locus-tag	class	description
E2P79_00005	COG0716	FMN binding
E2P79_00010	COG0445	tRNA wobble uridine modification
E2P79_00015	COG0357	Ribosomal RNA small subunit methyltransferase G
E2P79_00020	COG1192	Involved in chromosome partitioning
E2P79_00025	COG1475	DNA binding
E2P79_00035	COG0356	it plays a direct role in the translocation of protons across the membrane
E2P79_00045	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
E2P79_00050	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
E2P79_00055	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
E2P79_00060	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
E2P79_00065	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
E2P79_00070	COG0355	proton-transporting ATP synthase activity, rotational mechanism
E2P79_00080	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
E2P79_00085	COG4452	Inner membrane protein CreD
E2P79_00100	COG0745	RESPONSE REGULATOR receiver
E2P79_00165	COG1561	YicC-like family, N-terminal region
E2P79_00175	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
E2P79_00180	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
E2P79_00190	COG0248	Ppx GppA phosphatase
E2P79_00195	COG0513	Belongs to the DEAD box helicase family
E2P79_00200	COG3118	belongs to the thioredoxin family
E2P79_00205	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
E2P79_00215	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
E2P79_00225	COG5001	Diguanylate cyclase
E2P79_00240	COG0668	transmembrane transport
E2P79_00245	COG1309	transcriptional regulator
E2P79_00250	COG0756	dUTP diphosphatase activity
E2P79_00255	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
E2P79_00260	COG2003	Belongs to the UPF0758 family
E2P79_00265	COG0227	Belongs to the bacterial ribosomal protein bL28 family
E2P79_00270	COG0267	Belongs to the bacterial ribosomal protein bL33 family
E2P79_00280	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
E2P79_00285	COG2990	Protein conserved in bacteria
E2P79_00295	COG0859	PFAM glycosyl transferase family 9
E2P79_00300	COG0463	Glycosyl transferase, family 2
E2P79_00305	COG0366	Alpha amylase catalytic
E2P79_00320	COG0443	Heat shock 70 kDa protein
E2P79_00325	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
E2P79_00330	COG3045	CreA protein
E2P79_00345	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
E2P79_00350	COG0174	glutamine synthetase
E2P79_00370	COG3842	ATPase activity
E2P79_00375	COG1176	ABC-type spermidine putrescine transport system, permease component I
E2P79_00380	COG1177	transmembrane transport
E2P79_00385	COG2258	MOSC domain
E2P79_00420	COG2249	NAD(P)H dehydrogenase (quinone) activity
E2P79_00430	COG1770	oligopeptidase
E2P79_00435	COG0251	oxidation-reduction process
E2P79_00440	COG0425	Belongs to the sulfur carrier protein TusA family
E2P79_00460	COG0583	DNA-binding transcription factor activity
E2P79_00465	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
E2P79_00475	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
E2P79_00480	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
E2P79_00500	COG1609	Transcriptional regulator
E2P79_00505	COG3250	beta-galactosidase activity
E2P79_00510	COG2731	YhcH YjgK YiaL family protein
E2P79_00515	COG0531	amino acid
E2P79_00520	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
E2P79_00525	COG0531	amino acid
E2P79_00540	COG5433	transposase activity
E2P79_00560	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
E2P79_00565	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
E2P79_00575	COG0254	rRNA binding
E2P79_00585	COG0281	malic enzyme
E2P79_00590	COG2205	protein histidine kinase activity
E2P79_00595	COG0745	RESPONSE REGULATOR receiver
E2P79_00610	COG0745	RESPONSE REGULATOR receiver
E2P79_00615	COG0183	Belongs to the thiolase family
E2P79_00620	COG1024	Enoyl-CoA hydratase
E2P79_00620	COG1250	3-hydroxyacyl-CoA dehydrogenase
E2P79_00625	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
E2P79_00630	COG0006	proline dipeptidase activity
E2P79_00635	COG1739	Uncharacterized protein family UPF0029
E2P79_00640	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
E2P79_00680	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
E2P79_00685	COG0402	S-adenosylhomocysteine deaminase activity
E2P79_00690	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
E2P79_00695	COG2226	methyltransferase
E2P79_00700	COG3165	ubiquinone biosynthetic process from chorismate
E2P79_00705	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
E2P79_00715	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
E2P79_00720	COG0805	protein transport
E2P79_00725	COG0084	hydrolase, TatD family'
E2P79_00735	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
E2P79_00740	COG4191	Histidine kinase
E2P79_00740	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
E2P79_00750	COG5001	Diguanylate cyclase
E2P79_00755	COG0742	ribosomal rna small subunit methyltransferase
E2P79_00760	COG3714	YhhN family
E2P79_00765	COG2937	Belongs to the GPAT DAPAT family
E2P79_00770	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
E2P79_00780	COG0534	Mate efflux family protein
E2P79_00785	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
E2P79_00790	COG2205	protein histidine kinase activity
E2P79_00795	COG0745	RESPONSE REGULATOR receiver
E2P79_00805	COG1045	serine acetyltransferase
E2P79_00815	COG3074	FtsZ-dependent cytokinesis
E2P79_00820	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
E2P79_00825	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
E2P79_00825	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
E2P79_00830	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
E2P79_00885	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
E2P79_00890	COG1288	antiporter activity
E2P79_00905	COG4221	oxidoreductase activity
E2P79_00915	COG2199	diguanylate cyclase activity
E2P79_00915	COG2203	Gaf domain
E2P79_00925	COG4191	Histidine kinase
E2P79_00950	COG2207	Transcriptional regulator
E2P79_00960	COG0569	domain protein
E2P79_00975	COG2056	Na+-H+ antiporter family
E2P79_00980	COG3385	transposase activity
E2P79_00985	COG1072	(Pantothenic acid kinase))
E2P79_01005	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
E2P79_01015	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
E2P79_01020	COG0250	Participates in transcription elongation, termination and antitermination
E2P79_01025	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
E2P79_01030	COG0081	regulation of translation
E2P79_01035	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
E2P79_01045	COG0085	RNA polymerase activity
E2P79_01050	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
E2P79_01055	COG2964	Protein conserved in bacteria
E2P79_01060	COG0251	oxidation-reduction process
E2P79_01065	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
E2P79_01070	COG2923	Belongs to the DsrF TusC family
E2P79_01075	COG2168	tRNA wobble position uridine thiolation
E2P79_01080	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
E2P79_01085	COG0049	tRNA binding
E2P79_01090	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
E2P79_01095	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
E2P79_01135	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
E2P79_01140	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
E2P79_01150	COG0018	arginyl-trna synthetase
E2P79_01160	COG4776	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction
E2P79_01165	COG1289	transmembrane transporter activity
E2P79_01170	COG0210	DNA helicase
E2P79_01215	COG0166	Belongs to the GPI family
E2P79_01225	COG2217	Heavy metal translocating P-type atpase
E2P79_01235	COG4251	negative regulation of phosphorylation
E2P79_01235	COG2203	Gaf domain
E2P79_01235	COG5001	Diguanylate cyclase
E2P79_01235	COG3706	GGDEF domain
E2P79_01240	COG3084	Protein conserved in bacteria
E2P79_01255	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
E2P79_01260	COG2183	response to ionizing radiation
E2P79_01265	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
E2P79_01275	COG0745	RESPONSE REGULATOR receiver
E2P79_01280	COG2205	protein histidine kinase activity
E2P79_01290	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
E2P79_01310	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
E2P79_01315	COG1459	type II secretion system
E2P79_01320	COG2165	general secretion pathway protein
E2P79_01330	COG2165	general secretion pathway protein
E2P79_01335	COG4795	General secretion pathway protein
E2P79_01365	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
E2P79_01375	COG1902	pentaerythritol trinitrate reductase activity
E2P79_01380	COG1280	lysine exporter protein (LysE YggA)
E2P79_01385	COG1011	Hydrolase
E2P79_01390	COG0494	nUDIX hydrolase
E2P79_01395	COG1218	3'(2'),5'-bisphosphate nucleotidase
E2P79_01410	COG0189	ligase activity
E2P79_01470	COG0513	Belongs to the DEAD box helicase family
E2P79_01490	COG0454	-acetyltransferase
E2P79_01505	COG2391	methyltransferase activity
E2P79_01520	COG3932	Exopolysaccharide synthesis, ExoD
E2P79_01525	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
E2P79_01530	COG0561	phosphatase activity
E2P79_01545	COG3133	Outer membrane lipoprotein
E2P79_01550	COG0456	acetyltransferase
E2P79_01565	COG0006	proline dipeptidase activity
E2P79_01565	COG0006	proline dipeptidase activity
E2P79_01575	COG3038	cytochrome b561
E2P79_01590	COG1639	'signal transduction protein
E2P79_01595	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
E2P79_01635	COG0745	RESPONSE REGULATOR receiver
E2P79_01675	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
E2P79_01680	COG2200	EAL domain
E2P79_01690	COG1448	Aminotransferase
E2P79_01695	COG2194	sulfuric ester hydrolase activity
E2P79_01710	COG1215	transferase activity, transferring glycosyl groups
E2P79_01715	COG1215	transferase activity, transferring glycosyl groups
E2P79_01770	COG1840	ABC-type Fe3 transport system, periplasmic component
E2P79_01785	COG2837	iron assimilation
E2P79_01790	COG1438	arginine binding
E2P79_01795	COG1126	abc transporter atp-binding protein
E2P79_01805	COG4215	(ABC) transporter
E2P79_01810	COG4160	amino acid transport
E2P79_01815	COG0039	L-malate dehydrogenase activity
E2P79_01820	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
E2P79_01835	COG4536	flavin adenine dinucleotide binding
E2P79_01840	COG4137	Cytochrome C assembly protein
E2P79_01845	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
E2P79_01850	COG0228	four-way junction DNA binding
E2P79_01855	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
E2P79_01860	COG0336	Belongs to the RNA methyltransferase TrmD family
E2P79_01865	COG0335	large ribosomal subunit rRNA binding
E2P79_01875	COG3066	DNA modification
E2P79_01880	COG1051	belongs to the nudix hydrolase family
E2P79_01890	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
E2P79_01895	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
E2P79_01900	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
E2P79_01910	COG0583	DNA-binding transcription factor activity
E2P79_01915	COG0640	Transcriptional regulator
E2P79_01920	COG0268	Binds directly to 16S ribosomal RNA
E2P79_01925	COG0728	peptidoglycan biosynthetic process
E2P79_01930	COG0196	riboflavin kinase activity
E2P79_01935	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
E2P79_01940	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
E2P79_01945	COG1047	Peptidyl-prolyl cis-trans
E2P79_01950	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
E2P79_01990	COG0583	DNA-binding transcription factor activity
E2P79_01995	COG1741	Belongs to the pirin family
E2P79_02000	COG2259	Doxx family
E2P79_02005	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
E2P79_02015	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
E2P79_02020	COG0513	Belongs to the DEAD box helicase family
E2P79_02035	COG0531	amino acid
E2P79_02040	COG3916	Acyl-homoserine-lactone synthase
E2P79_02045	COG2771	luxR family
E2P79_02055	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
E2P79_02060	COG3706	GGDEF domain
E2P79_02065	COG3047	cAMP biosynthetic process
E2P79_02085	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
E2P79_02090	COG2949	membrane
E2P79_02095	COG3291	Pkd domain containing protein
E2P79_02115	COG3188	usher protein
E2P79_02125	COG3539	Fimbrial protein
E2P79_02145	COG1441	menaquinone biosynthetic process
E2P79_02150	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
E2P79_02160	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
E2P79_02165	COG1169	isochorismate synthase
E2P79_02170	COG1575	Belongs to the MenA family. Type 1 subfamily
E2P79_02175	COG0840	transmembrane signaling receptor activity
E2P79_02245	COG2926	Belongs to the UPF0265 family
E2P79_02260	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
E2P79_02280	COG1929	Belongs to the glycerate kinase type-1 family
E2P79_02285	COG2610	gluconate transmembrane transporter activity
E2P79_02290	COG3835	regulator
E2P79_02295	COG3112	Uncharacterised protein family (UPF0231)
E2P79_02315	COG2252	PERMEase
E2P79_02320	COG2376	Dihydroxyacetone kinase
E2P79_02325	COG1461	Dihydroxyacetone kinase
E2P79_02340	COG0583	DNA-binding transcription factor activity
E2P79_02350	COG0628	permease
E2P79_02385	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
E2P79_02390	COG0540	Belongs to the ATCase OTCase family
E2P79_02405	COG0688	phosphatidylethanolamine metabolic process
E2P79_02410	COG1309	transcriptional regulator
E2P79_02420	COG0625	glutathione transferase activity
E2P79_02435	COG0840	transmembrane signaling receptor activity
E2P79_02440	COG3040	lipid binding
E2P79_02445	COG2207	Transcriptional regulator
E2P79_02450	COG1979	alcohol dehydrogenase
E2P79_02455	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
E2P79_02460	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
E2P79_02475	COG1522	sequence-specific DNA binding
E2P79_02480	COG2502	aspartate--ammonia ligase
E2P79_02490	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
E2P79_02495	COG1194	a g-specific adenine glycosylase
E2P79_02505	COG3409	Peptidoglycan-binding domain 1 protein
E2P79_02505	COG3267	Type II secretory pathway component ExeA
E2P79_02510	COG0617	tRNA 3'-terminal CCA addition
E2P79_02515	COG0306	phosphate transporter
E2P79_02520	COG1392	Phosphate transport regulator
E2P79_02530	COG1560	Kdo2-lipid A biosynthetic process
E2P79_02535	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
E2P79_02535	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
E2P79_02540	COG2827	Endonuclease containing a URI domain
E2P79_02550	COG2962	Rard protein
E2P79_02555	COG1573	uracil-dna glycosylase
E2P79_02565	COG0583	DNA-binding transcription factor activity
E2P79_02570	COG1108	ABC-type Mn2 Zn2 transport systems permease components
E2P79_02575	COG1121	(ABC) transporter
E2P79_02580	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
E2P79_02585	COG0739	heme binding
E2P79_02595	COG3068	Protein conserved in bacteria
E2P79_02615	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
E2P79_02620	COG1546	Belongs to the CinA family
E2P79_02625	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
E2P79_02630	COG2137	regulation of response to DNA damage stimulus
E2P79_02635	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
E2P79_02640	COG0527	aspartate kinase activity
E2P79_02645	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
E2P79_02690	COG1376	ErfK ybiS ycfS ynhG family protein
E2P79_02705	COG0312	modulator of DNA gyrase
E2P79_02710	COG0312	modulator of DNA gyrase
E2P79_02715	COG0716	FMN binding
E2P79_02720	COG4974	Belongs to the 'phage' integrase family
E2P79_02725	COG3706	GGDEF domain
E2P79_02730	COG1970	mechanosensitive ion channel activity
E2P79_02740	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
E2P79_02755	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
E2P79_02760	COG0583	DNA-binding transcription factor activity
E2P79_02765	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
E2P79_02795	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
E2P79_02800	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
E2P79_02810	COG0338	D12 class N6 adenine-specific DNA methyltransferase
E2P79_02815	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
E2P79_02825	COG0180	Tryptophanyl-tRNA synthetase
E2P79_02840	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
E2P79_02850	COG1012	belongs to the aldehyde dehydrogenase family
E2P79_02865	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
E2P79_02870	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
E2P79_02875	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
E2P79_02880	COG0175	sulfate reduction
E2P79_02885	COG3447	MASE1 domain protein
E2P79_02885	COG5001	Diguanylate cyclase
E2P79_02885	COG5002	protein histidine kinase activity
E2P79_02890	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
E2P79_02905	COG0523	cobalamin synthesis protein
E2P79_02910	COG0477	Major facilitator Superfamily
E2P79_02925	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
E2P79_02930	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
E2P79_02965	COG3029	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
E2P79_02970	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
E2P79_02975	COG1053	succinate dehydrogenase
E2P79_02990	COG0813	purine-nucleoside phosphorylase activity
E2P79_03000	COG0490	domain, Protein
E2P79_03000	COG0471	metal ion transport
E2P79_03045	COG0012	GTP binding
E2P79_03050	COG0193	aminoacyl-tRNA hydrolase activity
E2P79_03060	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
E2P79_03065	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
E2P79_03070	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
E2P79_03075	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
E2P79_03080	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
E2P79_03085	COG2890	protein-(glutamine-N5) methyltransferase activity
E2P79_03095	COG2912	Transglutaminase-like superfamily
E2P79_03105	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
E2P79_03110	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
E2P79_03120	COG0585	pseudouridine synthase activity
E2P79_03125	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
E2P79_03130	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
E2P79_03135	COG1238	metal cluster binding
E2P79_03145	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
E2P79_03150	COG0776	regulation of translation
E2P79_03165	COG1872	DUF167
E2P79_03170	COG0762	integral membrane protein
E2P79_03175	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
E2P79_03180	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
E2P79_03195	COG3022	response to hydroperoxide
E2P79_03200	COG0513	Belongs to the DEAD box helicase family
E2P79_03205	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
E2P79_03225	COG0735	belongs to the Fur family
E2P79_03230	COG1007	ATP synthesis coupled electron transport
E2P79_03245	COG0713	ATP synthesis coupled electron transport
E2P79_03250	COG0839	Belongs to the complex I subunit 6 family
E2P79_03255	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
E2P79_03260	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
E2P79_03265	COG1034	ATP synthesis coupled electron transport
E2P79_03280	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
E2P79_03280	COG0649	NAD binding
E2P79_03285	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
E2P79_03290	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
E2P79_03295	COG1360	Flagellar Motor Protein
E2P79_03300	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
E2P79_03325	COG0745	RESPONSE REGULATOR receiver
E2P79_03330	COG3104	oligopeptide transport
E2P79_03335	COG1210	Utp--glucose-1-phosphate uridylyltransferase
E2P79_03340	COG1555	photosystem II stabilization
E2P79_03345	COG1218	3'(2'),5'-bisphosphate nucleotidase
E2P79_03350	COG2350	Protein conserved in bacteria
E2P79_03355	COG2917	probably involved in intracellular septation
E2P79_03360	COG0076	glutamate decarboxylase activity
E2P79_03365	COG0569	domain protein
E2P79_03365	COG2985	domain, Protein
E2P79_03385	COG1278	Cold shock
E2P79_03395	COG0840	transmembrane signaling receptor activity
E2P79_03400	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
E2P79_03405	COG3445	Acts as a radical domain for damaged PFL and possibly other radical proteins
E2P79_03415	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
E2P79_03430	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
E2P79_03435	COG1115	amino acid carrier protein
E2P79_03440	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
E2P79_03445	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
E2P79_03470	COG3706	GGDEF domain
E2P79_03475	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
E2P79_03480	COG1678	Uncharacterized ACR, COG1678
E2P79_03485	COG0189	ligase activity
E2P79_03490	COG1385	rRNA (uridine-N3-)-methyltransferase activity
E2P79_03500	COG3091	SprT-like family
E2P79_03510	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
E2P79_03575	COG0784	Response regulator, receiver
E2P79_03575	COG0835	chemotaxis
E2P79_03585	COG4181	ATPase activity
E2P79_03595	COG1090	epimerase
E2P79_03600	COG0857	belongs to the CobB CobQ family
E2P79_03600	COG0280	phosphate acetyltransferase
E2P79_03605	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
E2P79_03610	COG3092	negative regulation of chromosome organization
E2P79_03620	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
E2P79_03625	COG2716	regulation of RNA biosynthetic process
E2P79_03635	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
E2P79_03640	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
E2P79_03660	COG0142	geranyltranstransferase activity
E2P79_03665	COG1722	exodeoxyribonuclease VII activity
E2P79_03670	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
E2P79_03675	COG1360	Flagellar Motor Protein
E2P79_03680	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
E2P79_03690	COG1534	Rna-binding protein
E2P79_03695	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
E2P79_03700	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
E2P79_03705	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
E2P79_03710	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
E2P79_03715	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
E2P79_03730	COG0779	Required for maturation of 30S ribosomal subunits
E2P79_03735	COG0195	Participates in both transcription termination and antitermination
E2P79_03740	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
E2P79_03745	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
E2P79_03750	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
E2P79_03755	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
E2P79_03760	COG1185	polyribonucleotide nucleotidyltransferase activity
E2P79_03780	COG0463	Glycosyl transferase, family 2
E2P79_03795	COG2989	Protein conserved in bacteria
E2P79_03800	COG3108	Peptidase M15
E2P79_03815	COG0252	asparaginase activity
E2P79_03835	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
E2P79_03835	COG1263	PTS System
E2P79_03840	COG0366	Alpha amylase catalytic
E2P79_03845	COG0110	maltose O-acetyltransferase activity
E2P79_03875	COG1012	belongs to the aldehyde dehydrogenase family
E2P79_03880	COG1177	transmembrane transport
E2P79_03885	COG1176	ABC-type spermidine putrescine transport system, permease component I
E2P79_03890	COG3842	ATPase activity
E2P79_03895	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
E2P79_03900	COG0583	DNA-binding transcription factor activity
E2P79_03910	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
E2P79_03920	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
E2P79_03930	COG4232	protein-disulfide reductase activity
E2P79_03955	COG0583	DNA-binding transcription factor activity
E2P79_03965	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
E2P79_03975	COG0187	DNA topoisomerase II activity
E2P79_04005	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
E2P79_04035	COG4221	oxidoreductase activity
E2P79_04050	COG3811	Belongs to the UPF0386 family
E2P79_04055	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
E2P79_04065	COG4232	protein-disulfide reductase activity
E2P79_04080	COG1842	Phage shock protein A
E2P79_04100	COG1538	Outer membrane efflux protein
E2P79_04110	COG3151	Protein conserved in bacteria
E2P79_04120	COG3150	esterase
E2P79_04130	COG0305	Participates in initiation and elongation during chromosome replication
E2P79_04135	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
E2P79_04140	COG0432	Pfam Uncharacterised protein family UPF0047
E2P79_04160	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
E2P79_04165	COG1595	DNA-templated transcription, initiation
E2P79_04175	COG3026	antisigma factor binding
E2P79_04185	COG0481	GTPase activity
E2P79_04190	COG0681	Belongs to the peptidase S26 family
E2P79_04195	COG0571	ribonuclease III activity
E2P79_04200	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
E2P79_04205	COG1381	Involved in DNA repair and RecF pathway recombination
E2P79_04220	COG3023	N-Acetylmuramoyl-L-alanine amidase
E2P79_04225	COG4807	Protein conserved in bacteria
E2P79_04235	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
E2P79_04240	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
E2P79_04245	COG3956	TIGRFAM MazG family protein
E2P79_04250	COG0504	CTP synthase activity
E2P79_04255	COG0148	phosphopyruvate hydratase activity
E2P79_04370	COG0543	2 iron, 2 sulfur cluster binding
E2P79_04385	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
E2P79_04395	COG4166	transmembrane transport
E2P79_04410	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
E2P79_04415	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
E2P79_04420	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
E2P79_04435	COG1024	Enoyl-CoA hydratase
E2P79_04450	COG4221	oxidoreductase activity
E2P79_04455	COG2226	methyltransferase
E2P79_04460	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
E2P79_04465	COG1765	OsmC-like protein
E2P79_04480	COG3954	Phosphoribulokinase
E2P79_04495	COG0784	Response regulator, receiver
E2P79_04495	COG0835	chemotaxis
E2P79_04510	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
E2P79_04515	COG1047	Peptidyl-prolyl cis-trans
E2P79_04520	COG2900	Belongs to the SlyX family
E2P79_04530	COG0545	Peptidyl-prolyl cis-trans isomerase
E2P79_04535	COG1940	carbohydrate kinase activity
E2P79_04540	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
E2P79_04545	COG0126	phosphoglycerate kinase activity
E2P79_04565	COG5002	protein histidine kinase activity
E2P79_04565	COG2198	Histidine kinase
E2P79_04565	COG0784	Response regulator, receiver
E2P79_04590	COG0840	transmembrane signaling receptor activity
E2P79_04600	COG1464	Belongs to the NlpA lipoprotein family
E2P79_04605	COG2011	ABC-type metal ion transport system permease component
E2P79_04610	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
E2P79_04625	COG0848	biopolymer transport protein
E2P79_04630	COG0811	peptide transport
E2P79_04635	COG0811	peptide transport
E2P79_04650	COG4174	ABC transporter (Permease)
E2P79_04655	COG4239	(ABC) transporter, permease
E2P79_04665	COG0444	Belongs to the ABC transporter superfamily
E2P79_04670	COG4608	Belongs to the ABC transporter superfamily
E2P79_04715	COG0697	spore germination
E2P79_04745	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
E2P79_04755	COG0741	lytic transglycosylase activity
E2P79_04760	COG0471	metal ion transport
E2P79_04765	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
E2P79_04770	COG0174	glutamine synthetase
E2P79_04775	COG0840	transmembrane signaling receptor activity
E2P79_04785	COG0366	Alpha amylase catalytic
E2P79_04790	COG0545	Peptidyl-prolyl cis-trans isomerase
E2P79_04795	COG0071	Belongs to the small heat shock protein (HSP20) family
E2P79_04830	COG0159	tryptophan synthase activity
E2P79_04835	COG0133	tryptophan synthase activity
E2P79_04840	COG0135	phosphoribosylanthranilate isomerase activity
E2P79_04840	COG0134	indole-3-glycerol-phosphate synthase activity
E2P79_04845	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
E2P79_04850	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
E2P79_04850	COG0512	Glutamine amidotransferase of anthranilate synthase
E2P79_04855	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
E2P79_04870	COG0009	L-threonylcarbamoyladenylate synthase
E2P79_04880	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
E2P79_04925	COG0745	RESPONSE REGULATOR receiver
E2P79_04940	COG3227	Zinc metalloprotease (Elastase)
E2P79_04965	COG1283	sodium-dependent phosphate transmembrane transporter activity
E2P79_04980	COG0531	amino acid
E2P79_04985	COG0531	amino acid
E2P79_05000	COG0174	glutamine synthetase
E2P79_05015	COG5599	Phosphatase
E2P79_05020	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
E2P79_05020	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
E2P79_05020	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
E2P79_05025	COG0673	inositol 2-dehydrogenase activity
E2P79_05035	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
E2P79_05040	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
E2P79_05045	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
E2P79_05050	COG0251	oxidation-reduction process
E2P79_05060	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
E2P79_05075	COG2207	Transcriptional regulator
E2P79_05085	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
E2P79_05095	COG1196	nuclear chromosome segregation
E2P79_05095	COG3264	Mechanosensitive ion channel
E2P79_05100	COG2190	(PTS) system
E2P79_05110	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
E2P79_05115	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
E2P79_05120	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
E2P79_05135	COG2770	Histidine kinase
E2P79_05135	COG3437	response regulator, receiver
E2P79_05140	COG1720	tRNA m6t6A37 methyltransferase activity
E2P79_05155	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
E2P79_05160	COG4988	ABC transporter
E2P79_05180	COG0745	RESPONSE REGULATOR receiver
E2P79_05190	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
E2P79_05210	COG3381	protein complex oligomerization
E2P79_05220	COG3005	denitrification pathway
E2P79_05225	COG0745	RESPONSE REGULATOR receiver
E2P79_05230	COG1879	ABC-type sugar transport system periplasmic component
E2P79_05235	COG2205	protein histidine kinase activity
E2P79_05235	COG0784	Response regulator, receiver
E2P79_05235	COG2198	Histidine kinase
E2P79_05245	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
E2P79_05250	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
E2P79_05255	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
E2P79_05255	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
E2P79_05290	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
E2P79_05295	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
E2P79_05300	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
E2P79_05305	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
E2P79_05310	COG4172	Belongs to the ABC transporter superfamily
E2P79_05315	COG0747	negative chemotaxis
E2P79_05350	COG0739	heme binding
E2P79_05380	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
E2P79_05385	COG1666	GTP binding
E2P79_05390	COG3248	Nucleoside-binding outer membrane protein
E2P79_05395	COG2211	Major facilitator Superfamily
E2P79_05420	COG0271	Belongs to the BolA IbaG family
E2P79_05425	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
E2P79_05430	COG1805	sodium ion transport
E2P79_05435	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
E2P79_05440	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
E2P79_05445	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
E2P79_05450	COG2871	sodium ion transport
E2P79_05455	COG1477	protein flavinylation
E2P79_05460	COG2991	Protein conserved in bacteria
E2P79_05470	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
E2P79_05475	COG0840	transmembrane signaling receptor activity
E2P79_05480	COG0583	DNA-binding transcription factor activity
E2P79_05490	COG2363	Small membrane protein
E2P79_05495	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
E2P79_05505	COG0473	3-isopropylmalate dehydrogenase activity
E2P79_05510	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
E2P79_05515	COG1611	Belongs to the LOG family
E2P79_05530	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
E2P79_05530	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
E2P79_05540	COG0697	spore germination
E2P79_05545	COG5595	Zn-ribbon-containing, possibly nucleic-acid-binding protein (DUF2310)
E2P79_05570	COG3098	single-species biofilm formation
E2P79_05590	COG3590	peptidase
E2P79_05595	COG0037	tRNA processing
E2P79_05600	COG3706	GGDEF domain
E2P79_05635	COG0791	NLP P60 protein
E2P79_05665	COG1605	Chorismate mutase
E2P79_05665	COG0077	Prephenate dehydratase
E2P79_05690	COG3272	Protein of unknown function (DUF1722)
E2P79_05695	COG0789	Transcriptional regulator
E2P79_05710	COG0783	Belongs to the Dps family
E2P79_05715	COG1151	hydroxylamine reductase activity
E2P79_05720	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
E2P79_05725	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
E2P79_05735	COG3083	sulfuric ester hydrolase activity
E2P79_05740	COG3082	Protein of unknown function (DUF1414)
E2P79_05745	COG3081	Nucleoid-associated protein
E2P79_05755	COG1175	transmembrane transport
E2P79_05765	COG3842	ATPase activity
E2P79_05775	COG0596	Alpha beta hydrolase
E2P79_05790	COG0425	Belongs to the sulfur carrier protein TusA family
E2P79_05800	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
E2P79_05805	COG1393	Belongs to the ArsC family
E2P79_05820	COG0517	IMP dehydrogenase activity
E2P79_05825	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
E2P79_05830	COG0343	queuine tRNA-ribosyltransferase activity
E2P79_05835	COG1862	Preprotein translocase
E2P79_05840	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
E2P79_05845	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
E2P79_05885	COG1959	2 iron, 2 sulfur cluster binding
E2P79_05890	COG1104	cysteine desulfurase activity
E2P79_05895	COG0822	iron-sulfur transferase activity
E2P79_05905	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
E2P79_05910	COG0443	Heat shock 70 kDa protein
E2P79_05915	COG0633	Ferredoxin
E2P79_05925	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
E2P79_05940	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
E2P79_05950	COG0017	Asparaginyl-tRNA synthetase
E2P79_05965	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
E2P79_05970	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
E2P79_05975	COG0156	8-amino-7-oxononanoate synthase activity
E2P79_05985	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
E2P79_05990	COG0501	Belongs to the peptidase M48B family
E2P79_05995	COG0840	transmembrane signaling receptor activity
E2P79_06010	COG0493	'glutamate synthase
E2P79_06020	COG2841	Protein conserved in bacteria
E2P79_06025	COG0642	Histidine kinase
E2P79_06030	COG0745	RESPONSE REGULATOR receiver
E2P79_06040	COG0300	oxidoreductase activity
E2P79_06050	COG1022	Amp-dependent synthetase and ligase
E2P79_06065	COG0534	Mate efflux family protein
E2P79_06085	COG1342	Belongs to the UPF0251 family
E2P79_06115	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
E2P79_06125	COG1280	lysine exporter protein (LysE YggA)
E2P79_06130	COG0826	peptidase U32
E2P79_06140	COG3706	GGDEF domain
E2P79_06150	COG2226	methyltransferase
E2P79_06200	COG0300	oxidoreductase activity
E2P79_06215	COG5002	protein histidine kinase activity
E2P79_06240	COG3142	Participates in the control of copper homeostasis
E2P79_06260	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
E2P79_06265	COG0678	peroxiredoxin activity
E2P79_06275	COG0019	diaminopimelate decarboxylase activity
E2P79_06280	COG1115	amino acid carrier protein
E2P79_06285	COG3706	GGDEF domain
E2P79_06295	COG0534	Mate efflux family protein
E2P79_06305	COG0281	malic enzyme
E2P79_06325	COG0500	methyltransferase
E2P79_06330	COG4106	trans-aconitate 2-methyltransferase activity
E2P79_06335	COG3385	transposase activity
E2P79_06340	COG1801	Protein of unknown function DUF72
E2P79_06350	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
E2P79_06355	COG0217	transcriptional regulatory protein
E2P79_06360	COG1966	Carbon starvation protein
E2P79_06365	COG3279	Response regulator of the LytR AlgR family
E2P79_06370	COG3275	phosphorelay sensor kinase activity
E2P79_06380	COG1454	alcohol dehydrogenase
E2P79_06380	COG1012	belongs to the aldehyde dehydrogenase family
E2P79_06385	COG2095	MarC family integral membrane protein
E2P79_06395	COG0601	transmembrane transport
E2P79_06400	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
E2P79_06415	COG3385	transposase activity
E2P79_06420	COG0861	Integral membrane protein TerC family
E2P79_06425	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
E2P79_06440	COG0840	transmembrane signaling receptor activity
E2P79_06445	COG0840	transmembrane signaling receptor activity
E2P79_06455	COG2971	BadF BadG BcrA BcrD
E2P79_06465	COG4608	Belongs to the ABC transporter superfamily
E2P79_06475	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
E2P79_06480	COG0601	transmembrane transport
E2P79_06515	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
E2P79_06540	COG0436	Aminotransferase
E2P79_06550	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
E2P79_06555	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
E2P79_06560	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
E2P79_06570	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
E2P79_06575	COG0505	Belongs to the CarA family
E2P79_06580	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
E2P79_06590	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
E2P79_06625	COG3220	belongs to the UPF0276 family
E2P79_06660	COG2205	protein histidine kinase activity
E2P79_06665	COG0745	RESPONSE REGULATOR receiver
E2P79_06670	COG0716	FMN binding
E2P79_06690	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
E2P79_06695	COG0033	Phosphoglucomutase
E2P79_06700	COG2194	sulfuric ester hydrolase activity
E2P79_06705	COG4574	serine-type endopeptidase inhibitor activity
E2P79_06725	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
E2P79_06740	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
E2P79_06800	COG2003	Belongs to the UPF0758 family
E2P79_06855	COG3311	Transcriptional regulator
E2P79_06875	COG3501	Rhs element vgr protein
E2P79_06900	COG0582	viral genome integration into host DNA
E2P79_06940	COG4977	sequence-specific DNA binding
E2P79_07090	COG1196	nuclear chromosome segregation
E2P79_07090	COG0739	heme binding
E2P79_07090	COG0741	lytic transglycosylase activity
E2P79_07100	COG2197	response regulator
E2P79_07110	COG0583	DNA-binding transcription factor activity
E2P79_07115	COG3085	chromosome segregation
E2P79_07120	COG1940	carbohydrate kinase activity
E2P79_07120	COG1846	Transcriptional regulator
E2P79_07125	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
E2P79_07130	COG0363	glucosamine-6-phosphate deaminase activity
E2P79_07135	COG1263	PTS System
E2P79_07135	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
E2P79_07135	COG2190	(PTS) system
E2P79_07155	COG0735	belongs to the Fur family
E2P79_07165	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
E2P79_07170	COG1677	Flagellar hook-basal body complex protein FliE
E2P79_07180	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
E2P79_07230	COG1987	bacterial-type flagellum assembly
E2P79_07255	COG0455	bacterial-type flagellum organization
E2P79_07270	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
E2P79_07275	COG2198	Histidine kinase
E2P79_07275	COG0643	Histidine kinase
E2P79_07280	COG2201	protein-glutamate methylesterase activity
E2P79_07285	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
E2P79_07290	COG1360	Flagellar Motor Protein
E2P79_07295	COG1192	Involved in chromosome partitioning
E2P79_07305	COG0835	chemotaxis
E2P79_07320	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
E2P79_07325	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
E2P79_07330	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
E2P79_07335	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
E2P79_07345	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
E2P79_07355	COG4235	cytochrome complex assembly
E2P79_07355	COG3088	subunit of a heme lyase
E2P79_07370	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
E2P79_07415	COG0625	glutathione transferase activity
E2P79_07420	COG3153	acetyltransferase
E2P79_07440	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
E2P79_07455	COG1028	Short-chain dehydrogenase reductase Sdr
E2P79_07460	COG0616	signal peptide processing
E2P79_07465	COG3724	N-succinylarginine dihydrolase activity
E2P79_07470	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
E2P79_07475	COG1301	dicarboxylic acid transport
E2P79_07480	COG2431	L-lysine efflux transmembrane transporter activity
E2P79_07490	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
E2P79_07495	COG4215	(ABC) transporter
E2P79_07510	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
E2P79_07515	COG5001	Diguanylate cyclase
E2P79_07515	COG3300	MHYT domain
E2P79_07525	COG2373	Large extracellular alpha-helical protein
E2P79_07530	COG4953	penicillin-binding protein 1C
E2P79_07545	COG0301	tRNA thio-modification
E2P79_07545	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
E2P79_07550	COG3385	transposase activity
E2P79_07570	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
E2P79_07580	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
E2P79_07585	COG4104	PAAR repeat-containing protein
E2P79_07600	COG3979	chitinase
E2P79_07605	COG0493	'glutamate synthase
E2P79_07615	COG1242	4 iron, 4 sulfur cluster binding
E2P79_07665	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
E2P79_07670	COG2375	cellular response to nickel ion
E2P79_07680	COG1021	2,3-dihydroxybenzoate-AMP ligase
E2P79_07685	COG3433	isochorismatase activity
E2P79_07685	COG1535	isochorismatase
E2P79_07695	COG1028	Short-chain dehydrogenase reductase Sdr
E2P79_07705	COG0318	PFAM AMP-dependent synthetase and ligase
E2P79_07705	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
E2P79_07705	COG3321	synthase
E2P79_07705	COG1028	Short-chain dehydrogenase reductase Sdr
E2P79_07705	COG0300	oxidoreductase activity
E2P79_07710	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
E2P79_07715	COG2977	Belongs to the P-Pant transferase superfamily
E2P79_07720	COG1120	ATPase activity
E2P79_07725	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
E2P79_07730	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
E2P79_07735	COG4771	TonB-dependent receptor
E2P79_07745	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
E2P79_07750	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
E2P79_07760	COG4591	ABC-type transport system involved in lipoprotein release permease component
E2P79_07765	COG1136	(ABC) transporter
E2P79_07770	COG4591	ABC-type transport system involved in lipoprotein release permease component
E2P79_07775	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
E2P79_07785	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
E2P79_07790	COG2894	cell division
E2P79_07795	COG0850	regulation of cytokinetic process
E2P79_07800	COG3100	YcgL domain-containing protein
E2P79_07805	COG2983	Belongs to the UPF0260 family
E2P79_07815	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
E2P79_07825	COG3067	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
E2P79_07830	COG2186	Transcriptional regulator
E2P79_07835	COG2719	SpoVR family
E2P79_07840	COG2718	Belongs to the UPF0229 family
E2P79_07845	COG2766	serine protein kinase
E2P79_07860	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
E2P79_07865	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
E2P79_07870	COG0291	Belongs to the bacterial ribosomal protein bL35 family
E2P79_07875	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
E2P79_07880	COG0488	(ABC) transporter
E2P79_07885	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
E2P79_07890	COG3162	membrane
E2P79_07905	COG1024	Enoyl-CoA hydratase
E2P79_07910	COG1115	amino acid carrier protein
E2P79_07945	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
E2P79_07945	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
E2P79_07960	COG2314	TM2 domain
E2P79_07970	COG0582	viral genome integration into host DNA
E2P79_08010	COG0693	protein deglycase activity
E2P79_08020	COG2801	Transposase and inactivated derivatives
E2P79_08050	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
E2P79_08055	COG2885	chlorophyll binding
E2P79_08060	COG1253	flavin adenine dinucleotide binding
E2P79_08070	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
E2P79_08075	COG0123	including yeast histone deacetylase and acetoin utilization protein
E2P79_08080	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
E2P79_08085	COG1199	ATP-dependent helicase activity
E2P79_08090	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
E2P79_08095	COG0784	Response regulator, receiver
E2P79_08095	COG3437	response regulator, receiver
E2P79_08115	COG1355	regulation of microtubule-based process
E2P79_08130	COG2814	Major facilitator Superfamily
E2P79_08190	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
E2P79_08205	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
E2P79_08220	COG0469	pyruvate kinase activity
E2P79_08225	COG1737	Transcriptional regulator
E2P79_08230	COG0837	glucose binding
E2P79_08235	COG3634	alkyl hydroperoxide reductase activity
E2P79_08240	COG0450	alkyl hydroperoxide reductase
E2P79_08245	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
E2P79_08250	COG4136	ATPase activity
E2P79_08255	COG4135	transport system, permease component
E2P79_08260	COG4134	Bacterial extracellular solute-binding protein
E2P79_08270	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
E2P79_08290	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
E2P79_08305	COG2911	Protein conserved in bacteria
E2P79_08320	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
E2P79_08350	COG1607	acyl-coa hydrolase
E2P79_08365	COG1388	LysM domain
E2P79_08365	COG0741	lytic transglycosylase activity
E2P79_08370	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
E2P79_08375	COG2226	methyltransferase
E2P79_08380	COG0328	RNA-DNA hybrid ribonuclease activity
E2P79_08385	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
E2P79_08400	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
E2P79_08405	COG0121	glutamine amidotransferase
E2P79_08410	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
E2P79_08415	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
E2P79_08420	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
E2P79_08440	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
E2P79_08445	COG0483	inositol monophosphate 1-phosphatase activity
E2P79_08450	COG2814	Major facilitator Superfamily
E2P79_08460	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
E2P79_08470	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
E2P79_08475	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
E2P79_08480	COG0404	The glycine cleavage system catalyzes the degradation of glycine
E2P79_08485	COG0509	glycine decarboxylation via glycine cleavage system
E2P79_08490	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
E2P79_08490	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
E2P79_08505	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
E2P79_08510	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
E2P79_08515	COG2089	acid synthase
E2P79_08530	COG0673	inositol 2-dehydrogenase activity
E2P79_08535	COG1083	cytidylyl-transferase
E2P79_08540	COG1028	Short-chain dehydrogenase reductase Sdr
E2P79_08580	COG0367	asparagine synthase
E2P79_08610	COG1091	dTDP-4-dehydrorhamnose reductase activity
E2P79_08625	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
E2P79_08635	COG3132	Protein of unknown function, DUF480
E2P79_08645	COG3852	Histidine kinase
E2P79_08650	COG2204	response regulator
E2P79_08655	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
E2P79_08675	COG0784	Response regulator, receiver
E2P79_08675	COG2198	Histidine kinase
E2P79_08675	COG5002	protein histidine kinase activity
E2P79_08685	COG2197	response regulator
E2P79_08695	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
E2P79_08710	COG0243	molybdopterin cofactor binding
E2P79_08715	COG0437	4 iron, 4 sulfur cluster binding
E2P79_08720	COG0348	domain, Protein
E2P79_08730	COG3005	denitrification pathway
E2P79_08735	COG0521	Mo-molybdopterin cofactor biosynthetic process
E2P79_08740	COG0315	cyclic pyranopterin monophosphate synthase activity
E2P79_08745	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
E2P79_08750	COG0314	molybdopterin synthase activity
E2P79_08765	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
E2P79_08770	COG2267	carboxylic ester hydrolase activity
E2P79_08780	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
E2P79_08785	COG0303	'Molybdopterin
E2P79_08790	COG0302	gtp cyclohydrolase
E2P79_08795	COG0840	transmembrane signaling receptor activity
E2P79_08800	COG2759	Belongs to the formate--tetrahydrofolate ligase family
E2P79_08810	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
E2P79_08835	COG1609	Transcriptional regulator
E2P79_08840	COG1263	PTS System
E2P79_08840	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
E2P79_08860	COG4792	protein secretion
E2P79_08865	COG4791	protein targeting
E2P79_08870	COG4794	Type iii secretion
E2P79_08875	COG4790	Type iii secretion
E2P79_08880	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
E2P79_08920	COG0457	Tetratricopeptide repeat
E2P79_09045	COG3135	benzoate transporter
E2P79_09050	COG1396	sequence-specific DNA binding
E2P79_09110	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
E2P79_09120	COG3770	Murein endopeptidase that cleaves the D-alanyl-meso-2,6- diamino-pimelyl amide bond that connects peptidoglycan strands. Likely plays a role in the removal of murein from the sacculus
E2P79_09130	COG0724	RNA recognition motif
E2P79_09135	COG4989	oxidoreductase activity
E2P79_09160	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
E2P79_09185	COG2979	Protein of unknown function (DUF533)
E2P79_09205	COG1595	DNA-templated transcription, initiation
E2P79_09225	COG1271	oxidase subunit
E2P79_09230	COG1294	oxidase, subunit
E2P79_09250	COG3220	belongs to the UPF0276 family
E2P79_09265	COG2249	NAD(P)H dehydrogenase (quinone) activity
E2P79_09275	COG0733	neurotransmitter:sodium symporter activity
E2P79_09285	COG1595	DNA-templated transcription, initiation
E2P79_09315	COG0714	Associated with various cellular activities
E2P79_09320	COG0183	Belongs to the thiolase family
E2P79_09325	COG1250	3-hydroxyacyl-CoA dehydrogenase
E2P79_09325	COG1024	Enoyl-CoA hydratase
E2P79_09335	COG4681	YaeQ
E2P79_09350	COG0586	Pfam SNARE associated Golgi protein
E2P79_09355	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
E2P79_09360	COG0583	DNA-binding transcription factor activity
E2P79_09365	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
E2P79_09385	COG0583	DNA-binding transcription factor activity
E2P79_09400	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
E2P79_09405	COG0574	Belongs to the PEP-utilizing enzyme family
E2P79_09405	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
E2P79_09410	COG1404	Belongs to the peptidase S8 family
E2P79_09415	COG2824	Alkylphosphonate utilization operon protein PhnA
E2P79_09430	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
E2P79_09440	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
E2P79_09460	COG3755	Protein conserved in bacteria
E2P79_09480	COG0861	Integral membrane protein TerC family
E2P79_09510	COG2119	membrane
E2P79_09515	COG0023	Translation Initiation Factor
E2P79_09555	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
E2P79_09560	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
E2P79_09565	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
E2P79_09570	COG0544	peptidyl-prolyl cis-trans isomerase activity
E2P79_09575	COG0740	serine-type endopeptidase activity
E2P79_09580	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
E2P79_09585	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
E2P79_09590	COG0776	regulation of translation
E2P79_09595	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
E2P79_09600	COG4166	transmembrane transport
E2P79_09605	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
E2P79_09625	COG0814	amino acid
E2P79_09630	COG1609	Transcriptional regulator
E2P79_09640	COG1105	Belongs to the carbohydrate kinase PfkB family
E2P79_09645	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
E2P79_09645	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
E2P79_09645	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
E2P79_09650	COG3313	Fe-S protein
E2P79_09655	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
E2P79_09675	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
E2P79_09700	COG0205	6-phosphofructokinase activity
E2P79_09710	COG1434	Gram-negative-bacterium-type cell wall biogenesis
E2P79_09715	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
E2P79_09725	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
E2P79_09735	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
E2P79_09745	COG3385	transposase activity
E2P79_09755	COG0537	adenosine 5'-monophosphoramidase activity
E2P79_09760	COG3417	Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1B (PBP1b)
E2P79_09785	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
E2P79_09795	COG2354	Protein conserved in bacteria
E2P79_09815	COG1252	NADH dehydrogenase
E2P79_09820	COG0393	Putative heavy-metal-binding
E2P79_09825	COG1619	proteins homologs of microcin C7 resistance protein MccF
E2P79_09830	COG0604	alcohol dehydrogenase
E2P79_09845	COG2009	succinate dehydrogenase
E2P79_09850	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
E2P79_09870	COG0508	dehydrogenase complex catalyzes the overall conversion of
E2P79_09875	COG0045	succinate-CoA ligase (ADP-forming) activity
E2P79_09890	COG2015	COG2015, Alkyl sulfatase and related hydrolases
E2P79_09895	COG0840	transmembrane signaling receptor activity
E2P79_09905	COG1760	l-serine dehydratase
E2P79_09915	COG1451	nucleotide metabolic process
E2P79_09930	COG3069	C4-dicarboxylate transmembrane transporter activity
E2P79_09940	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
E2P79_09940	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
E2P79_09945	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
E2P79_09955	COG3385	transposase activity
E2P79_09960	COG3123	guanosine phosphorylase activity
E2P79_09965	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
E2P79_09970	COG0840	transmembrane signaling receptor activity
E2P79_09975	COG1254	Belongs to the acylphosphatase family
E2P79_09985	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
E2P79_09985	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
E2P79_09995	COG0572	uridine kinase
E2P79_10000	COG0717	Belongs to the dCTP deaminase family
E2P79_10005	COG0306	phosphate transporter
E2P79_10010	COG1530	ribonuclease E activity
E2P79_10015	COG0564	pseudouridine synthase activity
E2P79_10020	COG3397	chitin binding
E2P79_10030	COG1399	metal-binding, possibly nucleic acid-binding protein
E2P79_10035	COG0333	Belongs to the bacterial ribosomal protein bL32 family
E2P79_10040	COG0416	fatty acid biosynthetic process
E2P79_10045	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
E2P79_10055	COG1028	Short-chain dehydrogenase reductase Sdr
E2P79_10060	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
E2P79_10065	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
E2P79_10070	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
E2P79_10075	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
E2P79_10080	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
E2P79_10085	COG0470	DNA polymerase III
E2P79_10090	COG0084	hydrolase, TatD family'
E2P79_10100	COG1228	amidohydrolase
E2P79_10120	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
E2P79_10120	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
E2P79_10130	COG3008	intermembrane lipid transfer
E2P79_10135	COG2995	paraquat-inducible protein a
E2P79_10145	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
E2P79_10150	COG0372	Belongs to the citrate synthase family
E2P79_10190	COG1309	transcriptional regulator
E2P79_10210	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
E2P79_10215	COG0745	RESPONSE REGULATOR receiver
E2P79_10240	COG1366	Belongs to the anti-sigma-factor antagonist family
E2P79_10250	COG2205	protein histidine kinase activity
E2P79_10250	COG3437	response regulator, receiver
E2P79_10250	COG3850	Histidine kinase
E2P79_10250	COG4999	Histidine kinase
E2P79_10255	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
E2P79_10265	COG0297	glycogen (starch) synthase activity
E2P79_10305	COG0438	transferase activity, transferring glycosyl groups
E2P79_10310	COG0110	maltose O-acetyltransferase activity
E2P79_10330	COG0438	transferase activity, transferring glycosyl groups
E2P79_10340	COG3141	response to X-ray
E2P79_10365	COG4128	Pfam Zonular occludens toxin
E2P79_10410	COG1067	ATP-dependent peptidase activity
E2P79_10415	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
E2P79_10425	COG0488	(ABC) transporter
E2P79_10435	COG0116	Belongs to the methyltransferase superfamily
E2P79_10435	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
E2P79_10445	COG0167	dihydroorotate dehydrogenase activity
E2P79_10450	COG2902	Dehydrogenase
E2P79_10460	COG0308	aminopeptidase N
E2P79_10480	COG1132	(ABC) transporter
E2P79_10485	COG1132	(ABC) transporter
E2P79_10490	COG3437	response regulator, receiver
E2P79_10490	COG3850	Histidine kinase
E2P79_10490	COG4999	Histidine kinase
E2P79_10490	COG2205	protein histidine kinase activity
E2P79_10495	COG3118	belongs to the thioredoxin family
E2P79_10500	COG0471	metal ion transport
E2P79_10515	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
E2P79_10560	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
E2P79_10565	COG0697	spore germination
E2P79_10570	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
E2P79_10575	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
E2P79_10590	COG0307	riboflavin synthase, alpha
E2P79_10600	COG0534	Mate efflux family protein
E2P79_10645	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
E2P79_10650	COG2925	Exonuclease
E2P79_10660	COG3345	alpha-galactosidase
E2P79_10665	COG1380	Effector of murein hydrolase LrgA
E2P79_10670	COG1346	cytolysis
E2P79_10675	COG0295	cytidine deaminase activity
E2P79_10690	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
E2P79_10700	COG1869	D-ribose catabolic process
E2P79_10705	COG1129	ABC transporter
E2P79_10710	COG1172	Belongs to the binding-protein-dependent transport system permease family
E2P79_10715	COG1879	ABC-type sugar transport system periplasmic component
E2P79_10720	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
E2P79_10730	COG2199	diguanylate cyclase activity
E2P79_10740	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
E2P79_10755	COG2205	protein histidine kinase activity
E2P79_10755	COG0784	Response regulator, receiver
E2P79_10760	COG0784	Response regulator, receiver
E2P79_10760	COG2205	protein histidine kinase activity
E2P79_10765	COG0776	regulation of translation
E2P79_10770	COG0072	phenylalanine-tRNA ligase activity
E2P79_10770	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
E2P79_10775	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
E2P79_10785	COG0058	SHG alpha-glucan phosphorylase activity
E2P79_10800	COG2067	long-chain fatty acid transport protein
E2P79_10805	COG2067	long-chain fatty acid transport protein
E2P79_10810	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
E2P79_10830	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
E2P79_10840	COG2062	phosphohistidine phosphatase, SixA
E2P79_10875	COG1537	nuclear-transcribed mRNA catabolic process, no-go decay
E2P79_10880	COG1196	nuclear chromosome segregation
E2P79_10945	COG0210	DNA helicase
E2P79_10950	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
E2P79_10955	COG0582	viral genome integration into host DNA
E2P79_10965	COG0519	Catalyzes the synthesis of GMP from XMP
E2P79_10965	COG0518	GMP synthase (glutamine-hydrolyzing) activity
E2P79_10970	COG0516	GMP reductase activity
E2P79_10970	COG0517	IMP dehydrogenase activity
E2P79_11005	COG0494	nUDIX hydrolase
E2P79_11010	COG0814	amino acid
E2P79_11015	COG1760	l-serine dehydratase
E2P79_11055	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
E2P79_11070	COG0516	GMP reductase activity
E2P79_11070	COG0517	IMP dehydrogenase activity
E2P79_11080	COG1473	amidohydrolase
E2P79_11090	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
E2P79_11135	COG3593	DNA synthesis involved in DNA repair
E2P79_11155	COG0730	response to heat
E2P79_11170	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
E2P79_11175	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
E2P79_11180	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
E2P79_11190	COG0793	Belongs to the peptidase S41A family
E2P79_11195	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
E2P79_11200	COG1956	GAF domain-containing protein
E2P79_11210	COG3278	Belongs to the heme-copper respiratory oxidase family
E2P79_11225	COG2010	Cytochrome c
E2P79_11250	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
E2P79_11255	COG0589	response to stress
E2P79_11260	COG0037	tRNA processing
E2P79_11280	COG1176	ABC-type spermidine putrescine transport system, permease component I
E2P79_11285	COG1177	transmembrane transport
E2P79_11290	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
E2P79_11295	COG3385	transposase activity
E2P79_11300	COG1181	Belongs to the D-alanine--D-alanine ligase family
E2P79_11310	COG0386	Belongs to the glutathione peroxidase family
E2P79_11325	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
E2P79_11330	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
E2P79_11335	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
E2P79_11355	COG0598	Magnesium transport protein CorA
E2P79_11370	COG0556	nucleotide-excision repair
E2P79_11380	COG0513	Belongs to the DEAD box helicase family
E2P79_11390	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
E2P79_11395	COG2890	protein-(glutamine-N5) methyltransferase activity
E2P79_11400	COG2840	Smr protein MutS2
E2P79_11405	COG3706	GGDEF domain
E2P79_11430	COG2985	domain, Protein
E2P79_11430	COG0569	domain protein
E2P79_11435	COG1022	Amp-dependent synthetase and ligase
E2P79_11450	COG1166	arginine decarboxylase activity
E2P79_11465	COG2885	chlorophyll binding
E2P79_11470	COG3706	GGDEF domain
E2P79_11485	COG2154	pterin-4-alpha-carbinolamine dehydratase
E2P79_11495	COG3768	UPF0283 membrane protein
E2P79_11500	COG3106	COG3106 Predicted ATPase
E2P79_11515	COG1842	Phage shock protein A
E2P79_11520	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
E2P79_11525	COG4166	transmembrane transport
E2P79_11530	COG4168	peptide transport system, permease
E2P79_11535	COG4171	peptide transport system, permease
E2P79_11545	COG4172	Belongs to the ABC transporter superfamily
E2P79_11555	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
E2P79_11560	COG1286	toxin biosynthetic process
E2P79_11565	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
E2P79_11570	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
E2P79_11575	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
E2P79_11580	COG1674	ftsk spoiiie
E2P79_11580	COG0531	amino acid
E2P79_11590	COG0686	Belongs to the AlaDH PNT family
E2P79_11595	COG0840	transmembrane signaling receptor activity
E2P79_11610	COG2723	6-phospho-beta-galactosidase activity
E2P79_11615	COG0583	DNA-binding transcription factor activity
E2P79_11625	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
E2P79_11635	COG0004	ammonium transporteR
E2P79_11680	COG0322	excinuclease ABC activity
E2P79_11685	COG2197	response regulator
E2P79_11690	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
E2P79_11695	COG2835	tetraacyldisaccharide 4'-kinase activity
E2P79_11700	COG1663	tetraacyldisaccharide 4'-kinase activity
E2P79_11705	COG1132	(ABC) transporter
E2P79_11725	COG0670	Belongs to the BI1 family
E2P79_11730	COG1289	transmembrane transporter activity
E2P79_11735	COG2920	part of a sulfur-relay system
E2P79_11740	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
E2P79_11745	COG0285	dihydrofolate synthase activity
E2P79_11750	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
E2P79_11755	COG0101	tRNA pseudouridine synthase activity
E2P79_11765	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
E2P79_11770	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
E2P79_11775	COG0671	phosphoesterase, PA-phosphatase related
E2P79_11780	COG0492	ferredoxin-NADP+ reductase activity
E2P79_11785	COG3706	GGDEF domain
E2P79_11790	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
E2P79_11795	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
E2P79_11800	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
E2P79_11805	COG0542	response to heat
E2P79_11810	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
E2P79_11815	COG1278	Cold shock
E2P79_11825	COG3134	Outer membrane lipoprotein
E2P79_11835	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
E2P79_11845	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
E2P79_11845	COG4651	solute:proton antiporter activity
E2P79_11855	COG0367	asparagine synthase
E2P79_11865	COG0642	Histidine kinase
E2P79_11910	COG4657	Part of a membrane complex involved in electron transport
E2P79_11915	COG2878	Part of a membrane complex involved in electron transport
E2P79_11925	COG4658	electron transport chain
E2P79_11940	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
E2P79_11945	COG0346	lactoylglutathione lyase activity
E2P79_11960	COG0704	Plays a role in the regulation of phosphate uptake
E2P79_11965	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
E2P79_12040	COG0732	type I restriction modification DNA specificity domain
E2P79_12045	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
E2P79_12070	COG1785	Belongs to the alkaline phosphatase family
E2P79_12090	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
E2P79_12095	COG2197	response regulator
E2P79_12130	COG2050	protein possibly involved in aromatic compounds catabolism
E2P79_12150	COG3568	Endonuclease Exonuclease Phosphatase
E2P79_12165	COG0583	DNA-binding transcription factor activity
E2P79_12170	COG1566	PFAM secretion protein HlyD family protein
E2P79_12180	COG3214	Protein conserved in bacteria
E2P79_12200	COG1028	Short-chain dehydrogenase reductase Sdr
E2P79_12210	COG1024	Enoyl-CoA hydratase
E2P79_12215	COG1024	Enoyl-CoA hydratase
E2P79_12220	COG1960	acyl-CoA dehydrogenase activity
E2P79_12230	COG1960	acyl-CoA dehydrogenase activity
E2P79_12235	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
E2P79_12270	COG1584	GPR1 FUN34 yaaH family protein
E2P79_12275	COG3385	transposase activity
E2P79_12280	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
E2P79_12290	COG1944	ATP diphosphatase activity
E2P79_12295	COG2116	formate transmembrane transporter activity
E2P79_12300	COG1882	Formate acetyltransferase
E2P79_12345	COG5002	protein histidine kinase activity
E2P79_12350	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
E2P79_12370	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
E2P79_12380	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
E2P79_12380	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
E2P79_12385	COG0527	aspartate kinase activity
E2P79_12395	COG3012	SEC-C Motif Domain Protein
E2P79_12405	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
E2P79_12410	COG3075	Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses fumarate or nitrate as electron acceptor
E2P79_12415	COG0247	lactate metabolic process
E2P79_12430	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
E2P79_12435	COG0437	4 iron, 4 sulfur cluster binding
E2P79_12440	COG3301	Polysulphide reductase, NrfD
E2P79_12450	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
E2P79_12455	COG4235	cytochrome complex assembly
E2P79_12455	COG3088	subunit of a heme lyase
E2P79_12470	COG0417	DNA replication proofreading
E2P79_12475	COG2199	diguanylate cyclase activity
E2P79_12475	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
E2P79_12495	COG0840	transmembrane signaling receptor activity
E2P79_12500	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
E2P79_12510	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
E2P79_12515	COG0563	adenylate kinase activity
E2P79_12520	COG0326	Molecular chaperone. Has ATPase activity
E2P79_12525	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
E2P79_12535	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
E2P79_12540	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
E2P79_12545	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
E2P79_12550	COG2832	Protein of unknown function (DUF454)
E2P79_12555	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
E2P79_12570	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
E2P79_12575	COG0318	PFAM AMP-dependent synthetase and ligase
E2P79_12580	COG1073	alpha beta
E2P79_12580	COG2226	methyltransferase
E2P79_12585	COG3065	identical protein binding
E2P79_12590	COG1214	PFAM Peptidase M22, glycoprotease
E2P79_12595	COG1199	ATP-dependent helicase activity
E2P79_12605	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
E2P79_12610	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
E2P79_12615	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
E2P79_12620	COG0131	Imidazoleglycerol-phosphate dehydratase
E2P79_12620	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
E2P79_12625	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
E2P79_12630	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
E2P79_12635	COG0107	imidazoleglycerol-phosphate synthase activity
E2P79_12640	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
E2P79_12640	COG0140	phosphoribosyl-ATP diphosphatase activity
E2P79_12650	COG2951	lytic endotransglycosylase activity
E2P79_12665	COG1757	Na H antiporter
E2P79_12670	COG2916	Histone family protein nucleoid-structuring protein H-NS
E2P79_12675	COG2096	Adenosyltransferase
E2P79_12680	COG3530	Putative quorum-sensing-regulated virulence factor
E2P79_12685	COG0602	queuosine metabolic process
E2P79_12690	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
E2P79_12705	COG0284	orotidine-5'-phosphate decarboxylase activity
E2P79_12710	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
E2P79_12715	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
E2P79_12720	COG0776	regulation of translation
E2P79_12725	COG0539	negative regulation of cytoplasmic translation
E2P79_12730	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
E2P79_12735	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
E2P79_12740	COG0583	DNA-binding transcription factor activity
E2P79_12745	COG2814	Major facilitator Superfamily
E2P79_12765	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
E2P79_12780	COG0583	DNA-binding transcription factor activity
E2P79_12785	COG3437	response regulator, receiver
E2P79_12800	COG0625	glutathione transferase activity
E2P79_12810	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
E2P79_12825	COG0564	pseudouridine synthase activity
E2P79_12835	COG1448	Aminotransferase
E2P79_12850	COG1393	Belongs to the ArsC family
E2P79_12855	COG0798	PFAM Bile acid sodium symporter
E2P79_12875	COG0659	secondary active sulfate transmembrane transporter activity
E2P79_12885	COG0538	isocitrate dehydrogenase activity
E2P79_12900	COG0482	sulfurtransferase activity
E2P79_12905	COG2915	High frequency lysogenization protein hflD homolog
E2P79_12910	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
E2P79_12915	COG2850	peptidyl-arginine hydroxylation
E2P79_12935	COG1605	Chorismate mutase
E2P79_12935	COG0287	Prephenate dehydrogenase
E2P79_12940	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
E2P79_12945	COG0584	glycerophosphoryl diester phosphodiesterase
E2P79_12950	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
E2P79_12955	COG1349	DNA-binding transcription factor activity
E2P79_12960	COG2271	Major facilitator Superfamily
E2P79_12965	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
E2P79_12980	COG2716	regulation of RNA biosynthetic process
E2P79_12985	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
E2P79_12995	COG2239	Acts as a magnesium transporter
E2P79_13000	COG1086	Polysaccharide biosynthesis protein
E2P79_13005	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
E2P79_13055	COG0318	PFAM AMP-dependent synthetase and ligase
E2P79_13060	COG1028	Short-chain dehydrogenase reductase Sdr
E2P79_13075	COG1083	cytidylyl-transferase
E2P79_13125	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
E2P79_13130	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
E2P79_13145	COG1705	Flagellar rod assembly protein muramidase FlgJ
E2P79_13145	COG3951	Flagellar rod assembly protein muramidase FlgJ
E2P79_13150	COG1706	bacterial-type flagellum-dependent cell motility
E2P79_13155	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
E2P79_13160	COG4786	Flagellar basal body rod
E2P79_13165	COG4787	bacterial-type flagellum-dependent cell motility
E2P79_13180	COG1558	bacterial-type flagellum-dependent cell motility
E2P79_13185	COG1815	bacterial-type flagellum-dependent cell motility
E2P79_13195	COG0835	chemotaxis
E2P79_13195	COG0784	Response regulator, receiver
E2P79_13200	COG1261	Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly
E2P79_13215	COG0622	Phosphoesterase
E2P79_13230	COG1187	pseudouridine synthase activity
E2P79_13245	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
E2P79_13250	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
E2P79_13285	COG1278	Cold shock
E2P79_13300	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
E2P79_13325	COG0590	tRNA wobble adenosine to inosine editing
E2P79_13355	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
E2P79_13395	COG1061	Type III restriction enzyme res subunit
E2P79_13400	COG2027	D-alanyl-D-alanine carboxypeptidase
E2P79_13405	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
E2P79_13410	COG1645	bacterial-type flagellum-dependent swarming motility
E2P79_13415	COG1160	GTP binding
E2P79_13420	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
E2P79_13425	COG2976	Protein conserved in bacteria
E2P79_13430	COG0124	histidyl-tRNA synthetase
E2P79_13435	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
E2P79_13440	COG1426	Protein conserved in bacteria
E2P79_13450	COG0820	rRNA (adenine-C2-)-methyltransferase activity
E2P79_13455	COG0105	UTP biosynthetic process
E2P79_13465	COG1393	Belongs to the ArsC family
E2P79_13470	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
E2P79_13475	COG1876	peptidase activity
E2P79_13485	COG0450	alkyl hydroperoxide reductase
E2P79_13490	COG0583	DNA-binding transcription factor activity
E2P79_13495	COG2233	PERMEase
E2P79_13510	COG0281	malic enzyme
E2P79_13550	COG1032	radical SAM domain protein
E2P79_13570	COG1752	Esterase of the alpha-beta hydrolase superfamily
E2P79_13575	COG0531	amino acid
E2P79_13605	COG3263	regulation of cellular component size
E2P79_13610	COG3525	Glycosyl hydrolase, family 20, catalytic domain
E2P79_13620	COG1280	lysine exporter protein (LysE YggA)
E2P79_13645	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
E2P79_13665	COG0708	Exodeoxyribonuclease III
E2P79_13675	COG1881	PFAM PEBP family protein
E2P79_13685	COG3408	Glycogen debranching enzyme
E2P79_13685	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
E2P79_13715	COG0437	4 iron, 4 sulfur cluster binding
E2P79_13720	COG3383	formate dehydrogenase (NAD+) activity
E2P79_13720	COG0243	molybdopterin cofactor binding
E2P79_13755	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
E2P79_13765	COG3852	Histidine kinase
E2P79_13780	COG4662	Binding-protein-dependent transport system inner membrane component
E2P79_13795	COG0303	'Molybdopterin
E2P79_13815	COG0791	NLP P60 protein
E2P79_13820	COG2091	lysine biosynthetic process via aminoadipic acid
E2P79_13835	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
E2P79_13840	COG0788	formyltetrahydrofolate deformylase activity
E2P79_13865	COG3384	dioxygenase
E2P79_13870	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
E2P79_13885	COG1136	(ABC) transporter
E2P79_13885	COG0577	efflux transmembrane transporter activity
E2P79_13890	COG0577	efflux transmembrane transporter activity
E2P79_13890	COG1136	(ABC) transporter
E2P79_13895	COG0577	efflux transmembrane transporter activity
E2P79_13895	COG1136	(ABC) transporter
E2P79_13900	COG1566	PFAM secretion protein HlyD family protein
E2P79_13945	COG0443	Heat shock 70 kDa protein
E2P79_13950	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
E2P79_13955	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
E2P79_14005	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
E2P79_14010	COG1454	alcohol dehydrogenase
E2P79_14015	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
E2P79_14025	COG2914	Belongs to the UPF0125 (RnfH) family
E2P79_14030	COG2867	negative regulation of translational initiation
E2P79_14035	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
E2P79_14045	COG1715	Restriction endonuclease
E2P79_14050	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
E2P79_14060	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
E2P79_14090	COG3383	formate dehydrogenase (NAD+) activity
E2P79_14100	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
E2P79_14120	COG2080	2 iron, 2 sulfur cluster binding
E2P79_14125	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
E2P79_14130	COG1529	Aldehyde oxidase and xanthine dehydrogenase
E2P79_14135	COG2252	PERMEase
E2P79_14140	COG0402	S-adenosylhomocysteine deaminase activity
E2P79_14150	COG2080	2 iron, 2 sulfur cluster binding
E2P79_14150	COG1529	Aldehyde oxidase and xanthine dehydrogenase
E2P79_14155	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
E2P79_14160	COG0402	S-adenosylhomocysteine deaminase activity
E2P79_14165	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
E2P79_14165	COG0493	'glutamate synthase
E2P79_14175	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
E2P79_14185	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
E2P79_14210	COG1388	LysM domain
E2P79_14210	COG3103	Sh3 type 3 domain protein
E2P79_14210	COG0791	NLP P60 protein
E2P79_14230	COG0697	spore germination
E2P79_14235	COG0549	Belongs to the carbamate kinase family
E2P79_14245	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
E2P79_14250	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
E2P79_14255	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
E2P79_14285	COG1518	maintenance of DNA repeat elements
E2P79_14295	COG0814	amino acid
E2P79_14300	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
E2P79_14305	COG1982	Orn Lys Arg decarboxylase major
E2P79_14310	COG0531	amino acid
E2P79_14315	COG3710	Transcriptional regulator
E2P79_14320	COG0583	DNA-binding transcription factor activity
E2P79_14330	COG0825	malonyl-CoA metabolic process
E2P79_14335	COG0587	DNA-directed DNA polymerase activity
E2P79_14340	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
E2P79_14345	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
E2P79_14350	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
E2P79_14355	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
E2P79_14360	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
E2P79_14375	COG0750	zinc metalloprotease
E2P79_14380	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
E2P79_14385	COG0575	Belongs to the CDS family
E2P79_14395	COG0233	cytoplasmic translational termination
E2P79_14400	COG0528	UMP kinase activity
E2P79_14405	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
E2P79_14410	COG0052	Belongs to the universal ribosomal protein uS2 family
E2P79_14425	COG2171	N-acyltransferase activity
E2P79_14435	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
E2P79_14435	COG1263	PTS System
E2P79_14470	COG0419	ATPase involved in DNA repair
E2P79_14475	COG0420	3'-5' exonuclease activity
E2P79_14485	COG2974	May be involved in recombination
E2P79_14490	COG4651	solute:proton antiporter activity
E2P79_14490	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
E2P79_14510	COG3437	response regulator, receiver
E2P79_14525	COG2172	sigma factor antagonist activity
E2P79_14535	COG1366	Belongs to the anti-sigma-factor antagonist family
E2P79_14540	COG0583	DNA-binding transcription factor activity
E2P79_14560	COG0583	DNA-binding transcription factor activity
E2P79_14565	COG1028	Short-chain dehydrogenase reductase Sdr
E2P79_14585	COG0813	purine-nucleoside phosphorylase activity
E2P79_14605	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
E2P79_14610	COG0083	homoserine kinase activity
E2P79_14620	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
E2P79_14630	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
E2P79_14640	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
E2P79_14645	COG0511	ligase activity, forming carbon-carbon bonds
E2P79_14650	COG0439	Biotin carboxylase
E2P79_14655	COG3924	membrane
E2P79_14665	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
E2P79_14665	COG1263	PTS System
E2P79_14665	COG2190	(PTS) system
E2P79_14690	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
E2P79_14700	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
E2P79_14705	COG3366	ferrous iron transmembrane transporter activity
E2P79_14710	COG0700	Nucleoside recognition
E2P79_14745	COG0842	Transport permease protein
E2P79_14750	COG1131	(ABC) transporter
E2P79_14770	COG2863	cytochrome
E2P79_14790	COG0163	prenyltransferase activity
E2P79_14795	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
E2P79_14800	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
E2P79_14815	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
E2P79_14835	COG0577	efflux transmembrane transporter activity
E2P79_14850	COG1560	Kdo2-lipid A biosynthetic process
E2P79_14855	COG5433	transposase activity
E2P79_14935	COG0529	Catalyzes the synthesis of activated sulfate
E2P79_14940	COG3273	potassium ion transport
E2P79_14940	COG0471	metal ion transport
E2P79_14945	COG2895	sulfate adenylyltransferase (ATP) activity
E2P79_14950	COG0175	sulfate reduction
E2P79_14955	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
E2P79_14955	COG1648	precorrin-2 dehydrogenase activity
E2P79_14965	COG2146	nitrite reductase [NAD(P)H] activity
E2P79_14965	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
E2P79_14970	COG1116	anion transmembrane transporter activity
E2P79_14975	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
E2P79_14980	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
E2P79_14980	COG1116	anion transmembrane transporter activity
E2P79_14995	COG0330	HflC and HflK could
E2P79_15000	COG1585	Membrane protein implicated in regulation of membrane protease activity
E2P79_15010	COG0488	(ABC) transporter
E2P79_15020	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
E2P79_15070	COG1288	antiporter activity
E2P79_15095	COG0668	transmembrane transport
E2P79_15145	COG0346	lactoylglutathione lyase activity
E2P79_15160	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
E2P79_15175	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
E2P79_15180	COG1335	isochorismatase
E2P79_15185	COG0583	DNA-binding transcription factor activity
E2P79_15195	COG4269	membrane
E2P79_15215	COG2814	Major facilitator Superfamily
E2P79_15220	COG0109	protoheme IX farnesyltransferase activity
E2P79_15225	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
E2P79_15230	COG1845	cytochrome c oxidase, subunit III
E2P79_15235	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
E2P79_15240	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
E2P79_15255	COG3241	Transfers electrons from cytochrome c551 to cytochrome oxidase
E2P79_15260	COG0840	transmembrane signaling receptor activity
E2P79_15265	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
E2P79_15270	COG2211	Major facilitator Superfamily
E2P79_15305	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
E2P79_15320	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
E2P79_15340	COG0671	phosphoesterase, PA-phosphatase related
E2P79_15350	COG3437	response regulator, receiver
E2P79_15350	COG0784	Response regulator, receiver
E2P79_15355	COG0346	lactoylglutathione lyase activity
E2P79_15360	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
E2P79_15375	COG1489	DNA binding
E2P79_15380	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
E2P79_15385	COG2264	protein methyltransferase activity
E2P79_15410	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
E2P79_15425	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
E2P79_15440	COG1139	Iron-sulfur cluster binding protein
E2P79_15445	COG0247	lactate metabolic process
E2P79_15450	COG1620	l-lactate permease
E2P79_15455	COG0583	DNA-binding transcription factor activity
E2P79_15500	COG0316	Belongs to the HesB IscA family
E2P79_15515	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
E2P79_15525	COG3591	Belongs to the peptidase S1B family
E2P79_15535	COG1946	Acyl-CoA thioesterase
E2P79_15540	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
E2P79_15555	COG1522	sequence-specific DNA binding
E2P79_15560	COG0778	Nitroreductase
E2P79_15565	COG1902	pentaerythritol trinitrate reductase activity
E2P79_15565	COG0446	pyridine nucleotide-disulphide oxidoreductase
E2P79_15570	COG0616	signal peptide processing
E2P79_15575	COG0786	glutamate:sodium symporter activity
E2P79_15580	COG0252	asparaginase activity
E2P79_15585	COG3139	Protein of unknown function (DUF1315)
E2P79_15600	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
E2P79_15610	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
E2P79_15615	COG1640	4-alpha-glucanotransferase
E2P79_15620	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
E2P79_15630	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
E2P79_15700	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
E2P79_15705	COG2885	chlorophyll binding
E2P79_15710	COG0823	Involved in the tonB-independent uptake of proteins
E2P79_15725	COG0811	peptide transport
E2P79_15730	COG0824	Thioesterase
E2P79_15735	COG3790	cyd operon protein YbgE
E2P79_15740	COG4890	Cyd operon protein YbgT
E2P79_15745	COG1294	oxidase, subunit
E2P79_15755	COG2255	four-way junction helicase activity
E2P79_15760	COG0632	four-way junction helicase activity
E2P79_15770	COG0442	prolyl-tRNA aminoacylation
E2P79_15775	COG3397	chitin binding
E2P79_15800	COG3655	Transcriptional regulator
E2P79_15815	COG4771	TonB-dependent receptor
E2P79_15835	COG0748	coenzyme F420 binding
E2P79_15850	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
E2P79_15875	COG0741	lytic transglycosylase activity
E2P79_15880	COG2233	PERMEase
E2P79_15885	COG0488	(ABC) transporter
E2P79_15895	COG2252	PERMEase
E2P79_15905	COG0521	Mo-molybdopterin cofactor biosynthetic process
E2P79_15925	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
E2P79_15930	COG1028	Short-chain dehydrogenase reductase Sdr
E2P79_15965	COG2986	histidine ammonia-lyase
E2P79_15975	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
E2P79_15980	COG0318	PFAM AMP-dependent synthetase and ligase
E2P79_15990	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
E2P79_15995	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
E2P79_16025	COG2313	pseudouridylate synthase activity
E2P79_16040	COG0589	response to stress
E2P79_16045	COG2204	response regulator
E2P79_16065	COG0737	Belongs to the 5'-nucleotidase family
E2P79_16075	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
E2P79_16095	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
E2P79_16100	COG2195	Cleaves the N-terminal amino acid of tripeptides
E2P79_16105	COG0602	queuosine metabolic process
E2P79_16110	COG1328	CTP reductase activity
E2P79_16120	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
E2P79_16140	COG2860	membrane
E2P79_16155	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
E2P79_16160	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
E2P79_16165	COG1702	phosphate starvation-inducible protein PhoH
E2P79_16170	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
E2P79_16175	COG4535	Mg2 and Co2 transporter CorC
E2P79_16180	COG0815	Transfers the fatty acyl group on membrane lipoproteins
E2P79_16190	COG0495	leucyl-tRNA aminoacylation
E2P79_16200	COG1466	dna polymerase III delta subunit
E2P79_16205	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
E2P79_16210	COG0799	negative regulation of ribosome biogenesis
E2P79_16215	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
E2P79_16220	COG0768	penicillin binding
E2P79_16225	COG0772	Belongs to the SEDS family
E2P79_16230	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
E2P79_16235	COG1686	Belongs to the peptidase S11 family
E2P79_16240	COG2921	Belongs to the UPF0250 family
E2P79_16245	COG0321	lipoyl(octanoyl) transferase activity
E2P79_16250	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
E2P79_16260	COG2731	YhcH YjgK YiaL family protein
E2P79_16270	COG1794	racemase activity, acting on amino acids and derivatives
E2P79_16285	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
E2P79_16300	COG0733	neurotransmitter:sodium symporter activity
E2P79_16330	COG0583	DNA-binding transcription factor activity
E2P79_16350	COG1511	domain protein
E2P79_16350	COG3264	Mechanosensitive ion channel
E2P79_16355	COG0584	glycerophosphoryl diester phosphodiesterase
E2P79_16365	COG1049	propionate catabolic process, 2-methylcitrate cycle
E2P79_16375	COG0840	transmembrane signaling receptor activity
E2P79_16385	COG3385	transposase activity
E2P79_16395	COG3706	GGDEF domain
E2P79_16400	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
E2P79_16405	COG0508	dehydrogenase complex catalyzes the overall conversion of
E2P79_16410	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
E2P79_16415	COG2186	Transcriptional regulator
E2P79_16440	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
E2P79_16445	COG1459	type II secretion system
E2P79_16460	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
E2P79_16465	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
E2P79_16470	COG0494	nUDIX hydrolase
E2P79_16475	COG0653	protein targeting
E2P79_16485	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
E2P79_16490	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
E2P79_16495	COG0849	cell division
E2P79_16505	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
E2P79_16510	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
E2P79_16515	COG0772	Belongs to the SEDS family
E2P79_16530	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
E2P79_16540	COG0768	penicillin binding
E2P79_16545	COG3116	cell division
E2P79_16550	COG0275	rRNA processing
E2P79_16555	COG2001	Belongs to the MraZ family
E2P79_16565	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
E2P79_16570	COG3107	peptidoglycan biosynthetic process
E2P79_16575	COG0792	nuclease activity
E2P79_16580	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
E2P79_16585	COG2823	Periplasmic or secreted lipoprotein
E2P79_16590	COG2969	positive regulation of protein catabolic process
E2P79_16595	COG0625	glutathione transferase activity
E2P79_16600	COG2857	Cytochrome c1
E2P79_16610	COG0723	plastoquinol--plastocyanin reductase activity
E2P79_16615	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
E2P79_16620	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
E2P79_16625	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
E2P79_16635	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
E2P79_16640	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
E2P79_16670	COG3964	amidohydrolase
E2P79_16690	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
E2P79_16695	COG1660	Displays ATPase and GTPase activities
E2P79_16700	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
E2P79_16710	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
E2P79_16715	COG1137	ATPase activity
E2P79_16720	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
E2P79_16725	COG3117	lipopolysaccharide transmembrane transporter activity
E2P79_16730	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
E2P79_16735	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
E2P79_16735	COG0517	IMP dehydrogenase activity
E2P79_16740	COG1127	ABC transporter
E2P79_16745	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
E2P79_16750	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
E2P79_16755	COG2854	intermembrane phospholipid transfer
E2P79_16765	COG5007	Belongs to the BolA IbaG family
E2P79_16770	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
E2P79_16775	COG0312	modulator of DNA gyrase
E2P79_16780	COG3028	Belongs to the UPF0307 family
E2P79_16790	COG0477	Major facilitator Superfamily
E2P79_16805	COG0359	binds to the 23S rRNA
E2P79_16810	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
E2P79_16815	COG0360	Binds together with S18 to 16S ribosomal RNA
E2P79_16820	COG1914	H( )-stimulated, divalent metal cation uptake system
E2P79_16835	COG1028	Short-chain dehydrogenase reductase Sdr
E2P79_16840	COG2814	Major facilitator Superfamily
E2P79_16880	COG2153	protein acetylation
E2P79_16890	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
E2P79_16905	COG0557	exoribonuclease II activity
E2P79_16910	COG3706	GGDEF domain
E2P79_16915	COG1854	S-ribosylhomocysteine lyase activity
E2P79_16930	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
E2P79_16930	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
E2P79_16940	COG0745	RESPONSE REGULATOR receiver
E2P79_16960	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
E2P79_16970	COG2204	response regulator
E2P79_17025	COG1129	ABC transporter
E2P79_17025	COG0842	Transport permease protein
E2P79_17035	COG0513	Belongs to the DEAD box helicase family
E2P79_17060	COG2957	Belongs to the agmatine deiminase family
E2P79_17075	COG1902	pentaerythritol trinitrate reductase activity
E2P79_17080	COG0456	acetyltransferase
E2P79_17085	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
E2P79_17105	COG0714	Associated with various cellular activities
E2P79_17115	COG0456	acetyltransferase
E2P79_17125	COG1022	Amp-dependent synthetase and ligase
E2P79_17130	COG2918	glutathione biosynthetic process
E2P79_17135	COG0612	Peptidase, M16
E2P79_17140	COG1238	metal cluster binding
E2P79_17175	COG3501	Rhs element vgr protein
E2P79_17285	COG0312	modulator of DNA gyrase
E2P79_17290	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
E2P79_17300	COG3164	Protein of unknown function
E2P79_17305	COG1530	ribonuclease E activity
E2P79_17310	COG0424	maF-like protein
E2P79_17315	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
E2P79_17320	COG1792	Involved in formation and maintenance of cell shape
E2P79_17325	COG1077	Cell shape determining protein MreB Mrl
E2P79_17370	COG1459	type II secretion system
E2P79_17375	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
E2P79_17385	COG3409	Peptidoglycan-binding domain 1 protein
E2P79_17385	COG3267	Type II secretory pathway component ExeA
E2P79_17420	COG2199	diguanylate cyclase activity
E2P79_17420	COG2200	EAL domain
E2P79_17430	COG0741	lytic transglycosylase activity
E2P79_17430	COG1388	LysM domain
E2P79_17445	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
E2P79_17450	COG1191	sigma factor activity
E2P79_17480	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
E2P79_17505	COG1706	bacterial-type flagellum-dependent cell motility
E2P79_17510	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
E2P79_17515	COG4786	Flagellar basal body rod
E2P79_17525	COG1749	Flagellar hook protein flgE
E2P79_17530	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
E2P79_17535	COG1558	bacterial-type flagellum-dependent cell motility
E2P79_17540	COG1815	bacterial-type flagellum-dependent cell motility
E2P79_17575	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
E2P79_17585	COG1677	Flagellar hook-basal body complex protein FliE
E2P79_17590	COG2204	response regulator
E2P79_17610	COG1987	bacterial-type flagellum assembly
E2P79_17640	COG2070	2-Nitropropane dioxygenase
E2P79_17650	COG2816	NAD+ diphosphatase activity
E2P79_17665	COG2964	Protein conserved in bacteria
E2P79_17670	COG3681	Belongs to the UPF0597 family
E2P79_17675	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
E2P79_17680	COG0564	pseudouridine synthase activity
E2P79_17690	COG0542	response to heat
E2P79_17700	COG3240	lipase activity
E2P79_17705	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
E2P79_17705	COG2885	chlorophyll binding
E2P79_17715	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
E2P79_17715	COG3008	intermembrane lipid transfer
E2P79_17720	COG2995	paraquat-inducible protein a
E2P79_17735	COG2203	Gaf domain
E2P79_17735	COG3706	GGDEF domain
E2P79_17735	COG5001	Diguanylate cyclase
E2P79_17735	COG4251	negative regulation of phosphorylation
E2P79_17740	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
E2P79_17745	COG2813	Specifically methylates the guanine in position
E2P79_17755	COG0297	glycogen (starch) synthase activity
E2P79_17800	COG1757	Na H antiporter
E2P79_17835	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
E2P79_17840	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
E2P79_17845	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
E2P79_17855	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
E2P79_17860	COG0084	hydrolase, TatD family'
E2P79_17875	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
E2P79_17880	COG4974	Belongs to the 'phage' integrase family
E2P79_17890	COG2932	Transcriptional regulator
E2P79_17970	COG4695	Portal protein
E2P79_18020	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
E2P79_18100	COG0795	lipopolysaccharide-transporting ATPase activity
E2P79_18105	COG0795	lipopolysaccharide-transporting ATPase activity
E2P79_18110	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
E2P79_18115	COG2927	DNA polymerase III (CHI subunit)
E2P79_18125	COG1253	flavin adenine dinucleotide binding
E2P79_18130	COG0586	Pfam SNARE associated Golgi protein
E2P79_18135	COG1686	Belongs to the peptidase S11 family
E2P79_18175	COG1444	tRNA N-acetyltransferase activity
E2P79_18180	COG0784	Response regulator, receiver
E2P79_18180	COG0835	chemotaxis
E2P79_18185	COG0516	GMP reductase activity
E2P79_18195	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
E2P79_18210	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
E2P79_18215	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
E2P79_18220	COG3178	'Phosphotransferase
E2P79_18225	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
E2P79_18235	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
E2P79_18240	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
E2P79_18250	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
E2P79_18260	COG3610	response to peptide
E2P79_18265	COG2966	Psort location CytoplasmicMembrane, score
E2P79_18270	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
E2P79_18275	COG0211	Belongs to the bacterial ribosomal protein bL27 family
E2P79_18280	COG0261	This protein binds to 23S rRNA in the presence of protein L20
E2P79_18285	COG0142	geranyltranstransferase activity
E2P79_18290	COG3385	transposase activity
E2P79_18295	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
E2P79_18300	COG0330	HflC and HflK could
E2P79_18310	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
E2P79_18315	COG1923	regulation of RNA biosynthetic process
E2P79_18320	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
E2P79_18330	COG0860	N-Acetylmuramoyl-L-alanine amidase
E2P79_18335	COG0802	atpase or kinase
E2P79_18340	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
E2P79_18340	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
E2P79_18395	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
E2P79_18400	COG1162	GTPase activity
E2P79_18410	COG4628	conserved protein (DUF2132)
E2P79_18435	COG5001	Diguanylate cyclase
E2P79_18440	COG3076	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome
E2P79_18445	COG3291	Pkd domain containing protein
E2P79_18445	COG4412	M6 family metalloprotease domain protein
E2P79_18455	COG0673	inositol 2-dehydrogenase activity
E2P79_18480	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
E2P79_18485	COG0635	Involved in the biosynthesis of porphyrin-containing compound
E2P79_18495	COG0789	Transcriptional regulator
E2P79_18500	COG0138	bifunctional purine biosynthesis protein purh
E2P79_18505	COG0151	Belongs to the GarS family
E2P79_18515	COG0300	oxidoreductase activity
E2P79_18530	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
E2P79_18535	COG0358	DNA primase activity
E2P79_18540	COG1610	YqeY-like protein
E2P79_18545	COG0828	Belongs to the bacterial ribosomal protein bS21 family
E2P79_18550	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
E2P79_18575	COG1132	(ABC) transporter
E2P79_18585	COG2897	thiosulfate sulfurtransferase activity
E2P79_18590	COG2066	Belongs to the glutaminase family
E2P79_18595	COG3171	Protein conserved in bacteria
E2P79_18600	COG0220	tRNA (guanine-N7-)-methyltransferase activity
E2P79_18610	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
E2P79_18615	COG0440	acetolactate synthase activity
E2P79_18620	COG0028	Belongs to the TPP enzyme family
E2P79_18645	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
E2P79_18650	COG0473	3-isopropylmalate dehydrogenase activity
E2P79_18655	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
E2P79_18660	COG0066	3-isopropylmalate dehydratase activity
E2P79_18675	COG4143	(ABC) transporter
E2P79_18680	COG1178	ABC-type Fe3 transport system permease component
E2P79_18690	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
E2P79_18700	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
E2P79_18740	COG0564	pseudouridine synthase activity
E2P79_18755	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
E2P79_18760	COG0534	Mate efflux family protein
E2P79_18770	COG1027	Aspartate ammonia-lyase
E2P79_18775	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
E2P79_18785	COG0477	Major facilitator Superfamily
E2P79_18805	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
E2P79_18815	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
E2P79_18815	COG0506	proline dehydrogenase activity
E2P79_18815	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
E2P79_18820	COG4991	sh3 domain protein
E2P79_18825	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
E2P79_18835	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
E2P79_18845	COG1349	DNA-binding transcription factor activity
E2P79_18855	COG0737	Belongs to the 5'-nucleotidase family
E2P79_18860	COG1280	lysine exporter protein (LysE YggA)
E2P79_18865	COG0583	DNA-binding transcription factor activity
E2P79_18870	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
E2P79_18880	COG0110	maltose O-acetyltransferase activity
E2P79_18920	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
E2P79_18925	COG2022	thiamine diphosphate biosynthetic process
E2P79_18935	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
E2P79_18940	COG0352	thiamine-phosphate diphosphorylase activity
E2P79_18945	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
E2P79_18950	COG0754	glutathionylspermidine amidase activity
E2P79_18960	COG3766	membrane
E2P79_18980	COG0745	RESPONSE REGULATOR receiver
E2P79_18990	COG3174	membrane
E2P79_18995	COG0110	maltose O-acetyltransferase activity
E2P79_19025	COG0218	Necessary for normal cell division and for the maintenance of normal septation
E2P79_19035	COG1546	Belongs to the CinA family
E2P79_19035	COG1058	Belongs to the CinA family
E2P79_19045	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
E2P79_19050	COG1490	D-aminoacyl-tRNA deacylase activity
E2P79_19060	COG0456	acetyltransferase
E2P79_19070	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
E2P79_19075	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
E2P79_19085	COG3265	gluconokinase activity
E2P79_19090	COG0129	dihydroxy-acid dehydratase activity
E2P79_19095	COG0800	Aldolase
E2P79_19100	COG1609	Transcriptional regulator
E2P79_19110	COG4942	peptidase
E2P79_19115	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
E2P79_19120	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
E2P79_19125	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
E2P79_19130	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
E2P79_19135	COG0316	Belongs to the HesB IscA family
E2P79_19135	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
E2P79_19145	COG0596	Alpha beta hydrolase
E2P79_19165	COG4533	DNA binding
E2P79_19175	COG2873	o-acetylhomoserine
E2P79_19185	COG1979	alcohol dehydrogenase
E2P79_19205	COG1285	pathogenesis
E2P79_19210	COG0635	Involved in the biosynthesis of porphyrin-containing compound
E2P79_19220	COG3078	GTPase activator activity
E2P79_19230	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
E2P79_19235	COG0408	coproporphyrinogen oxidase activity
E2P79_19240	COG0009	L-threonylcarbamoyladenylate synthase
E2P79_19245	COG0551	DNA topoisomerase type I activity
E2P79_19250	COG2922	Belongs to the Smg family
E2P79_19260	COG0242	peptide deformylase activity
E2P79_19265	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
E2P79_19270	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
E2P79_19270	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
E2P79_19275	COG0569	domain protein
E2P79_19280	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
E2P79_19285	COG1322	Protein conserved in bacteria
E2P79_19295	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
E2P79_19295	COG2221	Nitrite and sulphite reductase 4Fe-4S
E2P79_19310	COG0583	DNA-binding transcription factor activity
E2P79_19315	COG0518	GMP synthase (glutamine-hydrolyzing) activity
E2P79_19315	COG0519	Catalyzes the synthesis of GMP from XMP
E2P79_19330	COG1396	sequence-specific DNA binding
E2P79_19335	COG1012	belongs to the aldehyde dehydrogenase family
E2P79_19375	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
E2P79_19380	COG2146	nitrite reductase [NAD(P)H] activity
E2P79_19385	COG2116	formate transmembrane transporter activity
E2P79_19390	COG1648	precorrin-2 dehydrogenase activity
E2P79_19390	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
E2P79_19395	COG2239	Acts as a magnesium transporter
E2P79_19405	COG3706	GGDEF domain
E2P79_19410	COG1368	sulfuric ester hydrolase activity
E2P79_19440	COG1671	Belongs to the UPF0178 family
E2P79_19445	COG1988	membrane-bound metal-dependent
E2P79_19450	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
E2P79_19470	COG1683	Conserved Protein
E2P79_19475	COG0204	Acyl-transferase
E2P79_19480	COG0204	Acyl-transferase
E2P79_19485	COG0606	chelatase, subunit chli
E2P79_19500	COG3978	acetolactate synthase activity
E2P79_19525	COG1309	transcriptional regulator
E2P79_19580	COG4206	TonB-dependent receptor
E2P79_19585	COG0583	DNA-binding transcription factor activity
E2P79_19600	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
E2P79_19605	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
E2P79_19610	COG2223	nitrite transmembrane transporter activity
E2P79_19615	COG3279	Response regulator of the LytR AlgR family
E2P79_19620	COG3275	phosphorelay sensor kinase activity
E2P79_19625	COG2081	HI0933 family
E2P79_19630	COG1528	Iron-storage protein
E2P79_19635	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
E2P79_19640	COG0589	response to stress
E2P79_19665	COG3706	GGDEF domain
E2P79_19670	COG3642	lipopolysaccharide core region biosynthetic process
E2P79_19675	COG0859	PFAM glycosyl transferase family 9
E2P79_19685	COG1758	RNA polymerase activity
E2P79_19695	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
E2P79_19705	COG2267	carboxylic ester hydrolase activity
E2P79_19710	COG0561	phosphatase activity
E2P79_19755	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
E2P79_19760	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
E2P79_19785	COG2166	iron-sulfur cluster assembly
E2P79_19790	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
E2P79_19810	COG3306	glycosyltransferase involved in LPS biosynthesis
E2P79_19815	COG0438	transferase activity, transferring glycosyl groups
E2P79_19830	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
E2P79_19845	COG1063	alcohol dehydrogenase
E2P79_19855	COG1129	ABC transporter
E2P79_19865	COG3250	beta-galactosidase activity
E2P79_19870	COG1609	Transcriptional regulator
E2P79_19875	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
E2P79_19885	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
E2P79_19890	COG2017	converts alpha-aldose to the beta-anomer
E2P79_19895	COG1968	undecaprenyl-diphosphatase activity
E2P79_19900	COG1295	ribonuclease BN
E2P79_19910	COG0174	glutamine synthetase
E2P79_19920	COG3852	Histidine kinase
E2P79_19935	COG0668	transmembrane transport
E2P79_19940	COG1011	Hydrolase
E2P79_19945	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
E2P79_19955	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
E2P79_19960	COG0019	diaminopimelate decarboxylase activity
E2P79_19970	COG1965	Belongs to the frataxin family
E2P79_19990	COG1587	Uroporphyrinogen-III synthase
E2P79_19995	COG2959	enzyme of heme biosynthesis
E2P79_20010	COG2050	protein possibly involved in aromatic compounds catabolism
E2P79_20025	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
E2P79_20035	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
E2P79_20040	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
E2P79_20055	COG1494	fructose-1,6-bisphosphatase
E2P79_20075	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
E2P79_20080	COG0010	Belongs to the arginase family
E2P79_20085	COG1228	amidohydrolase
E2P79_20095	COG0288	reversible hydration of carbon dioxide
E2P79_20105	COG2177	Part of the ABC transporter FtsEX involved in
E2P79_20110	COG2884	Cell division ATP-binding protein ftsE
E2P79_20115	COG0552	protein localization to endoplasmic reticulum
E2P79_20120	COG0742	ribosomal rna small subunit methyltransferase
E2P79_20145	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
E2P79_20160	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
E2P79_20170	COG2095	MarC family integral membrane protein
E2P79_20180	COG1301	dicarboxylic acid transport
E2P79_20210	COG0203	ribosomal protein L17
E2P79_20215	COG0202	RNA polymerase activity
E2P79_20220	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
E2P79_20225	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
E2P79_20230	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
E2P79_20235	COG0257	Belongs to the bacterial ribosomal protein bL36 family
E2P79_20240	COG0201	protein transport
E2P79_20245	COG0200	Binds to the 23S rRNA
E2P79_20250	COG1841	ribosomal large subunit assembly
E2P79_20255	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
E2P79_20260	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
E2P79_20265	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
E2P79_20270	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
E2P79_20275	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
E2P79_20280	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
E2P79_20285	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
E2P79_20290	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
E2P79_20295	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
E2P79_20300	COG0255	Belongs to the universal ribosomal protein uL29 family
E2P79_20305	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
E2P79_20310	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
E2P79_20315	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
E2P79_20320	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
E2P79_20325	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
E2P79_20330	COG0089	rRNA binding
E2P79_20335	COG0088	Forms part of the polypeptide exit tunnel
E2P79_20340	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
E2P79_20345	COG0051	transcription antitermination factor activity, RNA binding
E2P79_20365	COG0165	Argininosuccinate lyase
E2P79_20370	COG0137	argininosuccinate synthase activity
E2P79_20380	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
E2P79_20385	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
E2P79_20395	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
E2P79_20410	COG3852	Histidine kinase
E2P79_20420	COG0460	homoserine dehydrogenase
E2P79_20420	COG0527	aspartate kinase activity
E2P79_20425	COG0626	cystathionine gamma-synthase activity
E2P79_20435	COG0814	amino acid
E2P79_20450	COG2885	chlorophyll binding
E2P79_20460	COG2818	Glycosylase
E2P79_20465	COG0752	glycyl-tRNA synthetase alpha subunit
E2P79_20470	COG0751	glycine-tRNA ligase activity
E2P79_20505	COG0814	amino acid
E2P79_20520	COG0348	domain, Protein
E2P79_20525	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
E2P79_20540	COG1609	Transcriptional regulator
E2P79_20550	COG0559	Belongs to the binding-protein-dependent transport system permease family
E2P79_20570	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
E2P79_20580	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
E2P79_20585	COG3161	chorismate lyase activity
E2P79_20605	COG1609	Transcriptional regulator
E2P79_20610	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
E2P79_20625	COG1519	Transferase
E2P79_20630	COG0859	PFAM glycosyl transferase family 9
E2P79_20635	COG1042	CoA-binding domain protein
E2P79_20635	COG0045	succinate-CoA ligase (ADP-forming) activity
E2P79_20635	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
E2P79_20665	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
E2P79_20670	COG0848	biopolymer transport protein
E2P79_20675	COG0811	peptide transport
E2P79_20680	COG0811	peptide transport
E2P79_20690	COG2771	luxR family
E2P79_20740	COG3977	Valine--pyruvate aminotransferase
E2P79_20745	COG0071	Belongs to the small heat shock protein (HSP20) family
E2P79_20750	COG0071	Belongs to the small heat shock protein (HSP20) family
E2P79_20755	COG0318	PFAM AMP-dependent synthetase and ligase
E2P79_20805	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
E2P79_20825	COG0187	DNA topoisomerase II activity
E2P79_20830	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
E2P79_20835	COG0592	DNA-directed DNA polymerase activity
E2P79_20840	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
E2P79_20855	COG1126	abc transporter atp-binding protein
E2P79_20860	COG0230	Belongs to the bacterial ribosomal protein bL34 family
E2P79_20865	COG0594	ribonuclease P activity
E2P79_20870	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
E2P79_20875	COG0706	membrane insertase activity