locus-tag	class	description
FE240_00015	COG0129	dihydroxy-acid dehydratase activity
FE240_00025	COG3978	acetolactate synthase activity
FE240_00040	COG0606	chelatase, subunit chli
FE240_00045	COG0204	Acyl-transferase
FE240_00050	COG0204	Acyl-transferase
FE240_00055	COG1683	Conserved Protein
FE240_00065	COG1335	isochorismatase
FE240_00075	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
FE240_00080	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
FE240_00090	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
FE240_00100	COG0514	ATP-dependent DNA helicase (RecQ)
FE240_00105	COG2050	protein possibly involved in aromatic compounds catabolism
FE240_00120	COG2959	enzyme of heme biosynthesis
FE240_00130	COG0181	hydroxymethylbilane synthase activity
FE240_00135	COG3072	Adenylate cyclase
FE240_00145	COG1965	Belongs to the frataxin family
FE240_00155	COG0019	diaminopimelate decarboxylase activity
FE240_00160	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
FE240_00170	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
FE240_00175	COG1011	Hydrolase
FE240_00180	COG2204	response regulator
FE240_00185	COG3852	Histidine kinase
FE240_00195	COG0174	glutamine synthetase
FE240_00200	COG1217	gtp-binding protein TYPA
FE240_00205	COG1295	ribonuclease BN
FE240_00210	COG2267	carboxylic ester hydrolase activity
FE240_00215	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FE240_00220	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
FE240_00225	COG1758	RNA polymerase activity
FE240_00235	COG0859	PFAM glycosyl transferase family 9
FE240_00240	COG3642	lipopolysaccharide core region biosynthetic process
FE240_00275	COG0589	response to stress
FE240_00280	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
FE240_00285	COG1528	Iron-storage protein
FE240_00290	COG2081	HI0933 family
FE240_00310	COG3188	usher protein
FE240_00330	COG2205	protein histidine kinase activity
FE240_00330	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FE240_00340	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
FE240_00345	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
FE240_00390	COG0166	Belongs to the GPI family
FE240_00400	COG0789	Transcriptional regulator
FE240_00405	COG4251	negative regulation of phosphorylation
FE240_00405	COG2203	Gaf domain
FE240_00405	COG5001	Diguanylate cyclase
FE240_00405	COG3706	GGDEF domain
FE240_00410	COG3084	Protein conserved in bacteria
FE240_00420	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
FE240_00425	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
FE240_00430	COG2183	response to ionizing radiation
FE240_00435	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
FE240_00450	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
FE240_00455	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
FE240_00465	COG3031	protein transport across the cell outer membrane
FE240_00470	COG1450	Type ii and iii secretion system protein
FE240_00475	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
FE240_00480	COG1459	type II secretion system
FE240_00485	COG2165	general secretion pathway protein
FE240_00495	COG2165	general secretion pathway protein
FE240_00500	COG4795	General secretion pathway protein
FE240_00505	COG3156	type II secretion system protein K
FE240_00515	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
FE240_00525	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
FE240_00530	COG4208	sulfate ABC transporter
FE240_00535	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
FE240_00540	COG0583	DNA-binding transcription factor activity
FE240_00560	COG4221	oxidoreductase activity
FE240_00565	COG1979	alcohol dehydrogenase
FE240_00575	COG2873	o-acetylhomoserine
FE240_00580	COG4533	DNA binding
FE240_00595	COG0596	Alpha beta hydrolase
FE240_00605	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
FE240_00605	COG0316	Belongs to the HesB IscA family
FE240_00610	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
FE240_00615	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
FE240_00620	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FE240_00625	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
FE240_00630	COG4942	peptidase
FE240_00635	COG0004	ammonium transporteR
FE240_00640	COG1609	Transcriptional regulator
FE240_00645	COG0800	Aldolase
FE240_00650	COG0129	dihydroxy-acid dehydratase activity
FE240_00655	COG3265	gluconokinase activity
FE240_00660	COG2610	gluconate transmembrane transporter activity
FE240_00665	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FE240_00670	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
FE240_00680	COG0456	acetyltransferase
FE240_00685	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
FE240_00690	COG1490	D-aminoacyl-tRNA deacylase activity
FE240_00695	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
FE240_00710	COG0218	Necessary for normal cell division and for the maintenance of normal septation
FE240_00715	COG1079	Belongs to the binding-protein-dependent transport system permease family
FE240_00720	COG4603	Belongs to the binding-protein-dependent transport system permease family
FE240_00725	COG3845	ABC transporter
FE240_00730	COG1744	ABC transporter substrate-binding protein PnrA-like
FE240_00735	COG0110	maltose O-acetyltransferase activity
FE240_00740	COG3174	membrane
FE240_00745	COG0642	Histidine kinase
FE240_00750	COG0745	RESPONSE REGULATOR receiver
FE240_00765	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
FE240_00770	COG0352	thiamine-phosphate diphosphorylase activity
FE240_00775	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
FE240_00785	COG2022	thiamine diphosphate biosynthetic process
FE240_00790	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
FE240_00830	COG0583	DNA-binding transcription factor activity
FE240_00840	COG1741	Belongs to the pirin family
FE240_00845	COG2259	Doxx family
FE240_00850	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
FE240_00855	COG1074	ATP-dependent DNA helicase activity
FE240_00860	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
FE240_00865	COG0513	Belongs to the DEAD box helicase family
FE240_00870	COG0523	cobalamin synthesis protein
FE240_00875	COG2879	small protein
FE240_00880	COG1966	Carbon starvation protein
FE240_00895	COG2070	2-Nitropropane dioxygenase
FE240_00900	COG0494	nUDIX hydrolase
FE240_00925	COG2321	neutral zinc metallopeptidase
FE240_00930	COG3681	Belongs to the UPF0597 family
FE240_00940	COG0446	pyridine nucleotide-disulphide oxidoreductase
FE240_00945	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FE240_00950	COG0564	pseudouridine synthase activity
FE240_00955	COG2233	PERMEase
FE240_00960	COG0151	Belongs to the GarS family
FE240_00965	COG0138	bifunctional purine biosynthesis protein purh
FE240_00970	COG0789	Transcriptional regulator
FE240_00980	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FE240_00985	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
FE240_00990	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
FE240_01000	COG0673	inositol 2-dehydrogenase activity
FE240_01025	COG0477	Major facilitator Superfamily
FE240_01030	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
FE240_01035	COG1027	Aspartate ammonia-lyase
FE240_01045	COG0534	Mate efflux family protein
FE240_01050	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
FE240_01055	COG0459	protein refolding
FE240_01090	COG0564	pseudouridine synthase activity
FE240_01095	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
FE240_01125	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
FE240_01130	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
FE240_01135	COG1178	ABC-type Fe3 transport system permease component
FE240_01140	COG4143	(ABC) transporter
FE240_01155	COG0066	3-isopropylmalate dehydratase activity
FE240_01160	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
FE240_01170	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
FE240_01190	COG0028	Belongs to the TPP enzyme family
FE240_01195	COG0440	acetolactate synthase activity
FE240_01200	COG2200	EAL domain
FE240_01205	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FE240_01215	COG0220	tRNA (guanine-N7-)-methyltransferase activity
FE240_01220	COG3171	Protein conserved in bacteria
FE240_01225	COG2066	Belongs to the glutaminase family
FE240_01230	COG2897	thiosulfate sulfurtransferase activity
FE240_01235	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
FE240_01255	COG3076	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome
FE240_01260	COG5001	Diguanylate cyclase
FE240_01280	COG4628	conserved protein (DUF2132)
FE240_01285	COG0688	phosphatidylethanolamine metabolic process
FE240_01290	COG1162	GTPase activity
FE240_01295	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
FE240_01350	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
FE240_01350	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
FE240_01355	COG0802	atpase or kinase
FE240_01365	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
FE240_01370	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
FE240_01375	COG1923	regulation of RNA biosynthetic process
FE240_01380	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
FE240_01385	COG0330	HflC and HflK could
FE240_01390	COG0330	HflC and HflK could
FE240_01395	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
FE240_01400	COG0142	geranyltranstransferase activity
FE240_01405	COG0261	This protein binds to 23S rRNA in the presence of protein L20
FE240_01410	COG0211	Belongs to the bacterial ribosomal protein bL27 family
FE240_01415	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
FE240_01420	COG2966	Psort location CytoplasmicMembrane, score
FE240_01425	COG3610	response to peptide
FE240_01435	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
FE240_01440	COG2967	ApaG domain
FE240_01445	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
FE240_01450	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
FE240_01460	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
FE240_01465	COG3178	'Phosphotransferase
FE240_01470	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
FE240_01475	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
FE240_01480	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FE240_01490	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
FE240_01500	COG0516	GMP reductase activity
FE240_01505	COG0784	Response regulator, receiver
FE240_01505	COG0835	chemotaxis
FE240_01510	COG1444	tRNA N-acetyltransferase activity
FE240_01550	COG1686	Belongs to the peptidase S11 family
FE240_01560	COG1253	flavin adenine dinucleotide binding
FE240_01565	COG0525	valine-tRNA ligase activity
FE240_01575	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
FE240_01580	COG0795	lipopolysaccharide-transporting ATPase activity
FE240_01585	COG0795	lipopolysaccharide-transporting ATPase activity
FE240_01600	COG0582	viral genome integration into host DNA
FE240_01655	COG0004	ammonium transporteR
FE240_01660	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
FE240_01665	COG0084	hydrolase, TatD family'
FE240_01670	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
FE240_01680	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
FE240_01685	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
FE240_01690	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
FE240_01695	COG0813	purine-nucleoside phosphorylase activity
FE240_01710	COG0560	Phosphoserine phosphatase
FE240_01730	COG1757	Na H antiporter
FE240_01770	COG0297	glycogen (starch) synthase activity
FE240_01775	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
FE240_01780	COG2813	Specifically methylates the guanine in position
FE240_01785	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FE240_01795	COG2995	paraquat-inducible protein a
FE240_01800	COG3008	intermembrane lipid transfer
FE240_01800	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
FE240_01815	COG0741	lytic transglycosylase activity
FE240_01820	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
FE240_01825	COG1194	a g-specific adenine glycosylase
FE240_01835	COG3409	Peptidoglycan-binding domain 1 protein
FE240_01835	COG3267	Type II secretory pathway component ExeA
FE240_01840	COG0617	tRNA 3'-terminal CCA addition
FE240_01845	COG0306	phosphate transporter
FE240_01850	COG1392	Phosphate transport regulator
FE240_01860	COG1560	Kdo2-lipid A biosynthetic process
FE240_01865	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
FE240_01865	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
FE240_01870	COG2827	Endonuclease containing a URI domain
FE240_01875	COG2962	Rard protein
FE240_01880	COG1573	uracil-dna glycosylase
FE240_01890	COG0583	DNA-binding transcription factor activity
FE240_01895	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FE240_01900	COG1121	(ABC) transporter
FE240_01905	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
FE240_01915	COG2358	TRAP transporter, solute receptor (TAXI family
FE240_01925	COG0739	heme binding
FE240_01930	COG0604	alcohol dehydrogenase
FE240_01935	COG1238	metal cluster binding
FE240_01940	COG0612	Peptidase, M16
FE240_01945	COG2918	glutathione biosynthetic process
FE240_01955	COG1022	Amp-dependent synthetase and ligase
FE240_01965	COG0456	acetyltransferase
FE240_01975	COG0714	Associated with various cellular activities
FE240_01980	COG2425	protein containing a von Willebrand factor type A (vWA) domain
FE240_02005	COG1902	pentaerythritol trinitrate reductase activity
FE240_02020	COG2957	Belongs to the agmatine deiminase family
FE240_02025	COG0154	amidase activity
FE240_02060	COG0513	Belongs to the DEAD box helicase family
FE240_02070	COG0789	Transcriptional regulator
FE240_02090	COG0577	efflux transmembrane transporter activity
FE240_02090	COG1136	(ABC) transporter
FE240_02095	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FE240_02100	COG0745	RESPONSE REGULATOR receiver
FE240_02110	COG2814	Major facilitator Superfamily
FE240_02120	COG1574	metal-dependent hydrolase with the TIM-barrel fold
FE240_02130	COG1335	isochorismatase
FE240_02135	COG0583	DNA-binding transcription factor activity
FE240_02140	COG0346	lactoylglutathione lyase activity
FE240_02145	COG2207	Transcriptional regulator
FE240_02175	COG2205	protein histidine kinase activity
FE240_02185	COG2204	response regulator
FE240_02195	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
FE240_02225	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
FE240_02225	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FE240_02240	COG1854	S-ribosylhomocysteine lyase activity
FE240_02245	COG3706	GGDEF domain
FE240_02255	COG0557	exoribonuclease II activity
FE240_02260	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FE240_02270	COG2153	protein acetylation
FE240_02300	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
FE240_02305	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
FE240_02315	COG0338	D12 class N6 adenine-specific DNA methyltransferase
FE240_02320	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
FE240_02330	COG0180	Tryptophanyl-tRNA synthetase
FE240_02345	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
FE240_02350	COG3138	arginine N-succinyltransferase
FE240_02355	COG1012	belongs to the aldehyde dehydrogenase family
FE240_02370	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FE240_02375	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
FE240_02380	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FE240_02385	COG0175	sulfate reduction
FE240_02395	COG3706	GGDEF domain
FE240_02400	COG2113	Glycine betaine
FE240_02405	COG4176	ABC-type proline glycine betaine transport system permease component
FE240_02410	COG4175	Glycine betaine
FE240_02415	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FE240_02430	COG0523	cobalamin synthesis protein
FE240_02435	COG0477	Major facilitator Superfamily
FE240_02445	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
FE240_02450	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
FE240_02480	COG3314	Sporulation integral membrane protein YlbJ
FE240_02485	COG1280	lysine exporter protein (LysE YggA)
FE240_02495	COG2261	transglycosylase associated protein
FE240_02510	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
FE240_02515	COG1053	succinate dehydrogenase
FE240_02525	COG0584	glycerophosphoryl diester phosphodiesterase
FE240_02530	COG1511	domain protein
FE240_02530	COG3264	Mechanosensitive ion channel
FE240_02535	COG4942	peptidase
FE240_02550	COG0513	Belongs to the DEAD box helicase family
FE240_02555	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
FE240_02575	COG0735	belongs to the Fur family
FE240_02580	COG1007	ATP synthesis coupled electron transport
FE240_02585	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FE240_02595	COG0713	ATP synthesis coupled electron transport
FE240_02600	COG0839	Belongs to the complex I subunit 6 family
FE240_02605	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FE240_02610	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
FE240_02615	COG1034	ATP synthesis coupled electron transport
FE240_02630	COG0649	NAD binding
FE240_02630	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FE240_02635	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FE240_02640	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FE240_02645	COG1360	Flagellar Motor Protein
FE240_02650	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
FE240_02665	COG0745	RESPONSE REGULATOR receiver
FE240_02670	COG3104	oligopeptide transport
FE240_02675	COG1210	Utp--glucose-1-phosphate uridylyltransferase
FE240_02680	COG1555	photosystem II stabilization
FE240_02685	COG1218	3'(2'),5'-bisphosphate nucleotidase
FE240_02690	COG2350	Protein conserved in bacteria
FE240_02695	COG2917	probably involved in intracellular septation
FE240_02700	COG0076	glutamate decarboxylase activity
FE240_02705	COG2985	domain, Protein
FE240_02705	COG0569	domain protein
FE240_02715	COG1278	Cold shock
FE240_02725	COG0840	transmembrane signaling receptor activity
FE240_02730	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FE240_02765	COG0835	chemotaxis
FE240_02765	COG0784	Response regulator, receiver
FE240_02775	COG4181	ATPase activity
FE240_02780	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
FE240_02785	COG1090	epimerase
FE240_02790	COG0857	belongs to the CobB CobQ family
FE240_02790	COG0280	phosphate acetyltransferase
FE240_02795	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
FE240_02800	COG3092	negative regulation of chromosome organization
FE240_02805	COG3013	Belongs to the UPF0304 family
FE240_02810	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
FE240_02815	COG2716	regulation of RNA biosynthetic process
FE240_02825	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
FE240_02830	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
FE240_02835	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
FE240_02840	COG0142	geranyltranstransferase activity
FE240_02845	COG1722	exodeoxyribonuclease VII activity
FE240_02850	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
FE240_02855	COG1360	Flagellar Motor Protein
FE240_02870	COG1534	Rna-binding protein
FE240_02875	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
FE240_02880	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FE240_02885	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
FE240_02890	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FE240_02895	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
FE240_02910	COG0779	Required for maturation of 30S ribosomal subunits
FE240_02915	COG0195	Participates in both transcription termination and antitermination
FE240_02920	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
FE240_02925	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
FE240_02930	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
FE240_02935	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
FE240_02940	COG1185	polyribonucleotide nucleotidyltransferase activity
FE240_02945	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
FE240_02950	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
FE240_02965	COG0583	DNA-binding transcription factor activity
FE240_02990	COG0561	phosphatase activity
FE240_03005	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FE240_03020	COG1794	racemase activity, acting on amino acids and derivatives
FE240_03030	COG2731	YhcH YjgK YiaL family protein
FE240_03040	COG3545	Serine hydrolase
FE240_03045	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
FE240_03050	COG0321	lipoyl(octanoyl) transferase activity
FE240_03055	COG2921	Belongs to the UPF0250 family
FE240_03060	COG1686	Belongs to the peptidase S11 family
FE240_03065	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
FE240_03070	COG0772	Belongs to the SEDS family
FE240_03075	COG0768	penicillin binding
FE240_03080	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
FE240_03085	COG0799	negative regulation of ribosome biogenesis
FE240_03090	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
FE240_03095	COG1466	dna polymerase III delta subunit
FE240_03100	COG2980	Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane
FE240_03105	COG0495	leucyl-tRNA aminoacylation
FE240_03115	COG0815	Transfers the fatty acyl group on membrane lipoproteins
FE240_03120	COG4535	Mg2 and Co2 transporter CorC
FE240_03125	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
FE240_03130	COG1702	phosphate starvation-inducible protein PhoH
FE240_03135	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
FE240_03140	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FE240_03145	COG1803	Methylglyoxal synthase
FE240_03155	COG0252	asparaginase activity
FE240_03175	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FE240_03175	COG1263	PTS System
FE240_03180	COG0366	Alpha amylase catalytic
FE240_03185	COG0110	maltose O-acetyltransferase activity
FE240_03210	COG0531	amino acid
FE240_03215	COG0366	Alpha amylase catalytic
FE240_03230	COG0463	Glycosyl transferase, family 2
FE240_03240	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FE240_03245	COG2989	Protein conserved in bacteria
FE240_03250	COG3108	Peptidase M15
FE240_03260	COG2860	membrane
FE240_03270	COG1196	nuclear chromosome segregation
FE240_03275	COG3115	cell septum assembly
FE240_03280	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
FE240_03290	COG1328	CTP reductase activity
FE240_03295	COG0602	queuosine metabolic process
FE240_03300	COG2195	Cleaves the N-terminal amino acid of tripeptides
FE240_03305	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
FE240_03310	COG1073	alpha beta
FE240_03325	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
FE240_03335	COG0589	response to stress
FE240_03350	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FE240_03355	COG2313	pseudouridylate synthase activity
FE240_03365	COG0521	Mo-molybdopterin cofactor biosynthetic process
FE240_03375	COG2252	PERMEase
FE240_03385	COG0488	(ABC) transporter
FE240_03390	COG0741	lytic transglycosylase activity
FE240_03395	COG0463	Glycosyl transferase, family 2
FE240_03425	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FE240_03430	COG4558	Periplasmic binding protein
FE240_03435	COG3721	Heme iron utilization protein
FE240_03440	COG0748	coenzyme F420 binding
FE240_03450	COG4638	Rieske (2fe-2S)
FE240_03455	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
FE240_03460	COG0543	2 iron, 2 sulfur cluster binding
FE240_03460	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
FE240_03525	COG2814	Major facilitator Superfamily
FE240_03530	COG2205	protein histidine kinase activity
FE240_03540	COG0442	prolyl-tRNA aminoacylation
FE240_03550	COG0632	four-way junction helicase activity
FE240_03555	COG2255	four-way junction helicase activity
FE240_03560	COG1271	oxidase subunit
FE240_03565	COG1294	oxidase, subunit
FE240_03570	COG4890	Cyd operon protein YbgT
FE240_03580	COG0824	Thioesterase
FE240_03585	COG0811	peptide transport
FE240_03595	COG3064	Membrane
FE240_03600	COG0823	Involved in the tonB-independent uptake of proteins
FE240_03605	COG2885	chlorophyll binding
FE240_03610	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
FE240_03680	COG0840	transmembrane signaling receptor activity
FE240_03685	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
FE240_03695	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
FE240_03700	COG1640	4-alpha-glucanotransferase
FE240_03705	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
FE240_03730	COG3139	Protein of unknown function (DUF1315)
FE240_03735	COG0252	asparaginase activity
FE240_03740	COG0786	glutamate:sodium symporter activity
FE240_03745	COG0616	signal peptide processing
FE240_03750	COG0446	pyridine nucleotide-disulphide oxidoreductase
FE240_03750	COG1902	pentaerythritol trinitrate reductase activity
FE240_03755	COG0778	Nitroreductase
FE240_03760	COG1522	sequence-specific DNA binding
FE240_03770	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FE240_03775	COG1946	Acyl-CoA thioesterase
FE240_03790	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
FE240_03795	COG0038	chloride channel
FE240_03805	COG0316	Belongs to the HesB IscA family
FE240_03850	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
FE240_03865	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FE240_03885	COG2264	protein methyltransferase activity
FE240_03890	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
FE240_03895	COG1489	DNA binding
FE240_03900	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
FE240_03905	COG1643	Atp-dependent helicase
FE240_03910	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FE240_03915	COG0346	lactoylglutathione lyase activity
FE240_03925	COG0671	phosphoesterase, PA-phosphatase related
FE240_03945	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
FE240_03950	COG0826	peptidase U32
FE240_03955	COG2200	EAL domain
FE240_03955	COG2199	diguanylate cyclase activity
FE240_03955	COG2203	Gaf domain
FE240_03960	COG1283	sodium-dependent phosphate transmembrane transporter activity
FE240_03970	COG0531	amino acid
FE240_03975	COG0531	amino acid
FE240_03985	COG1012	belongs to the aldehyde dehydrogenase family
FE240_03990	COG0174	glutamine synthetase
FE240_03995	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FE240_04000	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FE240_04000	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FE240_04000	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FE240_04005	COG0405	Gamma-glutamyltransferase
FE240_04015	COG2207	Transcriptional regulator
FE240_04025	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FE240_04045	COG2916	Histone family protein nucleoid-structuring protein H-NS
FE240_04050	COG3264	Mechanosensitive ion channel
FE240_04050	COG1196	nuclear chromosome segregation
FE240_04055	COG2190	(PTS) system
FE240_04065	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
FE240_04085	COG1720	tRNA m6t6A37 methyltransferase activity
FE240_04100	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
FE240_04105	COG4988	ABC transporter
FE240_04120	COG0745	RESPONSE REGULATOR receiver
FE240_04130	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
FE240_04140	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FE240_04150	COG2199	diguanylate cyclase activity
FE240_04150	COG2202	Pas domain
FE240_04150	COG2200	EAL domain
FE240_04160	COG3381	protein complex oligomerization
FE240_04175	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
FE240_04180	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
FE240_04185	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FE240_04185	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FE240_04200	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
FE240_04205	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
FE240_04210	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
FE240_04215	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
FE240_04225	COG0747	negative chemotaxis
FE240_04230	COG0601	transmembrane transport
FE240_04235	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FE240_04260	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
FE240_04265	COG0739	heme binding
FE240_04270	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
FE240_04305	COG0791	NLP P60 protein
FE240_04315	COG1309	transcriptional regulator
FE240_04320	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FE240_04325	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FE240_04335	COG1482	cell wall glycoprotein biosynthetic process
FE240_04345	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
FE240_04355	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
FE240_04360	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
FE240_04365	COG2723	6-phospho-beta-galactosidase activity
FE240_04370	COG1447	Phosphotransferase system cellobiose-specific component IIA
FE240_04375	COG1940	carbohydrate kinase activity
FE240_04380	COG4580	involved in the transport of maltose and maltodextrins
FE240_04400	COG1609	Transcriptional regulator
FE240_04410	COG0159	tryptophan synthase activity
FE240_04415	COG0133	tryptophan synthase activity
FE240_04420	COG0134	indole-3-glycerol-phosphate synthase activity
FE240_04420	COG0135	phosphoribosylanthranilate isomerase activity
FE240_04425	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
FE240_04430	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
FE240_04430	COG0512	Glutamine amidotransferase of anthranilate synthase
FE240_04435	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
FE240_04440	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
FE240_04445	COG0613	PHP domain protein
FE240_04450	COG0009	L-threonylcarbamoyladenylate synthase
FE240_04460	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
FE240_04490	COG0668	transmembrane transport
FE240_04495	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
FE240_04505	COG0488	(ABC) transporter
FE240_04520	COG0330	HflC and HflK could
FE240_04525	COG0243	molybdopterin cofactor binding
FE240_04535	COG1116	anion transmembrane transporter activity
FE240_04535	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FE240_04540	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FE240_04545	COG1116	anion transmembrane transporter activity
FE240_04550	COG2146	nitrite reductase [NAD(P)H] activity
FE240_04550	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FE240_04555	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FE240_04555	COG2146	nitrite reductase [NAD(P)H] activity
FE240_04560	COG1648	precorrin-2 dehydrogenase activity
FE240_04560	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
FE240_04565	COG0175	sulfate reduction
FE240_04570	COG2895	sulfate adenylyltransferase (ATP) activity
FE240_04575	COG3273	potassium ion transport
FE240_04575	COG0471	metal ion transport
FE240_04580	COG0529	Catalyzes the synthesis of activated sulfate
FE240_04605	COG3550	peptidyl-serine autophosphorylation
FE240_04610	COG1396	sequence-specific DNA binding
FE240_04615	COG1560	Kdo2-lipid A biosynthetic process
FE240_04635	COG1136	(ABC) transporter
FE240_04650	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
FE240_04665	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
FE240_04670	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
FE240_04675	COG0163	prenyltransferase activity
FE240_04690	COG1131	(ABC) transporter
FE240_04695	COG0842	Transport permease protein
FE240_04700	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
FE240_04705	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
FE240_04710	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
FE240_04720	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FE240_04725	COG1263	PTS System
FE240_04725	COG2190	(PTS) system
FE240_04725	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FE240_04730	COG4145	pantothenate transmembrane transporter activity
FE240_04740	COG0439	Biotin carboxylase
FE240_04745	COG0511	ligase activity, forming carbon-carbon bonds
FE240_04750	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
FE240_04760	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
FE240_04765	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
FE240_04770	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
FE240_04780	COG0083	homoserine kinase activity
FE240_04785	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
FE240_04795	COG1846	Transcriptional regulator
FE240_04800	COG2205	protein histidine kinase activity
FE240_04800	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FE240_04815	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FE240_04820	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FE240_04825	COG0745	RESPONSE REGULATOR receiver
FE240_04830	COG5000	phosphorelay sensor kinase activity
FE240_04830	COG5002	protein histidine kinase activity
FE240_04845	COG1447	Phosphotransferase system cellobiose-specific component IIA
FE240_04850	COG2723	6-phospho-beta-galactosidase activity
FE240_04860	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
FE240_04865	COG2273	Hydrolase Family 16
FE240_04865	COG5297	Belongs to the glycosyl hydrolase family 6
FE240_04870	COG1472	Belongs to the glycosyl hydrolase 3 family
FE240_04875	COG2182	Extracellular solute-binding protein
FE240_04880	COG1609	Transcriptional regulator
FE240_04900	COG0659	secondary active sulfate transmembrane transporter activity
FE240_04915	COG2271	Major facilitator Superfamily
FE240_04930	COG0625	glutathione transferase activity
FE240_04935	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FE240_04945	COG0840	transmembrane signaling receptor activity
FE240_04950	COG4932	domain protein
FE240_04950	COG5492	domain, Protein
FE240_04965	COG0702	epimerase
FE240_04970	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FE240_04975	COG1454	alcohol dehydrogenase
FE240_04995	COG0497	DNA recombination
FE240_05000	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
FE240_05005	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
FE240_05010	COG0443	Heat shock 70 kDa protein
FE240_05015	COG0484	heat shock protein binding
FE240_05045	COG1285	pathogenesis
FE240_05090	COG0095	Lipoate-protein ligase
FE240_05105	COG2207	Transcriptional regulator
FE240_05110	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
FE240_05115	COG0673	inositol 2-dehydrogenase activity
FE240_05120	COG3384	dioxygenase
FE240_05145	COG0788	formyltetrahydrofolate deformylase activity
FE240_05150	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FE240_05160	COG3118	belongs to the thioredoxin family
FE240_05170	COG0791	NLP P60 protein
FE240_05175	COG3129	Specifically methylates the adenine in position 1618 of 23S rRNA
FE240_05195	COG0746	molybdenum cofactor guanylyltransferase activity
FE240_05200	COG1116	anion transmembrane transporter activity
FE240_05205	COG4662	Binding-protein-dependent transport system inner membrane component
FE240_05220	COG3852	Histidine kinase
FE240_05230	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
FE240_05260	COG3383	formate dehydrogenase (NAD+) activity
FE240_05260	COG3383	formate dehydrogenase (NAD+) activity
FE240_05265	COG0437	4 iron, 4 sulfur cluster binding
FE240_05295	COG1881	PFAM PEBP family protein
FE240_05300	COG0708	Exodeoxyribonuclease III
FE240_05335	COG1280	lysine exporter protein (LysE YggA)
FE240_05345	COG3263	regulation of cellular component size
FE240_05355	COG1876	peptidase activity
FE240_05360	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FE240_05365	COG1393	Belongs to the ArsC family
FE240_05370	COG0105	UTP biosynthetic process
FE240_05375	COG0820	rRNA (adenine-C2-)-methyltransferase activity
FE240_05390	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
FE240_05395	COG0124	histidyl-tRNA synthetase
FE240_05400	COG2976	Protein conserved in bacteria
FE240_05405	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FE240_05410	COG1160	GTP binding
FE240_05415	COG1645	bacterial-type flagellum-dependent swarming motility
FE240_05420	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
FE240_05435	COG0436	Aminotransferase
FE240_05445	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
FE240_05450	COG2027	D-alanyl-D-alanine carboxypeptidase
FE240_05455	COG1061	Type III restriction enzyme res subunit
FE240_05460	COG1566	PFAM secretion protein HlyD family protein
FE240_05470	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
FE240_05500	COG0590	tRNA wobble adenosine to inosine editing
FE240_05505	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
FE240_05535	COG0716	FMN binding
FE240_05550	COG0596	Alpha beta hydrolase
FE240_05555	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
FE240_05560	COG0033	Phosphoglucomutase
FE240_05570	COG4574	serine-type endopeptidase inhibitor activity
FE240_05595	COG1187	pseudouridine synthase activity
FE240_05605	COG4166	transmembrane transport
FE240_05610	COG0622	Phosphoesterase
FE240_05630	COG0835	chemotaxis
FE240_05630	COG0784	Response regulator, receiver
FE240_05635	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
FE240_05640	COG1815	bacterial-type flagellum-dependent cell motility
FE240_05660	COG4787	bacterial-type flagellum-dependent cell motility
FE240_05665	COG4786	Flagellar basal body rod
FE240_05670	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
FE240_05675	COG1706	bacterial-type flagellum-dependent cell motility
FE240_05695	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
FE240_05700	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
FE240_05740	COG2089	acid synthase
FE240_05755	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
FE240_05760	COG1861	Spore coat polysaccharide biosynthesis protein F CMP-KDO synthetase
FE240_05770	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
FE240_05775	COG1086	Polysaccharide biosynthesis protein
FE240_05780	COG2239	Acts as a magnesium transporter
FE240_05790	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
FE240_05795	COG2716	regulation of RNA biosynthetic process
FE240_05805	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
FE240_05810	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
FE240_05815	COG1349	DNA-binding transcription factor activity
FE240_05820	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
FE240_05825	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
FE240_05830	COG0287	Prephenate dehydrogenase
FE240_05830	COG1605	Chorismate mutase
FE240_05835	COG0583	DNA-binding transcription factor activity
FE240_05840	COG3085	chromosome segregation
FE240_05845	COG1940	carbohydrate kinase activity
FE240_05845	COG1846	Transcriptional regulator
FE240_05850	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
FE240_05855	COG0363	glucosamine-6-phosphate deaminase activity
FE240_05860	COG2190	(PTS) system
FE240_05860	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FE240_05860	COG1263	PTS System
FE240_05870	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FE240_05875	COG0735	belongs to the Fur family
FE240_05885	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
FE240_05890	COG1677	Flagellar hook-basal body complex protein FliE
FE240_05900	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
FE240_05955	COG1684	flagellar biosynthetic protein fliR
FE240_05965	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
FE240_05990	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
FE240_05995	COG0784	Response regulator, receiver
FE240_05995	COG0643	Histidine kinase
FE240_05995	COG2198	Histidine kinase
FE240_06005	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
FE240_06010	COG1360	Flagellar Motor Protein
FE240_06015	COG1192	Involved in chromosome partitioning
FE240_06025	COG0835	chemotaxis
FE240_06035	COG4133	protoheme IX ABC transporter activity
FE240_06040	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
FE240_06045	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
FE240_06050	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
FE240_06055	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
FE240_06060	COG1138	Cytochrome C-type biogenesis protein
FE240_06065	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FE240_06070	COG4235	cytochrome complex assembly
FE240_06070	COG3088	subunit of a heme lyase
FE240_06090	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
FE240_06110	COG0259	pyridoxamine-phosphate oxidase activity
FE240_06115	COG3153	acetyltransferase
FE240_06120	COG0701	Predicted permease
FE240_06125	COG2850	peptidyl-arginine hydroxylation
FE240_06130	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
FE240_06135	COG2915	High frequency lysogenization protein hflD homolog
FE240_06140	COG0482	sulfurtransferase activity
FE240_06165	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FE240_06170	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FE240_06175	COG0538	isocitrate dehydrogenase activity
FE240_06205	COG0798	PFAM Bile acid sodium symporter
FE240_06220	COG1448	Aminotransferase
FE240_06230	COG0564	pseudouridine synthase activity
FE240_06245	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
FE240_06255	COG0625	glutathione transferase activity
FE240_06270	COG3437	response regulator, receiver
FE240_06275	COG0583	DNA-binding transcription factor activity
FE240_06300	COG2814	Major facilitator Superfamily
FE240_06315	COG1960	acyl-CoA dehydrogenase activity
FE240_06320	COG0469	pyruvate kinase activity
FE240_06325	COG1737	Transcriptional regulator
FE240_06330	COG0837	glucose binding
FE240_06340	COG4235	cytochrome complex assembly
FE240_06340	COG3088	subunit of a heme lyase
FE240_06350	COG1138	Cytochrome C-type biogenesis protein
FE240_06355	COG3301	Polysulphide reductase, NrfD
FE240_06360	COG0437	4 iron, 4 sulfur cluster binding
FE240_06365	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
FE240_06375	COG0247	lactate metabolic process
FE240_06380	COG3075	Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses fumarate or nitrate as electron acceptor
FE240_06385	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
FE240_06395	COG3012	SEC-C Motif Domain Protein
FE240_06405	COG1846	Transcriptional regulator
FE240_06405	COG1940	carbohydrate kinase activity
FE240_06410	COG1882	Formate acetyltransferase
FE240_06415	COG2116	formate transmembrane transporter activity
FE240_06420	COG1944	ATP diphosphatase activity
FE240_06430	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
FE240_06435	COG1368	sulfuric ester hydrolase activity
FE240_06440	COG0527	aspartate kinase activity
FE240_06445	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
FE240_06445	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
FE240_06450	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FE240_06470	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
FE240_06475	COG0583	DNA-binding transcription factor activity
FE240_06480	COG1620	l-lactate permease
FE240_06490	COG1139	Iron-sulfur cluster binding protein
FE240_06530	COG0577	efflux transmembrane transporter activity
FE240_06545	COG2814	Major facilitator Superfamily
FE240_06560	COG1635	Involved in the biosynthesis of the thiazole moiety of thiamine. Catalyzes the conversion of NAD and glycine to adenosine diphosphate 5-(2-hydroxyethyl)-4-methylthiazole-2-carboxylate (ADT), an adenylated thiazole intermediate, using free sulfide as a source of sulfur
FE240_06565	COG0672	)-iron permease
FE240_06590	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
FE240_06595	COG2885	chlorophyll binding
FE240_06600	COG1253	flavin adenine dinucleotide binding
FE240_06610	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
FE240_06615	COG0123	including yeast histone deacetylase and acetoin utilization protein
FE240_06620	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
FE240_06625	COG1199	ATP-dependent helicase activity
FE240_06635	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
FE240_06640	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
FE240_06650	COG4591	ABC-type transport system involved in lipoprotein release permease component
FE240_06655	COG1136	(ABC) transporter
FE240_06660	COG4591	ABC-type transport system involved in lipoprotein release permease component
FE240_06665	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
FE240_06675	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
FE240_06680	COG2894	cell division
FE240_06685	COG0850	regulation of cytokinetic process
FE240_06690	COG3100	YcgL domain-containing protein
FE240_06695	COG2983	Belongs to the UPF0260 family
FE240_06700	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
FE240_06705	COG3067	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
FE240_06715	COG2719	SpoVR family
FE240_06720	COG2718	Belongs to the UPF0229 family
FE240_06725	COG2766	serine protein kinase
FE240_06735	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
FE240_06740	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
FE240_06745	COG0291	Belongs to the bacterial ribosomal protein bL35 family
FE240_06750	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
FE240_06755	COG0488	(ABC) transporter
FE240_06760	COG3706	GGDEF domain
FE240_06765	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FE240_06770	COG3162	membrane
FE240_06785	COG1024	Enoyl-CoA hydratase
FE240_06790	COG1115	amino acid carrier protein
FE240_06800	COG3228	Belongs to the MtfA family
FE240_06805	COG1584	GPR1 FUN34 yaaH family protein
FE240_06830	COG4770	biotin carboxylase activity
FE240_06840	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
FE240_06845	COG1960	acyl-CoA dehydrogenase activity
FE240_06855	COG1960	acyl-CoA dehydrogenase activity
FE240_06860	COG1024	Enoyl-CoA hydratase
FE240_06865	COG1024	Enoyl-CoA hydratase
FE240_06875	COG1028	Short-chain dehydrogenase reductase Sdr
FE240_06885	COG0730	response to heat
FE240_06920	COG3121	Chaperone
FE240_06950	COG1342	Belongs to the UPF0251 family
FE240_06955	COG0583	DNA-binding transcription factor activity
FE240_06960	COG2723	6-phospho-beta-galactosidase activity
FE240_06975	COG0537	adenosine 5'-monophosphoramidase activity
FE240_07010	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FE240_07015	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FE240_07020	COG1733	regulation of RNA biosynthetic process
FE240_07035	COG2354	Protein conserved in bacteria
FE240_07045	COG1252	NADH dehydrogenase
FE240_07050	COG0393	Putative heavy-metal-binding
FE240_07055	COG0604	alcohol dehydrogenase
FE240_07070	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
FE240_07085	COG0567	Dehydrogenase, E1 component
FE240_07090	COG0508	dehydrogenase complex catalyzes the overall conversion of
FE240_07095	COG0045	succinate-CoA ligase (ADP-forming) activity
FE240_07110	COG1760	l-serine dehydratase
FE240_07115	COG1760	l-serine dehydratase
FE240_07120	COG0814	amino acid
FE240_07125	COG0494	nUDIX hydrolase
FE240_07130	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
FE240_07155	COG0581	inorganic phosphate transmembrane transporter activity
FE240_07160	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
FE240_07165	COG0704	Plays a role in the regulation of phosphate uptake
FE240_07170	COG0346	lactoylglutathione lyase activity
FE240_07175	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
FE240_07180	COG4660	Part of a membrane complex involved in electron transport
FE240_07185	COG4659	FMN binding
FE240_07190	COG4658	electron transport chain
FE240_07200	COG2878	Part of a membrane complex involved in electron transport
FE240_07205	COG4657	Part of a membrane complex involved in electron transport
FE240_07240	COG0714	Associated with various cellular activities
FE240_07245	COG0183	Belongs to the thiolase family
FE240_07250	COG1024	Enoyl-CoA hydratase
FE240_07250	COG1250	3-hydroxyacyl-CoA dehydrogenase
FE240_07260	COG4681	YaeQ
FE240_07275	COG0586	Pfam SNARE associated Golgi protein
FE240_07280	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FE240_07290	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
FE240_07315	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FE240_07320	COG1120	ATPase activity
FE240_07325	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FE240_07330	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FE240_07335	COG0673	inositol 2-dehydrogenase activity
FE240_07340	COG0583	DNA-binding transcription factor activity
FE240_07360	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
FE240_07365	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
FE240_07365	COG0574	Belongs to the PEP-utilizing enzyme family
FE240_07380	COG2824	Alkylphosphonate utilization operon protein PhnA
FE240_07385	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FE240_07390	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
FE240_07435	COG2119	membrane
FE240_07440	COG0023	Translation Initiation Factor
FE240_07450	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
FE240_07470	COG4139	cobalamin transport
FE240_07475	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
FE240_07480	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
FE240_07485	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
FE240_07490	COG0544	peptidyl-prolyl cis-trans isomerase activity
FE240_07495	COG0740	serine-type endopeptidase activity
FE240_07500	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
FE240_07505	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
FE240_07510	COG0776	regulation of translation
FE240_07515	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FE240_07520	COG4166	transmembrane transport
FE240_07525	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
FE240_07530	COG0814	amino acid
FE240_07535	COG1609	Transcriptional regulator
FE240_07540	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
FE240_07540	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
FE240_07545	COG1105	Belongs to the carbohydrate kinase PfkB family
FE240_07550	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
FE240_07550	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FE240_07550	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FE240_07555	COG3313	Fe-S protein
FE240_07560	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
FE240_07565	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
FE240_07595	COG1518	maintenance of DNA repeat elements
FE240_07600	COG1203	CRISPR-associated helicase, Cas3
FE240_07635	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
FE240_07640	COG1704	LemA family
FE240_07645	COG3770	Murein endopeptidase that cleaves the D-alanyl-meso-2,6- diamino-pimelyl amide bond that connects peptidoglycan strands. Likely plays a role in the removal of murein from the sacculus
FE240_07655	COG0724	RNA recognition motif
FE240_07660	COG4989	oxidoreductase activity
FE240_07675	COG0367	asparagine synthase
FE240_07680	COG0647	UMP catabolic process
FE240_07690	COG3134	Outer membrane lipoprotein
FE240_07695	COG0697	spore germination
FE240_07700	COG1278	Cold shock
FE240_07705	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
FE240_07710	COG0542	response to heat
FE240_07715	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
FE240_07720	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
FE240_07725	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
FE240_07730	COG3134	Outer membrane lipoprotein
FE240_07740	COG0492	ferredoxin-NADP+ reductase activity
FE240_07750	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FE240_07755	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
FE240_07765	COG0101	tRNA pseudouridine synthase activity
FE240_07770	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
FE240_07775	COG0285	dihydrofolate synthase activity
FE240_07780	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
FE240_07785	COG2920	part of a sulfur-relay system
FE240_07790	COG1289	transmembrane transporter activity
FE240_07795	COG0670	Belongs to the BI1 family
FE240_07835	COG0307	riboflavin synthase, alpha
FE240_07850	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FE240_07855	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
FE240_07860	COG0697	spore germination
FE240_07865	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
FE240_07900	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FE240_07905	COG3099	Belongs to the UPF0263 family
FE240_07920	COG0513	Belongs to the DEAD box helicase family
FE240_07925	COG0386	Belongs to the glutathione peroxidase family
FE240_07935	COG1181	Belongs to the D-alanine--D-alanine ligase family
FE240_07940	COG3148	PFAM DTW domain containing protein
FE240_07945	COG0730	response to heat
FE240_07950	COG0583	DNA-binding transcription factor activity
FE240_07960	COG2207	Transcriptional regulator
FE240_07960	COG3708	Transcriptional regulator
FE240_07965	COG3593	DNA synthesis involved in DNA repair
FE240_08015	COG1011	Hydrolase
FE240_08020	COG1473	amidohydrolase
FE240_08035	COG1643	Atp-dependent helicase
FE240_08045	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
FE240_08050	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FE240_08055	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
FE240_08060	COG0709	Synthesizes selenophosphate from selenide and ATP
FE240_08070	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
FE240_08080	COG1254	Belongs to the acylphosphatase family
FE240_08090	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FE240_08090	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FE240_08095	COG0489	protein tyrosine kinase activity
FE240_08100	COG0572	uridine kinase
FE240_08105	COG0717	Belongs to the dCTP deaminase family
FE240_08110	COG0306	phosphate transporter
FE240_08115	COG1530	ribonuclease E activity
FE240_08120	COG0564	pseudouridine synthase activity
FE240_08130	COG0424	maF-like protein
FE240_08135	COG1399	metal-binding, possibly nucleic acid-binding protein
FE240_08140	COG0333	Belongs to the bacterial ribosomal protein bL32 family
FE240_08145	COG0416	fatty acid biosynthetic process
FE240_08150	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FE240_08175	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FE240_08180	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
FE240_08185	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
FE240_08190	COG0470	DNA polymerase III
FE240_08195	COG0084	hydrolase, TatD family'
FE240_08210	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
FE240_08210	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
FE240_08215	COG3008	intermembrane lipid transfer
FE240_08220	COG2995	paraquat-inducible protein a
FE240_08230	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
FE240_08235	COG0372	Belongs to the citrate synthase family
FE240_08245	COG3141	response to X-ray
FE240_08330	COG1067	ATP-dependent peptidase activity
FE240_08335	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
FE240_08350	COG0488	(ABC) transporter
FE240_08360	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
FE240_08360	COG0116	Belongs to the methyltransferase superfamily
FE240_08370	COG0167	dihydroorotate dehydrogenase activity
FE240_08375	COG2902	Dehydrogenase
FE240_08385	COG0308	aminopeptidase N
FE240_08400	COG2501	S4 domain
FE240_08405	COG1132	(ABC) transporter
FE240_08410	COG1132	(ABC) transporter
FE240_08415	COG3118	belongs to the thioredoxin family
FE240_08420	COG0471	metal ion transport
FE240_08425	COG0058	SHG alpha-glucan phosphorylase activity
FE240_08440	COG2067	long-chain fatty acid transport protein
FE240_08445	COG0183	Belongs to the thiolase family
FE240_08460	COG3123	guanosine phosphorylase activity
FE240_08470	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FE240_08475	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
FE240_08475	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FE240_08485	COG3069	C4-dicarboxylate transmembrane transporter activity
FE240_08490	COG0737	Belongs to the 5'-nucleotidase family
FE240_08500	COG1451	nucleotide metabolic process
FE240_08515	COG3214	Protein conserved in bacteria
FE240_08520	COG2925	Exonuclease
FE240_08530	COG3345	alpha-galactosidase
FE240_08535	COG1380	Effector of murein hydrolase LrgA
FE240_08540	COG1346	cytolysis
FE240_08545	COG0295	cytidine deaminase activity
FE240_08565	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
FE240_08575	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FE240_08585	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
FE240_08595	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
FE240_08600	COG1956	GAF domain-containing protein
FE240_08615	COG3278	Belongs to the heme-copper respiratory oxidase family
FE240_08630	COG2010	Cytochrome c
FE240_08655	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FE240_08660	COG0589	response to stress
FE240_08665	COG0037	tRNA processing
FE240_08690	COG1177	transmembrane transport
FE240_08700	COG0625	glutathione transferase activity
FE240_08705	COG1869	D-ribose catabolic process
FE240_08710	COG1129	ABC transporter
FE240_08715	COG1172	Belongs to the binding-protein-dependent transport system permease family
FE240_08720	COG1879	ABC-type sugar transport system periplasmic component
FE240_08725	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FE240_08730	COG1609	Transcriptional regulator
FE240_08735	COG2199	diguanylate cyclase activity
FE240_08760	COG0784	Response regulator, receiver
FE240_08760	COG2205	protein histidine kinase activity
FE240_08765	COG0776	regulation of translation
FE240_08770	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FE240_08770	COG0072	phenylalanine-tRNA ligase activity
FE240_08775	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
FE240_08790	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
FE240_08805	COG3636	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
FE240_08855	COG0582	viral genome integration into host DNA
FE240_08880	COG0322	excinuclease ABC activity
FE240_08885	COG2197	response regulator
FE240_08890	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
FE240_08895	COG2835	tetraacyldisaccharide 4'-kinase activity
FE240_08900	COG1663	tetraacyldisaccharide 4'-kinase activity
FE240_08905	COG1132	(ABC) transporter
FE240_08910	COG2333	competence protein COMEC
FE240_08910	COG0658	competence protein
FE240_08925	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
FE240_08935	COG2062	phosphohistidine phosphatase, SixA
FE240_08945	COG0500	methyltransferase
FE240_08970	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FE240_09105	COG0582	viral genome integration into host DNA
FE240_09110	COG0518	GMP synthase (glutamine-hydrolyzing) activity
FE240_09110	COG0519	Catalyzes the synthesis of GMP from XMP
FE240_09115	COG0516	GMP reductase activity
FE240_09115	COG0517	IMP dehydrogenase activity
FE240_09125	COG0366	Alpha amylase catalytic
FE240_09125	COG1874	Beta-galactosidase
FE240_09140	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
FE240_09145	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
FE240_09150	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
FE240_09175	COG0556	nucleotide-excision repair
FE240_09185	COG0513	Belongs to the DEAD box helicase family
FE240_09190	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
FE240_09195	COG2890	protein-(glutamine-N5) methyltransferase activity
FE240_09200	COG2840	Smr protein MutS2
FE240_09220	COG2985	domain, Protein
FE240_09220	COG0569	domain protein
FE240_09230	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
FE240_09235	COG1022	Amp-dependent synthetase and ligase
FE240_09250	COG0861	Integral membrane protein TerC family
FE240_09255	COG2885	chlorophyll binding
FE240_09260	COG2199	diguanylate cyclase activity
FE240_09275	COG2154	pterin-4-alpha-carbinolamine dehydratase
FE240_09285	COG3768	UPF0283 membrane protein
FE240_09290	COG3106	COG3106 Predicted ATPase
FE240_09305	COG1842	Phage shock protein A
FE240_09310	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
FE240_09315	COG0747	negative chemotaxis
FE240_09320	COG4168	peptide transport system, permease
FE240_09325	COG4171	peptide transport system, permease
FE240_09335	COG4172	Belongs to the ABC transporter superfamily
FE240_09345	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
FE240_09350	COG1286	toxin biosynthetic process
FE240_09355	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
FE240_09360	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
FE240_09365	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
FE240_09370	COG1674	ftsk spoiiie
FE240_09370	COG0531	amino acid
FE240_09380	COG0686	Belongs to the AlaDH PNT family
FE240_09405	COG1119	ATPase activity
FE240_09410	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
FE240_09415	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
FE240_09420	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
FE240_09430	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
FE240_09435	COG1434	Gram-negative-bacterium-type cell wall biogenesis
FE240_09445	COG0205	6-phosphofructokinase activity
FE240_09455	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
FE240_09465	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
FE240_09520	COG1396	sequence-specific DNA binding
FE240_09525	COG3135	benzoate transporter
FE240_09565	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
FE240_09575	COG3477	response to acidic pH
FE240_09595	COG1785	Belongs to the alkaline phosphatase family
FE240_09615	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
FE240_09620	COG2199	diguanylate cyclase activity
FE240_09620	COG2203	Gaf domain
FE240_09625	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FE240_09630	COG0765	amino acid transport
FE240_09635	COG1126	abc transporter atp-binding protein
FE240_09640	COG0531	amino acid
FE240_09655	COG2050	protein possibly involved in aromatic compounds catabolism
FE240_09665	COG0247	lactate metabolic process
FE240_09665	COG0277	FAD linked oxidase domain protein
FE240_09675	COG1902	pentaerythritol trinitrate reductase activity
FE240_09695	COG3501	Rhs element vgr protein
FE240_09705	COG0583	DNA-binding transcription factor activity
FE240_09710	COG0733	neurotransmitter:sodium symporter activity
FE240_09720	COG0656	L-ascorbic acid biosynthetic process
FE240_09725	COG2814	Major facilitator Superfamily
FE240_09730	COG2249	NAD(P)H dehydrogenase (quinone) activity
FE240_09740	COG1294	oxidase, subunit
FE240_09745	COG1271	oxidase subunit
FE240_09750	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FE240_09755	COG2979	Protein of unknown function (DUF533)
FE240_09760	COG2979	Protein of unknown function (DUF533)
FE240_09780	COG1228	amidohydrolase
FE240_09785	COG1166	arginine decarboxylase activity
FE240_09795	COG2195	Cleaves the N-terminal amino acid of tripeptides
FE240_09800	COG0204	Acyl-transferase
FE240_09820	COG0583	DNA-binding transcription factor activity
FE240_09830	COG2759	Belongs to the formate--tetrahydrofolate ligase family
FE240_09835	COG0302	gtp cyclohydrolase
FE240_09840	COG0303	'Molybdopterin
FE240_09845	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
FE240_09855	COG2267	carboxylic ester hydrolase activity
FE240_09860	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
FE240_09875	COG0314	molybdopterin synthase activity
FE240_09880	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
FE240_09885	COG0315	cyclic pyranopterin monophosphate synthase activity
FE240_09890	COG0521	Mo-molybdopterin cofactor biosynthetic process
FE240_09895	COG3005	denitrification pathway
FE240_09905	COG0348	domain, Protein
FE240_09910	COG0437	4 iron, 4 sulfur cluster binding
FE240_09915	COG0243	molybdopterin cofactor binding
FE240_09920	COG3062	negative regulation of establishment of protein localization
FE240_09925	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
FE240_09925	COG1149	4fe-4S ferredoxin, iron-sulfur binding domain protein
FE240_09930	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
FE240_09935	COG3850	Histidine kinase
FE240_09940	COG2197	response regulator
FE240_09990	COG3132	Protein of unknown function, DUF480
FE240_10005	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
FE240_10020	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
FE240_10030	COG0562	UDP-galactopyranose mutase
FE240_10045	COG2244	polysaccharide biosynthetic process
FE240_10055	COG1028	Short-chain dehydrogenase reductase Sdr
FE240_10060	COG1083	cytidylyl-transferase
FE240_10065	COG0673	inositol 2-dehydrogenase activity
FE240_10070	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
FE240_10080	COG2089	acid synthase
FE240_10085	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
FE240_10090	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
FE240_10105	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
FE240_10105	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
FE240_10110	COG0509	glycine decarboxylation via glycine cleavage system
FE240_10115	COG0404	The glycine cleavage system catalyzes the degradation of glycine
FE240_10120	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FE240_10125	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FE240_10135	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
FE240_10145	COG2814	Major facilitator Superfamily
FE240_10150	COG0625	glutathione transferase activity
FE240_10155	COG0483	inositol monophosphate 1-phosphatase activity
FE240_10160	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
FE240_10180	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
FE240_10185	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
FE240_10190	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
FE240_10195	COG0121	glutamine amidotransferase
FE240_10200	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
FE240_10210	COG0784	Response regulator, receiver
FE240_10210	COG3437	response regulator, receiver
FE240_10220	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
FE240_10225	COG0328	RNA-DNA hybrid ribonuclease activity
FE240_10230	COG2226	methyltransferase
FE240_10235	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FE240_10240	COG1388	LysM domain
FE240_10240	COG0741	lytic transglycosylase activity
FE240_10245	COG1686	Belongs to the peptidase S11 family
FE240_10255	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
FE240_10260	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FE240_10265	COG4134	Bacterial extracellular solute-binding protein
FE240_10270	COG4135	transport system, permease component
FE240_10275	COG4136	ATPase activity
FE240_10280	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
FE240_10290	COG3634	alkyl hydroperoxide reductase activity
FE240_10295	COG3021	interspecies interaction between organisms
FE240_10305	COG1607	acyl-coa hydrolase
FE240_10310	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FE240_10330	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
FE240_10340	COG2911	Protein conserved in bacteria
FE240_10345	COG0729	surface antigen
FE240_10355	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FE240_10360	COG0417	DNA replication proofreading
FE240_10370	COG0840	transmembrane signaling receptor activity
FE240_10375	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FE240_10385	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
FE240_10390	COG0563	adenylate kinase activity
FE240_10395	COG0326	Molecular chaperone. Has ATPase activity
FE240_10400	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
FE240_10425	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
FE240_10430	COG2832	Protein of unknown function (DUF454)
FE240_10435	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
FE240_10445	COG0697	spore germination
FE240_10460	COG0318	PFAM AMP-dependent synthetase and ligase
FE240_10470	COG3065	identical protein binding
FE240_10475	COG1214	PFAM Peptidase M22, glycoprotease
FE240_10480	COG1199	ATP-dependent helicase activity
FE240_10490	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
FE240_10495	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
FE240_10500	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
FE240_10505	COG0131	Imidazoleglycerol-phosphate dehydratase
FE240_10505	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
FE240_10510	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
FE240_10515	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
FE240_10520	COG0107	imidazoleglycerol-phosphate synthase activity
FE240_10525	COG0140	phosphoribosyl-ATP diphosphatase activity
FE240_10525	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
FE240_10540	COG2951	lytic endotransglycosylase activity
FE240_10545	COG1435	thymidine kinase activity
FE240_10550	COG1757	Na H antiporter
FE240_10555	COG2916	Histone family protein nucleoid-structuring protein H-NS
FE240_10560	COG2096	Adenosyltransferase
FE240_10565	COG3530	Putative quorum-sensing-regulated virulence factor
FE240_10570	COG0602	queuosine metabolic process
FE240_10575	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
FE240_10595	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
FE240_10605	COG0776	regulation of translation
FE240_10610	COG0539	negative regulation of cytoplasmic translation
FE240_10615	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
FE240_10620	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FE240_10625	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
FE240_10640	COG5377	YqaJ viral recombinase family
FE240_10745	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
FE240_10810	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FE240_10820	COG1242	4 iron, 4 sulfur cluster binding
FE240_10825	COG0067	glutamate synthase
FE240_10825	COG0070	glutamate synthase
FE240_10825	COG0069	glutamate synthase activity
FE240_10830	COG0493	'glutamate synthase
FE240_10850	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
FE240_10860	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FE240_10880	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FE240_10885	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
FE240_10890	COG2188	Transcriptional regulator
FE240_10895	COG1840	ABC-type Fe3 transport system, periplasmic component
FE240_10900	COG3842	ATPase activity
FE240_10910	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FE240_10910	COG0301	tRNA thio-modification
FE240_10930	COG5001	Diguanylate cyclase
FE240_10930	COG3300	MHYT domain
FE240_10935	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
FE240_10965	COG2431	L-lysine efflux transmembrane transporter activity
FE240_10970	COG1301	dicarboxylic acid transport
FE240_10980	COG3724	N-succinylarginine dihydrolase activity
FE240_10985	COG0616	signal peptide processing
FE240_10990	COG1028	Short-chain dehydrogenase reductase Sdr
FE240_10995	COG0583	DNA-binding transcription factor activity
FE240_11005	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
FE240_11020	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
FE240_11025	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
FE240_11040	COG0659	secondary active sulfate transmembrane transporter activity
FE240_11105	COG0582	viral genome integration into host DNA
FE240_11115	COG2314	TM2 domain
FE240_11130	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FE240_11130	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FE240_11165	COG1278	Cold shock
FE240_11185	COG0586	Pfam SNARE associated Golgi protein
FE240_11215	COG0840	transmembrane signaling receptor activity
FE240_11225	COG3706	GGDEF domain
FE240_11235	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
FE240_11245	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
FE240_11255	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
FE240_11260	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
FE240_11265	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FE240_11295	COG0601	transmembrane transport
FE240_11300	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FE240_11305	COG0444	Belongs to the ABC transporter superfamily
FE240_11310	COG4608	Belongs to the ABC transporter superfamily
FE240_11320	COG2971	BadF BadG BcrA BcrD
FE240_11335	COG0840	transmembrane signaling receptor activity
FE240_11340	COG0840	transmembrane signaling receptor activity
FE240_11350	COG2020	methyltransferase activity
FE240_11355	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
FE240_11360	COG0861	Integral membrane protein TerC family
FE240_11375	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FE240_11380	COG0601	transmembrane transport
FE240_11390	COG2095	MarC family integral membrane protein
FE240_11395	COG1012	belongs to the aldehyde dehydrogenase family
FE240_11395	COG1454	alcohol dehydrogenase
FE240_11405	COG0217	transcriptional regulatory protein
FE240_11410	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
FE240_11420	COG1801	Protein of unknown function DUF72
FE240_11425	COG4106	trans-aconitate 2-methyltransferase activity
FE240_11430	COG0500	methyltransferase
FE240_11450	COG0583	DNA-binding transcription factor activity
FE240_11455	COG2233	PERMEase
FE240_11460	COG0281	malic enzyme
FE240_11490	COG1032	radical SAM domain protein
FE240_11515	COG2199	diguanylate cyclase activity
FE240_11520	COG1752	Esterase of the alpha-beta hydrolase superfamily
FE240_11540	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
FE240_11540	COG2885	chlorophyll binding
FE240_11550	COG2914	Belongs to the UPF0125 (RnfH) family
FE240_11555	COG2867	negative regulation of translational initiation
FE240_11560	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
FE240_11620	COG0814	amino acid
FE240_11625	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
FE240_11630	COG1982	Orn Lys Arg decarboxylase major
FE240_11635	COG0531	amino acid
FE240_11640	COG3710	Transcriptional regulator
FE240_11645	COG0825	malonyl-CoA metabolic process
FE240_11655	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
FE240_11660	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FE240_11665	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FE240_11670	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
FE240_11675	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FE240_11690	COG0750	zinc metalloprotease
FE240_11695	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
FE240_11700	COG0575	Belongs to the CDS family
FE240_11705	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
FE240_11710	COG0233	cytoplasmic translational termination
FE240_11715	COG0528	UMP kinase activity
FE240_11720	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
FE240_11725	COG0052	Belongs to the universal ribosomal protein uS2 family
FE240_11730	COG0024	Methionine aminopeptidase
FE240_11735	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
FE240_11740	COG2171	N-acyltransferase activity
FE240_11750	COG1263	PTS System
FE240_11750	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FE240_11760	COG4580	involved in the transport of maltose and maltodextrins
FE240_11765	COG0281	malic enzyme
FE240_11770	COG2207	Transcriptional regulator
FE240_11775	COG0534	Mate efflux family protein
FE240_11795	COG1115	amino acid carrier protein
FE240_11800	COG0019	diaminopimelate decarboxylase activity
FE240_11810	COG0678	peroxiredoxin activity
FE240_11820	COG1126	abc transporter atp-binding protein
FE240_11825	COG0765	amino acid transport
FE240_11830	COG4597	amino acid ABC transporter
FE240_11835	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FE240_11850	COG0545	Peptidyl-prolyl cis-trans isomerase
FE240_11860	COG1940	carbohydrate kinase activity
FE240_11880	COG5002	protein histidine kinase activity
FE240_11885	COG0745	RESPONSE REGULATOR receiver
FE240_11895	COG0300	oxidoreductase activity
FE240_11910	COG2840	Smr protein MutS2
FE240_11915	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
FE240_11940	COG0419	ATPase involved in DNA repair
FE240_11945	COG0420	3'-5' exonuclease activity
FE240_11955	COG2974	May be involved in recombination
FE240_11965	COG0583	DNA-binding transcription factor activity
FE240_11985	COG1263	PTS System
FE240_11985	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FE240_11990	COG1874	Beta-galactosidase
FE240_11995	COG3867	Arabinogalactan endo-beta-1,4-galactanase
FE240_12000	COG3833	ABC-type maltose transport systems, permease component
FE240_12005	COG1175	transmembrane transport
FE240_12010	COG2182	Extracellular solute-binding protein
FE240_12035	COG4580	involved in the transport of maltose and maltodextrins
FE240_12040	COG1609	Transcriptional regulator
FE240_12045	COG0826	peptidase U32
FE240_12050	COG1280	lysine exporter protein (LysE YggA)
FE240_12060	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FE240_12100	COG0534	Mate efflux family protein
FE240_12125	COG0300	oxidoreductase activity
FE240_12140	COG0642	Histidine kinase
FE240_12150	COG0674	pyruvate-flavodoxin oxidoreductase activity
FE240_12150	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
FE240_12150	COG1013	pyruvate-flavodoxin oxidoreductase activity
FE240_12150	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
FE240_12155	COG0493	'glutamate synthase
FE240_12160	COG3217	Mosc domain protein beta barrel domain protein
FE240_12160	COG0633	Ferredoxin
FE240_12160	COG3217	Mosc domain protein beta barrel domain protein
FE240_12160	COG0633	Ferredoxin
FE240_12165	COG0501	Belongs to the peptidase M48B family
FE240_12170	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
FE240_12175	COG2226	methyltransferase
FE240_12180	COG0156	8-amino-7-oxononanoate synthase activity
FE240_12185	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
FE240_12200	COG0017	Asparaginyl-tRNA synthetase
FE240_12205	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
FE240_12215	COG2199	diguanylate cyclase activity
FE240_12225	COG3590	peptidase
FE240_12245	COG3098	single-species biofilm formation
FE240_12270	COG5595	Zn-ribbon-containing, possibly nucleic-acid-binding protein (DUF2310)
FE240_12285	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
FE240_12285	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
FE240_12300	COG1611	Belongs to the LOG family
FE240_12305	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FE240_12310	COG0473	3-isopropylmalate dehydrogenase activity
FE240_12320	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
FE240_12335	COG0583	DNA-binding transcription factor activity
FE240_12340	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
FE240_12355	COG2991	Protein conserved in bacteria
FE240_12360	COG1477	protein flavinylation
FE240_12370	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
FE240_12375	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
FE240_12380	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
FE240_12385	COG1805	sodium ion transport
FE240_12395	COG0271	Belongs to the BolA IbaG family
FE240_12405	COG2813	Specifically methylates the guanine in position
FE240_12420	COG2211	Major facilitator Superfamily
FE240_12425	COG3248	Nucleoside-binding outer membrane protein
FE240_12430	COG1666	GTP binding
FE240_12435	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
FE240_12460	COG0633	Ferredoxin
FE240_12465	COG0443	Heat shock 70 kDa protein
FE240_12470	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
FE240_12480	COG0822	iron-sulfur transferase activity
FE240_12485	COG1104	cysteine desulfurase activity
FE240_12490	COG1959	2 iron, 2 sulfur cluster binding
FE240_12505	COG3154	lipid carrier protein
FE240_12510	COG0826	peptidase U32
FE240_12515	COG0826	peptidase U32
FE240_12525	COG2897	thiosulfate sulfurtransferase activity
FE240_12530	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FE240_12535	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FE240_12540	COG1862	Preprotein translocase
FE240_12545	COG0343	queuine tRNA-ribosyltransferase activity
FE240_12550	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
FE240_12555	COG0517	IMP dehydrogenase activity
FE240_12570	COG1393	Belongs to the ArsC family
FE240_12580	COG4783	chaperone-mediated protein folding
FE240_12585	COG0425	Belongs to the sulfur carrier protein TusA family
FE240_12605	COG3842	ATPase activity
FE240_12610	COG3833	ABC-type maltose transport systems, permease component
FE240_12615	COG1175	transmembrane transport
FE240_12625	COG3081	Nucleoid-associated protein
FE240_12630	COG3082	Protein of unknown function (DUF1414)
FE240_12645	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
FE240_12650	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
FE240_12655	COG1151	hydroxylamine reductase activity
FE240_12660	COG0783	Belongs to the Dps family
FE240_12670	COG0789	Transcriptional regulator
FE240_12675	COG3272	Protein of unknown function (DUF1722)
FE240_12700	COG1605	Chorismate mutase
FE240_12700	COG0077	Prephenate dehydratase
FE240_12735	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FE240_12800	COG2814	Major facilitator Superfamily
FE240_12805	COG0109	protoheme IX farnesyltransferase activity
FE240_12810	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
FE240_12815	COG1845	cytochrome c oxidase, subunit III
FE240_12820	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
FE240_12825	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
FE240_12830	COG3152	Membrane
FE240_12850	COG1442	glycosyl transferase family 8
FE240_12875	COG0438	transferase activity, transferring glycosyl groups
FE240_12895	COG0489	protein tyrosine kinase activity
FE240_12895	COG3206	protein involved in exopolysaccharide biosynthesis
FE240_12935	COG2375	cellular response to nickel ion
FE240_12945	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
FE240_12950	COG2200	EAL domain
FE240_12955	COG0071	Belongs to the small heat shock protein (HSP20) family
FE240_12960	COG0545	Peptidyl-prolyl cis-trans isomerase
FE240_12965	COG4771	TonB-dependent receptor
FE240_12970	COG0741	lytic transglycosylase activity
FE240_12980	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
FE240_12990	COG0697	spore germination
FE240_12995	COG4565	transcriptional regulatory protein
FE240_13000	COG3290	protein histidine kinase activity
FE240_13025	COG4608	Belongs to the ABC transporter superfamily
FE240_13030	COG0444	Belongs to the ABC transporter superfamily
FE240_13040	COG4239	(ABC) transporter, permease
FE240_13045	COG4174	ABC transporter (Permease)
FE240_13050	COG4206	TonB-dependent receptor
FE240_13060	COG0811	peptide transport
FE240_13065	COG0811	peptide transport
FE240_13070	COG0848	biopolymer transport protein
FE240_13085	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
FE240_13090	COG2011	ABC-type metal ion transport system permease component
FE240_13095	COG1464	Belongs to the NlpA lipoprotein family
FE240_13115	COG2198	Histidine kinase
FE240_13115	COG0784	Response regulator, receiver
FE240_13115	COG5002	protein histidine kinase activity
FE240_13125	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FE240_13130	COG0191	fructose-bisphosphate aldolase activity
FE240_13135	COG0126	phosphoglycerate kinase activity
FE240_13140	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
FE240_13145	COG1940	carbohydrate kinase activity
FE240_13150	COG0545	Peptidyl-prolyl cis-trans isomerase
FE240_13160	COG2900	Belongs to the SlyX family
FE240_13165	COG1047	Peptidyl-prolyl cis-trans
FE240_13170	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
FE240_13180	COG0835	chemotaxis
FE240_13180	COG0784	Response regulator, receiver
FE240_13185	COG0429	hydrolase of the alpha beta-hydrolase fold
FE240_13190	COG3706	GGDEF domain
FE240_13190	COG5001	Diguanylate cyclase
FE240_13190	COG2203	Gaf domain
FE240_13190	COG4251	negative regulation of phosphorylation
FE240_13200	COG3089	Belongs to the UPF0270 family
FE240_13205	COG3954	Phosphoribulokinase
FE240_13220	COG1765	OsmC-like protein
FE240_13230	COG2226	methyltransferase
FE240_13235	COG4221	oxidoreductase activity
FE240_13250	COG1024	Enoyl-CoA hydratase
FE240_13260	COG4166	transmembrane transport
FE240_13270	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
FE240_13285	COG1278	Cold shock
FE240_13310	COG0737	Belongs to the 5'-nucleotidase family
FE240_13330	COG2204	response regulator
FE240_13350	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
FE240_13360	COG3091	SprT-like family
FE240_13370	COG1385	rRNA (uridine-N3-)-methyltransferase activity
FE240_13375	COG0189	ligase activity
FE240_13380	COG1678	Uncharacterized ACR, COG1678
FE240_13385	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
FE240_13420	COG3188	usher protein
FE240_13425	COG3121	Chaperone
FE240_13435	COG1115	amino acid carrier protein
FE240_13440	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
FE240_13455	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
FE240_13460	COG3445	Acts as a radical domain for damaged PFL and possibly other radical proteins
FE240_13465	COG0148	phosphopyruvate hydratase activity
FE240_13470	COG0504	CTP synthase activity
FE240_13475	COG3956	TIGRFAM MazG family protein
FE240_13480	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
FE240_13485	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
FE240_13495	COG4807	Protein conserved in bacteria
FE240_13500	COG3023	N-Acetylmuramoyl-L-alanine amidase
FE240_13505	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
FE240_13510	COG1381	Involved in DNA repair and RecF pathway recombination
FE240_13520	COG0571	ribonuclease III activity
FE240_13530	COG0481	GTPase activity
FE240_13540	COG3026	antisigma factor binding
FE240_13550	COG1595	DNA-templated transcription, initiation
FE240_13555	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
FE240_13565	COG0114	fumarate hydratase activity
FE240_13575	COG0432	Pfam Uncharacterised protein family UPF0047
FE240_13580	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
FE240_13595	COG3150	esterase
FE240_13610	COG0494	nUDIX hydrolase
FE240_13615	COG1538	Outer membrane efflux protein
FE240_13630	COG1842	Phage shock protein A
FE240_13635	COG0204	Acyl-transferase
FE240_13650	COG0583	DNA-binding transcription factor activity
FE240_13655	COG4221	oxidoreductase activity
FE240_13680	COG2329	Antibiotic biosynthesis monooxygenase
FE240_13690	COG1051	belongs to the nudix hydrolase family
FE240_13705	COG0354	folic acid binding
FE240_13725	COG1324	tolerance protein
FE240_13730	COG4232	protein-disulfide reductase activity
FE240_13740	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
FE240_13745	COG2816	NAD+ diphosphatase activity
FE240_13765	COG3022	response to hydroperoxide
FE240_13780	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
FE240_13785	COG0762	integral membrane protein
FE240_13790	COG1872	DUF167
FE240_13805	COG0776	regulation of translation
FE240_13815	COG4942	peptidase
FE240_13815	COG1388	LysM domain
FE240_13820	COG1238	metal cluster binding
FE240_13825	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
FE240_13830	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
FE240_13835	COG0585	pseudouridine synthase activity
FE240_13845	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
FE240_13850	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
FE240_13855	COG1301	dicarboxylic acid transport
FE240_13860	COG2877	3-deoxy-8-phosphooctulonate synthase activity
FE240_13865	COG2912	Transglutaminase-like superfamily
FE240_13875	COG2890	protein-(glutamine-N5) methyltransferase activity
FE240_13880	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
FE240_13885	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
FE240_13890	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
FE240_13895	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
FE240_13900	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
FE240_13905	COG0193	aminoacyl-tRNA hydrolase activity
FE240_13910	COG0012	GTP binding
FE240_13920	COG5377	YqaJ viral recombinase family
FE240_13970	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
FE240_13975	COG0732	type I restriction modification DNA specificity domain
FE240_14005	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
FE240_14010	COG1204	response to ionizing radiation
FE240_14085	COG0490	domain, Protein
FE240_14085	COG0471	metal ion transport
FE240_14090	COG1049	propionate catabolic process, 2-methylcitrate cycle
FE240_14095	COG1752	Esterase of the alpha-beta hydrolase superfamily
FE240_14105	COG3706	GGDEF domain
FE240_14110	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FE240_14115	COG0508	dehydrogenase complex catalyzes the overall conversion of
FE240_14120	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
FE240_14125	COG2186	Transcriptional regulator
FE240_14150	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
FE240_14170	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
FE240_14175	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
FE240_14180	COG0494	nUDIX hydrolase
FE240_14185	COG0653	protein targeting
FE240_14195	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
FE240_14200	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
FE240_14205	COG0849	cell division
FE240_14215	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
FE240_14220	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
FE240_14225	COG0772	Belongs to the SEDS family
FE240_14230	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
FE240_14235	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
FE240_14240	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
FE240_14245	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
FE240_14255	COG3116	cell division
FE240_14260	COG0275	rRNA processing
FE240_14265	COG2001	Belongs to the MraZ family
FE240_14275	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
FE240_14280	COG3107	peptidoglycan biosynthetic process
FE240_14285	COG0792	nuclease activity
FE240_14290	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
FE240_14295	COG2823	Periplasmic or secreted lipoprotein
FE240_14300	COG2969	positive regulation of protein catabolic process
FE240_14305	COG0625	glutathione transferase activity
FE240_14310	COG2857	Cytochrome c1
FE240_14315	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
FE240_14320	COG0723	plastoquinol--plastocyanin reductase activity
FE240_14325	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
FE240_14330	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
FE240_14335	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
FE240_14345	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FE240_14350	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FE240_14355	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
FE240_14360	COG1660	Displays ATPase and GTPase activities
FE240_14365	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FE240_14370	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
FE240_14375	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
FE240_14380	COG1137	ATPase activity
FE240_14385	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
FE240_14395	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
FE240_14400	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
FE240_14400	COG0517	IMP dehydrogenase activity
FE240_14405	COG1127	ABC transporter
FE240_14410	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
FE240_14415	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
FE240_14420	COG2854	intermembrane phospholipid transfer
FE240_14430	COG5007	Belongs to the BolA IbaG family
FE240_14435	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
FE240_14440	COG0312	modulator of DNA gyrase
FE240_14445	COG3028	Belongs to the UPF0307 family
FE240_14455	COG0477	Major facilitator Superfamily
FE240_14465	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
FE240_14470	COG0359	binds to the 23S rRNA
FE240_14475	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
FE240_14480	COG0360	Binds together with S18 to 16S ribosomal RNA
FE240_14485	COG1914	H( )-stimulated, divalent metal cation uptake system
FE240_14530	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
FE240_14535	COG0583	DNA-binding transcription factor activity
FE240_14540	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
FE240_14555	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
FE240_14565	COG1970	mechanosensitive ion channel activity
FE240_14570	COG4974	Belongs to the 'phage' integrase family
FE240_14575	COG0716	FMN binding
FE240_14595	COG1376	ErfK ybiS ycfS ynhG family protein
FE240_14635	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
FE240_14640	COG0527	aspartate kinase activity
FE240_14645	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
FE240_14650	COG2137	regulation of response to DNA damage stimulus
FE240_14655	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
FE240_14660	COG1546	Belongs to the CinA family
FE240_14720	COG3039	Transposase
FE240_14745	COG2916	Histone family protein nucleoid-structuring protein H-NS
FE240_14765	COG0582	viral genome integration into host DNA
FE240_14770	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
FE240_14790	COG3068	Protein conserved in bacteria
FE240_14800	COG0312	modulator of DNA gyrase
FE240_14805	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FE240_14815	COG3164	Protein of unknown function
FE240_14820	COG1530	ribonuclease E activity
FE240_14825	COG0424	maF-like protein
FE240_14830	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
FE240_14835	COG1792	Involved in formation and maintenance of cell shape
FE240_14840	COG1077	Cell shape determining protein MreB Mrl
FE240_14870	COG2165	general secretion pathway protein
FE240_14875	COG2165	general secretion pathway protein
FE240_14885	COG1459	type II secretion system
FE240_14890	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
FE240_14900	COG3267	Type II secretory pathway component ExeA
FE240_14900	COG3409	Peptidoglycan-binding domain 1 protein
FE240_14940	COG0741	lytic transglycosylase activity
FE240_14940	COG1388	LysM domain
FE240_14955	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
FE240_14960	COG1191	sigma factor activity
FE240_14985	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
FE240_15000	COG1706	bacterial-type flagellum-dependent cell motility
FE240_15005	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
FE240_15010	COG4786	Flagellar basal body rod
FE240_15020	COG1749	Flagellar hook protein flgE
FE240_15030	COG1558	bacterial-type flagellum-dependent cell motility
FE240_15035	COG1815	bacterial-type flagellum-dependent cell motility
FE240_15090	COG1677	Flagellar hook-basal body complex protein FliE
FE240_15115	COG1987	bacterial-type flagellum assembly
FE240_15135	COG3842	ATPase activity
FE240_15145	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FE240_15160	COG1773	rubredoxin
FE240_15165	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
FE240_15170	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
FE240_15175	COG5557	Pfam Polysulphide reductase, NrfD
FE240_15180	COG0437	4 iron, 4 sulfur cluster binding
FE240_15185	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
FE240_15190	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
FE240_15195	COG0375	protein maturation
FE240_15210	COG0298	carbon dioxide binding
FE240_15215	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
FE240_15225	COG1349	DNA-binding transcription factor activity
FE240_15235	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
FE240_15245	COG0840	transmembrane signaling receptor activity
FE240_15250	COG4991	sh3 domain protein
FE240_15260	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
FE240_15265	COG0828	Belongs to the bacterial ribosomal protein bS21 family
FE240_15270	COG1610	YqeY-like protein
FE240_15275	COG0358	DNA primase activity
FE240_15280	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
FE240_15300	COG0542	response to heat
FE240_15305	COG2502	aspartate--ammonia ligase
FE240_15310	COG1522	sequence-specific DNA binding
FE240_15320	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
FE240_15325	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
FE240_15330	COG1979	alcohol dehydrogenase
FE240_15335	COG2207	Transcriptional regulator
FE240_15350	COG0540	Belongs to the ATCase OTCase family
FE240_15355	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
FE240_15360	COG1438	arginine binding
FE240_15380	COG0671	phosphoesterase, PA-phosphatase related
FE240_15385	COG0628	permease
FE240_15390	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
FE240_15390	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
FE240_15390	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
FE240_15395	COG1461	Dihydroxyacetone kinase
FE240_15400	COG2376	Dihydroxyacetone kinase
FE240_15405	COG2252	PERMEase
FE240_15425	COG3112	Uncharacterised protein family (UPF0231)
FE240_15430	COG1929	Belongs to the glycerate kinase type-1 family
FE240_15450	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
FE240_15465	COG2926	Belongs to the UPF0265 family
FE240_15505	COG1902	pentaerythritol trinitrate reductase activity
FE240_15525	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
FE240_15545	COG1357	PFAM Pentapeptide repeats (8 copies)
FE240_15610	COG0488	(ABC) transporter
FE240_15705	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
FE240_15760	COG5642	Protein of unknown function (DUF2384)
FE240_15765	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
FE240_15790	COG4974	Belongs to the 'phage' integrase family
FE240_15830	COG1575	Belongs to the MenA family. Type 1 subfamily
FE240_15835	COG1169	isochorismate synthase
FE240_15840	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
FE240_15850	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
FE240_15855	COG1441	menaquinone biosynthetic process
FE240_15865	COG2949	membrane
FE240_15880	COG3047	cAMP biosynthetic process
FE240_15885	COG3706	GGDEF domain
FE240_15890	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
FE240_15900	COG2771	luxR family
FE240_15905	COG3916	Acyl-homoserine-lactone synthase
FE240_15910	COG1733	regulation of RNA biosynthetic process
FE240_15950	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
FE240_15955	COG1047	Peptidyl-prolyl cis-trans
FE240_15960	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
FE240_15965	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
FE240_15970	COG0196	riboflavin kinase activity
FE240_15975	COG0728	peptidoglycan biosynthetic process
FE240_15980	COG0268	Binds directly to 16S ribosomal RNA
FE240_15985	COG0640	Transcriptional regulator
FE240_15990	COG0583	DNA-binding transcription factor activity
FE240_15995	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
FE240_16000	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
FE240_16005	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
FE240_16015	COG1051	belongs to the nudix hydrolase family
FE240_16020	COG3066	DNA modification
FE240_16030	COG0335	large ribosomal subunit rRNA binding
FE240_16035	COG0336	Belongs to the RNA methyltransferase TrmD family
FE240_16040	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
FE240_16045	COG0228	four-way junction DNA binding
FE240_16050	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
FE240_16055	COG4137	Cytochrome C assembly protein
FE240_16060	COG4536	flavin adenine dinucleotide binding
FE240_16070	COG1017	nitric oxide dioxygenase activity
FE240_16070	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
FE240_16075	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
FE240_16080	COG0039	L-malate dehydrogenase activity
FE240_16085	COG4160	amino acid transport
FE240_16090	COG4215	(ABC) transporter
FE240_16095	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FE240_16100	COG1126	abc transporter atp-binding protein
FE240_16105	COG1438	arginine binding
FE240_16110	COG2837	iron assimilation
FE240_16115	COG3842	ATPase activity
FE240_16125	COG1840	ABC-type Fe3 transport system, periplasmic component
FE240_16130	COG0347	Belongs to the P(II) protein family
FE240_16175	COG3118	belongs to the thioredoxin family
FE240_16175	COG0457	Tetratricopeptide repeat
FE240_16180	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
FE240_16190	COG1215	transferase activity, transferring glycosyl groups
FE240_16205	COG2194	sulfuric ester hydrolase activity
FE240_16210	COG1448	Aminotransferase
FE240_16220	COG0840	transmembrane signaling receptor activity
FE240_16260	COG1522	sequence-specific DNA binding
FE240_16275	COG3005	denitrification pathway
FE240_16280	COG0243	molybdopterin cofactor binding
FE240_16290	COG4771	TonB-dependent receptor
FE240_16305	COG0006	proline dipeptidase activity
FE240_16315	COG3133	Outer membrane lipoprotein
FE240_16325	COG0561	phosphatase activity
FE240_16330	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
FE240_16350	COG0513	Belongs to the DEAD box helicase family
FE240_16360	COG1403	HNH endonuclease
FE240_16365	COG0189	ligase activity
FE240_16380	COG1218	3'(2'),5'-bisphosphate nucleotidase
FE240_16385	COG0494	nUDIX hydrolase
FE240_16395	COG1011	Hydrolase
FE240_16400	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
FE240_16415	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
FE240_16420	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FE240_16430	COG3078	GTPase activator activity
FE240_16440	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
FE240_16445	COG0408	coproporphyrinogen oxidase activity
FE240_16450	COG0009	L-threonylcarbamoyladenylate synthase
FE240_16455	COG0551	DNA topoisomerase type I activity
FE240_16460	COG2922	Belongs to the Smg family
FE240_16465	COG0758	DNA mediated transformation
FE240_16475	COG0242	peptide deformylase activity
FE240_16480	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
FE240_16485	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
FE240_16485	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
FE240_16490	COG0569	domain protein
FE240_16495	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
FE240_16500	COG1322	Protein conserved in bacteria
FE240_16520	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FE240_16525	COG0583	DNA-binding transcription factor activity
FE240_16530	COG0518	GMP synthase (glutamine-hydrolyzing) activity
FE240_16530	COG0519	Catalyzes the synthesis of GMP from XMP
FE240_16535	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
FE240_16540	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
FE240_16540	COG0662	Cupin 2, conserved barrel domain protein
FE240_16545	COG1012	belongs to the aldehyde dehydrogenase family
FE240_16595	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FE240_16600	COG0210	DNA helicase
FE240_16605	COG0842	Transport permease protein
FE240_16610	COG0842	Transport permease protein
FE240_16615	COG1131	(ABC) transporter
FE240_16620	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FE240_16630	COG0583	DNA-binding transcription factor activity
FE240_16650	COG4776	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction
FE240_16660	COG0018	arginyl-trna synthetase
FE240_16670	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
FE240_16675	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
FE240_16680	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FE240_16690	COG2116	formate transmembrane transporter activity
FE240_16695	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
FE240_16695	COG1648	precorrin-2 dehydrogenase activity
FE240_16700	COG2239	Acts as a magnesium transporter
FE240_16715	COG0438	transferase activity, transferring glycosyl groups
FE240_16720	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FE240_16725	COG0438	transferase activity, transferring glycosyl groups
FE240_16735	COG1309	transcriptional regulator
FE240_16745	COG1063	alcohol dehydrogenase
FE240_16750	COG0840	transmembrane signaling receptor activity
FE240_16760	COG1129	ABC transporter
FE240_16770	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
FE240_16775	COG1085	galactose-1-phosphate uridylyltransferase
FE240_16780	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
FE240_16785	COG2017	converts alpha-aldose to the beta-anomer
FE240_16790	COG1968	undecaprenyl-diphosphatase activity
FE240_16795	COG0561	phosphatase activity
FE240_16820	COG1309	transcriptional regulator
FE240_16825	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FE240_16830	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FE240_16835	COG3245	cytochrome
FE240_16840	COG3706	GGDEF domain
FE240_16840	COG4251	negative regulation of phosphorylation
FE240_16840	COG2203	Gaf domain
FE240_16840	COG5001	Diguanylate cyclase
FE240_16845	COG0210	DNA helicase
FE240_16850	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
FE240_16855	COG2166	iron-sulfur cluster assembly
FE240_16865	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
FE240_16870	COG1368	sulfuric ester hydrolase activity
FE240_16875	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
FE240_16880	COG3706	GGDEF domain
FE240_16885	COG3263	regulation of cellular component size
FE240_16890	COG0484	heat shock protein binding
FE240_16910	COG1671	Belongs to the UPF0178 family
FE240_16920	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
FE240_16930	COG1494	fructose-1,6-bisphosphatase
FE240_16940	COG0288	reversible hydration of carbon dioxide
FE240_16950	COG2177	Part of the ABC transporter FtsEX involved in
FE240_16955	COG2884	Cell division ATP-binding protein ftsE
FE240_16960	COG0552	protein localization to endoplasmic reticulum
FE240_16965	COG0742	ribosomal rna small subunit methyltransferase
FE240_16985	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FE240_17000	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
FE240_17010	COG2095	MarC family integral membrane protein
FE240_17020	COG1301	dicarboxylic acid transport
FE240_17030	COG0583	DNA-binding transcription factor activity
FE240_17055	COG0203	ribosomal protein L17
FE240_17060	COG0202	RNA polymerase activity
FE240_17065	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
FE240_17070	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
FE240_17075	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
FE240_17080	COG0257	Belongs to the bacterial ribosomal protein bL36 family
FE240_17085	COG0201	protein transport
FE240_17090	COG0200	Binds to the 23S rRNA
FE240_17095	COG1841	ribosomal large subunit assembly
FE240_17100	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
FE240_17105	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
FE240_17110	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
FE240_17115	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
FE240_17120	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
FE240_17125	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
FE240_17130	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
FE240_17135	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
FE240_17140	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
FE240_17145	COG0255	Belongs to the universal ribosomal protein uL29 family
FE240_17150	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
FE240_17155	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
FE240_17160	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
FE240_17165	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
FE240_17170	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
FE240_17175	COG0089	rRNA binding
FE240_17180	COG0088	Forms part of the polypeptide exit tunnel
FE240_17185	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
FE240_17190	COG0051	transcription antitermination factor activity, RNA binding
FE240_17210	COG0165	Argininosuccinate lyase
FE240_17215	COG0137	argininosuccinate synthase activity
FE240_17225	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
FE240_17230	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
FE240_17240	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
FE240_17270	COG1380	Effector of murein hydrolase LrgA
FE240_17275	COG1346	cytolysis
FE240_17285	COG0583	DNA-binding transcription factor activity
FE240_17290	COG0527	aspartate kinase activity
FE240_17290	COG0460	homoserine dehydrogenase
FE240_17295	COG0626	cystathionine gamma-synthase activity
FE240_17305	COG0814	amino acid
FE240_17315	COG2358	TRAP transporter, solute receptor (TAXI family
FE240_17320	COG2885	chlorophyll binding
FE240_17330	COG2818	Glycosylase
FE240_17335	COG0752	glycyl-tRNA synthetase alpha subunit
FE240_17340	COG0751	glycine-tRNA ligase activity
FE240_17355	COG0814	amino acid
FE240_17360	COG0348	domain, Protein
FE240_17365	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
FE240_17365	COG2226	methyltransferase
FE240_17365	COG0596	Alpha beta hydrolase
FE240_17375	COG0446	pyridine nucleotide-disulphide oxidoreductase
FE240_17380	COG0426	domain, Protein
FE240_17380	COG1773	rubredoxin
FE240_17385	COG3604	Transcriptional regulator
FE240_17390	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
FE240_17410	COG0683	leucine binding
FE240_17445	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FE240_17455	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
FE240_17465	COG1580	Controls the rotational direction of flagella during chemotaxis
FE240_17480	COG1519	Transferase
FE240_17485	COG0859	PFAM glycosyl transferase family 9
FE240_17520	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
FE240_17525	COG0848	biopolymer transport protein
FE240_17530	COG0811	peptide transport
FE240_17535	COG0811	peptide transport
FE240_17545	COG2771	luxR family
FE240_17605	COG2205	protein histidine kinase activity
FE240_17610	COG0745	RESPONSE REGULATOR receiver
FE240_17620	COG3977	Valine--pyruvate aminotransferase
FE240_17625	COG0071	Belongs to the small heat shock protein (HSP20) family
FE240_17645	COG0592	DNA-directed DNA polymerase activity
FE240_17650	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
FE240_17665	COG1126	abc transporter atp-binding protein
FE240_17670	COG0230	Belongs to the bacterial ribosomal protein bL34 family
FE240_17675	COG0594	ribonuclease P activity
FE240_17680	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
FE240_17685	COG0706	membrane insertase activity
FE240_17690	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
FE240_17695	COG4974	Belongs to the 'phage' integrase family
FE240_17730	COG3012	SEC-C Motif Domain Protein
FE240_17730	COG3318	Belongs to the UPF0149 family
FE240_17740	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
FE240_17775	COG3550	peptidyl-serine autophosphorylation
FE240_17785	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FE240_17790	COG1120	ATPase activity
FE240_17795	COG4615	Cyclic peptide transporter
FE240_17800	COG4774	siderophore transport
FE240_17805	COG0716	FMN binding
FE240_17810	COG0445	tRNA wobble uridine modification
FE240_17815	COG0357	Ribosomal RNA small subunit methyltransferase G
FE240_17820	COG1192	Involved in chromosome partitioning
FE240_17825	COG1475	DNA binding
FE240_17835	COG0356	it plays a direct role in the translocation of protons across the membrane
FE240_17845	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
FE240_17850	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
FE240_17855	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
FE240_17860	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
FE240_17865	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
FE240_17870	COG0355	proton-transporting ATP synthase activity, rotational mechanism
FE240_17875	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
FE240_17890	COG1902	pentaerythritol trinitrate reductase activity
FE240_17940	COG1196	nuclear chromosome segregation
FE240_18010	COG3093	addiction module antidote protein HigA
FE240_18015	COG3549	Plasmid maintenance system killer
FE240_18025	COG1561	YicC-like family, N-terminal region
FE240_18035	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
FE240_18040	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
FE240_18050	COG0248	Ppx GppA phosphatase
FE240_18055	COG0513	Belongs to the DEAD box helicase family
FE240_18060	COG3118	belongs to the thioredoxin family
FE240_18075	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
FE240_18085	COG5001	Diguanylate cyclase
FE240_18090	COG2960	long-chain fatty acid transporting porin activity
FE240_18100	COG0668	transmembrane transport
FE240_18105	COG1309	transcriptional regulator
FE240_18110	COG0756	dUTP diphosphatase activity
FE240_18115	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
FE240_18120	COG2003	Belongs to the UPF0758 family
FE240_18125	COG0227	Belongs to the bacterial ribosomal protein bL28 family
FE240_18130	COG0267	Belongs to the bacterial ribosomal protein bL33 family
FE240_18140	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
FE240_18145	COG2990	Protein conserved in bacteria
FE240_18150	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
FE240_18155	COG0859	PFAM glycosyl transferase family 9
FE240_18160	COG0463	Glycosyl transferase, family 2
FE240_18165	COG0366	Alpha amylase catalytic
FE240_18175	COG3187	Heat shock protein
FE240_18180	COG0443	Heat shock 70 kDa protein
FE240_18185	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FE240_18195	COG3045	CreA protein
FE240_18215	COG0174	glutamine synthetase
FE240_18235	COG3842	ATPase activity
FE240_18240	COG1176	ABC-type spermidine putrescine transport system, permease component I
FE240_18245	COG1177	transmembrane transport
FE240_18250	COG2258	MOSC domain
FE240_18275	COG2249	NAD(P)H dehydrogenase (quinone) activity
FE240_18290	COG1770	oligopeptidase
FE240_18295	COG0251	oxidation-reduction process
FE240_18300	COG0425	Belongs to the sulfur carrier protein TusA family
FE240_18320	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
FE240_18325	COG0385	Bile acid
FE240_18335	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FE240_18340	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FE240_18375	COG1262	PFAM Formylglycine-generating sulfatase enzyme
FE240_18385	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
FE240_18390	COG0254	rRNA binding
FE240_18395	COG0702	epimerase
FE240_18400	COG0281	malic enzyme
FE240_18405	COG2205	protein histidine kinase activity
FE240_18410	COG0745	RESPONSE REGULATOR receiver
FE240_18430	COG0183	Belongs to the thiolase family
FE240_18435	COG1250	3-hydroxyacyl-CoA dehydrogenase
FE240_18435	COG1024	Enoyl-CoA hydratase
FE240_18440	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FE240_18445	COG0006	proline dipeptidase activity
FE240_18450	COG1739	Uncharacterized protein family UPF0029
FE240_18455	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
FE240_18460	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
FE240_18505	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
FE240_18510	COG1288	antiporter activity
FE240_18525	COG3706	GGDEF domain
FE240_18540	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
FE240_18545	COG0569	domain protein
FE240_18550	COG0812	UDP-N-acetylmuramate dehydrogenase activity
FE240_18560	COG2056	Na+-H+ antiporter family
FE240_18565	COG1072	(Pantothenic acid kinase))
FE240_18585	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
FE240_18600	COG0250	Participates in transcription elongation, termination and antitermination
FE240_18605	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
FE240_18610	COG0081	regulation of translation
FE240_18615	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
FE240_18620	COG0222	ribosome binding
FE240_18625	COG0085	RNA polymerase activity
FE240_18630	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
FE240_18635	COG2964	Protein conserved in bacteria
FE240_18640	COG0251	oxidation-reduction process
FE240_18650	COG2923	Belongs to the DsrF TusC family
FE240_18655	COG2168	tRNA wobble position uridine thiolation
FE240_18660	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
FE240_18665	COG0049	tRNA binding
FE240_18670	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
FE240_18675	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
FE240_18680	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
FE240_18715	COG0402	S-adenosylhomocysteine deaminase activity
FE240_18720	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
FE240_18730	COG3165	ubiquinone biosynthetic process from chorismate
FE240_18735	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
FE240_18745	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
FE240_18750	COG0805	protein transport
FE240_18755	COG0084	hydrolase, TatD family'
FE240_18765	COG1196	nuclear chromosome segregation
FE240_18805	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FE240_18815	COG0339	signal peptide processing
FE240_18825	COG0742	ribosomal rna small subunit methyltransferase
FE240_18835	COG2937	Belongs to the GPAT DAPAT family
FE240_18840	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
FE240_18855	COG0534	Mate efflux family protein
FE240_18860	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
FE240_18865	COG2205	protein histidine kinase activity
FE240_18870	COG0745	RESPONSE REGULATOR receiver
FE240_18880	COG1045	serine acetyltransferase
FE240_18890	COG3074	FtsZ-dependent cytokinesis
FE240_18895	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
FE240_18900	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FE240_18900	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FE240_18905	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily