locus-tag	class	description
E3D14_00005	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
E3D14_00010	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
E3D14_00015	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
E3D14_00020	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
E3D14_00035	ENOG4105D29	Helix-turn-helix type 11 domain protein
E3D14_00040	ENOG4108ZNX	Heat shock protein
E3D14_00045	ENOG4108ZNX	Heat shock protein
E3D14_00060	ENOG4105JKW	Valine--pyruvate aminotransferase
E3D14_00085	ENOG4105EEX	Two component transcriptional regulator (Winged helix family
E3D14_00090	ENOG4105C08	Histidine kinase
E3D14_00100	ENOG4105C8X	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity)
E3D14_00105	ENOG4105D9K	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity)
E3D14_00115	ENOG4105DC8	reductase
E3D14_00120	ENOG4105BZU	Histidine kinase
E3D14_00125	ENOG4105BZS	acriflavin resistance protein
E3D14_00130	ENOG410624X	efflux transporter, rnd family, mfp subunit
E3D14_00135	ENOG4105EJ2	Transcriptional regulator
E3D14_00165	ENOG4105DQF	Hydrolase
E3D14_00170	ENOG4108EUD	Lysophospholipase
E3D14_00175	ENOG4105FE8	tRNA (Guanosine-2'-O-)-methyltransferase
E3D14_00180	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
E3D14_00185	ENOG4105VFG	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity)
E3D14_00190	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
E3D14_00200	ENOG4105DKP	glycosyl transferase, family 9
E3D14_00205	ENOG4108W7E	Catalyzes the ATP-dependent phosphorylation of the 3- deoxy-D-manno-octulosonic acid (Kdo) residue in Kdo-lipid IV(A) at the 4-OH position (By similarity)
E3D14_00215	ENOG4105EMK	carboxylate amino acid amine transporter
E3D14_00245	ENOG4108M6U	Universal stress protein A
E3D14_00250	ENOG4105RKW	reductase (By
E3D14_00260	ENOG41090A1	ferritin
E3D14_00265	ENOG4105CBX	hi0933 family
E3D14_00305	ENOG4105D70	Integrase catalytic subunit
E3D14_00310	ENOG4105F5W	AtP-binding protein
E3D14_00320	ENOG4108GWT	fimbrillin MatB
E3D14_00325	ENOG4108WQH	regulatoR
E3D14_00330	ENOG4105BZU	Histidine kinase
E3D14_00340	ENOG4105BZU	Histidine kinase
E3D14_00350	ENOG4108HRK	Histidine kinase
E3D14_00355	ENOG4105DY9	regulatoR
E3D14_00360	ENOG4105FCD	Major Facilitator
E3D14_00365	ENOG4105CY8	phosphoribosylaminoimidazole carboxylase atpase subunit
E3D14_00370	ENOG4108UM6	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity)
E3D14_00385	ENOG41063Z6	transcriptional regulator, lysR family
E3D14_00390	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
E3D14_00395	ENOG4105F03	Provides the (R)-glutamate required for cell wall biosynthesis (By similarity)
E3D14_00425	ENOG4105CD5	CoA-binding domain protein
E3D14_00440	ENOG4105EMY	transcriptional regulator
E3D14_00445	ENOG4105C6M	Alpha-keto-beta-hydroxylacyl reductoisomerase
E3D14_00450	ENOG4107QP8	phosphohexose isomerase
E3D14_00465	ENOG4105D64	Mechanosensitive ion channel
E3D14_00470	ENOG4105EC0	Required for nucleoid occlusion (NO) phenomenon, which prevents Z-ring formation and cell division over the nucleoid. Acts as a DNA-associated cell division inhibitor that binds simultaneously chromosomal DNA and FtsZ, and disrupts the assembly of FtsZ polymers. SlmA-DNA-binding sequences (SBS) are dispersed on non-Ter regions of the chromosome, preventing FtsZ polymerization at these regions (By similarity)
E3D14_00475	ENOG4108Z1K	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA (By similarity)
E3D14_00480	ENOG4105CJS	Phosphopantothenoylcysteine decarboxylase
E3D14_00485	ENOG4105W5Q	DNA repair protein (RadC
E3D14_00490	ENOG4105KDC	50s ribosomal protein l28
E3D14_00495	ENOG4105W0E	50S ribosomal protein L33
E3D14_00505	ENOG4105ERD	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity)
E3D14_00510	ENOG4108MJ5	VirK protein
E3D14_00515	ENOG4108ZEF	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity)
E3D14_00520	ENOG4105M5K	heptosyltransferase
E3D14_00525	ENOG4106WTF	Glycosyl transferase, family 2
E3D14_00530	ENOG4105XA0	heptosyltransferase ii
E3D14_00535	ENOG4105D8A	3-Deoxy-D-manno-octulosonic-acid transferase
E3D14_00550	ENOG4106ETB	IIa component
E3D14_00555	ENOG4105DIQ	Transcriptional regulator
E3D14_00580	ENOG4105X6C	Flagellar basal body-associated protein FliL
E3D14_00585	ENOG4105VEI	Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4- hydroxybenzoate (4HB) for the ubiquinone pathway (By similarity)
E3D14_00590	ENOG4105C4G	Synthesis of 3-octaprenyl-4-hydroxybenzoate (By similarity)
E3D14_00595	ENOG4105E55	glycerol-3-phosphate acyltransferase
E3D14_00600	ENOG4105DS7	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity)
E3D14_00620	ENOG4108UIQ	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity)
E3D14_00625	ENOG4105E0F	Histidine kinase
E3D14_00630	ENOG4105E3W	Two component transcriptional regulator (Winged helix family
E3D14_00640	ENOG4105D7W	serine acetyltransferase
E3D14_00650	ENOG41065UX	Non-essential, abundant cell division factor that is required for proper Z-ring formation. It is recruited early to the divisome by direct interaction with FtsZ, stimulating Z-ring assembly and thereby promoting cell division earlier in the cell cycle. Its recruitment to the Z-ring requires functional FtsA or ZipA (By similarity)
E3D14_00655	ENOG4108556	Isoprenoid biosynthesis protein with amidotransferase-like domain
E3D14_00665	ENOG4105C2M	dna polymerase I
E3D14_00670	ENOG4108Z0R	Transferase
E3D14_00715	ENOG4105DHU	Bile acid
E3D14_00720	ENOG4105E46	N-alpha,N-alpha,N-alpha-trimethyl-L-histidine metabolic process
E3D14_00730	ENOG4105C4W	S-formylglutathione hydrolase
E3D14_00740	ENOG4105CC0	LysR family Transcriptional regulator
E3D14_00750	ENOG4105UIB	(ABC) transporter
E3D14_00755	ENOG4108JQ9	ABC transporter
E3D14_00765	ENOG4105C4R	Atp-dependent dna helicase
E3D14_00800	ENOG4105K3G	Periplasmic Protein
E3D14_00820	ENOG4105EJC	lysr family transcriptional regulator
E3D14_00825	ENOG410829K	Lysine exporter protein (Lyse ygga)
E3D14_00830	ENOG4105CUC	YeeE YedE family protein
E3D14_00835	ENOG4105C52	Atpase, p-type (Transporting), had superfamily, subfamily ic
E3D14_00845	ENOG4105ECQ	AraC Family Transcriptional Regulator
E3D14_00850	ENOG4105FR1	rard protein
E3D14_00860	ENOG4105C26	Dehydrogenase
E3D14_00875	ENOG4105C26	Dehydrogenase
E3D14_00880	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
E3D14_00885	ENOG4105DCF	alanine dehydrogenase
E3D14_00890	ENOG4108TFM	Kinase, PfkB family
E3D14_00910	ENOG4105CGY	Dna recombination protein
E3D14_00915	ENOG4105D37	Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA (By similarity)
E3D14_00920	ENOG4105C1A	potassium transporter peripheral membrane
E3D14_00925	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
E3D14_00930	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
E3D14_00935	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
E3D14_00940	ENOG4108WZM	domain protein
E3D14_00945	ENOG4105C79	DNA protecting protein DprA
E3D14_00950	ENOG4108RPN	Protein smg homolog
E3D14_00955	ENOG4108WI1	Dna topoisomerase
E3D14_00965	ENOG4105EK0	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
E3D14_00970	ENOG4105DBS	Key enzyme in heme biosynthesis. Catalyzes the oxidative decarboxylation of propionic acid side chains of rings A and B of coproporphyrinogen III (By similarity)
E3D14_00975	ENOG4105E2X	shikimate dehydrogenase
E3D14_00980	ENOG4105SG3	Protein of unknown function (DUF1488)
E3D14_00985	ENOG4105WHM	Necessary for normal cell division and for the maintenance of normal septation (By similarity)
E3D14_00990	ENOG4106RE7	Cytochrome
E3D14_00995	ENOG4105ZR3	A GTPase-activating protein (GAP) that modifies Der EngA GTPase function. May play a role in ribosome biogenesis (By similarity)
E3D14_01000	ENOG4105XCT	Protein of unknown function (DUF2489)
E3D14_01005	ENOG4105D4P	Coproporphyrinogen iii oxidase
E3D14_01010	ENOG4105EKD	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism (By similarity)
E3D14_01015	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
E3D14_01020	ENOG4105CUX	Signal transduction histidine kinase
E3D14_01030	ENOG4105C5F	glutamine synthetase
E3D14_01040	ENOG4107S2Z	UPF0761 membrane protein
E3D14_01055	ENOG4105SUU	thioesterase domain
E3D14_01065	ENOG4105CB5	ATP-dependent DNA helicase recG
E3D14_01070	ENOG4105JIM	Phosphatidylserine synthase
E3D14_01075	ENOG4105C6Z	Gluconate
E3D14_01080	ENOG4108Z67	carbohydrate kinase, thermoresistant glucokinase family
E3D14_01085	ENOG4105C01	Dihydroxy-acid dehydratase
E3D14_01090	ENOG4108UHU	Aldolase
E3D14_01105	ENOG41063SB	peptidase
E3D14_01110	ENOG4105CJI	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
E3D14_01115	ENOG4107YZP	Rhodanese domain protein
E3D14_01120	ENOG4105IX2	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA (By similarity)
E3D14_01125	ENOG4105CSF	NADPH-dependent glycerol-3-phosphate dehydrogenase
E3D14_01130	ENOG4107RUK	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins (By similarity)
E3D14_01135	ENOG4105MJ2	Competence protein
E3D14_01140	ENOG4105D3C	The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters (By similarity)
E3D14_01160	ENOG4105BZM	domain protein
E3D14_01165	ENOG4108RRZ	Transcription elongation factor GreB
E3D14_01170	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
E3D14_01175	ENOG4105E0F	Histidine kinase
E3D14_01185	ENOG4108Z10	Involved in the binding of tRNA to the ribosomes (By similarity)
E3D14_01190	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
E3D14_01195	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
E3D14_01200	ENOG41080KG	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
E3D14_01205	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
E3D14_01210	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
E3D14_01215	ENOG4105KAP	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity)
E3D14_01220	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
E3D14_01225	ENOG4108R70	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity)
E3D14_01230	ENOG41083MP	50s ribosomal protein l29
E3D14_01235	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
E3D14_01240	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
E3D14_01245	ENOG4105KAR	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity)
E3D14_01250	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
E3D14_01255	ENOG4105VBI	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
E3D14_01260	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
E3D14_01265	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
E3D14_01270	ENOG4105K4C	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity)
E3D14_01275	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
E3D14_01280	ENOG4105VPB	50S ribosomal protein L30
E3D14_01285	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
E3D14_01290	ENOG4105CGG	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity)
E3D14_01295	ENOG41067V7	50S ribosomal protein L36
E3D14_01300	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
E3D14_01305	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
E3D14_01310	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
E3D14_01315	ENOG4105CTF	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
E3D14_01320	ENOG4108ZT0	50S ribosomal protein l17
E3D14_01365	ENOG4105F5W	AtP-binding protein
E3D14_01370	ENOG4105D70	Integrase catalytic subunit
E3D14_01380	ENOG4105CMT	Dihydroxyacetone kinase
E3D14_01385	ENOG4108UTZ	Dihydroxyacetone kinase
E3D14_01390	ENOG4105VDH	Dihydroxyacetone kinase
E3D14_01400	ENOG4108JU9	GAF modulated sigma54 specific transcriptional regulator Fis family
E3D14_01405	ENOG4105IPI	Membrane
E3D14_01435	ENOG4105CH6	catalase
E3D14_01460	ENOG4105BZU	Histidine kinase
E3D14_01470	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
E3D14_01515	ENOG4105C2I	pirin domain protein
E3D14_01520	ENOG4108VBZ	doxx family
E3D14_01525	ENOG4105DSY	exodeoxyribonuclease V, gamma
E3D14_01530	ENOG4107QKA	exodeoxyribonuclease V beta
E3D14_01535	ENOG4107QYX	exodeoxyribonuclease v alpha
E3D14_01545	ENOG4105KHA	Glyoxalase Bleomycin resistance protein (Dioxygenase
E3D14_01565	ENOG4108YZA	Nitrogen regulatory protein pii
E3D14_01570	ENOG4105BZU	Histidine kinase
E3D14_01580	ENOG4105C8Q	Methyl-accepting chemotaxis
E3D14_01600	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
E3D14_01605	ENOG4105E0F	Histidine kinase
E3D14_01610	ENOG4106TD9	Diguanylate cyclase
E3D14_01620	ENOG4105VEQ	Cold shock protein
E3D14_01630	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
E3D14_01635	ENOG41086KC	Transcriptional regulator
E3D14_01640	ENOG4108UUM	single-stranded DNA-binding protein
E3D14_01655	ENOG41076HS	cation diffusion facilitator family transporter
E3D14_01685	ENOG4105CKD	glutathione-regulated potassium-efflux system protein
E3D14_01690	ENOG4108K2R	Glutathione-regulated potassium-efflux system ancillary protein
E3D14_01705	ENOG4105CUG	Oligopeptidase b
E3D14_01730	ENOG4107FS9	Membrane
E3D14_01760	ENOG4105VVZ	metal-binding protein
E3D14_01765	ENOG41076UM	multiple antibiotic resistance (MarC)-related protein
E3D14_01775	ENOG4105WKS	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity)
E3D14_01785	ENOG4105CHQ	Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella (By similarity)
E3D14_01790	ENOG4107RZC	phospholipase d
E3D14_01800	ENOG4105EJ2	Transcriptional regulator
E3D14_01820	ENOG4106H78	methyltransferase
E3D14_01825	ENOG4105CCP	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
E3D14_01830	ENOG4105CAK	Cell division ATP-binding protein ftsE
E3D14_01835	ENOG4105CRP	Part of the ABC transporter FtsEX involved in
E3D14_01840	ENOG4105DEK	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
E3D14_01845	ENOG41077A9	carbonic anhydrase
E3D14_01850	ENOG4105CZE	histidine utilization repressor
E3D14_01855	ENOG4105CI2	imidazolone-5-propionate hydrolase
E3D14_01860	ENOG41088SP	formiminoglutamate hydrolase
E3D14_01865	ENOG4105CGP	Urocanate hydratase
E3D14_01870	ENOG4105C84	Histidine ammonia-lyase
E3D14_01875	ENOG4105EWV	Sodium calcium exchanger membrane region
E3D14_01880	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
E3D14_01885	ENOG41062P1	Diguanylate cyclase phosphodiesterase
E3D14_01915	ENOG4105GVR	general secretion pathway protein D
E3D14_01945	ENOG4105DFF	Rod shape-determining protein mreb
E3D14_01950	ENOG4105N3I	Involved in formation and maintenance of cell shape (By similarity)
E3D14_01955	ENOG4105VQ7	Rod shape-determining protein MreD
E3D14_01960	ENOG4108Z03	MAF-like protein
E3D14_01965	ENOG4105C03	ribonuclease
E3D14_01970	ENOG4105QD6	exported protein
E3D14_01985	ENOG4105D1U	peptidase U62 modulator of DNA gyrase
E3D14_02010	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
E3D14_02015	ENOG4105BZU	Histidine kinase
E3D14_02020	ENOG4105QD0	anti-sigma regulatory factor serine threonine protein kinase
E3D14_02025	ENOG4107MMM	Anti-sigma-factor antagonist
E3D14_02030	ENOG4107SDU	Methyl-accepting chemotaxis
E3D14_02035	ENOG4105F0S	class B acid phosphatase
E3D14_02045	ENOG4108HU6	Metal dependent phosphohydrolase
E3D14_02060	ENOG4105EEQ	Na H antiporter
E3D14_02065	ENOG4105C3R	Methionine synthase
E3D14_02070	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
E3D14_02080	ENOG4105ETX	regulatoR
E3D14_02100	ENOG4105CBF	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction (By similarity)
E3D14_02105	ENOG4108UV6	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity)
E3D14_02110	ENOG4105D06	uba thif-type nad fad binding protein
E3D14_02120	ENOG4105CA8	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity)
E3D14_02125	ENOG4105D41	biosynthesis protein thiH
E3D14_02165	ENOG4105EQK	-acetyltransferase
E3D14_02170	ENOG4108WEF	Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1B (PBP1b) (By similarity)
E3D14_02185	ENOG4105C44	Serine transporter
E3D14_02190	ENOG4108TPP	exopolysaccharide synthesis
E3D14_02200	ENOG4105N0V	mono-oxygenase ydhR
E3D14_02240	ENOG4105CBT	Fructose-1,6-bisphosphatase
E3D14_02255	ENOG4105ECF	c-methyltransferase
E3D14_02260	ENOG41076E6	Uroporphyrinogen-III Synthase
E3D14_02265	ENOG4105D6W	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity)
E3D14_02270	ENOG4107T0K	Adenylate cyclase
E3D14_02290	ENOG4105XQ6	frataxin-like protein
E3D14_02300	ENOG4105CU5	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity)
E3D14_02305	ENOG4105E4Z	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan (By similarity)
E3D14_02315	ENOG4108IYS	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
E3D14_02320	ENOG4105DFC	had-superfamily hydrolase, subfamily ia, variant
E3D14_02330	ENOG4105D64	Mechanosensitive ion channel
E3D14_02340	ENOG4108Z86	Glutamine amidotransferase
E3D14_02345	ENOG410667J	hydrolase
E3D14_02360	ENOG4105CJ1	ABC, transporter
E3D14_02370	ENOG4108I62	cina-like protein
E3D14_02375	ENOG4105E4Y	Endoribonuclease that initiates mRNA decay (By similarity)
E3D14_02380	ENOG4105CVG	Homoserine O-transsuccinylase
E3D14_02390	ENOG4108YXU	transcriptional regulator AsnC family
E3D14_02395	ENOG4105E0M	Sulfatase
E3D14_02415	ENOG4105KT7	mgtC SapB transporter
E3D14_02435	ENOG4105EMU	Dehydrogenase
E3D14_02440	ENOG4105DZW	Dipeptidase
E3D14_02455	ENOG4108I6A	alcohol dehydrogenase
E3D14_02465	ENOG4108IQK	o-acetylhomoserine
E3D14_02475	ENOG4105KNR	Activates the small RNA gene sgrS under glucose- phosphate stress conditions as well as yfdZ. Represses its own transcription under both stress and non-stress conditions. Might act as a sensor of the intracellular accumulation of phosphoglucose by binding these molecules in its C-terminal solute-binding domain (By similarity)
E3D14_02480	ENOG4105C1X	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity (By similarity)
E3D14_02500	ENOG4107IFA	Lipase (EC 3.1.1.3)
E3D14_02510	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
E3D14_02515	ENOG4108UB4	uncharacterized protein ygjQ
E3D14_02520	ENOG4107MM9	BNR Asp-box repeat-containing protein
E3D14_02530	ENOG4105HMV	Fimbrial protein
E3D14_02540	ENOG4106PG1	outer membrane usher protein
E3D14_02545	ENOG4108FZ9	Chaperone
E3D14_02550	ENOG4105NEV	Fimbrial
E3D14_02565	ENOG4105CEY	Amp-dependent synthetase and ligase
E3D14_02570	ENOG4105DNI	Converts SHCHC to OSB (By similarity)
E3D14_02575	ENOG4108IPT	Naphthoate synthase
E3D14_02580	ENOG4107J5P	Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC). Is also able to catalyze the hydrolysis of the thioester bond in palmitoyl-CoA in vitro (By similarity)
E3D14_02585	ENOG4105C4A	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC) (By similarity)
E3D14_02590	ENOG4105E4F	Isochorismate synthase
E3D14_02595	ENOG4105EIS	1,4-dihydroxy-2-naphthoate octaprenyltransferase
E3D14_02620	ENOG4105C1J	atp-dependent rna helicase
E3D14_02625	ENOG4105D9N	nucleoside
E3D14_02630	ENOG4107K5X	Membrane-bound metal-dependent hydrolase
E3D14_02645	ENOG4108UPT	UPF0178 protein
E3D14_02665	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
E3D14_02670	ENOG4105C3N	Participates in control of cell volume in low-osmolarity conditions (By similarity)
E3D14_02675	ENOG4105E61	Mannitol repressor protein
E3D14_02680	ENOG4107SQ3	mannitol-1-phosphate 5-dehydrogenase
E3D14_02685	ENOG4105CTS	PTS system mannitol-specific
E3D14_02700	ENOG4108IEC	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction (By similarity)
E3D14_02705	ENOG4105CXD	Specific inhibitor of chromosomal initiation of replication in vitro. Binds the three 13-mers in the origin (oriC) to block initiation of replication (By similarity)
E3D14_02710	ENOG4105NNS	Autoinducer synthesis protein
E3D14_02715	ENOG4105VJY	transcriptional regulator
E3D14_02720	ENOG4108ZUB	Lysine exporter protein (Lyse ygga)
E3D14_02725	ENOG4107RNS	bifunctional 2',3'-cyclic nucleotide 2'-phosphodiesterase 3'-nucleotidase periplasmic
E3D14_02730	ENOG4108XTF	Outer Membrane Lipoprotein
E3D14_02735	ENOG4108R6G	acetyltransferase
E3D14_02740	ENOG4105VXR	cytoplasmic protein
E3D14_02755	ENOG4105DJ1	Phosphoenolpyruvate Carboxylase
E3D14_02760	ENOG4105F4C	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress (By similarity)
E3D14_02765	ENOG4105VEJ	Heat shock protein
E3D14_02770	ENOG4108XKW	General secretion pathway protein C
E3D14_02775	ENOG4105GVR	general secretion pathway protein D
E3D14_02780	ENOG4107QHF	type ii secretion system protein e
E3D14_02785	ENOG4105D7Q	type ii secretion system
E3D14_02790	ENOG4108VAU	general secretion pathway protein G
E3D14_02830	ENOG4108UDW	Transcriptional regulator, luxr family
E3D14_02835	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
E3D14_02840	ENOG4107Y3D	HAD-superfamily hydrolase subfamily IA variant 3
E3D14_02845	ENOG4107RK2	ADP-ribose diphosphatase NudE
E3D14_02850	ENOG4108RNI	3'(2')5'-bisphosphate nucleotidase
E3D14_02855	ENOG4105C44	Serine transporter
E3D14_02860	ENOG4108Z7R	Chaperone CsaA
E3D14_02870	ENOG4105GGQ	This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis (By similarity)
E3D14_02875	ENOG4105C28	cystathionine
E3D14_02880	ENOG4105CFH	Aspartokinase
E3D14_02895	ENOG41067MG	lrgb family
E3D14_02935	ENOG4108Z66	YbaK ebsC protein
E3D14_02940	ENOG4107TH8	cina domain protein
E3D14_02945	ENOG4105C68	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity)
E3D14_02955	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
E3D14_02960	ENOG4105CFH	Aspartokinase
E3D14_02965	ENOG4105VM8	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding (By similarity)
E3D14_02990	ENOG41061WM	D-Alanyl-D-Alanine
E3D14_02995	ENOG4106W5V	Membrane
E3D14_03010	ENOG4105MYG	DNA polymerase iii, chi subunit
E3D14_03015	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
E3D14_03020	ENOG4108M8S	permease YjgP YjgQ family protein
E3D14_03025	ENOG4108K5H	permease YjgP YjgQ family protein
E3D14_03165	ENOG4105ED4	portal protein
E3D14_03250	ENOG4105M7P	phage repressor
E3D14_03255	ENOG4108IYS	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
E3D14_03260	ENOG4105DFP	Integrase
E3D14_03280	ENOG4105XB7	anti-repressor protein
E3D14_03325	ENOG4107R3N	Filamentation induced by cAMP protein fic
E3D14_03330	ENOG4105BZU	Histidine kinase
E3D14_03335	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
E3D14_03340	ENOG4105VDT	-acetyltransferase
E3D14_03355	ENOG4105EYA	deoxyribonuclease
E3D14_03360	ENOG4105D9N	nucleoside
E3D14_03370	ENOG4105FCI	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate (By similarity)
E3D14_03375	ENOG4105CMW	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis (By similarity)
E3D14_03380	ENOG4105CZG	Phosphotransfer between the C1 and C5 carbon atoms of pentose (By similarity)
E3D14_03385	ENOG4105D3A	purine nucleoside phosphorylase DeoD-type
E3D14_03395	ENOG4105EAC	phosphoserine phosphatase
E3D14_03410	ENOG4105DNJ	May play a role in the repair of endogenous alkylation damage (By similarity)
E3D14_03420	ENOG4108ZVW	Anti-RNA polymerase sigma 70 factor
E3D14_03425	ENOG4105K70	DNA-binding protein
E3D14_03440	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
E3D14_03445	ENOG4105MYN	Zinc uptake regulation protein
E3D14_03460	ENOG4105CWM	branched-chain amino acid transport system II carrier protein
E3D14_03465	ENOG4107S47	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC) (By similarity)
E3D14_03470	ENOG4105C1J	atp-dependent rna helicase
E3D14_03475	ENOG4105D1Q	UPF0246 protein
E3D14_03480	ENOG4105CZX	twitching motility protein
E3D14_03485	ENOG4105CZX	twitching motility protein
E3D14_03490	ENOG4105DFA	alanine racemase domain protein
E3D14_03495	ENOG4105II7	pyrroline-5-carboxylate reductase
E3D14_03500	ENOG4108VIA	integral membrane protein
E3D14_03505	ENOG4105VZ9	UPF0235 protein
E3D14_03520	ENOG4107QSI	ABC, transporter
E3D14_03530	ENOG4105EQK	-acetyltransferase
E3D14_03535	ENOG4106WH9	Protein of unknown function (DUF2753)
E3D14_03540	ENOG41060WC	Enoyl-CoA hydratase
E3D14_03555	ENOG4108RZ4	Short-chain dehydrogenase reductase Sdr
E3D14_03565	ENOG4105DWY	Agmatine deiminase
E3D14_03570	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
E3D14_03590	ENOG4107YH7	Beta-lactamase (EC 3.5.2.6)
E3D14_03600	ENOG4105C1J	atp-dependent rna helicase
E3D14_03620	ENOG4107V4F	S-adenosyl-l-methionine hydroxide adenosyltransferase
E3D14_03650	ENOG4107QWG	2-Nitropropane dioxygenase
E3D14_03680	ENOG4105E09	nadh pyrophosphatase
E3D14_03685	ENOG4105E0F	Histidine kinase
E3D14_03690	ENOG4105E3W	Two component transcriptional regulator (Winged helix family
E3D14_03695	ENOG4105DJY	efflux transporter, rnd family, mfp subunit
E3D14_03700	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
E3D14_03710	ENOG4108GAE	asmA family
E3D14_03735	ENOG4105CE6	Adenylation and deadenylation of glutamate--ammonia ligase (By similarity)
E3D14_03740	ENOG410787A	Pts system, glucitol sorbitol-specific
E3D14_03745	ENOG4105DZY	Pts system, glucitol sorbitol-specific
E3D14_03750	ENOG4105VI0	Pts system, glucitol sorbitol-specific
E3D14_03755	ENOG4107QMF	Sorbitol-6-phosphate dehydrogenase
E3D14_03765	ENOG410804X	Transcriptional regulator
E3D14_03770	ENOG4105CE6	Adenylation and deadenylation of glutamate--ammonia ligase (By similarity)
E3D14_03785	ENOG4105EJF	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity)
E3D14_03790	ENOG4105CJH	Alcohol dehydrogenase zinc-binding domain protein
E3D14_03795	ENOG4108ZHJ	Organic hydroperoxide resistance protein
E3D14_03800	ENOG4105K56	Transcriptional regulator
E3D14_03815	ENOG4105EW9	transcriptional regulator AsnC family
E3D14_03835	ENOG4108K4B	hydrolase
E3D14_03850	ENOG4105C8J	)-transporter
E3D14_03860	ENOG4105C8J	)-transporter
E3D14_03910	ENOG4105XEP	YhcH YjgK YiaL family protein
E3D14_03920	ENOG4105CUY	Mechanosensitive ion channel
E3D14_03925	ENOG4107N1Q	ErfK YbiS YcfS YnhG family protein
E3D14_03930	ENOG4105CK7	Sodium proline symporter
E3D14_03940	ENOG4108Z6Z	Transcriptional regulator
E3D14_04010	ENOG4105D6S	protein involved in catabolism of external DNA
E3D14_04020	ENOG4105C5H	ABC transporter
E3D14_04025	ENOG4105C2X	Arabinose 5-phosphate isomerase
E3D14_04030	ENOG4105G5H	Membrane
E3D14_04035	ENOG4107QX8	SPFH domain, Band 7 family protein
E3D14_04040	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
E3D14_04045	ENOG4105C11	sulfate adenylyltransferase), subunit 2
E3D14_04050	ENOG4105C3T	may be the GTPase, regulating ATP sulfurylase activity (By similarity)
E3D14_04060	ENOG4108I67	Catalyzes the synthesis of activated sulfate (By similarity)
E3D14_04075	ENOG4107RHT	methyl-accepting chemotaxis sensory transducer with Pas Pac sensor
E3D14_04110	ENOG4108UUE	Transcriptional regulator
E3D14_04130	ENOG4105DKQ	ROK family
E3D14_04135	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
E3D14_04140	ENOG4105BZA	Phosphoglycerate kinase
E3D14_04145	ENOG4105D2N	Aldolase
E3D14_04150	ENOG4105CJP	fad dependent oxidoreductase
E3D14_04200	ENOG4108IYU	L-aspartate oxidase
E3D14_04205	ENOG4105EMN	RNA polymerase sigma factor
E3D14_04210	ENOG41069PW	sigma-e factor negative regulatory protein
E3D14_04225	ENOG4105C4S	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity)
E3D14_04230	ENOG4105C3F	Signal peptidase i
E3D14_04245	ENOG41071DT	Involved in DNA repair and RecF pathway recombination (By similarity)
E3D14_04250	ENOG4105CSZ	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate (By similarity)
E3D14_04255	ENOG4108VBV	N-Acetylmuramoyl-L-alanine amidase
E3D14_04260	ENOG4108W15	Protein of unknown function (DUF1456)
E3D14_04265	ENOG4105BZU	Histidine kinase
E3D14_04270	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
E3D14_04275	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
E3D14_04280	ENOG4105DXN	mazG family
E3D14_04285	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
E3D14_04290	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
E3D14_04295	ENOG4105XX3	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity)
E3D14_04300	ENOG4105CE5	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) (By similarity)
E3D14_04305	ENOG4108UH8	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (By similarity)
E3D14_04310	ENOG4106NZV	Responsible for synthesis of pseudouridine from uracil- 13 in transfer RNAs (By similarity)
E3D14_04315	ENOG4105CV2	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates (By similarity)
E3D14_04320	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
E3D14_04325	ENOG4108UM1	dedA family
E3D14_04330	ENOG4108K5P	(LipO)protein
E3D14_04335	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
E3D14_04340	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
E3D14_04345	ENOG4105VCC	30S ribosomal protein S21
E3D14_04350	ENOG4105KTH	gatB Yqey
E3D14_04355	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
E3D14_04360	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
E3D14_04405	ENOG4105C12	Phosphoribosylglycinamide synthetase
E3D14_04410	ENOG4105DC1	bifunctional purine biosynthesis protein purh
E3D14_04420	ENOG4105NAE	bifunctional deaminase-reductase domain protein
E3D14_04425	ENOG4105VCN	Rescues the ribosomes stalled at the 3' end of non-stop mRNAs. May induce hydrolysis of the ribosome-bound peptidyl-tRNA. This activity is crucial when the stalled ribosome can not be rescued by the SsrA(tmRNA)-SmpB quality control system
E3D14_04430	ENOG4105CSA	Coproporphyrinogen iii oxidase
E3D14_04435	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
E3D14_04460	ENOG4105D9U	N-acetyltransferase
E3D14_04480	ENOG4105EV4	Multidrug resistance protein mdtH
E3D14_04490	ENOG4105DS2	Anaerobic c4-dicarboxylate transporter
E3D14_04495	ENOG4108IJ0	Aspartate ammonia-lyase
E3D14_04500	ENOG4108YH1	overproduction of this protein in Escherichia coli inhibits the F plasmid-mediated exclusion of bacteriophage T7
E3D14_04510	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
E3D14_04515	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
E3D14_04525	ENOG4105BZU	Histidine kinase
E3D14_04535	ENOG4105D3G	Pseudouridine synthase
E3D14_04540	ENOG4105BZK	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair (By similarity)
E3D14_04570	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
E3D14_04580	ENOG4108IAB	Phoh family
E3D14_04585	ENOG4107T0D	ABC, transporter
E3D14_04590	ENOG4106SMU	thiamine transporter membrane protein
E3D14_04595	ENOG4105DP9	ABC transporter
E3D14_04610	ENOG4105MQS	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
E3D14_04615	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
E3D14_04625	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
E3D14_04635	ENOG4105YVM	Phosphoesterase, PA-phosphatase related
E3D14_04650	ENOG4105C7K	acetolactate synthase
E3D14_04655	ENOG4108ZP8	Acetolactate synthase small subunit
E3D14_04660	ENOG4105C6K	Malic enzyme
E3D14_04665	ENOG4105C6H	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity)
E3D14_04670	ENOG4105PQ6	UPF0208 membrane protein
E3D14_04675	ENOG4105XWI	UPF0304 protein
E3D14_04680	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
E3D14_04685	ENOG4105RH4	Glycine cleavage system transcriptional repressor
E3D14_04690	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
E3D14_04695	ENOG4107EG0	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
E3D14_04700	ENOG4107QWK	SAICAR synthetase
E3D14_04710	ENOG4105EXG	Transcriptional regulator
E3D14_04735	ENOG4105BZU	Histidine kinase
E3D14_04760	ENOG4108N3W	hemolysin secretion protein
E3D14_04765	ENOG4105MDZ	Transcriptional activator rfaH
E3D14_04770	ENOG4105D01	(LipO)protein
E3D14_04775	ENOG4108UMI	ABC transporter, permease
E3D14_04805	ENOG4105K8N	protein family UPF0079, ATPase
E3D14_04810	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
E3D14_04815	ENOG4105DC6	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity)
E3D14_04820	ENOG4105DKX	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity)
E3D14_04825	ENOG4105KW8	RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity)
E3D14_04830	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
E3D14_04835	ENOG4107QJR	hflk protein
E3D14_04840	ENOG4105EPW	hflc protein
E3D14_04850	ENOG4105EAH	synthase
E3D14_04855	ENOG4105KK9	This protein binds to 23S rRNA in the presence of protein L20 (By similarity)
E3D14_04860	ENOG4105K46	50S ribosomal protein l27
E3D14_04865	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
E3D14_04870	ENOG4105DWD	nucleoside recognition domain protein
E3D14_04885	ENOG4108ESY	Metal dependent phosphohydrolase
E3D14_04895	ENOG4105DEN	Luciferase family
E3D14_04910	ENOG4105DDT	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP (By similarity)
E3D14_04915	ENOG4105NWN	ApaG protein
E3D14_04920	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
E3D14_04925	ENOG4105CEZ	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) (By similarity)
E3D14_04935	ENOG4105E7H	involved in the assembly of LPS in the outer leaflet of the outer membrane. Determines N-hexane tolerance and is involved in outer membrane permeability. Essential for envelope biogenesis (By similarity)
E3D14_04940	ENOG4105EHM	Aminoglycoside phosphotransferase
E3D14_04945	ENOG4108S0S	Nucleotidyl transferase
E3D14_04950	ENOG41066UG	Regulatory DnaK co-chaperone. Direct interaction between DnaK and DjlA is needed for the induction of the wcaABCDE operon, involved in the synthesis of a colanic acid polysaccharide capsule, possibly through activation of the RcsB RcsC phosphotransfer signaling pathway. The colanic acid capsule may help the bacterium survive conditions outside the host (By similarity)
E3D14_04965	ENOG4105C5H	ABC transporter
E3D14_04990	ENOG4105EHG	Permease protein
E3D14_05000	ENOG41090JE	Utilization Protein
E3D14_05005	ENOG4105PYN	Pyridoxamine 5-phosphate oxidase-related
E3D14_05025	ENOG4105D05	Receptor
E3D14_05030	ENOG4105D8G	Major Facilitator superfamily
E3D14_05040	ENOG4105VMP	Transcriptional regulator
E3D14_05060	ENOG4108MA4	Peptidase M66
E3D14_05065	ENOG4108M1A	Chitin-binding protein
E3D14_05075	ENOG4107RYR	Transcriptional regulator, Crp Fnr family
E3D14_05080	ENOG4108UKZ	OsmC family
E3D14_05095	ENOG4105CJE	phosphoribulokinase (EC 2.7.1.19)
E3D14_05100	ENOG4105PE8	Translocates 4-amino-4-deoxy-L-arabinose- phosphoundecaprenol (alpha-L-Ara4N-phosphoundecaprenol) from the cytoplasmic to the periplasmic side of the inner membrane (By similarity)
E3D14_05105	ENOG41060GT	Translocates 4-amino-4-deoxy-L-arabinose- phosphoundecaprenol (alpha-L-Ara4N-phosphoundecaprenol) from the cytoplasmic to the periplasmic side of the inner membrane (By similarity)
E3D14_05110	ENOG4105SA9	Catalyzes the transfer of the L-Ara4N moiety of the glycolipid undecaprenyl phosphate-alpha-L-Ara4N to lipid A. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides (By similarity)
E3D14_05115	ENOG4105F73	Catalyzes the deformylation of 4-deoxy-4-formamido-L- arabinose-phosphoundecaprenol to 4-amino-4-deoxy-L-arabinose- phosphoundecaprenol. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides (By similarity)
E3D14_05125	ENOG4105CKK	Glycosyl transferase, family 2
E3D14_05130	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
E3D14_05135	ENOG4105C6Y	Udp-glucose 6-dehydrogenase
E3D14_05140	ENOG4105YP7	UPF0270 protein
E3D14_05150	ENOG4105DNZ	Alpha Beta Hydrolase
E3D14_05155	ENOG4107R88	Chemotaxis protein (CheV)
E3D14_05165	ENOG4105VKU	nucleicacid-binding protein
E3D14_05170	ENOG4108YZY	peptidylprolyl cis-trans isomerase
E3D14_05175	ENOG4105VRX	Protein slyX homolog
E3D14_05185	ENOG4108V1T	peptidylprolyl cis-trans isomerase
E3D14_05190	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
E3D14_05210	ENOG4105CGH	5'-nucleotidase
E3D14_05230	ENOG4105CDU	Replicative dna helicase
E3D14_05235	ENOG4105CDU	Replicative dna helicase
E3D14_05240	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
E3D14_05245	ENOG4105K5D	4fe-4S ferredoxin iroN-sulfur binding
E3D14_05250	ENOG4105CFP	Peptidase U32
E3D14_05255	ENOG4108NJZ	Sensory box GGDEF EAL domain protein
E3D14_05285	ENOG4105BZU	Histidine kinase
E3D14_05310	ENOG4105C9B	Cysteine desulfurase
E3D14_05315	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
E3D14_05320	ENOG4108Z4W	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis (By similarity)
E3D14_05325	ENOG4105BZU	Histidine kinase
E3D14_05330	ENOG4105C8Q	Methyl-accepting chemotaxis
E3D14_05335	ENOG4108V3W	Chemotaxis protein, CheW
E3D14_05345	ENOG4105CBS	Chea signal transduction histidine kinase
E3D14_05355	ENOG4108VYJ	response regulator receiver protein
E3D14_05365	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
E3D14_05375	ENOG4105N14	lysine exporter protein LysE YggA
E3D14_05390	ENOG4105XDF	Protein of unknown function (DUF1272)
E3D14_05400	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
E3D14_05415	ENOG4105CTD	carboxy-peptidase
E3D14_05440	ENOG4105E1F	short-chain dehydrogenase reductase
E3D14_05450	ENOG4108W2P	Methyl-accepting chemotaxis
E3D14_05485	ENOG4105CQC	Prephenate dehydratase
E3D14_05515	ENOG4107SEY	Conserved Protein
E3D14_05520	ENOG4108XDN	Transcriptional regulator
E3D14_05525	ENOG4105CVP	deoxyribo-dipyrimidine photolyase
E3D14_05535	ENOG4107FW0	short-chain dehydrogenase reductase
E3D14_05550	ENOG4105CV9	cyclopropane-fatty-acyl-phospholipid synthase
E3D14_05575	ENOG4108RMU	ferritin dps family protein
E3D14_05580	ENOG4105EJ7	Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O (By similarity)
E3D14_05590	ENOG4105CMR	udp-glucose 4-epimerase
E3D14_05595	ENOG4105DRC	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity)
E3D14_05610	ENOG4105E2V	Glycosyltransferase 36
E3D14_05630	ENOG4107S0N	DJ-1 family
E3D14_05635	ENOG4108JZF	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity)
E3D14_05640	ENOG4108VPT	UPF0234 protein
E3D14_05645	ENOG4105DRB	nucleoside-specific channel-forming protein
E3D14_05650	ENOG4105EYM	Major Facilitator superfamily
E3D14_05660	ENOG4108R5K	PPIases accelerate the folding of proteins (By similarity)
E3D14_05670	ENOG4105D8J	Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle (By similarity)
E3D14_05675	ENOG4105M85	Bola protein
E3D14_05685	ENOG4105DWQ	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
E3D14_05690	ENOG4108J5C	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
E3D14_05695	ENOG4106I92	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
E3D14_05700	ENOG4105F5D	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
E3D14_05705	ENOG4108IUB	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
E3D14_05710	ENOG4105D26	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. The first step is catalyzed by NqrF, which accepts electrons from NADH and reduces ubiquinone-1 to ubisemiquinone by a one-electron transfer pathway (By similarity)
E3D14_05715	ENOG4105CJ2	(LipO)protein
E3D14_05730	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
E3D14_05735	ENOG4105C8Q	Methyl-accepting chemotaxis
E3D14_05740	ENOG4105ETT	transcriptional Regulator, LysR family
E3D14_05750	ENOG4105M08	Membrane
E3D14_05755	ENOG4105EZ6	Catalyzes the 2'-O-methylation at nucleotide C2498 in 23S rRNA (By similarity)
E3D14_05765	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
E3D14_05770	ENOG4105CIQ	May have a role in processing of nucleic acids. It is probably not an exonuclease
E3D14_05775	ENOG4105EWT	decarboxylase family
E3D14_05780	ENOG4105BZU	Histidine kinase
E3D14_05790	ENOG4107R1K	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) (By similarity)
E3D14_05795	ENOG4108T6E	Interacts with the SecY protein in vivo. May bind preferentially to an uncomplexed state of SecY, thus functioning either as a chelating agent for excess SecY in the cell or as a regulatory factor that negatively controls the translocase function (By similarity)
E3D14_05800	ENOG4105EXF	Zn-ribbon-containing, possibly nucleic-acid-binding protein
E3D14_05825	ENOG4105WP7	tRNA pseudouridine synthase C
E3D14_05830	ENOG4105DR9	pseudouridine synthase
E3D14_05835	ENOG4105QDK	Flavodoxin
E3D14_05840	ENOG4108KDD	Involved in the transport of maltose and maltodextrins (By similarity)
E3D14_05860	ENOG4105CI1	PTS System
E3D14_05865	ENOG4108T8E	UPF0325 protein
E3D14_05870	ENOG4105DMJ	Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate (By similarity)
E3D14_05875	ENOG4105E1P	Modifies, by uridylylation or deuridylylation the PII (GlnB) regulatory protein (By similarity)
E3D14_05880	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
E3D14_05885	ENOG4105CE9	30S ribosomal protein S2
E3D14_05890	ENOG4105CU7	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity)
E3D14_05895	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
E3D14_05900	ENOG4108VCV	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity)
E3D14_05905	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
E3D14_05910	ENOG4105KNE	Phosphatidate cytidylyltransferase
E3D14_05915	ENOG4105CEA	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity)
E3D14_05920	ENOG4105DZP	Membrane-associated zinc metalloprotease
E3D14_05930	ENOG4108RFI	Molecular chaperone that interacts specifically with outer membrane proteins, thus maintaining the solubility of early folding intermediates during passage through the periplasm (By similarity)
E3D14_05935	ENOG4105D7M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
E3D14_05940	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
E3D14_05945	ENOG4105DAF	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
E3D14_05950	ENOG4105D0V	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
E3D14_05955	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
E3D14_05960	ENOG4105C0B	DNA polymerase III (alpha subunit)
E3D14_05965	ENOG4107QM9	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA (By similarity)
E3D14_05970	ENOG4108M3R	transcriptional activator CadC
E3D14_05975	ENOG4105D5Q	Arginine ornithine antiporter
E3D14_05980	ENOG4105CXN	decarboxylase
E3D14_05985	ENOG4107XGF	functions in a salvage pathway. Uses pyridoxamine (By similarity)
E3D14_05995	ENOG4105EQ2	LysR family Transcriptional regulator
E3D14_06000	ENOG4105C44	Serine transporter
E3D14_06005	ENOG4105DVH	amino acid
E3D14_06010	ENOG4105KNA	-acetyltransferase
E3D14_06015	ENOG4105C5H	ABC transporter
E3D14_06025	ENOG4105C9K	Endothelin-converting enzyme 1
E3D14_06030	ENOG4105D3U	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
E3D14_06035	ENOG4105BZU	Histidine kinase
E3D14_06090	ENOG4108V1U	phospholipid-binding protein
E3D14_06095	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
E3D14_06110	ENOG4105C87	Aminotransferase class I and II
E3D14_06120	ENOG4105C5Q	Transcriptional regulator
E3D14_06125	ENOG4105UBK	short-chain dehydrogenase reductase
E3D14_06130	ENOG4105ERU	peptidase
E3D14_06135	ENOG4105EY2	Catalyzes the hydrolysis of N(2)-succinylarginine into N(2)-succinylornithine, ammonia and CO(2) (By similarity)
E3D14_06140	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
E3D14_06150	ENOG4107RHT	methyl-accepting chemotaxis sensory transducer with Pas Pac sensor
E3D14_06155	ENOG4105E2D	ec 3.2.1.52
E3D14_06160	ENOG4105RD7	BadF BadG BcrA BcrD
E3D14_06170	ENOG4108JQ7	(ABC) transporter
E3D14_06180	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
E3D14_06195	ENOG4105BZU	Histidine kinase
E3D14_06215	ENOG4105XIQ	Protein of unknown function (DUF2517)
E3D14_06225	ENOG4107SDU	Methyl-accepting chemotaxis
E3D14_06230	ENOG4108ESY	Metal dependent phosphohydrolase
E3D14_06235	ENOG4105DR8	Membrane
E3D14_06240	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
E3D14_06245	ENOG4105C6R	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor (By similarity)
E3D14_06250	ENOG4108IUZ	ABC transporter
E3D14_06255	ENOG4107A5B	Binding-protein-dependent transport systems, inner membrane component
E3D14_06270	ENOG4105BZU	Histidine kinase
E3D14_06280	ENOG4107H9G	Necessary for formate dehydrogenase activity (By similarity)
E3D14_06285	ENOG4108J1Q	
E3D14_06320	ENOG4105EGS	Mechanosensitive ion channel
E3D14_06325	ENOG4105CA9	Pyruvate kinase
E3D14_06340	ENOG4105CKD	glutathione-regulated potassium-efflux system protein
E3D14_06345	ENOG4105CKD	glutathione-regulated potassium-efflux system protein
E3D14_06350	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
E3D14_06355	ENOG4105DH7	May be involved in recombination (By similarity)
E3D14_06365	ENOG4107RH8	nuclease SbcCD subunit D
E3D14_06370	ENOG4105EYH	Exonuclease
E3D14_06380	ENOG4105CPW	cytochrome b561
E3D14_06390	ENOG4105BZU	Histidine kinase
E3D14_06395	ENOG4105C5Y	PTS System
E3D14_06405	ENOG4105KZ7	phosphocarrier protein hpr
E3D14_06410	ENOG4105C6T	cysteine synthase
E3D14_06430	ENOG4108R96	Methyltransferase, YaeB family
E3D14_06450	ENOG4108JJ8	(ABC) transporter
E3D14_06455	ENOG4108JJ9	ABC, transporter
E3D14_06470	ENOG41065U4	response regulator
E3D14_06480	ENOG4108YYX	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. Modulates RNA-binding and helicase activities of the degradosome (By similarity)
E3D14_06495	ENOG4105VS7	Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue. This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon. When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation (By similarity)
E3D14_06500	ENOG4106FVC	RNA methyltransferase
E3D14_06515	ENOG4105D5I	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate (By similarity)
E3D14_06520	ENOG4105D98	threonine synthase
E3D14_06550	ENOG4108UK5	Transposase
E3D14_06570	ENOG4108QW8	Purine nucleoside phosphorylase deoD-type
E3D14_06585	ENOG4105C8E	extradiol ring-cleavage dioxygenase class IIi protein subunit b
E3D14_06590	ENOG4108V1T	peptidylprolyl cis-trans isomerase
E3D14_06600	ENOG4105CUB	amino acid
E3D14_06605	ENOG4105CUB	amino acid
E3D14_06610	ENOG4108JPW	Aminotransferase
E3D14_06615	ENOG4105C26	Dehydrogenase
E3D14_06620	ENOG4107VRI	Transcriptional regulator
E3D14_06625	ENOG4105CJP	fad dependent oxidoreductase
E3D14_06635	ENOG4105EZV	Transcriptional regulator
E3D14_06665	ENOG4105D5G	Transposase
E3D14_06680	ENOG4105Q26	Siderophore-interacting protein
E3D14_06685	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
E3D14_06690	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
E3D14_06695	ENOG4105DJY	efflux transporter, rnd family, mfp subunit
E3D14_06705	ENOG4105E2M	Manganese-dependent inorganic pyrophosphatase
E3D14_06710	ENOG4105C4F	May be involved in recombinational repair of damaged DNA (By similarity)
E3D14_06715	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
E3D14_06720	ENOG4105K90	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
E3D14_06725	ENOG4105CFG	Acts as a chaperone (By similarity)
E3D14_06730	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
E3D14_06740	ENOG4105D7K	pfkb domain protein
E3D14_06755	ENOG4105WBN	Transcriptional regulator (LacI family
E3D14_06780	ENOG41080HT	Transcriptional regulator, arsr family
E3D14_06805	ENOG4105BZU	Histidine kinase
E3D14_06810	ENOG4107RMF	Catalyzes both the ATP-dependent activation of exogenously supplied lipoate to lipoyl-AMP and the transfer of the activated lipoyl onto the lipoyl domains of lipoate-dependent enzymes (By similarity)
E3D14_06820	ENOG4108IJF	Heavy metal efflux pump, CzcA
E3D14_06825	ENOG4105EP1	Efflux transporter rnd family, mfp subunit
E3D14_06850	ENOG4105CGK	Exodeoxyribonuclease III
E3D14_06905	ENOG4105E2S	oxidase) subunit II
E3D14_06910	ENOG4105BZ9	Cytochrome C oxidase, subunit I
E3D14_06915	ENOG4105CCU	oxidase (Subunit III)
E3D14_06920	ENOG41090KH	cytochrome o ubiquinol oxidase (subunit iv)
E3D14_06925	ENOG4105F1R	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group (By similarity)
E3D14_06930	ENOG4107RDB	Major Facilitator
E3D14_06950	ENOG4107P2S	Transcriptional regulator
E3D14_06955	ENOG4105CI1	PTS System
E3D14_06960	ENOG4105C87	Aminotransferase class I and II
E3D14_06985	ENOG4105EIP	mannose-6-phosphate isomerase
E3D14_06990	ENOG4106R3P	AraC family transcriptional regulator
E3D14_06995	ENOG4108HMX	isocitrate dehydrogenase (NADP)
E3D14_07005	ENOG4105BZC	d-serine deaminase
E3D14_07015	ENOG4105W8I	Transcriptional regulator
E3D14_07100	ENOG4108UH4	Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity)
E3D14_07105	ENOG4108Z1B	Cyclase dehydrase
E3D14_07110	ENOG4105VDB	UPF0125 protein
E3D14_07115	ENOG4105K4T	epimerase
E3D14_07120	ENOG4105YRI	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
E3D14_07160	ENOG4107U53	septum site-determining protein minD
E3D14_07200	ENOG4105C0A	alcohol dehydrogenase
E3D14_07205	ENOG4107SXA	Phosphorylase
E3D14_07210	ENOG4105D3G	Pseudouridine synthase
E3D14_07215	ENOG4105DU0	nucleoside hydrolase
E3D14_07230	ENOG4105RX8	Protein of unknown function (DUF1523)
E3D14_07235	ENOG4108N3W	hemolysin secretion protein
E3D14_07240	ENOG410829K	Lysine exporter protein (Lyse ygga)
E3D14_07260	ENOG4105C3N	Participates in control of cell volume in low-osmolarity conditions (By similarity)
E3D14_07275	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
E3D14_07280	ENOG4105KUZ	arsenate reductase
E3D14_07300	ENOG4105DS2	Anaerobic c4-dicarboxylate transporter
E3D14_07305	ENOG4105C5S	asparaginyl-tRNA synthetase
E3D14_07320	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
E3D14_07325	ENOG4105CZF	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism (By similarity)
E3D14_07330	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
E3D14_07335	ENOG410626R	Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity)
E3D14_07340	ENOG4105E78	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity)
E3D14_07345	ENOG4105D0M	Protease HtpX homolog
E3D14_07350	ENOG4107SDU	Methyl-accepting chemotaxis
E3D14_07355	ENOG4105QVC	MOSC domain-containing protein
E3D14_07355	ENOG4105QVC	MOSC domain-containing protein
E3D14_07370	ENOG4105Z2P	Protein of unknown function (DUF465)
E3D14_07380	ENOG4105UQX	Mate efflux family protein
E3D14_07400	ENOG4105C6T	cysteine synthase
E3D14_07420	ENOG4108RZE	Tetr family transcriptional regulator
E3D14_07425	ENOG4107RGH	Aldehyde dehydrogenase
E3D14_07435	ENOG4108QBX	(LipO)protein
E3D14_07445	ENOG4105C5Q	Transcriptional regulator
E3D14_07455	ENOG4105D3R	alkyl hydroperoxide reductase
E3D14_07475	ENOG4105PFA	Catalyzes the conversion of 5-hydroxyuridine (ho5U) to 5-methoxyuridine (mo5U) at position 34 in tRNA (By similarity)
E3D14_07480	ENOG4105DA6	Catalyzes the conversion of 5-methoxyuridine (mo5U) to uridine-5-oxyacetic acid (cmo5U) at position 34 in tRNA. May also participate in the methylation of uridine-5-oxyacetic acid (cmo5U) to uridine-5-oxyacetic acid methyl ester (mcmo5U) (By similarity)
E3D14_07490	ENOG4105C9M	aspartyl-trna synthetase
E3D14_07495	ENOG4105CDY	transcriptional regulatory protein
E3D14_07500	ENOG4105DIJ	Phosphoethanolamine transferase
E3D14_07515	ENOG4105CEY	Amp-dependent synthetase and ligase
E3D14_07525	ENOG4105D70	Integrase catalytic subunit
E3D14_07530	ENOG4105F5W	AtP-binding protein
E3D14_07555	ENOG4108JA1	polyketide synthase
E3D14_07570	ENOG4107T8Q	Glycosyl transferase (Group 1
E3D14_07600	ENOG4105E2R	ROK family
E3D14_07605	ENOG4105CE4	GlcNAc 6-P deacetylase
E3D14_07610	ENOG4105CKA	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion (By similarity)
E3D14_07615	ENOG4105CI1	PTS System
E3D14_07620	ENOG4105E2D	ec 3.2.1.52
E3D14_07625	ENOG4105CX6	glutaminyL-tRNA synthetase
E3D14_07630	ENOG41090R7	Ferric uptake
E3D14_07640	ENOG4105MHQ	Low-potential electron donor to a number of redox enzymes (By similarity)
E3D14_07645	ENOG4105NNH	LexA regulated protein
E3D14_07655	ENOG4105EV9	Alpha Beta Hydrolase
E3D14_07660	ENOG4107CDU	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated (By similarity)
E3D14_07665	ENOG4107QIX	Phosphoglucomutase (EC 5.4.2.2
E3D14_07680	ENOG4105CVE	Lytic murein transglycosylase
E3D14_07685	ENOG4108T9J	Cdp-alcohol phosphatidyltransferase
E3D14_07690	ENOG4108VGW	abc transporter atp-binding protein
E3D14_07695	ENOG4105CXZ	ABC transporter, permease
E3D14_07700	ENOG4105VNH	ABC transporter solute-binding protein
E3D14_07710	ENOG4107ZN8	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity (By similarity)
E3D14_07720	ENOG4107R50	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
E3D14_07725	ENOG4105KQ5	peptidylprolyl cis-trans isomerase
E3D14_07740	ENOG4105CFU	surface antigen
E3D14_07745	ENOG4105MA0	exported protein
E3D14_07760	ENOG4108WPH	sigma 54 modulation protein ribosomal protein S30EA
E3D14_07765	ENOG4105BZU	Histidine kinase
E3D14_07770	ENOG4107SC1	transglycosylase
E3D14_07775	ENOG41060NJ	transcriptional regulator
E3D14_07785	ENOG4105NAU	thioesterase Superfamily protein
E3D14_07800	ENOG4105E9H	Lytic Murein transglycosylase
E3D14_07805	ENOG4108RW0	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
E3D14_07810	ENOG4105D1A	Methyltransferase
E3D14_07815	ENOG4108UMW	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
E3D14_07820	ENOG4107RZZ	dna polymerase iii epsilon subunit
E3D14_07830	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
E3D14_07835	ENOG4107QPN	acyl-Coa dehydrogenase
E3D14_07840	ENOG4105F55	Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate (By similarity)
E3D14_07845	ENOG4105E7A	Glutamine amidotransferase
E3D14_07855	ENOG4105CHW	UPF0052 protein
E3D14_07865	ENOG4105BZU	Histidine kinase
E3D14_07875	ENOG4105WH1	Two component transcriptional regulator luxr family
E3D14_07880	ENOG4105BZU	Histidine kinase
E3D14_07885	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
E3D14_07900	ENOG4107QIW	Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity)
E3D14_07905	ENOG4108BGM	Quinol dehydrogenase periplasmic component
E3D14_07910	ENOG4105GXZ	Ferredoxin-type protein NapH
E3D14_07920	ENOG4105CUW	cytochrome C-TYPE protein
E3D14_07925	ENOG4108RIR	Molybdenum cofactor biosynthesis protein
E3D14_07930	ENOG4108YXW	Together with MoaA, is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
E3D14_07935	ENOG4105M00	molybdopterin converting factor, subunit 1
E3D14_07940	ENOG4108ZAF	Molybdopterin
E3D14_07945	ENOG4108S6J	ABC transporter, periplasmic molybdate-binding protein
E3D14_07950	ENOG4105E0C	molybdate abc transporter
E3D14_07955	ENOG4105CGB	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system (By similarity)
E3D14_07975	ENOG4105QYK	bacteriophage lambda Bor protein homolog
E3D14_07980	ENOG4105QYK	bacteriophage lambda Bor protein homolog
E3D14_07985	ENOG4105D06	uba thif-type nad fad binding protein
E3D14_07990	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
E3D14_07995	ENOG4105EUJ	GTP cyclohydrolase i
E3D14_08000	ENOG4105C8Q	Methyl-accepting chemotaxis
E3D14_08005	ENOG4105CKU	formyltetrahydrofolate synthetase
E3D14_08015	ENOG4105CC0	LysR family Transcriptional regulator
E3D14_08020	ENOG4108YYC	ycei family
E3D14_08045	ENOG4105D42	Cleaves the N-terminal amino acid of tripeptides (By similarity)
E3D14_08055	ENOG4105DP5	Catalyzes the biosynthesis of agmatine from arginine (By similarity)
E3D14_08085	ENOG4105I9P	Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor (By similarity)
E3D14_08095	ENOG4105D82	Glutamate dehydrogenase
E3D14_08100	ENOG4105FE9	pseudouridine synthase
E3D14_08105	ENOG4105DJ2	Major Facilitator Superfamily
E3D14_08125	ENOG4106428	Protein of unknown function (DUF2496)
E3D14_08135	ENOG4108Q2J	Inner membrane protein YebE
E3D14_08140	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
E3D14_08145	ENOG4105C4M	(Ubiquinol oxidase) subunit I
E3D14_08150	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
E3D14_08160	ENOG4105F27	Major Facilitator
E3D14_08165	ENOG4105CV8	reductase
E3D14_08170	ENOG41067V3	Antibiotic biosynthesis monooxygenase
E3D14_08195	ENOG4105HEI	LysR family (Transcriptional regulator
E3D14_08200	ENOG4108JQ0	Key enzyme in the regulation of glycerol uptake and metabolism (By similarity)
E3D14_08205	ENOG4105D8C	Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity)
E3D14_08210	ENOG4105CXY	transporter
E3D14_08215	ENOG4105E98	transcriptional regulator DeoR family
E3D14_08225	ENOG4105C6V	Glycerol-3-phosphate dehydrogenase
E3D14_08230	ENOG4106MZZ	glycerophosphoryl diester phosphodiesterase
E3D14_08235	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
E3D14_08250	ENOG4108WFC	UPF0438 protein yifE
E3D14_08255	ENOG4108QSZ	General inhibitor of pancreatic serine proteases inhibits chymotrypsin, trypsin, elastases, factor X, kallikrein as well as a variety of other proteases (By similarity)
E3D14_08275	ENOG4105CUG	Oligopeptidase b
E3D14_08280	ENOG4105D05	Receptor
E3D14_08285	ENOG4105E68	Sulfatase
E3D14_08290	ENOG4105PAN	UPF0352 protein
E3D14_08295	ENOG4106V8H	Nucleoid-associated protein
E3D14_08300	ENOG4107FKK	extracellular solute-binding protein family 1
E3D14_08305	ENOG4105D56	permease protein
E3D14_08310	ENOG4105EG2	ABC transporter, permease
E3D14_08315	ENOG4108IJ9	(ABC) transporter
E3D14_08320	ENOG4105CSR	polyphosphate kinase 2
E3D14_08330	ENOG4105C02	permease
E3D14_08335	ENOG41082K8	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Interacts with IscS and stimulates its activity. Then, accepts a sulfur from IscS and transfers it in turn to TusD (By similarity)
E3D14_08340	ENOG4105ERG	peptidase m48, ste24p
E3D14_08350	ENOG4105K89	arsenate reductase
E3D14_08360	ENOG4108ZYK	Acyl carrier protein phosphodiesterase
E3D14_08365	ENOG4105DWU	Membrane
E3D14_08370	ENOG4108JEH	abc transporter atp-binding protein
E3D14_08375	ENOG4106PMH	Extracellular solute-binding protein family 3
E3D14_08380	ENOG4105DSP	amino acid AbC transporter
E3D14_08400	ENOG4105F1A	Pyruvate formate-lyase
E3D14_08405	ENOG4105BZU	Histidine kinase
E3D14_08415	ENOG4105DN3	alpha-2-macroglobulin domain protein
E3D14_08420	ENOG4108JQB	penicillin-binding protein 1C
E3D14_08430	ENOG4107R08	Integrase
E3D14_08480	ENOG4105DH7	May be involved in recombination (By similarity)
E3D14_08515	ENOG41076J9	exonuclease VIII
E3D14_08615	ENOG4105NY2	NinB protein
E3D14_08775	ENOG4105D8I	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS (By similarity)
E3D14_08785	ENOG4105EN6	Membrane
E3D14_08790	ENOG4105I03	Flagellin
E3D14_08810	ENOG4105MQ3	flagellar protein FliS
E3D14_08825	ENOG4105JKQ	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Binds vitamin B12 and delivers it to the periplasmic surface of BtuC (By similarity)
E3D14_08835	ENOG4105DUF	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively (By similarity)
E3D14_08850	ENOG4108NVR	Methyl-accepting chemotaxis
E3D14_08865	ENOG4105CYM	Glutathione S-transferase
E3D14_08875	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
E3D14_08880	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
E3D14_08885	ENOG4108RZA	ABC transporter
E3D14_08890	ENOG4105E5M	Multidrug resistance protein D
E3D14_08895	ENOG4105EJC	lysr family transcriptional regulator
E3D14_08900	ENOG4107H9G	Necessary for formate dehydrogenase activity (By similarity)
E3D14_08915	ENOG4107YUN	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division (By similarity)
E3D14_08925	ENOG4105D0A	hydroxylase
E3D14_08930	ENOG4105EAK	ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family
E3D14_08935	ENOG4105D43	The glycine cleavage system catalyzes the degradation of glycine (By similarity)
E3D14_08940	ENOG4105KE9	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity)
E3D14_08945	ENOG4105CBI	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
E3D14_08965	ENOG4105D3R	alkyl hydroperoxide reductase
E3D14_08970	ENOG4105W87	Cbs domain
E3D14_08975	ENOG4105E2N	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) (By similarity)
E3D14_08980	ENOG4105C6U	Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity)
E3D14_08985	ENOG4105VIE	preprotein translocase, subunit YajC
E3D14_08990	ENOG4107QN8	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
E3D14_08995	ENOG4107RAB	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
E3D14_09000	ENOG4105KHC	sulfurtransferase
E3D14_09010	ENOG4106RZ4	Peptidase U32
E3D14_09015	ENOG4105CFP	Peptidase U32
E3D14_09020	ENOG4105XPQ	lipid carrier protein
E3D14_09030	ENOG4105CVS	RNA methyltransferase TrmH family, group 1
E3D14_09040	ENOG4105C3J	Cysteine desulfurase
E3D14_09045	ENOG4107XTC	May be involved in the formation or repair of Fe-S clusters present in iron-sulfur proteins
E3D14_09050	ENOG4108Z4V	iron-sulfur cluster assembly
E3D14_09055	ENOG4108SWN	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA (By similarity)
E3D14_09060	ENOG4105C9I	Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB
E3D14_09065	ENOG4108ZIT	Ferredoxin, 2FE-2S
E3D14_09075	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
E3D14_09080	ENOG4108UGX	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity)
E3D14_09085	ENOG4105C55	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
E3D14_09095	ENOG4105HSZ	Cytoskeletal protein that is involved in cell-shape control through regulation of the length of the long axis (By similarity)
E3D14_09100	ENOG4105C4E	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (By similarity)
E3D14_09105	ENOG4105CUT	histidyl-tRNA synthetase
E3D14_09110	ENOG4105N21	Membrane
E3D14_09115	ENOG4105CNE	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
E3D14_09120	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
E3D14_09125	ENOG4105VPD	cellular component movement
E3D14_09130	ENOG4105CHQ	Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella (By similarity)
E3D14_09135	ENOG4107QIK	phosphoribosylformylglycinamidine synthase
E3D14_09145	ENOG4105CKW	Inner membrane protein yedI
E3D14_09155	ENOG4105DPN	Oligoendopeptidase f
E3D14_09165	ENOG4105CEP	NADH dehydrogenase
E3D14_09170	ENOG4105K8R	UPF0145 protein
E3D14_09180	ENOG4105EBE	Peptidase U61, LD-carboxypeptidase A
E3D14_09185	ENOG4107T7U	Sulfatase
E3D14_09195	ENOG4105CFH	Aspartokinase
E3D14_09200	ENOG4107QZM	n-acetylglutamate synthase
E3D14_09205	ENOG4107QXP	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
E3D14_09250	ENOG4108302	MgtC SapB transporter
E3D14_09340	ENOG4105C85	amino acid
E3D14_09350	ENOG4105CF9	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation (By similarity)
E3D14_09355	ENOG4108HRN	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate (By similarity)
E3D14_09395	ENOG4105D01	(LipO)protein
E3D14_09400	ENOG4105EYK	Phosphatidylglycerophosphatase B
E3D14_09405	ENOG4105CJ0	Catalyzes the oxidation of erythronate-4-phosphate to 3- hydroxy-2-oxo-4-phosphonooxybutanoate (By similarity)
E3D14_09410	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
E3D14_09420	ENOG4105DI7	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity)
E3D14_09425	ENOG4107QTG	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA (By similarity)
E3D14_09430	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
E3D14_09435	ENOG4108S3P	Sporulation domain protein
E3D14_09440	ENOG4108Z0T	Part of a sulfur-relay system (By similarity)
E3D14_09445	ENOG4105EM2	membrane
E3D14_09450	ENOG4108MN8	Membrane
E3D14_09460	ENOG4107RHT	methyl-accepting chemotaxis sensory transducer with Pas Pac sensor
E3D14_09470	ENOG4108W1A	pseudouridine synthase
E3D14_09480	ENOG4105E6K	4-Hydroxyphenylpyruvate dioxygenase
E3D14_09495	ENOG4108RXX	maleylacetoacetate isomerase
E3D14_09500	ENOG4108TGY	Glutathione S-transferase
E3D14_09520	ENOG4105CAQ	asparagine synthetase
E3D14_09530	ENOG4105CKD	glutathione-regulated potassium-efflux system protein
E3D14_09535	ENOG4105D4U	had-superfamily hydrolase, subfamily iia
E3D14_09540	ENOG4105EKD	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism (By similarity)
E3D14_09545	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
E3D14_09550	ENOG4105EE5	Membrane protein terC
E3D14_09560	ENOG4105CQB	FAD linked oxidase domain protein
E3D14_09570	ENOG4105KA0	thioesterase Superfamily protein
E3D14_09575	ENOG4105C1J	atp-dependent rna helicase
E3D14_09585	ENOG4105BZU	Histidine kinase
E3D14_09590	ENOG4105D3Y	Na H antiporter
E3D14_09595	ENOG4105DH5	Responsible for the end-turnover of tRNA specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis (By similarity)
E3D14_09605	ENOG4105EIY	sodium-type flagellar protein motY
E3D14_09610	ENOG4108UYE	Lactoylglutathione lyase
E3D14_09615	ENOG4105CSM	endonuclease III
E3D14_09620	ENOG4105DZB	Electron transport complex
E3D14_09625	ENOG4108UQQ	Electron transport complex
E3D14_09630	ENOG4105D6A	Electron transport complex
E3D14_09640	ENOG4108R3D	Electron transport complex
E3D14_09645	ENOG4105DGN	Electron transport complex
E3D14_09650	ENOG4108PCN	EamA-like transporter family
E3D14_09690	ENOG4105CHH	sulfate transporter
E3D14_09760	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
E3D14_09825	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
E3D14_09830	ENOG4105VEQ	Cold shock protein
E3D14_09835	ENOG4105KAE	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation (By similarity)
E3D14_09840	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
E3D14_09845	ENOG4105K9U	however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity)
E3D14_09850	ENOG4105DWA	May conjugate Arg from its aminoacyl-tRNA to the N- termini of proteins containing an N-terminal aspartate or glutamate
E3D14_09855	ENOG4108R4Z	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine (By similarity)
E3D14_09860	ENOG4107MBR	17 kDa surface antigen
E3D14_09865	ENOG4105BZU	Histidine kinase
E3D14_09870	ENOG4105C3M	thioredoxin reductase
E3D14_09885	ENOG4105EW9	transcriptional regulator AsnC family
E3D14_09890	ENOG4105CNU	cell division protein FtsK
E3D14_09895	ENOG4107Y7W	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) (By similarity)
E3D14_09900	ENOG4105D1H	recombination factor protein RarA
E3D14_09905	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
E3D14_09910	ENOG4105E96	Colicin v production protein
E3D14_09915	ENOG4105CBA	glutamine phosphoribosylpyrophosphate amidotransferase
E3D14_09925	ENOG4108JQ2	peptide transport system atp-binding protein
E3D14_09930	ENOG4108JQ3	Peptide ABC transporter ATP-binding protein
E3D14_09935	ENOG4108EU3	peptide transport system, permease
E3D14_09940	ENOG4108I5W	peptide transport system, permease protein
E3D14_09945	ENOG4108J59	Extracellular solute-binding protein, family 5
E3D14_09950	ENOG4105E51	psp operon transcriptional activator
E3D14_09955	ENOG41087YS	Phage shock protein A
E3D14_09960	ENOG4105YYT	phage shock protein B
E3D14_09970	ENOG4105CM6	amino acid regulated cytosolic protein
E3D14_09975	ENOG4106K28	UPF0283 membrane protein
E3D14_09980	ENOG4105MIR	Phenylalanine 4-monooxygenase
E3D14_09985	ENOG41090A4	Pterin carbinolamine dehydratase
E3D14_09995	ENOG4108WS1	
E3D14_10000	ENOG4108KHX	Diguanylate cyclase
E3D14_10005	ENOG4105UYK	outer membrane protein a
E3D14_10010	ENOG4105EE5	Membrane protein terC
E3D14_10020	ENOG4105MH2	YfcL protein
E3D14_10025	ENOG4108IQE	Amp-dependent synthetase and ligase
E3D14_10030	ENOG4107T42	This enzyme scavenge exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis (By similarity)
E3D14_10035	ENOG41067MG	lrgb family
E3D14_10055	ENOG4105CJB	Exodeoxyribonuclease I
E3D14_10080	ENOG4105ETT	transcriptional Regulator, LysR family
E3D14_10085	ENOG4105CAC	Catalyzes the conversion of L-arabinose to L-ribulose (By similarity)
E3D14_10095	ENOG4105EF1	ribulokinase
E3D14_10100	ENOG4105DMK	Periplasmic binding protein LacI transcriptional regulator
E3D14_10105	ENOG4105C2J	ABC transporter
E3D14_10110	ENOG4105CNN	ABC, transporter
E3D14_10120	ENOG4105CRD	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P) (By similarity)
E3D14_10125	ENOG4105F0Z	galactose-1-phosphate uridylyltransferase
E3D14_10130	ENOG4105CMR	udp-glucose 4-epimerase
E3D14_10135	ENOG41060NJ	transcriptional regulator
E3D14_10140	ENOG4108KDD	Involved in the transport of maltose and maltodextrins (By similarity)
E3D14_10180	ENOG4107FKK	extracellular solute-binding protein family 1
E3D14_10190	ENOG4105EG2	ABC transporter, permease
E3D14_10200	ENOG4105C4C	beta-galactosidase
E3D14_10205	ENOG4105CI1	PTS System
E3D14_10210	ENOG4105CA9	Pyruvate kinase
E3D14_10220	ENOG4105NRA	50s ribosomal protein l31 type b
E3D14_10235	ENOG4108VKG	metal-dependent hydrolase
E3D14_10250	ENOG4105CEE	C4-dicarboxylate transporter
E3D14_10260	ENOG4105CWG	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34 (By similarity)
E3D14_10265	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
E3D14_10280	ENOG4105BZN	citrate synthase
E3D14_10285	ENOG4108UTY	succinate dehydrogenase, cytochrome b556 subunit
E3D14_10290	ENOG4105N1I	succinate dehydrogenase, hydrophobic membrane anchor protein
E3D14_10295	ENOG4105C00	Succinate dehydrogenase (Flavoprotein subunit)
E3D14_10300	ENOG4105E33	succinate dehydrogenase
E3D14_10305	ENOG4105C7P	2-oxoglutarate dehydrogenase, E1
E3D14_10310	ENOG4105C7S	Dehydrogenase
E3D14_10315	ENOG4105CMV	Succinyl-CoA synthetase subunit beta
E3D14_10320	ENOG4105CH8	Succinyl-CoA ligase ADP-forming subunit alpha
E3D14_10330	ENOG4105C6N	Formate acetyltransferase
E3D14_10335	ENOG4105TMB	Formate nitrite transporter
E3D14_10340	ENOG4105DDY	UPF0142 protein ycaO
E3D14_10345	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
E3D14_10365	ENOG4108RYK	Nad-dependent epimerase dehydratase
E3D14_10370	ENOG4105CR8	Transcriptional regulator
E3D14_10380	ENOG4105UEI	Transcriptional Regulator AraC Family
E3D14_10385	ENOG4105E0K	tonB-dependent siderophore receptor
E3D14_10395	ENOG4105DZ2	Transcriptional regulator
E3D14_10400	ENOG4105DSS	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation (By similarity)
E3D14_10425	ENOG4105MWK	D-amino acid dehydrogenase, small subunit
E3D14_10430	ENOG4105EXX	Deoxyribodipyrimidine photolyase-related protein
E3D14_10440	ENOG4105C0F	tryptophanase EC 4.1.99.1
E3D14_10445	ENOG41061WM	D-Alanyl-D-Alanine
E3D14_10455	ENOG4108DMF	Cytochrome C biogenesis protein
E3D14_10460	ENOG4107QX9	Thiol disulfide interChange protein
E3D14_10465	ENOG4105DA4	cytochrome c-type biogenesis protein
E3D14_10470	ENOG4105DVI	reductase, NrfD
E3D14_10475	ENOG4105D3S	4Fe-4S Ferredoxin, iron-sulfur binding domain protein
E3D14_10480	ENOG4105JJ8	Cytochrome c nitrite reductase, pentaheme subunit
E3D14_10490	ENOG4105CHG	glycolate oxidase (iron-sulfur subunit)
E3D14_10495	ENOG4108KJ0	anaerobic glycerol-3-phosphate dehydrogenase, subunit B
E3D14_10500	ENOG4107R5Y	anaerobic glycerol-3-phosphate dehydrogenase, subunit A
E3D14_10505	ENOG4105K5B	UPF0225 protein
E3D14_10510	ENOG4105C8Q	Methyl-accepting chemotaxis
E3D14_10515	ENOG4105E2R	ROK family
E3D14_10520	ENOG4105CEQ	signal transduction histidine kinase regulating citrate malate metabolism
E3D14_10525	ENOG4108MRH	transcriptional regulatory protein
E3D14_10545	ENOG4105CHQ	Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella (By similarity)
E3D14_10550	ENOG4105D0C	transport protein
E3D14_10565	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
E3D14_10575	ENOG4105DQR	SNARE associated Golgi
E3D14_10580	ENOG410635M	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein (By similarity)
E3D14_10585	ENOG4105DKR	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity)
E3D14_10590	ENOG4105C05	Multifunctional regulator of fatty acid metabolism (By similarity)
E3D14_10595	ENOG4105ED1	spovr family
E3D14_10605	ENOG4105CYN	Serine protein kinase
E3D14_10610	ENOG4105C9U	ATP-dependent DNA helicase RecQ
E3D14_10615	ENOG4107QV7	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system) (By similarity)
E3D14_10620	ENOG4105C44	Serine transporter
E3D14_10630	ENOG4105CRQ	synthase (Component I)
E3D14_10660	ENOG4107QQN	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties (By similarity)
E3D14_10665	ENOG4105C8P	)-transporter
E3D14_10670	ENOG4105K63	Thioredoxin
E3D14_10675	ENOG4105BZU	Histidine kinase
E3D14_10685	ENOG4105BZ1	(ABC) transporter
E3D14_10695	ENOG4105WQ3	Rna-binding protein
E3D14_10705	ENOG4105D1N	poly(r)-hydroxyalkanoic acid synthase, class
E3D14_10725	ENOG4107XGF	functions in a salvage pathway. Uses pyridoxamine (By similarity)
E3D14_10730	ENOG41061CK	Antibiotic biosynthesis monooxygenase
E3D14_10770	ENOG4105KK4	UPF0060 membrane protein
E3D14_10780	ENOG4105K5X	acetyltransferase
E3D14_10785	ENOG4105C1J	atp-dependent rna helicase
E3D14_10790	ENOG4108V06	Glutathione peroxidase
E3D14_10800	ENOG4105CPF	Cell wall formation (By similarity)
E3D14_10810	ENOG4106IUH	DTW domain containing protein
E3D14_10815	ENOG4105EJ9	Membrane
E3D14_10820	ENOG4105VP0	transcriptional regulator, lysR family
E3D14_10835	ENOG4105CPB	ATP-dependent endonuclease of the OLD family
E3D14_10875	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
E3D14_10880	ENOG4105PAD	Hydrolase
E3D14_10925	ENOG4105CTQ	phosphohexokinase
E3D14_10935	ENOG4107S90	membrAne
E3D14_10940	ENOG4106371	Methyltransferase
E3D14_10950	ENOG4105DAH	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF (By similarity)
E3D14_10955	ENOG4105DUC	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division (By similarity)
E3D14_10960	ENOG4105K6T	rare lipoprotein A
E3D14_11025	ENOG4108VWS	Yaeq family
E3D14_11045	ENOG4105EHG	Permease protein
E3D14_11065	ENOG4107MBR	17 kDa surface antigen
E3D14_11090	ENOG4105CBN	LysR family transcriptional regulator
E3D14_11095	ENOG4105EFU	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin (By similarity)
E3D14_11105	ENOG4105DUM	transcriptional regulator, lysR family
E3D14_11115	ENOG4105NWR	lipid A biosynthesis (Kdo)2-(Lauroyl)-lipid IVA acyltransferase
E3D14_11120	ENOG4105NWR	lipid A biosynthesis (Kdo)2-(Lauroyl)-lipid IVA acyltransferase
E3D14_11135	ENOG4105BZU	Histidine kinase
E3D14_11145	ENOG4105CQ2	DNA polymerase
E3D14_11170	ENOG4107QI1	Mate efflux family protein
E3D14_11175	ENOG4105W1I	UPF0253 protein
E3D14_11180	ENOG4108R6K	riboflavin synthase, subunit alpha
E3D14_11190	ENOG4107UW8	HAD-superfamily hydrolase subfamily IA variant 3
E3D14_11195	ENOG4108HH9	Catalyzes two reactions the first one is the production of beta-formyl glycinamide ribonucleotide (GAR) from formate, ATP and beta GAR
E3D14_11205	ENOG4108V3G	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity)
E3D14_11240	ENOG4105XW2	UPF0263 protein
E3D14_11245	ENOG4108VKV	Monofunctional biosynthetic peptidoglycan transglycosylase
E3D14_11255	ENOG4105VJP	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell (By similarity)
E3D14_11260	ENOG4107QMS	site-determining protein
E3D14_11265	ENOG4105K7U	Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization (By similarity)
E3D14_11270	ENOG4105VNG	YcgL domain-containing protein
E3D14_11275	ENOG4105CVE	Lytic murein transglycosylase
E3D14_11280	ENOG4105EJQ	L-serine dehydratase
E3D14_11290	ENOG4105EJQ	L-serine dehydratase
E3D14_11295	ENOG4105NBK	UPF0345 protein
E3D14_11300	ENOG4105CK2	sodium dicarboxylate symporter
E3D14_11310	ENOG4105CHU	acetyl-coa acetyltransferase
E3D14_11315	ENOG4105D58	Diguanylate phosphodiesterase
E3D14_11320	ENOG4105CKF	membrane protein involved in aromatic hydrocarbon degradation
E3D14_11325	ENOG4105CKF	membrane protein involved in aromatic hydrocarbon degradation
E3D14_11365	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
E3D14_11370	ENOG4105CHU	acetyl-coa acetyltransferase
E3D14_11375	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
E3D14_11380	ENOG4108Z8G	Alkylphosphonate utilization operon protein PhnA
E3D14_11400	ENOG4107R5U	Periplasmic binding protein LacI transcriptional regulator
E3D14_11405	ENOG4105C2J	ABC transporter
E3D14_11415	ENOG41062B0	ABC transporter, permease
E3D14_11425	ENOG4105K3G	Periplasmic Protein
E3D14_11490	ENOG4105D29	Helix-turn-helix type 11 domain protein
E3D14_11500	ENOG4105K8F	Phosphoribosyl-amp cyclohydrolase
E3D14_11505	ENOG4105C0S	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity)
E3D14_11510	ENOG4105BZU	Histidine kinase
E3D14_11520	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
E3D14_11525	ENOG4105CJV	Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase
E3D14_11530	ENOG4108UJE	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity)
E3D14_11535	ENOG4105ECC	imidazole-glycerol-phosphate dehydratase
E3D14_11540	ENOG4105CIH	Imidazole acetol-phosphate transaminase
E3D14_11545	ENOG4105CEK	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity)
E3D14_11550	ENOG4105E21	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity)
E3D14_11560	ENOG4105DVT	helicase
E3D14_11565	ENOG41072GX	Peptidase M22 Glycoprotease
E3D14_11575	ENOG4108MXF	Alpha Beta Hydrolase
E3D14_11580	ENOG4105CEY	Amp-dependent synthetase and ligase
E3D14_11600	ENOG4105FBT	Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs (By similarity)
E3D14_11605	ENOG4105WD1	Membrane
E3D14_11610	ENOG4109003	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity)
E3D14_11615	ENOG4107QMP	dna polymerase iii subunits gamma and tau
E3D14_11620	ENOG4105KDX	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection (By similarity)
E3D14_11625	ENOG4105DWD	nucleoside recognition domain protein
E3D14_11630	ENOG4105WH1	Two component transcriptional regulator luxr family
E3D14_11640	ENOG4105CQ7	ATP-dependent helicase
E3D14_11650	ENOG4105KW6	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance (By similarity)
E3D14_11655	ENOG4105C5X	domain protein
E3D14_11660	ENOG4105CR7	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA (By similarity)
E3D14_11665	ENOG4105D4F	Synthesizes selenophosphate from selenide and ATP (By similarity)
E3D14_11675	ENOG4105FAT	Acyl-transferase
E3D14_11680	ENOG4105DR4	Methyltransferase
E3D14_11690	ENOG4105VSY	K01512 acylphosphatase EC 3.6.1.7
E3D14_11700	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
E3D14_11705	ENOG4105D1F	ATP-binding protein
E3D14_11710	ENOG4105DBI	uridine monophosphokinase
E3D14_11715	ENOG4105DHP	deoxycytidine triphosphate deaminase
E3D14_11720	ENOG4105CJ3	phosphate transporter
E3D14_11725	ENOG4105C03	ribonuclease
E3D14_11730	ENOG4105EI2	Pseudouridine synthase
E3D14_11735	ENOG4108YZS	Had-superfamily hydrolase, subfamily ia, variant 1
E3D14_11740	ENOG4108UHJ	MAF-like protein
E3D14_11745	ENOG4105FCQ	metal-binding, possibly nucleic acid-binding protein
E3D14_11750	ENOG4105VGS	50s ribosomal protein l32
E3D14_11755	ENOG4105C6B	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA (By similarity)
E3D14_11760	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
E3D14_11765	ENOG4105CJF	Malonyl coA-acyl carrier protein transacylase
E3D14_11770	ENOG4105CHR	reductase
E3D14_11775	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
E3D14_11780	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
E3D14_11785	ENOG4105YAZ	4-amino-4-deoxychorismate lyase
E3D14_11790	ENOG4105HHA	aminodeoxychorismate lyase
E3D14_11795	ENOG4108ZMD	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity)
E3D14_11800	ENOG4107QRG	dna polymerase iii
E3D14_11805	ENOG4105F8V	Hydrolase, tatD family
E3D14_11820	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
E3D14_11830	ENOG4105F1S	paraquat-inducible protein a
E3D14_11840	ENOG4105CR4	methylisocitrate lyase
E3D14_11850	ENOG4105DXD	2-methylcitrate dehydratase
E3D14_11890	ENOG4105PDP	Short chain dehydrogenase
E3D14_11965	ENOG4105MQ5	zona occludens toxin
E3D14_11975	ENOG4105F5W	AtP-binding protein
E3D14_12040	ENOG4105MQ5	zona occludens toxin
E3D14_12055	ENOG4105DAN	ATP-dependent protease
E3D14_12060	ENOG4108RKI	Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl- ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)- decenoyl-ACP. Can catalyze the dehydratase reaction for beta- hydroxyacyl-ACPs with saturated chain lengths up to 16 0, being most active on intermediate chain length (By similarity)
E3D14_12065	ENOG4105WFT	During stationary phase, converts 70S ribosomes to an inactive dimeric form (100S ribosomes) (By similarity)
E3D14_12075	ENOG4105C5H	ABC transporter
E3D14_12085	ENOG4105C4H	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA (By similarity)
E3D14_12090	ENOG4108T7E	Contributes to the efficiency of the cell division process by stabilizing the polymeric form of the cell division protein FtsZ. Acts by promoting interactions between FtsZ protofilaments and suppressing the GTPase activity of FtsZ (By similarity)
E3D14_12095	ENOG4107QYT	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor (By similarity)
E3D14_12100	ENOG4105C7I	Dehydrogenase
E3D14_12110	ENOG4105CD8	aminopeptidase N
E3D14_12115	ENOG4105CN1	protease
E3D14_12120	ENOG41073DY	may be a structural element that influences the osmotic activation of ProP at a post-translational level (By similarity)
E3D14_12125	ENOG4108ZGC	gaf domain protein
E3D14_12135	ENOG4105EUH	cytochrome C oxidase, cbb3-type, subunit i
E3D14_12150	ENOG4105D6P	C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex (By similarity)
E3D14_12160	ENOG4105C59	p-type ATPase
E3D14_12175	ENOG4105DS0	Transcriptional regulator, Crp Fnr family
E3D14_12180	ENOG4105Q9Y	Universal stress protein
E3D14_12185	ENOG4105CB3	Required for the thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32) (By similarity)
E3D14_12200	ENOG4108K3A	Glutathione S-transferase
E3D14_12205	ENOG4105MRB	Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose (By similarity)
E3D14_12215	ENOG4105CNN	ABC, transporter
E3D14_12220	ENOG4105E9V	Periplasmic binding protein LacI transcriptional regulator
E3D14_12225	ENOG4108RVA	ribokinase
E3D14_12230	ENOG4105ETE	Transcriptional regulator (LacI family
E3D14_12235	ENOG4108KHX	Diguanylate cyclase
E3D14_12245	ENOG4105NDF	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity)
E3D14_12265	ENOG4108ZUF	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
E3D14_12270	ENOG4105C6A	phenylalanyl-tRNA synthetase (beta subunit)
E3D14_12275	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
E3D14_12280	ENOG4108YZX	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity)
E3D14_12290	ENOG4108UUX	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity)
E3D14_12295	ENOG4105C22	threonyL-tRNA synthetase
E3D14_12310	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
E3D14_12315	ENOG4108HWB	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
E3D14_12320	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
E3D14_12325	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
E3D14_12330	ENOG4105E05	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
E3D14_12335	ENOG4105XPH	Ferredoxin
E3D14_12340	ENOG4105CA3	membrane-bound lytic murein transglycosylase
E3D14_12345	ENOG4105XZD	Fe-S protein
E3D14_12350	ENOG4105DM4	PTS System
E3D14_12355	ENOG4105DE4	1-phosphofructokinase
E3D14_12360	ENOG4105DTZ	bifunctional PTS system fructose-specific transporter subunit IIA HPr protein
E3D14_12365	ENOG4107B7Y	DNA-binding transcriptional regulator FruR
E3D14_12370	ENOG4105E0U	tyrosine-specific transport protein
E3D14_12385	ENOG4105C1J	atp-dependent rna helicase
E3D14_12395	ENOG4105D10	5-enolpyruvylshikimate-3-phosphate phospholyase
E3D14_12400	ENOG4105C76	Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue (By similarity)
E3D14_12405	ENOG4108DG9	Smr protein MutS2
E3D14_12410	ENOG4105BZU	Histidine kinase
E3D14_12460	ENOG4105HF0	Membrane
E3D14_12465	ENOG4105D5Q	Arginine ornithine antiporter
E3D14_12470	ENOG4105CHR	reductase
E3D14_12475	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
E3D14_12480	ENOG4105E39	Enoyl-CoA hydratase
E3D14_12485	ENOG4105E39	Enoyl-CoA hydratase
E3D14_12490	ENOG4105C1G	acyl-Coa dehydrogenase
E3D14_12495	ENOG4105C26	Dehydrogenase
E3D14_12500	ENOG4105C1G	acyl-Coa dehydrogenase
E3D14_12505	ENOG4107QX3	carboxylase
E3D14_12510	ENOG4105E39	Enoyl-CoA hydratase
E3D14_12540	ENOG4106HK8	GPR1 FUN34 yaaH family protein
E3D14_12550	ENOG410849A	acetyltransferase, (GNAT) family
E3D14_12555	ENOG4105BZG	amino acid carrier protein
E3D14_12560	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
E3D14_12575	ENOG41062QD	Membrane
E3D14_12580	ENOG4107QN1	sodium solute
E3D14_12585	ENOG4105C5H	ABC transporter
E3D14_12590	ENOG4105EIN	peptidylprolyl cis-trans isomerase
E3D14_12595	ENOG4105K70	DNA-binding protein
E3D14_12600	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
E3D14_12605	ENOG4105CHN	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
E3D14_12610	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
E3D14_12615	ENOG4105DEA	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation
E3D14_12635	ENOG4105D60	lipoprotein releasing system transmembrane protein
E3D14_12640	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
E3D14_12645	ENOG4105D60	lipoprotein releasing system transmembrane protein
E3D14_12655	ENOG4108JA2	transcriptioN-repair coupling factor
E3D14_12660	ENOG4105CZI	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
E3D14_12665	ENOG4108J59	Extracellular solute-binding protein, family 5
E3D14_12670	ENOG4108IPJ	Membrane
E3D14_12680	ENOG4108BY2	phosphohistidine phosphatase
E3D14_12685	ENOG4107QXK	peptidase
E3D14_12690	ENOG4105FQ6	thiopurine methyltransferase
E3D14_12720	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
E3D14_12725	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
E3D14_12740	ENOG4105SG9	biopolymer transport protein, ExbD
E3D14_12745	ENOG4105DS1	cytochrome b561
E3D14_12750	ENOG4105DVS	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
E3D14_12755	ENOG4105D4P	Coproporphyrinogen iii oxidase
E3D14_12765	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
E3D14_12770	ENOG4105CMY	5-enolpyruvylshikimate-3-phosphate synthase
E3D14_12775	ENOG4107QM1	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine (By similarity)
E3D14_12780	ENOG4105C10	Electron transfer flavoprotein
E3D14_12785	ENOG4105BZJ	Electron transfer flavoprotein
E3D14_12790	ENOG4105DWH	electron transfer flavoprotein-ubiquinone oxidoreductase
E3D14_12795	ENOG4105DWH	electron transfer flavoprotein-ubiquinone oxidoreductase
E3D14_12800	ENOG4107QUT	magnesium and cobalt transport protein CorA
E3D14_12805	ENOG4105QZU	Inner membrane protein YfeZ
E3D14_12820	ENOG4105D05	Receptor
E3D14_12825	ENOG4105DQ5	transport system permease protein
E3D14_12830	ENOG4105TVJ	transport system, permease
E3D14_12835	ENOG4105E0A	ABC, transporter
E3D14_12840	ENOG4108TSE	Transferase
E3D14_12845	ENOG4108MES	Periplasmic binding protein
E3D14_12850	ENOG4105C0W	non-ribosomal peptide synthetase
E3D14_12860	ENOG4105X17	23-dihydro-2,3-dihydroxybenzoate dehydrogenase
E3D14_12865	ENOG4105CEY	Amp-dependent synthetase and ligase
E3D14_12870	ENOG4105WQI	isochorismatase
E3D14_12875	ENOG4108IQC	2,3-dihydroxybenzoate-AMP ligase
E3D14_12885	ENOG4105F3T	(LipO)protein
E3D14_12895	ENOG4107QQ4	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans (By similarity)
E3D14_12900	ENOG4105BZU	Histidine kinase
E3D14_12915	ENOG4105C8Q	Methyl-accepting chemotaxis
E3D14_12920	ENOG4107RE1	Inosine-guanosine kinase
E3D14_12925	ENOG4105WJG	Glutathione
E3D14_12930	ENOG4105CFX	Catalyzes the ferrous insertion into protoporphyrin IX (By similarity)
E3D14_12935	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
E3D14_12945	ENOG4105CJX	Molecular chaperone. Has ATPase activity (By similarity)
E3D14_12950	ENOG4105F3K	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity)
E3D14_12955	ENOG4107H9G	Necessary for formate dehydrogenase activity (By similarity)
E3D14_12975	ENOG4108RC0	Electron transport protein
E3D14_12995	ENOG4105DFH	Transport of potassium into the cell (By similarity)
E3D14_13000	ENOG4108MFN	small subunit of hydrogenase-3, iron-sulfur protein (part of formate hydrogenlyase (FHL) complex)
E3D14_13005	ENOG4108JPZ	Monovalent cation H antiporter subunit D
E3D14_13010	ENOG4107TDF	Formate hydrogenlyase subunit 4
E3D14_13015	ENOG4105CQV	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
E3D14_13025	ENOG4105C47	NADH ubiquinone oxidoreductase 20 kda subunit
E3D14_13030	ENOG4105I6X	formate hydrogenlyase maturation
E3D14_13035	ENOG4108MG9	hydrogenase 3 maturation protease
E3D14_13040	ENOG4105C1Y	Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis (By similarity)
E3D14_13045	ENOG4105EM7	Selenocysteine-specific translation elongation factor
E3D14_13055	ENOG4105WRB	Hydrogenase assembly chaperone hypC hupF
E3D14_13060	ENOG4105CQS	hydrogenase expression formation protein HypD
E3D14_13065	ENOG4105C45	hydrogenase expression formation protein (HypE)
E3D14_13070	ENOG4105WMM	Probably plays a role in a hydrogenase nickel cofactor insertion step (By similarity)
E3D14_13075	ENOG4107RSS	Hydrogenase accessory protein HypB
E3D14_13080	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
E3D14_13090	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
E3D14_13095	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
E3D14_13105	ENOG4108WGS	hydrogenase 2-specific chaperone
E3D14_13110	ENOG4108USZ	hydrogenase
E3D14_13115	ENOG4105DPX	Hydrogenase, large subunit
E3D14_13120	ENOG4105CJ5	hydrogenase 2 b cytochrome subunit
E3D14_13125	ENOG4105QA4	4Fe-4S Ferredoxin, iron-sulfur binding domain protein
E3D14_13130	ENOG4105E3S	small subunit
E3D14_13135	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
E3D14_13150	ENOG4108RMJ	sensory transduction regulator
E3D14_13160	ENOG4107104	thymidine kinase
E3D14_13165	ENOG4107S6Z	Na H antiporter
E3D14_13180	ENOG4108WBT	adenosyltransferase
E3D14_13185	ENOG4105VRT	cytoplasmic protein
E3D14_13190	ENOG4105EIZ	Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity)
E3D14_13195	ENOG4105FD2	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) (By similarity)
E3D14_13210	ENOG4106EG9	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) (By similarity)
E3D14_13215	ENOG4105CFV	Tetratricopeptide repeat protein
E3D14_13225	ENOG41080YA	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
E3D14_13230	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
E3D14_13235	ENOG4105CAT	Cytidine monophosphate kinase
E3D14_13240	ENOG4108JEN	Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate (By similarity)
E3D14_13245	ENOG4107R11	Transcriptional regulator
E3D14_13250	ENOG4105CMU	LysR family (Transcriptional regulator
E3D14_13255	ENOG4108SC4	)-transporter
E3D14_13270	ENOG4108DBC	nitroreductase
E3D14_13275	ENOG4105BZU	Histidine kinase
E3D14_13290	ENOG4105CBN	LysR family transcriptional regulator
E3D14_13295	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
E3D14_13310	ENOG4108RU0	short-chain dehydrogenase reductase
E3D14_13320	ENOG4107RGM	aldo keto reductase
E3D14_13325	ENOG4105VFU	Rna-binding protein
E3D14_13335	ENOG4105CDA	abc transporter atp-binding protein
E3D14_13340	ENOG4105EAD	ABC transporter
E3D14_13345	ENOG4106TNF	Periplasmic binding protein
E3D14_13350	ENOG4105EZ7	amino acid ABC transporter
E3D14_13355	ENOG4105HPZ	Involved in the removal of murein from the sacculus. May also facilitate integration of nascent murein strands into the sacculus by cleaving the peptide bonds between neighboring strands in mature murein (By similarity)
E3D14_13365	ENOG4105HA9	of methanol dehydrogenase type
E3D14_13385	ENOG4105ER2	Ompa motb domain protein
E3D14_13390	ENOG4105KWU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
E3D14_13395	ENOG4105ES3	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
E3D14_13400	ENOG4105CQV	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
E3D14_13405	ENOG4105GKE	subunit e
E3D14_13410	ENOG4107QIZ	NADH dehydrogenase
E3D14_13415	ENOG4108IEH	NADH dehydrogenase subunit g
E3D14_13420	ENOG4105CMZ	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone (By similarity)
E3D14_13425	ENOG4105P3U	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
E3D14_13430	ENOG4107UFS	subunit j
E3D14_13435	ENOG41080EA	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
E3D14_13440	ENOG4105D65	subunit l
E3D14_13445	ENOG4105C8S	subunit m
E3D14_13450	ENOG4105CNR	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
E3D14_13465	ENOG4107SDU	Methyl-accepting chemotaxis
E3D14_13470	ENOG4107RAB	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
E3D14_13475	ENOG4107QN8	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
E3D14_13510	ENOG4105K59	histidine triad (HIT) protein
E3D14_13515	ENOG4108NVR	Methyl-accepting chemotaxis
E3D14_13525	ENOG4105CD3	dihydroorotase
E3D14_13540	ENOG4105CK2	sodium dicarboxylate symporter
E3D14_13550	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
E3D14_13555	ENOG4105DU1	integral membrane protein, terc
E3D14_13560	ENOG4108JQ7	(ABC) transporter
E3D14_13570	ENOG4105C3U	ABC transporter
E3D14_13575	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
E3D14_13580	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
E3D14_13585	ENOG4107QSI	ABC, transporter
E3D14_13590	ENOG4105EZI	multiple antibiotic resistance (MarC)-related protein
E3D14_13600	ENOG4108EKI	Dehydrogenase
E3D14_13605	ENOG4105CPI	Metal Dependent Phosphohydrolase
E3D14_13610	ENOG4108HRK	Histidine kinase
E3D14_13615	ENOG4108NEV	two component transcriptional regulator, LytTR family
E3D14_13625	ENOG4105KK7	inner membrane protein YiaW
E3D14_13630	ENOG4105EFX	secretion protein, HlyD family
E3D14_13635	ENOG4105CFI	type iii restriction protein res subunit
E3D14_13640	ENOG4106HRJ	d-alanyl-d-alanine carboxypeptidase
E3D14_13645	ENOG41090BQ	Glutaredoxin
E3D14_13655	ENOG4105CHM	Aminotransferase
E3D14_13660	ENOG4105CSX	c4-dicarboxylate anaerobic carrier
E3D14_13665	ENOG4105RKW	reductase (By
E3D14_13725	ENOG4105C42	Type I secretion membrane fusion protein (HlyD
E3D14_13735	ENOG4105N5T	Radical SAM Protein
E3D14_13740	ENOG4105CBC	glutamate synthase
E3D14_13745	ENOG4105BZ8	glutamate synthase
E3D14_13760	ENOG4108Z4X	TRANSCRIPTIONal
E3D14_13785	ENOG4105C1J	atp-dependent rna helicase
E3D14_13790	ENOG4108MK9	spermidine N(1)-acetyltransferase
E3D14_13825	ENOG4107QS8	(LipO)protein
E3D14_13830	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
E3D14_13835	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
E3D14_13840	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
E3D14_13845	ENOG4105DUK	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity)
E3D14_13860	ENOG4105MK2	5-formyltetrahydrofolate cyclo-ligase
E3D14_13865	ENOG4105E66	phosphoriboisomerase A
E3D14_13870	ENOG4108JQ1	Dehydrogenase
E3D14_13875	ENOG41080IJ	Diacylglycerol kinase
E3D14_13880	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
E3D14_13885	ENOG41080WI	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system (By similarity)
E3D14_13890	ENOG4108ESU	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Involved in the translocation of the substrate across the membrane (By similarity)
E3D14_13895	ENOG4105BZU	Histidine kinase
E3D14_13905	ENOG4105CZX	twitching motility protein
E3D14_13935	ENOG4108ZJT	translation initiation factor, Sui1
E3D14_13995	ENOG4105C8N	cysteinyl-tRNA synthetase
E3D14_14000	ENOG4108R5K	PPIases accelerate the folding of proteins (By similarity)
E3D14_14010	ENOG4105F10	Catalyzes the hydrolysis of the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1- phosphate (lipid X) and UMP (By similarity)
E3D14_14025	ENOG4107EXU	Short-chain dehydrogenase reductase Sdr
E3D14_14030	ENOG4105EQ2	LysR family Transcriptional regulator
E3D14_14040	ENOG4108IYS	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
E3D14_14050	ENOG4105RDA	repressor
E3D14_14115	ENOG4105ED4	portal protein
E3D14_14255	ENOG4105W2W	Cytotoxic translational repressor of toxin-antitoxin stability system
E3D14_14280	ENOG4105CII	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity)
E3D14_14285	ENOG4105WH1	Two component transcriptional regulator luxr family
E3D14_14290	ENOG4105CET	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria (By similarity)
E3D14_14295	ENOG4105W49	UPF0434 protein
E3D14_14300	ENOG4105CHD	Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) (By similarity)
E3D14_14305	ENOG4105BZ1	(ABC) transporter
E3D14_14310	ENOG4108EQH	DNA internalization-related competence protein ComEC Rec2
E3D14_14325	ENOG4105D7A	ATP-binding protein
E3D14_14330	ENOG4105CGF	Aromatic amino acid aminotransferase
E3D14_14340	ENOG4105QMY	Porin Gram-negative type
E3D14_14345	ENOG4105DVT	helicase
E3D14_14355	ENOG4105DGU	Histone deacetylase
E3D14_14360	ENOG4105C9W	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity (By similarity)
E3D14_14365	ENOG4105G6Z	alkaline phosphatase
E3D14_14385	ENOG4105NXH	GreA GreB family elongation factor
E3D14_14390	ENOG4108KX4	response regulator
E3D14_14395	ENOG4105BZU	Histidine kinase
E3D14_14400	ENOG4105CXY	transporter
E3D14_14405	ENOG4105BZU	Histidine kinase
E3D14_14410	ENOG4106PMH	Extracellular solute-binding protein family 3
E3D14_14415	ENOG4105E5Q	amino acid AbC transporter
E3D14_14420	ENOG4105CDA	abc transporter atp-binding protein
E3D14_14430	ENOG4105D5Q	Arginine ornithine antiporter
E3D14_14445	ENOG4105C37	(CBS) domain
E3D14_14455	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
E3D14_14460	ENOG4105E2Z	phosphate ABC transporter (Permease
E3D14_14465	ENOG4105C8U	phosphate abc transporter
E3D14_14470	ENOG4108Z6B	deaminase
E3D14_14480	ENOG4107QP3	malate synthase g
E3D14_14485	ENOG4108I9X	Isocitrate lyase
E3D14_14500	ENOG4105CZ5	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate (By similarity)
E3D14_14505	ENOG4105CXB	phosphoribosylaminoimidazole synthetase
E3D14_14510	ENOG4108V3E	phosphoribosylglycinamide formyltransferase
E3D14_14515	ENOG4107QNR	UPF0135 protein
E3D14_14520	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
E3D14_14525	ENOG4105BZU	Histidine kinase
E3D14_14545	ENOG4105CUU	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) (By similarity)
E3D14_14550	ENOG4105C9X	ppx gppa phosphatase
E3D14_14555	ENOG4105CJW	magnesium transporter
E3D14_14570	ENOG4108ZW7	flagellar rod assembly protein muramidase flgj
E3D14_14575	ENOG4105D92	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity)
E3D14_14580	ENOG4107W7W	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity)
E3D14_14585	ENOG4105CGA	flagellar basal-body rod protein FlgG
E3D14_14590	ENOG4108KPB	Flagellar basal-body rod protein FlgF
E3D14_14595	ENOG4105BZE	flagellar hook protein, FlgE
E3D14_14605	ENOG4108ZC9	flagellar basal-body rod protein flgc
E3D14_14610	ENOG4105K88	Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body (By similarity)
E3D14_14615	ENOG4105BZU	Histidine kinase
E3D14_14620	ENOG4107R88	Chemotaxis protein (CheV)
E3D14_14640	ENOG4108RE9	Phosphodiesterase
E3D14_14645	ENOG4108J59	Extracellular solute-binding protein, family 5
E3D14_14655	ENOG4105I08	Pseudouridine synthase
E3D14_14660	ENOG4105CPI	Metal Dependent Phosphohydrolase
E3D14_14700	ENOG4105VEQ	Cold shock protein
E3D14_14705	ENOG4107QSN	dihydrolipoamide acetyltransferase
E3D14_14715	ENOG4105CPP	Dehydrogenase, E1 component
E3D14_14720	ENOG4107RUY	(E1 component), alpha subunit
E3D14_14740	ENOG4105F5W	AtP-binding protein
E3D14_14745	ENOG4105D70	Integrase catalytic subunit
E3D14_14760	ENOG4108YXG	UPF0502 protein
E3D14_14785	ENOG4105CG5	Glycosyl transferase (Group 1
E3D14_14820	ENOG4105ESV	Glycosyl transferase, family 4
E3D14_14840	ENOG4107QWE	)-transporter
E3D14_14870	ENOG4107EF8	Glycosyl transferase (Group 1
E3D14_14880	ENOG4105EY8	ABC transporter
E3D14_14890	ENOG4105GVR	general secretion pathway protein D
E3D14_14925	ENOG4108VAU	general secretion pathway protein G
E3D14_14930	ENOG4105D7Q	type ii secretion system
E3D14_14935	ENOG4107QHF	type ii secretion system protein e
E3D14_14945	ENOG4108URP	Dtdp-4-dehydrorhamnose 3,5-epimerase
E3D14_14955	ENOG4105DBZ	Dtdp-4-dehydrorhamnose reductase
E3D14_14960	ENOG4105C1B	dTDP-glucose 4-6-dehydratase
E3D14_14970	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
E3D14_14975	ENOG4105BZS	acriflavin resistance protein
E3D14_14980	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
E3D14_14985	ENOG4108IG5	Transcriptional regulator
E3D14_15000	ENOG4105C29	acyl-CoA thioesterase
E3D14_15005	ENOG4105FE9	pseudouridine synthase
E3D14_15010	ENOG4105K8I	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves (By similarity)
E3D14_15020	ENOG4107RTD	sua5 ycio yrdc ywlc family protein
E3D14_15025	ENOG4105DB7	PHP domain protein
E3D14_15030	ENOG4105CRQ	synthase (Component I)
E3D14_15035	ENOG4108EFP	Anthranilate synthase component II
E3D14_15040	ENOG4108I0Q	anthranilate phosphoribosyltransferase
E3D14_15045	ENOG4105DK0	Indole-3-glycerol phosphate synthase
E3D14_15050	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
E3D14_15055	ENOG4105F6H	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate (By similarity)
E3D14_15085	ENOG4105DM4	PTS System
E3D14_15090	ENOG4105CXY	transporter
E3D14_15095	ENOG4108YRF	PTS System
E3D14_15105	ENOG4108R99	pseudouridine synthase
E3D14_15115	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
E3D14_15120	ENOG41075W9	High frequency lysogenization protein HflD homolog
E3D14_15125	ENOG4107QTF	adenylosuccinate lyase
E3D14_15130	ENOG4105EZE	Cupin 4 family protein
E3D14_15150	ENOG4108YYD	acetyltransferase
E3D14_15160	ENOG4108TGY	Glutathione S-transferase
E3D14_15165	ENOG4108S7T	Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) (By similarity)
E3D14_15185	ENOG4105M2J	Glutaredoxin
E3D14_15190	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
E3D14_15195	ENOG410903C	(LipO)protein
E3D14_15205	ENOG4105KWW	Biogenesis protein
E3D14_15210	ENOG4107QX9	Thiol disulfide interChange protein
E3D14_15215	ENOG4105DA4	cytochrome c-type biogenesis protein
E3D14_15220	ENOG4108ZKK	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH (By similarity)
E3D14_15225	ENOG4105X3C	heme exporter protein
E3D14_15230	ENOG41060IM	Heme exporter protein
E3D14_15235	ENOG4105CA5	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes (By similarity)
E3D14_15250	ENOG4108V3W	Chemotaxis protein, CheW
E3D14_15260	ENOG4107QJE	Chromosome Partitioning Protein
E3D14_15265	ENOG4108SEK	ompa motb domain protein
E3D14_15275	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
E3D14_15280	ENOG4105CBS	Chea signal transduction histidine kinase
E3D14_15285	ENOG4108KCC	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P) (By similarity)
E3D14_15290	ENOG4108VYJ	response regulator receiver protein
E3D14_15295	ENOG4105DN4	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
E3D14_15300	ENOG4107R21	site-determining protein
E3D14_15305	ENOG4105FZW	flagellar biosynthesis regulator FlhF
E3D14_15310	ENOG4105D7B	Flagellar biosynthesis protein flha
E3D14_15315	ENOG4105D00	flagellar biosynthetic protein flhB
E3D14_15320	ENOG4105D19	Role in flagellar biosynthesis (By similarity)
E3D14_15325	ENOG4105VS8	Flagellar biosynthetic protein fliq
E3D14_15330	ENOG4105CN7	Flagellar biosynthetic protein FliP
E3D14_15335	ENOG4105VTB	flagellar biosynthesis protein fliO
E3D14_15340	ENOG4105DD5	Flagellar motor switch protein
E3D14_15345	ENOG4105D24	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
E3D14_15365	ENOG4108JIR	Flagellum-specific ATP synthase
E3D14_15375	ENOG4105CS3	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
E3D14_15380	ENOG4105C1F	The M ring may be actively involved in energy transduction (By similarity)
E3D14_15385	ENOG4105VQ0	flagellar hook-basal body complex protein fliE
E3D14_15395	ENOG4105EFZ	amidohydrolase
E3D14_15410	ENOG4105VYW	UPF0251 protein
E3D14_15425	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
E3D14_15430	ENOG4105CBM	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 (By similarity)
E3D14_15440	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
E3D14_15445	ENOG4105CEQ	signal transduction histidine kinase regulating citrate malate metabolism
E3D14_15455	ENOG4106KNT	transcriptional regulator
E3D14_15460	ENOG4105CA9	Pyruvate kinase
E3D14_15470	ENOG4105BZS	acriflavin resistance protein
E3D14_15475	ENOG4107QPN	acyl-Coa dehydrogenase
E3D14_15485	ENOG4107SSZ	Phosphatase
E3D14_15520	ENOG4105CNA	YD repeat protein
E3D14_15530	ENOG4105F5W	AtP-binding protein
E3D14_15535	ENOG4105D70	Integrase catalytic subunit
E3D14_15570	ENOG4107N1Q	ErfK YbiS YcfS YnhG family protein
E3D14_15585	ENOG4105EBA	Specifically methylates the adenine in position 1618 of 23S rRNA (By similarity)
E3D14_15590	ENOG4107TT5	NLP P60 protein
E3D14_15595	ENOG4107YAK	holo-(acyl carrier protein) synthase 2
E3D14_15600	ENOG4107QR8	Thioredoxin
E3D14_15610	ENOG4105C66	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity)
E3D14_15615	ENOG4105CIY	formyltetrahydrofolate deformylase
E3D14_15625	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
E3D14_15650	ENOG4105E4C	Lytic transglycosylase catalytic
E3D14_15655	ENOG4105D8C	Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity)
E3D14_15660	ENOG4105NHU	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group (By similarity)
E3D14_15665	ENOG4105EP9	oxidoreductase
E3D14_15700	ENOG4105CCT	upf0313 protein
E3D14_15710	ENOG4105BZS	acriflavin resistance protein
E3D14_15715	ENOG4105ENT	Efflux transporter rnd family, mfp subunit
E3D14_15720	ENOG4105BZU	Histidine kinase
E3D14_15725	ENOG4105D78	K07001 NTE family protein
E3D14_15730	ENOG4105C8J	)-transporter
E3D14_15745	ENOG4105UYK	outer membrane protein a
E3D14_15750	ENOG4105UYK	outer membrane protein a
E3D14_15755	ENOG4105UYK	outer membrane protein a
E3D14_15760	ENOG4107R1I	NAD-dependent malic enzyme
E3D14_15765	ENOG41075H3	AraC family transcriptional regulator
E3D14_15770	ENOG4105UQX	Mate efflux family protein
E3D14_15775	ENOG4105RKX	Protein of unknown function (DUF2498)
E3D14_15780	ENOG4105BZU	Histidine kinase
E3D14_15785	ENOG4105C2W	permease
E3D14_15790	ENOG4108KMH	lipoate-protein ligase a
E3D14_15795	ENOG4105BZG	amino acid carrier protein
E3D14_15820	ENOG4105PTV	Nudix Hydrolase
E3D14_15840	ENOG4105CJ1	ABC, transporter
E3D14_15845	ENOG4108V1T	peptidylprolyl cis-trans isomerase
E3D14_15850	ENOG4106N3A	copper homeostasis protein cutc
E3D14_15855	ENOG4105EZX	Catalyzes the phosphorylation of N-acetyl-D-glucosamine (GlcNAc) derived from cell-wall degradation, yielding GlcNAc-6-P (By similarity)
E3D14_15865	ENOG4105ERG	peptidase m48, ste24p
E3D14_15875	ENOG4105BZU	Histidine kinase
E3D14_15880	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
E3D14_15885	ENOG4108ZI4	Glyoxalase Bleomycin resistance protein (Dioxygenase
E3D14_15910	ENOG4106YYS	transcriptional regulatory protein
E3D14_15915	ENOG4105CEQ	signal transduction histidine kinase regulating citrate malate metabolism
E3D14_15920	ENOG4107R1I	NAD-dependent malic enzyme
E3D14_15935	ENOG4108US0	Transcription regulator that can specifically activate or repress expression of target genes (By similarity)
E3D14_15940	ENOG4105J12	Multidrug resistance protein mdtN
E3D14_15965	ENOG4108RDD	Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine (By similarity)
E3D14_15975	ENOG4105CJD	(Anaerobic) ribonucleoside-triphosphate reductase
E3D14_15985	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
E3D14_15995	ENOG4105CDB	Required for chromosome condensation and partitioning (By similarity)
E3D14_16000	ENOG4105EXN	Sulfate transport protein CysZ
E3D14_16005	ENOG4105EN6	Membrane
E3D14_16015	ENOG4105EAQ	(twin-arginine translocation) pathway signal
E3D14_16020	ENOG4105DIT	ErfK YbiS YcfS YnhG family protein
E3D14_16050	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
E3D14_16055	ENOG4105DR5	peptidase
E3D14_16060	ENOG4105ED7	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling (By similarity)
E3D14_16065	ENOG4105KME	endoribonuclease L-psp
E3D14_16075	ENOG4105CV1	Transketolase (EC 2.2.1.1)
E3D14_16080	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
E3D14_16085	ENOG4105GPY	SprT protein
E3D14_16095	ENOG4105QF0	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity)
E3D14_16100	ENOG4105D7Z	glutathione synthase
E3D14_16110	ENOG4108UJU	UPF0301 protein
E3D14_16115	ENOG4107Y66	Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity)
E3D14_16120	ENOG4105G2Y	Transcriptional regulator
E3D14_16135	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
E3D14_16145	ENOG4105F8C	transglutaminase domain-containing protein
E3D14_16150	ENOG4105BZG	amino acid carrier protein
E3D14_16155	ENOG4105CW3	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
E3D14_16170	ENOG4105D5S	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine (By similarity)
E3D14_16185	ENOG4108VKA	Acts as a radical domain for damaged PFL and possibly other radical proteins (By similarity)
E3D14_16190	ENOG4105CK2	sodium dicarboxylate symporter
E3D14_16195	ENOG4105CXR	Phospho-2-dehydro-3-deoxyoctonate aldolase
E3D14_16210	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
E3D14_16215	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
E3D14_16220	ENOG4105C7E	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) (By similarity)
E3D14_16225	ENOG4105C1U	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein (By similarity)
E3D14_16230	ENOG4105CTR	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol (By similarity)
E3D14_16240	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
E3D14_16245	ENOG4105CGH	5'-nucleotidase
E3D14_16250	ENOG4108ZPD	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity)
E3D14_16255	ENOG4105C3G	gtp-binding protein
E3D14_16325	ENOG4107QWE	)-transporter
E3D14_16330	ENOG4106Z1T	Nicotinamide Mononucleotide Transporter
E3D14_16335	ENOG4108I5U	Uridine phosphorylase
E3D14_16345	ENOG41060QA	UPF0267 protein
E3D14_16365	ENOG4105F7F	Chaperone
E3D14_16375	ENOG4105CG3	alpha amylase, catalytic region
E3D14_16390	ENOG4105C5H	ABC transporter
E3D14_16395	ENOG4107QF7	multi-drug
E3D14_16400	ENOG4105D95	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin (By similarity)
E3D14_16410	ENOG4107VXZ	Hydrolase
E3D14_16420	ENOG4105C26	Dehydrogenase
E3D14_16430	ENOG4105C8Y	Acetylornithine aminotransferase
E3D14_16435	ENOG4105DDQ	anthranilate synthase
E3D14_16445	ENOG4105C31	Tryptophanyl-tRNA synthetase
E3D14_16450	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
E3D14_16455	ENOG4105DJV	ribulose-phosphate 3-epimerase
E3D14_16460	ENOG4105DFE	Dna adenine methylase
E3D14_16470	ENOG4105D49	3-dehydroquinate synthase
E3D14_16475	ENOG4105KHV	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
E3D14_16480	ENOG4105E4G	Type IV pilus
E3D14_16505	ENOG4108JQC	penicillin-binding protein 1A
E3D14_16510	ENOG4105C5Q	Transcriptional regulator
E3D14_16530	ENOG4105EJC	lysr family transcriptional regulator
E3D14_16545	ENOG4105DR5	peptidase
E3D14_16565	ENOG4105EGS	Mechanosensitive ion channel
E3D14_16570	ENOG4108QXE	glycerophosphoryl diester phosphodiesterase
E3D14_16575	ENOG4105C8Q	Methyl-accepting chemotaxis
E3D14_16585	ENOG4105E33	succinate dehydrogenase
E3D14_16590	ENOG4108WJH	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane (By similarity)
E3D14_16595	ENOG4108VP9	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane (By similarity)
E3D14_16615	ENOG4105T0Z	Conserved Protein
E3D14_16650	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
E3D14_16655	ENOG4105DHQ	Histidine kinase
E3D14_16665	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
E3D14_16675	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
E3D14_16685	ENOG4105C5I	Dehydrogenase
E3D14_16705	ENOG4105EVE	HAD-superfamily hydrolase subfamily IA variant 3
E3D14_16720	ENOG4105BZU	Histidine kinase
E3D14_16725	ENOG4105VEQ	Cold shock protein
E3D14_16730	ENOG4105EAK	ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family
E3D14_16735	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
E3D14_16740	ENOG4105C9A	Phoh family
E3D14_16745	ENOG4105KGE	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA (By similarity)
E3D14_16750	ENOG4108JU5	Magnesium and cobalt efflux protein
E3D14_16755	ENOG4105CE8	Transfers the fatty acyl group on membrane lipoproteins (By similarity)
E3D14_16760	ENOG4107PAI	alpha helical protein
E3D14_16765	ENOG4105C8T	Leucyl-tRNA synthetase
E3D14_16785	ENOG4108Z1W	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity)
E3D14_16790	ENOG4105KEM	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation (By similarity)
E3D14_16795	ENOG4108UXA	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA (By similarity)
E3D14_16800	ENOG4105CJN	penicillin-binding protein
E3D14_16805	ENOG4105CNI	cell division protein FtsW
E3D14_16815	ENOG4105K6T	rare lipoprotein A
E3D14_16820	ENOG4105DZ1	carboxypeptidase
E3D14_16825	ENOG4108Z43	UPF0250 protein
E3D14_16830	ENOG4108BDP	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity)
E3D14_16835	ENOG4105C0G	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity)
E3D14_16850	ENOG4108ZXE	
E3D14_16870	ENOG4105F5W	AtP-binding protein
E3D14_16875	ENOG4105D70	Integrase catalytic subunit
E3D14_16920	ENOG4108HK0	-acetyltransferase
E3D14_16925	ENOG4105MJ9	esterase
E3D14_16930	ENOG4108IUB	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
E3D14_16940	ENOG4105C2R	Single-stranded-DNA-specific exonuclease (RecJ)
E3D14_16950	ENOG4105M2E	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell (By similarity)
E3D14_16955	ENOG4105BZU	Histidine kinase
E3D14_16960	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
E3D14_16965	ENOG41071R3	Low-potential electron donor to a number of redox enzymes (By similarity)
E3D14_16970	ENOG4105D1U	peptidase U62 modulator of DNA gyrase
E3D14_16985	ENOG4107N1Q	ErfK YbiS YcfS YnhG family protein
E3D14_17020	ENOG4105EQ6	Hydrolyzes dipeptides containing N-terminal aspartate residues. May play a role in allowing the cell to use peptide aspartate to spare carbon otherwise required for the synthesis of the aspartate family of amino acids (By similarity)
E3D14_17030	ENOG4105WAY	exported protein
E3D14_17035	ENOG41090EX	DsrE family
E3D14_17040	ENOG4105BZU	Histidine kinase
E3D14_17050	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
E3D14_17055	ENOG4105K77	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity)
E3D14_17060	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
E3D14_17065	ENOG4105KG7	Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity)
E3D14_17070	ENOG4107QHU	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
E3D14_17075	ENOG4105CHV	Transcription elongation factor NusA
E3D14_17080	ENOG4105K7D	Required for maturation of 30S ribosomal subunits (By similarity)
E3D14_17100	ENOG4105CP7	Triose-phosphate isomerase
E3D14_17105	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
E3D14_17110	ENOG4105EEI	dihydropteroate synthase
E3D14_17115	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
E3D14_17120	ENOG4105F7M	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit (By similarity)
E3D14_17125	ENOG4105HBR	Rna-binding protein
E3D14_17135	ENOG4108UKH	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
E3D14_17150	ENOG4105E14	MotA TolQ exbB proton channel
E3D14_17155	ENOG41067QG	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
E3D14_17160	ENOG4105CTB	Polyprenyl synthetase
E3D14_17165	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
E3D14_17175	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
E3D14_17185	ENOG4108JQ6	ABC transporter
E3D14_17190	ENOG4108ZAI	phosphatidylglycerophosphatase a
E3D14_17195	ENOG4105CG2	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity)
E3D14_17200	ENOG4107YIM	Involved in the transcription termination process (By similarity)
E3D14_17205	ENOG4108UTT	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity)
E3D14_17220	ENOG4105D1W	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity)
E3D14_17225	ENOG4108Z11	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes (By similarity)
E3D14_17240	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
E3D14_17260	ENOG4109039	Involved in the biogenesis of TorA. Acts on TorA before the insertion of the molybdenum cofactor and, as a result, probably favors a conformation of the apoenzyme that is competent for acquiring the cofactor (By similarity)
E3D14_17280	ENOG4105BZU	Histidine kinase
E3D14_17290	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
E3D14_17295	ENOG4108Z38	Catalyzes a trans-dehydration via an enolate intermediate (By similarity)
E3D14_17300	ENOG4105KM4	Acetyl-CoA carboxylase, biotin carboxyl carrier protein
E3D14_17305	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
E3D14_17310	ENOG4105RG0	Membrane
E3D14_17315	ENOG4108IA2	Sodium pantothenate symporter
E3D14_17320	ENOG4105CI1	PTS System
E3D14_17325	ENOG4105HEI	LysR family (Transcriptional regulator
E3D14_17330	ENOG4105CIS	alcohol dehydrogenase
E3D14_17335	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
E3D14_17345	ENOG4105CPD	ethanolamine ammonia-lyase
E3D14_17350	ENOG4107FQ9	ethanolamine ammonia-lyase
E3D14_17370	ENOG41069NU	Nitroreductase
E3D14_17375	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
E3D14_17380	ENOG4105D07	Signal peptide peptidase, SppA
E3D14_17400	ENOG4105VUT	cytoplasmic protein
E3D14_17405	ENOG4105HDK	L-asparaginase
E3D14_17410	ENOG4105D6U	Sodium Glutamate Symporter
E3D14_17415	ENOG4105C8Q	Methyl-accepting chemotaxis
E3D14_17425	ENOG4105CRK	lysyL-tRNA synthetase
E3D14_17430	ENOG4107TIF	Phenazine biosynthesis protein, PhzF family
E3D14_17445	ENOG4105ET3	Reduction of activated sulfate into sulfite (By similarity)
E3D14_17450	ENOG4105GIJ	Glycine betaine
E3D14_17455	ENOG4108HQS	Glycine betaine
E3D14_17460	ENOG4108IJ7	Glycine betaine
E3D14_17470	ENOG4107XM3	UPF0442 protein
E3D14_17475	ENOG4105DWK	Membrane
E3D14_17485	ENOG4108RIR	Molybdenum cofactor biosynthesis protein
E3D14_17495	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
E3D14_17500	ENOG4105C2D	reductase
E3D14_17510	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
E3D14_17535	ENOG4105C84	Histidine ammonia-lyase
E3D14_17550	ENOG4108KW7	amp-dependent synthetase and ligase
E3D14_17565	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
E3D14_17600	ENOG4105CA0	peroxidase
E3D14_17610	ENOG4105D53	Catalyzes the hydrolysis of pseudouridine 5'-phosphate (PsiMP) to ribose 5-phosphate and uracil (By similarity)
E3D14_17615	ENOG4105DD7	kinase (PfkB family
E3D14_17645	ENOG4105C2S	Catalyzes the NADPH dependent reduction of L-gamma- glutamyl 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate (By similarity)
E3D14_17650	ENOG4105CGT	Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity)
E3D14_17660	ENOG4105V1F	Fermentation respiration switch protein
E3D14_17665	ENOG4105DYA	Acts on guanine, xanthine and to a lesser extent hypoxanthine (By similarity)
E3D14_17680	ENOG4105CIN	aminoacyl-histidine dipeptidase
E3D14_17690	ENOG4108JQ7	(ABC) transporter
E3D14_17700	ENOG4107QRA	Extracellular solute-binding protein, family 5
E3D14_17705	ENOG4108IYQ	Binding-protein-dependent transport systems inner membrane component
E3D14_17735	ENOG4109015	Biopolymer transport protein exbD tolR
E3D14_17780	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
E3D14_17785	ENOG4105C8Q	Methyl-accepting chemotaxis
E3D14_17795	ENOG4105VEQ	Cold shock protein
E3D14_17825	ENOG4108RBP	3'-to-5' exoribonuclease specific for small oligoribonucleotides (By similarity)
E3D14_17835	ENOG4105DJ4	phosphatidylserine decarboxylase
E3D14_17840	ENOG4105VYA	Uncharacterized conserved protein (DUF2132)
E3D14_17860	ENOG4105BZU	Histidine kinase
E3D14_17865	ENOG4105KQT	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome (By similarity)
E3D14_17870	ENOG4107G87	m6 family metalloprotease domain protein
E3D14_17900	ENOG4105C26	Dehydrogenase
E3D14_17915	ENOG4105BZ1	(ABC) transporter
E3D14_17920	ENOG4105SUV	lipoprotein YgdR
E3D14_17925	ENOG4107RM6	sulfurtransferase
E3D14_17930	ENOG4105CSV	Glutaminase
E3D14_17935	ENOG41090ED	Protein with unknown function (DUF469)
E3D14_17940	ENOG4105CZ1	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity)
E3D14_17955	ENOG4105BZU	Histidine kinase
E3D14_17960	ENOG4105ECP	epimerase
E3D14_17965	ENOG4105CV6	ABC transporter, permease
E3D14_17970	ENOG4108I0Y	(ABC) transporter
E3D14_17975	ENOG4108UJV	acyl-CoA thioesterase i
E3D14_17980	ENOG4107R88	Chemotaxis protein (CheV)
E3D14_17990	ENOG4105D0C	transport protein
E3D14_17995	ENOG4108UT2	hemolysin iii
E3D14_18000	ENOG4105DY8	decarboxylase
E3D14_18005	ENOG4107835	probably involved in intracellular septation (By similarity)
E3D14_18010	ENOG4105K9H	YciI-like protein
E3D14_18015	ENOG4108RNI	3'(2')5'-bisphosphate nucleotidase
E3D14_18020	ENOG41083P1	competence protein ComEA helix-hairpin-helix repeat protein
E3D14_18025	ENOG4105C3Y	UTP-glucose-1-phosphate uridylyltransferase
E3D14_18030	ENOG4105DUX	Transporter
E3D14_18035	ENOG4105I93	response regulator
E3D14_18065	ENOG4107V40	secretion protein, HlyD family
E3D14_18075	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
E3D14_18080	ENOG4105VY0	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters (By similarity)
E3D14_18085	ENOG410829K	Lysine exporter protein (Lyse ygga)
E3D14_18115	ENOG4108YX9	iron--sulfur cluster insertion protein erpA
E3D14_18125	ENOG4105CMQ	Chloride channel
E3D14_18130	ENOG4105CDM	Glutamate-1-semialdehyde aminotransferase
E3D14_18145	ENOG41076MN	Phosphoesterase, PA-phosphatase related
E3D14_18155	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
E3D14_18160	ENOG4105CWB	LysR family transcriptional Regulator
E3D14_18165	ENOG41090TI	Catalyzes the excretion of spermidine (By similarity)
E3D14_18170	ENOG4108ZBZ	Catalyzes the excretion of spermidine (By similarity)
E3D14_18175	ENOG4108YZK	glyoxalase bleomycin resistance protein dioxygenase
E3D14_18180	ENOG4105BZ4	penicillin-binding protein
E3D14_18185	ENOG4105CQ7	ATP-dependent helicase
E3D14_18195	ENOG4105PW4	Sugar fermentation stimulation protein homolog
E3D14_18200	ENOG4108V7X	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
E3D14_18205	ENOG4106F3G	Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon (By similarity)
E3D14_18210	ENOG4105DJ0	Poly(A) Polymerase
E3D14_18215	ENOG4105K8U	2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
E3D14_18220	ENOG4105CCG	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is tranferred onto alpha-ketoisovalerate to form ketopantoate (By similarity)
E3D14_18225	ENOG4108IAA	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate (By similarity)
E3D14_18235	ENOG4105E3A	(ABC) transporter
E3D14_18240	ENOG4105DA5	(ABC) transporter
E3D14_18245	ENOG4108UGV	hypoxanthine phosphoribosyltransferase
E3D14_18250	ENOG410630P	Transcriptional regulator
E3D14_18255	ENOG4108UMA	3-octaprenyl-4-hydroxybenzoate carboxy-lyase
E3D14_18260	ENOG4105DFU	Cell wall formation (By similarity)
E3D14_18265	ENOG4105F0N	pyrophosphate phospho-hydrolase
E3D14_18270	ENOG4105CFZ	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III (By similarity)
E3D14_18275	ENOG4105E09	nadh pyrophosphatase
E3D14_18280	ENOG4105C26	Dehydrogenase
E3D14_18285	ENOG4106MWK	domain protein
E3D14_18290	ENOG4105EYW	Ion transport protein
E3D14_18300	ENOG4105E0X	reductase
E3D14_18310	ENOG4105C9C	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity)
E3D14_18315	ENOG4107RTM	4-alpha-glucanotransferase (EC 2.4.1.25)
E3D14_18320	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
E3D14_18325	ENOG4105DSB	aldose 1-epimerase
E3D14_18330	ENOG4105D0I	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate (By similarity)
E3D14_18400	ENOG4105UFD	tol-pal system protein YbgF
E3D14_18405	ENOG4105KCK	Peptidoglycan-associated lipoprotein
E3D14_18410	ENOG4107R6Y	Involved in the TonB-independent uptake of proteins (By similarity)
E3D14_18420	ENOG4105M8F	Biopolymer transport protein exbD tolR
E3D14_18425	ENOG4105E02	MotA TolQ exbB proton channel
E3D14_18430	ENOG4107YD3	Thioesterase
E3D14_18435	ENOG4105KJB	cyd operon protein YbgE
E3D14_18445	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
E3D14_18450	ENOG4105C4M	(Ubiquinol oxidase) subunit I
E3D14_18455	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
E3D14_18460	ENOG4105KA4	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity)
E3D14_18465	ENOG4105C8Q	Methyl-accepting chemotaxis
E3D14_18470	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
E3D14_18480	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
E3D14_18490	ENOG4105C8A	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP (By similarity)
E3D14_18495	ENOG4105BZU	Histidine kinase
E3D14_18505	ENOG4105EW9	transcriptional regulator AsnC family
E3D14_18515	ENOG4105EV2	VWA domain protein interacting with AAA ATPase
E3D14_18520	ENOG4107R4Q	Functions as an ATPase. May play a role in metal insertion (metal-chelatase) or as a chaperone (By similarity)
E3D14_18530	ENOG4108RTV	Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol (By similarity)
E3D14_18540	ENOG4108IQE	Amp-dependent synthetase and ligase
E3D14_18550	ENOG4105D9M	gamma-glutamylcysteine synthetase
E3D14_18560	ENOG4105W39	Membrane
E3D14_18565	ENOG4105DQ4	alcohol dehydrogenase
E3D14_18590	ENOG4105DP0	ferredoxin-NADP reductase
E3D14_18595	ENOG4105K9Q	Binds to the 23S rRNA (By similarity)
E3D14_18600	ENOG4105VH8	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity)
E3D14_18605	ENOG4108ZDX	Binds together with S18 to 16S ribosomal RNA (By similarity)
E3D14_18610	ENOG4105C56	H( )-stimulated, divalent metal cation uptake system (By similarity)
E3D14_18640	ENOG4105C2N	RNA methyltransferase TrmH family group 3
E3D14_18645	ENOG4105C40	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity)
E3D14_18650	ENOG4106TD9	Diguanylate cyclase
E3D14_18655	ENOG4106762	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD) (By similarity)
E3D14_18665	ENOG4108YZA	Nitrogen regulatory protein pii
E3D14_18670	ENOG4105C4K	Nad synthetase
E3D14_18705	ENOG4106855	Competence protein
E3D14_18710	ENOG4105C48	Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) (By similarity)
E3D14_18715	ENOG41090X3	Peptidyl-prolyl cis-trans isomerase
E3D14_18720	ENOG4105M02	This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity)
E3D14_18725	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
E3D14_18730	ENOG4105DTN	riboflavin biosynthesis protein ribF
E3D14_18735	ENOG4105CJR	Integral membrane protein (MviN
E3D14_18740	ENOG4105KQV	Binds directly to 16S ribosomal RNA (By similarity)
E3D14_18745	ENOG41080HT	Transcriptional regulator, arsr family
E3D14_18750	ENOG41063Z6	transcriptional regulator, lysR family
E3D14_18760	ENOG4105DRC	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity)
E3D14_18765	ENOG4105C0V	Provides the sole de novo source of dTMP for DNA biosynthesis (By similarity)
E3D14_18770	ENOG4105C3B	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity)
E3D14_18775	ENOG4108HRM	phosphoenolpyruvate--protein phosphotransferase
E3D14_18780	ENOG4105EJF	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity)
E3D14_18785	ENOG4105IRT	Sequence-specific endonuclease that cleaves unmethylated GATC sequences. It is involved in DNA mismatch repair (By similarity)
E3D14_18795	ENOG4108YY1	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity)
E3D14_18800	ENOG4105D6X	Specifically methylates guanosine-37 in various tRNAs (By similarity)
E3D14_18805	ENOG4108ZR6	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity)
E3D14_18810	ENOG4105K5M	30s ribosomal protein S16
E3D14_18815	ENOG4105CB9	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
E3D14_18820	ENOG4106KVJ	cytochrome C assembly protein
E3D14_18825	ENOG4108JU6	CBS domain protein
E3D14_18830	ENOG4105KPV	Transcriptional regulator
E3D14_18835	ENOG4108EGH	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity)
E3D14_18840	ENOG4108UV7	flagellar protein motX
E3D14_18845	ENOG4105C80	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
E3D14_18850	ENOG4105DMR	ABC, transporter
E3D14_18855	ENOG4105GBT	ABC transporter
E3D14_18860	ENOG4106PMH	Extracellular solute-binding protein family 3
E3D14_18865	ENOG4105E5Z	arginine transporter ATP-binding subunit
E3D14_18870	ENOG410682Y	Regulates arginine biosynthesis genes (By similarity)
E3D14_18875	ENOG4105EZR	dyp-type peroxidase family protein
E3D14_18880	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
E3D14_18895	ENOG4108YZA	Nitrogen regulatory protein pii
E3D14_18900	ENOG4108YZN	class I peptide chain release factor
E3D14_18910	ENOG4105D9N	nucleoside
E3D14_18915	ENOG4105JQN	Transcriptional regulator
E3D14_18930	ENOG4105BZW	Glycerate kinase
E3D14_18935	ENOG4107QQ0	gntp family
E3D14_18935	ENOG4107QQ0	gntp family
E3D14_18940	ENOG4108IXP	Carbohydrate diacid transcriptional activator CdaR
E3D14_18945	ENOG4105XTV	UPF0231 protein
E3D14_18960	ENOG4107RHT	methyl-accepting chemotaxis sensory transducer with Pas Pac sensor
E3D14_18980	ENOG4105C1J	atp-dependent rna helicase
E3D14_18990	ENOG4108V1J	Has antioxidant activity. Could remove peroxides or H(2)O(2) (By similarity)
E3D14_19020	ENOG4105CGF	Aromatic amino acid aminotransferase
E3D14_19035	ENOG41076CZ	activating enzyme
E3D14_19040	ENOG4105G0K	glycine radical enzyme YjjI family
E3D14_19075	ENOG4105CND	Glycosyl transferase, family 2
E3D14_19115	ENOG4105C8Q	Methyl-accepting chemotaxis
E3D14_19120	ENOG4108M1A	Chitin-binding protein
E3D14_19125	ENOG4105CT1	(ABC) transporter
E3D14_19130	ENOG4105CDA	abc transporter atp-binding protein
E3D14_19140	ENOG4105E5Q	amino acid AbC transporter
E3D14_19145	ENOG4108IYI	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine (By similarity)
E3D14_19150	ENOG4107R11	Transcriptional regulator
E3D14_19155	ENOG4108IJ6	ABC transporter
E3D14_19160	ENOG4105ECW	sulfate abc transporter
E3D14_19165	ENOG4108I5D	sulfate abc transporter
E3D14_19175	ENOG4105DE7	Sulfate ABC transporter periplasmic sulfate-binding protein
E3D14_19180	ENOG4107PU6	Membrane
E3D14_19185	ENOG4108UW5	maltose o-acetyltransferase
E3D14_19215	ENOG41090U3	tautomerase
E3D14_19225	ENOG4107NQ8	LysR family Transcriptional regulator
E3D14_19230	ENOG4105CH7	arginosuccinase
E3D14_19235	ENOG4105CDH	Citrulline--aspartate ligase
E3D14_19245	ENOG4105CAS	nag kinase
E3D14_19250	ENOG4105C0N	N-acetylglutamate semialdehyde dehydrogenase
E3D14_19260	ENOG4105CCA	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle (By similarity)
E3D14_19270	ENOG4105H3G	oxidoreductase
E3D14_19280	ENOG4105K89	arsenate reductase
E3D14_19285	ENOG4105D6J	arsenicaL-resistance protein
E3D14_19305	ENOG4105D86	that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity)
E3D14_19325	ENOG4105R2J	Conserved Protein
E3D14_19335	ENOG4105DR5	peptidase
E3D14_19355	ENOG4105NXV	High-affinity zinc uptake system protein
E3D14_19360	ENOG4105FDK	ABC transporter
E3D14_19365	ENOG4105FAV	ABC, transporter
E3D14_19370	ENOG4105ETT	transcriptional Regulator, LysR family
E3D14_19380	ENOG4108RG0	uracil-dna glycosylase
E3D14_19385	ENOG4105FR1	rard protein
E3D14_19395	ENOG41082IR	Excinuclease ABC C subunit domain protein
E3D14_19410	ENOG41087YS	Phage shock protein A
E3D14_19415	ENOG4107S7E	1-acyl-sn-glycerol-3-phosphate acyltransferase
E3D14_19445	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
E3D14_19480	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
E3D14_19485	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
E3D14_19500	ENOG4105IPS	esterase
E3D14_19505	ENOG41070EG	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes (By similarity)
E3D14_19510	ENOG4108SX3	cytoplasmic protein
E3D14_19520	ENOG41087AY	ADP-Ribose pyrophosphatase
E3D14_19530	ENOG4105DFG	type I secretion outer membrane protein
E3D14_19535	ENOG4105DW0	Catalyzes the ADP transfer to D-glycero-D-manno-heptose 1-phosphate, yielding ADP-D,D-heptose (By similarity)
E3D14_19540	ENOG4105D1S	lipid A biosynthesis
E3D14_19555	ENOG4107IX6	phosphate transport regulator
E3D14_19560	ENOG4105CJ3	phosphate transporter
E3D14_19565	ENOG4105D4J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
E3D14_19580	ENOG4105CEN	a g-specific adenine glycosylase
E3D14_19585	ENOG4105KMG	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes (By similarity)
E3D14_19595	ENOG4105H4F	exported protein
E3D14_19610	ENOG4105UYK	outer membrane protein a
E3D14_19615	ENOG4108Q2G	(LipO)protein
E3D14_19620	ENOG4105DY2	Paraquat-inducible protein b
E3D14_19625	ENOG4105F1S	paraquat-inducible protein a
E3D14_19630	ENOG4105KW8	RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity)
E3D14_19635	ENOG4107VXZ	Hydrolase
E3D14_19650	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
E3D14_19655	ENOG4105D8J	Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle (By similarity)
E3D14_19660	ENOG4107QQ4	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans (By similarity)
E3D14_19665	ENOG4105CXW	Synthesizes alpha-1,4-glucan chains using ADP-glucose (By similarity)
E3D14_19705	ENOG4105DFD	Na H antiporter
E3D14_19715	ENOG4108UW5	maltose o-acetyltransferase
E3D14_19720	ENOG4105CG3	alpha amylase, catalytic region
E3D14_19730	ENOG4105D4X	repressor
E3D14_19740	ENOG4105CK1	PTS System
E3D14_19745	ENOG4105VZJ	PTS System
E3D14_19750	ENOG4105CK1	PTS System
E3D14_19755	ENOG4105CS2	ec 3.2.1.21
E3D14_19760	ENOG4105VCP	PTS System
E3D14_19765	ENOG4105DKQ	ROK family
E3D14_19775	ENOG4105DDV	Transcriptional regulator (LacI family
E3D14_19785	ENOG4105HDK	L-asparaginase
E3D14_19800	ENOG4108Z5K	methylglyoxal synthase
E3D14_19810	ENOG4108UQY	Iron-storage protein
E3D14_19825	ENOG4105E0I	Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of tRNA(Met), by using acetyl-CoA as an acetyl donor and ATP (or GTP) (By similarity)
E3D14_19830	ENOG410904N	short-chain dehydrogenase reductase
E3D14_19835	ENOG4107R88	Chemotaxis protein (CheV)
E3D14_19845	ENOG4105DWD	nucleoside recognition domain protein
E3D14_19955	ENOG4105K7Z	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP (By similarity)
E3D14_19960	ENOG4107ZVW	dihydroneopterin aldolase
E3D14_19965	ENOG4105K8U	2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
E3D14_19975	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
E3D14_19980	ENOG4105CKI	cobalamin synthesis protein
E3D14_19990	ENOG4105E82	cytochrome subunit of dehydrogenase
E3D14_19995	ENOG4108MGI	Transcriptional regulator
E3D14_20000	ENOG4105HEI	LysR family (Transcriptional regulator
E3D14_20005	ENOG4105F6U	Short-chain dehydrogenase reductase Sdr
E3D14_20010	ENOG4105BZU	Histidine kinase
E3D14_20015	ENOG4107QIJ	Aconitate hydratase 2
E3D14_20030	ENOG4108N3W	hemolysin secretion protein
E3D14_20040	ENOG4105BZU	Histidine kinase
E3D14_20045	ENOG4107QN2	dihydrolipoyl dehydrogenase
E3D14_20050	ENOG4107QSN	dihydrolipoamide acetyltransferase
E3D14_20055	ENOG4105DAQ	Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) (By similarity)
E3D14_20060	ENOG41073TP	transcriptional regulator
E3D14_20075	ENOG4105D18	nicotinate-nucleotide pyrophosphorylase
E3D14_20085	ENOG4107QHF	type ii secretion system protein e
E3D14_20095	ENOG4105EHH	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue (By similarity)
E3D14_20105	ENOG4105DHA	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity (By similarity)
E3D14_20110	ENOG41067SF	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase (By similarity)
E3D14_20115	ENOG4105M6F	mutator MutT protein
E3D14_20125	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
E3D14_20135	ENOG4105C7C	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
E3D14_20140	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
E3D14_20145	ENOG4105CIT	This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity)
E3D14_20150	ENOG4105K7E	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly (By similarity)
E3D14_20155	ENOG4105DFU	Cell wall formation (By similarity)
E3D14_20160	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
E3D14_20165	ENOG4105CNI	cell division protein FtsW
E3D14_20170	ENOG4105DMZ	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity)
E3D14_20175	ENOG4105CPY	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity)
E3D14_20180	ENOG4108EQQ	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein (By similarity)
E3D14_20185	ENOG4107EEN	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity)
E3D14_20190	ENOG4105CJN	penicillin-binding protein
E3D14_20195	ENOG41063Y6	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity)
E3D14_20200	ENOG4105CGJ	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity)
E3D14_20205	ENOG4108V6E	Cell division protein mraZ
E3D14_20215	ENOG4105E9H	Lytic Murein transglycosylase
E3D14_20225	ENOG4105ER2	Ompa motb domain protein
E3D14_20230	ENOG4107RD7	Flagellar Motor Protein, MotA
E3D14_20255	ENOG4105MQ3	flagellar protein FliS
E3D14_20260	ENOG410804A	Flagellar hook-associated 2 domain-containing protein
E3D14_20275	ENOG4105I03	Flagellin
E3D14_20295	ENOG4105E1Q	flagellar hook-associated protein
E3D14_20305	ENOG4105D92	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity)
E3D14_20310	ENOG4107W7W	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity)
E3D14_20315	ENOG4105CGA	flagellar basal-body rod protein FlgG
E3D14_20320	ENOG4108JQA	flagellar
E3D14_20325	ENOG4105BZE	flagellar hook protein, FlgE
E3D14_20335	ENOG4108ZC9	flagellar basal-body rod protein flgc
E3D14_20340	ENOG4105K88	Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body (By similarity)
E3D14_20350	ENOG4105M9M	anti-sigma28 factor FlgM
E3D14_20365	ENOG4108JIR	Flagellum-specific ATP synthase
E3D14_20375	ENOG4105CS3	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
E3D14_20380	ENOG4105C1F	The M ring may be actively involved in energy transduction (By similarity)
E3D14_20385	ENOG4105VQ0	flagellar hook-basal body complex protein fliE
E3D14_20390	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
E3D14_20400	ENOG4105D00	flagellar biosynthetic protein flhB
E3D14_20405	ENOG4105D19	Role in flagellar biosynthesis (By similarity)
E3D14_20410	ENOG4105VS8	Flagellar biosynthetic protein fliq
E3D14_20415	ENOG4105CN7	Flagellar biosynthetic protein FliP
E3D14_20420	ENOG4105DD5	Flagellar motor switch protein
E3D14_20435	ENOG4105CU0	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity)
E3D14_20440	ENOG4105E1C	Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1A (PBP1a) (By similarity)
E3D14_20450	ENOG4105F55	Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate (By similarity)
E3D14_20455	ENOG4105W4M	Transport-associated protein
E3D14_20460	ENOG4105KB2	stringent starvation protein b
E3D14_20465	ENOG4107MKT	Stringent starvation protein a
E3D14_20470	ENOG4105EIX	cytochrome c1
E3D14_20475	ENOG4105DJ5	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
E3D14_20480	ENOG4108R5F	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
E3D14_20485	ENOG4108UJD	30S ribosomal protein S9
E3D14_20490	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
E3D14_20495	ENOG4105D6Z	AFG1 family ATPase
E3D14_20505	ENOG4105C0H	protease
E3D14_20510	ENOG4105C0H	protease
E3D14_20545	ENOG41069H0	dihydroorotase EC 3.5.2.3
E3D14_20565	ENOG41080Z8	PHOSPHOCARRIER protein
E3D14_20570	ENOG4105C21	Displays ATPase and GTPase activities (By similarity)
E3D14_20575	ENOG4107RM2	PTS IIA-like nitrogen-regulatory protein PtsN
E3D14_20580	ENOG41080QH	sigma 54 modulation protein ribosomal protein S30EA
E3D14_20585	ENOG4105DTW	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
E3D14_20590	ENOG4108IUZ	ABC transporter
E3D14_20595	ENOG4105WI0	lipopolysaccharide transport periplasmic protein lptA
E3D14_20600	ENOG4108P1K	Required for the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane (By similarity)
E3D14_20605	ENOG4108Z4R	3-deoxy-d-manno-octulosonate 8-phosphate phosphatase
E3D14_20610	ENOG4105C2X	Arabinose 5-phosphate isomerase
E3D14_20615	ENOG4105DHJ	ABC, transporter
E3D14_20620	ENOG4105CY3	ABC transporter, permease
E3D14_20625	ENOG4107PE3	Mammalian cell entry related domain protein
E3D14_20630	ENOG4105E3I	toluene tolerance
E3D14_20640	ENOG4105VFK	BolA family
E3D14_20645	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
E3D14_20650	ENOG4105CMS	peptidase U62, modulator of DNA gyrase
E3D14_20655	ENOG4105N42	UPF0307 protein
E3D14_20665	ENOG41090HJ	UPF0265 protein
E3D14_20690	ENOG4108ZI0	d,d-heptose 1,7-bisphosphate phosphatase
E3D14_20695	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
E3D14_20700	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
E3D14_20705	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
E3D14_20710	ENOG4108UKE	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity)
E3D14_20715	ENOG4105YKK	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions (By similarity)
E3D14_20720	ENOG4108ZKU	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions (By similarity)
E3D14_20730	ENOG4105KME	endoribonuclease L-psp
E3D14_20735	ENOG4105WWK	YheO domain protein
E3D14_20740	ENOG4105D27	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
E3D14_20745	ENOG4108IIJ	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
E3D14_20750	ENOG4105KBC	Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity)
E3D14_20755	ENOG4108VZM	50s ribosomal protein L10
E3D14_20760	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
E3D14_20765	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
E3D14_20770	ENOG4105E5V	Participates in transcription elongation, termination and antitermination (By similarity)
E3D14_20775	ENOG4105PM1	preprotein translocase subunit SecE
E3D14_20785	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
E3D14_20805	ENOG4105HJX	Biotin- acetyl-CoA-carboxylase ligase
E3D14_20810	ENOG4105D4A	Cell wall formation (By similarity)
E3D14_20815	ENOG4107ZYR	domain protein
E3D14_20825	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
E3D14_20830	ENOG4105CUW	cytochrome C-TYPE protein
E3D14_20835	ENOG4107QY8	reductase
E3D14_20845	ENOG4105IFJ	Histidine kinase
E3D14_20850	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
E3D14_20865	ENOG4105DQ2	Is probably involved in the electron transfer between its heme and the molybdenum cofactor of the reductase catalytic subunit YedY (By similarity)
E3D14_20870	ENOG4105CCD	The exact function is not known. Can catalyze the reduction of a variety of substrates like dimethyl sulfoxide, trimethylamine N-oxide, phenylmethyl sulfoxide and L-methionine sulfoxide. Cannot reduce cyclic N-oxides. Shows no activity as sulfite oxidase (By similarity)
E3D14_20880	ENOG4108UQ5	membrane protein YcdZ
E3D14_20885	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
E3D14_20895	ENOG4107WP9	Histidine kinase
E3D14_20910	ENOG410642E	Short chain dehydrogenase
E3D14_20915	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
E3D14_20930	ENOG4108VVK	transcriptional Regulator, AsnC
E3D14_20935	ENOG4105CU9	asparagine synthetase A
E3D14_20940	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
E3D14_20945	ENOG4105DBW	Multi-copper polyphenol oxidoreductase laccase
E3D14_20950	ENOG4105C34	Pseudouridine synthase
E3D14_20955	ENOG4106SNF	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
E3D14_20960	ENOG4107QMW	pyridine nucleotide-disulfide oxidoreductase
E3D14_20970	ENOG4105CEM	UPF0597 protein
E3D14_20975	ENOG4105WWK	YheO domain protein
E3D14_20985	ENOG4105C15	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
E3D14_20990	ENOG4108IIE	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
E3D14_20995	ENOG4108I6A	alcohol dehydrogenase
E3D14_21005	ENOG4105QNF	Outer membrane lipoprotein
E3D14_21010	ENOG4105C8Q	Methyl-accepting chemotaxis
E3D14_21015	ENOG4105DJ4	phosphatidylserine decarboxylase
E3D14_21030	ENOG4105CXT	aspartate transcarbamylase
E3D14_21035	ENOG4108R9M	Involved in allosteric regulation of aspartate carbamoyltransferase (By similarity)
E3D14_21040	ENOG410682Y	Regulates arginine biosynthesis genes (By similarity)
E3D14_21045	ENOG4105CSX	c4-dicarboxylate anaerobic carrier
E3D14_21050	ENOG4105DBV	ornithine carbamoyltransferase
E3D14_21055	ENOG4105C5B	carbamate kinase
E3D14_21080	ENOG4105C8Q	Methyl-accepting chemotaxis
E3D14_21105	ENOG41060NJ	transcriptional regulator
E3D14_21110	ENOG4105CMR	udp-glucose 4-epimerase
E3D14_21115	ENOG4105F0Z	galactose-1-phosphate uridylyltransferase
E3D14_21120	ENOG4105CRD	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P) (By similarity)
E3D14_21125	ENOG4105ENN	converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose (By similarity)
E3D14_21130	ENOG4105CPC	Aldo Keto reductase
E3D14_21135	ENOG4105DWR	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity)
E3D14_21145	ENOG4105K6V	RNA polymerase
E3D14_21155	ENOG4105C75	arginyL-tRNA synthetase
E3D14_21165	ENOG4108R5P	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery (By similarity)
E3D14_21170	ENOG4105C4N	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis (By similarity)
E3D14_21185	ENOG4107QZF	nitrite reductase NADPH large subunit
E3D14_21190	ENOG4105WZK	nitrite reductase NADPH small subunit
E3D14_21195	ENOG4107V9H	nitrite transporter
E3D14_21200	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
E3D14_21205	ENOG4105CJW	magnesium transporter
E3D14_21220	ENOG4108YYX	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. Modulates RNA-binding and helicase activities of the degradosome (By similarity)
E3D14_21225	ENOG4105EX9	Membrane
E3D14_21235	ENOG4105CNG	UPF0061 protein
E3D14_21240	ENOG4105N7H	Cytochrome
E3D14_21245	ENOG4105C9U	ATP-dependent DNA helicase RecQ
E3D14_21250	ENOG4108VUY	thioesterase Superfamily protein
E3D14_21265	ENOG4108RPX	mosc domain containing protein
E3D14_21270	ENOG4105D38	putrescine abc transporter
E3D14_21275	ENOG4105F38	ABC transporter, permease
E3D14_21280	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
E3D14_21285	ENOG4108HM4	ABC transporter
E3D14_21295	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
E3D14_21300	ENOG4105CFQ	glutamine synthetase
E3D14_21305	ENOG4108V7X	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
E3D14_21315	ENOG4108RH0	Crea protein
E3D14_21320	ENOG4105C5I	Dehydrogenase
E3D14_21325	ENOG4105R8A	Heat shock protein
E3D14_21340	ENOG4107R28	alpha amylase, catalytic region
E3D14_21345	ENOG4105C5E	polysaccharide biosynthesis protein
E3D14_21365	ENOG4105X1N	Glycosyl transferase family 8
E3D14_21385	ENOG4105CEY	Amp-dependent synthetase and ligase
E3D14_21390	ENOG4105CHR	reductase
E3D14_21405	ENOG4105F0R	Cytidylyltransferase
E3D14_21415	ENOG4105D2T	synthase
E3D14_21480	ENOG4107R9T	Catalyzes the formation of 5-methyl-uridine at position 54 (m5U54) in all tRNAs (By similarity)
E3D14_21485	ENOG4107EXC	regulatoR
E3D14_21490	ENOG4105JJR	Histidine kinase
E3D14_21500	ENOG4105C6K	Malic enzyme
E3D14_21505	ENOG4105CGD	Nad-dependent epimerase dehydratase
E3D14_21510	ENOG4105VFB	Binds the 23S rRNA (By similarity)
E3D14_21515	ENOG4105C25	Primosomal protein n'
E3D14_21525	ENOG4105XEA	Tetr family transcriptional regulator
E3D14_21535	ENOG4105UYK	outer membrane protein a
E3D14_21540	ENOG4105C7B	Threonine dehydratase
E3D14_21545	ENOG4105C01	Dihydroxy-acid dehydratase
E3D14_21550	ENOG4105CM2	brancheD-chain amino acid aminotransferase
E3D14_21555	ENOG4105P3Y	Acetolactate synthase 2 regulatory subunit
E3D14_21575	ENOG4106HNH	Acyl-transferase
E3D14_21580	ENOG4105EWC	Purine nucleoside phosphorylase
E3D14_21590	ENOG4108RWI	nicotinamidase
E3D14_21595	ENOG4107RH7	Nicotinate phosphoribosyltransferase
E3D14_21600	ENOG4105EHI	Phosphonate ABC transporter, periplasmic
E3D14_21605	ENOG4108VA1	ABC transporter
E3D14_21610	ENOG4105S7S	phosphonate abc transporter
E3D14_21615	ENOG4108Z33	Thiol disulfide Interchange Protein
E3D14_21620	ENOG4105E27	serine threonine protein kinase
E3D14_21630	ENOG4105PC1	Conserved Protein
E3D14_21640	ENOG4108Z6Z	Transcriptional regulator
E3D14_21650	ENOG4107QP2	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
E3D14_21660	ENOG4105DSJ	YicC domain protein
E3D14_21675	ENOG4107J0A	lipopolysaccharide biosynthetic process
E3D14_21690	ENOG4105CG5	Glycosyl transferase (Group 1
E3D14_21695	ENOG4105CUI	Catalyzes the interconversion between ADP-D-glycero- beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose (By similarity)
E3D14_21700	ENOG41062JF	Transcriptional regulator
E3D14_21705	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
E3D14_21710	ENOG4105CPQ	Dehydrogenase
E3D14_21725	ENOG4105C4R	Atp-dependent dna helicase
E3D14_21730	ENOG4105C9B	Cysteine desulfurase
E3D14_21735	ENOG4105P9C	Participates in cysteine desulfuration mediated by SufS. Cysteine desulfuration mobilizes sulfur from L-cysteine to yield L-alanine and constitutes an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules. Functions as a sulfur acceptor for SufS, by mediating the direct transfer of the sulfur atom from the S-sulfanylcysteine of SufS, an intermediate product of cysteine desulfuration process (By similarity)
E3D14_21740	ENOG4105CUZ	uba thif-type nad fad binding protein
E3D14_21770	ENOG4108RR8	protoporphyrinogen oxidase
E3D14_21775	ENOG4105D37	Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA (By similarity)
E3D14_21780	ENOG4108ZK7	protein family UPF0029, Impact, N-terminal protein
E3D14_21785	ENOG4105D9Y	Splits dipeptides with a prolyl residue in the C- terminal position (By similarity)
E3D14_21790	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
E3D14_21795	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
E3D14_21800	ENOG4105CHU	acetyl-coa acetyltransferase
E3D14_21805	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
E3D14_21810	ENOG4105E0F	Histidine kinase
E3D14_21825	ENOG41082K8	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Interacts with IscS and stimulates its activity. Then, accepts a sulfur from IscS and transfers it in turn to TusD (By similarity)
E3D14_21830	ENOG4105M4H	endoribonuclease L-psp
E3D14_21835	ENOG4108ZG0	Ompa motb domain protein
E3D14_21840	ENOG4108R3E	Dna-3-methyladenine glycosylase i
E3D14_21845	ENOG4108HMW	glycyl-tRNA synthetase, alpha subunit
E3D14_21850	ENOG4105C38	Glycyl-tRNA synthetase beta subunit
E3D14_21855	ENOG41090VV	Protein of unknown function (DUF2846)
E3D14_21860	ENOG4105KHV	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
E3D14_21870	ENOG4105BZU	Histidine kinase
E3D14_21875	ENOG41072JS	exoenzyme T
E3D14_21885	ENOG4105CIC	tryptophan-specific transport protein
E3D14_21890	ENOG4105HEE	Binding Domain protein
E3D14_21900	ENOG4108EQM	faD-dependent pyridine nucleotide-disulfide oxidoreductase
E3D14_21905	ENOG4105CNW	domain protein
E3D14_21910	ENOG4108JUA	Transcriptional regulator
E3D14_21915	ENOG4105FDP	GntR family transcriptional regulator
E3D14_21920	ENOG4105CI1	PTS System
E3D14_21925	ENOG4105F8D	glycoside hydrolase family 4
E3D14_21930	ENOG4105ETE	Transcriptional regulator (LacI family
E3D14_21935	ENOG4105CP9	extracellular ligand-binding receptor
E3D14_21940	ENOG4105C32	Amino acid ABC transporter (Permease)
E3D14_21945	ENOG4105CF8	branched-chain amino acid ABC transporter, permease
E3D14_21950	ENOG4105C0Z	ABC transporter
E3D14_21955	ENOG4108IV0	ABC, transporter
E3D14_21970	ENOG4105M78	Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide (By similarity)
E3D14_21985	ENOG4105W0Z	cytoplasmic protein
E3D14_21990	ENOG4107QK7	reductase
E3D14_21995	ENOG4105D3H	Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol (By similarity)
E3D14_22005	ENOG4105C4P	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity)
E3D14_22010	ENOG4105K63	Thioredoxin
E3D14_22015	ENOG4105C1J	atp-dependent rna helicase
E3D14_22020	ENOG4105C9X	ppx gppa phosphatase
E3D14_22030	ENOG4105FFN	Specifically methylates the guanosine in position 1516 of 16S rRNA (By similarity)
E3D14_22040	ENOG4105BZU	Histidine kinase
E3D14_22045	ENOG4105DGW	oligopeptidase A
E3D14_22050	ENOG4105D52	delta-aminolevulinic acid dehydratase
E3D14_22055	ENOG4105F8V	Hydrolase, tatD family
E3D14_22060	ENOG4105DCX	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity)
E3D14_22065	ENOG4105X8U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation (By similarity)
E3D14_22070	ENOG4105WKS	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity)
E3D14_22075	ENOG4105CNK	Required, probably indirectly, for the hydroxylation of 2-octaprenylphenol to 2-octaprenyl-6-hydroxy-phenol, the fourth step in ubiquinone biosynthesis (By similarity)
E3D14_22080	ENOG4105JC1	sterol-binding domain protein
E3D14_22085	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
E3D14_22090	ENOG4105WMR	Protein CrcB homolog
E3D14_22135	ENOG410822N	TonB family
E3D14_22140	ENOG4109015	Biopolymer transport protein exbD tolR
E3D14_22160	ENOG4105VJY	transcriptional regulator
E3D14_22185	ENOG4107XZC	Restriction modification system DNA (Specificity
E3D14_22190	ENOG4105F5W	AtP-binding protein
E3D14_22195	ENOG4105D70	Integrase catalytic subunit
E3D14_22250	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
E3D14_22255	ENOG410804X	Transcriptional regulator
E3D14_22260	ENOG4105E3W	Two component transcriptional regulator (Winged helix family
E3D14_22265	ENOG4105EB3	Histidine kinase
E3D14_22275	ENOG4105CT7	inner membrane cred family protein
E3D14_22280	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
E3D14_22285	ENOG4105KNM	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
E3D14_22290	ENOG4105C4J	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity)
E3D14_22295	ENOG4105J80	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity)
E3D14_22300	ENOG4105CDG	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity)
E3D14_22305	ENOG4107S15	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
E3D14_22310	ENOG4107Z6K	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
E3D14_22315	ENOG4105KY6	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
E3D14_22320	ENOG4105EE4	it plays a direct role in the translocation of protons across the membrane (By similarity)
E3D14_22325	ENOG410684E	atp synthase
E3D14_22330	ENOG4105FA0	parb-like partition protein
E3D14_22335	ENOG4107QJE	Chromosome Partitioning Protein
E3D14_22340	ENOG4105D28	Specifically methylates the N7 position of a guanine in 16S rRNA (By similarity)
E3D14_22345	ENOG4107RE5	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity)
E3D14_22350	ENOG4105QTB	Flavodoxin
E3D14_22355	ENOG4105E0K	tonB-dependent siderophore receptor
E3D14_22360	ENOG4105IBP	Cyclic peptide transporter
E3D14_22365	ENOG4105E0A	ABC, transporter
E3D14_22370	ENOG4105J76	Periplasmic binding protein
E3D14_22375	ENOG4105S6R	Iron-hydroxamate transporter permease subunit
E3D14_22390	ENOG4108IPW	abc transporter atp-binding protein
E3D14_22420	ENOG4105CEY	Amp-dependent synthetase and ligase
E3D14_22430	ENOG4105C0W	non-ribosomal peptide synthetase
E3D14_22445	ENOG4105C1H	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity)
E3D14_22450	ENOG4105DHW	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
E3D14_22455	ENOG4105VAS	Could be involved in insertion of integral membrane proteins into the membrane (By similarity)
E3D14_22460	ENOG4105NVJ	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme (By similarity)
E3D14_22465	ENOG4105VG0	50S ribosomal protein l34
E3D14_22470	ENOG4105CDA	abc transporter atp-binding protein
E3D14_22475	ENOG4105E5Q	amino acid AbC transporter
E3D14_22480	ENOG4105EAB	amino acid AbC transporter
E3D14_22500	ENOG4107SKI	cobyrinic Acid a,c-diamide synthase
E3D14_22510	ENOG4105D5G	Transposase
E3D14_22540	ENOG4105K8R	UPF0145 protein
E3D14_22565	ENOG4105F5W	AtP-binding protein
E3D14_22570	ENOG4105D70	Integrase catalytic subunit
E3D14_22615	ENOG4107QJE	Chromosome Partitioning Protein
E3D14_22740	ENOG4105D5G	Transposase
E3D14_22760	ENOG4105EQR	Transposase IS116 IS110 IS902
E3D14_22800	ENOG41066XE	Type III export protein
E3D14_22830	ENOG4108KB1	transcriptional regulator, arac family
E3D14_22845	ENOG4106V6P	Exoenzyme S synthesis protein C
E3D14_22970	ENOG4107U2T	alpha beta
E3D14_22975	ENOG4105D5G	Transposase
E3D14_22980	ENOG4105F5W	AtP-binding protein
E3D14_22985	ENOG4105D70	Integrase catalytic subunit
E3D14_23105	ENOG4105F2I	Transposase
E3D14_23185	ENOG4105DND	Transcriptional regulator
E3D14_23250	ENOG4108KTG	Membrane protein, drug metabolite transporter
E3D14_23335	ENOG4108C33	Resolvase
E3D14_23400	ENOG4105W5Q	DNA repair protein (RadC
E3D14_23440	ENOG4105D70	Integrase catalytic subunit
E3D14_23445	ENOG4105F5W	AtP-binding protein
E3D14_23455	ENOG4107635	Hok Gef family protein
E3D14_23475	ENOG4105DIJ	Phosphoethanolamine transferase
E3D14_23480	ENOG4105DIJ	Phosphoethanolamine transferase
E3D14_23490	ENOG4108C33	Resolvase
E3D14_23500	ENOG4107SKI	cobyrinic Acid a,c-diamide synthase
E3D14_23725	ENOG4105W5Q	DNA repair protein (RadC
E3D14_23770	ENOG41069I7	
E3D14_23840	ENOG4105F9F	transposase
E3D14_23920	ENOG4105EQR	Transposase IS116 IS110 IS902