locus-tag	class	description
KXJ75_00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
KXJ75_00010	COG0592	DNA-directed DNA polymerase activity
KXJ75_00025	COG2207	Transcriptional regulator
KXJ75_00030	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
KXJ75_00040	COG0071	Belongs to the small heat shock protein (HSP20) family
KXJ75_00045	COG3977	Valine--pyruvate aminotransferase
KXJ75_00060	COG2814	Major facilitator Superfamily
KXJ75_00065	COG0745	RESPONSE REGULATOR receiver
KXJ75_00070	COG2205	protein histidine kinase activity
KXJ75_00090	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
KXJ75_00095	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KXJ75_00095	COG4191	Histidine kinase
KXJ75_00100	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
KXJ75_00105	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KXJ75_00110	COG1309	transcriptional regulator
KXJ75_00140	COG0561	phosphatase activity
KXJ75_00145	COG2267	carboxylic ester hydrolase activity
KXJ75_00150	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KXJ75_00155	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
KXJ75_00160	COG1758	RNA polymerase activity
KXJ75_00175	COG0859	PFAM glycosyl transferase family 9
KXJ75_00180	COG3642	lipopolysaccharide core region biosynthetic process
KXJ75_00225	COG0589	response to stress
KXJ75_00230	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
KXJ75_00235	COG2199	diguanylate cyclase activity
KXJ75_00240	COG1528	Iron-storage protein
KXJ75_00245	COG2081	HI0933 family
KXJ75_00250	COG2223	nitrite transmembrane transporter activity
KXJ75_00255	COG1280	lysine exporter protein (LysE YggA)
KXJ75_00260	COG3275	phosphorelay sensor kinase activity
KXJ75_00265	COG3279	Response regulator of the LytR AlgR family
KXJ75_00270	COG2223	nitrite transmembrane transporter activity
KXJ75_00275	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
KXJ75_00280	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
KXJ75_00290	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
KXJ75_00350	COG0789	Transcriptional regulator
KXJ75_00375	COG0789	Transcriptional regulator
KXJ75_00485	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
KXJ75_00490	COG2166	iron-sulfur cluster assembly
KXJ75_00495	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
KXJ75_00500	COG0210	DNA helicase
KXJ75_00515	COG1063	alcohol dehydrogenase
KXJ75_00520	COG0156	8-amino-7-oxononanoate synthase activity
KXJ75_00530	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
KXJ75_00535	COG0438	transferase activity, transferring glycosyl groups
KXJ75_00540	COG3307	-O-antigen
KXJ75_00575	COG1580	Controls the rotational direction of flagella during chemotaxis
KXJ75_00580	COG3161	chorismate lyase activity
KXJ75_00585	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
KXJ75_00590	COG2937	Belongs to the GPAT DAPAT family
KXJ75_00595	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
KXJ75_00610	COG0534	Mate efflux family protein
KXJ75_00615	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
KXJ75_00620	COG2205	protein histidine kinase activity
KXJ75_00625	COG0745	RESPONSE REGULATOR receiver
KXJ75_00635	COG1045	serine acetyltransferase
KXJ75_00645	COG3074	FtsZ-dependent cytokinesis
KXJ75_00650	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
KXJ75_00655	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
KXJ75_00655	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
KXJ75_00660	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
KXJ75_00700	COG1609	Transcriptional regulator
KXJ75_00715	COG1484	DNA-dependent DNA replication
KXJ75_00720	COG4584	PFAM Integrase catalytic
KXJ75_00730	COG1609	Transcriptional regulator
KXJ75_00735	COG0385	Bile acid
KXJ75_00765	COG1262	PFAM Formylglycine-generating sulfatase enzyme
KXJ75_00785	COG0583	DNA-binding transcription factor activity
KXJ75_00795	COG1079	Belongs to the binding-protein-dependent transport system permease family
KXJ75_00800	COG4603	Belongs to the binding-protein-dependent transport system permease family
KXJ75_00805	COG3845	ABC transporter
KXJ75_00810	COG1744	ABC transporter substrate-binding protein PnrA-like
KXJ75_00815	COG0210	DNA helicase
KXJ75_00835	COG3335	DDE superfamily endonuclease
KXJ75_00890	COG1943	Transposase
KXJ75_00895	COG0583	DNA-binding transcription factor activity
KXJ75_00965	COG1280	lysine exporter protein (LysE YggA)
KXJ75_00980	COG2962	Rard protein
KXJ75_00990	COG1012	belongs to the aldehyde dehydrogenase family
KXJ75_00995	COG1396	sequence-specific DNA binding
KXJ75_01000	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
KXJ75_01010	COG0519	Catalyzes the synthesis of GMP from XMP
KXJ75_01010	COG0518	GMP synthase (glutamine-hydrolyzing) activity
KXJ75_01020	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KXJ75_01030	COG2221	Nitrite and sulphite reductase 4Fe-4S
KXJ75_01030	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
KXJ75_01040	COG1322	Protein conserved in bacteria
KXJ75_01045	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
KXJ75_01050	COG0569	domain protein
KXJ75_01055	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
KXJ75_01055	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
KXJ75_01060	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
KXJ75_01065	COG0242	peptide deformylase activity
KXJ75_01075	COG0758	DNA mediated transformation
KXJ75_01080	COG2922	Belongs to the Smg family
KXJ75_01085	COG0551	DNA topoisomerase type I activity
KXJ75_01090	COG0009	L-threonylcarbamoyladenylate synthase
KXJ75_01095	COG0408	coproporphyrinogen oxidase activity
KXJ75_01110	COG0218	Necessary for normal cell division and for the maintenance of normal septation
KXJ75_01125	COG3078	GTPase activator activity
KXJ75_01135	COG0635	Involved in the biosynthesis of porphyrin-containing compound
KXJ75_01140	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
KXJ75_01145	COG2204	response regulator
KXJ75_01150	COG3852	Histidine kinase
KXJ75_01165	COG0174	glutamine synthetase
KXJ75_01170	COG1217	gtp-binding protein TYPA
KXJ75_01175	COG1295	ribonuclease BN
KXJ75_01180	COG1490	D-aminoacyl-tRNA deacylase activity
KXJ75_01185	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
KXJ75_01195	COG0456	acetyltransferase
KXJ75_01205	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
KXJ75_01210	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KXJ75_01215	COG2610	gluconate transmembrane transporter activity
KXJ75_01220	COG3265	gluconokinase activity
KXJ75_01225	COG0129	dihydroxy-acid dehydratase activity
KXJ75_01230	COG0800	Aldolase
KXJ75_01245	COG1609	Transcriptional regulator
KXJ75_01260	COG4942	peptidase
KXJ75_01265	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
KXJ75_01270	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KXJ75_01275	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
KXJ75_01280	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
KXJ75_01285	COG0316	Belongs to the HesB IscA family
KXJ75_01285	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
KXJ75_01290	COG1040	competence protein
KXJ75_01295	COG0596	Alpha beta hydrolase
KXJ75_01310	COG2183	response to ionizing radiation
KXJ75_01315	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
KXJ75_01325	COG2205	protein histidine kinase activity
KXJ75_01335	COG0051	transcription antitermination factor activity, RNA binding
KXJ75_01340	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
KXJ75_01345	COG0088	Forms part of the polypeptide exit tunnel
KXJ75_01350	COG0089	rRNA binding
KXJ75_01355	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
KXJ75_01360	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
KXJ75_01365	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
KXJ75_01370	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
KXJ75_01375	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
KXJ75_01380	COG0255	Belongs to the universal ribosomal protein uL29 family
KXJ75_01385	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
KXJ75_01390	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
KXJ75_01395	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
KXJ75_01400	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
KXJ75_01405	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
KXJ75_01410	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
KXJ75_01415	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
KXJ75_01420	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
KXJ75_01425	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
KXJ75_01430	COG1841	ribosomal large subunit assembly
KXJ75_01435	COG0200	Binds to the 23S rRNA
KXJ75_01440	COG0201	protein transport
KXJ75_01445	COG0257	Belongs to the bacterial ribosomal protein bL36 family
KXJ75_01450	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
KXJ75_01455	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
KXJ75_01460	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
KXJ75_01465	COG0202	RNA polymerase activity
KXJ75_01470	COG0203	ribosomal protein L17
KXJ75_01520	COG2249	NAD(P)H dehydrogenase (quinone) activity
KXJ75_01535	COG1770	oligopeptidase
KXJ75_01540	COG2358	TRAP transporter, solute receptor (TAXI family
KXJ75_01555	COG3714	YhhN family
KXJ75_01580	COG1301	dicarboxylic acid transport
KXJ75_01590	COG2095	MarC family integral membrane protein
KXJ75_01610	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
KXJ75_01620	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
KXJ75_01630	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KXJ75_01655	COG0742	ribosomal rna small subunit methyltransferase
KXJ75_01660	COG0552	protein localization to endoplasmic reticulum
KXJ75_01665	COG2884	Cell division ATP-binding protein ftsE
KXJ75_01670	COG2177	Part of the ABC transporter FtsEX involved in
KXJ75_01685	COG0288	reversible hydration of carbon dioxide
KXJ75_01690	COG2188	Transcriptional regulator
KXJ75_01695	COG1228	amidohydrolase
KXJ75_01700	COG0010	Belongs to the arginase family
KXJ75_01705	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
KXJ75_01710	COG2986	histidine ammonia-lyase
KXJ75_01715	COG0387	Pfam Sodium calcium exchanger
KXJ75_01725	COG2199	diguanylate cyclase activity
KXJ75_01725	COG2200	EAL domain
KXJ75_01725	COG2202	Pas domain
KXJ75_01780	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
KXJ75_01830	COG1077	Cell shape determining protein MreB Mrl
KXJ75_01835	COG1792	Involved in formation and maintenance of cell shape
KXJ75_01840	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
KXJ75_01845	COG0424	maF-like protein
KXJ75_01850	COG1530	ribonuclease E activity
KXJ75_01860	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
KXJ75_01865	COG0312	modulator of DNA gyrase
KXJ75_01890	COG0477	Major facilitator Superfamily
KXJ75_01930	COG0189	ligase activity
KXJ75_01940	COG0642	Histidine kinase
KXJ75_01945	COG0745	RESPONSE REGULATOR receiver
KXJ75_01960	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
KXJ75_01965	COG0352	thiamine-phosphate diphosphorylase activity
KXJ75_01970	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
KXJ75_01980	COG2022	thiamine diphosphate biosynthetic process
KXJ75_01985	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
KXJ75_02010	COG3932	Exopolysaccharide synthesis, ExoD
KXJ75_02025	COG1733	regulation of RNA biosynthetic process
KXJ75_02055	COG1214	PFAM Peptidase M22, glycoprotease
KXJ75_02055	COG0456	acetyltransferase
KXJ75_02075	COG1494	fructose-1,6-bisphosphatase
KXJ75_02085	COG3071	HemY protein
KXJ75_02090	COG2959	enzyme of heme biosynthesis
KXJ75_02105	COG3072	Adenylate cyclase
KXJ75_02110	COG0400	carboxylic ester hydrolase activity
KXJ75_02115	COG1965	Belongs to the frataxin family
KXJ75_02125	COG0019	diaminopimelate decarboxylase activity
KXJ75_02130	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
KXJ75_02145	COG1011	Hydrolase
KXJ75_02155	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
KXJ75_02160	COG0561	phosphatase activity
KXJ75_02175	COG1058	Belongs to the CinA family
KXJ75_02175	COG1546	Belongs to the CinA family
KXJ75_02185	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
KXJ75_02195	COG1522	sequence-specific DNA binding
KXJ75_02200	COG1368	sulfuric ester hydrolase activity
KXJ75_02230	COG4221	oxidoreductase activity
KXJ75_02245	COG1979	alcohol dehydrogenase
KXJ75_02255	COG2873	o-acetylhomoserine
KXJ75_02285	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
KXJ75_02295	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
KXJ75_02300	COG2949	membrane
KXJ75_02315	COG1441	menaquinone biosynthetic process
KXJ75_02320	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
KXJ75_02325	COG0596	Alpha beta hydrolase
KXJ75_02330	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
KXJ75_02335	COG1169	isochorismate synthase
KXJ75_02340	COG1575	Belongs to the MenA family. Type 1 subfamily
KXJ75_02350	COG1966	Carbon starvation protein
KXJ75_02355	COG2879	small protein
KXJ75_02360	COG0523	cobalamin synthesis protein
KXJ75_02385	COG0513	Belongs to the DEAD box helicase family
KXJ75_02395	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
KXJ75_02400	COG1671	Belongs to the UPF0178 family
KXJ75_02425	COG3722	fumarate hydratase activity
KXJ75_02430	COG0246	Mannitol dehydrogenase
KXJ75_02435	COG2213	PTS system mannitol-specific
KXJ75_02435	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
KXJ75_02445	COG4776	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction
KXJ75_02455	COG2823	Periplasmic or secreted lipoprotein
KXJ75_02460	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
KXJ75_02465	COG0792	nuclease activity
KXJ75_02470	COG3107	peptidoglycan biosynthetic process
KXJ75_02475	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
KXJ75_02485	COG2001	Belongs to the MraZ family
KXJ75_02490	COG0275	rRNA processing
KXJ75_02495	COG3116	cell division
KXJ75_02500	COG0768	penicillin binding
KXJ75_02510	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
KXJ75_02515	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
KXJ75_02520	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
KXJ75_02525	COG0772	Belongs to the SEDS family
KXJ75_02530	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
KXJ75_02535	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
KXJ75_02540	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
KXJ75_02545	COG0849	cell division
KXJ75_02550	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
KXJ75_02555	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
KXJ75_02565	COG0653	protein targeting
KXJ75_02575	COG0494	nUDIX hydrolase
KXJ75_02580	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
KXJ75_02585	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
KXJ75_02600	COG1459	type II secretion system
KXJ75_02605	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
KXJ75_02640	COG2186	Transcriptional regulator
KXJ75_02645	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
KXJ75_02650	COG0508	dehydrogenase complex catalyzes the overall conversion of
KXJ75_02655	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
KXJ75_02660	COG5002	protein histidine kinase activity
KXJ75_02660	COG5001	Diguanylate cyclase
KXJ75_02660	COG3447	MASE1 domain protein
KXJ75_02675	COG0840	transmembrane signaling receptor activity
KXJ75_02685	COG1049	propionate catabolic process, 2-methylcitrate cycle
KXJ75_02690	COG2200	EAL domain
KXJ75_02700	COG1280	lysine exporter protein (LysE YggA)
KXJ75_02710	COG0523	cobalamin synthesis protein
KXJ75_02715	COG0477	Major facilitator Superfamily
KXJ75_02730	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
KXJ75_02735	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
KXJ75_02770	COG5433	transposase activity
KXJ75_02780	COG5006	permease, DMT superfamily
KXJ75_02785	COG1522	sequence-specific DNA binding
KXJ75_02790	COG0110	maltose O-acetyltransferase activity
KXJ75_02795	COG0366	Alpha amylase catalytic
KXJ75_02800	COG1263	PTS System
KXJ75_02800	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KXJ75_02805	COG1609	Transcriptional regulator
KXJ75_02820	COG0252	asparaginase activity
KXJ75_02835	COG1803	Methylglyoxal synthase
KXJ75_02860	COG1444	tRNA N-acetyltransferase activity
KXJ75_02865	COG1565	acr, cog1565
KXJ75_02865	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
KXJ75_02875	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
KXJ75_02905	COG0109	protoheme IX farnesyltransferase activity
KXJ75_02910	COG1012	belongs to the aldehyde dehydrogenase family
KXJ75_02915	COG1177	transmembrane transport
KXJ75_02920	COG1176	ABC-type spermidine putrescine transport system, permease component I
KXJ75_02925	COG3842	ATPase activity
KXJ75_02930	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
KXJ75_02935	COG0583	DNA-binding transcription factor activity
KXJ75_02940	COG1757	Na H antiporter
KXJ75_02985	COG0297	glycogen (starch) synthase activity
KXJ75_02990	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
KXJ75_02995	COG2813	Specifically methylates the guanine in position
KXJ75_03000	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
KXJ75_03005	COG2203	Gaf domain
KXJ75_03005	COG3706	GGDEF domain
KXJ75_03005	COG4251	negative regulation of phosphorylation
KXJ75_03005	COG5001	Diguanylate cyclase
KXJ75_03010	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
KXJ75_03020	COG2995	paraquat-inducible protein a
KXJ75_03025	COG3008	intermembrane lipid transfer
KXJ75_03025	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
KXJ75_03030	COG3009	Protein conserved in bacteria
KXJ75_03040	COG3240	lipase activity
KXJ75_03055	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
KXJ75_03070	COG3409	Peptidoglycan-binding domain 1 protein
KXJ75_03070	COG3267	Type II secretory pathway component ExeA
KXJ75_03075	COG0617	tRNA 3'-terminal CCA addition
KXJ75_03080	COG0306	phosphate transporter
KXJ75_03085	COG1392	Phosphate transport regulator
KXJ75_03095	COG3133	Outer membrane lipoprotein
KXJ75_03100	COG0456	acetyltransferase
KXJ75_03115	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
KXJ75_03120	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
KXJ75_03130	COG3031	protein transport across the cell outer membrane
KXJ75_03140	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
KXJ75_03145	COG1459	type II secretion system
KXJ75_03150	COG2165	general secretion pathway protein
KXJ75_03160	COG2165	general secretion pathway protein
KXJ75_03165	COG4795	General secretion pathway protein
KXJ75_03170	COG3156	type II secretion system protein K
KXJ75_03180	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
KXJ75_03195	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
KXJ75_03200	COG1011	Hydrolase
KXJ75_03205	COG0494	nUDIX hydrolase
KXJ75_03210	COG1218	3'(2'),5'-bisphosphate nucleotidase
KXJ75_03215	COG0814	amino acid
KXJ75_03220	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KXJ75_03225	COG3708	Transcriptional regulator
KXJ75_03225	COG2207	Transcriptional regulator
KXJ75_03235	COG0626	cystathionine gamma-synthase activity
KXJ75_03250	COG1380	Effector of murein hydrolase LrgA
KXJ75_03300	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
KXJ75_03310	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
KXJ75_03320	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
KXJ75_03325	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
KXJ75_03335	COG0137	argininosuccinate synthase activity
KXJ75_03350	COG0583	DNA-binding transcription factor activity
KXJ75_03375	COG0110	maltose O-acetyltransferase activity
KXJ75_03380	COG3174	membrane
KXJ75_03385	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KXJ75_03390	COG1126	abc transporter atp-binding protein
KXJ75_03395	COG0765	amino acid transport
KXJ75_03400	COG0765	amino acid transport
KXJ75_03420	COG1028	Short-chain dehydrogenase reductase Sdr
KXJ75_03425	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
KXJ75_03440	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
KXJ75_03445	COG4991	sh3 domain protein
KXJ75_03455	COG2816	NAD+ diphosphatase activity
KXJ75_03460	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
KXJ75_03465	COG1940	carbohydrate kinase activity
KXJ75_03470	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
KXJ75_03475	COG0126	phosphoglycerate kinase activity
KXJ75_03480	COG0191	fructose-bisphosphate aldolase activity
KXJ75_03485	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KXJ75_03525	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
KXJ75_03535	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
KXJ75_03540	COG1595	DNA-templated transcription, initiation
KXJ75_03560	COG0481	GTPase activity
KXJ75_03565	COG0681	Belongs to the peptidase S26 family
KXJ75_03570	COG0571	ribonuclease III activity
KXJ75_03580	COG1381	Involved in DNA repair and RecF pathway recombination
KXJ75_03585	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
KXJ75_03590	COG3023	N-Acetylmuramoyl-L-alanine amidase
KXJ75_03595	COG4807	Protein conserved in bacteria
KXJ75_03605	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
KXJ75_03610	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
KXJ75_03615	COG3956	TIGRFAM MazG family protein
KXJ75_03620	COG0504	CTP synthase activity
KXJ75_03625	COG0148	phosphopyruvate hydratase activity
KXJ75_03630	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
KXJ75_03635	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
KXJ75_03645	COG0585	pseudouridine synthase activity
KXJ75_03650	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
KXJ75_03655	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
KXJ75_03660	COG1238	metal cluster binding
KXJ75_03665	COG4942	peptidase
KXJ75_03665	COG1388	LysM domain
KXJ75_03675	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
KXJ75_03680	COG0828	Belongs to the bacterial ribosomal protein bS21 family
KXJ75_03685	COG1610	YqeY-like protein
KXJ75_03690	COG0358	DNA primase activity
KXJ75_03695	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
KXJ75_03720	COG0151	Belongs to the GarS family
KXJ75_03725	COG0138	bifunctional purine biosynthesis protein purh
KXJ75_03735	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
KXJ75_03740	COG3036	rescue of stalled ribosome
KXJ75_03750	COG0635	Involved in the biosynthesis of porphyrin-containing compound
KXJ75_03755	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
KXJ75_03770	COG0673	inositol 2-dehydrogenase activity
KXJ75_03780	COG1585	Membrane protein implicated in regulation of membrane protease activity
KXJ75_03785	COG0330	HflC and HflK could
KXJ75_03790	COG1648	precorrin-2 dehydrogenase activity
KXJ75_03790	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
KXJ75_03795	COG0175	sulfate reduction
KXJ75_03800	COG2895	sulfate adenylyltransferase (ATP) activity
KXJ75_03805	COG0471	metal ion transport
KXJ75_03805	COG3273	potassium ion transport
KXJ75_03810	COG0529	Catalyzes the synthesis of activated sulfate
KXJ75_03845	COG3039	Transposase
KXJ75_03890	COG1136	(ABC) transporter
KXJ75_03905	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
KXJ75_03920	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
KXJ75_03925	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
KXJ75_03930	COG0163	prenyltransferase activity
KXJ75_03950	COG1131	(ABC) transporter
KXJ75_03955	COG0842	Transport permease protein
KXJ75_03970	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
KXJ75_03975	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
KXJ75_03995	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
KXJ75_04000	COG1489	DNA binding
KXJ75_04010	COG1643	Atp-dependent helicase
KXJ75_04015	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
KXJ75_04020	COG0346	lactoylglutathione lyase activity
KXJ75_04030	COG2076	Multidrug Resistance protein
KXJ75_04035	COG0583	DNA-binding transcription factor activity
KXJ75_04045	COG0671	phosphoesterase, PA-phosphatase related
KXJ75_04060	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
KXJ75_04065	COG0038	chloride channel
KXJ75_04075	COG0316	Belongs to the HesB IscA family
KXJ75_04155	COG3039	Transposase
KXJ75_04185	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
KXJ75_04195	COG1401	restriction endodeoxyribonuclease activity
KXJ75_04195	COG1401	restriction endodeoxyribonuclease activity
KXJ75_04205	COG0732	type I restriction modification DNA specificity domain
KXJ75_04210	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
KXJ75_04220	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
KXJ75_04245	COG2003	Belongs to the UPF0758 family
KXJ75_04280	COG3311	Transcriptional regulator
KXJ75_04340	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
KXJ75_04355	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KXJ75_04385	COG0745	RESPONSE REGULATOR receiver
KXJ75_04390	COG3104	oligopeptide transport
KXJ75_04395	COG1210	Utp--glucose-1-phosphate uridylyltransferase
KXJ75_04400	COG1555	photosystem II stabilization
KXJ75_04410	COG2350	Protein conserved in bacteria
KXJ75_04415	COG2917	probably involved in intracellular septation
KXJ75_04420	COG0076	glutamate decarboxylase activity
KXJ75_04425	COG1272	protein, Hemolysin III
KXJ75_04430	COG0569	domain protein
KXJ75_04430	COG2985	domain, Protein
KXJ75_04445	COG0477	Major facilitator Superfamily
KXJ75_04450	COG0583	DNA-binding transcription factor activity
KXJ75_04455	COG3227	Zinc metalloprotease (Elastase)
KXJ75_04460	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KXJ75_04465	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KXJ75_04485	COG0668	transmembrane transport
KXJ75_04490	COG1376	ErfK ybiS ycfS ynhG family protein
KXJ75_04495	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KXJ75_04525	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
KXJ75_04535	COG0488	(ABC) transporter
KXJ75_04540	COG0516	GMP reductase activity
KXJ75_04540	COG0517	IMP dehydrogenase activity
KXJ75_04550	COG0784	Response regulator, receiver
KXJ75_04550	COG0835	chemotaxis
KXJ75_04555	COG2755	lipolytic protein G-D-S-L family
KXJ75_04560	COG4181	ATPase activity
KXJ75_04570	COG1090	epimerase
KXJ75_04575	COG2200	EAL domain
KXJ75_04580	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KXJ75_04585	COG4935	Belongs to the peptidase S8 family
KXJ75_04585	COG2234	aminopeptidase activity
KXJ75_04590	COG0220	tRNA (guanine-N7-)-methyltransferase activity
KXJ75_04595	COG3171	Protein conserved in bacteria
KXJ75_04600	COG2066	Belongs to the glutaminase family
KXJ75_04605	COG2897	thiosulfate sulfurtransferase activity
KXJ75_04645	COG0582	viral genome integration into host DNA
KXJ75_04660	COG4974	Belongs to the 'phage' integrase family
KXJ75_04685	COG3039	Transposase
KXJ75_04740	COG3076	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome
KXJ75_04745	COG3300	MHYT domain
KXJ75_04745	COG5001	Diguanylate cyclase
KXJ75_04765	COG4628	conserved protein (DUF2132)
KXJ75_04770	COG0688	phosphatidylethanolamine metabolic process
KXJ75_04780	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
KXJ75_04820	COG1278	Cold shock
KXJ75_04830	COG0840	transmembrane signaling receptor activity
KXJ75_04835	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
KXJ75_04870	COG1484	DNA-dependent DNA replication
KXJ75_04875	COG4584	PFAM Integrase catalytic
KXJ75_04900	COG0848	biopolymer transport protein
KXJ75_04905	COG0811	peptide transport
KXJ75_04910	COG0811	peptide transport
KXJ75_04920	COG4206	TonB-dependent receptor
KXJ75_04935	COG4174	ABC transporter (Permease)
KXJ75_04940	COG4239	(ABC) transporter, permease
KXJ75_04945	COG0747	negative chemotaxis
KXJ75_04950	COG0444	Belongs to the ABC transporter superfamily
KXJ75_04955	COG4608	Belongs to the ABC transporter superfamily
KXJ75_04960	COG2195	Cleaves the N-terminal amino acid of tripeptides
KXJ75_04965	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
KXJ75_04970	COG1073	alpha beta
KXJ75_04985	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
KXJ75_05025	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
KXJ75_05025	COG1116	anion transmembrane transporter activity
KXJ75_05030	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
KXJ75_05035	COG1116	anion transmembrane transporter activity
KXJ75_05040	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
KXJ75_05040	COG2146	nitrite reductase [NAD(P)H] activity
KXJ75_05045	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
KXJ75_05045	COG2146	nitrite reductase [NAD(P)H] activity
KXJ75_05050	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KXJ75_05055	COG2313	pseudouridylate synthase activity
KXJ75_05115	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
KXJ75_05120	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
KXJ75_05135	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
KXJ75_05145	COG2986	histidine ammonia-lyase
KXJ75_05170	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
KXJ75_05180	COG1028	Short-chain dehydrogenase reductase Sdr
KXJ75_05195	COG0521	Mo-molybdopterin cofactor biosynthetic process
KXJ75_05220	COG2966	Psort location CytoplasmicMembrane, score
KXJ75_05225	COG3610	response to peptide
KXJ75_05235	COG0175	sulfate reduction
KXJ75_05240	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
KXJ75_05245	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
KXJ75_05255	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
KXJ75_05270	COG5001	Diguanylate cyclase
KXJ75_05295	COG3139	Protein of unknown function (DUF1315)
KXJ75_05320	COG0616	signal peptide processing
KXJ75_05325	COG1902	pentaerythritol trinitrate reductase activity
KXJ75_05325	COG0446	pyridine nucleotide-disulphide oxidoreductase
KXJ75_05330	COG0778	Nitroreductase
KXJ75_05340	COG2264	protein methyltransferase activity
KXJ75_05350	COG0583	DNA-binding transcription factor activity
KXJ75_05355	COG2190	(PTS) system
KXJ75_05355	COG1263	PTS System
KXJ75_05355	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KXJ75_05360	COG4145	pantothenate transmembrane transporter activity
KXJ75_05370	COG0439	Biotin carboxylase
KXJ75_05375	COG0511	ligase activity, forming carbon-carbon bonds
KXJ75_05380	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
KXJ75_05385	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
KXJ75_05405	COG3381	protein complex oligomerization
KXJ75_05415	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
KXJ75_05420	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
KXJ75_05440	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
KXJ75_05445	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
KXJ75_05450	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
KXJ75_05455	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
KXJ75_05460	COG4172	Belongs to the ABC transporter superfamily
KXJ75_05470	COG0601	transmembrane transport
KXJ75_05480	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
KXJ75_05485	COG0142	geranyltranstransferase activity
KXJ75_05495	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
KXJ75_05500	COG1360	Flagellar Motor Protein
KXJ75_05515	COG1534	Rna-binding protein
KXJ75_05520	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
KXJ75_05530	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
KXJ75_05535	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
KXJ75_05540	COG0149	triose-phosphate isomerase activity
KXJ75_05545	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
KXJ75_05560	COG0779	Required for maturation of 30S ribosomal subunits
KXJ75_05565	COG0195	Participates in both transcription termination and antitermination
KXJ75_05570	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
KXJ75_05575	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
KXJ75_05580	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
KXJ75_05585	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
KXJ75_05590	COG1185	polyribonucleotide nucleotidyltransferase activity
KXJ75_05600	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
KXJ75_05610	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
KXJ75_05615	COG0826	peptidase U32
KXJ75_05630	COG0312	modulator of DNA gyrase
KXJ75_05635	COG0312	modulator of DNA gyrase
KXJ75_05650	COG4974	Belongs to the 'phage' integrase family
KXJ75_05660	COG1970	mechanosensitive ion channel activity
KXJ75_05670	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
KXJ75_05675	COG0789	Transcriptional regulator
KXJ75_05695	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
KXJ75_05705	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
KXJ75_05710	COG0321	lipoyl(octanoyl) transferase activity
KXJ75_05715	COG2921	Belongs to the UPF0250 family
KXJ75_05720	COG1686	Belongs to the peptidase S11 family
KXJ75_05725	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
KXJ75_05730	COG2951	lytic endotransglycosylase activity
KXJ75_05735	COG0772	Belongs to the SEDS family
KXJ75_05740	COG0768	penicillin binding
KXJ75_05745	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
KXJ75_05750	COG0799	negative regulation of ribosome biogenesis
KXJ75_05755	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
KXJ75_05770	COG0495	leucyl-tRNA aminoacylation
KXJ75_05775	COG2888	peptidyl-tyrosine sulfation
KXJ75_05785	COG0815	Transfers the fatty acyl group on membrane lipoproteins
KXJ75_05790	COG4535	Mg2 and Co2 transporter CorC
KXJ75_05795	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
KXJ75_05800	COG1702	phosphate starvation-inducible protein PhoH
KXJ75_05810	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
KXJ75_05825	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
KXJ75_05840	COG2199	diguanylate cyclase activity
KXJ75_05860	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
KXJ75_05870	COG0516	GMP reductase activity
KXJ75_05880	COG0642	Histidine kinase
KXJ75_05920	COG3214	Protein conserved in bacteria
KXJ75_05925	COG3080	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
KXJ75_05930	COG3029	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
KXJ75_05935	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
KXJ75_05940	COG1053	succinate dehydrogenase
KXJ75_05950	COG0584	glycerophosphoryl diester phosphodiesterase
KXJ75_05955	COG3264	Mechanosensitive ion channel
KXJ75_05955	COG1511	domain protein
KXJ75_05965	COG0739	heme binding
KXJ75_05975	COG3121	Chaperone
KXJ75_06000	COG0583	DNA-binding transcription factor activity
KXJ75_06015	COG0583	DNA-binding transcription factor activity
KXJ75_06020	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
KXJ75_06055	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
KXJ75_06060	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
KXJ75_06070	COG0338	D12 class N6 adenine-specific DNA methyltransferase
KXJ75_06075	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
KXJ75_06085	COG0180	Tryptophanyl-tRNA synthetase
KXJ75_06100	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
KXJ75_06110	COG1012	belongs to the aldehyde dehydrogenase family
KXJ75_06125	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
KXJ75_06135	COG0657	acetylesterase activity
KXJ75_06140	COG3097	Belongs to the UPF0267 family
KXJ75_06150	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
KXJ75_06160	COG0471	metal ion transport
KXJ75_06160	COG0490	domain, Protein
KXJ75_06305	COG5569	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KXJ75_06330	COG3039	Transposase
KXJ75_06340	COG0739	heme binding
KXJ75_06375	COG2205	protein histidine kinase activity
KXJ75_06380	COG0745	RESPONSE REGULATOR receiver
KXJ75_06385	COG1276	copper resistance
KXJ75_06390	COG2372	response to copper ion
KXJ75_06395	COG3667	copper resistance
KXJ75_06400	COG2132	Multicopper oxidase
KXJ75_06415	COG1484	DNA-dependent DNA replication
KXJ75_06430	COG0582	viral genome integration into host DNA
KXJ75_06435	COG0012	GTP binding
KXJ75_06440	COG0193	aminoacyl-tRNA hydrolase activity
KXJ75_06445	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
KXJ75_06455	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
KXJ75_06460	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
KXJ75_06465	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
KXJ75_06485	COG2912	Transglutaminase-like superfamily
KXJ75_06490	COG2877	3-deoxy-8-phosphooctulonate synthase activity
KXJ75_06520	COG3445	Acts as a radical domain for damaged PFL and possibly other radical proteins
KXJ75_06530	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
KXJ75_06545	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
KXJ75_06550	COG1115	amino acid carrier protein
KXJ75_06565	COG0714	Associated with various cellular activities
KXJ75_06575	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
KXJ75_06590	COG0189	ligase activity
KXJ75_06595	COG1385	rRNA (uridine-N3-)-methyltransferase activity
KXJ75_06605	COG3091	SprT-like family
KXJ75_06615	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
KXJ75_06625	COG0251	oxidation-reduction process
KXJ75_06650	COG0739	heme binding
KXJ75_06655	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
KXJ75_06665	COG1881	PFAM PEBP family protein
KXJ75_06670	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
KXJ75_06675	COG0583	DNA-binding transcription factor activity
KXJ75_06700	COG0583	DNA-binding transcription factor activity
KXJ75_06705	COG1028	Short-chain dehydrogenase reductase Sdr
KXJ75_06710	COG0616	signal peptide processing
KXJ75_06715	COG3724	N-succinylarginine dihydrolase activity
KXJ75_06735	COG0840	transmembrane signaling receptor activity
KXJ75_06765	COG4608	Belongs to the ABC transporter superfamily
KXJ75_06770	COG0444	Belongs to the ABC transporter superfamily
KXJ75_06775	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KXJ75_06795	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
KXJ75_06860	COG2132	Multicopper oxidase
KXJ75_06905	COG1677	Flagellar hook-basal body complex protein FliE
KXJ75_06915	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
KXJ75_06975	COG1684	flagellar biosynthetic protein fliR
KXJ75_06985	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
KXJ75_07010	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
KXJ75_07015	COG0643	Histidine kinase
KXJ75_07015	COG0784	Response regulator, receiver
KXJ75_07015	COG2198	Histidine kinase
KXJ75_07020	COG2201	protein-glutamate methylesterase activity
KXJ75_07025	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
KXJ75_07030	COG1360	Flagellar Motor Protein
KXJ75_07035	COG1192	Involved in chromosome partitioning
KXJ75_07045	COG0835	chemotaxis
KXJ75_07060	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
KXJ75_07065	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
KXJ75_07070	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
KXJ75_07075	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
KXJ75_07085	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KXJ75_07095	COG0457	Tetratricopeptide repeat
KXJ75_07110	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
KXJ75_07115	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
KXJ75_07115	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
KXJ75_07130	COG0259	pyridoxamine-phosphate oxidase activity
KXJ75_07140	COG3153	acetyltransferase
KXJ75_07155	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
KXJ75_07210	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
KXJ75_07290	COG2974	May be involved in recombination
KXJ75_07340	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
KXJ75_07405	COG0305	Participates in initiation and elongation during chromosome replication
KXJ75_07435	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
KXJ75_07630	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
KXJ75_07635	COG1196	nuclear chromosome segregation
KXJ75_07650	COG2189	Belongs to the N(4) N(6)-methyltransferase family
KXJ75_07660	COG2003	Belongs to the UPF0758 family
KXJ75_07725	COG5377	YqaJ viral recombinase family
KXJ75_07740	COG3311	Transcriptional regulator
KXJ75_07745	COG4983	Phage plasmid primase, P4 family domain protein
KXJ75_07760	COG0582	viral genome integration into host DNA
KXJ75_07770	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
KXJ75_07775	COG2867	negative regulation of translational initiation
KXJ75_07780	COG2914	Belongs to the UPF0125 (RnfH) family
KXJ75_07790	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
KXJ75_07825	COG0564	pseudouridine synthase activity
KXJ75_07830	COG1957	nucleoside hydrolase
KXJ75_07855	COG1280	lysine exporter protein (LysE YggA)
KXJ75_07880	COG1876	peptidase activity
KXJ75_07885	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
KXJ75_07890	COG1393	Belongs to the ArsC family
KXJ75_07905	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
KXJ75_07910	COG0017	Asparaginyl-tRNA synthetase
KXJ75_07925	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
KXJ75_07930	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
KXJ75_07950	COG0501	Belongs to the peptidase M48B family
KXJ75_07955	COG3217	Mosc domain protein beta barrel domain protein
KXJ75_07955	COG3217	Mosc domain protein beta barrel domain protein
KXJ75_07955	COG0633	Ferredoxin
KXJ75_07955	COG0633	Ferredoxin
KXJ75_07965	COG0674	pyruvate-flavodoxin oxidoreductase activity
KXJ75_07965	COG1013	pyruvate-flavodoxin oxidoreductase activity
KXJ75_07965	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
KXJ75_07965	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
KXJ75_07970	COG2841	Protein conserved in bacteria
KXJ75_07980	COG0534	Mate efflux family protein
KXJ75_08015	COG1309	transcriptional regulator
KXJ75_08035	COG0583	DNA-binding transcription factor activity
KXJ75_08055	COG0500	methyltransferase
KXJ75_08060	COG4106	trans-aconitate 2-methyltransferase activity
KXJ75_08065	COG1801	Protein of unknown function DUF72
KXJ75_08070	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
KXJ75_08075	COG0217	transcriptional regulatory protein
KXJ75_08080	COG2194	sulfuric ester hydrolase activity
KXJ75_08085	COG1846	Transcriptional regulator
KXJ75_08085	COG1940	carbohydrate kinase activity
KXJ75_08090	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
KXJ75_08095	COG0363	glucosamine-6-phosphate deaminase activity
KXJ75_08100	COG2190	(PTS) system
KXJ75_08100	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KXJ75_08100	COG1263	PTS System
KXJ75_08110	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
KXJ75_08115	COG0735	belongs to the Fur family
KXJ75_08125	COG0716	FMN binding
KXJ75_08140	COG0596	Alpha beta hydrolase
KXJ75_08145	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
KXJ75_08150	COG0033	Phosphoglucomutase
KXJ75_08160	COG1846	Transcriptional regulator
KXJ75_08170	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
KXJ75_08175	COG4136	ATPase activity
KXJ75_08185	COG4134	Bacterial extracellular solute-binding protein
KXJ75_08195	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
KXJ75_08205	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
KXJ75_08220	COG2911	Protein conserved in bacteria
KXJ75_08240	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
KXJ75_08250	COG0741	lytic transglycosylase activity
KXJ75_08265	COG1607	acyl-coa hydrolase
KXJ75_08275	COG3021	interspecies interaction between organisms
KXJ75_08285	COG1388	LysM domain
KXJ75_08285	COG0741	lytic transglycosylase activity
KXJ75_08290	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KXJ75_08295	COG2226	methyltransferase
KXJ75_08300	COG0328	RNA-DNA hybrid ribonuclease activity
KXJ75_08305	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
KXJ75_08315	COG0784	Response regulator, receiver
KXJ75_08315	COG3437	response regulator, receiver
KXJ75_08320	COG1960	acyl-CoA dehydrogenase activity
KXJ75_08325	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
KXJ75_08330	COG0121	glutamine amidotransferase
KXJ75_08365	COG2197	response regulator
KXJ75_08370	COG3850	Histidine kinase
KXJ75_08375	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
KXJ75_08380	COG1149	4fe-4S ferredoxin, iron-sulfur binding domain protein
KXJ75_08380	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
KXJ75_08390	COG0243	molybdopterin cofactor binding
KXJ75_08395	COG0437	4 iron, 4 sulfur cluster binding
KXJ75_08400	COG0348	domain, Protein
KXJ75_08410	COG3005	denitrification pathway
KXJ75_08415	COG0521	Mo-molybdopterin cofactor biosynthetic process
KXJ75_08420	COG0315	cyclic pyranopterin monophosphate synthase activity
KXJ75_08425	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
KXJ75_08435	COG0314	molybdopterin synthase activity
KXJ75_08450	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
KXJ75_08455	COG2267	carboxylic ester hydrolase activity
KXJ75_08460	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
KXJ75_08470	COG0302	gtp cyclohydrolase
KXJ75_08480	COG2759	Belongs to the formate--tetrahydrofolate ligase family
KXJ75_08490	COG0583	DNA-binding transcription factor activity
KXJ75_08525	COG1166	arginine decarboxylase activity
KXJ75_08565	COG1484	DNA-dependent DNA replication
KXJ75_08600	COG5433	transposase activity
KXJ75_08650	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
KXJ75_08655	COG1187	pseudouridine synthase activity
KXJ75_08660	COG2807	transmembrane transport
KXJ75_08670	COG0583	DNA-binding transcription factor activity
KXJ75_08700	COG2979	Protein of unknown function (DUF533)
KXJ75_08715	COG1595	DNA-templated transcription, initiation
KXJ75_08740	COG1294	oxidase, subunit
KXJ75_08750	COG2814	Major facilitator Superfamily
KXJ75_08755	COG0656	L-ascorbic acid biosynthetic process
KXJ75_08775	COG0583	DNA-binding transcription factor activity
KXJ75_08780	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
KXJ75_08785	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
KXJ75_08790	COG2271	Major facilitator Superfamily
KXJ75_08795	COG1349	DNA-binding transcription factor activity
KXJ75_08805	COG0584	glycerophosphoryl diester phosphodiesterase
KXJ75_08810	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
KXJ75_08825	COG3085	chromosome segregation
KXJ75_08830	COG4574	serine-type endopeptidase inhibitor activity
KXJ75_08840	COG3335	DDE superfamily endonuclease
KXJ75_08845	COG3083	sulfuric ester hydrolase activity
KXJ75_08850	COG3082	Protein of unknown function (DUF1414)
KXJ75_08855	COG3081	Nucleoid-associated protein
KXJ75_08860	COG2182	Extracellular solute-binding protein
KXJ75_08865	COG1175	transmembrane transport
KXJ75_08870	COG3833	ABC-type maltose transport systems, permease component
KXJ75_08875	COG3842	ATPase activity
KXJ75_08900	COG0425	Belongs to the sulfur carrier protein TusA family
KXJ75_08915	COG1393	Belongs to the ArsC family
KXJ75_08925	COG1228	amidohydrolase
KXJ75_08935	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KXJ75_08945	COG2431	L-lysine efflux transmembrane transporter activity
KXJ75_08955	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KXJ75_08960	COG4215	(ABC) transporter
KXJ75_08975	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
KXJ75_08985	COG0446	pyridine nucleotide-disulphide oxidoreductase
KXJ75_09030	COG2373	Large extracellular alpha-helical protein
KXJ75_09035	COG4953	penicillin-binding protein 1C
KXJ75_09045	COG0301	tRNA thio-modification
KXJ75_09045	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KXJ75_09060	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
KXJ75_09065	COG1334	flagellar protein FlaG
KXJ75_09100	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
KXJ75_09110	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
KXJ75_09125	COG0346	lactoylglutathione lyase activity
KXJ75_09130	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
KXJ75_09140	COG4659	FMN binding
KXJ75_09155	COG2878	Part of a membrane complex involved in electron transport
KXJ75_09160	COG4657	Part of a membrane complex involved in electron transport
KXJ75_09165	COG0697	spore germination
KXJ75_09195	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
KXJ75_09200	COG1288	antiporter activity
KXJ75_09205	COG0436	Aminotransferase
KXJ75_09215	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
KXJ75_09220	COG2027	D-alanyl-D-alanine carboxypeptidase
KXJ75_09230	COG1566	PFAM secretion protein HlyD family protein
KXJ75_09245	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
KXJ75_09245	COG3264	Mechanosensitive ion channel
KXJ75_09250	COG1966	Carbon starvation protein
KXJ75_09255	COG3279	Response regulator of the LytR AlgR family
KXJ75_09260	COG3275	phosphorelay sensor kinase activity
KXJ75_09270	COG1012	belongs to the aldehyde dehydrogenase family
KXJ75_09270	COG1454	alcohol dehydrogenase
KXJ75_09300	COG0601	transmembrane transport
KXJ75_09305	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KXJ75_09320	COG0861	Integral membrane protein TerC family
KXJ75_09325	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
KXJ75_09335	COG1301	dicarboxylic acid transport
KXJ75_09350	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
KXJ75_09365	COG0537	adenosine 5'-monophosphoramidase activity
KXJ75_09400	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
KXJ75_09405	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
KXJ75_09420	COG2354	Protein conserved in bacteria
KXJ75_09435	COG3150	esterase
KXJ75_09440	COG1252	NADH dehydrogenase
KXJ75_09445	COG0393	Putative heavy-metal-binding
KXJ75_09450	COG1619	proteins homologs of microcin C7 resistance protein MccF
KXJ75_09455	COG1368	sulfuric ester hydrolase activity
KXJ75_09465	COG0527	aspartate kinase activity
KXJ75_09470	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
KXJ75_09470	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
KXJ75_09475	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
KXJ75_09500	COG0583	DNA-binding transcription factor activity
KXJ75_09505	COG1620	l-lactate permease
KXJ75_09510	COG0247	lactate metabolic process
KXJ75_09515	COG1139	Iron-sulfur cluster binding protein
KXJ75_09550	COG1136	(ABC) transporter
KXJ75_09570	COG2814	Major facilitator Superfamily
KXJ75_09640	COG2308	Evidence 4 Homologs of previously reported genes of
KXJ75_09655	COG0659	secondary active sulfate transmembrane transporter activity
KXJ75_09700	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
KXJ75_09705	COG0326	Molecular chaperone. Has ATPase activity
KXJ75_09710	COG0563	adenylate kinase activity
KXJ75_09715	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
KXJ75_09720	COG3788	relative of glutathione S-transferase, MAPEG superfamily
KXJ75_09725	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KXJ75_09745	COG3300	MHYT domain
KXJ75_09745	COG5001	Diguanylate cyclase
KXJ75_09750	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
KXJ75_09775	COG1021	2,3-dihydroxybenzoate-AMP ligase
KXJ75_09780	COG1535	isochorismatase
KXJ75_09780	COG3433	isochorismatase activity
KXJ75_09790	COG1028	Short-chain dehydrogenase reductase Sdr
KXJ75_09800	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KXJ75_09805	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
KXJ75_09810	COG2977	Belongs to the P-Pant transferase superfamily
KXJ75_09815	COG1120	ATPase activity
KXJ75_09820	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KXJ75_09825	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KXJ75_09870	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
KXJ75_09875	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
KXJ75_09885	COG0861	Integral membrane protein TerC family
KXJ75_09900	COG1022	Amp-dependent synthetase and ligase
KXJ75_09905	COG0295	cytidine deaminase activity
KXJ75_09910	COG1346	cytolysis
KXJ75_09915	COG1380	Effector of murein hydrolase LrgA
KXJ75_09920	COG3345	alpha-galactosidase
KXJ75_09930	COG2925	Exonuclease
KXJ75_09960	COG5433	transposase activity
KXJ75_10005	COG3335	DDE superfamily endonuclease
KXJ75_10010	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
KXJ75_10020	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
KXJ75_10025	COG0436	Aminotransferase
KXJ75_10030	COG0583	DNA-binding transcription factor activity
KXJ75_10035	COG2160	L-arabinose isomerase activity
KXJ75_10045	COG1069	ribulokinase activity
KXJ75_10050	COG1879	ABC-type sugar transport system periplasmic component
KXJ75_10055	COG1129	ABC transporter
KXJ75_10060	COG1172	Belongs to the binding-protein-dependent transport system permease family
KXJ75_10070	COG0257	Belongs to the bacterial ribosomal protein bL36 family
KXJ75_10075	COG0254	rRNA binding
KXJ75_10090	COG1451	nucleotide metabolic process
KXJ75_10105	COG3069	C4-dicarboxylate transmembrane transporter activity
KXJ75_10155	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
KXJ75_10175	COG2009	succinate dehydrogenase
KXJ75_10180	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
KXJ75_10185	COG1053	succinate dehydrogenase
KXJ75_10195	COG0567	Dehydrogenase, E1 component
KXJ75_10200	COG0508	dehydrogenase complex catalyzes the overall conversion of
KXJ75_10205	COG0045	succinate-CoA ligase (ADP-forming) activity
KXJ75_10210	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
KXJ75_10220	COG2983	Belongs to the UPF0260 family
KXJ75_10225	COG1882	Formate acetyltransferase
KXJ75_10230	COG2116	formate transmembrane transporter activity
KXJ75_10235	COG1944	ATP diphosphatase activity
KXJ75_10245	COG2076	Multidrug Resistance protein
KXJ75_10250	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
KXJ75_10255	COG1278	Cold shock
KXJ75_10260	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
KXJ75_10265	COG0542	response to heat
KXJ75_10270	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
KXJ75_10275	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
KXJ75_10280	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
KXJ75_10285	COG3134	Outer membrane lipoprotein
KXJ75_10290	COG3706	GGDEF domain
KXJ75_10295	COG0492	ferredoxin-NADP+ reductase activity
KXJ75_10300	COG0686	Belongs to the AlaDH PNT family
KXJ75_10310	COG0531	amino acid
KXJ75_10310	COG1674	ftsk spoiiie
KXJ75_10315	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
KXJ75_10325	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
KXJ75_10330	COG1286	toxin biosynthetic process
KXJ75_10335	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
KXJ75_10345	COG1263	PTS System
KXJ75_10345	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KXJ75_10370	COG4172	Belongs to the ABC transporter superfamily
KXJ75_10380	COG4171	peptide transport system, permease
KXJ75_10385	COG4168	peptide transport system, permease
KXJ75_10400	COG1842	Phage shock protein A
KXJ75_10420	COG3768	UPF0283 membrane protein
KXJ75_10430	COG2154	pterin-4-alpha-carbinolamine dehydratase
KXJ75_10450	COG2885	chlorophyll binding
KXJ75_10470	COG1570	exodeoxyribonuclease VII activity
KXJ75_10495	COG1874	Beta-galactosidase
KXJ75_10495	COG0366	Alpha amylase catalytic
KXJ75_10515	COG0517	IMP dehydrogenase activity
KXJ75_10515	COG0516	GMP reductase activity
KXJ75_10520	COG0519	Catalyzes the synthesis of GMP from XMP
KXJ75_10520	COG0518	GMP synthase (glutamine-hydrolyzing) activity
KXJ75_10525	COG0582	viral genome integration into host DNA
KXJ75_10550	COG0653	protein targeting
KXJ75_10615	COG0210	DNA helicase
KXJ75_10720	COG2062	phosphohistidine phosphatase, SixA
KXJ75_10730	COG0697	spore germination
KXJ75_10735	COG4166	transmembrane transport
KXJ75_10740	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
KXJ75_10765	COG1136	(ABC) transporter
KXJ75_10775	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
KXJ75_10785	COG0544	peptidyl-prolyl cis-trans isomerase activity
KXJ75_10790	COG0740	serine-type endopeptidase activity
KXJ75_10795	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
KXJ75_10800	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
KXJ75_10805	COG0776	regulation of translation
KXJ75_10810	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
KXJ75_10815	COG0488	(ABC) transporter
KXJ75_10820	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KXJ75_10840	COG1024	Enoyl-CoA hydratase
KXJ75_10845	COG1115	amino acid carrier protein
KXJ75_10855	COG3228	Belongs to the MtfA family
KXJ75_10860	COG1584	GPR1 FUN34 yaaH family protein
KXJ75_10895	COG1960	acyl-CoA dehydrogenase activity
KXJ75_10910	COG1024	Enoyl-CoA hydratase
KXJ75_10915	COG1024	Enoyl-CoA hydratase
KXJ75_10940	COG0730	response to heat
KXJ75_10960	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
KXJ75_10990	COG2003	Belongs to the UPF0758 family
KXJ75_11125	COG1464	Belongs to the NlpA lipoprotein family
KXJ75_11175	COG0243	molybdopterin cofactor binding
KXJ75_11200	COG2723	6-phospho-beta-galactosidase activity
KXJ75_11210	COG0583	DNA-binding transcription factor activity
KXJ75_11230	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
KXJ75_11260	COG1560	Kdo2-lipid A biosynthetic process
KXJ75_11280	COG0417	DNA replication proofreading
KXJ75_11310	COG0534	Mate efflux family protein
KXJ75_11320	COG0307	riboflavin synthase, alpha
KXJ75_11335	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
KXJ75_11340	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
KXJ75_11345	COG0697	spore germination
KXJ75_11350	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
KXJ75_11390	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
KXJ75_11395	COG3099	Belongs to the UPF0263 family
KXJ75_11400	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
KXJ75_11405	COG2894	cell division
KXJ75_11410	COG0850	regulation of cytokinetic process
KXJ75_11415	COG3100	YcgL domain-containing protein
KXJ75_11420	COG2951	lytic endotransglycosylase activity
KXJ75_11430	COG1760	l-serine dehydratase
KXJ75_11435	COG1760	l-serine dehydratase
KXJ75_11440	COG3123	guanosine phosphorylase activity
KXJ75_11460	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
KXJ75_11465	COG2067	long-chain fatty acid transport protein
KXJ75_11470	COG2067	long-chain fatty acid transport protein
KXJ75_11480	COG1595	DNA-templated transcription, initiation
KXJ75_11510	COG0714	Associated with various cellular activities
KXJ75_11515	COG0183	Belongs to the thiolase family
KXJ75_11520	COG1024	Enoyl-CoA hydratase
KXJ75_11520	COG1250	3-hydroxyacyl-CoA dehydrogenase
KXJ75_11530	COG4681	YaeQ
KXJ75_11575	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
KXJ75_11585	COG1538	Outer membrane efflux protein
KXJ75_11610	COG3134	Outer membrane lipoprotein
KXJ75_11625	COG0107	imidazoleglycerol-phosphate synthase activity
KXJ75_11630	COG0784	Response regulator, receiver
KXJ75_11630	COG2198	Histidine kinase
KXJ75_11630	COG2205	protein histidine kinase activity
KXJ75_11635	COG2199	diguanylate cyclase activity
KXJ75_11640	COG3437	response regulator, receiver
KXJ75_11645	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
KXJ75_11650	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
KXJ75_11655	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
KXJ75_11655	COG0131	Imidazoleglycerol-phosphate dehydratase
KXJ75_11660	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
KXJ75_11665	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
KXJ75_11685	COG1214	PFAM Peptidase M22, glycoprotease
KXJ75_11695	COG2267	carboxylic ester hydrolase activity
KXJ75_11700	COG0318	PFAM AMP-dependent synthetase and ligase
KXJ75_11720	COG2197	response regulator
KXJ75_11730	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
KXJ75_11740	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
KXJ75_11750	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
KXJ75_11755	COG1335	isochorismatase
KXJ75_11795	COG2197	response regulator
KXJ75_11800	COG0517	IMP dehydrogenase activity
KXJ75_11800	COG0617	tRNA 3'-terminal CCA addition
KXJ75_11800	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
KXJ75_11805	COG1643	Atp-dependent helicase
KXJ75_11815	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
KXJ75_11825	COG3437	response regulator, receiver
KXJ75_11835	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
KXJ75_11840	COG0709	Synthesizes selenophosphate from selenide and ATP
KXJ75_11845	COG0435	Glutathione S-transferase
KXJ75_11850	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
KXJ75_11860	COG1254	Belongs to the acylphosphatase family
KXJ75_11870	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KXJ75_11870	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KXJ75_11875	COG0489	protein tyrosine kinase activity
KXJ75_11880	COG0572	uridine kinase
KXJ75_11885	COG0717	Belongs to the dCTP deaminase family
KXJ75_11900	COG1530	ribonuclease E activity
KXJ75_11920	COG1399	metal-binding, possibly nucleic acid-binding protein
KXJ75_11925	COG0333	Belongs to the bacterial ribosomal protein bL32 family
KXJ75_11930	COG0416	fatty acid biosynthetic process
KXJ75_11935	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KXJ75_11945	COG1028	Short-chain dehydrogenase reductase Sdr
KXJ75_11950	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
KXJ75_11960	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
KXJ75_11965	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
KXJ75_11970	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
KXJ75_11975	COG0470	DNA polymerase III
KXJ75_11980	COG0084	hydrolase, TatD family'
KXJ75_12000	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
KXJ75_12000	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
KXJ75_12010	COG2995	paraquat-inducible protein a
KXJ75_12020	COG3141	response to X-ray
KXJ75_12060	COG1484	DNA-dependent DNA replication
KXJ75_12105	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
KXJ75_12115	COG0642	Histidine kinase
KXJ75_12120	COG2207	Transcriptional regulator
KXJ75_12120	COG4753	response regulator
KXJ75_12150	COG3039	Transposase
KXJ75_12175	COG5433	transposase activity
KXJ75_12180	COG1067	ATP-dependent peptidase activity
KXJ75_12185	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
KXJ75_12200	COG0488	(ABC) transporter
KXJ75_12210	COG0116	Belongs to the methyltransferase superfamily
KXJ75_12210	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
KXJ75_12220	COG0167	dihydroorotate dehydrogenase activity
KXJ75_12260	COG0308	aminopeptidase N
KXJ75_12270	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
KXJ75_12275	COG1956	GAF domain-containing protein
KXJ75_12290	COG3278	Belongs to the heme-copper respiratory oxidase family
KXJ75_12305	COG2010	Cytochrome c
KXJ75_12330	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
KXJ75_12335	COG0589	response to stress
KXJ75_12340	COG0037	tRNA processing
KXJ75_12355	COG0675	Transposase, IS605 OrfB family
KXJ75_12360	COG0675	Transposase, IS605 OrfB family
KXJ75_12375	COG0625	glutathione transferase activity
KXJ75_12380	COG1869	D-ribose catabolic process
KXJ75_12385	COG1129	ABC transporter
KXJ75_12390	COG1172	Belongs to the binding-protein-dependent transport system permease family
KXJ75_12395	COG1879	ABC-type sugar transport system periplasmic component
KXJ75_12400	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KXJ75_12405	COG1609	Transcriptional regulator
KXJ75_12440	COG0776	regulation of translation
KXJ75_12445	COG0072	phenylalanine-tRNA ligase activity
KXJ75_12445	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KXJ75_12450	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
KXJ75_12455	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
KXJ75_12460	COG0291	Belongs to the bacterial ribosomal protein bL35 family
KXJ75_12465	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
KXJ75_12470	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
KXJ75_12500	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
KXJ75_12515	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KXJ75_12520	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KXJ75_12525	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
KXJ75_12530	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
KXJ75_12535	COG3313	Fe-S protein
KXJ75_12540	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
KXJ75_12540	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
KXJ75_12540	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
KXJ75_12545	COG1105	Belongs to the carbohydrate kinase PfkB family
KXJ75_12550	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
KXJ75_12550	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
KXJ75_12555	COG1609	Transcriptional regulator
KXJ75_12560	COG0814	amino acid
KXJ75_12570	COG5654	RES domain protein
KXJ75_12575	COG0513	Belongs to the DEAD box helicase family
KXJ75_12585	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
KXJ75_12590	COG2890	protein-(glutamine-N5) methyltransferase activity
KXJ75_12630	COG2824	Alkylphosphonate utilization operon protein PhnA
KXJ75_12645	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
KXJ75_12650	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
KXJ75_12670	COG1484	DNA-dependent DNA replication
KXJ75_12700	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
KXJ75_12705	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
KXJ75_12715	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
KXJ75_12720	COG1434	Gram-negative-bacterium-type cell wall biogenesis
KXJ75_12730	COG0205	6-phosphofructokinase activity
KXJ75_12735	COG1473	amidohydrolase
KXJ75_12740	COG1011	Hydrolase
KXJ75_12810	COG0583	DNA-binding transcription factor activity
KXJ75_12815	COG0730	response to heat
KXJ75_12830	COG3148	PFAM DTW domain containing protein
KXJ75_12835	COG1181	Belongs to the D-alanine--D-alanine ligase family
KXJ75_12850	COG0513	Belongs to the DEAD box helicase family
KXJ75_12890	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
KXJ75_12915	COG0675	Transposase, IS605 OrfB family
KXJ75_12940	COG2501	S4 domain
KXJ75_12960	COG1132	(ABC) transporter
KXJ75_12975	COG3118	belongs to the thioredoxin family
KXJ75_12980	COG0471	metal ion transport
KXJ75_12990	COG0058	SHG alpha-glucan phosphorylase activity
KXJ75_13020	COG0814	amino acid
KXJ75_13025	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
KXJ75_13030	COG0514	ATP-dependent DNA helicase (RecQ)
KXJ75_13035	COG2766	serine protein kinase
KXJ75_13040	COG2718	Belongs to the UPF0229 family
KXJ75_13045	COG2719	SpoVR family
KXJ75_13055	COG2186	Transcriptional regulator
KXJ75_13060	COG3067	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
KXJ75_13065	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
KXJ75_13070	COG0586	Pfam SNARE associated Golgi protein
KXJ75_13090	COG2985	domain, Protein
KXJ75_13090	COG0569	domain protein
KXJ75_13100	COG1940	carbohydrate kinase activity
KXJ75_13100	COG1846	Transcriptional regulator
KXJ75_13110	COG3012	SEC-C Motif Domain Protein
KXJ75_13120	COG3075	Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses fumarate or nitrate as electron acceptor
KXJ75_13125	COG0247	lactate metabolic process
KXJ75_13160	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
KXJ75_13165	COG0437	4 iron, 4 sulfur cluster binding
KXJ75_13170	COG3301	Polysulphide reductase, NrfD
KXJ75_13175	COG1138	Cytochrome C-type biogenesis protein
KXJ75_13200	COG3046	protein related to deoxyribodipyrimidine photolyase
KXJ75_13205	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KXJ75_13220	COG0517	IMP dehydrogenase activity
KXJ75_13225	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
KXJ75_13230	COG0583	DNA-binding transcription factor activity
KXJ75_13245	COG1917	Cupin 2, conserved barrel domain protein
KXJ75_13245	COG4977	sequence-specific DNA binding
KXJ75_13255	COG0583	DNA-binding transcription factor activity
KXJ75_13260	COG2910	NAD(P)H-binding
KXJ75_13275	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
KXJ75_13305	COG2226	methyltransferase
KXJ75_13365	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
KXJ75_13370	COG0830	nickel cation binding
KXJ75_13390	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
KXJ75_13395	COG0804	urea catabolic process
KXJ75_13400	COG0832	Belongs to the urease beta subunit family
KXJ75_13405	COG0831	urea catabolic process
KXJ75_13410	COG0829	nickel cation binding
KXJ75_13420	COG0411	ABC transporter
KXJ75_13445	COG2205	protein histidine kinase activity
KXJ75_13445	COG2198	Histidine kinase
KXJ75_13445	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KXJ75_13445	COG0784	Response regulator, receiver
KXJ75_13450	COG0745	RESPONSE REGULATOR receiver
KXJ75_13460	COG1484	DNA-dependent DNA replication
KXJ75_13465	COG4584	PFAM Integrase catalytic
KXJ75_13585	COG3550	peptidyl-serine autophosphorylation
KXJ75_13665	COG1435	thymidine kinase activity
KXJ75_13670	COG1757	Na H antiporter
KXJ75_13680	COG2916	Histone family protein nucleoid-structuring protein H-NS
KXJ75_13685	COG2096	Adenosyltransferase
KXJ75_13690	COG3530	Putative quorum-sensing-regulated virulence factor
KXJ75_13695	COG0602	queuosine metabolic process
KXJ75_13720	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
KXJ75_13730	COG0776	regulation of translation
KXJ75_13735	COG0539	negative regulation of cytoplasmic translation
KXJ75_13740	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
KXJ75_13745	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
KXJ75_13750	COG0583	DNA-binding transcription factor activity
KXJ75_13770	COG0778	Nitroreductase
KXJ75_13775	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
KXJ75_13790	COG0583	DNA-binding transcription factor activity
KXJ75_13820	COG4989	oxidoreductase activity
KXJ75_13825	COG0724	RNA recognition motif
KXJ75_13835	COG3770	Murein endopeptidase that cleaves the D-alanyl-meso-2,6- diamino-pimelyl amide bond that connects peptidoglycan strands. Likely plays a role in the removal of murein from the sacculus
KXJ75_13845	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
KXJ75_13860	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
KXJ75_13865	COG1360	Flagellar Motor Protein
KXJ75_13875	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
KXJ75_13880	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
KXJ75_13885	COG0649	NAD binding
KXJ75_13885	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
KXJ75_13900	COG1034	ATP synthesis coupled electron transport
KXJ75_13905	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
KXJ75_13910	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
KXJ75_13915	COG0839	Belongs to the complex I subunit 6 family
KXJ75_13920	COG0713	ATP synthesis coupled electron transport
KXJ75_13930	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
KXJ75_13935	COG1007	ATP synthesis coupled electron transport
KXJ75_13940	COG0047	phosphoribosylformylglycinamidine synthase activity
KXJ75_13940	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
KXJ75_13945	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
KXJ75_13950	COG1645	bacterial-type flagellum-dependent swarming motility
KXJ75_13955	COG1160	GTP binding
KXJ75_13960	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
KXJ75_13965	COG2976	Protein conserved in bacteria
KXJ75_13970	COG0124	histidyl-tRNA synthetase
KXJ75_13990	COG0820	rRNA (adenine-C2-)-methyltransferase activity
KXJ75_13995	COG0105	UTP biosynthetic process
KXJ75_14015	COG0633	Ferredoxin
KXJ75_14020	COG0443	Heat shock 70 kDa protein
KXJ75_14025	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
KXJ75_14035	COG0822	iron-sulfur transferase activity
KXJ75_14040	COG1104	cysteine desulfurase activity
KXJ75_14060	COG3154	lipid carrier protein
KXJ75_14065	COG0826	peptidase U32
KXJ75_14070	COG0826	peptidase U32
KXJ75_14085	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
KXJ75_14090	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
KXJ75_14095	COG1862	Preprotein translocase
KXJ75_14100	COG0343	queuine tRNA-ribosyltransferase activity
KXJ75_14110	COG0517	IMP dehydrogenase activity
KXJ75_14125	COG3634	alkyl hydroperoxide reductase activity
KXJ75_14160	COG3039	Transposase
KXJ75_14195	COG5642	Protein of unknown function (DUF2384)
KXJ75_14200	COG4584	PFAM Integrase catalytic
KXJ75_14250	COG5433	transposase activity
KXJ75_14275	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
KXJ75_14275	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
KXJ75_14280	COG0509	glycine decarboxylation via glycine cleavage system
KXJ75_14285	COG0404	The glycine cleavage system catalyzes the degradation of glycine
KXJ75_14290	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
KXJ75_14300	COG3079	Belongs to the UPF0149 family
KXJ75_14315	COG2814	Major facilitator Superfamily
KXJ75_14320	COG0625	glutathione transferase activity
KXJ75_14335	COG0483	inositol monophosphate 1-phosphatase activity
KXJ75_14355	COG2056	Na+-H+ antiporter family
KXJ75_14360	COG2814	Major facilitator Superfamily
KXJ75_14365	COG0583	DNA-binding transcription factor activity
KXJ75_14375	COG2050	protein possibly involved in aromatic compounds catabolism
KXJ75_14395	COG1253	flavin adenine dinucleotide binding
KXJ75_14420	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
KXJ75_14425	COG0647	UMP catabolic process
KXJ75_14435	COG0367	asparagine synthase
KXJ75_14450	COG0625	glutathione transferase activity
KXJ75_14475	COG0564	pseudouridine synthase activity
KXJ75_14480	COG5001	Diguanylate cyclase
KXJ75_14490	COG0318	PFAM AMP-dependent synthetase and ligase
KXJ75_14495	COG0318	PFAM AMP-dependent synthetase and ligase
KXJ75_14540	COG2855	membrane
KXJ75_14565	COG3246	L-lysine catabolic process to acetate
KXJ75_14570	COG2175	clavaminate synthase activity
KXJ75_14580	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
KXJ75_14605	COG0670	Belongs to the BI1 family
KXJ75_14615	COG1289	transmembrane transporter activity
KXJ75_14620	COG2920	part of a sulfur-relay system
KXJ75_14625	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
KXJ75_14630	COG0285	dihydrofolate synthase activity
KXJ75_14635	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
KXJ75_14640	COG0101	tRNA pseudouridine synthase activity
KXJ75_14650	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
KXJ75_14655	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
KXJ75_14660	COG0671	phosphoesterase, PA-phosphatase related
KXJ75_14665	COG1464	Belongs to the NlpA lipoprotein family
KXJ75_14685	COG1119	ATPase activity
KXJ75_14690	COG0574	Belongs to the PEP-utilizing enzyme family
KXJ75_14690	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
KXJ75_14695	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
KXJ75_14710	COG1113	amino acid transport
KXJ75_14755	COG1242	4 iron, 4 sulfur cluster binding
KXJ75_14765	COG0493	'glutamate synthase
KXJ75_14770	COG1126	abc transporter atp-binding protein
KXJ75_14775	COG0765	amino acid transport
KXJ75_14780	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KXJ75_14790	COG0789	Transcriptional regulator
KXJ75_14815	COG0513	Belongs to the DEAD box helicase family
KXJ75_14855	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
KXJ75_14860	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
KXJ75_14870	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
KXJ75_14880	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
KXJ75_14885	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
KXJ75_14890	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
KXJ75_14895	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
KXJ75_14900	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
KXJ75_14905	COG4138	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system
KXJ75_14940	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
KXJ75_14950	COG0023	Translation Initiation Factor
KXJ75_14955	COG2119	membrane
KXJ75_14990	COG2199	diguanylate cyclase activity
KXJ75_14990	COG2203	Gaf domain
KXJ75_15040	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
KXJ75_15050	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
KXJ75_15055	COG2261	transglycosylase associated protein
KXJ75_15060	COG1309	transcriptional regulator
KXJ75_15080	COG0248	Ppx GppA phosphatase
KXJ75_15190	COG2197	response regulator
KXJ75_15195	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
KXJ75_15200	COG2835	tetraacyldisaccharide 4'-kinase activity
KXJ75_15210	COG1132	(ABC) transporter
KXJ75_15230	COG0433	COG0433 Predicted ATPase
KXJ75_15235	COG1448	Aminotransferase
KXJ75_15255	COG5433	transposase activity
KXJ75_15310	COG4974	Belongs to the 'phage' integrase family
KXJ75_15330	COG1199	ATP-dependent helicase activity
KXJ75_15350	COG0123	including yeast histone deacetylase and acetoin utilization protein
KXJ75_15355	COG0477	Major facilitator Superfamily
KXJ75_15360	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
KXJ75_15365	COG1785	Belongs to the alkaline phosphatase family
KXJ75_15385	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
KXJ75_15395	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KXJ75_15400	COG0765	amino acid transport
KXJ75_15425	COG0531	amino acid
KXJ75_15440	COG1253	flavin adenine dinucleotide binding
KXJ75_15445	COG0704	Plays a role in the regulation of phosphate uptake
KXJ75_15450	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
KXJ75_15455	COG0581	inorganic phosphate transmembrane transporter activity
KXJ75_15460	COG0573	inorganic phosphate transmembrane transporter activity
KXJ75_15465	COG0590	tRNA wobble adenosine to inosine editing
KXJ75_15480	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
KXJ75_15500	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
KXJ75_15505	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
KXJ75_15510	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
KXJ75_15515	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
KXJ75_15540	COG2716	regulation of RNA biosynthetic process
KXJ75_15545	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
KXJ75_15560	COG0675	Transposase, IS605 OrfB family
KXJ75_15570	COG0675	Transposase, IS605 OrfB family
KXJ75_15610	COG3951	Flagellar rod assembly protein muramidase FlgJ
KXJ75_15610	COG1705	Flagellar rod assembly protein muramidase FlgJ
KXJ75_15615	COG1706	bacterial-type flagellum-dependent cell motility
KXJ75_15620	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
KXJ75_15635	COG1749	Flagellar hook protein flgE
KXJ75_15650	COG1815	bacterial-type flagellum-dependent cell motility
KXJ75_15655	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
KXJ75_15660	COG0784	Response regulator, receiver
KXJ75_15660	COG0835	chemotaxis
KXJ75_15665	COG1261	Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly
KXJ75_15680	COG0622	Phosphoesterase
KXJ75_15710	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
KXJ75_15715	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
KXJ75_15720	COG1882	Formate acetyltransferase
KXJ75_15725	COG1349	DNA-binding transcription factor activity
KXJ75_15730	COG0697	spore germination
KXJ75_15760	COG1278	Cold shock
KXJ75_15805	COG3132	Protein of unknown function, DUF480
KXJ75_15845	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
KXJ75_15855	COG1091	dTDP-4-dehydrorhamnose reductase activity
KXJ75_15860	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
KXJ75_15870	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
KXJ75_15870	COG0662	Cupin 2, conserved barrel domain protein
KXJ75_15885	COG1216	Glycosyl transferase, family 2
KXJ75_15935	COG1091	dTDP-4-dehydrorhamnose reductase activity
KXJ75_15955	COG1482	cell wall glycoprotein biosynthetic process
KXJ75_15970	COG1737	Transcriptional regulator
KXJ75_15975	COG0469	pyruvate kinase activity
KXJ75_15985	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
KXJ75_16000	COG0675	Transposase, IS605 OrfB family
KXJ75_16005	COG1960	acyl-CoA dehydrogenase activity
KXJ75_16015	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
KXJ75_16035	COG0583	DNA-binding transcription factor activity
KXJ75_16050	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
KXJ75_16055	COG1484	DNA-dependent DNA replication
KXJ75_16075	COG2003	Belongs to the UPF0758 family
KXJ75_16135	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KXJ75_16150	COG5433	transposase activity
KXJ75_16160	COG3385	transposase activity
KXJ75_16165	COG1946	Acyl-CoA thioesterase
KXJ75_16180	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
KXJ75_16190	COG0009	L-threonylcarbamoyladenylate synthase
KXJ75_16200	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
KXJ75_16205	COG0512	Glutamine amidotransferase of anthranilate synthase
KXJ75_16205	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
KXJ75_16210	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
KXJ75_16215	COG0134	indole-3-glycerol-phosphate synthase activity
KXJ75_16215	COG0135	phosphoribosylanthranilate isomerase activity
KXJ75_16220	COG0133	tryptophan synthase activity
KXJ75_16225	COG0159	tryptophan synthase activity
KXJ75_16245	COG1396	sequence-specific DNA binding
KXJ75_16250	COG3550	peptidyl-serine autophosphorylation
KXJ75_16270	COG0583	DNA-binding transcription factor activity
KXJ75_16285	COG5507	3-demethylubiquinone-9 3-methyltransferase
KXJ75_16300	COG0109	protoheme IX farnesyltransferase activity
KXJ75_16305	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
KXJ75_16310	COG1845	cytochrome c oxidase, subunit III
KXJ75_16315	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
KXJ75_16320	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
KXJ75_16325	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
KXJ75_16360	COG3241	Transfers electrons from cytochrome c551 to cytochrome oxidase
KXJ75_16370	COG0071	Belongs to the small heat shock protein (HSP20) family
KXJ75_16375	COG0745	RESPONSE REGULATOR receiver
KXJ75_16385	COG0708	Exodeoxyribonuclease III
KXJ75_16395	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KXJ75_16415	COG0095	Lipoate-protein ligase
KXJ75_16425	COG0577	efflux transmembrane transporter activity
KXJ75_16425	COG1136	(ABC) transporter
KXJ75_16430	COG0577	efflux transmembrane transporter activity
KXJ75_16430	COG1136	(ABC) transporter
KXJ75_16435	COG1136	(ABC) transporter
KXJ75_16435	COG0577	efflux transmembrane transporter activity
KXJ75_16480	COG1285	pathogenesis
KXJ75_16510	COG0484	heat shock protein binding
KXJ75_16515	COG0443	Heat shock 70 kDa protein
KXJ75_16520	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
KXJ75_16525	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
KXJ75_16530	COG0497	DNA recombination
KXJ75_16535	COG1227	inorganic diphosphatase activity
KXJ75_16545	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KXJ75_16555	COG1538	Outer membrane efflux protein
KXJ75_16560	COG2375	cellular response to nickel ion
KXJ75_16565	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
KXJ75_16575	COG2916	Histone family protein nucleoid-structuring protein H-NS
KXJ75_16585	COG5433	transposase activity
KXJ75_16590	COG0583	DNA-binding transcription factor activity
KXJ75_16595	COG3048	D-serine ammonia-lyase activity
KXJ75_16605	COG0538	isocitrate dehydrogenase activity
KXJ75_16640	COG0456	acetyltransferase
KXJ75_16645	COG1187	pseudouridine synthase activity
KXJ75_16655	COG0482	sulfurtransferase activity
KXJ75_16660	COG2915	High frequency lysogenization protein hflD homolog
KXJ75_16665	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
KXJ75_16670	COG2850	peptidyl-arginine hydroxylation
KXJ75_16680	COG3264	Mechanosensitive ion channel
KXJ75_16680	COG1196	nuclear chromosome segregation
KXJ75_16710	COG2233	PERMEase
KXJ75_16715	COG0281	malic enzyme
KXJ75_16740	COG3039	Transposase
KXJ75_16755	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
KXJ75_16760	COG0083	homoserine kinase activity
KXJ75_16770	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
KXJ75_16775	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
KXJ75_16790	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
KXJ75_16800	COG0745	RESPONSE REGULATOR receiver
KXJ75_16815	COG4988	ABC transporter
KXJ75_16820	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
KXJ75_16850	COG1720	tRNA m6t6A37 methyltransferase activity
KXJ75_16865	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
KXJ75_16870	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
KXJ75_16875	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
KXJ75_16885	COG2190	(PTS) system
KXJ75_16905	COG2814	Major facilitator Superfamily
KXJ75_16930	COG0420	3'-5' exonuclease activity
KXJ75_16935	COG0456	acetyltransferase
KXJ75_16940	COG2974	May be involved in recombination
KXJ75_16950	COG0583	DNA-binding transcription factor activity
KXJ75_16960	COG0477	Major facilitator Superfamily
KXJ75_16975	COG1484	DNA-dependent DNA replication
KXJ75_16990	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KXJ75_16995	COG1917	Cupin 2, conserved barrel domain protein
KXJ75_16995	COG1396	sequence-specific DNA binding
KXJ75_17000	COG1012	belongs to the aldehyde dehydrogenase family
KXJ75_17015	COG0531	amino acid
KXJ75_17020	COG0531	amino acid
KXJ75_17030	COG1283	sodium-dependent phosphate transmembrane transporter activity
KXJ75_17040	COG3384	dioxygenase
KXJ75_17080	COG0784	Response regulator, receiver
KXJ75_17080	COG2205	protein histidine kinase activity
KXJ75_17110	COG1388	LysM domain
KXJ75_17110	COG1376	ErfK ybiS ycfS ynhG family protein
KXJ75_17125	COG3129	Specifically methylates the adenine in position 1618 of 23S rRNA
KXJ75_17130	COG0791	NLP P60 protein
KXJ75_17140	COG3118	belongs to the thioredoxin family
KXJ75_17150	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
KXJ75_17155	COG0788	formyltetrahydrofolate deformylase activity
KXJ75_17180	COG0739	heme binding
KXJ75_17180	COG0741	lytic transglycosylase activity
KXJ75_17180	COG1196	nuclear chromosome segregation
KXJ75_17185	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
KXJ75_17190	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
KXJ75_17195	COG0673	inositol 2-dehydrogenase activity
KXJ75_17225	COG3152	Membrane
KXJ75_17250	COG1032	radical SAM domain protein
KXJ75_17255	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
KXJ75_17270	COG1752	Esterase of the alpha-beta hydrolase superfamily
KXJ75_17275	COG0733	neurotransmitter:sodium symporter activity
KXJ75_17310	COG0281	malic enzyme
KXJ75_17325	COG0534	Mate efflux family protein
KXJ75_17340	COG2233	PERMEase
KXJ75_17345	COG0095	Lipoate-protein ligase
KXJ75_17350	COG1115	amino acid carrier protein
KXJ75_17355	COG0019	diaminopimelate decarboxylase activity
KXJ75_17370	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
KXJ75_17380	COG1126	abc transporter atp-binding protein
KXJ75_17385	COG0765	amino acid transport
KXJ75_17395	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KXJ75_17400	COG3039	Transposase
KXJ75_17415	COG1131	(ABC) transporter
KXJ75_17420	COG0545	Peptidyl-prolyl cis-trans isomerase
KXJ75_17430	COG3142	Participates in the control of copper homeostasis
KXJ75_17455	COG5002	protein histidine kinase activity
KXJ75_17460	COG0745	RESPONSE REGULATOR receiver
KXJ75_17465	COG0346	lactoylglutathione lyase activity
KXJ75_17490	COG3335	DDE superfamily endonuclease
KXJ75_17495	COG0697	spore germination
KXJ75_17505	COG3290	protein histidine kinase activity
KXJ75_17515	COG1566	PFAM secretion protein HlyD family protein
KXJ75_17550	COG0602	queuosine metabolic process
KXJ75_17555	COG1328	CTP reductase activity
KXJ75_17565	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
KXJ75_17570	COG3115	cell septum assembly
KXJ75_17575	COG1196	nuclear chromosome segregation
KXJ75_17585	COG2860	membrane
KXJ75_17595	COG3108	Peptidase M15
KXJ75_17600	COG2989	Protein conserved in bacteria
KXJ75_17615	COG0463	Glycosyl transferase, family 2
KXJ75_17630	COG0366	Alpha amylase catalytic
KXJ75_17665	COG3706	GGDEF domain
KXJ75_17675	COG3590	peptidase
KXJ75_17685	COG0488	(ABC) transporter
KXJ75_17700	COG0531	amino acid
KXJ75_17710	COG0825	malonyl-CoA metabolic process
KXJ75_17720	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
KXJ75_17725	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
KXJ75_17730	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
KXJ75_17735	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
KXJ75_17740	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
KXJ75_17755	COG0750	zinc metalloprotease
KXJ75_17760	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
KXJ75_17765	COG0575	Belongs to the CDS family
KXJ75_17770	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
KXJ75_17775	COG0233	cytoplasmic translational termination
KXJ75_17780	COG0528	UMP kinase activity
KXJ75_17785	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
KXJ75_17790	COG0052	Belongs to the universal ribosomal protein uS2 family
KXJ75_17795	COG0024	Methionine aminopeptidase
KXJ75_17800	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
KXJ75_17805	COG2171	N-acyltransferase activity
KXJ75_17820	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KXJ75_17820	COG1263	PTS System
KXJ75_17840	COG0564	pseudouridine synthase activity
KXJ75_17845	COG3098	single-species biofilm formation
KXJ75_17870	COG5595	Zn-ribbon-containing, possibly nucleic-acid-binding protein (DUF2310)
KXJ75_17880	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
KXJ75_17880	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
KXJ75_17895	COG1611	Belongs to the LOG family
KXJ75_17900	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
KXJ75_17905	COG0473	3-isopropylmalate dehydrogenase activity
KXJ75_17915	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
KXJ75_17920	COG2363	Small membrane protein
KXJ75_17930	COG0583	DNA-binding transcription factor activity
KXJ75_17935	COG0840	transmembrane signaling receptor activity
KXJ75_17940	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
KXJ75_17960	COG1477	protein flavinylation
KXJ75_17965	COG2871	sodium ion transport
KXJ75_17970	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
KXJ75_17975	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
KXJ75_17980	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
KXJ75_17985	COG1805	sodium ion transport
KXJ75_17990	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
KXJ75_18000	COG0271	Belongs to the BolA IbaG family
KXJ75_18005	COG2813	Specifically methylates the guanine in position
KXJ75_18015	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
KXJ75_18025	COG2211	Major facilitator Superfamily
KXJ75_18030	COG3248	Nucleoside-binding outer membrane protein
KXJ75_18040	COG1666	GTP binding
KXJ75_18045	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
KXJ75_18090	COG3504	Conjugal transfer protein
KXJ75_18100	COG3846	protein secretion by the type IV secretion system
KXJ75_18115	COG3451	type IV secretory pathway VirB4
KXJ75_18125	COG3838	Conjugal transfer protein Trbc
KXJ75_18130	COG4962	Type ii secretion system protein e
KXJ75_18155	COG0583	DNA-binding transcription factor activity
KXJ75_18195	COG3422	double-strand break repair
KXJ75_18220	COG4372	Transposase
KXJ75_18260	COG4959	Type IV secretory pathway protease TraF
KXJ75_18275	COG1192	Involved in chromosome partitioning
KXJ75_18305	COG5489	Protein of unknown function (DUF736)
KXJ75_18340	COG0640	Transcriptional regulator
KXJ75_18365	COG0798	PFAM Bile acid sodium symporter
KXJ75_18375	COG0431	NADPH-dependent FMN reductase
KXJ75_18380	COG2003	Belongs to the UPF0758 family
KXJ75_18385	COG4804	nuclease activity
KXJ75_18390	COG1484	DNA-dependent DNA replication
KXJ75_18395	COG4584	PFAM Integrase catalytic
KXJ75_18440	COG2771	luxR family
KXJ75_18445	COG1393	Belongs to the ArsC family
KXJ75_18450	COG0798	PFAM Bile acid sodium symporter
KXJ75_18460	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
KXJ75_18495	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
KXJ75_18505	COG1151	hydroxylamine reductase activity
KXJ75_18510	COG0783	Belongs to the Dps family
KXJ75_18535	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
KXJ75_18550	COG0300	oxidoreductase activity
KXJ75_18560	COG0415	Belongs to the DNA photolyase family
KXJ75_18565	COG0789	Transcriptional regulator
KXJ75_18570	COG3272	Protein of unknown function (DUF1722)
KXJ75_18595	COG0077	Prephenate dehydratase
KXJ75_18595	COG1605	Chorismate mutase
KXJ75_18640	COG1349	DNA-binding transcription factor activity
KXJ75_18645	COG2084	Dehydrogenase
KXJ75_18655	COG0235	Class ii aldolase
KXJ75_18660	COG3622	Belongs to the hyi family
KXJ75_18665	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
KXJ75_18670	COG2610	gluconate transmembrane transporter activity
KXJ75_18705	COG0300	oxidoreductase activity
KXJ75_18785	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
KXJ75_18795	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
KXJ75_18805	COG3813	Protein conserved in bacteria
KXJ75_18815	COG0826	peptidase U32
KXJ75_18830	COG1280	lysine exporter protein (LysE YggA)
KXJ75_18875	COG3275	phosphorelay sensor kinase activity
KXJ75_18880	COG3279	Response regulator of the LytR AlgR family
KXJ75_18915	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
KXJ75_18930	COG4263	nitrous-oxide reductase activity
KXJ75_18935	COG0348	domain, Protein
KXJ75_18935	COG3901	Regulator of nitric oxide reductase transcription
KXJ75_18940	COG0114	fumarate hydratase activity
KXJ75_18950	COG0506	proline dehydrogenase activity
KXJ75_18950	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
KXJ75_18950	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
KXJ75_18960	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
KXJ75_18980	COG0737	Belongs to the 5'-nucleotidase family
KXJ75_19020	COG2204	response regulator
KXJ75_19025	COG0545	Peptidyl-prolyl cis-trans isomerase
KXJ75_19035	COG2900	Belongs to the SlyX family
KXJ75_19040	COG1047	Peptidyl-prolyl cis-trans
KXJ75_19045	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
KXJ75_19055	COG0835	chemotaxis
KXJ75_19055	COG0784	Response regulator, receiver
KXJ75_19060	COG0429	hydrolase of the alpha beta-hydrolase fold
KXJ75_19065	COG5001	Diguanylate cyclase
KXJ75_19065	COG4251	negative regulation of phosphorylation
KXJ75_19065	COG3706	GGDEF domain
KXJ75_19065	COG2203	Gaf domain
KXJ75_19070	COG3089	Belongs to the UPF0270 family
KXJ75_19075	COG3954	Phosphoribulokinase
KXJ75_19090	COG1765	OsmC-like protein
KXJ75_19100	COG2226	methyltransferase
KXJ75_19130	COG2205	protein histidine kinase activity
KXJ75_19135	COG2814	Major facilitator Superfamily
KXJ75_19160	COG0748	coenzyme F420 binding
KXJ75_19165	COG3721	Heme iron utilization protein
KXJ75_19200	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
KXJ75_19210	COG0463	Glycosyl transferase, family 2
KXJ75_19220	COG0488	(ABC) transporter
KXJ75_19245	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
KXJ75_19250	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
KXJ75_19255	COG3178	'Phosphotransferase
KXJ75_19260	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
KXJ75_19270	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
KXJ75_19275	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
KXJ75_19280	COG2967	ApaG domain
KXJ75_19285	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
KXJ75_19295	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KXJ75_19300	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
KXJ75_19305	COG3314	Sporulation integral membrane protein YlbJ
KXJ75_19310	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
KXJ75_19315	COG0211	Belongs to the bacterial ribosomal protein bL27 family
KXJ75_19320	COG0261	This protein binds to 23S rRNA in the presence of protein L20
KXJ75_19325	COG0142	geranyltranstransferase activity
KXJ75_19345	COG0330	HflC and HflK could
KXJ75_19350	COG0330	HflC and HflK could
KXJ75_19355	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
KXJ75_19360	COG1923	regulation of RNA biosynthetic process
KXJ75_19365	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
KXJ75_19370	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
KXJ75_19380	COG0802	atpase or kinase
KXJ75_19385	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
KXJ75_19385	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
KXJ75_19410	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
KXJ75_19415	COG2011	ABC-type metal ion transport system permease component
KXJ75_19420	COG1464	Belongs to the NlpA lipoprotein family
KXJ75_19430	COG0840	transmembrane signaling receptor activity
KXJ75_19475	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
KXJ75_19490	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
KXJ75_19495	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
KXJ75_19500	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
KXJ75_19505	COG2716	regulation of RNA biosynthetic process
KXJ75_19510	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
KXJ75_19515	COG3013	Belongs to the UPF0304 family
KXJ75_19525	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
KXJ75_19530	COG0280	phosphate acetyltransferase
KXJ75_19530	COG0857	belongs to the CobB CobQ family
KXJ75_19535	COG0440	acetolactate synthase activity
KXJ75_19540	COG0028	Belongs to the TPP enzyme family
KXJ75_19550	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
KXJ75_19555	COG0671	phosphoesterase, PA-phosphatase related
KXJ75_19565	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
KXJ75_19570	COG0473	3-isopropylmalate dehydrogenase activity
KXJ75_19575	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
KXJ75_19580	COG0066	3-isopropylmalate dehydratase activity
KXJ75_19600	COG1178	ABC-type Fe3 transport system permease component
KXJ75_19605	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
KXJ75_19610	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
KXJ75_19620	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KXJ75_19710	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KXJ75_19715	COG1136	(ABC) transporter
KXJ75_19715	COG0577	efflux transmembrane transporter activity
KXJ75_19725	COG1912	Pfam S-adenosyl-l-methionine hydroxide adenosyltransferase
KXJ75_19735	COG0513	Belongs to the DEAD box helicase family
KXJ75_19790	COG0154	amidase activity
KXJ75_19795	COG2957	Belongs to the agmatine deiminase family
KXJ75_19815	COG1902	pentaerythritol trinitrate reductase activity
KXJ75_19840	COG3300	MHYT domain
KXJ75_19840	COG5001	Diguanylate cyclase
KXJ75_19845	COG2425	protein containing a von Willebrand factor type A (vWA) domain
KXJ75_19860	COG0456	acetyltransferase
KXJ75_19870	COG1022	Amp-dependent synthetase and ligase
KXJ75_19880	COG1794	racemase activity, acting on amino acids and derivatives
KXJ75_19895	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KXJ75_19935	COG0561	phosphatase activity
KXJ75_19965	COG1846	Transcriptional regulator
KXJ75_19970	COG2130	NADP-dependent
KXJ75_19995	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
KXJ75_20000	COG1640	4-alpha-glucanotransferase
KXJ75_20005	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
KXJ75_20015	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
KXJ75_20110	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
KXJ75_20115	COG2885	chlorophyll binding
KXJ75_20120	COG0823	Involved in the tonB-independent uptake of proteins
KXJ75_20135	COG0811	peptide transport
KXJ75_20140	COG0824	Thioesterase
KXJ75_20145	COG3790	cyd operon protein YbgE
KXJ75_20150	COG4890	Cyd operon protein YbgT
KXJ75_20155	COG1294	oxidase, subunit
KXJ75_20160	COG1271	oxidase subunit
KXJ75_20165	COG2255	four-way junction helicase activity
KXJ75_20170	COG0632	four-way junction helicase activity
KXJ75_20175	COG0442	prolyl-tRNA aminoacylation
KXJ75_20180	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
KXJ75_20185	COG4221	oxidoreductase activity
KXJ75_20215	COG4166	transmembrane transport
KXJ75_20225	COG0840	transmembrane signaling receptor activity
KXJ75_20230	COG3568	Endonuclease Exonuclease Phosphatase
KXJ75_20245	COG0513	Belongs to the DEAD box helicase family
KXJ75_20290	COG1448	Aminotransferase
KXJ75_20315	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
KXJ75_20350	COG0840	transmembrane signaling receptor activity
KXJ75_20365	COG0583	DNA-binding transcription factor activity
KXJ75_20370	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
KXJ75_20375	COG4208	sulfate ABC transporter
KXJ75_20380	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
KXJ75_20395	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
KXJ75_20430	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
KXJ75_20435	COG0564	pseudouridine synthase activity
KXJ75_20460	COG0459	protein refolding
KXJ75_20465	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
KXJ75_20470	COG0534	Mate efflux family protein
KXJ75_20475	COG3030	protein affecting phage T7 exclusion by the F plasmid
KXJ75_20480	COG1027	Aspartate ammonia-lyase
KXJ75_20485	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
KXJ75_20490	COG2918	glutathione biosynthetic process
KXJ75_20495	COG0612	Peptidase, M16
KXJ75_20500	COG1238	metal cluster binding
KXJ75_20505	COG1064	alcohol dehydrogenase
KXJ75_20540	COG0359	binds to the 23S rRNA
KXJ75_20545	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
KXJ75_20550	COG0360	Binds together with S18 to 16S ribosomal RNA
KXJ75_20555	COG1914	H( )-stimulated, divalent metal cation uptake system
KXJ75_20560	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
KXJ75_20570	COG2153	protein acetylation
KXJ75_20580	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KXJ75_20585	COG0557	exoribonuclease II activity
KXJ75_20605	COG1854	S-ribosylhomocysteine lyase activity
KXJ75_20620	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
KXJ75_20620	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
KXJ75_20630	COG5433	transposase activity
KXJ75_20655	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
KXJ75_20660	COG1047	Peptidyl-prolyl cis-trans
KXJ75_20665	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
KXJ75_20670	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
KXJ75_20675	COG0196	riboflavin kinase activity
KXJ75_20680	COG0728	peptidoglycan biosynthetic process
KXJ75_20685	COG0268	Binds directly to 16S ribosomal RNA
KXJ75_20690	COG0640	Transcriptional regulator
KXJ75_20695	COG0583	DNA-binding transcription factor activity
KXJ75_20705	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
KXJ75_20745	COG5433	transposase activity
KXJ75_20750	COG5642	Protein of unknown function (DUF2384)
KXJ75_20755	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
KXJ75_20765	COG2194	sulfuric ester hydrolase activity
KXJ75_20790	COG5433	transposase activity
KXJ75_20815	COG0659	secondary active sulfate transmembrane transporter activity
KXJ75_20830	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
KXJ75_20855	COG4974	Belongs to the 'phage' integrase family
KXJ75_20865	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
KXJ75_20875	COG1051	belongs to the nudix hydrolase family
KXJ75_20885	COG3066	DNA modification
KXJ75_20895	COG0335	large ribosomal subunit rRNA binding
KXJ75_20900	COG0336	Belongs to the RNA methyltransferase TrmD family
KXJ75_20905	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
KXJ75_20910	COG0228	four-way junction DNA binding
KXJ75_20915	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
KXJ75_20920	COG4137	Cytochrome C assembly protein
KXJ75_20925	COG4536	flavin adenine dinucleotide binding
KXJ75_20935	COG1017	nitric oxide dioxygenase activity
KXJ75_20935	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
KXJ75_20940	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
KXJ75_20945	COG0039	L-malate dehydrogenase activity
KXJ75_20950	COG4160	amino acid transport
KXJ75_20955	COG4215	(ABC) transporter
KXJ75_20960	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KXJ75_20965	COG1126	abc transporter atp-binding protein
KXJ75_20970	COG1438	arginine binding
KXJ75_20975	COG2837	iron assimilation
KXJ75_20980	COG3842	ATPase activity
KXJ75_20990	COG1840	ABC-type Fe3 transport system, periplasmic component
KXJ75_20995	COG0347	Belongs to the P(II) protein family
KXJ75_21010	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
KXJ75_21015	COG0583	DNA-binding transcription factor activity
KXJ75_21035	COG2610	gluconate transmembrane transporter activity
KXJ75_21040	COG3835	regulator
KXJ75_21045	COG3112	Uncharacterised protein family (UPF0231)
KXJ75_21065	COG1872	DUF167
KXJ75_21070	COG0762	integral membrane protein
KXJ75_21075	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
KXJ75_21080	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
KXJ75_21095	COG3022	response to hydroperoxide
KXJ75_21100	COG0513	Belongs to the DEAD box helicase family
KXJ75_21105	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
KXJ75_21125	COG0735	belongs to the Fur family
KXJ75_21130	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
KXJ75_21145	COG0776	regulation of translation
KXJ75_21150	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
KXJ75_21160	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
KXJ75_21175	COG0560	Phosphoserine phosphatase
KXJ75_21185	COG3064	Membrane
KXJ75_21200	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
KXJ75_21205	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
KXJ75_21210	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
KXJ75_21220	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
KXJ75_21225	COG0084	hydrolase, TatD family'
KXJ75_21230	COG2165	general secretion pathway protein
KXJ75_21290	COG5433	transposase activity
KXJ75_21310	COG5433	transposase activity
KXJ75_21320	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
KXJ75_21325	COG0004	ammonium transporteR
KXJ75_21340	COG0795	lipopolysaccharide-transporting ATPase activity
KXJ75_21345	COG0795	lipopolysaccharide-transporting ATPase activity
KXJ75_21350	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
KXJ75_21355	COG2927	DNA polymerase III (CHI subunit)
KXJ75_21360	COG0525	valine-tRNA ligase activity
KXJ75_21365	COG1253	flavin adenine dinucleotide binding
KXJ75_21370	COG0586	Pfam SNARE associated Golgi protein
KXJ75_21375	COG1686	Belongs to the peptidase S11 family
KXJ75_21415	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
KXJ75_21425	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
KXJ75_21435	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
KXJ75_21440	COG1546	Belongs to the CinA family
KXJ75_21465	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
KXJ75_21495	COG0732	type I restriction modification DNA specificity domain
KXJ75_21510	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
KXJ75_21530	COG5433	transposase activity
KXJ75_21545	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
KXJ75_21575	COG0739	heme binding
KXJ75_21595	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
KXJ75_21600	COG1121	(ABC) transporter
KXJ75_21605	COG1108	ABC-type Mn2 Zn2 transport systems permease components
KXJ75_21620	COG1573	uracil-dna glycosylase
KXJ75_21625	COG2962	Rard protein
KXJ75_21630	COG2827	Endonuclease containing a URI domain
KXJ75_21645	COG1842	Phage shock protein A
KXJ75_21650	COG0204	Acyl-transferase
KXJ75_21670	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KXJ75_21735	COG5433	transposase activity
KXJ75_21755	COG1289	transmembrane transporter activity
KXJ75_21760	COG1566	PFAM secretion protein HlyD family protein
KXJ75_21775	COG1051	belongs to the nudix hydrolase family
KXJ75_21780	COG3150	esterase
KXJ75_21790	COG3151	Protein conserved in bacteria
KXJ75_21795	COG0494	nUDIX hydrolase
KXJ75_21805	COG1538	Outer membrane efflux protein
KXJ75_21810	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
KXJ75_21810	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
KXJ75_21815	COG1560	Kdo2-lipid A biosynthetic process
KXJ75_21820	COG0737	Belongs to the 5'-nucleotidase family
KXJ75_21830	COG2771	luxR family
KXJ75_21840	COG2969	positive regulation of protein catabolic process
KXJ75_21845	COG0625	glutathione transferase activity
KXJ75_21850	COG2857	Cytochrome c1
KXJ75_21855	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
KXJ75_21860	COG0723	plastoquinol--plastocyanin reductase activity
KXJ75_21865	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
KXJ75_21870	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
KXJ75_21875	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
KXJ75_21885	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KXJ75_21890	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KXJ75_21920	COG3964	amidohydrolase
KXJ75_21940	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
KXJ75_21945	COG1660	Displays ATPase and GTPase activities
KXJ75_21950	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
KXJ75_21960	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
KXJ75_21965	COG1137	ATPase activity
KXJ75_21970	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
KXJ75_21975	COG3117	lipopolysaccharide transmembrane transporter activity
KXJ75_21980	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
KXJ75_21985	COG0517	IMP dehydrogenase activity
KXJ75_21985	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
KXJ75_21990	COG1127	ABC transporter
KXJ75_21995	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
KXJ75_22000	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
KXJ75_22005	COG2854	intermembrane phospholipid transfer
KXJ75_22015	COG5007	Belongs to the BolA IbaG family
KXJ75_22020	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
KXJ75_22025	COG0312	modulator of DNA gyrase
KXJ75_22030	COG3028	Belongs to the UPF0307 family
KXJ75_22040	COG2926	Belongs to the UPF0265 family
KXJ75_22080	COG1396	sequence-specific DNA binding
KXJ75_22085	COG3135	benzoate transporter
KXJ75_22115	COG0840	transmembrane signaling receptor activity
KXJ75_22120	COG3047	cAMP biosynthetic process
KXJ75_22130	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
KXJ75_22135	COG2197	response regulator
KXJ75_22160	COG1278	Cold shock
KXJ75_22190	COG3706	GGDEF domain
KXJ75_22195	COG0347	Belongs to the P(II) protein family
KXJ75_22200	COG0004	ammonium transporteR
KXJ75_22210	COG0346	lactoylglutathione lyase activity
KXJ75_22240	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
KXJ75_22250	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
KXJ75_22260	COG2259	Doxx family
KXJ75_22265	COG1741	Belongs to the pirin family
KXJ75_22275	COG0583	DNA-binding transcription factor activity
KXJ75_22305	COG1175	transmembrane transport
KXJ75_22315	COG3842	ATPase activity
KXJ75_22350	COG0456	acetyltransferase
KXJ75_22350	COG0454	-acetyltransferase
KXJ75_22355	COG0753	catalase activity
KXJ75_22375	COG0671	phosphoesterase, PA-phosphatase related
KXJ75_22380	COG0628	permease
KXJ75_22400	COG1461	Dihydroxyacetone kinase
KXJ75_22405	COG2376	Dihydroxyacetone kinase
KXJ75_22420	COG2252	PERMEase
KXJ75_22490	COG5433	transposase activity
KXJ75_22500	COG3311	Transcriptional regulator
KXJ75_22545	COG2003	Belongs to the UPF0758 family
KXJ75_22640	COG3318	Belongs to the UPF0149 family
KXJ75_22640	COG3012	SEC-C Motif Domain Protein
KXJ75_22650	COG3318	Belongs to the UPF0149 family
KXJ75_22650	COG3012	SEC-C Motif Domain Protein
KXJ75_22685	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
KXJ75_22690	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
KXJ75_22695	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
KXJ75_22700	COG0049	tRNA binding
KXJ75_22705	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
KXJ75_22710	COG2168	tRNA wobble position uridine thiolation
KXJ75_22725	COG0251	oxidation-reduction process
KXJ75_22730	COG2964	Protein conserved in bacteria
KXJ75_22740	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
KXJ75_22745	COG0085	RNA polymerase activity
KXJ75_22750	COG0222	ribosome binding
KXJ75_22755	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
KXJ75_22760	COG0081	regulation of translation
KXJ75_22765	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
KXJ75_22770	COG0250	Participates in transcription elongation, termination and antitermination
KXJ75_22785	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
KXJ75_22810	COG0812	UDP-N-acetylmuramate dehydrogenase activity
KXJ75_22815	COG0569	domain protein
KXJ75_22820	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
KXJ75_22830	COG3005	denitrification pathway
KXJ75_22835	COG0243	molybdopterin cofactor binding
KXJ75_22885	COG2204	response regulator
KXJ75_22895	COG2205	protein histidine kinase activity
KXJ75_22915	COG1028	Short-chain dehydrogenase reductase Sdr
KXJ75_22920	COG0517	IMP dehydrogenase activity
KXJ75_22920	COG0516	GMP reductase activity
KXJ75_22930	COG1522	sequence-specific DNA binding
KXJ75_22935	COG2502	aspartate--ammonia ligase
KXJ75_22940	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
KXJ75_22945	COG0542	response to heat
KXJ75_22955	COG0564	pseudouridine synthase activity
KXJ75_22960	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
KXJ75_22970	COG3681	Belongs to the UPF0597 family
KXJ75_22980	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
KXJ75_22985	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
KXJ75_22990	COG1979	alcohol dehydrogenase
KXJ75_22995	COG2207	Transcriptional regulator
KXJ75_23000	COG3040	lipid binding
KXJ75_23035	COG0540	Belongs to the ATCase OTCase family
KXJ75_23040	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
KXJ75_23045	COG1438	arginine binding
KXJ75_23050	COG1288	antiporter activity
KXJ75_23055	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
KXJ75_23090	COG1129	ABC transporter
KXJ75_23105	COG3250	beta-galactosidase activity
KXJ75_23110	COG1609	Transcriptional regulator
KXJ75_23115	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
KXJ75_23125	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
KXJ75_23130	COG2017	converts alpha-aldose to the beta-anomer
KXJ75_23140	COG2211	Major facilitator Superfamily
KXJ75_23150	COG1609	Transcriptional regulator
KXJ75_23165	COG1175	transmembrane transport
KXJ75_23180	COG3940	Belongs to the glycosyl hydrolase 43 family
KXJ75_23205	COG4580	involved in the transport of maltose and maltodextrins
KXJ75_23210	COG0667	Aldo Keto reductase
KXJ75_23215	COG1968	undecaprenyl-diphosphatase activity
KXJ75_23220	COG3806	Anti-sigma factor
KXJ75_23225	COG1595	DNA-templated transcription, initiation
KXJ75_23235	COG0018	arginyl-trna synthetase
KXJ75_23245	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
KXJ75_23250	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
KXJ75_23270	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KXJ75_23275	COG1131	(ABC) transporter
KXJ75_23280	COG0842	Transport permease protein
KXJ75_23285	COG0842	Transport permease protein
KXJ75_23290	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
KXJ75_23300	COG2116	formate transmembrane transporter activity
KXJ75_23305	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
KXJ75_23305	COG1648	precorrin-2 dehydrogenase activity
KXJ75_23310	COG2239	Acts as a magnesium transporter
KXJ75_23320	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
KXJ75_23330	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
KXJ75_23340	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
KXJ75_23350	COG0514	ATP-dependent DNA helicase (RecQ)
KXJ75_23355	COG2050	protein possibly involved in aromatic compounds catabolism
KXJ75_23375	COG2258	MOSC domain
KXJ75_23380	COG1177	transmembrane transport
KXJ75_23385	COG1176	ABC-type spermidine putrescine transport system, permease component I
KXJ75_23390	COG3842	ATPase activity
KXJ75_23410	COG0174	glutamine synthetase
KXJ75_23430	COG3045	CreA protein
KXJ75_23435	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KXJ75_23440	COG0443	Heat shock 70 kDa protein
KXJ75_23455	COG0366	Alpha amylase catalytic
KXJ75_23470	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
KXJ75_23475	COG0745	RESPONSE REGULATOR receiver
KXJ75_23480	COG2205	protein histidine kinase activity
KXJ75_23490	COG0281	malic enzyme
KXJ75_23495	COG0702	epimerase
KXJ75_23500	COG0254	rRNA binding
KXJ75_23505	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
KXJ75_23520	COG0129	dihydroxy-acid dehydratase activity
KXJ75_23530	COG3978	acetolactate synthase activity
KXJ75_23540	COG0606	chelatase, subunit chli
KXJ75_23545	COG0204	Acyl-transferase
KXJ75_23550	COG0204	Acyl-transferase
KXJ75_23555	COG1683	Conserved Protein
KXJ75_23565	COG1335	isochorismatase
KXJ75_23575	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
KXJ75_23580	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
KXJ75_23585	COG3639	organic phosphonate transmembrane transporter activity
KXJ75_23590	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
KXJ75_23595	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
KXJ75_23605	COG3084	Protein conserved in bacteria
KXJ75_23610	COG5001	Diguanylate cyclase
KXJ75_23610	COG4251	negative regulation of phosphorylation
KXJ75_23610	COG3706	GGDEF domain
KXJ75_23610	COG2203	Gaf domain
KXJ75_23625	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
KXJ75_23630	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
KXJ75_23635	COG1561	YicC-like family, N-terminal region
KXJ75_23645	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
KXJ75_23650	COG3177	Filamentation induced by cAMP protein fic
KXJ75_23665	COG2186	Transcriptional regulator
KXJ75_23705	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
KXJ75_23710	COG0732	type I restriction modification DNA specificity domain
KXJ75_23740	COG0732	type I restriction modification DNA specificity domain
KXJ75_23745	COG3171	Protein conserved in bacteria
KXJ75_23760	COG1519	Transferase
KXJ75_23765	COG0859	PFAM glycosyl transferase family 9
KXJ75_23770	COG0463	Glycosyl transferase, family 2
KXJ75_23775	COG0859	PFAM glycosyl transferase family 9
KXJ75_23780	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
KXJ75_23785	COG2990	Protein conserved in bacteria
KXJ75_23790	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
KXJ75_23800	COG0267	Belongs to the bacterial ribosomal protein bL33 family
KXJ75_23805	COG0227	Belongs to the bacterial ribosomal protein bL28 family
KXJ75_23810	COG2003	Belongs to the UPF0758 family
KXJ75_23815	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
KXJ75_23820	COG0756	dUTP diphosphatase activity
KXJ75_23825	COG1309	transcriptional regulator
KXJ75_23830	COG0668	transmembrane transport
KXJ75_23840	COG0166	Belongs to the GPI family
KXJ75_23845	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
KXJ75_23850	COG0583	DNA-binding transcription factor activity
KXJ75_23860	COG1042	CoA-binding domain protein
KXJ75_23860	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KXJ75_23860	COG0045	succinate-CoA ligase (ADP-forming) activity
KXJ75_23890	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
KXJ75_23895	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
KXJ75_23900	COG1739	Uncharacterized protein family UPF0029
KXJ75_23905	COG0006	proline dipeptidase activity
KXJ75_23910	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
KXJ75_23915	COG1024	Enoyl-CoA hydratase
KXJ75_23915	COG1250	3-hydroxyacyl-CoA dehydrogenase
KXJ75_23920	COG0183	Belongs to the thiolase family
KXJ75_23935	COG1653	transport
KXJ75_23945	COG0425	Belongs to the sulfur carrier protein TusA family
KXJ75_23950	COG0251	oxidation-reduction process
KXJ75_23955	COG2885	chlorophyll binding
KXJ75_23980	COG2818	Glycosylase
KXJ75_23985	COG0752	glycyl-tRNA synthetase alpha subunit
KXJ75_23990	COG0751	glycine-tRNA ligase activity
KXJ75_24025	COG3033	Beta-eliminating lyase
KXJ75_24035	COG0348	domain, Protein
KXJ75_24045	COG0446	pyridine nucleotide-disulphide oxidoreductase
KXJ75_24050	COG1773	rubredoxin
KXJ75_24050	COG0426	domain, Protein
KXJ75_24055	COG3604	Transcriptional regulator
KXJ75_24060	COG1609	Transcriptional regulator
KXJ75_24105	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KXJ75_24125	COG2960	long-chain fatty acid transporting porin activity
KXJ75_24135	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
KXJ75_24150	COG3118	belongs to the thioredoxin family
KXJ75_24155	COG0513	Belongs to the DEAD box helicase family
KXJ75_24160	COG0248	Ppx GppA phosphatase
KXJ75_24175	COG0742	ribosomal rna small subunit methyltransferase
KXJ75_24195	COG0084	hydrolase, TatD family'
KXJ75_24200	COG0805	protein transport
KXJ75_24205	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
KXJ75_24210	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
KXJ75_24215	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
KXJ75_24220	COG3165	ubiquinone biosynthetic process from chorismate
KXJ75_24230	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
KXJ75_24235	COG0402	S-adenosylhomocysteine deaminase activity
KXJ75_24275	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
KXJ75_24280	COG0848	biopolymer transport protein
KXJ75_24285	COG0811	peptide transport
KXJ75_24290	COG0811	peptide transport
KXJ75_24300	COG2771	luxR family
KXJ75_24330	COG5433	transposase activity
KXJ75_24355	COG1017	nitric oxide dioxygenase activity
KXJ75_24355	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
KXJ75_24400	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
KXJ75_24405	COG1349	DNA-binding transcription factor activity
KXJ75_24410	COG0745	RESPONSE REGULATOR receiver
KXJ75_24415	COG2205	protein histidine kinase activity
KXJ75_24425	COG4452	Inner membrane protein CreD
KXJ75_24430	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
KXJ75_24435	COG0355	proton-transporting ATP synthase activity, rotational mechanism
KXJ75_24440	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
KXJ75_24445	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
KXJ75_24450	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
KXJ75_24455	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
KXJ75_24460	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
KXJ75_24470	COG0356	it plays a direct role in the translocation of protons across the membrane
KXJ75_24480	COG1475	DNA binding
KXJ75_24485	COG1192	Involved in chromosome partitioning
KXJ75_24490	COG0357	Ribosomal RNA small subunit methyltransferase G
KXJ75_24495	COG0445	tRNA wobble uridine modification
KXJ75_24500	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
KXJ75_24505	COG4774	siderophore transport
KXJ75_24510	COG4615	Cyclic peptide transporter
KXJ75_24515	COG1120	ATPase activity
KXJ75_24520	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
KXJ75_24620	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
KXJ75_24660	COG0789	Transcriptional regulator
KXJ75_24675	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
KXJ75_24685	COG3012	SEC-C Motif Domain Protein
KXJ75_24685	COG3318	Belongs to the UPF0149 family
KXJ75_24750	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
KXJ75_24770	COG0706	membrane insertase activity
KXJ75_24775	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
KXJ75_24780	COG0594	ribonuclease P activity
KXJ75_24785	COG0230	Belongs to the bacterial ribosomal protein bL34 family
KXJ75_24790	COG1126	abc transporter atp-binding protein