0840	transmembrane signaling receptor activity
C5P03_16365	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
C5P03_16380	COG1477	protein flavinylation
C5P03_16385	COG2871	sodium ion transport
C5P03_16390	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
C5P03_16395	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
C5P03_16400	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
C5P03_16405	COG1805	sodium ion transport
C5P03_16410	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
C5P03_16415	COG0271	Belongs to the BolA IbaG family
C5P03_16420	COG2813	Specifically methylates the guanine in position
C5P03_16430	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
C5P03_16440	COG2211	Major facilitator Superfamily
C5P03_16445	COG3248	Nucleoside-binding outer membrane protein
C5P03_16450	COG1666	GTP binding
C5P03_16455	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
C5P03_16480	COG3459	Glycosyltransferase 36 associated
C5P03_16495	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
C5P03_16495	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
C5P03_16500	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
C5P03_16510	COG1151	hydroxylamine reductase activity
C5P03_16515	COG0783	Belongs to the Dps family
C5P03_16540	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
C5P03_16555	COG0300	oxidoreductase activity
C5P03_16565	COG0415	Belongs to the DNA photolyase family
C5P03_16570	COG0789	Transcriptional regulator
C5P03_16575	COG3272	Protein of unknown function (DUF1722)
C5P03_16605	COG1605	Chorismate mutase
C5P03_16605	COG0077	Prephenate dehydratase
C5P03_16630	COG2133	pyrroloquinoline quinone binding
C5P03_16650	COG0300	oxidoreductase activity
C5P03_16675	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
C5P03_16690	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
C5P03_16700	COG3813	Protein conserved in bacteria
C5P03_16715	COG1280	lysine exporter protein (LysE YggA)
C5P03_16725	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
C5P03_16745	COG0643	Histidine kinase
C5P03_16745	COG2198	Histidine kinase
C5P03_16755	COG0835	chemotaxis
C5P03_16760	COG0840	transmembrane signaling receptor activity
C5P03_16770	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
C5P03_16775	COG2201	protein-glutamate methylesterase activity
C5P03_16780	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
C5P03_16830	COG2199	diguanylate cyclase activity
C5P03_16830	COG2200	EAL domain
C5P03_16830	COG2203	Gaf domain
C5P03_16840	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
C5P03_16845	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
C5P03_16850	COG0305	Participates in initiation and elongation during chromosome replication
C5P03_16855	COG0305	Participates in initiation and elongation during chromosome replication
C5P03_16875	COG0737	Belongs to the 5'-nucleotidase family
C5P03_16895	COG2204	response regulator
C5P03_16900	COG0545	Peptidyl-prolyl cis-trans isomerase
C5P03_16910	COG2900	Belongs to the SlyX family
C5P03_16915	COG1047	Peptidyl-prolyl cis-trans
C5P03_16920	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
C5P03_16930	COG0835	chemotaxis
C5P03_16930	COG0784	Response regulator, receiver
C5P03_16935	COG0429	hydrolase of the alpha beta-hydrolase fold
C5P03_16940	COG5001	Diguanylate cyclase
C5P03_16940	COG4251	negative regulation of phosphorylation
C5P03_16940	COG3706	GGDEF domain
C5P03_16940	COG2203	Gaf domain
C5P03_16945	COG3089	Belongs to the UPF0270 family
C5P03_16955	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
C5P03_16960	COG0463	Glycosyl transferase, family 2
C5P03_16970	COG0726	polysaccharide deacetylase
C5P03_16975	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
C5P03_16980	COG2076	Multidrug Resistance protein
C5P03_16985	COG2076	Multidrug Resistance protein
C5P03_16990	COG3954	Phosphoribulokinase
C5P03_17005	COG1765	OsmC-like protein
C5P03_17010	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
C5P03_17020	COG3397	chitin binding
C5P03_17045	COG3655	Transcriptional regulator
C5P03_17055	COG2814	Major facilitator Superfamily
C5P03_17060	COG4771	TonB-dependent receptor
C5P03_17080	COG0748	coenzyme F420 binding
C5P03_17085	COG3721	Heme iron utilization protein
C5P03_17095	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C5P03_17120	COG0488	(ABC) transporter
C5P03_17135	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
C5P03_17140	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
C5P03_17145	COG3178	'Phosphotransferase
C5P03_17150	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
C5P03_17160	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
C5P03_17165	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
C5P03_17175	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
C5P03_17190	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
C5P03_17200	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
C5P03_17220	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
C5P03_17225	COG0211	Belongs to the bacterial ribosomal protein bL27 family
C5P03_17230	COG0261	This protein binds to 23S rRNA in the presence of protein L20
C5P03_17235	COG0142	geranyltranstransferase activity
C5P03_17240	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
C5P03_17245	COG0330	HflC and HflK could
C5P03_17250	COG0330	HflC and HflK could
C5P03_17255	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
C5P03_17260	COG1923	regulation of RNA biosynthetic process
C5P03_17265	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
C5P03_17270	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
C5P03_17280	COG0802	atpase or kinase
C5P03_17310	COG2011	ABC-type metal ion transport system permease component
C5P03_17315	COG1464	Belongs to the NlpA lipoprotein family
C5P03_17325	COG0840	transmembrane signaling receptor activity
C5P03_17350	COG5002	protein histidine kinase activity
C5P03_17350	COG2198	Histidine kinase
C5P03_17350	COG0784	Response regulator, receiver
C5P03_17385	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
C5P03_17390	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
C5P03_17400	COG2716	regulation of RNA biosynthetic process
C5P03_17405	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
C5P03_17410	COG3013	Belongs to the UPF0304 family
C5P03_17415	COG3092	negative regulation of chromosome organization
C5P03_17420	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
C5P03_17425	COG0857	belongs to the CobB CobQ family
C5P03_17425	COG0280	phosphate acetyltransferase
C5P03_17430	COG0440	acetolactate synthase activity
C5P03_17435	COG0028	Belongs to the TPP enzyme family
C5P03_17450	COG0671	phosphoesterase, PA-phosphatase related
C5P03_17460	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
C5P03_17465	COG0473	3-isopropylmalate dehydrogenase activity
C5P03_17470	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
C5P03_17475	COG0066	3-isopropylmalate dehydratase activity
C5P03_17490	COG4143	(ABC) transporter
C5P03_17495	COG1178	ABC-type Fe3 transport system permease component
C5P03_17500	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
C5P03_17505	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
C5P03_17515	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
C5P03_17545	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
C5P03_17550	COG0564	pseudouridine synthase activity
C5P03_17560	COG5001	Diguanylate cyclase
C5P03_17560	COG3300	MHYT domain
C5P03_17570	COG0459	protein refolding
C5P03_17575	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
C5P03_17585	COG3030	protein affecting phage T7 exclusion by the F plasmid
C5P03_17590	COG1027	Aspartate ammonia-lyase
C5P03_17595	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
C5P03_17605	COG0477	Major facilitator Superfamily
C5P03_17620	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
C5P03_17625	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
C5P03_17650	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
C5P03_17655	COG0635	Involved in the biosynthesis of porphyrin-containing compound
C5P03_17660	COG3036	rescue of stalled ribosome
C5P03_17665	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
C5P03_17675	COG0138	bifunctional purine biosynthesis protein purh
C5P03_17680	COG0151	Belongs to the GarS family
C5P03_17725	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
C5P03_17730	COG0358	DNA primase activity
C5P03_17735	COG1610	YqeY-like protein
C5P03_17740	COG0828	Belongs to the bacterial ribosomal protein bS21 family
C5P03_17745	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
C5P03_17755	COG1388	LysM domain
C5P03_17755	COG4942	peptidase
C5P03_17760	COG1238	metal cluster binding
C5P03_17765	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
C5P03_17770	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
C5P03_17775	COG0585	pseudouridine synthase activity
C5P03_17785	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
C5P03_17790	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
C5P03_17795	COG0148	phosphopyruvate hydratase activity
C5P03_17800	COG0504	CTP synthase activity
C5P03_17805	COG3956	TIGRFAM MazG family protein
C5P03_17810	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
C5P03_17815	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
C5P03_17825	COG4807	Protein conserved in bacteria
C5P03_17830	COG3023	N-Acetylmuramoyl-L-alanine amidase
C5P03_17835	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
C5P03_17840	COG1381	Involved in DNA repair and RecF pathway recombination
C5P03_17850	COG0571	ribonuclease III activity
C5P03_17855	COG0681	Belongs to the peptidase S26 family
C5P03_17860	COG0481	GTPase activity
C5P03_17875	COG3073	An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E
C5P03_17880	COG1595	DNA-templated transcription, initiation
C5P03_17885	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
C5P03_17935	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
C5P03_17940	COG0191	fructose-bisphosphate aldolase activity
C5P03_17945	COG0126	phosphoglycerate kinase activity
C5P03_17950	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
C5P03_17955	COG1940	carbohydrate kinase activity
C5P03_17975	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
C5P03_18010	COG0840	transmembrane signaling receptor activity
C5P03_18025	COG0529	Catalyzes the synthesis of activated sulfate
C5P03_18030	COG3273	potassium ion transport
C5P03_18030	COG0471	metal ion transport
C5P03_18035	COG2895	sulfate adenylyltransferase (ATP) activity
C5P03_18040	COG0175	sulfate reduction
C5P03_18045	COG1648	precorrin-2 dehydrogenase activity
C5P03_18045	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
C5P03_18050	COG0330	HflC and HflK could
C5P03_18055	COG1585	Membrane protein implicated in regulation of membrane protease activity
C5P03_18060	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
C5P03_18060	COG0517	IMP dehydrogenase activity
C5P03_18065	COG0488	(ABC) transporter
C5P03_18075	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
C5P03_18140	COG0789	Transcriptional regulator
C5P03_18150	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
C5P03_18155	COG1376	ErfK ybiS ycfS ynhG family protein
C5P03_18160	COG0668	transmembrane transport
C5P03_18170	COG2731	YhcH YjgK YiaL family protein
C5P03_18180	COG1794	racemase activity, acting on amino acids and derivatives
C5P03_18220	COG0733	neurotransmitter:sodium symporter activity
C5P03_18230	COG0733	neurotransmitter:sodium symporter activity
C5P03_18245	COG0561	phosphatase activity
C5P03_18275	COG1846	Transcriptional regulator
C5P03_18280	COG1764	response to oxidative stress
C5P03_18285	COG2130	NADP-dependent
C5P03_18290	COG0494	nUDIX hydrolase
C5P03_18305	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
C5P03_18310	COG1349	DNA-binding transcription factor activity
C5P03_18320	COG1028	Short-chain dehydrogenase reductase Sdr
C5P03_18335	COG3730	PTS system glucitol sorbitol-specific
C5P03_18340	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
C5P03_18365	COG2982	Protein involved in outer membrane biogenesis
C5P03_18370	COG1505	serine-type exopeptidase activity
C5P03_18375	COG0577	efflux transmembrane transporter activity
C5P03_18375	COG1136	(ABC) transporter
C5P03_18380	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
C5P03_18385	COG0745	RESPONSE REGULATOR receiver
C5P03_18390	COG2205	protein histidine kinase activity
C5P03_18395	COG2816	NAD+ diphosphatase activity
C5P03_18455	COG1912	Pfam S-adenosyl-l-methionine hydroxide adenosyltransferase
C5P03_18475	COG0513	Belongs to the DEAD box helicase family
C5P03_18500	COG2957	Belongs to the agmatine deiminase family
C5P03_18510	COG4221	oxidoreductase activity
C5P03_18525	COG1024	Enoyl-CoA hydratase
C5P03_18535	COG0110	maltose O-acetyltransferase activity
C5P03_18545	COG4166	transmembrane transport
C5P03_18560	COG1872	DUF167
C5P03_18565	COG0762	integral membrane protein
C5P03_18570	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
C5P03_18575	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
C5P03_18590	COG3022	response to hydroperoxide
C5P03_18595	COG0513	Belongs to the DEAD box helicase family
C5P03_18600	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
C5P03_18620	COG0735	belongs to the Fur family
C5P03_18625	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
C5P03_18640	COG0776	regulation of translation
C5P03_18645	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
C5P03_18670	COG0560	Phosphoserine phosphatase
C5P03_18680	COG0813	purine-nucleoside phosphorylase activity
C5P03_18685	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
C5P03_18690	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
C5P03_18695	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
C5P03_18705	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
C5P03_18710	COG0084	hydrolase, TatD family'
C5P03_18730	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
C5P03_18735	COG0004	ammonium transporteR
C5P03_18785	COG3561	AntA/AntB antirepressor
C5P03_18805	COG0582	viral genome integration into host DNA
C5P03_18810	COG4974	Belongs to the 'phage' integrase family
C5P03_18815	COG2932	Transcriptional regulator
C5P03_18890	COG4695	Portal protein
C5P03_19030	COG0795	lipopolysaccharide-transporting ATPase activity
C5P03_19035	COG0795	lipopolysaccharide-transporting ATPase activity
C5P03_19040	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
C5P03_19045	COG2927	DNA polymerase III (CHI subunit)
C5P03_19055	COG1253	flavin adenine dinucleotide binding
C5P03_19060	COG0586	Pfam SNARE associated Golgi protein
C5P03_19065	COG1686	Belongs to the peptidase S11 family
C5P03_19090	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
C5P03_19095	COG0527	aspartate kinase activity
C5P03_19100	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
C5P03_19110	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
C5P03_19115	COG1546	Belongs to the CinA family
C5P03_19120	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
C5P03_19155	COG1380	Effector of murein hydrolase LrgA
C5P03_19160	COG1346	cytolysis
C5P03_19175	COG0460	homoserine dehydrogenase
C5P03_19175	COG0527	aspartate kinase activity
C5P03_19180	COG0626	cystathionine gamma-synthase activity
C5P03_19195	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
C5P03_19200	COG0814	amino acid
C5P03_19205	COG1218	3'(2'),5'-bisphosphate nucleotidase
C5P03_19210	COG0494	nUDIX hydrolase
C5P03_19215	COG1011	Hydrolase
C5P03_19220	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
C5P03_19235	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
C5P03_19245	COG3156	type II secretion system protein K
C5P03_19250	COG4795	General secretion pathway protein
C5P03_19255	COG2165	general secretion pathway protein
C5P03_19265	COG2165	general secretion pathway protein
C5P03_19270	COG1459	type II secretion system
C5P03_19275	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
C5P03_19295	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
C5P03_19300	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
C5P03_19320	COG0456	acetyltransferase
C5P03_19325	COG3133	Outer membrane lipoprotein
C5P03_19340	COG2771	luxR family
C5P03_19355	COG4776	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction
C5P03_19370	COG2213	PTS system mannitol-specific
C5P03_19370	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
C5P03_19375	COG0246	Mannitol dehydrogenase
C5P03_19380	COG3722	fumarate hydratase activity
C5P03_19385	COG3263	regulation of cellular component size
C5P03_19390	COG0484	heat shock protein binding
C5P03_19410	COG1671	Belongs to the UPF0178 family
C5P03_19425	COG1988	membrane-bound metal-dependent
C5P03_19430	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
C5P03_19435	COG0513	Belongs to the DEAD box helicase family
C5P03_19460	COG1575	Belongs to the MenA family. Type 1 subfamily
C5P03_19465	COG1169	isochorismate synthase
C5P03_19470	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
C5P03_19475	COG0596	Alpha beta hydrolase
C5P03_19480	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
C5P03_19490	COG0318	PFAM AMP-dependent synthetase and ligase
C5P03_19505	COG3539	Fimbrial protein
C5P03_19510	COG3121	Chaperone
C5P03_19515	COG3188	usher protein
C5P03_19525	COG3539	Fimbrial protein
C5P03_19540	COG3291	Pkd domain containing protein
C5P03_19545	COG2949	membrane
C5P03_19560	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
C5P03_19565	COG5380	lipid catabolic process
C5P03_19580	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
C5P03_19585	COG4533	DNA binding
C5P03_19595	COG2873	o-acetylhomoserine
C5P03_19605	COG1979	alcohol dehydrogenase
C5P03_19625	COG4221	oxidoreductase activity
C5P03_19645	COG1285	pathogenesis
C5P03_19665	COG1368	sulfuric ester hydrolase activity
C5P03_19670	COG1522	sequence-specific DNA binding
C5P03_19680	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
C5P03_19685	COG1418	mRNA catabolic process
C5P03_19690	COG1058	Belongs to the CinA family
C5P03_19690	COG1546	Belongs to the CinA family
C5P03_19700	COG0842	Transport permease protein
C5P03_19700	COG1129	ABC transporter
C5P03_19715	COG0561	phosphatase activity
C5P03_19720	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
C5P03_19730	COG0668	transmembrane transport
C5P03_19740	COG1011	Hydrolase
C5P03_19755	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
C5P03_19760	COG0019	diaminopimelate decarboxylase activity
C5P03_19765	COG1965	Belongs to the frataxin family
C5P03_19785	COG3072	Adenylate cyclase
C5P03_19790	COG0181	hydroxymethylbilane synthase activity
C5P03_19800	COG2959	enzyme of heme biosynthesis
C5P03_19815	COG1494	fructose-1,6-bisphosphatase
C5P03_19865	COG3932	Exopolysaccharide synthesis, ExoD
C5P03_19870	COG0814	amino acid
C5P03_19885	COG3417	Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1B (PBP1b)
C5P03_19890	COG0110	maltose O-acetyltransferase activity
C5P03_19935	COG2022	thiamine diphosphate biosynthetic process
C5P03_19945	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
C5P03_19950	COG0352	thiamine-phosphate diphosphorylase activity
C5P03_19955	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
C5P03_19975	COG0745	RESPONSE REGULATOR receiver
C5P03_19985	COG0189	ligase activity
C5P03_20010	COG1639	'signal transduction protein
C5P03_20020	COG3700	Belongs to the class B bacterial acid phosphatase family
C5P03_20030	COG1366	Belongs to the anti-sigma-factor antagonist family
C5P03_20035	COG2172	sigma factor antagonist activity
C5P03_20040	COG2205	protein histidine kinase activity
C5P03_20040	COG0784	Response regulator, receiver
C5P03_20040	COG5002	protein histidine kinase activity
C5P03_20045	COG3437	response regulator, receiver
C5P03_20070	COG0312	modulator of DNA gyrase
C5P03_20075	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
C5P03_20085	COG3164	Protein of unknown function
C5P03_20090	COG1530	ribonuclease E activity
C5P03_20095	COG0424	maF-like protein
C5P03_20100	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
C5P03_20105	COG1792	Involved in formation and maintenance of cell shape
C5P03_20110	COG1077	Cell shape determining protein MreB Mrl
C5P03_20170	COG2199	diguanylate cyclase activity
C5P03_20170	COG2200	EAL domain
C5P03_20180	COG0387	Pfam Sodium calcium exchanger
C5P03_20185	COG2986	histidine ammonia-lyase
C5P03_20190	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
C5P03_20195	COG0010	Belongs to the arginase family
C5P03_20200	COG1228	amidohydrolase
C5P03_20205	COG2188	Transcriptional regulator
C5P03_20210	COG0288	reversible hydration of carbon dioxide
C5P03_20220	COG2177	Part of the ABC transporter FtsEX involved in
C5P03_20225	COG2884	Cell division ATP-binding protein ftsE
C5P03_20230	COG0552	protein localization to endoplasmic reticulum
C5P03_20235	COG0742	ribosomal rna small subunit methyltransferase
C5P03_20265	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
C5P03_20270	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
C5P03_20280	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
C5P03_20290	COG2095	MarC family integral membrane protein
C5P03_20300	COG1301	dicarboxylic acid transport
C5P03_20325	COG3714	YhhN family
C5P03_20350	COG1770	oligopeptidase
C5P03_20365	COG2249	NAD(P)H dehydrogenase (quinone) activity
C5P03_20400	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
C5P03_20420	COG2197	response regulator
C5P03_20425	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
C5P03_20435	COG1278	Cold shock
C5P03_20445	COG3706	GGDEF domain
C5P03_20450	COG2205	protein histidine kinase activity
C5P03_20455	COG0745	RESPONSE REGULATOR receiver
C5P03_20475	COG0840	transmembrane signaling receptor activity
C5P03_20485	COG3706	GGDEF domain
C5P03_20485	COG0745	RESPONSE REGULATOR receiver
C5P03_20490	COG0347	Belongs to the P(II) protein family
C5P03_20495	COG0004	ammonium transporteR
C5P03_20510	COG0346	lactoylglutathione lyase activity
C5P03_20520	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
C5P03_20525	COG1074	ATP-dependent DNA helicase activity
C5P03_20530	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
C5P03_20535	COG2259	Doxx family
C5P03_20540	COG1741	Belongs to the pirin family
C5P03_20575	COG1176	ABC-type spermidine putrescine transport system, permease component I
C5P03_20585	COG3842	ATPase activity
C5P03_20595	COG2203	Gaf domain
C5P03_20595	COG2199	diguanylate cyclase activity
C5P03_20620	COG0753	catalase activity
C5P03_20645	COG0494	nUDIX hydrolase
C5P03_20650	COG0628	permease
C5P03_20655	COG3284	Transcriptional regulator
C5P03_20665	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
C5P03_20665	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
C5P03_20665	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
C5P03_20670	COG1461	Dihydroxyacetone kinase
C5P03_20675	COG2376	Dihydroxyacetone kinase
C5P03_20685	COG4584	PFAM Integrase catalytic
C5P03_20690	COG1484	DNA-dependent DNA replication
C5P03_20740	COG0203	ribosomal protein L17
C5P03_20745	COG0202	RNA polymerase activity
C5P03_20750	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
C5P03_20755	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
C5P03_20760	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
C5P03_20765	COG0257	Belongs to the bacterial ribosomal protein bL36 family
C5P03_20770	COG0201	protein transport
C5P03_20775	COG0200	Binds to the 23S rRNA
C5P03_20780	COG1841	ribosomal large subunit assembly
C5P03_20785	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
C5P03_20790	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
C5P03_20795	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
C5P03_20800	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
C5P03_20805	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
C5P03_20810	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
C5P03_20815	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
C5P03_20820	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
C5P03_20825	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
C5P03_20830	COG0255	Belongs to the universal ribosomal protein uL29 family
C5P03_20835	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
C5P03_20840	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
C5P03_20845	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
C5P03_20850	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
C5P03_20855	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
C5P03_20860	COG0089	rRNA binding
C5P03_20865	COG0088	Forms part of the polypeptide exit tunnel
C5P03_20870	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
C5P03_20875	COG0051	transcription antitermination factor activity, RNA binding
C5P03_20890	COG0745	RESPONSE REGULATOR receiver
C5P03_20895	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
C5P03_20900	COG2183	response to ionizing radiation
C5P03_20920	COG0596	Alpha beta hydrolase
C5P03_20925	COG1040	competence protein
C5P03_20930	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
C5P03_20930	COG0316	Belongs to the HesB IscA family
C5P03_20935	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
C5P03_20940	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
C5P03_20945	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
C5P03_20950	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
C5P03_20955	COG4942	peptidase
C5P03_20965	COG1609	Transcriptional regulator
C5P03_20970	COG0800	Aldolase
C5P03_20975	COG0129	dihydroxy-acid dehydratase activity
C5P03_20980	COG3265	gluconokinase activity
C5P03_20985	COG2610	gluconate transmembrane transporter activity
C5P03_20990	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
C5P03_20995	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
C5P03_21005	COG0456	acetyltransferase
C5P03_21020	COG1295	ribonuclease BN
C5P03_21030	COG0174	glutamine synthetase
C5P03_21040	COG3852	Histidine kinase
C5P03_21045	COG2204	response regulator
C5P03_21050	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
C5P03_21055	COG0635	Involved in the biosynthesis of porphyrin-containing compound
C5P03_21065	COG3078	GTPase activator activity
C5P03_21075	COG0218	Necessary for normal cell division and for the maintenance of normal septation
C5P03_21085	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
C5P03_21090	COG0408	coproporphyrinogen oxidase activity
C5P03_21095	COG0009	L-threonylcarbamoyladenylate synthase
C5P03_21105	COG0551	DNA topoisomerase type I activity
C5P03_21110	COG2922	Belongs to the Smg family
C5P03_21115	COG0758	DNA mediated transformation
C5P03_21120	COG1652	LysM domain
C5P03_21125	COG0242	peptide deformylase activity
C5P03_21130	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
C5P03_21135	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
C5P03_21135	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
C5P03_21140	COG0569	domain protein
C5P03_21145	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
C5P03_21150	COG1322	Protein conserved in bacteria
C5P03_21170	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
C5P03_21175	COG0686	Belongs to the AlaDH PNT family
C5P03_21180	COG0519	Catalyzes the synthesis of GMP from XMP
C5P03_21180	COG0518	GMP synthase (glutamine-hydrolyzing) activity
C5P03_21200	COG1012	belongs to the aldehyde dehydrogenase family
C5P03_21210	COG2962	Rard protein
C5P03_21220	COG1280	lysine exporter protein (LysE YggA)
C5P03_21230	COG2391	methyltransferase activity
C5P03_21235	COG1280	lysine exporter protein (LysE YggA)
C5P03_21240	COG0583	DNA-binding transcription factor activity
C5P03_21260	COG2823	Periplasmic or secreted lipoprotein
C5P03_21300	COG0210	DNA helicase
C5P03_21325	COG0583	DNA-binding transcription factor activity
C5P03_21345	COG1262	PFAM Formylglycine-generating sulfatase enzyme
C5P03_21350	COG0385	Bile acid
C5P03_21400	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
C5P03_21415	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
C5P03_21420	COG3074	FtsZ-dependent cytokinesis
C5P03_21430	COG1045	serine acetyltransferase
C5P03_21440	COG0745	RESPONSE REGULATOR receiver
C5P03_21445	COG2205	protein histidine kinase activity
C5P03_21450	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
C5P03_21470	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
C5P03_21475	COG2937	Belongs to the GPAT DAPAT family
C5P03_21480	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
C5P03_21485	COG3161	chorismate lyase activity
C5P03_21490	COG1580	Controls the rotational direction of flagella during chemotaxis
C5P03_21515	COG1609	Transcriptional regulator
C5P03_21520	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
C5P03_21535	COG1519	Transferase
C5P03_21540	COG0859	PFAM glycosyl transferase family 9
C5P03_21545	COG0463	Glycosyl transferase, family 2
C5P03_21550	COG0859	PFAM glycosyl transferase family 9
C5P03_21555	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
C5P03_21560	COG2990	Protein conserved in bacteria
C5P03_21565	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
C5P03_21575	COG0267	Belongs to the bacterial ribosomal protein bL33 family
C5P03_21580	COG0227	Belongs to the bacterial ribosomal protein bL28 family
C5P03_21585	COG2003	Belongs to the UPF0758 family
C5P03_21590	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
C5P03_21595	COG0756	dUTP diphosphatase activity
C5P03_21600	COG1309	transcriptional regulator
C5P03_21605	COG0668	transmembrane transport
C5P03_21620	COG0166	Belongs to the GPI family
C5P03_21625	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
C5P03_21630	COG0583	DNA-binding transcription factor activity
C5P03_21670	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
C5P03_21675	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
C5P03_21680	COG1739	Uncharacterized protein family UPF0029
C5P03_21685	COG0006	proline dipeptidase activity
C5P03_21690	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
C5P03_21695	COG1250	3-hydroxyacyl-CoA dehydrogenase
C5P03_21695	COG1024	Enoyl-CoA hydratase
C5P03_21700	COG0183	Belongs to the thiolase family
C5P03_21705	COG0745	RESPONSE REGULATOR receiver
C5P03_21710	COG2205	protein histidine kinase activity
C5P03_21725	COG0425	Belongs to the sulfur carrier protein TusA family
C5P03_21730	COG0251	oxidation-reduction process
C5P03_21735	COG2885	chlorophyll binding
C5P03_21740	COG2818	Glycosylase
C5P03_21745	COG0752	glycyl-tRNA synthetase alpha subunit
C5P03_21750	COG0751	glycine-tRNA ligase activity
C5P03_21760	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
C5P03_21770	COG2200	EAL domain
C5P03_21770	COG2202	Pas domain
C5P03_21770	COG2199	diguanylate cyclase activity
C5P03_21785	COG0814	amino acid
C5P03_21790	COG0348	domain, Protein
C5P03_21800	COG0446	pyridine nucleotide-disulphide oxidoreductase
C5P03_21805	COG0426	domain, Protein
C5P03_21805	COG1773	rubredoxin
C5P03_21810	COG3604	Transcriptional regulator
C5P03_21815	COG2188	Transcriptional regulator
C5P03_21830	COG1609	Transcriptional regulator
C5P03_21840	COG0559	Belongs to the binding-protein-dependent transport system permease family
C5P03_21870	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
C5P03_21895	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
C5P03_21905	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
C5P03_21910	COG3118	belongs to the thioredoxin family
C5P03_21915	COG0513	Belongs to the DEAD box helicase family
C5P03_21920	COG0248	Ppx GppA phosphatase
C5P03_21930	COG0742	ribosomal rna small subunit methyltransferase
C5P03_21935	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C5P03_21955	COG0084	hydrolase, TatD family'
C5P03_21960	COG0805	protein transport
C5P03_21965	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
C5P03_21975	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
C5P03_21980	COG3165	ubiquinone biosynthetic process from chorismate
C5P03_21990	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
C5P03_22035	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
C5P03_22040	COG0848	biopolymer transport protein
C5P03_22045	COG0811	peptide transport
C5P03_22050	COG0811	peptide transport
C5P03_22060	COG2771	luxR family
C5P03_22090	COG1484	DNA-dependent DNA replication
C5P03_22095	COG4584	PFAM Integrase catalytic
C5P03_22150	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
C5P03_22155	COG1349	DNA-binding transcription factor activity
C5P03_22160	COG0745	RESPONSE REGULATOR receiver
C5P03_22165	COG2205	protein histidine kinase activity
C5P03_22175	COG4452	Inner membrane protein CreD
C5P03_22180	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
C5P03_22185	COG0355	proton-transporting ATP synthase activity, rotational mechanism
C5P03_22190	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
C5P03_22195	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
C5P03_22200	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
C5P03_22205	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
C5P03_22210	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
C5P03_22220	COG0356	it plays a direct role in the translocation of protons across the membrane
C5P03_22225	COG3312	ion transport
C5P03_22230	COG1475	DNA binding
C5P03_22235	COG1192	Involved in chromosome partitioning
C5P03_22240	COG0357	Ribosomal RNA small subunit methyltransferase G
C5P03_22245	COG0445	tRNA wobble uridine modification
C5P03_22250	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
C5P03_22255	COG4774	siderophore transport
C5P03_22260	COG4615	Cyclic peptide transporter
C5P03_22265	COG1120	ATPase activity
C5P03_22270	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
C5P03_22280	COG4774	siderophore transport
C5P03_22285	COG4607	ABC-type enterochelin transport system periplasmic component
C5P03_22290	COG4604	ABC transporter, ATP-binding protein
C5P03_22295	COG4605	iron ion homeostasis
C5P03_22300	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C5P03_22320	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
C5P03_22330	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
C5P03_22345	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
C5P03_22350	COG0706	membrane insertase activity
C5P03_22355	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
C5P03_22360	COG0594	ribonuclease P activity
C5P03_22365	COG0230	Belongs to the bacterial ribosomal protein bL34 family