locus-tag	class	description
HUI97_00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
HUI97_00010	COG0592	DNA-directed DNA polymerase activity
HUI97_00020	COG0187	DNA topoisomerase II activity
HUI97_00030	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
HUI97_00035	COG0071	Belongs to the small heat shock protein (HSP20) family
HUI97_00040	COG0071	Belongs to the small heat shock protein (HSP20) family
HUI97_00045	COG3977	Valine--pyruvate aminotransferase
HUI97_00060	COG2814	Major facilitator Superfamily
HUI97_00065	COG0745	RESPONSE REGULATOR receiver
HUI97_00070	COG2205	protein histidine kinase activity
HUI97_00090	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
HUI97_00095	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HUI97_00095	COG4191	Histidine kinase
HUI97_00105	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HUI97_00110	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HUI97_00115	COG1309	transcriptional regulator
HUI97_00145	COG0469	pyruvate kinase activity
HUI97_00150	COG2271	Major facilitator Superfamily
HUI97_00175	COG0561	phosphatase activity
HUI97_00180	COG2267	carboxylic ester hydrolase activity
HUI97_00185	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HUI97_00190	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HUI97_00195	COG1758	RNA polymerase activity
HUI97_00200	COG0194	GDP metabolic process
HUI97_00205	COG0859	PFAM glycosyl transferase family 9
HUI97_00210	COG3642	lipopolysaccharide core region biosynthetic process
HUI97_00250	COG0589	response to stress
HUI97_00255	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
HUI97_00260	COG1528	Iron-storage protein
HUI97_00265	COG2081	HI0933 family
HUI97_00270	COG3275	phosphorelay sensor kinase activity
HUI97_00275	COG3279	Response regulator of the LytR AlgR family
HUI97_00280	COG2223	nitrite transmembrane transporter activity
HUI97_00285	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
HUI97_00290	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
HUI97_00305	COG0583	DNA-binding transcription factor activity
HUI97_00310	COG4206	TonB-dependent receptor
HUI97_00345	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
HUI97_00350	COG2166	iron-sulfur cluster assembly
HUI97_00355	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
HUI97_00370	COG3245	cytochrome
HUI97_00375	COG1063	alcohol dehydrogenase
HUI97_00390	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
HUI97_00400	COG3307	-O-antigen
HUI97_00410	COG0562	UDP-galactopyranose mutase
HUI97_00430	COG0166	Belongs to the GPI family
HUI97_00435	COG0668	transmembrane transport
HUI97_00440	COG1309	transcriptional regulator
HUI97_00445	COG0756	dUTP diphosphatase activity
HUI97_00450	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
HUI97_00455	COG2003	Belongs to the UPF0758 family
HUI97_00460	COG0227	Belongs to the bacterial ribosomal protein bL28 family
HUI97_00465	COG0267	Belongs to the bacterial ribosomal protein bL33 family
HUI97_00475	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
HUI97_00480	COG2990	Protein conserved in bacteria
HUI97_00485	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
HUI97_00490	COG0859	PFAM glycosyl transferase family 9
HUI97_00495	COG0463	Glycosyl transferase, family 2
HUI97_00500	COG0859	PFAM glycosyl transferase family 9
HUI97_00505	COG1519	Transferase
HUI97_00510	COG0604	alcohol dehydrogenase
HUI97_00530	COG3161	chorismate lyase activity
HUI97_00535	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
HUI97_00540	COG2937	Belongs to the GPAT DAPAT family
HUI97_00545	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
HUI97_00560	COG0534	Mate efflux family protein
HUI97_00565	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
HUI97_00570	COG2205	protein histidine kinase activity
HUI97_00575	COG0745	RESPONSE REGULATOR receiver
HUI97_00585	COG1045	serine acetyltransferase
HUI97_00595	COG3074	FtsZ-dependent cytokinesis
HUI97_00600	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
HUI97_00605	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HUI97_00605	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HUI97_00610	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
HUI97_00645	COG1609	Transcriptional regulator
HUI97_00650	COG3250	beta-galactosidase activity
HUI97_00655	COG2731	YhcH YjgK YiaL family protein
HUI97_00660	COG0531	amino acid
HUI97_00665	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HUI97_00670	COG0531	amino acid
HUI97_00675	COG0385	Bile acid
HUI97_00700	COG0583	DNA-binding transcription factor activity
HUI97_00705	COG1561	YicC-like family, N-terminal region
HUI97_00710	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
HUI97_00715	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
HUI97_00730	COG5001	Diguanylate cyclase
HUI97_00730	COG2203	Gaf domain
HUI97_00730	COG4251	negative regulation of phosphorylation
HUI97_00730	COG3706	GGDEF domain
HUI97_00735	COG3084	Protein conserved in bacteria
HUI97_00745	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
HUI97_00750	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
HUI97_00760	COG1335	isochorismatase
HUI97_00770	COG1683	Conserved Protein
HUI97_00775	COG0204	Acyl-transferase
HUI97_00780	COG0204	Acyl-transferase
HUI97_00785	COG0606	chelatase, subunit chli
HUI97_00795	COG3978	acetolactate synthase activity
HUI97_00805	COG0129	dihydroxy-acid dehydratase activity
HUI97_00820	COG2391	methyltransferase activity
HUI97_00825	COG0840	transmembrane signaling receptor activity
HUI97_00830	COG2962	Rard protein
HUI97_00840	COG1012	belongs to the aldehyde dehydrogenase family
HUI97_00845	COG1396	sequence-specific DNA binding
HUI97_00850	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
HUI97_00860	COG0519	Catalyzes the synthesis of GMP from XMP
HUI97_00860	COG0518	GMP synthase (glutamine-hydrolyzing) activity
HUI97_00865	COG0583	DNA-binding transcription factor activity
HUI97_00870	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HUI97_00890	COG1322	Protein conserved in bacteria
HUI97_00895	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
HUI97_00900	COG2204	response regulator
HUI97_00905	COG3852	Histidine kinase
HUI97_00915	COG0174	glutamine synthetase
HUI97_00920	COG1217	gtp-binding protein TYPA
HUI97_00925	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
HUI97_00930	COG0569	domain protein
HUI97_00935	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
HUI97_00935	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
HUI97_00940	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
HUI97_00945	COG0242	peptide deformylase activity
HUI97_00950	COG1652	LysM domain
HUI97_00955	COG0758	DNA mediated transformation
HUI97_00960	COG2922	Belongs to the Smg family
HUI97_00965	COG0551	DNA topoisomerase type I activity
HUI97_00975	COG0009	L-threonylcarbamoyladenylate synthase
HUI97_00980	COG0408	coproporphyrinogen oxidase activity
HUI97_00985	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
HUI97_00995	COG0218	Necessary for normal cell division and for the maintenance of normal septation
HUI97_01005	COG3078	GTPase activator activity
HUI97_01015	COG0635	Involved in the biosynthesis of porphyrin-containing compound
HUI97_01045	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
HUI97_01050	COG1288	antiporter activity
HUI97_01055	COG1438	arginine binding
HUI97_01060	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
HUI97_01065	COG0540	Belongs to the ATCase OTCase family
HUI97_01085	COG0583	DNA-binding transcription factor activity
HUI97_01105	COG2207	Transcriptional regulator
HUI97_01110	COG1979	alcohol dehydrogenase
HUI97_01115	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
HUI97_01120	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
HUI97_01130	COG2964	Protein conserved in bacteria
HUI97_01135	COG3681	Belongs to the UPF0597 family
HUI97_01145	COG0446	pyridine nucleotide-disulphide oxidoreductase
HUI97_01150	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
HUI97_01155	COG0564	pseudouridine synthase activity
HUI97_01165	COG0542	response to heat
HUI97_01170	COG2502	aspartate--ammonia ligase
HUI97_01175	COG1522	sequence-specific DNA binding
HUI97_01185	COG5413	integral membrane protein
HUI97_01190	COG0516	GMP reductase activity
HUI97_01190	COG0517	IMP dehydrogenase activity
HUI97_01195	COG1028	Short-chain dehydrogenase reductase Sdr
HUI97_01210	COG2205	protein histidine kinase activity
HUI97_01220	COG2204	response regulator
HUI97_01265	COG0243	molybdopterin cofactor binding
HUI97_01270	COG3005	denitrification pathway
HUI97_01275	COG4191	Histidine kinase
HUI97_01275	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HUI97_01305	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
HUI97_01310	COG0569	domain protein
HUI97_01315	COG0812	UDP-N-acetylmuramate dehydrogenase activity
HUI97_01340	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
HUI97_01355	COG0250	Participates in transcription elongation, termination and antitermination
HUI97_01360	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
HUI97_01365	COG0081	regulation of translation
HUI97_01370	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
HUI97_01375	COG0222	ribosome binding
HUI97_01380	COG0085	RNA polymerase activity
HUI97_01385	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HUI97_01390	COG2964	Protein conserved in bacteria
HUI97_01400	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
HUI97_01405	COG2923	Belongs to the DsrF TusC family
HUI97_01410	COG2168	tRNA wobble position uridine thiolation
HUI97_01415	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
HUI97_01420	COG0049	tRNA binding
HUI97_01425	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
HUI97_01430	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
HUI97_01435	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
HUI97_01485	COG3714	YhhN family
HUI97_01510	COG1301	dicarboxylic acid transport
HUI97_01520	COG2095	MarC family integral membrane protein
HUI97_01530	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
HUI97_01540	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
HUI97_01550	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HUI97_01565	COG1770	oligopeptidase
HUI97_01580	COG4221	oxidoreductase activity
HUI97_01585	COG0583	DNA-binding transcription factor activity
HUI97_01615	COG0742	ribosomal rna small subunit methyltransferase
HUI97_01620	COG0552	protein localization to endoplasmic reticulum
HUI97_01625	COG2884	Cell division ATP-binding protein ftsE
HUI97_01630	COG2177	Part of the ABC transporter FtsEX involved in
HUI97_01640	COG0288	reversible hydration of carbon dioxide
HUI97_01645	COG2188	Transcriptional regulator
HUI97_01650	COG1228	amidohydrolase
HUI97_01655	COG0010	Belongs to the arginase family
HUI97_01660	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
HUI97_01665	COG2986	histidine ammonia-lyase
HUI97_01670	COG0387	Pfam Sodium calcium exchanger
HUI97_01675	COG2200	EAL domain
HUI97_01680	COG2199	diguanylate cyclase activity
HUI97_01680	COG2200	EAL domain
HUI97_01725	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
HUI97_01730	COG1459	type II secretion system
HUI97_01745	COG2165	general secretion pathway protein
HUI97_01750	COG4968	Prepilin-type N-terminal cleavage methylation domain
HUI97_01775	COG1077	Cell shape determining protein MreB Mrl
HUI97_01780	COG1792	Involved in formation and maintenance of cell shape
HUI97_01785	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
HUI97_01790	COG0424	maF-like protein
HUI97_01795	COG1530	ribonuclease E activity
HUI97_01800	COG3164	Protein of unknown function
HUI97_01810	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
HUI97_01815	COG0312	modulator of DNA gyrase
HUI97_01835	COG0477	Major facilitator Superfamily
HUI97_01880	COG0189	ligase activity
HUI97_01885	COG0642	Histidine kinase
HUI97_01890	COG0745	RESPONSE REGULATOR receiver
HUI97_01910	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
HUI97_01915	COG0352	thiamine-phosphate diphosphorylase activity
HUI97_01920	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
HUI97_01930	COG2022	thiamine diphosphate biosynthetic process
HUI97_01935	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
HUI97_01960	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
HUI97_01980	COG0583	DNA-binding transcription factor activity
HUI97_01985	COG1380	Effector of murein hydrolase LrgA
HUI97_01990	COG1346	cytolysis
HUI97_02000	COG4667	esterase of the alpha-beta hydrolase superfamily
HUI97_02005	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
HUI97_02010	COG1546	Belongs to the CinA family
HUI97_02015	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
HUI97_02025	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
HUI97_02030	COG0527	aspartate kinase activity
HUI97_02035	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
HUI97_02070	COG1686	Belongs to the peptidase S11 family
HUI97_02075	COG0586	Pfam SNARE associated Golgi protein
HUI97_02080	COG1253	flavin adenine dinucleotide binding
HUI97_02085	COG0252	asparaginase activity
HUI97_02100	COG1609	Transcriptional regulator
HUI97_02105	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HUI97_02105	COG1263	PTS System
HUI97_02110	COG0366	Alpha amylase catalytic
HUI97_02115	COG0110	maltose O-acetyltransferase activity
HUI97_02125	COG0564	pseudouridine synthase activity
HUI97_02130	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
HUI97_02165	COG2926	Belongs to the UPF0265 family
HUI97_02175	COG0561	phosphatase activity
HUI97_02185	COG1546	Belongs to the CinA family
HUI97_02185	COG1058	Belongs to the CinA family
HUI97_02195	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
HUI97_02205	COG1522	sequence-specific DNA binding
HUI97_02210	COG1368	sulfuric ester hydrolase activity
HUI97_02250	COG4221	oxidoreductase activity
HUI97_02265	COG1979	alcohol dehydrogenase
HUI97_02270	COG1803	Methylglyoxal synthase
HUI97_02290	COG1444	tRNA N-acetyltransferase activity
HUI97_02300	COG0835	chemotaxis
HUI97_02300	COG0784	Response regulator, receiver
HUI97_02310	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
HUI97_02315	COG2949	membrane
HUI97_02320	COG3291	Pkd domain containing protein
HUI97_02340	COG3188	usher protein
HUI97_02345	COG3121	Chaperone
HUI97_02350	COG3539	Fimbrial protein
HUI97_02365	COG3039	Transposase
HUI97_02370	COG3039	Transposase
HUI97_02380	COG1441	menaquinone biosynthetic process
HUI97_02385	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
HUI97_02390	COG0596	Alpha beta hydrolase
HUI97_02395	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
HUI97_02400	COG1169	isochorismate synthase
HUI97_02405	COG1575	Belongs to the MenA family. Type 1 subfamily
HUI97_02425	COG0513	Belongs to the DEAD box helicase family
HUI97_02430	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
HUI97_02435	COG1988	membrane-bound metal-dependent
HUI97_02440	COG1671	Belongs to the UPF0178 family
HUI97_02460	COG0484	heat shock protein binding
HUI97_02470	COG3722	fumarate hydratase activity
HUI97_02475	COG0246	Mannitol dehydrogenase
HUI97_02480	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
HUI97_02480	COG2213	PTS system mannitol-specific
HUI97_02485	COG1560	Kdo2-lipid A biosynthetic process
HUI97_02490	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
HUI97_02490	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
HUI97_02495	COG1538	Outer membrane efflux protein
HUI97_02500	COG0494	nUDIX hydrolase
HUI97_02505	COG3151	Protein conserved in bacteria
HUI97_02515	COG3150	esterase
HUI97_02540	COG3104	oligopeptide transport
HUI97_02580	COG0583	DNA-binding transcription factor activity
HUI97_02585	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
HUI97_02605	COG0204	Acyl-transferase
HUI97_02610	COG1842	Phage shock protein A
HUI97_02625	COG2827	Endonuclease containing a URI domain
HUI97_02640	COG1573	uracil-dna glycosylase
HUI97_02645	COG0697	spore germination
HUI97_02650	COG0583	DNA-binding transcription factor activity
HUI97_02655	COG1108	ABC-type Mn2 Zn2 transport systems permease components
HUI97_02660	COG1121	(ABC) transporter
HUI97_02665	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
HUI97_02685	COG0739	heme binding
HUI97_02695	COG3068	Protein conserved in bacteria
HUI97_02715	COG0617	tRNA 3'-terminal CCA addition
HUI97_02720	COG1194	a g-specific adenine glycosylase
HUI97_02725	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
HUI97_02735	COG3111	PFAM Bacterial OB fold (BOF) protein
HUI97_02740	COG3240	lipase activity
HUI97_02750	COG3706	GGDEF domain
HUI97_02755	COG0557	exoribonuclease II activity
HUI97_02760	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HUI97_02770	COG2153	protein acetylation
HUI97_02775	COG0513	Belongs to the DEAD box helicase family
HUI97_02780	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
HUI97_02805	COG0735	belongs to the Fur family
HUI97_02810	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HUI97_02815	COG0840	transmembrane signaling receptor activity
HUI97_02825	COG4166	transmembrane transport
HUI97_02835	COG0110	maltose O-acetyltransferase activity
HUI97_02845	COG1024	Enoyl-CoA hydratase
HUI97_02860	COG4221	oxidoreductase activity
HUI97_02865	COG0442	prolyl-tRNA aminoacylation
HUI97_02870	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HUI97_02880	COG3008	intermembrane lipid transfer
HUI97_02880	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
HUI97_02885	COG2995	paraquat-inducible protein a
HUI97_02895	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
HUI97_02905	COG4251	negative regulation of phosphorylation
HUI97_02905	COG3706	GGDEF domain
HUI97_02905	COG2203	Gaf domain
HUI97_02905	COG5001	Diguanylate cyclase
HUI97_02910	COG4776	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction
HUI97_02925	COG2771	luxR family
HUI97_02935	COG0840	transmembrane signaling receptor activity
HUI97_02940	COG0632	four-way junction helicase activity
HUI97_02945	COG2255	four-way junction helicase activity
HUI97_02955	COG1294	oxidase, subunit
HUI97_02960	COG4890	Cyd operon protein YbgT
HUI97_02965	COG3790	cyd operon protein YbgE
HUI97_02970	COG0824	Thioesterase
HUI97_02975	COG0811	peptide transport
HUI97_02990	COG0823	Involved in the tonB-independent uptake of proteins
HUI97_02995	COG2885	chlorophyll binding
HUI97_03000	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
HUI97_03065	COG0733	neurotransmitter:sodium symporter activity
HUI97_03075	COG0733	neurotransmitter:sodium symporter activity
HUI97_03090	COG0561	phosphatase activity
HUI97_03140	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
HUI97_03145	COG1640	4-alpha-glucanotransferase
HUI97_03150	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
HUI97_03155	COG0676	glucose-6-phosphate 1-epimerase activity
HUI97_03160	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
HUI97_03165	COG0840	transmembrane signaling receptor activity
HUI97_03170	COG1585	Membrane protein implicated in regulation of membrane protease activity
HUI97_03175	COG0330	HflC and HflK could
HUI97_03180	COG1648	precorrin-2 dehydrogenase activity
HUI97_03180	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
HUI97_03185	COG0175	sulfate reduction
HUI97_03190	COG2895	sulfate adenylyltransferase (ATP) activity
HUI97_03195	COG0471	metal ion transport
HUI97_03195	COG3273	potassium ion transport
HUI97_03200	COG0529	Catalyzes the synthesis of activated sulfate
HUI97_03210	COG0840	transmembrane signaling receptor activity
HUI97_03230	COG1136	(ABC) transporter
HUI97_03245	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
HUI97_03260	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
HUI97_03265	COG0784	Response regulator, receiver
HUI97_03265	COG3437	response regulator, receiver
HUI97_03275	COG2076	Multidrug Resistance protein
HUI97_03280	COG2076	Multidrug Resistance protein
HUI97_03285	COG0346	lactoylglutathione lyase activity
HUI97_03290	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
HUI97_03295	COG1643	Atp-dependent helicase
HUI97_03305	COG1489	DNA binding
HUI97_03310	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
HUI97_03315	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
HUI97_03325	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
HUI97_03330	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
HUI97_03335	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
HUI97_03345	COG1823	symporter activity
HUI97_03365	COG1924	4 iron, 4 sulfur cluster binding
HUI97_03370	COG1775	2-hydroxyglutaryl-CoA dehydratase, D-component
HUI97_03375	COG0842	Transport permease protein
HUI97_03380	COG1131	(ABC) transporter
HUI97_03395	COG0163	prenyltransferase activity
HUI97_03400	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
HUI97_03405	COG0671	phosphoesterase, PA-phosphatase related
HUI97_03410	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
HUI97_03415	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
HUI97_03420	COG1151	hydroxylamine reductase activity
HUI97_03425	COG0783	Belongs to the Dps family
HUI97_03430	COG3023	N-Acetylmuramoyl-L-alanine amidase
HUI97_03435	COG4807	Protein conserved in bacteria
HUI97_03445	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HUI97_03450	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HUI97_03455	COG3956	TIGRFAM MazG family protein
HUI97_03460	COG0504	CTP synthase activity
HUI97_03465	COG0148	phosphopyruvate hydratase activity
HUI97_03530	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
HUI97_03540	COG0488	(ABC) transporter
HUI97_03560	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HUI97_03575	COG1794	racemase activity, acting on amino acids and derivatives
HUI97_03585	COG2731	YhcH YjgK YiaL family protein
HUI97_03590	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HUI97_03595	COG0668	transmembrane transport
HUI97_03600	COG1376	ErfK ybiS ycfS ynhG family protein
HUI97_03610	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HUI97_03615	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
HUI97_03620	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
HUI97_03625	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
HUI97_03630	COG0585	pseudouridine synthase activity
HUI97_03635	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
HUI97_03640	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
HUI97_03645	COG1238	metal cluster binding
HUI97_03650	COG1388	LysM domain
HUI97_03650	COG4942	peptidase
HUI97_03660	COG1902	pentaerythritol trinitrate reductase activity
HUI97_03670	COG2852	Protein conserved in bacteria
HUI97_03680	COG2957	Belongs to the agmatine deiminase family
HUI97_03685	COG0154	amidase activity
HUI97_03705	COG0513	Belongs to the DEAD box helicase family
HUI97_03710	COG2199	diguanylate cyclase activity
HUI97_03710	COG2203	Gaf domain
HUI97_03720	COG1912	Pfam S-adenosyl-l-methionine hydroxide adenosyltransferase
HUI97_03725	COG1858	cytochrome C peroxidase
HUI97_03775	COG2816	NAD+ diphosphatase activity
HUI97_03810	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
HUI97_03820	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
HUI97_03825	COG4991	sh3 domain protein
HUI97_03835	COG2816	NAD+ diphosphatase activity
HUI97_03840	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
HUI97_03845	COG1940	carbohydrate kinase activity
HUI97_03850	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
HUI97_03855	COG0126	phosphoglycerate kinase activity
HUI97_03860	COG0191	fructose-bisphosphate aldolase activity
HUI97_03865	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
HUI97_03885	COG4232	protein-disulfide reductase activity
HUI97_03910	COG0354	folic acid binding
HUI97_03915	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
HUI97_03925	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
HUI97_03930	COG1595	DNA-templated transcription, initiation
HUI97_03935	COG3073	An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E
HUI97_03940	COG3026	antisigma factor binding
HUI97_03950	COG0481	GTPase activity
HUI97_03955	COG0681	Belongs to the peptidase S26 family
HUI97_03970	COG1381	Involved in DNA repair and RecF pathway recombination
HUI97_03975	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
HUI97_03985	COG2350	Protein conserved in bacteria
HUI97_03990	COG2917	probably involved in intracellular septation
HUI97_03995	COG0076	glutamate decarboxylase activity
HUI97_04000	COG1272	protein, Hemolysin III
HUI97_04005	COG0569	domain protein
HUI97_04005	COG2985	domain, Protein
HUI97_04030	COG3076	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome
HUI97_04040	COG2203	Gaf domain
HUI97_04040	COG3706	GGDEF domain
HUI97_04040	COG4251	negative regulation of phosphorylation
HUI97_04040	COG5001	Diguanylate cyclase
HUI97_04050	COG3039	Transposase
HUI97_04055	COG0582	viral genome integration into host DNA
HUI97_04080	COG1858	cytochrome C peroxidase
HUI97_04090	COG2313	pseudouridylate synthase activity
HUI97_04095	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HUI97_04135	COG1765	OsmC-like protein
HUI97_04150	COG3954	Phosphoribulokinase
HUI97_04155	COG3089	Belongs to the UPF0270 family
HUI97_04160	COG3706	GGDEF domain
HUI97_04160	COG4251	negative regulation of phosphorylation
HUI97_04160	COG5001	Diguanylate cyclase
HUI97_04160	COG2203	Gaf domain
HUI97_04165	COG0429	hydrolase of the alpha beta-hydrolase fold
HUI97_04170	COG0835	chemotaxis
HUI97_04170	COG0784	Response regulator, receiver
HUI97_04180	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
HUI97_04185	COG1047	Peptidyl-prolyl cis-trans
HUI97_04200	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HUI97_04210	COG3340	Belongs to the peptidase S51 family
HUI97_04225	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HUI97_04235	COG3721	Heme iron utilization protein
HUI97_04240	COG0748	coenzyme F420 binding
HUI97_04260	COG4206	TonB-dependent receptor
HUI97_04265	COG2814	Major facilitator Superfamily
HUI97_04275	COG3655	Transcriptional regulator
HUI97_04285	COG0784	Response regulator, receiver
HUI97_04285	COG2205	protein histidine kinase activity
HUI97_04285	COG5002	protein histidine kinase activity
HUI97_04295	COG3706	GGDEF domain
HUI97_04310	COG3397	chitin binding
HUI97_04350	COG0835	chemotaxis
HUI97_04350	COG0784	Response regulator, receiver
HUI97_04355	COG2755	lipolytic protein G-D-S-L family
HUI97_04360	COG4181	ATPase activity
HUI97_04365	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
HUI97_04370	COG1090	epimerase
HUI97_04375	COG2200	EAL domain
HUI97_04380	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HUI97_04385	COG0220	tRNA (guanine-N7-)-methyltransferase activity
HUI97_04390	COG3171	Protein conserved in bacteria
HUI97_04395	COG2066	Belongs to the glutaminase family
HUI97_04400	COG2897	thiosulfate sulfurtransferase activity
HUI97_04415	COG0521	Mo-molybdopterin cofactor biosynthetic process
HUI97_04425	COG2966	Psort location CytoplasmicMembrane, score
HUI97_04430	COG3610	response to peptide
HUI97_04445	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
HUI97_04450	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
HUI97_04455	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
HUI97_04470	COG0786	glutamate:sodium symporter activity
HUI97_04475	COG0252	asparaginase activity
HUI97_04480	COG3139	Protein of unknown function (DUF1315)
HUI97_04500	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
HUI97_04505	COG0321	lipoyl(octanoyl) transferase activity
HUI97_04510	COG2921	Belongs to the UPF0250 family
HUI97_04515	COG1686	Belongs to the peptidase S11 family
HUI97_04520	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
HUI97_04525	COG2951	lytic endotransglycosylase activity
HUI97_04530	COG0772	Belongs to the SEDS family
HUI97_04535	COG0768	penicillin binding
HUI97_04540	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
HUI97_04545	COG0799	negative regulation of ribosome biogenesis
HUI97_04550	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
HUI97_04565	COG0495	leucyl-tRNA aminoacylation
HUI97_04570	COG2888	peptidyl-tyrosine sulfation
HUI97_04575	COG0312	modulator of DNA gyrase
HUI97_04585	COG0716	FMN binding
HUI97_04590	COG4974	Belongs to the 'phage' integrase family
HUI97_04595	COG1970	mechanosensitive ion channel activity
HUI97_04610	COG0789	Transcriptional regulator
HUI97_04615	COG0815	Transfers the fatty acyl group on membrane lipoproteins
HUI97_04620	COG4535	Mg2 and Co2 transporter CorC
HUI97_04625	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
HUI97_04630	COG1702	phosphate starvation-inducible protein PhoH
HUI97_04635	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
HUI97_04640	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
HUI97_04645	COG1335	isochorismatase
HUI97_04655	COG0583	DNA-binding transcription factor activity
HUI97_04665	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
HUI97_04680	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HUI97_04690	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
HUI97_04700	COG0516	GMP reductase activity
HUI97_04710	COG0642	Histidine kinase
HUI97_04725	COG4221	oxidoreductase activity
HUI97_04735	COG1022	Amp-dependent synthetase and ligase
HUI97_04750	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
HUI97_04765	COG3214	Protein conserved in bacteria
HUI97_04775	COG2195	Cleaves the N-terminal amino acid of tripeptides
HUI97_04780	COG0700	Nucleoside recognition
HUI97_04785	COG3366	ferrous iron transmembrane transporter activity
HUI97_04790	COG3080	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
HUI97_04795	COG3029	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
HUI97_04800	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
HUI97_04805	COG1053	succinate dehydrogenase
HUI97_04815	COG0584	glycerophosphoryl diester phosphodiesterase
HUI97_04820	COG1511	domain protein
HUI97_04820	COG3264	Mechanosensitive ion channel
HUI97_04830	COG0739	heme binding
HUI97_04840	COG0583	DNA-binding transcription factor activity
HUI97_04860	COG0583	DNA-binding transcription factor activity
HUI97_04865	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
HUI97_04895	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
HUI97_04900	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
HUI97_04910	COG0338	D12 class N6 adenine-specific DNA methyltransferase
HUI97_04915	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
HUI97_04925	COG0180	Tryptophanyl-tRNA synthetase
HUI97_04935	COG0512	Glutamine amidotransferase of anthranilate synthase
HUI97_04940	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
HUI97_04950	COG1012	belongs to the aldehyde dehydrogenase family
HUI97_04965	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
HUI97_04975	COG1013	pyruvate-flavodoxin oxidoreductase activity
HUI97_04975	COG0674	pyruvate-flavodoxin oxidoreductase activity
HUI97_04975	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
HUI97_04975	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
HUI97_04980	COG0366	Alpha amylase catalytic
HUI97_05000	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
HUI97_05010	COG0471	metal ion transport
HUI97_05010	COG0490	domain, Protein
HUI97_05055	COG0012	GTP binding
HUI97_05060	COG0193	aminoacyl-tRNA hydrolase activity
HUI97_05065	COG0737	Belongs to the 5'-nucleotidase family
HUI97_05070	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HUI97_05080	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
HUI97_05085	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
HUI97_05090	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
HUI97_05095	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
HUI97_05100	COG2890	protein-(glutamine-N5) methyltransferase activity
HUI97_05110	COG2912	Transglutaminase-like superfamily
HUI97_05115	COG2877	3-deoxy-8-phosphooctulonate synthase activity
HUI97_05135	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
HUI97_05145	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
HUI97_05145	COG3408	Glycogen debranching enzyme
HUI97_05155	COG1881	PFAM PEBP family protein
HUI97_05160	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
HUI97_05175	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
HUI97_05185	COG0583	DNA-binding transcription factor activity
HUI97_05190	COG1028	Short-chain dehydrogenase reductase Sdr
HUI97_05200	COG0616	signal peptide processing
HUI97_05205	COG2211	Major facilitator Superfamily
HUI97_05210	COG3706	GGDEF domain
HUI97_05215	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
HUI97_05225	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
HUI97_05230	COG0826	peptidase U32
HUI97_05235	COG2199	diguanylate cyclase activity
HUI97_05235	COG2203	Gaf domain
HUI97_05235	COG2200	EAL domain
HUI97_05260	COG2197	response regulator
HUI97_05290	COG3724	N-succinylarginine dihydrolase activity
HUI97_05310	COG0840	transmembrane signaling receptor activity
HUI97_05320	COG2971	BadF BadG BcrA BcrD
HUI97_05330	COG4608	Belongs to the ABC transporter superfamily
HUI97_05335	COG0444	Belongs to the ABC transporter superfamily
HUI97_05340	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
HUI97_05385	COG3220	belongs to the UPF0276 family
HUI97_05415	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
HUI97_05420	COG1289	transmembrane transporter activity
HUI97_05425	COG0303	'Molybdopterin
HUI97_05430	COG0746	molybdenum cofactor guanylyltransferase activity
HUI97_05440	COG4662	Binding-protein-dependent transport system inner membrane component
HUI97_05450	COG2204	response regulator
HUI97_05455	COG3852	Histidine kinase
HUI97_05465	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
HUI97_05500	COG3383	formate dehydrogenase (NAD+) activity
HUI97_05500	COG3383	formate dehydrogenase (NAD+) activity
HUI97_05505	COG0437	4 iron, 4 sulfur cluster binding
HUI97_05525	COG0281	malic enzyme
HUI97_05545	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HUI97_05575	COG0837	glucose binding
HUI97_05580	COG1737	Transcriptional regulator
HUI97_05585	COG0469	pyruvate kinase activity
HUI97_05600	COG1677	Flagellar hook-basal body complex protein FliE
HUI97_05610	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
HUI97_05665	COG1684	flagellar biosynthetic protein fliR
HUI97_05675	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
HUI97_05700	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
HUI97_05705	COG0784	Response regulator, receiver
HUI97_05705	COG0643	Histidine kinase
HUI97_05705	COG2198	Histidine kinase
HUI97_05710	COG2201	protein-glutamate methylesterase activity
HUI97_05715	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
HUI97_05720	COG1360	Flagellar Motor Protein
HUI97_05725	COG1192	Involved in chromosome partitioning
HUI97_05735	COG0835	chemotaxis
HUI97_05750	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
HUI97_05755	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
HUI97_05760	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
HUI97_05765	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
HUI97_05770	COG1138	Cytochrome C-type biogenesis protein
HUI97_05775	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
HUI97_05780	COG3088	subunit of a heme lyase
HUI97_05780	COG4235	cytochrome complex assembly
HUI97_05790	COG2853	Lipoprotein
HUI97_05805	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
HUI97_05810	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
HUI97_05810	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
HUI97_05840	COG0259	pyridoxamine-phosphate oxidase activity
HUI97_05845	COG0625	glutathione transferase activity
HUI97_05865	COG2850	peptidyl-arginine hydroxylation
HUI97_05870	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
HUI97_05875	COG2915	High frequency lysogenization protein hflD homolog
HUI97_05880	COG0482	sulfurtransferase activity
HUI97_05885	COG1051	belongs to the nudix hydrolase family
HUI97_05890	COG1187	pseudouridine synthase activity
HUI97_05900	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HUI97_05905	COG2271	Major facilitator Superfamily
HUI97_05910	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HUI97_05910	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HUI97_05910	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
HUI97_05935	COG0789	Transcriptional regulator
HUI97_05945	COG1609	Transcriptional regulator
HUI97_05950	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HUI97_05950	COG1263	PTS System
HUI97_05955	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
HUI97_05965	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
HUI97_05975	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HUI97_05980	COG1960	acyl-CoA dehydrogenase activity
HUI97_05990	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
HUI97_06000	COG1940	carbohydrate kinase activity
HUI97_06005	COG0457	Tetratricopeptide repeat
HUI97_06010	COG0477	Major facilitator Superfamily
HUI97_06010	COG2814	Major facilitator Superfamily
HUI97_06020	COG3383	formate dehydrogenase (NAD+) activity
HUI97_06030	COG0784	Response regulator, receiver
HUI97_06030	COG2205	protein histidine kinase activity
HUI97_06040	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
HUI97_06045	COG2867	negative regulation of translational initiation
HUI97_06050	COG2914	Belongs to the UPF0125 (RnfH) family
HUI97_06055	COG1473	amidohydrolase
HUI97_06060	COG1960	acyl-CoA dehydrogenase activity
HUI97_06065	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
HUI97_06070	COG0121	glutamine amidotransferase
HUI97_06100	COG2197	response regulator
HUI97_06105	COG3850	Histidine kinase
HUI97_06110	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
HUI97_06115	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
HUI97_06125	COG0243	molybdopterin cofactor binding
HUI97_06130	COG0437	4 iron, 4 sulfur cluster binding
HUI97_06135	COG0348	domain, Protein
HUI97_06145	COG3005	denitrification pathway
HUI97_06150	COG0521	Mo-molybdopterin cofactor biosynthetic process
HUI97_06155	COG0315	cyclic pyranopterin monophosphate synthase activity
HUI97_06160	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
HUI97_06180	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
HUI97_06185	COG2267	carboxylic ester hydrolase activity
HUI97_06190	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
HUI97_06200	COG0302	gtp cyclohydrolase
HUI97_06205	COG0840	transmembrane signaling receptor activity
HUI97_06210	COG2759	Belongs to the formate--tetrahydrofolate ligase family
HUI97_06220	COG0583	DNA-binding transcription factor activity
HUI97_06225	COG2353	YceI-like domain
HUI97_06235	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
HUI97_06250	COG2195	Cleaves the N-terminal amino acid of tripeptides
HUI97_06255	COG1166	arginine decarboxylase activity
HUI97_06275	COG0814	amino acid
HUI97_06285	COG3681	Belongs to the UPF0597 family
HUI97_06290	COG2964	Protein conserved in bacteria
HUI97_06300	COG2932	Transcriptional regulator
HUI97_06415	COG4373	Mu-like prophage FluMu protein gp28
HUI97_06420	COG4383	Mu-like prophage protein gp29
HUI97_06440	COG4388	Caudovirus prohead serine protease
HUI97_06445	COG4397	Mu-like prophage major head subunit gpT
HUI97_06470	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
HUI97_06535	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
HUI97_06540	COG1288	antiporter activity
HUI97_06545	COG0436	Aminotransferase
HUI97_06555	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
HUI97_06560	COG0739	heme binding
HUI97_06560	COG0741	lytic transglycosylase activity
HUI97_06560	COG1196	nuclear chromosome segregation
HUI97_06575	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HUI97_06585	COG0788	formyltetrahydrofolate deformylase activity
HUI97_06590	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
HUI97_06610	COG0791	NLP P60 protein
HUI97_06615	COG3129	Specifically methylates the adenine in position 1618 of 23S rRNA
HUI97_06625	COG0471	metal ion transport
HUI97_06635	COG1376	ErfK ybiS ycfS ynhG family protein
HUI97_06635	COG1388	LysM domain
HUI97_06645	COG0582	viral genome integration into host DNA
HUI97_06655	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
HUI97_06660	COG0732	type I restriction modification DNA specificity domain
HUI97_06665	COG1401	restriction endodeoxyribonuclease activity
HUI97_06665	COG1401	restriction endodeoxyribonuclease activity
HUI97_06675	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
HUI97_06695	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HUI97_06720	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HUI97_06725	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HUI97_06730	COG0745	RESPONSE REGULATOR receiver
HUI97_06735	COG5000	phosphorelay sensor kinase activity
HUI97_06735	COG5002	protein histidine kinase activity
HUI97_06760	COG0741	lytic transglycosylase activity
HUI97_06760	COG1388	LysM domain
HUI97_06765	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
HUI97_06770	COG2226	methyltransferase
HUI97_06775	COG0328	RNA-DNA hybrid ribonuclease activity
HUI97_06780	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
HUI97_06790	COG0784	Response regulator, receiver
HUI97_06790	COG3437	response regulator, receiver
HUI97_06795	COG2375	cellular response to nickel ion
HUI97_06800	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HUI97_06805	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HUI97_06810	COG1120	ATPase activity
HUI97_06815	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
HUI97_06825	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HUI97_06830	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HUI97_06865	COG0708	Exodeoxyribonuclease III
HUI97_06895	COG3132	Protein of unknown function, DUF480
HUI97_06900	COG5001	Diguanylate cyclase
HUI97_06900	COG3300	MHYT domain
HUI97_06910	COG2841	Protein conserved in bacteria
HUI97_06920	COG0534	Mate efflux family protein
HUI97_06955	COG1309	transcriptional regulator
HUI97_06990	COG3152	Membrane
HUI97_07005	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HUI97_07015	COG2207	Transcriptional regulator
HUI97_07020	COG0538	isocitrate dehydrogenase activity
HUI97_07030	COG3048	D-serine ammonia-lyase activity
HUI97_07035	COG2610	gluconate transmembrane transporter activity
HUI97_07040	COG0583	DNA-binding transcription factor activity
HUI97_07050	COG0791	NLP P60 protein
HUI97_07055	COG0583	DNA-binding transcription factor activity
HUI97_07060	COG0450	alkyl hydroperoxide reductase
HUI97_07080	COG0500	methyltransferase
HUI97_07085	COG4106	trans-aconitate 2-methyltransferase activity
HUI97_07090	COG1801	Protein of unknown function DUF72
HUI97_07100	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
HUI97_07105	COG0217	transcriptional regulatory protein
HUI97_07115	COG1012	belongs to the aldehyde dehydrogenase family
HUI97_07115	COG1454	alcohol dehydrogenase
HUI97_07120	COG2095	MarC family integral membrane protein
HUI97_07130	COG0601	transmembrane transport
HUI97_07135	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
HUI97_07150	COG0861	Integral membrane protein TerC family
HUI97_07155	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HUI97_07185	COG4138	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system
HUI97_07190	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
HUI97_07195	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
HUI97_07200	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
HUI97_07205	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
HUI97_07210	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
HUI97_07225	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
HUI97_07235	COG0505	Belongs to the CarA family
HUI97_07240	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
HUI97_07275	COG0346	lactoylglutathione lyase activity
HUI97_07280	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
HUI97_07285	COG4660	Part of a membrane complex involved in electron transport
HUI97_07290	COG4659	FMN binding
HUI97_07295	COG4658	electron transport chain
HUI97_07305	COG2878	Part of a membrane complex involved in electron transport
HUI97_07310	COG4657	Part of a membrane complex involved in electron transport
HUI97_07315	COG1061	Type III restriction enzyme res subunit
HUI97_07325	COG0346	lactoylglutathione lyase activity
HUI97_07335	COG1187	pseudouridine synthase activity
HUI97_07340	COG2807	transmembrane transport
HUI97_07345	COG0583	DNA-binding transcription factor activity
HUI97_07360	COG2979	Protein of unknown function (DUF533)
HUI97_07370	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HUI97_07380	COG1294	oxidase, subunit
HUI97_07400	COG3220	belongs to the UPF0276 family
HUI97_07415	COG2249	NAD(P)H dehydrogenase (quinone) activity
HUI97_07420	COG2814	Major facilitator Superfamily
HUI97_07425	COG0656	L-ascorbic acid biosynthetic process
HUI97_07450	COG0583	DNA-binding transcription factor activity
HUI97_07460	COG0840	transmembrane signaling receptor activity
HUI97_07465	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
HUI97_07470	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
HUI97_07475	COG2271	Major facilitator Superfamily
HUI97_07480	COG1349	DNA-binding transcription factor activity
HUI97_07490	COG0584	glycerophosphoryl diester phosphodiesterase
HUI97_07495	COG4574	serine-type endopeptidase inhibitor activity
HUI97_07500	COG3085	chromosome segregation
HUI97_07505	COG0583	DNA-binding transcription factor activity
HUI97_07515	COG1448	Aminotransferase
HUI97_07530	COG2333	competence protein COMEC
HUI97_07530	COG0658	competence protein
HUI97_07540	COG1663	tetraacyldisaccharide 4'-kinase activity
HUI97_07545	COG2835	tetraacyldisaccharide 4'-kinase activity
HUI97_07550	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
HUI97_07555	COG2197	response regulator
HUI97_07560	COG0322	excinuclease ABC activity
HUI97_07640	COG4695	Portal protein
HUI97_07650	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
HUI97_07655	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HUI97_07750	COG4974	Belongs to the 'phage' integrase family
HUI97_07780	COG0642	Histidine kinase
HUI97_07785	COG2261	transglycosylase associated protein
HUI97_07800	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
HUI97_07810	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
HUI97_07815	COG0215	cysteine-tRNA ligase activity
HUI97_07860	COG2119	membrane
HUI97_07865	COG0023	Translation Initiation Factor
HUI97_07890	COG0513	Belongs to the DEAD box helicase family
HUI97_07895	COG0493	'glutamate synthase
HUI97_07900	COG0067	glutamate synthase
HUI97_07900	COG0069	glutamate synthase activity
HUI97_07900	COG0070	glutamate synthase
HUI97_07905	COG1242	4 iron, 4 sulfur cluster binding
HUI97_07950	COG3634	alkyl hydroperoxide reductase activity
HUI97_07960	COG0517	IMP dehydrogenase activity
HUI97_07965	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
HUI97_07970	COG0343	queuine tRNA-ribosyltransferase activity
HUI97_07975	COG1862	Preprotein translocase
HUI97_07980	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
HUI97_07985	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
HUI97_08000	COG0826	peptidase U32
HUI97_08005	COG0826	peptidase U32
HUI97_08010	COG3154	lipid carrier protein
HUI97_08030	COG1104	cysteine desulfurase activity
HUI97_08035	COG0822	iron-sulfur transferase activity
HUI97_08045	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
HUI97_08050	COG0443	Heat shock 70 kDa protein
HUI97_08055	COG0633	Ferredoxin
HUI97_08070	COG0105	UTP biosynthetic process
HUI97_08075	COG0820	rRNA (adenine-C2-)-methyltransferase activity
HUI97_08090	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
HUI97_08095	COG0124	histidyl-tRNA synthetase
HUI97_08100	COG2976	Protein conserved in bacteria
HUI97_08105	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
HUI97_08110	COG1160	GTP binding
HUI97_08115	COG1645	bacterial-type flagellum-dependent swarming motility
HUI97_08120	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
HUI97_08125	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HUI97_08125	COG0047	phosphoribosylformylglycinamidine synthase activity
HUI97_08130	COG1007	ATP synthesis coupled electron transport
HUI97_08135	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
HUI97_08145	COG0713	ATP synthesis coupled electron transport
HUI97_08150	COG0839	Belongs to the complex I subunit 6 family
HUI97_08155	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
HUI97_08160	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
HUI97_08165	COG1034	ATP synthesis coupled electron transport
HUI97_08180	COG0649	NAD binding
HUI97_08180	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
HUI97_08185	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
HUI97_08190	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
HUI97_08210	COG1770	oligopeptidase
HUI97_08215	COG4771	TonB-dependent receptor
HUI97_08220	COG1360	Flagellar Motor Protein
HUI97_08225	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
HUI97_08240	COG5642	Protein of unknown function (DUF2384)
HUI97_08260	COG0443	Heat shock 70 kDa protein
HUI97_08265	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
HUI97_08295	COG4974	Belongs to the 'phage' integrase family
HUI97_08315	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
HUI97_08325	COG3770	Murein endopeptidase that cleaves the D-alanyl-meso-2,6- diamino-pimelyl amide bond that connects peptidoglycan strands. Likely plays a role in the removal of murein from the sacculus
HUI97_08330	COG0765	amino acid transport
HUI97_08335	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HUI97_08340	COG0765	amino acid transport
HUI97_08345	COG1126	abc transporter atp-binding protein
HUI97_08355	COG0724	RNA recognition motif
HUI97_08360	COG4989	oxidoreductase activity
HUI97_08385	COG3437	response regulator, receiver
HUI97_08390	COG0583	DNA-binding transcription factor activity
HUI97_08395	COG3300	MHYT domain
HUI97_08395	COG5001	Diguanylate cyclase
HUI97_08400	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
HUI97_08425	COG0527	aspartate kinase activity
HUI97_08430	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
HUI97_08430	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
HUI97_08435	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HUI97_08455	COG0596	Alpha beta hydrolase
HUI97_08475	COG0577	efflux transmembrane transporter activity
HUI97_08480	COG1136	(ABC) transporter
HUI97_08495	COG2814	Major facilitator Superfamily
HUI97_08515	COG0672	)-iron permease
HUI97_08550	COG0659	secondary active sulfate transmembrane transporter activity
HUI97_08595	COG3039	Transposase
HUI97_08620	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
HUI97_08625	COG0326	Molecular chaperone. Has ATPase activity
HUI97_08630	COG4172	Belongs to the ABC transporter superfamily
HUI97_08635	COG4172	Belongs to the ABC transporter superfamily
HUI97_08640	COG4171	peptide transport system, permease
HUI97_08645	COG4168	peptide transport system, permease
HUI97_08650	COG0747	negative chemotaxis
HUI97_08655	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
HUI97_08660	COG1842	Phage shock protein A
HUI97_08675	COG3106	COG3106 Predicted ATPase
HUI97_08680	COG3768	UPF0283 membrane protein
HUI97_08685	COG0583	DNA-binding transcription factor activity
HUI97_08690	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
HUI97_08695	COG3842	ATPase activity
HUI97_08700	COG1176	ABC-type spermidine putrescine transport system, permease component I
HUI97_08705	COG1177	transmembrane transport
HUI97_08710	COG1012	belongs to the aldehyde dehydrogenase family
HUI97_08720	COG2154	pterin-4-alpha-carbinolamine dehydratase
HUI97_08735	COG2199	diguanylate cyclase activity
HUI97_08740	COG2885	chlorophyll binding
HUI97_08745	COG0861	Integral membrane protein TerC family
HUI97_08775	COG2910	NAD(P)H-binding
HUI97_08780	COG0583	DNA-binding transcription factor activity
HUI97_08785	COG0583	DNA-binding transcription factor activity
HUI97_08790	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
HUI97_08800	COG0583	DNA-binding transcription factor activity
HUI97_08805	COG2723	6-phospho-beta-galactosidase activity
HUI97_08810	COG1944	ATP diphosphatase activity
HUI97_08815	COG2116	formate transmembrane transporter activity
HUI97_08820	COG1882	Formate acetyltransferase
HUI97_08825	COG2983	Belongs to the UPF0260 family
HUI97_08830	COG4166	transmembrane transport
HUI97_08835	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
HUI97_08840	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
HUI97_08850	COG4591	ABC-type transport system involved in lipoprotein release permease component
HUI97_08855	COG1136	(ABC) transporter
HUI97_08860	COG4591	ABC-type transport system involved in lipoprotein release permease component
HUI97_08865	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
HUI97_08875	COG0544	peptidyl-prolyl cis-trans isomerase activity
HUI97_08880	COG0740	serine-type endopeptidase activity
HUI97_08885	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
HUI97_08890	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
HUI97_08895	COG0776	regulation of translation
HUI97_08900	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
HUI97_08905	COG0488	(ABC) transporter
HUI97_08910	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HUI97_08915	COG3162	membrane
HUI97_08930	COG1024	Enoyl-CoA hydratase
HUI97_08935	COG1115	amino acid carrier protein
HUI97_08950	COG1584	GPR1 FUN34 yaaH family protein
HUI97_08980	COG1024	Enoyl-CoA hydratase
HUI97_08985	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
HUI97_08990	COG1960	acyl-CoA dehydrogenase activity
HUI97_08995	COG1960	acyl-CoA dehydrogenase activity
HUI97_09000	COG1024	Enoyl-CoA hydratase
HUI97_09005	COG1024	Enoyl-CoA hydratase
HUI97_09015	COG1028	Short-chain dehydrogenase reductase Sdr
HUI97_09025	COG0730	response to heat
HUI97_09090	COG2003	Belongs to the UPF0758 family
HUI97_09105	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
HUI97_09165	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
HUI97_09170	COG1215	transferase activity, transferring glycosyl groups
HUI97_09175	COG0438	transferase activity, transferring glycosyl groups
HUI97_09190	COG1787	Restriction endonuclease
HUI97_09190	COG1715	Restriction endonuclease
HUI97_09220	COG0438	transferase activity, transferring glycosyl groups
HUI97_09240	COG0438	transferase activity, transferring glycosyl groups
HUI97_09245	COG0438	transferase activity, transferring glycosyl groups
HUI97_09250	COG2203	Gaf domain
HUI97_09250	COG3706	GGDEF domain
HUI97_09250	COG4251	negative regulation of phosphorylation
HUI97_09250	COG5001	Diguanylate cyclase
HUI97_09255	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
HUI97_09260	COG3437	response regulator, receiver
HUI97_09270	COG3850	Histidine kinase
HUI97_09270	COG4999	Histidine kinase
HUI97_09270	COG3437	response regulator, receiver
HUI97_09270	COG2205	protein histidine kinase activity
HUI97_09275	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
HUI97_09280	COG0437	4 iron, 4 sulfur cluster binding
HUI97_09285	COG5557	Pfam Polysulphide reductase, NrfD
HUI97_09290	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
HUI97_09295	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
HUI97_09300	COG1773	rubredoxin
HUI97_09315	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
HUI97_09325	COG3842	ATPase activity
HUI97_09330	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
HUI97_09335	COG0375	protein maturation
HUI97_09340	COG0309	Hydrogenase expression formation protein (HypE)
HUI97_09350	COG0298	carbon dioxide binding
HUI97_09355	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
HUI97_09365	COG1921	L-seryl-tRNASec selenium transferase activity
HUI97_09375	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
HUI97_09385	COG3260	NADH ubiquinone oxidoreductase 20
HUI97_09390	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
HUI97_09395	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
HUI97_09395	COG3261	NADH dehydrogenase
HUI97_09400	COG0650	Formate hydrogenlyase subunit 4
HUI97_09405	COG0651	ATP synthesis coupled electron transport
HUI97_09410	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
HUI97_09425	COG1560	Kdo2-lipid A biosynthetic process
HUI97_09430	COG1560	Kdo2-lipid A biosynthetic process
HUI97_09445	COG2199	diguanylate cyclase activity
HUI97_09445	COG2203	Gaf domain
HUI97_09455	COG0417	DNA replication proofreading
HUI97_09470	COG1451	nucleotide metabolic process
HUI97_09485	COG3069	C4-dicarboxylate transmembrane transporter activity
HUI97_09500	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
HUI97_09500	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
HUI97_09505	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
HUI97_09510	COG2985	domain, Protein
HUI97_09510	COG0569	domain protein
HUI97_09525	COG0556	nucleotide-excision repair
HUI97_09535	COG0586	Pfam SNARE associated Golgi protein
HUI97_09540	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
HUI97_09545	COG3067	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
HUI97_09560	COG4681	YaeQ
HUI97_09575	COG3829	transcription factor binding
HUI97_09605	COG0534	Mate efflux family protein
HUI97_09615	COG0307	riboflavin synthase, alpha
HUI97_09625	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
HUI97_09630	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
HUI97_09635	COG0697	spore germination
HUI97_09640	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
HUI97_09680	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
HUI97_09685	COG3099	Belongs to the UPF0263 family
HUI97_09690	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
HUI97_09695	COG2894	cell division
HUI97_09700	COG0850	regulation of cytokinetic process
HUI97_09705	COG3100	YcgL domain-containing protein
HUI97_09710	COG1760	l-serine dehydratase
HUI97_09715	COG1760	l-serine dehydratase
HUI97_09720	COG3123	guanosine phosphorylase activity
HUI97_09730	COG0205	6-phosphofructokinase activity
HUI97_09740	COG1434	Gram-negative-bacterium-type cell wall biogenesis
HUI97_09745	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
HUI97_09755	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
HUI97_09760	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
HUI97_09780	COG0242	peptide deformylase activity
HUI97_09805	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
HUI97_09810	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
HUI97_09815	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
HUI97_09825	COG0549	Belongs to the carbamate kinase family
HUI97_09830	COG0697	spore germination
HUI97_09840	COG3608	succinylglutamate desuccinylase aspartoacylase
HUI97_09840	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
HUI97_09845	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
HUI97_09850	COG2068	MobA-Related Protein
HUI97_09860	COG0493	'glutamate synthase
HUI97_09860	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
HUI97_09865	COG0402	S-adenosylhomocysteine deaminase activity
HUI97_09870	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
HUI97_09875	COG1529	Aldehyde oxidase and xanthine dehydrogenase
HUI97_09875	COG2080	2 iron, 2 sulfur cluster binding
HUI97_09880	COG2233	PERMEase
HUI97_09885	COG0402	S-adenosylhomocysteine deaminase activity
HUI97_09890	COG2252	PERMEase
HUI97_09895	COG1529	Aldehyde oxidase and xanthine dehydrogenase
HUI97_09900	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
HUI97_09905	COG2080	2 iron, 2 sulfur cluster binding
HUI97_09910	COG3134	Outer membrane lipoprotein
HUI97_09920	COG1288	antiporter activity
HUI97_09925	COG0318	PFAM AMP-dependent synthetase and ligase
HUI97_09930	COG2199	diguanylate cyclase activity
HUI97_09945	COG0107	imidazoleglycerol-phosphate synthase activity
HUI97_09950	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
HUI97_09955	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
HUI97_09960	COG0131	Imidazoleglycerol-phosphate dehydratase
HUI97_09960	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
HUI97_09965	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
HUI97_09970	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
HUI97_09975	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
HUI97_09985	COG1199	ATP-dependent helicase activity
HUI97_09990	COG1214	PFAM Peptidase M22, glycoprotease
HUI97_10000	COG2267	carboxylic ester hydrolase activity
HUI97_10005	COG0318	PFAM AMP-dependent synthetase and ligase
HUI97_10015	COG3385	transposase activity
HUI97_10020	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
HUI97_10025	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
HUI97_10030	COG0709	Synthesizes selenophosphate from selenide and ATP
HUI97_10045	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
HUI97_10050	COG0840	transmembrane signaling receptor activity
HUI97_10055	COG1254	Belongs to the acylphosphatase family
HUI97_10065	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HUI97_10065	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HUI97_10070	COG0489	protein tyrosine kinase activity
HUI97_10075	COG0572	uridine kinase
HUI97_10080	COG0717	Belongs to the dCTP deaminase family
HUI97_10085	COG0306	phosphate transporter
HUI97_10095	COG1530	ribonuclease E activity
HUI97_10100	COG0564	pseudouridine synthase activity
HUI97_10105	COG0546	phosphoglycolate phosphatase activity
HUI97_10110	COG0424	maF-like protein
HUI97_10115	COG1399	metal-binding, possibly nucleic acid-binding protein
HUI97_10120	COG0333	Belongs to the bacterial ribosomal protein bL32 family
HUI97_10125	COG0416	fatty acid biosynthetic process
HUI97_10130	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HUI97_10140	COG1028	Short-chain dehydrogenase reductase Sdr
HUI97_10145	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
HUI97_10150	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
HUI97_10155	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
HUI97_10160	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
HUI97_10165	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
HUI97_10170	COG0470	DNA polymerase III
HUI97_10175	COG0084	hydrolase, TatD family'
HUI97_10225	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
HUI97_10245	COG0583	DNA-binding transcription factor activity
HUI97_10300	COG1357	PFAM Pentapeptide repeats (8 copies)
HUI97_10355	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
HUI97_10355	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
HUI97_10360	COG3008	intermembrane lipid transfer
HUI97_10365	COG2995	paraquat-inducible protein a
HUI97_10375	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
HUI97_10380	COG0372	Belongs to the citrate synthase family
HUI97_10425	COG4221	oxidoreductase activity
HUI97_10435	COG3141	response to X-ray
HUI97_10455	COG1067	ATP-dependent peptidase activity
HUI97_10460	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
HUI97_10470	COG0488	(ABC) transporter
HUI97_10480	COG0116	Belongs to the methyltransferase superfamily
HUI97_10480	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
HUI97_10485	COG0257	Belongs to the bacterial ribosomal protein bL36 family
HUI97_10490	COG0254	rRNA binding
HUI97_10500	COG0167	dihydroorotate dehydrogenase activity
HUI97_10505	COG2902	Dehydrogenase
HUI97_10515	COG0308	aminopeptidase N
HUI97_10525	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
HUI97_10530	COG1956	GAF domain-containing protein
HUI97_10540	COG3278	Belongs to the heme-copper respiratory oxidase family
HUI97_10555	COG2010	Cytochrome c
HUI97_10565	COG2217	Heavy metal translocating P-type atpase
HUI97_10580	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
HUI97_10585	COG0589	response to stress
HUI97_10590	COG0037	tRNA processing
HUI97_10615	COG1177	transmembrane transport
HUI97_10630	COG0625	glutathione transferase activity
HUI97_10635	COG1869	D-ribose catabolic process
HUI97_10640	COG1129	ABC transporter
HUI97_10645	COG1172	Belongs to the binding-protein-dependent transport system permease family
HUI97_10650	COG1879	ABC-type sugar transport system periplasmic component
HUI97_10655	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HUI97_10660	COG1609	Transcriptional regulator
HUI97_10665	COG5001	Diguanylate cyclase
HUI97_10665	COG3300	MHYT domain
HUI97_10690	COG2205	protein histidine kinase activity
HUI97_10690	COG0784	Response regulator, receiver
HUI97_10695	COG0776	regulation of translation
HUI97_10700	COG0072	phenylalanine-tRNA ligase activity
HUI97_10700	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HUI97_10705	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
HUI97_10710	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
HUI97_10715	COG0291	Belongs to the bacterial ribosomal protein bL35 family
HUI97_10720	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
HUI97_10725	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
HUI97_10745	COG0366	Alpha amylase catalytic
HUI97_10755	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
HUI97_10765	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HUI97_10770	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HUI97_10775	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
HUI97_10780	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
HUI97_10785	COG3313	Fe-S protein
HUI97_10790	COG2942	2-epimerase
HUI97_10795	COG3716	PTS system mannose fructose sorbose family IID component
HUI97_10800	COG3715	PTS system
HUI97_10805	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HUI97_10805	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
HUI97_10820	COG1609	Transcriptional regulator
HUI97_10825	COG2140	Oxalate decarboxylase
HUI97_10835	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HUI97_10835	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HUI97_10835	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
HUI97_10840	COG1105	Belongs to the carbohydrate kinase PfkB family
HUI97_10850	COG1609	Transcriptional regulator
HUI97_10855	COG0814	amino acid
HUI97_10865	COG3788	relative of glutathione S-transferase, MAPEG superfamily
HUI97_10875	COG0513	Belongs to the DEAD box helicase family
HUI97_10885	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
HUI97_10890	COG2890	protein-(glutamine-N5) methyltransferase activity
HUI97_10895	COG2840	Smr protein MutS2
HUI97_10900	COG3706	GGDEF domain
HUI97_10920	COG2824	Alkylphosphonate utilization operon protein PhnA
HUI97_10935	COG0494	nUDIX hydrolase
HUI97_10940	COG0814	amino acid
HUI97_10945	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
HUI97_10950	COG0514	ATP-dependent DNA helicase (RecQ)
HUI97_10955	COG2766	serine protein kinase
HUI97_10960	COG2718	Belongs to the UPF0229 family
HUI97_10965	COG2719	SpoVR family
HUI97_10975	COG1024	Enoyl-CoA hydratase
HUI97_10975	COG1250	3-hydroxyacyl-CoA dehydrogenase
HUI97_10980	COG0183	Belongs to the thiolase family
HUI97_10985	COG0714	Associated with various cellular activities
HUI97_11005	COG2304	oxidoreductase activity
HUI97_11015	COG1595	DNA-templated transcription, initiation
HUI97_11030	COG2067	long-chain fatty acid transport protein
HUI97_11035	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
HUI97_11050	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
HUI97_11060	COG1643	Atp-dependent helicase
HUI97_11065	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
HUI97_11065	COG0517	IMP dehydrogenase activity
HUI97_11065	COG0617	tRNA 3'-terminal CCA addition
HUI97_11070	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
HUI97_11080	COG2925	Exonuclease
HUI97_11090	COG3345	alpha-galactosidase
HUI97_11095	COG1380	Effector of murein hydrolase LrgA
HUI97_11100	COG1346	cytolysis
HUI97_11105	COG0295	cytidine deaminase activity
HUI97_11110	COG3033	Beta-eliminating lyase
HUI97_11120	COG3046	protein related to deoxyribodipyrimidine photolyase
HUI97_11125	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
HUI97_11130	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
HUI97_11155	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
HUI97_11170	COG3158	transport of potassium into the cell
HUI97_11180	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
HUI97_11185	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
HUI97_11195	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
HUI97_11200	COG2832	Protein of unknown function (DUF454)
HUI97_11205	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HUI97_11220	COG1011	Hydrolase
HUI97_11225	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
HUI97_11275	COG3593	DNA synthesis involved in DNA repair
HUI97_11290	COG0583	DNA-binding transcription factor activity
HUI97_11295	COG0730	response to heat
HUI97_11300	COG3148	PFAM DTW domain containing protein
HUI97_11305	COG1940	carbohydrate kinase activity
HUI97_11305	COG1846	Transcriptional regulator
HUI97_11310	COG0840	transmembrane signaling receptor activity
HUI97_11315	COG3012	SEC-C Motif Domain Protein
HUI97_11320	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
HUI97_11325	COG3075	Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses fumarate or nitrate as electron acceptor
HUI97_11335	COG0247	lactate metabolic process
HUI97_11355	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
HUI97_11360	COG0437	4 iron, 4 sulfur cluster binding
HUI97_11365	COG3301	Polysulphide reductase, NrfD
HUI97_11370	COG1138	Cytochrome C-type biogenesis protein
HUI97_11380	COG3088	subunit of a heme lyase
HUI97_11380	COG4235	cytochrome complex assembly
HUI97_11395	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
HUI97_11400	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
HUI97_11405	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
HUI97_11415	COG1840	ABC-type Fe3 transport system, periplasmic component
HUI97_11420	COG3842	ATPase activity
HUI97_11430	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
HUI97_11445	COG0045	succinate-CoA ligase (ADP-forming) activity
HUI97_11450	COG0508	dehydrogenase complex catalyzes the overall conversion of
HUI97_11455	COG0567	Dehydrogenase, E1 component
HUI97_11465	COG1053	succinate dehydrogenase
HUI97_11470	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
HUI97_11475	COG2009	succinate dehydrogenase
HUI97_11515	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
HUI97_11530	COG2501	S4 domain
HUI97_11540	COG1132	(ABC) transporter
HUI97_11545	COG1132	(ABC) transporter
HUI97_11555	COG3118	belongs to the thioredoxin family
HUI97_11560	COG0471	metal ion transport
HUI97_11570	COG0058	SHG alpha-glucan phosphorylase activity
HUI97_11585	COG0697	spore germination
HUI97_11595	COG2062	phosphohistidine phosphatase, SixA
HUI97_11600	COG1025	Belongs to the peptidase M16 family
HUI97_11640	COG0518	GMP synthase (glutamine-hydrolyzing) activity
HUI97_11640	COG0519	Catalyzes the synthesis of GMP from XMP
HUI97_11645	COG0517	IMP dehydrogenase activity
HUI97_11645	COG0516	GMP reductase activity
HUI97_11655	COG0366	Alpha amylase catalytic
HUI97_11655	COG1874	Beta-galactosidase
HUI97_11660	COG1570	exodeoxyribonuclease VII activity
HUI97_11665	COG1181	Belongs to the D-alanine--D-alanine ligase family
HUI97_11675	COG0386	Belongs to the glutathione peroxidase family
HUI97_11680	COG0513	Belongs to the DEAD box helicase family
HUI97_11695	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
HUI97_11700	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
HUI97_11705	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
HUI97_11755	COG3300	MHYT domain
HUI97_11755	COG5001	Diguanylate cyclase
HUI97_11770	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HUI97_11780	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
HUI97_11785	COG0563	adenylate kinase activity
HUI97_11795	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
HUI97_11800	COG1286	toxin biosynthetic process
HUI97_11810	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
HUI97_11815	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
HUI97_11820	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
HUI97_11825	COG1674	ftsk spoiiie
HUI97_11825	COG0531	amino acid
HUI97_11835	COG0686	Belongs to the AlaDH PNT family
HUI97_11840	COG0492	ferredoxin-NADP+ reductase activity
HUI97_11845	COG3706	GGDEF domain
HUI97_11850	COG3134	Outer membrane lipoprotein
HUI97_11855	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
HUI97_11860	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
HUI97_11865	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
HUI97_11870	COG0542	response to heat
HUI97_11875	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
HUI97_11880	COG1278	Cold shock
HUI97_11885	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
HUI97_11905	COG0745	RESPONSE REGULATOR receiver
HUI97_11910	COG2205	protein histidine kinase activity
HUI97_11920	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
HUI97_11920	COG0392	lysyltransferase activity
HUI97_11945	COG1435	thymidine kinase activity
HUI97_11950	COG1757	Na H antiporter
HUI97_11955	COG2916	Histone family protein nucleoid-structuring protein H-NS
HUI97_11960	COG2096	Adenosyltransferase
HUI97_11965	COG3530	Putative quorum-sensing-regulated virulence factor
HUI97_11970	COG0602	queuosine metabolic process
HUI97_11975	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
HUI97_11995	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
HUI97_12005	COG0776	regulation of translation
HUI97_12010	COG0539	negative regulation of cytoplasmic translation
HUI97_12015	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
HUI97_12020	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
HUI97_12035	COG2814	Major facilitator Superfamily
HUI97_12050	COG1368	sulfuric ester hydrolase activity
HUI97_12055	COG1619	proteins homologs of microcin C7 resistance protein MccF
HUI97_12060	COG4667	esterase of the alpha-beta hydrolase superfamily
HUI97_12080	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
HUI97_12080	COG1648	precorrin-2 dehydrogenase activity
HUI97_12090	COG0393	Putative heavy-metal-binding
HUI97_12095	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
HUI97_12100	COG0285	dihydrofolate synthase activity
HUI97_12105	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
HUI97_12110	COG0101	tRNA pseudouridine synthase activity
HUI97_12120	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
HUI97_12125	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
HUI97_12130	COG0671	phosphoesterase, PA-phosphatase related
HUI97_12135	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
HUI97_12140	COG2056	Na+-H+ antiporter family
HUI97_12145	COG5001	Diguanylate cyclase
HUI97_12145	COG3300	MHYT domain
HUI97_12155	COG0513	Belongs to the DEAD box helicase family
HUI97_12160	COG2050	protein possibly involved in aromatic compounds catabolism
HUI97_12170	COG0277	FAD linked oxidase domain protein
HUI97_12170	COG0247	lactate metabolic process
HUI97_12180	COG1253	flavin adenine dinucleotide binding
HUI97_12185	COG1902	pentaerythritol trinitrate reductase activity
HUI97_12195	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
HUI97_12200	COG0647	UMP catabolic process
HUI97_12205	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
HUI97_12205	COG4651	solute:proton antiporter activity
HUI97_12215	COG0367	asparagine synthase
HUI97_12225	COG0625	glutathione transferase activity
HUI97_12235	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
HUI97_12250	COG0564	pseudouridine synthase activity
HUI97_12255	COG4160	amino acid transport
HUI97_12265	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HUI97_12275	COG2431	L-lysine efflux transmembrane transporter activity
HUI97_12280	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
HUI97_12285	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HUI97_12290	COG3124	Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP
HUI97_12300	COG1393	Belongs to the ArsC family
HUI97_12310	COG4783	chaperone-mediated protein folding
HUI97_12315	COG0425	Belongs to the sulfur carrier protein TusA family
HUI97_12340	COG3842	ATPase activity
HUI97_12345	COG3833	ABC-type maltose transport systems, permease component
HUI97_12350	COG1175	transmembrane transport
HUI97_12360	COG3081	Nucleoid-associated protein
HUI97_12365	COG3082	Protein of unknown function (DUF1414)
HUI97_12370	COG3083	sulfuric ester hydrolase activity
HUI97_12375	COG1464	Belongs to the NlpA lipoprotein family
HUI97_12390	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HUI97_12390	COG0574	Belongs to the PEP-utilizing enzyme family
HUI97_12395	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
HUI97_12420	COG0840	transmembrane signaling receptor activity
HUI97_12425	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
HUI97_12425	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
HUI97_12430	COG0509	glycine decarboxylation via glycine cleavage system
HUI97_12435	COG0404	The glycine cleavage system catalyzes the degradation of glycine
HUI97_12440	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
HUI97_12445	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
HUI97_12465	COG0243	molybdopterin cofactor binding
HUI97_12470	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
HUI97_12475	COG0583	DNA-binding transcription factor activity
HUI97_12485	COG2814	Major facilitator Superfamily
HUI97_12490	COG0444	Belongs to the ABC transporter superfamily
HUI97_12495	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
HUI97_12500	COG0601	transmembrane transport
HUI97_12510	COG0625	glutathione transferase activity
HUI97_12520	COG0483	inositol monophosphate 1-phosphatase activity
HUI97_12525	COG0840	transmembrane signaling receptor activity
HUI97_12535	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
HUI97_12545	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
HUI97_12570	COG3039	Transposase
HUI97_12590	COG1334	flagellar protein FlaG
HUI97_12610	COG0301	tRNA thio-modification
HUI97_12610	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HUI97_12625	COG4953	penicillin-binding protein 1C
HUI97_12630	COG2373	Large extracellular alpha-helical protein
HUI97_12640	COG0446	pyridine nucleotide-disulphide oxidoreductase
HUI97_12645	COG3300	MHYT domain
HUI97_12645	COG5001	Diguanylate cyclase
HUI97_12650	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HUI97_12660	COG1252	NADH dehydrogenase
HUI97_12665	COG3150	esterase
HUI97_12670	COG2233	PERMEase
HUI97_12680	COG2354	Protein conserved in bacteria
HUI97_12700	COG1301	dicarboxylic acid transport
HUI97_12715	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
HUI97_12730	COG0537	adenosine 5'-monophosphoramidase activity
HUI97_12765	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
HUI97_12770	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
HUI97_12780	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
HUI97_12785	COG1605	Chorismate mutase
HUI97_12785	COG0287	Prephenate dehydrogenase
HUI97_12795	COG1199	ATP-dependent helicase activity
HUI97_12805	COG0123	including yeast histone deacetylase and acetoin utilization protein
HUI97_12810	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
HUI97_12815	COG1785	Belongs to the alkaline phosphatase family
HUI97_12835	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
HUI97_12840	COG2197	response regulator
HUI97_12850	COG2271	Major facilitator Superfamily
HUI97_12855	COG3706	GGDEF domain
HUI97_12860	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HUI97_12865	COG0765	amino acid transport
HUI97_12885	COG0531	amino acid
HUI97_12900	COG1253	flavin adenine dinucleotide binding
HUI97_12905	COG0704	Plays a role in the regulation of phosphate uptake
HUI97_12910	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
HUI97_12915	COG0581	inorganic phosphate transmembrane transporter activity
HUI97_12920	COG0573	inorganic phosphate transmembrane transporter activity
HUI97_12925	COG0590	tRNA wobble adenosine to inosine editing
HUI97_12940	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
HUI97_12965	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
HUI97_12970	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
HUI97_12975	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
HUI97_12980	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
HUI97_13005	COG2716	regulation of RNA biosynthetic process
HUI97_13010	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
HUI97_13020	COG2239	Acts as a magnesium transporter
HUI97_13025	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
HUI97_13040	COG1706	bacterial-type flagellum-dependent cell motility
HUI97_13045	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
HUI97_13055	COG4787	bacterial-type flagellum-dependent cell motility
HUI97_13075	COG1815	bacterial-type flagellum-dependent cell motility
HUI97_13080	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
HUI97_13085	COG0784	Response regulator, receiver
HUI97_13085	COG0835	chemotaxis
HUI97_13090	COG1261	Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly
HUI97_13105	COG0622	Phosphoesterase
HUI97_13110	COG4166	transmembrane transport
HUI97_13125	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
HUI97_13135	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
HUI97_13140	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HUI97_13145	COG1882	Formate acetyltransferase
HUI97_13150	COG1349	DNA-binding transcription factor activity
HUI97_13155	COG4166	transmembrane transport
HUI97_13180	COG1278	Cold shock
HUI97_13205	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HUI97_13205	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
HUI97_13210	COG1028	Short-chain dehydrogenase reductase Sdr
HUI97_13215	COG1535	isochorismatase
HUI97_13215	COG3433	isochorismatase activity
HUI97_13220	COG1021	2,3-dihydroxybenzoate-AMP ligase
HUI97_13225	COG1169	isochorismate synthase
HUI97_13230	COG4771	TonB-dependent receptor
HUI97_13235	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
HUI97_13240	COG1609	Transcriptional regulator
HUI97_13245	COG0741	lytic transglycosylase activity
HUI97_13255	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
HUI97_13275	COG2911	Protein conserved in bacteria
HUI97_13280	COG0729	surface antigen
HUI97_13290	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
HUI97_13300	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
HUI97_13310	COG4134	Bacterial extracellular solute-binding protein
HUI97_13320	COG4136	ATPase activity
HUI97_13325	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HUI97_13330	COG2951	lytic endotransglycosylase activity
HUI97_13345	COG0033	Phosphoglucomutase
HUI97_13350	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
HUI97_13355	COG0596	Alpha beta hydrolase
HUI97_13370	COG0716	FMN binding
HUI97_13380	COG0735	belongs to the Fur family
HUI97_13385	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
HUI97_13395	COG1263	PTS System
HUI97_13395	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HUI97_13395	COG2190	(PTS) system
HUI97_13400	COG0363	glucosamine-6-phosphate deaminase activity
HUI97_13405	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
HUI97_13410	COG1940	carbohydrate kinase activity
HUI97_13410	COG1846	Transcriptional regulator
HUI97_13420	COG2199	diguanylate cyclase activity
HUI97_13420	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
HUI97_13425	COG3275	phosphorelay sensor kinase activity
HUI97_13430	COG3279	Response regulator of the LytR AlgR family
HUI97_13435	COG1966	Carbon starvation protein
HUI97_13445	COG1566	PFAM secretion protein HlyD family protein
HUI97_13450	COG1061	Type III restriction enzyme res subunit
HUI97_13455	COG2027	D-alanyl-D-alanine carboxypeptidase
HUI97_13460	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
HUI97_13465	COG3021	interspecies interaction between organisms
HUI97_13475	COG1607	acyl-coa hydrolase
HUI97_13480	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
HUI97_13490	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
HUI97_13490	COG1013	pyruvate-flavodoxin oxidoreductase activity
HUI97_13490	COG0674	pyruvate-flavodoxin oxidoreductase activity
HUI97_13490	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
HUI97_13505	COG0633	Ferredoxin
HUI97_13505	COG3217	Mosc domain protein beta barrel domain protein
HUI97_13505	COG0633	Ferredoxin
HUI97_13505	COG3217	Mosc domain protein beta barrel domain protein
HUI97_13515	COG0501	Belongs to the peptidase M48B family
HUI97_13520	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
HUI97_13525	COG2226	methyltransferase
HUI97_13525	COG1073	alpha beta
HUI97_13530	COG0156	8-amino-7-oxononanoate synthase activity
HUI97_13535	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
HUI97_13540	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
HUI97_13555	COG0017	Asparaginyl-tRNA synthetase
HUI97_13565	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
HUI97_13575	COG1473	amidohydrolase
HUI97_13580	COG3069	C4-dicarboxylate transmembrane transporter activity
HUI97_13590	COG1393	Belongs to the ArsC family
HUI97_13595	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
HUI97_13600	COG1876	peptidase activity
HUI97_13610	COG3263	regulation of cellular component size
HUI97_13625	COG3385	transposase activity
HUI97_13630	COG1280	lysine exporter protein (LysE YggA)
HUI97_13665	COG0564	pseudouridine synthase activity
HUI97_13675	COG1454	alcohol dehydrogenase
HUI97_13680	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
HUI97_13685	COG0702	epimerase
HUI97_13695	COG0095	Lipoate-protein ligase
HUI97_13705	COG0577	efflux transmembrane transporter activity
HUI97_13705	COG1136	(ABC) transporter
HUI97_13710	COG0577	efflux transmembrane transporter activity
HUI97_13710	COG1136	(ABC) transporter
HUI97_13715	COG0577	efflux transmembrane transporter activity
HUI97_13715	COG1136	(ABC) transporter
HUI97_13720	COG1566	PFAM secretion protein HlyD family protein
HUI97_13755	COG0446	pyridine nucleotide-disulphide oxidoreductase
HUI97_13765	COG1285	pathogenesis
HUI97_13795	COG0484	heat shock protein binding
HUI97_13800	COG0443	Heat shock 70 kDa protein
HUI97_13805	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
HUI97_13810	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
HUI97_13815	COG0497	DNA recombination
HUI97_13820	COG1227	inorganic diphosphatase activity
HUI97_13825	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HUI97_13830	COG1136	(ABC) transporter
HUI97_13830	COG0577	efflux transmembrane transporter activity
HUI97_13850	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
HUI97_13870	COG0489	protein tyrosine kinase activity
HUI97_13870	COG3206	protein involved in exopolysaccharide biosynthesis
HUI97_13895	COG0662	Cupin 2, conserved barrel domain protein
HUI97_13895	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
HUI97_13900	COG1051	belongs to the nudix hydrolase family
HUI97_13905	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
HUI97_13910	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
HUI97_13915	COG1216	Glycosyl transferase, family 2
HUI97_13930	COG0110	maltose O-acetyltransferase activity
HUI97_13945	COG1083	cytidylyl-transferase
HUI97_13960	COG2089	acid synthase
HUI97_13965	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
HUI97_13970	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
HUI97_13980	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
HUI97_13990	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
HUI97_14005	COG2755	lipolytic protein G-D-S-L family
HUI97_14005	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
HUI97_14020	COG1134	teichoic acid transport
HUI97_14025	COG1682	transport, permease protein
HUI97_14040	COG1091	dTDP-4-dehydrorhamnose reductase activity
HUI97_14050	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HUI97_14055	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HUI97_14060	COG1309	transcriptional regulator
HUI97_14075	COG1342	Belongs to the UPF0251 family
HUI97_14095	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
HUI97_14115	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
HUI97_14120	COG0083	homoserine kinase activity
HUI97_14130	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
HUI97_14135	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
HUI97_14140	COG1946	Acyl-CoA thioesterase
HUI97_14155	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
HUI97_14165	COG0009	L-threonylcarbamoyladenylate synthase
HUI97_14175	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
HUI97_14180	COG0512	Glutamine amidotransferase of anthranilate synthase
HUI97_14180	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
HUI97_14185	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
HUI97_14190	COG0134	indole-3-glycerol-phosphate synthase activity
HUI97_14190	COG0135	phosphoribosylanthranilate isomerase activity
HUI97_14195	COG0133	tryptophan synthase activity
HUI97_14200	COG0159	tryptophan synthase activity
HUI97_14215	COG1988	membrane-bound metal-dependent
HUI97_14235	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
HUI97_14245	COG0798	PFAM Bile acid sodium symporter
HUI97_14260	COG0640	Transcriptional regulator
HUI97_14275	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
HUI97_14285	COG0745	RESPONSE REGULATOR receiver
HUI97_14300	COG4988	ABC transporter
HUI97_14305	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
HUI97_14325	COG1720	tRNA m6t6A37 methyltransferase activity
HUI97_14330	COG3038	cytochrome b561
HUI97_14370	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
HUI97_14375	COG1396	sequence-specific DNA binding
HUI97_14375	COG1917	Cupin 2, conserved barrel domain protein
HUI97_14390	COG0531	amino acid
HUI97_14400	COG0531	amino acid
HUI97_14410	COG1283	sodium-dependent phosphate transmembrane transporter activity
HUI97_14425	COG2974	May be involved in recombination
HUI97_14435	COG0420	3'-5' exonuclease activity
HUI97_14440	COG0419	ATPase involved in DNA repair
HUI97_14445	COG3384	dioxygenase
HUI97_14455	COG0469	pyruvate kinase activity
HUI97_14460	COG1196	nuclear chromosome segregation
HUI97_14460	COG3264	Mechanosensitive ion channel
HUI97_14475	COG3706	GGDEF domain
HUI97_14480	COG2190	(PTS) system
HUI97_14490	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
HUI97_14495	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
HUI97_14500	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
HUI97_14515	COG2770	Histidine kinase
HUI97_14515	COG3437	response regulator, receiver
HUI97_14520	COG3267	Type II secretory pathway component ExeA
HUI97_14520	COG3409	Peptidoglycan-binding domain 1 protein
HUI97_14540	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
HUI97_14545	COG1459	type II secretion system
HUI97_14550	COG2165	general secretion pathway protein
HUI97_14565	COG2165	general secretion pathway protein
HUI97_14570	COG4795	General secretion pathway protein
HUI97_14575	COG3156	type II secretion system protein K
HUI97_14585	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
HUI97_14615	COG0670	Belongs to the BI1 family
HUI97_14620	COG1289	transmembrane transporter activity
HUI97_14625	COG2920	part of a sulfur-relay system
HUI97_14630	COG0673	inositol 2-dehydrogenase activity
HUI97_14665	COG1032	radical SAM domain protein
HUI97_14675	COG1566	PFAM secretion protein HlyD family protein
HUI97_14680	COG3706	GGDEF domain
HUI97_14685	COG1752	Esterase of the alpha-beta hydrolase superfamily
HUI97_14690	COG0531	amino acid
HUI97_14720	COG0281	malic enzyme
HUI97_14730	COG0534	Mate efflux family protein
HUI97_14745	COG2233	PERMEase
HUI97_14750	COG0095	Lipoate-protein ligase
HUI97_14755	COG1115	amino acid carrier protein
HUI97_14760	COG0019	diaminopimelate decarboxylase activity
HUI97_14770	COG0678	peroxiredoxin activity
HUI97_14795	COG0545	Peptidyl-prolyl cis-trans isomerase
HUI97_14800	COG3142	Participates in the control of copper homeostasis
HUI97_14825	COG5002	protein histidine kinase activity
HUI97_14830	COG0745	RESPONSE REGULATOR receiver
HUI97_14835	COG0346	lactoylglutathione lyase activity
HUI97_14840	COG3284	Transcriptional regulator
HUI97_14855	COG0697	spore germination
HUI97_14865	COG3290	protein histidine kinase activity
HUI97_14870	COG0281	malic enzyme
HUI97_14880	COG1846	Transcriptional regulator
HUI97_14885	COG1566	PFAM secretion protein HlyD family protein
HUI97_14915	COG0602	queuosine metabolic process
HUI97_14920	COG1328	CTP reductase activity
HUI97_14930	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
HUI97_14935	COG3115	cell septum assembly
HUI97_14940	COG1196	nuclear chromosome segregation
HUI97_14950	COG2860	membrane
HUI97_14960	COG3108	Peptidase M15
HUI97_14965	COG2989	Protein conserved in bacteria
HUI97_14980	COG0463	Glycosyl transferase, family 2
HUI97_14995	COG0366	Alpha amylase catalytic
HUI97_15030	COG2199	diguanylate cyclase activity
HUI97_15030	COG2203	Gaf domain
HUI97_15040	COG3590	peptidase
HUI97_15050	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
HUI97_15055	COG1982	Orn Lys Arg decarboxylase major
HUI97_15060	COG0531	amino acid
HUI97_15065	COG3710	Transcriptional regulator
HUI97_15070	COG0531	amino acid
HUI97_15080	COG1073	alpha beta
HUI97_15085	COG1073	alpha beta
HUI97_15105	COG0814	amino acid
HUI97_15135	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
HUI97_15140	COG0739	heme binding
HUI97_15145	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
HUI97_15165	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
HUI97_15175	COG3091	SprT-like family
HUI97_15185	COG1385	rRNA (uridine-N3-)-methyltransferase activity
HUI97_15190	COG0189	ligase activity
HUI97_15195	COG1678	Uncharacterized ACR, COG1678
HUI97_15200	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
HUI97_15205	COG3104	oligopeptide transport
HUI97_15220	COG0714	Associated with various cellular activities
HUI97_15235	COG1115	amino acid carrier protein
HUI97_15240	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
HUI97_15250	COG0825	malonyl-CoA metabolic process
HUI97_15260	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HUI97_15265	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
HUI97_15270	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
HUI97_15275	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
HUI97_15280	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
HUI97_15295	COG0750	zinc metalloprotease
HUI97_15300	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
HUI97_15305	COG0575	Belongs to the CDS family
HUI97_15310	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
HUI97_15315	COG0233	cytoplasmic translational termination
HUI97_15320	COG0528	UMP kinase activity
HUI97_15325	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
HUI97_15330	COG0052	Belongs to the universal ribosomal protein uS2 family
HUI97_15335	COG0024	Methionine aminopeptidase
HUI97_15340	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
HUI97_15345	COG2171	N-acyltransferase activity
HUI97_15355	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HUI97_15355	COG1263	PTS System
HUI97_15365	COG4580	involved in the transport of maltose and maltodextrins
HUI97_15375	COG0564	pseudouridine synthase activity
HUI97_15380	COG3098	single-species biofilm formation
HUI97_15405	COG5595	Zn-ribbon-containing, possibly nucleic-acid-binding protein (DUF2310)
HUI97_15415	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
HUI97_15415	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
HUI97_15430	COG1611	Belongs to the LOG family
HUI97_15435	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HUI97_15440	COG0473	3-isopropylmalate dehydrogenase activity
HUI97_15450	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
HUI97_15455	COG2363	Small membrane protein
HUI97_15465	COG0583	DNA-binding transcription factor activity
HUI97_15470	COG0840	transmembrane signaling receptor activity
HUI97_15475	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HUI97_15490	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HUI97_15495	COG1666	GTP binding
HUI97_15505	COG2211	Major facilitator Superfamily
HUI97_15510	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
HUI97_15520	COG2813	Specifically methylates the guanine in position
HUI97_15525	COG0271	Belongs to the BolA IbaG family
HUI97_15530	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
HUI97_15535	COG1805	sodium ion transport
HUI97_15540	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
HUI97_15545	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
HUI97_15550	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
HUI97_15555	COG2871	sodium ion transport
HUI97_15560	COG1477	protein flavinylation
HUI97_15590	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
HUI97_15605	COG0300	oxidoreductase activity
HUI97_15615	COG0415	Belongs to the DNA photolyase family
HUI97_15620	COG0789	Transcriptional regulator
HUI97_15625	COG3272	Protein of unknown function (DUF1722)
HUI97_15655	COG1605	Chorismate mutase
HUI97_15655	COG0077	Prephenate dehydratase
HUI97_15685	COG0840	transmembrane signaling receptor activity
HUI97_15695	COG0300	oxidoreductase activity
HUI97_15720	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
HUI97_15760	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
HUI97_15765	COG0826	peptidase U32
HUI97_15770	COG1280	lysine exporter protein (LysE YggA)
HUI97_15780	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HUI97_15790	COG0745	RESPONSE REGULATOR receiver
HUI97_15800	COG0643	Histidine kinase
HUI97_15800	COG2198	Histidine kinase
HUI97_15810	COG0835	chemotaxis
HUI97_15815	COG0840	transmembrane signaling receptor activity
HUI97_15825	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
HUI97_15830	COG2201	protein-glutamate methylesterase activity
HUI97_15835	COG1185	polyribonucleotide nucleotidyltransferase activity
HUI97_15840	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
HUI97_15845	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
HUI97_15850	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
HUI97_15855	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
HUI97_15860	COG0195	Participates in both transcription termination and antitermination
HUI97_15865	COG0779	Required for maturation of 30S ribosomal subunits
HUI97_15880	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
HUI97_15885	COG0149	triose-phosphate isomerase activity
HUI97_15890	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
HUI97_15895	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
HUI97_15905	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
HUI97_15910	COG1534	Rna-binding protein
HUI97_15925	COG1360	Flagellar Motor Protein
HUI97_15930	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
HUI97_15935	COG1722	exodeoxyribonuclease VII activity
HUI97_15940	COG0142	geranyltranstransferase activity
HUI97_15945	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
HUI97_15950	COG0737	Belongs to the 5'-nucleotidase family
HUI97_15970	COG2204	response regulator
HUI97_15975	COG0545	Peptidyl-prolyl cis-trans isomerase
HUI97_15985	COG2900	Belongs to the SlyX family
HUI97_15995	COG0601	transmembrane transport
HUI97_16010	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
HUI97_16015	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
HUI97_16020	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
HUI97_16025	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
HUI97_16040	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
HUI97_16040	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
HUI97_16045	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
HUI97_16050	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
HUI97_16060	COG2205	protein histidine kinase activity
HUI97_16060	COG2198	Histidine kinase
HUI97_16060	COG0784	Response regulator, receiver
HUI97_16065	COG1879	ABC-type sugar transport system periplasmic component
HUI97_16075	COG0745	RESPONSE REGULATOR receiver
HUI97_16080	COG3005	denitrification pathway
HUI97_16090	COG3381	protein complex oligomerization
HUI97_16110	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
HUI97_16115	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
HUI97_16120	COG0511	ligase activity, forming carbon-carbon bonds
HUI97_16125	COG0439	Biotin carboxylase
HUI97_16135	COG4145	pantothenate transmembrane transporter activity
HUI97_16140	COG2190	(PTS) system
HUI97_16140	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HUI97_16140	COG1263	PTS System
HUI97_16145	COG0583	DNA-binding transcription factor activity
HUI97_16150	COG0604	alcohol dehydrogenase
HUI97_16155	COG2264	protein methyltransferase activity
HUI97_16165	COG0778	Nitroreductase
HUI97_16170	COG0446	pyridine nucleotide-disulphide oxidoreductase
HUI97_16170	COG1902	pentaerythritol trinitrate reductase activity
HUI97_16175	COG0616	signal peptide processing
HUI97_16195	COG0848	biopolymer transport protein
HUI97_16200	COG0811	peptide transport
HUI97_16205	COG0811	peptide transport
HUI97_16220	COG4174	ABC transporter (Permease)
HUI97_16225	COG4239	(ABC) transporter, permease
HUI97_16235	COG0444	Belongs to the ABC transporter superfamily
HUI97_16240	COG4608	Belongs to the ABC transporter superfamily
HUI97_16260	COG3416	Protein conserved in bacteria
HUI97_16270	COG0741	lytic transglycosylase activity
HUI97_16285	COG0488	(ABC) transporter
HUI97_16295	COG2252	PERMEase
HUI97_16300	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
HUI97_16305	COG0840	transmembrane signaling receptor activity
HUI97_16315	COG1278	Cold shock
HUI97_16355	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
HUI97_16360	COG1162	GTPase activity
HUI97_16365	COG0688	phosphatidylethanolamine metabolic process
HUI97_16370	COG4628	conserved protein (DUF2132)
HUI97_16385	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
HUI97_16400	COG1073	alpha beta
HUI97_16405	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
HUI97_16410	COG2195	Cleaves the N-terminal amino acid of tripeptides
HUI97_16415	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
HUI97_16420	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
HUI97_16425	COG3178	'Phosphotransferase
HUI97_16430	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
HUI97_16435	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
HUI97_16440	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
HUI97_16445	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
HUI97_16450	COG2967	ApaG domain
HUI97_16455	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
HUI97_16470	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HUI97_16480	COG3314	Sporulation integral membrane protein YlbJ
HUI97_16485	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
HUI97_16490	COG0211	Belongs to the bacterial ribosomal protein bL27 family
HUI97_16495	COG0261	This protein binds to 23S rRNA in the presence of protein L20
HUI97_16500	COG0142	geranyltranstransferase activity
HUI97_16505	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
HUI97_16510	COG0330	HflC and HflK could
HUI97_16515	COG0330	HflC and HflK could
HUI97_16520	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
HUI97_16525	COG1923	regulation of RNA biosynthetic process
HUI97_16530	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
HUI97_16535	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
HUI97_16540	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
HUI97_16550	COG0802	atpase or kinase
HUI97_16555	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
HUI97_16555	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
HUI97_16575	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
HUI97_16580	COG2011	ABC-type metal ion transport system permease component
HUI97_16585	COG1464	Belongs to the NlpA lipoprotein family
HUI97_16595	COG0840	transmembrane signaling receptor activity
HUI97_16615	COG0232	Belongs to the dGTPase family. Type 2 subfamily
HUI97_16620	COG2198	Histidine kinase
HUI97_16620	COG0784	Response regulator, receiver
HUI97_16620	COG5002	protein histidine kinase activity
HUI97_16655	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
HUI97_16660	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
HUI97_16665	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HUI97_16670	COG2716	regulation of RNA biosynthetic process
HUI97_16675	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
HUI97_16680	COG3013	Belongs to the UPF0304 family
HUI97_16690	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HUI97_16695	COG0280	phosphate acetyltransferase
HUI97_16695	COG0857	belongs to the CobB CobQ family
HUI97_16700	COG1555	photosystem II stabilization
HUI97_16705	COG1210	Utp--glucose-1-phosphate uridylyltransferase
HUI97_16710	COG3104	oligopeptide transport
HUI97_16715	COG0745	RESPONSE REGULATOR receiver
HUI97_16745	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HUI97_16760	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
HUI97_16795	COG0440	acetolactate synthase activity
HUI97_16800	COG0028	Belongs to the TPP enzyme family
HUI97_16825	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
HUI97_16830	COG0473	3-isopropylmalate dehydrogenase activity
HUI97_16835	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
HUI97_16840	COG0066	3-isopropylmalate dehydratase activity
HUI97_16855	COG4143	(ABC) transporter
HUI97_16860	COG1178	ABC-type Fe3 transport system permease component
HUI97_16865	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
HUI97_16870	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
HUI97_16920	COG0459	protein refolding
HUI97_16925	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
HUI97_16930	COG0534	Mate efflux family protein
HUI97_16935	COG3030	protein affecting phage T7 exclusion by the F plasmid
HUI97_16940	COG1027	Aspartate ammonia-lyase
HUI97_16945	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
HUI97_16950	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
HUI97_16955	COG0828	Belongs to the bacterial ribosomal protein bS21 family
HUI97_16960	COG1610	YqeY-like protein
HUI97_16970	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HUI97_16990	COG0151	Belongs to the GarS family
HUI97_16995	COG0138	bifunctional purine biosynthesis protein purh
HUI97_17005	COG3036	rescue of stalled ribosome
HUI97_17010	COG0635	Involved in the biosynthesis of porphyrin-containing compound
HUI97_17015	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
HUI97_17025	COG0673	inositol 2-dehydrogenase activity
HUI97_17035	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HUI97_17040	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HUI97_17050	COG0583	DNA-binding transcription factor activity
HUI97_17055	COG0477	Major facilitator Superfamily
HUI97_17075	COG1028	Short-chain dehydrogenase reductase Sdr
HUI97_17100	COG0456	acetyltransferase
HUI97_17110	COG1022	Amp-dependent synthetase and ligase
HUI97_17120	COG2918	glutathione biosynthetic process
HUI97_17125	COG0612	Peptidase, M16
HUI97_17130	COG1238	metal cluster binding
HUI97_17135	COG1064	alcohol dehydrogenase
HUI97_17160	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
HUI97_17165	COG0359	binds to the 23S rRNA
HUI97_17170	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
HUI97_17175	COG0360	Binds together with S18 to 16S ribosomal RNA
HUI97_17180	COG1914	H( )-stimulated, divalent metal cation uptake system
HUI97_17185	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
HUI97_17195	COG0776	regulation of translation
HUI97_17210	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
HUI97_17225	COG0560	Phosphoserine phosphatase
HUI97_17235	COG0813	purine-nucleoside phosphorylase activity
HUI97_17240	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
HUI97_17245	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
HUI97_17250	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
HUI97_17260	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
HUI97_17265	COG0084	hydrolase, TatD family'
HUI97_17270	COG2165	general secretion pathway protein
HUI97_17280	COG1854	S-ribosylhomocysteine lyase activity
HUI97_17295	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
HUI97_17295	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
HUI97_17340	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
HUI97_17345	COG1047	Peptidyl-prolyl cis-trans
HUI97_17350	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
HUI97_17355	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
HUI97_17360	COG0196	riboflavin kinase activity
HUI97_17365	COG0728	peptidoglycan biosynthetic process
HUI97_17370	COG0268	Binds directly to 16S ribosomal RNA
HUI97_17375	COG0640	Transcriptional regulator
HUI97_17380	COG0583	DNA-binding transcription factor activity
HUI97_17390	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
HUI97_17395	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
HUI97_17400	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
HUI97_17410	COG1051	belongs to the nudix hydrolase family
HUI97_17415	COG3066	DNA modification
HUI97_17425	COG0335	large ribosomal subunit rRNA binding
HUI97_17430	COG0336	Belongs to the RNA methyltransferase TrmD family
HUI97_17435	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
HUI97_17440	COG0228	four-way junction DNA binding
HUI97_17445	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
HUI97_17450	COG4137	Cytochrome C assembly protein
HUI97_17455	COG4536	flavin adenine dinucleotide binding
HUI97_17465	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
HUI97_17465	COG1017	nitric oxide dioxygenase activity
HUI97_17470	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
HUI97_17475	COG0039	L-malate dehydrogenase activity
HUI97_17480	COG4160	amino acid transport
HUI97_17485	COG4215	(ABC) transporter
HUI97_17490	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HUI97_17495	COG1126	abc transporter atp-binding protein
HUI97_17500	COG1438	arginine binding
HUI97_17505	COG2837	iron assimilation
HUI97_17510	COG3842	ATPase activity
HUI97_17520	COG1840	ABC-type Fe3 transport system, periplasmic component
HUI97_17525	COG0347	Belongs to the P(II) protein family
HUI97_17545	COG3022	response to hydroperoxide
HUI97_17560	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
HUI97_17565	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HUI97_17570	COG0762	integral membrane protein
HUI97_17575	COG1872	DUF167
HUI97_17585	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
HUI97_17590	COG0583	DNA-binding transcription factor activity
HUI97_17605	COG1929	Belongs to the glycerate kinase type-1 family
HUI97_17610	COG2610	gluconate transmembrane transporter activity
HUI97_17615	COG3835	regulator
HUI97_17625	COG3112	Uncharacterised protein family (UPF0231)
HUI97_17645	COG3568	Endonuclease Exonuclease Phosphatase
HUI97_17655	COG0513	Belongs to the DEAD box helicase family
HUI97_17695	COG1448	Aminotransferase
HUI97_17710	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HUI97_17715	COG1328	CTP reductase activity
HUI97_17740	COG0633	Ferredoxin
HUI97_17740	COG0543	2 iron, 2 sulfur cluster binding
HUI97_17755	COG0840	transmembrane signaling receptor activity
HUI97_17760	COG3397	chitin binding
HUI97_17765	COG3174	membrane
HUI97_17770	COG0110	maltose O-acetyltransferase activity
HUI97_17785	COG1011	Hydrolase
HUI97_17790	COG0494	nUDIX hydrolase
HUI97_17795	COG1218	3'(2'),5'-bisphosphate nucleotidase
HUI97_17800	COG0814	amino acid
HUI97_17805	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HUI97_17820	COG0626	cystathionine gamma-synthase activity
HUI97_17825	COG0527	aspartate kinase activity
HUI97_17825	COG0460	homoserine dehydrogenase
HUI97_17830	COG0306	phosphate transporter
HUI97_17835	COG1392	Phosphate transport regulator
HUI97_17845	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HUI97_17850	COG2813	Specifically methylates the guanine in position
HUI97_17855	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
HUI97_17860	COG0297	glycogen (starch) synthase activity
HUI97_17900	COG1757	Na H antiporter
HUI97_17905	COG0316	Belongs to the HesB IscA family
HUI97_17915	COG0038	chloride channel
HUI97_17920	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
HUI97_17935	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
HUI97_17935	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
HUI97_17975	COG1396	sequence-specific DNA binding
HUI97_17980	COG3135	benzoate transporter
HUI97_18005	COG0840	transmembrane signaling receptor activity
HUI97_18020	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
HUI97_18055	COG2197	response regulator
HUI97_18090	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
HUI97_18120	COG1396	sequence-specific DNA binding
HUI97_18135	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
HUI97_18145	COG1278	Cold shock
HUI97_18150	COG2252	PERMEase
HUI97_18155	COG2376	Dihydroxyacetone kinase
HUI97_18160	COG1461	Dihydroxyacetone kinase
HUI97_18165	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
HUI97_18165	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
HUI97_18165	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HUI97_18175	COG3284	Transcriptional regulator
HUI97_18185	COG0628	permease
HUI97_18205	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
HUI97_18210	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
HUI97_18230	COG0456	acetyltransferase
HUI97_18235	COG3133	Outer membrane lipoprotein
HUI97_18240	COG0004	ammonium transporteR
HUI97_18245	COG3706	GGDEF domain
HUI97_18255	COG3932	Exopolysaccharide synthesis, ExoD
HUI97_18260	COG0814	amino acid
HUI97_18275	COG0110	maltose O-acetyltransferase activity
HUI97_18280	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
HUI97_18290	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
HUI97_18295	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
HUI97_18305	COG0137	argininosuccinate synthase activity
HUI97_18310	COG0165	Argininosuccinate lyase
HUI97_18330	COG3314	Sporulation integral membrane protein YlbJ
HUI97_18355	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
HUI97_18360	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
HUI97_18375	COG0477	Major facilitator Superfamily
HUI97_18380	COG0523	cobalamin synthesis protein
HUI97_18390	COG1280	lysine exporter protein (LysE YggA)
HUI97_18400	COG2200	EAL domain
HUI97_18405	COG1049	propionate catabolic process, 2-methylcitrate cycle
HUI97_18410	COG1752	Esterase of the alpha-beta hydrolase superfamily
HUI97_18415	COG0840	transmembrane signaling receptor activity
HUI97_18425	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
HUI97_18430	COG0508	dehydrogenase complex catalyzes the overall conversion of
HUI97_18435	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
HUI97_18440	COG2186	Transcriptional regulator
HUI97_18465	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
HUI97_18470	COG1459	type II secretion system
HUI97_18485	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
HUI97_18490	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
HUI97_18495	COG0494	nUDIX hydrolase
HUI97_18500	COG0653	protein targeting
HUI97_18510	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
HUI97_18515	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
HUI97_18520	COG0849	cell division
HUI97_18530	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
HUI97_18535	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
HUI97_18540	COG0772	Belongs to the SEDS family
HUI97_18545	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
HUI97_18550	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
HUI97_18555	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
HUI97_18565	COG0768	penicillin binding
HUI97_18570	COG3116	cell division
HUI97_18575	COG0275	rRNA processing
HUI97_18580	COG2001	Belongs to the MraZ family
HUI97_18590	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
HUI97_18595	COG3107	peptidoglycan biosynthetic process
HUI97_18600	COG0792	nuclease activity
HUI97_18605	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
HUI97_18610	COG2823	Periplasmic or secreted lipoprotein
HUI97_18615	COG2969	positive regulation of protein catabolic process
HUI97_18620	COG0625	glutathione transferase activity
HUI97_18625	COG2857	Cytochrome c1
HUI97_18630	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
HUI97_18635	COG0723	plastoquinol--plastocyanin reductase activity
HUI97_18640	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
HUI97_18645	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
HUI97_18650	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
HUI97_18660	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HUI97_18665	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HUI97_18695	COG3964	amidohydrolase
HUI97_18710	COG3711	transcriptional antiterminator
HUI97_18710	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
HUI97_18715	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
HUI97_18720	COG1660	Displays ATPase and GTPase activities
HUI97_18725	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
HUI97_18740	COG1137	ATPase activity
HUI97_18745	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
HUI97_18750	COG3117	lipopolysaccharide transmembrane transporter activity
HUI97_18755	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
HUI97_18760	COG0517	IMP dehydrogenase activity
HUI97_18760	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
HUI97_18765	COG1127	ABC transporter
HUI97_18770	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
HUI97_18775	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
HUI97_18780	COG2854	intermembrane phospholipid transfer
HUI97_18790	COG5007	Belongs to the BolA IbaG family
HUI97_18795	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HUI97_18800	COG0312	modulator of DNA gyrase
HUI97_18805	COG3028	Belongs to the UPF0307 family
HUI97_18810	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
HUI97_18830	COG1011	Hydrolase
HUI97_18845	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
HUI97_18850	COG0019	diaminopimelate decarboxylase activity
HUI97_18860	COG1965	Belongs to the frataxin family
HUI97_18865	COG0400	carboxylic ester hydrolase activity
HUI97_18870	COG3072	Adenylate cyclase
HUI97_18875	COG0181	hydroxymethylbilane synthase activity
HUI97_18885	COG2959	enzyme of heme biosynthesis
HUI97_18900	COG1494	fructose-1,6-bisphosphatase
HUI97_18955	COG0795	lipopolysaccharide-transporting ATPase activity
HUI97_18960	COG0795	lipopolysaccharide-transporting ATPase activity
HUI97_18965	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
HUI97_18970	COG2927	DNA polymerase III (CHI subunit)
HUI97_18995	COG0456	acetyltransferase
HUI97_18995	COG0454	-acetyltransferase
HUI97_19000	COG0753	catalase activity
HUI97_19025	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
HUI97_19030	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
HUI97_19035	COG5380	lipid catabolic process
HUI97_19055	COG4533	DNA binding
HUI97_19065	COG2873	o-acetylhomoserine
HUI97_19095	COG3842	ATPase activity
HUI97_19105	COG1176	ABC-type spermidine putrescine transport system, permease component I
HUI97_19150	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
HUI97_19155	COG1074	ATP-dependent DNA helicase activity
HUI97_19160	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
HUI97_19165	COG2259	Doxx family
HUI97_19170	COG1741	Belongs to the pirin family
HUI97_19180	COG0583	DNA-binding transcription factor activity
HUI97_19190	COG0840	transmembrane signaling receptor activity
HUI97_19210	COG3706	GGDEF domain
HUI97_19215	COG4771	TonB-dependent receptor
HUI97_19250	COG0203	ribosomal protein L17
HUI97_19255	COG0202	RNA polymerase activity
HUI97_19260	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
HUI97_19265	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
HUI97_19270	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
HUI97_19275	COG0257	Belongs to the bacterial ribosomal protein bL36 family
HUI97_19280	COG0201	protein transport
HUI97_19285	COG0200	Binds to the 23S rRNA
HUI97_19290	COG1841	ribosomal large subunit assembly
HUI97_19295	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
HUI97_19300	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
HUI97_19305	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
HUI97_19310	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
HUI97_19315	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
HUI97_19320	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
HUI97_19325	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
HUI97_19330	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
HUI97_19335	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
HUI97_19340	COG0255	Belongs to the universal ribosomal protein uL29 family
HUI97_19345	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
HUI97_19350	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
HUI97_19355	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
HUI97_19360	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
HUI97_19365	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
HUI97_19370	COG0089	rRNA binding
HUI97_19375	COG0088	Forms part of the polypeptide exit tunnel
HUI97_19380	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
HUI97_19385	COG0051	transcription antitermination factor activity, RNA binding
HUI97_19405	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
HUI97_19410	COG2183	response to ionizing radiation
HUI97_19430	COG0596	Alpha beta hydrolase
HUI97_19435	COG1040	competence protein
HUI97_19440	COG0316	Belongs to the HesB IscA family
HUI97_19440	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
HUI97_19445	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
HUI97_19450	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
HUI97_19455	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HUI97_19460	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
HUI97_19465	COG4942	peptidase
HUI97_19475	COG1609	Transcriptional regulator
HUI97_19480	COG0800	Aldolase
HUI97_19490	COG3265	gluconokinase activity
HUI97_19495	COG2610	gluconate transmembrane transporter activity
HUI97_19500	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HUI97_19505	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
HUI97_19515	COG0456	acetyltransferase
HUI97_19520	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
HUI97_19525	COG1490	D-aminoacyl-tRNA deacylase activity
HUI97_19530	COG1295	ribonuclease BN
HUI97_19535	COG0281	malic enzyme
HUI97_19540	COG0814	amino acid
HUI97_19545	COG0702	epimerase
HUI97_19555	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
HUI97_19560	COG0254	rRNA binding
HUI97_19575	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
HUI97_19580	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
HUI97_19590	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
HUI97_19600	COG0514	ATP-dependent DNA helicase (RecQ)
HUI97_19605	COG2050	protein possibly involved in aromatic compounds catabolism
HUI97_19620	COG2258	MOSC domain
HUI97_19625	COG1177	transmembrane transport
HUI97_19630	COG1176	ABC-type spermidine putrescine transport system, permease component I
HUI97_19635	COG3842	ATPase activity
HUI97_19655	COG0174	glutamine synthetase
HUI97_19675	COG3045	CreA protein
HUI97_19680	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HUI97_19685	COG0443	Heat shock 70 kDa protein
HUI97_19700	COG0366	Alpha amylase catalytic
HUI97_19715	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HUI97_19725	COG4211	Belongs to the binding-protein-dependent transport system permease family
HUI97_19730	COG1129	ABC transporter
HUI97_19740	COG3250	beta-galactosidase activity
HUI97_19745	COG1609	Transcriptional regulator
HUI97_19750	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
HUI97_19755	COG1085	galactose-1-phosphate uridylyltransferase
HUI97_19760	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
HUI97_19765	COG2017	converts alpha-aldose to the beta-anomer
HUI97_19770	COG1968	undecaprenyl-diphosphatase activity
HUI97_19785	COG1595	DNA-templated transcription, initiation
HUI97_19795	COG0018	arginyl-trna synthetase
HUI97_19805	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
HUI97_19810	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
HUI97_19820	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HUI97_19825	COG1131	(ABC) transporter
HUI97_19830	COG0842	Transport permease protein
HUI97_19835	COG0842	Transport permease protein
HUI97_19840	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
HUI97_19850	COG2116	formate transmembrane transporter activity
HUI97_19855	COG1648	precorrin-2 dehydrogenase activity
HUI97_19855	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
HUI97_19860	COG2239	Acts as a magnesium transporter
HUI97_19870	COG0737	Belongs to the 5'-nucleotidase family
HUI97_19875	COG1079	Belongs to the binding-protein-dependent transport system permease family
HUI97_19880	COG4603	Belongs to the binding-protein-dependent transport system permease family
HUI97_19885	COG3845	ABC transporter
HUI97_19890	COG1744	ABC transporter substrate-binding protein PnrA-like
HUI97_19895	COG0210	DNA helicase
HUI97_19905	COG3039	Transposase
HUI97_19925	COG1943	Transposase
HUI97_19965	COG1280	lysine exporter protein (LysE YggA)
HUI97_19990	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
HUI97_20040	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
HUI97_20045	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
HUI97_20050	COG1739	Uncharacterized protein family UPF0029
HUI97_20055	COG0006	proline dipeptidase activity
HUI97_20060	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
HUI97_20065	COG1024	Enoyl-CoA hydratase
HUI97_20065	COG1250	3-hydroxyacyl-CoA dehydrogenase
HUI97_20070	COG0183	Belongs to the thiolase family
HUI97_20095	COG0425	Belongs to the sulfur carrier protein TusA family
HUI97_20100	COG0251	oxidation-reduction process
HUI97_20105	COG2885	chlorophyll binding
HUI97_20110	COG2818	Glycosylase
HUI97_20115	COG0752	glycyl-tRNA synthetase alpha subunit
HUI97_20120	COG0751	glycine-tRNA ligase activity
HUI97_20125	COG3039	Transposase
HUI97_20155	COG1609	Transcriptional regulator
HUI97_20185	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HUI97_20200	COG2960	long-chain fatty acid transporting porin activity
HUI97_20205	COG5001	Diguanylate cyclase
HUI97_20215	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
HUI97_20230	COG3118	belongs to the thioredoxin family
HUI97_20235	COG0513	Belongs to the DEAD box helicase family
HUI97_20240	COG0248	Ppx GppA phosphatase
HUI97_20250	COG0742	ribosomal rna small subunit methyltransferase
HUI97_20265	COG3469	chitinase activity
HUI97_20280	COG0084	hydrolase, TatD family'
HUI97_20285	COG0805	protein transport
HUI97_20290	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
HUI97_20295	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
HUI97_20300	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
HUI97_20305	COG3165	ubiquinone biosynthetic process from chorismate
HUI97_20310	COG2226	methyltransferase
HUI97_20315	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HUI97_20320	COG0402	S-adenosylhomocysteine deaminase activity
HUI97_20325	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
HUI97_20365	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
HUI97_20370	COG0848	biopolymer transport protein
HUI97_20375	COG0811	peptide transport
HUI97_20380	COG0811	peptide transport
HUI97_20390	COG2771	luxR family
HUI97_20395	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
HUI97_20400	COG1349	DNA-binding transcription factor activity
HUI97_20405	COG0745	RESPONSE REGULATOR receiver
HUI97_20410	COG2205	protein histidine kinase activity
HUI97_20420	COG4452	Inner membrane protein CreD
HUI97_20425	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
HUI97_20430	COG0355	proton-transporting ATP synthase activity, rotational mechanism
HUI97_20435	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
HUI97_20440	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
HUI97_20445	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
HUI97_20450	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HUI97_20455	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
HUI97_20465	COG0356	it plays a direct role in the translocation of protons across the membrane
HUI97_20475	COG1475	DNA binding
HUI97_20480	COG1192	Involved in chromosome partitioning
HUI97_20485	COG0357	Ribosomal RNA small subunit methyltransferase G
HUI97_20490	COG0445	tRNA wobble uridine modification
HUI97_20495	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
HUI97_20505	COG4615	Cyclic peptide transporter
HUI97_20510	COG1120	ATPase activity
HUI97_20515	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
HUI97_20525	COG3550	peptidyl-serine autophosphorylation
HUI97_20550	COG0732	type I restriction modification DNA specificity domain
HUI97_20580	COG4974	Belongs to the 'phage' integrase family
HUI97_20585	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
HUI97_20590	COG0706	membrane insertase activity
HUI97_20595	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
HUI97_20600	COG0594	ribonuclease P activity
HUI97_20605	COG0230	Belongs to the bacterial ribosomal protein bL34 family
HUI97_20610	COG1126	abc transporter atp-binding protein