locus-tag	class	description
C2U40_00030	ENOG4105GVR	general secretion pathway protein D
C2U40_00045	ENOG4107QHF	type ii secretion system protein e
C2U40_00050	ENOG4105D7Q	type ii secretion system
C2U40_00095	ENOG4105DFF	Rod shape-determining protein mreb
C2U40_00100	ENOG4105N3I	Involved in formation and maintenance of cell shape (By similarity)
C2U40_00105	ENOG4105VQ7	Rod shape-determining protein MreD
C2U40_00110	ENOG4108Z03	MAF-like protein
C2U40_00115	ENOG4105C03	ribonuclease
C2U40_00120	ENOG4105QD6	exported protein
C2U40_00135	ENOG4105D1U	peptidase U62 modulator of DNA gyrase
C2U40_00150	ENOG4105CSH	Transporter
C2U40_00160	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
C2U40_00165	ENOG4105BZU	Histidine kinase
C2U40_00170	ENOG4105QD0	anti-sigma regulatory factor serine threonine protein kinase
C2U40_00175	ENOG4107MMM	Anti-sigma-factor antagonist
C2U40_00180	ENOG4107SDU	Methyl-accepting chemotaxis
C2U40_00195	ENOG4105F0S	class B acid phosphatase
C2U40_00205	ENOG4105CGZ	zinc metallopeptidase
C2U40_00215	ENOG4108HU6	Metal dependent phosphohydrolase
C2U40_00235	ENOG4105EEQ	Na H antiporter
C2U40_00240	ENOG4105C3R	Methionine synthase
C2U40_00245	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
C2U40_00250	ENOG4105CWM	branched-chain amino acid transport system II carrier protein
C2U40_00260	ENOG4105ETX	regulatoR
C2U40_00270	ENOG4107Y8H	Aerolysin toxin
C2U40_00275	ENOG4105CBF	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction (By similarity)
C2U40_00280	ENOG4108UV6	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity)
C2U40_00285	ENOG4105D06	uba thif-type nad fad binding protein
C2U40_00295	ENOG4105CA8	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity)
C2U40_00300	ENOG4105D41	biosynthesis protein thiH
C2U40_00325	ENOG4108WEF	Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1B (PBP1b) (By similarity)
C2U40_00345	ENOG4105BZU	Histidine kinase
C2U40_00350	ENOG4105C44	Serine transporter
C2U40_00355	ENOG4108TPP	exopolysaccharide synthesis
C2U40_00370	ENOG4105N0V	mono-oxygenase ydhR
C2U40_00375	ENOG4105KVH	Transcriptional regulator
C2U40_00400	ENOG4105E0K	tonB-dependent siderophore receptor
C2U40_00415	ENOG4105CBT	Fructose-1,6-bisphosphatase
C2U40_00430	ENOG4105ECF	c-methyltransferase
C2U40_00435	ENOG41076E6	Uroporphyrinogen-III Synthase
C2U40_00440	ENOG4105D6W	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity)
C2U40_00445	ENOG4107T0K	Adenylate cyclase
C2U40_00450	ENOG4106CJB	Phospholipase Carboxylesterase
C2U40_00455	ENOG4105XQ6	frataxin-like protein
C2U40_00460	ENOG4105CU5	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity)
C2U40_00465	ENOG4105E4Z	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan (By similarity)
C2U40_00475	ENOG4108IYS	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
C2U40_00480	ENOG4105DFC	had-superfamily hydrolase, subfamily ia, variant
C2U40_00490	ENOG4107RYR	Transcriptional regulator, Crp Fnr family
C2U40_00500	ENOG4108Z86	Glutamine amidotransferase
C2U40_00505	ENOG410667J	hydrolase
C2U40_00520	ENOG4105CJ1	ABC, transporter
C2U40_00530	ENOG4108I62	cina-like protein
C2U40_00535	ENOG4105E4Y	Endoribonuclease that initiates mRNA decay (By similarity)
C2U40_00540	ENOG4105CVG	Homoserine O-transsuccinylase
C2U40_00550	ENOG4108YXU	transcriptional regulator AsnC family
C2U40_00555	ENOG4105E0M	Sulfatase
C2U40_00575	ENOG4105KT7	mgtC SapB transporter
C2U40_00595	ENOG4105EMU	Dehydrogenase
C2U40_00600	ENOG4105DZW	Dipeptidase
C2U40_00615	ENOG4108I6A	alcohol dehydrogenase
C2U40_00625	ENOG4108IQK	o-acetylhomoserine
C2U40_00635	ENOG4105KNR	Activates the small RNA gene sgrS under glucose- phosphate stress conditions as well as yfdZ. Represses its own transcription under both stress and non-stress conditions. Might act as a sensor of the intracellular accumulation of phosphoglucose by binding these molecules in its C-terminal solute-binding domain (By similarity)
C2U40_00655	ENOG4107IFA	Lipase (EC 3.1.1.3)
C2U40_00670	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
C2U40_00675	ENOG4108UB4	uncharacterized protein ygjQ
C2U40_00680	ENOG4107MM9	BNR Asp-box repeat-containing protein
C2U40_00690	ENOG4105HMV	Fimbrial protein
C2U40_00700	ENOG4106PG1	outer membrane usher protein
C2U40_00705	ENOG4108FZ9	Chaperone
C2U40_00710	ENOG4108MDY	Fimbrial
C2U40_00725	ENOG4105CEY	Amp-dependent synthetase and ligase
C2U40_00730	ENOG4105DNI	Converts SHCHC to OSB (By similarity)
C2U40_00735	ENOG4108IPT	Naphthoate synthase
C2U40_00740	ENOG4107J5P	Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC). Is also able to catalyze the hydrolysis of the thioester bond in palmitoyl-CoA in vitro (By similarity)
C2U40_00745	ENOG4105C4A	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC) (By similarity)
C2U40_00750	ENOG4105E4F	Isochorismate synthase
C2U40_00755	ENOG4105EIS	1,4-dihydroxy-2-naphthoate octaprenyltransferase
C2U40_00780	ENOG4105C1J	atp-dependent rna helicase
C2U40_00785	ENOG4105D9N	nucleoside
C2U40_00790	ENOG4107K5X	Membrane-bound metal-dependent hydrolase
C2U40_00805	ENOG4108UPT	UPF0178 protein
C2U40_00830	ENOG4105C3N	Participates in control of cell volume in low-osmolarity conditions (By similarity)
C2U40_00835	ENOG4105E61	Mannitol repressor protein
C2U40_00840	ENOG4107SQ3	mannitol-1-phosphate 5-dehydrogenase
C2U40_00845	ENOG4105CTS	PTS system mannitol-specific
C2U40_00860	ENOG4108IEC	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction (By similarity)
C2U40_00865	ENOG4105CXD	Specific inhibitor of chromosomal initiation of replication in vitro. Binds the three 13-mers in the origin (oriC) to block initiation of replication (By similarity)
C2U40_00870	ENOG4105NNS	Autoinducer synthesis protein
C2U40_00875	ENOG4105VJY	transcriptional regulator
C2U40_00880	ENOG4108ZUB	Lysine exporter protein (Lyse ygga)
C2U40_00885	ENOG4107RNS	bifunctional 2',3'-cyclic nucleotide 2'-phosphodiesterase 3'-nucleotidase periplasmic
C2U40_00890	ENOG4108XTF	Outer Membrane Lipoprotein
C2U40_00895	ENOG4108R6G	acetyltransferase
C2U40_00915	ENOG4105DJ1	Phosphoenolpyruvate Carboxylase
C2U40_00920	ENOG4105F4C	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress (By similarity)
C2U40_00925	ENOG4105VEJ	Heat shock protein
C2U40_00935	ENOG4105GVR	general secretion pathway protein D
C2U40_00940	ENOG4107QHF	type ii secretion system protein e
C2U40_00945	ENOG4105D7Q	type ii secretion system
C2U40_00950	ENOG4108VAU	general secretion pathway protein G
C2U40_00995	ENOG4108UDW	Transcriptional regulator, luxr family
C2U40_01000	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
C2U40_01005	ENOG4107Y3D	HAD-superfamily hydrolase subfamily IA variant 3
C2U40_01010	ENOG4107RK2	ADP-ribose diphosphatase NudE
C2U40_01015	ENOG4108RNI	3'(2')5'-bisphosphate nucleotidase
C2U40_01020	ENOG4105C44	Serine transporter
C2U40_01025	ENOG4108Z7R	Chaperone CsaA
C2U40_01030	ENOG41086D8	Transcriptional regulator
C2U40_01035	ENOG4105GGQ	This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis (By similarity)
C2U40_01040	ENOG4105C28	cystathionine
C2U40_01045	ENOG4105CFH	Aspartokinase
C2U40_01050	ENOG4105CCA	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle (By similarity)
C2U40_01060	ENOG4105C0N	N-acetylglutamate semialdehyde dehydrogenase
C2U40_01065	ENOG4105CAS	nag kinase
C2U40_01075	ENOG4105CDH	Citrulline--aspartate ligase
C2U40_01080	ENOG4105CH7	arginosuccinase
C2U40_01105	ENOG4108UW5	maltose o-acetyltransferase
C2U40_01110	ENOG4107PU6	Membrane
C2U40_01115	ENOG4105DE7	Sulfate ABC transporter periplasmic sulfate-binding protein
C2U40_01125	ENOG4108I5D	sulfate abc transporter
C2U40_01130	ENOG4105ECW	sulfate abc transporter
C2U40_01135	ENOG4108IJ6	ABC transporter
C2U40_01140	ENOG4107R11	Transcriptional regulator
C2U40_01145	ENOG4108M1A	Chitin-binding protein
C2U40_01150	ENOG4105C8Q	Methyl-accepting chemotaxis
C2U40_01185	ENOG4107RE3	peptidase, S41
C2U40_01205	ENOG4105G0K	glycine radical enzyme YjjI family
C2U40_01210	ENOG41076CZ	activating enzyme
C2U40_01225	ENOG4105CGF	Aromatic amino acid aminotransferase
C2U40_01255	ENOG4108V1J	Has antioxidant activity. Could remove peroxides or H(2)O(2) (By similarity)
C2U40_01265	ENOG4105C1J	atp-dependent rna helicase
C2U40_01280	ENOG4108QYW	Bacterial hemolysins are exotoxins that attack blood cell membranes and cause cell rupture. Beta-hemolysin is a phospholipase C with specific activity toward sphingomyelins. Has a high specificity for sphingomyelin, hydrolyzes lysophosphatidylcholine at a much lower rate, but has no activity towards phosphatidylcholine, phosphatidylethanolamine, or phosphatidylserine (By similarity)
C2U40_01285	ENOG4107RHT	methyl-accepting chemotaxis sensory transducer with Pas Pac sensor
C2U40_01300	ENOG4105XTV	UPF0231 protein
C2U40_01305	ENOG4108IXP	Carbohydrate diacid transcriptional activator CdaR
C2U40_01310	ENOG4107QQ0	gntp family
C2U40_01315	ENOG4105BZW	Glycerate kinase
C2U40_01330	ENOG4105HEI	LysR family (Transcriptional regulator
C2U40_01335	ENOG4105D9N	nucleoside
C2U40_01345	ENOG4108YZN	class I peptide chain release factor
C2U40_01350	ENOG4108YZA	Nitrogen regulatory protein pii
C2U40_01365	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
C2U40_01370	ENOG4105EZR	dyp-type peroxidase family protein
C2U40_01375	ENOG410682Y	Regulates arginine biosynthesis genes (By similarity)
C2U40_01380	ENOG4105E5Z	arginine transporter ATP-binding subunit
C2U40_01385	ENOG4106PMH	Extracellular solute-binding protein family 3
C2U40_01390	ENOG4105GBT	ABC transporter
C2U40_01395	ENOG4105DMR	ABC, transporter
C2U40_01400	ENOG4105C80	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
C2U40_01405	ENOG4108UV7	flagellar protein motX
C2U40_01410	ENOG4105CJJ	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity)
C2U40_01420	ENOG4108JU6	CBS domain protein
C2U40_01425	ENOG4106KVJ	cytochrome C assembly protein
C2U40_01430	ENOG4105CB9	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
C2U40_01435	ENOG4105K5M	30s ribosomal protein S16
C2U40_01440	ENOG4108ZR6	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity)
C2U40_01445	ENOG4105D6X	Specifically methylates guanosine-37 in various tRNAs (By similarity)
C2U40_01450	ENOG4108YY1	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity)
C2U40_01460	ENOG4105IRT	Sequence-specific endonuclease that cleaves unmethylated GATC sequences. It is involved in DNA mismatch repair (By similarity)
C2U40_01470	ENOG4105EJF	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity)
C2U40_01475	ENOG4108HRM	phosphoenolpyruvate--protein phosphotransferase
C2U40_01480	ENOG4105C3B	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity)
C2U40_01485	ENOG4105C0V	Provides the sole de novo source of dTMP for DNA biosynthesis (By similarity)
C2U40_01490	ENOG4105DRC	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity)
C2U40_01500	ENOG41063Z6	transcriptional regulator, lysR family
C2U40_01505	ENOG41080HT	Transcriptional regulator, arsr family
C2U40_01510	ENOG4105KQV	Binds directly to 16S ribosomal RNA (By similarity)
C2U40_01515	ENOG4105CJR	Integral membrane protein (MviN
C2U40_01520	ENOG4105DTN	riboflavin biosynthesis protein ribF
C2U40_01525	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
C2U40_01530	ENOG4105M02	This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity)
C2U40_01535	ENOG41090X3	Peptidyl-prolyl cis-trans isomerase
C2U40_01540	ENOG4105C48	Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) (By similarity)
C2U40_01600	ENOG4105C4K	Nad synthetase
C2U40_01605	ENOG4108YZA	Nitrogen regulatory protein pii
C2U40_01615	ENOG4106762	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD) (By similarity)
C2U40_01620	ENOG4106TD9	Diguanylate cyclase
C2U40_01625	ENOG4105C40	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity)
C2U40_01630	ENOG4105C2N	RNA methyltransferase TrmH family group 3
C2U40_01645	ENOG4107YB6	acetyltransferase, (GNAT) family
C2U40_01665	ENOG4105C56	H( )-stimulated, divalent metal cation uptake system (By similarity)
C2U40_01670	ENOG4108ZDX	Binds together with S18 to 16S ribosomal RNA (By similarity)
C2U40_01675	ENOG4105VH8	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity)
C2U40_01680	ENOG4105K9Q	Binds to the 23S rRNA (By similarity)
C2U40_01685	ENOG4105DP0	ferredoxin-NADP reductase
C2U40_01710	ENOG4105W39	Membrane
C2U40_01720	ENOG4105D9M	gamma-glutamylcysteine synthetase
C2U40_01730	ENOG4108IQE	Amp-dependent synthetase and ligase
C2U40_01740	ENOG41080E2	ribosomal-protein-alanine acetyltransferase
C2U40_01750	ENOG4107R4Q	Functions as an ATPase. May play a role in metal insertion (metal-chelatase) or as a chaperone (By similarity)
C2U40_01765	ENOG4105BZU	Histidine kinase
C2U40_01775	ENOG4105VNT	transposase (IS4 family) protein
C2U40_01795	ENOG4108MJ3	acetyltransferase
C2U40_01800	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
C2U40_01810	ENOG4105WDY	DNA (cytosine-5-)-methyltransferase
C2U40_01825	ENOG4105DWY	Agmatine deiminase
C2U40_01830	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
C2U40_01845	ENOG4107YH7	Beta-lactamase (EC 3.5.2.6)
C2U40_01860	ENOG4105C1J	atp-dependent rna helicase
C2U40_01865	ENOG4107Y60	(LipO)protein
C2U40_01875	ENOG4106B0W	Curli production assembly transport component CsgG
C2U40_01895	ENOG4107V4F	S-adenosyl-l-methionine hydroxide adenosyltransferase
C2U40_01900	ENOG4105CA0	peroxidase
C2U40_01925	ENOG4105EA8	2-Nitropropane dioxygenase
C2U40_01960	ENOG4105E09	nadh pyrophosphatase
C2U40_01965	ENOG4105E0F	Histidine kinase
C2U40_01970	ENOG4105E3W	Two component transcriptional regulator (Winged helix family
C2U40_01975	ENOG4105DJY	efflux transporter, rnd family, mfp subunit
C2U40_01980	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
C2U40_01985	ENOG4105CT1	(ABC) transporter
C2U40_01990	ENOG4105CDA	abc transporter atp-binding protein
C2U40_01995	ENOG4105E5Q	amino acid AbC transporter
C2U40_02000	ENOG4105E5Q	amino acid AbC transporter
C2U40_02005	ENOG4108IYI	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine (By similarity)
C2U40_02030	ENOG4105CYX	Short-chain dehydrogenase reductase Sdr
C2U40_02035	ENOG4105CE6	Adenylation and deadenylation of glutamate--ammonia ligase (By similarity)
C2U40_02045	ENOG4105C8Q	Methyl-accepting chemotaxis
C2U40_02050	ENOG4105EYW	Ion transport protein
C2U40_02055	ENOG4106MWK	domain protein
C2U40_02060	ENOG4105C26	Dehydrogenase
C2U40_02065	ENOG4105E09	nadh pyrophosphatase
C2U40_02070	ENOG4105CFZ	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III (By similarity)
C2U40_02075	ENOG4105DKQ	ROK family
C2U40_02080	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
C2U40_02085	ENOG4105BZA	Phosphoglycerate kinase
C2U40_02090	ENOG4105D2N	Aldolase
C2U40_02095	ENOG4105CJP	fad dependent oxidoreductase
C2U40_02105	ENOG4105CSG	Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps (By similarity)
C2U40_02110	ENOG4105VF7	tolerance protein
C2U40_02135	ENOG4105Y75	tpr repeat protein
C2U40_02145	ENOG4108IYU	L-aspartate oxidase
C2U40_02150	ENOG4105EMN	RNA polymerase sigma factor
C2U40_02155	ENOG41069PW	sigma-e factor negative regulatory protein
C2U40_02170	ENOG4105C4S	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity)
C2U40_02175	ENOG4105C3F	Signal peptidase i
C2U40_02190	ENOG41071DT	Involved in DNA repair and RecF pathway recombination (By similarity)
C2U40_02195	ENOG4105CSZ	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate (By similarity)
C2U40_02205	ENOG4105D2N	Aldolase
C2U40_02210	ENOG4105CE4	GlcNAc 6-P deacetylase
C2U40_02215	ENOG4108YTN	IIa component
C2U40_02220	ENOG4105F3R	pts system mannose fructose sorbose family iid
C2U40_02230	ENOG4108RG5	PTS system N-acetylgalactosamine-specific transporter subunit IIB
C2U40_02235	ENOG4105E70	isomerase
C2U40_02240	ENOG4105C6Q	that is required for full activity and stability of the Y subunit. Could have a chaperone-like function for the proper and stable folding of
C2U40_02245	ENOG4105E98	transcriptional regulator DeoR family
C2U40_02250	ENOG4108VBV	N-Acetylmuramoyl-L-alanine amidase
C2U40_02255	ENOG4108W15	Protein of unknown function (DUF1456)
C2U40_02260	ENOG4105BZU	Histidine kinase
C2U40_02265	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
C2U40_02270	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
C2U40_02275	ENOG4105DXN	mazG family
C2U40_02280	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
C2U40_02285	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
C2U40_02290	ENOG4105XX3	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity)
C2U40_02295	ENOG4105CE5	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) (By similarity)
C2U40_02300	ENOG4108UH8	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (By similarity)
C2U40_02305	ENOG4106NZV	Responsible for synthesis of pseudouridine from uracil- 13 in transfer RNAs (By similarity)
C2U40_02310	ENOG4105CV2	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates (By similarity)
C2U40_02315	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
C2U40_02320	ENOG4108UM1	dedA family
C2U40_02325	ENOG4108K5P	(LipO)protein
C2U40_02335	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
C2U40_02340	ENOG4105VCC	30S ribosomal protein S21
C2U40_02345	ENOG4105KTH	gatB Yqey
C2U40_02350	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
C2U40_02355	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
C2U40_02385	ENOG4105C12	Phosphoribosylglycinamide synthetase
C2U40_02390	ENOG4105DC1	bifunctional purine biosynthesis protein purh
C2U40_02400	ENOG4105NAE	bifunctional deaminase-reductase domain protein
C2U40_02410	ENOG4105CSA	Coproporphyrinogen iii oxidase
C2U40_02415	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
C2U40_02425	ENOG4105D9R	oxidoreductase
C2U40_02440	ENOG4105D9U	N-acetyltransferase
C2U40_02445	ENOG4108Z9I	-acetyltransferase
C2U40_02460	ENOG4105EV4	Multidrug resistance protein mdtH
C2U40_02475	ENOG4105DS2	Anaerobic c4-dicarboxylate transporter
C2U40_02480	ENOG4108IJ0	Aspartate ammonia-lyase
C2U40_02485	ENOG4108YH1	overproduction of this protein in Escherichia coli inhibits the F plasmid-mediated exclusion of bacteriophage T7
C2U40_02490	ENOG4107QI1	Mate efflux family protein
C2U40_02495	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
C2U40_02500	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
C2U40_02510	ENOG4105BZU	Histidine kinase
C2U40_02520	ENOG4105D3G	Pseudouridine synthase
C2U40_02525	ENOG4105BZK	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair (By similarity)
C2U40_02550	ENOG4108NIW	Leucine export protein LeuE
C2U40_02590	ENOG410679B	prophage CP4-57 regulatory protein alpA
C2U40_02630	ENOG4105XUP	Phage derived protein Gp49-like (DUF891)
C2U40_02640	ENOG4108NF7	phage-type endonuclease
C2U40_02690	ENOG4108YGG	dna repair protein
C2U40_02735	ENOG4105MAW	Antitoxin component of a toxin-antitoxin (TA) module. Labile antitoxin that counteracts the effect of the CbtA (YeeV) toxin. It does not bind to the cognate toxin but instead binds to MreB and FtsZ (the toxin targets), enhancing their polymerization by forming higher-order bundles
C2U40_02740	ENOG4105CVR	type I restriction-modification system
C2U40_02745	ENOG4105EKX	Restriction modification system DNA (Specificity
C2U40_02765	ENOG4105F5W	AtP-binding protein
C2U40_02770	ENOG4105D70	Integrase catalytic subunit
C2U40_02795	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
C2U40_02800	ENOG4105D70	Integrase catalytic subunit
C2U40_02805	ENOG4105F5W	AtP-binding protein
C2U40_02840	ENOG4105VY0	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters (By similarity)
C2U40_02845	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
C2U40_02855	ENOG4107V40	secretion protein, HlyD family
C2U40_02885	ENOG4105I93	response regulator
C2U40_02890	ENOG4105DUX	Transporter
C2U40_02895	ENOG4105C3Y	UTP-glucose-1-phosphate uridylyltransferase
C2U40_02900	ENOG41083P1	competence protein ComEA helix-hairpin-helix repeat protein
C2U40_02905	ENOG4108RNI	3'(2')5'-bisphosphate nucleotidase
C2U40_02910	ENOG4105K9H	YciI-like protein
C2U40_02915	ENOG4107835	probably involved in intracellular septation (By similarity)
C2U40_02920	ENOG4105DY8	decarboxylase
C2U40_02925	ENOG4108UT2	hemolysin iii
C2U40_02930	ENOG4105D0C	transport protein
C2U40_02940	ENOG4107R88	Chemotaxis protein (CheV)
C2U40_02945	ENOG4108UJV	acyl-CoA thioesterase i
C2U40_02950	ENOG4108I0Y	(ABC) transporter
C2U40_02955	ENOG4105CV6	ABC transporter, permease
C2U40_02960	ENOG4105ECP	epimerase
C2U40_02965	ENOG4105BZU	Histidine kinase
C2U40_02970	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
C2U40_02975	ENOG4105IIU	Aminopeptidase
C2U40_02980	ENOG4105CZ1	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity)
C2U40_02985	ENOG41090ED	Protein with unknown function (DUF469)
C2U40_02990	ENOG4105CSV	Glutaminase
C2U40_02995	ENOG4107RM6	sulfurtransferase
C2U40_03000	ENOG4105RX7	peptidase S8 and S53, subtilisin, kexin, sedolisin
C2U40_03005	ENOG4105SUV	lipoprotein YgdR
C2U40_03010	ENOG4105BZ1	(ABC) transporter
C2U40_03055	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
C2U40_03095	ENOG4107G87	m6 family metalloprotease domain protein
C2U40_03105	ENOG4105KQT	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome (By similarity)
C2U40_03110	ENOG4105BZU	Histidine kinase
C2U40_03130	ENOG4105VYA	Uncharacterized conserved protein (DUF2132)
C2U40_03135	ENOG4105DJ4	phosphatidylserine decarboxylase
C2U40_03140	ENOG4105E06	May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity)
C2U40_03145	ENOG4108RBP	3'-to-5' exoribonuclease specific for small oligoribonucleotides (By similarity)
C2U40_03185	ENOG4105VEQ	Cold shock protein
C2U40_03195	ENOG4105C8Q	Methyl-accepting chemotaxis
C2U40_03200	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
C2U40_03205	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
C2U40_03255	ENOG4109015	Biopolymer transport protein exbD tolR
C2U40_03275	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
C2U40_03280	ENOG4108I5X	binding-protein-dependent transport systems inner membrane Component
C2U40_03285	ENOG4108IYQ	Binding-protein-dependent transport systems inner membrane component
C2U40_03300	ENOG4108JQ7	(ABC) transporter
C2U40_03310	ENOG4105CIN	aminoacyl-histidine dipeptidase
C2U40_03320	ENOG4105DYA	Acts on guanine, xanthine and to a lesser extent hypoxanthine (By similarity)
C2U40_03325	ENOG4105V1F	Fermentation respiration switch protein
C2U40_03330	ENOG4108UVK	Binds to the sigma-S subunit of RNA polymerase, activating expression of sigma-S-regulated genes. Stimulates RNA polymerase holoenzyme formation and may bind to several other sigma factors, such as sigma-70 and sigma-32 (By similarity)
C2U40_03340	ENOG4105C2S	Catalyzes the NADPH dependent reduction of L-gamma- glutamyl 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate (By similarity)
C2U40_03365	ENOG4105DD7	kinase (PfkB family
C2U40_03370	ENOG4105D53	Catalyzes the hydrolysis of pseudouridine 5'-phosphate (PsiMP) to ribose 5-phosphate and uracil (By similarity)
C2U40_03375	ENOG4108UHE	carbonic anhydrase
C2U40_03380	ENOG4105CA0	peroxidase
C2U40_03415	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
C2U40_03445	ENOG4105C84	Histidine ammonia-lyase
C2U40_03470	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
C2U40_03480	ENOG4105C2D	reductase
C2U40_03495	ENOG4108RIR	Molybdenum cofactor biosynthesis protein
C2U40_03505	ENOG4105DWK	Membrane
C2U40_03510	ENOG4107XM3	UPF0442 protein
C2U40_03520	ENOG4108IJ7	Glycine betaine
C2U40_03525	ENOG4108HQS	Glycine betaine
C2U40_03530	ENOG4105GIJ	Glycine betaine
C2U40_03535	ENOG4105ET3	Reduction of activated sulfate into sulfite (By similarity)
C2U40_03540	ENOG4105ET1	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate (By similarity)
C2U40_03545	ENOG4107EER	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity)
C2U40_03550	ENOG4107TIF	Phenazine biosynthesis protein, PhzF family
C2U40_03555	ENOG4105CRK	lysyL-tRNA synthetase
C2U40_03565	ENOG4105C8Q	Methyl-accepting chemotaxis
C2U40_03570	ENOG4105D6U	Sodium Glutamate Symporter
C2U40_03575	ENOG4105HDK	L-asparaginase
C2U40_03580	ENOG4105VUT	cytoplasmic protein
C2U40_03600	ENOG4105D07	Signal peptide peptidase, SppA
C2U40_03605	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
C2U40_03610	ENOG41069NU	Nitroreductase
C2U40_03625	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
C2U40_03635	ENOG4105CIS	alcohol dehydrogenase
C2U40_03640	ENOG4105HEI	LysR family (Transcriptional regulator
C2U40_03645	ENOG4105CI1	PTS System
C2U40_03650	ENOG4108IA2	Sodium pantothenate symporter
C2U40_03660	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
C2U40_03665	ENOG4105KM4	Acetyl-CoA carboxylase, biotin carboxyl carrier protein
C2U40_03670	ENOG4108Z38	Catalyzes a trans-dehydration via an enolate intermediate (By similarity)
C2U40_03675	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
C2U40_03685	ENOG4105BZU	Histidine kinase
C2U40_03705	ENOG4109039	Involved in the biogenesis of TorA. Acts on TorA before the insertion of the molybdenum cofactor and, as a result, probably favors a conformation of the apoenzyme that is competent for acquiring the cofactor (By similarity)
C2U40_03715	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
C2U40_03730	ENOG4108Z11	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes (By similarity)
C2U40_03735	ENOG4105D1W	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity)
C2U40_03755	ENOG4108UTT	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity)
C2U40_03760	ENOG4107YIM	Involved in the transcription termination process (By similarity)
C2U40_03765	ENOG4105CG2	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity)
C2U40_03770	ENOG4108ZAI	phosphatidylglycerophosphatase a
C2U40_03775	ENOG4108JQ6	ABC transporter
C2U40_03785	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
C2U40_03795	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
C2U40_03800	ENOG4105CTB	Polyprenyl synthetase
C2U40_03805	ENOG41067QG	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
C2U40_03810	ENOG4105E14	MotA TolQ exbB proton channel
C2U40_03815	ENOG4105ER2	Ompa motb domain protein
C2U40_03820	ENOG4108UKH	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
C2U40_03830	ENOG4105HBR	Rna-binding protein
C2U40_03835	ENOG4105F7M	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit (By similarity)
C2U40_03840	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
C2U40_03845	ENOG4105EEI	dihydropteroate synthase
C2U40_03850	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
C2U40_03855	ENOG4105CP7	Triose-phosphate isomerase
C2U40_03875	ENOG4105K7D	Required for maturation of 30S ribosomal subunits (By similarity)
C2U40_03880	ENOG4105CHV	Transcription elongation factor NusA
C2U40_03885	ENOG4107QHU	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
C2U40_03890	ENOG4105KG7	Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity)
C2U40_03895	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
C2U40_03900	ENOG4105K77	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity)
C2U40_03905	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
C2U40_03910	ENOG4105VNT	transposase (IS4 family) protein
C2U40_03915	ENOG4105E5W	Transporter
C2U40_03920	ENOG4105BZU	Histidine kinase
C2U40_03925	ENOG41090EX	DsrE family
C2U40_03940	ENOG4105EQ6	Hydrolyzes dipeptides containing N-terminal aspartate residues. May play a role in allowing the cell to use peptide aspartate to spare carbon otherwise required for the synthesis of the aspartate family of amino acids (By similarity)
C2U40_03950	ENOG4108NEV	two component transcriptional regulator, LytTR family
C2U40_03955	ENOG4108HRK	Histidine kinase
C2U40_03960	ENOG4108ZXC	Two component transcriptional regulator, luxr family
C2U40_03965	ENOG4105BZU	Histidine kinase
C2U40_03970	ENOG4105QA4	4Fe-4S Ferredoxin, iron-sulfur binding domain protein
C2U40_03975	ENOG4106WHD	Tetrathionate reductase
C2U40_03980	ENOG4105DB1	molybdopterin oxidoreductase
C2U40_04010	ENOG4107N1Q	ErfK YbiS YcfS YnhG family protein
C2U40_04030	ENOG41071R3	Low-potential electron donor to a number of redox enzymes (By similarity)
C2U40_04035	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
C2U40_04040	ENOG4105M2E	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell (By similarity)
C2U40_04045	ENOG4105T95	Thiol disulfide interChange protein
C2U40_04050	ENOG4105C2R	Single-stranded-DNA-specific exonuclease (RecJ)
C2U40_04055	ENOG4107SWG	transcriptional regulator MERR family
C2U40_04070	ENOG4108IUB	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
C2U40_04075	ENOG4105MJ9	esterase
C2U40_04085	ENOG4105C0G	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity)
C2U40_04095	ENOG4108BDP	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity)
C2U40_04100	ENOG4108Z43	UPF0250 protein
C2U40_04105	ENOG4105DZ1	carboxypeptidase
C2U40_04110	ENOG4105K6T	rare lipoprotein A
C2U40_04115	ENOG4105CVE	Lytic murein transglycosylase
C2U40_04120	ENOG4105CNI	cell division protein FtsW
C2U40_04125	ENOG4105CJN	penicillin-binding protein
C2U40_04130	ENOG4108UXA	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA (By similarity)
C2U40_04135	ENOG4105KEM	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation (By similarity)
C2U40_04140	ENOG4108Z1W	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity)
C2U40_04160	ENOG4105C8T	Leucyl-tRNA synthetase
C2U40_04165	ENOG4107PAI	alpha helical protein
C2U40_04170	ENOG4105CE8	Transfers the fatty acyl group on membrane lipoproteins (By similarity)
C2U40_04175	ENOG4108JU5	Magnesium and cobalt efflux protein
C2U40_04180	ENOG4105KGE	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA (By similarity)
C2U40_04185	ENOG4105C9A	Phoh family
C2U40_04190	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
C2U40_04195	ENOG4105EAK	ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family
C2U40_04200	ENOG4106XMA	In vivo, quickly hydrolyzes the ureidoacrylate peracid to avoid toxicity, but can also hydrolyzes ureidoacrylate that is formed spontaneously from ureidoacrylate peracid. One of the products of hydrolysis, carbamate, hydrolyzes spontaneously, thereby releasing one of the pyrimidine rings nitrogen atoms as ammonia and one of its carbons as CO2 (By similarity)
C2U40_04210	ENOG4105BZU	Histidine kinase
C2U40_04225	ENOG4105EVE	HAD-superfamily hydrolase subfamily IA variant 3
C2U40_04235	ENOG4105BZU	Histidine kinase
C2U40_04245	ENOG4105C5I	Dehydrogenase
C2U40_04255	ENOG4108R5S	membrane
C2U40_04260	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
C2U40_04275	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
C2U40_04295	ENOG4105DHQ	Histidine kinase
C2U40_04300	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
C2U40_04330	ENOG4105DA6	Catalyzes the conversion of 5-methoxyuridine (mo5U) to uridine-5-oxyacetic acid (cmo5U) at position 34 in tRNA. May also participate in the methylation of uridine-5-oxyacetic acid (cmo5U) to uridine-5-oxyacetic acid methyl ester (mcmo5U) (By similarity)
C2U40_04335	ENOG4105T0Z	Conserved Protein
C2U40_04355	ENOG4108VP9	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane (By similarity)
C2U40_04360	ENOG4108WJH	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane (By similarity)
C2U40_04365	ENOG4105E33	succinate dehydrogenase
C2U40_04380	ENOG4108QXE	glycerophosphoryl diester phosphodiesterase
C2U40_04385	ENOG4105EGS	Mechanosensitive ion channel
C2U40_04395	ENOG4105DR5	peptidase
C2U40_04410	ENOG4105EJC	lysr family transcriptional regulator
C2U40_04425	ENOG4105C8Q	Methyl-accepting chemotaxis
C2U40_04430	ENOG4105C5Q	Transcriptional regulator
C2U40_04435	ENOG4108JQC	penicillin-binding protein 1A
C2U40_04460	ENOG4105E4G	Type IV pilus
C2U40_04465	ENOG4105KHV	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
C2U40_04470	ENOG4105D49	3-dehydroquinate synthase
C2U40_04480	ENOG4105DFE	Dna adenine methylase
C2U40_04495	ENOG4105DJV	ribulose-phosphate 3-epimerase
C2U40_04500	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
C2U40_04505	ENOG4105C31	Tryptophanyl-tRNA synthetase
C2U40_04520	ENOG4105C8Y	Acetylornithine aminotransferase
C2U40_04530	ENOG4105C26	Dehydrogenase
C2U40_04540	ENOG4107VXZ	Hydrolase
C2U40_04550	ENOG4105D95	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin (By similarity)
C2U40_04560	ENOG4105CG3	alpha amylase, catalytic region
C2U40_04570	ENOG41060QA	UPF0267 protein
C2U40_04580	ENOG4108I5U	Uridine phosphorylase
C2U40_04585	ENOG4106Z1T	Nicotinamide Mononucleotide Transporter
C2U40_04590	ENOG4107QWE	)-transporter
C2U40_04675	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
C2U40_04750	ENOG4105DFP	Integrase
C2U40_04755	ENOG4105C3G	gtp-binding protein
C2U40_04760	ENOG4108ZPD	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity)
C2U40_04765	ENOG4105CGH	5'-nucleotidase
C2U40_04770	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
C2U40_04780	ENOG4105CTR	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol (By similarity)
C2U40_04785	ENOG4105C1U	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein (By similarity)
C2U40_04790	ENOG4105C7E	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) (By similarity)
C2U40_04795	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
C2U40_04800	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
C2U40_04810	ENOG41063JG	Transcriptional regulator
C2U40_04815	ENOG4105CXR	Phospho-2-dehydro-3-deoxyoctonate aldolase
C2U40_04820	ENOG4105CK2	sodium dicarboxylate symporter
C2U40_04825	ENOG4108VKA	Acts as a radical domain for damaged PFL and possibly other radical proteins (By similarity)
C2U40_04830	ENOG4105D5S	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine (By similarity)
C2U40_04845	ENOG4105CW3	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
C2U40_04850	ENOG4105BZG	amino acid carrier protein
C2U40_04855	ENOG4105F8C	transglutaminase domain-containing protein
C2U40_04865	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
C2U40_04870	ENOG41066YJ	Beta-lactamase
C2U40_04875	ENOG4105DUX	Transporter
C2U40_04880	ENOG4107Y66	Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity)
C2U40_04885	ENOG4108UJU	UPF0301 protein
C2U40_04895	ENOG4105D7Z	glutathione synthase
C2U40_04900	ENOG4105QF0	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity)
C2U40_04910	ENOG4105GPY	SprT protein
C2U40_04915	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
C2U40_04920	ENOG4105CV1	Transketolase (EC 2.2.1.1)
C2U40_04925	ENOG4105KME	endoribonuclease L-psp
C2U40_04935	ENOG4105TMR	Functions as a holding molecular chaperone (holdase) which stabilizes unfolding intermediates and rapidly releases them in an active form once stress has abated. Plays an important role in protecting cells from severe heat shock and starvation, as well as in acid resistance of stationary-phase cells. It catalyzes the conversion of methylglyoxal (MG) to D-lactate in a single glutathione (GSH)-independent step (By similarity)
C2U40_04940	ENOG4105ED7	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling (By similarity)
C2U40_04945	ENOG4105DR5	peptidase
C2U40_04950	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
C2U40_04955	ENOG4107WCA	isomerase
C2U40_04965	ENOG4108V1U	phospholipid-binding protein
C2U40_04970	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
C2U40_04985	ENOG4105C87	Aminotransferase class I and II
C2U40_04995	ENOG4105C5Q	Transcriptional regulator
C2U40_05000	ENOG4105UBK	short-chain dehydrogenase reductase
C2U40_05005	ENOG4105ERU	peptidase
C2U40_05010	ENOG4105EY2	Catalyzes the hydrolysis of N(2)-succinylarginine into N(2)-succinylornithine, ammonia and CO(2) (By similarity)
C2U40_05015	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
C2U40_05030	ENOG4107RHT	methyl-accepting chemotaxis sensory transducer with Pas Pac sensor
C2U40_05035	ENOG4105E2D	ec 3.2.1.52
C2U40_05040	ENOG4105RD7	BadF BadG BcrA BcrD
C2U40_05050	ENOG4108JQ7	(ABC) transporter
C2U40_05060	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
C2U40_05070	ENOG4108J59	Extracellular solute-binding protein, family 5
C2U40_05075	ENOG4105BZU	Histidine kinase
C2U40_05095	ENOG4105XIQ	Protein of unknown function (DUF2517)
C2U40_05125	ENOG4107SDU	Methyl-accepting chemotaxis
C2U40_05135	ENOG4108ESY	Metal dependent phosphohydrolase
C2U40_05140	ENOG4105DR8	Membrane
C2U40_05145	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
C2U40_05150	ENOG4105C6R	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor (By similarity)
C2U40_05155	ENOG4108IUZ	ABC transporter
C2U40_05160	ENOG4107A5B	Binding-protein-dependent transport systems, inner membrane component
C2U40_05170	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
C2U40_05175	ENOG4105BZU	Histidine kinase
C2U40_05180	ENOG4105HD0	Transcriptional regulator of molybdate metabolism, LysR family
C2U40_05185	ENOG4107H9G	Necessary for formate dehydrogenase activity (By similarity)
C2U40_05200	ENOG4105BZ4	penicillin-binding protein
C2U40_05230	ENOG4108IEG	Formate dehydrogenase Alpha subunit
C2U40_05230	ENOG4108IEG	Formate dehydrogenase Alpha subunit
C2U40_05235	ENOG4105QAX	Iron-sulfur
C2U40_05245	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
C2U40_05250	ENOG4107R1I	NAD-dependent malic enzyme
C2U40_05265	ENOG4105C2W	permease
C2U40_05270	ENOG4105HHQ	6-phosphogluconolactonase (EC 3.1.1.31)
C2U40_05285	ENOG4105EGS	Mechanosensitive ion channel
C2U40_05290	ENOG4105CA9	Pyruvate kinase
C2U40_05305	ENOG4105CKD	glutathione-regulated potassium-efflux system protein
C2U40_05315	ENOG4105DH7	May be involved in recombination (By similarity)
C2U40_05325	ENOG4107RH8	nuclease SbcCD subunit D
C2U40_05330	ENOG4105EYH	Exonuclease
C2U40_05335	ENOG4105EYH	Exonuclease
C2U40_05345	ENOG4105CPW	cytochrome b561
C2U40_05355	ENOG4105BZU	Histidine kinase
C2U40_05360	ENOG4105C5Y	PTS System
C2U40_05370	ENOG4105KZ7	phosphocarrier protein hpr
C2U40_05375	ENOG4105C6T	cysteine synthase
C2U40_05380	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
C2U40_05395	ENOG4108R96	Methyltransferase, YaeB family
C2U40_05415	ENOG4108JJ8	(ABC) transporter
C2U40_05420	ENOG4108JJ9	ABC, transporter
C2U40_05435	ENOG41065U4	response regulator
C2U40_05445	ENOG4108YYX	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. Modulates RNA-binding and helicase activities of the degradosome (By similarity)
C2U40_05460	ENOG4105VS7	Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue. This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon. When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation (By similarity)
C2U40_05465	ENOG4106FVC	RNA methyltransferase
C2U40_05480	ENOG4105D5I	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate (By similarity)
C2U40_05485	ENOG4105D98	threonine synthase
C2U40_05520	ENOG4108QW8	Purine nucleoside phosphorylase deoD-type
C2U40_05535	ENOG4105BZU	Histidine kinase
C2U40_05540	ENOG4105C8E	extradiol ring-cleavage dioxygenase class IIi protein subunit b
C2U40_05545	ENOG4108V1T	peptidylprolyl cis-trans isomerase
C2U40_05560	ENOG4105CUB	amino acid
C2U40_05575	ENOG4105CUB	amino acid
C2U40_05580	ENOG4108JPW	Aminotransferase
C2U40_05585	ENOG4105C26	Dehydrogenase
C2U40_05590	ENOG4107VRI	Transcriptional regulator
C2U40_05595	ENOG4105CJP	fad dependent oxidoreductase
C2U40_05610	ENOG4108YX2	DNA-binding protein
C2U40_05615	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
C2U40_05625	ENOG4105Q26	Siderophore-interacting protein
C2U40_05630	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
C2U40_05635	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
C2U40_05640	ENOG4105DJY	efflux transporter, rnd family, mfp subunit
C2U40_05650	ENOG4105E2M	Manganese-dependent inorganic pyrophosphatase
C2U40_05660	ENOG4105C4F	May be involved in recombinational repair of damaged DNA (By similarity)
C2U40_05665	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
C2U40_05670	ENOG4105K90	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
C2U40_05675	ENOG4105CFG	Acts as a chaperone (By similarity)
C2U40_05680	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
C2U40_05695	ENOG4105D7K	pfkb domain protein
C2U40_05730	ENOG41080HT	Transcriptional regulator, arsr family
C2U40_05740	ENOG4105KFG	YeeE YedE family protein
C2U40_05755	ENOG4105BZU	Histidine kinase
C2U40_05760	ENOG4107RMF	Catalyzes both the ATP-dependent activation of exogenously supplied lipoate to lipoyl-AMP and the transfer of the activated lipoyl onto the lipoyl domains of lipoate-dependent enzymes (By similarity)
C2U40_05780	ENOG4108IJF	Heavy metal efflux pump, CzcA
C2U40_05785	ENOG4105EP1	Efflux transporter rnd family, mfp subunit
C2U40_05805	ENOG4105CGK	Exodeoxyribonuclease III
C2U40_05820	ENOG4105E5W	Transporter
C2U40_05875	ENOG4105E2S	oxidase) subunit II
C2U40_05880	ENOG4105BZ9	Cytochrome C oxidase, subunit I
C2U40_05885	ENOG4105CCU	oxidase (Subunit III)
C2U40_05890	ENOG41090KH	cytochrome o ubiquinol oxidase (subunit iv)
C2U40_05895	ENOG4105F1R	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group (By similarity)
C2U40_05900	ENOG4107RDB	Major Facilitator
C2U40_05910	ENOG4105BZU	Histidine kinase
C2U40_05915	ENOG4108SV3	Tmao reductase system periplasmic protein tort
C2U40_05925	ENOG4106WF9	DNA-binding transcriptional regulator TorR
C2U40_05930	ENOG4105CUW	cytochrome C-TYPE protein
C2U40_05935	ENOG4108EM1	reductase
C2U40_05940	ENOG4109039	Involved in the biogenesis of TorA. Acts on TorA before the insertion of the molybdenum cofactor and, as a result, probably favors a conformation of the apoenzyme that is competent for acquiring the cofactor (By similarity)
C2U40_05980	ENOG4108YGG	dna repair protein
C2U40_06020	ENOG4105F52	Transcriptional regulator
C2U40_06035	ENOG4105C5B	carbamate kinase
C2U40_06040	ENOG4107REC	cytoplasmic protein
C2U40_06045	ENOG4107R1Q	Membrane protein FdrA
C2U40_06050	ENOG4106XMA	In vivo, quickly hydrolyzes the ureidoacrylate peracid to avoid toxicity, but can also hydrolyzes ureidoacrylate that is formed spontaneously from ureidoacrylate peracid. One of the products of hydrolysis, carbamate, hydrolyzes spontaneously, thereby releasing one of the pyrimidine rings nitrogen atoms as ammonia and one of its carbons as CO2 (By similarity)
C2U40_06065	ENOG410679B	prophage CP4-57 regulatory protein alpA
C2U40_06095	ENOG4105D9N	nucleoside
C2U40_06115	ENOG4105CAF	HipA N-terminal domain protein
C2U40_06125	ENOG4105S2T	inner membrane protein YbcI
C2U40_06140	ENOG4105F2I	Transposase
C2U40_06150	ENOG4105F6H	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate (By similarity)
C2U40_06155	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
C2U40_06160	ENOG4105DK0	Indole-3-glycerol phosphate synthase
C2U40_06165	ENOG4108I0Q	anthranilate phosphoribosyltransferase
C2U40_06170	ENOG4108EFP	Anthranilate synthase component II
C2U40_06175	ENOG4105CRQ	synthase (Component I)
C2U40_06180	ENOG4105DB7	PHP domain protein
C2U40_06185	ENOG4107RTD	sua5 ycio yrdc ywlc family protein
C2U40_06195	ENOG4105K8I	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves (By similarity)
C2U40_06200	ENOG4105FE9	pseudouridine synthase
C2U40_06205	ENOG4105C29	acyl-CoA thioesterase
C2U40_06220	ENOG4108IG5	Transcriptional regulator
C2U40_06225	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
C2U40_06230	ENOG4105BZS	acriflavin resistance protein
C2U40_06235	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
C2U40_06240	ENOG4105C1B	dTDP-glucose 4-6-dehydratase
C2U40_06245	ENOG4108I19	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis (By similarity)
C2U40_06260	ENOG4108V3E	phosphoribosylglycinamide formyltransferase
C2U40_06285	ENOG4105CAQ	asparagine synthetase
C2U40_06295	ENOG4107QQG	Dehydrogenase
C2U40_06315	ENOG4105D3Q	Sugar transferase
C2U40_06325	ENOG4105C1B	dTDP-glucose 4-6-dehydratase
C2U40_06330	ENOG4105DBZ	Dtdp-4-dehydrorhamnose reductase
C2U40_06340	ENOG4108URP	Dtdp-4-dehydrorhamnose 3,5-epimerase
C2U40_06345	ENOG4108QY5	Ferric enterobactin transport protein
C2U40_06355	ENOG4108YXG	UPF0502 protein
C2U40_06365	ENOG4105KR1	Trans-acting protein required for termination of DNA replication. Binds to DNA replication terminator sequences (terA to terF) to prevent the passage of replication forks. The termination efficiency will be affected by the affinity of this protein for the terminator sequence (By similarity)
C2U40_06380	ENOG4107RUY	(E1 component), alpha subunit
C2U40_06385	ENOG4105CPP	Dehydrogenase, E1 component
C2U40_06390	ENOG4107QSN	dihydrolipoamide acetyltransferase
C2U40_06395	ENOG4105VEQ	Cold shock protein
C2U40_06420	ENOG4105E43	Extracellular solute-binding protein, family 5
C2U40_06425	ENOG4108594	Permease of the drug metabolite transporter
C2U40_06430	ENOG4105N2W	Transcriptional regulator
C2U40_06435	ENOG4105C6N	Formate acetyltransferase
C2U40_06440	ENOG4105F1A	Pyruvate formate-lyase
C2U40_06445	ENOG4107T9Z	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
C2U40_06455	ENOG4105CPI	Metal Dependent Phosphohydrolase
C2U40_06460	ENOG4105I08	Pseudouridine synthase
C2U40_06470	ENOG4107QSI	ABC, transporter
C2U40_06475	ENOG4108RE9	Phosphodiesterase
C2U40_06490	ENOG4107ESN	Flagella basal body P-ring formation protein flgA
C2U40_06495	ENOG4107R88	Chemotaxis protein (CheV)
C2U40_06500	ENOG4105BZU	Histidine kinase
C2U40_06505	ENOG4105K88	Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body (By similarity)
C2U40_06510	ENOG4108ZC9	flagellar basal-body rod protein flgc
C2U40_06520	ENOG4105BZE	flagellar hook protein, FlgE
C2U40_06525	ENOG4108KPB	Flagellar basal-body rod protein FlgF
C2U40_06530	ENOG4105CGA	flagellar basal-body rod protein FlgG
C2U40_06535	ENOG4107W7W	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity)
C2U40_06540	ENOG4105D92	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity)
C2U40_06545	ENOG4108ZW7	flagellar rod assembly protein muramidase flgj
C2U40_06550	ENOG4105E1Q	flagellar hook-associated protein
C2U40_06555	ENOG4105DTJ	flagellar hook-associated protein
C2U40_06560	ENOG4105CJW	magnesium transporter
C2U40_06565	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
C2U40_06570	ENOG4107QPN	acyl-Coa dehydrogenase
C2U40_06575	ENOG4105F55	Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate (By similarity)
C2U40_06580	ENOG4105E7A	Glutamine amidotransferase
C2U40_06590	ENOG4105CHW	UPF0052 protein
C2U40_06600	ENOG4105BZU	Histidine kinase
C2U40_06610	ENOG4105WH1	Two component transcriptional regulator luxr family
C2U40_06615	ENOG4105BZU	Histidine kinase
C2U40_06620	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
C2U40_06625	ENOG4108ZNS	ferredoxin-type protein NapF
C2U40_06635	ENOG4107QIW	Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity)
C2U40_06640	ENOG4108BGM	Quinol dehydrogenase periplasmic component
C2U40_06645	ENOG4105GXZ	Ferredoxin-type protein NapH
C2U40_06655	ENOG4105CUW	cytochrome C-TYPE protein
C2U40_06660	ENOG4108RIR	Molybdenum cofactor biosynthesis protein
C2U40_06665	ENOG4108YXW	Together with MoaA, is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
C2U40_06670	ENOG4105M00	molybdopterin converting factor, subunit 1
C2U40_06675	ENOG4108ZAF	Molybdopterin
C2U40_06680	ENOG4108S6J	ABC transporter, periplasmic molybdate-binding protein
C2U40_06685	ENOG4105E0C	molybdate abc transporter
C2U40_06690	ENOG4105CGB	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system (By similarity)
C2U40_06695	ENOG4105D3C	The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters (By similarity)
C2U40_06710	ENOG4105QYK	bacteriophage lambda Bor protein homolog
C2U40_06715	ENOG4105QYK	bacteriophage lambda Bor protein homolog
C2U40_06720	ENOG4105D7A	ATP-binding protein
C2U40_06750	ENOG4105BZ1	(ABC) transporter
C2U40_06755	ENOG4105CHD	Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) (By similarity)
C2U40_06760	ENOG4105W49	UPF0434 protein
C2U40_06765	ENOG4105CET	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria (By similarity)
C2U40_06770	ENOG4105WH1	Two component transcriptional regulator luxr family
C2U40_06775	ENOG4105CII	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity)
C2U40_06805	ENOG4107SDU	Methyl-accepting chemotaxis
C2U40_06810	ENOG4108NVR	Methyl-accepting chemotaxis
C2U40_06835	ENOG4105JJ8	Cytochrome c nitrite reductase, pentaheme subunit
C2U40_06840	ENOG4105D3S	4Fe-4S Ferredoxin, iron-sulfur binding domain protein
C2U40_06845	ENOG4105DVI	reductase, NrfD
C2U40_06850	ENOG4105F10	Catalyzes the hydrolysis of the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1- phosphate (lipid X) and UMP (By similarity)
C2U40_06860	ENOG4108R5K	PPIases accelerate the folding of proteins (By similarity)
C2U40_06865	ENOG4105C8N	cysteinyl-tRNA synthetase
C2U40_06890	ENOG410620I	Diguanylate cyclase
C2U40_06925	ENOG4108ZJT	translation initiation factor, Sui1
C2U40_06950	ENOG4107QQ4	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans (By similarity)
C2U40_06955	ENOG4105CZX	twitching motility protein
C2U40_06965	ENOG4105BZU	Histidine kinase
C2U40_06970	ENOG4108ESU	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Involved in the translocation of the substrate across the membrane (By similarity)
C2U40_06975	ENOG41080WI	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system (By similarity)
C2U40_06985	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
C2U40_06990	ENOG41080IJ	Diacylglycerol kinase
C2U40_06995	ENOG4108JQ1	Dehydrogenase
C2U40_07000	ENOG4105E66	phosphoriboisomerase A
C2U40_07005	ENOG4105MK2	5-formyltetrahydrofolate cyclo-ligase
C2U40_07015	ENOG4105DUK	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity)
C2U40_07020	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
C2U40_07025	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
C2U40_07030	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
C2U40_07035	ENOG4107QS8	(LipO)protein
C2U40_07060	ENOG4108MK9	spermidine N(1)-acetyltransferase
C2U40_07065	ENOG4105C1J	atp-dependent rna helicase
C2U40_07090	ENOG4108Z4X	TRANSCRIPTIONal
C2U40_07105	ENOG4105EAB	amino acid AbC transporter
C2U40_07110	ENOG4105DRP	amino acid AbC transporter
C2U40_07115	ENOG4105CDA	abc transporter atp-binding protein
C2U40_07120	ENOG4105BZ8	glutamate synthase
C2U40_07125	ENOG4105CBC	glutamate synthase
C2U40_07130	ENOG4105N5T	Radical SAM Protein
C2U40_07140	ENOG4105C42	Type I secretion membrane fusion protein (HlyD
C2U40_07190	ENOG4105C85	amino acid
C2U40_07200	ENOG4105CF9	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation (By similarity)
C2U40_07205	ENOG4108HRN	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate (By similarity)
C2U40_07245	ENOG4105D01	(LipO)protein
C2U40_07250	ENOG4105EYK	Phosphatidylglycerophosphatase B
C2U40_07255	ENOG4105CJ0	Catalyzes the oxidation of erythronate-4-phosphate to 3- hydroxy-2-oxo-4-phosphonooxybutanoate (By similarity)
C2U40_07260	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
C2U40_07270	ENOG4105DI7	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity)
C2U40_07275	ENOG4107QTG	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA (By similarity)
C2U40_07280	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
C2U40_07285	ENOG4108S3P	Sporulation domain protein
C2U40_07290	ENOG4108Z0T	Part of a sulfur-relay system (By similarity)
C2U40_07295	ENOG4105EM2	membrane
C2U40_07300	ENOG4108MN8	Membrane
C2U40_07415	ENOG4106V6P	Exoenzyme S synthesis protein C
C2U40_07430	ENOG4108KB1	transcriptional regulator, arac family
C2U40_07460	ENOG41066XE	Type III export protein
C2U40_07465	ENOG41070MY	type iii secretion
C2U40_07505	ENOG4105DIJ	Phosphoethanolamine transferase
C2U40_07515	ENOG4105FF5	Membrane
C2U40_07525	ENOG4107RHT	methyl-accepting chemotaxis sensory transducer with Pas Pac sensor
C2U40_07530	ENOG4105BZU	Histidine kinase
C2U40_07535	ENOG4108W1A	pseudouridine synthase
C2U40_07545	ENOG4105E6K	4-Hydroxyphenylpyruvate dioxygenase
C2U40_07550	ENOG4105F1J	Homogentisate 1,2-dioxygenase
C2U40_07565	ENOG4108RXX	maleylacetoacetate isomerase
C2U40_07570	ENOG4108TGY	Glutathione S-transferase
C2U40_07580	ENOG4105CAQ	asparagine synthetase
C2U40_07590	ENOG4105CKD	glutathione-regulated potassium-efflux system protein
C2U40_07595	ENOG4105D4U	had-superfamily hydrolase, subfamily iia
C2U40_07610	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
C2U40_07615	ENOG4105EE5	Membrane protein terC
C2U40_07625	ENOG4105CQB	FAD linked oxidase domain protein
C2U40_07635	ENOG4105KA0	thioesterase Superfamily protein
C2U40_07645	ENOG4105D3Y	Na H antiporter
C2U40_07650	ENOG4105DH5	Responsible for the end-turnover of tRNA specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis (By similarity)
C2U40_07660	ENOG4105EIY	sodium-type flagellar protein motY
C2U40_07665	ENOG4108UYE	Lactoylglutathione lyase
C2U40_07670	ENOG4105CSM	endonuclease III
C2U40_07675	ENOG4105DZB	Electron transport complex
C2U40_07685	ENOG4105D6A	Electron transport complex
C2U40_07695	ENOG4108R3D	Electron transport complex
C2U40_07700	ENOG4105DGN	Electron transport complex
C2U40_07705	ENOG4108PCN	EamA-like transporter family
C2U40_07715	ENOG4107SDU	Methyl-accepting chemotaxis
C2U40_07725	ENOG4105RKW	reductase (By
C2U40_07730	ENOG4105CSX	c4-dicarboxylate anaerobic carrier
C2U40_07735	ENOG4105CHM	Aminotransferase
C2U40_07745	ENOG41090BQ	Glutaredoxin
C2U40_07750	ENOG4106HRJ	d-alanyl-d-alanine carboxypeptidase
C2U40_07755	ENOG4105CFI	type iii restriction protein res subunit
C2U40_07760	ENOG4105EFX	secretion protein, HlyD family
C2U40_07765	ENOG4105KK7	inner membrane protein YiaW
C2U40_07775	ENOG4108NEV	two component transcriptional regulator, LytTR family
C2U40_07780	ENOG4108HRK	Histidine kinase
C2U40_07785	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
C2U40_07790	ENOG4108EKI	Dehydrogenase
C2U40_07800	ENOG4105EZI	multiple antibiotic resistance (MarC)-related protein
C2U40_07805	ENOG4107QSI	ABC, transporter
C2U40_07810	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
C2U40_07815	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
C2U40_07820	ENOG4105C3U	ABC transporter
C2U40_07825	ENOG4108JQ7	(ABC) transporter
C2U40_07830	ENOG4105DU1	integral membrane protein, terc
C2U40_07840	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
C2U40_07850	ENOG4105CK2	sodium dicarboxylate symporter
C2U40_07865	ENOG4105CD3	dihydroorotase
C2U40_07875	ENOG4108NVR	Methyl-accepting chemotaxis
C2U40_07880	ENOG4105K59	histidine triad (HIT) protein
C2U40_07915	ENOG4107QN8	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
C2U40_07920	ENOG4107RAB	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
C2U40_07930	ENOG4105CKW	Inner membrane protein yedI
C2U40_07935	ENOG4105DPN	Oligoendopeptidase f
C2U40_07940	ENOG4105DPN	Oligoendopeptidase f
C2U40_07945	ENOG4105C2W	permease
C2U40_07955	ENOG4105CEP	NADH dehydrogenase
C2U40_07975	ENOG4105K8R	UPF0145 protein
C2U40_07985	ENOG4108NRW	Phospholipase, patatin family
C2U40_07990	ENOG4105EBE	Peptidase U61, LD-carboxypeptidase A
C2U40_07995	ENOG4107T7U	Sulfatase
C2U40_08005	ENOG4105CFH	Aspartokinase
C2U40_08010	ENOG4107QZM	n-acetylglutamate synthase
C2U40_08015	ENOG4107QXP	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
C2U40_08040	ENOG4105F2Z	3-oxoadipate enol-lactonase
C2U40_08045	ENOG4108UYE	Lactoylglutathione lyase
C2U40_08055	ENOG4105CR8	Transcriptional regulator
C2U40_08060	ENOG4105DAA	L-lactate
C2U40_08070	ENOG4107QR9	Iron-sulfur cluster binding protein
C2U40_08075	ENOG4108ZZK	Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source (By similarity)
C2U40_08105	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
C2U40_08115	ENOG4105C2C	drug resistance transporter, Bcr CflA
C2U40_08165	ENOG4105CHH	sulfate transporter
C2U40_08190	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
C2U40_08195	ENOG4105C8Q	Methyl-accepting chemotaxis
C2U40_08200	ENOG4105BZU	Histidine kinase
C2U40_08205	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
C2U40_08210	ENOG4105BZU	Histidine kinase
C2U40_08215	ENOG4108V3W	Chemotaxis protein, CheW
C2U40_08220	ENOG4105C8Q	Methyl-accepting chemotaxis
C2U40_08225	ENOG4105CBS	Chea signal transduction histidine kinase
C2U40_08235	ENOG4108VYJ	response regulator receiver protein
C2U40_08240	ENOG4105E3S	small subunit
C2U40_08245	ENOG4105QA4	4Fe-4S Ferredoxin, iron-sulfur binding domain protein
C2U40_08250	ENOG4105CJ5	hydrogenase 2 b cytochrome subunit
C2U40_08255	ENOG4105DPX	Hydrogenase, large subunit
C2U40_08260	ENOG4108USZ	hydrogenase
C2U40_08265	ENOG4108WGS	hydrogenase 2-specific chaperone
C2U40_08275	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
C2U40_08280	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
C2U40_08285	ENOG4105C3U	ABC transporter
C2U40_08290	ENOG4105CDA	abc transporter atp-binding protein
C2U40_08295	ENOG4107RSS	Hydrogenase accessory protein HypB
C2U40_08300	ENOG4105WMM	Probably plays a role in a hydrogenase nickel cofactor insertion step (By similarity)
C2U40_08305	ENOG4105C45	hydrogenase expression formation protein (HypE)
C2U40_08310	ENOG4105CQS	hydrogenase expression formation protein HypD
C2U40_08315	ENOG4105WRB	Hydrogenase assembly chaperone hypC hupF
C2U40_08325	ENOG4105EM7	Selenocysteine-specific translation elongation factor
C2U40_08330	ENOG4105C1Y	Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis (By similarity)
C2U40_08335	ENOG4108MG9	hydrogenase 3 maturation protease
C2U40_08340	ENOG4105I6X	formate hydrogenlyase maturation
C2U40_08345	ENOG4105C47	NADH ubiquinone oxidoreductase 20 kda subunit
C2U40_08355	ENOG4105CQV	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
C2U40_08360	ENOG4107TDF	Formate hydrogenlyase subunit 4
C2U40_08365	ENOG4108JPZ	Monovalent cation H antiporter subunit D
C2U40_08370	ENOG4108MFN	small subunit of hydrogenase-3, iron-sulfur protein (part of formate hydrogenlyase (FHL) complex)
C2U40_08375	ENOG4105DFH	Transport of potassium into the cell (By similarity)
C2U40_08385	ENOG4108RC0	Electron transport protein
C2U40_08400	ENOG4108JUA	Transcriptional regulator
C2U40_08405	ENOG4107H9G	Necessary for formate dehydrogenase activity (By similarity)
C2U40_08410	ENOG4105F3K	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity)
C2U40_08420	ENOG4105CJX	Molecular chaperone. Has ATPase activity (By similarity)
C2U40_08430	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
C2U40_08435	ENOG4105CFX	Catalyzes the ferrous insertion into protoporphyrin IX (By similarity)
C2U40_08445	ENOG4107RE1	Inosine-guanosine kinase
C2U40_08460	ENOG4105BZU	Histidine kinase
C2U40_08475	ENOG4105F3T	(LipO)protein
C2U40_08485	ENOG4108IQC	2,3-dihydroxybenzoate-AMP ligase
C2U40_08490	ENOG4105WQI	isochorismatase
C2U40_08495	ENOG4105CEY	Amp-dependent synthetase and ligase
C2U40_08500	ENOG4105X17	23-dihydro-2,3-dihydroxybenzoate dehydrogenase
C2U40_08510	ENOG4105CEY	Amp-dependent synthetase and ligase
C2U40_08515	ENOG4108MES	Periplasmic binding protein
C2U40_08520	ENOG4108TSE	Transferase
C2U40_08525	ENOG4105E0A	ABC, transporter
C2U40_08530	ENOG4105TVJ	transport system, permease
C2U40_08535	ENOG4105DQ5	transport system permease protein
C2U40_08540	ENOG4105D05	Receptor
C2U40_08555	ENOG4105QZU	Inner membrane protein YfeZ
C2U40_08560	ENOG4107QUT	magnesium and cobalt transport protein CorA
C2U40_08565	ENOG4105DWH	electron transfer flavoprotein-ubiquinone oxidoreductase
C2U40_08570	ENOG4105BZJ	Electron transfer flavoprotein
C2U40_08575	ENOG4105C10	Electron transfer flavoprotein
C2U40_08580	ENOG4107QM1	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine (By similarity)
C2U40_08585	ENOG4105CMY	5-enolpyruvylshikimate-3-phosphate synthase
C2U40_08590	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
C2U40_08595	ENOG4108NVR	Methyl-accepting chemotaxis
C2U40_08600	ENOG4105D4P	Coproporphyrinogen iii oxidase
C2U40_08605	ENOG4105DVS	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
C2U40_08630	ENOG4105DFH	Transport of potassium into the cell (By similarity)
C2U40_08635	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
C2U40_08640	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
C2U40_08655	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
C2U40_08670	ENOG4105FQ6	thiopurine methyltransferase
C2U40_08675	ENOG4107VK2	coenzyme PQQ biosynthesis protein PqqF
C2U40_08680	ENOG4108BY2	phosphohistidine phosphatase
C2U40_08690	ENOG4108IPJ	Membrane
C2U40_08695	ENOG4108J59	Extracellular solute-binding protein, family 5
C2U40_08700	ENOG4105CZI	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
C2U40_08705	ENOG4108JA2	transcriptioN-repair coupling factor
C2U40_08715	ENOG4105D60	lipoprotein releasing system transmembrane protein
C2U40_08720	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
C2U40_08725	ENOG4105D60	lipoprotein releasing system transmembrane protein
C2U40_08745	ENOG4105DEA	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation
C2U40_08750	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
C2U40_08755	ENOG4105CHN	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
C2U40_08760	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
C2U40_08765	ENOG4105K70	DNA-binding protein
C2U40_08770	ENOG4105EIN	peptidylprolyl cis-trans isomerase
C2U40_08775	ENOG4105C5H	ABC transporter
C2U40_08780	ENOG4107QN1	sodium solute
C2U40_08785	ENOG41062QD	Membrane
C2U40_08800	ENOG41060WC	Enoyl-CoA hydratase
C2U40_08805	ENOG4105BZG	amino acid carrier protein
C2U40_08820	ENOG4106HK8	GPR1 FUN34 yaaH family protein
C2U40_08855	ENOG4107QX3	carboxylase
C2U40_08860	ENOG4105C1G	acyl-Coa dehydrogenase
C2U40_08865	ENOG4105C26	Dehydrogenase
C2U40_08870	ENOG4105C1G	acyl-Coa dehydrogenase
C2U40_08875	ENOG4105E39	Enoyl-CoA hydratase
C2U40_08880	ENOG4105E39	Enoyl-CoA hydratase
C2U40_08885	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
C2U40_08895	ENOG4105D5Q	Arginine ornithine antiporter
C2U40_08900	ENOG4105HF0	Membrane
C2U40_08940	ENOG4108KB2	LysR family Transcriptional regulator
C2U40_08945	ENOG4105CS2	ec 3.2.1.21
C2U40_08950	ENOG4105BZU	Histidine kinase
C2U40_08960	ENOG4105DHT	Metal Dependent Phosphohydrolase
C2U40_08965	ENOG4105CHR	reductase
C2U40_08970	ENOG4105CBN	LysR family transcriptional regulator
C2U40_08975	ENOG4105EFU	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin (By similarity)
C2U40_08985	ENOG4105DUM	transcriptional regulator, lysR family
C2U40_08995	ENOG4105NWR	lipid A biosynthesis (Kdo)2-(Lauroyl)-lipid IVA acyltransferase
C2U40_09000	ENOG4105NWR	lipid A biosynthesis (Kdo)2-(Lauroyl)-lipid IVA acyltransferase
C2U40_09025	ENOG4105CQ2	DNA polymerase
C2U40_09055	ENOG4107QI1	Mate efflux family protein
C2U40_09060	ENOG4105W1I	UPF0253 protein
C2U40_09065	ENOG4108R6K	riboflavin synthase, subunit alpha
C2U40_09075	ENOG4107UW8	HAD-superfamily hydrolase subfamily IA variant 3
C2U40_09080	ENOG4108HH9	Catalyzes two reactions the first one is the production of beta-formyl glycinamide ribonucleotide (GAR) from formate, ATP and beta GAR
C2U40_09085	ENOG4108SXK	Transporter Drug Metabolite Exporter family
C2U40_09090	ENOG4108V3G	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity)
C2U40_09125	ENOG4105XW2	UPF0263 protein
C2U40_09130	ENOG4108VKV	Monofunctional biosynthetic peptidoglycan transglycosylase
C2U40_09140	ENOG4105VJP	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell (By similarity)
C2U40_09145	ENOG4107QMS	site-determining protein
C2U40_09150	ENOG4105K7U	Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization (By similarity)
C2U40_09155	ENOG4105VNG	YcgL domain-containing protein
C2U40_09160	ENOG4105CVE	Lytic murein transglycosylase
C2U40_09165	ENOG4105EJQ	L-serine dehydratase
C2U40_09175	ENOG4105EJQ	L-serine dehydratase
C2U40_09180	ENOG4105NBK	UPF0345 protein
C2U40_09185	ENOG4105CK2	sodium dicarboxylate symporter
C2U40_09195	ENOG4105CHU	acetyl-coa acetyltransferase
C2U40_09200	ENOG4105D58	Diguanylate phosphodiesterase
C2U40_09205	ENOG4105CKF	membrane protein involved in aromatic hydrocarbon degradation
C2U40_09210	ENOG4105CKF	membrane protein involved in aromatic hydrocarbon degradation
C2U40_09220	ENOG4105EMN	RNA polymerase sigma factor
C2U40_09250	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
C2U40_09255	ENOG4105CHU	acetyl-coa acetyltransferase
C2U40_09260	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
C2U40_09270	ENOG4108VWS	Yaeq family
C2U40_09300	ENOG4108JUB	Transcriptional regulator
C2U40_09305	ENOG4105IW6	Carbamoyltransferase
C2U40_09310	ENOG4107RCH	Diaminopropionate ammonia-lyase
C2U40_09315	ENOG4107S4Y	M20 DapE family protein YgeY
C2U40_09320	ENOG4105CD3	dihydroorotase
C2U40_09325	ENOG4105C5B	carbamate kinase
C2U40_09330	ENOG4108Q5Y	Membrane
C2U40_09335	ENOG4107P0T	Selenium-dependent molybdenum hydroxylase system protein, YqeB family
C2U40_09340	ENOG4105MJ6	selenium-dependent hydroxylase accessory protein YqeC
C2U40_09345	ENOG4105MFX	4-diphosphocytidyl-2c-methyl-d-erythritol synthase
C2U40_09410	ENOG4108XFH	Transcriptional regulator
C2U40_09415	ENOG4105F6U	Short-chain dehydrogenase reductase Sdr
C2U40_09430	ENOG4107QXP	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
C2U40_09455	ENOG4105CHU	acetyl-coa acetyltransferase
C2U40_09520	ENOG4105CYM	Glutathione S-transferase
C2U40_09525	ENOG4107RFB	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
C2U40_09535	ENOG4105F04	LysR family Transcriptional regulator
C2U40_09545	ENOG4107QXP	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
C2U40_09560	ENOG4105E66	phosphoriboisomerase A
C2U40_09580	ENOG41067TZ	transcriptional regulator, MarR family
C2U40_09585	ENOG4105DUM	transcriptional regulator, lysR family
C2U40_09660	ENOG4105E4C	Lytic transglycosylase catalytic
C2U40_09680	ENOG4107RHT	methyl-accepting chemotaxis sensory transducer with Pas Pac sensor
C2U40_09705	ENOG4107UUR	Chlorohydrolase aminohydrolase
C2U40_09710	ENOG410873Y	FAD binding domain in molybdopterin dehydrogenase
C2U40_09715	ENOG4105C7W	Xanthine dehydrogenase
C2U40_09720	ENOG4105C2W	permease
C2U40_09725	ENOG4107QUY	Guanine deaminase
C2U40_09730	ENOG4105C7N	Xanthine uracil vitamin C permease
C2U40_09735	ENOG4105C7W	Xanthine dehydrogenase
C2U40_09740	ENOG4108HR6	Dehydrogenase
C2U40_09745	ENOG4108UTP	(2Fe-2S)-binding domain protein
C2U40_09755	ENOG4107MBR	17 kDa surface antigen
C2U40_09765	ENOG4105CSX	c4-dicarboxylate anaerobic carrier
C2U40_09770	ENOG4105CEY	Amp-dependent synthetase and ligase
C2U40_09775	ENOG4105K8F	Phosphoribosyl-amp cyclohydrolase
C2U40_09780	ENOG4105C0S	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity)
C2U40_09785	ENOG4105BZU	Histidine kinase
C2U40_09795	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
C2U40_09800	ENOG4105CJV	Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase
C2U40_09805	ENOG4108UJE	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity)
C2U40_09810	ENOG4105ECC	imidazole-glycerol-phosphate dehydratase
C2U40_09815	ENOG4105CIH	Imidazole acetol-phosphate transaminase
C2U40_09820	ENOG4105CEK	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity)
C2U40_09825	ENOG4105E21	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity)
C2U40_09835	ENOG4105DVT	helicase
C2U40_09845	ENOG41072GX	Peptidase M22 Glycoprotease
C2U40_09855	ENOG410626R	Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity)
C2U40_09860	ENOG4105CEY	Amp-dependent synthetase and ligase
C2U40_09865	ENOG4105ZIE	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides (By similarity)
C2U40_09870	ENOG4106PMH	Extracellular solute-binding protein family 3
C2U40_09880	ENOG4105FBT	Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs (By similarity)
C2U40_09885	ENOG4105WD1	Membrane
C2U40_09890	ENOG4109003	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity)
C2U40_09895	ENOG4107QMP	dna polymerase iii subunits gamma and tau
C2U40_09900	ENOG4105KDX	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection (By similarity)
C2U40_09920	ENOG4105CQ7	ATP-dependent helicase
C2U40_09930	ENOG4105KW6	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance (By similarity)
C2U40_09935	ENOG4105BZU	Histidine kinase
C2U40_09940	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
C2U40_09945	ENOG4105C5X	domain protein
C2U40_09950	ENOG4105CR7	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA (By similarity)
C2U40_09955	ENOG4105D4F	Synthesizes selenophosphate from selenide and ATP (By similarity)
C2U40_09960	ENOG4105FAT	Acyl-transferase
C2U40_09970	ENOG4105DR4	Methyltransferase
C2U40_09980	ENOG4108N3W	hemolysin secretion protein
C2U40_09985	ENOG4105VSY	K01512 acylphosphatase EC 3.6.1.7
C2U40_09990	ENOG4108K3A	Glutathione S-transferase
C2U40_09995	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
C2U40_10000	ENOG4105D1F	ATP-binding protein
C2U40_10005	ENOG4105DBI	uridine monophosphokinase
C2U40_10010	ENOG4105DHP	deoxycytidine triphosphate deaminase
C2U40_10015	ENOG4105CJ3	phosphate transporter
C2U40_10025	ENOG4105C03	ribonuclease
C2U40_10030	ENOG4105EI2	Pseudouridine synthase
C2U40_10035	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
C2U40_10040	ENOG4108UHJ	MAF-like protein
C2U40_10045	ENOG4105CNH	Multidrug resistance protein MdtL
C2U40_10060	ENOG4105FCQ	metal-binding, possibly nucleic acid-binding protein
C2U40_10065	ENOG4105VGS	50s ribosomal protein l32
C2U40_10070	ENOG4105C6B	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA (By similarity)
C2U40_10075	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
C2U40_10080	ENOG4105CJF	Malonyl coA-acyl carrier protein transacylase
C2U40_10085	ENOG4105CHR	reductase
C2U40_10090	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
C2U40_10095	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
C2U40_10100	ENOG4105YAZ	4-amino-4-deoxychorismate lyase
C2U40_10105	ENOG4105HHA	aminodeoxychorismate lyase
C2U40_10110	ENOG4108ZMD	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity)
C2U40_10115	ENOG4107QRG	dna polymerase iii
C2U40_10120	ENOG4105F8V	Hydrolase, tatD family
C2U40_10140	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
C2U40_10145	ENOG4105DY2	Paraquat-inducible protein b
C2U40_10150	ENOG4105F1S	paraquat-inducible protein a
C2U40_10160	ENOG4105CR4	methylisocitrate lyase
C2U40_10165	ENOG4105BZN	citrate synthase
C2U40_10170	ENOG4105DXD	2-methylcitrate dehydratase
C2U40_10210	ENOG4105PDP	Short chain dehydrogenase
C2U40_10220	ENOG4105X2V	dna damage-inducible protein
C2U40_10230	ENOG4105DAN	ATP-dependent protease
C2U40_10235	ENOG4108RKI	Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl- ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)- decenoyl-ACP. Can catalyze the dehydratase reaction for beta- hydroxyacyl-ACPs with saturated chain lengths up to 16 0, being most active on intermediate chain length (By similarity)
C2U40_10240	ENOG4105WFT	During stationary phase, converts 70S ribosomes to an inactive dimeric form (100S ribosomes) (By similarity)
C2U40_10250	ENOG4105C5H	ABC transporter
C2U40_10260	ENOG4105C4H	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA (By similarity)
C2U40_10265	ENOG4108T7E	Contributes to the efficiency of the cell division process by stabilizing the polymeric form of the cell division protein FtsZ. Acts by promoting interactions between FtsZ protofilaments and suppressing the GTPase activity of FtsZ (By similarity)
C2U40_10270	ENOG4107QYT	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor (By similarity)
C2U40_10275	ENOG4105C7I	Dehydrogenase
C2U40_10285	ENOG4105CD8	aminopeptidase N
C2U40_10290	ENOG4105CN1	protease
C2U40_10295	ENOG41073DY	may be a structural element that influences the osmotic activation of ProP at a post-translational level (By similarity)
C2U40_10300	ENOG4108ZGC	gaf domain protein
C2U40_10310	ENOG4105EUH	cytochrome C oxidase, cbb3-type, subunit i
C2U40_10325	ENOG4105D6P	C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex (By similarity)
C2U40_10350	ENOG4105DS0	Transcriptional regulator, Crp Fnr family
C2U40_10355	ENOG4105Q9Y	Universal stress protein
C2U40_10360	ENOG4105CB3	Required for the thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32) (By similarity)
C2U40_10375	ENOG4108K3A	Glutathione S-transferase
C2U40_10380	ENOG4105MRB	Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose (By similarity)
C2U40_10385	ENOG4105C2J	ABC transporter
C2U40_10390	ENOG4105CNN	ABC, transporter
C2U40_10395	ENOG4105E9V	Periplasmic binding protein LacI transcriptional regulator
C2U40_10400	ENOG4108RVA	ribokinase
C2U40_10405	ENOG4105ETE	Transcriptional regulator (LacI family
C2U40_10410	ENOG4105BZU	Histidine kinase
C2U40_10420	ENOG4105NDF	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity)
C2U40_10435	ENOG4105BZU	Histidine kinase
C2U40_10440	ENOG4108ZUF	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
C2U40_10445	ENOG4105C6A	phenylalanyl-tRNA synthetase (beta subunit)
C2U40_10450	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
C2U40_10455	ENOG4108YZX	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity)
C2U40_10460	ENOG41083UC	50s ribosomal protein L35
C2U40_10465	ENOG4108UUX	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity)
C2U40_10470	ENOG4105C22	threonyL-tRNA synthetase
C2U40_10485	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
C2U40_10490	ENOG4108HWB	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
C2U40_10495	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
C2U40_10500	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
C2U40_10505	ENOG4105E05	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
C2U40_10510	ENOG4105XPH	Ferredoxin
C2U40_10515	ENOG4105CA3	membrane-bound lytic murein transglycosylase
C2U40_10520	ENOG4105XZD	Fe-S protein
C2U40_10525	ENOG4107SZR	mannose-6-phosphate isomerase
C2U40_10530	ENOG4105F3R	pts system mannose fructose sorbose family iid
C2U40_10535	ENOG4105ETZ	PTS System
C2U40_10540	ENOG4108EQA	pts system
C2U40_10555	ENOG4107P2S	Transcriptional regulator
C2U40_10560	ENOG4108Y83	glucose-6-phosphate isomerase
C2U40_10565	ENOG4105DM4	PTS System
C2U40_10570	ENOG4105DE4	1-phosphofructokinase
C2U40_10575	ENOG4105DTZ	bifunctional PTS system fructose-specific transporter subunit IIA HPr protein
C2U40_10580	ENOG4107B7Y	DNA-binding transcriptional regulator FruR
C2U40_10585	ENOG4105E0U	tyrosine-specific transport protein
C2U40_10600	ENOG4105C1J	atp-dependent rna helicase
C2U40_10610	ENOG4105D10	5-enolpyruvylshikimate-3-phosphate phospholyase
C2U40_10615	ENOG4105C76	Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue (By similarity)
C2U40_10620	ENOG4108DG9	Smr protein MutS2
C2U40_10630	ENOG4105BZU	Histidine kinase
C2U40_10635	ENOG4105DKJ	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
C2U40_10660	ENOG4108Z8G	Alkylphosphonate utilization operon protein PhnA
C2U40_10730	ENOG4105DUC	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division (By similarity)
C2U40_10735	ENOG4105DAH	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF (By similarity)
C2U40_10740	ENOG4105GHU	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid partitioning. Probably acts via its interaction with MukB and MukE. Overexpression results in anucleate cells. It has a calcium binding activity (By similarity)
C2U40_10745	ENOG4106371	Methyltransferase
C2U40_10750	ENOG4107S90	membrAne
C2U40_10760	ENOG4105CTQ	phosphohexokinase
C2U40_10765	ENOG4105CH2	amidohydrolase
C2U40_10770	ENOG4105PAD	Hydrolase
C2U40_10775	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
C2U40_10830	ENOG4105CPB	ATP-dependent endonuclease of the OLD family
C2U40_10845	ENOG4105VP0	transcriptional regulator, lysR family
C2U40_10850	ENOG4105EJ9	Membrane
C2U40_10855	ENOG4106IUH	DTW domain containing protein
C2U40_10865	ENOG4105CPF	Cell wall formation (By similarity)
C2U40_10880	ENOG4108V06	Glutathione peroxidase
C2U40_10885	ENOG4105C1J	atp-dependent rna helicase
C2U40_10890	ENOG4105K5X	acetyltransferase
C2U40_10900	ENOG4105KK4	UPF0060 membrane protein
C2U40_10930	ENOG41061CK	Antibiotic biosynthesis monooxygenase
C2U40_10935	ENOG4107XGF	functions in a salvage pathway. Uses pyridoxamine (By similarity)
C2U40_10960	ENOG4105D1N	poly(r)-hydroxyalkanoic acid synthase, class
C2U40_10970	ENOG4105WQ3	Rna-binding protein
C2U40_10980	ENOG4105BZ1	(ABC) transporter
C2U40_10990	ENOG4105BZ1	(ABC) transporter
C2U40_10995	ENOG4105BZU	Histidine kinase
C2U40_11000	ENOG4105K63	Thioredoxin
C2U40_11005	ENOG4105C8P	)-transporter
C2U40_11010	ENOG4107QQN	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties (By similarity)
C2U40_11035	ENOG4105CRQ	synthase (Component I)
C2U40_11045	ENOG4105C44	Serine transporter
C2U40_11050	ENOG4107QV7	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system) (By similarity)
C2U40_11055	ENOG4105C9U	ATP-dependent DNA helicase RecQ
C2U40_11060	ENOG4105CYN	Serine protein kinase
C2U40_11070	ENOG4105ED1	spovr family
C2U40_11075	ENOG4105C05	Multifunctional regulator of fatty acid metabolism (By similarity)
C2U40_11080	ENOG4105DKR	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity)
C2U40_11085	ENOG410635M	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein (By similarity)
C2U40_11090	ENOG4105DQR	SNARE associated Golgi
C2U40_11100	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
C2U40_11115	ENOG4105D0C	transport protein
C2U40_11120	ENOG4105CHQ	Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella (By similarity)
C2U40_11140	ENOG4108MRH	transcriptional regulatory protein
C2U40_11145	ENOG4105CEQ	signal transduction histidine kinase regulating citrate malate metabolism
C2U40_11150	ENOG4105E2R	ROK family
C2U40_11155	ENOG4105C8Q	Methyl-accepting chemotaxis
C2U40_11160	ENOG4105K5B	UPF0225 protein
C2U40_11165	ENOG4107R5Y	anaerobic glycerol-3-phosphate dehydrogenase, subunit A
C2U40_11170	ENOG4108KJ0	anaerobic glycerol-3-phosphate dehydrogenase, subunit B
C2U40_11175	ENOG4105CHG	glycolate oxidase (iron-sulfur subunit)
C2U40_11185	ENOG4105JJ8	Cytochrome c nitrite reductase, pentaheme subunit
C2U40_11190	ENOG4105D3S	4Fe-4S Ferredoxin, iron-sulfur binding domain protein
C2U40_11195	ENOG4105DVI	reductase, NrfD
C2U40_11200	ENOG4105DA4	cytochrome c-type biogenesis protein
C2U40_11205	ENOG4107QX9	Thiol disulfide interChange protein
C2U40_11210	ENOG4108DMF	Cytochrome C biogenesis protein
C2U40_11220	ENOG41061WM	D-Alanyl-D-Alanine
C2U40_11225	ENOG4105C0F	tryptophanase EC 4.1.99.1
C2U40_11235	ENOG4105EXX	Deoxyribodipyrimidine photolyase-related protein
C2U40_11240	ENOG4105MWK	D-amino acid dehydrogenase, small subunit
C2U40_11255	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
C2U40_11265	ENOG4105DSS	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation (By similarity)
C2U40_11270	ENOG4105DZ2	Transcriptional regulator
C2U40_11280	ENOG4105E0K	tonB-dependent siderophore receptor
C2U40_11285	ENOG4108XW0	May be a transcriptional activator of genes involved in the multiple antibiotic resistance (Mar) phenotype. It can also activate genes such as sodA, zwf and micF
C2U40_11295	ENOG4105CR8	Transcriptional regulator
C2U40_11300	ENOG4108RYK	Nad-dependent epimerase dehydratase
C2U40_11320	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
C2U40_11325	ENOG4105KPY	Small multidrug resistance protein
C2U40_11330	ENOG4105DDY	UPF0142 protein ycaO
C2U40_11335	ENOG4105TMB	Formate nitrite transporter
C2U40_11340	ENOG4105C6N	Formate acetyltransferase
C2U40_11345	ENOG4108KAZ	Involved in phosphonate degradation (By similarity)
C2U40_11350	ENOG4108JPW	Aminotransferase
C2U40_11355	ENOG4107STF	Involved in phosphonate degradation (By similarity)
C2U40_11365	ENOG4105C4Y	ABC transporter
C2U40_11375	ENOG4107RCV	ABC transporter, permease
C2U40_11380	ENOG4105CJP	fad dependent oxidoreductase
C2U40_11390	ENOG4105CH8	Succinyl-CoA ligase ADP-forming subunit alpha
C2U40_11395	ENOG4105CMV	Succinyl-CoA synthetase subunit beta
C2U40_11400	ENOG4105C7S	Dehydrogenase
C2U40_11405	ENOG4105C7P	2-oxoglutarate dehydrogenase, E1
C2U40_11410	ENOG4105E33	succinate dehydrogenase
C2U40_11415	ENOG4105C00	Succinate dehydrogenase (Flavoprotein subunit)
C2U40_11420	ENOG4105N1I	succinate dehydrogenase, hydrophobic membrane anchor protein
C2U40_11425	ENOG4108UTY	succinate dehydrogenase, cytochrome b556 subunit
C2U40_11430	ENOG4105BZN	citrate synthase
C2U40_11445	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
C2U40_11450	ENOG4105CWG	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34 (By similarity)
C2U40_11460	ENOG4105CEE	C4-dicarboxylate transporter
C2U40_11475	ENOG4108VKG	metal-dependent hydrolase
C2U40_11490	ENOG4105NRA	50s ribosomal protein l31 type b
C2U40_11500	ENOG4105EUB	pirin domain protein
C2U40_11505	ENOG4105HEI	LysR family (Transcriptional regulator
C2U40_11515	ENOG4105CNN	ABC, transporter
C2U40_11525	ENOG4105DMK	Periplasmic binding protein LacI transcriptional regulator
C2U40_11530	ENOG4105EF1	ribulokinase
C2U40_11540	ENOG4105CAC	Catalyzes the conversion of L-arabinose to L-ribulose (By similarity)
C2U40_11545	ENOG4105CJB	Exodeoxyribonuclease I
C2U40_11555	ENOG4107R49	K07407 alpha-galactosidase EC 3.2.1.22
C2U40_11565	ENOG41067MG	lrgb family
C2U40_11570	ENOG4107T42	This enzyme scavenge exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis (By similarity)
C2U40_11575	ENOG4108IQE	Amp-dependent synthetase and ligase
C2U40_11580	ENOG4105MH2	YfcL protein
C2U40_11590	ENOG4105EE5	Membrane protein terC
C2U40_11595	ENOG41090EK	ompa motb domain protein
C2U40_11600	ENOG4108KHX	Diguanylate cyclase
C2U40_11605	ENOG4108WS1	
C2U40_11620	ENOG41090A4	Pterin carbinolamine dehydratase
C2U40_11625	ENOG4105MIR	Phenylalanine 4-monooxygenase
C2U40_11630	ENOG4106K28	UPF0283 membrane protein
C2U40_11635	ENOG4105CM6	amino acid regulated cytosolic protein
C2U40_11645	ENOG4105YYT	phage shock protein B
C2U40_11650	ENOG41087YS	Phage shock protein A
C2U40_11655	ENOG4105E51	psp operon transcriptional activator
C2U40_11660	ENOG4108J59	Extracellular solute-binding protein, family 5
C2U40_11665	ENOG4108I5W	peptide transport system, permease protein
C2U40_11670	ENOG4108EU3	peptide transport system, permease
C2U40_11675	ENOG4108JQ3	Peptide ABC transporter ATP-binding protein
C2U40_11680	ENOG4108JQ2	peptide transport system atp-binding protein
C2U40_11685	ENOG4105FR9	TRNA-(Ms 2 io 6 A)-hydroxylase
C2U40_11690	ENOG4105CBA	glutamine phosphoribosylpyrophosphate amidotransferase
C2U40_11695	ENOG4105E96	Colicin v production protein
C2U40_11700	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
C2U40_11710	ENOG4105D1H	recombination factor protein RarA
C2U40_11715	ENOG4107Y7W	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) (By similarity)
C2U40_11720	ENOG4105CNU	cell division protein FtsK
C2U40_11725	ENOG4105EW9	transcriptional regulator AsnC family
C2U40_11730	ENOG4105DCF	alanine dehydrogenase
C2U40_11735	ENOG4105C3M	thioredoxin reductase
C2U40_11745	ENOG4105BZU	Histidine kinase
C2U40_11750	ENOG4107MBR	17 kDa surface antigen
C2U40_11755	ENOG4108R4Z	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine (By similarity)
C2U40_11760	ENOG4105DWA	May conjugate Arg from its aminoacyl-tRNA to the N- termini of proteins containing an N-terminal aspartate or glutamate
C2U40_11765	ENOG4105K9U	however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity)
C2U40_11770	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
C2U40_11775	ENOG4105KAE	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation (By similarity)
C2U40_11780	ENOG4105VEQ	Cold shock protein
C2U40_11785	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
C2U40_11815	ENOG4105CS6	Rhs element vgr protein
C2U40_11850	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
C2U40_11910	ENOG4105CNA	YD repeat protein
C2U40_11920	ENOG4105CS6	Rhs element vgr protein
C2U40_11925	ENOG4108WC9	type VI secretion system effector, hcp1 family
C2U40_11940	ENOG4108RMJ	sensory transduction regulator
C2U40_11950	ENOG4107104	thymidine kinase
C2U40_11955	ENOG4107S6Z	Na H antiporter
C2U40_11965	ENOG4108WBT	adenosyltransferase
C2U40_11970	ENOG4105VRT	cytoplasmic protein
C2U40_11975	ENOG4105EIZ	Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity)
C2U40_11980	ENOG4105FD2	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) (By similarity)
C2U40_11995	ENOG4106EG9	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) (By similarity)
C2U40_12000	ENOG4105CFV	Tetratricopeptide repeat protein
C2U40_12010	ENOG41080YA	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
C2U40_12015	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
C2U40_12020	ENOG4105CAT	Cytidine monophosphate kinase
C2U40_12025	ENOG4108JEN	Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate (By similarity)
C2U40_12030	ENOG4107R11	Transcriptional regulator
C2U40_12035	ENOG4105CMU	LysR family (Transcriptional regulator
C2U40_12040	ENOG4105D2S	major facilitator superfamily
C2U40_12055	ENOG4108DBC	nitroreductase
C2U40_12060	ENOG4105BZU	Histidine kinase
C2U40_12070	ENOG4105CBN	LysR family transcriptional regulator
C2U40_12075	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
C2U40_12100	ENOG4107RGM	aldo keto reductase
C2U40_12105	ENOG4105VFU	Rna-binding protein
C2U40_12115	ENOG4105HPZ	Involved in the removal of murein from the sacculus. May also facilitate integration of nascent murein strands into the sacculus by cleaving the peptide bonds between neighboring strands in mature murein (By similarity)
C2U40_12125	ENOG4105HA9	of methanol dehydrogenase type
C2U40_12140	ENOG4105E14	MotA TolQ exbB proton channel
C2U40_12145	ENOG4105ER2	Ompa motb domain protein
C2U40_12150	ENOG4105KWU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
C2U40_12155	ENOG4105ES3	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
C2U40_12160	ENOG4105CQV	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
C2U40_12165	ENOG4105GKE	subunit e
C2U40_12170	ENOG4107QIZ	NADH dehydrogenase
C2U40_12175	ENOG4108IEH	NADH dehydrogenase subunit g
C2U40_12180	ENOG4105CMZ	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone (By similarity)
C2U40_12185	ENOG4105P3U	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
C2U40_12190	ENOG4107UFS	subunit j
C2U40_12195	ENOG41080EA	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
C2U40_12200	ENOG4105D65	subunit l
C2U40_12205	ENOG4105C8S	subunit m
C2U40_12210	ENOG4105CNR	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
C2U40_12220	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
C2U40_12225	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
C2U40_12230	ENOG4107QIK	phosphoribosylformylglycinamidine synthase
C2U40_12235	ENOG4105CHQ	Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella (By similarity)
C2U40_12245	ENOG4105VPD	cellular component movement
C2U40_12255	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
C2U40_12260	ENOG4105CNE	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
C2U40_12265	ENOG4105N21	Membrane
C2U40_12270	ENOG4105CUT	histidyl-tRNA synthetase
C2U40_12275	ENOG4105C4E	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (By similarity)
C2U40_12280	ENOG4105HSZ	Cytoskeletal protein that is involved in cell-shape control through regulation of the length of the long axis (By similarity)
C2U40_12290	ENOG4105C55	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
C2U40_12295	ENOG4108UGX	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity)
C2U40_12310	ENOG4108ZIT	Ferredoxin, 2FE-2S
C2U40_12315	ENOG4105C9I	Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB
C2U40_12320	ENOG4108SWN	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA (By similarity)
C2U40_12325	ENOG4108Z4V	iron-sulfur cluster assembly
C2U40_12330	ENOG4107XTC	May be involved in the formation or repair of Fe-S clusters present in iron-sulfur proteins
C2U40_12335	ENOG4105C3J	Cysteine desulfurase
C2U40_12355	ENOG4105XPQ	lipid carrier protein
C2U40_12360	ENOG4105CFP	Peptidase U32
C2U40_12365	ENOG4106RZ4	Peptidase U32
C2U40_12380	ENOG4107RAB	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
C2U40_12385	ENOG4107QN8	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
C2U40_12390	ENOG4105VIE	preprotein translocase, subunit YajC
C2U40_12395	ENOG4105C6U	Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity)
C2U40_12400	ENOG4105E2N	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) (By similarity)
C2U40_12405	ENOG4105W87	Cbs domain
C2U40_12410	ENOG4105D3R	alkyl hydroperoxide reductase
C2U40_12435	ENOG4105K89	arsenate reductase
C2U40_12440	ENOG4105D6J	arsenicaL-resistance protein
C2U40_12455	ENOG41085FC	arsR family transcriptional regulator
C2U40_12470	ENOG4105CBI	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
C2U40_12475	ENOG4105KE9	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity)
C2U40_12480	ENOG4105D43	The glycine cleavage system catalyzes the degradation of glycine (By similarity)
C2U40_12485	ENOG4105EAK	ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family
C2U40_12490	ENOG4105D0A	hydroxylase
C2U40_12500	ENOG4107YUN	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division (By similarity)
C2U40_12510	ENOG4105E5M	Multidrug resistance protein D
C2U40_12515	ENOG4105CYM	Glutathione S-transferase
C2U40_12575	ENOG4105DUF	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively (By similarity)
C2U40_12600	ENOG4105MQ3	flagellar protein FliS
C2U40_12615	ENOG4105I03	Flagellin
C2U40_12620	ENOG4105I03	Flagellin
C2U40_12630	ENOG4105EN6	Membrane
C2U40_12640	ENOG4105D8I	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS (By similarity)
C2U40_12660	ENOG410682P	Hypothetical protein (DUF2513)
C2U40_12730	ENOG4108JQB	penicillin-binding protein 1C
C2U40_12735	ENOG4105DN3	alpha-2-macroglobulin domain protein
C2U40_12740	ENOG4107QMW	pyridine nucleotide-disulfide oxidoreductase
C2U40_12745	ENOG4105BZU	Histidine kinase
C2U40_12750	ENOG4105F1A	Pyruvate formate-lyase
C2U40_12765	ENOG4105DSP	amino acid AbC transporter
C2U40_12770	ENOG4106PMH	Extracellular solute-binding protein family 3
C2U40_12775	ENOG4108JEH	abc transporter atp-binding protein
C2U40_12780	ENOG4105DWU	Membrane
C2U40_12785	ENOG4105DYB	Isoaspartyl dipeptidase
C2U40_12790	ENOG4108ZYK	Acyl carrier protein phosphodiesterase
C2U40_12805	ENOG4105K89	arsenate reductase
C2U40_12815	ENOG4105ERG	peptidase m48, ste24p
C2U40_12820	ENOG41082K8	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Interacts with IscS and stimulates its activity. Then, accepts a sulfur from IscS and transfers it in turn to TusD (By similarity)
C2U40_12840	ENOG4105CSR	polyphosphate kinase 2
C2U40_12845	ENOG4108IJ9	(ABC) transporter
C2U40_12850	ENOG4105EG2	ABC transporter, permease
C2U40_12855	ENOG4105D56	permease protein
C2U40_12860	ENOG4107FKK	extracellular solute-binding protein family 1
C2U40_12865	ENOG4106V8H	Nucleoid-associated protein
C2U40_12870	ENOG4105PAN	UPF0352 protein
C2U40_12875	ENOG4105E68	Sulfatase
C2U40_12880	ENOG4105D05	Receptor
C2U40_12885	ENOG4105CUG	Oligopeptidase b
C2U40_12905	ENOG4108QSZ	General inhibitor of pancreatic serine proteases inhibits chymotrypsin, trypsin, elastases, factor X, kallikrein as well as a variety of other proteases (By similarity)
C2U40_12910	ENOG4108WFC	UPF0438 protein yifE
C2U40_12915	ENOG4105CVI	Transcriptional regulator
C2U40_12925	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
C2U40_12930	ENOG4106MZZ	glycerophosphoryl diester phosphodiesterase
C2U40_12935	ENOG4105C6V	Glycerol-3-phosphate dehydrogenase
C2U40_12945	ENOG4105E98	transcriptional regulator DeoR family
C2U40_12950	ENOG4105CXY	transporter
C2U40_12955	ENOG4105D8C	Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity)
C2U40_12960	ENOG4108JQ0	Key enzyme in the regulation of glycerol uptake and metabolism (By similarity)
C2U40_12965	ENOG4105HEI	LysR family (Transcriptional regulator
C2U40_12990	ENOG4105CV8	reductase
C2U40_12995	ENOG4105F27	Major Facilitator
C2U40_13005	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
C2U40_13010	ENOG4105C4M	(Ubiquinol oxidase) subunit I
C2U40_13015	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
C2U40_13020	ENOG4108Q2J	Inner membrane protein YebE
C2U40_13035	ENOG4106428	Protein of unknown function (DUF2496)
C2U40_13045	ENOG4105D2S	major facilitator superfamily
C2U40_13060	ENOG4105DJ2	Major Facilitator Superfamily
C2U40_13065	ENOG4105FE9	pseudouridine synthase
C2U40_13075	ENOG4105D82	Glutamate dehydrogenase
C2U40_13085	ENOG4105I9P	Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor (By similarity)
C2U40_13095	ENOG4108R4U	Hnh endonuclease
C2U40_13110	ENOG4105CEM	UPF0597 protein
C2U40_13115	ENOG4105KME	endoribonuclease L-psp
C2U40_13120	ENOG4105C44	Serine transporter
C2U40_13125	ENOG4108NVR	Methyl-accepting chemotaxis
C2U40_13140	ENOG4105DP5	Catalyzes the biosynthesis of agmatine from arginine (By similarity)
C2U40_13160	ENOG4105D42	Cleaves the N-terminal amino acid of tripeptides (By similarity)
C2U40_13185	ENOG4108YYC	ycei family
C2U40_13190	ENOG4105CC0	LysR family Transcriptional regulator
C2U40_13200	ENOG4105CKU	formyltetrahydrofolate synthetase
C2U40_13205	ENOG4105CKU	formyltetrahydrofolate synthetase
C2U40_13210	ENOG4105C8Q	Methyl-accepting chemotaxis
C2U40_13215	ENOG4105EUJ	GTP cyclohydrolase i
C2U40_13220	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
C2U40_13225	ENOG4105D06	uba thif-type nad fad binding protein
C2U40_13230	ENOG4105CGF	Aromatic amino acid aminotransferase
C2U40_13255	ENOG4105DVT	helicase
C2U40_13265	ENOG4105DGU	Histone deacetylase
C2U40_13270	ENOG4108ISG	Major Facilitator
C2U40_13275	ENOG4105C9W	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity (By similarity)
C2U40_13300	ENOG4105NXH	GreA GreB family elongation factor
C2U40_13305	ENOG4108KX4	response regulator
C2U40_13310	ENOG4105BZU	Histidine kinase
C2U40_13315	ENOG4105CXY	transporter
C2U40_13320	ENOG4105BZU	Histidine kinase
C2U40_13325	ENOG4106TNF	Periplasmic binding protein
C2U40_13330	ENOG4105E5Q	amino acid AbC transporter
C2U40_13335	ENOG4105CDA	abc transporter atp-binding protein
C2U40_13350	ENOG4105D5Q	Arginine ornithine antiporter
C2U40_13365	ENOG4105C37	(CBS) domain
C2U40_13375	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
C2U40_13380	ENOG4105E2Z	phosphate ABC transporter (Permease
C2U40_13385	ENOG4105C8U	phosphate abc transporter
C2U40_13390	ENOG4108Z6B	deaminase
C2U40_13400	ENOG4107QP3	malate synthase g
C2U40_13405	ENOG4108I9X	Isocitrate lyase
C2U40_13420	ENOG4105CZ5	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate (By similarity)
C2U40_13425	ENOG4105CXB	phosphoribosylaminoimidazole synthetase
C2U40_13430	ENOG4108V3E	phosphoribosylglycinamide formyltransferase
C2U40_13435	ENOG4107QNR	UPF0135 protein
C2U40_13440	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
C2U40_13445	ENOG4105BZU	Histidine kinase
C2U40_13450	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
C2U40_13460	ENOG4105RH4	Glycine cleavage system transcriptional repressor
C2U40_13465	ENOG4105CUU	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) (By similarity)
C2U40_13470	ENOG4105C9X	ppx gppa phosphatase
C2U40_13480	ENOG4108JDX	DNA polymerase iii, epsilon subunit
C2U40_13485	ENOG4108UMW	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
C2U40_13490	ENOG4105D1A	Methyltransferase
C2U40_13495	ENOG4108RW0	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
C2U40_13500	ENOG4105E9H	Lytic Murein transglycosylase
C2U40_13505	ENOG4105VNT	transposase (IS4 family) protein
C2U40_13520	ENOG4105NAU	thioesterase Superfamily protein
C2U40_13530	ENOG41060NJ	transcriptional regulator
C2U40_13535	ENOG4107SC1	transglycosylase
C2U40_13540	ENOG4105BZU	Histidine kinase
C2U40_13545	ENOG4108WPH	sigma 54 modulation protein ribosomal protein S30EA
C2U40_13565	ENOG4105MA0	exported protein
C2U40_13570	ENOG4105CFU	surface antigen
C2U40_13580	ENOG4107UUG	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity)
C2U40_13595	ENOG4107ZN8	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity (By similarity)
C2U40_13605	ENOG4105VNH	ABC transporter solute-binding protein
C2U40_13615	ENOG4108VGW	abc transporter atp-binding protein
C2U40_13620	ENOG4108T9J	Cdp-alcohol phosphatidyltransferase
C2U40_13625	ENOG4105CVE	Lytic murein transglycosylase
C2U40_13650	ENOG4107QIX	Phosphoglucomutase (EC 5.4.2.2
C2U40_13655	ENOG4107CDU	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated (By similarity)
C2U40_13660	ENOG4105EV9	Alpha Beta Hydrolase
C2U40_13670	ENOG4105NNH	LexA regulated protein
C2U40_13675	ENOG4105MHQ	Low-potential electron donor to a number of redox enzymes (By similarity)
C2U40_13685	ENOG41090R7	Ferric uptake
C2U40_13690	ENOG4105CX6	glutaminyL-tRNA synthetase
C2U40_13695	ENOG4105E2D	ec 3.2.1.52
C2U40_13700	ENOG4105CI1	PTS System
C2U40_13705	ENOG4105CKA	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion (By similarity)
C2U40_13710	ENOG4105CE4	GlcNAc 6-P deacetylase
C2U40_13715	ENOG4105E2R	ROK family
C2U40_13720	ENOG4105DIJ	Phosphoethanolamine transferase
C2U40_13725	ENOG4105CDY	transcriptional regulatory protein
C2U40_13730	ENOG4105C9M	aspartyl-trna synthetase
C2U40_13735	ENOG41081XQ	Conserved Protein
C2U40_13740	ENOG4105DA6	Catalyzes the conversion of 5-methoxyuridine (mo5U) to uridine-5-oxyacetic acid (cmo5U) at position 34 in tRNA. May also participate in the methylation of uridine-5-oxyacetic acid (cmo5U) to uridine-5-oxyacetic acid methyl ester (mcmo5U) (By similarity)
C2U40_13745	ENOG4105PFA	Catalyzes the conversion of 5-hydroxyuridine (ho5U) to 5-methoxyuridine (mo5U) at position 34 in tRNA (By similarity)
C2U40_13765	ENOG4105D3R	alkyl hydroperoxide reductase
C2U40_13770	ENOG4105C5Q	Transcriptional regulator
C2U40_13780	ENOG4107TT5	NLP P60 protein
C2U40_13790	ENOG4107RGH	Aldehyde dehydrogenase
C2U40_13795	ENOG4107Z3H	Transcriptional regulator, TetR family
C2U40_13815	ENOG4105C6T	cysteine synthase
C2U40_13835	ENOG4105UQX	Mate efflux family protein
C2U40_13850	ENOG4105D95	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin (By similarity)
C2U40_13860	ENOG4105QVC	MOSC domain-containing protein
C2U40_13860	ENOG4105QVC	MOSC domain-containing protein
C2U40_13870	ENOG4107SDU	Methyl-accepting chemotaxis
C2U40_13875	ENOG4105D0M	Protease HtpX homolog
C2U40_13880	ENOG4105E78	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity)
C2U40_13885	ENOG410626R	Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity)
C2U40_13890	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
C2U40_13895	ENOG4105CZF	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism (By similarity)
C2U40_13915	ENOG4105C5S	asparaginyl-tRNA synthetase
C2U40_13920	ENOG4105DS2	Anaerobic c4-dicarboxylate transporter
C2U40_13935	ENOG4105CEE	C4-dicarboxylate transporter
C2U40_13965	ENOG4107TII	Recombinase
C2U40_13970	ENOG4105KUZ	arsenate reductase
C2U40_13975	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
C2U40_13990	ENOG4105C3N	Participates in control of cell volume in low-osmolarity conditions (By similarity)
C2U40_14010	ENOG410829K	Lysine exporter protein (Lyse ygga)
C2U40_14015	ENOG4108NVR	Methyl-accepting chemotaxis
C2U40_14020	ENOG4105RX8	Protein of unknown function (DUF1523)
C2U40_14035	ENOG4105DU0	nucleoside hydrolase
C2U40_14040	ENOG4105D3G	Pseudouridine synthase
C2U40_14045	ENOG4107SXA	Phosphorylase
C2U40_14050	ENOG4105C0A	alcohol dehydrogenase
C2U40_14055	ENOG4105YRI	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
C2U40_14060	ENOG4105K4T	epimerase
C2U40_14065	ENOG4105VDB	UPF0125 protein
C2U40_14070	ENOG4108Z1B	Cyclase dehydrase
C2U40_14075	ENOG4108UH4	Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity)
C2U40_14085	ENOG4105DFP	Integrase
C2U40_14095	ENOG4108P8R	
C2U40_14110	ENOG4108NF7	phage-type endonuclease
C2U40_14155	ENOG4105W5Q	DNA repair protein (RadC
C2U40_14210	ENOG4105F2I	Transposase
C2U40_14225	ENOG4105C0D	helicase
C2U40_14250	ENOG4105DZR	Type I site-specific deoxyribonuclease
C2U40_14290	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
C2U40_14300	ENOG4107QNK	)-transporter
C2U40_14305	ENOG4107HQ7	repeat protein
C2U40_14310	ENOG4108NZE	NAGC-like transcriptional regulator
C2U40_14315	ENOG4105W8I	Transcriptional regulator
C2U40_14320	ENOG4105BZC	d-serine deaminase
C2U40_14335	ENOG4108HMX	isocitrate dehydrogenase (NADP)
C2U40_14340	ENOG4106R3P	AraC family transcriptional regulator
C2U40_14345	ENOG4105EIP	mannose-6-phosphate isomerase
C2U40_14360	ENOG4105DM4	PTS System
C2U40_14375	ENOG4105C87	Aminotransferase class I and II
C2U40_14380	ENOG4105CI1	PTS System
C2U40_14385	ENOG4107P2S	Transcriptional regulator
C2U40_14420	ENOG4105DM4	PTS System
C2U40_14435	ENOG4105CXY	transporter
C2U40_14440	ENOG4108YRF	PTS System
C2U40_14450	ENOG4108R99	pseudouridine synthase
C2U40_14460	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
C2U40_14465	ENOG41075W9	High frequency lysogenization protein HflD homolog
C2U40_14470	ENOG4107QTF	adenylosuccinate lyase
C2U40_14475	ENOG4105EZE	Cupin 4 family protein
C2U40_14485	ENOG4108YYD	acetyltransferase
C2U40_14500	ENOG4108S7T	Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) (By similarity)
C2U40_14520	ENOG4105M2J	Glutaredoxin
C2U40_14525	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
C2U40_14530	ENOG410903C	(LipO)protein
C2U40_14535	ENOG4105KWW	Biogenesis protein
C2U40_14540	ENOG4105KWW	Biogenesis protein
C2U40_14545	ENOG4107QX9	Thiol disulfide interChange protein
C2U40_14550	ENOG4105DA4	cytochrome c-type biogenesis protein
C2U40_14555	ENOG4108ZKK	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH (By similarity)
C2U40_14560	ENOG4105X3C	heme exporter protein
C2U40_14565	ENOG41060IM	Heme exporter protein
C2U40_14570	ENOG4105CA5	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes (By similarity)
C2U40_14585	ENOG4108V3W	Chemotaxis protein, CheW
C2U40_14595	ENOG4107QJE	Chromosome Partitioning Protein
C2U40_14600	ENOG4108SEK	ompa motb domain protein
C2U40_14605	ENOG4105E14	MotA TolQ exbB proton channel
C2U40_14610	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
C2U40_14615	ENOG4105CBS	Chea signal transduction histidine kinase
C2U40_14620	ENOG4108KCC	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P) (By similarity)
C2U40_14625	ENOG4108VYJ	response regulator receiver protein
C2U40_14630	ENOG4105DN4	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
C2U40_14640	ENOG4105FZW	flagellar biosynthesis regulator FlhF
C2U40_14645	ENOG4105D7B	Flagellar biosynthesis protein flha
C2U40_14650	ENOG4105D00	flagellar biosynthetic protein flhB
C2U40_14655	ENOG4105D19	Role in flagellar biosynthesis (By similarity)
C2U40_14660	ENOG4105VS8	Flagellar biosynthetic protein fliq
C2U40_14665	ENOG4105CN7	Flagellar biosynthetic protein FliP
C2U40_14670	ENOG4105VTB	flagellar biosynthesis protein fliO
C2U40_14675	ENOG4105DD5	Flagellar motor switch protein
C2U40_14680	ENOG4105D24	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
C2U40_14700	ENOG4108JIR	Flagellum-specific ATP synthase
C2U40_14710	ENOG4105CS3	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
C2U40_14715	ENOG4105C1F	The M ring may be actively involved in energy transduction (By similarity)
C2U40_14720	ENOG4105VQ0	flagellar hook-basal body complex protein fliE
C2U40_14730	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
C2U40_14735	ENOG4105CBM	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 (By similarity)
C2U40_14740	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
C2U40_14755	ENOG4106KNT	transcriptional regulator
C2U40_14760	ENOG4105CA9	Pyruvate kinase
C2U40_14775	ENOG4105BZS	acriflavin resistance protein
C2U40_14780	ENOG4107QPN	acyl-Coa dehydrogenase
C2U40_14790	ENOG4107SSZ	Phosphatase
C2U40_14810	ENOG4107QMW	pyridine nucleotide-disulfide oxidoreductase
C2U40_14825	ENOG4105VYW	UPF0251 protein
C2U40_14830	ENOG4108RDD	Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine (By similarity)
C2U40_14835	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
C2U40_14840	ENOG4105F5W	AtP-binding protein
C2U40_14845	ENOG4105D70	Integrase catalytic subunit
C2U40_14850	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
C2U40_14910	ENOG4105E6M	Sulphatase-modifying factor protein
C2U40_14920	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
C2U40_14975	ENOG4107QKC	Oxidoreductase alpha (molybdopterin) subunit
C2U40_14980	ENOG4107H9G	Necessary for formate dehydrogenase activity (By similarity)
C2U40_14985	ENOG4105CBN	LysR family transcriptional regulator
C2U40_14995	ENOG4107N1Q	ErfK YbiS YcfS YnhG family protein
C2U40_15010	ENOG4105EBA	Specifically methylates the adenine in position 1618 of 23S rRNA (By similarity)
C2U40_15015	ENOG4107TT5	NLP P60 protein
C2U40_15025	ENOG4107QR8	Thioredoxin
C2U40_15035	ENOG4105C66	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity)
C2U40_15040	ENOG4105CIY	formyltetrahydrofolate deformylase
C2U40_15050	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
C2U40_15065	ENOG4108VC8	Peptidase family M23
C2U40_15075	ENOG4105E4C	Lytic transglycosylase catalytic
C2U40_15080	ENOG4105D8C	Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity)
C2U40_15085	ENOG4105NHU	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group (By similarity)
C2U40_15095	ENOG4105EP9	oxidoreductase
C2U40_15125	ENOG4105CCT	upf0313 protein
C2U40_15135	ENOG4105BZS	acriflavin resistance protein
C2U40_15140	ENOG4105J12	Multidrug resistance protein mdtN
C2U40_15145	ENOG4105BZU	Histidine kinase
C2U40_15150	ENOG4105D78	K07001 NTE family protein
C2U40_15155	ENOG4105C8J	)-transporter
C2U40_15175	ENOG4105UYK	outer membrane protein a
C2U40_15180	ENOG4105UYK	outer membrane protein a
C2U40_15185	ENOG4105UYK	outer membrane protein a
C2U40_15190	ENOG4107R1I	NAD-dependent malic enzyme
C2U40_15195	ENOG4105ECQ	AraC Family Transcriptional Regulator
C2U40_15200	ENOG4105UQX	Mate efflux family protein
C2U40_15205	ENOG4105RKX	Protein of unknown function (DUF2498)
C2U40_15210	ENOG4105BZU	Histidine kinase
C2U40_15215	ENOG4105C2W	permease
C2U40_15220	ENOG4108KMH	lipoate-protein ligase a
C2U40_15225	ENOG4105BZG	amino acid carrier protein
C2U40_15250	ENOG4105PTV	Nudix Hydrolase
C2U40_15270	ENOG4105CJ1	ABC, transporter
C2U40_15280	ENOG4108V1T	peptidylprolyl cis-trans isomerase
C2U40_15290	ENOG4106N3A	copper homeostasis protein cutc
C2U40_15305	ENOG4105ERG	peptidase m48, ste24p
C2U40_15315	ENOG4105BZU	Histidine kinase
C2U40_15320	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
C2U40_15325	ENOG4108ZI4	Glyoxalase Bleomycin resistance protein (Dioxygenase
C2U40_15330	ENOG4105C04	l-carnitine dehydratase bile acid-inducible protein F
C2U40_15335	ENOG4105C1G	acyl-Coa dehydrogenase
C2U40_15340	ENOG4108JU9	GAF modulated sigma54 specific transcriptional regulator Fis family
C2U40_15345	ENOG4105C26	Dehydrogenase
C2U40_15355	ENOG4108IPJ	Membrane
C2U40_15365	ENOG4106YYS	transcriptional regulatory protein
C2U40_15370	ENOG4105CEQ	signal transduction histidine kinase regulating citrate malate metabolism
C2U40_15375	ENOG4107R1I	NAD-dependent malic enzyme
C2U40_15390	ENOG4108US0	Transcription regulator that can specifically activate or repress expression of target genes (By similarity)
C2U40_15395	ENOG4105J12	Multidrug resistance protein mdtN
C2U40_15425	ENOG4108RDD	Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine (By similarity)
C2U40_15430	ENOG4105CJD	(Anaerobic) ribonucleoside-triphosphate reductase
C2U40_15440	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
C2U40_15450	ENOG4105CDB	Required for chromosome condensation and partitioning (By similarity)
C2U40_15455	ENOG4105EXN	Sulfate transport protein CysZ
C2U40_15460	ENOG4105EN6	Membrane
C2U40_15470	ENOG4105EAQ	(twin-arginine translocation) pathway signal
C2U40_15475	ENOG4105DIT	ErfK YbiS YcfS YnhG family protein
C2U40_15510	ENOG4107T9C	Alpha amylase catalytic region
C2U40_15545	ENOG4105BZU	Histidine kinase
C2U40_15550	ENOG4105D3U	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
C2U40_15555	ENOG4105C9K	Endothelin-converting enzyme 1
C2U40_15565	ENOG4105C5H	ABC transporter
C2U40_15575	ENOG4105DVH	amino acid
C2U40_15580	ENOG4105EXG	Transcriptional regulator
C2U40_15585	ENOG4107XDQ	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity)
C2U40_15590	ENOG4105C44	Serine transporter
C2U40_15595	ENOG4105EQ2	LysR family Transcriptional regulator
C2U40_15605	ENOG4107XGF	functions in a salvage pathway. Uses pyridoxamine (By similarity)
C2U40_15610	ENOG4105CXN	decarboxylase
C2U40_15615	ENOG4105D5Q	Arginine ornithine antiporter
C2U40_15620	ENOG4108M3R	transcriptional activator CadC
C2U40_15625	ENOG4107QM9	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA (By similarity)
C2U40_15630	ENOG4105C0B	DNA polymerase III (alpha subunit)
C2U40_15635	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
C2U40_15640	ENOG4105D0V	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
C2U40_15645	ENOG4105DAF	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
C2U40_15650	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
C2U40_15655	ENOG4105D7M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
C2U40_15660	ENOG4108RFI	Molecular chaperone that interacts specifically with outer membrane proteins, thus maintaining the solubility of early folding intermediates during passage through the periplasm (By similarity)
C2U40_15670	ENOG4105DZP	Membrane-associated zinc metalloprotease
C2U40_15675	ENOG4105CEA	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity)
C2U40_15680	ENOG4105KNE	Phosphatidate cytidylyltransferase
C2U40_15685	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
C2U40_15690	ENOG4108VCV	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity)
C2U40_15695	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
C2U40_15700	ENOG4105CU7	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity)
C2U40_15705	ENOG4105CE9	30S ribosomal protein S2
C2U40_15710	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
C2U40_15715	ENOG4105E1P	Modifies, by uridylylation or deuridylylation the PII (GlnB) regulatory protein (By similarity)
C2U40_15720	ENOG4105DMJ	Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate (By similarity)
C2U40_15725	ENOG4108T8E	UPF0325 protein
C2U40_15730	ENOG4105CI1	PTS System
C2U40_15735	ENOG4107W52	maltose operon periplasmic protein
C2U40_15745	ENOG4105QDK	Flavodoxin
C2U40_15750	ENOG4105DR9	pseudouridine synthase
C2U40_15755	ENOG4105WP7	tRNA pseudouridine synthase C
C2U40_15780	ENOG4105EXF	Zn-ribbon-containing, possibly nucleic-acid-binding protein
C2U40_15785	ENOG4108T6E	Interacts with the SecY protein in vivo. May bind preferentially to an uncomplexed state of SecY, thus functioning either as a chelating agent for excess SecY in the cell or as a regulatory factor that negatively controls the translocase function (By similarity)
C2U40_15790	ENOG4107R1K	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) (By similarity)
C2U40_15800	ENOG4105BZU	Histidine kinase
C2U40_15805	ENOG4105EWT	decarboxylase family
C2U40_15810	ENOG4105CIQ	May have a role in processing of nucleic acids. It is probably not an exonuclease
C2U40_15815	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
C2U40_15825	ENOG4105EZ6	Catalyzes the 2'-O-methylation at nucleotide C2498 in 23S rRNA (By similarity)
C2U40_15830	ENOG4105M08	Membrane
C2U40_15840	ENOG4105ETT	transcriptional Regulator, LysR family
C2U40_15845	ENOG4105C8Q	Methyl-accepting chemotaxis
C2U40_15850	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
C2U40_15865	ENOG4105CJ2	(LipO)protein
C2U40_15870	ENOG4105D26	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. The first step is catalyzed by NqrF, which accepts electrons from NADH and reduces ubiquinone-1 to ubisemiquinone by a one-electron transfer pathway (By similarity)
C2U40_15875	ENOG4108IUB	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
C2U40_15880	ENOG4105F5D	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
C2U40_15885	ENOG4106I92	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
C2U40_15890	ENOG4108J5C	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
C2U40_15895	ENOG4105DWQ	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
C2U40_15900	ENOG4105M85	Bola protein
C2U40_15905	ENOG4105D8J	Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle (By similarity)
C2U40_15915	ENOG4108R5K	PPIases accelerate the folding of proteins (By similarity)
C2U40_15925	ENOG4105EYM	Major Facilitator superfamily
C2U40_15930	ENOG4105DRB	nucleoside-specific channel-forming protein
C2U40_15935	ENOG4108VPT	UPF0234 protein
C2U40_15940	ENOG4108JZF	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity)
C2U40_15945	ENOG4107S0N	DJ-1 family
C2U40_15950	ENOG4105C7K	acetolactate synthase
C2U40_15990	ENOG4105CS6	Rhs element vgr protein
C2U40_16000	ENOG4108WC9	type VI secretion system effector, hcp1 family
C2U40_16005	ENOG4105VJY	transcriptional regulator
C2U40_16020	ENOG4105CKT	filamentous hemagglutinin
C2U40_16060	ENOG4105D5K	Hemolysin activator protein
C2U40_16075	ENOG4105DRC	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity)
C2U40_16080	ENOG4105CMR	udp-glucose 4-epimerase
C2U40_16090	ENOG4105EJ7	Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O (By similarity)
C2U40_16095	ENOG4108RMU	ferritin dps family protein
C2U40_16120	ENOG4105CV9	cyclopropane-fatty-acyl-phospholipid synthase
C2U40_16135	ENOG4105EMU	Dehydrogenase
C2U40_16145	ENOG4105CVP	deoxyribo-dipyrimidine photolyase
C2U40_16295	ENOG4106FE3	DNA repair
C2U40_16385	ENOG4108WTW	DNA transposition protein
C2U40_16410	ENOG4107SEY	Conserved Protein
C2U40_16440	ENOG4105CQC	Prephenate dehydratase
C2U40_16470	ENOG4108NF7	phage-type endonuclease
C2U40_16500	ENOG4105CVR	type I restriction-modification system
C2U40_16540	ENOG4105W5Q	DNA repair protein (RadC
C2U40_16580	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
C2U40_16615	ENOG4107R3N	Filamentation induced by cAMP protein fic
C2U40_16645	ENOG4105D8V	Glucose sorbosone dehydrogenase
C2U40_16655	ENOG4108W2P	Methyl-accepting chemotaxis
C2U40_16660	ENOG4105J5J	Outer membrane porin
C2U40_16665	ENOG4105E1F	short-chain dehydrogenase reductase
C2U40_16690	ENOG4105CTD	carboxy-peptidase
C2U40_16705	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
C2U40_16725	ENOG4105CFP	Peptidase U32
C2U40_16730	ENOG4105N14	lysine exporter protein LysE YggA
C2U40_16740	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
C2U40_16745	ENOG4105C8Q	Methyl-accepting chemotaxis
C2U40_16750	ENOG4108VYJ	response regulator receiver protein
C2U40_16760	ENOG4105CBS	Chea signal transduction histidine kinase
C2U40_16770	ENOG4108V3W	Chemotaxis protein, CheW
C2U40_16775	ENOG4105C8Q	Methyl-accepting chemotaxis
C2U40_16780	ENOG4105BZU	Histidine kinase
C2U40_16785	ENOG4108Z4W	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis (By similarity)
C2U40_16790	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
C2U40_16795	ENOG4105C9B	Cysteine desulfurase
C2U40_16820	ENOG4105BZU	Histidine kinase
C2U40_16825	ENOG41068CG	regulatoR
C2U40_16835	ENOG4108N3D	putative enzyme
C2U40_16850	ENOG4108NJZ	Sensory box GGDEF EAL domain protein
C2U40_16855	ENOG4105CFP	Peptidase U32
C2U40_16860	ENOG4105K5D	4fe-4S ferredoxin iroN-sulfur binding
C2U40_16870	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
C2U40_16875	ENOG4105CDU	Replicative dna helicase
C2U40_16890	ENOG4105BZU	Histidine kinase
C2U40_16895	ENOG4105CGH	5'-nucleotidase
C2U40_16915	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
C2U40_16920	ENOG4105VNT	transposase (IS4 family) protein
C2U40_16925	ENOG4108V1T	peptidylprolyl cis-trans isomerase
C2U40_16935	ENOG4105VRX	Protein slyX homolog
C2U40_16940	ENOG4105VNT	transposase (IS4 family) protein
C2U40_16945	ENOG4108YZY	peptidylprolyl cis-trans isomerase
C2U40_16950	ENOG4105VKU	nucleicacid-binding protein
C2U40_16960	ENOG4107R88	Chemotaxis protein (CheV)
C2U40_16965	ENOG4105DNZ	Alpha Beta Hydrolase
C2U40_16975	ENOG4105YP7	UPF0270 protein
C2U40_16980	ENOG4105C6Y	Udp-glucose 6-dehydrogenase
C2U40_16985	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
C2U40_16990	ENOG4105CKK	Glycosyl transferase, family 2
C2U40_16995	ENOG4108I2E	Bifunctional enzyme that catalyzes the oxidative decarboxylation of UDP-glucuronic acid (UDP-GlcUA) to UDP-4-keto- arabinose (UDP-Ara4O) and the addition of a formyl group to UDP-4- amino-4-deoxy-L-arabinose (UDP-L-Ara4N) to form UDP-L-4-formamido- arabinose (UDP-L-Ara4FN). The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides (By similarity)
C2U40_17000	ENOG4105F73	Catalyzes the deformylation of 4-deoxy-4-formamido-L- arabinose-phosphoundecaprenol to 4-amino-4-deoxy-L-arabinose- phosphoundecaprenol. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides (By similarity)
C2U40_17005	ENOG4105SA9	Catalyzes the transfer of the L-Ara4N moiety of the glycolipid undecaprenyl phosphate-alpha-L-Ara4N to lipid A. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides (By similarity)
C2U40_17010	ENOG41060GT	Translocates 4-amino-4-deoxy-L-arabinose- phosphoundecaprenol (alpha-L-Ara4N-phosphoundecaprenol) from the cytoplasmic to the periplasmic side of the inner membrane (By similarity)
C2U40_17015	ENOG4105PE8	Translocates 4-amino-4-deoxy-L-arabinose- phosphoundecaprenol (alpha-L-Ara4N-phosphoundecaprenol) from the cytoplasmic to the periplasmic side of the inner membrane (By similarity)
C2U40_17020	ENOG4105CJE	phosphoribulokinase (EC 2.7.1.19)
C2U40_17035	ENOG4108UKZ	OsmC family
C2U40_17040	ENOG4107RYR	Transcriptional regulator, Crp Fnr family
C2U40_17045	ENOG4105DHI	Methyltransferase
C2U40_17050	ENOG4108M1A	Chitin-binding protein
C2U40_17055	ENOG4108MA4	Peptidase M66
C2U40_17065	ENOG4105BZU	Histidine kinase
C2U40_17075	ENOG4105VMP	Transcriptional regulator
C2U40_17080	ENOG4105D8G	Major Facilitator superfamily
C2U40_17090	ENOG4105D05	Receptor
C2U40_17110	ENOG4105PYN	Pyridoxamine 5-phosphate oxidase-related
C2U40_17115	ENOG41090JE	Utilization Protein
C2U40_17125	ENOG4105EHG	Permease protein
C2U40_17155	ENOG4105D9N	nucleoside
C2U40_17160	ENOG4107U5R	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate (By similarity)
C2U40_17180	ENOG4105E4C	Lytic transglycosylase catalytic
C2U40_17185	ENOG4105DUF	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively (By similarity)
C2U40_17205	ENOG4105C5H	ABC transporter
C2U40_17215	ENOG4105C7N	Xanthine uracil vitamin C permease
C2U40_17220	ENOG41066UG	Regulatory DnaK co-chaperone. Direct interaction between DnaK and DjlA is needed for the induction of the wcaABCDE operon, involved in the synthesis of a colanic acid polysaccharide capsule, possibly through activation of the RcsB RcsC phosphotransfer signaling pathway. The colanic acid capsule may help the bacterium survive conditions outside the host (By similarity)
C2U40_17225	ENOG4108S0S	Nucleotidyl transferase
C2U40_17230	ENOG4105EHM	Aminoglycoside phosphotransferase
C2U40_17235	ENOG4105E7H	involved in the assembly of LPS in the outer leaflet of the outer membrane. Determines N-hexane tolerance and is involved in outer membrane permeability. Essential for envelope biogenesis (By similarity)
C2U40_17245	ENOG4105CEZ	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) (By similarity)
C2U40_17250	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
C2U40_17255	ENOG4105NWN	ApaG protein
C2U40_17260	ENOG4105DDT	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP (By similarity)
C2U40_17275	ENOG4105DEN	Luciferase family
C2U40_17280	ENOG4108ESY	Metal dependent phosphohydrolase
C2U40_17295	ENOG4105CEY	Amp-dependent synthetase and ligase
C2U40_17300	ENOG4105DWD	nucleoside recognition domain protein
C2U40_17305	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
C2U40_17310	ENOG4105K46	50S ribosomal protein l27
C2U40_17315	ENOG4105KK9	This protein binds to 23S rRNA in the presence of protein L20 (By similarity)
C2U40_17320	ENOG4105EAH	synthase
C2U40_17330	ENOG4105EPW	hflc protein
C2U40_17335	ENOG4107QJR	hflk protein
C2U40_17340	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
C2U40_17345	ENOG4105KW8	RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity)
C2U40_17350	ENOG4105DKX	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity)
C2U40_17355	ENOG4105DC6	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity)
C2U40_17360	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
C2U40_17365	ENOG4105K8N	protein family UPF0079, ATPase
C2U40_17370	ENOG4105DR1	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)
C2U40_17375	ENOG4105EH2	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity)
C2U40_17390	ENOG4108JEI	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity)
C2U40_17395	ENOG4108UMI	ABC transporter, permease
C2U40_17400	ENOG4105D01	(LipO)protein
C2U40_17405	ENOG4105MDZ	Transcriptional activator rfaH
C2U40_17410	ENOG4108N3W	hemolysin secretion protein
C2U40_17415	ENOG4105BZU	Histidine kinase
C2U40_17420	ENOG4105BZU	Histidine kinase
C2U40_17430	ENOG4105C4Q	deoxyguanosinetriphosphate triphosphohydrolase-like protein
C2U40_17435	ENOG4105BZU	Histidine kinase
C2U40_17455	ENOG4106173	Uncharacterized protein conserved in bacteria (DUF2057)
C2U40_17460	ENOG4105EXG	Transcriptional regulator
C2U40_17470	ENOG4107QWK	SAICAR synthetase
C2U40_17475	ENOG4107EG0	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
C2U40_17480	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
C2U40_17485	ENOG4105RH4	Glycine cleavage system transcriptional repressor
C2U40_17490	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
C2U40_17495	ENOG4105XWI	UPF0304 protein
C2U40_17500	ENOG4105PQ6	UPF0208 membrane protein
C2U40_17505	ENOG4105C6H	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity)
C2U40_17510	ENOG4105C6K	Malic enzyme
C2U40_17515	ENOG4108ZP8	Acetolactate synthase small subunit
C2U40_17525	ENOG4105C7K	acetolactate synthase
C2U40_17535	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
C2U40_17540	ENOG4105YVM	Phosphoesterase, PA-phosphatase related
C2U40_17550	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
C2U40_17560	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
C2U40_17565	ENOG4105MQS	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
C2U40_17580	ENOG4105DP9	ABC transporter
C2U40_17585	ENOG4106SMU	thiamine transporter membrane protein
C2U40_17590	ENOG4107T0D	ABC, transporter
C2U40_17595	ENOG4108IAB	Phoh family
C2U40_17605	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
C2U40_17635	ENOG4108YX9	iron--sulfur cluster insertion protein erpA
C2U40_17645	ENOG4105CMQ	Chloride channel
C2U40_17650	ENOG4105CDM	Glutamate-1-semialdehyde aminotransferase
C2U40_17665	ENOG41076MN	Phosphoesterase, PA-phosphatase related
C2U40_17680	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
C2U40_17690	ENOG41090TI	Catalyzes the excretion of spermidine (By similarity)
C2U40_17695	ENOG4108ZBZ	Catalyzes the excretion of spermidine (By similarity)
C2U40_17700	ENOG4108YZK	glyoxalase bleomycin resistance protein dioxygenase
C2U40_17705	ENOG4105BZ4	penicillin-binding protein
C2U40_17710	ENOG4105CQ7	ATP-dependent helicase
C2U40_17720	ENOG4105PW4	Sugar fermentation stimulation protein homolog
C2U40_17725	ENOG4108V7X	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
C2U40_17730	ENOG4106F3G	Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon (By similarity)
C2U40_17735	ENOG4105DJ0	Poly(A) Polymerase
C2U40_17740	ENOG4105K8U	2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
C2U40_17745	ENOG4105CCG	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is tranferred onto alpha-ketoisovalerate to form ketopantoate (By similarity)
C2U40_17750	ENOG4108IAA	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate (By similarity)
C2U40_17770	ENOG4105CIZ	coA-substrate-specific enzyme activase
C2U40_17775	ENOG4105DCU	2-hydroxyglutaryl-CoA dehydratase
C2U40_17780	ENOG4105E3A	(ABC) transporter
C2U40_17785	ENOG4105DA5	(ABC) transporter
C2U40_17790	ENOG4108UGV	hypoxanthine phosphoribosyltransferase
C2U40_17795	ENOG410630P	Transcriptional regulator
C2U40_17800	ENOG4108UMA	3-octaprenyl-4-hydroxybenzoate carboxy-lyase
C2U40_17805	ENOG4105DFU	Cell wall formation (By similarity)
C2U40_17810	ENOG4105F0N	pyrophosphate phospho-hydrolase
C2U40_17835	ENOG4108UUE	Transcriptional regulator
C2U40_17870	ENOG4107RHT	methyl-accepting chemotaxis sensory transducer with Pas Pac sensor
C2U40_17890	ENOG4108I67	Catalyzes the synthesis of activated sulfate (By similarity)
C2U40_17900	ENOG4105C3T	may be the GTPase, regulating ATP sulfurylase activity (By similarity)
C2U40_17905	ENOG4105C11	sulfate adenylyltransferase), subunit 2
C2U40_17910	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
C2U40_17915	ENOG4107QX8	SPFH domain, Band 7 family protein
C2U40_17920	ENOG4105G5H	Membrane
C2U40_17925	ENOG4105C2X	Arabinose 5-phosphate isomerase
C2U40_17930	ENOG4105C5H	ABC transporter
C2U40_17940	ENOG4105D6S	protein involved in catabolism of external DNA
C2U40_17945	ENOG4105EQ2	LysR family Transcriptional regulator
C2U40_17990	ENOG4105CK7	Sodium proline symporter
C2U40_17995	ENOG4107N1Q	ErfK YbiS YcfS YnhG family protein
C2U40_18000	ENOG4105CUY	Mechanosensitive ion channel
C2U40_18010	ENOG4105XEP	YhcH YjgK YiaL family protein
C2U40_18020	ENOG4105E3B	Multicopper oxidase
C2U40_18035	ENOG4107SQD	Transcriptional regulator, GntR family
C2U40_18060	ENOG4105C8J	)-transporter
C2U40_18070	ENOG4105C8J	)-transporter
C2U40_18085	ENOG4108K4B	hydrolase
C2U40_18100	ENOG4105J0Q	Transcriptional regulator
C2U40_18115	ENOG4105K56	Transcriptional regulator
C2U40_18120	ENOG4108ZHJ	Organic hydroperoxide resistance protein
C2U40_18125	ENOG4105CJH	Alcohol dehydrogenase zinc-binding domain protein
C2U40_18130	ENOG4105EJF	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity)
C2U40_18140	ENOG4105E0X	reductase
C2U40_18150	ENOG4105C9C	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity)
C2U40_18155	ENOG4107RTM	4-alpha-glucanotransferase (EC 2.4.1.25)
C2U40_18160	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
C2U40_18165	ENOG4105DSB	aldose 1-epimerase
C2U40_18170	ENOG4105D0I	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate (By similarity)
C2U40_18175	ENOG4105C8Q	Methyl-accepting chemotaxis
C2U40_18250	ENOG4105UFD	tol-pal system protein YbgF
C2U40_18255	ENOG4105KCK	Peptidoglycan-associated lipoprotein
C2U40_18260	ENOG4107R6Y	Involved in the TonB-independent uptake of proteins (By similarity)
C2U40_18270	ENOG4105M8F	Biopolymer transport protein exbD tolR
C2U40_18275	ENOG4105E02	MotA TolQ exbB proton channel
C2U40_18280	ENOG4107YD3	Thioesterase
C2U40_18285	ENOG4105KJB	cyd operon protein YbgE
C2U40_18295	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
C2U40_18300	ENOG4105C4M	(Ubiquinol oxidase) subunit I
C2U40_18305	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
C2U40_18310	ENOG4105KA4	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity)
C2U40_18315	ENOG4105C8Q	Methyl-accepting chemotaxis
C2U40_18320	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
C2U40_18325	ENOG4108RZ4	Short-chain dehydrogenase reductase Sdr
C2U40_18340	ENOG4105E39	Enoyl-CoA hydratase
C2U40_18345	ENOG4106WH9	Protein of unknown function (DUF2753)
C2U40_18350	ENOG4105EQK	-acetyltransferase
C2U40_18360	ENOG4107QSI	ABC, transporter
C2U40_18375	ENOG4105VZ9	UPF0235 protein
C2U40_18380	ENOG4108VIA	integral membrane protein
C2U40_18385	ENOG4105II7	pyrroline-5-carboxylate reductase
C2U40_18390	ENOG4105DFA	alanine racemase domain protein
C2U40_18395	ENOG4105CZX	twitching motility protein
C2U40_18400	ENOG4105CZX	twitching motility protein
C2U40_18405	ENOG4105D1Q	UPF0246 protein
C2U40_18410	ENOG4105C1J	atp-dependent rna helicase
C2U40_18415	ENOG4107S47	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC) (By similarity)
C2U40_18420	ENOG4105CWM	branched-chain amino acid transport system II carrier protein
C2U40_18425	ENOG4105CWM	branched-chain amino acid transport system II carrier protein
C2U40_18440	ENOG4105MYN	Zinc uptake regulation protein
C2U40_18445	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
C2U40_18460	ENOG4105K70	DNA-binding protein
C2U40_18465	ENOG4108ZVW	Anti-RNA polymerase sigma 70 factor
C2U40_18475	ENOG4105DNJ	May play a role in the repair of endogenous alkylation damage (By similarity)
C2U40_18490	ENOG4105EAC	phosphoserine phosphatase
C2U40_18500	ENOG4105BZU	Histidine kinase
C2U40_18505	ENOG4105D3A	purine nucleoside phosphorylase DeoD-type
C2U40_18510	ENOG4105CZG	Phosphotransfer between the C1 and C5 carbon atoms of pentose (By similarity)
C2U40_18515	ENOG4105CMW	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis (By similarity)
C2U40_18520	ENOG4105FCI	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate (By similarity)
C2U40_18530	ENOG4105D9N	nucleoside
C2U40_18535	ENOG4105EYA	deoxyribonuclease
C2U40_18550	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
C2U40_18555	ENOG4105BZU	Histidine kinase
C2U40_18560	ENOG4108IYS	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
C2U40_18570	ENOG41087BU	transcriptional repressor DicA
C2U40_18650	ENOG4105RVE	Uncharacterized protein conserved in bacteria (DUF2136)
C2U40_18655	ENOG4108Z3N	Transcriptional regulator
C2U40_18665	ENOG4105ED4	portal protein
C2U40_18720	ENOG4105KSC	Transcriptional regulator, TraR DksA family
C2U40_18800	ENOG4108K5H	permease YjgP YjgQ family protein
C2U40_18805	ENOG4108M8S	permease YjgP YjgQ family protein
C2U40_18810	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
C2U40_18815	ENOG4105MYG	DNA polymerase iii, chi subunit
C2U40_18820	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
C2U40_18830	ENOG4106W5V	Membrane
C2U40_18835	ENOG41061WM	D-Alanyl-D-Alanine
C2U40_18870	ENOG4105VM8	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding (By similarity)
C2U40_18875	ENOG4105CFH	Aspartokinase
C2U40_18880	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
C2U40_18890	ENOG4105C68	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity)
C2U40_18895	ENOG4107TH8	cina domain protein
C2U40_18905	ENOG4108NF7	phage-type endonuclease
C2U40_18925	ENOG4105W5Q	DNA repair protein (RadC
C2U40_18945	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
C2U40_18960	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
C2U40_18980	ENOG4105DZR	Type I site-specific deoxyribonuclease
C2U40_19015	ENOG4105JXR	Protein of unknown function (DUF3296)
C2U40_19030	ENOG4105DFP	Integrase
C2U40_19035	ENOG4105D86	that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity)
C2U40_19060	ENOG4105R2J	Conserved Protein
C2U40_19070	ENOG4105DR5	peptidase
C2U40_19090	ENOG4105NXV	High-affinity zinc uptake system protein
C2U40_19095	ENOG4105FDK	ABC transporter
C2U40_19100	ENOG4105FAV	ABC, transporter
C2U40_19105	ENOG4105ETT	transcriptional Regulator, LysR family
C2U40_19115	ENOG4108RG0	uracil-dna glycosylase
C2U40_19120	ENOG4105FR1	rard protein
C2U40_19130	ENOG41082IR	Excinuclease ABC C subunit domain protein
C2U40_19145	ENOG41087YS	Phage shock protein A
C2U40_19150	ENOG4107S7E	1-acyl-sn-glycerol-3-phosphate acyltransferase
C2U40_19170	ENOG4105N2G	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
C2U40_19175	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
C2U40_19205	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
C2U40_19210	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
C2U40_19215	ENOG4105DSW	Fusaric acid resistance protein
C2U40_19220	ENOG4105Y49	secretion protein, HlyD family
C2U40_19240	ENOG4105IPS	esterase
C2U40_19245	ENOG41070EG	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes (By similarity)
C2U40_19250	ENOG4108SX3	cytoplasmic protein
C2U40_19255	ENOG41087AY	ADP-Ribose pyrophosphatase
C2U40_19260	ENOG4105DFG	type I secretion outer membrane protein
C2U40_19265	ENOG4105DW0	Catalyzes the ADP transfer to D-glycero-D-manno-heptose 1-phosphate, yielding ADP-D,D-heptose (By similarity)
C2U40_19270	ENOG4105D1S	lipid A biosynthesis
C2U40_19285	ENOG4107IX6	phosphate transport regulator
C2U40_19290	ENOG4105CJ3	phosphate transporter
C2U40_19295	ENOG4108Z66	YbaK ebsC protein
C2U40_19300	ENOG41072TH	Protein of unknown function (DUF1479)
C2U40_19325	ENOG4105CMU	LysR family (Transcriptional regulator
C2U40_19335	ENOG41067MG	lrgb family
C2U40_19350	ENOG4105D4J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
C2U40_19365	ENOG4105CEN	a g-specific adenine glycosylase
C2U40_19370	ENOG4105KMG	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes (By similarity)
C2U40_19380	ENOG4105H4F	exported protein
C2U40_19395	ENOG4105UYK	outer membrane protein a
C2U40_19400	ENOG4108Q2G	(LipO)protein
C2U40_19405	ENOG4105DY2	Paraquat-inducible protein b
C2U40_19410	ENOG4105F1S	paraquat-inducible protein a
C2U40_19415	ENOG4105KW8	RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity)
C2U40_19420	ENOG4107VXZ	Hydrolase
C2U40_19435	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
C2U40_19440	ENOG4105D8J	Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle (By similarity)
C2U40_19445	ENOG4107QQ4	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans (By similarity)
C2U40_19450	ENOG4105CXW	Synthesizes alpha-1,4-glucan chains using ADP-glucose (By similarity)
C2U40_19490	ENOG4105DFD	Na H antiporter
C2U40_19495	ENOG4108M0I	Transcriptional regulator
C2U40_19500	ENOG4107TYH	extracellular solute-binding protein family 1
C2U40_19505	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
C2U40_19510	ENOG4105D81	ABC transporter, permease
C2U40_19515	ENOG4105NRK	Binding-protein-dependent transport systems, inner membrane component
C2U40_19520	ENOG4105C26	Dehydrogenase
C2U40_19525	ENOG4105YYA	enhanced serine sensitivity protein SseB
C2U40_19585	ENOG4107AQZ	Membrane
C2U40_19595	ENOG4108UW5	maltose o-acetyltransferase
C2U40_19600	ENOG4105CG3	alpha amylase, catalytic region
C2U40_19605	ENOG4105C5Y	PTS System
C2U40_19610	ENOG4105D4X	repressor
C2U40_19625	ENOG4105HDK	L-asparaginase
C2U40_19640	ENOG4108Z5K	methylglyoxal synthase
C2U40_19650	ENOG4108UQY	Iron-storage protein
C2U40_19665	ENOG4105E0I	Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of tRNA(Met), by using acetyl-CoA as an acetyl donor and ATP (or GTP) (By similarity)
C2U40_19675	ENOG4107R88	Chemotaxis protein (CheV)
C2U40_19680	ENOG4105DWD	nucleoside recognition domain protein
C2U40_19720	ENOG4105K7Z	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP (By similarity)
C2U40_19725	ENOG4107ZVW	dihydroneopterin aldolase
C2U40_19730	ENOG4105K8U	2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
C2U40_19740	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
C2U40_19745	ENOG4105CKI	cobalamin synthesis protein
C2U40_19755	ENOG4105E82	cytochrome subunit of dehydrogenase
C2U40_19765	ENOG4105BZU	Histidine kinase
C2U40_19770	ENOG4107QIJ	Aconitate hydratase 2
C2U40_19775	ENOG4105D78	K07001 NTE family protein
C2U40_19780	ENOG4108N3W	hemolysin secretion protein
C2U40_19785	ENOG4108N3W	hemolysin secretion protein
C2U40_19795	ENOG4107QN2	dihydrolipoyl dehydrogenase
C2U40_19800	ENOG4107QSN	dihydrolipoamide acetyltransferase
C2U40_19805	ENOG4105DAQ	Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) (By similarity)
C2U40_19810	ENOG41073TP	transcriptional regulator
C2U40_19825	ENOG4105D18	nicotinate-nucleotide pyrophosphorylase
C2U40_19840	ENOG4107QHF	type ii secretion system protein e
C2U40_19845	ENOG4105D7Q	type ii secretion system
C2U40_19860	ENOG4105DHA	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity (By similarity)
C2U40_19865	ENOG41067SF	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase (By similarity)
C2U40_19870	ENOG4105EJF	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity)
C2U40_19880	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
C2U40_19890	ENOG4105C7C	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
C2U40_19895	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
C2U40_19900	ENOG4105CIT	This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity)
C2U40_19905	ENOG4105K7E	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly (By similarity)
C2U40_19910	ENOG4105DFU	Cell wall formation (By similarity)
C2U40_19915	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
C2U40_19920	ENOG4105CNI	cell division protein FtsW
C2U40_19925	ENOG4105DMZ	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity)
C2U40_19930	ENOG4105CPY	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity)
C2U40_19935	ENOG4108EQQ	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein (By similarity)
C2U40_19940	ENOG4107EEN	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity)
C2U40_19945	ENOG4105CJN	penicillin-binding protein
C2U40_19950	ENOG41063Y6	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity)
C2U40_19955	ENOG4105CGJ	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity)
C2U40_19960	ENOG4108V6E	Cell division protein mraZ
C2U40_19970	ENOG4105E9H	Lytic Murein transglycosylase
C2U40_19980	ENOG4105ER2	Ompa motb domain protein
C2U40_19985	ENOG4107RD7	Flagellar Motor Protein, MotA
C2U40_20010	ENOG4105MQ3	flagellar protein FliS
C2U40_20015	ENOG410804A	Flagellar hook-associated 2 domain-containing protein
C2U40_20020	ENOG4105I03	Flagellin
C2U40_20035	ENOG4105DTJ	flagellar hook-associated protein
C2U40_20040	ENOG4105E1Q	flagellar hook-associated protein
C2U40_20050	ENOG4105D92	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity)
C2U40_20055	ENOG4107W7W	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity)
C2U40_20060	ENOG4105CGA	flagellar basal-body rod protein FlgG
C2U40_20065	ENOG4108KPB	Flagellar basal-body rod protein FlgF
C2U40_20070	ENOG4105BZE	flagellar hook protein, FlgE
C2U40_20075	ENOG4105W00	Flagellar hook capping protein
C2U40_20080	ENOG4108ZC9	flagellar basal-body rod protein flgc
C2U40_20085	ENOG4105K88	Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body (By similarity)
C2U40_20110	ENOG4108JIR	Flagellum-specific ATP synthase
C2U40_20120	ENOG4105CS3	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
C2U40_20125	ENOG4105C1F	The M ring may be actively involved in energy transduction (By similarity)
C2U40_20130	ENOG4105VQ0	flagellar hook-basal body complex protein fliE
C2U40_20135	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
C2U40_20145	ENOG4105D00	flagellar biosynthetic protein flhB
C2U40_20150	ENOG4105D19	Role in flagellar biosynthesis (By similarity)
C2U40_20155	ENOG4105VS8	Flagellar biosynthetic protein fliq
C2U40_20160	ENOG4105CN7	Flagellar biosynthetic protein FliP
C2U40_20165	ENOG4105DD5	Flagellar motor switch protein
C2U40_20180	ENOG4105CU0	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity)
C2U40_20185	ENOG4105E1C	Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1A (PBP1a) (By similarity)
C2U40_20190	ENOG41082RQ	UPF0102 protein
C2U40_20195	ENOG4105F55	Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate (By similarity)
C2U40_20200	ENOG4105W4M	Transport-associated protein
C2U40_20210	ENOG4105KB2	stringent starvation protein b
C2U40_20215	ENOG4107MKT	Stringent starvation protein a
C2U40_20220	ENOG4105EIX	cytochrome c1
C2U40_20225	ENOG4105DJ5	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
C2U40_20230	ENOG4108R5F	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
C2U40_20235	ENOG4108UJD	30S ribosomal protein S9
C2U40_20240	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
C2U40_20245	ENOG4105D6Z	AFG1 family ATPase
C2U40_20255	ENOG4105C0H	protease
C2U40_20260	ENOG4105C0H	protease
C2U40_20290	ENOG41069H0	dihydroorotase EC 3.5.2.3
C2U40_20305	ENOG4105EMD	TRANSCRIPTIONal
C2U40_20310	ENOG41080Z8	PHOSPHOCARRIER protein
C2U40_20315	ENOG4105C21	Displays ATPase and GTPase activities (By similarity)
C2U40_20320	ENOG4107RM2	PTS IIA-like nitrogen-regulatory protein PtsN
C2U40_20325	ENOG41080QH	sigma 54 modulation protein ribosomal protein S30EA
C2U40_20330	ENOG4105DTW	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
C2U40_20335	ENOG4108IUZ	ABC transporter
C2U40_20340	ENOG4105WI0	lipopolysaccharide transport periplasmic protein lptA
C2U40_20345	ENOG4108P1K	Required for the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane (By similarity)
C2U40_20350	ENOG4108Z4R	3-deoxy-d-manno-octulosonate 8-phosphate phosphatase
C2U40_20355	ENOG4105C2X	Arabinose 5-phosphate isomerase
C2U40_20360	ENOG4105DHJ	ABC, transporter
C2U40_20365	ENOG4105CY3	ABC transporter, permease
C2U40_20370	ENOG4107PE3	Mammalian cell entry related domain protein
C2U40_20375	ENOG4105E3I	toluene tolerance
C2U40_20385	ENOG4105VFK	BolA family
C2U40_20390	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
C2U40_20395	ENOG4105CMS	peptidase U62, modulator of DNA gyrase
C2U40_20400	ENOG4105N42	UPF0307 protein
C2U40_20415	ENOG41090HJ	UPF0265 protein
C2U40_20450	ENOG4108JCI	Transcriptional regulator
C2U40_20455	ENOG4105DKK	Benzoate
C2U40_20465	ENOG4105SYT	Methylenetetrahydrofolate reductase
C2U40_20485	ENOG4105EIF	outer membrane protein W
C2U40_20490	ENOG4105BZU	Histidine kinase
C2U40_20495	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
C2U40_20500	ENOG41086KC	Transcriptional regulator
C2U40_20505	ENOG4108UUM	single-stranded DNA-binding protein
C2U40_20520	ENOG41076HS	cation diffusion facilitator family transporter
C2U40_20530	ENOG4105VEQ	Cold shock protein
C2U40_20535	ENOG4105D05	Receptor
C2U40_20545	ENOG4105E0F	Histidine kinase
C2U40_20550	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
C2U40_20570	ENOG4108NVR	Methyl-accepting chemotaxis
C2U40_20590	ENOG4105KHA	Glyoxalase Bleomycin resistance protein (Dioxygenase
C2U40_20600	ENOG4107QYX	exodeoxyribonuclease v alpha
C2U40_20605	ENOG4107QKA	exodeoxyribonuclease V beta
C2U40_20610	ENOG4105DSY	exodeoxyribonuclease V, gamma
C2U40_20615	ENOG4108VBZ	doxx family
C2U40_20620	ENOG4105C2I	pirin domain protein
C2U40_20630	ENOG4105CWB	LysR family transcriptional Regulator
C2U40_20660	ENOG4105E4X	binding-protein-dependent transport systems inner membrane Component
C2U40_20670	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
C2U40_20680	ENOG4105BZU	Histidine kinase
C2U40_20700	ENOG4105WCN	acetyltransferase
C2U40_20705	ENOG4105CH6	catalase
C2U40_20735	ENOG4105IPI	Membrane
C2U40_20760	ENOG4105DWY	Agmatine deiminase
C2U40_20765	ENOG4105ETT	transcriptional Regulator, LysR family
C2U40_20770	ENOG4108JU9	GAF modulated sigma54 specific transcriptional regulator Fis family
C2U40_20785	ENOG4108UTZ	Dihydroxyacetone kinase
C2U40_20790	ENOG4105CMT	Dihydroxyacetone kinase
C2U40_20795	ENOG4105C7N	Xanthine uracil vitamin C permease
C2U40_20835	ENOG4108ZI0	d,d-heptose 1,7-bisphosphate phosphatase
C2U40_20840	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
C2U40_20845	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
C2U40_20850	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
C2U40_20855	ENOG4108UKE	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity)
C2U40_20860	ENOG4105YKK	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions (By similarity)
C2U40_20865	ENOG4108ZKU	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions (By similarity)
C2U40_20870	ENOG4108ZAT	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE (By similarity)
C2U40_20875	ENOG4105KME	endoribonuclease L-psp
C2U40_20880	ENOG4105WWK	YheO domain protein
C2U40_20885	ENOG4105D27	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
C2U40_20890	ENOG4108IIJ	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
C2U40_20895	ENOG4105KBC	Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity)
C2U40_20900	ENOG4108VZM	50s ribosomal protein L10
C2U40_20905	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
C2U40_20910	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
C2U40_20915	ENOG4105E5V	Participates in transcription elongation, termination and antitermination (By similarity)
C2U40_20920	ENOG4105PM1	preprotein translocase subunit SecE
C2U40_20930	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
C2U40_20945	ENOG4105CS9	pantothenic acid kinase
C2U40_20950	ENOG4105HJX	Biotin- acetyl-CoA-carboxylase ligase
C2U40_20955	ENOG4105D4A	Cell wall formation (By similarity)
C2U40_20960	ENOG4107ZYR	domain protein
C2U40_20970	ENOG4105E7U	AraC family transcriptional regulator
C2U40_20985	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
C2U40_20990	ENOG4105CUW	cytochrome C-TYPE protein
C2U40_20995	ENOG4107QY8	reductase
C2U40_21005	ENOG4105IFJ	Histidine kinase
C2U40_21010	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
C2U40_21025	ENOG4105DQ2	Is probably involved in the electron transfer between its heme and the molybdenum cofactor of the reductase catalytic subunit YedY (By similarity)
C2U40_21040	ENOG4108UQ5	membrane protein YcdZ
C2U40_21045	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
C2U40_21055	ENOG4107WP9	Histidine kinase
C2U40_21070	ENOG410642E	Short chain dehydrogenase
C2U40_21075	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
C2U40_21090	ENOG4108VVK	transcriptional Regulator, AsnC
C2U40_21095	ENOG4105CU9	asparagine synthetase A
C2U40_21105	ENOG4107T8T	UPF0173 metal-dependent hydrolase
C2U40_21110	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
C2U40_21115	ENOG4105DBW	Multi-copper polyphenol oxidoreductase laccase
C2U40_21120	ENOG4105C34	Pseudouridine synthase
C2U40_21125	ENOG4106SNF	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
C2U40_21130	ENOG4107QMW	pyridine nucleotide-disulfide oxidoreductase
C2U40_21140	ENOG4105CEM	UPF0597 protein
C2U40_21150	ENOG4105C15	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
C2U40_21155	ENOG4108IIE	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
C2U40_21160	ENOG4108I6A	alcohol dehydrogenase
C2U40_21175	ENOG4105R8V	Transcriptional regulator
C2U40_21185	ENOG4108WTW	DNA transposition protein
C2U40_21415	ENOG4105QNF	Outer membrane lipoprotein
C2U40_21420	ENOG4105C8Q	Methyl-accepting chemotaxis
C2U40_21425	ENOG4105DJ4	phosphatidylserine decarboxylase
C2U40_21440	ENOG4105CXT	aspartate transcarbamylase
C2U40_21445	ENOG4108R9M	Involved in allosteric regulation of aspartate carbamoyltransferase (By similarity)
C2U40_21450	ENOG410682Y	Regulates arginine biosynthesis genes (By similarity)
C2U40_21455	ENOG4105CSX	c4-dicarboxylate anaerobic carrier
C2U40_21460	ENOG4105DBV	ornithine carbamoyltransferase
C2U40_21465	ENOG4105C5B	carbamate kinase
C2U40_21485	ENOG4105C8Q	Methyl-accepting chemotaxis
C2U40_21490	ENOG4107SDZ	Galactoside transport system permease protein mglC
C2U40_21505	ENOG4105CNT	hydrolase family 2
C2U40_21510	ENOG41060NJ	transcriptional regulator
C2U40_21515	ENOG4105CMR	udp-glucose 4-epimerase
C2U40_21520	ENOG4105F0Z	galactose-1-phosphate uridylyltransferase
C2U40_21525	ENOG4105CRD	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P) (By similarity)
C2U40_21530	ENOG4105ENN	converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose (By similarity)
C2U40_21535	ENOG4105CPC	Aldo Keto reductase
C2U40_21540	ENOG4105DWR	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity)
C2U40_21545	ENOG4108NIX	Factor ChrR
C2U40_21550	ENOG4105K6V	RNA polymerase
C2U40_21560	ENOG4105C75	arginyL-tRNA synthetase
C2U40_21570	ENOG4108R5P	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery (By similarity)
C2U40_21575	ENOG4105C4N	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis (By similarity)
C2U40_21580	ENOG4105C57	major facilitator superfamily
C2U40_21595	ENOG4105D0S	secretion protein (HlyD
C2U40_21600	ENOG4105CJ1	ABC, transporter
C2U40_21605	ENOG4107QWP	ABC-2 type transporter
C2U40_21610	ENOG4107QWP	ABC-2 type transporter
C2U40_21615	ENOG4107QZF	nitrite reductase NADPH large subunit
C2U40_21620	ENOG4105WZK	nitrite reductase NADPH small subunit
C2U40_21625	ENOG4107V9H	nitrite transporter
C2U40_21630	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
C2U40_21635	ENOG4105CJW	magnesium transporter
C2U40_21640	ENOG4108YYX	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. Modulates RNA-binding and helicase activities of the degradosome (By similarity)
C2U40_21645	ENOG4105EX9	Membrane
C2U40_21655	ENOG4105CNG	UPF0061 protein
C2U40_21660	ENOG4105N7H	Cytochrome
C2U40_21665	ENOG4105C9U	ATP-dependent DNA helicase RecQ
C2U40_21670	ENOG4108VUY	thioesterase Superfamily protein
C2U40_21685	ENOG4108RPX	mosc domain containing protein
C2U40_21690	ENOG4105D38	putrescine abc transporter
C2U40_21695	ENOG4105F38	ABC transporter, permease
C2U40_21700	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
C2U40_21705	ENOG4108HM4	ABC transporter
C2U40_21715	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
C2U40_21720	ENOG4105CFQ	glutamine synthetase
C2U40_21725	ENOG4108V7X	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
C2U40_21740	ENOG4108RH0	Crea protein
C2U40_21745	ENOG4105C5I	Dehydrogenase
C2U40_21750	ENOG4105R8A	Heat shock protein
C2U40_21765	ENOG4107R28	alpha amylase, catalytic region
C2U40_21770	ENOG4105C5E	polysaccharide biosynthesis protein
C2U40_21775	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
C2U40_21785	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
C2U40_21790	ENOG4105P12	pyruvate phosphate dikinase
C2U40_21800	ENOG4107UCJ	Catalyzes the synthesis of activated sulfate (By similarity)
C2U40_21815	ENOG4107T8Q	Glycosyl transferase (Group 1
C2U40_21825	ENOG4105CND	Glycosyl transferase, family 2
C2U40_21840	ENOG4105CEY	Amp-dependent synthetase and ligase
C2U40_21845	ENOG4105CHR	reductase
C2U40_21860	ENOG4105F0R	Cytidylyltransferase
C2U40_21870	ENOG4105D2T	synthase
C2U40_21890	ENOG4105EQQ	protein containing aminopeptidase domain
C2U40_21925	ENOG4107R9T	Catalyzes the formation of 5-methyl-uridine at position 54 (m5U54) in all tRNAs (By similarity)
C2U40_21930	ENOG4107EXC	regulatoR
C2U40_21935	ENOG4105JJR	Histidine kinase
C2U40_21945	ENOG4105C6K	Malic enzyme
C2U40_21950	ENOG4105CGD	Nad-dependent epimerase dehydratase
C2U40_21955	ENOG4105VFB	Binds the 23S rRNA (By similarity)
C2U40_21960	ENOG4105C25	Primosomal protein n'
C2U40_21970	ENOG4105UYK	outer membrane protein a
C2U40_21975	ENOG4105C7B	Threonine dehydratase
C2U40_21980	ENOG4105C01	Dihydroxy-acid dehydratase
C2U40_21985	ENOG4105CM2	brancheD-chain amino acid aminotransferase
C2U40_21990	ENOG4105P3Y	Acetolactate synthase 2 regulatory subunit
C2U40_22005	ENOG4105C0P	Mg chelatase subunit ChlI
C2U40_22010	ENOG4106HNH	Acyl-transferase
C2U40_22015	ENOG4106HNH	Acyl-transferase
C2U40_22020	ENOG4105EWC	Purine nucleoside phosphorylase
C2U40_22030	ENOG4108RWI	nicotinamidase
C2U40_22035	ENOG4107RH7	Nicotinate phosphoribosyltransferase
C2U40_22040	ENOG4108Z33	Thiol disulfide Interchange Protein
C2U40_22045	ENOG4105E27	serine threonine protein kinase
C2U40_22055	ENOG4105PC1	Conserved Protein
C2U40_22075	ENOG4107QP2	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
C2U40_22080	ENOG4105ED0	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates (By similarity)
C2U40_22085	ENOG4105DSJ	YicC domain protein
C2U40_22105	ENOG4105W1T	Glycosyl Transferase
C2U40_22120	ENOG4105CUI	Catalyzes the interconversion between ADP-D-glycero- beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose (By similarity)
C2U40_22125	ENOG41062JF	Transcriptional regulator
C2U40_22130	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
C2U40_22135	ENOG4105CPQ	Dehydrogenase
C2U40_22140	ENOG4105MPD	Cytochrome
C2U40_22145	ENOG4105BZU	Histidine kinase
C2U40_22150	ENOG4105C4R	Atp-dependent dna helicase
C2U40_22155	ENOG4105C9B	Cysteine desulfurase
C2U40_22160	ENOG4105P9C	Participates in cysteine desulfuration mediated by SufS. Cysteine desulfuration mobilizes sulfur from L-cysteine to yield L-alanine and constitutes an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules. Functions as a sulfur acceptor for SufS, by mediating the direct transfer of the sulfur atom from the S-sulfanylcysteine of SufS, an intermediate product of cysteine desulfuration process (By similarity)
C2U40_22165	ENOG4105CUZ	uba thif-type nad fad binding protein
C2U40_22195	ENOG4108RR8	protoporphyrinogen oxidase
C2U40_22200	ENOG4105D37	Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA (By similarity)
C2U40_22205	ENOG4108ZK7	protein family UPF0029, Impact, N-terminal protein
C2U40_22210	ENOG4105D9Y	Splits dipeptides with a prolyl residue in the C- terminal position (By similarity)
C2U40_22215	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
C2U40_22220	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
C2U40_22225	ENOG4105CHU	acetyl-coa acetyltransferase
C2U40_22230	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
C2U40_22235	ENOG4105E0F	Histidine kinase
C2U40_22250	ENOG41082K8	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Interacts with IscS and stimulates its activity. Then, accepts a sulfur from IscS and transfers it in turn to TusD (By similarity)
C2U40_22255	ENOG4105M4H	endoribonuclease L-psp
C2U40_22260	ENOG4108ZG0	Ompa motb domain protein
C2U40_22265	ENOG4105C8Q	Methyl-accepting chemotaxis
C2U40_22270	ENOG4108R3E	Dna-3-methyladenine glycosylase i
C2U40_22275	ENOG4108HMW	glycyl-tRNA synthetase, alpha subunit
C2U40_22280	ENOG4105C38	Glycyl-tRNA synthetase beta subunit
C2U40_22315	ENOG41072JS	exoenzyme T
C2U40_22325	ENOG4105VNT	transposase (IS4 family) protein
C2U40_22335	ENOG4105CIC	tryptophan-specific transport protein
C2U40_22340	ENOG4105HEE	Binding Domain protein
C2U40_22350	ENOG4108EQM	faD-dependent pyridine nucleotide-disulfide oxidoreductase
C2U40_22355	ENOG4105CNW	domain protein
C2U40_22360	ENOG4108JUA	Transcriptional regulator
C2U40_22365	ENOG4105FDP	GntR family transcriptional regulator
C2U40_22370	ENOG4105CI1	PTS System
C2U40_22375	ENOG4105F8D	glycoside hydrolase family 4
C2U40_22380	ENOG4105ETE	Transcriptional regulator (LacI family
C2U40_22385	ENOG4105CP9	extracellular ligand-binding receptor
C2U40_22390	ENOG4105C32	Amino acid ABC transporter (Permease)
C2U40_22395	ENOG4105CF8	branched-chain amino acid ABC transporter, permease
C2U40_22400	ENOG4105C0Z	ABC transporter
C2U40_22405	ENOG4108IV0	ABC, transporter
C2U40_22420	ENOG4105M78	Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide (By similarity)
C2U40_22435	ENOG4105W0Z	cytoplasmic protein
C2U40_22440	ENOG4107QK7	reductase
C2U40_22445	ENOG4105D3H	Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol (By similarity)
C2U40_22455	ENOG4105C4P	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity)
C2U40_22460	ENOG4105K63	Thioredoxin
C2U40_22465	ENOG4105C1J	atp-dependent rna helicase
C2U40_22470	ENOG4105C9X	ppx gppa phosphatase
C2U40_22485	ENOG4105FFN	Specifically methylates the guanosine in position 1516 of 16S rRNA (By similarity)
C2U40_22490	ENOG4105BZU	Histidine kinase
C2U40_22495	ENOG4105DGW	oligopeptidase A
C2U40_22500	ENOG4105D52	delta-aminolevulinic acid dehydratase
C2U40_22505	ENOG4105F8V	Hydrolase, tatD family
C2U40_22510	ENOG4105DCX	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity)
C2U40_22515	ENOG4105X8U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation (By similarity)
C2U40_22520	ENOG4105WKS	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity)
C2U40_22525	ENOG4105CNK	Required, probably indirectly, for the hydroxylation of 2-octaprenylphenol to 2-octaprenyl-6-hydroxy-phenol, the fourth step in ubiquinone biosynthesis (By similarity)
C2U40_22530	ENOG4105JC1	sterol-binding domain protein
C2U40_22540	ENOG4105WMR	Protein CrcB homolog
C2U40_22545	ENOG4105DZC	cytosine deaminase
C2U40_22585	ENOG410822N	TonB family
C2U40_22590	ENOG4109015	Biopolymer transport protein exbD tolR
C2U40_22610	ENOG4105VJY	transcriptional regulator
C2U40_22615	ENOG4105DZR	Type I site-specific deoxyribonuclease
C2U40_22635	ENOG4105EKX	Restriction modification system DNA (Specificity
C2U40_22640	ENOG4105CVR	type I restriction-modification system
C2U40_22675	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
C2U40_22680	ENOG410804X	Transcriptional regulator
C2U40_22685	ENOG4105E3W	Two component transcriptional regulator (Winged helix family
C2U40_22690	ENOG4105EB3	Histidine kinase
C2U40_22700	ENOG4105CT7	inner membrane cred family protein
C2U40_22705	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
C2U40_22710	ENOG4105KNM	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
C2U40_22715	ENOG4105C4J	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity)
C2U40_22720	ENOG4105J80	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity)
C2U40_22725	ENOG4105CDG	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity)
C2U40_22730	ENOG4107S15	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
C2U40_22735	ENOG4107Z6K	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
C2U40_22740	ENOG4105KY6	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
C2U40_22745	ENOG4105EE4	it plays a direct role in the translocation of protons across the membrane (By similarity)
C2U40_22755	ENOG4105FA0	parb-like partition protein
C2U40_22760	ENOG4107QJE	Chromosome Partitioning Protein
C2U40_22765	ENOG4105D28	Specifically methylates the N7 position of a guanine in 16S rRNA (By similarity)
C2U40_22770	ENOG4107RE5	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity)
C2U40_22775	ENOG4105QTB	Flavodoxin
C2U40_22780	ENOG4105E0K	tonB-dependent siderophore receptor
C2U40_22785	ENOG4105IBP	Cyclic peptide transporter
C2U40_22790	ENOG4105E0A	ABC, transporter
C2U40_22800	ENOG4105S6R	Iron-hydroxamate transporter permease subunit
C2U40_22810	ENOG4105CAF	HipA N-terminal domain protein
C2U40_22835	ENOG4105D70	Integrase catalytic subunit
C2U40_22840	ENOG4105F5W	AtP-binding protein
C2U40_22905	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
C2U40_22910	ENOG4105C1H	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity)
C2U40_22915	ENOG4105DHW	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
C2U40_22920	ENOG4105VAS	Could be involved in insertion of integral membrane proteins into the membrane (By similarity)
C2U40_22925	ENOG4105NVJ	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme (By similarity)
C2U40_22930	ENOG4105VG0	50S ribosomal protein l34
C2U40_22935	ENOG4105CDA	abc transporter atp-binding protein
C2U40_22940	ENOG4105E5Q	amino acid AbC transporter
C2U40_22945	ENOG4105EAB	amino acid AbC transporter
C2U40_22950	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
C2U40_22955	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
C2U40_22960	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
C2U40_22965	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
C2U40_22980	ENOG4108ZNX	Heat shock protein
C2U40_22985	ENOG4108ZNX	Heat shock protein
C2U40_22990	ENOG4105JKW	Valine--pyruvate aminotransferase
C2U40_23005	ENOG4105C2C	drug resistance transporter, Bcr CflA
C2U40_23010	ENOG4105EEX	Two component transcriptional regulator (Winged helix family
C2U40_23015	ENOG4105C08	Histidine kinase
C2U40_23025	ENOG4105C8X	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity)
C2U40_23030	ENOG4105D9K	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity)
C2U40_23040	ENOG4105DC8	reductase
C2U40_23045	ENOG4105BZU	Histidine kinase
C2U40_23050	ENOG4105BZS	acriflavin resistance protein
C2U40_23055	ENOG410624X	efflux transporter, rnd family, mfp subunit
C2U40_23090	ENOG4105DQF	Hydrolase
C2U40_23095	ENOG4108EUD	Lysophospholipase
C2U40_23100	ENOG4105FE8	tRNA (Guanosine-2'-O-)-methyltransferase
C2U40_23105	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
C2U40_23110	ENOG4105VFG	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity)
C2U40_23120	ENOG4105DKP	glycosyl transferase, family 9
C2U40_23125	ENOG4108W7E	Catalyzes the ATP-dependent phosphorylation of the 3- deoxy-D-manno-octulosonic acid (Kdo) residue in Kdo-lipid IV(A) at the 4-OH position (By similarity)
C2U40_23135	ENOG4105EMK	carboxylate amino acid amine transporter
C2U40_23165	ENOG4108M6U	Universal stress protein A
C2U40_23170	ENOG4105RKW	reductase (By
C2U40_23175	ENOG4105BZU	Histidine kinase
C2U40_23180	ENOG41090A1	ferritin
C2U40_23185	ENOG4105CBX	hi0933 family
C2U40_23190	ENOG4105EU0	Major facilitator Superfamily
C2U40_23210	ENOG4108N3D	putative enzyme
C2U40_23215	ENOG4108NN8	Fimbrial protein
C2U40_23220	ENOG4108GWT	fimbrillin MatB
C2U40_23225	ENOG4107ZHV	Transcriptional regulator
C2U40_23230	ENOG4105BZU	Histidine kinase
C2U40_23240	ENOG4108HRK	Histidine kinase
C2U40_23245	ENOG4105DY9	regulatoR
C2U40_23250	ENOG4105FCD	Major Facilitator
C2U40_23255	ENOG4105CY8	phosphoribosylaminoimidazole carboxylase atpase subunit
C2U40_23260	ENOG4108UM6	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity)
C2U40_23275	ENOG41063Z6	transcriptional regulator, lysR family
C2U40_23280	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
C2U40_23285	ENOG4105F03	Provides the (R)-glutamate required for cell wall biosynthesis (By similarity)
C2U40_23315	ENOG4105CD5	CoA-binding domain protein
C2U40_23330	ENOG4105EMY	transcriptional regulator
C2U40_23335	ENOG4105C6M	Alpha-keto-beta-hydroxylacyl reductoisomerase
C2U40_23340	ENOG4107QP8	phosphohexose isomerase
C2U40_23355	ENOG4105D64	Mechanosensitive ion channel
C2U40_23360	ENOG4105EC0	Required for nucleoid occlusion (NO) phenomenon, which prevents Z-ring formation and cell division over the nucleoid. Acts as a DNA-associated cell division inhibitor that binds simultaneously chromosomal DNA and FtsZ, and disrupts the assembly of FtsZ polymers. SlmA-DNA-binding sequences (SBS) are dispersed on non-Ter regions of the chromosome, preventing FtsZ polymerization at these regions (By similarity)
C2U40_23365	ENOG4108Z1K	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA (By similarity)
C2U40_23370	ENOG4105CJS	Phosphopantothenoylcysteine decarboxylase
C2U40_23375	ENOG4105W5Q	DNA repair protein (RadC
C2U40_23380	ENOG4105KDC	50s ribosomal protein l28
C2U40_23385	ENOG4105W0E	50S ribosomal protein L33
C2U40_23395	ENOG4105ERD	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity)
C2U40_23400	ENOG4108MJ5	VirK protein
C2U40_23405	ENOG4108ZEF	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity)
C2U40_23410	ENOG4105M5K	heptosyltransferase
C2U40_23415	ENOG4106WTF	Glycosyl transferase, family 2
C2U40_23420	ENOG4105XA0	heptosyltransferase ii
C2U40_23425	ENOG4105D8A	3-Deoxy-D-manno-octulosonic-acid transferase
C2U40_23445	ENOG4105DIQ	Transcriptional regulator
C2U40_23450	ENOG4105D3Z	quinone oxidoreductase, yhdh yhfp family
C2U40_23470	ENOG4105X6C	Flagellar basal body-associated protein FliL
C2U40_23475	ENOG4105VEI	Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4- hydroxybenzoate (4HB) for the ubiquinone pathway (By similarity)
C2U40_23480	ENOG4105C4G	Synthesis of 3-octaprenyl-4-hydroxybenzoate (By similarity)
C2U40_23485	ENOG4105E55	glycerol-3-phosphate acyltransferase
C2U40_23490	ENOG4105DS7	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity)
C2U40_23515	ENOG4107R73	Mate efflux family protein
C2U40_23520	ENOG4108UIQ	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity)
C2U40_23525	ENOG4105E0F	Histidine kinase
C2U40_23530	ENOG4105E3W	Two component transcriptional regulator (Winged helix family
C2U40_23540	ENOG4105D7W	serine acetyltransferase
C2U40_23550	ENOG41065UX	Non-essential, abundant cell division factor that is required for proper Z-ring formation. It is recruited early to the divisome by direct interaction with FtsZ, stimulating Z-ring assembly and thereby promoting cell division earlier in the cell cycle. Its recruitment to the Z-ring requires functional FtsA or ZipA (By similarity)
C2U40_23555	ENOG4108556	Isoprenoid biosynthesis protein with amidotransferase-like domain
C2U40_23565	ENOG4105C2M	dna polymerase I
C2U40_23570	ENOG4108Z0R	Transferase
C2U40_23610	ENOG4105CQ4	Transcriptional regulator
C2U40_23615	ENOG4105CNT	hydrolase family 2
C2U40_23620	ENOG4105FK9	beta-D-galactosidase beta subunit
C2U40_23625	ENOG4105E5D	amino acid
C2U40_23630	ENOG4108Y51	tRNA-binding protein
C2U40_23635	ENOG4105E5D	amino acid
C2U40_23640	ENOG4105DHU	Bile acid
C2U40_23645	ENOG4105E46	N-alpha,N-alpha,N-alpha-trimethyl-L-histidine metabolic process
C2U40_23665	ENOG4105CC0	LysR family Transcriptional regulator
C2U40_23675	ENOG4105UIB	(ABC) transporter
C2U40_23680	ENOG4108JQ9	ABC transporter
C2U40_23685	ENOG4105DIH	basic membrane
C2U40_23690	ENOG4105C4R	Atp-dependent dna helicase
C2U40_23700	ENOG4108UK5	Transposase
C2U40_23705	ENOG4105HEI	LysR family (Transcriptional regulator
C2U40_23725	ENOG41061EV	selenium-binding protein YdfZ
C2U40_23750	ENOG4108YH8	Covalently attaches a chromophore to Cys residue(s) of phycobiliproteins (By similarity)
C2U40_23760	ENOG410829K	Lysine exporter protein (Lyse ygga)
C2U40_23770	ENOG4105CUC	YeeE YedE family protein
C2U40_23775	ENOG4105C8Q	Methyl-accepting chemotaxis
C2U40_23780	ENOG4105C52	Atpase, p-type (Transporting), had superfamily, subfamily ic
C2U40_23790	ENOG4105ECQ	AraC Family Transcriptional Regulator
C2U40_23795	ENOG4105FR1	rard protein
C2U40_23805	ENOG4105C26	Dehydrogenase
C2U40_23810	ENOG4108JCI	Transcriptional regulator
C2U40_23820	ENOG4105C26	Dehydrogenase
C2U40_23825	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
C2U40_23830	ENOG4105DCF	alanine dehydrogenase
C2U40_23835	ENOG4108MGF	sugar kinase
C2U40_23855	ENOG4105CGY	Dna recombination protein
C2U40_23860	ENOG4105D37	Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA (By similarity)
C2U40_23865	ENOG4105C1A	potassium transporter peripheral membrane
C2U40_23870	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
C2U40_23875	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
C2U40_23880	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
C2U40_23890	ENOG4105C79	DNA protecting protein DprA
C2U40_23895	ENOG4108RPN	Protein smg homolog
C2U40_23900	ENOG4108WI1	Dna topoisomerase
C2U40_23910	ENOG4105EK0	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
C2U40_23915	ENOG4105DBS	Key enzyme in heme biosynthesis. Catalyzes the oxidative decarboxylation of propionic acid side chains of rings A and B of coproporphyrinogen III (By similarity)
C2U40_23920	ENOG4105E2X	shikimate dehydrogenase
C2U40_23925	ENOG4105SG3	Protein of unknown function (DUF1488)
C2U40_23930	ENOG4105WHM	Necessary for normal cell division and for the maintenance of normal septation (By similarity)
C2U40_23935	ENOG4106RE7	Cytochrome
C2U40_23945	ENOG4105ZR3	A GTPase-activating protein (GAP) that modifies Der EngA GTPase function. May play a role in ribosome biogenesis (By similarity)
C2U40_23950	ENOG4105XCT	Protein of unknown function (DUF2489)
C2U40_23955	ENOG4105D4P	Coproporphyrinogen iii oxidase
C2U40_23960	ENOG4105EKD	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism (By similarity)
C2U40_23965	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
C2U40_23970	ENOG4105CUX	Signal transduction histidine kinase
C2U40_23980	ENOG4105C5F	glutamine synthetase
C2U40_23995	ENOG4107S2Z	UPF0761 membrane protein
C2U40_24000	ENOG4108YYA	Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine (By similarity)
C2U40_24010	ENOG4105SUU	thioesterase domain
C2U40_24020	ENOG4105CB5	ATP-dependent DNA helicase recG
C2U40_24025	ENOG4105JIM	Phosphatidylserine synthase
C2U40_24030	ENOG4105C6Z	Gluconate
C2U40_24035	ENOG4108Z67	carbohydrate kinase, thermoresistant glucokinase family
C2U40_24040	ENOG4105C01	Dihydroxy-acid dehydratase
C2U40_24045	ENOG4108UHU	Aldolase
C2U40_24050	ENOG4105DIQ	Transcriptional regulator
C2U40_24060	ENOG41063SB	peptidase
C2U40_24065	ENOG4105CJI	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
C2U40_24070	ENOG4107YZP	Rhodanese domain protein
C2U40_24075	ENOG4105IX2	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA (By similarity)
C2U40_24080	ENOG4105CSF	NADPH-dependent glycerol-3-phosphate dehydrogenase
C2U40_24085	ENOG4107RUK	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins (By similarity)
C2U40_24090	ENOG4105MJ2	Competence protein
C2U40_24095	ENOG4105D3C	The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters (By similarity)
C2U40_24115	ENOG4105BZM	domain protein
C2U40_24120	ENOG4108RRZ	Transcription elongation factor GreB
C2U40_24125	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
C2U40_24130	ENOG4105E0F	Histidine kinase
C2U40_24140	ENOG4108Z10	Involved in the binding of tRNA to the ribosomes (By similarity)
C2U40_24145	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
C2U40_24150	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
C2U40_24155	ENOG41080KG	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
C2U40_24160	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
C2U40_24165	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
C2U40_24170	ENOG4105KAP	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity)
C2U40_24175	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
C2U40_24180	ENOG4108R70	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity)
C2U40_24185	ENOG41083MP	50s ribosomal protein l29
C2U40_24190	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
C2U40_24195	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
C2U40_24200	ENOG4105KAR	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity)
C2U40_24205	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
C2U40_24210	ENOG4105VBI	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
C2U40_24215	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
C2U40_24220	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
C2U40_24225	ENOG4105K4C	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity)
C2U40_24230	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
C2U40_24235	ENOG4105VPB	50S ribosomal protein L30
C2U40_24240	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
C2U40_24245	ENOG4105CGG	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity)
C2U40_24250	ENOG41067V7	50S ribosomal protein L36
C2U40_24255	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
C2U40_24260	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
C2U40_24265	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
C2U40_24270	ENOG4105CTF	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
C2U40_24275	ENOG4108ZT0	50S ribosomal protein l17
C2U40_24335	ENOG4108K2R	Glutathione-regulated potassium-efflux system ancillary protein
C2U40_24340	ENOG4108W5M	transcriptional regulator
C2U40_24345	ENOG4105EMU	Dehydrogenase
C2U40_24360	ENOG4105CUG	Oligopeptidase b
C2U40_24385	ENOG4107FS9	Membrane
C2U40_24400	ENOG4105JQN	Transcriptional regulator
C2U40_24415	ENOG4105VVZ	metal-binding protein
C2U40_24420	ENOG41076UM	multiple antibiotic resistance (MarC)-related protein
C2U40_24430	ENOG4105WKS	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity)
C2U40_24440	ENOG4105E4C	Lytic transglycosylase catalytic
C2U40_24445	ENOG4107RZC	phospholipase d
C2U40_24460	ENOG4105EJ2	Transcriptional regulator
C2U40_24465	ENOG4108Y73	Membrane
C2U40_24475	ENOG4106H78	methyltransferase
C2U40_24480	ENOG4105CCP	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
C2U40_24485	ENOG4105CAK	Cell division ATP-binding protein ftsE
C2U40_24490	ENOG4105CRP	Part of the ABC transporter FtsEX involved in
C2U40_24500	ENOG41077A9	carbonic anhydrase
C2U40_24505	ENOG4105CZE	histidine utilization repressor
C2U40_24510	ENOG4105CI2	imidazolone-5-propionate hydrolase
C2U40_24515	ENOG41088SP	formiminoglutamate hydrolase
C2U40_24520	ENOG4105CGP	Urocanate hydratase
C2U40_24525	ENOG4105C84	Histidine ammonia-lyase
C2U40_24530	ENOG4105EWV	Sodium calcium exchanger membrane region
C2U40_24535	ENOG4107XTP	(EAL) domain protein
C2U40_24540	ENOG41062P1	Diguanylate cyclase phosphodiesterase
C2U40_24580	ENOG4108C33	Resolvase
C2U40_24715	ENOG4108IRC	dna polymerase iii
C2U40_24835	ENOG4107SKI	cobyrinic Acid a,c-diamide synthase
C2U40_24845	ENOG4105K4U	addiction module toxin, RelE StbE family
C2U40_24880	ENOG4105C26	Dehydrogenase
C2U40_24915	ENOG4105D13	transposase
C2U40_24960	ENOG4108IRC	dna polymerase iii
C2U40_25005	ENOG4105D13	transposase
C2U40_25030	ENOG4108C33	Resolvase
C2U40_25130	ENOG4107RHT	methyl-accepting chemotaxis sensory transducer with Pas Pac sensor
C2U40_25210	ENOG4107RHT	methyl-accepting chemotaxis sensory transducer with Pas Pac sensor
C2U40_25245	ENOG4105VNT	transposase (IS4 family) protein
C2U40_25370	ENOG4105BZU	Histidine kinase
C2U40_25465	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
C2U40_25520	ENOG4108YX2	DNA-binding protein
C2U40_25550	ENOG4107QHF	type ii secretion system protein e
C2U40_25875	ENOG4105KT5	UmuD protein