locus-tag	class	description
GO992_00015	COG3162	membrane
GO992_00040	COG1250	3-hydroxyacyl-CoA dehydrogenase
GO992_00040	COG1024	Enoyl-CoA hydratase
GO992_00045	COG1115	amino acid carrier protein
GO992_00050	COG0456	acetyltransferase
GO992_00060	COG1584	GPR1 FUN34 yaaH family protein
GO992_00080	COG5433	transposase activity
GO992_00100	COG1757	Na H antiporter
GO992_00105	COG1435	thymidine kinase activity
GO992_00125	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
GO992_00130	COG5433	transposase activity
GO992_00145	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
GO992_00150	COG0437	4 iron, 4 sulfur cluster binding
GO992_00155	COG5557	Pfam Polysulphide reductase, NrfD
GO992_00160	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
GO992_00165	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
GO992_00170	COG1773	rubredoxin
GO992_00180	COG0601	transmembrane transport
GO992_00185	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GO992_00200	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
GO992_00205	COG0375	protein maturation
GO992_00210	COG0309	Hydrogenase expression formation protein (HypE)
GO992_00220	COG0298	carbon dioxide binding
GO992_00225	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
GO992_00235	COG1921	L-seryl-tRNASec selenium transferase activity
GO992_00245	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
GO992_00255	COG3260	NADH ubiquinone oxidoreductase 20
GO992_00260	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
GO992_00265	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
GO992_00265	COG3261	NADH dehydrogenase
GO992_00270	COG0650	Formate hydrogenlyase subunit 4
GO992_00275	COG0651	ATP synthesis coupled electron transport
GO992_00280	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
GO992_00285	COG3158	transport of potassium into the cell
GO992_00310	COG3328	transposase activity
GO992_00360	COG1846	Transcriptional regulator
GO992_00360	COG1940	carbohydrate kinase activity
GO992_00365	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
GO992_00370	COG0363	glucosamine-6-phosphate deaminase activity
GO992_00385	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
GO992_00390	COG0735	belongs to the Fur family
GO992_00400	COG0716	FMN binding
GO992_00415	COG0596	Alpha beta hydrolase
GO992_00420	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
GO992_00425	COG0033	Phosphoglucomutase
GO992_00435	COG1846	Transcriptional regulator
GO992_00440	COG2951	lytic endotransglycosylase activity
GO992_00445	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
GO992_00450	COG4136	ATPase activity
GO992_00460	COG4134	Bacterial extracellular solute-binding protein
GO992_00470	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
GO992_00480	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
GO992_00485	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
GO992_00495	COG0729	surface antigen
GO992_00500	COG2911	Protein conserved in bacteria
GO992_00515	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
GO992_00540	COG1607	acyl-coa hydrolase
GO992_00550	COG3021	interspecies interaction between organisms
GO992_00555	COG1388	LysM domain
GO992_00555	COG0741	lytic transglycosylase activity
GO992_00560	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GO992_00565	COG2226	methyltransferase
GO992_00570	COG0328	RNA-DNA hybrid ribonuclease activity
GO992_00575	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
GO992_00600	COG1960	acyl-CoA dehydrogenase activity
GO992_00605	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
GO992_00610	COG0121	glutamine amidotransferase
GO992_00640	COG2197	response regulator
GO992_00645	COG3850	Histidine kinase
GO992_00650	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
GO992_00655	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
GO992_00665	COG0243	molybdopterin cofactor binding
GO992_00670	COG0437	4 iron, 4 sulfur cluster binding
GO992_00675	COG0348	domain, Protein
GO992_00685	COG3005	denitrification pathway
GO992_00695	COG0315	cyclic pyranopterin monophosphate synthase activity
GO992_00700	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
GO992_00705	COG0314	molybdopterin synthase activity
GO992_00720	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
GO992_00725	COG0596	Alpha beta hydrolase
GO992_00750	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
GO992_00760	COG0302	gtp cyclohydrolase
GO992_00765	COG0840	transmembrane signaling receptor activity
GO992_00770	COG2759	Belongs to the formate--tetrahydrofolate ligase family
GO992_00780	COG0583	DNA-binding transcription factor activity
GO992_00785	COG2353	YceI-like domain
GO992_00820	COG2195	Cleaves the N-terminal amino acid of tripeptides
GO992_00830	COG1166	arginine decarboxylase activity
GO992_00850	COG2814	Major facilitator Superfamily
GO992_00855	COG0656	L-ascorbic acid biosynthetic process
GO992_00860	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
GO992_00885	COG0583	DNA-binding transcription factor activity
GO992_00890	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
GO992_00895	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
GO992_00900	COG2271	Major facilitator Superfamily
GO992_00905	COG1349	DNA-binding transcription factor activity
GO992_00915	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
GO992_00920	COG0584	glycerophosphoryl diester phosphodiesterase
GO992_00925	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
GO992_00930	COG0287	Prephenate dehydrogenase
GO992_00930	COG1605	Chorismate mutase
GO992_00935	COG0583	DNA-binding transcription factor activity
GO992_00940	COG3085	chromosome segregation
GO992_00945	COG4574	serine-type endopeptidase inhibitor activity
GO992_00965	COG1770	oligopeptidase
GO992_00970	COG4771	TonB-dependent receptor
GO992_00975	COG3083	sulfuric ester hydrolase activity
GO992_00980	COG3082	Protein of unknown function (DUF1414)
GO992_00985	COG3081	Nucleoid-associated protein
GO992_00995	COG2182	Extracellular solute-binding protein
GO992_01000	COG1175	transmembrane transport
GO992_01010	COG3842	ATPase activity
GO992_01025	COG0628	permease
GO992_01030	COG0425	Belongs to the sulfur carrier protein TusA family
GO992_01035	COG4783	chaperone-mediated protein folding
GO992_01045	COG1393	Belongs to the ArsC family
GO992_01055	COG3124	Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP
GO992_01060	COG2431	L-lysine efflux transmembrane transporter activity
GO992_01075	COG4215	(ABC) transporter
GO992_01095	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
GO992_01105	COG0446	pyridine nucleotide-disulphide oxidoreductase
GO992_01110	COG2373	Large extracellular alpha-helical protein
GO992_01115	COG4953	penicillin-binding protein 1C
GO992_01125	COG0301	tRNA thio-modification
GO992_01125	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
GO992_01155	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
GO992_01170	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
GO992_01180	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
GO992_01200	COG0483	inositol monophosphate 1-phosphatase activity
GO992_01220	COG0625	glutathione transferase activity
GO992_01230	COG0601	transmembrane transport
GO992_01235	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GO992_01240	COG0444	Belongs to the ABC transporter superfamily
GO992_01245	COG2814	Major facilitator Superfamily
GO992_01250	COG0583	DNA-binding transcription factor activity
GO992_01255	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
GO992_01260	COG0243	molybdopterin cofactor binding
GO992_01280	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
GO992_01285	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
GO992_01290	COG0404	The glycine cleavage system catalyzes the degradation of glycine
GO992_01295	COG0509	glycine decarboxylation via glycine cleavage system
GO992_01300	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
GO992_01300	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
GO992_01315	COG3634	alkyl hydroperoxide reductase activity
GO992_01320	COG0450	alkyl hydroperoxide reductase
GO992_01325	COG0517	IMP dehydrogenase activity
GO992_01330	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
GO992_01335	COG0343	queuine tRNA-ribosyltransferase activity
GO992_01340	COG1862	Preprotein translocase
GO992_01345	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
GO992_01350	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
GO992_01355	COG2897	thiosulfate sulfurtransferase activity
GO992_01390	COG1959	2 iron, 2 sulfur cluster binding
GO992_01395	COG1104	cysteine desulfurase activity
GO992_01400	COG0822	iron-sulfur transferase activity
GO992_01410	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
GO992_01415	COG0443	Heat shock 70 kDa protein
GO992_01420	COG0633	Ferredoxin
GO992_01430	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
GO992_01435	COG0105	UTP biosynthetic process
GO992_01440	COG0820	rRNA (adenine-C2-)-methyltransferase activity
GO992_01450	COG1426	Protein conserved in bacteria
GO992_01455	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
GO992_01460	COG0124	histidyl-tRNA synthetase
GO992_01465	COG2976	Protein conserved in bacteria
GO992_01470	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
GO992_01475	COG1160	GTP binding
GO992_01480	COG1645	bacterial-type flagellum-dependent swarming motility
GO992_01485	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
GO992_01490	COG0047	phosphoribosylformylglycinamidine synthase activity
GO992_01490	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
GO992_01500	COG2354	Protein conserved in bacteria
GO992_01520	COG5433	transposase activity
GO992_01550	COG1024	Enoyl-CoA hydratase
GO992_01555	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
GO992_01560	COG1960	acyl-CoA dehydrogenase activity
GO992_01575	COG1024	Enoyl-CoA hydratase
GO992_01580	COG1024	Enoyl-CoA hydratase
GO992_01600	COG0730	response to heat
GO992_01620	COG3328	transposase activity
GO992_01640	COG1609	Transcriptional regulator
GO992_01645	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
GO992_01645	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
GO992_01650	COG1105	Belongs to the carbohydrate kinase PfkB family
GO992_01655	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GO992_01655	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GO992_01655	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
GO992_01660	COG3313	Fe-S protein
GO992_01665	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
GO992_01670	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
GO992_01675	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
GO992_01680	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
GO992_01690	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
GO992_01710	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
GO992_01715	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
GO992_01720	COG0291	Belongs to the bacterial ribosomal protein bL35 family
GO992_01725	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
GO992_01730	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
GO992_01735	COG0072	phenylalanine-tRNA ligase activity
GO992_01735	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GO992_01740	COG0776	regulation of translation
GO992_01760	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
GO992_01770	COG5001	Diguanylate cyclase
GO992_01770	COG3300	MHYT domain
GO992_01775	COG1609	Transcriptional regulator
GO992_01780	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GO992_01785	COG1879	ABC-type sugar transport system periplasmic component
GO992_01790	COG1172	Belongs to the binding-protein-dependent transport system permease family
GO992_01795	COG1129	ABC transporter
GO992_01800	COG1869	D-ribose catabolic process
GO992_01805	COG0625	glutathione transferase activity
GO992_01820	COG0037	tRNA processing
GO992_01825	COG0589	response to stress
GO992_01830	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
GO992_01845	COG2217	Heavy metal translocating P-type atpase
GO992_01855	COG2010	Cytochrome c
GO992_01870	COG3278	Belongs to the heme-copper respiratory oxidase family
GO992_01880	COG1956	GAF domain-containing protein
GO992_01885	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
GO992_01895	COG0308	aminopeptidase N
GO992_01920	COG0167	dihydroorotate dehydrogenase activity
GO992_01940	COG3867	Arabinogalactan endo-beta-1,4-galactanase
GO992_01945	COG1874	Beta-galactosidase
GO992_01960	COG0257	Belongs to the bacterial ribosomal protein bL36 family
GO992_01965	COG0254	rRNA binding
GO992_01980	COG1451	nucleotide metabolic process
GO992_01995	COG3069	C4-dicarboxylate transmembrane transporter activity
GO992_02005	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
GO992_02005	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
GO992_02010	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
GO992_02030	COG2009	succinate dehydrogenase
GO992_02035	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
GO992_02040	COG1053	succinate dehydrogenase
GO992_02050	COG0567	Dehydrogenase, E1 component
GO992_02055	COG0508	dehydrogenase complex catalyzes the overall conversion of
GO992_02060	COG0045	succinate-CoA ligase (ADP-forming) activity
GO992_02065	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
GO992_02075	COG1882	Formate acetyltransferase
GO992_02080	COG2116	formate transmembrane transporter activity
GO992_02085	COG1944	ATP diphosphatase activity
GO992_02090	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
GO992_02105	COG5433	transposase activity
GO992_02150	COG4681	YaeQ
GO992_02170	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GO992_02190	COG3134	Outer membrane lipoprotein
GO992_02200	COG1288	antiporter activity
GO992_02235	COG0058	SHG alpha-glucan phosphorylase activity
GO992_02240	COG0471	metal ion transport
GO992_02245	COG3118	belongs to the thioredoxin family
GO992_02260	COG1132	(ABC) transporter
GO992_02270	COG2501	S4 domain
GO992_02280	COG3243	poly(R)-hydroxyalkanoic acid synthase
GO992_02300	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
GO992_02305	COG2329	Antibiotic biosynthesis monooxygenase
GO992_02355	COG1742	UPF0060 membrane protein
GO992_02370	COG0513	Belongs to the DEAD box helicase family
GO992_02375	COG0386	Belongs to the glutathione peroxidase family
GO992_02385	COG1181	Belongs to the D-alanine--D-alanine ligase family
GO992_02400	COG0730	response to heat
GO992_02405	COG0583	DNA-binding transcription factor activity
GO992_02420	COG3593	DNA synthesis involved in DNA repair
GO992_02480	COG1011	Hydrolase
GO992_02495	COG5433	transposase activity
GO992_02580	COG2840	Smr protein MutS2
GO992_02585	COG2890	protein-(glutamine-N5) methyltransferase activity
GO992_02590	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
GO992_02600	COG0513	Belongs to the DEAD box helicase family
GO992_02605	COG5654	RES domain protein
GO992_02630	COG1067	ATP-dependent peptidase activity
GO992_02635	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
GO992_02660	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
GO992_02660	COG0116	Belongs to the methyltransferase superfamily
GO992_02670	COG3620	sequence-specific DNA binding
GO992_02700	COG4221	oxidoreductase activity
GO992_02745	COG0372	Belongs to the citrate synthase family
GO992_02750	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
GO992_02760	COG2995	paraquat-inducible protein a
GO992_02765	COG3008	intermembrane lipid transfer
GO992_02770	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
GO992_02770	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
GO992_02785	COG0084	hydrolase, TatD family'
GO992_02790	COG0470	DNA polymerase III
GO992_02795	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
GO992_02800	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
GO992_02805	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
GO992_02810	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
GO992_02815	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
GO992_02820	COG1028	Short-chain dehydrogenase reductase Sdr
GO992_02830	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
GO992_02835	COG0416	fatty acid biosynthetic process
GO992_02840	COG0333	Belongs to the bacterial ribosomal protein bL32 family
GO992_02845	COG1399	metal-binding, possibly nucleic acid-binding protein
GO992_02850	COG0424	maF-like protein
GO992_02865	COG1530	ribonuclease E activity
GO992_02875	COG0717	Belongs to the dCTP deaminase family
GO992_02880	COG0572	uridine kinase
GO992_02885	COG0489	protein tyrosine kinase activity
GO992_02890	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GO992_02890	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GO992_02895	COG0625	glutathione transferase activity
GO992_02900	COG1254	Belongs to the acylphosphatase family
GO992_02915	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
GO992_02930	COG0709	Synthesizes selenophosphate from selenide and ATP
GO992_02935	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
GO992_02940	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GO992_02945	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
GO992_02955	COG1643	Atp-dependent helicase
GO992_02965	COG2197	response regulator
GO992_02975	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
GO992_02980	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
GO992_02985	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
GO992_02990	COG2832	Protein of unknown function (DUF454)
GO992_02995	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
GO992_03015	COG0318	PFAM AMP-dependent synthetase and ligase
GO992_03020	COG2267	carboxylic ester hydrolase activity
GO992_03030	COG1214	PFAM Peptidase M22, glycoprotease
GO992_03035	COG1199	ATP-dependent helicase activity
GO992_03045	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
GO992_03050	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
GO992_03055	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
GO992_03060	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
GO992_03060	COG0131	Imidazoleglycerol-phosphate dehydratase
GO992_03065	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
GO992_03070	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
GO992_03085	COG0784	Response regulator, receiver
GO992_03085	COG2198	Histidine kinase
GO992_03085	COG2205	protein histidine kinase activity
GO992_03090	COG0107	imidazoleglycerol-phosphate synthase activity
GO992_03095	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
GO992_03095	COG0140	phosphoribosyl-ATP diphosphatase activity
GO992_03105	COG2378	regulation of single-species biofilm formation
GO992_03135	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
GO992_03145	COG0814	amino acid
GO992_03150	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
GO992_03155	COG0514	ATP-dependent DNA helicase (RecQ)
GO992_03160	COG2766	serine protein kinase
GO992_03170	COG2719	SpoVR family
GO992_03175	COG2186	Transcriptional regulator
GO992_03180	COG3067	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
GO992_03185	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
GO992_03190	COG0586	Pfam SNARE associated Golgi protein
GO992_03200	COG0556	nucleotide-excision repair
GO992_03210	COG0569	domain protein
GO992_03210	COG2985	domain, Protein
GO992_03215	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
GO992_03235	COG4565	transcriptional regulatory protein
GO992_03245	COG1846	Transcriptional regulator
GO992_03245	COG1940	carbohydrate kinase activity
GO992_03250	COG0840	transmembrane signaling receptor activity
GO992_03255	COG3012	SEC-C Motif Domain Protein
GO992_03260	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
GO992_03265	COG3075	Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses fumarate or nitrate as electron acceptor
GO992_03270	COG0247	lactate metabolic process
GO992_03280	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
GO992_03285	COG0437	4 iron, 4 sulfur cluster binding
GO992_03290	COG3301	Polysulphide reductase, NrfD
GO992_03305	COG3088	subunit of a heme lyase
GO992_03305	COG4235	cytochrome complex assembly
GO992_03320	COG3033	Beta-eliminating lyase
GO992_03335	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
GO992_03370	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
GO992_03385	COG4774	siderophore transport
GO992_03390	COG3708	Transcriptional regulator
GO992_03390	COG2207	Transcriptional regulator
GO992_03400	COG0583	DNA-binding transcription factor activity
GO992_03450	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
GO992_03455	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
GO992_03460	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
GO992_03470	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
GO992_03475	COG1434	Gram-negative-bacterium-type cell wall biogenesis
GO992_03485	COG0205	6-phosphofructokinase activity
GO992_03550	COG2824	Alkylphosphonate utilization operon protein PhnA
GO992_03555	COG1024	Enoyl-CoA hydratase
GO992_03555	COG1250	3-hydroxyacyl-CoA dehydrogenase
GO992_03560	COG0183	Belongs to the thiolase family
GO992_03565	COG0714	Associated with various cellular activities
GO992_03605	COG2067	long-chain fatty acid transport protein
GO992_03610	COG2067	long-chain fatty acid transport protein
GO992_03615	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
GO992_03635	COG3123	guanosine phosphorylase activity
GO992_03640	COG1760	l-serine dehydratase
GO992_03645	COG1760	l-serine dehydratase
GO992_03650	COG2951	lytic endotransglycosylase activity
GO992_03655	COG3100	YcgL domain-containing protein
GO992_03660	COG0850	regulation of cytokinetic process
GO992_03665	COG2894	cell division
GO992_03670	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
GO992_03680	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
GO992_03720	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
GO992_03725	COG0697	spore germination
GO992_03730	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
GO992_03735	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
GO992_03745	COG0307	riboflavin synthase, alpha
GO992_03755	COG0534	Mate efflux family protein
GO992_03790	COG0417	DNA replication proofreading
GO992_03800	COG2203	Gaf domain
GO992_03800	COG2199	diguanylate cyclase activity
GO992_03815	COG1560	Kdo2-lipid A biosynthetic process
GO992_03820	COG1560	Kdo2-lipid A biosynthetic process
GO992_03830	COG0583	DNA-binding transcription factor activity
GO992_03835	COG0673	inositol 2-dehydrogenase activity
GO992_03840	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
GO992_03845	COG0583	DNA-binding transcription factor activity
GO992_03855	COG2723	6-phospho-beta-galactosidase activity
GO992_03860	COG0583	DNA-binding transcription factor activity
GO992_03865	COG5433	transposase activity
GO992_03930	COG4580	involved in the transport of maltose and maltodextrins
GO992_03935	COG1609	Transcriptional regulator
GO992_03940	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
GO992_03950	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
GO992_03960	COG1172	Belongs to the binding-protein-dependent transport system permease family
GO992_03965	COG1129	ABC transporter
GO992_03970	COG1879	ABC-type sugar transport system periplasmic component
GO992_03975	COG1069	ribulokinase activity
GO992_03985	COG2160	L-arabinose isomerase activity
GO992_03990	COG0583	DNA-binding transcription factor activity
GO992_03995	COG0436	Aminotransferase
GO992_04000	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
GO992_04015	COG2925	Exonuclease
GO992_04025	COG3345	alpha-galactosidase
GO992_04030	COG1380	Effector of murein hydrolase LrgA
GO992_04035	COG1346	cytolysis
GO992_04040	COG0295	cytidine deaminase activity
GO992_04045	COG1022	Amp-dependent synthetase and ligase
GO992_04060	COG0861	Integral membrane protein TerC family
GO992_04070	COG2199	diguanylate cyclase activity
GO992_04085	COG2154	pterin-4-alpha-carbinolamine dehydratase
GO992_04095	COG3768	UPF0283 membrane protein
GO992_04100	COG3106	COG3106 Predicted ATPase
GO992_04115	COG1842	Phage shock protein A
GO992_04120	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
GO992_04130	COG4168	peptide transport system, permease
GO992_04135	COG4171	peptide transport system, permease
GO992_04140	COG4172	Belongs to the ABC transporter superfamily
GO992_04145	COG4172	Belongs to the ABC transporter superfamily
GO992_04155	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
GO992_04160	COG1286	toxin biosynthetic process
GO992_04165	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
GO992_04170	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
GO992_04175	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
GO992_04180	COG0531	amino acid
GO992_04180	COG1674	ftsk spoiiie
GO992_04200	COG0492	ferredoxin-NADP+ reductase activity
GO992_04210	COG3134	Outer membrane lipoprotein
GO992_04215	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
GO992_04220	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
GO992_04225	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
GO992_04230	COG0542	response to heat
GO992_04235	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
GO992_04240	COG1278	Cold shock
GO992_04245	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
GO992_04360	COG0659	secondary active sulfate transmembrane transporter activity
GO992_04390	COG0697	spore germination
GO992_04395	COG4657	Part of a membrane complex involved in electron transport
GO992_04400	COG2878	Part of a membrane complex involved in electron transport
GO992_04410	COG4658	electron transport chain
GO992_04415	COG4659	FMN binding
GO992_04425	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
GO992_04430	COG0346	lactoylglutathione lyase activity
GO992_04445	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
GO992_04450	COG2056	Na+-H+ antiporter family
GO992_04455	COG3328	transposase activity
GO992_04470	COG0513	Belongs to the DEAD box helicase family
GO992_04475	COG2050	protein possibly involved in aromatic compounds catabolism
GO992_04485	COG0277	FAD linked oxidase domain protein
GO992_04485	COG0247	lactate metabolic process
GO992_04495	COG1253	flavin adenine dinucleotide binding
GO992_04500	COG1902	pentaerythritol trinitrate reductase activity
GO992_04505	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
GO992_04510	COG0647	UMP catabolic process
GO992_04515	COG4651	solute:proton antiporter activity
GO992_04515	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
GO992_04525	COG0367	asparagine synthase
GO992_04550	COG0625	glutathione transferase activity
GO992_04555	COG0625	glutathione transferase activity
GO992_04580	COG0564	pseudouridine synthase activity
GO992_04600	COG0840	transmembrane signaling receptor activity
GO992_04610	COG0670	Belongs to the BI1 family
GO992_04615	COG1289	transmembrane transporter activity
GO992_04620	COG2920	part of a sulfur-relay system
GO992_04625	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
GO992_04630	COG0285	dihydrofolate synthase activity
GO992_04635	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
GO992_04640	COG0101	tRNA pseudouridine synthase activity
GO992_04650	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
GO992_04655	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
GO992_04660	COG0671	phosphoesterase, PA-phosphatase related
GO992_04735	COG0574	Belongs to the PEP-utilizing enzyme family
GO992_04735	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
GO992_04740	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
GO992_04780	COG0672	)-iron permease
GO992_04805	COG2814	Major facilitator Superfamily
GO992_04820	COG1136	(ABC) transporter
GO992_04840	COG1285	pathogenesis
GO992_04895	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
GO992_04900	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
GO992_04900	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
GO992_04940	COG0393	Putative heavy-metal-binding
GO992_04945	COG1252	NADH dehydrogenase
GO992_04975	COG2916	Histone family protein nucleoid-structuring protein H-NS
GO992_04980	COG2096	Adenosyltransferase
GO992_04985	COG3530	Putative quorum-sensing-regulated virulence factor
GO992_04990	COG0602	queuosine metabolic process
GO992_04995	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
GO992_05010	COG0284	orotidine-5'-phosphate decarboxylase activity
GO992_05015	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
GO992_05025	COG0776	regulation of translation
GO992_05030	COG0539	negative regulation of cytoplasmic translation
GO992_05035	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
GO992_05040	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
GO992_05050	COG0583	DNA-binding transcription factor activity
GO992_05055	COG2814	Major facilitator Superfamily
GO992_05075	COG3300	MHYT domain
GO992_05075	COG5001	Diguanylate cyclase
GO992_05090	COG0583	DNA-binding transcription factor activity
GO992_05120	COG4989	oxidoreductase activity
GO992_05125	COG0724	RNA recognition motif
GO992_05150	COG1570	exodeoxyribonuclease VII activity
GO992_05165	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
GO992_05170	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
GO992_05175	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
GO992_05195	COG0644	oxidoreductase
GO992_05195	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
GO992_05200	COG0598	Magnesium transport protein CorA
GO992_05220	COG4771	TonB-dependent receptor
GO992_05225	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GO992_05230	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GO992_05235	COG1120	ATPase activity
GO992_05240	COG2977	Belongs to the P-Pant transferase superfamily
GO992_05245	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
GO992_05250	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GO992_05250	COG1028	Short-chain dehydrogenase reductase Sdr
GO992_05250	COG3321	synthase
GO992_05250	COG0300	oxidoreductase activity
GO992_05250	COG0318	PFAM AMP-dependent synthetase and ligase
GO992_05260	COG1028	Short-chain dehydrogenase reductase Sdr
GO992_05265	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GO992_05270	COG3433	isochorismatase activity
GO992_05270	COG1535	isochorismatase
GO992_05275	COG1021	2,3-dihydroxybenzoate-AMP ligase
GO992_05300	COG3300	MHYT domain
GO992_05300	COG5001	Diguanylate cyclase
GO992_05315	COG0840	transmembrane signaling receptor activity
GO992_05320	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GO992_05325	COG3788	relative of glutathione S-transferase, MAPEG superfamily
GO992_05330	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
GO992_05335	COG0563	adenylate kinase activity
GO992_05345	COG0326	Molecular chaperone. Has ATPase activity
GO992_05370	COG5433	transposase activity
GO992_05395	COG5433	transposase activity
GO992_05400	COG3321	synthase
GO992_05400	COG1028	Short-chain dehydrogenase reductase Sdr
GO992_05400	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GO992_05400	COG4221	oxidoreductase activity
GO992_05410	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GO992_05430	COG0217	transcriptional regulatory protein
GO992_05435	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
GO992_05455	COG4106	trans-aconitate 2-methyltransferase activity
GO992_05460	COG0500	methyltransferase
GO992_05480	COG0450	alkyl hydroperoxide reductase
GO992_05485	COG5433	transposase activity
GO992_05495	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
GO992_05510	COG0455	bacterial-type flagellum organization
GO992_05520	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
GO992_05530	COG1684	flagellar biosynthetic protein fliR
GO992_05535	COG1987	bacterial-type flagellum assembly
GO992_05585	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
GO992_05595	COG1677	Flagellar hook-basal body complex protein FliE
GO992_05605	COG1574	metal-dependent hydrolase with the TIM-barrel fold
GO992_05620	COG1342	Belongs to the UPF0251 family
GO992_05640	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
GO992_05655	COG3290	protein histidine kinase activity
GO992_05665	COG1737	Transcriptional regulator
GO992_05670	COG0469	pyruvate kinase activity
GO992_05680	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
GO992_05685	COG1960	acyl-CoA dehydrogenase activity
GO992_05700	COG5433	transposase activity
GO992_05710	COG5433	transposase activity
GO992_05735	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
GO992_05745	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
GO992_05750	COG2261	transglycosylase associated protein
GO992_05790	COG0322	excinuclease ABC activity
GO992_05795	COG2197	response regulator
GO992_05800	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
GO992_05805	COG2835	tetraacyldisaccharide 4'-kinase activity
GO992_05810	COG1663	tetraacyldisaccharide 4'-kinase activity
GO992_05815	COG1132	(ABC) transporter
GO992_05820	COG0658	competence protein
GO992_05820	COG2333	competence protein COMEC
GO992_05835	COG0433	COG0433 Predicted ATPase
GO992_05840	COG1448	Aminotransferase
GO992_05855	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
GO992_05860	COG1199	ATP-dependent helicase activity
GO992_05870	COG0123	including yeast histone deacetylase and acetoin utilization protein
GO992_05875	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
GO992_05880	COG1785	Belongs to the alkaline phosphatase family
GO992_05900	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
GO992_05915	COG2271	Major facilitator Superfamily
GO992_05920	COG3706	GGDEF domain
GO992_05925	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GO992_05930	COG0765	amino acid transport
GO992_05935	COG1126	abc transporter atp-binding protein
GO992_05945	COG0531	amino acid
GO992_05960	COG1253	flavin adenine dinucleotide binding
GO992_05965	COG0704	Plays a role in the regulation of phosphate uptake
GO992_05975	COG0581	inorganic phosphate transmembrane transporter activity
GO992_05980	COG0573	inorganic phosphate transmembrane transporter activity
GO992_05995	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
GO992_06015	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
GO992_06020	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
GO992_06025	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
GO992_06030	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
GO992_06035	COG2204	response regulator
GO992_06040	COG3852	Histidine kinase
GO992_06045	COG2204	response regulator
GO992_06060	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
GO992_06065	COG0248	Ppx GppA phosphatase
GO992_06070	COG2239	Acts as a magnesium transporter
GO992_06105	COG0622	Phosphoesterase
GO992_06110	COG4166	transmembrane transport
GO992_06120	COG1187	pseudouridine synthase activity
GO992_06135	COG0697	spore germination
GO992_06165	COG1278	Cold shock
GO992_06215	COG3132	Protein of unknown function, DUF480
GO992_06225	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
GO992_06255	COG0583	DNA-binding transcription factor activity
GO992_06260	COG2610	gluconate transmembrane transporter activity
GO992_06265	COG3048	D-serine ammonia-lyase activity
GO992_06275	COG0538	isocitrate dehydrogenase activity
GO992_06280	COG2207	Transcriptional regulator
GO992_06295	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GO992_06320	COG5433	transposase activity
GO992_06350	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GO992_06355	COG3706	GGDEF domain
GO992_06360	COG1752	Esterase of the alpha-beta hydrolase superfamily
GO992_06365	COG0733	neurotransmitter:sodium symporter activity
GO992_06390	COG2885	chlorophyll binding
GO992_06390	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
GO992_06395	COG0281	malic enzyme
GO992_06400	COG2207	Transcriptional regulator
GO992_06405	COG0534	Mate efflux family protein
GO992_06415	COG0745	RESPONSE REGULATOR receiver
GO992_06415	COG3706	GGDEF domain
GO992_06420	COG2233	PERMEase
GO992_06425	COG0095	Lipoate-protein ligase
GO992_06430	COG1115	amino acid carrier protein
GO992_06435	COG0019	diaminopimelate decarboxylase activity
GO992_06455	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
GO992_06475	COG1131	(ABC) transporter
GO992_06480	COG0545	Peptidyl-prolyl cis-trans isomerase
GO992_06485	COG3142	Participates in the control of copper homeostasis
GO992_06490	COG1940	carbohydrate kinase activity
GO992_06500	COG4783	chaperone-mediated protein folding
GO992_06510	COG5002	protein histidine kinase activity
GO992_06515	COG0745	RESPONSE REGULATOR receiver
GO992_06520	COG0346	lactoylglutathione lyase activity
GO992_06525	COG3706	GGDEF domain
GO992_06530	COG3284	Transcriptional regulator
GO992_06535	COG1012	belongs to the aldehyde dehydrogenase family
GO992_06540	COG1942	4-Oxalocrotonate Tautomerase
GO992_06545	COG2267	carboxylic ester hydrolase activity
GO992_06565	COG0697	spore germination
GO992_06575	COG0667	Aldo Keto reductase
GO992_06590	COG3290	protein histidine kinase activity
GO992_06595	COG0281	malic enzyme
GO992_06660	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GO992_06670	COG0281	malic enzyme
GO992_06685	COG0437	4 iron, 4 sulfur cluster binding
GO992_06690	COG3383	formate dehydrogenase (NAD+) activity
GO992_06735	COG5433	transposase activity
GO992_06755	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
GO992_06795	COG0471	metal ion transport
GO992_06795	COG3273	potassium ion transport
GO992_06815	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
GO992_06820	COG0438	transferase activity, transferring glycosyl groups
GO992_06840	COG1450	Type ii and iii secretion system protein
GO992_06880	COG1459	type II secretion system
GO992_06885	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
GO992_06905	COG1091	dTDP-4-dehydrorhamnose reductase activity
GO992_06915	COG1538	Outer membrane efflux protein
GO992_06925	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GO992_06930	COG1309	transcriptional regulator
GO992_06945	COG1946	Acyl-CoA thioesterase
GO992_06955	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
GO992_06965	COG0009	L-threonylcarbamoyladenylate synthase
GO992_06970	COG0613	PHP domain protein
GO992_06975	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
GO992_06980	COG0512	Glutamine amidotransferase of anthranilate synthase
GO992_06980	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
GO992_06985	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
GO992_06990	COG0134	indole-3-glycerol-phosphate synthase activity
GO992_06990	COG0135	phosphoribosylanthranilate isomerase activity
GO992_06995	COG0133	tryptophan synthase activity
GO992_07000	COG0159	tryptophan synthase activity
GO992_07020	COG1388	LysM domain
GO992_07020	COG1376	ErfK ybiS ycfS ynhG family protein
GO992_07035	COG3129	Specifically methylates the adenine in position 1618 of 23S rRNA
GO992_07040	COG0791	NLP P60 protein
GO992_07045	COG2091	lysine biosynthetic process via aminoadipic acid
GO992_07050	COG3118	belongs to the thioredoxin family
GO992_07060	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
GO992_07065	COG0788	formyltetrahydrofolate deformylase activity
GO992_07095	COG0366	Alpha amylase catalytic
GO992_07100	COG0741	lytic transglycosylase activity
GO992_07100	COG0739	heme binding
GO992_07100	COG1196	nuclear chromosome segregation
GO992_07105	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
GO992_07110	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
GO992_07115	COG0673	inositol 2-dehydrogenase activity
GO992_07140	COG2814	Major facilitator Superfamily
GO992_07145	COG0109	protoheme IX farnesyltransferase activity
GO992_07155	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
GO992_07160	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
GO992_07225	COG0708	Exodeoxyribonuclease III
GO992_07250	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GO992_07255	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
GO992_07265	COG0095	Lipoate-protein ligase
GO992_07295	COG0640	Transcriptional regulator
GO992_07310	COG1285	pathogenesis
GO992_07340	COG0484	heat shock protein binding
GO992_07345	COG0443	Heat shock 70 kDa protein
GO992_07350	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
GO992_07355	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
GO992_07360	COG0497	DNA recombination
GO992_07365	COG1227	inorganic diphosphatase activity
GO992_07375	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GO992_07380	COG0577	efflux transmembrane transporter activity
GO992_07380	COG1136	(ABC) transporter
GO992_07385	COG1538	Outer membrane efflux protein
GO992_07390	COG2375	cellular response to nickel ion
GO992_07395	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
GO992_07405	COG3328	transposase activity
GO992_07410	COG2916	Histone family protein nucleoid-structuring protein H-NS
GO992_07445	COG2169	Transcriptional regulator
GO992_07445	COG1917	Cupin 2, conserved barrel domain protein
GO992_07460	COG1917	Cupin 2, conserved barrel domain protein
GO992_07460	COG1396	sequence-specific DNA binding
GO992_07475	COG0531	amino acid
GO992_07480	COG0531	amino acid
GO992_07485	COG1283	sodium-dependent phosphate transmembrane transporter activity
GO992_07495	COG3384	dioxygenase
GO992_07510	COG0813	purine-nucleoside phosphorylase activity
GO992_07535	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
GO992_07540	COG0083	homoserine kinase activity
GO992_07555	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
GO992_07560	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
GO992_07575	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
GO992_07585	COG0745	RESPONSE REGULATOR receiver
GO992_07600	COG4988	ABC transporter
GO992_07605	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
GO992_07625	COG1720	tRNA m6t6A37 methyltransferase activity
GO992_07645	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
GO992_07650	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
GO992_07660	COG2190	(PTS) system
GO992_07665	COG3706	GGDEF domain
GO992_07675	COG3038	cytochrome b561
GO992_07685	COG0419	ATPase involved in DNA repair
GO992_07690	COG0420	3'-5' exonuclease activity
GO992_07700	COG2974	May be involved in recombination
GO992_07710	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
GO992_07710	COG4651	solute:proton antiporter activity
GO992_07715	COG4651	solute:proton antiporter activity
GO992_07715	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
GO992_07730	COG0469	pyruvate kinase activity
GO992_07735	COG3264	Mechanosensitive ion channel
GO992_07735	COG1196	nuclear chromosome segregation
GO992_07740	COG0582	viral genome integration into host DNA
GO992_07760	COG1846	Transcriptional regulator
GO992_07765	COG1566	PFAM secretion protein HlyD family protein
GO992_07790	COG0602	queuosine metabolic process
GO992_07800	COG1328	CTP reductase activity
GO992_07810	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
GO992_07815	COG3115	cell septum assembly
GO992_07820	COG1196	nuclear chromosome segregation
GO992_07830	COG2860	membrane
GO992_07840	COG3108	Peptidase M15
GO992_07845	COG2989	Protein conserved in bacteria
GO992_07855	COG5433	transposase activity
GO992_07865	COG0463	Glycosyl transferase, family 2
GO992_07880	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
GO992_07885	COG0739	heme binding
GO992_07890	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
GO992_07895	COG5433	transposase activity
GO992_07925	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
GO992_07935	COG3091	SprT-like family
GO992_07945	COG1385	rRNA (uridine-N3-)-methyltransferase activity
GO992_07950	COG0189	ligase activity
GO992_07965	COG1678	Uncharacterized ACR, COG1678
GO992_07970	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
GO992_07975	COG0583	DNA-binding transcription factor activity
GO992_08000	COG0714	Associated with various cellular activities
GO992_08015	COG1115	amino acid carrier protein
GO992_08020	COG5433	transposase activity
GO992_08025	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
GO992_08040	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
GO992_08060	COG1301	dicarboxylic acid transport
GO992_08070	COG2912	Transglutaminase-like superfamily
GO992_08080	COG2890	protein-(glutamine-N5) methyltransferase activity
GO992_08085	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
GO992_08090	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
GO992_08095	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
GO992_08100	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
GO992_08110	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
GO992_08115	COG0737	Belongs to the 5'-nucleotidase family
GO992_08120	COG0193	aminoacyl-tRNA hydrolase activity
GO992_08125	COG0012	GTP binding
GO992_08170	COG0490	domain, Protein
GO992_08170	COG0471	metal ion transport
GO992_08180	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
GO992_08215	COG0463	Glycosyl transferase, family 2
GO992_08230	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
GO992_08235	COG2076	Multidrug Resistance protein
GO992_08240	COG2076	Multidrug Resistance protein
GO992_08245	COG3954	Phosphoribulokinase
GO992_08260	COG1765	OsmC-like protein
GO992_08265	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
GO992_08275	COG3397	chitin binding
GO992_08290	COG2202	Pas domain
GO992_08290	COG2205	protein histidine kinase activity
GO992_08300	COG3655	Transcriptional regulator
GO992_08310	COG2814	Major facilitator Superfamily
GO992_08315	COG4771	TonB-dependent receptor
GO992_08335	COG0748	coenzyme F420 binding
GO992_08340	COG3721	Heme iron utilization protein
GO992_08350	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GO992_08375	COG0488	(ABC) transporter
GO992_08385	COG2252	PERMEase
GO992_08390	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
GO992_08395	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
GO992_08400	COG3178	'Phosphotransferase
GO992_08405	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
GO992_08415	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
GO992_08420	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
GO992_08430	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
GO992_08445	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GO992_08465	COG0318	PFAM AMP-dependent synthetase and ligase
GO992_08475	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
GO992_08480	COG0211	Belongs to the bacterial ribosomal protein bL27 family
GO992_08485	COG0261	This protein binds to 23S rRNA in the presence of protein L20
GO992_08490	COG0142	geranyltranstransferase activity
GO992_08495	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
GO992_08500	COG0330	HflC and HflK could
GO992_08505	COG0330	HflC and HflK could
GO992_08510	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
GO992_08515	COG1923	regulation of RNA biosynthetic process
GO992_08520	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
GO992_08525	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
GO992_08535	COG0802	atpase or kinase
GO992_08540	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
GO992_08540	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
GO992_08560	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
GO992_08565	COG2011	ABC-type metal ion transport system permease component
GO992_08570	COG1464	Belongs to the NlpA lipoprotein family
GO992_08605	COG5002	protein histidine kinase activity
GO992_08605	COG2198	Histidine kinase
GO992_08605	COG0784	Response regulator, receiver
GO992_08640	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
GO992_08645	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
GO992_08655	COG2716	regulation of RNA biosynthetic process
GO992_08660	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
GO992_08665	COG3013	Belongs to the UPF0304 family
GO992_08670	COG3092	negative regulation of chromosome organization
GO992_08675	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
GO992_08680	COG0857	belongs to the CobB CobQ family
GO992_08680	COG0280	phosphate acetyltransferase
GO992_08685	COG0440	acetolactate synthase activity
GO992_08690	COG0028	Belongs to the TPP enzyme family
GO992_08705	COG0671	phosphoesterase, PA-phosphatase related
GO992_08715	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
GO992_08720	COG0473	3-isopropylmalate dehydrogenase activity
GO992_08725	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
GO992_08730	COG0066	3-isopropylmalate dehydratase activity
GO992_08745	COG4143	(ABC) transporter
GO992_08750	COG1178	ABC-type Fe3 transport system permease component
GO992_08755	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
GO992_08760	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
GO992_08770	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
GO992_08800	COG0316	Belongs to the HesB IscA family
GO992_08810	COG0038	chloride channel
GO992_08815	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
GO992_08830	COG0671	phosphoesterase, PA-phosphatase related
GO992_08840	COG0784	Response regulator, receiver
GO992_08840	COG3437	response regulator, receiver
GO992_08845	COG0583	DNA-binding transcription factor activity
GO992_08850	COG2076	Multidrug Resistance protein
GO992_08860	COG0346	lactoylglutathione lyase activity
GO992_08865	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
GO992_08870	COG1643	Atp-dependent helicase
GO992_08880	COG1489	DNA binding
GO992_08885	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
GO992_08890	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
GO992_08895	COG0617	tRNA 3'-terminal CCA addition
GO992_08900	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
GO992_08905	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
GO992_08910	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
GO992_08920	COG0842	Transport permease protein
GO992_08925	COG1131	(ABC) transporter
GO992_08940	COG0163	prenyltransferase activity
GO992_08945	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
GO992_08950	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
GO992_08955	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
GO992_08960	COG2816	NAD+ diphosphatase activity
GO992_08965	COG0506	proline dehydrogenase activity
GO992_08965	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
GO992_08965	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
GO992_08970	COG4991	sh3 domain protein
GO992_08975	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
GO992_08995	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
GO992_09000	COG1640	4-alpha-glucanotransferase
GO992_09005	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
GO992_09010	COG0676	glucose-6-phosphate 1-epimerase activity
GO992_09015	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
GO992_09020	COG0840	transmembrane signaling receptor activity
GO992_09085	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
GO992_09090	COG2885	chlorophyll binding
GO992_09095	COG0823	Involved in the tonB-independent uptake of proteins
GO992_09110	COG0811	peptide transport
GO992_09115	COG0824	Thioesterase
GO992_09120	COG3790	cyd operon protein YbgE
GO992_09125	COG4890	Cyd operon protein YbgT
GO992_09130	COG1294	oxidase, subunit
GO992_09135	COG1271	oxidase subunit
GO992_09140	COG2255	four-way junction helicase activity
GO992_09145	COG0632	four-way junction helicase activity
GO992_09150	COG0840	transmembrane signaling receptor activity
GO992_09155	COG0442	prolyl-tRNA aminoacylation
GO992_09165	COG1902	pentaerythritol trinitrate reductase activity
GO992_09175	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
GO992_09180	COG0745	RESPONSE REGULATOR receiver
GO992_09180	COG3706	GGDEF domain
GO992_09205	COG0714	Associated with various cellular activities
GO992_09215	COG0456	acetyltransferase
GO992_09225	COG1022	Amp-dependent synthetase and ligase
GO992_09235	COG2918	glutathione biosynthetic process
GO992_09240	COG0612	Peptidase, M16
GO992_09245	COG1238	metal cluster binding
GO992_09250	COG1064	alcohol dehydrogenase
GO992_09280	COG0359	binds to the 23S rRNA
GO992_09285	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
GO992_09290	COG0360	Binds together with S18 to 16S ribosomal RNA
GO992_09295	COG1914	H( )-stimulated, divalent metal cation uptake system
GO992_09300	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
GO992_09315	COG2153	protein acetylation
GO992_09325	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
GO992_09330	COG0557	exoribonuclease II activity
GO992_09335	COG3706	GGDEF domain
GO992_09340	COG1854	S-ribosylhomocysteine lyase activity
GO992_09355	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
GO992_09355	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
GO992_09390	COG4968	Prepilin-type N-terminal cleavage methylation domain
GO992_09395	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
GO992_09400	COG1047	Peptidyl-prolyl cis-trans
GO992_09405	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
GO992_09410	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
GO992_09415	COG0196	riboflavin kinase activity
GO992_09420	COG0728	peptidoglycan biosynthetic process
GO992_09425	COG0268	Binds directly to 16S ribosomal RNA
GO992_09430	COG0640	Transcriptional regulator
GO992_09435	COG0583	DNA-binding transcription factor activity
GO992_09445	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
GO992_09450	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
GO992_09455	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
GO992_09475	COG1051	belongs to the nudix hydrolase family
GO992_09480	COG3066	DNA modification
GO992_09490	COG0335	large ribosomal subunit rRNA binding
GO992_09495	COG0336	Belongs to the RNA methyltransferase TrmD family
GO992_09500	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
GO992_09505	COG0228	four-way junction DNA binding
GO992_09510	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
GO992_09515	COG4137	Cytochrome C assembly protein
GO992_09520	COG4536	flavin adenine dinucleotide binding
GO992_09525	COG1959	2 iron, 2 sulfur cluster binding
GO992_09530	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
GO992_09530	COG1017	nitric oxide dioxygenase activity
GO992_09535	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
GO992_09540	COG0039	L-malate dehydrogenase activity
GO992_09545	COG4160	amino acid transport
GO992_09550	COG4215	(ABC) transporter
GO992_09555	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GO992_09560	COG1126	abc transporter atp-binding protein
GO992_09565	COG1438	arginine binding
GO992_09570	COG2837	iron assimilation
GO992_09575	COG3842	ATPase activity
GO992_09585	COG1840	ABC-type Fe3 transport system, periplasmic component
GO992_09590	COG0347	Belongs to the P(II) protein family
GO992_09605	COG0004	ammonium transporteR
GO992_09610	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
GO992_09625	COG0084	hydrolase, TatD family'
GO992_09640	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
GO992_09645	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
GO992_09650	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
GO992_09655	COG0813	purine-nucleoside phosphorylase activity
GO992_09665	COG0560	Phosphoserine phosphatase
GO992_09690	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
GO992_09695	COG0776	regulation of translation
GO992_09710	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
GO992_09715	COG0735	belongs to the Fur family
GO992_09735	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
GO992_09740	COG0513	Belongs to the DEAD box helicase family
GO992_09745	COG3022	response to hydroperoxide
GO992_09760	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
GO992_09765	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
GO992_09770	COG0762	integral membrane protein
GO992_09775	COG1872	DUF167
GO992_09790	COG4166	transmembrane transport
GO992_09800	COG0110	maltose O-acetyltransferase activity
GO992_09810	COG1024	Enoyl-CoA hydratase
GO992_09825	COG4221	oxidoreductase activity
GO992_09835	COG2957	Belongs to the agmatine deiminase family
GO992_09860	COG0004	ammonium transporteR
GO992_09865	COG0347	Belongs to the P(II) protein family
GO992_09870	COG0745	RESPONSE REGULATOR receiver
GO992_09870	COG3706	GGDEF domain
GO992_09890	COG3706	GGDEF domain
GO992_09900	COG1278	Cold shock
GO992_09910	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
GO992_09915	COG2197	response regulator
GO992_09945	COG3568	Endonuclease Exonuclease Phosphatase
GO992_09960	COG0513	Belongs to the DEAD box helicase family
GO992_10000	COG1448	Aminotransferase
GO992_10015	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
GO992_10020	COG1328	CTP reductase activity
GO992_10060	COG1215	transferase activity, transferring glycosyl groups
GO992_10065	COG1649	PFAM Uncharacterised BCR, COG1649
GO992_10065	COG0726	polysaccharide deacetylase
GO992_10110	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
GO992_10115	COG4208	sulfate ABC transporter
GO992_10120	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
GO992_10130	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
GO992_10140	COG3174	membrane
GO992_10145	COG0110	maltose O-acetyltransferase activity
GO992_10175	COG1942	4-Oxalocrotonate Tautomerase
GO992_10185	COG0583	DNA-binding transcription factor activity
GO992_10190	COG0165	Argininosuccinate lyase
GO992_10230	COG0814	amino acid
GO992_10235	COG3932	Exopolysaccharide synthesis, ExoD
GO992_10290	COG1494	fructose-1,6-bisphosphatase
GO992_10305	COG2959	enzyme of heme biosynthesis
GO992_10315	COG0181	hydroxymethylbilane synthase activity
GO992_10320	COG3072	Adenylate cyclase
GO992_10325	COG0400	carboxylic ester hydrolase activity
GO992_10330	COG1965	Belongs to the frataxin family
GO992_10340	COG0019	diaminopimelate decarboxylase activity
GO992_10345	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
GO992_10360	COG1011	Hydrolase
GO992_10370	COG0668	transmembrane transport
GO992_10380	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
GO992_10385	COG0561	phosphatase activity
GO992_10400	COG0842	Transport permease protein
GO992_10400	COG1129	ABC transporter
GO992_10410	COG1546	Belongs to the CinA family
GO992_10410	COG1058	Belongs to the CinA family
GO992_10415	COG1418	mRNA catabolic process
GO992_10420	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
GO992_10430	COG1522	sequence-specific DNA binding
GO992_10435	COG1368	sulfuric ester hydrolase activity
GO992_10455	COG1285	pathogenesis
GO992_10475	COG4221	oxidoreductase activity
GO992_10495	COG1979	alcohol dehydrogenase
GO992_10505	COG2873	o-acetylhomoserine
GO992_10515	COG4533	DNA binding
GO992_10520	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
GO992_10535	COG5380	lipid catabolic process
GO992_10540	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
GO992_10555	COG2949	membrane
GO992_10560	COG3291	Pkd domain containing protein
GO992_10585	COG0187	DNA topoisomerase II activity
GO992_10595	COG1051	belongs to the nudix hydrolase family
GO992_10600	COG3150	esterase
GO992_10610	COG3151	Protein conserved in bacteria
GO992_10615	COG0494	nUDIX hydrolase
GO992_10620	COG1538	Outer membrane efflux protein
GO992_10625	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
GO992_10625	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
GO992_10630	COG1560	Kdo2-lipid A biosynthetic process
GO992_10645	COG1392	Phosphate transport regulator
GO992_10650	COG0306	phosphate transporter
GO992_10655	COG0617	tRNA 3'-terminal CCA addition
GO992_10660	COG3409	Peptidoglycan-binding domain 1 protein
GO992_10660	COG3267	Type II secretory pathway component ExeA
GO992_10670	COG1194	a g-specific adenine glycosylase
GO992_10675	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
GO992_10685	COG3111	PFAM Bacterial OB fold (BOF) protein
GO992_10690	COG3240	lipase activity
GO992_10705	COG3009	Protein conserved in bacteria
GO992_10710	COG3008	intermembrane lipid transfer
GO992_10710	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
GO992_10715	COG2995	paraquat-inducible protein a
GO992_10725	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
GO992_10740	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
GO992_10745	COG2813	Specifically methylates the guanine in position
GO992_10750	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
GO992_10755	COG0297	glycogen (starch) synthase activity
GO992_10790	COG1757	Na H antiporter
GO992_10800	COG0110	maltose O-acetyltransferase activity
GO992_10805	COG0366	Alpha amylase catalytic
GO992_10810	COG1263	PTS System
GO992_10810	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GO992_10825	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
GO992_10830	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
GO992_10835	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
GO992_10835	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
GO992_10840	COG2723	6-phospho-beta-galactosidase activity
GO992_10845	COG1447	Phosphotransferase system cellobiose-specific component IIA
GO992_10850	COG1940	carbohydrate kinase activity
GO992_10860	COG1609	Transcriptional regulator
GO992_10870	COG0252	asparaginase activity
GO992_10885	COG1803	Methylglyoxal synthase
GO992_10910	COG1444	tRNA N-acetyltransferase activity
GO992_10915	COG1028	Short-chain dehydrogenase reductase Sdr
GO992_10920	COG0784	Response regulator, receiver
GO992_10920	COG0835	chemotaxis
GO992_10960	COG5433	transposase activity
GO992_10965	COG0582	viral genome integration into host DNA
GO992_10980	COG0795	lipopolysaccharide-transporting ATPase activity
GO992_10985	COG0795	lipopolysaccharide-transporting ATPase activity
GO992_10990	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
GO992_10995	COG2927	DNA polymerase III (CHI subunit)
GO992_11010	COG0586	Pfam SNARE associated Golgi protein
GO992_11015	COG1686	Belongs to the peptidase S11 family
GO992_11040	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
GO992_11045	COG0527	aspartate kinase activity
GO992_11050	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
GO992_11060	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
GO992_11070	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
GO992_11105	COG1380	Effector of murein hydrolase LrgA
GO992_11110	COG1346	cytolysis
GO992_11125	COG0460	homoserine dehydrogenase
GO992_11125	COG0527	aspartate kinase activity
GO992_11130	COG0626	cystathionine gamma-synthase activity
GO992_11145	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GO992_11150	COG0814	amino acid
GO992_11155	COG1218	3'(2'),5'-bisphosphate nucleotidase
GO992_11160	COG0494	nUDIX hydrolase
GO992_11165	COG1011	Hydrolase
GO992_11170	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
GO992_11185	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
GO992_11195	COG3156	type II secretion system protein K
GO992_11200	COG4795	General secretion pathway protein
GO992_11205	COG2165	general secretion pathway protein
GO992_11215	COG2165	general secretion pathway protein
GO992_11220	COG1459	type II secretion system
GO992_11225	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
GO992_11245	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
GO992_11250	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
GO992_11270	COG0456	acetyltransferase
GO992_11275	COG3133	Outer membrane lipoprotein
GO992_11290	COG2771	luxR family
GO992_11305	COG4776	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction
GO992_11325	COG0246	Mannitol dehydrogenase
GO992_11330	COG3722	fumarate hydratase activity
GO992_11335	COG3263	regulation of cellular component size
GO992_11340	COG0484	heat shock protein binding
GO992_11360	COG1671	Belongs to the UPF0178 family
GO992_11375	COG1988	membrane-bound metal-dependent
GO992_11380	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
GO992_11400	COG0513	Belongs to the DEAD box helicase family
GO992_11420	COG5433	transposase activity
GO992_11435	COG1575	Belongs to the MenA family. Type 1 subfamily
GO992_11440	COG1169	isochorismate synthase
GO992_11445	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
GO992_11450	COG0596	Alpha beta hydrolase
GO992_11455	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
GO992_11465	COG0318	PFAM AMP-dependent synthetase and ligase
GO992_11485	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
GO992_11505	COG1929	Belongs to the glycerate kinase type-1 family
GO992_11510	COG2610	gluconate transmembrane transporter activity
GO992_11515	COG3835	regulator
GO992_11520	COG3112	Uncharacterised protein family (UPF0231)
GO992_11585	COG2259	Doxx family
GO992_11590	COG3118	belongs to the thioredoxin family
GO992_11610	COG0204	Acyl-transferase
GO992_11630	COG2827	Endonuclease containing a URI domain
GO992_11645	COG1573	uracil-dna glycosylase
GO992_11655	COG0583	DNA-binding transcription factor activity
GO992_11660	COG1108	ABC-type Mn2 Zn2 transport systems permease components
GO992_11665	COG1121	(ABC) transporter
GO992_11670	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
GO992_11690	COG0739	heme binding
GO992_11700	COG3068	Protein conserved in bacteria
GO992_11720	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
GO992_11740	COG0798	PFAM Bile acid sodium symporter
GO992_11745	COG1393	Belongs to the ArsC family
GO992_11755	COG2072	flavoprotein involved in K transport
GO992_11765	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
GO992_11775	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
GO992_11800	COG5433	transposase activity
GO992_11805	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
GO992_11810	COG1086	Polysaccharide biosynthesis protein
GO992_11815	COG0366	Alpha amylase catalytic
GO992_11830	COG0443	Heat shock 70 kDa protein
GO992_11835	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
GO992_11840	COG3045	CreA protein
GO992_11850	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
GO992_11855	COG0174	glutamine synthetase
GO992_11875	COG3842	ATPase activity
GO992_11880	COG1176	ABC-type spermidine putrescine transport system, permease component I
GO992_11885	COG1177	transmembrane transport
GO992_11890	COG2258	MOSC domain
GO992_11905	COG2050	protein possibly involved in aromatic compounds catabolism
GO992_11910	COG0514	ATP-dependent DNA helicase (RecQ)
GO992_11930	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
GO992_11935	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
GO992_11945	COG2239	Acts as a magnesium transporter
GO992_11950	COG1648	precorrin-2 dehydrogenase activity
GO992_11950	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
GO992_11955	COG2116	formate transmembrane transporter activity
GO992_11960	COG2146	nitrite reductase [NAD(P)H] activity
GO992_11965	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
GO992_11980	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
GO992_11985	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
GO992_11995	COG0018	arginyl-trna synthetase
GO992_12005	COG1595	DNA-templated transcription, initiation
GO992_12015	COG1968	undecaprenyl-diphosphatase activity
GO992_12020	COG0667	Aldo Keto reductase
GO992_12025	COG2017	converts alpha-aldose to the beta-anomer
GO992_12030	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
GO992_12040	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
GO992_12045	COG1609	Transcriptional regulator
GO992_12050	COG3250	beta-galactosidase activity
GO992_12065	COG4211	Belongs to the binding-protein-dependent transport system permease family
GO992_12075	COG3328	transposase activity
GO992_12095	COG5433	transposase activity
GO992_12125	COG0753	catalase activity
GO992_12130	COG1247	-acetyltransferase
GO992_12150	COG2203	Gaf domain
GO992_12150	COG2199	diguanylate cyclase activity
GO992_12160	COG3842	ATPase activity
GO992_12170	COG1176	ABC-type spermidine putrescine transport system, permease component I
GO992_12195	COG0583	DNA-binding transcription factor activity
GO992_12205	COG1741	Belongs to the pirin family
GO992_12210	COG2259	Doxx family
GO992_12215	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
GO992_12220	COG1074	ATP-dependent DNA helicase activity
GO992_12225	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
GO992_12290	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
GO992_12295	COG0745	RESPONSE REGULATOR receiver
GO992_12300	COG2205	protein histidine kinase activity
GO992_12310	COG0281	malic enzyme
GO992_12315	COG0702	epimerase
GO992_12320	COG0254	rRNA binding
GO992_12325	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
GO992_12335	COG1309	transcriptional regulator
GO992_12355	COG0129	dihydroxy-acid dehydratase activity
GO992_12360	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
GO992_12365	COG3978	acetolactate synthase activity
GO992_12380	COG0606	chelatase, subunit chli
GO992_12390	COG1683	Conserved Protein
GO992_12400	COG1335	isochorismatase
GO992_12410	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
GO992_12415	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
GO992_12425	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
GO992_12430	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
GO992_12440	COG3084	Protein conserved in bacteria
GO992_12445	COG4251	negative regulation of phosphorylation
GO992_12445	COG5001	Diguanylate cyclase
GO992_12445	COG2203	Gaf domain
GO992_12445	COG3706	GGDEF domain
GO992_12460	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
GO992_12470	COG1561	YicC-like family, N-terminal region
GO992_12515	COG5433	transposase activity
GO992_12530	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GO992_12545	COG1063	alcohol dehydrogenase
GO992_12570	COG0210	DNA helicase
GO992_12575	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
GO992_12580	COG2166	iron-sulfur cluster assembly
GO992_12585	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
GO992_12615	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
GO992_12620	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
GO992_12625	COG1739	Uncharacterized protein family UPF0029
GO992_12630	COG0006	proline dipeptidase activity
GO992_12635	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
GO992_12640	COG1250	3-hydroxyacyl-CoA dehydrogenase
GO992_12640	COG1024	Enoyl-CoA hydratase
GO992_12645	COG0183	Belongs to the thiolase family
GO992_12650	COG0745	RESPONSE REGULATOR receiver
GO992_12655	COG2205	protein histidine kinase activity
GO992_12670	COG0425	Belongs to the sulfur carrier protein TusA family
GO992_12675	COG0251	oxidation-reduction process
GO992_12680	COG2885	chlorophyll binding
GO992_12685	COG2818	Glycosylase
GO992_12690	COG0752	glycyl-tRNA synthetase alpha subunit
GO992_12695	COG0751	glycine-tRNA ligase activity
GO992_12705	COG3328	transposase activity
GO992_12745	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
GO992_12755	COG2199	diguanylate cyclase activity
GO992_12755	COG2200	EAL domain
GO992_12755	COG2202	Pas domain
GO992_12770	COG0814	amino acid
GO992_12775	COG0348	domain, Protein
GO992_12785	COG0446	pyridine nucleotide-disulphide oxidoreductase
GO992_12790	COG0426	domain, Protein
GO992_12790	COG1773	rubredoxin
GO992_12795	COG3604	Transcriptional regulator
GO992_12800	COG2188	Transcriptional regulator
GO992_12805	COG5433	transposase activity
GO992_12830	COG1609	Transcriptional regulator
GO992_12840	COG0559	Belongs to the binding-protein-dependent transport system permease family
GO992_12870	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
GO992_12895	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
GO992_12905	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
GO992_12910	COG3118	belongs to the thioredoxin family
GO992_12915	COG0513	Belongs to the DEAD box helicase family
GO992_12920	COG0248	Ppx GppA phosphatase
GO992_12930	COG0742	ribosomal rna small subunit methyltransferase
GO992_12935	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GO992_12955	COG0084	hydrolase, TatD family'
GO992_12960	COG0805	protein transport
GO992_12965	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
GO992_12975	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
GO992_12980	COG3165	ubiquinone biosynthetic process from chorismate
GO992_12990	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
GO992_12995	COG0402	S-adenosylhomocysteine deaminase activity
GO992_13035	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
GO992_13040	COG0848	biopolymer transport protein
GO992_13045	COG0811	peptide transport
GO992_13050	COG0811	peptide transport
GO992_13060	COG2771	luxR family
GO992_13065	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
GO992_13070	COG1349	DNA-binding transcription factor activity
GO992_13075	COG0745	RESPONSE REGULATOR receiver
GO992_13080	COG2205	protein histidine kinase activity
GO992_13090	COG4452	Inner membrane protein CreD
GO992_13095	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
GO992_13100	COG0355	proton-transporting ATP synthase activity, rotational mechanism
GO992_13105	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
GO992_13110	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
GO992_13115	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
GO992_13120	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
GO992_13125	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
GO992_13135	COG0356	it plays a direct role in the translocation of protons across the membrane
GO992_13140	COG3312	ion transport
GO992_13145	COG1475	DNA binding
GO992_13150	COG1192	Involved in chromosome partitioning
GO992_13155	COG0357	Ribosomal RNA small subunit methyltransferase G
GO992_13160	COG0445	tRNA wobble uridine modification
GO992_13165	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
GO992_13170	COG4774	siderophore transport
GO992_13175	COG4615	Cyclic peptide transporter
GO992_13180	COG1120	ATPase activity
GO992_13185	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
GO992_13195	COG4774	siderophore transport
GO992_13200	COG4607	ABC-type enterochelin transport system periplasmic component
GO992_13205	COG4604	ABC transporter, ATP-binding protein
GO992_13210	COG4605	iron ion homeostasis
GO992_13215	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GO992_13235	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GO992_13245	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GO992_13260	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
GO992_13265	COG0706	membrane insertase activity
GO992_13270	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
GO992_13275	COG0594	ribonuclease P activity
GO992_13280	COG0230	Belongs to the bacterial ribosomal protein bL34 family
GO992_13300	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
GO992_13305	COG0592	DNA-directed DNA polymerase activity
GO992_13315	COG0187	DNA topoisomerase II activity
GO992_13330	COG2378	regulation of single-species biofilm formation
GO992_13335	COG0071	Belongs to the small heat shock protein (HSP20) family
GO992_13340	COG0071	Belongs to the small heat shock protein (HSP20) family
GO992_13355	COG3977	Valine--pyruvate aminotransferase
GO992_13370	COG2814	Major facilitator Superfamily
GO992_13380	COG0745	RESPONSE REGULATOR receiver
GO992_13385	COG2205	protein histidine kinase activity
GO992_13410	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
GO992_13415	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GO992_13415	COG4191	Histidine kinase
GO992_13420	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
GO992_13425	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GO992_13430	COG1309	transcriptional regulator
GO992_13460	COG0561	phosphatase activity
GO992_13470	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
GO992_13475	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
GO992_13480	COG1758	RNA polymerase activity
GO992_13485	COG0194	GDP metabolic process
GO992_13495	COG0859	PFAM glycosyl transferase family 9
GO992_13500	COG3642	lipopolysaccharide core region biosynthetic process
GO992_13540	COG0589	response to stress
GO992_13545	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
GO992_13550	COG3706	GGDEF domain
GO992_13555	COG1528	Iron-storage protein
GO992_13560	COG2081	HI0933 family
GO992_13600	COG5433	transposase activity
GO992_13605	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GO992_13605	COG2205	protein histidine kinase activity
GO992_13615	COG3275	phosphorelay sensor kinase activity
GO992_13620	COG3279	Response regulator of the LytR AlgR family
GO992_13625	COG2223	nitrite transmembrane transporter activity
GO992_13630	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
GO992_13635	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
GO992_13650	COG0583	DNA-binding transcription factor activity
GO992_13655	COG4206	TonB-dependent receptor
GO992_13660	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
GO992_13690	COG0045	succinate-CoA ligase (ADP-forming) activity
GO992_13690	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GO992_13690	COG1042	CoA-binding domain protein
GO992_13705	COG0583	DNA-binding transcription factor activity
GO992_13710	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
GO992_13715	COG0166	Belongs to the GPI family
GO992_13725	COG0668	transmembrane transport
GO992_13730	COG1309	transcriptional regulator
GO992_13735	COG0756	dUTP diphosphatase activity
GO992_13740	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
GO992_13745	COG2003	Belongs to the UPF0758 family
GO992_13750	COG0227	Belongs to the bacterial ribosomal protein bL28 family
GO992_13755	COG0267	Belongs to the bacterial ribosomal protein bL33 family
GO992_13765	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
GO992_13770	COG2990	Protein conserved in bacteria
GO992_13775	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
GO992_13780	COG0859	PFAM glycosyl transferase family 9
GO992_13785	COG0463	Glycosyl transferase, family 2
GO992_13790	COG0859	PFAM glycosyl transferase family 9
GO992_13795	COG1519	Transferase
GO992_13810	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
GO992_13815	COG1609	Transcriptional regulator
GO992_13840	COG1580	Controls the rotational direction of flagella during chemotaxis
GO992_13845	COG3161	chorismate lyase activity
GO992_13850	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
GO992_13855	COG2937	Belongs to the GPAT DAPAT family
GO992_13860	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
GO992_13875	COG0534	Mate efflux family protein
GO992_13880	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
GO992_13885	COG2205	protein histidine kinase activity
GO992_13890	COG0745	RESPONSE REGULATOR receiver
GO992_13900	COG1045	serine acetyltransferase
GO992_13910	COG3074	FtsZ-dependent cytokinesis
GO992_13915	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
GO992_13925	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
GO992_13975	COG1609	Transcriptional regulator
GO992_13985	COG1262	PFAM Formylglycine-generating sulfatase enzyme
GO992_14005	COG0583	DNA-binding transcription factor activity
GO992_14030	COG0210	DNA helicase
GO992_14070	COG1280	lysine exporter protein (LysE YggA)
GO992_14075	COG2391	methyltransferase activity
GO992_14080	COG5433	transposase activity
GO992_14100	COG0518	GMP synthase (glutamine-hydrolyzing) activity
GO992_14100	COG0519	Catalyzes the synthesis of GMP from XMP
GO992_14105	COG0686	Belongs to the AlaDH PNT family
GO992_14110	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GO992_14130	COG1322	Protein conserved in bacteria
GO992_14135	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
GO992_14140	COG0569	domain protein
GO992_14145	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
GO992_14145	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
GO992_14150	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
GO992_14155	COG0242	peptide deformylase activity
GO992_14160	COG1652	LysM domain
GO992_14180	COG2922	Belongs to the Smg family
GO992_14185	COG0551	DNA topoisomerase type I activity
GO992_14195	COG0009	L-threonylcarbamoyladenylate synthase
GO992_14200	COG0408	coproporphyrinogen oxidase activity
GO992_14205	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
GO992_14220	COG0218	Necessary for normal cell division and for the maintenance of normal septation
GO992_14230	COG3078	GTPase activator activity
GO992_14240	COG0635	Involved in the biosynthesis of porphyrin-containing compound
GO992_14245	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
GO992_14250	COG2204	response regulator
GO992_14255	COG3852	Histidine kinase
GO992_14265	COG0174	glutamine synthetase
GO992_14275	COG1295	ribonuclease BN
GO992_14280	COG1490	D-aminoacyl-tRNA deacylase activity
GO992_14290	COG0456	acetyltransferase
GO992_14300	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
GO992_14305	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
GO992_14310	COG2610	gluconate transmembrane transporter activity
GO992_14315	COG3265	gluconokinase activity
GO992_14320	COG0129	dihydroxy-acid dehydratase activity
GO992_14325	COG0800	Aldolase
GO992_14330	COG1609	Transcriptional regulator
GO992_14340	COG4942	peptidase
GO992_14345	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
GO992_14350	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
GO992_14355	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
GO992_14360	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
GO992_14365	COG0316	Belongs to the HesB IscA family
GO992_14365	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
GO992_14370	COG1040	competence protein
GO992_14375	COG0596	Alpha beta hydrolase
GO992_14395	COG2183	response to ionizing radiation
GO992_14400	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
GO992_14405	COG0745	RESPONSE REGULATOR receiver
GO992_14420	COG0051	transcription antitermination factor activity, RNA binding
GO992_14425	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
GO992_14430	COG0088	Forms part of the polypeptide exit tunnel
GO992_14435	COG0089	rRNA binding
GO992_14440	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
GO992_14445	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
GO992_14450	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
GO992_14455	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
GO992_14460	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
GO992_14465	COG0255	Belongs to the universal ribosomal protein uL29 family
GO992_14470	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
GO992_14475	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
GO992_14480	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
GO992_14485	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
GO992_14490	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
GO992_14495	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
GO992_14500	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
GO992_14505	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
GO992_14510	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
GO992_14515	COG1841	ribosomal large subunit assembly
GO992_14520	COG0200	Binds to the 23S rRNA
GO992_14525	COG0201	protein transport
GO992_14530	COG0257	Belongs to the bacterial ribosomal protein bL36 family
GO992_14535	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
GO992_14540	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
GO992_14545	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
GO992_14550	COG0202	RNA polymerase activity
GO992_14555	COG0203	ribosomal protein L17
GO992_14595	COG2252	PERMEase
GO992_14600	COG2376	Dihydroxyacetone kinase
GO992_14605	COG1461	Dihydroxyacetone kinase
GO992_14610	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
GO992_14610	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
GO992_14610	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
GO992_14620	COG3284	Transcriptional regulator
GO992_14625	COG0628	permease
GO992_14635	COG5433	transposase activity
GO992_14650	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
GO992_14655	COG1288	antiporter activity
GO992_14665	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
GO992_14670	COG0540	Belongs to the ATCase OTCase family
GO992_14685	COG0688	phosphatidylethanolamine metabolic process
GO992_14695	COG3040	lipid binding
GO992_14705	COG1979	alcohol dehydrogenase
GO992_14710	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
GO992_14715	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
GO992_14725	COG2964	Protein conserved in bacteria
GO992_14730	COG3681	Belongs to the UPF0597 family
GO992_14740	COG0446	pyridine nucleotide-disulphide oxidoreductase
GO992_14745	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
GO992_14750	COG0564	pseudouridine synthase activity
GO992_14760	COG0542	response to heat
GO992_14765	COG2502	aspartate--ammonia ligase
GO992_14770	COG1522	sequence-specific DNA binding
GO992_14780	COG5413	integral membrane protein
GO992_14785	COG0517	IMP dehydrogenase activity
GO992_14785	COG0516	GMP reductase activity
GO992_14790	COG1028	Short-chain dehydrogenase reductase Sdr
GO992_14805	COG2205	protein histidine kinase activity
GO992_14815	COG2204	response regulator
GO992_14830	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
GO992_14850	COG0745	RESPONSE REGULATOR receiver
GO992_14855	COG2205	protein histidine kinase activity
GO992_14865	COG0243	molybdopterin cofactor binding
GO992_14870	COG3005	denitrification pathway
GO992_14875	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
GO992_14880	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
GO992_14885	COG0569	domain protein
GO992_14890	COG0812	UDP-N-acetylmuramate dehydrogenase activity
GO992_14915	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
GO992_14925	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
GO992_14930	COG0250	Participates in transcription elongation, termination and antitermination
GO992_14935	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
GO992_14940	COG0081	regulation of translation
GO992_14945	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
GO992_14950	COG0222	ribosome binding
GO992_14955	COG0085	RNA polymerase activity
GO992_14960	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
GO992_14965	COG2964	Protein conserved in bacteria
GO992_14970	COG0251	oxidation-reduction process
GO992_14980	COG2923	Belongs to the DsrF TusC family
GO992_14985	COG2168	tRNA wobble position uridine thiolation
GO992_14990	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
GO992_14995	COG0049	tRNA binding
GO992_15000	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
GO992_15005	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
GO992_15010	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
GO992_15070	COG3047	cAMP biosynthetic process
GO992_15100	COG3135	benzoate transporter
GO992_15105	COG1396	sequence-specific DNA binding
GO992_15135	COG2926	Belongs to the UPF0265 family
GO992_15145	COG3028	Belongs to the UPF0307 family
GO992_15150	COG0312	modulator of DNA gyrase
GO992_15155	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
GO992_15160	COG5007	Belongs to the BolA IbaG family
GO992_15170	COG2854	intermembrane phospholipid transfer
GO992_15175	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
GO992_15180	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
GO992_15185	COG1127	ABC transporter
GO992_15190	COG0517	IMP dehydrogenase activity
GO992_15190	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
GO992_15195	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
GO992_15200	COG3117	lipopolysaccharide transmembrane transporter activity
GO992_15205	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
GO992_15210	COG1137	ATPase activity
GO992_15215	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
GO992_15225	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
GO992_15230	COG1660	Displays ATPase and GTPase activities
GO992_15235	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
GO992_15255	COG3964	amidohydrolase
GO992_15290	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GO992_15295	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GO992_15305	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
GO992_15310	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
GO992_15315	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO992_15320	COG0723	plastoquinol--plastocyanin reductase activity
GO992_15325	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
GO992_15330	COG2857	Cytochrome c1
GO992_15335	COG0625	glutathione transferase activity
GO992_15340	COG2969	positive regulation of protein catabolic process
GO992_15345	COG2823	Periplasmic or secreted lipoprotein
GO992_15350	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
GO992_15360	COG3107	peptidoglycan biosynthetic process
GO992_15365	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
GO992_15390	COG1987	bacterial-type flagellum assembly
GO992_15410	COG2204	response regulator
GO992_15415	COG1677	Flagellar hook-basal body complex protein FliE
GO992_15425	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
GO992_15455	COG2747	anti-sigma28 factor FlgM
GO992_15465	COG1815	bacterial-type flagellum-dependent cell motility
GO992_15470	COG1558	bacterial-type flagellum-dependent cell motility
GO992_15475	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
GO992_15485	COG4786	Flagellar basal body rod
GO992_15490	COG4786	Flagellar basal body rod
GO992_15495	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
GO992_15500	COG1706	bacterial-type flagellum-dependent cell motility
GO992_15510	COG4786	Flagellar basal body rod
GO992_15510	COG1256	bacterial-type flagellum assembly
GO992_15540	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
GO992_15545	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
GO992_15570	COG1191	sigma factor activity
GO992_15575	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
GO992_15580	COG1360	Flagellar Motor Protein
GO992_15585	COG0741	lytic transglycosylase activity
GO992_15585	COG1388	LysM domain
GO992_15595	COG2001	Belongs to the MraZ family
GO992_15600	COG0275	rRNA processing
GO992_15605	COG3116	cell division
GO992_15610	COG0768	penicillin binding
GO992_15620	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
GO992_15630	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
GO992_15635	COG0772	Belongs to the SEDS family
GO992_15640	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
GO992_15645	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
GO992_15650	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
GO992_15655	COG0849	cell division
GO992_15660	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
GO992_15665	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
GO992_15675	COG0653	protein targeting
GO992_15685	COG0494	nUDIX hydrolase
GO992_15690	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
GO992_15695	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
GO992_15705	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
GO992_15715	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
GO992_15740	COG2186	Transcriptional regulator
GO992_15745	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
GO992_15750	COG0508	dehydrogenase complex catalyzes the overall conversion of
GO992_15755	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
GO992_15760	COG5002	protein histidine kinase activity
GO992_15760	COG3447	MASE1 domain protein
GO992_15760	COG5001	Diguanylate cyclase
GO992_15770	COG0840	transmembrane signaling receptor activity
GO992_15775	COG0840	transmembrane signaling receptor activity
GO992_15785	COG1049	propionate catabolic process, 2-methylcitrate cycle
GO992_15795	COG5433	transposase activity
GO992_15815	COG1028	Short-chain dehydrogenase reductase Sdr
GO992_15820	COG0583	DNA-binding transcription factor activity
GO992_15830	COG1280	lysine exporter protein (LysE YggA)
GO992_15840	COG0523	cobalamin synthesis protein
GO992_15870	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
GO992_15875	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
GO992_15970	COG0189	ligase activity
GO992_15980	COG0745	RESPONSE REGULATOR receiver
GO992_16015	COG1639	'signal transduction protein
GO992_16025	COG3700	Belongs to the class B bacterial acid phosphatase family
GO992_16035	COG1366	Belongs to the anti-sigma-factor antagonist family
GO992_16040	COG2172	sigma factor antagonist activity
GO992_16045	COG0784	Response regulator, receiver
GO992_16045	COG2205	protein histidine kinase activity
GO992_16045	COG5002	protein histidine kinase activity
GO992_16050	COG3437	response regulator, receiver
GO992_16060	COG0477	Major facilitator Superfamily
GO992_16075	COG0312	modulator of DNA gyrase
GO992_16080	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
GO992_16090	COG3164	Protein of unknown function
GO992_16095	COG1530	ribonuclease E activity
GO992_16100	COG0424	maF-like protein
GO992_16105	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
GO992_16110	COG1792	Involved in formation and maintenance of cell shape
GO992_16115	COG1077	Cell shape determining protein MreB Mrl
GO992_16170	COG2199	diguanylate cyclase activity
GO992_16170	COG2200	EAL domain
GO992_16180	COG0387	Pfam Sodium calcium exchanger
GO992_16185	COG2986	histidine ammonia-lyase
GO992_16190	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
GO992_16195	COG0010	Belongs to the arginase family
GO992_16200	COG1228	amidohydrolase
GO992_16205	COG2188	Transcriptional regulator
GO992_16210	COG0288	reversible hydration of carbon dioxide
GO992_16220	COG2177	Part of the ABC transporter FtsEX involved in
GO992_16225	COG2884	Cell division ATP-binding protein ftsE
GO992_16230	COG0552	protein localization to endoplasmic reticulum
GO992_16235	COG0742	ribosomal rna small subunit methyltransferase
GO992_16265	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
GO992_16270	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
GO992_16280	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
GO992_16290	COG2095	MarC family integral membrane protein
GO992_16300	COG1301	dicarboxylic acid transport
GO992_16325	COG3714	YhhN family
GO992_16350	COG1770	oligopeptidase
GO992_16365	COG2249	NAD(P)H dehydrogenase (quinone) activity
GO992_16425	COG0513	Belongs to the DEAD box helicase family
GO992_16445	COG1912	Pfam S-adenosyl-l-methionine hydroxide adenosyltransferase
GO992_16510	COG2816	NAD+ diphosphatase activity
GO992_16515	COG2205	protein histidine kinase activity
GO992_16520	COG0745	RESPONSE REGULATOR receiver
GO992_16525	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GO992_16545	COG2982	Protein involved in outer membrane biogenesis
GO992_16555	COG1028	Short-chain dehydrogenase reductase Sdr
GO992_16560	COG5433	transposase activity
GO992_16575	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
GO992_16600	COG5433	transposase activity
GO992_16605	COG1028	Short-chain dehydrogenase reductase Sdr
GO992_16620	COG1349	DNA-binding transcription factor activity
GO992_16625	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
GO992_16655	COG2130	NADP-dependent
GO992_16660	COG1764	response to oxidative stress
GO992_16665	COG1846	Transcriptional regulator
GO992_16695	COG0561	phosphatase activity
GO992_16710	COG0733	neurotransmitter:sodium symporter activity
GO992_16720	COG0733	neurotransmitter:sodium symporter activity
GO992_16745	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GO992_16760	COG1794	racemase activity, acting on amino acids and derivatives
GO992_16770	COG2731	YhcH YjgK YiaL family protein
GO992_16780	COG0668	transmembrane transport
GO992_16785	COG1376	ErfK ybiS ycfS ynhG family protein
GO992_16790	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GO992_16800	COG0789	Transcriptional regulator
GO992_16805	COG5433	transposase activity
GO992_16820	COG5433	transposase activity
GO992_16880	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
GO992_16890	COG0488	(ABC) transporter
GO992_16895	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
GO992_16895	COG0517	IMP dehydrogenase activity
GO992_16900	COG1585	Membrane protein implicated in regulation of membrane protease activity
GO992_16905	COG0330	HflC and HflK could
GO992_16915	COG0175	sulfate reduction
GO992_16920	COG2895	sulfate adenylyltransferase (ATP) activity
GO992_16925	COG0471	metal ion transport
GO992_16925	COG3273	potassium ion transport
GO992_16930	COG0529	Catalyzes the synthesis of activated sulfate
GO992_16950	COG3328	transposase activity
GO992_16955	COG5433	transposase activity
GO992_16985	COG0840	transmembrane signaling receptor activity
GO992_17020	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
GO992_17040	COG1940	carbohydrate kinase activity
GO992_17045	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
GO992_17050	COG0126	phosphoglycerate kinase activity
GO992_17055	COG0191	fructose-bisphosphate aldolase activity
GO992_17060	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
GO992_17110	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
GO992_17115	COG1595	DNA-templated transcription, initiation
GO992_17120	COG3073	An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E
GO992_17135	COG0481	GTPase activity
GO992_17140	COG0681	Belongs to the peptidase S26 family
GO992_17145	COG0571	ribonuclease III activity
GO992_17155	COG1381	Involved in DNA repair and RecF pathway recombination
GO992_17160	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
GO992_17165	COG3023	N-Acetylmuramoyl-L-alanine amidase
GO992_17170	COG4807	Protein conserved in bacteria
GO992_17180	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
GO992_17185	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
GO992_17190	COG3956	TIGRFAM MazG family protein
GO992_17195	COG0504	CTP synthase activity
GO992_17200	COG0148	phosphopyruvate hydratase activity
GO992_17205	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
GO992_17210	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
GO992_17220	COG0585	pseudouridine synthase activity
GO992_17225	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
GO992_17230	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
GO992_17235	COG1238	metal cluster binding
GO992_17240	COG1388	LysM domain
GO992_17240	COG4942	peptidase
GO992_17250	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
GO992_17255	COG0828	Belongs to the bacterial ribosomal protein bS21 family
GO992_17260	COG1610	YqeY-like protein
GO992_17265	COG0358	DNA primase activity
GO992_17270	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
GO992_17310	COG0151	Belongs to the GarS family
GO992_17315	COG0138	bifunctional purine biosynthesis protein purh
GO992_17325	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
GO992_17330	COG3036	rescue of stalled ribosome
GO992_17335	COG0635	Involved in the biosynthesis of porphyrin-containing compound
GO992_17340	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
GO992_17350	COG0673	inositol 2-dehydrogenase activity
GO992_17365	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GO992_17370	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GO992_17375	COG3227	Zinc metalloprotease (Elastase)
GO992_17385	COG0477	Major facilitator Superfamily
GO992_17395	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
GO992_17400	COG1027	Aspartate ammonia-lyase
GO992_17405	COG3030	protein affecting phage T7 exclusion by the F plasmid
GO992_17415	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
GO992_17420	COG0459	protein refolding
GO992_17430	COG3300	MHYT domain
GO992_17430	COG5001	Diguanylate cyclase
GO992_17440	COG0564	pseudouridine synthase activity
GO992_17445	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
GO992_17470	COG1280	lysine exporter protein (LysE YggA)
GO992_17475	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
GO992_17490	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GO992_17520	COG0745	RESPONSE REGULATOR receiver
GO992_17525	COG3104	oligopeptide transport
GO992_17530	COG1210	Utp--glucose-1-phosphate uridylyltransferase
GO992_17535	COG1555	photosystem II stabilization
GO992_17545	COG2350	Protein conserved in bacteria
GO992_17550	COG2917	probably involved in intracellular septation
GO992_17555	COG0076	glutamate decarboxylase activity
GO992_17560	COG1272	protein, Hemolysin III
GO992_17565	COG0569	domain protein
GO992_17565	COG2985	domain, Protein
GO992_17575	COG0784	Response regulator, receiver
GO992_17575	COG0835	chemotaxis
GO992_17580	COG2755	lipolytic protein G-D-S-L family
GO992_17585	COG4181	ATPase activity
GO992_17590	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
GO992_17600	COG2200	EAL domain
GO992_17605	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GO992_17610	COG4935	Belongs to the peptidase S8 family
GO992_17610	COG2234	aminopeptidase activity
GO992_17615	COG0220	tRNA (guanine-N7-)-methyltransferase activity
GO992_17620	COG3171	Protein conserved in bacteria
GO992_17630	COG2897	thiosulfate sulfurtransferase activity
GO992_17640	COG1132	(ABC) transporter
GO992_17650	COG1012	belongs to the aldehyde dehydrogenase family
GO992_17680	COG3291	Pkd domain containing protein
GO992_17680	COG4412	M6 family metalloprotease domain protein
GO992_17685	COG3076	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome
GO992_17690	COG3300	MHYT domain
GO992_17690	COG5001	Diguanylate cyclase
GO992_17710	COG4628	conserved protein (DUF2132)
GO992_17715	COG0688	phosphatidylethanolamine metabolic process
GO992_17725	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
GO992_17755	COG1278	Cold shock
GO992_17770	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
GO992_17825	COG0848	biopolymer transport protein
GO992_17830	COG0811	peptide transport
GO992_17835	COG0811	peptide transport
GO992_17845	COG4206	TonB-dependent receptor
GO992_17865	COG4239	(ABC) transporter, permease
GO992_17875	COG0444	Belongs to the ABC transporter superfamily
GO992_17880	COG4608	Belongs to the ABC transporter superfamily
GO992_17890	COG2195	Cleaves the N-terminal amino acid of tripeptides
GO992_17905	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
GO992_17920	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
GO992_17925	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
GO992_17955	COG1522	sequence-specific DNA binding
GO992_17955	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GO992_17975	COG1858	cytochrome C peroxidase
GO992_18015	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
GO992_18020	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
GO992_18030	COG0318	PFAM AMP-dependent synthetase and ligase
GO992_18035	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
GO992_18045	COG2986	histidine ammonia-lyase
GO992_18070	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
GO992_18080	COG1028	Short-chain dehydrogenase reductase Sdr
GO992_18085	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
GO992_18095	COG0521	Mo-molybdopterin cofactor biosynthetic process
GO992_18110	COG5433	transposase activity
GO992_18120	COG2966	Psort location CytoplasmicMembrane, score
GO992_18125	COG3610	response to peptide
GO992_18135	COG4175	Glycine betaine
GO992_18140	COG4176	ABC-type proline glycine betaine transport system permease component
GO992_18145	COG2113	Glycine betaine
GO992_18150	COG0175	sulfate reduction
GO992_18155	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
GO992_18160	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
GO992_18165	COG0384	phenazine biosynthesis protein PhzF
GO992_18170	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
GO992_18185	COG0786	glutamate:sodium symporter activity
GO992_18190	COG0252	asparaginase activity
GO992_18195	COG3139	Protein of unknown function (DUF1315)
GO992_18215	COG0616	signal peptide processing
GO992_18220	COG0446	pyridine nucleotide-disulphide oxidoreductase
GO992_18220	COG1902	pentaerythritol trinitrate reductase activity
GO992_18225	COG0778	Nitroreductase
GO992_18245	COG4302	ethanolamine ammonia-lyase activity
GO992_18250	COG4303	Ethanolamine ammonia lyase large subunit
GO992_18255	COG0531	amino acid
GO992_18260	COG2264	protein methyltransferase activity
GO992_18265	COG0604	alcohol dehydrogenase
GO992_18275	COG0583	DNA-binding transcription factor activity
GO992_18280	COG1263	PTS System
GO992_18280	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GO992_18280	COG2190	(PTS) system
GO992_18285	COG4145	pantothenate transmembrane transporter activity
GO992_18290	COG3924	membrane
GO992_18295	COG0439	Biotin carboxylase
GO992_18300	COG0511	ligase activity, forming carbon-carbon bonds
GO992_18305	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
GO992_18310	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
GO992_18340	COG3381	protein complex oligomerization
GO992_18350	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
GO992_18365	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
GO992_18370	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
GO992_18370	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
GO992_18385	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
GO992_18390	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
GO992_18395	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
GO992_18400	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
GO992_18425	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
GO992_18430	COG0142	geranyltranstransferase activity
GO992_18435	COG1722	exodeoxyribonuclease VII activity
GO992_18440	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
GO992_18445	COG1360	Flagellar Motor Protein
GO992_18455	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
GO992_18465	COG1534	Rna-binding protein
GO992_18470	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
GO992_18475	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
GO992_18480	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
GO992_18485	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
GO992_18490	COG0149	triose-phosphate isomerase activity
GO992_18495	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
GO992_18510	COG0779	Required for maturation of 30S ribosomal subunits
GO992_18515	COG0195	Participates in both transcription termination and antitermination
GO992_18520	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
GO992_18525	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
GO992_18530	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
GO992_18535	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
GO992_18540	COG1185	polyribonucleotide nucleotidyltransferase activity
GO992_18545	COG2211	Major facilitator Superfamily
GO992_18550	COG3706	GGDEF domain
GO992_18555	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
GO992_18560	COG1422	Protein of unknown function (DUF1090)
GO992_18630	COG0312	modulator of DNA gyrase
GO992_18640	COG0716	FMN binding
GO992_18645	COG4974	Belongs to the 'phage' integrase family
GO992_18660	COG1970	mechanosensitive ion channel activity
GO992_18665	COG5433	transposase activity
GO992_18675	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
GO992_18690	COG3545	Serine hydrolase
GO992_18695	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GO992_18760	COG5433	transposase activity
GO992_18785	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
GO992_18790	COG0321	lipoyl(octanoyl) transferase activity
GO992_18795	COG2921	Belongs to the UPF0250 family
GO992_18800	COG1686	Belongs to the peptidase S11 family
GO992_18805	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
GO992_18810	COG2951	lytic endotransglycosylase activity
GO992_18815	COG0772	Belongs to the SEDS family
GO992_18820	COG0768	penicillin binding
GO992_18825	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
GO992_18830	COG0799	negative regulation of ribosome biogenesis
GO992_18835	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
GO992_18855	COG0495	leucyl-tRNA aminoacylation
GO992_18860	COG2888	peptidyl-tyrosine sulfation
GO992_18865	COG0815	Transfers the fatty acyl group on membrane lipoproteins
GO992_18870	COG4535	Mg2 and Co2 transporter CorC
GO992_18875	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
GO992_18880	COG1702	phosphate starvation-inducible protein PhoH
GO992_18885	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
GO992_18890	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
GO992_18900	COG3706	GGDEF domain
GO992_18915	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
GO992_18935	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
GO992_18945	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
GO992_18955	COG0516	GMP reductase activity
GO992_18965	COG0642	Histidine kinase
GO992_18970	COG0745	RESPONSE REGULATOR receiver
GO992_19005	COG3214	Protein conserved in bacteria
GO992_19025	COG3080	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
GO992_19030	COG3029	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
GO992_19035	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
GO992_19040	COG1053	succinate dehydrogenase
GO992_19050	COG0584	glycerophosphoryl diester phosphodiesterase
GO992_19055	COG1511	domain protein
GO992_19055	COG3264	Mechanosensitive ion channel
GO992_19070	COG0739	heme binding
GO992_19085	COG0583	DNA-binding transcription factor activity
GO992_19100	COG0840	transmembrane signaling receptor activity
GO992_19105	COG0583	DNA-binding transcription factor activity
GO992_19110	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
GO992_19140	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
GO992_19145	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
GO992_19155	COG0338	D12 class N6 adenine-specific DNA methyltransferase
GO992_19160	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
GO992_19165	COG0546	phosphoglycolate phosphatase activity
GO992_19170	COG0180	Tryptophanyl-tRNA synthetase
GO992_19185	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
GO992_19195	COG1012	belongs to the aldehyde dehydrogenase family
GO992_19205	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
GO992_19235	COG3089	Belongs to the UPF0270 family
GO992_19255	COG0429	hydrolase of the alpha beta-hydrolase fold
GO992_19260	COG0835	chemotaxis
GO992_19260	COG0784	Response regulator, receiver
GO992_19270	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
GO992_19275	COG1047	Peptidyl-prolyl cis-trans
GO992_19280	COG2900	Belongs to the SlyX family
GO992_19290	COG0545	Peptidyl-prolyl cis-trans isomerase
GO992_19295	COG2204	response regulator
GO992_19315	COG0737	Belongs to the 5'-nucleotidase family
GO992_19320	COG2200	EAL domain
GO992_19335	COG0305	Participates in initiation and elongation during chromosome replication
GO992_19340	COG0305	Participates in initiation and elongation during chromosome replication
GO992_19345	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
GO992_19350	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
GO992_19360	COG2200	EAL domain
GO992_19360	COG2203	Gaf domain
GO992_19360	COG2199	diguanylate cyclase activity
GO992_19365	COG5433	transposase activity
GO992_19380	COG5433	transposase activity
GO992_19410	COG0300	oxidoreductase activity
GO992_19435	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
GO992_19450	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
GO992_19460	COG3813	Protein conserved in bacteria
GO992_19475	COG1280	lysine exporter protein (LysE YggA)
GO992_19485	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
GO992_19490	COG0840	transmembrane signaling receptor activity
GO992_19505	COG2198	Histidine kinase
GO992_19505	COG0643	Histidine kinase
GO992_19515	COG0835	chemotaxis
GO992_19520	COG0840	transmembrane signaling receptor activity
GO992_19540	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
GO992_19545	COG2201	protein-glutamate methylesterase activity
GO992_19550	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
GO992_19600	COG2133	pyrroloquinoline quinone binding
GO992_19625	COG1605	Chorismate mutase
GO992_19625	COG0077	Prephenate dehydratase
GO992_19655	COG3272	Protein of unknown function (DUF1722)
GO992_19660	COG0789	Transcriptional regulator
GO992_19665	COG0415	Belongs to the DNA photolyase family
GO992_19675	COG0300	oxidoreductase activity
GO992_19690	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
GO992_19715	COG0783	Belongs to the Dps family
GO992_19720	COG1151	hydroxylamine reductase activity
GO992_19730	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
GO992_19735	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
GO992_19735	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
GO992_19750	COG3459	Glycosyltransferase 36 associated
GO992_19775	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
GO992_19780	COG1666	GTP binding
GO992_19785	COG3248	Nucleoside-binding outer membrane protein
GO992_19790	COG2211	Major facilitator Superfamily
GO992_19800	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
GO992_19810	COG2813	Specifically methylates the guanine in position
GO992_19815	COG0271	Belongs to the BolA IbaG family
GO992_19825	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
GO992_19830	COG1805	sodium ion transport
GO992_19835	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
GO992_19840	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
GO992_19845	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
GO992_19850	COG2871	sodium ion transport
GO992_19855	COG1477	protein flavinylation
GO992_19870	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
GO992_19875	COG0840	transmembrane signaling receptor activity
GO992_19880	COG0583	DNA-binding transcription factor activity
GO992_19890	COG2363	Small membrane protein
GO992_19895	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
GO992_19905	COG0473	3-isopropylmalate dehydrogenase activity
GO992_19910	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
GO992_19915	COG1611	Belongs to the LOG family
GO992_19920	COG3706	GGDEF domain
GO992_19930	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
GO992_19930	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
GO992_19940	COG5595	Zn-ribbon-containing, possibly nucleic-acid-binding protein (DUF2310)
GO992_19965	COG3098	single-species biofilm formation
GO992_19970	COG0564	pseudouridine synthase activity
GO992_19980	COG4580	involved in the transport of maltose and maltodextrins
GO992_19990	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GO992_19990	COG1263	PTS System
GO992_20000	COG2171	N-acyltransferase activity
GO992_20005	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
GO992_20010	COG0024	Methionine aminopeptidase
GO992_20015	COG0052	Belongs to the universal ribosomal protein uS2 family
GO992_20020	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
GO992_20025	COG0528	UMP kinase activity
GO992_20030	COG0233	cytoplasmic translational termination
GO992_20035	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
GO992_20040	COG0575	Belongs to the CDS family
GO992_20045	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
GO992_20050	COG0750	zinc metalloprotease
GO992_20065	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
GO992_20070	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
GO992_20075	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
GO992_20080	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
GO992_20085	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
GO992_20095	COG0825	malonyl-CoA metabolic process
GO992_20100	COG3710	Transcriptional regulator
GO992_20105	COG0531	amino acid
GO992_20110	COG1982	Orn Lys Arg decarboxylase major
GO992_20115	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
GO992_20130	COG0814	amino acid
GO992_20135	COG0531	amino acid
GO992_20145	COG0488	(ABC) transporter
GO992_20155	COG3590	peptidase
GO992_20160	COG0037	tRNA processing
GO992_20165	COG3706	GGDEF domain
GO992_20220	COG0366	Alpha amylase catalytic
GO992_20240	COG0583	DNA-binding transcription factor activity
GO992_20250	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
GO992_20260	COG0583	DNA-binding transcription factor activity
GO992_20265	COG1028	Short-chain dehydrogenase reductase Sdr
GO992_20270	COG0616	signal peptide processing
GO992_20275	COG3724	N-succinylarginine dihydrolase activity
GO992_20280	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
GO992_20290	COG0840	transmembrane signaling receptor activity
GO992_20300	COG2971	BadF BadG BcrA BcrD
GO992_20310	COG4608	Belongs to the ABC transporter superfamily
GO992_20315	COG0444	Belongs to the ABC transporter superfamily
GO992_20320	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GO992_20370	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
GO992_20375	COG1289	transmembrane transporter activity
GO992_20380	COG0303	'Molybdopterin
GO992_20385	COG0746	molybdenum cofactor guanylyltransferase activity
GO992_20395	COG4662	Binding-protein-dependent transport system inner membrane component
GO992_20410	COG3852	Histidine kinase
GO992_20420	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
GO992_20425	COG3328	transposase activity
GO992_20470	COG0582	viral genome integration into host DNA
GO992_20480	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
GO992_20490	COG2867	negative regulation of translational initiation
GO992_20500	COG0702	epimerase
GO992_20505	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
GO992_20535	COG4964	Belongs to the GSP D family
GO992_20545	COG2894	cell division
GO992_20585	COG1454	alcohol dehydrogenase
GO992_20600	COG1957	nucleoside hydrolase
GO992_20620	COG0840	transmembrane signaling receptor activity
GO992_20625	COG1280	lysine exporter protein (LysE YggA)
GO992_20660	COG3263	regulation of cellular component size
GO992_20670	COG1876	peptidase activity
GO992_20675	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
GO992_20680	COG1393	Belongs to the ArsC family
GO992_20685	COG0583	DNA-binding transcription factor activity
GO992_20700	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
GO992_20705	COG0017	Asparaginyl-tRNA synthetase
GO992_20725	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
GO992_20730	COG0156	8-amino-7-oxononanoate synthase activity
GO992_20735	COG1073	alpha beta
GO992_20735	COG2226	methyltransferase
GO992_20740	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
GO992_20745	COG0501	Belongs to the peptidase M48B family
GO992_20755	COG0633	Ferredoxin
GO992_20755	COG3217	Mosc domain protein beta barrel domain protein
GO992_20755	COG3217	Mosc domain protein beta barrel domain protein
GO992_20755	COG0633	Ferredoxin
GO992_20780	COG2841	Protein conserved in bacteria
GO992_20790	COG0534	Mate efflux family protein
GO992_20830	COG1309	transcriptional regulator
GO992_20845	COG0791	NLP P60 protein
GO992_20860	COG0583	DNA-binding transcription factor activity
GO992_20870	COG0643	Histidine kinase
GO992_20870	COG2198	Histidine kinase
GO992_20875	COG2201	protein-glutamate methylesterase activity
GO992_20880	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
GO992_20885	COG1360	Flagellar Motor Protein
GO992_20890	COG1192	Involved in chromosome partitioning
GO992_20900	COG0835	chemotaxis
GO992_20920	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
GO992_20925	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
GO992_20930	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
GO992_20935	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
GO992_20940	COG1138	Cytochrome C-type biogenesis protein
GO992_20945	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GO992_20950	COG3088	subunit of a heme lyase
GO992_20950	COG4235	cytochrome complex assembly
GO992_20970	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
GO992_20975	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
GO992_20975	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
GO992_20990	COG0259	pyridoxamine-phosphate oxidase activity
GO992_21005	COG3153	acetyltransferase
GO992_21025	COG2850	peptidyl-arginine hydroxylation
GO992_21030	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
GO992_21035	COG2915	High frequency lysogenization protein hflD homolog
GO992_21040	COG0482	sulfurtransferase activity
GO992_21060	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GO992_21135	COG2119	membrane
GO992_21140	COG0023	Translation Initiation Factor
GO992_21190	COG2205	protein histidine kinase activity
GO992_21190	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GO992_21200	COG4138	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system
GO992_21205	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
GO992_21210	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
GO992_21215	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
GO992_21220	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
GO992_21225	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
GO992_21240	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
GO992_21245	COG0505	Belongs to the CarA family
GO992_21250	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
GO992_21255	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
GO992_21295	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GO992_21300	COG0513	Belongs to the DEAD box helicase family
GO992_21330	COG0789	Transcriptional regulator
GO992_21345	COG0493	'glutamate synthase
GO992_21350	COG0067	glutamate synthase
GO992_21350	COG0069	glutamate synthase activity
GO992_21350	COG0070	glutamate synthase
GO992_21355	COG1242	4 iron, 4 sulfur cluster binding
GO992_21395	COG5433	transposase activity
GO992_21430	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
GO992_21435	COG1288	antiporter activity
GO992_21450	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
GO992_21455	COG2027	D-alanyl-D-alanine carboxypeptidase
GO992_21460	COG1061	Type III restriction enzyme res subunit
GO992_21465	COG1566	PFAM secretion protein HlyD family protein
GO992_21475	COG1966	Carbon starvation protein
GO992_21480	COG3279	Response regulator of the LytR AlgR family
GO992_21485	COG3275	phosphorelay sensor kinase activity
GO992_21505	COG1012	belongs to the aldehyde dehydrogenase family
GO992_21505	COG1454	alcohol dehydrogenase
GO992_21515	COG2095	MarC family integral membrane protein
GO992_21525	COG0601	transmembrane transport
GO992_21530	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GO992_21535	COG0444	Belongs to the ABC transporter superfamily
GO992_21550	COG0861	Integral membrane protein TerC family
GO992_21565	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
GO992_21575	COG1301	dicarboxylic acid transport
GO992_21590	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
GO992_21605	COG0537	adenosine 5'-monophosphoramidase activity
GO992_21640	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
GO992_21645	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
GO992_21680	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
GO992_21685	COG1360	Flagellar Motor Protein
GO992_21705	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
GO992_21720	COG4597	amino acid ABC transporter
GO992_21725	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GO992_21730	COG0765	amino acid transport
GO992_21755	COG0516	GMP reductase activity
GO992_21755	COG0517	IMP dehydrogenase activity
GO992_21760	COG0519	Catalyzes the synthesis of GMP from XMP
GO992_21760	COG0518	GMP synthase (glutamine-hydrolyzing) activity
GO992_21780	COG5433	transposase activity
GO992_21800	COG1025	Belongs to the peptidase M16 family
GO992_21805	COG2062	phosphohistidine phosphatase, SixA
GO992_21815	COG0697	spore germination
GO992_21820	COG4166	transmembrane transport
GO992_21825	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
GO992_21830	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
GO992_21840	COG4591	ABC-type transport system involved in lipoprotein release permease component
GO992_21845	COG1136	(ABC) transporter
GO992_21850	COG4591	ABC-type transport system involved in lipoprotein release permease component
GO992_21865	COG0544	peptidyl-prolyl cis-trans isomerase activity
GO992_21870	COG0740	serine-type endopeptidase activity
GO992_21875	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
GO992_21880	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
GO992_21885	COG0776	regulation of translation
GO992_21890	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
GO992_21895	COG0488	(ABC) transporter
GO992_21900	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GO992_21905	COG3162	membrane
GO992_21930	COG1024	Enoyl-CoA hydratase
GO992_21930	COG1250	3-hydroxyacyl-CoA dehydrogenase
GO992_21935	COG1115	amino acid carrier protein
GO992_21940	COG0456	acetyltransferase
GO992_21950	COG1584	GPR1 FUN34 yaaH family protein
GO992_21995	COG2062	phosphohistidine phosphatase, SixA
GO992_22045	COG2916	Histone family protein nucleoid-structuring protein H-NS
GO992_22055	COG1192	Involved in chromosome partitioning
GO992_22065	COG3328	transposase activity
GO992_22110	COG1317	bacterial-type flagellum organization
GO992_22200	COG0457	Tetratricopeptide repeat
GO992_22270	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
GO992_22275	COG4790	Type iii secretion
GO992_22280	COG4794	Type iii secretion
GO992_22285	COG4791	protein targeting
GO992_22290	COG4792	protein secretion
GO992_22330	COG1192	Involved in chromosome partitioning
GO992_22405	COG2336	PFAM SpoVT AbrB
GO992_22465	COG1484	DNA-dependent DNA replication
GO992_22520	COG2916	Histone family protein nucleoid-structuring protein H-NS
GO992_22530	COG1192	Involved in chromosome partitioning
GO992_22540	COG3328	transposase activity
GO992_22585	COG2916	Histone family protein nucleoid-structuring protein H-NS
GO992_22595	COG1192	Involved in chromosome partitioning
GO992_22605	COG3328	transposase activity