locus-tag	class	description
PI861_00080	COG4737	Cytotoxic translational repressor of toxin-antitoxin stability system
PI861_00105	COG0322	excinuclease ABC activity
PI861_00110	COG2197	response regulator
PI861_00115	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
PI861_00120	COG2835	tetraacyldisaccharide 4'-kinase activity
PI861_00125	COG1663	tetraacyldisaccharide 4'-kinase activity
PI861_00130	COG1132	(ABC) transporter
PI861_00135	COG0658	competence protein
PI861_00135	COG2333	competence protein COMEC
PI861_00150	COG0433	COG0433 Predicted ATPase
PI861_00155	COG1448	Aminotransferase
PI861_00170	COG1199	ATP-dependent helicase activity
PI861_00180	COG0123	including yeast histone deacetylase and acetoin utilization protein
PI861_00185	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
PI861_00190	COG1785	Belongs to the alkaline phosphatase family
PI861_00210	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
PI861_00225	COG2271	Major facilitator Superfamily
PI861_00230	COG3706	GGDEF domain
PI861_00235	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
PI861_00240	COG0765	amino acid transport
PI861_00245	COG1126	abc transporter atp-binding protein
PI861_00255	COG0531	amino acid
PI861_00270	COG1253	flavin adenine dinucleotide binding
PI861_00275	COG0704	Plays a role in the regulation of phosphate uptake
PI861_00280	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
PI861_00285	COG0581	inorganic phosphate transmembrane transporter activity
PI861_00290	COG0573	inorganic phosphate transmembrane transporter activity
PI861_00295	COG0590	tRNA wobble adenosine to inosine editing
PI861_00310	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
PI861_00330	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
PI861_00335	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
PI861_00340	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
PI861_00345	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
PI861_00375	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
PI861_00380	COG0248	Ppx GppA phosphatase
PI861_00385	COG2239	Acts as a magnesium transporter
PI861_00405	COG1706	bacterial-type flagellum-dependent cell motility
PI861_00410	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
PI861_00420	COG4787	bacterial-type flagellum-dependent cell motility
PI861_00440	COG1815	bacterial-type flagellum-dependent cell motility
PI861_00450	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
PI861_00455	COG0835	chemotaxis
PI861_00455	COG0784	Response regulator, receiver
PI861_00475	COG0622	Phosphoesterase
PI861_00480	COG4166	transmembrane transport
PI861_00535	COG1278	Cold shock
PI861_00575	COG1484	DNA-dependent DNA replication
PI861_00580	COG4584	PFAM Integrase catalytic
PI861_00595	COG3132	Protein of unknown function, DUF480
PI861_00605	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
PI861_00620	COG0438	transferase activity, transferring glycosyl groups
PI861_00655	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
PI861_00670	COG0490	domain, Protein
PI861_00670	COG0471	metal ion transport
PI861_00675	COG0471	metal ion transport
PI861_00675	COG3273	potassium ion transport
PI861_00695	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
PI861_00700	COG0438	transferase activity, transferring glycosyl groups
PI861_00720	COG1450	Type ii and iii secretion system protein
PI861_00765	COG1459	type II secretion system
PI861_00770	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
PI861_00790	COG1091	dTDP-4-dehydrorhamnose reductase activity
PI861_00810	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
PI861_00815	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
PI861_00820	COG1309	transcriptional regulator
PI861_00840	COG1946	Acyl-CoA thioesterase
PI861_00850	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
PI861_00860	COG0009	L-threonylcarbamoyladenylate synthase
PI861_00870	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
PI861_00875	COG0512	Glutamine amidotransferase of anthranilate synthase
PI861_00875	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
PI861_00880	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
PI861_00885	COG0135	phosphoribosylanthranilate isomerase activity
PI861_00885	COG0134	indole-3-glycerol-phosphate synthase activity
PI861_00890	COG0133	tryptophan synthase activity
PI861_00895	COG0159	tryptophan synthase activity
PI861_00920	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
PI861_00920	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
PI861_00920	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
PI861_00930	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
PI861_00950	COG0482	sulfurtransferase activity
PI861_00955	COG2915	High frequency lysogenization protein hflD homolog
PI861_00960	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
PI861_00965	COG2850	peptidyl-arginine hydroxylation
PI861_00985	COG3153	acetyltransferase
PI861_01005	COG0259	pyridoxamine-phosphate oxidase activity
PI861_01020	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
PI861_01020	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
PI861_01025	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
PI861_01045	COG3088	subunit of a heme lyase
PI861_01045	COG4235	cytochrome complex assembly
PI861_01050	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
PI861_01055	COG1138	Cytochrome C-type biogenesis protein
PI861_01060	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
PI861_01065	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
PI861_01070	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
PI861_01075	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
PI861_01095	COG0835	chemotaxis
PI861_01105	COG1192	Involved in chromosome partitioning
PI861_01110	COG1360	Flagellar Motor Protein
PI861_01115	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
PI861_01120	COG2201	protein-glutamate methylesterase activity
PI861_01125	COG0643	Histidine kinase
PI861_01125	COG0784	Response regulator, receiver
PI861_01125	COG2198	Histidine kinase
PI861_01130	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
PI861_01155	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
PI861_01165	COG1684	flagellar biosynthetic protein fliR
PI861_01220	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
PI861_01230	COG1677	Flagellar hook-basal body complex protein FliE
PI861_01240	COG1574	metal-dependent hydrolase with the TIM-barrel fold
PI861_01255	COG1342	Belongs to the UPF0251 family
PI861_01275	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
PI861_01300	COG1737	Transcriptional regulator
PI861_01305	COG0469	pyruvate kinase activity
PI861_01315	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
PI861_01320	COG1960	acyl-CoA dehydrogenase activity
PI861_01330	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
PI861_01365	COG3209	COG3209 Rhs family protein
PI861_01375	COG1484	DNA-dependent DNA replication
PI861_01380	COG4584	PFAM Integrase catalytic
PI861_01410	COG1376	ErfK ybiS ycfS ynhG family protein
PI861_01410	COG1388	LysM domain
PI861_01425	COG3129	Specifically methylates the adenine in position 1618 of 23S rRNA
PI861_01430	COG0791	NLP P60 protein
PI861_01435	COG2091	lysine biosynthetic process via aminoadipic acid
PI861_01440	COG3118	belongs to the thioredoxin family
PI861_01450	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
PI861_01455	COG0788	formyltetrahydrofolate deformylase activity
PI861_01465	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
PI861_01485	COG0366	Alpha amylase catalytic
PI861_01490	COG0739	heme binding
PI861_01490	COG1196	nuclear chromosome segregation
PI861_01490	COG0741	lytic transglycosylase activity
PI861_01495	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
PI861_01500	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
PI861_01505	COG0673	inositol 2-dehydrogenase activity
PI861_01535	COG1032	radical SAM domain protein
PI861_01545	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
PI861_01550	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
PI861_01555	COG3706	GGDEF domain
PI861_01560	COG1752	Esterase of the alpha-beta hydrolase superfamily
PI861_01565	COG0733	neurotransmitter:sodium symporter activity
PI861_01595	COG0281	malic enzyme
PI861_01600	COG2207	Transcriptional regulator
PI861_01605	COG0534	Mate efflux family protein
PI861_01620	COG2233	PERMEase
PI861_01625	COG0095	Lipoate-protein ligase
PI861_01630	COG1115	amino acid carrier protein
PI861_01635	COG0019	diaminopimelate decarboxylase activity
PI861_01675	COG1131	(ABC) transporter
PI861_01680	COG0545	Peptidyl-prolyl cis-trans isomerase
PI861_01685	COG3142	Participates in the control of copper homeostasis
PI861_01690	COG1940	carbohydrate kinase activity
PI861_01710	COG5002	protein histidine kinase activity
PI861_01715	COG0745	RESPONSE REGULATOR receiver
PI861_01720	COG0346	lactoylglutathione lyase activity
PI861_01725	COG3706	GGDEF domain
PI861_01755	COG3290	protein histidine kinase activity
PI861_01760	COG0281	malic enzyme
PI861_01775	COG1846	Transcriptional regulator
PI861_01780	COG1566	PFAM secretion protein HlyD family protein
PI861_01805	COG0602	queuosine metabolic process
PI861_01815	COG1328	CTP reductase activity
PI861_01825	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
PI861_01830	COG3115	cell septum assembly
PI861_01835	COG1196	nuclear chromosome segregation
PI861_01845	COG2860	membrane
PI861_01855	COG3108	Peptidase M15
PI861_01860	COG2989	Protein conserved in bacteria
PI861_01875	COG0463	Glycosyl transferase, family 2
PI861_01890	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
PI861_01895	COG0739	heme binding
PI861_01900	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
PI861_01915	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
PI861_01925	COG3091	SprT-like family
PI861_01935	COG1385	rRNA (uridine-N3-)-methyltransferase activity
PI861_01940	COG0189	ligase activity
PI861_01955	COG1678	Uncharacterized ACR, COG1678
PI861_01960	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
PI861_01980	COG0714	Associated with various cellular activities
PI861_01995	COG1115	amino acid carrier protein
PI861_02000	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
PI861_02015	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
PI861_02035	COG1301	dicarboxylic acid transport
PI861_02060	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
PI861_02065	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
PI861_02070	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
PI861_02075	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
PI861_02085	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
PI861_02090	COG0737	Belongs to the 5'-nucleotidase family
PI861_02095	COG0193	aminoacyl-tRNA hydrolase activity
PI861_02100	COG0012	GTP binding
PI861_02165	COG0471	metal ion transport
PI861_02165	COG0490	domain, Protein
PI861_02175	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
PI861_02205	COG0443	Heat shock 70 kDa protein
PI861_02215	COG0366	Alpha amylase catalytic
PI861_02225	COG0488	(ABC) transporter
PI861_02235	COG1013	pyruvate-flavodoxin oxidoreductase activity
PI861_02235	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
PI861_02235	COG0674	pyruvate-flavodoxin oxidoreductase activity
PI861_02235	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
PI861_02245	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
PI861_02255	COG1012	belongs to the aldehyde dehydrogenase family
PI861_02265	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
PI861_02280	COG0180	Tryptophanyl-tRNA synthetase
PI861_02285	COG0546	phosphoglycolate phosphatase activity
PI861_02290	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
PI861_02295	COG0338	D12 class N6 adenine-specific DNA methyltransferase
PI861_02305	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
PI861_02310	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
PI861_02340	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
PI861_02345	COG0583	DNA-binding transcription factor activity
PI861_02365	COG0583	DNA-binding transcription factor activity
PI861_02380	COG0739	heme binding
PI861_02395	COG1511	domain protein
PI861_02395	COG3264	Mechanosensitive ion channel
PI861_02400	COG0584	glycerophosphoryl diester phosphodiesterase
PI861_02410	COG1053	succinate dehydrogenase
PI861_02415	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
PI861_02420	COG3029	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
PI861_02425	COG3080	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
PI861_02445	COG3214	Protein conserved in bacteria
PI861_02485	COG0642	Histidine kinase
PI861_02495	COG0516	GMP reductase activity
PI861_02505	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
PI861_02515	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
PI861_02535	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
PI861_02550	COG3706	GGDEF domain
PI861_02560	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
PI861_02565	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
PI861_02570	COG1702	phosphate starvation-inducible protein PhoH
PI861_02575	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
PI861_02580	COG4535	Mg2 and Co2 transporter CorC
PI861_02585	COG0815	Transfers the fatty acyl group on membrane lipoproteins
PI861_02590	COG2888	peptidyl-tyrosine sulfation
PI861_02595	COG0495	leucyl-tRNA aminoacylation
PI861_02615	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
PI861_02620	COG0799	negative regulation of ribosome biogenesis
PI861_02625	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
PI861_02630	COG0768	penicillin binding
PI861_02635	COG0772	Belongs to the SEDS family
PI861_02645	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
PI861_02650	COG1686	Belongs to the peptidase S11 family
PI861_02655	COG2921	Belongs to the UPF0250 family
PI861_02660	COG0321	lipoyl(octanoyl) transferase activity
PI861_02665	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
PI861_02680	COG3621	Patatin-like phospholipase
PI861_02710	COG1484	DNA-dependent DNA replication
PI861_02715	COG4584	PFAM Integrase catalytic
PI861_02750	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
PI861_02755	COG3545	Serine hydrolase
PI861_02770	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
PI861_02780	COG1970	mechanosensitive ion channel activity
PI861_02790	COG4974	Belongs to the 'phage' integrase family
PI861_02805	COG0312	modulator of DNA gyrase
PI861_02860	COG1422	Protein of unknown function (DUF1090)
PI861_02865	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
PI861_02870	COG3706	GGDEF domain
PI861_02880	COG1185	polyribonucleotide nucleotidyltransferase activity
PI861_02885	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
PI861_02890	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
PI861_02895	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
PI861_02900	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
PI861_02905	COG0195	Participates in both transcription termination and antitermination
PI861_02910	COG0779	Required for maturation of 30S ribosomal subunits
PI861_02925	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
PI861_02930	COG0149	triose-phosphate isomerase activity
PI861_02935	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
PI861_02940	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
PI861_02950	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
PI861_02955	COG1534	Rna-binding protein
PI861_02990	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
PI861_02995	COG1722	exodeoxyribonuclease VII activity
PI861_03000	COG0142	geranyltranstransferase activity
PI861_03005	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
PI861_03015	COG0601	transmembrane transport
PI861_03025	COG4172	Belongs to the ABC transporter superfamily
PI861_03030	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
PI861_03035	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
PI861_03040	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
PI861_03045	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
PI861_03060	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
PI861_03060	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
PI861_03065	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
PI861_03080	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
PI861_03095	COG3381	protein complex oligomerization
PI861_03125	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
PI861_03130	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
PI861_03135	COG0511	ligase activity, forming carbon-carbon bonds
PI861_03140	COG0439	Biotin carboxylase
PI861_03145	COG3924	membrane
PI861_03150	COG4145	pantothenate transmembrane transporter activity
PI861_03155	COG1263	PTS System
PI861_03155	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
PI861_03155	COG2190	(PTS) system
PI861_03160	COG0583	DNA-binding transcription factor activity
PI861_03165	COG0604	alcohol dehydrogenase
PI861_03170	COG2264	protein methyltransferase activity
PI861_03180	COG4303	Ethanolamine ammonia lyase large subunit
PI861_03185	COG4302	ethanolamine ammonia-lyase activity
PI861_03210	COG0778	Nitroreductase
PI861_03215	COG0446	pyridine nucleotide-disulphide oxidoreductase
PI861_03215	COG1902	pentaerythritol trinitrate reductase activity
PI861_03220	COG0616	signal peptide processing
PI861_03240	COG3139	Protein of unknown function (DUF1315)
PI861_03245	COG0252	asparaginase activity
PI861_03250	COG0786	glutamate:sodium symporter activity
PI861_03265	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
PI861_03270	COG0384	phenazine biosynthesis protein PhzF
PI861_03285	COG0175	sulfate reduction
PI861_03290	COG2113	Glycine betaine
PI861_03295	COG4176	ABC-type proline glycine betaine transport system permease component
PI861_03300	COG4175	Glycine betaine
PI861_03310	COG3610	response to peptide
PI861_03320	COG2966	Psort location CytoplasmicMembrane, score
PI861_03330	COG0521	Mo-molybdopterin cofactor biosynthetic process
PI861_03340	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
PI861_03345	COG1028	Short-chain dehydrogenase reductase Sdr
PI861_03355	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
PI861_03380	COG2986	histidine ammonia-lyase
PI861_03395	COG0318	PFAM AMP-dependent synthetase and ligase
PI861_03405	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
PI861_03410	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
PI861_03445	COG1858	cytochrome C peroxidase
PI861_03455	COG2313	pseudouridylate synthase activity
PI861_03460	COG1522	sequence-specific DNA binding
PI861_03460	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
PI861_03490	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
PI861_03495	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
PI861_03505	COG1073	alpha beta
PI861_03510	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
PI861_03520	COG2195	Cleaves the N-terminal amino acid of tripeptides
PI861_03525	COG4608	Belongs to the ABC transporter superfamily
PI861_03530	COG0444	Belongs to the ABC transporter superfamily
PI861_03535	COG0747	negative chemotaxis
PI861_03540	COG4239	(ABC) transporter, permease
PI861_03545	COG4174	ABC transporter (Permease)
PI861_03550	COG0601	transmembrane transport
PI861_03555	COG4206	TonB-dependent receptor
PI861_03565	COG0811	peptide transport
PI861_03570	COG0811	peptide transport
PI861_03575	COG0848	biopolymer transport protein
PI861_03620	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
PI861_03625	COG0840	transmembrane signaling receptor activity
PI861_03635	COG1278	Cold shock
PI861_03665	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
PI861_03675	COG0688	phosphatidylethanolamine metabolic process
PI861_03680	COG4628	conserved protein (DUF2132)
PI861_03700	COG3300	MHYT domain
PI861_03700	COG5001	Diguanylate cyclase
PI861_03705	COG3076	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome
PI861_03740	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
PI861_03745	COG1012	belongs to the aldehyde dehydrogenase family
PI861_03755	COG1132	(ABC) transporter
PI861_03765	COG2897	thiosulfate sulfurtransferase activity
PI861_03770	COG2066	Belongs to the glutaminase family
PI861_03775	COG3171	Protein conserved in bacteria
PI861_03780	COG0220	tRNA (guanine-N7-)-methyltransferase activity
PI861_03795	COG2200	EAL domain
PI861_03800	COG1090	epimerase
PI861_03805	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
PI861_03810	COG4181	ATPase activity
PI861_03815	COG2755	lipolytic protein G-D-S-L family
PI861_03820	COG0835	chemotaxis
PI861_03820	COG0784	Response regulator, receiver
PI861_03830	COG0569	domain protein
PI861_03830	COG2985	domain, Protein
PI861_03835	COG1272	protein, Hemolysin III
PI861_03840	COG0076	glutamate decarboxylase activity
PI861_03845	COG2917	probably involved in intracellular septation
PI861_03850	COG2350	Protein conserved in bacteria
PI861_03860	COG1555	photosystem II stabilization
PI861_03865	COG1210	Utp--glucose-1-phosphate uridylyltransferase
PI861_03870	COG3104	oligopeptide transport
PI861_03875	COG0745	RESPONSE REGULATOR receiver
PI861_03905	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
PI861_03920	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
PI861_03925	COG1280	lysine exporter protein (LysE YggA)
PI861_03955	COG0316	Belongs to the HesB IscA family
PI861_03965	COG0038	chloride channel
PI861_03970	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
PI861_03985	COG0671	phosphoesterase, PA-phosphatase related
PI861_03995	COG3437	response regulator, receiver
PI861_03995	COG0784	Response regulator, receiver
PI861_04000	COG0583	DNA-binding transcription factor activity
PI861_04005	COG2076	Multidrug Resistance protein
PI861_04015	COG0346	lactoylglutathione lyase activity
PI861_04020	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
PI861_04025	COG1643	Atp-dependent helicase
PI861_04035	COG1489	DNA binding
PI861_04040	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
PI861_04045	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
PI861_04050	COG0617	tRNA 3'-terminal CCA addition
PI861_04055	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
PI861_04060	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
PI861_04065	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
PI861_04075	COG0842	Transport permease protein
PI861_04080	COG1131	(ABC) transporter
PI861_04095	COG0163	prenyltransferase activity
PI861_04100	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
PI861_04105	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
PI861_04110	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
PI861_04120	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
PI861_04120	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
PI861_04120	COG0506	proline dehydrogenase activity
PI861_04125	COG4991	sh3 domain protein
PI861_04130	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
PI861_04150	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
PI861_04155	COG1640	4-alpha-glucanotransferase
PI861_04160	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
PI861_04165	COG0676	glucose-6-phosphate 1-epimerase activity
PI861_04170	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
PI861_04240	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
PI861_04245	COG2885	chlorophyll binding
PI861_04250	COG0823	Involved in the tonB-independent uptake of proteins
PI861_04265	COG0811	peptide transport
PI861_04270	COG0824	Thioesterase
PI861_04275	COG3790	cyd operon protein YbgE
PI861_04280	COG4890	Cyd operon protein YbgT
PI861_04285	COG1294	oxidase, subunit
PI861_04290	COG1271	oxidase subunit
PI861_04295	COG2255	four-way junction helicase activity
PI861_04300	COG0632	four-way junction helicase activity
PI861_04305	COG0840	transmembrane signaling receptor activity
PI861_04310	COG0442	prolyl-tRNA aminoacylation
PI861_04320	COG1902	pentaerythritol trinitrate reductase activity
PI861_04330	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
PI861_04360	COG0714	Associated with various cellular activities
PI861_04370	COG0456	acetyltransferase
PI861_04380	COG1022	Amp-dependent synthetase and ligase
PI861_04390	COG2918	glutathione biosynthetic process
PI861_04395	COG0612	Peptidase, M16
PI861_04400	COG1238	metal cluster binding
PI861_04405	COG1064	alcohol dehydrogenase
PI861_04435	COG0359	binds to the 23S rRNA
PI861_04440	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
PI861_04445	COG0360	Binds together with S18 to 16S ribosomal RNA
PI861_04450	COG1914	H( )-stimulated, divalent metal cation uptake system
PI861_04470	COG2153	protein acetylation
PI861_04480	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
PI861_04485	COG0557	exoribonuclease II activity
PI861_04490	COG3706	GGDEF domain
PI861_04495	COG1854	S-ribosylhomocysteine lyase activity
PI861_04510	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
PI861_04510	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
PI861_04550	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
PI861_04555	COG1047	Peptidyl-prolyl cis-trans
PI861_04560	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
PI861_04565	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
PI861_04570	COG0196	riboflavin kinase activity
PI861_04575	COG0728	peptidoglycan biosynthetic process
PI861_04580	COG0268	Binds directly to 16S ribosomal RNA
PI861_04585	COG0640	Transcriptional regulator
PI861_04590	COG0583	DNA-binding transcription factor activity
PI861_04600	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
PI861_04605	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
PI861_04610	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
PI861_04620	COG1051	belongs to the nudix hydrolase family
PI861_04625	COG3066	DNA modification
PI861_04635	COG0335	large ribosomal subunit rRNA binding
PI861_04640	COG0336	Belongs to the RNA methyltransferase TrmD family
PI861_04645	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
PI861_04650	COG0228	four-way junction DNA binding
PI861_04655	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
PI861_04660	COG4137	Cytochrome C assembly protein
PI861_04665	COG4536	flavin adenine dinucleotide binding
PI861_04670	COG1959	2 iron, 2 sulfur cluster binding
PI861_04675	COG1017	nitric oxide dioxygenase activity
PI861_04675	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
PI861_04680	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
PI861_04685	COG0039	L-malate dehydrogenase activity
PI861_04690	COG4160	amino acid transport
PI861_04700	COG4215	(ABC) transporter
PI861_04705	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
PI861_04710	COG1126	abc transporter atp-binding protein
PI861_04715	COG1438	arginine binding
PI861_04720	COG2837	iron assimilation
PI861_04725	COG3842	ATPase activity
PI861_04735	COG1840	ABC-type Fe3 transport system, periplasmic component
PI861_04740	COG0347	Belongs to the P(II) protein family
PI861_04755	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
PI861_04775	COG1929	Belongs to the glycerate kinase type-1 family
PI861_04780	COG2610	gluconate transmembrane transporter activity
PI861_04780	COG2610	gluconate transmembrane transporter activity
PI861_04785	COG3835	regulator
PI861_04790	COG3112	Uncharacterised protein family (UPF0231)
PI861_04805	COG0840	transmembrane signaling receptor activity
PI861_04810	COG3568	Endonuclease Exonuclease Phosphatase
PI861_04825	COG0513	Belongs to the DEAD box helicase family
PI861_04865	COG1448	Aminotransferase
PI861_04885	COG1328	CTP reductase activity
PI861_04920	COG1215	transferase activity, transferring glycosyl groups
PI861_04925	COG0726	polysaccharide deacetylase
PI861_04925	COG1649	PFAM Uncharacterised BCR, COG1649
PI861_04930	COG0726	polysaccharide deacetylase
PI861_04930	COG1649	PFAM Uncharacterised BCR, COG1649
PI861_04970	COG0840	transmembrane signaling receptor activity
PI861_04975	COG3397	chitin binding
PI861_04980	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
PI861_04985	COG1126	abc transporter atp-binding protein
PI861_04995	COG0765	amino acid transport
PI861_05000	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
PI861_05005	COG0583	DNA-binding transcription factor activity
PI861_05010	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
PI861_05015	COG4208	sulfate ABC transporter
PI861_05020	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
PI861_05030	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
PI861_05035	COG3174	membrane
PI861_05040	COG0110	maltose O-acetyltransferase activity
PI861_05070	COG1942	4-Oxalocrotonate Tautomerase
PI861_05080	COG0583	DNA-binding transcription factor activity
PI861_05085	COG0165	Argininosuccinate lyase
PI861_05090	COG0137	argininosuccinate synthase activity
PI861_05100	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
PI861_05105	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
PI861_05115	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
PI861_05125	COG2072	flavoprotein involved in K transport
PI861_05130	COG1393	Belongs to the ArsC family
PI861_05135	COG0798	PFAM Bile acid sodium symporter
PI861_05155	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
PI861_05175	COG3068	Protein conserved in bacteria
PI861_05185	COG0739	heme binding
PI861_05205	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
PI861_05210	COG1121	(ABC) transporter
PI861_05215	COG1108	ABC-type Mn2 Zn2 transport systems permease components
PI861_05220	COG0583	DNA-binding transcription factor activity
PI861_05230	COG1573	uracil-dna glycosylase
PI861_05235	COG2962	Rard protein
PI861_05245	COG2827	Endonuclease containing a URI domain
PI861_05260	COG1842	Phage shock protein A
PI861_05265	COG0204	Acyl-transferase
PI861_05285	COG3118	belongs to the thioredoxin family
PI861_05290	COG2259	Doxx family
PI861_05345	COG1051	belongs to the nudix hydrolase family
PI861_05350	COG3150	esterase
PI861_05360	COG3151	Protein conserved in bacteria
PI861_05365	COG0494	nUDIX hydrolase
PI861_05375	COG1538	Outer membrane efflux protein
PI861_05380	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
PI861_05380	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
PI861_05385	COG1560	Kdo2-lipid A biosynthetic process
PI861_05400	COG1392	Phosphate transport regulator
PI861_05405	COG0306	phosphate transporter
PI861_05410	COG0617	tRNA 3'-terminal CCA addition
PI861_05415	COG3267	Type II secretory pathway component ExeA
PI861_05415	COG3409	Peptidoglycan-binding domain 1 protein
PI861_05425	COG1194	a g-specific adenine glycosylase
PI861_05430	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
PI861_05440	COG3111	PFAM Bacterial OB fold (BOF) protein
PI861_05445	COG3240	lipase activity
PI861_05460	COG3009	Protein conserved in bacteria
PI861_05465	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
PI861_05465	COG3008	intermembrane lipid transfer
PI861_05470	COG2995	paraquat-inducible protein a
PI861_05480	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
PI861_05495	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
PI861_05500	COG2813	Specifically methylates the guanine in position
PI861_05505	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
PI861_05510	COG0297	glycogen (starch) synthase activity
PI861_05550	COG1757	Na H antiporter
PI861_05560	COG0110	maltose O-acetyltransferase activity
PI861_05565	COG0366	Alpha amylase catalytic
PI861_05585	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
PI861_05590	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
PI861_05595	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
PI861_05600	COG2723	6-phospho-beta-galactosidase activity
PI861_05605	COG1447	Phosphotransferase system cellobiose-specific component IIA
PI861_05610	COG1940	carbohydrate kinase activity
PI861_05620	COG1609	Transcriptional regulator
PI861_05630	COG0252	asparaginase activity
PI861_05645	COG1803	Methylglyoxal synthase
PI861_05670	COG1444	tRNA N-acetyltransferase activity
PI861_05675	COG1028	Short-chain dehydrogenase reductase Sdr
PI861_05680	COG0784	Response regulator, receiver
PI861_05680	COG0835	chemotaxis
PI861_05690	COG3314	Sporulation integral membrane protein YlbJ
PI861_05790	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
PI861_05795	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
PI861_05810	COG0477	Major facilitator Superfamily
PI861_05815	COG0523	cobalamin synthesis protein
PI861_05825	COG1280	lysine exporter protein (LysE YggA)
PI861_05835	COG0583	DNA-binding transcription factor activity
PI861_05840	COG1028	Short-chain dehydrogenase reductase Sdr
PI861_05845	COG2200	EAL domain
PI861_05850	COG1049	propionate catabolic process, 2-methylcitrate cycle
PI861_05865	COG0840	transmembrane signaling receptor activity
PI861_05875	COG3447	MASE1 domain protein
PI861_05875	COG5002	protein histidine kinase activity
PI861_05875	COG5001	Diguanylate cyclase
PI861_05880	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
PI861_05885	COG0508	dehydrogenase complex catalyzes the overall conversion of
PI861_05890	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
PI861_05895	COG2186	Transcriptional regulator
PI861_05920	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
PI861_05930	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
PI861_05940	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
PI861_05945	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
PI861_05950	COG0494	nUDIX hydrolase
PI861_05960	COG0653	protein targeting
PI861_05970	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
PI861_05975	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
PI861_05980	COG0849	cell division
PI861_05985	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
PI861_05990	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
PI861_05995	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
PI861_06000	COG0772	Belongs to the SEDS family
PI861_06005	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
PI861_06010	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
PI861_06015	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
PI861_06025	COG0768	penicillin binding
PI861_06030	COG3116	cell division
PI861_06035	COG0275	rRNA processing
PI861_06040	COG2001	Belongs to the MraZ family
PI861_06050	COG0741	lytic transglycosylase activity
PI861_06050	COG1388	LysM domain
PI861_06055	COG1360	Flagellar Motor Protein
PI861_06060	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
PI861_06090	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
PI861_06105	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
PI861_06135	COG1706	bacterial-type flagellum-dependent cell motility
PI861_06140	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
PI861_06145	COG4786	Flagellar basal body rod
PI861_06150	COG4786	Flagellar basal body rod
PI861_06155	COG1749	Flagellar hook protein flgE
PI861_06175	COG1815	bacterial-type flagellum-dependent cell motility
PI861_06185	COG2747	anti-sigma28 factor FlgM
PI861_06210	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
PI861_06220	COG1677	Flagellar hook-basal body complex protein FliE
PI861_06245	COG1987	bacterial-type flagellum assembly
PI861_06270	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
PI861_06275	COG3107	peptidoglycan biosynthetic process
PI861_06280	COG0792	nuclease activity
PI861_06285	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
PI861_06290	COG2823	Periplasmic or secreted lipoprotein
PI861_06295	COG2969	positive regulation of protein catabolic process
PI861_06300	COG0625	glutathione transferase activity
PI861_06305	COG2857	Cytochrome c1
PI861_06310	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
PI861_06315	COG0723	plastoquinol--plastocyanin reductase activity
PI861_06320	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
PI861_06325	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
PI861_06330	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
PI861_06340	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
PI861_06345	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
PI861_06375	COG3964	amidohydrolase
PI861_06395	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
PI861_06400	COG1660	Displays ATPase and GTPase activities
PI861_06405	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
PI861_06415	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
PI861_06420	COG1137	ATPase activity
PI861_06425	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
PI861_06430	COG3117	lipopolysaccharide transmembrane transporter activity
PI861_06435	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
PI861_06440	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
PI861_06440	COG0517	IMP dehydrogenase activity
PI861_06445	COG1127	ABC transporter
PI861_06450	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
PI861_06455	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
PI861_06460	COG2854	intermembrane phospholipid transfer
PI861_06470	COG5007	Belongs to the BolA IbaG family
PI861_06475	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
PI861_06480	COG0312	modulator of DNA gyrase
PI861_06485	COG3028	Belongs to the UPF0307 family
PI861_06495	COG2926	Belongs to the UPF0265 family
PI861_06520	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
PI861_06525	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
PI861_06530	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
PI861_06535	COG0049	tRNA binding
PI861_06540	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
PI861_06545	COG2168	tRNA wobble position uridine thiolation
PI861_06550	COG2923	Belongs to the DsrF TusC family
PI861_06565	COG2964	Protein conserved in bacteria
PI861_06570	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
PI861_06575	COG0085	RNA polymerase activity
PI861_06580	COG0222	ribosome binding
PI861_06585	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
PI861_06590	COG0081	regulation of translation
PI861_06595	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
PI861_06600	COG0250	Participates in transcription elongation, termination and antitermination
PI861_06615	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
PI861_06640	COG0812	UDP-N-acetylmuramate dehydrogenase activity
PI861_06645	COG0569	domain protein
PI861_06650	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
PI861_06655	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
PI861_06660	COG3005	denitrification pathway
PI861_06665	COG0243	molybdopterin cofactor binding
PI861_06695	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
PI861_06700	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
PI861_06710	COG2204	response regulator
PI861_06720	COG2205	protein histidine kinase activity
PI861_06735	COG1028	Short-chain dehydrogenase reductase Sdr
PI861_06740	COG0517	IMP dehydrogenase activity
PI861_06740	COG0617	tRNA 3'-terminal CCA addition
PI861_06740	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
PI861_06755	COG1522	sequence-specific DNA binding
PI861_06760	COG2502	aspartate--ammonia ligase
PI861_06765	COG0542	response to heat
PI861_06775	COG0564	pseudouridine synthase activity
PI861_06780	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
PI861_06785	COG0446	pyridine nucleotide-disulphide oxidoreductase
PI861_06795	COG3681	Belongs to the UPF0597 family
PI861_06800	COG2964	Protein conserved in bacteria
PI861_06810	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
PI861_06815	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
PI861_06820	COG1979	alcohol dehydrogenase
PI861_06825	COG2207	Transcriptional regulator
PI861_06830	COG3040	lipid binding
PI861_06840	COG0688	phosphatidylethanolamine metabolic process
PI861_06855	COG0540	Belongs to the ATCase OTCase family
PI861_06860	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
PI861_06865	COG1438	arginine binding
PI861_06870	COG1288	antiporter activity
PI861_06875	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
PI861_06930	COG1609	Transcriptional regulator
PI861_06935	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
PI861_06945	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
PI861_06950	COG2017	converts alpha-aldose to the beta-anomer
PI861_06955	COG0667	Aldo Keto reductase
PI861_06960	COG1968	undecaprenyl-diphosphatase activity
PI861_06970	COG1595	DNA-templated transcription, initiation
PI861_06980	COG0018	arginyl-trna synthetase
PI861_06990	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
PI861_06995	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
PI861_07010	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
PI861_07025	COG2116	formate transmembrane transporter activity
PI861_07030	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
PI861_07030	COG1648	precorrin-2 dehydrogenase activity
PI861_07035	COG2239	Acts as a magnesium transporter
PI861_07050	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
PI861_07055	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
PI861_07065	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
PI861_07075	COG0514	ATP-dependent DNA helicase (RecQ)
PI861_07080	COG2050	protein possibly involved in aromatic compounds catabolism
PI861_07095	COG2258	MOSC domain
PI861_07100	COG1177	transmembrane transport
PI861_07105	COG1176	ABC-type spermidine putrescine transport system, permease component I
PI861_07110	COG3842	ATPase activity
PI861_07130	COG0174	glutamine synthetase
PI861_07145	COG3045	CreA protein
PI861_07150	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
PI861_07155	COG0443	Heat shock 70 kDa protein
PI861_07170	COG0366	Alpha amylase catalytic
PI861_07175	COG1086	Polysaccharide biosynthesis protein
PI861_07195	COG1442	glycosyl transferase family 8
PI861_07215	COG0318	PFAM AMP-dependent synthetase and ligase
PI861_07235	COG1083	cytidylyl-transferase
PI861_07245	COG2089	acid synthase
PI861_07315	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
PI861_07320	COG0745	RESPONSE REGULATOR receiver
PI861_07325	COG2205	protein histidine kinase activity
PI861_07335	COG0281	malic enzyme
PI861_07340	COG0702	epimerase
PI861_07345	COG0254	rRNA binding
PI861_07350	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
PI861_07360	COG1309	transcriptional regulator
PI861_07380	COG0129	dihydroxy-acid dehydratase activity
PI861_07390	COG3978	acetolactate synthase activity
PI861_07405	COG0204	Acyl-transferase
PI861_07410	COG1683	Conserved Protein
PI861_07420	COG1335	isochorismatase
PI861_07430	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
PI861_07435	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
PI861_07440	COG3639	organic phosphonate transmembrane transporter activity
PI861_07445	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
PI861_07450	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
PI861_07460	COG3084	Protein conserved in bacteria
PI861_07465	COG2203	Gaf domain
PI861_07465	COG3706	GGDEF domain
PI861_07465	COG4251	negative regulation of phosphorylation
PI861_07465	COG5001	Diguanylate cyclase
PI861_07480	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
PI861_07490	COG1561	YicC-like family, N-terminal region
PI861_07520	COG0438	transferase activity, transferring glycosyl groups
PI861_07525	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
PI861_07540	COG1063	alcohol dehydrogenase
PI861_07555	COG0210	DNA helicase
PI861_07560	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
PI861_07565	COG2166	iron-sulfur cluster assembly
PI861_07570	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
PI861_07600	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
PI861_07605	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
PI861_07610	COG1739	Uncharacterized protein family UPF0029
PI861_07615	COG0006	proline dipeptidase activity
PI861_07620	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
PI861_07625	COG1024	Enoyl-CoA hydratase
PI861_07625	COG1250	3-hydroxyacyl-CoA dehydrogenase
PI861_07630	COG0183	Belongs to the thiolase family
PI861_07660	COG0425	Belongs to the sulfur carrier protein TusA family
PI861_07665	COG0251	oxidation-reduction process
PI861_07670	COG2885	chlorophyll binding
PI861_07675	COG2818	Glycosylase
PI861_07680	COG0752	glycyl-tRNA synthetase alpha subunit
PI861_07685	COG0751	glycine-tRNA ligase activity
PI861_07695	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
PI861_07705	COG2202	Pas domain
PI861_07705	COG2199	diguanylate cyclase activity
PI861_07705	COG2200	EAL domain
PI861_07720	COG0814	amino acid
PI861_07725	COG0348	domain, Protein
PI861_07735	COG0446	pyridine nucleotide-disulphide oxidoreductase
PI861_07740	COG0426	domain, Protein
PI861_07740	COG1773	rubredoxin
PI861_07745	COG3604	Transcriptional regulator
PI861_07750	COG2188	Transcriptional regulator
PI861_07765	COG1609	Transcriptional regulator
PI861_07805	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
PI861_07830	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
PI861_07845	COG3118	belongs to the thioredoxin family
PI861_07850	COG0513	Belongs to the DEAD box helicase family
PI861_07855	COG0248	Ppx GppA phosphatase
PI861_07865	COG0742	ribosomal rna small subunit methyltransferase
PI861_07870	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
PI861_07890	COG0084	hydrolase, TatD family'
PI861_07895	COG0805	protein transport
PI861_07900	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
PI861_07910	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
PI861_07915	COG3165	ubiquinone biosynthetic process from chorismate
PI861_07925	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
PI861_07970	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
PI861_07975	COG0848	biopolymer transport protein
PI861_07980	COG0811	peptide transport
PI861_07985	COG0811	peptide transport
PI861_07995	COG2771	luxR family
PI861_08010	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
PI861_08025	COG1484	DNA-dependent DNA replication
PI861_08030	COG4584	PFAM Integrase catalytic
PI861_08035	COG0732	type I restriction modification DNA specificity domain
PI861_08090	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
PI861_08095	COG1349	DNA-binding transcription factor activity
PI861_08100	COG0745	RESPONSE REGULATOR receiver
PI861_08105	COG2205	protein histidine kinase activity
PI861_08115	COG4452	Inner membrane protein CreD
PI861_08120	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
PI861_08125	COG0355	proton-transporting ATP synthase activity, rotational mechanism
PI861_08130	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
PI861_08135	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
PI861_08140	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
PI861_08145	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
PI861_08150	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
PI861_08160	COG0356	it plays a direct role in the translocation of protons across the membrane
PI861_08165	COG3312	ion transport
PI861_08170	COG1475	DNA binding
PI861_08175	COG1192	Involved in chromosome partitioning
PI861_08180	COG0357	Ribosomal RNA small subunit methyltransferase G
PI861_08185	COG0445	tRNA wobble uridine modification
PI861_08190	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
PI861_08195	COG4774	siderophore transport
PI861_08200	COG4615	Cyclic peptide transporter
PI861_08205	COG1120	ATPase activity
PI861_08210	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
PI861_08220	COG4774	siderophore transport
PI861_08225	COG4607	ABC-type enterochelin transport system periplasmic component
PI861_08230	COG4604	ABC transporter, ATP-binding protein
PI861_08235	COG4605	iron ion homeostasis
PI861_08240	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
PI861_08245	COG1132	(ABC) transporter
PI861_08250	COG1132	(ABC) transporter
PI861_08250	COG2375	cellular response to nickel ion
PI861_08260	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
PI861_08275	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
PI861_08290	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
PI861_08295	COG0706	membrane insertase activity
PI861_08300	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
PI861_08305	COG0594	ribonuclease P activity
PI861_08310	COG0230	Belongs to the bacterial ribosomal protein bL34 family
PI861_08315	COG1126	abc transporter atp-binding protein
PI861_08330	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
PI861_08335	COG0592	DNA-directed DNA polymerase activity
PI861_08360	COG2378	regulation of single-species biofilm formation
PI861_08365	COG0071	Belongs to the small heat shock protein (HSP20) family
PI861_08370	COG0071	Belongs to the small heat shock protein (HSP20) family
PI861_08395	COG3977	Valine--pyruvate aminotransferase
PI861_08420	COG0745	RESPONSE REGULATOR receiver
PI861_08425	COG2205	protein histidine kinase activity
PI861_08445	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
PI861_08450	COG4191	Histidine kinase
PI861_08450	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
PI861_08455	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
PI861_08460	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
PI861_08465	COG1309	transcriptional regulator
PI861_08495	COG0561	phosphatase activity
PI861_08500	COG2267	carboxylic ester hydrolase activity
PI861_08505	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
PI861_08510	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
PI861_08515	COG1758	RNA polymerase activity
PI861_08520	COG0194	GDP metabolic process
PI861_08525	COG0859	PFAM glycosyl transferase family 9
PI861_08530	COG3642	lipopolysaccharide core region biosynthetic process
PI861_08570	COG0589	response to stress
PI861_08575	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
PI861_08580	COG3706	GGDEF domain
PI861_08590	COG1528	Iron-storage protein
PI861_08595	COG2081	HI0933 family
PI861_08625	COG3188	usher protein
PI861_08645	COG4584	PFAM Integrase catalytic
PI861_08650	COG1484	DNA-dependent DNA replication
PI861_08665	COG2197	response regulator
PI861_08670	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
PI861_08670	COG2205	protein histidine kinase activity
PI861_08680	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
PI861_08680	COG2205	protein histidine kinase activity
PI861_08690	COG3275	phosphorelay sensor kinase activity
PI861_08695	COG3279	Response regulator of the LytR AlgR family
PI861_08700	COG2223	nitrite transmembrane transporter activity
PI861_08705	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
PI861_08710	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
PI861_08725	COG0583	DNA-binding transcription factor activity
PI861_08730	COG4206	TonB-dependent receptor
PI861_08735	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
PI861_08780	COG0583	DNA-binding transcription factor activity
PI861_08785	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
PI861_08790	COG0166	Belongs to the GPI family
PI861_08800	COG0668	transmembrane transport
PI861_08805	COG1309	transcriptional regulator
PI861_08810	COG0756	dUTP diphosphatase activity
PI861_08815	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
PI861_08820	COG2003	Belongs to the UPF0758 family
PI861_08825	COG0227	Belongs to the bacterial ribosomal protein bL28 family
PI861_08830	COG0267	Belongs to the bacterial ribosomal protein bL33 family
PI861_08840	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
PI861_08845	COG2990	Protein conserved in bacteria
PI861_08850	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
PI861_08855	COG0859	PFAM glycosyl transferase family 9
PI861_08860	COG0463	Glycosyl transferase, family 2
PI861_08865	COG0859	PFAM glycosyl transferase family 9
PI861_08870	COG1519	Transferase
PI861_08885	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
PI861_08890	COG1609	Transcriptional regulator
PI861_08915	COG1580	Controls the rotational direction of flagella during chemotaxis
PI861_08920	COG3161	chorismate lyase activity
PI861_08925	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
PI861_08930	COG2937	Belongs to the GPAT DAPAT family
PI861_08935	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
PI861_08955	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
PI861_08960	COG2205	protein histidine kinase activity
PI861_08965	COG0745	RESPONSE REGULATOR receiver
PI861_08975	COG1045	serine acetyltransferase
PI861_08985	COG3074	FtsZ-dependent cytokinesis
PI861_08990	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
PI861_09000	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
PI861_09050	COG0385	Bile acid
PI861_09055	COG1262	PFAM Formylglycine-generating sulfatase enzyme
PI861_09075	COG0583	DNA-binding transcription factor activity
PI861_09080	COG1079	Belongs to the binding-protein-dependent transport system permease family
PI861_09085	COG4603	Belongs to the binding-protein-dependent transport system permease family
PI861_09090	COG3845	ABC transporter
PI861_09100	COG1744	ABC transporter substrate-binding protein PnrA-like
PI861_09105	COG0210	DNA helicase
PI861_09145	COG2823	Periplasmic or secreted lipoprotein
PI861_09165	COG0583	DNA-binding transcription factor activity
PI861_09170	COG1280	lysine exporter protein (LysE YggA)
PI861_09175	COG2391	methyltransferase activity
PI861_09185	COG1280	lysine exporter protein (LysE YggA)
PI861_09195	COG2962	Rard protein
PI861_09205	COG1012	belongs to the aldehyde dehydrogenase family
PI861_09215	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
PI861_09225	COG0518	GMP synthase (glutamine-hydrolyzing) activity
PI861_09225	COG0519	Catalyzes the synthesis of GMP from XMP
PI861_09230	COG0686	Belongs to the AlaDH PNT family
PI861_09235	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
PI861_09260	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
PI861_09265	COG0569	domain protein
PI861_09270	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
PI861_09270	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
PI861_09275	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
PI861_09280	COG0242	peptide deformylase activity
PI861_09285	COG1652	LysM domain
PI861_09290	COG0758	DNA mediated transformation
PI861_09295	COG2922	Belongs to the Smg family
PI861_09300	COG0551	DNA topoisomerase type I activity
PI861_09310	COG0009	L-threonylcarbamoyladenylate synthase
PI861_09315	COG0408	coproporphyrinogen oxidase activity
PI861_09320	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
PI861_09330	COG0218	Necessary for normal cell division and for the maintenance of normal septation
PI861_09340	COG3078	GTPase activator activity
PI861_09350	COG0635	Involved in the biosynthesis of porphyrin-containing compound
PI861_09355	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
PI861_09360	COG2204	response regulator
PI861_09365	COG3852	Histidine kinase
PI861_09375	COG0174	glutamine synthetase
PI861_09380	COG1217	gtp-binding protein TYPA
PI861_09385	COG1295	ribonuclease BN
PI861_09400	COG0456	acetyltransferase
PI861_09410	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
PI861_09415	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
PI861_09420	COG2610	gluconate transmembrane transporter activity
PI861_09425	COG3265	gluconokinase activity
PI861_09430	COG0129	dihydroxy-acid dehydratase activity
PI861_09435	COG0800	Aldolase
PI861_09440	COG1609	Transcriptional regulator
PI861_09450	COG4942	peptidase
PI861_09455	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
PI861_09460	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
PI861_09465	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
PI861_09470	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
PI861_09475	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
PI861_09475	COG0316	Belongs to the HesB IscA family
PI861_09480	COG1040	competence protein
PI861_09485	COG0596	Alpha beta hydrolase
PI861_09505	COG2183	response to ionizing radiation
PI861_09510	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
PI861_09530	COG0051	transcription antitermination factor activity, RNA binding
PI861_09535	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
PI861_09540	COG0088	Forms part of the polypeptide exit tunnel
PI861_09545	COG0089	rRNA binding
PI861_09550	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
PI861_09555	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
PI861_09560	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
PI861_09565	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
PI861_09570	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
PI861_09575	COG0255	Belongs to the universal ribosomal protein uL29 family
PI861_09580	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
PI861_09585	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
PI861_09590	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
PI861_09595	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
PI861_09600	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
PI861_09605	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
PI861_09610	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
PI861_09615	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
PI861_09620	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
PI861_09625	COG1841	ribosomal large subunit assembly
PI861_09630	COG0200	Binds to the 23S rRNA
PI861_09635	COG0201	protein transport
PI861_09640	COG0257	Belongs to the bacterial ribosomal protein bL36 family
PI861_09645	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
PI861_09650	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
PI861_09655	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
PI861_09660	COG0202	RNA polymerase activity
PI861_09665	COG0203	ribosomal protein L17
PI861_09715	COG1484	DNA-dependent DNA replication
PI861_09720	COG4584	PFAM Integrase catalytic
PI861_09730	COG2376	Dihydroxyacetone kinase
PI861_09735	COG1461	Dihydroxyacetone kinase
PI861_09740	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
PI861_09740	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
PI861_09740	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
PI861_09750	COG3284	Transcriptional regulator
PI861_09755	COG0628	permease
PI861_09760	COG0494	nUDIX hydrolase
PI861_09785	COG0753	catalase activity
PI861_09810	COG2199	diguanylate cyclase activity
PI861_09810	COG2203	Gaf domain
PI861_09820	COG3842	ATPase activity
PI861_09830	COG1176	ABC-type spermidine putrescine transport system, permease component I
PI861_09865	COG1741	Belongs to the pirin family
PI861_09870	COG2259	Doxx family
PI861_09875	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
PI861_09880	COG1074	ATP-dependent DNA helicase activity
PI861_09885	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
PI861_09895	COG0346	lactoylglutathione lyase activity
PI861_09910	COG0004	ammonium transporteR
PI861_09915	COG0347	Belongs to the P(II) protein family
PI861_09930	COG0840	transmembrane signaling receptor activity
PI861_09960	COG3706	GGDEF domain
PI861_09965	COG4771	TonB-dependent receptor
PI861_09970	COG1278	Cold shock
PI861_09975	COG2199	diguanylate cyclase activity
PI861_09980	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
PI861_09985	COG2197	response regulator
PI861_10005	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
PI861_10040	COG2249	NAD(P)H dehydrogenase (quinone) activity
PI861_10055	COG1770	oligopeptidase
PI861_10075	COG3714	YhhN family
PI861_10100	COG1301	dicarboxylic acid transport
PI861_10110	COG2095	MarC family integral membrane protein
PI861_10120	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
PI861_10130	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
PI861_10140	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
PI861_10165	COG0742	ribosomal rna small subunit methyltransferase
PI861_10170	COG0552	protein localization to endoplasmic reticulum
PI861_10175	COG2884	Cell division ATP-binding protein ftsE
PI861_10180	COG2177	Part of the ABC transporter FtsEX involved in
PI861_10190	COG0288	reversible hydration of carbon dioxide
PI861_10195	COG2188	Transcriptional regulator
PI861_10200	COG1228	amidohydrolase
PI861_10205	COG0010	Belongs to the arginase family
PI861_10210	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
PI861_10215	COG2986	histidine ammonia-lyase
PI861_10220	COG0387	Pfam Sodium calcium exchanger
PI861_10225	COG2264	protein methyltransferase activity
PI861_10230	COG2199	diguanylate cyclase activity
PI861_10230	COG2200	EAL domain
PI861_10290	COG1077	Cell shape determining protein MreB Mrl
PI861_10295	COG1792	Involved in formation and maintenance of cell shape
PI861_10300	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
PI861_10305	COG0424	maF-like protein
PI861_10310	COG1530	ribonuclease E activity
PI861_10315	COG3164	Protein of unknown function
PI861_10325	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
PI861_10330	COG0312	modulator of DNA gyrase
PI861_10355	COG3437	response regulator, receiver
PI861_10360	COG0784	Response regulator, receiver
PI861_10360	COG2205	protein histidine kinase activity
PI861_10360	COG5002	protein histidine kinase activity
PI861_10365	COG2172	sigma factor antagonist activity
PI861_10370	COG1366	Belongs to the anti-sigma-factor antagonist family
PI861_10380	COG3700	Belongs to the class B bacterial acid phosphatase family
PI861_10390	COG1639	'signal transduction protein
PI861_10415	COG0189	ligase activity
PI861_10420	COG0642	Histidine kinase
PI861_10425	COG0745	RESPONSE REGULATOR receiver
PI861_10445	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
PI861_10450	COG0352	thiamine-phosphate diphosphorylase activity
PI861_10455	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
PI861_10465	COG2022	thiamine diphosphate biosynthetic process
PI861_10490	COG0110	maltose O-acetyltransferase activity
PI861_10495	COG3417	Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1B (PBP1b)
PI861_10510	COG0814	amino acid
PI861_10515	COG3932	Exopolysaccharide synthesis, ExoD
PI861_10530	COG1733	regulation of RNA biosynthetic process
PI861_10570	COG1494	fructose-1,6-bisphosphatase
PI861_10585	COG2959	enzyme of heme biosynthesis
PI861_10595	COG0181	hydroxymethylbilane synthase activity
PI861_10600	COG3072	Adenylate cyclase
PI861_10620	COG1965	Belongs to the frataxin family
PI861_10630	COG0019	diaminopimelate decarboxylase activity
PI861_10635	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
PI861_10650	COG1011	Hydrolase
PI861_10660	COG0668	transmembrane transport
PI861_10670	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
PI861_10675	COG0561	phosphatase activity
PI861_10690	COG0842	Transport permease protein
PI861_10690	COG1129	ABC transporter
PI861_10700	COG1546	Belongs to the CinA family
PI861_10700	COG1058	Belongs to the CinA family
PI861_10705	COG1418	mRNA catabolic process
PI861_10710	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
PI861_10720	COG1522	sequence-specific DNA binding
PI861_10725	COG1368	sulfuric ester hydrolase activity
PI861_10745	COG1285	pathogenesis
PI861_10765	COG4221	oxidoreductase activity
PI861_10785	COG1979	alcohol dehydrogenase
PI861_10795	COG2873	o-acetylhomoserine
PI861_10805	COG4533	DNA binding
PI861_10810	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
PI861_10825	COG5380	lipid catabolic process
PI861_10830	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
PI861_10840	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
PI861_10845	COG2949	membrane
PI861_10850	COG3291	Pkd domain containing protein
PI861_10860	COG3539	Fimbrial protein
PI861_10870	COG3188	usher protein
PI861_10875	COG3121	Chaperone
PI861_10880	COG3539	Fimbrial protein
PI861_10900	COG0318	PFAM AMP-dependent synthetase and ligase
PI861_10910	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
PI861_10915	COG0596	Alpha beta hydrolase
PI861_10920	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
PI861_10925	COG1169	isochorismate synthase
PI861_10930	COG1575	Belongs to the MenA family. Type 1 subfamily
PI861_10960	COG0513	Belongs to the DEAD box helicase family
PI861_10965	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
PI861_10970	COG1988	membrane-bound metal-dependent
PI861_10985	COG1671	Belongs to the UPF0178 family
PI861_11005	COG0484	heat shock protein binding
PI861_11010	COG3263	regulation of cellular component size
PI861_11015	COG3722	fumarate hydratase activity
PI861_11020	COG0246	Mannitol dehydrogenase
PI861_11025	COG2213	PTS system mannitol-specific
PI861_11025	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
PI861_11040	COG4776	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction
PI861_11055	COG2771	luxR family
PI861_11070	COG3133	Outer membrane lipoprotein
PI861_11075	COG0456	acetyltransferase
PI861_11095	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
PI861_11100	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
PI861_11120	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
PI861_11125	COG1459	type II secretion system
PI861_11130	COG2165	general secretion pathway protein
PI861_11140	COG2165	general secretion pathway protein
PI861_11145	COG4795	General secretion pathway protein
PI861_11150	COG3156	type II secretion system protein K
PI861_11160	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
PI861_11175	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
PI861_11180	COG1011	Hydrolase
PI861_11185	COG0494	nUDIX hydrolase
PI861_11190	COG1218	3'(2'),5'-bisphosphate nucleotidase
PI861_11195	COG0814	amino acid
PI861_11200	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
PI861_11215	COG0626	cystathionine gamma-synthase activity
PI861_11220	COG0460	homoserine dehydrogenase
PI861_11220	COG0527	aspartate kinase activity
PI861_11235	COG1346	cytolysis
PI861_11240	COG1380	Effector of murein hydrolase LrgA
PI861_11275	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
PI861_11280	COG1546	Belongs to the CinA family
PI861_11285	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
PI861_11295	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
PI861_11300	COG0527	aspartate kinase activity
PI861_11305	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
PI861_11330	COG1686	Belongs to the peptidase S11 family
PI861_11335	COG0586	Pfam SNARE associated Golgi protein
PI861_11340	COG1253	flavin adenine dinucleotide binding
PI861_11350	COG2927	DNA polymerase III (CHI subunit)
PI861_11355	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
PI861_11360	COG0795	lipopolysaccharide-transporting ATPase activity
PI861_11365	COG0795	lipopolysaccharide-transporting ATPase activity
PI861_11510	COG4695	Portal protein
PI861_11595	COG2932	Transcriptional regulator
PI861_11600	COG4974	Belongs to the 'phage' integrase family
PI861_11605	COG0582	viral genome integration into host DNA
PI861_11625	COG3561	AntA/AntB antirepressor
PI861_11675	COG0004	ammonium transporteR
PI861_11680	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
PI861_11695	COG2165	general secretion pathway protein
PI861_11700	COG0084	hydrolase, TatD family'
PI861_11705	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
PI861_11715	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
PI861_11720	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
PI861_11725	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
PI861_11730	COG0813	purine-nucleoside phosphorylase activity
PI861_11740	COG0560	Phosphoserine phosphatase
PI861_11765	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
PI861_11770	COG0776	regulation of translation
PI861_11785	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
PI861_11790	COG0735	belongs to the Fur family
PI861_11810	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
PI861_11815	COG0513	Belongs to the DEAD box helicase family
PI861_11820	COG3022	response to hydroperoxide
PI861_11835	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
PI861_11840	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
PI861_11845	COG0762	integral membrane protein
PI861_11850	COG1872	DUF167
PI861_11865	COG4166	transmembrane transport
PI861_11875	COG0110	maltose O-acetyltransferase activity
PI861_11885	COG1024	Enoyl-CoA hydratase
PI861_11900	COG4221	oxidoreductase activity
PI861_11910	COG2957	Belongs to the agmatine deiminase family
PI861_11935	COG0513	Belongs to the DEAD box helicase family
PI861_11955	COG1912	Pfam S-adenosyl-l-methionine hydroxide adenosyltransferase
PI861_12020	COG2816	NAD+ diphosphatase activity
PI861_12025	COG2205	protein histidine kinase activity
PI861_12030	COG0745	RESPONSE REGULATOR receiver
PI861_12035	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
PI861_12040	COG0577	efflux transmembrane transporter activity
PI861_12040	COG1136	(ABC) transporter
PI861_12045	COG1505	serine-type exopeptidase activity
PI861_12050	COG2982	Protein involved in outer membrane biogenesis
PI861_12070	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
PI861_12075	COG3730	PTS system glucitol sorbitol-specific
PI861_12090	COG1028	Short-chain dehydrogenase reductase Sdr
PI861_12100	COG1349	DNA-binding transcription factor activity
PI861_12105	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
PI861_12120	COG0494	nUDIX hydrolase
PI861_12125	COG2130	NADP-dependent
PI861_12130	COG1764	response to oxidative stress
PI861_12135	COG1846	Transcriptional regulator
PI861_12165	COG0561	phosphatase activity
PI861_12180	COG0733	neurotransmitter:sodium symporter activity
PI861_12190	COG0733	neurotransmitter:sodium symporter activity
PI861_12230	COG1794	racemase activity, acting on amino acids and derivatives
PI861_12240	COG2731	YhcH YjgK YiaL family protein
PI861_12250	COG0668	transmembrane transport
PI861_12255	COG1376	ErfK ybiS ycfS ynhG family protein
PI861_12260	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
PI861_12270	COG0789	Transcriptional regulator
PI861_12335	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
PI861_12345	COG0488	(ABC) transporter
PI861_12350	COG0517	IMP dehydrogenase activity
PI861_12350	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
PI861_12355	COG1585	Membrane protein implicated in regulation of membrane protease activity
PI861_12360	COG0330	HflC and HflK could
PI861_12365	COG1648	precorrin-2 dehydrogenase activity
PI861_12365	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
PI861_12370	COG0175	sulfate reduction
PI861_12375	COG2895	sulfate adenylyltransferase (ATP) activity
PI861_12380	COG0471	metal ion transport
PI861_12380	COG3273	potassium ion transport
PI861_12385	COG0529	Catalyzes the synthesis of activated sulfate
PI861_12400	COG0840	transmembrane signaling receptor activity
PI861_12420	COG1136	(ABC) transporter
PI861_12435	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
PI861_12450	COG1940	carbohydrate kinase activity
PI861_12455	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
PI861_12460	COG0126	phosphoglycerate kinase activity
PI861_12465	COG0191	fructose-bisphosphate aldolase activity
PI861_12470	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
PI861_12520	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
PI861_12525	COG1595	DNA-templated transcription, initiation
PI861_12530	COG3073	An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E
PI861_12545	COG0481	GTPase activity
PI861_12555	COG0571	ribonuclease III activity
PI861_12565	COG1381	Involved in DNA repair and RecF pathway recombination
PI861_12570	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
PI861_12575	COG3023	N-Acetylmuramoyl-L-alanine amidase
PI861_12580	COG4807	Protein conserved in bacteria
PI861_12590	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
PI861_12595	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
PI861_12600	COG3956	TIGRFAM MazG family protein
PI861_12605	COG0504	CTP synthase activity
PI861_12610	COG0148	phosphopyruvate hydratase activity
PI861_12615	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
PI861_12620	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
PI861_12630	COG0585	pseudouridine synthase activity
PI861_12635	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
PI861_12640	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
PI861_12645	COG1238	metal cluster binding
PI861_12650	COG1388	LysM domain
PI861_12650	COG4942	peptidase
PI861_12660	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
PI861_12665	COG0828	Belongs to the bacterial ribosomal protein bS21 family
PI861_12670	COG1610	YqeY-like protein
PI861_12680	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
PI861_12720	COG0151	Belongs to the GarS family
PI861_12725	COG0138	bifunctional purine biosynthesis protein purh
PI861_12735	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
PI861_12740	COG3036	rescue of stalled ribosome
PI861_12745	COG0635	Involved in the biosynthesis of porphyrin-containing compound
PI861_12750	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
PI861_12775	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
PI861_12780	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
PI861_12795	COG0477	Major facilitator Superfamily
PI861_12805	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
PI861_12810	COG1027	Aspartate ammonia-lyase
PI861_12815	COG3030	protein affecting phage T7 exclusion by the F plasmid
PI861_12820	COG0534	Mate efflux family protein
PI861_12825	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
PI861_12830	COG0459	protein refolding
PI861_12840	COG3300	MHYT domain
PI861_12840	COG5001	Diguanylate cyclase
PI861_12850	COG0564	pseudouridine synthase activity
PI861_12855	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
PI861_12885	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
PI861_12895	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
PI861_12900	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
PI861_12905	COG1178	ABC-type Fe3 transport system permease component
PI861_12910	COG4143	(ABC) transporter
PI861_12925	COG0066	3-isopropylmalate dehydratase activity
PI861_12930	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
PI861_12935	COG0473	3-isopropylmalate dehydrogenase activity
PI861_12940	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
PI861_12950	COG0671	phosphoesterase, PA-phosphatase related
PI861_12965	COG0028	Belongs to the TPP enzyme family
PI861_12970	COG0440	acetolactate synthase activity
PI861_12975	COG0280	phosphate acetyltransferase
PI861_12975	COG0857	belongs to the CobB CobQ family
PI861_12980	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
PI861_12990	COG3013	Belongs to the UPF0304 family
PI861_12995	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
PI861_13000	COG2716	regulation of RNA biosynthetic process
PI861_13010	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
PI861_13015	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
PI861_13050	COG0784	Response regulator, receiver
PI861_13050	COG2198	Histidine kinase
PI861_13050	COG5002	protein histidine kinase activity
PI861_13065	COG2205	protein histidine kinase activity
PI861_13065	COG3437	response regulator, receiver
PI861_13065	COG3850	Histidine kinase
PI861_13065	COG4999	Histidine kinase
PI861_13080	COG0840	transmembrane signaling receptor activity
PI861_13090	COG1464	Belongs to the NlpA lipoprotein family
PI861_13095	COG2011	ABC-type metal ion transport system permease component
PI861_13120	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
PI861_13120	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
PI861_13125	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
PI861_13125	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
PI861_13130	COG0802	atpase or kinase
PI861_13145	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
PI861_13150	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
PI861_13155	COG1923	regulation of RNA biosynthetic process
PI861_13160	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
PI861_13165	COG0330	HflC and HflK could
PI861_13170	COG0330	HflC and HflK could
PI861_13175	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
PI861_13180	COG0142	geranyltranstransferase activity
PI861_13185	COG0261	This protein binds to 23S rRNA in the presence of protein L20
PI861_13190	COG0211	Belongs to the bacterial ribosomal protein bL27 family
PI861_13195	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
PI861_13200	COG3314	Sporulation integral membrane protein YlbJ
PI861_13205	COG0318	PFAM AMP-dependent synthetase and ligase
PI861_13215	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
PI861_13225	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
PI861_13240	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
PI861_13245	COG2967	ApaG domain
PI861_13250	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
PI861_13255	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
PI861_13265	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
PI861_13270	COG3178	'Phosphotransferase
PI861_13275	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
PI861_13280	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
PI861_13295	COG0488	(ABC) transporter
PI861_13320	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
PI861_13330	COG3721	Heme iron utilization protein
PI861_13335	COG0748	coenzyme F420 binding
PI861_13355	COG4771	TonB-dependent receptor
PI861_13360	COG2814	Major facilitator Superfamily
PI861_13370	COG3655	Transcriptional regulator
PI861_13395	COG3397	chitin binding
PI861_13410	COG1765	OsmC-like protein
PI861_13425	COG3954	Phosphoribulokinase
PI861_13430	COG2076	Multidrug Resistance protein
PI861_13435	COG2076	Multidrug Resistance protein
PI861_13440	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
PI861_13445	COG0726	polysaccharide deacetylase
PI861_13455	COG0463	Glycosyl transferase, family 2
PI861_13460	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
PI861_13470	COG3089	Belongs to the UPF0270 family
PI861_13475	COG2203	Gaf domain
PI861_13475	COG3706	GGDEF domain
PI861_13475	COG5001	Diguanylate cyclase
PI861_13475	COG4251	negative regulation of phosphorylation
PI861_13480	COG0429	hydrolase of the alpha beta-hydrolase fold
PI861_13485	COG0835	chemotaxis
PI861_13485	COG0784	Response regulator, receiver
PI861_13495	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
PI861_13500	COG1047	Peptidyl-prolyl cis-trans
PI861_13515	COG0545	Peptidyl-prolyl cis-trans isomerase
PI861_13520	COG2204	response regulator
PI861_13540	COG0737	Belongs to the 5'-nucleotidase family
PI861_13545	COG2200	EAL domain
PI861_13565	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
PI861_13570	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
PI861_13575	COG0826	peptidase U32
PI861_13580	COG2199	diguanylate cyclase activity
PI861_13580	COG2200	EAL domain
PI861_13580	COG2203	Gaf domain
PI861_13610	COG2197	response regulator
PI861_13615	COG2197	response regulator
PI861_13645	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
PI861_13650	COG2201	protein-glutamate methylesterase activity
PI861_13655	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
PI861_13665	COG0840	transmembrane signaling receptor activity
PI861_13670	COG0835	chemotaxis
PI861_13680	COG0643	Histidine kinase
PI861_13680	COG2198	Histidine kinase
PI861_13690	COG0745	RESPONSE REGULATOR receiver
PI861_13700	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
PI861_13710	COG1280	lysine exporter protein (LysE YggA)
PI861_13725	COG3813	Protein conserved in bacteria
PI861_13740	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
PI861_13755	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
PI861_13780	COG0300	oxidoreductase activity
PI861_13800	COG2133	pyrroloquinoline quinone binding
PI861_13825	COG0077	Prephenate dehydratase
PI861_13825	COG1605	Chorismate mutase
PI861_13855	COG3272	Protein of unknown function (DUF1722)
PI861_13860	COG0789	Transcriptional regulator
PI861_13865	COG0415	Belongs to the DNA photolyase family
PI861_13875	COG0300	oxidoreductase activity
PI861_13890	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
PI861_13915	COG0783	Belongs to the Dps family
PI861_13920	COG1151	hydroxylamine reductase activity
PI861_13930	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
PI861_13935	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
PI861_13935	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
PI861_13945	COG3459	Glycosyltransferase 36 associated
PI861_13970	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
PI861_13975	COG1666	GTP binding
PI861_13980	COG3248	Nucleoside-binding outer membrane protein
PI861_13985	COG2211	Major facilitator Superfamily
PI861_13995	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
PI861_14005	COG2813	Specifically methylates the guanine in position
PI861_14010	COG0271	Belongs to the BolA IbaG family
PI861_14020	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
PI861_14025	COG1805	sodium ion transport
PI861_14030	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
PI861_14035	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
PI861_14040	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
PI861_14045	COG2871	sodium ion transport
PI861_14050	COG1477	protein flavinylation
PI861_14065	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
PI861_14070	COG0840	transmembrane signaling receptor activity
PI861_14075	COG0583	DNA-binding transcription factor activity
PI861_14085	COG2363	Small membrane protein
PI861_14090	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
PI861_14100	COG0473	3-isopropylmalate dehydrogenase activity
PI861_14105	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
PI861_14110	COG1611	Belongs to the LOG family
PI861_14125	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
PI861_14125	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
PI861_14135	COG5595	Zn-ribbon-containing, possibly nucleic-acid-binding protein (DUF2310)
PI861_14160	COG3098	single-species biofilm formation
PI861_14165	COG0564	pseudouridine synthase activity
PI861_14175	COG4580	involved in the transport of maltose and maltodextrins
PI861_14195	COG1263	PTS System
PI861_14195	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
PI861_14205	COG2171	N-acyltransferase activity
PI861_14215	COG0024	Methionine aminopeptidase
PI861_14220	COG0052	Belongs to the universal ribosomal protein uS2 family
PI861_14225	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
PI861_14230	COG0528	UMP kinase activity
PI861_14235	COG0233	cytoplasmic translational termination
PI861_14240	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
PI861_14245	COG0575	Belongs to the CDS family
PI861_14250	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
PI861_14255	COG0750	zinc metalloprotease
PI861_14270	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
PI861_14275	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
PI861_14280	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
PI861_14285	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
PI861_14290	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
PI861_14300	COG0825	malonyl-CoA metabolic process
PI861_14305	COG3710	Transcriptional regulator
PI861_14310	COG0531	amino acid
PI861_14315	COG1982	Orn Lys Arg decarboxylase major
PI861_14320	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
PI861_14335	COG0814	amino acid
PI861_14340	COG0531	amino acid
PI861_14350	COG0488	(ABC) transporter
PI861_14360	COG3590	peptidase
PI861_14365	COG0037	tRNA processing
PI861_14415	COG0366	Alpha amylase catalytic
PI861_14425	COG1881	PFAM PEBP family protein
PI861_14430	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
PI861_14435	COG0583	DNA-binding transcription factor activity
PI861_14445	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
PI861_14455	COG0583	DNA-binding transcription factor activity
PI861_14460	COG1028	Short-chain dehydrogenase reductase Sdr
PI861_14465	COG0616	signal peptide processing
PI861_14470	COG3724	N-succinylarginine dihydrolase activity
PI861_14490	COG0840	transmembrane signaling receptor activity
PI861_14500	COG2971	BadF BadG BcrA BcrD
PI861_14510	COG4608	Belongs to the ABC transporter superfamily
PI861_14515	COG0444	Belongs to the ABC transporter superfamily
PI861_14520	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
PI861_14525	COG0601	transmembrane transport
PI861_14535	COG0784	Response regulator, receiver
PI861_14535	COG2205	protein histidine kinase activity
PI861_14570	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
PI861_14575	COG1289	transmembrane transporter activity
PI861_14580	COG0303	'Molybdopterin
PI861_14585	COG0746	molybdenum cofactor guanylyltransferase activity
PI861_14595	COG4662	Binding-protein-dependent transport system inner membrane component
PI861_14610	COG3852	Histidine kinase
PI861_14620	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
PI861_14625	COG2801	Transposase and inactivated derivatives
PI861_14655	COG1196	nuclear chromosome segregation
PI861_14655	COG3264	Mechanosensitive ion channel
PI861_14660	COG0469	pyruvate kinase activity
PI861_14680	COG0405	Gamma-glutamyltransferase
PI861_14685	COG2974	May be involved in recombination
PI861_14695	COG0420	3'-5' exonuclease activity
PI861_14700	COG0419	ATPase involved in DNA repair
PI861_14710	COG3038	cytochrome b561
PI861_14725	COG2190	(PTS) system
PI861_14735	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
PI861_14740	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
PI861_14760	COG1720	tRNA m6t6A37 methyltransferase activity
PI861_14780	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
PI861_14785	COG4988	ABC transporter
PI861_14800	COG0745	RESPONSE REGULATOR receiver
PI861_14810	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
PI861_14825	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
PI861_14830	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
PI861_14840	COG0083	homoserine kinase activity
PI861_14845	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
PI861_14875	COG1943	Transposase
PI861_14895	COG0813	purine-nucleoside phosphorylase activity
PI861_14910	COG3384	dioxygenase
PI861_14920	COG1283	sodium-dependent phosphate transmembrane transporter activity
PI861_14925	COG0531	amino acid
PI861_14930	COG0531	amino acid
PI861_14945	COG1396	sequence-specific DNA binding
PI861_14945	COG1917	Cupin 2, conserved barrel domain protein
PI861_14950	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
PI861_14960	COG2169	Transcriptional regulator
PI861_14960	COG1917	Cupin 2, conserved barrel domain protein
PI861_14985	COG2916	Histone family protein nucleoid-structuring protein H-NS
PI861_14990	COG3328	transposase activity
PI861_14995	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
PI861_15000	COG2375	cellular response to nickel ion
PI861_15005	COG1538	Outer membrane efflux protein
PI861_15010	COG0577	efflux transmembrane transporter activity
PI861_15010	COG1136	(ABC) transporter
PI861_15015	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
PI861_15025	COG1227	inorganic diphosphatase activity
PI861_15030	COG0497	DNA recombination
PI861_15035	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
PI861_15040	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
PI861_15045	COG0443	Heat shock 70 kDa protein
PI861_15050	COG0484	heat shock protein binding
PI861_15080	COG1285	pathogenesis
PI861_15125	COG0095	Lipoate-protein ligase
PI861_15135	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
PI861_15140	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
PI861_15165	COG0708	Exodeoxyribonuclease III
PI861_15220	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
PI861_15225	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
PI861_15230	COG1845	cytochrome c oxidase, subunit III
PI861_15235	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
PI861_15240	COG0109	protoheme IX farnesyltransferase activity
PI861_15245	COG2814	Major facilitator Superfamily
PI861_15265	COG1609	Transcriptional regulator
PI861_15270	COG1263	PTS System
PI861_15270	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
PI861_15275	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
PI861_15305	COG2207	Transcriptional regulator
PI861_15310	COG0538	isocitrate dehydrogenase activity
PI861_15320	COG3048	D-serine ammonia-lyase activity
PI861_15325	COG2610	gluconate transmembrane transporter activity
PI861_15330	COG0583	DNA-binding transcription factor activity
PI861_15405	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
PI861_15410	COG2867	negative regulation of translational initiation
PI861_15415	COG2914	Belongs to the UPF0125 (RnfH) family
PI861_15420	COG0702	epimerase
PI861_15425	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
PI861_15460	COG4964	Belongs to the GSP D family
PI861_15470	COG2894	cell division
PI861_15510	COG1454	alcohol dehydrogenase
PI861_15525	COG1957	nucleoside hydrolase
PI861_15545	COG0840	transmembrane signaling receptor activity
PI861_15550	COG1280	lysine exporter protein (LysE YggA)
PI861_15570	COG3263	regulation of cellular component size
PI861_15580	COG1876	peptidase activity
PI861_15585	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
PI861_15590	COG1393	Belongs to the ArsC family
PI861_15595	COG0583	DNA-binding transcription factor activity
PI861_15610	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
PI861_15615	COG0017	Asparaginyl-tRNA synthetase
PI861_15635	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
PI861_15640	COG0156	8-amino-7-oxononanoate synthase activity
PI861_15645	COG2226	methyltransferase
PI861_15645	COG1073	alpha beta
PI861_15650	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
PI861_15655	COG0501	Belongs to the peptidase M48B family
PI861_15665	COG3217	Mosc domain protein beta barrel domain protein
PI861_15665	COG0633	Ferredoxin
PI861_15665	COG0633	Ferredoxin
PI861_15665	COG3217	Mosc domain protein beta barrel domain protein
PI861_15680	COG2841	Protein conserved in bacteria
PI861_15690	COG0534	Mate efflux family protein
PI861_15730	COG1309	transcriptional regulator
PI861_15745	COG0791	NLP P60 protein
PI861_15755	COG0583	DNA-binding transcription factor activity
PI861_15765	COG0450	alkyl hydroperoxide reductase
PI861_15785	COG0500	methyltransferase
PI861_15790	COG4106	trans-aconitate 2-methyltransferase activity
PI861_15800	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
PI861_15805	COG0217	transcriptional regulatory protein
PI861_15825	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
PI861_15835	COG4584	PFAM Integrase catalytic
PI861_15840	COG1484	DNA-dependent DNA replication
PI861_15855	COG3321	synthase
PI861_15855	COG0604	alcohol dehydrogenase
PI861_15870	COG0438	transferase activity, transferring glycosyl groups
PI861_15900	COG1940	carbohydrate kinase activity
PI861_15900	COG1846	Transcriptional regulator
PI861_15905	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
PI861_15910	COG0363	glucosamine-6-phosphate deaminase activity
PI861_15915	COG2190	(PTS) system
PI861_15915	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
PI861_15915	COG1263	PTS System
PI861_15925	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
PI861_15930	COG0735	belongs to the Fur family
PI861_15940	COG0716	FMN binding
PI861_15955	COG0596	Alpha beta hydrolase
PI861_15960	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
PI861_15965	COG0033	Phosphoglucomutase
PI861_15975	COG1846	Transcriptional regulator
PI861_15980	COG2951	lytic endotransglycosylase activity
PI861_15985	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
PI861_15990	COG4136	ATPase activity
PI861_15995	COG4135	transport system, permease component
PI861_16000	COG4134	Bacterial extracellular solute-binding protein
PI861_16005	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
PI861_16010	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
PI861_16020	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
PI861_16025	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
PI861_16040	COG0729	surface antigen
PI861_16045	COG2911	Protein conserved in bacteria
PI861_16060	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
PI861_16085	COG1607	acyl-coa hydrolase
PI861_16090	COG3021	interspecies interaction between organisms
PI861_16095	COG1388	LysM domain
PI861_16095	COG0741	lytic transglycosylase activity
PI861_16100	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
PI861_16105	COG2226	methyltransferase
PI861_16110	COG0328	RNA-DNA hybrid ribonuclease activity
PI861_16115	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
PI861_16125	COG0784	Response regulator, receiver
PI861_16125	COG3437	response regulator, receiver
PI861_16130	COG1960	acyl-CoA dehydrogenase activity
PI861_16135	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
PI861_16140	COG0121	glutamine amidotransferase
PI861_16170	COG2197	response regulator
PI861_16175	COG3850	Histidine kinase
PI861_16180	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
PI861_16185	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
PI861_16195	COG0243	molybdopterin cofactor binding
PI861_16200	COG0437	4 iron, 4 sulfur cluster binding
PI861_16205	COG0348	domain, Protein
PI861_16215	COG3005	denitrification pathway
PI861_16220	COG0521	Mo-molybdopterin cofactor biosynthetic process
PI861_16225	COG0315	cyclic pyranopterin monophosphate synthase activity
PI861_16230	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
PI861_16235	COG0314	molybdopterin synthase activity
PI861_16250	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
PI861_16255	COG0596	Alpha beta hydrolase
PI861_16280	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
PI861_16290	COG0302	gtp cyclohydrolase
PI861_16295	COG0840	transmembrane signaling receptor activity
PI861_16300	COG2759	Belongs to the formate--tetrahydrofolate ligase family
PI861_16310	COG0583	DNA-binding transcription factor activity
PI861_16315	COG2353	YceI-like domain
PI861_16340	COG2195	Cleaves the N-terminal amino acid of tripeptides
PI861_16345	COG1166	arginine decarboxylase activity
PI861_16375	COG0346	lactoylglutathione lyase activity
PI861_16385	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
PI861_16395	COG1187	pseudouridine synthase activity
PI861_16400	COG2807	transmembrane transport
PI861_16410	COG0583	DNA-binding transcription factor activity
PI861_16430	COG2979	Protein of unknown function (DUF533)
PI861_16435	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
PI861_16445	COG1294	oxidase, subunit
PI861_16455	COG2814	Major facilitator Superfamily
PI861_16460	COG0656	L-ascorbic acid biosynthetic process
PI861_16465	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
PI861_16495	COG0583	DNA-binding transcription factor activity
PI861_16500	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
PI861_16505	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
PI861_16510	COG2271	Major facilitator Superfamily
PI861_16515	COG1349	DNA-binding transcription factor activity
PI861_16525	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
PI861_16530	COG0584	glycerophosphoryl diester phosphodiesterase
PI861_16535	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
PI861_16540	COG0287	Prephenate dehydrogenase
PI861_16540	COG1605	Chorismate mutase
PI861_16550	COG3085	chromosome segregation
PI861_16555	COG4574	serine-type endopeptidase inhibitor activity
PI861_16575	COG1770	oligopeptidase
PI861_16580	COG4771	TonB-dependent receptor
PI861_16585	COG3083	sulfuric ester hydrolase activity
PI861_16590	COG3082	Protein of unknown function (DUF1414)
PI861_16595	COG3081	Nucleoid-associated protein
PI861_16600	COG2182	Extracellular solute-binding protein
PI861_16605	COG1175	transmembrane transport
PI861_16610	COG3833	ABC-type maltose transport systems, permease component
PI861_16615	COG3842	ATPase activity
PI861_16630	COG0628	permease
PI861_16635	COG0425	Belongs to the sulfur carrier protein TusA family
PI861_16640	COG4783	chaperone-mediated protein folding
PI861_16650	COG1393	Belongs to the ArsC family
PI861_16660	COG3124	Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP
PI861_16665	COG2431	L-lysine efflux transmembrane transporter activity
PI861_16700	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
PI861_16715	COG2373	Large extracellular alpha-helical protein
PI861_16720	COG4953	penicillin-binding protein 1C
PI861_16730	COG0301	tRNA thio-modification
PI861_16730	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
PI861_16745	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
PI861_16750	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
PI861_16785	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
PI861_16795	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
PI861_16815	COG0483	inositol monophosphate 1-phosphatase activity
PI861_16825	COG0625	glutathione transferase activity
PI861_16840	COG0601	transmembrane transport
PI861_16845	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
PI861_16850	COG0444	Belongs to the ABC transporter superfamily
PI861_16855	COG2814	Major facilitator Superfamily
PI861_16860	COG0583	DNA-binding transcription factor activity
PI861_16865	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
PI861_16890	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
PI861_16895	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
PI861_16900	COG0404	The glycine cleavage system catalyzes the degradation of glycine
PI861_16905	COG0509	glycine decarboxylation via glycine cleavage system
PI861_16910	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
PI861_16910	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
PI861_16925	COG3634	alkyl hydroperoxide reductase activity
PI861_16935	COG0517	IMP dehydrogenase activity
PI861_16940	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
PI861_16945	COG0343	queuine tRNA-ribosyltransferase activity
PI861_16950	COG1862	Preprotein translocase
PI861_16955	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
PI861_16960	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
PI861_16965	COG2897	thiosulfate sulfurtransferase activity
PI861_16975	COG0826	peptidase U32
PI861_16980	COG0826	peptidase U32
PI861_16985	COG3154	lipid carrier protein
PI861_17005	COG1104	cysteine desulfurase activity
PI861_17010	COG0822	iron-sulfur transferase activity
PI861_17020	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
PI861_17025	COG0443	Heat shock 70 kDa protein
PI861_17030	COG0633	Ferredoxin
PI861_17040	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
PI861_17045	COG0105	UTP biosynthetic process
PI861_17050	COG0820	rRNA (adenine-C2-)-methyltransferase activity
PI861_17060	COG1426	Protein conserved in bacteria
PI861_17065	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
PI861_17070	COG0124	histidyl-tRNA synthetase
PI861_17075	COG2976	Protein conserved in bacteria
PI861_17080	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
PI861_17085	COG1160	GTP binding
PI861_17090	COG1645	bacterial-type flagellum-dependent swarming motility
PI861_17095	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
PI861_17100	COG0047	phosphoribosylformylglycinamidine synthase activity
PI861_17100	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
PI861_17110	COG2354	Protein conserved in bacteria
PI861_17125	COG3150	esterase
PI861_17130	COG1252	NADH dehydrogenase
PI861_17135	COG0393	Putative heavy-metal-binding
PI861_17145	COG1619	proteins homologs of microcin C7 resistance protein MccF
PI861_17150	COG1368	sulfuric ester hydrolase activity
PI861_17160	COG0527	aspartate kinase activity
PI861_17165	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
PI861_17165	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
PI861_17170	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
PI861_17210	COG1285	pathogenesis
PI861_17225	COG0577	efflux transmembrane transporter activity
PI861_17270	COG0672	)-iron permease
PI861_17310	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
PI861_17315	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
PI861_17315	COG0574	Belongs to the PEP-utilizing enzyme family
PI861_17355	COG1464	Belongs to the NlpA lipoprotein family
PI861_17360	COG0671	phosphoesterase, PA-phosphatase related
PI861_17365	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
PI861_17370	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
PI861_17380	COG0101	tRNA pseudouridine synthase activity
PI861_17385	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
PI861_17390	COG0285	dihydrofolate synthase activity
PI861_17395	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
PI861_17400	COG2920	part of a sulfur-relay system
PI861_17405	COG1289	transmembrane transporter activity
PI861_17410	COG0670	Belongs to the BI1 family
PI861_17420	COG0840	transmembrane signaling receptor activity
PI861_17430	COG0564	pseudouridine synthase activity
PI861_17455	COG0625	glutathione transferase activity
PI861_17460	COG0625	glutathione transferase activity
PI861_17480	COG0367	asparagine synthase
PI861_17490	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
PI861_17490	COG4651	solute:proton antiporter activity
PI861_17495	COG0647	UMP catabolic process
PI861_17505	COG1902	pentaerythritol trinitrate reductase activity
PI861_17510	COG1253	flavin adenine dinucleotide binding
PI861_17520	COG0247	lactate metabolic process
PI861_17520	COG0277	FAD linked oxidase domain protein
PI861_17530	COG2050	protein possibly involved in aromatic compounds catabolism
PI861_17535	COG0513	Belongs to the DEAD box helicase family
PI861_17545	COG3300	MHYT domain
PI861_17545	COG5001	Diguanylate cyclase
PI861_17550	COG2056	Na+-H+ antiporter family
PI861_17555	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
PI861_17570	COG0346	lactoylglutathione lyase activity
PI861_17575	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
PI861_17580	COG4660	Part of a membrane complex involved in electron transport
PI861_17585	COG4659	FMN binding
PI861_17590	COG4658	electron transport chain
PI861_17600	COG2878	Part of a membrane complex involved in electron transport
PI861_17605	COG4657	Part of a membrane complex involved in electron transport
PI861_17610	COG0697	spore germination
PI861_17655	COG0659	secondary active sulfate transmembrane transporter activity
PI861_17725	COG3829	transcription factor binding
PI861_17785	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
PI861_17790	COG1278	Cold shock
PI861_17795	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
PI861_17800	COG0542	response to heat
PI861_17805	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
PI861_17810	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
PI861_17815	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
PI861_17820	COG3134	Outer membrane lipoprotein
PI861_17825	COG3706	GGDEF domain
PI861_17830	COG0492	ferredoxin-NADP+ reductase activity
PI861_17845	COG0531	amino acid
PI861_17845	COG1674	ftsk spoiiie
PI861_17850	COG0531	amino acid
PI861_17850	COG1674	ftsk spoiiie
PI861_17855	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
PI861_17860	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
PI861_17865	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
PI861_17870	COG1286	toxin biosynthetic process
PI861_17875	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
PI861_17885	COG4172	Belongs to the ABC transporter superfamily
PI861_17890	COG4172	Belongs to the ABC transporter superfamily
PI861_17895	COG4171	peptide transport system, permease
PI861_17900	COG4168	peptide transport system, permease
PI861_17910	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
PI861_17915	COG1842	Phage shock protein A
PI861_17930	COG3106	COG3106 Predicted ATPase
PI861_17935	COG3768	UPF0283 membrane protein
PI861_17945	COG2154	pterin-4-alpha-carbinolamine dehydratase
PI861_17960	COG2199	diguanylate cyclase activity
PI861_17970	COG0861	Integral membrane protein TerC family
PI861_17985	COG1022	Amp-dependent synthetase and ligase
PI861_17990	COG0295	cytidine deaminase activity
PI861_17995	COG1346	cytolysis
PI861_18000	COG1380	Effector of murein hydrolase LrgA
PI861_18015	COG2925	Exonuclease
PI861_18030	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
PI861_18035	COG0436	Aminotransferase
PI861_18045	COG0583	DNA-binding transcription factor activity
PI861_18050	COG2160	L-arabinose isomerase activity
PI861_18060	COG1069	ribulokinase activity
PI861_18065	COG1879	ABC-type sugar transport system periplasmic component
PI861_18070	COG1129	ABC transporter
PI861_18075	COG1172	Belongs to the binding-protein-dependent transport system permease family
PI861_18085	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
PI861_18090	COG1085	galactose-1-phosphate uridylyltransferase
PI861_18095	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
PI861_18100	COG1609	Transcriptional regulator
PI861_18105	COG4580	involved in the transport of maltose and maltodextrins
PI861_18145	COG2182	Extracellular solute-binding protein
PI861_18150	COG1175	transmembrane transport
PI861_18155	COG3833	ABC-type maltose transport systems, permease component
PI861_18160	COG3867	Arabinogalactan endo-beta-1,4-galactanase
PI861_18165	COG1874	Beta-galactosidase
PI861_18175	COG0469	pyruvate kinase activity
PI861_18180	COG0257	Belongs to the bacterial ribosomal protein bL36 family
PI861_18185	COG0254	rRNA binding
PI861_18200	COG1451	nucleotide metabolic process
PI861_18215	COG3069	C4-dicarboxylate transmembrane transporter activity
PI861_18225	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
PI861_18225	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
PI861_18230	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
PI861_18255	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
PI861_18260	COG1053	succinate dehydrogenase
PI861_18270	COG0567	Dehydrogenase, E1 component
PI861_18275	COG0508	dehydrogenase complex catalyzes the overall conversion of
PI861_18280	COG0045	succinate-CoA ligase (ADP-forming) activity
PI861_18285	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
PI861_18290	COG2983	Belongs to the UPF0260 family
PI861_18295	COG1882	Formate acetyltransferase
PI861_18300	COG2116	formate transmembrane transporter activity
PI861_18305	COG1944	ATP diphosphatase activity
PI861_18310	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
PI861_18315	COG0612	Peptidase, M16
PI861_18330	COG2910	NAD(P)H-binding
PI861_18335	COG0583	DNA-binding transcription factor activity
PI861_18345	COG2207	Transcriptional regulator
PI861_18345	COG3708	Transcriptional regulator
PI861_18350	COG4774	siderophore transport
PI861_18360	COG0583	DNA-binding transcription factor activity
PI861_18365	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
PI861_18390	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
PI861_18395	COG3046	protein related to deoxyribodipyrimidine photolyase
PI861_18405	COG3033	Beta-eliminating lyase
PI861_18420	COG3088	subunit of a heme lyase
PI861_18420	COG4235	cytochrome complex assembly
PI861_18435	COG3301	Polysulphide reductase, NrfD
PI861_18440	COG0437	4 iron, 4 sulfur cluster binding
PI861_18445	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
PI861_18455	COG0247	lactate metabolic process
PI861_18460	COG3075	Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses fumarate or nitrate as electron acceptor
PI861_18465	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
PI861_18470	COG3012	SEC-C Motif Domain Protein
PI861_18475	COG0840	transmembrane signaling receptor activity
PI861_18480	COG1940	carbohydrate kinase activity
PI861_18480	COG1846	Transcriptional regulator
PI861_18485	COG3290	protein histidine kinase activity
PI861_18490	COG4565	transcriptional regulatory protein
PI861_18510	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
PI861_18515	COG0569	domain protein
PI861_18515	COG2985	domain, Protein
PI861_18525	COG0556	nucleotide-excision repair
PI861_18535	COG0586	Pfam SNARE associated Golgi protein
PI861_18540	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
PI861_18545	COG3067	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
PI861_18550	COG2186	Transcriptional regulator
PI861_18555	COG2719	SpoVR family
PI861_18565	COG2766	serine protein kinase
PI861_18570	COG0514	ATP-dependent DNA helicase (RecQ)
PI861_18575	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
PI861_18580	COG0814	amino acid
PI861_18615	COG0058	SHG alpha-glucan phosphorylase activity
PI861_18620	COG0471	metal ion transport
PI861_18625	COG3118	belongs to the thioredoxin family
PI861_18640	COG1132	(ABC) transporter
PI861_18650	COG2501	S4 domain
PI861_18660	COG3243	poly(R)-hydroxyalkanoic acid synthase
PI861_18680	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
PI861_18685	COG2329	Antibiotic biosynthesis monooxygenase
PI861_18725	COG1742	UPF0060 membrane protein
PI861_18740	COG0513	Belongs to the DEAD box helicase family
PI861_18745	COG0386	Belongs to the glutathione peroxidase family
PI861_18755	COG1181	Belongs to the D-alanine--D-alanine ligase family
PI861_18765	COG3148	PFAM DTW domain containing protein
PI861_18770	COG0730	response to heat
PI861_18775	COG0583	DNA-binding transcription factor activity
PI861_18790	COG3593	DNA synthesis involved in DNA repair
PI861_18845	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
PI861_18850	COG1011	Hydrolase
PI861_18900	COG0205	6-phosphofructokinase activity
PI861_18910	COG1434	Gram-negative-bacterium-type cell wall biogenesis
PI861_18915	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
PI861_18925	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
PI861_18930	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
PI861_18935	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
PI861_18995	COG4681	YaeQ
PI861_19015	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
PI861_19035	COG3134	Outer membrane lipoprotein
PI861_19045	COG1288	antiporter activity
PI861_19055	COG1028	Short-chain dehydrogenase reductase Sdr
PI861_19060	COG0583	DNA-binding transcription factor activity
PI861_19065	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
PI861_19070	COG0673	inositol 2-dehydrogenase activity
PI861_19075	COG0583	DNA-binding transcription factor activity
PI861_19085	COG1560	Kdo2-lipid A biosynthetic process
PI861_19090	COG1560	Kdo2-lipid A biosynthetic process
PI861_19105	COG2199	diguanylate cyclase activity
PI861_19105	COG2203	Gaf domain
PI861_19115	COG0417	DNA replication proofreading
PI861_19140	COG0534	Mate efflux family protein
PI861_19150	COG0307	riboflavin synthase, alpha
PI861_19160	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
PI861_19165	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
PI861_19170	COG0697	spore germination
PI861_19175	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
PI861_19220	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
PI861_19225	COG3099	Belongs to the UPF0263 family
PI861_19230	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
PI861_19235	COG2894	cell division
PI861_19240	COG0850	regulation of cytokinetic process
PI861_19245	COG3100	YcgL domain-containing protein
PI861_19250	COG2951	lytic endotransglycosylase activity
PI861_19255	COG1760	l-serine dehydratase
PI861_19260	COG1760	l-serine dehydratase
PI861_19265	COG3123	guanosine phosphorylase activity
PI861_19285	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
PI861_19290	COG2067	long-chain fatty acid transport protein
PI861_19295	COG2067	long-chain fatty acid transport protein
PI861_19335	COG0714	Associated with various cellular activities
PI861_19340	COG0183	Belongs to the thiolase family
PI861_19345	COG1024	Enoyl-CoA hydratase
PI861_19345	COG1250	3-hydroxyacyl-CoA dehydrogenase
PI861_19350	COG2824	Alkylphosphonate utilization operon protein PhnA
PI861_19370	COG1879	ABC-type sugar transport system periplasmic component
PI861_19375	COG1129	ABC transporter
PI861_19380	COG1172	Belongs to the binding-protein-dependent transport system permease family
PI861_19385	COG1172	Belongs to the binding-protein-dependent transport system permease family
PI861_19390	COG5001	Diguanylate cyclase
PI861_19390	COG4251	negative regulation of phosphorylation
PI861_19390	COG2203	Gaf domain
PI861_19390	COG3706	GGDEF domain
PI861_19395	COG2823	Periplasmic or secreted lipoprotein
PI861_19450	COG2378	regulation of single-species biofilm formation
PI861_19460	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
PI861_19460	COG0140	phosphoribosyl-ATP diphosphatase activity
PI861_19465	COG0107	imidazoleglycerol-phosphate synthase activity
PI861_19470	COG0784	Response regulator, receiver
PI861_19470	COG2198	Histidine kinase
PI861_19470	COG2205	protein histidine kinase activity
PI861_19475	COG2199	diguanylate cyclase activity
PI861_19480	COG3437	response regulator, receiver
PI861_19485	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
PI861_19490	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
PI861_19495	COG0131	Imidazoleglycerol-phosphate dehydratase
PI861_19495	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
PI861_19500	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
PI861_19505	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
PI861_19510	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
PI861_19520	COG1199	ATP-dependent helicase activity
PI861_19525	COG1214	PFAM Peptidase M22, glycoprotease
PI861_19535	COG2267	carboxylic ester hydrolase activity
PI861_19540	COG0318	PFAM AMP-dependent synthetase and ligase
PI861_19560	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
PI861_19565	COG2832	Protein of unknown function (DUF454)
PI861_19570	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
PI861_19575	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
PI861_19580	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
PI861_19585	COG3314	Sporulation integral membrane protein YlbJ
PI861_19590	COG2197	response regulator
PI861_19595	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
PI861_19595	COG0617	tRNA 3'-terminal CCA addition
PI861_19595	COG0517	IMP dehydrogenase activity
PI861_19600	COG1643	Atp-dependent helicase
PI861_19610	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
PI861_19615	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
PI861_19620	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
PI861_19625	COG0709	Synthesizes selenophosphate from selenide and ATP
PI861_19640	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
PI861_19650	COG1254	Belongs to the acylphosphatase family
PI861_19655	COG0625	glutathione transferase activity
PI861_19665	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
PI861_19665	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
PI861_19670	COG0489	protein tyrosine kinase activity
PI861_19675	COG0572	uridine kinase
PI861_19680	COG0717	Belongs to the dCTP deaminase family
PI861_19685	COG0306	phosphate transporter
PI861_19690	COG1530	ribonuclease E activity
PI861_19700	COG0546	phosphoglycolate phosphatase activity
PI861_19710	COG1399	metal-binding, possibly nucleic acid-binding protein
PI861_19715	COG0333	Belongs to the bacterial ribosomal protein bL32 family
PI861_19720	COG0416	fatty acid biosynthetic process
PI861_19725	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
PI861_19735	COG1028	Short-chain dehydrogenase reductase Sdr
PI861_19740	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
PI861_19745	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
PI861_19750	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
PI861_19755	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
PI861_19760	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
PI861_19765	COG0470	DNA polymerase III
PI861_19770	COG0084	hydrolase, TatD family'
PI861_19785	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
PI861_19785	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
PI861_19795	COG2995	paraquat-inducible protein a
PI861_19805	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
PI861_19855	COG4221	oxidoreductase activity
PI861_19925	COG4128	Pfam Zonular occludens toxin
PI861_19930	COG4584	PFAM Integrase catalytic
PI861_19935	COG1484	DNA-dependent DNA replication
PI861_20000	COG4128	Pfam Zonular occludens toxin
PI861_20015	COG1067	ATP-dependent peptidase activity
PI861_20020	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
PI861_20035	COG0488	(ABC) transporter
PI861_20045	COG0116	Belongs to the methyltransferase superfamily
PI861_20045	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
PI861_20055	COG0167	dihydroorotate dehydrogenase activity
PI861_20060	COG2902	Dehydrogenase
PI861_20070	COG0308	aminopeptidase N
PI861_20080	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
PI861_20085	COG1956	GAF domain-containing protein
PI861_20095	COG3278	Belongs to the heme-copper respiratory oxidase family
PI861_20110	COG2010	Cytochrome c
PI861_20120	COG2217	Heavy metal translocating P-type atpase
PI861_20135	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
PI861_20140	COG0589	response to stress
PI861_20145	COG0037	tRNA processing
PI861_20160	COG0625	glutathione transferase activity
PI861_20165	COG1869	D-ribose catabolic process
PI861_20175	COG1172	Belongs to the binding-protein-dependent transport system permease family
PI861_20180	COG1879	ABC-type sugar transport system periplasmic component
PI861_20185	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
PI861_20190	COG1609	Transcriptional regulator
PI861_20195	COG2199	diguanylate cyclase activity
PI861_20225	COG0776	regulation of translation
PI861_20230	COG0072	phenylalanine-tRNA ligase activity
PI861_20230	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
PI861_20235	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
PI861_20240	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
PI861_20245	COG0291	Belongs to the bacterial ribosomal protein bL35 family
PI861_20250	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
PI861_20255	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
PI861_20280	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
PI861_20290	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
PI861_20295	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
PI861_20300	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
PI861_20305	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
PI861_20310	COG3313	Fe-S protein
PI861_20315	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
PI861_20315	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
PI861_20315	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
PI861_20320	COG1105	Belongs to the carbohydrate kinase PfkB family
PI861_20325	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
PI861_20325	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
PI861_20330	COG1609	Transcriptional regulator
PI861_20335	COG0814	amino acid
PI861_20345	COG5654	RES domain protein
PI861_20350	COG0513	Belongs to the DEAD box helicase family
PI861_20360	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
PI861_20365	COG2890	protein-(glutamine-N5) methyltransferase activity
PI861_20370	COG2840	Smr protein MutS2
PI861_20375	COG3706	GGDEF domain
PI861_20430	COG0730	response to heat
PI861_20440	COG1028	Short-chain dehydrogenase reductase Sdr
PI861_20450	COG1024	Enoyl-CoA hydratase
PI861_20455	COG1024	Enoyl-CoA hydratase
PI861_20460	COG1960	acyl-CoA dehydrogenase activity
PI861_20470	COG1960	acyl-CoA dehydrogenase activity
PI861_20475	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
PI861_20480	COG1024	Enoyl-CoA hydratase
PI861_20510	COG1584	GPR1 FUN34 yaaH family protein
PI861_20520	COG0456	acetyltransferase
PI861_20525	COG1115	amino acid carrier protein
PI861_20530	COG1250	3-hydroxyacyl-CoA dehydrogenase
PI861_20530	COG1024	Enoyl-CoA hydratase
PI861_20545	COG3162	membrane
PI861_20550	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
PI861_20555	COG0488	(ABC) transporter
PI861_20560	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
PI861_20565	COG0776	regulation of translation
PI861_20570	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
PI861_20575	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
PI861_20580	COG0740	serine-type endopeptidase activity
PI861_20585	COG0544	peptidyl-prolyl cis-trans isomerase activity
PI861_20595	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
PI861_20600	COG4591	ABC-type transport system involved in lipoprotein release permease component
PI861_20605	COG1136	(ABC) transporter
PI861_20610	COG4591	ABC-type transport system involved in lipoprotein release permease component
PI861_20620	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
PI861_20625	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
PI861_20630	COG4166	transmembrane transport
PI861_20635	COG0697	spore germination
PI861_20645	COG2062	phosphohistidine phosphatase, SixA
PI861_20650	COG1025	Belongs to the peptidase M16 family
PI861_20685	COG0518	GMP synthase (glutamine-hydrolyzing) activity
PI861_20685	COG0519	Catalyzes the synthesis of GMP from XMP
PI861_20690	COG0516	GMP reductase activity
PI861_20690	COG0517	IMP dehydrogenase activity
PI861_20710	COG3038	cytochrome b561
PI861_20715	COG1570	exodeoxyribonuclease VII activity
PI861_20730	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
PI861_20735	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
PI861_20740	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
PI861_20780	COG4771	TonB-dependent receptor
PI861_20785	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
PI861_20790	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
PI861_20795	COG1120	ATPase activity
PI861_20800	COG2977	Belongs to the P-Pant transferase superfamily
PI861_20805	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
PI861_20810	COG1028	Short-chain dehydrogenase reductase Sdr
PI861_20810	COG3321	synthase
PI861_20810	COG0300	oxidoreductase activity
PI861_20810	COG0318	PFAM AMP-dependent synthetase and ligase
PI861_20810	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
PI861_20820	COG1028	Short-chain dehydrogenase reductase Sdr
PI861_20825	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
PI861_20830	COG1535	isochorismatase
PI861_20830	COG3433	isochorismatase activity
PI861_20835	COG1021	2,3-dihydroxybenzoate-AMP ligase
PI861_20855	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
PI861_20860	COG5001	Diguanylate cyclase
PI861_20860	COG3300	MHYT domain
PI861_20875	COG0840	transmembrane signaling receptor activity
PI861_20880	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
PI861_20885	COG3788	relative of glutathione S-transferase, MAPEG superfamily
PI861_20890	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
PI861_20895	COG0563	adenylate kinase activity
PI861_20900	COG0326	Molecular chaperone. Has ATPase activity
PI861_20905	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
PI861_20930	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
PI861_20950	COG3158	transport of potassium into the cell
PI861_20955	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
PI861_20960	COG0651	ATP synthesis coupled electron transport
PI861_20965	COG0650	Formate hydrogenlyase subunit 4
PI861_20970	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
PI861_20970	COG3261	NADH dehydrogenase
PI861_20975	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
PI861_20980	COG3260	NADH ubiquinone oxidoreductase 20
PI861_20990	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
PI861_21000	COG1921	L-seryl-tRNASec selenium transferase activity
PI861_21010	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
PI861_21015	COG0298	carbon dioxide binding
PI861_21025	COG0309	Hydrogenase expression formation protein (HypE)
PI861_21030	COG0375	protein maturation
PI861_21035	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
PI861_21050	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
PI861_21055	COG0601	transmembrane transport
PI861_21065	COG1773	rubredoxin
PI861_21070	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
PI861_21075	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
PI861_21080	COG5557	Pfam Polysulphide reductase, NrfD
PI861_21085	COG0437	4 iron, 4 sulfur cluster binding
PI861_21090	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
PI861_21095	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
PI861_21120	COG1435	thymidine kinase activity
PI861_21125	COG1757	Na H antiporter
PI861_21135	COG2916	Histone family protein nucleoid-structuring protein H-NS
PI861_21140	COG2096	Adenosyltransferase
PI861_21145	COG3530	Putative quorum-sensing-regulated virulence factor
PI861_21150	COG0602	queuosine metabolic process
PI861_21155	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
PI861_21170	COG0284	orotidine-5'-phosphate decarboxylase activity
PI861_21175	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
PI861_21185	COG0776	regulation of translation
PI861_21190	COG0539	negative regulation of cytoplasmic translation
PI861_21195	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
PI861_21200	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
PI861_21210	COG0583	DNA-binding transcription factor activity
PI861_21215	COG2814	Major facilitator Superfamily
PI861_21250	COG0583	DNA-binding transcription factor activity
PI861_21255	COG3437	response regulator, receiver
PI861_21280	COG4989	oxidoreductase activity
PI861_21285	COG0724	RNA recognition motif
PI861_21295	COG1126	abc transporter atp-binding protein
PI861_21300	COG0765	amino acid transport
PI861_21305	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
PI861_21310	COG4597	amino acid ABC transporter
PI861_21325	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
PI861_21340	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
PI861_21345	COG1360	Flagellar Motor Protein
PI861_21350	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
PI861_21355	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
PI861_21360	COG0649	NAD binding
PI861_21360	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
PI861_21375	COG1034	ATP synthesis coupled electron transport
PI861_21380	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
PI861_21385	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
PI861_21390	COG0839	Belongs to the complex I subunit 6 family
PI861_21395	COG0713	ATP synthesis coupled electron transport
PI861_21405	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
PI861_21410	COG1007	ATP synthesis coupled electron transport
PI861_21430	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
PI861_21435	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
PI861_21470	COG0537	adenosine 5'-monophosphoramidase activity
PI861_21485	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
PI861_21500	COG1301	dicarboxylic acid transport
PI861_21510	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
PI861_21515	COG0861	Integral membrane protein TerC family
PI861_21530	COG0444	Belongs to the ABC transporter superfamily
PI861_21535	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
PI861_21540	COG0601	transmembrane transport
PI861_21550	COG2095	MarC family integral membrane protein
PI861_21560	COG1012	belongs to the aldehyde dehydrogenase family
PI861_21560	COG1454	alcohol dehydrogenase
PI861_21570	COG3275	phosphorelay sensor kinase activity
PI861_21575	COG3279	Response regulator of the LytR AlgR family
PI861_21580	COG1966	Carbon starvation protein
PI861_21590	COG1566	PFAM secretion protein HlyD family protein
PI861_21595	COG1061	Type III restriction enzyme res subunit
PI861_21600	COG2027	D-alanyl-D-alanine carboxypeptidase
PI861_21605	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
PI861_21615	COG0436	Aminotransferase
PI861_21620	COG1288	antiporter activity
PI861_21625	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
PI861_21710	COG1242	4 iron, 4 sulfur cluster binding
PI861_21715	COG0070	glutamate synthase
PI861_21715	COG0069	glutamate synthase activity
PI861_21715	COG0067	glutamate synthase
PI861_21720	COG0493	'glutamate synthase
PI861_21735	COG0789	Transcriptional regulator
PI861_21760	COG0513	Belongs to the DEAD box helicase family
PI861_21765	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
PI861_21805	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
PI861_21810	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
PI861_21815	COG0505	Belongs to the CarA family
PI861_21820	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
PI861_21840	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
PI861_21845	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
PI861_21850	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
PI861_21855	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
PI861_21860	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
PI861_21865	COG4138	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system
PI861_21875	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
PI861_21875	COG2205	protein histidine kinase activity
PI861_21920	COG2119	membrane
PI861_21980	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
PI861_21990	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
PI861_22020	COG4974	Belongs to the 'phage' integrase family
PI861_22030	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
PI861_22100	COG4695	Portal protein
PI861_22245	COG4737	Cytotoxic translational repressor of toxin-antitoxin stability system
PI861_22275	COG2026	Addiction module toxin, RelE StbE family
PI861_22280	COG3077	Addiction module antitoxin, RelB DinJ family
PI861_22370	COG3328	transposase activity
PI861_22465	COG4792	protein secretion
PI861_22470	COG4791	protein targeting
PI861_22475	COG4794	Type iii secretion
PI861_22480	COG4790	Type iii secretion
PI861_22550	COG0457	Tetratricopeptide repeat
PI861_22640	COG1317	bacterial-type flagellum organization
PI861_22670	COG3328	transposase activity
PI861_22800	COG1192	Involved in chromosome partitioning
PI861_22815	COG2916	Histone family protein nucleoid-structuring protein H-NS
PI861_22840	COG4584	PFAM Integrase catalytic
PI861_22845	COG1484	DNA-dependent DNA replication
PI861_22870	COG0393	Putative heavy-metal-binding
PI861_22900	COG3328	transposase activity
PI861_22910	COG1192	Involved in chromosome partitioning
PI861_22920	COG2916	Histone family protein nucleoid-structuring protein H-NS
PI861_22950	COG1192	Involved in chromosome partitioning
PI861_22955	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
PI861_22965	COG2194	sulfuric ester hydrolase activity
PI861_22970	COG2194	sulfuric ester hydrolase activity
PI861_22995	COG1484	DNA-dependent DNA replication
PI861_23000	COG4584	PFAM Integrase catalytic
PI861_23040	COG2003	Belongs to the UPF0758 family
PI861_23105	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
PI861_23305	COG4584	PFAM Integrase catalytic
PI861_23310	COG1484	DNA-dependent DNA replication
PI861_23315	COG3328	transposase activity
PI861_23350	COG4792	protein secretion
PI861_23355	COG4791	protein targeting
PI861_23360	COG4794	Type iii secretion
PI861_23365	COG4790	Type iii secretion