locus-tag	class	description
E5E96_00015	ENOG4108I19	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis (By similarity)
E5E96_00020	ENOG4105C1B	dTDP-glucose 4-6-dehydratase
E5E96_00025	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
E5E96_00035	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
E5E96_00040	ENOG4108IG5	Transcriptional regulator
E5E96_00060	ENOG4105C29	acyl-CoA thioesterase
E5E96_00065	ENOG4105FE9	pseudouridine synthase
E5E96_00070	ENOG4105K8I	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves (By similarity)
E5E96_00080	ENOG4107RTD	sua5 ycio yrdc ywlc family protein
E5E96_00085	ENOG4105DB7	PHP domain protein
E5E96_00090	ENOG4105CRQ	synthase (Component I)
E5E96_00095	ENOG4108EFP	Anthranilate synthase component II
E5E96_00100	ENOG4108I0Q	anthranilate phosphoribosyltransferase
E5E96_00105	ENOG4105DK0	Indole-3-glycerol phosphate synthase
E5E96_00110	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
E5E96_00115	ENOG4105F6H	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate (By similarity)
E5E96_00140	ENOG4105S2T	inner membrane protein YbcI
E5E96_00160	ENOG4105D9N	nucleoside
E5E96_00175	ENOG4105KAF	membrAne
E5E96_00190	ENOG4107RDB	Major Facilitator
E5E96_00195	ENOG4105F1R	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group (By similarity)
E5E96_00200	ENOG41090KH	cytochrome o ubiquinol oxidase (subunit iv)
E5E96_00205	ENOG4105CCU	oxidase (Subunit III)
E5E96_00210	ENOG4105BZ9	Cytochrome C oxidase, subunit I
E5E96_00215	ENOG4105E2S	oxidase) subunit II
E5E96_00275	ENOG4105CGK	Exodeoxyribonuclease III
E5E96_00295	ENOG4105EP1	Efflux transporter rnd family, mfp subunit
E5E96_00300	ENOG4108IJF	Heavy metal efflux pump, CzcA
E5E96_00320	ENOG4107RMF	Catalyzes both the ATP-dependent activation of exogenously supplied lipoate to lipoyl-AMP and the transfer of the activated lipoyl onto the lipoyl domains of lipoate-dependent enzymes (By similarity)
E5E96_00325	ENOG4105BZU	Histidine kinase
E5E96_00350	ENOG41080HT	Transcriptional regulator, arsr family
E5E96_00370	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
E5E96_00375	ENOG4105CFG	Acts as a chaperone (By similarity)
E5E96_00380	ENOG4105K90	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
E5E96_00385	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
E5E96_00395	ENOG4105E2M	Manganese-dependent inorganic pyrophosphatase
E5E96_00405	ENOG4105DJY	efflux transporter, rnd family, mfp subunit
E5E96_00410	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
E5E96_00415	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
E5E96_00420	ENOG4105Q26	Siderophore-interacting protein
E5E96_00425	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
E5E96_00430	ENOG4108YX2	DNA-binding protein
E5E96_00445	ENOG4105KAF	membrAne
E5E96_00460	ENOG4105CJP	fad dependent oxidoreductase
E5E96_00465	ENOG4107VRI	Transcriptional regulator
E5E96_00470	ENOG4105C26	Dehydrogenase
E5E96_00475	ENOG4108JPW	Aminotransferase
E5E96_00480	ENOG4105CUB	amino acid
E5E96_00485	ENOG4105CUB	amino acid
E5E96_00500	ENOG4108V1T	peptidylprolyl cis-trans isomerase
E5E96_00505	ENOG4105C8E	extradiol ring-cleavage dioxygenase class IIi protein subunit b
E5E96_00510	ENOG4105BZU	Histidine kinase
E5E96_00525	ENOG4108QW8	Purine nucleoside phosphorylase deoD-type
E5E96_00550	ENOG4105C5H	ABC transporter
E5E96_00570	ENOG4105D98	threonine synthase
E5E96_00575	ENOG4105D5I	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate (By similarity)
E5E96_00590	ENOG4106FVC	RNA methyltransferase
E5E96_00595	ENOG4105VS7	Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue. This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon. When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation (By similarity)
E5E96_00610	ENOG4108YYX	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. Modulates RNA-binding and helicase activities of the degradosome (By similarity)
E5E96_00620	ENOG41065U4	response regulator
E5E96_00635	ENOG4108JJ9	ABC, transporter
E5E96_00640	ENOG4108JJ8	(ABC) transporter
E5E96_00660	ENOG4108R96	Methyltransferase, YaeB family
E5E96_00675	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
E5E96_00680	ENOG4105C6T	cysteine synthase
E5E96_00685	ENOG4105KZ7	phosphocarrier protein hpr
E5E96_00690	ENOG4105BZ3	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity)
E5E96_00695	ENOG4105C5Y	PTS System
E5E96_00710	ENOG4105CPW	cytochrome b561
E5E96_00720	ENOG4105EYH	Exonuclease
E5E96_00725	ENOG4105EYH	Exonuclease
E5E96_00730	ENOG4107RH8	nuclease SbcCD subunit D
E5E96_00740	ENOG4105DH7	May be involved in recombination (By similarity)
E5E96_00750	ENOG4105CKD	glutathione-regulated potassium-efflux system protein
E5E96_00765	ENOG4105CA9	Pyruvate kinase
E5E96_00770	ENOG4105EGS	Mechanosensitive ion channel
E5E96_00780	ENOG4105HHQ	6-phosphogluconolactonase (EC 3.1.1.31)
E5E96_00785	ENOG4105C2W	permease
E5E96_00790	ENOG4107R1I	NAD-dependent malic enzyme
E5E96_00795	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
E5E96_00805	ENOG4105QAX	Iron-sulfur
E5E96_00810	ENOG4108IEG	Formate dehydrogenase Alpha subunit
E5E96_00810	ENOG4108IEG	Formate dehydrogenase Alpha subunit
E5E96_00840	ENOG4105BZ4	penicillin-binding protein
E5E96_00850	ENOG4107H9G	Necessary for formate dehydrogenase activity (By similarity)
E5E96_00855	ENOG4105HD0	Transcriptional regulator of molybdate metabolism, LysR family
E5E96_00860	ENOG4105BZU	Histidine kinase
E5E96_00865	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
E5E96_00875	ENOG4107A5B	Binding-protein-dependent transport systems, inner membrane component
E5E96_00880	ENOG4108IUZ	ABC transporter
E5E96_00885	ENOG4105C6R	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor (By similarity)
E5E96_00890	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
E5E96_00895	ENOG4105DR8	Membrane
E5E96_00905	ENOG4107SDU	Methyl-accepting chemotaxis
E5E96_00935	ENOG4105XIQ	Protein of unknown function (DUF2517)
E5E96_00960	ENOG4108J59	Extracellular solute-binding protein, family 5
E5E96_00970	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
E5E96_00980	ENOG4108JQ7	(ABC) transporter
E5E96_00990	ENOG4105RD7	BadF BadG BcrA BcrD
E5E96_01000	ENOG4107RHT	methyl-accepting chemotaxis sensory transducer with Pas Pac sensor
E5E96_01015	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
E5E96_01020	ENOG4105EY2	Catalyzes the hydrolysis of N(2)-succinylarginine into N(2)-succinylornithine, ammonia and CO(2) (By similarity)
E5E96_01025	ENOG4105ERU	peptidase
E5E96_01030	ENOG4105UBK	short-chain dehydrogenase reductase
E5E96_01035	ENOG4105C5Q	Transcriptional regulator
E5E96_01045	ENOG4105C87	Aminotransferase class I and II
E5E96_01060	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
E5E96_01065	ENOG4108V1U	phospholipid-binding protein
E5E96_01075	ENOG4107WCA	isomerase
E5E96_01080	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
E5E96_01085	ENOG4105DR5	peptidase
E5E96_01090	ENOG4105ED7	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling (By similarity)
E5E96_01095	ENOG4105TMR	Functions as a holding molecular chaperone (holdase) which stabilizes unfolding intermediates and rapidly releases them in an active form once stress has abated. Plays an important role in protecting cells from severe heat shock and starvation, as well as in acid resistance of stationary-phase cells. It catalyzes the conversion of methylglyoxal (MG) to D-lactate in a single glutathione (GSH)-independent step (By similarity)
E5E96_01105	ENOG4105KME	endoribonuclease L-psp
E5E96_01115	ENOG4105CV1	Transketolase (EC 2.2.1.1)
E5E96_01120	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
E5E96_01125	ENOG4105GPY	SprT protein
E5E96_01135	ENOG4105QF0	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity)
E5E96_01140	ENOG4105D7Z	glutathione synthase
E5E96_01150	ENOG4108UJU	UPF0301 protein
E5E96_01155	ENOG4107Y66	Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity)
E5E96_01160	ENOG4105DUX	Transporter
E5E96_01165	ENOG41066YJ	Beta-lactamase
E5E96_01170	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
E5E96_01180	ENOG4105F8C	transglutaminase domain-containing protein
E5E96_01185	ENOG4105BZG	amino acid carrier protein
E5E96_01190	ENOG4105CW3	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
E5E96_01205	ENOG4105D5S	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine (By similarity)
E5E96_01210	ENOG4108VKA	Acts as a radical domain for damaged PFL and possibly other radical proteins (By similarity)
E5E96_01215	ENOG4105CK2	sodium dicarboxylate symporter
E5E96_01220	ENOG4105CXR	Phospho-2-dehydro-3-deoxyoctonate aldolase
E5E96_01225	ENOG41063JG	Transcriptional regulator
E5E96_01235	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
E5E96_01240	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
E5E96_01245	ENOG4105C7E	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) (By similarity)
E5E96_01250	ENOG4105C1U	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein (By similarity)
E5E96_01255	ENOG4105CTR	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol (By similarity)
E5E96_01265	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
E5E96_01270	ENOG4105CGH	5'-nucleotidase
E5E96_01275	ENOG4108ZPD	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity)
E5E96_01280	ENOG4105C3G	gtp-binding protein
E5E96_01325	ENOG4107QWE	)-transporter
E5E96_01330	ENOG4106Z1T	Nicotinamide Mononucleotide Transporter
E5E96_01335	ENOG4107SXA	Phosphorylase
E5E96_01355	ENOG4105QFC	Hsc56 co-chaperone of HscC
E5E96_01370	ENOG4105CG3	alpha amylase, catalytic region
E5E96_01380	ENOG4105D95	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin (By similarity)
E5E96_01390	ENOG4107VXZ	Hydrolase
E5E96_01400	ENOG4105C26	Dehydrogenase
E5E96_01410	ENOG4105C8Y	Acetylornithine aminotransferase
E5E96_01425	ENOG4105C31	Tryptophanyl-tRNA synthetase
E5E96_01435	ENOG4105DJV	ribulose-phosphate 3-epimerase
E5E96_01445	ENOG4105DFE	Dna adenine methylase
E5E96_01455	ENOG4105D49	3-dehydroquinate synthase
E5E96_01460	ENOG4105KHV	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
E5E96_01465	ENOG4105E4G	Type IV pilus
E5E96_01495	ENOG4105C5Q	Transcriptional regulator
E5E96_01500	ENOG4105C8Q	Methyl-accepting chemotaxis
E5E96_01515	ENOG4105EJC	lysr family transcriptional regulator
E5E96_01530	ENOG4105DR5	peptidase
E5E96_01545	ENOG4108QXE	glycerophosphoryl diester phosphodiesterase
E5E96_01550	ENOG4105C8Q	Methyl-accepting chemotaxis
E5E96_01560	ENOG4105E33	succinate dehydrogenase
E5E96_01565	ENOG4108WJH	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane (By similarity)
E5E96_01570	ENOG4108VP9	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane (By similarity)
E5E96_01590	ENOG4105T0Z	Conserved Protein
E5E96_01625	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
E5E96_01630	ENOG4105DHQ	Histidine kinase
E5E96_01650	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
E5E96_01660	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
E5E96_01665	ENOG4108R5S	membrane
E5E96_01675	ENOG4105C5I	Dehydrogenase
E5E96_01685	ENOG4105BZU	Histidine kinase
E5E96_01695	ENOG4105EVE	HAD-superfamily hydrolase subfamily IA variant 3
E5E96_01705	ENOG4106KR7	LysR family Transcriptional regulator
E5E96_01710	ENOG4105BZU	Histidine kinase
E5E96_01720	ENOG4106XMA	In vivo, quickly hydrolyzes the ureidoacrylate peracid to avoid toxicity, but can also hydrolyzes ureidoacrylate that is formed spontaneously from ureidoacrylate peracid. One of the products of hydrolysis, carbamate, hydrolyzes spontaneously, thereby releasing one of the pyrimidine rings nitrogen atoms as ammonia and one of its carbons as CO2 (By similarity)
E5E96_01725	ENOG4105EAK	ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family
E5E96_01730	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
E5E96_01735	ENOG4105C9A	Phoh family
E5E96_01740	ENOG4105KGE	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA (By similarity)
E5E96_01745	ENOG4108JU5	Magnesium and cobalt efflux protein
E5E96_01750	ENOG4105CE8	Transfers the fatty acyl group on membrane lipoproteins (By similarity)
E5E96_01755	ENOG4107PAI	alpha helical protein
E5E96_01760	ENOG4105C8T	Leucyl-tRNA synthetase
E5E96_01775	ENOG4108Z1W	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity)
E5E96_01780	ENOG4105KEM	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation (By similarity)
E5E96_01785	ENOG4108UXA	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA (By similarity)
E5E96_01790	ENOG4105CJN	penicillin-binding protein
E5E96_01795	ENOG4105CNI	cell division protein FtsW
E5E96_01800	ENOG4105CNI	cell division protein FtsW
E5E96_01805	ENOG4105CVE	Lytic murein transglycosylase
E5E96_01810	ENOG4105K6T	rare lipoprotein A
E5E96_01815	ENOG4105DZ1	carboxypeptidase
E5E96_01820	ENOG4108Z43	UPF0250 protein
E5E96_01825	ENOG4108BDP	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity)
E5E96_01835	ENOG4105C0G	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity)
E5E96_01845	ENOG4105MJ9	esterase
E5E96_01850	ENOG4108IUB	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
E5E96_01865	ENOG4107SWG	transcriptional regulator MERR family
E5E96_01870	ENOG4105C2R	Single-stranded-DNA-specific exonuclease (RecJ)
E5E96_01875	ENOG4105T95	Thiol disulfide interChange protein
E5E96_01880	ENOG4105M2E	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell (By similarity)
E5E96_01885	ENOG4105BZU	Histidine kinase
E5E96_01890	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
E5E96_01895	ENOG41071R3	Low-potential electron donor to a number of redox enzymes (By similarity)
E5E96_01915	ENOG4107N1Q	ErfK YbiS YcfS YnhG family protein
E5E96_01945	ENOG4105DB1	molybdopterin oxidoreductase
E5E96_01950	ENOG4106WHD	Tetrathionate reductase
E5E96_01955	ENOG4105QA4	4Fe-4S Ferredoxin, iron-sulfur binding domain protein
E5E96_01960	ENOG4105BZU	Histidine kinase
E5E96_01965	ENOG4108ZXC	Two component transcriptional regulator, luxr family
E5E96_01970	ENOG4108HRK	Histidine kinase
E5E96_01975	ENOG4108NEV	two component transcriptional regulator, LytTR family
E5E96_01985	ENOG4105EQ6	Hydrolyzes dipeptides containing N-terminal aspartate residues. May play a role in allowing the cell to use peptide aspartate to spare carbon otherwise required for the synthesis of the aspartate family of amino acids (By similarity)
E5E96_02000	ENOG41090EX	DsrE family
E5E96_02005	ENOG4105BZU	Histidine kinase
E5E96_02010	ENOG4105E5W	Transporter
E5E96_02015	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
E5E96_02020	ENOG4105K77	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity)
E5E96_02025	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
E5E96_02030	ENOG4105KG7	Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity)
E5E96_02035	ENOG4107QHU	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
E5E96_02040	ENOG4105CHV	Transcription elongation factor NusA
E5E96_02045	ENOG4105K7D	Required for maturation of 30S ribosomal subunits (By similarity)
E5E96_02060	ENOG4105NTZ	Preprotein translocase subunit SecG
E5E96_02065	ENOG4105CP7	Triose-phosphate isomerase
E5E96_02070	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
E5E96_02075	ENOG4105EEI	dihydropteroate synthase
E5E96_02080	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
E5E96_02085	ENOG4105F7M	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit (By similarity)
E5E96_02090	ENOG4105HBR	Rna-binding protein
E5E96_02100	ENOG4108UKH	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
E5E96_02105	ENOG4107XSU	flagellar motor protein motb
E5E96_02110	ENOG4105E14	MotA TolQ exbB proton channel
E5E96_02115	ENOG41067QG	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
E5E96_02120	ENOG4105CTB	Polyprenyl synthetase
E5E96_02125	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
E5E96_02135	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
E5E96_02145	ENOG4108JQ6	ABC transporter
E5E96_02150	ENOG4108ZAI	phosphatidylglycerophosphatase a
E5E96_02155	ENOG4105CG2	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity)
E5E96_02160	ENOG4107YIM	Involved in the transcription termination process (By similarity)
E5E96_02165	ENOG4108UTT	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity)
E5E96_02185	ENOG4105D1W	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity)
E5E96_02190	ENOG4108Z11	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes (By similarity)
E5E96_02200	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
E5E96_02210	ENOG4109039	Involved in the biogenesis of TorA. Acts on TorA before the insertion of the molybdenum cofactor and, as a result, probably favors a conformation of the apoenzyme that is competent for acquiring the cofactor (By similarity)
E5E96_02230	ENOG4105BZU	Histidine kinase
E5E96_02240	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
E5E96_02245	ENOG4108Z38	Catalyzes a trans-dehydration via an enolate intermediate (By similarity)
E5E96_02250	ENOG4105KM4	Acetyl-CoA carboxylase, biotin carboxyl carrier protein
E5E96_02255	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
E5E96_02265	ENOG4108IA2	Sodium pantothenate symporter
E5E96_02270	ENOG4105CI1	PTS System
E5E96_02275	ENOG4105HEI	LysR family (Transcriptional regulator
E5E96_02280	ENOG4105CIS	alcohol dehydrogenase
E5E96_02285	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
E5E96_02300	ENOG41069NU	Nitroreductase
E5E96_02310	ENOG4105D07	Signal peptide peptidase, SppA
E5E96_02330	ENOG4105VUT	cytoplasmic protein
E5E96_02335	ENOG4105HDK	L-asparaginase
E5E96_02340	ENOG4105D6U	Sodium Glutamate Symporter
E5E96_02345	ENOG4105C8Q	Methyl-accepting chemotaxis
E5E96_02355	ENOG4105CRK	lysyL-tRNA synthetase
E5E96_02360	ENOG4107TIF	Phenazine biosynthesis protein, PhzF family
E5E96_02365	ENOG4107EER	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity)
E5E96_02370	ENOG4105ET1	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate (By similarity)
E5E96_02375	ENOG4105ET3	Reduction of activated sulfate into sulfite (By similarity)
E5E96_02380	ENOG4105GIJ	Glycine betaine
E5E96_02385	ENOG4108HQS	Glycine betaine
E5E96_02390	ENOG4108IJ7	Glycine betaine
E5E96_02400	ENOG4107XM3	UPF0442 protein
E5E96_02405	ENOG4105DWK	Membrane
E5E96_02415	ENOG4108RIR	Molybdenum cofactor biosynthesis protein
E5E96_02425	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
E5E96_02430	ENOG4105C2D	reductase
E5E96_02440	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
E5E96_02475	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
E5E96_02530	ENOG4105CA0	peroxidase
E5E96_02540	ENOG4105D53	Catalyzes the hydrolysis of pseudouridine 5'-phosphate (PsiMP) to ribose 5-phosphate and uracil (By similarity)
E5E96_02545	ENOG4105DD7	kinase (PfkB family
E5E96_02580	ENOG4105C2S	Catalyzes the NADPH dependent reduction of L-gamma- glutamyl 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate (By similarity)
E5E96_02590	ENOG4108UVK	Binds to the sigma-S subunit of RNA polymerase, activating expression of sigma-S-regulated genes. Stimulates RNA polymerase holoenzyme formation and may bind to several other sigma factors, such as sigma-70 and sigma-32 (By similarity)
E5E96_02595	ENOG4105V1F	Fermentation respiration switch protein
E5E96_02600	ENOG4105DYA	Acts on guanine, xanthine and to a lesser extent hypoxanthine (By similarity)
E5E96_02610	ENOG4105CIN	aminoacyl-histidine dipeptidase
E5E96_02620	ENOG4108JQ7	(ABC) transporter
E5E96_02635	ENOG4108IYQ	Binding-protein-dependent transport systems inner membrane component
E5E96_02640	ENOG4108I5X	binding-protein-dependent transport systems inner membrane Component
E5E96_02645	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
E5E96_02665	ENOG4109015	Biopolymer transport protein exbD tolR
E5E96_02715	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
E5E96_02720	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
E5E96_02725	ENOG4105C8Q	Methyl-accepting chemotaxis
E5E96_02735	ENOG4105VEQ	Cold shock protein
E5E96_02775	ENOG4108RBP	3'-to-5' exoribonuclease specific for small oligoribonucleotides (By similarity)
E5E96_02780	ENOG4105E06	May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity)
E5E96_02785	ENOG4105DJ4	phosphatidylserine decarboxylase
E5E96_02790	ENOG4105VYA	Uncharacterized conserved protein (DUF2132)
E5E96_02805	ENOG4108KBJ	Inner membrane protein YkgB
E5E96_02825	ENOG4105BZU	Histidine kinase
E5E96_02830	ENOG4105KQT	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome (By similarity)
E5E96_02865	ENOG4105BZ1	(ABC) transporter
E5E96_02870	ENOG4105SUV	lipoprotein YgdR
E5E96_02875	ENOG4105RX7	peptidase S8 and S53, subtilisin, kexin, sedolisin
E5E96_02880	ENOG4107RM6	sulfurtransferase
E5E96_02885	ENOG4105CSV	Glutaminase
E5E96_02890	ENOG41090ED	Protein with unknown function (DUF469)
E5E96_02895	ENOG4105CZ1	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity)
E5E96_02900	ENOG4105IIU	Aminopeptidase
E5E96_02905	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
E5E96_02910	ENOG4105BZU	Histidine kinase
E5E96_02915	ENOG4105ECP	epimerase
E5E96_02920	ENOG4105CV6	ABC transporter, permease
E5E96_02925	ENOG4108I0Y	(ABC) transporter
E5E96_02930	ENOG4108UJV	acyl-CoA thioesterase i
E5E96_02945	ENOG4105D0C	transport protein
E5E96_02950	ENOG4108UT2	hemolysin iii
E5E96_02955	ENOG4105DY8	decarboxylase
E5E96_02960	ENOG4107835	probably involved in intracellular septation (By similarity)
E5E96_02965	ENOG4105K9H	YciI-like protein
E5E96_02970	ENOG4108RNI	3'(2')5'-bisphosphate nucleotidase
E5E96_02975	ENOG41083P1	competence protein ComEA helix-hairpin-helix repeat protein
E5E96_02980	ENOG4105C3Y	UTP-glucose-1-phosphate uridylyltransferase
E5E96_02985	ENOG4105DUX	Transporter
E5E96_02990	ENOG4105I93	response regulator
E5E96_03025	ENOG4107V40	secretion protein, HlyD family
E5E96_03035	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
E5E96_03040	ENOG4105VY0	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters (By similarity)
E5E96_03045	ENOG4108NIW	Leucine export protein LeuE
E5E96_03070	ENOG4108YX9	iron--sulfur cluster insertion protein erpA
E5E96_03080	ENOG4105CMQ	Chloride channel
E5E96_03085	ENOG4105CDM	Glutamate-1-semialdehyde aminotransferase
E5E96_03100	ENOG41076MN	Phosphoesterase, PA-phosphatase related
E5E96_03110	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
E5E96_03120	ENOG41090TI	Catalyzes the excretion of spermidine (By similarity)
E5E96_03125	ENOG4108ZBZ	Catalyzes the excretion of spermidine (By similarity)
E5E96_03130	ENOG4108YZK	glyoxalase bleomycin resistance protein dioxygenase
E5E96_03135	ENOG4105BZ4	penicillin-binding protein
E5E96_03140	ENOG4105CQ7	ATP-dependent helicase
E5E96_03150	ENOG4105PW4	Sugar fermentation stimulation protein homolog
E5E96_03160	ENOG4106F3G	Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon (By similarity)
E5E96_03165	ENOG4105DJ0	Poly(A) Polymerase
E5E96_03170	ENOG4105K8U	2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
E5E96_03175	ENOG4105CCG	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is tranferred onto alpha-ketoisovalerate to form ketopantoate (By similarity)
E5E96_03180	ENOG4108IAA	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate (By similarity)
E5E96_03200	ENOG4105CIZ	coA-substrate-specific enzyme activase
E5E96_03205	ENOG4105DCU	2-hydroxyglutaryl-CoA dehydratase
E5E96_03210	ENOG4105E3A	(ABC) transporter
E5E96_03215	ENOG4105DA5	(ABC) transporter
E5E96_03220	ENOG4108UGV	hypoxanthine phosphoribosyltransferase
E5E96_03225	ENOG410630P	Transcriptional regulator
E5E96_03230	ENOG4108UMA	3-octaprenyl-4-hydroxybenzoate carboxy-lyase
E5E96_03235	ENOG4105DFU	Cell wall formation (By similarity)
E5E96_03240	ENOG4105F0N	pyrophosphate phospho-hydrolase
E5E96_03260	ENOG4108UUE	Transcriptional regulator
E5E96_03275	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
E5E96_03295	ENOG4107RHT	methyl-accepting chemotaxis sensory transducer with Pas Pac sensor
E5E96_03320	ENOG4108I67	Catalyzes the synthesis of activated sulfate (By similarity)
E5E96_03330	ENOG4105C3T	may be the GTPase, regulating ATP sulfurylase activity (By similarity)
E5E96_03335	ENOG4105C11	sulfate adenylyltransferase), subunit 2
E5E96_03340	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
E5E96_03345	ENOG4107QX8	SPFH domain, Band 7 family protein
E5E96_03350	ENOG4105G5H	Membrane
E5E96_03355	ENOG4105C2X	Arabinose 5-phosphate isomerase
E5E96_03360	ENOG4105C5H	ABC transporter
E5E96_03370	ENOG4105D6S	protein involved in catabolism of external DNA
E5E96_03375	ENOG4105EQ2	LysR family Transcriptional regulator
E5E96_03410	ENOG4108Z6Z	Transcriptional regulator
E5E96_03415	ENOG4105CK7	Sodium proline symporter
E5E96_03420	ENOG4107N1Q	ErfK YbiS YcfS YnhG family protein
E5E96_03425	ENOG4105CUY	Mechanosensitive ion channel
E5E96_03435	ENOG4105XEP	YhcH YjgK YiaL family protein
E5E96_03445	ENOG4105E3B	Multicopper oxidase
E5E96_03460	ENOG4107SQD	Transcriptional regulator, GntR family
E5E96_03485	ENOG4105C8J	)-transporter
E5E96_03495	ENOG4105C8J	)-transporter
E5E96_03510	ENOG4108K4B	hydrolase
E5E96_03525	ENOG4105EW9	transcriptional regulator AsnC family
E5E96_03540	ENOG4105K56	Transcriptional regulator
E5E96_03545	ENOG4108ZHJ	Organic hydroperoxide resistance protein
E5E96_03550	ENOG4105CJH	Alcohol dehydrogenase zinc-binding domain protein
E5E96_03555	ENOG4105EJF	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity)
E5E96_03565	ENOG4105E0X	reductase
E5E96_03575	ENOG4105C9C	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity)
E5E96_03580	ENOG4107RTM	4-alpha-glucanotransferase (EC 2.4.1.25)
E5E96_03590	ENOG4105DSB	aldose 1-epimerase
E5E96_03595	ENOG4105D0I	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate (By similarity)
E5E96_03600	ENOG4105C8Q	Methyl-accepting chemotaxis
E5E96_03675	ENOG4105UFD	tol-pal system protein YbgF
E5E96_03680	ENOG4105KCK	Peptidoglycan-associated lipoprotein
E5E96_03685	ENOG4107R6Y	Involved in the TonB-independent uptake of proteins (By similarity)
E5E96_03695	ENOG4105M8F	Biopolymer transport protein exbD tolR
E5E96_03700	ENOG4105E02	MotA TolQ exbB proton channel
E5E96_03705	ENOG4107YD3	Thioesterase
E5E96_03710	ENOG4105KJB	cyd operon protein YbgE
E5E96_03720	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
E5E96_03725	ENOG4105C4M	(Ubiquinol oxidase) subunit I
E5E96_03730	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
E5E96_03735	ENOG4105KA4	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity)
E5E96_03740	ENOG4105C8Q	Methyl-accepting chemotaxis
E5E96_03745	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
E5E96_03750	ENOG4108RZ4	Short-chain dehydrogenase reductase Sdr
E5E96_03765	ENOG4105E39	Enoyl-CoA hydratase
E5E96_03770	ENOG4106WH9	Protein of unknown function (DUF2753)
E5E96_03775	ENOG4105EQK	-acetyltransferase
E5E96_03785	ENOG4107QSI	ABC, transporter
E5E96_03800	ENOG4105VZ9	UPF0235 protein
E5E96_03805	ENOG4108VIA	integral membrane protein
E5E96_03810	ENOG4105II7	pyrroline-5-carboxylate reductase
E5E96_03815	ENOG4105DFA	alanine racemase domain protein
E5E96_03820	ENOG4105CZX	twitching motility protein
E5E96_03825	ENOG4105CZX	twitching motility protein
E5E96_03830	ENOG4105D1Q	UPF0246 protein
E5E96_03835	ENOG4105C1J	atp-dependent rna helicase
E5E96_03840	ENOG4107S47	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC) (By similarity)
E5E96_03845	ENOG4105CWM	branched-chain amino acid transport system II carrier protein
E5E96_03850	ENOG4105CWM	branched-chain amino acid transport system II carrier protein
E5E96_03865	ENOG4105MYN	Zinc uptake regulation protein
E5E96_03870	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
E5E96_03885	ENOG4105K70	DNA-binding protein
E5E96_03895	ENOG4108ZVW	Anti-RNA polymerase sigma 70 factor
E5E96_03905	ENOG4105DNJ	May play a role in the repair of endogenous alkylation damage (By similarity)
E5E96_03920	ENOG4105EAC	phosphoserine phosphatase
E5E96_03930	ENOG4105BZU	Histidine kinase
E5E96_03935	ENOG4105D3A	purine nucleoside phosphorylase DeoD-type
E5E96_03940	ENOG4105CZG	Phosphotransfer between the C1 and C5 carbon atoms of pentose (By similarity)
E5E96_03945	ENOG4105CMW	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis (By similarity)
E5E96_03950	ENOG4105FCI	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate (By similarity)
E5E96_03960	ENOG4105D9N	nucleoside
E5E96_03965	ENOG4105EYA	deoxyribonuclease
E5E96_03980	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
E5E96_03985	ENOG4105BZU	Histidine kinase
E5E96_04000	ENOG4108K5H	permease YjgP YjgQ family protein
E5E96_04005	ENOG4108M8S	permease YjgP YjgQ family protein
E5E96_04010	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
E5E96_04015	ENOG4105MYG	DNA polymerase iii, chi subunit
E5E96_04020	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
E5E96_04030	ENOG4106W5V	Membrane
E5E96_04035	ENOG41061WM	D-Alanyl-D-Alanine
E5E96_04070	ENOG4105VM8	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding (By similarity)
E5E96_04075	ENOG4105CFH	Aspartokinase
E5E96_04080	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
E5E96_04090	ENOG4105C68	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity)
E5E96_04095	ENOG4107TH8	cina domain protein
E5E96_04100	ENOG4105D86	that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity)
E5E96_04120	ENOG4105R2J	Conserved Protein
E5E96_04130	ENOG4105DR5	peptidase
E5E96_04150	ENOG4105NXV	High-affinity zinc uptake system protein
E5E96_04155	ENOG4105FDK	ABC transporter
E5E96_04160	ENOG4105FAV	ABC, transporter
E5E96_04165	ENOG4105ETT	transcriptional Regulator, LysR family
E5E96_04175	ENOG4108RG0	uracil-dna glycosylase
E5E96_04180	ENOG4105FR1	rard protein
E5E96_04190	ENOG41082IR	Excinuclease ABC C subunit domain protein
E5E96_04205	ENOG41087YS	Phage shock protein A
E5E96_04210	ENOG4107S7E	1-acyl-sn-glycerol-3-phosphate acyltransferase
E5E96_04230	ENOG4105N2G	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
E5E96_04235	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
E5E96_04280	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
E5E96_04285	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
E5E96_04290	ENOG4105DSW	Fusaric acid resistance protein
E5E96_04295	ENOG4105Y49	secretion protein, HlyD family
E5E96_04315	ENOG4105IPS	esterase
E5E96_04320	ENOG41070EG	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes (By similarity)
E5E96_04325	ENOG4108SX3	cytoplasmic protein
E5E96_04330	ENOG41087AY	ADP-Ribose pyrophosphatase
E5E96_04335	ENOG4105DFG	type I secretion outer membrane protein
E5E96_04340	ENOG4105DW0	Catalyzes the ADP transfer to D-glycero-D-manno-heptose 1-phosphate, yielding ADP-D,D-heptose (By similarity)
E5E96_04345	ENOG4105D1S	lipid A biosynthesis
E5E96_04360	ENOG4107IX6	phosphate transport regulator
E5E96_04365	ENOG4105CJ3	phosphate transporter
E5E96_04370	ENOG4108Z66	YbaK ebsC protein
E5E96_04375	ENOG41072TH	Protein of unknown function (DUF1479)
E5E96_04400	ENOG4105CMU	LysR family (Transcriptional regulator
E5E96_04410	ENOG41067MG	lrgb family
E5E96_04425	ENOG4105D4J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
E5E96_04440	ENOG4105CEN	a g-specific adenine glycosylase
E5E96_04445	ENOG4105KMG	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes (By similarity)
E5E96_04455	ENOG4105H4F	exported protein
E5E96_04470	ENOG4105UYK	outer membrane protein a
E5E96_04475	ENOG4108Q2G	(LipO)protein
E5E96_04480	ENOG4105DY2	Paraquat-inducible protein b
E5E96_04485	ENOG4105F1S	paraquat-inducible protein a
E5E96_04490	ENOG4105KW8	RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity)
E5E96_04495	ENOG4107VXZ	Hydrolase
E5E96_04510	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
E5E96_04515	ENOG4105D8J	Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle (By similarity)
E5E96_04520	ENOG4107QQ4	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans (By similarity)
E5E96_04525	ENOG4105CXW	Synthesizes alpha-1,4-glucan chains using ADP-glucose (By similarity)
E5E96_04565	ENOG4105DFD	Na H antiporter
E5E96_04570	ENOG4108M0I	Transcriptional regulator
E5E96_04575	ENOG4107TYH	extracellular solute-binding protein family 1
E5E96_04580	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
E5E96_04585	ENOG4105D81	ABC transporter, permease
E5E96_04590	ENOG4105NRK	Binding-protein-dependent transport systems, inner membrane component
E5E96_04595	ENOG4105C26	Dehydrogenase
E5E96_04605	ENOG4107AQZ	Membrane
E5E96_04615	ENOG4108UW5	maltose o-acetyltransferase
E5E96_04620	ENOG4105CG3	alpha amylase, catalytic region
E5E96_04625	ENOG4105C5Y	PTS System
E5E96_04630	ENOG4105D4X	repressor
E5E96_04660	ENOG4108Z5K	methylglyoxal synthase
E5E96_04670	ENOG4108UQY	Iron-storage protein
E5E96_04685	ENOG4105E0I	Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of tRNA(Met), by using acetyl-CoA as an acetyl donor and ATP (or GTP) (By similarity)
E5E96_04690	ENOG410904N	short-chain dehydrogenase reductase
E5E96_04695	ENOG4107R88	Chemotaxis protein (CheV)
E5E96_04700	ENOG4105DWD	nucleoside recognition domain protein
E5E96_04740	ENOG4105K7Z	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP (By similarity)
E5E96_04745	ENOG4107ZVW	dihydroneopterin aldolase
E5E96_04750	ENOG4105K8U	2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
E5E96_04760	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
E5E96_04765	ENOG4105CKI	cobalamin synthesis protein
E5E96_04775	ENOG4105E82	cytochrome subunit of dehydrogenase
E5E96_04785	ENOG4105BZU	Histidine kinase
E5E96_04790	ENOG4107QIJ	Aconitate hydratase 2
E5E96_04795	ENOG4105D78	K07001 NTE family protein
E5E96_04800	ENOG4108N3W	hemolysin secretion protein
E5E96_04805	ENOG4108N3W	hemolysin secretion protein
E5E96_04815	ENOG4107QN2	dihydrolipoyl dehydrogenase
E5E96_04820	ENOG4107QSN	dihydrolipoamide acetyltransferase
E5E96_04825	ENOG4105DAQ	Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) (By similarity)
E5E96_04830	ENOG41073TP	transcriptional regulator
E5E96_04845	ENOG4105D18	nicotinate-nucleotide pyrophosphorylase
E5E96_04860	ENOG4107QHF	type ii secretion system protein e
E5E96_04865	ENOG4105D7Q	type ii secretion system
E5E96_04880	ENOG4105DHA	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity (By similarity)
E5E96_04885	ENOG41067SF	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase (By similarity)
E5E96_04890	ENOG4105EJF	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity)
E5E96_04900	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
E5E96_04910	ENOG4105C7C	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
E5E96_04915	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
E5E96_04920	ENOG4105CIT	This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity)
E5E96_04925	ENOG4105K7E	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly (By similarity)
E5E96_04930	ENOG4105DFU	Cell wall formation (By similarity)
E5E96_04935	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
E5E96_04940	ENOG4105CNI	cell division protein FtsW
E5E96_04945	ENOG4105DMZ	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity)
E5E96_04950	ENOG4105CPY	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity)
E5E96_04955	ENOG4108EQQ	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein (By similarity)
E5E96_04960	ENOG4107EEN	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity)
E5E96_04965	ENOG4105CJN	penicillin-binding protein
E5E96_04970	ENOG41063Y6	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity)
E5E96_04975	ENOG4105CGJ	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity)
E5E96_04980	ENOG4108V6E	Cell division protein mraZ
E5E96_04990	ENOG4105E9H	Lytic Murein transglycosylase
E5E96_05000	ENOG4105ER2	Ompa motb domain protein
E5E96_05005	ENOG4107RD7	Flagellar Motor Protein, MotA
E5E96_05030	ENOG4105MQ3	flagellar protein FliS
E5E96_05035	ENOG410804A	Flagellar hook-associated 2 domain-containing protein
E5E96_05040	ENOG4105I03	Flagellin
E5E96_05045	ENOG4105I03	Flagellin
E5E96_05055	ENOG4108C80	FliB family
E5E96_05065	ENOG4105DTJ	flagellar hook-associated protein
E5E96_05070	ENOG4105E1Q	flagellar hook-associated protein
E5E96_05080	ENOG4105D92	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity)
E5E96_05085	ENOG4107W7W	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity)
E5E96_05090	ENOG4105CGA	flagellar basal-body rod protein FlgG
E5E96_05095	ENOG4108KPB	Flagellar basal-body rod protein FlgF
E5E96_05100	ENOG4105BZE	flagellar hook protein, FlgE
E5E96_05105	ENOG4105W00	Flagellar hook capping protein
E5E96_05110	ENOG4108ZC9	flagellar basal-body rod protein flgc
E5E96_05115	ENOG4105K88	Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body (By similarity)
E5E96_05140	ENOG4108JIR	Flagellum-specific ATP synthase
E5E96_05150	ENOG4105CS3	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
E5E96_05155	ENOG4105C1F	The M ring may be actively involved in energy transduction (By similarity)
E5E96_05160	ENOG4105VQ0	flagellar hook-basal body complex protein fliE
E5E96_05175	ENOG4105D00	flagellar biosynthetic protein flhB
E5E96_05180	ENOG4105D19	Role in flagellar biosynthesis (By similarity)
E5E96_05185	ENOG4105VS8	Flagellar biosynthetic protein fliq
E5E96_05190	ENOG4105CN7	Flagellar biosynthetic protein FliP
E5E96_05195	ENOG4105DD5	Flagellar motor switch protein
E5E96_05210	ENOG4105CU0	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity)
E5E96_05215	ENOG4105E1C	Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1A (PBP1a) (By similarity)
E5E96_05220	ENOG41082RQ	UPF0102 protein
E5E96_05225	ENOG4105F55	Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate (By similarity)
E5E96_05230	ENOG4105W4M	Transport-associated protein
E5E96_05235	ENOG4105KB2	stringent starvation protein b
E5E96_05240	ENOG4107MKT	Stringent starvation protein a
E5E96_05245	ENOG4105EIX	cytochrome c1
E5E96_05250	ENOG4105DJ5	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
E5E96_05255	ENOG4108R5F	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
E5E96_05260	ENOG4108UJD	30S ribosomal protein S9
E5E96_05265	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
E5E96_05270	ENOG4105D6Z	AFG1 family ATPase
E5E96_05280	ENOG4105C0H	protease
E5E96_05285	ENOG4105C0H	protease
E5E96_05315	ENOG41069H0	dihydroorotase EC 3.5.2.3
E5E96_05330	ENOG4105EMD	TRANSCRIPTIONal
E5E96_05335	ENOG41080Z8	PHOSPHOCARRIER protein
E5E96_05340	ENOG4105C21	Displays ATPase and GTPase activities (By similarity)
E5E96_05345	ENOG4107RM2	PTS IIA-like nitrogen-regulatory protein PtsN
E5E96_05350	ENOG41080QH	sigma 54 modulation protein ribosomal protein S30EA
E5E96_05355	ENOG4105DTW	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
E5E96_05360	ENOG4108IUZ	ABC transporter
E5E96_05365	ENOG4105WI0	lipopolysaccharide transport periplasmic protein lptA
E5E96_05370	ENOG4108P1K	Required for the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane (By similarity)
E5E96_05380	ENOG4105C2X	Arabinose 5-phosphate isomerase
E5E96_05385	ENOG4105DHJ	ABC, transporter
E5E96_05390	ENOG4105CY3	ABC transporter, permease
E5E96_05395	ENOG4107PE3	Mammalian cell entry related domain protein
E5E96_05400	ENOG4105E3I	toluene tolerance
E5E96_05410	ENOG4105VFK	BolA family
E5E96_05415	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
E5E96_05420	ENOG4105CMS	peptidase U62, modulator of DNA gyrase
E5E96_05425	ENOG4105N42	UPF0307 protein
E5E96_05435	ENOG41090HJ	UPF0265 protein
E5E96_05465	ENOG4108JCI	Transcriptional regulator
E5E96_05470	ENOG4105DKK	Benzoate
E5E96_05480	ENOG4105SYT	Methylenetetrahydrofolate reductase
E5E96_05495	ENOG4105C8Q	Methyl-accepting chemotaxis
E5E96_05500	ENOG4105EIF	outer membrane protein W
E5E96_05505	ENOG4105BZU	Histidine kinase
E5E96_05510	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
E5E96_05515	ENOG41086KC	Transcriptional regulator
E5E96_05520	ENOG4108UUM	single-stranded DNA-binding protein
E5E96_05565	ENOG4108Z3N	Transcriptional regulator
E5E96_05595	ENOG4105VEQ	Cold shock protein
E5E96_05600	ENOG4105D05	Receptor
E5E96_05610	ENOG4105E0F	Histidine kinase
E5E96_05650	ENOG4105KHA	Glyoxalase Bleomycin resistance protein (Dioxygenase
E5E96_05665	ENOG4107QYX	exodeoxyribonuclease v alpha
E5E96_05670	ENOG4107QKA	exodeoxyribonuclease V beta
E5E96_05675	ENOG4105DSY	exodeoxyribonuclease V, gamma
E5E96_05680	ENOG4108VBZ	doxx family
E5E96_05685	ENOG4105C2I	pirin domain protein
E5E96_05695	ENOG4105CWB	LysR family transcriptional Regulator
E5E96_05720	ENOG4105E4X	binding-protein-dependent transport systems inner membrane Component
E5E96_05730	ENOG4108IJ6	ABC transporter
E5E96_05740	ENOG4105BZU	Histidine kinase
E5E96_05760	ENOG4105WCN	acetyltransferase
E5E96_05765	ENOG4105CH6	catalase
E5E96_05795	ENOG4105IPI	Membrane
E5E96_05800	ENOG4105EMU	Dehydrogenase
E5E96_05805	ENOG4105DWY	Agmatine deiminase
E5E96_05810	ENOG4105ETT	transcriptional Regulator, LysR family
E5E96_05815	ENOG4108JU9	GAF modulated sigma54 specific transcriptional regulator Fis family
E5E96_05830	ENOG4108UTZ	Dihydroxyacetone kinase
E5E96_05835	ENOG4105CMT	Dihydroxyacetone kinase
E5E96_05840	ENOG4105C7N	Xanthine uracil vitamin C permease
E5E96_05880	ENOG4108ZI0	d,d-heptose 1,7-bisphosphate phosphatase
E5E96_05885	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
E5E96_05890	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
E5E96_05895	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
E5E96_05900	ENOG4108UKE	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity)
E5E96_05905	ENOG4105YKK	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions (By similarity)
E5E96_05910	ENOG4108ZKU	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions (By similarity)
E5E96_05920	ENOG4105KME	endoribonuclease L-psp
E5E96_05925	ENOG4105WWK	YheO domain protein
E5E96_05930	ENOG4105D27	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
E5E96_05935	ENOG4108IIJ	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
E5E96_05940	ENOG4105KBC	Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity)
E5E96_05945	ENOG4108VZM	50s ribosomal protein L10
E5E96_05950	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
E5E96_05955	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
E5E96_05960	ENOG4105E5V	Participates in transcription elongation, termination and antitermination (By similarity)
E5E96_05965	ENOG4105PM1	preprotein translocase subunit SecE
E5E96_05975	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
E5E96_05990	ENOG4105CS9	pantothenic acid kinase
E5E96_05995	ENOG4105HJX	Biotin- acetyl-CoA-carboxylase ligase
E5E96_06000	ENOG4105D4A	Cell wall formation (By similarity)
E5E96_06005	ENOG4107ZYR	domain protein
E5E96_06015	ENOG4105E7U	AraC family transcriptional regulator
E5E96_06030	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
E5E96_06035	ENOG4105CUW	cytochrome C-TYPE protein
E5E96_06040	ENOG4107QY8	reductase
E5E96_06050	ENOG4105IFJ	Histidine kinase
E5E96_06055	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
E5E96_06070	ENOG4105DQ2	Is probably involved in the electron transfer between its heme and the molybdenum cofactor of the reductase catalytic subunit YedY (By similarity)
E5E96_06085	ENOG4108UQ5	membrane protein YcdZ
E5E96_06090	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
E5E96_06100	ENOG4107WP9	Histidine kinase
E5E96_06115	ENOG410642E	Short chain dehydrogenase
E5E96_06120	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
E5E96_06135	ENOG4108VVK	transcriptional Regulator, AsnC
E5E96_06140	ENOG4105CU9	asparagine synthetase A
E5E96_06150	ENOG4107T8T	UPF0173 metal-dependent hydrolase
E5E96_06155	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
E5E96_06160	ENOG4105DBW	Multi-copper polyphenol oxidoreductase laccase
E5E96_06165	ENOG4105C34	Pseudouridine synthase
E5E96_06170	ENOG4106SNF	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
E5E96_06175	ENOG4107QMW	pyridine nucleotide-disulfide oxidoreductase
E5E96_06185	ENOG4105CEM	UPF0597 protein
E5E96_06195	ENOG4105C15	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
E5E96_06200	ENOG4108IIE	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
E5E96_06205	ENOG4108I6A	alcohol dehydrogenase
E5E96_06210	ENOG4105CF7	AraC family transcriptional regulator
E5E96_06215	ENOG4105QNF	Outer membrane lipoprotein
E5E96_06220	ENOG4105C8Q	Methyl-accepting chemotaxis
E5E96_06225	ENOG4105DJ4	phosphatidylserine decarboxylase
E5E96_06245	ENOG4105CXT	aspartate transcarbamylase
E5E96_06250	ENOG4108R9M	Involved in allosteric regulation of aspartate carbamoyltransferase (By similarity)
E5E96_06255	ENOG410682Y	Regulates arginine biosynthesis genes (By similarity)
E5E96_06260	ENOG4105CSX	c4-dicarboxylate anaerobic carrier
E5E96_06265	ENOG4105DBV	ornithine carbamoyltransferase
E5E96_06270	ENOG4105C5B	carbamate kinase
E5E96_06295	ENOG4105C8Q	Methyl-accepting chemotaxis
E5E96_06300	ENOG4107SDZ	Galactoside transport system permease protein mglC
E5E96_06305	ENOG4105C2J	ABC transporter
E5E96_06315	ENOG4105CNT	hydrolase family 2
E5E96_06320	ENOG41060NJ	transcriptional regulator
E5E96_06325	ENOG4105CMR	udp-glucose 4-epimerase
E5E96_06330	ENOG4105F0Z	galactose-1-phosphate uridylyltransferase
E5E96_06335	ENOG4105CRD	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P) (By similarity)
E5E96_06340	ENOG4105ENN	converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose (By similarity)
E5E96_06345	ENOG4105CPC	Aldo Keto reductase
E5E96_06350	ENOG4105DWR	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity)
E5E96_06355	ENOG4108NIX	Factor ChrR
E5E96_06360	ENOG4105K6V	RNA polymerase
E5E96_06370	ENOG4105C75	arginyL-tRNA synthetase
E5E96_06380	ENOG4108R5P	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery (By similarity)
E5E96_06385	ENOG4105C4N	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis (By similarity)
E5E96_06390	ENOG4105C57	major facilitator superfamily
E5E96_06400	ENOG4107QZF	nitrite reductase NADPH large subunit
E5E96_06405	ENOG4105WZK	nitrite reductase NADPH small subunit
E5E96_06410	ENOG4107V9H	nitrite transporter
E5E96_06415	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
E5E96_06420	ENOG4105CJW	magnesium transporter
E5E96_06425	ENOG4108NVR	Methyl-accepting chemotaxis
E5E96_06430	ENOG4108YYX	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. Modulates RNA-binding and helicase activities of the degradosome (By similarity)
E5E96_06435	ENOG4105EX9	Membrane
E5E96_06445	ENOG4105CNG	UPF0061 protein
E5E96_06450	ENOG4105N7H	Cytochrome
E5E96_06455	ENOG4105C9U	ATP-dependent DNA helicase RecQ
E5E96_06460	ENOG4108VUY	thioesterase Superfamily protein
E5E96_06475	ENOG4108RPX	mosc domain containing protein
E5E96_06480	ENOG4105D38	putrescine abc transporter
E5E96_06485	ENOG4105F38	ABC transporter, permease
E5E96_06490	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
E5E96_06495	ENOG4108HM4	ABC transporter
E5E96_06505	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
E5E96_06510	ENOG4105CFQ	glutamine synthetase
E5E96_06515	ENOG4108V7X	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
E5E96_06530	ENOG4108RH0	Crea protein
E5E96_06535	ENOG4105C5I	Dehydrogenase
E5E96_06540	ENOG4105R8A	Heat shock protein
E5E96_06555	ENOG4107R28	alpha amylase, catalytic region
E5E96_06560	ENOG4105C5E	polysaccharide biosynthesis protein
E5E96_06565	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
E5E96_06575	ENOG4105DDQ	anthranilate synthase
E5E96_06610	ENOG4107TAE	Glycosyl transferase (Group 1
E5E96_06625	ENOG4105CND	Glycosyl transferase, family 2
E5E96_06640	ENOG4105CEY	Amp-dependent synthetase and ligase
E5E96_06645	ENOG4105CHR	reductase
E5E96_06660	ENOG4105F0R	Cytidylyltransferase
E5E96_06670	ENOG4105D2T	synthase
E5E96_06690	ENOG4105EQQ	protein containing aminopeptidase domain
E5E96_06725	ENOG4107R9T	Catalyzes the formation of 5-methyl-uridine at position 54 (m5U54) in all tRNAs (By similarity)
E5E96_06730	ENOG4107EXC	regulatoR
E5E96_06735	ENOG4105JJR	Histidine kinase
E5E96_06745	ENOG4105C6K	Malic enzyme
E5E96_06750	ENOG4105CGD	Nad-dependent epimerase dehydratase
E5E96_06755	ENOG4105VFB	Binds the 23S rRNA (By similarity)
E5E96_06760	ENOG4105C25	Primosomal protein n'
E5E96_06770	ENOG4105UYK	outer membrane protein a
E5E96_06775	ENOG4105C7B	Threonine dehydratase
E5E96_06780	ENOG4105C01	Dihydroxy-acid dehydratase
E5E96_06785	ENOG4105CM2	brancheD-chain amino acid aminotransferase
E5E96_06790	ENOG4105P3Y	Acetolactate synthase 2 regulatory subunit
E5E96_06805	ENOG4105C0P	Mg chelatase subunit ChlI
E5E96_06810	ENOG4106HNH	Acyl-transferase
E5E96_06815	ENOG4106HNH	Acyl-transferase
E5E96_06820	ENOG4105EWC	Purine nucleoside phosphorylase
E5E96_06830	ENOG4108RWI	nicotinamidase
E5E96_06835	ENOG4107RH7	Nicotinate phosphoribosyltransferase
E5E96_06840	ENOG4108Z33	Thiol disulfide Interchange Protein
E5E96_06845	ENOG4105E27	serine threonine protein kinase
E5E96_06855	ENOG4105PC1	Conserved Protein
E5E96_06875	ENOG4107QP2	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
E5E96_06880	ENOG4105ED0	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates (By similarity)
E5E96_06885	ENOG4105DSJ	YicC domain protein
E5E96_06905	ENOG4105W1T	Glycosyl Transferase
E5E96_06920	ENOG4105CUI	Catalyzes the interconversion between ADP-D-glycero- beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose (By similarity)
E5E96_06925	ENOG41062JF	Transcriptional regulator
E5E96_06930	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
E5E96_06935	ENOG4105CPQ	Dehydrogenase
E5E96_06940	ENOG4105MPD	Cytochrome
E5E96_06945	ENOG4105BZU	Histidine kinase
E5E96_06950	ENOG4105C4R	Atp-dependent dna helicase
E5E96_06955	ENOG4105C9B	Cysteine desulfurase
E5E96_06960	ENOG4105P9C	Participates in cysteine desulfuration mediated by SufS. Cysteine desulfuration mobilizes sulfur from L-cysteine to yield L-alanine and constitutes an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules. Functions as a sulfur acceptor for SufS, by mediating the direct transfer of the sulfur atom from the S-sulfanylcysteine of SufS, an intermediate product of cysteine desulfuration process (By similarity)
E5E96_06965	ENOG4105CUZ	uba thif-type nad fad binding protein
E5E96_07005	ENOG4105F03	Provides the (R)-glutamate required for cell wall biosynthesis (By similarity)
E5E96_07010	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
E5E96_07015	ENOG41063Z6	transcriptional regulator, lysR family
E5E96_07030	ENOG4108UM6	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity)
E5E96_07035	ENOG4105CY8	phosphoribosylaminoimidazole carboxylase atpase subunit
E5E96_07040	ENOG4105FCD	Major Facilitator
E5E96_07045	ENOG4105DY9	regulatoR
E5E96_07050	ENOG4108HRK	Histidine kinase
E5E96_07060	ENOG4105BZU	Histidine kinase
E5E96_07065	ENOG4107ZHV	Transcriptional regulator
E5E96_07070	ENOG4108GWT	fimbrillin MatB
E5E96_07075	ENOG4108NN8	Fimbrial protein
E5E96_07080	ENOG4108N3D	putative enzyme
E5E96_07100	ENOG4105EU0	Major facilitator Superfamily
E5E96_07105	ENOG4105CBX	hi0933 family
E5E96_07110	ENOG41090A1	ferritin
E5E96_07115	ENOG4105BZU	Histidine kinase
E5E96_07120	ENOG4105RKW	reductase (By
E5E96_07125	ENOG4108M6U	Universal stress protein A
E5E96_07155	ENOG4105EMK	carboxylate amino acid amine transporter
E5E96_07165	ENOG4108W7E	Catalyzes the ATP-dependent phosphorylation of the 3- deoxy-D-manno-octulosonic acid (Kdo) residue in Kdo-lipid IV(A) at the 4-OH position (By similarity)
E5E96_07170	ENOG4105DKP	glycosyl transferase, family 9
E5E96_07180	ENOG4105VFG	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity)
E5E96_07185	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
E5E96_07190	ENOG4105FE8	tRNA (Guanosine-2'-O-)-methyltransferase
E5E96_07195	ENOG4108EUD	Lysophospholipase
E5E96_07200	ENOG4105DQF	Hydrolase
E5E96_07230	ENOG4105Y7M	Transcriptional regulator, TetR family
E5E96_07235	ENOG410624X	efflux transporter, rnd family, mfp subunit
E5E96_07240	ENOG4105BZS	acriflavin resistance protein
E5E96_07245	ENOG4105BZU	Histidine kinase
E5E96_07250	ENOG4105DC8	reductase
E5E96_07275	ENOG4105D9K	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity)
E5E96_07280	ENOG4105C8X	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity)
E5E96_07285	ENOG4108R80	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions. The C subunit may be involved in assembly of the KDP complex (By similarity)
E5E96_07290	ENOG4105C08	Histidine kinase
E5E96_07295	ENOG4105EEX	Two component transcriptional regulator (Winged helix family
E5E96_07300	ENOG4105C2C	drug resistance transporter, Bcr CflA
E5E96_07315	ENOG4105JKW	Valine--pyruvate aminotransferase
E5E96_07320	ENOG4108ZNX	Heat shock protein
E5E96_07325	ENOG4108ZNX	Heat shock protein
E5E96_07330	ENOG4105D29	Helix-turn-helix type 11 domain protein
E5E96_07340	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
E5E96_07345	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
E5E96_07350	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
E5E96_07355	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
E5E96_07360	ENOG4105EAB	amino acid AbC transporter
E5E96_07365	ENOG4105E5Q	amino acid AbC transporter
E5E96_07370	ENOG4105CDA	abc transporter atp-binding protein
E5E96_07380	ENOG4105VG0	50S ribosomal protein l34
E5E96_07385	ENOG4105NVJ	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme (By similarity)
E5E96_07390	ENOG4105VAS	Could be involved in insertion of integral membrane proteins into the membrane (By similarity)
E5E96_07395	ENOG4105DHW	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
E5E96_07400	ENOG4105C1H	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity)
E5E96_07405	ENOG4105S6R	Iron-hydroxamate transporter permease subunit
E5E96_07420	ENOG4105IBP	Cyclic peptide transporter
E5E96_07425	ENOG4105E0K	tonB-dependent siderophore receptor
E5E96_07430	ENOG4105QTB	Flavodoxin
E5E96_07435	ENOG4107RE5	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity)
E5E96_07440	ENOG4105D28	Specifically methylates the N7 position of a guanine in 16S rRNA (By similarity)
E5E96_07445	ENOG4107QJE	Chromosome Partitioning Protein
E5E96_07450	ENOG4105FA0	parb-like partition protein
E5E96_07460	ENOG4105EE4	it plays a direct role in the translocation of protons across the membrane (By similarity)
E5E96_07465	ENOG4105KY6	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
E5E96_07470	ENOG4107Z6K	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
E5E96_07475	ENOG4107S15	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
E5E96_07480	ENOG4105CDG	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity)
E5E96_07485	ENOG4105J80	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity)
E5E96_07490	ENOG4105C4J	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity)
E5E96_07495	ENOG4105KNM	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
E5E96_07500	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
E5E96_07505	ENOG4105CT7	inner membrane cred family protein
E5E96_07520	ENOG4105E3W	Two component transcriptional regulator (Winged helix family
E5E96_07525	ENOG410804X	Transcriptional regulator
E5E96_07535	ENOG4105VJY	transcriptional regulator
E5E96_07555	ENOG4109015	Biopolymer transport protein exbD tolR
E5E96_07560	ENOG410822N	TonB family
E5E96_07600	ENOG4105DZC	cytosine deaminase
E5E96_07605	ENOG4105WMR	Protein CrcB homolog
E5E96_07615	ENOG4105JC1	sterol-binding domain protein
E5E96_07620	ENOG4105CNK	Required, probably indirectly, for the hydroxylation of 2-octaprenylphenol to 2-octaprenyl-6-hydroxy-phenol, the fourth step in ubiquinone biosynthesis (By similarity)
E5E96_07625	ENOG4105WKS	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity)
E5E96_07630	ENOG4105X8U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation (By similarity)
E5E96_07635	ENOG4105DCX	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity)
E5E96_07640	ENOG4105F8V	Hydrolase, tatD family
E5E96_07645	ENOG4105D52	delta-aminolevulinic acid dehydratase
E5E96_07650	ENOG4105DGW	oligopeptidase A
E5E96_07655	ENOG4105BZU	Histidine kinase
E5E96_07660	ENOG4105FFN	Specifically methylates the guanosine in position 1516 of 16S rRNA (By similarity)
E5E96_07675	ENOG4105C9X	ppx gppa phosphatase
E5E96_07680	ENOG4105C1J	atp-dependent rna helicase
E5E96_07690	ENOG4105C4P	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity)
E5E96_07700	ENOG4105D3H	Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol (By similarity)
E5E96_07705	ENOG4107QK7	reductase
E5E96_07710	ENOG4105W0Z	cytoplasmic protein
E5E96_07725	ENOG4105M78	Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide (By similarity)
E5E96_07740	ENOG4108IV0	ABC, transporter
E5E96_07745	ENOG4105C0Z	ABC transporter
E5E96_07750	ENOG4105CF8	branched-chain amino acid ABC transporter, permease
E5E96_07755	ENOG4105C32	Amino acid ABC transporter (Permease)
E5E96_07760	ENOG4105CP9	extracellular ligand-binding receptor
E5E96_07765	ENOG4105ETE	Transcriptional regulator (LacI family
E5E96_07770	ENOG4108JUA	Transcriptional regulator
E5E96_07775	ENOG4105CNW	domain protein
E5E96_07780	ENOG4108EQM	faD-dependent pyridine nucleotide-disulfide oxidoreductase
E5E96_07790	ENOG4105HEE	Binding Domain protein
E5E96_07795	ENOG4105CIC	tryptophan-specific transport protein
E5E96_07810	ENOG41072JS	exoenzyme T
E5E96_07830	ENOG4105KHV	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
E5E96_07840	ENOG4105C38	Glycyl-tRNA synthetase beta subunit
E5E96_07845	ENOG4108HMW	glycyl-tRNA synthetase, alpha subunit
E5E96_07850	ENOG4108R3E	Dna-3-methyladenine glycosylase i
E5E96_07855	ENOG4105C8Q	Methyl-accepting chemotaxis
E5E96_07860	ENOG4108ZG0	Ompa motb domain protein
E5E96_07865	ENOG4105M4H	endoribonuclease L-psp
E5E96_07870	ENOG41082K8	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Interacts with IscS and stimulates its activity. Then, accepts a sulfur from IscS and transfers it in turn to TusD (By similarity)
E5E96_07885	ENOG4105E0F	Histidine kinase
E5E96_07895	ENOG4105CHU	acetyl-coa acetyltransferase
E5E96_07900	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
E5E96_07905	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
E5E96_07910	ENOG4105D9Y	Splits dipeptides with a prolyl residue in the C- terminal position (By similarity)
E5E96_07915	ENOG4108ZK7	protein family UPF0029, Impact, N-terminal protein
E5E96_07920	ENOG4105D37	Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA (By similarity)
E5E96_07925	ENOG4108RR8	protoporphyrinogen oxidase
E5E96_07950	ENOG4105CD5	CoA-binding domain protein
E5E96_07965	ENOG4105EMY	transcriptional regulator
E5E96_07970	ENOG4105C6M	Alpha-keto-beta-hydroxylacyl reductoisomerase
E5E96_07975	ENOG4107QP8	phosphohexose isomerase
E5E96_07990	ENOG4105D64	Mechanosensitive ion channel
E5E96_07995	ENOG4105EC0	Required for nucleoid occlusion (NO) phenomenon, which prevents Z-ring formation and cell division over the nucleoid. Acts as a DNA-associated cell division inhibitor that binds simultaneously chromosomal DNA and FtsZ, and disrupts the assembly of FtsZ polymers. SlmA-DNA-binding sequences (SBS) are dispersed on non-Ter regions of the chromosome, preventing FtsZ polymerization at these regions (By similarity)
E5E96_08000	ENOG4108Z1K	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA (By similarity)
E5E96_08005	ENOG4105CJS	Phosphopantothenoylcysteine decarboxylase
E5E96_08010	ENOG4105W5Q	DNA repair protein (RadC
E5E96_08015	ENOG4105KDC	50s ribosomal protein l28
E5E96_08020	ENOG4105W0E	50S ribosomal protein L33
E5E96_08030	ENOG4105ERD	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity)
E5E96_08035	ENOG4108MJ5	VirK protein
E5E96_08040	ENOG4108ZEF	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity)
E5E96_08045	ENOG4105M5K	heptosyltransferase
E5E96_08050	ENOG4106WTF	Glycosyl transferase, family 2
E5E96_08055	ENOG4105XA0	heptosyltransferase ii
E5E96_08060	ENOG4105D8A	3-Deoxy-D-manno-octulosonic-acid transferase
E5E96_08080	ENOG4105DIQ	Transcriptional regulator
E5E96_08085	ENOG4105D3Z	quinone oxidoreductase, yhdh yhfp family
E5E96_08105	ENOG4105X6C	Flagellar basal body-associated protein FliL
E5E96_08110	ENOG4105VEI	Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4- hydroxybenzoate (4HB) for the ubiquinone pathway (By similarity)
E5E96_08115	ENOG4105C4G	Synthesis of 3-octaprenyl-4-hydroxybenzoate (By similarity)
E5E96_08120	ENOG4105E55	glycerol-3-phosphate acyltransferase
E5E96_08125	ENOG4105DS7	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity)
E5E96_08150	ENOG4107R73	Mate efflux family protein
E5E96_08155	ENOG4108UIQ	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity)
E5E96_08160	ENOG4105E0F	Histidine kinase
E5E96_08165	ENOG4105E3W	Two component transcriptional regulator (Winged helix family
E5E96_08175	ENOG4105D7W	serine acetyltransferase
E5E96_08185	ENOG41065UX	Non-essential, abundant cell division factor that is required for proper Z-ring formation. It is recruited early to the divisome by direct interaction with FtsZ, stimulating Z-ring assembly and thereby promoting cell division earlier in the cell cycle. Its recruitment to the Z-ring requires functional FtsA or ZipA (By similarity)
E5E96_08190	ENOG4108556	Isoprenoid biosynthesis protein with amidotransferase-like domain
E5E96_08195	ENOG4105C2M	dna polymerase I
E5E96_08200	ENOG4108Z0R	Transferase
E5E96_08235	ENOG4105CQ4	Transcriptional regulator
E5E96_08240	ENOG4105CNT	hydrolase family 2
E5E96_08245	ENOG4105FK9	beta-D-galactosidase beta subunit
E5E96_08250	ENOG4105E5D	amino acid
E5E96_08255	ENOG4108Y51	tRNA-binding protein
E5E96_08260	ENOG4105E5D	amino acid
E5E96_08265	ENOG4105DHU	Bile acid
E5E96_08270	ENOG4105E46	N-alpha,N-alpha,N-alpha-trimethyl-L-histidine metabolic process
E5E96_08290	ENOG4105CC0	LysR family Transcriptional regulator
E5E96_08300	ENOG4105UIB	(ABC) transporter
E5E96_08305	ENOG4108JQ9	ABC transporter
E5E96_08310	ENOG4105DIH	basic membrane
E5E96_08315	ENOG4105C4R	Atp-dependent dna helicase
E5E96_08325	ENOG4105C4Q	deoxyguanosinetriphosphate triphosphohydrolase-like protein
E5E96_08330	ENOG4108UK5	Transposase
E5E96_08350	ENOG41061EV	selenium-binding protein YdfZ
E5E96_08375	ENOG4108YH8	Covalently attaches a chromophore to Cys residue(s) of phycobiliproteins (By similarity)
E5E96_08385	ENOG410829K	Lysine exporter protein (Lyse ygga)
E5E96_08390	ENOG4105CUC	YeeE YedE family protein
E5E96_08395	ENOG4108N3W	hemolysin secretion protein
E5E96_08400	ENOG4105C52	Atpase, p-type (Transporting), had superfamily, subfamily ic
E5E96_08405	ENOG4105CCF	Lysine exporter protein (Lyse ygga)
E5E96_08410	ENOG4105ECQ	AraC Family Transcriptional Regulator
E5E96_08415	ENOG4105FR1	rard protein
E5E96_08425	ENOG4105C26	Dehydrogenase
E5E96_08430	ENOG4108JCI	Transcriptional regulator
E5E96_08440	ENOG4105C26	Dehydrogenase
E5E96_08445	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
E5E96_08450	ENOG4105DCF	alanine dehydrogenase
E5E96_08455	ENOG4105D7K	pfkb domain protein
E5E96_08475	ENOG4105CGY	Dna recombination protein
E5E96_08480	ENOG4105D37	Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA (By similarity)
E5E96_08485	ENOG4105C1A	potassium transporter peripheral membrane
E5E96_08490	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
E5E96_08495	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
E5E96_08500	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
E5E96_08510	ENOG4105C79	DNA protecting protein DprA
E5E96_08515	ENOG4108RPN	Protein smg homolog
E5E96_08520	ENOG4108WI1	Dna topoisomerase
E5E96_08530	ENOG4105EK0	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
E5E96_08535	ENOG4105DBS	Key enzyme in heme biosynthesis. Catalyzes the oxidative decarboxylation of propionic acid side chains of rings A and B of coproporphyrinogen III (By similarity)
E5E96_08540	ENOG4105E2X	shikimate dehydrogenase
E5E96_08545	ENOG4105SG3	Protein of unknown function (DUF1488)
E5E96_08550	ENOG4105WHM	Necessary for normal cell division and for the maintenance of normal septation (By similarity)
E5E96_08555	ENOG4106RE7	Cytochrome
E5E96_08565	ENOG4105ZR3	A GTPase-activating protein (GAP) that modifies Der EngA GTPase function. May play a role in ribosome biogenesis (By similarity)
E5E96_08570	ENOG4105XCT	Protein of unknown function (DUF2489)
E5E96_08575	ENOG4105D4P	Coproporphyrinogen iii oxidase
E5E96_08580	ENOG4105EKD	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism (By similarity)
E5E96_08585	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
E5E96_08590	ENOG4105CUX	Signal transduction histidine kinase
E5E96_08600	ENOG4105C5F	glutamine synthetase
E5E96_08605	ENOG4105CI3	gtp-binding protein typa
E5E96_08610	ENOG4107S2Z	UPF0761 membrane protein
E5E96_08615	ENOG4108YYA	Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine (By similarity)
E5E96_08625	ENOG4105SUU	thioesterase domain
E5E96_08635	ENOG4105CB5	ATP-dependent DNA helicase recG
E5E96_08640	ENOG4105JIM	Phosphatidylserine synthase
E5E96_08645	ENOG4105C6Z	Gluconate
E5E96_08650	ENOG4108Z67	carbohydrate kinase, thermoresistant glucokinase family
E5E96_08655	ENOG4105C01	Dihydroxy-acid dehydratase
E5E96_08660	ENOG4108UHU	Aldolase
E5E96_08665	ENOG4105DIQ	Transcriptional regulator
E5E96_08675	ENOG41063SB	peptidase
E5E96_08680	ENOG4105CJI	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
E5E96_08685	ENOG4107YZP	Rhodanese domain protein
E5E96_08690	ENOG4105IX2	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA (By similarity)
E5E96_08695	ENOG4105CSF	NADPH-dependent glycerol-3-phosphate dehydrogenase
E5E96_08700	ENOG4107RUK	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins (By similarity)
E5E96_08710	ENOG4105D3C	The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters (By similarity)
E5E96_08730	ENOG4105BZM	domain protein
E5E96_08735	ENOG4108RRZ	Transcription elongation factor GreB
E5E96_08745	ENOG4105E0F	Histidine kinase
E5E96_08755	ENOG4108Z10	Involved in the binding of tRNA to the ribosomes (By similarity)
E5E96_08760	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
E5E96_08765	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
E5E96_08770	ENOG41080KG	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
E5E96_08775	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
E5E96_08780	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
E5E96_08785	ENOG4105KAP	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity)
E5E96_08790	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
E5E96_08795	ENOG4108R70	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity)
E5E96_08800	ENOG41083MP	50s ribosomal protein l29
E5E96_08805	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
E5E96_08810	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
E5E96_08815	ENOG4105KAR	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity)
E5E96_08820	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
E5E96_08825	ENOG4105VBI	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
E5E96_08830	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
E5E96_08835	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
E5E96_08840	ENOG4105K4C	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity)
E5E96_08845	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
E5E96_08850	ENOG4105VPB	50S ribosomal protein L30
E5E96_08855	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
E5E96_08860	ENOG4105CGG	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity)
E5E96_08865	ENOG41067V7	50S ribosomal protein L36
E5E96_08870	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
E5E96_08875	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
E5E96_08880	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
E5E96_08885	ENOG4105CTF	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
E5E96_08890	ENOG4108ZT0	50S ribosomal protein l17
E5E96_08940	ENOG4105CKD	glutathione-regulated potassium-efflux system protein
E5E96_08945	ENOG4108K2R	Glutathione-regulated potassium-efflux system ancillary protein
E5E96_08950	ENOG4108W5M	transcriptional regulator
E5E96_08955	ENOG4105EMU	Dehydrogenase
E5E96_08970	ENOG4105CUG	Oligopeptidase b
E5E96_08995	ENOG4107FS9	Membrane
E5E96_09010	ENOG4105JQN	Transcriptional regulator
E5E96_09025	ENOG4105VVZ	metal-binding protein
E5E96_09030	ENOG41076UM	multiple antibiotic resistance (MarC)-related protein
E5E96_09050	ENOG4105E4C	Lytic transglycosylase catalytic
E5E96_09055	ENOG4107RZC	phospholipase d
E5E96_09065	ENOG4105EJ2	Transcriptional regulator
E5E96_09080	ENOG4106H78	methyltransferase
E5E96_09085	ENOG4105CCP	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
E5E96_09090	ENOG4105CAK	Cell division ATP-binding protein ftsE
E5E96_09095	ENOG4105CRP	Part of the ABC transporter FtsEX involved in
E5E96_09105	ENOG41077A9	carbonic anhydrase
E5E96_09110	ENOG4105CZE	histidine utilization repressor
E5E96_09115	ENOG4105CI2	imidazolone-5-propionate hydrolase
E5E96_09120	ENOG41088SP	formiminoglutamate hydrolase
E5E96_09125	ENOG4105CGP	Urocanate hydratase
E5E96_09130	ENOG4105C84	Histidine ammonia-lyase
E5E96_09135	ENOG4105EWV	Sodium calcium exchanger membrane region
E5E96_09140	ENOG4107XTP	(EAL) domain protein
E5E96_09145	ENOG41062P1	Diguanylate cyclase phosphodiesterase
E5E96_09175	ENOG4105GVR	general secretion pathway protein D
E5E96_09190	ENOG4107QHF	type ii secretion system protein e
E5E96_09195	ENOG4105D7Q	type ii secretion system
E5E96_09210	ENOG4108VAU	general secretion pathway protein G
E5E96_09245	ENOG4105N3I	Involved in formation and maintenance of cell shape (By similarity)
E5E96_09250	ENOG4105VQ7	Rod shape-determining protein MreD
E5E96_09255	ENOG4108Z03	MAF-like protein
E5E96_09265	ENOG4105QD6	exported protein
E5E96_09280	ENOG4105D1U	peptidase U62 modulator of DNA gyrase
E5E96_09285	ENOG4108PSC	Represses the expression of the murPQ operon involved in the uptake and degradation of N-acetylmuramic acid (MurNAc). Binds to two adjacent inverted repeats within the operator region. MurNAc 6-phosphate, the substrate of MurQ, is the specific inducer that weakens binding of MurR to the operator (By similarity)
E5E96_09305	ENOG4105C5Y	PTS System
E5E96_09310	ENOG4105E15	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
E5E96_09325	ENOG4105CSH	Transporter
E5E96_09335	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
E5E96_09340	ENOG4105BZU	Histidine kinase
E5E96_09345	ENOG4105QD0	anti-sigma regulatory factor serine threonine protein kinase
E5E96_09350	ENOG4107MMM	Anti-sigma-factor antagonist
E5E96_09355	ENOG4107SDU	Methyl-accepting chemotaxis
E5E96_09370	ENOG4105F0S	class B acid phosphatase
E5E96_09375	ENOG4105CGZ	zinc metallopeptidase
E5E96_09385	ENOG4108HU6	Metal dependent phosphohydrolase
E5E96_09400	ENOG4105EEQ	Na H antiporter
E5E96_09405	ENOG4105C3R	Methionine synthase
E5E96_09410	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
E5E96_09425	ENOG4105ETX	regulatoR
E5E96_09435	ENOG4108MR7	Arylsulfotransferase
E5E96_09440	ENOG4105CBF	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction (By similarity)
E5E96_09445	ENOG4108UV6	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity)
E5E96_09450	ENOG4105D06	uba thif-type nad fad binding protein
E5E96_09460	ENOG4105CA8	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity)
E5E96_09465	ENOG4105D41	biosynthesis protein thiH
E5E96_09485	ENOG4105EQK	-acetyltransferase
E5E96_09490	ENOG4108WEF	Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1B (PBP1b) (By similarity)
E5E96_09510	ENOG4105BZU	Histidine kinase
E5E96_09515	ENOG4105C44	Serine transporter
E5E96_09520	ENOG4108TPP	exopolysaccharide synthesis
E5E96_09535	ENOG4105N0V	mono-oxygenase ydhR
E5E96_09540	ENOG4105KVH	Transcriptional regulator
E5E96_09565	ENOG4105E0K	tonB-dependent siderophore receptor
E5E96_09580	ENOG4105CBT	Fructose-1,6-bisphosphatase
E5E96_09595	ENOG4105ECF	c-methyltransferase
E5E96_09600	ENOG41076E6	Uroporphyrinogen-III Synthase
E5E96_09605	ENOG4105D6W	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity)
E5E96_09610	ENOG4107T0K	Adenylate cyclase
E5E96_09615	ENOG4106CJB	Phospholipase Carboxylesterase
E5E96_09620	ENOG4105XQ6	frataxin-like protein
E5E96_09630	ENOG4105CU5	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity)
E5E96_09635	ENOG4105E4Z	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan (By similarity)
E5E96_09645	ENOG4108IYS	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
E5E96_09650	ENOG4105DFC	had-superfamily hydrolase, subfamily ia, variant
E5E96_09660	ENOG4107RYR	Transcriptional regulator, Crp Fnr family
E5E96_09670	ENOG4108Z86	Glutamine amidotransferase
E5E96_09675	ENOG410667J	hydrolase
E5E96_09690	ENOG4105CJ1	ABC, transporter
E5E96_09700	ENOG4108I62	cina-like protein
E5E96_09705	ENOG4105E4Y	Endoribonuclease that initiates mRNA decay (By similarity)
E5E96_09710	ENOG4105CVG	Homoserine O-transsuccinylase
E5E96_09720	ENOG4108YXU	transcriptional regulator AsnC family
E5E96_09725	ENOG4105E0M	Sulfatase
E5E96_09745	ENOG4105KT7	mgtC SapB transporter
E5E96_09765	ENOG4105EMU	Dehydrogenase
E5E96_09770	ENOG4105DZW	Dipeptidase
E5E96_09795	ENOG4108IQK	o-acetylhomoserine
E5E96_09805	ENOG4105KNR	Activates the small RNA gene sgrS under glucose- phosphate stress conditions as well as yfdZ. Represses its own transcription under both stress and non-stress conditions. Might act as a sensor of the intracellular accumulation of phosphoglucose by binding these molecules in its C-terminal solute-binding domain (By similarity)
E5E96_09825	ENOG4107IFA	Lipase (EC 3.1.1.3)
E5E96_09840	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
E5E96_09845	ENOG4108UB4	uncharacterized protein ygjQ
E5E96_09850	ENOG4107MM9	BNR Asp-box repeat-containing protein
E5E96_09860	ENOG4105HMV	Fimbrial protein
E5E96_09870	ENOG4106PG1	outer membrane usher protein
E5E96_09875	ENOG4108FZ9	Chaperone
E5E96_09880	ENOG4108MDY	Fimbrial
E5E96_09895	ENOG4105CEY	Amp-dependent synthetase and ligase
E5E96_09905	ENOG4108IPT	Naphthoate synthase
E5E96_09910	ENOG4107J5P	Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC). Is also able to catalyze the hydrolysis of the thioester bond in palmitoyl-CoA in vitro (By similarity)
E5E96_09920	ENOG4105E4F	Isochorismate synthase
E5E96_09925	ENOG4105EIS	1,4-dihydroxy-2-naphthoate octaprenyltransferase
E5E96_09950	ENOG4105C1J	atp-dependent rna helicase
E5E96_09955	ENOG4105D9N	nucleoside
E5E96_09960	ENOG4107K5X	Membrane-bound metal-dependent hydrolase
E5E96_09975	ENOG4108UPT	UPF0178 protein
E5E96_10000	ENOG4105C3N	Participates in control of cell volume in low-osmolarity conditions (By similarity)
E5E96_10005	ENOG4105E61	Mannitol repressor protein
E5E96_10010	ENOG4107SQ3	mannitol-1-phosphate 5-dehydrogenase
E5E96_10015	ENOG4105CTS	PTS system mannitol-specific
E5E96_10030	ENOG4108IEC	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction (By similarity)
E5E96_10035	ENOG4105CXD	Specific inhibitor of chromosomal initiation of replication in vitro. Binds the three 13-mers in the origin (oriC) to block initiation of replication (By similarity)
E5E96_10040	ENOG4105NNS	Autoinducer synthesis protein
E5E96_10045	ENOG4105VJY	transcriptional regulator
E5E96_10050	ENOG4108ZUB	Lysine exporter protein (Lyse ygga)
E5E96_10055	ENOG4107RNS	bifunctional 2',3'-cyclic nucleotide 2'-phosphodiesterase 3'-nucleotidase periplasmic
E5E96_10060	ENOG4108XTF	Outer Membrane Lipoprotein
E5E96_10070	ENOG4105VXR	cytoplasmic protein
E5E96_10085	ENOG4105DJ1	Phosphoenolpyruvate Carboxylase
E5E96_10090	ENOG4105F4C	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress (By similarity)
E5E96_10095	ENOG4105VEJ	Heat shock protein
E5E96_10105	ENOG4105GVR	general secretion pathway protein D
E5E96_10110	ENOG4107QHF	type ii secretion system protein e
E5E96_10115	ENOG4105D7Q	type ii secretion system
E5E96_10120	ENOG4108VAU	general secretion pathway protein G
E5E96_10175	ENOG4108UDW	Transcriptional regulator, luxr family
E5E96_10180	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
E5E96_10185	ENOG4107Y3D	HAD-superfamily hydrolase subfamily IA variant 3
E5E96_10190	ENOG4107RK2	ADP-ribose diphosphatase NudE
E5E96_10195	ENOG4108RNI	3'(2')5'-bisphosphate nucleotidase
E5E96_10200	ENOG4105C44	Serine transporter
E5E96_10205	ENOG4108Z7R	Chaperone CsaA
E5E96_10210	ENOG41086D8	Transcriptional regulator
E5E96_10215	ENOG4105GGQ	This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis (By similarity)
E5E96_10220	ENOG4105C28	cystathionine
E5E96_10225	ENOG4105CFH	Aspartokinase
E5E96_10235	ENOG4105CCA	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle (By similarity)
E5E96_10245	ENOG4105C0N	N-acetylglutamate semialdehyde dehydrogenase
E5E96_10250	ENOG4105CAS	nag kinase
E5E96_10260	ENOG4105CDH	Citrulline--aspartate ligase
E5E96_10265	ENOG4105CH7	arginosuccinase
E5E96_10285	ENOG4108UW5	maltose o-acetyltransferase
E5E96_10290	ENOG4107PU6	Membrane
E5E96_10295	ENOG4105DE7	Sulfate ABC transporter periplasmic sulfate-binding protein
E5E96_10305	ENOG4108I5D	sulfate abc transporter
E5E96_10310	ENOG4105ECW	sulfate abc transporter
E5E96_10315	ENOG4108IJ6	ABC transporter
E5E96_10320	ENOG4107R11	Transcriptional regulator
E5E96_10325	ENOG4108M1A	Chitin-binding protein
E5E96_10330	ENOG4108N3W	hemolysin secretion protein
E5E96_10365	ENOG4107RE3	peptidase, S41
E5E96_10385	ENOG4105G0K	glycine radical enzyme YjjI family
E5E96_10390	ENOG41076CZ	activating enzyme
E5E96_10405	ENOG4105CGF	Aromatic amino acid aminotransferase
E5E96_10435	ENOG4108V1J	Has antioxidant activity. Could remove peroxides or H(2)O(2) (By similarity)
E5E96_10445	ENOG4105C1J	atp-dependent rna helicase
E5E96_10460	ENOG4108QYW	Bacterial hemolysins are exotoxins that attack blood cell membranes and cause cell rupture. Beta-hemolysin is a phospholipase C with specific activity toward sphingomyelins. Has a high specificity for sphingomyelin, hydrolyzes lysophosphatidylcholine at a much lower rate, but has no activity towards phosphatidylcholine, phosphatidylethanolamine, or phosphatidylserine (By similarity)
E5E96_10465	ENOG4107RHT	methyl-accepting chemotaxis sensory transducer with Pas Pac sensor
E5E96_10480	ENOG4105XTV	UPF0231 protein
E5E96_10485	ENOG4108IXP	Carbohydrate diacid transcriptional activator CdaR
E5E96_10490	ENOG4107QQ0	gntp family
E5E96_10495	ENOG4105BZW	Glycerate kinase
E5E96_10510	ENOG4105HEI	LysR family (Transcriptional regulator
E5E96_10515	ENOG4105D9N	nucleoside
E5E96_10525	ENOG4108YZN	class I peptide chain release factor
E5E96_10530	ENOG4108YZA	Nitrogen regulatory protein pii
E5E96_10545	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
E5E96_10555	ENOG410682Y	Regulates arginine biosynthesis genes (By similarity)
E5E96_10565	ENOG4106PMH	Extracellular solute-binding protein family 3
E5E96_10570	ENOG4105GBT	ABC transporter
E5E96_10575	ENOG4105DMR	ABC, transporter
E5E96_10580	ENOG4105C80	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
E5E96_10585	ENOG4108UV7	flagellar protein motX
E5E96_10590	ENOG4105CJJ	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity)
E5E96_10600	ENOG4108JU6	CBS domain protein
E5E96_10605	ENOG4106KVJ	cytochrome C assembly protein
E5E96_10610	ENOG4105CB9	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
E5E96_10615	ENOG4105K5M	30s ribosomal protein S16
E5E96_10620	ENOG4108ZR6	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity)
E5E96_10625	ENOG4105D6X	Specifically methylates guanosine-37 in various tRNAs (By similarity)
E5E96_10630	ENOG4108YY1	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity)
E5E96_10640	ENOG4105IRT	Sequence-specific endonuclease that cleaves unmethylated GATC sequences. It is involved in DNA mismatch repair (By similarity)
E5E96_10645	ENOG4105EJF	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity)
E5E96_10650	ENOG4108HRM	phosphoenolpyruvate--protein phosphotransferase
E5E96_10655	ENOG4105C3B	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity)
E5E96_10660	ENOG4105C0V	Provides the sole de novo source of dTMP for DNA biosynthesis (By similarity)
E5E96_10665	ENOG4105DRC	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity)
E5E96_10675	ENOG41063Z6	transcriptional regulator, lysR family
E5E96_10680	ENOG41080HT	Transcriptional regulator, arsr family
E5E96_10685	ENOG4105KQV	Binds directly to 16S ribosomal RNA (By similarity)
E5E96_10690	ENOG4105CJR	Integral membrane protein (MviN
E5E96_10695	ENOG4105DTN	riboflavin biosynthesis protein ribF
E5E96_10700	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
E5E96_10705	ENOG4105M02	This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity)
E5E96_10710	ENOG41090X3	Peptidyl-prolyl cis-trans isomerase
E5E96_10715	ENOG4105C48	Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) (By similarity)
E5E96_10775	ENOG4105C4K	Nad synthetase
E5E96_10780	ENOG4108YZA	Nitrogen regulatory protein pii
E5E96_10790	ENOG4106762	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD) (By similarity)
E5E96_10795	ENOG4106TD9	Diguanylate cyclase
E5E96_10800	ENOG4105C40	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity)
E5E96_10805	ENOG4107UNZ	domain protein
E5E96_10810	ENOG4105JPW	Domain of unknown function (DUF1837)
E5E96_10815	ENOG4105C2N	RNA methyltransferase TrmH family group 3
E5E96_10840	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
E5E96_10845	ENOG4105C56	H( )-stimulated, divalent metal cation uptake system (By similarity)
E5E96_10850	ENOG4108ZDX	Binds together with S18 to 16S ribosomal RNA (By similarity)
E5E96_10855	ENOG4105VH8	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity)
E5E96_10860	ENOG4105K9Q	Binds to the 23S rRNA (By similarity)
E5E96_10865	ENOG4105DP0	ferredoxin-NADP reductase
E5E96_10890	ENOG4105W39	Membrane
E5E96_10900	ENOG4105D9M	gamma-glutamylcysteine synthetase
E5E96_10910	ENOG4108IQE	Amp-dependent synthetase and ligase
E5E96_10920	ENOG41080E2	ribosomal-protein-alanine acetyltransferase
E5E96_10930	ENOG4107R4Q	Functions as an ATPase. May play a role in metal insertion (metal-chelatase) or as a chaperone (By similarity)
E5E96_10940	ENOG4105BZU	Histidine kinase
E5E96_10975	ENOG4108MJ3	acetyltransferase
E5E96_10980	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
E5E96_10995	ENOG4105DWY	Agmatine deiminase
E5E96_11000	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
E5E96_11035	ENOG4105C1J	atp-dependent rna helicase
E5E96_11040	ENOG4107Y60	(LipO)protein
E5E96_11050	ENOG4106B0W	Curli production assembly transport component CsgG
E5E96_11070	ENOG4107V4F	S-adenosyl-l-methionine hydroxide adenosyltransferase
E5E96_11075	ENOG4105CA0	peroxidase
E5E96_11100	ENOG4105EA8	2-Nitropropane dioxygenase
E5E96_11130	ENOG4105E09	nadh pyrophosphatase
E5E96_11135	ENOG4105E0F	Histidine kinase
E5E96_11140	ENOG4105E3W	Two component transcriptional regulator (Winged helix family
E5E96_11145	ENOG4105DJY	efflux transporter, rnd family, mfp subunit
E5E96_11150	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
E5E96_11155	ENOG4105CT1	(ABC) transporter
E5E96_11160	ENOG4105CDA	abc transporter atp-binding protein
E5E96_11165	ENOG4105E5Q	amino acid AbC transporter
E5E96_11170	ENOG4105E5Q	amino acid AbC transporter
E5E96_11175	ENOG4108IYI	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine (By similarity)
E5E96_11200	ENOG4105CYX	Short-chain dehydrogenase reductase Sdr
E5E96_11205	ENOG4105CE6	Adenylation and deadenylation of glutamate--ammonia ligase (By similarity)
E5E96_11215	ENOG4105C8Q	Methyl-accepting chemotaxis
E5E96_11220	ENOG4105EYW	Ion transport protein
E5E96_11225	ENOG4106MWK	domain protein
E5E96_11230	ENOG4105C26	Dehydrogenase
E5E96_11235	ENOG4105E09	nadh pyrophosphatase
E5E96_11240	ENOG4105CFZ	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III (By similarity)
E5E96_11245	ENOG4105DKQ	ROK family
E5E96_11250	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
E5E96_11255	ENOG4105BZA	Phosphoglycerate kinase
E5E96_11260	ENOG4105D2N	Aldolase
E5E96_11265	ENOG4105CJP	fad dependent oxidoreductase
E5E96_11275	ENOG4105CSG	Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps (By similarity)
E5E96_11305	ENOG4105Y75	tpr repeat protein
E5E96_11315	ENOG4108IYU	L-aspartate oxidase
E5E96_11320	ENOG4105EMN	RNA polymerase sigma factor
E5E96_11325	ENOG41069PW	sigma-e factor negative regulatory protein
E5E96_11340	ENOG4105C4S	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity)
E5E96_11345	ENOG4105C3F	Signal peptidase i
E5E96_11360	ENOG41071DT	Involved in DNA repair and RecF pathway recombination (By similarity)
E5E96_11365	ENOG4105CSZ	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate (By similarity)
E5E96_11375	ENOG4105D2N	Aldolase
E5E96_11380	ENOG4105CE4	GlcNAc 6-P deacetylase
E5E96_11385	ENOG4108YTN	IIa component
E5E96_11390	ENOG4105F3R	pts system mannose fructose sorbose family iid
E5E96_11400	ENOG4108RG5	PTS system N-acetylgalactosamine-specific transporter subunit IIB
E5E96_11405	ENOG4105E70	isomerase
E5E96_11410	ENOG4105C6Q	that is required for full activity and stability of the Y subunit. Could have a chaperone-like function for the proper and stable folding of
E5E96_11415	ENOG4105E98	transcriptional regulator DeoR family
E5E96_11420	ENOG4108VBV	N-Acetylmuramoyl-L-alanine amidase
E5E96_11425	ENOG4108W15	Protein of unknown function (DUF1456)
E5E96_11430	ENOG4105BZU	Histidine kinase
E5E96_11435	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
E5E96_11440	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
E5E96_11445	ENOG4105DXN	mazG family
E5E96_11450	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
E5E96_11455	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
E5E96_11460	ENOG4105XX3	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity)
E5E96_11465	ENOG4105CE5	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) (By similarity)
E5E96_11470	ENOG4108UH8	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (By similarity)
E5E96_11475	ENOG4106NZV	Responsible for synthesis of pseudouridine from uracil- 13 in transfer RNAs (By similarity)
E5E96_11480	ENOG4105CV2	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates (By similarity)
E5E96_11485	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
E5E96_11490	ENOG4108UM1	dedA family
E5E96_11495	ENOG4108K5P	(LipO)protein
E5E96_11505	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
E5E96_11510	ENOG4105VCC	30S ribosomal protein S21
E5E96_11515	ENOG4105KTH	gatB Yqey
E5E96_11520	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
E5E96_11525	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
E5E96_11550	ENOG4105C12	Phosphoribosylglycinamide synthetase
E5E96_11555	ENOG4105DC1	bifunctional purine biosynthesis protein purh
E5E96_11565	ENOG4105NAE	bifunctional deaminase-reductase domain protein
E5E96_11575	ENOG4105CSA	Coproporphyrinogen iii oxidase
E5E96_11580	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
E5E96_11590	ENOG4105D9R	oxidoreductase
E5E96_11600	ENOG4105D9U	N-acetyltransferase
E5E96_11605	ENOG4108Z9I	-acetyltransferase
E5E96_11620	ENOG4105EV4	Multidrug resistance protein mdtH
E5E96_11630	ENOG4105DS2	Anaerobic c4-dicarboxylate transporter
E5E96_11635	ENOG4108IJ0	Aspartate ammonia-lyase
E5E96_11640	ENOG4108YH1	overproduction of this protein in Escherichia coli inhibits the F plasmid-mediated exclusion of bacteriophage T7
E5E96_11650	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
E5E96_11655	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
E5E96_11665	ENOG4105BZU	Histidine kinase
E5E96_11675	ENOG4105D3G	Pseudouridine synthase
E5E96_11680	ENOG4105BZK	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair (By similarity)
E5E96_11720	ENOG4108IAB	Phoh family
E5E96_11725	ENOG4107T0D	ABC, transporter
E5E96_11730	ENOG4106SMU	thiamine transporter membrane protein
E5E96_11735	ENOG4105DP9	ABC transporter
E5E96_11750	ENOG4105MQS	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
E5E96_11755	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
E5E96_11765	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
E5E96_11775	ENOG4105YVM	Phosphoesterase, PA-phosphatase related
E5E96_11790	ENOG4105C7K	acetolactate synthase
E5E96_11795	ENOG4108ZP8	Acetolactate synthase small subunit
E5E96_11800	ENOG4105C6K	Malic enzyme
E5E96_11805	ENOG4105C6H	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity)
E5E96_11815	ENOG4105XWI	UPF0304 protein
E5E96_11820	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
E5E96_11825	ENOG4105RH4	Glycine cleavage system transcriptional repressor
E5E96_11830	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
E5E96_11835	ENOG4107EG0	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
E5E96_11840	ENOG4107QWK	SAICAR synthetase
E5E96_11850	ENOG4105EXG	Transcriptional regulator
E5E96_11855	ENOG4106173	Uncharacterized protein conserved in bacteria (DUF2057)
E5E96_11875	ENOG4105BZU	Histidine kinase
E5E96_11880	ENOG4105C4Q	deoxyguanosinetriphosphate triphosphohydrolase-like protein
E5E96_11890	ENOG4105BZU	Histidine kinase
E5E96_11895	ENOG4105BZU	Histidine kinase
E5E96_11900	ENOG4108N3W	hemolysin secretion protein
E5E96_11920	ENOG4105MDZ	Transcriptional activator rfaH
E5E96_11925	ENOG4105D01	(LipO)protein
E5E96_11930	ENOG4108UMI	ABC transporter, permease
E5E96_11935	ENOG4108JEI	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity)
E5E96_11950	ENOG4105EH2	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity)
E5E96_11955	ENOG4105DR1	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)
E5E96_11960	ENOG4105K8N	protein family UPF0079, ATPase
E5E96_11965	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
E5E96_11970	ENOG4105DC6	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity)
E5E96_11975	ENOG4105DKX	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity)
E5E96_11980	ENOG4105KW8	RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity)
E5E96_11985	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
E5E96_11990	ENOG4107QJR	hflk protein
E5E96_11995	ENOG4105EPW	hflc protein
E5E96_12005	ENOG4105EAH	synthase
E5E96_12010	ENOG4105KK9	This protein binds to 23S rRNA in the presence of protein L20 (By similarity)
E5E96_12015	ENOG4105K46	50S ribosomal protein l27
E5E96_12020	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
E5E96_12025	ENOG4105DWD	nucleoside recognition domain protein
E5E96_12030	ENOG4105CEY	Amp-dependent synthetase and ligase
E5E96_12045	ENOG4108ESY	Metal dependent phosphohydrolase
E5E96_12050	ENOG4105DEN	Luciferase family
E5E96_12060	ENOG4105DDT	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP (By similarity)
E5E96_12070	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
E5E96_12075	ENOG4105CEZ	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) (By similarity)
E5E96_12085	ENOG4105E7H	involved in the assembly of LPS in the outer leaflet of the outer membrane. Determines N-hexane tolerance and is involved in outer membrane permeability. Essential for envelope biogenesis (By similarity)
E5E96_12090	ENOG4105EHM	Aminoglycoside phosphotransferase
E5E96_12095	ENOG4108S0S	Nucleotidyl transferase
E5E96_12100	ENOG41066UG	Regulatory DnaK co-chaperone. Direct interaction between DnaK and DjlA is needed for the induction of the wcaABCDE operon, involved in the synthesis of a colanic acid polysaccharide capsule, possibly through activation of the RcsB RcsC phosphotransfer signaling pathway. The colanic acid capsule may help the bacterium survive conditions outside the host (By similarity)
E5E96_12105	ENOG4105C7N	Xanthine uracil vitamin C permease
E5E96_12115	ENOG4105C5H	ABC transporter
E5E96_12130	ENOG4105DUF	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively (By similarity)
E5E96_12135	ENOG4105E4C	Lytic transglycosylase catalytic
E5E96_12155	ENOG4107U5R	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate (By similarity)
E5E96_12160	ENOG4105D9N	nucleoside
E5E96_12190	ENOG4105EHG	Permease protein
E5E96_12200	ENOG41090JE	Utilization Protein
E5E96_12205	ENOG4105PYN	Pyridoxamine 5-phosphate oxidase-related
E5E96_12225	ENOG4105D05	Receptor
E5E96_12235	ENOG4105D8G	Major Facilitator superfamily
E5E96_12240	ENOG4105VMP	Transcriptional regulator
E5E96_12250	ENOG4105BZU	Histidine kinase
E5E96_12260	ENOG4108MA4	Peptidase M66
E5E96_12265	ENOG4108M1A	Chitin-binding protein
E5E96_12270	ENOG4105DHI	Methyltransferase
E5E96_12275	ENOG4107RYR	Transcriptional regulator, Crp Fnr family
E5E96_12280	ENOG4108UKZ	OsmC family
E5E96_12295	ENOG4105CJE	phosphoribulokinase (EC 2.7.1.19)
E5E96_12300	ENOG4105PE8	Translocates 4-amino-4-deoxy-L-arabinose- phosphoundecaprenol (alpha-L-Ara4N-phosphoundecaprenol) from the cytoplasmic to the periplasmic side of the inner membrane (By similarity)
E5E96_12305	ENOG41060GT	Translocates 4-amino-4-deoxy-L-arabinose- phosphoundecaprenol (alpha-L-Ara4N-phosphoundecaprenol) from the cytoplasmic to the periplasmic side of the inner membrane (By similarity)
E5E96_12310	ENOG4105SA9	Catalyzes the transfer of the L-Ara4N moiety of the glycolipid undecaprenyl phosphate-alpha-L-Ara4N to lipid A. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides (By similarity)
E5E96_12315	ENOG4105F73	Catalyzes the deformylation of 4-deoxy-4-formamido-L- arabinose-phosphoundecaprenol to 4-amino-4-deoxy-L-arabinose- phosphoundecaprenol. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides (By similarity)
E5E96_12320	ENOG4108I2E	Bifunctional enzyme that catalyzes the oxidative decarboxylation of UDP-glucuronic acid (UDP-GlcUA) to UDP-4-keto- arabinose (UDP-Ara4O) and the addition of a formyl group to UDP-4- amino-4-deoxy-L-arabinose (UDP-L-Ara4N) to form UDP-L-4-formamido- arabinose (UDP-L-Ara4FN). The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides (By similarity)
E5E96_12325	ENOG4105CKK	Glycosyl transferase, family 2
E5E96_12330	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
E5E96_12335	ENOG4105C6Y	Udp-glucose 6-dehydrogenase
E5E96_12340	ENOG4105YP7	UPF0270 protein
E5E96_12350	ENOG4105DNZ	Alpha Beta Hydrolase
E5E96_12365	ENOG4105VKU	nucleicacid-binding protein
E5E96_12370	ENOG4108YZY	peptidylprolyl cis-trans isomerase
E5E96_12385	ENOG4108V1T	peptidylprolyl cis-trans isomerase
E5E96_12390	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
E5E96_12410	ENOG4105CGH	5'-nucleotidase
E5E96_12415	ENOG4105BZU	Histidine kinase
E5E96_12430	ENOG4105CDU	Replicative dna helicase
E5E96_12435	ENOG4105CDU	Replicative dna helicase
E5E96_12440	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
E5E96_12450	ENOG4105K5D	4fe-4S ferredoxin iroN-sulfur binding
E5E96_12455	ENOG4105CFP	Peptidase U32
E5E96_12460	ENOG4108NJZ	Sensory box GGDEF EAL domain protein
E5E96_12485	ENOG4105C9B	Cysteine desulfurase
E5E96_12490	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
E5E96_12495	ENOG4108Z4W	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis (By similarity)
E5E96_12500	ENOG4105BZU	Histidine kinase
E5E96_12505	ENOG4105C8Q	Methyl-accepting chemotaxis
E5E96_12510	ENOG4108V3W	Chemotaxis protein, CheW
E5E96_12520	ENOG4105CBS	Chea signal transduction histidine kinase
E5E96_12530	ENOG4108VYJ	response regulator receiver protein
E5E96_12535	ENOG4105C8Q	Methyl-accepting chemotaxis
E5E96_12540	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
E5E96_12550	ENOG4105N14	lysine exporter protein LysE YggA
E5E96_12555	ENOG4105CFP	Peptidase U32
E5E96_12585	ENOG4105CTD	carboxy-peptidase
E5E96_12610	ENOG4105E1F	short-chain dehydrogenase reductase
E5E96_12615	ENOG4105J5J	Outer membrane porin
E5E96_12620	ENOG4105C8Q	Methyl-accepting chemotaxis
E5E96_12630	ENOG4105C9J	Catalyzes the reversible cleavage of L-rhamnulose-1- phosphate to dihydroxyacetone phosphate (DHAP) and L-lactaldehyde (By similarity)
E5E96_12635	ENOG4105C0A	alcohol dehydrogenase
E5E96_12640	ENOG4107S4Z	Activates expression of the rhaBAD and rhaT operons (By similarity)
E5E96_12650	ENOG4105DKG	l-rhamnose isomerase
E5E96_12655	ENOG4107YRA	Uptake of L-rhamnose across the boundary membrane with the concomitant transport of protons into the cell (symport system) (By similarity)
E5E96_12660	ENOG4105M10	Involved in the anomeric conversion of L-rhamnose (By similarity)
E5E96_12710	ENOG4105W5Q	DNA repair protein (RadC
E5E96_12755	ENOG4108NF7	phage-type endonuclease
E5E96_12785	ENOG4105CQC	Prephenate dehydratase
E5E96_12815	ENOG4107SEY	Conserved Protein
E5E96_12820	ENOG4108XDN	Transcriptional regulator
E5E96_12825	ENOG4105CVP	deoxyribo-dipyrimidine photolyase
E5E96_12835	ENOG4105EMU	Dehydrogenase
E5E96_12850	ENOG4105CV9	cyclopropane-fatty-acyl-phospholipid synthase
E5E96_12875	ENOG4108RMU	ferritin dps family protein
E5E96_12880	ENOG4105EJ7	Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O (By similarity)
E5E96_12890	ENOG4105CMR	udp-glucose 4-epimerase
E5E96_12895	ENOG4105DRC	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity)
E5E96_13035	ENOG4105JXR	Protein of unknown function (DUF3296)
E5E96_13050	ENOG410679B	prophage CP4-57 regulatory protein alpA
E5E96_13065	ENOG4108WC9	type VI secretion system effector, hcp1 family
E5E96_13070	ENOG4105CS6	Rhs element vgr protein
E5E96_13110	ENOG4105VJY	transcriptional regulator
E5E96_13115	ENOG4108WC9	type VI secretion system effector, hcp1 family
E5E96_13165	ENOG4105C7K	acetolactate synthase
E5E96_13170	ENOG4107S0N	DJ-1 family
E5E96_13175	ENOG4108JZF	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity)
E5E96_13180	ENOG4108VPT	UPF0234 protein
E5E96_13190	ENOG4105EYM	Major Facilitator superfamily
E5E96_13200	ENOG4108R5K	PPIases accelerate the folding of proteins (By similarity)
E5E96_13210	ENOG4105D8J	Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle (By similarity)
E5E96_13215	ENOG4105M85	Bola protein
E5E96_13220	ENOG4105DWQ	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
E5E96_13225	ENOG4108J5C	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
E5E96_13230	ENOG4106I92	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
E5E96_13235	ENOG4105F5D	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
E5E96_13240	ENOG4108IUB	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
E5E96_13245	ENOG4105D26	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. The first step is catalyzed by NqrF, which accepts electrons from NADH and reduces ubiquinone-1 to ubisemiquinone by a one-electron transfer pathway (By similarity)
E5E96_13250	ENOG4105CJ2	(LipO)protein
E5E96_13265	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
E5E96_13270	ENOG4105C8Q	Methyl-accepting chemotaxis
E5E96_13275	ENOG4105ETT	transcriptional Regulator, LysR family
E5E96_13285	ENOG4105M08	Membrane
E5E96_13290	ENOG4105EZ6	Catalyzes the 2'-O-methylation at nucleotide C2498 in 23S rRNA (By similarity)
E5E96_13300	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
E5E96_13305	ENOG4105CIQ	May have a role in processing of nucleic acids. It is probably not an exonuclease
E5E96_13310	ENOG4105EWT	decarboxylase family
E5E96_13315	ENOG4105BZU	Histidine kinase
E5E96_13325	ENOG4107R1K	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) (By similarity)
E5E96_13330	ENOG4108T6E	Interacts with the SecY protein in vivo. May bind preferentially to an uncomplexed state of SecY, thus functioning either as a chelating agent for excess SecY in the cell or as a regulatory factor that negatively controls the translocase function (By similarity)
E5E96_13335	ENOG4105EXF	Zn-ribbon-containing, possibly nucleic-acid-binding protein
E5E96_13360	ENOG4105WP7	tRNA pseudouridine synthase C
E5E96_13365	ENOG4105DR9	pseudouridine synthase
E5E96_13370	ENOG4105QDK	Flavodoxin
E5E96_13375	ENOG4108KDD	Involved in the transport of maltose and maltodextrins (By similarity)
E5E96_13380	ENOG4107W52	maltose operon periplasmic protein
E5E96_13385	ENOG4105CI1	PTS System
E5E96_13390	ENOG4108T8E	UPF0325 protein
E5E96_13395	ENOG4105DMJ	Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate (By similarity)
E5E96_13400	ENOG4105E1P	Modifies, by uridylylation or deuridylylation the PII (GlnB) regulatory protein (By similarity)
E5E96_13405	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
E5E96_13410	ENOG4105CE9	30S ribosomal protein S2
E5E96_13415	ENOG4105CU7	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity)
E5E96_13420	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
E5E96_13425	ENOG4108VCV	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity)
E5E96_13435	ENOG4105KNE	Phosphatidate cytidylyltransferase
E5E96_13440	ENOG4105CEA	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity)
E5E96_13445	ENOG4105DZP	Membrane-associated zinc metalloprotease
E5E96_13455	ENOG4108RFI	Molecular chaperone that interacts specifically with outer membrane proteins, thus maintaining the solubility of early folding intermediates during passage through the periplasm (By similarity)
E5E96_13460	ENOG4105D7M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
E5E96_13465	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
E5E96_13470	ENOG4105DAF	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
E5E96_13475	ENOG4105D0V	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
E5E96_13480	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
E5E96_13485	ENOG4105C0B	DNA polymerase III (alpha subunit)
E5E96_13490	ENOG4107QM9	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA (By similarity)
E5E96_13495	ENOG4108M3R	transcriptional activator CadC
E5E96_13500	ENOG4105D5Q	Arginine ornithine antiporter
E5E96_13505	ENOG4105CXN	decarboxylase
E5E96_13510	ENOG4107XGF	functions in a salvage pathway. Uses pyridoxamine (By similarity)
E5E96_13520	ENOG4105EQ2	LysR family Transcriptional regulator
E5E96_13525	ENOG4105C44	Serine transporter
E5E96_13535	ENOG4107XDQ	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity)
E5E96_13540	ENOG4105EXG	Transcriptional regulator
E5E96_13545	ENOG4105ENX	hydrolase
E5E96_13550	ENOG4105ENX	hydrolase
E5E96_13555	ENOG4105EQ2	LysR family Transcriptional regulator
E5E96_13560	ENOG4105DVH	amino acid
E5E96_13570	ENOG4105C5H	ABC transporter
E5E96_13580	ENOG4105C9K	Endothelin-converting enzyme 1
E5E96_13585	ENOG4105D3U	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
E5E96_13590	ENOG4105BZU	Histidine kinase
E5E96_13625	ENOG4107T9C	Alpha amylase catalytic region
E5E96_13655	ENOG4105DIT	ErfK YbiS YcfS YnhG family protein
E5E96_13660	ENOG4105EAQ	(twin-arginine translocation) pathway signal
E5E96_13670	ENOG4105EN6	Membrane
E5E96_13675	ENOG4105EXN	Sulfate transport protein CysZ
E5E96_13690	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
E5E96_13700	ENOG4105CJD	(Anaerobic) ribonucleoside-triphosphate reductase
E5E96_13705	ENOG4108RDD	Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine (By similarity)
E5E96_13735	ENOG4105J12	Multidrug resistance protein mdtN
E5E96_13740	ENOG4108US0	Transcription regulator that can specifically activate or repress expression of target genes (By similarity)
E5E96_13750	ENOG4105D2K	citrate carrier protein
E5E96_13755	ENOG4107R1I	NAD-dependent malic enzyme
E5E96_13760	ENOG4105CEQ	signal transduction histidine kinase regulating citrate malate metabolism
E5E96_13765	ENOG4106YYS	transcriptional regulatory protein
E5E96_13770	ENOG4108IPJ	Membrane
E5E96_13780	ENOG4105C26	Dehydrogenase
E5E96_13785	ENOG4108JU9	GAF modulated sigma54 specific transcriptional regulator Fis family
E5E96_13790	ENOG4105C1G	acyl-Coa dehydrogenase
E5E96_13795	ENOG4105C04	l-carnitine dehydratase bile acid-inducible protein F
E5E96_13800	ENOG4108ZI4	Glyoxalase Bleomycin resistance protein (Dioxygenase
E5E96_13805	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
E5E96_13810	ENOG4105BZU	Histidine kinase
E5E96_13815	ENOG4105DJH	phosphate
E5E96_13820	ENOG4105ERG	peptidase m48, ste24p
E5E96_13835	ENOG4106N3A	copper homeostasis protein cutc
E5E96_13845	ENOG4108V1T	peptidylprolyl cis-trans isomerase
E5E96_13850	ENOG4105CJ1	ABC, transporter
E5E96_13870	ENOG4105PTV	Nudix Hydrolase
E5E96_13895	ENOG4105BZG	amino acid carrier protein
E5E96_13900	ENOG4108KMH	lipoate-protein ligase a
E5E96_13905	ENOG4105C2W	permease
E5E96_13915	ENOG4105RKX	Protein of unknown function (DUF2498)
E5E96_13920	ENOG4105UQX	Mate efflux family protein
E5E96_13925	ENOG4105ECQ	AraC Family Transcriptional Regulator
E5E96_13930	ENOG4107R1I	NAD-dependent malic enzyme
E5E96_13935	ENOG4105UYK	outer membrane protein a
E5E96_13940	ENOG4105UYK	outer membrane protein a
E5E96_13945	ENOG4105UYK	outer membrane protein a
E5E96_13960	ENOG4105C8J	)-transporter
E5E96_13965	ENOG4105D78	K07001 NTE family protein
E5E96_13970	ENOG4105BZU	Histidine kinase
E5E96_13975	ENOG4105J12	Multidrug resistance protein mdtN
E5E96_13980	ENOG4105BZS	acriflavin resistance protein
E5E96_13990	ENOG4105CCT	upf0313 protein
E5E96_14015	ENOG4105EP9	oxidoreductase
E5E96_14025	ENOG4105NHU	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group (By similarity)
E5E96_14030	ENOG4105D8C	Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity)
E5E96_14035	ENOG4105E4C	Lytic transglycosylase catalytic
E5E96_14045	ENOG4108VC8	Peptidase family M23
E5E96_14060	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
E5E96_14070	ENOG4105CIY	formyltetrahydrofolate deformylase
E5E96_14075	ENOG4105C66	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity)
E5E96_14085	ENOG4107QR8	Thioredoxin
E5E96_14090	ENOG4107YAK	holo-(acyl carrier protein) synthase 2
E5E96_14095	ENOG4107TT5	NLP P60 protein
E5E96_14100	ENOG4105EBA	Specifically methylates the adenine in position 1618 of 23S rRNA (By similarity)
E5E96_14115	ENOG4107N1Q	ErfK YbiS YcfS YnhG family protein
E5E96_14140	ENOG4108VPX	Involved in 1,2-propanediol (1,2-PD) degradation by catalyzing the conversion of propanoyl-CoA to propanoyl-phosphate (By similarity)
E5E96_14145	ENOG4105KNY	Microcompartments protein
E5E96_14150	ENOG4105F1A	Pyruvate formate-lyase
E5E96_14155	ENOG4105C6N	Formate acetyltransferase
E5E96_14160	ENOG4105C0A	alcohol dehydrogenase
E5E96_14170	ENOG4105C0A	alcohol dehydrogenase
E5E96_14175	ENOG4105KNY	Microcompartments protein
E5E96_14180	ENOG4105KNY	Microcompartments protein
E5E96_14185	ENOG4105KNY	Microcompartments protein
E5E96_14205	ENOG4105CBN	LysR family transcriptional regulator
E5E96_14210	ENOG4107H9G	Necessary for formate dehydrogenase activity (By similarity)
E5E96_14215	ENOG4107QKC	Oxidoreductase alpha (molybdopterin) subunit
E5E96_14225	ENOG4107SSZ	Phosphatase
E5E96_14235	ENOG4107QPN	acyl-Coa dehydrogenase
E5E96_14240	ENOG4105BZS	acriflavin resistance protein
E5E96_14250	ENOG4105CA9	Pyruvate kinase
E5E96_14255	ENOG4106KNT	transcriptional regulator
E5E96_14270	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
E5E96_14275	ENOG4105CBM	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 (By similarity)
E5E96_14280	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
E5E96_14290	ENOG4105VQ0	flagellar hook-basal body complex protein fliE
E5E96_14295	ENOG4105C1F	The M ring may be actively involved in energy transduction (By similarity)
E5E96_14300	ENOG4105CS3	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
E5E96_14310	ENOG4108JIR	Flagellum-specific ATP synthase
E5E96_14330	ENOG4105D24	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
E5E96_14335	ENOG4105DD5	Flagellar motor switch protein
E5E96_14340	ENOG4105VTB	flagellar biosynthesis protein fliO
E5E96_14345	ENOG4105CN7	Flagellar biosynthetic protein FliP
E5E96_14350	ENOG4105VS8	Flagellar biosynthetic protein fliq
E5E96_14355	ENOG4105D19	Role in flagellar biosynthesis (By similarity)
E5E96_14360	ENOG4105D00	flagellar biosynthetic protein flhB
E5E96_14365	ENOG4105D7B	Flagellar biosynthesis protein flha
E5E96_14370	ENOG4105FZW	flagellar biosynthesis regulator FlhF
E5E96_14380	ENOG4105DN4	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
E5E96_14385	ENOG4108VYJ	response regulator receiver protein
E5E96_14390	ENOG4108KCC	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P) (By similarity)
E5E96_14400	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
E5E96_14405	ENOG4105E14	MotA TolQ exbB proton channel
E5E96_14410	ENOG4108SEK	ompa motb domain protein
E5E96_14415	ENOG4107QJE	Chromosome Partitioning Protein
E5E96_14425	ENOG4108V3W	Chemotaxis protein, CheW
E5E96_14440	ENOG4105CA5	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes (By similarity)
E5E96_14445	ENOG41060IM	Heme exporter protein
E5E96_14450	ENOG4105X3C	heme exporter protein
E5E96_14455	ENOG4108ZKK	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH (By similarity)
E5E96_14460	ENOG4105DA4	cytochrome c-type biogenesis protein
E5E96_14465	ENOG4107QX9	Thiol disulfide interChange protein
E5E96_14470	ENOG4105KWW	Biogenesis protein
E5E96_14475	ENOG4105KWW	Biogenesis protein
E5E96_14480	ENOG410903C	(LipO)protein
E5E96_14485	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
E5E96_14490	ENOG4105M2J	Glutaredoxin
E5E96_14510	ENOG4108S7T	Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) (By similarity)
E5E96_14525	ENOG4108YYD	acetyltransferase
E5E96_14535	ENOG4105EZE	Cupin 4 family protein
E5E96_14540	ENOG4107QTF	adenylosuccinate lyase
E5E96_14545	ENOG41075W9	High frequency lysogenization protein HflD homolog
E5E96_14550	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
E5E96_14560	ENOG4108R99	pseudouridine synthase
E5E96_14570	ENOG4108YRF	PTS System
E5E96_14580	ENOG4105CXY	transporter
E5E96_14595	ENOG4105DM4	PTS System
E5E96_14625	ENOG4108W0I	acetyltransferase
E5E96_14635	ENOG4108Z6Z	Transcriptional regulator
E5E96_14640	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
E5E96_14645	ENOG4107P2S	Transcriptional regulator
E5E96_14650	ENOG4105CI1	PTS System
E5E96_14655	ENOG4105C87	Aminotransferase class I and II
E5E96_14670	ENOG4105DM4	PTS System
E5E96_14685	ENOG4105EIP	mannose-6-phosphate isomerase
E5E96_14690	ENOG4106R3P	AraC family transcriptional regulator
E5E96_14695	ENOG4108HMX	isocitrate dehydrogenase (NADP)
E5E96_14705	ENOG4105BZC	d-serine deaminase
E5E96_14715	ENOG4105W8I	Transcriptional regulator
E5E96_14725	ENOG41090ED	Protein with unknown function (DUF469)
E5E96_14740	ENOG4107SCJ	type I restriction enzyme EcoKI subunit R
E5E96_14745	ENOG4106H3A	restriction
E5E96_14755	ENOG4108UH4	Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity)
E5E96_14760	ENOG4108Z1B	Cyclase dehydrase
E5E96_14765	ENOG4105VDB	UPF0125 protein
E5E96_14770	ENOG4105K4T	epimerase
E5E96_14775	ENOG4105YRI	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
E5E96_14780	ENOG4105C0A	alcohol dehydrogenase
E5E96_14785	ENOG4107SXA	Phosphorylase
E5E96_14790	ENOG4105D3G	Pseudouridine synthase
E5E96_14795	ENOG4105DU0	nucleoside hydrolase
E5E96_14810	ENOG4105RX8	Protein of unknown function (DUF1523)
E5E96_14815	ENOG4108NVR	Methyl-accepting chemotaxis
E5E96_14820	ENOG410829K	Lysine exporter protein (Lyse ygga)
E5E96_14830	ENOG4105C3N	Participates in control of cell volume in low-osmolarity conditions (By similarity)
E5E96_14840	ENOG4105C3N	Participates in control of cell volume in low-osmolarity conditions (By similarity)
E5E96_14855	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
E5E96_14860	ENOG4105KUZ	arsenate reductase
E5E96_14875	ENOG4105CEE	C4-dicarboxylate transporter
E5E96_14890	ENOG4105DS2	Anaerobic c4-dicarboxylate transporter
E5E96_14895	ENOG4105C5S	asparaginyl-tRNA synthetase
E5E96_14915	ENOG4105CZF	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism (By similarity)
E5E96_14920	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
E5E96_14925	ENOG410626R	Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity)
E5E96_14930	ENOG4105E78	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity)
E5E96_14935	ENOG4105D0M	Protease HtpX homolog
E5E96_14940	ENOG4107SDU	Methyl-accepting chemotaxis
E5E96_14945	ENOG4105QVC	MOSC domain-containing protein
E5E96_14945	ENOG4105QVC	MOSC domain-containing protein
E5E96_14975	ENOG4105UQX	Mate efflux family protein
E5E96_15015	ENOG4107Z3H	Transcriptional regulator, TetR family
E5E96_15020	ENOG4107RGH	Aldehyde dehydrogenase
E5E96_15030	ENOG4107TT5	NLP P60 protein
E5E96_15040	ENOG4105C5Q	Transcriptional regulator
E5E96_15045	ENOG4105D3R	alkyl hydroperoxide reductase
E5E96_15065	ENOG4105PFA	Catalyzes the conversion of 5-hydroxyuridine (ho5U) to 5-methoxyuridine (mo5U) at position 34 in tRNA (By similarity)
E5E96_15070	ENOG4105DA6	Catalyzes the conversion of 5-methoxyuridine (mo5U) to uridine-5-oxyacetic acid (cmo5U) at position 34 in tRNA. May also participate in the methylation of uridine-5-oxyacetic acid (cmo5U) to uridine-5-oxyacetic acid methyl ester (mcmo5U) (By similarity)
E5E96_15075	ENOG41081XQ	Conserved Protein
E5E96_15080	ENOG4105C9M	aspartyl-trna synthetase
E5E96_15085	ENOG4105CDY	transcriptional regulatory protein
E5E96_15090	ENOG4105DIJ	Phosphoethanolamine transferase
E5E96_15095	ENOG4105E2R	ROK family
E5E96_15100	ENOG4105CE4	GlcNAc 6-P deacetylase
E5E96_15105	ENOG4105CKA	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion (By similarity)
E5E96_15110	ENOG4105CI1	PTS System
E5E96_15115	ENOG4105E2D	ec 3.2.1.52
E5E96_15125	ENOG4105CX6	glutaminyL-tRNA synthetase
E5E96_15130	ENOG41090R7	Ferric uptake
E5E96_15140	ENOG4105MHQ	Low-potential electron donor to a number of redox enzymes (By similarity)
E5E96_15145	ENOG4105NNH	LexA regulated protein
E5E96_15160	ENOG4107CDU	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated (By similarity)
E5E96_15165	ENOG4107QIX	Phosphoglucomutase (EC 5.4.2.2
E5E96_15190	ENOG4105CVE	Lytic murein transglycosylase
E5E96_15195	ENOG4108T9J	Cdp-alcohol phosphatidyltransferase
E5E96_15200	ENOG4108VGW	abc transporter atp-binding protein
E5E96_15220	ENOG4107ZN8	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity (By similarity)
E5E96_15235	ENOG4105KQ5	peptidylprolyl cis-trans isomerase
E5E96_15245	ENOG4105CFU	surface antigen
E5E96_15250	ENOG4105MA0	exported protein
E5E96_15270	ENOG4108WPH	sigma 54 modulation protein ribosomal protein S30EA
E5E96_15275	ENOG4105BZU	Histidine kinase
E5E96_15280	ENOG4107SC1	transglycosylase
E5E96_15285	ENOG41060NJ	transcriptional regulator
E5E96_15295	ENOG4105NAU	thioesterase Superfamily protein
E5E96_15310	ENOG4105E9H	Lytic Murein transglycosylase
E5E96_15315	ENOG4108RW0	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
E5E96_15320	ENOG4105D1A	Methyltransferase
E5E96_15325	ENOG4108UMW	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
E5E96_15330	ENOG4107RZZ	dna polymerase iii epsilon subunit
E5E96_15340	ENOG4105C9X	ppx gppa phosphatase
E5E96_15345	ENOG4105CUU	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) (By similarity)
E5E96_15350	ENOG4105RH4	Glycine cleavage system transcriptional repressor
E5E96_15365	ENOG4105BZU	Histidine kinase
E5E96_15375	ENOG4107QNR	UPF0135 protein
E5E96_15380	ENOG4108V3E	phosphoribosylglycinamide formyltransferase
E5E96_15385	ENOG4105CXB	phosphoribosylaminoimidazole synthetase
E5E96_15390	ENOG4105CZ5	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate (By similarity)
E5E96_15400	ENOG4108KZ1	Mediates the interaction of DNA replication inititator protein DnaA with DNA polymerase subunit beta sliding clamp (dnaN). Stimulates hydrolysis of ATP-DnaA to ADP-DnaA, rendering DnaA inactive for reinititation, a process called regulatory inhibition of DnaA or RIDA (By similarity)
E5E96_15405	ENOG4108I9X	Isocitrate lyase
E5E96_15410	ENOG4107QP3	malate synthase g
E5E96_15420	ENOG4108Z6B	deaminase
E5E96_15425	ENOG4105C8U	phosphate abc transporter
E5E96_15430	ENOG4105E2Z	phosphate ABC transporter (Permease
E5E96_15435	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
E5E96_15445	ENOG4105C37	(CBS) domain
E5E96_15455	ENOG4105C3R	Methionine synthase
E5E96_15460	ENOG4105D5Q	Arginine ornithine antiporter
E5E96_15480	ENOG4105CDA	abc transporter atp-binding protein
E5E96_15485	ENOG4105E5Q	amino acid AbC transporter
E5E96_15490	ENOG4106TNF	Periplasmic binding protein
E5E96_15500	ENOG4105CXY	transporter
E5E96_15505	ENOG4105BZU	Histidine kinase
E5E96_15510	ENOG4108KX4	response regulator
E5E96_15515	ENOG4105NXH	GreA GreB family elongation factor
E5E96_15540	ENOG4105C9W	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity (By similarity)
E5E96_15545	ENOG4108ISG	Major Facilitator
E5E96_15550	ENOG4105DGU	Histone deacetylase
E5E96_15560	ENOG4105DVT	helicase
E5E96_15575	ENOG4105CGF	Aromatic amino acid aminotransferase
E5E96_15580	ENOG4105D06	uba thif-type nad fad binding protein
E5E96_15585	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
E5E96_15590	ENOG4105EUJ	GTP cyclohydrolase i
E5E96_15595	ENOG4105C8Q	Methyl-accepting chemotaxis
E5E96_15600	ENOG4105CKU	formyltetrahydrofolate synthetase
E5E96_15605	ENOG4105CKU	formyltetrahydrofolate synthetase
E5E96_15615	ENOG4105CC0	LysR family Transcriptional regulator
E5E96_15620	ENOG4108YYC	ycei family
E5E96_15645	ENOG4105D42	Cleaves the N-terminal amino acid of tripeptides (By similarity)
E5E96_15665	ENOG4105DP5	Catalyzes the biosynthesis of agmatine from arginine (By similarity)
E5E96_15680	ENOG4108N3W	hemolysin secretion protein
E5E96_15685	ENOG4105C44	Serine transporter
E5E96_15690	ENOG4105KME	endoribonuclease L-psp
E5E96_15695	ENOG4105CEM	UPF0597 protein
E5E96_15710	ENOG4108R4U	Hnh endonuclease
E5E96_15720	ENOG4105I9P	Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor (By similarity)
E5E96_15730	ENOG4105D82	Glutamate dehydrogenase
E5E96_15740	ENOG4105FE9	pseudouridine synthase
E5E96_15745	ENOG4105DJ2	Major Facilitator Superfamily
E5E96_15760	ENOG4105D2S	major facilitator superfamily
E5E96_15770	ENOG4106428	Protein of unknown function (DUF2496)
E5E96_15790	ENOG4108Q2J	Inner membrane protein YebE
E5E96_15795	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
E5E96_15800	ENOG4105C4M	(Ubiquinol oxidase) subunit I
E5E96_15805	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
E5E96_15815	ENOG4105F27	Major Facilitator
E5E96_15820	ENOG4105CV8	reductase
E5E96_15845	ENOG4105HEI	LysR family (Transcriptional regulator
E5E96_15850	ENOG4108JQ0	Key enzyme in the regulation of glycerol uptake and metabolism (By similarity)
E5E96_15855	ENOG4105D8C	Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity)
E5E96_15860	ENOG4105CXY	transporter
E5E96_15865	ENOG4105E98	transcriptional regulator DeoR family
E5E96_15875	ENOG4105C6V	Glycerol-3-phosphate dehydrogenase
E5E96_15880	ENOG4106MZZ	glycerophosphoryl diester phosphodiesterase
E5E96_15885	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
E5E96_15895	ENOG4105CVI	Transcriptional regulator
E5E96_15900	ENOG4108WFC	UPF0438 protein yifE
E5E96_15905	ENOG4108QSZ	General inhibitor of pancreatic serine proteases inhibits chymotrypsin, trypsin, elastases, factor X, kallikrein as well as a variety of other proteases (By similarity)
E5E96_15925	ENOG4105CUG	Oligopeptidase b
E5E96_15930	ENOG4105D05	Receptor
E5E96_15935	ENOG4105E68	Sulfatase
E5E96_15940	ENOG4105PAN	UPF0352 protein
E5E96_15945	ENOG4106V8H	Nucleoid-associated protein
E5E96_15950	ENOG4107FKK	extracellular solute-binding protein family 1
E5E96_15955	ENOG4105D56	permease protein
E5E96_15965	ENOG4108IJ9	(ABC) transporter
E5E96_15970	ENOG4105CSR	polyphosphate kinase 2
E5E96_15990	ENOG41082K8	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Interacts with IscS and stimulates its activity. Then, accepts a sulfur from IscS and transfers it in turn to TusD (By similarity)
E5E96_15995	ENOG4105ERG	peptidase m48, ste24p
E5E96_16005	ENOG4105K89	arsenate reductase
E5E96_16020	ENOG4108ZYK	Acyl carrier protein phosphodiesterase
E5E96_16025	ENOG4105DYB	Isoaspartyl dipeptidase
E5E96_16030	ENOG4105DWU	Membrane
E5E96_16035	ENOG4108JEH	abc transporter atp-binding protein
E5E96_16040	ENOG4106PMH	Extracellular solute-binding protein family 3
E5E96_16045	ENOG4105DSP	amino acid AbC transporter
E5E96_16060	ENOG4105F1A	Pyruvate formate-lyase
E5E96_16065	ENOG4105BZU	Histidine kinase
E5E96_16070	ENOG4107QMW	pyridine nucleotide-disulfide oxidoreductase
E5E96_16080	ENOG4108JQB	penicillin-binding protein 1C
E5E96_16090	ENOG4105D8I	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS (By similarity)
E5E96_16100	ENOG4105EN6	Membrane
E5E96_16110	ENOG4105I03	Flagellin
E5E96_16115	ENOG4105I03	Flagellin
E5E96_16130	ENOG4105MQ3	flagellar protein FliS
E5E96_16155	ENOG4105DUF	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively (By similarity)
E5E96_16175	ENOG4105ECY	inositol monophosphatase
E5E96_16185	ENOG4105CYM	Glutathione S-transferase
E5E96_16190	ENOG4105E5M	Multidrug resistance protein D
E5E96_16200	ENOG4107YUN	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division (By similarity)
E5E96_16210	ENOG4105D0A	hydroxylase
E5E96_16215	ENOG4105EAK	ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family
E5E96_16220	ENOG4105D43	The glycine cleavage system catalyzes the degradation of glycine (By similarity)
E5E96_16225	ENOG4105KE9	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity)
E5E96_16230	ENOG4105CBI	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
E5E96_16260	ENOG4105D6J	arsenicaL-resistance protein
E5E96_16265	ENOG4105K89	arsenate reductase
E5E96_16290	ENOG4105D3R	alkyl hydroperoxide reductase
E5E96_16295	ENOG4105W87	Cbs domain
E5E96_16300	ENOG4105E2N	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) (By similarity)
E5E96_16305	ENOG4105C6U	Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity)
E5E96_16310	ENOG4105VIE	preprotein translocase, subunit YajC
E5E96_16315	ENOG4107QN8	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
E5E96_16320	ENOG4107RAB	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
E5E96_16365	ENOG4105C3J	Cysteine desulfurase
E5E96_16370	ENOG4107XTC	May be involved in the formation or repair of Fe-S clusters present in iron-sulfur proteins
E5E96_16375	ENOG4108Z4V	iron-sulfur cluster assembly
E5E96_16380	ENOG4108SWN	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA (By similarity)
E5E96_16385	ENOG4105C9I	Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB
E5E96_16390	ENOG4108ZIT	Ferredoxin, 2FE-2S
E5E96_16405	ENOG4108UGX	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity)
E5E96_16410	ENOG4105C55	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
E5E96_16420	ENOG4105HSZ	Cytoskeletal protein that is involved in cell-shape control through regulation of the length of the long axis (By similarity)
E5E96_16425	ENOG4105C4E	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (By similarity)
E5E96_16430	ENOG4105CUT	histidyl-tRNA synthetase
E5E96_16435	ENOG4105N21	Membrane
E5E96_16440	ENOG4105CNE	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
E5E96_16445	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
E5E96_16450	ENOG4105VPD	cellular component movement
E5E96_16460	ENOG4105CHQ	Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella (By similarity)
E5E96_16465	ENOG4107QIK	phosphoribosylformylglycinamidine synthase
E5E96_16470	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
E5E96_16475	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
E5E96_16485	ENOG4105CNR	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
E5E96_16490	ENOG4105C8S	subunit m
E5E96_16495	ENOG4105D65	subunit l
E5E96_16500	ENOG41080EA	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
E5E96_16505	ENOG4107UFS	subunit j
E5E96_16510	ENOG4105P3U	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
E5E96_16515	ENOG4105CMZ	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone (By similarity)
E5E96_16520	ENOG4108IEH	NADH dehydrogenase subunit g
E5E96_16525	ENOG4107QIZ	NADH dehydrogenase
E5E96_16530	ENOG4105GKE	subunit e
E5E96_16535	ENOG4105CQV	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
E5E96_16540	ENOG4105ES3	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
E5E96_16545	ENOG4105KWU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
E5E96_16550	ENOG4105ER2	Ompa motb domain protein
E5E96_16555	ENOG4105E14	MotA TolQ exbB proton channel
E5E96_16570	ENOG4105HA9	of methanol dehydrogenase type
E5E96_16580	ENOG4105HPZ	Involved in the removal of murein from the sacculus. May also facilitate integration of nascent murein strands into the sacculus by cleaving the peptide bonds between neighboring strands in mature murein (By similarity)
E5E96_16590	ENOG4105VFU	Rna-binding protein
E5E96_16595	ENOG4107RGM	aldo keto reductase
E5E96_16620	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
E5E96_16625	ENOG4105CBN	LysR family transcriptional regulator
E5E96_16635	ENOG4105BZU	Histidine kinase
E5E96_16640	ENOG4108DBC	nitroreductase
E5E96_16655	ENOG4105D2S	major facilitator superfamily
E5E96_16660	ENOG4105CMU	LysR family (Transcriptional regulator
E5E96_16665	ENOG4107R11	Transcriptional regulator
E5E96_16670	ENOG4108JEN	Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate (By similarity)
E5E96_16675	ENOG4105CAT	Cytidine monophosphate kinase
E5E96_16680	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
E5E96_16685	ENOG41080YA	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
E5E96_16695	ENOG4105CFV	Tetratricopeptide repeat protein
E5E96_16700	ENOG4106EG9	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) (By similarity)
E5E96_16715	ENOG4105FD2	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) (By similarity)
E5E96_16720	ENOG4105EIZ	Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity)
E5E96_16725	ENOG4105VRT	cytoplasmic protein
E5E96_16730	ENOG4108WBT	adenosyltransferase
E5E96_16740	ENOG4107S6Z	Na H antiporter
E5E96_16745	ENOG4107104	thymidine kinase
E5E96_16755	ENOG4108RMJ	sensory transduction regulator
E5E96_16770	ENOG4108WC9	type VI secretion system effector, hcp1 family
E5E96_16775	ENOG4105CS6	Rhs element vgr protein
E5E96_16785	ENOG4105CNA	YD repeat protein
E5E96_16845	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
E5E96_16880	ENOG4105CS6	Rhs element vgr protein
E5E96_16965	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
E5E96_16970	ENOG4105VEQ	Cold shock protein
E5E96_16975	ENOG4105KAE	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation (By similarity)
E5E96_16985	ENOG4105K9U	however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity)
E5E96_16990	ENOG4105DWA	May conjugate Arg from its aminoacyl-tRNA to the N- termini of proteins containing an N-terminal aspartate or glutamate
E5E96_16995	ENOG4108R4Z	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine (By similarity)
E5E96_17000	ENOG4107MBR	17 kDa surface antigen
E5E96_17005	ENOG4105BZU	Histidine kinase
E5E96_17010	ENOG4105C3M	thioredoxin reductase
E5E96_17015	ENOG4105DCF	alanine dehydrogenase
E5E96_17020	ENOG4105EW9	transcriptional regulator AsnC family
E5E96_17025	ENOG4105CNU	cell division protein FtsK
E5E96_17030	ENOG4107Y7W	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) (By similarity)
E5E96_17035	ENOG4105D1H	recombination factor protein RarA
E5E96_17040	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
E5E96_17045	ENOG4105E96	Colicin v production protein
E5E96_17050	ENOG4105CBA	glutamine phosphoribosylpyrophosphate amidotransferase
E5E96_17055	ENOG4105FR9	TRNA-(Ms 2 io 6 A)-hydroxylase
E5E96_17060	ENOG4108JQ2	peptide transport system atp-binding protein
E5E96_17065	ENOG4108JQ3	Peptide ABC transporter ATP-binding protein
E5E96_17070	ENOG4108EU3	peptide transport system, permease
E5E96_17075	ENOG4108I5W	peptide transport system, permease protein
E5E96_17080	ENOG4108J59	Extracellular solute-binding protein, family 5
E5E96_17085	ENOG4105E51	psp operon transcriptional activator
E5E96_17090	ENOG41087YS	Phage shock protein A
E5E96_17095	ENOG4105YYT	phage shock protein B
E5E96_17105	ENOG4105CM6	amino acid regulated cytosolic protein
E5E96_17110	ENOG4106K28	UPF0283 membrane protein
E5E96_17115	ENOG4105MIR	Phenylalanine 4-monooxygenase
E5E96_17120	ENOG41090A4	Pterin carbinolamine dehydratase
E5E96_17135	ENOG4108WS1	
E5E96_17140	ENOG4108KHX	Diguanylate cyclase
E5E96_17145	ENOG41090EK	ompa motb domain protein
E5E96_17150	ENOG4105EE5	Membrane protein terC
E5E96_17160	ENOG4105MH2	YfcL protein
E5E96_17165	ENOG4108IQE	Amp-dependent synthetase and ligase
E5E96_17170	ENOG4107T42	This enzyme scavenge exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis (By similarity)
E5E96_17175	ENOG41067MG	lrgb family
E5E96_17185	ENOG4107R49	K07407 alpha-galactosidase EC 3.2.1.22
E5E96_17195	ENOG4105CJB	Exodeoxyribonuclease I
E5E96_17200	ENOG4105CAC	Catalyzes the conversion of L-arabinose to L-ribulose (By similarity)
E5E96_17210	ENOG4105EF1	ribulokinase
E5E96_17215	ENOG4105DMK	Periplasmic binding protein LacI transcriptional regulator
E5E96_17225	ENOG4105CNN	ABC, transporter
E5E96_17235	ENOG4105HEI	LysR family (Transcriptional regulator
E5E96_17240	ENOG4105EUB	pirin domain protein
E5E96_17245	ENOG4105YK5	50S ribosomal protein L36
E5E96_17250	ENOG4105NRA	50s ribosomal protein l31 type b
E5E96_17265	ENOG4108VKG	metal-dependent hydrolase
E5E96_17280	ENOG4105CEE	C4-dicarboxylate transporter
E5E96_17290	ENOG4105CWG	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34 (By similarity)
E5E96_17295	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
E5E96_17310	ENOG4105BZN	citrate synthase
E5E96_17315	ENOG4108UTY	succinate dehydrogenase, cytochrome b556 subunit
E5E96_17320	ENOG4105N1I	succinate dehydrogenase, hydrophobic membrane anchor protein
E5E96_17325	ENOG4105C00	Succinate dehydrogenase (Flavoprotein subunit)
E5E96_17330	ENOG4105E33	succinate dehydrogenase
E5E96_17335	ENOG4105C7P	2-oxoglutarate dehydrogenase, E1
E5E96_17340	ENOG4105C7S	Dehydrogenase
E5E96_17345	ENOG4105CMV	Succinyl-CoA synthetase subunit beta
E5E96_17350	ENOG4105CH8	Succinyl-CoA ligase ADP-forming subunit alpha
E5E96_17365	ENOG4105CJP	fad dependent oxidoreductase
E5E96_17370	ENOG4107RCV	ABC transporter, permease
E5E96_17380	ENOG4105C4Y	ABC transporter
E5E96_17390	ENOG4107STF	Involved in phosphonate degradation (By similarity)
E5E96_17395	ENOG4108JPW	Aminotransferase
E5E96_17400	ENOG4108KAZ	Involved in phosphonate degradation (By similarity)
E5E96_17405	ENOG4105C6N	Formate acetyltransferase
E5E96_17410	ENOG4105TMB	Formate nitrite transporter
E5E96_17415	ENOG4105DDY	UPF0142 protein ycaO
E5E96_17425	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
E5E96_17445	ENOG4108RYK	Nad-dependent epimerase dehydratase
E5E96_17450	ENOG4105CR8	Transcriptional regulator
E5E96_17460	ENOG4108XW0	May be a transcriptional activator of genes involved in the multiple antibiotic resistance (Mar) phenotype. It can also activate genes such as sodA, zwf and micF
E5E96_17465	ENOG4105E0K	tonB-dependent siderophore receptor
E5E96_17475	ENOG4105DZ2	Transcriptional regulator
E5E96_17480	ENOG4105DSS	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation (By similarity)
E5E96_17490	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
E5E96_17520	ENOG4105MWK	D-amino acid dehydrogenase, small subunit
E5E96_17535	ENOG4105C0F	tryptophanase EC 4.1.99.1
E5E96_17540	ENOG41061WM	D-Alanyl-D-Alanine
E5E96_17545	ENOG4108Z4K	mutator MutT protein
E5E96_17550	ENOG4108DMF	Cytochrome C biogenesis protein
E5E96_17555	ENOG4107QX9	Thiol disulfide interChange protein
E5E96_17560	ENOG4105DA4	cytochrome c-type biogenesis protein
E5E96_17565	ENOG4105DVI	reductase, NrfD
E5E96_17570	ENOG4105D3S	4Fe-4S Ferredoxin, iron-sulfur binding domain protein
E5E96_17575	ENOG4105JJ8	Cytochrome c nitrite reductase, pentaheme subunit
E5E96_17585	ENOG4105CHG	glycolate oxidase (iron-sulfur subunit)
E5E96_17590	ENOG4108KJ0	anaerobic glycerol-3-phosphate dehydrogenase, subunit B
E5E96_17595	ENOG4107R5Y	anaerobic glycerol-3-phosphate dehydrogenase, subunit A
E5E96_17600	ENOG4105K5B	UPF0225 protein
E5E96_17605	ENOG4105C8Q	Methyl-accepting chemotaxis
E5E96_17610	ENOG4105E2R	ROK family
E5E96_17620	ENOG4106YYS	transcriptional regulatory protein
E5E96_17645	ENOG4105D0C	transport protein
E5E96_17660	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
E5E96_17670	ENOG4105DQR	SNARE associated Golgi
E5E96_17675	ENOG410635M	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein (By similarity)
E5E96_17680	ENOG4105DKR	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity)
E5E96_17685	ENOG4105C05	Multifunctional regulator of fatty acid metabolism (By similarity)
E5E96_17690	ENOG4105ED1	spovr family
E5E96_17700	ENOG4105CYN	Serine protein kinase
E5E96_17705	ENOG4105C9U	ATP-dependent DNA helicase RecQ
E5E96_17710	ENOG4107QV7	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system) (By similarity)
E5E96_17715	ENOG4105C44	Serine transporter
E5E96_17750	ENOG4107QQN	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties (By similarity)
E5E96_17755	ENOG4105C8P	)-transporter
E5E96_17760	ENOG4105K63	Thioredoxin
E5E96_17765	ENOG4105BZU	Histidine kinase
E5E96_17780	ENOG4105BZ1	(ABC) transporter
E5E96_17795	ENOG4105WQ3	Rna-binding protein
E5E96_17805	ENOG4105D1N	poly(r)-hydroxyalkanoic acid synthase, class
E5E96_17830	ENOG4107XGF	functions in a salvage pathway. Uses pyridoxamine (By similarity)
E5E96_17835	ENOG41061CK	Antibiotic biosynthesis monooxygenase
E5E96_17865	ENOG4105KK4	UPF0060 membrane protein
E5E96_17875	ENOG4105K5X	acetyltransferase
E5E96_17880	ENOG4105C1J	atp-dependent rna helicase
E5E96_17885	ENOG4108V06	Glutathione peroxidase
E5E96_17900	ENOG4105CPF	Cell wall formation (By similarity)
E5E96_17910	ENOG4106IUH	DTW domain containing protein
E5E96_17920	ENOG4105VP0	transcriptional regulator, lysR family
E5E96_17935	ENOG4105CPB	ATP-dependent endonuclease of the OLD family
E5E96_17990	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
E5E96_18000	ENOG4105CH2	amidohydrolase
E5E96_18005	ENOG4105CTQ	phosphohexokinase
E5E96_18015	ENOG4107S90	membrAne
E5E96_18020	ENOG4106371	Methyltransferase
E5E96_18025	ENOG4105GHU	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid partitioning. Probably acts via its interaction with MukB and MukE. Overexpression results in anucleate cells. It has a calcium binding activity (By similarity)
E5E96_18030	ENOG4105DAH	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF (By similarity)
E5E96_18035	ENOG4105DUC	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division (By similarity)
E5E96_18055	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
E5E96_18105	ENOG4108Z8G	Alkylphosphonate utilization operon protein PhnA
E5E96_18130	ENOG4105DKJ	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
E5E96_18135	ENOG4105BZU	Histidine kinase
E5E96_18145	ENOG4108DG9	Smr protein MutS2
E5E96_18150	ENOG4105C76	Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue (By similarity)
E5E96_18155	ENOG4105D10	5-enolpyruvylshikimate-3-phosphate phospholyase
E5E96_18165	ENOG4105C1J	atp-dependent rna helicase
E5E96_18180	ENOG4105E0U	tyrosine-specific transport protein
E5E96_18185	ENOG4107B7Y	DNA-binding transcriptional regulator FruR
E5E96_18190	ENOG4105DTZ	bifunctional PTS system fructose-specific transporter subunit IIA HPr protein
E5E96_18195	ENOG4105DE4	1-phosphofructokinase
E5E96_18200	ENOG4105DM4	PTS System
E5E96_18205	ENOG4108Y83	glucose-6-phosphate isomerase
E5E96_18210	ENOG4107P2S	Transcriptional regulator
E5E96_18225	ENOG4105DAS	pts system
E5E96_18230	ENOG4105ETZ	PTS System
E5E96_18235	ENOG4105F3R	pts system mannose fructose sorbose family iid
E5E96_18240	ENOG4107SZR	mannose-6-phosphate isomerase
E5E96_18245	ENOG4105XZD	Fe-S protein
E5E96_18250	ENOG4105CA3	membrane-bound lytic murein transglycosylase
E5E96_18255	ENOG4105XPH	Ferredoxin
E5E96_18260	ENOG4105E05	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
E5E96_18265	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
E5E96_18270	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
E5E96_18275	ENOG4108HWB	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
E5E96_18280	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
E5E96_18295	ENOG4105C22	threonyL-tRNA synthetase
E5E96_18300	ENOG4108UUX	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity)
E5E96_18305	ENOG41083UC	50s ribosomal protein L35
E5E96_18310	ENOG4108YZX	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity)
E5E96_18315	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
E5E96_18320	ENOG4105C6A	phenylalanyl-tRNA synthetase (beta subunit)
E5E96_18325	ENOG4108ZUF	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
E5E96_18330	ENOG4105BZU	Histidine kinase
E5E96_18355	ENOG4108KHX	Diguanylate cyclase
E5E96_18360	ENOG4105ETE	Transcriptional regulator (LacI family
E5E96_18365	ENOG4108RVA	ribokinase
E5E96_18370	ENOG4105E9V	Periplasmic binding protein LacI transcriptional regulator
E5E96_18375	ENOG4105CNN	ABC, transporter
E5E96_18380	ENOG4105C2J	ABC transporter
E5E96_18385	ENOG4105MRB	Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose (By similarity)
E5E96_18390	ENOG4108RXX	maleylacetoacetate isomerase
E5E96_18405	ENOG4105CB3	Required for the thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32) (By similarity)
E5E96_18410	ENOG4105Q9Y	Universal stress protein
E5E96_18415	ENOG4105DS0	Transcriptional regulator, Crp Fnr family
E5E96_18440	ENOG4105D6P	C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex (By similarity)
E5E96_18455	ENOG4105EUH	cytochrome C oxidase, cbb3-type, subunit i
E5E96_18465	ENOG4108ZGC	gaf domain protein
E5E96_18470	ENOG41073DY	may be a structural element that influences the osmotic activation of ProP at a post-translational level (By similarity)
E5E96_18475	ENOG4105CN1	protease
E5E96_18480	ENOG4105CD8	aminopeptidase N
E5E96_18490	ENOG4105C7I	Dehydrogenase
E5E96_18495	ENOG4107QYT	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor (By similarity)
E5E96_18500	ENOG4108T7E	Contributes to the efficiency of the cell division process by stabilizing the polymeric form of the cell division protein FtsZ. Acts by promoting interactions between FtsZ protofilaments and suppressing the GTPase activity of FtsZ (By similarity)
E5E96_18515	ENOG4105C5H	ABC transporter
E5E96_18525	ENOG4105WFT	During stationary phase, converts 70S ribosomes to an inactive dimeric form (100S ribosomes) (By similarity)
E5E96_18530	ENOG4108RKI	Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl- ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)- decenoyl-ACP. Can catalyze the dehydratase reaction for beta- hydroxyacyl-ACPs with saturated chain lengths up to 16 0, being most active on intermediate chain length (By similarity)
E5E96_18535	ENOG4105DAN	ATP-dependent protease
E5E96_18575	ENOG4105MQ5	zona occludens toxin
E5E96_18595	ENOG4105X2V	dna damage-inducible protein
E5E96_18605	ENOG4105PDP	Short chain dehydrogenase
E5E96_18645	ENOG4105DXD	2-methylcitrate dehydratase
E5E96_18650	ENOG4105BZN	citrate synthase
E5E96_18655	ENOG4105CR4	methylisocitrate lyase
E5E96_18665	ENOG4105F1S	paraquat-inducible protein a
E5E96_18670	ENOG4105DY2	Paraquat-inducible protein b
E5E96_18675	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
E5E96_18715	ENOG4105F8V	Hydrolase, tatD family
E5E96_18720	ENOG4107QRG	dna polymerase iii
E5E96_18725	ENOG4108ZMD	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity)
E5E96_18730	ENOG4105HHA	aminodeoxychorismate lyase
E5E96_18735	ENOG4105YAZ	4-amino-4-deoxychorismate lyase
E5E96_18740	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
E5E96_18745	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
E5E96_18750	ENOG4105CHR	reductase
E5E96_18755	ENOG4105CJF	Malonyl coA-acyl carrier protein transacylase
E5E96_18760	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
E5E96_18765	ENOG4105C6B	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA (By similarity)
E5E96_18770	ENOG4105VGS	50s ribosomal protein l32
E5E96_18775	ENOG4105FCQ	metal-binding, possibly nucleic acid-binding protein
E5E96_18785	ENOG4105G2Y	Transcriptional regulator
E5E96_18790	ENOG4105CNH	Multidrug resistance protein MdtL
E5E96_18795	ENOG4108UHJ	MAF-like protein
E5E96_18800	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
E5E96_18805	ENOG4105EI2	Pseudouridine synthase
E5E96_18810	ENOG4105C03	ribonuclease
E5E96_18815	ENOG4105CJ3	phosphate transporter
E5E96_18825	ENOG4105DHP	deoxycytidine triphosphate deaminase
E5E96_18830	ENOG4105DBI	uridine monophosphokinase
E5E96_18835	ENOG4105D1F	ATP-binding protein
E5E96_18840	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
E5E96_18845	ENOG4108K3A	Glutathione S-transferase
E5E96_18850	ENOG4105VSY	K01512 acylphosphatase EC 3.6.1.7
E5E96_18855	ENOG4108N3W	hemolysin secretion protein
E5E96_18860	ENOG4105DR4	Methyltransferase
E5E96_18870	ENOG4105FAT	Acyl-transferase
E5E96_18875	ENOG4105D4F	Synthesizes selenophosphate from selenide and ATP (By similarity)
E5E96_18880	ENOG4105CR7	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA (By similarity)
E5E96_18885	ENOG4105C5X	domain protein
E5E96_18890	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
E5E96_18900	ENOG4105KW6	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance (By similarity)
E5E96_18910	ENOG4105CQ7	ATP-dependent helicase
E5E96_18935	ENOG4105KDX	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection (By similarity)
E5E96_18940	ENOG4107QMP	dna polymerase iii subunits gamma and tau
E5E96_18945	ENOG4109003	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity)
E5E96_18950	ENOG4105WD1	Membrane
E5E96_18955	ENOG4105FBT	Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs (By similarity)
E5E96_18970	ENOG4105ZIE	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides (By similarity)
E5E96_18975	ENOG4105CEY	Amp-dependent synthetase and ligase
E5E96_18980	ENOG410626R	Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity)
E5E96_18990	ENOG41072GX	Peptidase M22 Glycoprotease
E5E96_19000	ENOG4105DVT	helicase
E5E96_19010	ENOG4105E21	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity)
E5E96_19015	ENOG4105CEK	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity)
E5E96_19020	ENOG4105CIH	Imidazole acetol-phosphate transaminase
E5E96_19030	ENOG4108UJE	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity)
E5E96_19035	ENOG4105CJV	Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase
E5E96_19050	ENOG4105BZU	Histidine kinase
E5E96_19055	ENOG4105C0S	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity)
E5E96_19060	ENOG4105K8F	Phosphoribosyl-amp cyclohydrolase
E5E96_19070	ENOG4105D29	Helix-turn-helix type 11 domain protein
E5E96_19075	ENOG4105CEY	Amp-dependent synthetase and ligase
E5E96_19080	ENOG4105CSX	c4-dicarboxylate anaerobic carrier
E5E96_19090	ENOG4107MBR	17 kDa surface antigen
E5E96_19100	ENOG4108UTP	(2Fe-2S)-binding domain protein
E5E96_19105	ENOG4108HR6	Dehydrogenase
E5E96_19110	ENOG4105C7W	Xanthine dehydrogenase
E5E96_19115	ENOG4105C7N	Xanthine uracil vitamin C permease
E5E96_19120	ENOG4107QUY	Guanine deaminase
E5E96_19125	ENOG4105C2W	permease
E5E96_19140	ENOG4107UUR	Chlorohydrolase aminohydrolase
E5E96_19145	ENOG4105BZ8	glutamate synthase
E5E96_19150	ENOG4105MFX	4-diphosphocytidyl-2c-methyl-d-erythritol synthase
E5E96_19155	ENOG4105MJ6	selenium-dependent hydroxylase accessory protein YqeC
E5E96_19160	ENOG4107P0T	Selenium-dependent molybdenum hydroxylase system protein, YqeB family
E5E96_19165	ENOG4108Q5Y	Membrane
E5E96_19170	ENOG4105C5B	carbamate kinase
E5E96_19180	ENOG4107S4Y	M20 DapE family protein YgeY
E5E96_19185	ENOG4107RCH	Diaminopropionate ammonia-lyase
E5E96_19190	ENOG4105IW6	Carbamoyltransferase
E5E96_19195	ENOG4108JUB	Transcriptional regulator
E5E96_19205	ENOG4108VWS	Yaeq family
E5E96_19215	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
E5E96_19220	ENOG4105CHU	acetyl-coa acetyltransferase
E5E96_19225	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
E5E96_19255	ENOG4105EMN	RNA polymerase sigma factor
E5E96_19265	ENOG4105CKF	membrane protein involved in aromatic hydrocarbon degradation
E5E96_19270	ENOG4105CKF	membrane protein involved in aromatic hydrocarbon degradation
E5E96_19280	ENOG4105CHU	acetyl-coa acetyltransferase
E5E96_19295	ENOG4105NBK	UPF0345 protein
E5E96_19300	ENOG4105EJQ	L-serine dehydratase
E5E96_19310	ENOG4105EJQ	L-serine dehydratase
E5E96_19315	ENOG4105CVE	Lytic murein transglycosylase
E5E96_19320	ENOG4105VNG	YcgL domain-containing protein
E5E96_19330	ENOG4107QMS	site-determining protein
E5E96_19335	ENOG4105VJP	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell (By similarity)
E5E96_19340	ENOG4108W5H	UPF0263 protein
E5E96_19345	ENOG4108VKV	Monofunctional biosynthetic peptidoglycan transglycosylase
E5E96_19350	ENOG4105XW2	UPF0263 protein
E5E96_19385	ENOG4108V3G	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity)
E5E96_19390	ENOG4108SXK	Transporter Drug Metabolite Exporter family
E5E96_19395	ENOG4108HH9	Catalyzes two reactions the first one is the production of beta-formyl glycinamide ribonucleotide (GAR) from formate, ATP and beta GAR
E5E96_19400	ENOG4107UW8	HAD-superfamily hydrolase subfamily IA variant 3
E5E96_19410	ENOG4108R6K	riboflavin synthase, subunit alpha
E5E96_19415	ENOG4105W1I	UPF0253 protein
E5E96_19420	ENOG4107QI1	Mate efflux family protein
E5E96_19450	ENOG4105CQ2	DNA polymerase
E5E96_19475	ENOG4105NWR	lipid A biosynthesis (Kdo)2-(Lauroyl)-lipid IVA acyltransferase
E5E96_19480	ENOG4105NWR	lipid A biosynthesis (Kdo)2-(Lauroyl)-lipid IVA acyltransferase
E5E96_19490	ENOG4105DUM	transcriptional regulator, lysR family
E5E96_19500	ENOG4105EFU	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin (By similarity)
E5E96_19505	ENOG4105CBN	LysR family transcriptional regulator
E5E96_19515	ENOG4105DHT	Metal Dependent Phosphohydrolase
E5E96_19525	ENOG4105BZU	Histidine kinase
E5E96_19530	ENOG4105CS2	ec 3.2.1.21
E5E96_19535	ENOG4108KB2	LysR family Transcriptional regulator
E5E96_19580	ENOG4105W5Q	DNA repair protein (RadC
E5E96_19605	ENOG4105CVR	type I restriction-modification system
E5E96_19620	ENOG4105VTR	Integrase
E5E96_19630	ENOG4105HF0	Membrane
E5E96_19635	ENOG4105D5Q	Arginine ornithine antiporter
E5E96_19645	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
E5E96_19650	ENOG4105E39	Enoyl-CoA hydratase
E5E96_19660	ENOG4105C1G	acyl-Coa dehydrogenase
E5E96_19665	ENOG4105C26	Dehydrogenase
E5E96_19670	ENOG4105C1G	acyl-Coa dehydrogenase
E5E96_19675	ENOG4107QX3	carboxylase
E5E96_19710	ENOG4106HK8	GPR1 FUN34 yaaH family protein
E5E96_19725	ENOG4105BZG	amino acid carrier protein
E5E96_19765	ENOG41060WC	Enoyl-CoA hydratase
E5E96_19780	ENOG41062QD	Membrane
E5E96_19785	ENOG4107QN1	sodium solute
E5E96_19790	ENOG4105C5H	ABC transporter
E5E96_19795	ENOG4105EIN	peptidylprolyl cis-trans isomerase
E5E96_19800	ENOG4105K70	DNA-binding protein
E5E96_19805	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
E5E96_19810	ENOG4105CHN	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
E5E96_19815	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
E5E96_19820	ENOG4105DEA	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation
E5E96_19840	ENOG4105D60	lipoprotein releasing system transmembrane protein
E5E96_19845	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
E5E96_19850	ENOG4105D60	lipoprotein releasing system transmembrane protein
E5E96_19865	ENOG4105CZI	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
E5E96_19870	ENOG4108J59	Extracellular solute-binding protein, family 5
E5E96_19875	ENOG4108IPJ	Membrane
E5E96_19885	ENOG4108BY2	phosphohistidine phosphatase
E5E96_19890	ENOG4107VK2	coenzyme PQQ biosynthesis protein PqqF
E5E96_19895	ENOG4105FQ6	thiopurine methyltransferase
E5E96_19910	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
E5E96_19935	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
E5E96_19940	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
E5E96_19945	ENOG4105DFH	Transport of potassium into the cell (By similarity)
E5E96_19970	ENOG4105DVS	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
E5E96_19975	ENOG4105D4P	Coproporphyrinogen iii oxidase
E5E96_19980	ENOG4108NVR	Methyl-accepting chemotaxis
E5E96_19985	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
E5E96_19990	ENOG4105CMY	5-enolpyruvylshikimate-3-phosphate synthase
E5E96_19995	ENOG4107QM1	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine (By similarity)
E5E96_20000	ENOG4105C10	Electron transfer flavoprotein
E5E96_20005	ENOG4105BZJ	Electron transfer flavoprotein
E5E96_20010	ENOG4105DWH	electron transfer flavoprotein-ubiquinone oxidoreductase
E5E96_20020	ENOG4105QZU	Inner membrane protein YfeZ
E5E96_20035	ENOG4105D05	Receptor
E5E96_20040	ENOG4105DQ5	transport system permease protein
E5E96_20045	ENOG4105TVJ	transport system, permease
E5E96_20050	ENOG4105E0A	ABC, transporter
E5E96_20055	ENOG4108TSE	Transferase
E5E96_20060	ENOG4108MES	Periplasmic binding protein
E5E96_20065	ENOG4105CEY	Amp-dependent synthetase and ligase
E5E96_20075	ENOG4105X17	23-dihydro-2,3-dihydroxybenzoate dehydrogenase
E5E96_20080	ENOG4105CEY	Amp-dependent synthetase and ligase
E5E96_20085	ENOG4105WQI	isochorismatase
E5E96_20090	ENOG4108IQC	2,3-dihydroxybenzoate-AMP ligase
E5E96_20100	ENOG4105F3T	(LipO)protein
E5E96_20110	ENOG4107QQ4	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans (By similarity)
E5E96_20115	ENOG4105BZU	Histidine kinase
E5E96_20130	ENOG4107RE1	Inosine-guanosine kinase
E5E96_20135	ENOG4105WJG	Glutathione
E5E96_20140	ENOG4105CFX	Catalyzes the ferrous insertion into protoporphyrin IX (By similarity)
E5E96_20145	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
E5E96_20155	ENOG4105CJX	Molecular chaperone. Has ATPase activity (By similarity)
E5E96_20165	ENOG4105F3K	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity)
E5E96_20170	ENOG4107H9G	Necessary for formate dehydrogenase activity (By similarity)
E5E96_20175	ENOG4108JUA	Transcriptional regulator
E5E96_20190	ENOG4108RC0	Electron transport protein
E5E96_20200	ENOG4105DFH	Transport of potassium into the cell (By similarity)
E5E96_20205	ENOG4108MFN	small subunit of hydrogenase-3, iron-sulfur protein (part of formate hydrogenlyase (FHL) complex)
E5E96_20210	ENOG4108JPZ	Monovalent cation H antiporter subunit D
E5E96_20215	ENOG4107TDF	Formate hydrogenlyase subunit 4
E5E96_20220	ENOG4105CQV	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
E5E96_20230	ENOG4105C47	NADH ubiquinone oxidoreductase 20 kda subunit
E5E96_20235	ENOG4105I6X	formate hydrogenlyase maturation
E5E96_20245	ENOG4105C1Y	Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis (By similarity)
E5E96_20250	ENOG4105EM7	Selenocysteine-specific translation elongation factor
E5E96_20260	ENOG4105WRB	Hydrogenase assembly chaperone hypC hupF
E5E96_20265	ENOG4105CQS	hydrogenase expression formation protein HypD
E5E96_20270	ENOG4105C45	hydrogenase expression formation protein (HypE)
E5E96_20275	ENOG4105WMM	Probably plays a role in a hydrogenase nickel cofactor insertion step (By similarity)
E5E96_20280	ENOG4107RSS	Hydrogenase accessory protein HypB
E5E96_20285	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
E5E96_20295	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
E5E96_20300	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
E5E96_20310	ENOG4108WGS	hydrogenase 2-specific chaperone
E5E96_20315	ENOG4108USZ	hydrogenase
E5E96_20320	ENOG4105DPX	Hydrogenase, large subunit
E5E96_20325	ENOG4105CJ5	hydrogenase 2 b cytochrome subunit
E5E96_20330	ENOG4105QA4	4Fe-4S Ferredoxin, iron-sulfur binding domain protein
E5E96_20335	ENOG4105E3S	small subunit
E5E96_20350	ENOG4105CBS	Chea signal transduction histidine kinase
E5E96_20355	ENOG4105C8Q	Methyl-accepting chemotaxis
E5E96_20360	ENOG4108V3W	Chemotaxis protein, CheW
E5E96_20365	ENOG4105BZU	Histidine kinase
E5E96_20370	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
E5E96_20375	ENOG4105BZU	Histidine kinase
E5E96_20380	ENOG4105C8Q	Methyl-accepting chemotaxis
E5E96_20385	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
E5E96_20410	ENOG4105CHH	sulfate transporter
E5E96_20460	ENOG4105C2C	drug resistance transporter, Bcr CflA
E5E96_20510	ENOG4108ZZK	Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source (By similarity)
E5E96_20515	ENOG4107QR9	Iron-sulfur cluster binding protein
E5E96_20525	ENOG4105DAA	L-lactate
E5E96_20530	ENOG4105CR8	Transcriptional regulator
E5E96_20540	ENOG4108UYE	Lactoylglutathione lyase
E5E96_20545	ENOG4105F2Z	3-oxoadipate enol-lactonase
E5E96_20570	ENOG4107QXP	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
E5E96_20575	ENOG4107QZM	n-acetylglutamate synthase
E5E96_20580	ENOG4105CFH	Aspartokinase
E5E96_20590	ENOG4107T7U	Sulfatase
E5E96_20595	ENOG4105EBE	Peptidase U61, LD-carboxypeptidase A
E5E96_20600	ENOG4108NRW	Phospholipase, patatin family
E5E96_20610	ENOG4105K8R	UPF0145 protein
E5E96_20630	ENOG4105CEP	NADH dehydrogenase
E5E96_20635	ENOG4105D0Y	UPF0227 protein
E5E96_20640	ENOG4105C2W	permease
E5E96_20645	ENOG4105DPN	Oligoendopeptidase f
E5E96_20650	ENOG4105DPN	Oligoendopeptidase f
E5E96_20665	ENOG4107RAB	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
E5E96_20670	ENOG4107QN8	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
E5E96_20705	ENOG4105K59	histidine triad (HIT) protein
E5E96_20710	ENOG4108NVR	Methyl-accepting chemotaxis
E5E96_20720	ENOG4105CD3	dihydroorotase
E5E96_20735	ENOG4105CK2	sodium dicarboxylate symporter
E5E96_20745	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
E5E96_20750	ENOG4105DU1	integral membrane protein, terc
E5E96_20755	ENOG4108JQ7	(ABC) transporter
E5E96_20760	ENOG4105C3U	ABC transporter
E5E96_20765	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
E5E96_20770	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
E5E96_20775	ENOG4107QSI	ABC, transporter
E5E96_20780	ENOG4105EZI	multiple antibiotic resistance (MarC)-related protein
E5E96_20790	ENOG4105C0A	alcohol dehydrogenase
E5E96_20795	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
E5E96_20800	ENOG4108HRK	Histidine kinase
E5E96_20805	ENOG4108NEV	two component transcriptional regulator, LytTR family
E5E96_20815	ENOG4105KK7	inner membrane protein YiaW
E5E96_20820	ENOG4105EFX	secretion protein, HlyD family
E5E96_20825	ENOG4105CFI	type iii restriction protein res subunit
E5E96_20830	ENOG4106HRJ	d-alanyl-d-alanine carboxypeptidase
E5E96_20835	ENOG41090BQ	Glutaredoxin
E5E96_20845	ENOG4105CHM	Aminotransferase
E5E96_20850	ENOG4105CSX	c4-dicarboxylate anaerobic carrier
E5E96_20855	ENOG4105RKW	reductase (By
E5E96_20930	ENOG4105EFV	Major head subunit
E5E96_20935	ENOG4108TVE	i protein
E5E96_20960	ENOG4105QIB	mu-like prophage Flumu protein gp29
E5E96_20970	ENOG4108Z6H	mu-like prophage Flumu protein gp27
E5E96_21085	ENOG4105M7P	phage repressor
E5E96_21100	ENOG4108PCN	EamA-like transporter family
E5E96_21105	ENOG4105DGN	Electron transport complex
E5E96_21110	ENOG4108R3D	Electron transport complex
E5E96_21120	ENOG4105D6A	Electron transport complex
E5E96_21135	ENOG4105CSM	endonuclease III
E5E96_21140	ENOG4108UYE	Lactoylglutathione lyase
E5E96_21145	ENOG4105EIY	sodium-type flagellar protein motY
E5E96_21155	ENOG4105DH5	Responsible for the end-turnover of tRNA specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis (By similarity)
E5E96_21160	ENOG4105D3Y	Na H antiporter
E5E96_21170	ENOG4105KA0	thioesterase Superfamily protein
E5E96_21180	ENOG4105CQB	FAD linked oxidase domain protein
E5E96_21190	ENOG4105EE5	Membrane protein terC
E5E96_21195	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
E5E96_21200	ENOG4105EKD	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism (By similarity)
E5E96_21205	ENOG4105D4U	had-superfamily hydrolase, subfamily iia
E5E96_21210	ENOG4105CKD	glutathione-regulated potassium-efflux system protein
E5E96_21220	ENOG4105CAQ	asparagine synthetase
E5E96_21230	ENOG4108TGY	Glutathione S-transferase
E5E96_21235	ENOG4108RXX	maleylacetoacetate isomerase
E5E96_21245	ENOG4105F1J	Homogentisate 1,2-dioxygenase
E5E96_21250	ENOG4105E6K	4-Hydroxyphenylpyruvate dioxygenase
E5E96_21260	ENOG4108W1A	pseudouridine synthase
E5E96_21265	ENOG4105BZU	Histidine kinase
E5E96_21270	ENOG4107RHT	methyl-accepting chemotaxis sensory transducer with Pas Pac sensor
E5E96_21280	ENOG4105FF5	Membrane
E5E96_21290	ENOG4105DIJ	Phosphoethanolamine transferase
E5E96_21330	ENOG41070MY	type iii secretion
E5E96_21335	ENOG41066XE	Type III export protein
E5E96_21365	ENOG4108KB1	transcriptional regulator, arac family
E5E96_21380	ENOG4106V6P	Exoenzyme S synthesis protein C
E5E96_21555	ENOG4105DAX	Pfam:DUF2983
E5E96_21605	ENOG4105F2I	Transposase
E5E96_21630	ENOG4108MN8	Membrane
E5E96_21635	ENOG4105EM2	membrane
E5E96_21640	ENOG4108Z0T	Part of a sulfur-relay system (By similarity)
E5E96_21645	ENOG4108S3P	Sporulation domain protein
E5E96_21650	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
E5E96_21655	ENOG4107QTG	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA (By similarity)
E5E96_21660	ENOG4105DI7	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity)
E5E96_21670	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
E5E96_21675	ENOG4105CJ0	Catalyzes the oxidation of erythronate-4-phosphate to 3- hydroxy-2-oxo-4-phosphonooxybutanoate (By similarity)
E5E96_21680	ENOG4105EYK	Phosphatidylglycerophosphatase B
E5E96_21685	ENOG4105D01	(LipO)protein
E5E96_21715	ENOG4108HRN	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate (By similarity)
E5E96_21720	ENOG4105CF9	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation (By similarity)
E5E96_21730	ENOG4105C85	amino acid
E5E96_21775	ENOG4105N5T	Radical SAM Protein
E5E96_21780	ENOG4105CBC	glutamate synthase
E5E96_21785	ENOG4105BZ8	glutamate synthase
E5E96_21790	ENOG4105CDA	abc transporter atp-binding protein
E5E96_21795	ENOG4105DRP	amino acid AbC transporter
E5E96_21800	ENOG4105EAB	amino acid AbC transporter
E5E96_21815	ENOG4108Z4X	TRANSCRIPTIONal
E5E96_21840	ENOG4105C1J	atp-dependent rna helicase
E5E96_21845	ENOG4108MK9	spermidine N(1)-acetyltransferase
E5E96_21875	ENOG4107QS8	(LipO)protein
E5E96_21880	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
E5E96_21885	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
E5E96_21890	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
E5E96_21895	ENOG4105DUK	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity)
E5E96_21905	ENOG4105MK2	5-formyltetrahydrofolate cyclo-ligase
E5E96_21910	ENOG4105E66	phosphoriboisomerase A
E5E96_21915	ENOG4108JQ1	Dehydrogenase
E5E96_21920	ENOG41080IJ	Diacylglycerol kinase
E5E96_21925	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
E5E96_21935	ENOG41080WI	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system (By similarity)
E5E96_21940	ENOG4108ESU	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Involved in the translocation of the substrate across the membrane (By similarity)
E5E96_21945	ENOG4105BZU	Histidine kinase
E5E96_21955	ENOG4105CZX	twitching motility protein
E5E96_21960	ENOG4107QQ4	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans (By similarity)
E5E96_21985	ENOG4108ZJT	translation initiation factor, Sui1
E5E96_22020	ENOG410620I	Diguanylate cyclase
E5E96_22040	ENOG4105YYA	enhanced serine sensitivity protein SseB
E5E96_22045	ENOG4105C8N	cysteinyl-tRNA synthetase
E5E96_22050	ENOG4108R5K	PPIases accelerate the folding of proteins (By similarity)
E5E96_22060	ENOG4105F10	Catalyzes the hydrolysis of the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1- phosphate (lipid X) and UMP (By similarity)
E5E96_22065	ENOG4105DVI	reductase, NrfD
E5E96_22070	ENOG4105D3S	4Fe-4S Ferredoxin, iron-sulfur binding domain protein
E5E96_22075	ENOG4105JJ8	Cytochrome c nitrite reductase, pentaheme subunit
E5E96_22105	ENOG4107SDU	Methyl-accepting chemotaxis
E5E96_22125	ENOG4105RDA	repressor
E5E96_22160	ENOG4105WH1	Two component transcriptional regulator luxr family
E5E96_22165	ENOG4105CET	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria (By similarity)
E5E96_22170	ENOG4105W49	UPF0434 protein
E5E96_22175	ENOG4105CHD	Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) (By similarity)
E5E96_22185	ENOG4108EQH	DNA internalization-related competence protein ComEC Rec2
E5E96_22200	ENOG4105D7A	ATP-binding protein
E5E96_22205	ENOG4105QYK	bacteriophage lambda Bor protein homolog
E5E96_22210	ENOG4105QYK	bacteriophage lambda Bor protein homolog
E5E96_22225	ENOG4105D3C	The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters (By similarity)
E5E96_22230	ENOG4105CGB	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system (By similarity)
E5E96_22235	ENOG4105E0C	molybdate abc transporter
E5E96_22240	ENOG4108S6J	ABC transporter, periplasmic molybdate-binding protein
E5E96_22245	ENOG4108ZAF	Molybdopterin
E5E96_22250	ENOG4105M00	molybdopterin converting factor, subunit 1
E5E96_22255	ENOG4108YXW	Together with MoaA, is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
E5E96_22260	ENOG4108RIR	Molybdenum cofactor biosynthesis protein
E5E96_22265	ENOG4105CUW	cytochrome C-TYPE protein
E5E96_22275	ENOG4105GXZ	Ferredoxin-type protein NapH
E5E96_22280	ENOG4108BGM	Quinol dehydrogenase periplasmic component
E5E96_22285	ENOG4107QIW	Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity)
E5E96_22295	ENOG4108ZNS	ferredoxin-type protein NapF
E5E96_22300	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
E5E96_22310	ENOG4105WH1	Two component transcriptional regulator luxr family
E5E96_22320	ENOG4105BZU	Histidine kinase
E5E96_22330	ENOG4105CHW	UPF0052 protein
E5E96_22340	ENOG4105E7A	Glutamine amidotransferase
E5E96_22345	ENOG4105F55	Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate (By similarity)
E5E96_22350	ENOG4107QPN	acyl-Coa dehydrogenase
E5E96_22360	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
E5E96_22365	ENOG4105CJW	magnesium transporter
E5E96_22380	ENOG4108ZW7	flagellar rod assembly protein muramidase flgj
E5E96_22385	ENOG4105D92	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity)
E5E96_22390	ENOG4107W7W	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity)
E5E96_22395	ENOG4105CGA	flagellar basal-body rod protein FlgG
E5E96_22400	ENOG4108KPB	Flagellar basal-body rod protein FlgF
E5E96_22405	ENOG4105BZE	flagellar hook protein, FlgE
E5E96_22415	ENOG4108ZC9	flagellar basal-body rod protein flgc
E5E96_22420	ENOG4105K88	Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body (By similarity)
E5E96_22425	ENOG4105BZU	Histidine kinase
E5E96_22435	ENOG4107ESN	Flagella basal body P-ring formation protein flgA
E5E96_22450	ENOG4108RE9	Phosphodiesterase
E5E96_22455	ENOG4107QSI	ABC, transporter
E5E96_22465	ENOG4105I08	Pseudouridine synthase
E5E96_22470	ENOG4105CPI	Metal Dependent Phosphohydrolase
E5E96_22480	ENOG4107T9Z	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
E5E96_22485	ENOG4105F1A	Pyruvate formate-lyase
E5E96_22495	ENOG4105N2W	Transcriptional regulator
E5E96_22500	ENOG4108594	Permease of the drug metabolite transporter
E5E96_22530	ENOG4105VEQ	Cold shock protein
E5E96_22535	ENOG4107QSN	dihydrolipoamide acetyltransferase
E5E96_22540	ENOG4105CPP	Dehydrogenase, E1 component
E5E96_22545	ENOG4107RUY	(E1 component), alpha subunit
E5E96_22560	ENOG4105KR1	Trans-acting protein required for termination of DNA replication. Binds to DNA replication terminator sequences (terA to terF) to prevent the passage of replication forks. The termination efficiency will be affected by the affinity of this protein for the terminator sequence (By similarity)
E5E96_22570	ENOG4108YXG	UPF0502 protein
E5E96_22580	ENOG4108KPN	Confers a modal distribution of chain length on the O- antigen component of lipopolysaccharide (LPS). Gives rise to a reduced number of short chain molecules and increases in numbers of longer molecules, with a modal value of 13 (in strain O111 M92) and of 17 (in strain K12)
E5E96_22585	ENOG4105DBZ	Dtdp-4-dehydrorhamnose reductase
E5E96_22595	ENOG4106ECQ	phosphomannomutase
E5E96_22600	ENOG4105CJT	Mannose-1-phosphate guanylyltransferase
E5E96_22610	ENOG4108UW5	maltose o-acetyltransferase
E5E96_22630	ENOG4108UW5	maltose o-acetyltransferase
E5E96_22650	ENOG4108URP	Dtdp-4-dehydrorhamnose 3,5-epimerase
E5E96_22655	ENOG4108I19	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis (By similarity)
E5E96_22660	ENOG4105C1B	dTDP-glucose 4-6-dehydratase
E5E96_22665	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein