locus-tag	class	description
AXA69_000055	COG4737	Cytotoxic translational repressor of toxin-antitoxin stability system
AXA69_000080	COG0322	excinuclease ABC activity
AXA69_000085	COG2197	response regulator
AXA69_000090	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
AXA69_000095	COG2835	tetraacyldisaccharide 4'-kinase activity
AXA69_000100	COG1663	tetraacyldisaccharide 4'-kinase activity
AXA69_000105	COG1132	(ABC) transporter
AXA69_000110	COG2333	competence protein COMEC
AXA69_000110	COG0658	competence protein
AXA69_000125	COG0433	COG0433 Predicted ATPase
AXA69_000130	COG1448	Aminotransferase
AXA69_000145	COG1199	ATP-dependent helicase activity
AXA69_000155	COG0123	including yeast histone deacetylase and acetoin utilization protein
AXA69_000160	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
AXA69_000165	COG1785	Belongs to the alkaline phosphatase family
AXA69_000185	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
AXA69_000200	COG2271	Major facilitator Superfamily
AXA69_000205	COG3706	GGDEF domain
AXA69_000210	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AXA69_000215	COG0765	amino acid transport
AXA69_000220	COG1126	abc transporter atp-binding protein
AXA69_000230	COG0531	amino acid
AXA69_000245	COG1253	flavin adenine dinucleotide binding
AXA69_000250	COG0704	Plays a role in the regulation of phosphate uptake
AXA69_000260	COG0581	inorganic phosphate transmembrane transporter activity
AXA69_000265	COG0573	inorganic phosphate transmembrane transporter activity
AXA69_000270	COG0590	tRNA wobble adenosine to inosine editing
AXA69_000280	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
AXA69_000300	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
AXA69_000305	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
AXA69_000310	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
AXA69_000315	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
AXA69_000325	COG3852	Histidine kinase
AXA69_000345	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
AXA69_000350	COG0248	Ppx GppA phosphatase
AXA69_000355	COG2239	Acts as a magnesium transporter
AXA69_000375	COG1706	bacterial-type flagellum-dependent cell motility
AXA69_000380	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
AXA69_000390	COG4787	bacterial-type flagellum-dependent cell motility
AXA69_000410	COG1815	bacterial-type flagellum-dependent cell motility
AXA69_000420	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
AXA69_000425	COG0835	chemotaxis
AXA69_000425	COG0784	Response regulator, receiver
AXA69_000445	COG0622	Phosphoesterase
AXA69_000450	COG4166	transmembrane transport
AXA69_000505	COG1278	Cold shock
AXA69_000545	COG1484	DNA-dependent DNA replication
AXA69_000550	COG4584	PFAM Integrase catalytic
AXA69_000565	COG3132	Protein of unknown function, DUF480
AXA69_000575	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
AXA69_000590	COG0438	transferase activity, transferring glycosyl groups
AXA69_000625	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
AXA69_000645	COG0471	metal ion transport
AXA69_000645	COG0490	domain, Protein
AXA69_000650	COG3273	potassium ion transport
AXA69_000650	COG0471	metal ion transport
AXA69_000670	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
AXA69_000675	COG0438	transferase activity, transferring glycosyl groups
AXA69_000695	COG1450	Type ii and iii secretion system protein
AXA69_000735	COG1459	type II secretion system
AXA69_000740	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
AXA69_000760	COG1091	dTDP-4-dehydrorhamnose reductase activity
AXA69_000780	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AXA69_000785	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AXA69_000790	COG1309	transcriptional regulator
AXA69_000805	COG1946	Acyl-CoA thioesterase
AXA69_000815	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
AXA69_000825	COG0009	L-threonylcarbamoyladenylate synthase
AXA69_000835	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
AXA69_000840	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
AXA69_000840	COG0512	Glutamine amidotransferase of anthranilate synthase
AXA69_000845	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
AXA69_000850	COG0135	phosphoribosylanthranilate isomerase activity
AXA69_000850	COG0134	indole-3-glycerol-phosphate synthase activity
AXA69_000855	COG0133	tryptophan synthase activity
AXA69_000860	COG0159	tryptophan synthase activity
AXA69_000890	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
AXA69_000890	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AXA69_000890	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AXA69_000900	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AXA69_000920	COG0482	sulfurtransferase activity
AXA69_000925	COG2915	High frequency lysogenization protein hflD homolog
AXA69_000930	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
AXA69_000935	COG2850	peptidyl-arginine hydroxylation
AXA69_000955	COG3153	acetyltransferase
AXA69_000965	COG0625	glutathione transferase activity
AXA69_000970	COG0259	pyridoxamine-phosphate oxidase activity
AXA69_000985	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
AXA69_000985	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
AXA69_000990	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
AXA69_001010	COG3088	subunit of a heme lyase
AXA69_001010	COG4235	cytochrome complex assembly
AXA69_001015	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AXA69_001020	COG1138	Cytochrome C-type biogenesis protein
AXA69_001025	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
AXA69_001030	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
AXA69_001035	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
AXA69_001040	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
AXA69_001060	COG0835	chemotaxis
AXA69_001070	COG1192	Involved in chromosome partitioning
AXA69_001075	COG1360	Flagellar Motor Protein
AXA69_001080	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
AXA69_001085	COG2201	protein-glutamate methylesterase activity
AXA69_001090	COG0643	Histidine kinase
AXA69_001090	COG2198	Histidine kinase
AXA69_001090	COG0784	Response regulator, receiver
AXA69_001095	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
AXA69_001120	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
AXA69_001130	COG1684	flagellar biosynthetic protein fliR
AXA69_001185	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
AXA69_001195	COG1677	Flagellar hook-basal body complex protein FliE
AXA69_001205	COG1574	metal-dependent hydrolase with the TIM-barrel fold
AXA69_001220	COG1342	Belongs to the UPF0251 family
AXA69_001240	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
AXA69_001250	COG0745	RESPONSE REGULATOR receiver
AXA69_001255	COG3290	protein histidine kinase activity
AXA69_001265	COG1737	Transcriptional regulator
AXA69_001270	COG0469	pyruvate kinase activity
AXA69_001280	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AXA69_001285	COG1960	acyl-CoA dehydrogenase activity
AXA69_001295	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
AXA69_001330	COG3209	COG3209 Rhs family protein
AXA69_001340	COG1484	DNA-dependent DNA replication
AXA69_001345	COG4584	PFAM Integrase catalytic
AXA69_001380	COG1376	ErfK ybiS ycfS ynhG family protein
AXA69_001380	COG1388	LysM domain
AXA69_001395	COG3129	Specifically methylates the adenine in position 1618 of 23S rRNA
AXA69_001400	COG0791	NLP P60 protein
AXA69_001405	COG2091	lysine biosynthetic process via aminoadipic acid
AXA69_001410	COG3118	belongs to the thioredoxin family
AXA69_001420	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
AXA69_001425	COG0788	formyltetrahydrofolate deformylase activity
AXA69_001435	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AXA69_001455	COG0366	Alpha amylase catalytic
AXA69_001460	COG1196	nuclear chromosome segregation
AXA69_001460	COG0739	heme binding
AXA69_001460	COG0741	lytic transglycosylase activity
AXA69_001465	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
AXA69_001470	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
AXA69_001475	COG0673	inositol 2-dehydrogenase activity
AXA69_001510	COG1032	radical SAM domain protein
AXA69_001520	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AXA69_001525	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AXA69_001530	COG3706	GGDEF domain
AXA69_001535	COG1752	Esterase of the alpha-beta hydrolase superfamily
AXA69_001540	COG0733	neurotransmitter:sodium symporter activity
AXA69_001570	COG0281	malic enzyme
AXA69_001575	COG2207	Transcriptional regulator
AXA69_001580	COG0534	Mate efflux family protein
AXA69_001595	COG2233	PERMEase
AXA69_001600	COG0095	Lipoate-protein ligase
AXA69_001605	COG1115	amino acid carrier protein
AXA69_001610	COG0019	diaminopimelate decarboxylase activity
AXA69_001650	COG1131	(ABC) transporter
AXA69_001655	COG0545	Peptidyl-prolyl cis-trans isomerase
AXA69_001660	COG3142	Participates in the control of copper homeostasis
AXA69_001665	COG1940	carbohydrate kinase activity
AXA69_001685	COG5002	protein histidine kinase activity
AXA69_001690	COG0745	RESPONSE REGULATOR receiver
AXA69_001695	COG0346	lactoylglutathione lyase activity
AXA69_001725	COG3290	protein histidine kinase activity
AXA69_001730	COG0281	malic enzyme
AXA69_001745	COG1846	Transcriptional regulator
AXA69_001750	COG1566	PFAM secretion protein HlyD family protein
AXA69_001775	COG0602	queuosine metabolic process
AXA69_001785	COG1328	CTP reductase activity
AXA69_001795	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
AXA69_001800	COG3115	cell septum assembly
AXA69_001805	COG1196	nuclear chromosome segregation
AXA69_001815	COG2860	membrane
AXA69_001825	COG3108	Peptidase M15
AXA69_001830	COG2989	Protein conserved in bacteria
AXA69_001845	COG0463	Glycosyl transferase, family 2
AXA69_001860	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
AXA69_001865	COG0739	heme binding
AXA69_001870	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
AXA69_001885	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
AXA69_001895	COG3091	SprT-like family
AXA69_001905	COG1385	rRNA (uridine-N3-)-methyltransferase activity
AXA69_001910	COG0189	ligase activity
AXA69_001920	COG1678	Uncharacterized ACR, COG1678
AXA69_001925	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
AXA69_001945	COG0714	Associated with various cellular activities
AXA69_001960	COG1115	amino acid carrier protein
AXA69_001965	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
AXA69_001980	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
AXA69_002000	COG1301	dicarboxylic acid transport
AXA69_002025	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
AXA69_002030	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
AXA69_002035	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
AXA69_002040	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
AXA69_002050	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
AXA69_002055	COG0737	Belongs to the 5'-nucleotidase family
AXA69_002060	COG0193	aminoacyl-tRNA hydrolase activity
AXA69_002065	COG0012	GTP binding
AXA69_002130	COG0471	metal ion transport
AXA69_002130	COG0490	domain, Protein
AXA69_002140	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
AXA69_002170	COG0443	Heat shock 70 kDa protein
AXA69_002180	COG0366	Alpha amylase catalytic
AXA69_002195	COG0488	(ABC) transporter
AXA69_002205	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
AXA69_002205	COG1013	pyruvate-flavodoxin oxidoreductase activity
AXA69_002205	COG0674	pyruvate-flavodoxin oxidoreductase activity
AXA69_002205	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AXA69_002215	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AXA69_002225	COG1012	belongs to the aldehyde dehydrogenase family
AXA69_002235	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
AXA69_002250	COG0180	Tryptophanyl-tRNA synthetase
AXA69_002255	COG0546	phosphoglycolate phosphatase activity
AXA69_002260	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
AXA69_002265	COG0338	D12 class N6 adenine-specific DNA methyltransferase
AXA69_002275	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
AXA69_002280	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
AXA69_002310	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
AXA69_002315	COG0583	DNA-binding transcription factor activity
AXA69_002335	COG0583	DNA-binding transcription factor activity
AXA69_002350	COG0739	heme binding
AXA69_002365	COG3264	Mechanosensitive ion channel
AXA69_002365	COG1511	domain protein
AXA69_002370	COG0584	glycerophosphoryl diester phosphodiesterase
AXA69_002380	COG1053	succinate dehydrogenase
AXA69_002385	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
AXA69_002390	COG3029	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
AXA69_002395	COG3080	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
AXA69_002415	COG3214	Protein conserved in bacteria
AXA69_002450	COG0745	RESPONSE REGULATOR receiver
AXA69_002455	COG0642	Histidine kinase
AXA69_002465	COG0516	GMP reductase activity
AXA69_002475	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
AXA69_002485	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AXA69_002505	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AXA69_002520	COG3706	GGDEF domain
AXA69_002530	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AXA69_002535	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
AXA69_002540	COG1702	phosphate starvation-inducible protein PhoH
AXA69_002545	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
AXA69_002550	COG4535	Mg2 and Co2 transporter CorC
AXA69_002555	COG0815	Transfers the fatty acyl group on membrane lipoproteins
AXA69_002560	COG2888	peptidyl-tyrosine sulfation
AXA69_002565	COG0495	leucyl-tRNA aminoacylation
AXA69_002585	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
AXA69_002590	COG0799	negative regulation of ribosome biogenesis
AXA69_002595	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
AXA69_002600	COG0768	penicillin binding
AXA69_002605	COG0772	Belongs to the SEDS family
AXA69_002615	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
AXA69_002620	COG1686	Belongs to the peptidase S11 family
AXA69_002625	COG2921	Belongs to the UPF0250 family
AXA69_002630	COG0321	lipoyl(octanoyl) transferase activity
AXA69_002635	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
AXA69_002645	COG3621	Patatin-like phospholipase
AXA69_002670	COG1484	DNA-dependent DNA replication
AXA69_002675	COG4584	PFAM Integrase catalytic
AXA69_002720	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AXA69_002725	COG3545	Serine hydrolase
AXA69_002740	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
AXA69_002750	COG1970	mechanosensitive ion channel activity
AXA69_002755	COG3706	GGDEF domain
AXA69_002760	COG4974	Belongs to the 'phage' integrase family
AXA69_002775	COG0312	modulator of DNA gyrase
AXA69_002830	COG1422	Protein of unknown function (DUF1090)
AXA69_002835	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
AXA69_002840	COG3706	GGDEF domain
AXA69_002850	COG1185	polyribonucleotide nucleotidyltransferase activity
AXA69_002855	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
AXA69_002860	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
AXA69_002865	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
AXA69_002870	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
AXA69_002875	COG0195	Participates in both transcription termination and antitermination
AXA69_002880	COG0779	Required for maturation of 30S ribosomal subunits
AXA69_002895	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
AXA69_002900	COG0149	triose-phosphate isomerase activity
AXA69_002905	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AXA69_002910	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
AXA69_002920	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
AXA69_002925	COG1534	Rna-binding protein
AXA69_002950	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
AXA69_002955	COG1722	exodeoxyribonuclease VII activity
AXA69_002960	COG0142	geranyltranstransferase activity
AXA69_002965	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
AXA69_002985	COG4172	Belongs to the ABC transporter superfamily
AXA69_002990	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
AXA69_002995	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
AXA69_003000	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
AXA69_003005	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
AXA69_003020	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AXA69_003020	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AXA69_003025	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
AXA69_003040	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
AXA69_003050	COG3381	protein complex oligomerization
AXA69_003080	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AXA69_003085	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
AXA69_003090	COG0511	ligase activity, forming carbon-carbon bonds
AXA69_003095	COG0439	Biotin carboxylase
AXA69_003100	COG3924	membrane
AXA69_003105	COG4145	pantothenate transmembrane transporter activity
AXA69_003110	COG2190	(PTS) system
AXA69_003110	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AXA69_003110	COG1263	PTS System
AXA69_003115	COG0583	DNA-binding transcription factor activity
AXA69_003120	COG0604	alcohol dehydrogenase
AXA69_003125	COG2264	protein methyltransferase activity
AXA69_003135	COG4303	Ethanolamine ammonia lyase large subunit
AXA69_003140	COG4302	ethanolamine ammonia-lyase activity
AXA69_003160	COG0778	Nitroreductase
AXA69_003165	COG1902	pentaerythritol trinitrate reductase activity
AXA69_003165	COG0446	pyridine nucleotide-disulphide oxidoreductase
AXA69_003170	COG0616	signal peptide processing
AXA69_003190	COG3139	Protein of unknown function (DUF1315)
AXA69_003195	COG0252	asparaginase activity
AXA69_003200	COG0786	glutamate:sodium symporter activity
AXA69_003215	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
AXA69_003220	COG0384	phenazine biosynthesis protein PhzF
AXA69_003235	COG0175	sulfate reduction
AXA69_003240	COG2113	Glycine betaine
AXA69_003245	COG4176	ABC-type proline glycine betaine transport system permease component
AXA69_003250	COG4175	Glycine betaine
AXA69_003260	COG3610	response to peptide
AXA69_003265	COG2966	Psort location CytoplasmicMembrane, score
AXA69_003275	COG0521	Mo-molybdopterin cofactor biosynthetic process
AXA69_003285	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AXA69_003290	COG1028	Short-chain dehydrogenase reductase Sdr
AXA69_003300	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AXA69_003325	COG2986	histidine ammonia-lyase
AXA69_003340	COG0318	PFAM AMP-dependent synthetase and ligase
AXA69_003350	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AXA69_003355	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AXA69_003390	COG1858	cytochrome C peroxidase
AXA69_003400	COG2313	pseudouridylate synthase activity
AXA69_003405	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AXA69_003405	COG1522	sequence-specific DNA binding
AXA69_003435	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
AXA69_003440	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
AXA69_003455	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
AXA69_003465	COG2195	Cleaves the N-terminal amino acid of tripeptides
AXA69_003470	COG4608	Belongs to the ABC transporter superfamily
AXA69_003475	COG0444	Belongs to the ABC transporter superfamily
AXA69_003480	COG0747	negative chemotaxis
AXA69_003485	COG4239	(ABC) transporter, permease
AXA69_003495	COG4206	TonB-dependent receptor
AXA69_003505	COG0811	peptide transport
AXA69_003510	COG0811	peptide transport
AXA69_003515	COG0848	biopolymer transport protein
AXA69_003560	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AXA69_003565	COG0840	transmembrane signaling receptor activity
AXA69_003575	COG1278	Cold shock
AXA69_003605	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
AXA69_003615	COG0688	phosphatidylethanolamine metabolic process
AXA69_003620	COG4628	conserved protein (DUF2132)
AXA69_003640	COG3300	MHYT domain
AXA69_003640	COG5001	Diguanylate cyclase
AXA69_003645	COG3076	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome
AXA69_003675	COG1012	belongs to the aldehyde dehydrogenase family
AXA69_003685	COG1132	(ABC) transporter
AXA69_003695	COG2897	thiosulfate sulfurtransferase activity
AXA69_003700	COG2066	Belongs to the glutaminase family
AXA69_003705	COG3171	Protein conserved in bacteria
AXA69_003710	COG0220	tRNA (guanine-N7-)-methyltransferase activity
AXA69_003725	COG2200	EAL domain
AXA69_003730	COG1090	epimerase
AXA69_003735	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
AXA69_003740	COG4181	ATPase activity
AXA69_003745	COG2755	lipolytic protein G-D-S-L family
AXA69_003750	COG0784	Response regulator, receiver
AXA69_003750	COG0835	chemotaxis
AXA69_003760	COG0569	domain protein
AXA69_003760	COG2985	domain, Protein
AXA69_003765	COG1272	protein, Hemolysin III
AXA69_003770	COG0076	glutamate decarboxylase activity
AXA69_003775	COG2917	probably involved in intracellular septation
AXA69_003780	COG2350	Protein conserved in bacteria
AXA69_003790	COG1555	photosystem II stabilization
AXA69_003795	COG1210	Utp--glucose-1-phosphate uridylyltransferase
AXA69_003800	COG3104	oligopeptide transport
AXA69_003805	COG0745	RESPONSE REGULATOR receiver
AXA69_003835	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AXA69_003850	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
AXA69_003855	COG1280	lysine exporter protein (LysE YggA)
AXA69_003885	COG0316	Belongs to the HesB IscA family
AXA69_003895	COG0038	chloride channel
AXA69_003900	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
AXA69_003915	COG0671	phosphoesterase, PA-phosphatase related
AXA69_003925	COG0784	Response regulator, receiver
AXA69_003925	COG3437	response regulator, receiver
AXA69_003930	COG0583	DNA-binding transcription factor activity
AXA69_003935	COG2076	Multidrug Resistance protein
AXA69_003945	COG0346	lactoylglutathione lyase activity
AXA69_003950	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AXA69_003955	COG1643	Atp-dependent helicase
AXA69_003965	COG1489	DNA binding
AXA69_003970	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
AXA69_003975	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AXA69_003980	COG0617	tRNA 3'-terminal CCA addition
AXA69_003985	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
AXA69_003990	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
AXA69_003995	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
AXA69_004005	COG0842	Transport permease protein
AXA69_004010	COG1131	(ABC) transporter
AXA69_004025	COG0163	prenyltransferase activity
AXA69_004030	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
AXA69_004035	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
AXA69_004040	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
AXA69_004050	COG0506	proline dehydrogenase activity
AXA69_004050	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
AXA69_004050	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
AXA69_004055	COG4991	sh3 domain protein
AXA69_004060	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AXA69_004080	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
AXA69_004085	COG1640	4-alpha-glucanotransferase
AXA69_004090	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
AXA69_004095	COG0676	glucose-6-phosphate 1-epimerase activity
AXA69_004100	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
AXA69_004170	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
AXA69_004175	COG2885	chlorophyll binding
AXA69_004180	COG0823	Involved in the tonB-independent uptake of proteins
AXA69_004195	COG0811	peptide transport
AXA69_004200	COG0824	Thioesterase
AXA69_004205	COG3790	cyd operon protein YbgE
AXA69_004210	COG4890	Cyd operon protein YbgT
AXA69_004215	COG1294	oxidase, subunit
AXA69_004220	COG1271	oxidase subunit
AXA69_004225	COG2255	four-way junction helicase activity
AXA69_004230	COG0632	four-way junction helicase activity
AXA69_004235	COG0840	transmembrane signaling receptor activity
AXA69_004240	COG0442	prolyl-tRNA aminoacylation
AXA69_004250	COG1902	pentaerythritol trinitrate reductase activity
AXA69_004260	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
AXA69_004290	COG0714	Associated with various cellular activities
AXA69_004300	COG0456	acetyltransferase
AXA69_004310	COG1022	Amp-dependent synthetase and ligase
AXA69_004320	COG2918	glutathione biosynthetic process
AXA69_004325	COG0612	Peptidase, M16
AXA69_004330	COG1238	metal cluster binding
AXA69_004335	COG1064	alcohol dehydrogenase
AXA69_004360	COG0359	binds to the 23S rRNA
AXA69_004365	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
AXA69_004370	COG0360	Binds together with S18 to 16S ribosomal RNA
AXA69_004375	COG1914	H( )-stimulated, divalent metal cation uptake system
AXA69_004395	COG2153	protein acetylation
AXA69_004405	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AXA69_004410	COG0557	exoribonuclease II activity
AXA69_004415	COG3706	GGDEF domain
AXA69_004420	COG1854	S-ribosylhomocysteine lyase activity
AXA69_004435	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AXA69_004435	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
AXA69_004470	COG4968	Prepilin-type N-terminal cleavage methylation domain
AXA69_004475	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
AXA69_004480	COG1047	Peptidyl-prolyl cis-trans
AXA69_004485	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
AXA69_004490	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
AXA69_004495	COG0196	riboflavin kinase activity
AXA69_004500	COG0728	peptidoglycan biosynthetic process
AXA69_004505	COG0268	Binds directly to 16S ribosomal RNA
AXA69_004510	COG0640	Transcriptional regulator
AXA69_004515	COG0583	DNA-binding transcription factor activity
AXA69_004525	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
AXA69_004530	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
AXA69_004535	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
AXA69_004545	COG1051	belongs to the nudix hydrolase family
AXA69_004550	COG3066	DNA modification
AXA69_004560	COG0335	large ribosomal subunit rRNA binding
AXA69_004565	COG0336	Belongs to the RNA methyltransferase TrmD family
AXA69_004570	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
AXA69_004575	COG0228	four-way junction DNA binding
AXA69_004580	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
AXA69_004585	COG4137	Cytochrome C assembly protein
AXA69_004590	COG4536	flavin adenine dinucleotide binding
AXA69_004595	COG1959	2 iron, 2 sulfur cluster binding
AXA69_004600	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AXA69_004600	COG1017	nitric oxide dioxygenase activity
AXA69_004605	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
AXA69_004610	COG0039	L-malate dehydrogenase activity
AXA69_004615	COG4160	amino acid transport
AXA69_004620	COG4215	(ABC) transporter
AXA69_004625	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AXA69_004630	COG1126	abc transporter atp-binding protein
AXA69_004635	COG1438	arginine binding
AXA69_004640	COG2837	iron assimilation
AXA69_004645	COG3842	ATPase activity
AXA69_004655	COG1840	ABC-type Fe3 transport system, periplasmic component
AXA69_004660	COG0347	Belongs to the P(II) protein family
AXA69_004675	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
AXA69_004695	COG1929	Belongs to the glycerate kinase type-1 family
AXA69_004700	COG2610	gluconate transmembrane transporter activity
AXA69_004700	COG2610	gluconate transmembrane transporter activity
AXA69_004705	COG3835	regulator
AXA69_004710	COG3112	Uncharacterised protein family (UPF0231)
AXA69_004725	COG0840	transmembrane signaling receptor activity
AXA69_004730	COG3568	Endonuclease Exonuclease Phosphatase
AXA69_004745	COG0513	Belongs to the DEAD box helicase family
AXA69_004785	COG1448	Aminotransferase
AXA69_004800	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
AXA69_004805	COG1328	CTP reductase activity
AXA69_004840	COG1215	transferase activity, transferring glycosyl groups
AXA69_004880	COG0840	transmembrane signaling receptor activity
AXA69_004885	COG3397	chitin binding
AXA69_004890	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AXA69_004895	COG1126	abc transporter atp-binding protein
AXA69_004905	COG0765	amino acid transport
AXA69_004910	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
AXA69_004915	COG0583	DNA-binding transcription factor activity
AXA69_004920	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
AXA69_004925	COG4208	sulfate ABC transporter
AXA69_004930	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
AXA69_004940	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
AXA69_004945	COG3174	membrane
AXA69_004950	COG0110	maltose O-acetyltransferase activity
AXA69_004980	COG1942	4-Oxalocrotonate Tautomerase
AXA69_004990	COG0583	DNA-binding transcription factor activity
AXA69_004995	COG0165	Argininosuccinate lyase
AXA69_005000	COG0137	argininosuccinate synthase activity
AXA69_005010	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
AXA69_005015	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
AXA69_005025	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
AXA69_005035	COG2072	flavoprotein involved in K transport
AXA69_005040	COG1393	Belongs to the ArsC family
AXA69_005045	COG0798	PFAM Bile acid sodium symporter
AXA69_005065	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
AXA69_005085	COG3068	Protein conserved in bacteria
AXA69_005095	COG0739	heme binding
AXA69_005115	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
AXA69_005120	COG1121	(ABC) transporter
AXA69_005125	COG1108	ABC-type Mn2 Zn2 transport systems permease components
AXA69_005130	COG0583	DNA-binding transcription factor activity
AXA69_005140	COG1573	uracil-dna glycosylase
AXA69_005145	COG2962	Rard protein
AXA69_005155	COG2827	Endonuclease containing a URI domain
AXA69_005170	COG1842	Phage shock protein A
AXA69_005175	COG0204	Acyl-transferase
AXA69_005195	COG3118	belongs to the thioredoxin family
AXA69_005200	COG2259	Doxx family
AXA69_005255	COG1051	belongs to the nudix hydrolase family
AXA69_005260	COG3150	esterase
AXA69_005270	COG3151	Protein conserved in bacteria
AXA69_005275	COG0494	nUDIX hydrolase
AXA69_005285	COG1538	Outer membrane efflux protein
AXA69_005290	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
AXA69_005290	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
AXA69_005295	COG1560	Kdo2-lipid A biosynthetic process
AXA69_005310	COG1392	Phosphate transport regulator
AXA69_005315	COG0306	phosphate transporter
AXA69_005320	COG0617	tRNA 3'-terminal CCA addition
AXA69_005325	COG3267	Type II secretory pathway component ExeA
AXA69_005325	COG3409	Peptidoglycan-binding domain 1 protein
AXA69_005335	COG1194	a g-specific adenine glycosylase
AXA69_005340	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
AXA69_005350	COG3111	PFAM Bacterial OB fold (BOF) protein
AXA69_005355	COG3240	lipase activity
AXA69_005370	COG3009	Protein conserved in bacteria
AXA69_005375	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
AXA69_005375	COG3008	intermembrane lipid transfer
AXA69_005380	COG2995	paraquat-inducible protein a
AXA69_005390	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AXA69_005405	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AXA69_005410	COG2813	Specifically methylates the guanine in position
AXA69_005415	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
AXA69_005420	COG0297	glycogen (starch) synthase activity
AXA69_005460	COG1757	Na H antiporter
AXA69_005470	COG0110	maltose O-acetyltransferase activity
AXA69_005475	COG0366	Alpha amylase catalytic
AXA69_005495	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
AXA69_005500	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
AXA69_005505	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
AXA69_005510	COG2723	6-phospho-beta-galactosidase activity
AXA69_005515	COG1447	Phosphotransferase system cellobiose-specific component IIA
AXA69_005520	COG1940	carbohydrate kinase activity
AXA69_005530	COG1609	Transcriptional regulator
AXA69_005540	COG0252	asparaginase activity
AXA69_005555	COG1803	Methylglyoxal synthase
AXA69_005580	COG1444	tRNA N-acetyltransferase activity
AXA69_005585	COG1028	Short-chain dehydrogenase reductase Sdr
AXA69_005590	COG0835	chemotaxis
AXA69_005590	COG0784	Response regulator, receiver
AXA69_005700	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
AXA69_005705	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
AXA69_005720	COG0477	Major facilitator Superfamily
AXA69_005725	COG0523	cobalamin synthesis protein
AXA69_005735	COG1280	lysine exporter protein (LysE YggA)
AXA69_005745	COG0583	DNA-binding transcription factor activity
AXA69_005750	COG1028	Short-chain dehydrogenase reductase Sdr
AXA69_005755	COG2200	EAL domain
AXA69_005760	COG1049	propionate catabolic process, 2-methylcitrate cycle
AXA69_005775	COG0840	transmembrane signaling receptor activity
AXA69_005785	COG3447	MASE1 domain protein
AXA69_005785	COG5001	Diguanylate cyclase
AXA69_005785	COG5002	protein histidine kinase activity
AXA69_005790	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AXA69_005795	COG0508	dehydrogenase complex catalyzes the overall conversion of
AXA69_005800	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
AXA69_005805	COG2186	Transcriptional regulator
AXA69_005830	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
AXA69_005840	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
AXA69_005850	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
AXA69_005855	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
AXA69_005860	COG0494	nUDIX hydrolase
AXA69_005870	COG0653	protein targeting
AXA69_005880	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
AXA69_005885	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
AXA69_005890	COG0849	cell division
AXA69_005895	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
AXA69_005900	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
AXA69_005905	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
AXA69_005910	COG0772	Belongs to the SEDS family
AXA69_005915	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
AXA69_005920	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
AXA69_005925	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
AXA69_005935	COG0768	penicillin binding
AXA69_005940	COG3116	cell division
AXA69_005945	COG0275	rRNA processing
AXA69_005950	COG2001	Belongs to the MraZ family
AXA69_005960	COG1388	LysM domain
AXA69_005960	COG0741	lytic transglycosylase activity
AXA69_005965	COG1360	Flagellar Motor Protein
AXA69_005970	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
AXA69_005975	COG1191	sigma factor activity
AXA69_006000	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
AXA69_006015	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
AXA69_006045	COG1706	bacterial-type flagellum-dependent cell motility
AXA69_006050	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
AXA69_006055	COG4786	Flagellar basal body rod
AXA69_006060	COG4786	Flagellar basal body rod
AXA69_006065	COG1749	Flagellar hook protein flgE
AXA69_006080	COG1815	bacterial-type flagellum-dependent cell motility
AXA69_006090	COG2747	anti-sigma28 factor FlgM
AXA69_006115	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
AXA69_006125	COG1677	Flagellar hook-basal body complex protein FliE
AXA69_006150	COG1987	bacterial-type flagellum assembly
AXA69_006175	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
AXA69_006180	COG3107	peptidoglycan biosynthetic process
AXA69_006190	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
AXA69_006195	COG2823	Periplasmic or secreted lipoprotein
AXA69_006200	COG2969	positive regulation of protein catabolic process
AXA69_006205	COG0625	glutathione transferase activity
AXA69_006210	COG2857	Cytochrome c1
AXA69_006215	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
AXA69_006220	COG0723	plastoquinol--plastocyanin reductase activity
AXA69_006225	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
AXA69_006230	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
AXA69_006235	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
AXA69_006245	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AXA69_006250	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AXA69_006285	COG3964	amidohydrolase
AXA69_006310	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
AXA69_006315	COG1660	Displays ATPase and GTPase activities
AXA69_006320	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
AXA69_006330	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
AXA69_006335	COG1137	ATPase activity
AXA69_006340	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
AXA69_006345	COG3117	lipopolysaccharide transmembrane transporter activity
AXA69_006350	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
AXA69_006355	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
AXA69_006355	COG0517	IMP dehydrogenase activity
AXA69_006360	COG1127	ABC transporter
AXA69_006365	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
AXA69_006370	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
AXA69_006375	COG2854	intermembrane phospholipid transfer
AXA69_006385	COG5007	Belongs to the BolA IbaG family
AXA69_006390	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
AXA69_006395	COG0312	modulator of DNA gyrase
AXA69_006400	COG3028	Belongs to the UPF0307 family
AXA69_006410	COG2926	Belongs to the UPF0265 family
AXA69_006435	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
AXA69_006440	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
AXA69_006445	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
AXA69_006450	COG0049	tRNA binding
AXA69_006455	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
AXA69_006460	COG2168	tRNA wobble position uridine thiolation
AXA69_006465	COG2923	Belongs to the DsrF TusC family
AXA69_006480	COG2964	Protein conserved in bacteria
AXA69_006485	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
AXA69_006490	COG0085	RNA polymerase activity
AXA69_006495	COG0222	ribosome binding
AXA69_006500	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
AXA69_006505	COG0081	regulation of translation
AXA69_006510	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
AXA69_006515	COG0250	Participates in transcription elongation, termination and antitermination
AXA69_006530	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
AXA69_006555	COG0812	UDP-N-acetylmuramate dehydrogenase activity
AXA69_006560	COG0569	domain protein
AXA69_006565	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
AXA69_006570	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
AXA69_006575	COG3005	denitrification pathway
AXA69_006580	COG0243	molybdopterin cofactor binding
AXA69_006590	COG2205	protein histidine kinase activity
AXA69_006595	COG0745	RESPONSE REGULATOR receiver
AXA69_006610	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
AXA69_006615	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
AXA69_006625	COG2204	response regulator
AXA69_006635	COG2205	protein histidine kinase activity
AXA69_006650	COG1028	Short-chain dehydrogenase reductase Sdr
AXA69_006655	COG0517	IMP dehydrogenase activity
AXA69_006655	COG0617	tRNA 3'-terminal CCA addition
AXA69_006655	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
AXA69_006670	COG1522	sequence-specific DNA binding
AXA69_006675	COG2502	aspartate--ammonia ligase
AXA69_006680	COG0542	response to heat
AXA69_006690	COG0564	pseudouridine synthase activity
AXA69_006695	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AXA69_006700	COG0446	pyridine nucleotide-disulphide oxidoreductase
AXA69_006710	COG3681	Belongs to the UPF0597 family
AXA69_006715	COG2964	Protein conserved in bacteria
AXA69_006725	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
AXA69_006730	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
AXA69_006735	COG1979	alcohol dehydrogenase
AXA69_006745	COG3040	lipid binding
AXA69_006755	COG0688	phosphatidylethanolamine metabolic process
AXA69_006770	COG0540	Belongs to the ATCase OTCase family
AXA69_006775	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
AXA69_006780	COG1438	arginine binding
AXA69_006785	COG1288	antiporter activity
AXA69_006790	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
AXA69_006840	COG1609	Transcriptional regulator
AXA69_006845	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
AXA69_006855	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
AXA69_006860	COG2017	converts alpha-aldose to the beta-anomer
AXA69_006865	COG0667	Aldo Keto reductase
AXA69_006870	COG1968	undecaprenyl-diphosphatase activity
AXA69_006880	COG1595	DNA-templated transcription, initiation
AXA69_006890	COG0018	arginyl-trna synthetase
AXA69_006900	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
AXA69_006905	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
AXA69_006920	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AXA69_006930	COG2116	formate transmembrane transporter activity
AXA69_006935	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
AXA69_006935	COG1648	precorrin-2 dehydrogenase activity
AXA69_006940	COG2239	Acts as a magnesium transporter
AXA69_006950	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
AXA69_006955	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
AXA69_006965	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
AXA69_006975	COG0514	ATP-dependent DNA helicase (RecQ)
AXA69_006980	COG2050	protein possibly involved in aromatic compounds catabolism
AXA69_006995	COG2258	MOSC domain
AXA69_007000	COG1177	transmembrane transport
AXA69_007005	COG1176	ABC-type spermidine putrescine transport system, permease component I
AXA69_007010	COG3842	ATPase activity
AXA69_007030	COG0174	glutamine synthetase
AXA69_007045	COG3045	CreA protein
AXA69_007050	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AXA69_007055	COG0443	Heat shock 70 kDa protein
AXA69_007070	COG0366	Alpha amylase catalytic
AXA69_007075	COG1086	Polysaccharide biosynthesis protein
AXA69_007095	COG1442	glycosyl transferase family 8
AXA69_007115	COG0318	PFAM AMP-dependent synthetase and ligase
AXA69_007135	COG1083	cytidylyl-transferase
AXA69_007145	COG2089	acid synthase
AXA69_007210	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
AXA69_007215	COG0745	RESPONSE REGULATOR receiver
AXA69_007220	COG2205	protein histidine kinase activity
AXA69_007230	COG0281	malic enzyme
AXA69_007235	COG0702	epimerase
AXA69_007240	COG0254	rRNA binding
AXA69_007245	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
AXA69_007255	COG1309	transcriptional regulator
AXA69_007275	COG0129	dihydroxy-acid dehydratase activity
AXA69_007285	COG3978	acetolactate synthase activity
AXA69_007300	COG0204	Acyl-transferase
AXA69_007305	COG1683	Conserved Protein
AXA69_007315	COG1335	isochorismatase
AXA69_007325	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
AXA69_007330	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
AXA69_007335	COG3639	organic phosphonate transmembrane transporter activity
AXA69_007340	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
AXA69_007345	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
AXA69_007355	COG3084	Protein conserved in bacteria
AXA69_007360	COG3706	GGDEF domain
AXA69_007360	COG2203	Gaf domain
AXA69_007360	COG5001	Diguanylate cyclase
AXA69_007360	COG4251	negative regulation of phosphorylation
AXA69_007375	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
AXA69_007385	COG1561	YicC-like family, N-terminal region
AXA69_007415	COG0438	transferase activity, transferring glycosyl groups
AXA69_007420	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AXA69_007435	COG1063	alcohol dehydrogenase
AXA69_007450	COG0210	DNA helicase
AXA69_007455	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
AXA69_007460	COG2166	iron-sulfur cluster assembly
AXA69_007465	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
AXA69_007495	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
AXA69_007500	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
AXA69_007505	COG1739	Uncharacterized protein family UPF0029
AXA69_007510	COG0006	proline dipeptidase activity
AXA69_007515	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AXA69_007520	COG1024	Enoyl-CoA hydratase
AXA69_007520	COG1250	3-hydroxyacyl-CoA dehydrogenase
AXA69_007525	COG0183	Belongs to the thiolase family
AXA69_007530	COG0745	RESPONSE REGULATOR receiver
AXA69_007535	COG2205	protein histidine kinase activity
AXA69_007550	COG0425	Belongs to the sulfur carrier protein TusA family
AXA69_007555	COG0251	oxidation-reduction process
AXA69_007560	COG2885	chlorophyll binding
AXA69_007565	COG2818	Glycosylase
AXA69_007570	COG0752	glycyl-tRNA synthetase alpha subunit
AXA69_007575	COG0751	glycine-tRNA ligase activity
AXA69_007585	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
AXA69_007595	COG2202	Pas domain
AXA69_007595	COG2200	EAL domain
AXA69_007595	COG2199	diguanylate cyclase activity
AXA69_007610	COG0814	amino acid
AXA69_007615	COG0348	domain, Protein
AXA69_007625	COG0446	pyridine nucleotide-disulphide oxidoreductase
AXA69_007630	COG0426	domain, Protein
AXA69_007630	COG1773	rubredoxin
AXA69_007635	COG3604	Transcriptional regulator
AXA69_007640	COG2188	Transcriptional regulator
AXA69_007655	COG1609	Transcriptional regulator
AXA69_007695	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AXA69_007720	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
AXA69_007735	COG3118	belongs to the thioredoxin family
AXA69_007740	COG0513	Belongs to the DEAD box helicase family
AXA69_007745	COG0248	Ppx GppA phosphatase
AXA69_007755	COG0742	ribosomal rna small subunit methyltransferase
AXA69_007760	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AXA69_007780	COG0084	hydrolase, TatD family'
AXA69_007785	COG0805	protein transport
AXA69_007790	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
AXA69_007800	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
AXA69_007805	COG3165	ubiquinone biosynthetic process from chorismate
AXA69_007815	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
AXA69_007860	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
AXA69_007865	COG0848	biopolymer transport protein
AXA69_007870	COG0811	peptide transport
AXA69_007875	COG0811	peptide transport
AXA69_007885	COG2771	luxR family
AXA69_007910	COG1484	DNA-dependent DNA replication
AXA69_007915	COG4584	PFAM Integrase catalytic
AXA69_007970	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
AXA69_007975	COG1349	DNA-binding transcription factor activity
AXA69_007980	COG0745	RESPONSE REGULATOR receiver
AXA69_007985	COG2205	protein histidine kinase activity
AXA69_007995	COG4452	Inner membrane protein CreD
AXA69_008000	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
AXA69_008005	COG0355	proton-transporting ATP synthase activity, rotational mechanism
AXA69_008010	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
AXA69_008015	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
AXA69_008020	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
AXA69_008025	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
AXA69_008030	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
AXA69_008040	COG0356	it plays a direct role in the translocation of protons across the membrane
AXA69_008045	COG3312	ion transport
AXA69_008050	COG1475	DNA binding
AXA69_008055	COG1192	Involved in chromosome partitioning
AXA69_008060	COG0357	Ribosomal RNA small subunit methyltransferase G
AXA69_008065	COG0445	tRNA wobble uridine modification
AXA69_008070	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
AXA69_008075	COG4774	siderophore transport
AXA69_008080	COG4615	Cyclic peptide transporter
AXA69_008085	COG1120	ATPase activity
AXA69_008090	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AXA69_008100	COG4774	siderophore transport
AXA69_008105	COG4607	ABC-type enterochelin transport system periplasmic component
AXA69_008110	COG4604	ABC transporter, ATP-binding protein
AXA69_008115	COG4605	iron ion homeostasis
AXA69_008120	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AXA69_008140	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AXA69_008165	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
AXA69_008170	COG0706	membrane insertase activity
AXA69_008175	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
AXA69_008180	COG0594	ribonuclease P activity
AXA69_008185	COG0230	Belongs to the bacterial ribosomal protein bL34 family
AXA69_008205	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
AXA69_008210	COG0592	DNA-directed DNA polymerase activity
AXA69_008235	COG2378	regulation of single-species biofilm formation
AXA69_008240	COG0071	Belongs to the small heat shock protein (HSP20) family
AXA69_008245	COG0071	Belongs to the small heat shock protein (HSP20) family
AXA69_008260	COG3977	Valine--pyruvate aminotransferase
AXA69_008285	COG0745	RESPONSE REGULATOR receiver
AXA69_008290	COG2205	protein histidine kinase activity
AXA69_008310	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AXA69_008315	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AXA69_008315	COG4191	Histidine kinase
AXA69_008320	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AXA69_008325	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AXA69_008330	COG1309	transcriptional regulator
AXA69_008360	COG0561	phosphatase activity
AXA69_008365	COG2267	carboxylic ester hydrolase activity
AXA69_008370	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AXA69_008375	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
AXA69_008380	COG1758	RNA polymerase activity
AXA69_008385	COG0194	GDP metabolic process
AXA69_008395	COG0859	PFAM glycosyl transferase family 9
AXA69_008400	COG3642	lipopolysaccharide core region biosynthetic process
AXA69_008435	COG0589	response to stress
AXA69_008440	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
AXA69_008450	COG1528	Iron-storage protein
AXA69_008455	COG2081	HI0933 family
AXA69_008495	COG4584	PFAM Integrase catalytic
AXA69_008500	COG1484	DNA-dependent DNA replication
AXA69_008515	COG2197	response regulator
AXA69_008520	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AXA69_008520	COG2205	protein histidine kinase activity
AXA69_008530	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AXA69_008530	COG2205	protein histidine kinase activity
AXA69_008540	COG3275	phosphorelay sensor kinase activity
AXA69_008545	COG3279	Response regulator of the LytR AlgR family
AXA69_008550	COG2223	nitrite transmembrane transporter activity
AXA69_008555	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
AXA69_008560	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
AXA69_008575	COG0583	DNA-binding transcription factor activity
AXA69_008580	COG4206	TonB-dependent receptor
AXA69_008585	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
AXA69_008630	COG0583	DNA-binding transcription factor activity
AXA69_008635	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
AXA69_008640	COG0166	Belongs to the GPI family
AXA69_008650	COG0668	transmembrane transport
AXA69_008655	COG1309	transcriptional regulator
AXA69_008660	COG0756	dUTP diphosphatase activity
AXA69_008665	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
AXA69_008670	COG2003	Belongs to the UPF0758 family
AXA69_008675	COG0227	Belongs to the bacterial ribosomal protein bL28 family
AXA69_008680	COG0267	Belongs to the bacterial ribosomal protein bL33 family
AXA69_008690	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
AXA69_008695	COG2990	Protein conserved in bacteria
AXA69_008700	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
AXA69_008705	COG0859	PFAM glycosyl transferase family 9
AXA69_008710	COG0463	Glycosyl transferase, family 2
AXA69_008715	COG0859	PFAM glycosyl transferase family 9
AXA69_008720	COG1519	Transferase
AXA69_008735	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
AXA69_008740	COG1609	Transcriptional regulator
AXA69_008755	COG1580	Controls the rotational direction of flagella during chemotaxis
AXA69_008760	COG3161	chorismate lyase activity
AXA69_008765	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
AXA69_008770	COG2937	Belongs to the GPAT DAPAT family
AXA69_008775	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
AXA69_008795	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
AXA69_008800	COG2205	protein histidine kinase activity
AXA69_008805	COG0745	RESPONSE REGULATOR receiver
AXA69_008815	COG1045	serine acetyltransferase
AXA69_008825	COG3074	FtsZ-dependent cytokinesis
AXA69_008830	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
AXA69_008845	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
AXA69_008895	COG0385	Bile acid
AXA69_008900	COG1262	PFAM Formylglycine-generating sulfatase enzyme
AXA69_008920	COG0583	DNA-binding transcription factor activity
AXA69_008945	COG0210	DNA helicase
AXA69_008980	COG2823	Periplasmic or secreted lipoprotein
AXA69_009000	COG0583	DNA-binding transcription factor activity
AXA69_009005	COG1280	lysine exporter protein (LysE YggA)
AXA69_009010	COG2391	methyltransferase activity
AXA69_009020	COG1280	lysine exporter protein (LysE YggA)
AXA69_009030	COG2962	Rard protein
AXA69_009035	COG1012	belongs to the aldehyde dehydrogenase family
AXA69_009055	COG0519	Catalyzes the synthesis of GMP from XMP
AXA69_009055	COG0518	GMP synthase (glutamine-hydrolyzing) activity
AXA69_009060	COG0686	Belongs to the AlaDH PNT family
AXA69_009065	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AXA69_009090	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
AXA69_009095	COG0569	domain protein
AXA69_009100	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
AXA69_009100	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
AXA69_009105	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
AXA69_009110	COG0242	peptide deformylase activity
AXA69_009115	COG1652	LysM domain
AXA69_009120	COG0758	DNA mediated transformation
AXA69_009125	COG2922	Belongs to the Smg family
AXA69_009130	COG0551	DNA topoisomerase type I activity
AXA69_009140	COG0009	L-threonylcarbamoyladenylate synthase
AXA69_009145	COG0408	coproporphyrinogen oxidase activity
AXA69_009150	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
AXA69_009160	COG0218	Necessary for normal cell division and for the maintenance of normal septation
AXA69_009170	COG3078	GTPase activator activity
AXA69_009180	COG0635	Involved in the biosynthesis of porphyrin-containing compound
AXA69_009185	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
AXA69_009190	COG2204	response regulator
AXA69_009195	COG3852	Histidine kinase
AXA69_009205	COG0174	glutamine synthetase
AXA69_009215	COG1295	ribonuclease BN
AXA69_009230	COG0456	acetyltransferase
AXA69_009240	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
AXA69_009245	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AXA69_009250	COG2610	gluconate transmembrane transporter activity
AXA69_009255	COG3265	gluconokinase activity
AXA69_009260	COG0129	dihydroxy-acid dehydratase activity
AXA69_009265	COG0800	Aldolase
AXA69_009270	COG1609	Transcriptional regulator
AXA69_009280	COG4942	peptidase
AXA69_009285	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
AXA69_009290	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AXA69_009295	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
AXA69_009300	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
AXA69_009305	COG0316	Belongs to the HesB IscA family
AXA69_009305	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
AXA69_009310	COG1040	competence protein
AXA69_009315	COG0596	Alpha beta hydrolase
AXA69_009335	COG2183	response to ionizing radiation
AXA69_009340	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
AXA69_009345	COG0745	RESPONSE REGULATOR receiver
AXA69_009360	COG0051	transcription antitermination factor activity, RNA binding
AXA69_009365	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
AXA69_009370	COG0088	Forms part of the polypeptide exit tunnel
AXA69_009375	COG0089	rRNA binding
AXA69_009380	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
AXA69_009385	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
AXA69_009390	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
AXA69_009395	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
AXA69_009400	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
AXA69_009405	COG0255	Belongs to the universal ribosomal protein uL29 family
AXA69_009410	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
AXA69_009415	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
AXA69_009420	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
AXA69_009425	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
AXA69_009430	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
AXA69_009435	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
AXA69_009440	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
AXA69_009445	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
AXA69_009450	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
AXA69_009455	COG1841	ribosomal large subunit assembly
AXA69_009460	COG0200	Binds to the 23S rRNA
AXA69_009465	COG0201	protein transport
AXA69_009470	COG0257	Belongs to the bacterial ribosomal protein bL36 family
AXA69_009475	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
AXA69_009480	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
AXA69_009485	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
AXA69_009490	COG0202	RNA polymerase activity
AXA69_009495	COG0203	ribosomal protein L17
AXA69_009545	COG1484	DNA-dependent DNA replication
AXA69_009550	COG4584	PFAM Integrase catalytic
AXA69_009560	COG2376	Dihydroxyacetone kinase
AXA69_009565	COG1461	Dihydroxyacetone kinase
AXA69_009570	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
AXA69_009570	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
AXA69_009570	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
AXA69_009580	COG3284	Transcriptional regulator
AXA69_009585	COG0628	permease
AXA69_009590	COG0494	nUDIX hydrolase
AXA69_009615	COG0753	catalase activity
AXA69_009640	COG2199	diguanylate cyclase activity
AXA69_009640	COG2203	Gaf domain
AXA69_009650	COG3842	ATPase activity
AXA69_009660	COG1176	ABC-type spermidine putrescine transport system, permease component I
AXA69_009695	COG1741	Belongs to the pirin family
AXA69_009700	COG2259	Doxx family
AXA69_009705	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
AXA69_009710	COG1074	ATP-dependent DNA helicase activity
AXA69_009715	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
AXA69_009725	COG0346	lactoylglutathione lyase activity
AXA69_009740	COG0004	ammonium transporteR
AXA69_009745	COG0347	Belongs to the P(II) protein family
AXA69_009760	COG0840	transmembrane signaling receptor activity
AXA69_009780	COG0745	RESPONSE REGULATOR receiver
AXA69_009785	COG2205	protein histidine kinase activity
AXA69_009790	COG3706	GGDEF domain
AXA69_009795	COG4771	TonB-dependent receptor
AXA69_009800	COG1278	Cold shock
AXA69_009810	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
AXA69_009815	COG2197	response regulator
AXA69_009830	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
AXA69_009865	COG2249	NAD(P)H dehydrogenase (quinone) activity
AXA69_009880	COG1770	oligopeptidase
AXA69_009895	COG3714	YhhN family
AXA69_009920	COG1301	dicarboxylic acid transport
AXA69_009930	COG2095	MarC family integral membrane protein
AXA69_009940	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
AXA69_009950	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
AXA69_009955	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AXA69_009985	COG0742	ribosomal rna small subunit methyltransferase
AXA69_009990	COG0552	protein localization to endoplasmic reticulum
AXA69_009995	COG2884	Cell division ATP-binding protein ftsE
AXA69_010000	COG2177	Part of the ABC transporter FtsEX involved in
AXA69_010010	COG0288	reversible hydration of carbon dioxide
AXA69_010015	COG2188	Transcriptional regulator
AXA69_010020	COG1228	amidohydrolase
AXA69_010025	COG0010	Belongs to the arginase family
AXA69_010030	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
AXA69_010035	COG2986	histidine ammonia-lyase
AXA69_010040	COG0387	Pfam Sodium calcium exchanger
AXA69_010045	COG2264	protein methyltransferase activity
AXA69_010050	COG2200	EAL domain
AXA69_010050	COG2199	diguanylate cyclase activity
AXA69_010110	COG1077	Cell shape determining protein MreB Mrl
AXA69_010115	COG1792	Involved in formation and maintenance of cell shape
AXA69_010120	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
AXA69_010125	COG0424	maF-like protein
AXA69_010130	COG1530	ribonuclease E activity
AXA69_010135	COG3164	Protein of unknown function
AXA69_010145	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AXA69_010150	COG0312	modulator of DNA gyrase
AXA69_010175	COG3437	response regulator, receiver
AXA69_010180	COG0784	Response regulator, receiver
AXA69_010180	COG2205	protein histidine kinase activity
AXA69_010180	COG5002	protein histidine kinase activity
AXA69_010185	COG2172	sigma factor antagonist activity
AXA69_010190	COG1366	Belongs to the anti-sigma-factor antagonist family
AXA69_010200	COG3700	Belongs to the class B bacterial acid phosphatase family
AXA69_010210	COG1639	'signal transduction protein
AXA69_010230	COG0189	ligase activity
AXA69_010235	COG0642	Histidine kinase
AXA69_010240	COG0745	RESPONSE REGULATOR receiver
AXA69_010260	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
AXA69_010265	COG0352	thiamine-phosphate diphosphorylase activity
AXA69_010270	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
AXA69_010280	COG2022	thiamine diphosphate biosynthetic process
AXA69_010310	COG0110	maltose O-acetyltransferase activity
AXA69_010315	COG3417	Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1B (PBP1b)
AXA69_010330	COG0814	amino acid
AXA69_010335	COG3932	Exopolysaccharide synthesis, ExoD
AXA69_010385	COG1494	fructose-1,6-bisphosphatase
AXA69_010400	COG2959	enzyme of heme biosynthesis
AXA69_010410	COG0181	hydroxymethylbilane synthase activity
AXA69_010415	COG3072	Adenylate cyclase
AXA69_010435	COG1965	Belongs to the frataxin family
AXA69_010445	COG0019	diaminopimelate decarboxylase activity
AXA69_010450	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
AXA69_010465	COG1011	Hydrolase
AXA69_010475	COG0668	transmembrane transport
AXA69_010485	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
AXA69_010490	COG0561	phosphatase activity
AXA69_010505	COG1129	ABC transporter
AXA69_010505	COG0842	Transport permease protein
AXA69_010515	COG1058	Belongs to the CinA family
AXA69_010515	COG1546	Belongs to the CinA family
AXA69_010520	COG1418	mRNA catabolic process
AXA69_010525	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
AXA69_010535	COG1522	sequence-specific DNA binding
AXA69_010540	COG1368	sulfuric ester hydrolase activity
AXA69_010560	COG1285	pathogenesis
AXA69_010580	COG4221	oxidoreductase activity
AXA69_010600	COG1979	alcohol dehydrogenase
AXA69_010610	COG2873	o-acetylhomoserine
AXA69_010615	COG4533	DNA binding
AXA69_010620	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
AXA69_010635	COG5380	lipid catabolic process
AXA69_010640	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
AXA69_010650	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
AXA69_010655	COG2949	membrane
AXA69_010660	COG3291	Pkd domain containing protein
AXA69_010670	COG3539	Fimbrial protein
AXA69_010680	COG3188	usher protein
AXA69_010685	COG3121	Chaperone
AXA69_010690	COG3539	Fimbrial protein
AXA69_010705	COG0318	PFAM AMP-dependent synthetase and ligase
AXA69_010715	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
AXA69_010720	COG0596	Alpha beta hydrolase
AXA69_010725	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
AXA69_010730	COG1169	isochorismate synthase
AXA69_010735	COG1575	Belongs to the MenA family. Type 1 subfamily
AXA69_010760	COG0513	Belongs to the DEAD box helicase family
AXA69_010765	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
AXA69_010770	COG1988	membrane-bound metal-dependent
AXA69_010785	COG1671	Belongs to the UPF0178 family
AXA69_010805	COG0484	heat shock protein binding
AXA69_010810	COG3263	regulation of cellular component size
AXA69_010815	COG3722	fumarate hydratase activity
AXA69_010820	COG0246	Mannitol dehydrogenase
AXA69_010825	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
AXA69_010825	COG2213	PTS system mannitol-specific
AXA69_010840	COG4776	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction
AXA69_010855	COG2771	luxR family
AXA69_010870	COG3133	Outer membrane lipoprotein
AXA69_010875	COG0456	acetyltransferase
AXA69_010895	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
AXA69_010900	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
AXA69_010920	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
AXA69_010925	COG1459	type II secretion system
AXA69_010930	COG2165	general secretion pathway protein
AXA69_010940	COG2165	general secretion pathway protein
AXA69_010945	COG4795	General secretion pathway protein
AXA69_010950	COG3156	type II secretion system protein K
AXA69_010960	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
AXA69_010975	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
AXA69_010980	COG1011	Hydrolase
AXA69_010985	COG0494	nUDIX hydrolase
AXA69_010990	COG1218	3'(2'),5'-bisphosphate nucleotidase
AXA69_010995	COG0814	amino acid
AXA69_011000	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AXA69_011015	COG0626	cystathionine gamma-synthase activity
AXA69_011020	COG0527	aspartate kinase activity
AXA69_011020	COG0460	homoserine dehydrogenase
AXA69_011035	COG1346	cytolysis
AXA69_011040	COG1380	Effector of murein hydrolase LrgA
AXA69_011075	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
AXA69_011080	COG1546	Belongs to the CinA family
AXA69_011085	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
AXA69_011095	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
AXA69_011100	COG0527	aspartate kinase activity
AXA69_011105	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
AXA69_011130	COG1686	Belongs to the peptidase S11 family
AXA69_011135	COG0586	Pfam SNARE associated Golgi protein
AXA69_011140	COG1253	flavin adenine dinucleotide binding
AXA69_011150	COG2927	DNA polymerase III (CHI subunit)
AXA69_011155	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
AXA69_011160	COG0795	lipopolysaccharide-transporting ATPase activity
AXA69_011165	COG0795	lipopolysaccharide-transporting ATPase activity
AXA69_011305	COG4695	Portal protein
AXA69_011390	COG2932	Transcriptional regulator
AXA69_011395	COG4974	Belongs to the 'phage' integrase family
AXA69_011400	COG0582	viral genome integration into host DNA
AXA69_011420	COG3561	AntA/AntB antirepressor
AXA69_011465	COG0004	ammonium transporteR
AXA69_011470	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
AXA69_011490	COG0084	hydrolase, TatD family'
AXA69_011495	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
AXA69_011505	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
AXA69_011510	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
AXA69_011515	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
AXA69_011520	COG0813	purine-nucleoside phosphorylase activity
AXA69_011530	COG0560	Phosphoserine phosphatase
AXA69_011555	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
AXA69_011560	COG0776	regulation of translation
AXA69_011570	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
AXA69_011575	COG0735	belongs to the Fur family
AXA69_011595	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
AXA69_011600	COG0513	Belongs to the DEAD box helicase family
AXA69_011605	COG3022	response to hydroperoxide
AXA69_011620	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
AXA69_011625	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
AXA69_011630	COG0762	integral membrane protein
AXA69_011635	COG1872	DUF167
AXA69_011650	COG4166	transmembrane transport
AXA69_011660	COG0110	maltose O-acetyltransferase activity
AXA69_011670	COG1024	Enoyl-CoA hydratase
AXA69_011685	COG4221	oxidoreductase activity
AXA69_011695	COG2957	Belongs to the agmatine deiminase family
AXA69_011720	COG0513	Belongs to the DEAD box helicase family
AXA69_011740	COG1912	Pfam S-adenosyl-l-methionine hydroxide adenosyltransferase
AXA69_011805	COG2816	NAD+ diphosphatase activity
AXA69_011810	COG2205	protein histidine kinase activity
AXA69_011815	COG0745	RESPONSE REGULATOR receiver
AXA69_011820	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AXA69_011825	COG0577	efflux transmembrane transporter activity
AXA69_011825	COG1136	(ABC) transporter
AXA69_011830	COG1505	serine-type exopeptidase activity
AXA69_011835	COG2982	Protein involved in outer membrane biogenesis
AXA69_011860	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
AXA69_011865	COG3730	PTS system glucitol sorbitol-specific
AXA69_011880	COG1028	Short-chain dehydrogenase reductase Sdr
AXA69_011890	COG1349	DNA-binding transcription factor activity
AXA69_011895	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
AXA69_011910	COG0494	nUDIX hydrolase
AXA69_011915	COG2130	NADP-dependent
AXA69_011920	COG1764	response to oxidative stress
AXA69_011925	COG1846	Transcriptional regulator
AXA69_011955	COG0561	phosphatase activity
AXA69_011970	COG0733	neurotransmitter:sodium symporter activity
AXA69_011980	COG0733	neurotransmitter:sodium symporter activity
AXA69_012020	COG1794	racemase activity, acting on amino acids and derivatives
AXA69_012030	COG2731	YhcH YjgK YiaL family protein
AXA69_012040	COG0668	transmembrane transport
AXA69_012045	COG1376	ErfK ybiS ycfS ynhG family protein
AXA69_012050	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AXA69_012060	COG0789	Transcriptional regulator
AXA69_012130	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
AXA69_012140	COG0488	(ABC) transporter
AXA69_012145	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
AXA69_012145	COG0517	IMP dehydrogenase activity
AXA69_012150	COG1585	Membrane protein implicated in regulation of membrane protease activity
AXA69_012155	COG0330	HflC and HflK could
AXA69_012160	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
AXA69_012160	COG1648	precorrin-2 dehydrogenase activity
AXA69_012165	COG0175	sulfate reduction
AXA69_012170	COG2895	sulfate adenylyltransferase (ATP) activity
AXA69_012175	COG0471	metal ion transport
AXA69_012175	COG3273	potassium ion transport
AXA69_012180	COG0529	Catalyzes the synthesis of activated sulfate
AXA69_012195	COG0840	transmembrane signaling receptor activity
AXA69_012215	COG1136	(ABC) transporter
AXA69_012230	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
AXA69_012245	COG1940	carbohydrate kinase activity
AXA69_012250	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
AXA69_012255	COG0126	phosphoglycerate kinase activity
AXA69_012260	COG0191	fructose-bisphosphate aldolase activity
AXA69_012265	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AXA69_012315	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
AXA69_012320	COG1595	DNA-templated transcription, initiation
AXA69_012325	COG3073	An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E
AXA69_012340	COG0481	GTPase activity
AXA69_012350	COG0571	ribonuclease III activity
AXA69_012360	COG1381	Involved in DNA repair and RecF pathway recombination
AXA69_012365	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
AXA69_012370	COG3023	N-Acetylmuramoyl-L-alanine amidase
AXA69_012375	COG4807	Protein conserved in bacteria
AXA69_012385	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
AXA69_012390	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
AXA69_012395	COG3956	TIGRFAM MazG family protein
AXA69_012400	COG0504	CTP synthase activity
AXA69_012405	COG0148	phosphopyruvate hydratase activity
AXA69_012410	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
AXA69_012415	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
AXA69_012425	COG0585	pseudouridine synthase activity
AXA69_012430	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
AXA69_012435	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
AXA69_012440	COG1238	metal cluster binding
AXA69_012445	COG1388	LysM domain
AXA69_012445	COG4942	peptidase
AXA69_012455	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
AXA69_012460	COG0828	Belongs to the bacterial ribosomal protein bS21 family
AXA69_012465	COG1610	YqeY-like protein
AXA69_012475	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
AXA69_012515	COG0151	Belongs to the GarS family
AXA69_012520	COG0138	bifunctional purine biosynthesis protein purh
AXA69_012530	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
AXA69_012535	COG3036	rescue of stalled ribosome
AXA69_012540	COG0635	Involved in the biosynthesis of porphyrin-containing compound
AXA69_012545	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
AXA69_012570	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AXA69_012575	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AXA69_012590	COG0477	Major facilitator Superfamily
AXA69_012600	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
AXA69_012605	COG1027	Aspartate ammonia-lyase
AXA69_012610	COG3030	protein affecting phage T7 exclusion by the F plasmid
AXA69_012615	COG0534	Mate efflux family protein
AXA69_012620	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
AXA69_012625	COG0459	protein refolding
AXA69_012635	COG3300	MHYT domain
AXA69_012635	COG5001	Diguanylate cyclase
AXA69_012645	COG0564	pseudouridine synthase activity
AXA69_012650	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
AXA69_012680	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AXA69_012690	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
AXA69_012695	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
AXA69_012700	COG1178	ABC-type Fe3 transport system permease component
AXA69_012705	COG4143	(ABC) transporter
AXA69_012720	COG0066	3-isopropylmalate dehydratase activity
AXA69_012725	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
AXA69_012730	COG0473	3-isopropylmalate dehydrogenase activity
AXA69_012735	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AXA69_012745	COG0671	phosphoesterase, PA-phosphatase related
AXA69_012755	COG0028	Belongs to the TPP enzyme family
AXA69_012760	COG0440	acetolactate synthase activity
AXA69_012765	COG0857	belongs to the CobB CobQ family
AXA69_012765	COG0280	phosphate acetyltransferase
AXA69_012770	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
AXA69_012780	COG3013	Belongs to the UPF0304 family
AXA69_012785	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
AXA69_012790	COG2716	regulation of RNA biosynthetic process
AXA69_012800	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
AXA69_012805	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
AXA69_012840	COG0784	Response regulator, receiver
AXA69_012840	COG5002	protein histidine kinase activity
AXA69_012840	COG2198	Histidine kinase
AXA69_012865	COG0840	transmembrane signaling receptor activity
AXA69_012875	COG1464	Belongs to the NlpA lipoprotein family
AXA69_012880	COG2011	ABC-type metal ion transport system permease component
AXA69_012910	COG0802	atpase or kinase
AXA69_012920	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
AXA69_012925	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
AXA69_012930	COG1923	regulation of RNA biosynthetic process
AXA69_012935	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
AXA69_012940	COG0330	HflC and HflK could
AXA69_012945	COG0330	HflC and HflK could
AXA69_012950	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
AXA69_012955	COG0142	geranyltranstransferase activity
AXA69_012960	COG0261	This protein binds to 23S rRNA in the presence of protein L20
AXA69_012965	COG0211	Belongs to the bacterial ribosomal protein bL27 family
AXA69_012970	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
AXA69_012990	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
AXA69_013000	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AXA69_013015	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
AXA69_013020	COG2967	ApaG domain
AXA69_013025	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
AXA69_013030	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
AXA69_013040	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
AXA69_013045	COG3178	'Phosphotransferase
AXA69_013050	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
AXA69_013055	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
AXA69_013070	COG0488	(ABC) transporter
AXA69_013095	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AXA69_013105	COG3721	Heme iron utilization protein
AXA69_013110	COG0748	coenzyme F420 binding
AXA69_013130	COG4771	TonB-dependent receptor
AXA69_013135	COG2814	Major facilitator Superfamily
AXA69_013145	COG3655	Transcriptional regulator
AXA69_013170	COG3397	chitin binding
AXA69_013185	COG1765	OsmC-like protein
AXA69_013200	COG3954	Phosphoribulokinase
AXA69_013205	COG2076	Multidrug Resistance protein
AXA69_013210	COG2076	Multidrug Resistance protein
AXA69_013215	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
AXA69_013220	COG0726	polysaccharide deacetylase
AXA69_013230	COG0463	Glycosyl transferase, family 2
AXA69_013235	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
AXA69_013245	COG3089	Belongs to the UPF0270 family
AXA69_013250	COG4251	negative regulation of phosphorylation
AXA69_013250	COG2203	Gaf domain
AXA69_013250	COG3706	GGDEF domain
AXA69_013250	COG5001	Diguanylate cyclase
AXA69_013255	COG0429	hydrolase of the alpha beta-hydrolase fold
AXA69_013260	COG0784	Response regulator, receiver
AXA69_013260	COG0835	chemotaxis
AXA69_013270	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
AXA69_013275	COG1047	Peptidyl-prolyl cis-trans
AXA69_013290	COG0545	Peptidyl-prolyl cis-trans isomerase
AXA69_013295	COG2204	response regulator
AXA69_013315	COG0737	Belongs to the 5'-nucleotidase family
AXA69_013335	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
AXA69_013340	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
AXA69_013350	COG2203	Gaf domain
AXA69_013350	COG2200	EAL domain
AXA69_013350	COG2199	diguanylate cyclase activity
AXA69_013405	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
AXA69_013410	COG2201	protein-glutamate methylesterase activity
AXA69_013415	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
AXA69_013425	COG0840	transmembrane signaling receptor activity
AXA69_013430	COG0835	chemotaxis
AXA69_013440	COG0643	Histidine kinase
AXA69_013440	COG2198	Histidine kinase
AXA69_013450	COG0745	RESPONSE REGULATOR receiver
AXA69_013460	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AXA69_013470	COG1280	lysine exporter protein (LysE YggA)
AXA69_013485	COG3813	Protein conserved in bacteria
AXA69_013495	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
AXA69_013510	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
AXA69_013535	COG0300	oxidoreductase activity
AXA69_013555	COG2133	pyrroloquinoline quinone binding
AXA69_013580	COG0077	Prephenate dehydratase
AXA69_013580	COG1605	Chorismate mutase
AXA69_013610	COG3272	Protein of unknown function (DUF1722)
AXA69_013615	COG0789	Transcriptional regulator
AXA69_013620	COG0415	Belongs to the DNA photolyase family
AXA69_013630	COG0300	oxidoreductase activity
AXA69_013645	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
AXA69_013670	COG0783	Belongs to the Dps family
AXA69_013675	COG1151	hydroxylamine reductase activity
AXA69_013685	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
AXA69_013690	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
AXA69_013690	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
AXA69_013700	COG3459	Glycosyltransferase 36 associated
AXA69_013725	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
AXA69_013730	COG1666	GTP binding
AXA69_013735	COG3248	Nucleoside-binding outer membrane protein
AXA69_013740	COG2211	Major facilitator Superfamily
AXA69_013750	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
AXA69_013760	COG2813	Specifically methylates the guanine in position
AXA69_013765	COG0271	Belongs to the BolA IbaG family
AXA69_013775	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
AXA69_013780	COG1805	sodium ion transport
AXA69_013785	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
AXA69_013790	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
AXA69_013795	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
AXA69_013800	COG2871	sodium ion transport
AXA69_013805	COG1477	protein flavinylation
AXA69_013820	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
AXA69_013825	COG0840	transmembrane signaling receptor activity
AXA69_013830	COG0583	DNA-binding transcription factor activity
AXA69_013840	COG2363	Small membrane protein
AXA69_013845	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
AXA69_013855	COG0473	3-isopropylmalate dehydrogenase activity
AXA69_013860	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AXA69_013865	COG1611	Belongs to the LOG family
AXA69_013870	COG3706	GGDEF domain
AXA69_013880	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
AXA69_013880	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
AXA69_013890	COG5595	Zn-ribbon-containing, possibly nucleic-acid-binding protein (DUF2310)
AXA69_013915	COG3098	single-species biofilm formation
AXA69_013920	COG0564	pseudouridine synthase activity
AXA69_013930	COG4580	involved in the transport of maltose and maltodextrins
AXA69_013950	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AXA69_013950	COG1263	PTS System
AXA69_013960	COG2171	N-acyltransferase activity
AXA69_013965	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
AXA69_013970	COG0024	Methionine aminopeptidase
AXA69_013975	COG0052	Belongs to the universal ribosomal protein uS2 family
AXA69_013980	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
AXA69_013985	COG0528	UMP kinase activity
AXA69_013990	COG0233	cytoplasmic translational termination
AXA69_013995	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
AXA69_014000	COG0575	Belongs to the CDS family
AXA69_014005	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
AXA69_014010	COG0750	zinc metalloprotease
AXA69_014025	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AXA69_014030	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
AXA69_014035	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AXA69_014040	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AXA69_014045	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
AXA69_014055	COG0825	malonyl-CoA metabolic process
AXA69_014060	COG3710	Transcriptional regulator
AXA69_014065	COG0531	amino acid
AXA69_014070	COG1982	Orn Lys Arg decarboxylase major
AXA69_014075	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
AXA69_014090	COG0814	amino acid
AXA69_014095	COG0531	amino acid
AXA69_014105	COG0488	(ABC) transporter
AXA69_014115	COG3590	peptidase
AXA69_014120	COG0037	tRNA processing
AXA69_014125	COG3706	GGDEF domain
AXA69_014180	COG1881	PFAM PEBP family protein
AXA69_014190	COG0583	DNA-binding transcription factor activity
AXA69_014200	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
AXA69_014210	COG0583	DNA-binding transcription factor activity
AXA69_014215	COG1028	Short-chain dehydrogenase reductase Sdr
AXA69_014220	COG0616	signal peptide processing
AXA69_014225	COG3724	N-succinylarginine dihydrolase activity
AXA69_014240	COG0840	transmembrane signaling receptor activity
AXA69_014250	COG2971	BadF BadG BcrA BcrD
AXA69_014260	COG4608	Belongs to the ABC transporter superfamily
AXA69_014265	COG0444	Belongs to the ABC transporter superfamily
AXA69_014270	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AXA69_014275	COG0601	transmembrane transport
AXA69_014285	COG2205	protein histidine kinase activity
AXA69_014285	COG0784	Response regulator, receiver
AXA69_014320	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
AXA69_014325	COG1289	transmembrane transporter activity
AXA69_014330	COG0303	'Molybdopterin
AXA69_014335	COG0746	molybdenum cofactor guanylyltransferase activity
AXA69_014345	COG4662	Binding-protein-dependent transport system inner membrane component
AXA69_014360	COG3852	Histidine kinase
AXA69_014370	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
AXA69_014375	COG2801	Transposase and inactivated derivatives
AXA69_014405	COG1196	nuclear chromosome segregation
AXA69_014405	COG3264	Mechanosensitive ion channel
AXA69_014410	COG0469	pyruvate kinase activity
AXA69_014425	COG4651	solute:proton antiporter activity
AXA69_014425	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
AXA69_014430	COG4651	solute:proton antiporter activity
AXA69_014430	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
AXA69_014435	COG0405	Gamma-glutamyltransferase
AXA69_014440	COG2974	May be involved in recombination
AXA69_014450	COG0420	3'-5' exonuclease activity
AXA69_014455	COG0419	ATPase involved in DNA repair
AXA69_014465	COG3038	cytochrome b561
AXA69_014475	COG3706	GGDEF domain
AXA69_014480	COG2190	(PTS) system
AXA69_014490	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
AXA69_014495	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
AXA69_014515	COG1720	tRNA m6t6A37 methyltransferase activity
AXA69_014535	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
AXA69_014540	COG4988	ABC transporter
AXA69_014555	COG0745	RESPONSE REGULATOR receiver
AXA69_014565	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
AXA69_014580	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
AXA69_014585	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
AXA69_014595	COG0083	homoserine kinase activity
AXA69_014600	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
AXA69_014630	COG1943	Transposase
AXA69_014650	COG0813	purine-nucleoside phosphorylase activity
AXA69_014665	COG3384	dioxygenase
AXA69_014675	COG1283	sodium-dependent phosphate transmembrane transporter activity
AXA69_014680	COG0531	amino acid
AXA69_014685	COG0531	amino acid
AXA69_014700	COG1396	sequence-specific DNA binding
AXA69_014700	COG1917	Cupin 2, conserved barrel domain protein
AXA69_014705	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AXA69_014715	COG1917	Cupin 2, conserved barrel domain protein
AXA69_014715	COG2169	Transcriptional regulator
AXA69_014740	COG2916	Histone family protein nucleoid-structuring protein H-NS
AXA69_014745	COG3328	transposase activity
AXA69_014755	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
AXA69_014760	COG2375	cellular response to nickel ion
AXA69_014765	COG1538	Outer membrane efflux protein
AXA69_014770	COG1136	(ABC) transporter
AXA69_014770	COG0577	efflux transmembrane transporter activity
AXA69_014775	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AXA69_014785	COG1227	inorganic diphosphatase activity
AXA69_014790	COG0497	DNA recombination
AXA69_014795	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
AXA69_014800	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
AXA69_014805	COG0443	Heat shock 70 kDa protein
AXA69_014810	COG0484	heat shock protein binding
AXA69_014840	COG1285	pathogenesis
AXA69_014885	COG0095	Lipoate-protein ligase
AXA69_014895	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AXA69_014900	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AXA69_014925	COG0708	Exodeoxyribonuclease III
AXA69_014980	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
AXA69_014985	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
AXA69_014990	COG1845	cytochrome c oxidase, subunit III
AXA69_014995	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
AXA69_015000	COG0109	protoheme IX farnesyltransferase activity
AXA69_015005	COG2814	Major facilitator Superfamily
AXA69_015025	COG1609	Transcriptional regulator
AXA69_015030	COG1263	PTS System
AXA69_015030	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AXA69_015035	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
AXA69_015060	COG2207	Transcriptional regulator
AXA69_015065	COG0538	isocitrate dehydrogenase activity
AXA69_015070	COG3048	D-serine ammonia-lyase activity
AXA69_015075	COG2610	gluconate transmembrane transporter activity
AXA69_015080	COG0583	DNA-binding transcription factor activity
AXA69_015160	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
AXA69_015165	COG2867	negative regulation of translational initiation
AXA69_015175	COG0702	epimerase
AXA69_015180	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AXA69_015210	COG4964	Belongs to the GSP D family
AXA69_015220	COG2894	cell division
AXA69_015260	COG1454	alcohol dehydrogenase
AXA69_015275	COG1957	nucleoside hydrolase
AXA69_015295	COG0840	transmembrane signaling receptor activity
AXA69_015300	COG1280	lysine exporter protein (LysE YggA)
AXA69_015320	COG3263	regulation of cellular component size
AXA69_015325	COG1876	peptidase activity
AXA69_015330	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AXA69_015335	COG1393	Belongs to the ArsC family
AXA69_015340	COG0583	DNA-binding transcription factor activity
AXA69_015355	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
AXA69_015360	COG0017	Asparaginyl-tRNA synthetase
AXA69_015380	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
AXA69_015385	COG0156	8-amino-7-oxononanoate synthase activity
AXA69_015390	COG1073	alpha beta
AXA69_015390	COG2226	methyltransferase
AXA69_015395	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
AXA69_015400	COG0501	Belongs to the peptidase M48B family
AXA69_015410	COG3217	Mosc domain protein beta barrel domain protein
AXA69_015410	COG3217	Mosc domain protein beta barrel domain protein
AXA69_015410	COG0633	Ferredoxin
AXA69_015410	COG0633	Ferredoxin
AXA69_015425	COG2841	Protein conserved in bacteria
AXA69_015435	COG0534	Mate efflux family protein
AXA69_015475	COG1309	transcriptional regulator
AXA69_015490	COG0791	NLP P60 protein
AXA69_015500	COG0583	DNA-binding transcription factor activity
AXA69_015510	COG0450	alkyl hydroperoxide reductase
AXA69_015530	COG0500	methyltransferase
AXA69_015535	COG4106	trans-aconitate 2-methyltransferase activity
AXA69_015545	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
AXA69_015550	COG0217	transcriptional regulatory protein
AXA69_015570	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AXA69_015580	COG4584	PFAM Integrase catalytic
AXA69_015585	COG1484	DNA-dependent DNA replication
AXA69_015610	COG0604	alcohol dehydrogenase
AXA69_015610	COG3321	synthase
AXA69_015625	COG0438	transferase activity, transferring glycosyl groups
AXA69_015655	COG1846	Transcriptional regulator
AXA69_015655	COG1940	carbohydrate kinase activity
AXA69_015660	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
AXA69_015665	COG0363	glucosamine-6-phosphate deaminase activity
AXA69_015670	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AXA69_015670	COG2190	(PTS) system
AXA69_015670	COG1263	PTS System
AXA69_015680	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AXA69_015685	COG0735	belongs to the Fur family
AXA69_015695	COG0716	FMN binding
AXA69_015710	COG0596	Alpha beta hydrolase
AXA69_015715	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
AXA69_015720	COG0033	Phosphoglucomutase
AXA69_015730	COG1846	Transcriptional regulator
AXA69_015735	COG2951	lytic endotransglycosylase activity
AXA69_015740	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
AXA69_015745	COG4136	ATPase activity
AXA69_015750	COG4135	transport system, permease component
AXA69_015755	COG4134	Bacterial extracellular solute-binding protein
AXA69_015760	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AXA69_015765	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AXA69_015775	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AXA69_015780	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AXA69_015795	COG0729	surface antigen
AXA69_015800	COG2911	Protein conserved in bacteria
AXA69_015815	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
AXA69_015840	COG1607	acyl-coa hydrolase
AXA69_015850	COG3021	interspecies interaction between organisms
AXA69_015855	COG0741	lytic transglycosylase activity
AXA69_015855	COG1388	LysM domain
AXA69_015860	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AXA69_015865	COG2226	methyltransferase
AXA69_015870	COG0328	RNA-DNA hybrid ribonuclease activity
AXA69_015875	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
AXA69_015885	COG3437	response regulator, receiver
AXA69_015885	COG0784	Response regulator, receiver
AXA69_015890	COG1960	acyl-CoA dehydrogenase activity
AXA69_015895	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
AXA69_015900	COG0121	glutamine amidotransferase
AXA69_015930	COG2197	response regulator
AXA69_015935	COG3850	Histidine kinase
AXA69_015940	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
AXA69_015945	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
AXA69_015955	COG0243	molybdopterin cofactor binding
AXA69_015960	COG0437	4 iron, 4 sulfur cluster binding
AXA69_015965	COG0348	domain, Protein
AXA69_015975	COG3005	denitrification pathway
AXA69_015980	COG0521	Mo-molybdopterin cofactor biosynthetic process
AXA69_015985	COG0315	cyclic pyranopterin monophosphate synthase activity
AXA69_015990	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
AXA69_015995	COG0314	molybdopterin synthase activity
AXA69_016010	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
AXA69_016040	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
AXA69_016050	COG0302	gtp cyclohydrolase
AXA69_016055	COG0840	transmembrane signaling receptor activity
AXA69_016060	COG2759	Belongs to the formate--tetrahydrofolate ligase family
AXA69_016070	COG0583	DNA-binding transcription factor activity
AXA69_016075	COG2353	YceI-like domain
AXA69_016100	COG2195	Cleaves the N-terminal amino acid of tripeptides
AXA69_016110	COG1166	arginine decarboxylase activity
AXA69_016140	COG0346	lactoylglutathione lyase activity
AXA69_016150	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
AXA69_016155	COG1187	pseudouridine synthase activity
AXA69_016160	COG2807	transmembrane transport
AXA69_016170	COG0583	DNA-binding transcription factor activity
AXA69_016190	COG2979	Protein of unknown function (DUF533)
AXA69_016195	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AXA69_016205	COG1294	oxidase, subunit
AXA69_016215	COG2814	Major facilitator Superfamily
AXA69_016220	COG0656	L-ascorbic acid biosynthetic process
AXA69_016225	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
AXA69_016250	COG0583	DNA-binding transcription factor activity
AXA69_016255	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
AXA69_016260	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
AXA69_016265	COG2271	Major facilitator Superfamily
AXA69_016270	COG1349	DNA-binding transcription factor activity
AXA69_016280	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
AXA69_016285	COG0584	glycerophosphoryl diester phosphodiesterase
AXA69_016290	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
AXA69_016295	COG0287	Prephenate dehydrogenase
AXA69_016295	COG1605	Chorismate mutase
AXA69_016305	COG3085	chromosome segregation
AXA69_016310	COG4574	serine-type endopeptidase inhibitor activity
AXA69_016330	COG1770	oligopeptidase
AXA69_016335	COG4771	TonB-dependent receptor
AXA69_016340	COG3083	sulfuric ester hydrolase activity
AXA69_016345	COG3082	Protein of unknown function (DUF1414)
AXA69_016350	COG3081	Nucleoid-associated protein
AXA69_016355	COG2182	Extracellular solute-binding protein
AXA69_016360	COG1175	transmembrane transport
AXA69_016365	COG3833	ABC-type maltose transport systems, permease component
AXA69_016370	COG3842	ATPase activity
AXA69_016385	COG0628	permease
AXA69_016390	COG0425	Belongs to the sulfur carrier protein TusA family
AXA69_016395	COG4783	chaperone-mediated protein folding
AXA69_016405	COG1393	Belongs to the ArsC family
AXA69_016415	COG3124	Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP
AXA69_016420	COG2431	L-lysine efflux transmembrane transporter activity
AXA69_016455	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
AXA69_016470	COG2373	Large extracellular alpha-helical protein
AXA69_016475	COG4953	penicillin-binding protein 1C
AXA69_016485	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AXA69_016485	COG0301	tRNA thio-modification
AXA69_016500	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
AXA69_016505	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
AXA69_016535	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AXA69_016545	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
AXA69_016565	COG0483	inositol monophosphate 1-phosphatase activity
AXA69_016575	COG0625	glutathione transferase activity
AXA69_016585	COG0601	transmembrane transport
AXA69_016590	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AXA69_016595	COG0444	Belongs to the ABC transporter superfamily
AXA69_016600	COG2814	Major facilitator Superfamily
AXA69_016605	COG0583	DNA-binding transcription factor activity
AXA69_016610	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
AXA69_016635	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AXA69_016640	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AXA69_016645	COG0404	The glycine cleavage system catalyzes the degradation of glycine
AXA69_016650	COG0509	glycine decarboxylation via glycine cleavage system
AXA69_016655	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
AXA69_016655	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
AXA69_016670	COG3634	alkyl hydroperoxide reductase activity
AXA69_016680	COG0517	IMP dehydrogenase activity
AXA69_016685	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
AXA69_016690	COG0343	queuine tRNA-ribosyltransferase activity
AXA69_016695	COG1862	Preprotein translocase
AXA69_016700	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AXA69_016705	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AXA69_016710	COG2897	thiosulfate sulfurtransferase activity
AXA69_016720	COG0826	peptidase U32
AXA69_016725	COG0826	peptidase U32
AXA69_016730	COG3154	lipid carrier protein
AXA69_016750	COG1104	cysteine desulfurase activity
AXA69_016755	COG0822	iron-sulfur transferase activity
AXA69_016765	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
AXA69_016770	COG0443	Heat shock 70 kDa protein
AXA69_016775	COG0633	Ferredoxin
AXA69_016785	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
AXA69_016790	COG0105	UTP biosynthetic process
AXA69_016795	COG0820	rRNA (adenine-C2-)-methyltransferase activity
AXA69_016805	COG1426	Protein conserved in bacteria
AXA69_016810	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
AXA69_016815	COG0124	histidyl-tRNA synthetase
AXA69_016820	COG2976	Protein conserved in bacteria
AXA69_016825	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AXA69_016830	COG1160	GTP binding
AXA69_016835	COG1645	bacterial-type flagellum-dependent swarming motility
AXA69_016840	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
AXA69_016845	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
AXA69_016845	COG0047	phosphoribosylformylglycinamidine synthase activity
AXA69_016855	COG2354	Protein conserved in bacteria
AXA69_016870	COG3150	esterase
AXA69_016875	COG1252	NADH dehydrogenase
AXA69_016880	COG0393	Putative heavy-metal-binding
AXA69_016890	COG1619	proteins homologs of microcin C7 resistance protein MccF
AXA69_016895	COG1368	sulfuric ester hydrolase activity
AXA69_016905	COG0527	aspartate kinase activity
AXA69_016910	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
AXA69_016910	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
AXA69_016915	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AXA69_016955	COG1285	pathogenesis
AXA69_017015	COG0672	)-iron permease
AXA69_017055	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
AXA69_017060	COG0574	Belongs to the PEP-utilizing enzyme family
AXA69_017060	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
AXA69_017100	COG1464	Belongs to the NlpA lipoprotein family
AXA69_017105	COG0671	phosphoesterase, PA-phosphatase related
AXA69_017110	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AXA69_017115	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
AXA69_017125	COG0101	tRNA pseudouridine synthase activity
AXA69_017130	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
AXA69_017135	COG0285	dihydrofolate synthase activity
AXA69_017140	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
AXA69_017145	COG2920	part of a sulfur-relay system
AXA69_017150	COG1289	transmembrane transporter activity
AXA69_017155	COG0670	Belongs to the BI1 family
AXA69_017165	COG0840	transmembrane signaling receptor activity
AXA69_017175	COG0564	pseudouridine synthase activity
AXA69_017200	COG0625	glutathione transferase activity
AXA69_017205	COG0625	glutathione transferase activity
AXA69_017225	COG0367	asparagine synthase
AXA69_017235	COG4651	solute:proton antiporter activity
AXA69_017235	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
AXA69_017240	COG0647	UMP catabolic process
AXA69_017250	COG1902	pentaerythritol trinitrate reductase activity
AXA69_017255	COG1253	flavin adenine dinucleotide binding
AXA69_017265	COG0277	FAD linked oxidase domain protein
AXA69_017265	COG0247	lactate metabolic process
AXA69_017275	COG2050	protein possibly involved in aromatic compounds catabolism
AXA69_017280	COG0513	Belongs to the DEAD box helicase family
AXA69_017290	COG3300	MHYT domain
AXA69_017290	COG5001	Diguanylate cyclase
AXA69_017295	COG2056	Na+-H+ antiporter family
AXA69_017300	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
AXA69_017315	COG0346	lactoylglutathione lyase activity
AXA69_017320	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
AXA69_017325	COG4660	Part of a membrane complex involved in electron transport
AXA69_017330	COG4659	FMN binding
AXA69_017335	COG4658	electron transport chain
AXA69_017345	COG2878	Part of a membrane complex involved in electron transport
AXA69_017350	COG4657	Part of a membrane complex involved in electron transport
AXA69_017355	COG0697	spore germination
AXA69_017395	COG0659	secondary active sulfate transmembrane transporter activity
AXA69_017525	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
AXA69_017530	COG1278	Cold shock
AXA69_017535	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
AXA69_017540	COG0542	response to heat
AXA69_017545	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
AXA69_017550	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
AXA69_017555	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
AXA69_017560	COG3134	Outer membrane lipoprotein
AXA69_017565	COG3706	GGDEF domain
AXA69_017570	COG0492	ferredoxin-NADP+ reductase activity
AXA69_017595	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
AXA69_017600	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
AXA69_017605	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
AXA69_017610	COG1286	toxin biosynthetic process
AXA69_017615	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
AXA69_017625	COG4172	Belongs to the ABC transporter superfamily
AXA69_017630	COG4172	Belongs to the ABC transporter superfamily
AXA69_017635	COG4171	peptide transport system, permease
AXA69_017640	COG4168	peptide transport system, permease
AXA69_017650	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
AXA69_017655	COG1842	Phage shock protein A
AXA69_017670	COG3106	COG3106 Predicted ATPase
AXA69_017675	COG3768	UPF0283 membrane protein
AXA69_017685	COG2154	pterin-4-alpha-carbinolamine dehydratase
AXA69_017700	COG2199	diguanylate cyclase activity
AXA69_017710	COG0861	Integral membrane protein TerC family
AXA69_017725	COG1022	Amp-dependent synthetase and ligase
AXA69_017730	COG0295	cytidine deaminase activity
AXA69_017735	COG1346	cytolysis
AXA69_017740	COG1380	Effector of murein hydrolase LrgA
AXA69_017755	COG2925	Exonuclease
AXA69_017770	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AXA69_017780	COG0583	DNA-binding transcription factor activity
AXA69_017785	COG2160	L-arabinose isomerase activity
AXA69_017795	COG1069	ribulokinase activity
AXA69_017800	COG1879	ABC-type sugar transport system periplasmic component
AXA69_017805	COG1129	ABC transporter
AXA69_017810	COG1172	Belongs to the binding-protein-dependent transport system permease family
AXA69_017820	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
AXA69_017825	COG1085	galactose-1-phosphate uridylyltransferase
AXA69_017830	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
AXA69_017835	COG1609	Transcriptional regulator
AXA69_017840	COG4580	involved in the transport of maltose and maltodextrins
AXA69_017880	COG2182	Extracellular solute-binding protein
AXA69_017885	COG1175	transmembrane transport
AXA69_017890	COG3833	ABC-type maltose transport systems, permease component
AXA69_017895	COG3867	Arabinogalactan endo-beta-1,4-galactanase
AXA69_017900	COG1874	Beta-galactosidase
AXA69_017910	COG0469	pyruvate kinase activity
AXA69_017915	COG0257	Belongs to the bacterial ribosomal protein bL36 family
AXA69_017920	COG0254	rRNA binding
AXA69_017935	COG1451	nucleotide metabolic process
AXA69_017950	COG3069	C4-dicarboxylate transmembrane transporter activity
AXA69_017960	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
AXA69_017960	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AXA69_017965	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AXA69_017990	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
AXA69_017995	COG1053	succinate dehydrogenase
AXA69_018005	COG0567	Dehydrogenase, E1 component
AXA69_018010	COG0508	dehydrogenase complex catalyzes the overall conversion of
AXA69_018015	COG0045	succinate-CoA ligase (ADP-forming) activity
AXA69_018020	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
AXA69_018025	COG2983	Belongs to the UPF0260 family
AXA69_018030	COG1882	Formate acetyltransferase
AXA69_018035	COG2116	formate transmembrane transporter activity
AXA69_018040	COG1944	ATP diphosphatase activity
AXA69_018045	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
AXA69_018050	COG0612	Peptidase, M16
AXA69_018065	COG2910	NAD(P)H-binding
AXA69_018070	COG0583	DNA-binding transcription factor activity
AXA69_018080	COG2207	Transcriptional regulator
AXA69_018080	COG3708	Transcriptional regulator
AXA69_018085	COG4774	siderophore transport
AXA69_018095	COG0583	DNA-binding transcription factor activity
AXA69_018100	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
AXA69_018125	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AXA69_018130	COG3046	protein related to deoxyribodipyrimidine photolyase
AXA69_018140	COG3033	Beta-eliminating lyase
AXA69_018155	COG4235	cytochrome complex assembly
AXA69_018155	COG3088	subunit of a heme lyase
AXA69_018170	COG3301	Polysulphide reductase, NrfD
AXA69_018175	COG0437	4 iron, 4 sulfur cluster binding
AXA69_018180	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
AXA69_018190	COG0247	lactate metabolic process
AXA69_018195	COG3075	Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses fumarate or nitrate as electron acceptor
AXA69_018200	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
AXA69_018205	COG3012	SEC-C Motif Domain Protein
AXA69_018210	COG0840	transmembrane signaling receptor activity
AXA69_018215	COG1846	Transcriptional regulator
AXA69_018215	COG1940	carbohydrate kinase activity
AXA69_018220	COG3290	protein histidine kinase activity
AXA69_018225	COG4565	transcriptional regulatory protein
AXA69_018245	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
AXA69_018250	COG0569	domain protein
AXA69_018250	COG2985	domain, Protein
AXA69_018260	COG0556	nucleotide-excision repair
AXA69_018270	COG0586	Pfam SNARE associated Golgi protein
AXA69_018275	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
AXA69_018280	COG3067	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
AXA69_018285	COG2186	Transcriptional regulator
AXA69_018290	COG2719	SpoVR family
AXA69_018300	COG2766	serine protein kinase
AXA69_018305	COG0514	ATP-dependent DNA helicase (RecQ)
AXA69_018310	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
AXA69_018315	COG0814	amino acid
AXA69_018355	COG0058	SHG alpha-glucan phosphorylase activity
AXA69_018360	COG0471	metal ion transport
AXA69_018365	COG3118	belongs to the thioredoxin family
AXA69_018380	COG1132	(ABC) transporter
AXA69_018390	COG2501	S4 domain
AXA69_018400	COG3243	poly(R)-hydroxyalkanoic acid synthase
AXA69_018420	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
AXA69_018425	COG2329	Antibiotic biosynthesis monooxygenase
AXA69_018465	COG1742	UPF0060 membrane protein
AXA69_018480	COG0513	Belongs to the DEAD box helicase family
AXA69_018485	COG0386	Belongs to the glutathione peroxidase family
AXA69_018495	COG1181	Belongs to the D-alanine--D-alanine ligase family
AXA69_018510	COG0730	response to heat
AXA69_018515	COG0583	DNA-binding transcription factor activity
AXA69_018530	COG3593	DNA synthesis involved in DNA repair
AXA69_018585	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
AXA69_018590	COG1011	Hydrolase
AXA69_018640	COG0205	6-phosphofructokinase activity
AXA69_018650	COG1434	Gram-negative-bacterium-type cell wall biogenesis
AXA69_018655	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
AXA69_018665	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
AXA69_018670	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
AXA69_018675	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
AXA69_018735	COG4681	YaeQ
AXA69_018755	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AXA69_018775	COG3134	Outer membrane lipoprotein
AXA69_018795	COG1028	Short-chain dehydrogenase reductase Sdr
AXA69_018800	COG0583	DNA-binding transcription factor activity
AXA69_018805	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
AXA69_018810	COG0673	inositol 2-dehydrogenase activity
AXA69_018815	COG0583	DNA-binding transcription factor activity
AXA69_018825	COG1560	Kdo2-lipid A biosynthetic process
AXA69_018830	COG1560	Kdo2-lipid A biosynthetic process
AXA69_018845	COG2199	diguanylate cyclase activity
AXA69_018845	COG2203	Gaf domain
AXA69_018855	COG0417	DNA replication proofreading
AXA69_018880	COG0534	Mate efflux family protein
AXA69_018890	COG0307	riboflavin synthase, alpha
AXA69_018900	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AXA69_018905	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
AXA69_018910	COG0697	spore germination
AXA69_018915	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
AXA69_018955	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AXA69_018960	COG3099	Belongs to the UPF0263 family
AXA69_018965	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
AXA69_018970	COG2894	cell division
AXA69_018975	COG0850	regulation of cytokinetic process
AXA69_018980	COG3100	YcgL domain-containing protein
AXA69_018985	COG2951	lytic endotransglycosylase activity
AXA69_018990	COG1760	l-serine dehydratase
AXA69_018995	COG1760	l-serine dehydratase
AXA69_019000	COG3123	guanosine phosphorylase activity
AXA69_019020	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
AXA69_019025	COG2067	long-chain fatty acid transport protein
AXA69_019030	COG2067	long-chain fatty acid transport protein
AXA69_019070	COG0714	Associated with various cellular activities
AXA69_019075	COG0183	Belongs to the thiolase family
AXA69_019080	COG1024	Enoyl-CoA hydratase
AXA69_019080	COG1250	3-hydroxyacyl-CoA dehydrogenase
AXA69_019085	COG2824	Alkylphosphonate utilization operon protein PhnA
AXA69_019105	COG1879	ABC-type sugar transport system periplasmic component
AXA69_019110	COG1129	ABC transporter
AXA69_019120	COG1172	Belongs to the binding-protein-dependent transport system permease family
AXA69_019125	COG5001	Diguanylate cyclase
AXA69_019125	COG2203	Gaf domain
AXA69_019125	COG4251	negative regulation of phosphorylation
AXA69_019125	COG3706	GGDEF domain
AXA69_019130	COG2823	Periplasmic or secreted lipoprotein
AXA69_019190	COG2378	regulation of single-species biofilm formation
AXA69_019200	COG0140	phosphoribosyl-ATP diphosphatase activity
AXA69_019200	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
AXA69_019205	COG0107	imidazoleglycerol-phosphate synthase activity
AXA69_019210	COG2205	protein histidine kinase activity
AXA69_019210	COG2198	Histidine kinase
AXA69_019210	COG0784	Response regulator, receiver
AXA69_019220	COG3437	response regulator, receiver
AXA69_019225	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
AXA69_019230	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
AXA69_019235	COG0131	Imidazoleglycerol-phosphate dehydratase
AXA69_019235	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
AXA69_019240	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
AXA69_019245	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
AXA69_019250	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
AXA69_019260	COG1199	ATP-dependent helicase activity
AXA69_019265	COG1214	PFAM Peptidase M22, glycoprotease
AXA69_019275	COG2267	carboxylic ester hydrolase activity
AXA69_019280	COG0318	PFAM AMP-dependent synthetase and ligase
AXA69_019300	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
AXA69_019305	COG2832	Protein of unknown function (DUF454)
AXA69_019310	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
AXA69_019315	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
AXA69_019320	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
AXA69_019330	COG2197	response regulator
AXA69_019335	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
AXA69_019335	COG0617	tRNA 3'-terminal CCA addition
AXA69_019335	COG0517	IMP dehydrogenase activity
AXA69_019340	COG1643	Atp-dependent helicase
AXA69_019350	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
AXA69_019355	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AXA69_019360	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
AXA69_019365	COG0709	Synthesizes selenophosphate from selenide and ATP
AXA69_019380	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
AXA69_019390	COG1254	Belongs to the acylphosphatase family
AXA69_019400	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AXA69_019400	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AXA69_019405	COG0489	protein tyrosine kinase activity
AXA69_019410	COG0572	uridine kinase
AXA69_019415	COG0717	Belongs to the dCTP deaminase family
AXA69_019420	COG0306	phosphate transporter
AXA69_019425	COG1530	ribonuclease E activity
AXA69_019435	COG0546	phosphoglycolate phosphatase activity
AXA69_019445	COG1399	metal-binding, possibly nucleic acid-binding protein
AXA69_019450	COG0333	Belongs to the bacterial ribosomal protein bL32 family
AXA69_019455	COG0416	fatty acid biosynthetic process
AXA69_019460	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AXA69_019470	COG1028	Short-chain dehydrogenase reductase Sdr
AXA69_019475	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AXA69_019480	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AXA69_019485	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
AXA69_019490	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
AXA69_019495	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
AXA69_019500	COG0470	DNA polymerase III
AXA69_019505	COG0084	hydrolase, TatD family'
AXA69_019520	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
AXA69_019520	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
AXA69_019530	COG2995	paraquat-inducible protein a
AXA69_019540	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
AXA69_019590	COG4221	oxidoreductase activity
AXA69_019665	COG4128	Pfam Zonular occludens toxin
AXA69_019670	COG4584	PFAM Integrase catalytic
AXA69_019675	COG1484	DNA-dependent DNA replication
AXA69_019745	COG4128	Pfam Zonular occludens toxin
AXA69_019760	COG1067	ATP-dependent peptidase activity
AXA69_019765	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
AXA69_019790	COG0116	Belongs to the methyltransferase superfamily
AXA69_019790	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
AXA69_019800	COG0167	dihydroorotate dehydrogenase activity
AXA69_019805	COG2902	Dehydrogenase
AXA69_019815	COG0308	aminopeptidase N
AXA69_019825	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
AXA69_019830	COG1956	GAF domain-containing protein
AXA69_019840	COG3278	Belongs to the heme-copper respiratory oxidase family
AXA69_019855	COG2010	Cytochrome c
AXA69_019865	COG2217	Heavy metal translocating P-type atpase
AXA69_019880	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AXA69_019885	COG0589	response to stress
AXA69_019890	COG0037	tRNA processing
AXA69_019905	COG0625	glutathione transferase activity
AXA69_019910	COG1869	D-ribose catabolic process
AXA69_019920	COG1172	Belongs to the binding-protein-dependent transport system permease family
AXA69_019925	COG1879	ABC-type sugar transport system periplasmic component
AXA69_019930	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AXA69_019935	COG1609	Transcriptional regulator
AXA69_019940	COG2199	diguanylate cyclase activity
AXA69_019970	COG0776	regulation of translation
AXA69_019975	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AXA69_019975	COG0072	phenylalanine-tRNA ligase activity
AXA69_019980	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
AXA69_019985	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
AXA69_019990	COG0291	Belongs to the bacterial ribosomal protein bL35 family
AXA69_019995	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
AXA69_020000	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
AXA69_020020	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
AXA69_020030	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AXA69_020035	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AXA69_020040	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AXA69_020045	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
AXA69_020050	COG3313	Fe-S protein
AXA69_020055	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AXA69_020055	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AXA69_020055	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
AXA69_020060	COG1105	Belongs to the carbohydrate kinase PfkB family
AXA69_020065	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
AXA69_020065	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
AXA69_020070	COG1609	Transcriptional regulator
AXA69_020075	COG0814	amino acid
AXA69_020085	COG5654	RES domain protein
AXA69_020090	COG0513	Belongs to the DEAD box helicase family
AXA69_020100	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
AXA69_020105	COG2890	protein-(glutamine-N5) methyltransferase activity
AXA69_020110	COG2840	Smr protein MutS2
AXA69_020115	COG3706	GGDEF domain
AXA69_020170	COG0730	response to heat
AXA69_020180	COG1028	Short-chain dehydrogenase reductase Sdr
AXA69_020190	COG1024	Enoyl-CoA hydratase
AXA69_020195	COG1024	Enoyl-CoA hydratase
AXA69_020200	COG1960	acyl-CoA dehydrogenase activity
AXA69_020210	COG1960	acyl-CoA dehydrogenase activity
AXA69_020215	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
AXA69_020220	COG1024	Enoyl-CoA hydratase
AXA69_020250	COG1584	GPR1 FUN34 yaaH family protein
AXA69_020260	COG0456	acetyltransferase
AXA69_020265	COG1115	amino acid carrier protein
AXA69_020270	COG1024	Enoyl-CoA hydratase
AXA69_020270	COG1250	3-hydroxyacyl-CoA dehydrogenase
AXA69_020285	COG3162	membrane
AXA69_020290	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AXA69_020295	COG0488	(ABC) transporter
AXA69_020300	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AXA69_020305	COG0776	regulation of translation
AXA69_020310	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
AXA69_020315	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
AXA69_020320	COG0740	serine-type endopeptidase activity
AXA69_020325	COG0544	peptidyl-prolyl cis-trans isomerase activity
AXA69_020335	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
AXA69_020340	COG4591	ABC-type transport system involved in lipoprotein release permease component
AXA69_020345	COG1136	(ABC) transporter
AXA69_020350	COG4591	ABC-type transport system involved in lipoprotein release permease component
AXA69_020360	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
AXA69_020365	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
AXA69_020370	COG4166	transmembrane transport
AXA69_020375	COG0697	spore germination
AXA69_020385	COG2062	phosphohistidine phosphatase, SixA
AXA69_020390	COG1025	Belongs to the peptidase M16 family
AXA69_020425	COG0519	Catalyzes the synthesis of GMP from XMP
AXA69_020425	COG0518	GMP synthase (glutamine-hydrolyzing) activity
AXA69_020430	COG0517	IMP dehydrogenase activity
AXA69_020430	COG0516	GMP reductase activity
AXA69_020450	COG3038	cytochrome b561
AXA69_020455	COG1570	exodeoxyribonuclease VII activity
AXA69_020470	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
AXA69_020475	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
AXA69_020480	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
AXA69_020500	COG0644	oxidoreductase
AXA69_020500	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
AXA69_020525	COG4771	TonB-dependent receptor
AXA69_020530	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AXA69_020535	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AXA69_020540	COG1120	ATPase activity
AXA69_020545	COG2977	Belongs to the P-Pant transferase superfamily
AXA69_020550	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AXA69_020555	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AXA69_020555	COG0300	oxidoreductase activity
AXA69_020555	COG0318	PFAM AMP-dependent synthetase and ligase
AXA69_020555	COG3321	synthase
AXA69_020555	COG1028	Short-chain dehydrogenase reductase Sdr
AXA69_020565	COG1028	Short-chain dehydrogenase reductase Sdr
AXA69_020570	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AXA69_020575	COG3433	isochorismatase activity
AXA69_020575	COG1535	isochorismatase
AXA69_020580	COG1021	2,3-dihydroxybenzoate-AMP ligase
AXA69_020600	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
AXA69_020605	COG3300	MHYT domain
AXA69_020605	COG5001	Diguanylate cyclase
AXA69_020620	COG0840	transmembrane signaling receptor activity
AXA69_020625	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AXA69_020630	COG3788	relative of glutathione S-transferase, MAPEG superfamily
AXA69_020635	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
AXA69_020640	COG0563	adenylate kinase activity
AXA69_020650	COG0326	Molecular chaperone. Has ATPase activity
AXA69_020655	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
AXA69_020680	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
AXA69_020700	COG3158	transport of potassium into the cell
AXA69_020705	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
AXA69_020710	COG0651	ATP synthesis coupled electron transport
AXA69_020715	COG0650	Formate hydrogenlyase subunit 4
AXA69_020720	COG3261	NADH dehydrogenase
AXA69_020720	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
AXA69_020725	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AXA69_020730	COG3260	NADH ubiquinone oxidoreductase 20
AXA69_020740	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
AXA69_020750	COG1921	L-seryl-tRNASec selenium transferase activity
AXA69_020760	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
AXA69_020765	COG0298	carbon dioxide binding
AXA69_020775	COG0309	Hydrogenase expression formation protein (HypE)
AXA69_020780	COG0375	protein maturation
AXA69_020785	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
AXA69_020800	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AXA69_020805	COG0601	transmembrane transport
AXA69_020815	COG1773	rubredoxin
AXA69_020820	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
AXA69_020825	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
AXA69_020830	COG5557	Pfam Polysulphide reductase, NrfD
AXA69_020835	COG0437	4 iron, 4 sulfur cluster binding
AXA69_020840	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
AXA69_020845	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
AXA69_020870	COG1435	thymidine kinase activity
AXA69_020875	COG1757	Na H antiporter
AXA69_020885	COG2916	Histone family protein nucleoid-structuring protein H-NS
AXA69_020890	COG2096	Adenosyltransferase
AXA69_020895	COG3530	Putative quorum-sensing-regulated virulence factor
AXA69_020900	COG0602	queuosine metabolic process
AXA69_020905	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
AXA69_020920	COG0284	orotidine-5'-phosphate decarboxylase activity
AXA69_020925	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
AXA69_020935	COG0776	regulation of translation
AXA69_020940	COG0539	negative regulation of cytoplasmic translation
AXA69_020945	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
AXA69_020950	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
AXA69_020960	COG0583	DNA-binding transcription factor activity
AXA69_020965	COG2814	Major facilitator Superfamily
AXA69_021000	COG0583	DNA-binding transcription factor activity
AXA69_021005	COG3437	response regulator, receiver
AXA69_021030	COG4989	oxidoreductase activity
AXA69_021035	COG0724	RNA recognition motif
AXA69_021045	COG1126	abc transporter atp-binding protein
AXA69_021050	COG0765	amino acid transport
AXA69_021055	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AXA69_021060	COG4597	amino acid ABC transporter
AXA69_021075	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
AXA69_021090	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
AXA69_021095	COG1360	Flagellar Motor Protein
AXA69_021100	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AXA69_021105	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AXA69_021110	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AXA69_021110	COG0649	NAD binding
AXA69_021125	COG1034	ATP synthesis coupled electron transport
AXA69_021130	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
AXA69_021135	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AXA69_021140	COG0839	Belongs to the complex I subunit 6 family
AXA69_021145	COG0713	ATP synthesis coupled electron transport
AXA69_021155	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AXA69_021160	COG1007	ATP synthesis coupled electron transport
AXA69_021180	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AXA69_021185	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AXA69_021220	COG0537	adenosine 5'-monophosphoramidase activity
AXA69_021235	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
AXA69_021250	COG1301	dicarboxylic acid transport
AXA69_021260	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
AXA69_021265	COG0861	Integral membrane protein TerC family
AXA69_021280	COG0444	Belongs to the ABC transporter superfamily
AXA69_021285	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AXA69_021290	COG0601	transmembrane transport
AXA69_021300	COG2095	MarC family integral membrane protein
AXA69_021310	COG1454	alcohol dehydrogenase
AXA69_021310	COG1012	belongs to the aldehyde dehydrogenase family
AXA69_021320	COG3275	phosphorelay sensor kinase activity
AXA69_021325	COG3279	Response regulator of the LytR AlgR family
AXA69_021330	COG1966	Carbon starvation protein
AXA69_021340	COG1566	PFAM secretion protein HlyD family protein
AXA69_021345	COG1061	Type III restriction enzyme res subunit
AXA69_021350	COG2027	D-alanyl-D-alanine carboxypeptidase
AXA69_021355	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
AXA69_021365	COG0436	Aminotransferase
AXA69_021370	COG1288	antiporter activity
AXA69_021375	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
AXA69_021445	COG1242	4 iron, 4 sulfur cluster binding
AXA69_021450	COG0067	glutamate synthase
AXA69_021450	COG0069	glutamate synthase activity
AXA69_021450	COG0070	glutamate synthase
AXA69_021455	COG0493	'glutamate synthase
AXA69_021470	COG0789	Transcriptional regulator
AXA69_021495	COG0513	Belongs to the DEAD box helicase family
AXA69_021500	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AXA69_021540	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AXA69_021545	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
AXA69_021550	COG0505	Belongs to the CarA family
AXA69_021555	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
AXA69_021570	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
AXA69_021575	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
AXA69_021580	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AXA69_021585	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
AXA69_021590	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
AXA69_021595	COG4138	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system
AXA69_021605	COG2205	protein histidine kinase activity
AXA69_021605	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AXA69_021650	COG2119	membrane
AXA69_021710	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
AXA69_021720	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AXA69_021750	COG4974	Belongs to the 'phage' integrase family
AXA69_021760	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
AXA69_021825	COG4695	Portal protein
AXA69_021965	COG4737	Cytotoxic translational repressor of toxin-antitoxin stability system
AXA69_022035	COG4792	protein secretion
AXA69_022040	COG4791	protein targeting
AXA69_022045	COG4794	Type iii secretion
AXA69_022050	COG4790	Type iii secretion
AXA69_022120	COG0457	Tetratricopeptide repeat
AXA69_022210	COG1317	bacterial-type flagellum organization
AXA69_022240	COG3328	transposase activity
AXA69_022365	COG1192	Involved in chromosome partitioning
AXA69_022380	COG2916	Histone family protein nucleoid-structuring protein H-NS
AXA69_022405	COG4584	PFAM Integrase catalytic
AXA69_022410	COG1484	DNA-dependent DNA replication
AXA69_022435	COG0393	Putative heavy-metal-binding
AXA69_022465	COG3328	transposase activity
AXA69_022475	COG1192	Involved in chromosome partitioning
AXA69_022485	COG2916	Histone family protein nucleoid-structuring protein H-NS
AXA69_022515	COG1192	Involved in chromosome partitioning
AXA69_022520	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
AXA69_022530	COG2194	sulfuric ester hydrolase activity
AXA69_022535	COG2194	sulfuric ester hydrolase activity
AXA69_022560	COG1484	DNA-dependent DNA replication
AXA69_022565	COG4584	PFAM Integrase catalytic
AXA69_022605	COG2003	Belongs to the UPF0758 family
AXA69_022670	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
AXA69_022865	COG4584	PFAM Integrase catalytic
AXA69_022870	COG1484	DNA-dependent DNA replication
AXA69_022875	COG3328	transposase activity
AXA69_022905	COG4792	protein secretion
AXA69_022910	COG4791	protein targeting
AXA69_022915	COG4794	Type iii secretion
AXA69_022920	COG4790	Type iii secretion
AXA69_023005	COG3077	Addiction module antitoxin, RelB DinJ family
AXA69_023010	COG2026	Addiction module toxin, RelE StbE family
AXA69_023060	COG3328	transposase activity