locus-tag	class	description
J6598_00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
J6598_00010	COG0592	DNA-directed DNA polymerase activity
J6598_00025	COG3385	transposase activity
J6598_00035	COG2378	regulation of single-species biofilm formation
J6598_00045	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
J6598_00050	COG0071	Belongs to the small heat shock protein (HSP20) family
J6598_00055	COG0071	Belongs to the small heat shock protein (HSP20) family
J6598_00060	COG3977	Valine--pyruvate aminotransferase
J6598_00075	COG2814	Major facilitator Superfamily
J6598_00080	COG0745	RESPONSE REGULATOR receiver
J6598_00085	COG2205	protein histidine kinase activity
J6598_00105	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
J6598_00110	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
J6598_00110	COG4191	Histidine kinase
J6598_00115	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
J6598_00120	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
J6598_00125	COG1309	transcriptional regulator
J6598_00155	COG0561	phosphatase activity
J6598_00160	COG2267	carboxylic ester hydrolase activity
J6598_00165	COG0110	maltose O-acetyltransferase activity
J6598_00170	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
J6598_00175	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
J6598_00180	COG1758	RNA polymerase activity
J6598_00185	COG0194	GDP metabolic process
J6598_00190	COG0859	PFAM glycosyl transferase family 9
J6598_00195	COG3642	lipopolysaccharide core region biosynthetic process
J6598_00235	COG0589	response to stress
J6598_00240	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
J6598_00245	COG1528	Iron-storage protein
J6598_00250	COG2081	HI0933 family
J6598_00255	COG3275	phosphorelay sensor kinase activity
J6598_00260	COG3279	Response regulator of the LytR AlgR family
J6598_00265	COG2223	nitrite transmembrane transporter activity
J6598_00270	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
J6598_00275	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
J6598_00290	COG0583	DNA-binding transcription factor activity
J6598_00300	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
J6598_00330	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
J6598_00335	COG2166	iron-sulfur cluster assembly
J6598_00340	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
J6598_00355	COG3245	cytochrome
J6598_00360	COG1063	alcohol dehydrogenase
J6598_00375	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
J6598_00385	COG3307	-O-antigen
J6598_00425	COG1280	lysine exporter protein (LysE YggA)
J6598_00460	COG1943	Transposase
J6598_00465	COG0210	DNA helicase
J6598_00470	COG1744	ABC transporter substrate-binding protein PnrA-like
J6598_00475	COG3845	ABC transporter
J6598_00480	COG4603	Belongs to the binding-protein-dependent transport system permease family
J6598_00485	COG1079	Belongs to the binding-protein-dependent transport system permease family
J6598_00490	COG0737	Belongs to the 5'-nucleotidase family
J6598_00500	COG2239	Acts as a magnesium transporter
J6598_00505	COG1648	precorrin-2 dehydrogenase activity
J6598_00505	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
J6598_00510	COG2116	formate transmembrane transporter activity
J6598_00520	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
J6598_00525	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
J6598_00530	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
J6598_00540	COG0018	arginyl-trna synthetase
J6598_00550	COG1595	DNA-templated transcription, initiation
J6598_00560	COG1968	undecaprenyl-diphosphatase activity
J6598_00565	COG2017	converts alpha-aldose to the beta-anomer
J6598_00570	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
J6598_00575	COG1085	galactose-1-phosphate uridylyltransferase
J6598_00580	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
J6598_00585	COG1609	Transcriptional regulator
J6598_00590	COG3250	beta-galactosidase activity
J6598_00600	COG1129	ABC transporter
J6598_00605	COG4211	Belongs to the binding-protein-dependent transport system permease family
J6598_00615	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
J6598_00630	COG0366	Alpha amylase catalytic
J6598_00645	COG0443	Heat shock 70 kDa protein
J6598_00650	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
J6598_00655	COG3045	CreA protein
J6598_00675	COG0174	glutamine synthetase
J6598_00695	COG3842	ATPase activity
J6598_00700	COG1176	ABC-type spermidine putrescine transport system, permease component I
J6598_00705	COG1177	transmembrane transport
J6598_00710	COG2258	MOSC domain
J6598_00725	COG2050	protein possibly involved in aromatic compounds catabolism
J6598_00730	COG0514	ATP-dependent DNA helicase (RecQ)
J6598_00740	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
J6598_00750	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
J6598_00755	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
J6598_00770	COG0254	rRNA binding
J6598_00775	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
J6598_00785	COG0702	epimerase
J6598_00790	COG0814	amino acid
J6598_00795	COG0281	malic enzyme
J6598_00800	COG1295	ribonuclease BN
J6598_00805	COG1490	D-aminoacyl-tRNA deacylase activity
J6598_00810	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
J6598_00815	COG0456	acetyltransferase
J6598_00825	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
J6598_00830	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
J6598_00835	COG2610	gluconate transmembrane transporter activity
J6598_00840	COG3265	gluconokinase activity
J6598_00850	COG0800	Aldolase
J6598_00855	COG1609	Transcriptional regulator
J6598_00865	COG4942	peptidase
J6598_00870	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
J6598_00875	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
J6598_00880	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
J6598_00885	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
J6598_00890	COG0316	Belongs to the HesB IscA family
J6598_00890	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
J6598_00895	COG1040	competence protein
J6598_00900	COG0596	Alpha beta hydrolase
J6598_00920	COG2183	response to ionizing radiation
J6598_00925	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
J6598_00945	COG0051	transcription antitermination factor activity, RNA binding
J6598_00950	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
J6598_00955	COG0088	Forms part of the polypeptide exit tunnel
J6598_00960	COG0089	rRNA binding
J6598_00965	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
J6598_00970	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
J6598_00975	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
J6598_00980	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
J6598_00985	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
J6598_00990	COG0255	Belongs to the universal ribosomal protein uL29 family
J6598_00995	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
J6598_01000	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
J6598_01005	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
J6598_01010	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
J6598_01015	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
J6598_01020	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
J6598_01025	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
J6598_01030	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
J6598_01035	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
J6598_01040	COG1841	ribosomal large subunit assembly
J6598_01045	COG0200	Binds to the 23S rRNA
J6598_01050	COG0201	protein transport
J6598_01055	COG0257	Belongs to the bacterial ribosomal protein bL36 family
J6598_01060	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
J6598_01065	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
J6598_01070	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
J6598_01075	COG0202	RNA polymerase activity
J6598_01080	COG0203	ribosomal protein L17
J6598_01120	COG4771	TonB-dependent receptor
J6598_01125	COG3706	GGDEF domain
J6598_01155	COG0583	DNA-binding transcription factor activity
J6598_01165	COG1741	Belongs to the pirin family
J6598_01170	COG2259	Doxx family
J6598_01175	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
J6598_01180	COG1074	ATP-dependent DNA helicase activity
J6598_01185	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
J6598_01230	COG1175	transmembrane transport
J6598_01240	COG3842	ATPase activity
J6598_01270	COG2873	o-acetylhomoserine
J6598_01280	COG4533	DNA binding
J6598_01300	COG5380	lipid catabolic process
J6598_01305	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
J6598_01310	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
J6598_01335	COG0456	acetyltransferase
J6598_01335	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
J6598_01340	COG0753	catalase activity
J6598_01345	COG0456	acetyltransferase
J6598_01345	COG0454	-acetyltransferase
J6598_01370	COG2927	DNA polymerase III (CHI subunit)
J6598_01375	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
J6598_01380	COG0795	lipopolysaccharide-transporting ATPase activity
J6598_01385	COG0795	lipopolysaccharide-transporting ATPase activity
J6598_01440	COG1494	fructose-1,6-bisphosphatase
J6598_01455	COG2959	enzyme of heme biosynthesis
J6598_01465	COG0181	hydroxymethylbilane synthase activity
J6598_01470	COG3072	Adenylate cyclase
J6598_01475	COG0400	carboxylic ester hydrolase activity
J6598_01480	COG1965	Belongs to the frataxin family
J6598_01490	COG0019	diaminopimelate decarboxylase activity
J6598_01495	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
J6598_01510	COG1011	Hydrolase
J6598_01530	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
J6598_01535	COG3028	Belongs to the UPF0307 family
J6598_01540	COG0312	modulator of DNA gyrase
J6598_01545	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
J6598_01550	COG5007	Belongs to the BolA IbaG family
J6598_01560	COG2854	intermembrane phospholipid transfer
J6598_01565	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
J6598_01570	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
J6598_01575	COG1127	ABC transporter
J6598_01580	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
J6598_01580	COG0517	IMP dehydrogenase activity
J6598_01585	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
J6598_01590	COG3117	lipopolysaccharide transmembrane transporter activity
J6598_01595	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
J6598_01600	COG1137	ATPase activity
J6598_01615	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
J6598_01620	COG1660	Displays ATPase and GTPase activities
J6598_01625	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
J6598_01630	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
J6598_01635	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
J6598_01645	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
J6598_01650	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
J6598_01655	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
J6598_01660	COG0723	plastoquinol--plastocyanin reductase activity
J6598_01665	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
J6598_01670	COG2857	Cytochrome c1
J6598_01675	COG0625	glutathione transferase activity
J6598_01680	COG2969	positive regulation of protein catabolic process
J6598_01685	COG2823	Periplasmic or secreted lipoprotein
J6598_01690	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
J6598_01695	COG0792	nuclease activity
J6598_01700	COG3107	peptidoglycan biosynthetic process
J6598_01705	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
J6598_01730	COG1987	bacterial-type flagellum assembly
J6598_01755	COG1677	Flagellar hook-basal body complex protein FliE
J6598_01765	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
J6598_01795	COG1261	Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly
J6598_01800	COG1815	bacterial-type flagellum-dependent cell motility
J6598_01815	COG1749	Flagellar hook protein flgE
J6598_01820	COG4787	bacterial-type flagellum-dependent cell motility
J6598_01825	COG4786	Flagellar basal body rod
J6598_01830	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
J6598_01835	COG1706	bacterial-type flagellum-dependent cell motility
J6598_01845	COG4786	Flagellar basal body rod
J6598_01845	COG1256	bacterial-type flagellum assembly
J6598_01850	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
J6598_01860	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
J6598_01865	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
J6598_01890	COG1191	sigma factor activity
J6598_01895	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
J6598_01910	COG1388	LysM domain
J6598_01910	COG0741	lytic transglycosylase activity
J6598_01920	COG2001	Belongs to the MraZ family
J6598_01925	COG0275	rRNA processing
J6598_01930	COG3116	cell division
J6598_01935	COG0768	penicillin binding
J6598_01945	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
J6598_01950	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
J6598_01955	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
J6598_01960	COG0772	Belongs to the SEDS family
J6598_01965	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
J6598_01970	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
J6598_01980	COG0849	cell division
J6598_01985	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
J6598_01990	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
J6598_02000	COG0653	protein targeting
J6598_02005	COG0494	nUDIX hydrolase
J6598_02010	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
J6598_02015	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
J6598_02030	COG1459	type II secretion system
J6598_02035	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
J6598_02060	COG2186	Transcriptional regulator
J6598_02065	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
J6598_02070	COG0508	dehydrogenase complex catalyzes the overall conversion of
J6598_02075	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
J6598_02085	COG0840	transmembrane signaling receptor activity
J6598_02090	COG1752	Esterase of the alpha-beta hydrolase superfamily
J6598_02095	COG1049	propionate catabolic process, 2-methylcitrate cycle
J6598_02100	COG2200	EAL domain
J6598_02110	COG0523	cobalamin synthesis protein
J6598_02115	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
J6598_02130	COG0477	Major facilitator Superfamily
J6598_02145	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
J6598_02150	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
J6598_02175	COG3314	Sporulation integral membrane protein YlbJ
J6598_02225	COG2314	TM2 domain
J6598_02265	COG3314	Sporulation integral membrane protein YlbJ
J6598_02295	COG0165	Argininosuccinate lyase
J6598_02300	COG0137	argininosuccinate synthase activity
J6598_02310	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
J6598_02315	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
J6598_02325	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
J6598_02335	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
J6598_02350	COG0583	DNA-binding transcription factor activity
J6598_02355	COG1380	Effector of murein hydrolase LrgA
J6598_02360	COG1346	cytolysis
J6598_02370	COG4667	esterase of the alpha-beta hydrolase superfamily
J6598_02375	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
J6598_02380	COG1546	Belongs to the CinA family
J6598_02385	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
J6598_02395	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
J6598_02400	COG0527	aspartate kinase activity
J6598_02405	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
J6598_02440	COG1686	Belongs to the peptidase S11 family
J6598_02445	COG0586	Pfam SNARE associated Golgi protein
J6598_02450	COG1253	flavin adenine dinucleotide binding
J6598_02455	COG0252	asparaginase activity
J6598_02475	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
J6598_02475	COG1263	PTS System
J6598_02480	COG0366	Alpha amylase catalytic
J6598_02485	COG0110	maltose O-acetyltransferase activity
J6598_02495	COG0564	pseudouridine synthase activity
J6598_02500	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
J6598_02530	COG2926	Belongs to the UPF0265 family
J6598_02540	COG0561	phosphatase activity
J6598_02550	COG1546	Belongs to the CinA family
J6598_02550	COG1058	Belongs to the CinA family
J6598_02560	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
J6598_02570	COG1522	sequence-specific DNA binding
J6598_02575	COG1368	sulfuric ester hydrolase activity
J6598_02615	COG4221	oxidoreductase activity
J6598_02630	COG1979	alcohol dehydrogenase
J6598_02635	COG1803	Methylglyoxal synthase
J6598_02660	COG1444	tRNA N-acetyltransferase activity
J6598_02670	COG0784	Response regulator, receiver
J6598_02670	COG0835	chemotaxis
J6598_02680	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
J6598_02685	COG2949	membrane
J6598_02690	COG3291	Pkd domain containing protein
J6598_02695	COG0318	PFAM AMP-dependent synthetase and ligase
J6598_02700	COG1441	menaquinone biosynthetic process
J6598_02705	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
J6598_02710	COG0596	Alpha beta hydrolase
J6598_02715	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
J6598_02720	COG1169	isochorismate synthase
J6598_02725	COG1575	Belongs to the MenA family. Type 1 subfamily
J6598_02750	COG0513	Belongs to the DEAD box helicase family
J6598_02755	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
J6598_02760	COG1988	membrane-bound metal-dependent
J6598_02765	COG1671	Belongs to the UPF0178 family
J6598_02785	COG0484	heat shock protein binding
J6598_02795	COG3722	fumarate hydratase activity
J6598_02800	COG0246	Mannitol dehydrogenase
J6598_02805	COG2213	PTS system mannitol-specific
J6598_02805	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
J6598_02810	COG1560	Kdo2-lipid A biosynthetic process
J6598_02815	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
J6598_02815	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
J6598_02820	COG1538	Outer membrane efflux protein
J6598_02825	COG0494	nUDIX hydrolase
J6598_02830	COG3151	Protein conserved in bacteria
J6598_02840	COG3150	esterase
J6598_02865	COG3104	oligopeptide transport
J6598_02895	COG2084	Dehydrogenase
J6598_02900	COG0583	DNA-binding transcription factor activity
J6598_02905	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
J6598_02925	COG0204	Acyl-transferase
J6598_02930	COG1842	Phage shock protein A
J6598_02945	COG2827	Endonuclease containing a URI domain
J6598_02960	COG1573	uracil-dna glycosylase
J6598_02965	COG0697	spore germination
J6598_02970	COG0583	DNA-binding transcription factor activity
J6598_02975	COG1108	ABC-type Mn2 Zn2 transport systems permease components
J6598_02980	COG1121	(ABC) transporter
J6598_02985	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
J6598_03005	COG0739	heme binding
J6598_03015	COG3068	Protein conserved in bacteria
J6598_03040	COG0617	tRNA 3'-terminal CCA addition
J6598_03045	COG1194	a g-specific adenine glycosylase
J6598_03050	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
J6598_03060	COG3111	PFAM Bacterial OB fold (BOF) protein
J6598_03065	COG3240	lipase activity
J6598_03070	COG2885	chlorophyll binding
J6598_03070	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
J6598_03075	COG3706	GGDEF domain
J6598_03080	COG0557	exoribonuclease II activity
J6598_03085	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
J6598_03095	COG2153	protein acetylation
J6598_03100	COG0513	Belongs to the DEAD box helicase family
J6598_03105	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
J6598_03130	COG0735	belongs to the Fur family
J6598_03135	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
J6598_03140	COG0840	transmembrane signaling receptor activity
J6598_03150	COG4166	transmembrane transport
J6598_03160	COG0110	maltose O-acetyltransferase activity
J6598_03170	COG1024	Enoyl-CoA hydratase
J6598_03185	COG4221	oxidoreductase activity
J6598_03190	COG0442	prolyl-tRNA aminoacylation
J6598_03195	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
J6598_03205	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
J6598_03205	COG3008	intermembrane lipid transfer
J6598_03210	COG2995	paraquat-inducible protein a
J6598_03220	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
J6598_03230	COG4251	negative regulation of phosphorylation
J6598_03230	COG5001	Diguanylate cyclase
J6598_03230	COG2203	Gaf domain
J6598_03230	COG3706	GGDEF domain
J6598_03235	COG4776	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction
J6598_03250	COG2771	luxR family
J6598_03260	COG0840	transmembrane signaling receptor activity
J6598_03265	COG0632	four-way junction helicase activity
J6598_03270	COG2255	four-way junction helicase activity
J6598_03280	COG1294	oxidase, subunit
J6598_03285	COG4890	Cyd operon protein YbgT
J6598_03290	COG3790	cyd operon protein YbgE
J6598_03295	COG0824	Thioesterase
J6598_03300	COG0811	peptide transport
J6598_03315	COG0823	Involved in the tonB-independent uptake of proteins
J6598_03320	COG2885	chlorophyll binding
J6598_03325	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
J6598_03390	COG0733	neurotransmitter:sodium symporter activity
J6598_03400	COG0733	neurotransmitter:sodium symporter activity
J6598_03415	COG0561	phosphatase activity
J6598_03465	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
J6598_03470	COG1640	4-alpha-glucanotransferase
J6598_03475	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
J6598_03480	COG0676	glucose-6-phosphate 1-epimerase activity
J6598_03485	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
J6598_03490	COG0840	transmembrane signaling receptor activity
J6598_03495	COG1585	Membrane protein implicated in regulation of membrane protease activity
J6598_03500	COG0330	HflC and HflK could
J6598_03505	COG1648	precorrin-2 dehydrogenase activity
J6598_03505	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
J6598_03510	COG0175	sulfate reduction
J6598_03515	COG2895	sulfate adenylyltransferase (ATP) activity
J6598_03520	COG3273	potassium ion transport
J6598_03520	COG0471	metal ion transport
J6598_03525	COG0529	Catalyzes the synthesis of activated sulfate
J6598_03535	COG0840	transmembrane signaling receptor activity
J6598_03555	COG1136	(ABC) transporter
J6598_03570	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
J6598_03585	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
J6598_03590	COG3437	response regulator, receiver
J6598_03590	COG0784	Response regulator, receiver
J6598_03600	COG2076	Multidrug Resistance protein
J6598_03605	COG2076	Multidrug Resistance protein
J6598_03615	COG0346	lactoylglutathione lyase activity
J6598_03620	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
J6598_03625	COG1643	Atp-dependent helicase
J6598_03635	COG1489	DNA binding
J6598_03640	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
J6598_03645	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
J6598_03655	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
J6598_03660	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
J6598_03665	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
J6598_03670	COG1823	symporter activity
J6598_03700	COG0842	Transport permease protein
J6598_03705	COG1131	(ABC) transporter
J6598_03720	COG0163	prenyltransferase activity
J6598_03725	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
J6598_03730	COG0671	phosphoesterase, PA-phosphatase related
J6598_03735	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
J6598_03740	COG1017	nitric oxide dioxygenase activity
J6598_03740	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
J6598_03745	COG1151	hydroxylamine reductase activity
J6598_03750	COG0783	Belongs to the Dps family
J6598_03755	COG3023	N-Acetylmuramoyl-L-alanine amidase
J6598_03760	COG4807	Protein conserved in bacteria
J6598_03770	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
J6598_03775	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
J6598_03780	COG3956	TIGRFAM MazG family protein
J6598_03785	COG0504	CTP synthase activity
J6598_03790	COG0148	phosphopyruvate hydratase activity
J6598_03805	COG0789	Transcriptional regulator
J6598_03840	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
J6598_03850	COG0488	(ABC) transporter
J6598_03870	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
J6598_03885	COG1794	racemase activity, acting on amino acids and derivatives
J6598_03895	COG2731	YhcH YjgK YiaL family protein
J6598_03905	COG0668	transmembrane transport
J6598_03910	COG1376	ErfK ybiS ycfS ynhG family protein
J6598_03920	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
J6598_03925	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
J6598_03930	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
J6598_03940	COG0585	pseudouridine synthase activity
J6598_03945	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
J6598_03950	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
J6598_03955	COG1238	metal cluster binding
J6598_03970	COG1902	pentaerythritol trinitrate reductase activity
J6598_03980	COG2852	Protein conserved in bacteria
J6598_03990	COG2957	Belongs to the agmatine deiminase family
J6598_03995	COG0154	amidase activity
J6598_04030	COG0513	Belongs to the DEAD box helicase family
J6598_04035	COG2199	diguanylate cyclase activity
J6598_04035	COG2203	Gaf domain
J6598_04045	COG1912	Pfam S-adenosyl-l-methionine hydroxide adenosyltransferase
J6598_04090	COG2816	NAD+ diphosphatase activity
J6598_04125	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
J6598_04140	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
J6598_04145	COG4991	sh3 domain protein
J6598_04155	COG2816	NAD+ diphosphatase activity
J6598_04160	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
J6598_04165	COG1940	carbohydrate kinase activity
J6598_04170	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
J6598_04175	COG0126	phosphoglycerate kinase activity
J6598_04185	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
J6598_04230	COG0354	folic acid binding
J6598_04245	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
J6598_04250	COG1595	DNA-templated transcription, initiation
J6598_04255	COG3073	An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E
J6598_04260	COG3026	antisigma factor binding
J6598_04270	COG0481	GTPase activity
J6598_04275	COG0681	Belongs to the peptidase S26 family
J6598_04290	COG1381	Involved in DNA repair and RecF pathway recombination
J6598_04295	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
J6598_04305	COG2350	Protein conserved in bacteria
J6598_04310	COG2917	probably involved in intracellular septation
J6598_04315	COG0076	glutamate decarboxylase activity
J6598_04320	COG1272	protein, Hemolysin III
J6598_04325	COG2985	domain, Protein
J6598_04325	COG0569	domain protein
J6598_04385	COG3076	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome
J6598_04405	COG1858	cytochrome C peroxidase
J6598_04415	COG2313	pseudouridylate synthase activity
J6598_04420	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
J6598_04460	COG1765	OsmC-like protein
J6598_04475	COG3954	Phosphoribulokinase
J6598_04480	COG3089	Belongs to the UPF0270 family
J6598_04485	COG5001	Diguanylate cyclase
J6598_04485	COG2203	Gaf domain
J6598_04485	COG4251	negative regulation of phosphorylation
J6598_04485	COG3706	GGDEF domain
J6598_04490	COG0429	hydrolase of the alpha beta-hydrolase fold
J6598_04495	COG0835	chemotaxis
J6598_04495	COG0784	Response regulator, receiver
J6598_04505	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
J6598_04510	COG1047	Peptidyl-prolyl cis-trans
J6598_04515	COG2900	Belongs to the SlyX family
J6598_04525	COG0545	Peptidyl-prolyl cis-trans isomerase
J6598_04530	COG2204	response regulator
J6598_04550	COG0737	Belongs to the 5'-nucleotidase family
J6598_04565	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
J6598_04575	COG3340	Belongs to the peptidase S51 family
J6598_04590	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
J6598_04600	COG3721	Heme iron utilization protein
J6598_04605	COG0748	coenzyme F420 binding
J6598_04630	COG2814	Major facilitator Superfamily
J6598_04640	COG3655	Transcriptional regulator
J6598_04650	COG0784	Response regulator, receiver
J6598_04650	COG2205	protein histidine kinase activity
J6598_04650	COG5002	protein histidine kinase activity
J6598_04675	COG3397	chitin binding
J6598_04715	COG0784	Response regulator, receiver
J6598_04715	COG0835	chemotaxis
J6598_04720	COG2755	lipolytic protein G-D-S-L family
J6598_04725	COG4181	ATPase activity
J6598_04730	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
J6598_04735	COG1090	epimerase
J6598_04740	COG2200	EAL domain
J6598_04745	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
J6598_04750	COG0220	tRNA (guanine-N7-)-methyltransferase activity
J6598_04755	COG3171	Protein conserved in bacteria
J6598_04760	COG2066	Belongs to the glutaminase family
J6598_04765	COG2897	thiosulfate sulfurtransferase activity
J6598_04780	COG0521	Mo-molybdopterin cofactor biosynthetic process
J6598_04790	COG2966	Psort location CytoplasmicMembrane, score
J6598_04795	COG3610	response to peptide
J6598_04810	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
J6598_04815	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
J6598_04820	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
J6598_04835	COG0786	glutamate:sodium symporter activity
J6598_04840	COG0252	asparaginase activity
J6598_04845	COG3139	Protein of unknown function (DUF1315)
J6598_04865	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
J6598_04870	COG0321	lipoyl(octanoyl) transferase activity
J6598_04875	COG2921	Belongs to the UPF0250 family
J6598_04880	COG1686	Belongs to the peptidase S11 family
J6598_04885	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
J6598_04890	COG2951	lytic endotransglycosylase activity
J6598_04895	COG0772	Belongs to the SEDS family
J6598_04900	COG0768	penicillin binding
J6598_04905	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
J6598_04910	COG0799	negative regulation of ribosome biogenesis
J6598_04915	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
J6598_04930	COG0495	leucyl-tRNA aminoacylation
J6598_04935	COG2888	peptidyl-tyrosine sulfation
J6598_04950	COG0716	FMN binding
J6598_04955	COG4974	Belongs to the 'phage' integrase family
J6598_04965	COG1970	mechanosensitive ion channel activity
J6598_04975	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
J6598_04980	COG0789	Transcriptional regulator
J6598_04985	COG0815	Transfers the fatty acyl group on membrane lipoproteins
J6598_04990	COG4535	Mg2 and Co2 transporter CorC
J6598_04995	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
J6598_05000	COG1702	phosphate starvation-inducible protein PhoH
J6598_05005	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
J6598_05010	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
J6598_05015	COG1335	isochorismatase
J6598_05025	COG3706	GGDEF domain
J6598_05030	COG0583	DNA-binding transcription factor activity
J6598_05055	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
J6598_05065	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
J6598_05075	COG0516	GMP reductase activity
J6598_05095	COG0642	Histidine kinase
J6598_05110	COG4221	oxidoreductase activity
J6598_05135	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
J6598_05150	COG3214	Protein conserved in bacteria
J6598_05160	COG2195	Cleaves the N-terminal amino acid of tripeptides
J6598_05165	COG0700	Nucleoside recognition
J6598_05170	COG3366	ferrous iron transmembrane transporter activity
J6598_05175	COG3080	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
J6598_05180	COG3029	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
J6598_05185	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
J6598_05190	COG1053	succinate dehydrogenase
J6598_05200	COG0584	glycerophosphoryl diester phosphodiesterase
J6598_05205	COG1511	domain protein
J6598_05205	COG3264	Mechanosensitive ion channel
J6598_05215	COG0739	heme binding
J6598_05225	COG0583	DNA-binding transcription factor activity
J6598_05245	COG0583	DNA-binding transcription factor activity
J6598_05250	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
J6598_05280	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
J6598_05285	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
J6598_05295	COG0338	D12 class N6 adenine-specific DNA methyltransferase
J6598_05300	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
J6598_05310	COG0180	Tryptophanyl-tRNA synthetase
J6598_05320	COG0512	Glutamine amidotransferase of anthranilate synthase
J6598_05325	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
J6598_05335	COG1012	belongs to the aldehyde dehydrogenase family
J6598_05350	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
J6598_05360	COG0674	pyruvate-flavodoxin oxidoreductase activity
J6598_05360	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
J6598_05360	COG1013	pyruvate-flavodoxin oxidoreductase activity
J6598_05360	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
J6598_05365	COG0366	Alpha amylase catalytic
J6598_05375	COG3097	Belongs to the UPF0267 family
J6598_05385	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
J6598_05395	COG0471	metal ion transport
J6598_05395	COG0490	domain, Protein
J6598_05440	COG0012	GTP binding
J6598_05445	COG0193	aminoacyl-tRNA hydrolase activity
J6598_05450	COG0737	Belongs to the 5'-nucleotidase family
J6598_05455	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
J6598_05465	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
J6598_05470	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
J6598_05475	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
J6598_05480	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
J6598_05485	COG2890	protein-(glutamine-N5) methyltransferase activity
J6598_05495	COG2912	Transglutaminase-like superfamily
J6598_05500	COG2877	3-deoxy-8-phosphooctulonate synthase activity
J6598_05515	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
J6598_05525	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
J6598_05525	COG3408	Glycogen debranching enzyme
J6598_05535	COG1881	PFAM PEBP family protein
J6598_05540	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
J6598_05555	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
J6598_05565	COG0583	DNA-binding transcription factor activity
J6598_05570	COG1028	Short-chain dehydrogenase reductase Sdr
J6598_05575	COG0616	signal peptide processing
J6598_05580	COG2211	Major facilitator Superfamily
J6598_05590	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
J6598_05600	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
J6598_05605	COG0826	peptidase U32
J6598_05630	COG3724	N-succinylarginine dihydrolase activity
J6598_05640	COG3385	transposase activity
J6598_05660	COG0840	transmembrane signaling receptor activity
J6598_05670	COG2971	BadF BadG BcrA BcrD
J6598_05680	COG4608	Belongs to the ABC transporter superfamily
J6598_05685	COG0444	Belongs to the ABC transporter superfamily
J6598_05690	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
J6598_05695	COG0601	transmembrane transport
J6598_05705	COG0784	Response regulator, receiver
J6598_05705	COG2205	protein histidine kinase activity
J6598_05735	COG3220	belongs to the UPF0276 family
J6598_05765	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
J6598_05770	COG1289	transmembrane transporter activity
J6598_05775	COG0303	'Molybdopterin
J6598_05780	COG0746	molybdenum cofactor guanylyltransferase activity
J6598_05790	COG4662	Binding-protein-dependent transport system inner membrane component
J6598_05800	COG2204	response regulator
J6598_05805	COG3852	Histidine kinase
J6598_05815	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
J6598_05850	COG3383	formate dehydrogenase (NAD+) activity
J6598_05850	COG3383	formate dehydrogenase (NAD+) activity
J6598_05855	COG0437	4 iron, 4 sulfur cluster binding
J6598_05875	COG0281	malic enzyme
J6598_05895	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
J6598_05925	COG0837	glucose binding
J6598_05930	COG1737	Transcriptional regulator
J6598_05935	COG0469	pyruvate kinase activity
J6598_05960	COG1677	Flagellar hook-basal body complex protein FliE
J6598_05970	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
J6598_06025	COG1684	flagellar biosynthetic protein fliR
J6598_06035	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
J6598_06060	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
J6598_06065	COG0784	Response regulator, receiver
J6598_06065	COG0643	Histidine kinase
J6598_06065	COG2198	Histidine kinase
J6598_06075	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
J6598_06080	COG1360	Flagellar Motor Protein
J6598_06085	COG1192	Involved in chromosome partitioning
J6598_06095	COG0835	chemotaxis
J6598_06110	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
J6598_06115	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
J6598_06120	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
J6598_06125	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
J6598_06130	COG1138	Cytochrome C-type biogenesis protein
J6598_06135	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
J6598_06140	COG3088	subunit of a heme lyase
J6598_06140	COG4235	cytochrome complex assembly
J6598_06150	COG2853	Lipoprotein
J6598_06160	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
J6598_06165	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
J6598_06175	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
J6598_06180	COG1882	Formate acetyltransferase
J6598_06185	COG0251	oxidation-reduction process
J6598_06190	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
J6598_06190	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
J6598_06220	COG0259	pyridoxamine-phosphate oxidase activity
J6598_06225	COG0625	glutathione transferase activity
J6598_06245	COG2850	peptidyl-arginine hydroxylation
J6598_06250	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
J6598_06255	COG2915	High frequency lysogenization protein hflD homolog
J6598_06260	COG0482	sulfurtransferase activity
J6598_06270	COG1187	pseudouridine synthase activity
J6598_06275	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
J6598_06275	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
J6598_06275	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
J6598_06280	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
J6598_06285	COG2271	Major facilitator Superfamily
J6598_06290	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
J6598_06290	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
J6598_06290	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
J6598_06330	COG1609	Transcriptional regulator
J6598_06335	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
J6598_06335	COG1263	PTS System
J6598_06340	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
J6598_06365	COG4792	protein secretion
J6598_06370	COG4791	protein targeting
J6598_06375	COG4794	Type iii secretion
J6598_06380	COG4790	Type iii secretion
J6598_06450	COG0457	Tetratricopeptide repeat
J6598_06540	COG1317	bacterial-type flagellum organization
J6598_06545	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
J6598_06555	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
J6598_06560	COG1960	acyl-CoA dehydrogenase activity
J6598_06570	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
J6598_06585	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
J6598_06590	COG2867	negative regulation of translational initiation
J6598_06595	COG2914	Belongs to the UPF0125 (RnfH) family
J6598_06600	COG1473	amidohydrolase
J6598_06605	COG1960	acyl-CoA dehydrogenase activity
J6598_06610	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
J6598_06615	COG0121	glutamine amidotransferase
J6598_06645	COG2197	response regulator
J6598_06650	COG3850	Histidine kinase
J6598_06655	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
J6598_06660	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
J6598_06670	COG0243	molybdopterin cofactor binding
J6598_06675	COG0437	4 iron, 4 sulfur cluster binding
J6598_06680	COG0348	domain, Protein
J6598_06690	COG3005	denitrification pathway
J6598_06695	COG0521	Mo-molybdopterin cofactor biosynthetic process
J6598_06700	COG0315	cyclic pyranopterin monophosphate synthase activity
J6598_06705	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
J6598_06710	COG0314	molybdopterin synthase activity
J6598_06725	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
J6598_06730	COG2267	carboxylic ester hydrolase activity
J6598_06745	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
J6598_06755	COG0302	gtp cyclohydrolase
J6598_06760	COG0840	transmembrane signaling receptor activity
J6598_06765	COG0840	transmembrane signaling receptor activity
J6598_06770	COG2759	Belongs to the formate--tetrahydrofolate ligase family
J6598_06780	COG0583	DNA-binding transcription factor activity
J6598_06785	COG2353	YceI-like domain
J6598_06795	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
J6598_06810	COG2195	Cleaves the N-terminal amino acid of tripeptides
J6598_06815	COG1166	arginine decarboxylase activity
J6598_06835	COG0814	amino acid
J6598_06845	COG3681	Belongs to the UPF0597 family
J6598_06850	COG2964	Protein conserved in bacteria
J6598_06860	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
J6598_06865	COG1288	antiporter activity
J6598_06870	COG0436	Aminotransferase
J6598_06880	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
J6598_06885	COG0739	heme binding
J6598_06885	COG0741	lytic transglycosylase activity
J6598_06885	COG1196	nuclear chromosome segregation
J6598_06900	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
J6598_06910	COG0788	formyltetrahydrofolate deformylase activity
J6598_06915	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
J6598_06925	COG3118	belongs to the thioredoxin family
J6598_06935	COG0791	NLP P60 protein
J6598_06940	COG3129	Specifically methylates the adenine in position 1618 of 23S rRNA
J6598_06950	COG0471	metal ion transport
J6598_06960	COG1376	ErfK ybiS ycfS ynhG family protein
J6598_06960	COG1388	LysM domain
J6598_06975	COG1846	Transcriptional regulator
J6598_06975	COG1940	carbohydrate kinase activity
J6598_06980	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
J6598_06985	COG0363	glucosamine-6-phosphate deaminase activity
J6598_06990	COG1263	PTS System
J6598_06990	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
J6598_06990	COG2190	(PTS) system
J6598_07000	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
J6598_07005	COG0735	belongs to the Fur family
J6598_07015	COG0716	FMN binding
J6598_07030	COG0596	Alpha beta hydrolase
J6598_07035	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
J6598_07040	COG0033	Phosphoglucomutase
J6598_07045	COG2951	lytic endotransglycosylase activity
J6598_07050	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
J6598_07055	COG4136	ATPase activity
J6598_07065	COG4134	Bacterial extracellular solute-binding protein
J6598_07075	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
J6598_07085	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
J6598_07095	COG0729	surface antigen
J6598_07100	COG2911	Protein conserved in bacteria
J6598_07120	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
J6598_07130	COG0741	lytic transglycosylase activity
J6598_07135	COG1609	Transcriptional regulator
J6598_07140	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
J6598_07145	COG4771	TonB-dependent receptor
J6598_07150	COG1169	isochorismate synthase
J6598_07155	COG1021	2,3-dihydroxybenzoate-AMP ligase
J6598_07160	COG3433	isochorismatase activity
J6598_07160	COG1535	isochorismatase
J6598_07165	COG1028	Short-chain dehydrogenase reductase Sdr
J6598_07170	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
J6598_07170	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
J6598_07195	COG1278	Cold shock
J6598_07220	COG0747	negative chemotaxis
J6598_07225	COG1349	DNA-binding transcription factor activity
J6598_07230	COG1882	Formate acetyltransferase
J6598_07235	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
J6598_07240	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
J6598_07250	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
J6598_07255	COG1187	pseudouridine synthase activity
J6598_07265	COG4166	transmembrane transport
J6598_07270	COG0622	Phosphoesterase
J6598_07285	COG1261	Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly
J6598_07290	COG0835	chemotaxis
J6598_07290	COG0784	Response regulator, receiver
J6598_07295	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
J6598_07300	COG1815	bacterial-type flagellum-dependent cell motility
J6598_07310	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
J6598_07320	COG4787	bacterial-type flagellum-dependent cell motility
J6598_07330	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
J6598_07335	COG1706	bacterial-type flagellum-dependent cell motility
J6598_07350	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
J6598_07355	COG2239	Acts as a magnesium transporter
J6598_07365	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
J6598_07370	COG2716	regulation of RNA biosynthetic process
J6598_07395	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
J6598_07400	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
J6598_07405	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
J6598_07410	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
J6598_07430	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
J6598_07445	COG0590	tRNA wobble adenosine to inosine editing
J6598_07450	COG0573	inorganic phosphate transmembrane transporter activity
J6598_07455	COG0581	inorganic phosphate transmembrane transporter activity
J6598_07460	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
J6598_07465	COG0704	Plays a role in the regulation of phosphate uptake
J6598_07470	COG1253	flavin adenine dinucleotide binding
J6598_07485	COG0531	amino acid
J6598_07500	COG1126	abc transporter atp-binding protein
J6598_07505	COG0765	amino acid transport
J6598_07510	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
J6598_07520	COG2271	Major facilitator Superfamily
J6598_07530	COG2197	response regulator
J6598_07535	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
J6598_07555	COG1785	Belongs to the alkaline phosphatase family
J6598_07560	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
J6598_07565	COG0123	including yeast histone deacetylase and acetoin utilization protein
J6598_07575	COG1199	ATP-dependent helicase activity
J6598_07585	COG0287	Prephenate dehydrogenase
J6598_07585	COG1605	Chorismate mutase
J6598_07590	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
J6598_07600	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
J6598_07605	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
J6598_07640	COG0537	adenosine 5'-monophosphoramidase activity
J6598_07655	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
J6598_07675	COG1301	dicarboxylic acid transport
J6598_07680	COG0840	transmembrane signaling receptor activity
J6598_07695	COG2354	Protein conserved in bacteria
J6598_07705	COG2233	PERMEase
J6598_07710	COG3150	esterase
J6598_07715	COG1252	NADH dehydrogenase
J6598_07725	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
J6598_07735	COG0446	pyridine nucleotide-disulphide oxidoreductase
J6598_07745	COG2373	Large extracellular alpha-helical protein
J6598_07750	COG4953	penicillin-binding protein 1C
J6598_07760	COG0301	tRNA thio-modification
J6598_07760	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
J6598_07775	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
J6598_07780	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
J6598_07830	COG4310	Domain of unknown function (DUF2172)
J6598_07850	COG2089	acid synthase
J6598_07860	COG1083	cytidylyl-transferase
J6598_07875	COG1028	Short-chain dehydrogenase reductase Sdr
J6598_07880	COG0318	PFAM AMP-dependent synthetase and ligase
J6598_07895	COG1215	transferase activity, transferring glycosyl groups
J6598_07900	COG1442	glycosyl transferase family 8
J6598_07910	COG1216	Glycosyl transferase, family 2
J6598_07910	COG1442	glycosyl transferase family 8
J6598_07920	COG1215	transferase activity, transferring glycosyl groups
J6598_07950	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
J6598_07975	COG0529	Catalyzes the synthesis of activated sulfate
J6598_07985	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
J6598_07990	COG3848	Pyruvate phosphate dikinase
J6598_07990	COG0574	Belongs to the PEP-utilizing enzyme family
J6598_07995	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
J6598_08000	COG1213	nucleotidyl transferase
J6598_08010	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
J6598_08030	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
J6598_08035	COG1086	Polysaccharide biosynthesis protein
J6598_08040	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
J6598_08050	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
J6598_08065	COG0483	inositol monophosphate 1-phosphatase activity
J6598_08075	COG0625	glutathione transferase activity
J6598_08080	COG2814	Major facilitator Superfamily
J6598_08100	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
J6598_08105	COG0243	molybdopterin cofactor binding
J6598_08125	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
J6598_08130	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
J6598_08140	COG0404	The glycine cleavage system catalyzes the degradation of glycine
J6598_08145	COG0509	glycine decarboxylation via glycine cleavage system
J6598_08150	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
J6598_08150	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
J6598_08155	COG0840	transmembrane signaling receptor activity
J6598_08185	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
J6598_08190	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
J6598_08190	COG0574	Belongs to the PEP-utilizing enzyme family
J6598_08205	COG1464	Belongs to the NlpA lipoprotein family
J6598_08210	COG3083	sulfuric ester hydrolase activity
J6598_08215	COG3082	Protein of unknown function (DUF1414)
J6598_08220	COG3081	Nucleoid-associated protein
J6598_08230	COG1175	transmembrane transport
J6598_08235	COG3833	ABC-type maltose transport systems, permease component
J6598_08240	COG3842	ATPase activity
J6598_08270	COG4783	chaperone-mediated protein folding
J6598_08280	COG1393	Belongs to the ArsC family
J6598_08290	COG3124	Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP
J6598_08300	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
J6598_08305	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
J6598_08310	COG2431	L-lysine efflux transmembrane transporter activity
J6598_08320	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
J6598_08330	COG4160	amino acid transport
J6598_08335	COG0564	pseudouridine synthase activity
J6598_08350	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
J6598_08360	COG0625	glutathione transferase activity
J6598_08365	COG0740	serine-type endopeptidase activity
J6598_08375	COG0367	asparagine synthase
J6598_08385	COG4651	solute:proton antiporter activity
J6598_08385	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
J6598_08390	COG0647	UMP catabolic process
J6598_08405	COG1902	pentaerythritol trinitrate reductase activity
J6598_08410	COG1253	flavin adenine dinucleotide binding
J6598_08420	COG0247	lactate metabolic process
J6598_08420	COG0277	FAD linked oxidase domain protein
J6598_08430	COG2050	protein possibly involved in aromatic compounds catabolism
J6598_08460	COG2199	diguanylate cyclase activity
J6598_08460	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
J6598_08475	COG1007	ATP synthesis coupled electron transport
J6598_08480	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
J6598_08490	COG0713	ATP synthesis coupled electron transport
J6598_08495	COG0839	Belongs to the complex I subunit 6 family
J6598_08500	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
J6598_08505	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
J6598_08510	COG1034	ATP synthesis coupled electron transport
J6598_08525	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
J6598_08525	COG0649	NAD binding
J6598_08530	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
J6598_08535	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
J6598_08555	COG1770	oligopeptidase
J6598_08560	COG4771	TonB-dependent receptor
J6598_08565	COG1360	Flagellar Motor Protein
J6598_08570	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
J6598_08580	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
J6598_08610	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
J6598_08620	COG3770	Murein endopeptidase that cleaves the D-alanyl-meso-2,6- diamino-pimelyl amide bond that connects peptidoglycan strands. Likely plays a role in the removal of murein from the sacculus
J6598_08625	COG4597	amino acid ABC transporter
J6598_08630	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
J6598_08635	COG0765	amino acid transport
J6598_08640	COG1126	abc transporter atp-binding protein
J6598_08650	COG0724	RNA recognition motif
J6598_08655	COG4989	oxidoreductase activity
J6598_08680	COG3437	response regulator, receiver
J6598_08685	COG0583	DNA-binding transcription factor activity
J6598_08690	COG5001	Diguanylate cyclase
J6598_08690	COG3300	MHYT domain
J6598_08695	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
J6598_08715	COG2814	Major facilitator Superfamily
J6598_08730	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
J6598_08735	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
J6598_08740	COG0539	negative regulation of cytoplasmic translation
J6598_08745	COG0776	regulation of translation
J6598_08755	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
J6598_08760	COG0284	orotidine-5'-phosphate decarboxylase activity
J6598_08775	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
J6598_08780	COG0602	queuosine metabolic process
J6598_08785	COG3530	Putative quorum-sensing-regulated virulence factor
J6598_08790	COG2096	Adenosyltransferase
J6598_08795	COG2916	Histone family protein nucleoid-structuring protein H-NS
J6598_08800	COG1757	Na H antiporter
J6598_08805	COG1435	thymidine kinase activity
J6598_08825	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
J6598_08830	COG0326	Molecular chaperone. Has ATPase activity
J6598_08835	COG4172	Belongs to the ABC transporter superfamily
J6598_08840	COG4172	Belongs to the ABC transporter superfamily
J6598_08850	COG4168	peptide transport system, permease
J6598_08860	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
J6598_08865	COG1842	Phage shock protein A
J6598_08880	COG3106	COG3106 Predicted ATPase
J6598_08885	COG3768	UPF0283 membrane protein
J6598_08895	COG2154	pterin-4-alpha-carbinolamine dehydratase
J6598_08915	COG2199	diguanylate cyclase activity
J6598_08920	COG2885	chlorophyll binding
J6598_08925	COG0861	Integral membrane protein TerC family
J6598_08960	COG2910	NAD(P)H-binding
J6598_08965	COG0583	DNA-binding transcription factor activity
J6598_08970	COG0583	DNA-binding transcription factor activity
J6598_08975	COG2271	Major facilitator Superfamily
J6598_08985	COG1335	isochorismatase
J6598_08995	COG0583	DNA-binding transcription factor activity
J6598_09000	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
J6598_09010	COG0583	DNA-binding transcription factor activity
J6598_09015	COG2723	6-phospho-beta-galactosidase activity
J6598_09020	COG1944	ATP diphosphatase activity
J6598_09025	COG2116	formate transmembrane transporter activity
J6598_09030	COG1882	Formate acetyltransferase
J6598_09035	COG2983	Belongs to the UPF0260 family
J6598_09050	COG0058	SHG alpha-glucan phosphorylase activity
J6598_09055	COG0471	metal ion transport
J6598_09060	COG3118	belongs to the thioredoxin family
J6598_09070	COG1132	(ABC) transporter
J6598_09075	COG1132	(ABC) transporter
J6598_09085	COG2501	S4 domain
J6598_09100	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
J6598_09145	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
J6598_09150	COG1053	succinate dehydrogenase
J6598_09160	COG0567	Dehydrogenase, E1 component
J6598_09165	COG0508	dehydrogenase complex catalyzes the overall conversion of
J6598_09170	COG0045	succinate-CoA ligase (ADP-forming) activity
J6598_09185	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
J6598_09195	COG3842	ATPase activity
J6598_09200	COG1840	ABC-type Fe3 transport system, periplasmic component
J6598_09210	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
J6598_09215	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
J6598_09220	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
J6598_09235	COG4235	cytochrome complex assembly
J6598_09235	COG3088	subunit of a heme lyase
J6598_09245	COG1138	Cytochrome C-type biogenesis protein
J6598_09250	COG3301	Polysulphide reductase, NrfD
J6598_09255	COG0437	4 iron, 4 sulfur cluster binding
J6598_09260	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
J6598_09275	COG0247	lactate metabolic process
J6598_09280	COG3075	Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses fumarate or nitrate as electron acceptor
J6598_09285	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
J6598_09290	COG3012	SEC-C Motif Domain Protein
J6598_09295	COG0840	transmembrane signaling receptor activity
J6598_09300	COG1846	Transcriptional regulator
J6598_09300	COG1940	carbohydrate kinase activity
J6598_09305	COG3148	PFAM DTW domain containing protein
J6598_09310	COG0730	response to heat
J6598_09315	COG0583	DNA-binding transcription factor activity
J6598_09330	COG3593	DNA synthesis involved in DNA repair
J6598_09380	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
J6598_09385	COG1011	Hydrolase
J6598_09400	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
J6598_09405	COG2832	Protein of unknown function (DUF454)
J6598_09410	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
J6598_09415	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
J6598_09420	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
J6598_09425	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
J6598_09440	COG1560	Kdo2-lipid A biosynthetic process
J6598_09445	COG1560	Kdo2-lipid A biosynthetic process
J6598_09460	COG2203	Gaf domain
J6598_09460	COG2199	diguanylate cyclase activity
J6598_09470	COG0417	DNA replication proofreading
J6598_09485	COG1451	nucleotide metabolic process
J6598_09500	COG3069	C4-dicarboxylate transmembrane transporter activity
J6598_09515	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
J6598_09515	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
J6598_09520	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
J6598_09525	COG0569	domain protein
J6598_09525	COG2985	domain, Protein
J6598_09535	COG0556	nucleotide-excision repair
J6598_09545	COG0586	Pfam SNARE associated Golgi protein
J6598_09550	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
J6598_09555	COG3067	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
J6598_09570	COG4681	YaeQ
J6598_09580	COG2932	Transcriptional regulator
J6598_09695	COG0640	Transcriptional regulator
J6598_09705	COG4373	Mu-like prophage FluMu protein gp28
J6598_09710	COG4383	Mu-like prophage protein gp29
J6598_09750	COG4388	Caudovirus prohead serine protease
J6598_09755	COG4397	Mu-like prophage major head subunit gpT
J6598_09860	COG3829	transcription factor binding
J6598_09900	COG0307	riboflavin synthase, alpha
J6598_09910	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
J6598_09915	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
J6598_09920	COG0697	spore germination
J6598_09925	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
J6598_09965	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
J6598_09970	COG3099	Belongs to the UPF0263 family
J6598_09975	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
J6598_09980	COG2894	cell division
J6598_09985	COG0850	regulation of cytokinetic process
J6598_09990	COG3100	YcgL domain-containing protein
J6598_09995	COG1760	l-serine dehydratase
J6598_10000	COG1760	l-serine dehydratase
J6598_10005	COG3123	guanosine phosphorylase activity
J6598_10015	COG0205	6-phosphofructokinase activity
J6598_10025	COG1434	Gram-negative-bacterium-type cell wall biogenesis
J6598_10030	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
J6598_10040	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
J6598_10045	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
J6598_10050	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
J6598_10065	COG0242	peptide deformylase activity
J6598_10095	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
J6598_10100	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
J6598_10105	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
J6598_10115	COG0549	Belongs to the carbamate kinase family
J6598_10120	COG0697	spore germination
J6598_10130	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
J6598_10130	COG3608	succinylglutamate desuccinylase aspartoacylase
J6598_10135	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
J6598_10140	COG2068	MobA-Related Protein
J6598_10145	COG0493	'glutamate synthase
J6598_10145	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
J6598_10150	COG0402	S-adenosylhomocysteine deaminase activity
J6598_10155	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
J6598_10160	COG2080	2 iron, 2 sulfur cluster binding
J6598_10160	COG1529	Aldehyde oxidase and xanthine dehydrogenase
J6598_10165	COG2233	PERMEase
J6598_10170	COG0402	S-adenosylhomocysteine deaminase activity
J6598_10175	COG2252	PERMEase
J6598_10180	COG1529	Aldehyde oxidase and xanthine dehydrogenase
J6598_10185	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
J6598_10190	COG2080	2 iron, 2 sulfur cluster binding
J6598_10195	COG3134	Outer membrane lipoprotein
J6598_10205	COG1288	antiporter activity
J6598_10210	COG0318	PFAM AMP-dependent synthetase and ligase
J6598_10215	COG2199	diguanylate cyclase activity
J6598_10230	COG0107	imidazoleglycerol-phosphate synthase activity
J6598_10235	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
J6598_10240	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
J6598_10245	COG0131	Imidazoleglycerol-phosphate dehydratase
J6598_10245	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
J6598_10250	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
J6598_10255	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
J6598_10260	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
J6598_10270	COG1199	ATP-dependent helicase activity
J6598_10275	COG1214	PFAM Peptidase M22, glycoprotease
J6598_10285	COG2267	carboxylic ester hydrolase activity
J6598_10290	COG0318	PFAM AMP-dependent synthetase and ligase
J6598_10300	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
J6598_10305	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
J6598_10310	COG0709	Synthesizes selenophosphate from selenide and ATP
J6598_10320	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
J6598_10325	COG0840	transmembrane signaling receptor activity
J6598_10330	COG1254	Belongs to the acylphosphatase family
J6598_10340	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
J6598_10340	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
J6598_10345	COG0489	protein tyrosine kinase activity
J6598_10350	COG0572	uridine kinase
J6598_10355	COG0717	Belongs to the dCTP deaminase family
J6598_10360	COG0306	phosphate transporter
J6598_10365	COG3313	Fe-S protein
J6598_10370	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
J6598_10380	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
J6598_10385	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
J6598_10390	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
J6598_10400	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
J6598_10410	COG0366	Alpha amylase catalytic
J6598_10430	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
J6598_10435	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
J6598_10440	COG0291	Belongs to the bacterial ribosomal protein bL35 family
J6598_10445	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
J6598_10450	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
J6598_10455	COG0072	phenylalanine-tRNA ligase activity
J6598_10455	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
J6598_10460	COG0776	regulation of translation
J6598_10465	COG0784	Response regulator, receiver
J6598_10465	COG2205	protein histidine kinase activity
J6598_10490	COG3300	MHYT domain
J6598_10490	COG5001	Diguanylate cyclase
J6598_10495	COG1609	Transcriptional regulator
J6598_10500	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
J6598_10505	COG1879	ABC-type sugar transport system periplasmic component
J6598_10510	COG1172	Belongs to the binding-protein-dependent transport system permease family
J6598_10515	COG1129	ABC transporter
J6598_10520	COG1869	D-ribose catabolic process
J6598_10525	COG0625	glutathione transferase activity
J6598_10540	COG1177	transmembrane transport
J6598_10565	COG0037	tRNA processing
J6598_10570	COG0589	response to stress
J6598_10575	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
J6598_10590	COG2217	Heavy metal translocating P-type atpase
J6598_10600	COG2010	Cytochrome c
J6598_10615	COG3278	Belongs to the heme-copper respiratory oxidase family
J6598_10625	COG1956	GAF domain-containing protein
J6598_10630	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
J6598_10640	COG0308	aminopeptidase N
J6598_10650	COG2902	Dehydrogenase
J6598_10655	COG0167	dihydroorotate dehydrogenase activity
J6598_10670	COG0254	rRNA binding
J6598_10675	COG0257	Belongs to the bacterial ribosomal protein bL36 family
J6598_10680	COG0116	Belongs to the methyltransferase superfamily
J6598_10680	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
J6598_10690	COG0488	(ABC) transporter
J6598_10700	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
J6598_10705	COG1067	ATP-dependent peptidase activity
J6598_10735	COG3141	response to X-ray
J6598_10740	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
J6598_10745	COG4221	oxidoreductase activity
J6598_10790	COG0372	Belongs to the citrate synthase family
J6598_10795	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
J6598_10805	COG2995	paraquat-inducible protein a
J6598_10810	COG3008	intermembrane lipid transfer
J6598_10815	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
J6598_10815	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
J6598_10830	COG0084	hydrolase, TatD family'
J6598_10835	COG0470	DNA polymerase III
J6598_10840	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
J6598_10845	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
J6598_10850	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
J6598_10855	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
J6598_10860	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
J6598_10865	COG1028	Short-chain dehydrogenase reductase Sdr
J6598_10875	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
J6598_10880	COG0416	fatty acid biosynthetic process
J6598_10885	COG0333	Belongs to the bacterial ribosomal protein bL32 family
J6598_10890	COG1399	metal-binding, possibly nucleic acid-binding protein
J6598_10895	COG0424	maF-like protein
J6598_10910	COG1530	ribonuclease E activity
J6598_10915	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
J6598_10915	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
J6598_10915	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
J6598_10920	COG1105	Belongs to the carbohydrate kinase PfkB family
J6598_10925	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
J6598_10925	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
J6598_10930	COG1609	Transcriptional regulator
J6598_10935	COG0814	amino acid
J6598_10950	COG3788	relative of glutathione S-transferase, MAPEG superfamily
J6598_10960	COG0513	Belongs to the DEAD box helicase family
J6598_10970	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
J6598_10975	COG2890	protein-(glutamine-N5) methyltransferase activity
J6598_10980	COG2840	Smr protein MutS2
J6598_10985	COG3706	GGDEF domain
J6598_10990	COG0406	alpha-ribazole phosphatase activity
J6598_11005	COG2824	Alkylphosphonate utilization operon protein PhnA
J6598_11020	COG0494	nUDIX hydrolase
J6598_11025	COG0814	amino acid
J6598_11030	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
J6598_11035	COG0514	ATP-dependent DNA helicase (RecQ)
J6598_11040	COG2766	serine protein kinase
J6598_11045	COG2718	Belongs to the UPF0229 family
J6598_11050	COG2719	SpoVR family
J6598_11055	COG1250	3-hydroxyacyl-CoA dehydrogenase
J6598_11055	COG1024	Enoyl-CoA hydratase
J6598_11060	COG0183	Belongs to the thiolase family
J6598_11065	COG0714	Associated with various cellular activities
J6598_11085	COG2304	oxidoreductase activity
J6598_11095	COG1595	DNA-templated transcription, initiation
J6598_11105	COG2067	long-chain fatty acid transport protein
J6598_11110	COG2067	long-chain fatty acid transport protein
J6598_11115	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
J6598_11130	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
J6598_11140	COG1643	Atp-dependent helicase
J6598_11145	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
J6598_11145	COG0617	tRNA 3'-terminal CCA addition
J6598_11145	COG0517	IMP dehydrogenase activity
J6598_11150	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
J6598_11160	COG3119	arylsulfatase activity
J6598_11165	COG0714	Associated with various cellular activities
J6598_11180	COG2304	oxidoreductase activity
J6598_11185	COG2304	oxidoreductase activity
J6598_11210	COG0641	radical SAM
J6598_11215	COG2925	Exonuclease
J6598_11225	COG3345	alpha-galactosidase
J6598_11230	COG1380	Effector of murein hydrolase LrgA
J6598_11235	COG1346	cytolysis
J6598_11240	COG0295	cytidine deaminase activity
J6598_11250	COG3033	Beta-eliminating lyase
J6598_11260	COG3046	protein related to deoxyribodipyrimidine photolyase
J6598_11265	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
J6598_11270	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
J6598_11295	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
J6598_11305	COG3158	transport of potassium into the cell
J6598_11310	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
J6598_11315	COG0651	ATP synthesis coupled electron transport
J6598_11320	COG0650	Formate hydrogenlyase subunit 4
J6598_11325	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
J6598_11325	COG3261	NADH dehydrogenase
J6598_11330	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
J6598_11335	COG3260	NADH ubiquinone oxidoreductase 20
J6598_11345	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
J6598_11355	COG1921	L-seryl-tRNASec selenium transferase activity
J6598_11365	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
J6598_11370	COG0298	carbon dioxide binding
J6598_11380	COG0309	Hydrogenase expression formation protein (HypE)
J6598_11385	COG0375	protein maturation
J6598_11390	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
J6598_11395	COG1124	(ABC) transporter
J6598_11400	COG0444	Belongs to the ABC transporter superfamily
J6598_11405	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
J6598_11410	COG0601	transmembrane transport
J6598_11420	COG1773	rubredoxin
J6598_11425	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
J6598_11430	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
J6598_11435	COG5557	Pfam Polysulphide reductase, NrfD
J6598_11440	COG0437	4 iron, 4 sulfur cluster binding
J6598_11445	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
J6598_11450	COG5001	Diguanylate cyclase
J6598_11450	COG4251	negative regulation of phosphorylation
J6598_11450	COG3706	GGDEF domain
J6598_11450	COG2203	Gaf domain
J6598_11460	COG0297	glycogen (starch) synthase activity
J6598_11480	COG0438	transferase activity, transferring glycosyl groups
J6598_11525	COG0438	transferase activity, transferring glycosyl groups
J6598_11530	COG1215	transferase activity, transferring glycosyl groups
J6598_11535	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
J6598_11575	COG2205	protein histidine kinase activity
J6598_11575	COG0784	Response regulator, receiver
J6598_11585	COG0730	response to heat
J6598_11595	COG1028	Short-chain dehydrogenase reductase Sdr
J6598_11605	COG1024	Enoyl-CoA hydratase
J6598_11610	COG1024	Enoyl-CoA hydratase
J6598_11615	COG1960	acyl-CoA dehydrogenase activity
J6598_11620	COG1960	acyl-CoA dehydrogenase activity
J6598_11625	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
J6598_11630	COG1024	Enoyl-CoA hydratase
J6598_11660	COG1584	GPR1 FUN34 yaaH family protein
J6598_11675	COG1115	amino acid carrier protein
J6598_11680	COG1024	Enoyl-CoA hydratase
J6598_11695	COG3162	membrane
J6598_11700	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
J6598_11705	COG0488	(ABC) transporter
J6598_11710	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
J6598_11715	COG0776	regulation of translation
J6598_11720	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
J6598_11725	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
J6598_11730	COG0740	serine-type endopeptidase activity
J6598_11735	COG0544	peptidyl-prolyl cis-trans isomerase activity
J6598_11745	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
J6598_11750	COG4591	ABC-type transport system involved in lipoprotein release permease component
J6598_11755	COG1136	(ABC) transporter
J6598_11760	COG4591	ABC-type transport system involved in lipoprotein release permease component
J6598_11770	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
J6598_11775	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
J6598_11780	COG4166	transmembrane transport
J6598_11785	COG0697	spore germination
J6598_11795	COG2062	phosphohistidine phosphatase, SixA
J6598_11800	COG1025	Belongs to the peptidase M16 family
J6598_11825	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
J6598_11840	COG0518	GMP synthase (glutamine-hydrolyzing) activity
J6598_11840	COG0519	Catalyzes the synthesis of GMP from XMP
J6598_11845	COG0516	GMP reductase activity
J6598_11845	COG0517	IMP dehydrogenase activity
J6598_11855	COG1570	exodeoxyribonuclease VII activity
J6598_11860	COG2188	Transcriptional regulator
J6598_11865	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
J6598_11865	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
J6598_11865	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
J6598_11870	COG0383	alpha-mannosidase activity
J6598_11875	COG1181	Belongs to the D-alanine--D-alanine ligase family
J6598_11885	COG0386	Belongs to the glutathione peroxidase family
J6598_11890	COG0513	Belongs to the DEAD box helicase family
J6598_11905	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
J6598_11910	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
J6598_11915	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
J6598_11965	COG5001	Diguanylate cyclase
J6598_11965	COG3300	MHYT domain
J6598_11980	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
J6598_11990	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
J6598_11995	COG0563	adenylate kinase activity
J6598_12005	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
J6598_12010	COG1286	toxin biosynthetic process
J6598_12020	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
J6598_12025	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
J6598_12030	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
J6598_12035	COG0531	amino acid
J6598_12035	COG1674	ftsk spoiiie
J6598_12045	COG0686	Belongs to the AlaDH PNT family
J6598_12050	COG0492	ferredoxin-NADP+ reductase activity
J6598_12055	COG3706	GGDEF domain
J6598_12060	COG3134	Outer membrane lipoprotein
J6598_12065	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
J6598_12070	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
J6598_12075	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
J6598_12080	COG0542	response to heat
J6598_12085	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
J6598_12090	COG1278	Cold shock
J6598_12095	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
J6598_12115	COG0745	RESPONSE REGULATOR receiver
J6598_12120	COG2205	protein histidine kinase activity
J6598_12130	COG0392	lysyltransferase activity
J6598_12130	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
J6598_12145	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
J6598_12170	COG0659	secondary active sulfate transmembrane transporter activity
J6598_12225	COG0582	viral genome integration into host DNA
J6598_12235	COG2314	TM2 domain
J6598_12250	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
J6598_12250	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
J6598_12295	COG0672	)-iron permease
J6598_12320	COG2814	Major facilitator Superfamily
J6598_12340	COG0577	efflux transmembrane transporter activity
J6598_12350	COG1285	pathogenesis
J6598_12365	COG0596	Alpha beta hydrolase
J6598_12385	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
J6598_12390	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
J6598_12390	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
J6598_12395	COG0527	aspartate kinase activity
J6598_12405	COG1368	sulfuric ester hydrolase activity
J6598_12410	COG1619	proteins homologs of microcin C7 resistance protein MccF
J6598_12415	COG4667	esterase of the alpha-beta hydrolase superfamily
J6598_12435	COG1648	precorrin-2 dehydrogenase activity
J6598_12435	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
J6598_12445	COG0393	Putative heavy-metal-binding
J6598_12450	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
J6598_12455	COG0285	dihydrofolate synthase activity
J6598_12460	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
J6598_12465	COG0101	tRNA pseudouridine synthase activity
J6598_12475	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
J6598_12480	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
J6598_12485	COG0671	phosphoesterase, PA-phosphatase related
J6598_12490	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
J6598_12495	COG2056	Na+-H+ antiporter family
J6598_12500	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
J6598_12500	COG0047	phosphoribosylformylglycinamidine synthase activity
J6598_12505	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
J6598_12510	COG1645	bacterial-type flagellum-dependent swarming motility
J6598_12515	COG1160	GTP binding
J6598_12520	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
J6598_12525	COG2976	Protein conserved in bacteria
J6598_12530	COG0124	histidyl-tRNA synthetase
J6598_12535	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
J6598_12550	COG0820	rRNA (adenine-C2-)-methyltransferase activity
J6598_12555	COG0105	UTP biosynthetic process
J6598_12570	COG0633	Ferredoxin
J6598_12575	COG0443	Heat shock 70 kDa protein
J6598_12580	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
J6598_12590	COG0822	iron-sulfur transferase activity
J6598_12595	COG1104	cysteine desulfurase activity
J6598_12615	COG3154	lipid carrier protein
J6598_12620	COG0826	peptidase U32
J6598_12625	COG0826	peptidase U32
J6598_12640	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
J6598_12645	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
J6598_12650	COG1862	Preprotein translocase
J6598_12655	COG0343	queuine tRNA-ribosyltransferase activity
J6598_12660	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
J6598_12665	COG0517	IMP dehydrogenase activity
J6598_12675	COG3634	alkyl hydroperoxide reductase activity
J6598_12745	COG1242	4 iron, 4 sulfur cluster binding
J6598_12750	COG0067	glutamate synthase
J6598_12750	COG0069	glutamate synthase activity
J6598_12750	COG0070	glutamate synthase
J6598_12755	COG0493	'glutamate synthase
J6598_12765	COG0513	Belongs to the DEAD box helicase family
J6598_12790	COG0023	Translation Initiation Factor
J6598_12795	COG2119	membrane
J6598_12840	COG0215	cysteine-tRNA ligase activity
J6598_12845	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
J6598_12855	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
J6598_12885	COG0322	excinuclease ABC activity
J6598_12890	COG2197	response regulator
J6598_12895	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
J6598_12900	COG2835	tetraacyldisaccharide 4'-kinase activity
J6598_12905	COG1663	tetraacyldisaccharide 4'-kinase activity
J6598_12910	COG1132	(ABC) transporter
J6598_12915	COG0658	competence protein
J6598_12915	COG2333	competence protein COMEC
J6598_12935	COG1448	Aminotransferase
J6598_12945	COG0583	DNA-binding transcription factor activity
J6598_12950	COG3085	chromosome segregation
J6598_12955	COG4574	serine-type endopeptidase inhibitor activity
J6598_12960	COG0584	glycerophosphoryl diester phosphodiesterase
J6598_12970	COG1349	DNA-binding transcription factor activity
J6598_12975	COG2271	Major facilitator Superfamily
J6598_12980	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
J6598_12985	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
J6598_12990	COG0840	transmembrane signaling receptor activity
J6598_13000	COG0583	DNA-binding transcription factor activity
J6598_13015	COG0656	L-ascorbic acid biosynthetic process
J6598_13025	COG2814	Major facilitator Superfamily
J6598_13035	COG1294	oxidase, subunit
J6598_13045	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
J6598_13050	COG2979	Protein of unknown function (DUF533)
J6598_13065	COG0583	DNA-binding transcription factor activity
J6598_13070	COG2807	transmembrane transport
J6598_13075	COG1187	pseudouridine synthase activity
J6598_13095	COG1403	HNH endonuclease
J6598_13100	COG4657	Part of a membrane complex involved in electron transport
J6598_13105	COG2878	Part of a membrane complex involved in electron transport
J6598_13115	COG4658	electron transport chain
J6598_13120	COG4659	FMN binding
J6598_13125	COG4660	Part of a membrane complex involved in electron transport
J6598_13130	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
J6598_13135	COG0346	lactoylglutathione lyase activity
J6598_13175	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
J6598_13180	COG0505	Belongs to the CarA family
J6598_13185	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
J6598_13200	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
J6598_13205	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
J6598_13210	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
J6598_13215	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
J6598_13220	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
J6598_13230	COG4138	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system
J6598_13260	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
J6598_13265	COG0861	Integral membrane protein TerC family
J6598_13280	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
J6598_13285	COG0601	transmembrane transport
J6598_13295	COG2095	MarC family integral membrane protein
J6598_13300	COG1012	belongs to the aldehyde dehydrogenase family
J6598_13300	COG1454	alcohol dehydrogenase
J6598_13330	COG0217	transcriptional regulatory protein
J6598_13335	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
J6598_13345	COG1801	Protein of unknown function DUF72
J6598_13350	COG4106	trans-aconitate 2-methyltransferase activity
J6598_13355	COG0500	methyltransferase
J6598_13375	COG0450	alkyl hydroperoxide reductase
J6598_13380	COG0583	DNA-binding transcription factor activity
J6598_13385	COG0791	NLP P60 protein
J6598_13395	COG0583	DNA-binding transcription factor activity
J6598_13400	COG2610	gluconate transmembrane transporter activity
J6598_13405	COG3048	D-serine ammonia-lyase activity
J6598_13415	COG0538	isocitrate dehydrogenase activity
J6598_13420	COG2207	Transcriptional regulator
J6598_13435	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
J6598_13450	COG3152	Membrane
J6598_13455	COG2814	Major facilitator Superfamily
J6598_13460	COG0109	protoheme IX farnesyltransferase activity
J6598_13465	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
J6598_13470	COG1845	cytochrome c oxidase, subunit III
J6598_13475	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
J6598_13480	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
J6598_13515	COG1309	transcriptional regulator
J6598_13545	COG0534	Mate efflux family protein
J6598_13555	COG2841	Protein conserved in bacteria
J6598_13565	COG5001	Diguanylate cyclase
J6598_13565	COG3300	MHYT domain
J6598_13570	COG3132	Protein of unknown function, DUF480
J6598_13600	COG0708	Exodeoxyribonuclease III
J6598_13635	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
J6598_13640	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
J6598_13650	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
J6598_13655	COG1120	ATPase activity
J6598_13660	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
J6598_13665	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
J6598_13670	COG2375	cellular response to nickel ion
J6598_13675	COG3437	response regulator, receiver
J6598_13675	COG0784	Response regulator, receiver
J6598_13685	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
J6598_13690	COG0328	RNA-DNA hybrid ribonuclease activity
J6598_13695	COG2226	methyltransferase
J6598_13700	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
J6598_13705	COG0741	lytic transglycosylase activity
J6598_13705	COG1388	LysM domain
J6598_13730	COG5000	phosphorelay sensor kinase activity
J6598_13730	COG5002	protein histidine kinase activity
J6598_13735	COG0745	RESPONSE REGULATOR receiver
J6598_13740	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
J6598_13745	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
J6598_13760	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
J6598_13760	COG2199	diguanylate cyclase activity
J6598_13765	COG3275	phosphorelay sensor kinase activity
J6598_13770	COG3279	Response regulator of the LytR AlgR family
J6598_13775	COG1966	Carbon starvation protein
J6598_13785	COG1566	PFAM secretion protein HlyD family protein
J6598_13790	COG1061	Type III restriction enzyme res subunit
J6598_13795	COG2027	D-alanyl-D-alanine carboxypeptidase
J6598_13800	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
J6598_13805	COG3021	interspecies interaction between organisms
J6598_13815	COG1607	acyl-coa hydrolase
J6598_13820	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
J6598_13830	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
J6598_13830	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
J6598_13830	COG0674	pyruvate-flavodoxin oxidoreductase activity
J6598_13830	COG1013	pyruvate-flavodoxin oxidoreductase activity
J6598_13845	COG0633	Ferredoxin
J6598_13845	COG3217	Mosc domain protein beta barrel domain protein
J6598_13845	COG0633	Ferredoxin
J6598_13845	COG3217	Mosc domain protein beta barrel domain protein
J6598_13855	COG0501	Belongs to the peptidase M48B family
J6598_13860	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
J6598_13865	COG1073	alpha beta
J6598_13865	COG2226	methyltransferase
J6598_13870	COG0156	8-amino-7-oxononanoate synthase activity
J6598_13875	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
J6598_13880	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
J6598_13895	COG0017	Asparaginyl-tRNA synthetase
J6598_13905	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
J6598_13915	COG1473	amidohydrolase
J6598_13920	COG3069	C4-dicarboxylate transmembrane transporter activity
J6598_13930	COG1393	Belongs to the ArsC family
J6598_13935	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
J6598_13940	COG1876	peptidase activity
J6598_13950	COG3263	regulation of cellular component size
J6598_13965	COG1280	lysine exporter protein (LysE YggA)
J6598_14000	COG0564	pseudouridine synthase activity
J6598_14010	COG1454	alcohol dehydrogenase
J6598_14050	COG2894	cell division
J6598_14060	COG4964	Belongs to the GSP D family
J6598_14090	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
J6598_14095	COG0702	epimerase
J6598_14105	COG0095	Lipoate-protein ligase
J6598_14115	COG0577	efflux transmembrane transporter activity
J6598_14115	COG1136	(ABC) transporter
J6598_14120	COG0577	efflux transmembrane transporter activity
J6598_14120	COG1136	(ABC) transporter
J6598_14125	COG0577	efflux transmembrane transporter activity
J6598_14125	COG1136	(ABC) transporter
J6598_14130	COG1566	PFAM secretion protein HlyD family protein
J6598_14170	COG1285	pathogenesis
J6598_14200	COG0484	heat shock protein binding
J6598_14205	COG0443	Heat shock 70 kDa protein
J6598_14210	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
J6598_14215	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
J6598_14220	COG0497	DNA recombination
J6598_14225	COG1227	inorganic diphosphatase activity
J6598_14230	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
J6598_14235	COG0577	efflux transmembrane transporter activity
J6598_14235	COG1136	(ABC) transporter
J6598_14255	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
J6598_14270	COG1215	transferase activity, transferring glycosyl groups
J6598_14285	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
J6598_14300	COG0529	Catalyzes the synthesis of activated sulfate
J6598_14305	COG0471	metal ion transport
J6598_14305	COG0490	domain, Protein
J6598_14310	COG2895	sulfate adenylyltransferase (ATP) activity
J6598_14340	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
J6598_14350	COG1450	Type ii and iii secretion system protein
J6598_14385	COG2165	general secretion pathway protein
J6598_14395	COG1459	type II secretion system
J6598_14420	COG1091	dTDP-4-dehydrorhamnose reductase activity
J6598_14430	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
J6598_14435	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
J6598_14440	COG1309	transcriptional regulator
J6598_14455	COG1342	Belongs to the UPF0251 family
J6598_14475	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
J6598_14495	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
J6598_14500	COG0083	homoserine kinase activity
J6598_14510	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
J6598_14515	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
J6598_14520	COG1946	Acyl-CoA thioesterase
J6598_14535	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
J6598_14545	COG0009	L-threonylcarbamoyladenylate synthase
J6598_14555	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
J6598_14565	COG0512	Glutamine amidotransferase of anthranilate synthase
J6598_14565	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
J6598_14570	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
J6598_14575	COG0135	phosphoribosylanthranilate isomerase activity
J6598_14575	COG0134	indole-3-glycerol-phosphate synthase activity
J6598_14580	COG0133	tryptophan synthase activity
J6598_14585	COG0159	tryptophan synthase activity
J6598_14600	COG1988	membrane-bound metal-dependent
J6598_14615	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
J6598_14635	COG0798	PFAM Bile acid sodium symporter
J6598_14665	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
J6598_14675	COG0745	RESPONSE REGULATOR receiver
J6598_14690	COG4988	ABC transporter
J6598_14695	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
J6598_14715	COG1720	tRNA m6t6A37 methyltransferase activity
J6598_14720	COG3038	cytochrome b561
J6598_14740	COG2862	Uncharacterized protein family, UPF0114
J6598_14755	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
J6598_14760	COG1396	sequence-specific DNA binding
J6598_14760	COG1917	Cupin 2, conserved barrel domain protein
J6598_14775	COG0531	amino acid
J6598_14785	COG0531	amino acid
J6598_14795	COG1283	sodium-dependent phosphate transmembrane transporter activity
J6598_14800	COG0545	Peptidyl-prolyl cis-trans isomerase
J6598_14805	COG0405	Gamma-glutamyltransferase
J6598_14810	COG2974	May be involved in recombination
J6598_14820	COG0420	3'-5' exonuclease activity
J6598_14825	COG0419	ATPase involved in DNA repair
J6598_14830	COG3384	dioxygenase
J6598_14840	COG0469	pyruvate kinase activity
J6598_14845	COG1196	nuclear chromosome segregation
J6598_14845	COG3264	Mechanosensitive ion channel
J6598_14855	COG3590	peptidase
J6598_14865	COG2190	(PTS) system
J6598_14875	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
J6598_14880	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
J6598_14885	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
J6598_14900	COG2770	Histidine kinase
J6598_14900	COG3437	response regulator, receiver
J6598_14905	COG3267	Type II secretory pathway component ExeA
J6598_14905	COG3409	Peptidoglycan-binding domain 1 protein
J6598_14925	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
J6598_14930	COG1459	type II secretion system
J6598_14935	COG2165	general secretion pathway protein
J6598_14945	COG2165	general secretion pathway protein
J6598_14950	COG4795	General secretion pathway protein
J6598_14955	COG3156	type II secretion system protein K
J6598_14965	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
J6598_14980	COG0670	Belongs to the BI1 family
J6598_14985	COG1289	transmembrane transporter activity
J6598_14990	COG2920	part of a sulfur-relay system
J6598_14995	COG0673	inositol 2-dehydrogenase activity
J6598_15000	COG0583	DNA-binding transcription factor activity
J6598_15025	COG1032	radical SAM domain protein
J6598_15035	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
J6598_15040	COG3706	GGDEF domain
J6598_15045	COG1752	Esterase of the alpha-beta hydrolase superfamily
J6598_15050	COG0531	amino acid
J6598_15075	COG0281	malic enzyme
J6598_15085	COG0534	Mate efflux family protein
J6598_15100	COG2233	PERMEase
J6598_15105	COG0095	Lipoate-protein ligase
J6598_15110	COG1115	amino acid carrier protein
J6598_15115	COG0019	diaminopimelate decarboxylase activity
J6598_15125	COG0678	peroxiredoxin activity
J6598_15150	COG0545	Peptidyl-prolyl cis-trans isomerase
J6598_15155	COG3142	Participates in the control of copper homeostasis
J6598_15180	COG5002	protein histidine kinase activity
J6598_15185	COG0745	RESPONSE REGULATOR receiver
J6598_15190	COG0346	lactoylglutathione lyase activity
J6598_15210	COG0697	spore germination
J6598_15220	COG3290	protein histidine kinase activity
J6598_15225	COG0281	malic enzyme
J6598_15235	COG1846	Transcriptional regulator
J6598_15240	COG1566	PFAM secretion protein HlyD family protein
J6598_15270	COG0602	queuosine metabolic process
J6598_15275	COG1328	CTP reductase activity
J6598_15285	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
J6598_15290	COG3115	cell septum assembly
J6598_15295	COG1196	nuclear chromosome segregation
J6598_15305	COG2860	membrane
J6598_15315	COG3108	Peptidase M15
J6598_15320	COG2989	Protein conserved in bacteria
J6598_15335	COG0463	Glycosyl transferase, family 2
J6598_15350	COG0366	Alpha amylase catalytic
J6598_15385	COG2199	diguanylate cyclase activity
J6598_15385	COG2203	Gaf domain
J6598_15395	COG3590	peptidase
J6598_15405	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
J6598_15410	COG1982	Orn Lys Arg decarboxylase major
J6598_15415	COG0531	amino acid
J6598_15420	COG3710	Transcriptional regulator
J6598_15425	COG0531	amino acid
J6598_15450	COG0814	amino acid
J6598_15480	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
J6598_15485	COG0739	heme binding
J6598_15490	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
J6598_15500	COG0251	oxidation-reduction process
J6598_15515	COG0583	DNA-binding transcription factor activity
J6598_15520	COG0604	alcohol dehydrogenase
J6598_15520	COG1028	Short-chain dehydrogenase reductase Sdr
J6598_15520	COG3321	synthase
J6598_15530	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
J6598_15540	COG3091	SprT-like family
J6598_15550	COG1385	rRNA (uridine-N3-)-methyltransferase activity
J6598_15555	COG0189	ligase activity
J6598_15560	COG1678	Uncharacterized ACR, COG1678
J6598_15565	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
J6598_15570	COG3104	oligopeptide transport
J6598_15585	COG0714	Associated with various cellular activities
J6598_15600	COG1115	amino acid carrier protein
J6598_15605	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
J6598_15615	COG0825	malonyl-CoA metabolic process
J6598_15625	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
J6598_15630	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
J6598_15635	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
J6598_15640	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
J6598_15645	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
J6598_15660	COG0750	zinc metalloprotease
J6598_15665	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
J6598_15670	COG0575	Belongs to the CDS family
J6598_15675	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
J6598_15680	COG0233	cytoplasmic translational termination
J6598_15685	COG0528	UMP kinase activity
J6598_15690	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
J6598_15695	COG0052	Belongs to the universal ribosomal protein uS2 family
J6598_15700	COG0024	Methionine aminopeptidase
J6598_15710	COG2171	N-acyltransferase activity
J6598_15720	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
J6598_15720	COG1263	PTS System
J6598_15740	COG0564	pseudouridine synthase activity
J6598_15745	COG3098	single-species biofilm formation
J6598_15770	COG5595	Zn-ribbon-containing, possibly nucleic-acid-binding protein (DUF2310)
J6598_15780	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
J6598_15780	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
J6598_15795	COG1611	Belongs to the LOG family
J6598_15800	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
J6598_15805	COG0473	3-isopropylmalate dehydrogenase activity
J6598_15815	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
J6598_15820	COG2363	Small membrane protein
J6598_15830	COG0583	DNA-binding transcription factor activity
J6598_15835	COG0840	transmembrane signaling receptor activity
J6598_15840	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
J6598_15855	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
J6598_15860	COG1666	GTP binding
J6598_15865	COG3248	Nucleoside-binding outer membrane protein
J6598_15870	COG2211	Major facilitator Superfamily
J6598_15875	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
J6598_15885	COG2813	Specifically methylates the guanine in position
J6598_15890	COG0271	Belongs to the BolA IbaG family
J6598_15895	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
J6598_15900	COG1805	sodium ion transport
J6598_15905	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
J6598_15910	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
J6598_15915	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
J6598_15920	COG2871	sodium ion transport
J6598_15925	COG1477	protein flavinylation
J6598_15955	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
J6598_15970	COG0300	oxidoreductase activity
J6598_15980	COG0415	Belongs to the DNA photolyase family
J6598_15985	COG0789	Transcriptional regulator
J6598_15990	COG3272	Protein of unknown function (DUF1722)
J6598_16020	COG0077	Prephenate dehydratase
J6598_16020	COG1605	Chorismate mutase
J6598_16050	COG5377	YqaJ viral recombinase family
J6598_16095	COG2003	Belongs to the UPF0758 family
J6598_16110	COG0469	pyruvate kinase activity
J6598_16120	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
J6598_16120	COG1263	PTS System
J6598_16125	COG1874	Beta-galactosidase
J6598_16130	COG3867	Arabinogalactan endo-beta-1,4-galactanase
J6598_16135	COG3833	ABC-type maltose transport systems, permease component
J6598_16140	COG1175	transmembrane transport
J6598_16145	COG2182	Extracellular solute-binding protein
J6598_16170	COG4580	involved in the transport of maltose and maltodextrins
J6598_16175	COG1609	Transcriptional regulator
J6598_16180	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
J6598_16185	COG1085	galactose-1-phosphate uridylyltransferase
J6598_16225	COG0840	transmembrane signaling receptor activity
J6598_16235	COG0300	oxidoreductase activity
J6598_16260	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
J6598_16310	COG0826	peptidase U32
J6598_16315	COG1280	lysine exporter protein (LysE YggA)
J6598_16325	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
J6598_16335	COG0745	RESPONSE REGULATOR receiver
J6598_16345	COG2198	Histidine kinase
J6598_16345	COG0643	Histidine kinase
J6598_16355	COG0835	chemotaxis
J6598_16360	COG0840	transmembrane signaling receptor activity
J6598_16370	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
J6598_16375	COG2201	protein-glutamate methylesterase activity
J6598_16380	COG1185	polyribonucleotide nucleotidyltransferase activity
J6598_16385	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
J6598_16390	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
J6598_16395	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
J6598_16400	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
J6598_16405	COG0195	Participates in both transcription termination and antitermination
J6598_16410	COG0779	Required for maturation of 30S ribosomal subunits
J6598_16425	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
J6598_16430	COG0149	triose-phosphate isomerase activity
J6598_16435	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
J6598_16440	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
J6598_16450	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
J6598_16455	COG1534	Rna-binding protein
J6598_16470	COG1360	Flagellar Motor Protein
J6598_16475	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
J6598_16480	COG1722	exodeoxyribonuclease VII activity
J6598_16485	COG0142	geranyltranstransferase activity
J6598_16490	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
J6598_16500	COG0601	transmembrane transport
J6598_16515	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
J6598_16520	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
J6598_16525	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
J6598_16530	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
J6598_16550	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
J6598_16550	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
J6598_16555	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
J6598_16560	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
J6598_16570	COG0784	Response regulator, receiver
J6598_16570	COG2198	Histidine kinase
J6598_16570	COG2205	protein histidine kinase activity
J6598_16575	COG1879	ABC-type sugar transport system periplasmic component
J6598_16585	COG0745	RESPONSE REGULATOR receiver
J6598_16590	COG3005	denitrification pathway
J6598_16600	COG3381	protein complex oligomerization
J6598_16615	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
J6598_16620	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
J6598_16625	COG0511	ligase activity, forming carbon-carbon bonds
J6598_16630	COG0439	Biotin carboxylase
J6598_16640	COG4145	pantothenate transmembrane transporter activity
J6598_16645	COG2190	(PTS) system
J6598_16645	COG1263	PTS System
J6598_16645	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
J6598_16650	COG0583	DNA-binding transcription factor activity
J6598_16655	COG0604	alcohol dehydrogenase
J6598_16660	COG2264	protein methyltransferase activity
J6598_16665	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
J6598_16670	COG0110	maltose O-acetyltransferase activity
J6598_16675	COG0778	Nitroreductase
J6598_16680	COG0446	pyridine nucleotide-disulphide oxidoreductase
J6598_16680	COG1902	pentaerythritol trinitrate reductase activity
J6598_16685	COG0616	signal peptide processing
J6598_16705	COG0848	biopolymer transport protein
J6598_16710	COG0811	peptide transport
J6598_16715	COG0811	peptide transport
J6598_16730	COG4174	ABC transporter (Permease)
J6598_16735	COG4239	(ABC) transporter, permease
J6598_16745	COG0444	Belongs to the ABC transporter superfamily
J6598_16750	COG4608	Belongs to the ABC transporter superfamily
J6598_16770	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
J6598_16775	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
J6598_16780	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
J6598_16790	COG3416	Protein conserved in bacteria
J6598_16800	COG0741	lytic transglycosylase activity
J6598_16815	COG0488	(ABC) transporter
J6598_16825	COG2252	PERMEase
J6598_16830	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
J6598_16835	COG0840	transmembrane signaling receptor activity
J6598_16845	COG1278	Cold shock
J6598_16885	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
J6598_16890	COG1162	GTPase activity
J6598_16895	COG0688	phosphatidylethanolamine metabolic process
J6598_16900	COG4628	conserved protein (DUF2132)
J6598_16915	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
J6598_16930	COG1073	alpha beta
J6598_16935	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
J6598_16940	COG2195	Cleaves the N-terminal amino acid of tripeptides
J6598_16945	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
J6598_16950	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
J6598_16955	COG3178	'Phosphotransferase
J6598_16960	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
J6598_16965	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
J6598_16970	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
J6598_16975	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
J6598_16980	COG2967	ApaG domain
J6598_16985	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
J6598_17000	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
J6598_17015	COG3314	Sporulation integral membrane protein YlbJ
J6598_17020	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
J6598_17025	COG0211	Belongs to the bacterial ribosomal protein bL27 family
J6598_17030	COG0261	This protein binds to 23S rRNA in the presence of protein L20
J6598_17035	COG0142	geranyltranstransferase activity
J6598_17040	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
J6598_17045	COG0330	HflC and HflK could
J6598_17050	COG0330	HflC and HflK could
J6598_17055	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
J6598_17060	COG1923	regulation of RNA biosynthetic process
J6598_17065	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
J6598_17070	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
J6598_17075	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
J6598_17085	COG0802	atpase or kinase
J6598_17090	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
J6598_17090	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
J6598_17110	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
J6598_17115	COG2011	ABC-type metal ion transport system permease component
J6598_17120	COG1464	Belongs to the NlpA lipoprotein family
J6598_17130	COG0840	transmembrane signaling receptor activity
J6598_17155	COG2198	Histidine kinase
J6598_17155	COG5002	protein histidine kinase activity
J6598_17155	COG0784	Response regulator, receiver
J6598_17190	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
J6598_17195	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
J6598_17200	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
J6598_17205	COG2716	regulation of RNA biosynthetic process
J6598_17210	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
J6598_17215	COG3013	Belongs to the UPF0304 family
J6598_17225	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
J6598_17230	COG0280	phosphate acetyltransferase
J6598_17230	COG0857	belongs to the CobB CobQ family
J6598_17235	COG1555	photosystem II stabilization
J6598_17240	COG1210	Utp--glucose-1-phosphate uridylyltransferase
J6598_17245	COG3104	oligopeptide transport
J6598_17255	COG0745	RESPONSE REGULATOR receiver
J6598_17285	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
J6598_17300	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
J6598_17335	COG0440	acetolactate synthase activity
J6598_17340	COG0028	Belongs to the TPP enzyme family
J6598_17370	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
J6598_17375	COG0473	3-isopropylmalate dehydrogenase activity
J6598_17380	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
J6598_17385	COG0066	3-isopropylmalate dehydratase activity
J6598_17400	COG4143	(ABC) transporter
J6598_17410	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
J6598_17415	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
J6598_17465	COG0459	protein refolding
J6598_17470	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
J6598_17475	COG0534	Mate efflux family protein
J6598_17480	COG3030	protein affecting phage T7 exclusion by the F plasmid
J6598_17485	COG1027	Aspartate ammonia-lyase
J6598_17490	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
J6598_17495	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
J6598_17500	COG0828	Belongs to the bacterial ribosomal protein bS21 family
J6598_17505	COG1610	YqeY-like protein
J6598_17510	COG0358	DNA primase activity
J6598_17515	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
J6598_17535	COG0151	Belongs to the GarS family
J6598_17540	COG0138	bifunctional purine biosynthesis protein purh
J6598_17550	COG3036	rescue of stalled ribosome
J6598_17555	COG0635	Involved in the biosynthesis of porphyrin-containing compound
J6598_17560	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
J6598_17570	COG0673	inositol 2-dehydrogenase activity
J6598_17580	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
J6598_17585	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
J6598_17595	COG0583	DNA-binding transcription factor activity
J6598_17600	COG0477	Major facilitator Superfamily
J6598_17620	COG1028	Short-chain dehydrogenase reductase Sdr
J6598_17630	COG2425	protein containing a von Willebrand factor type A (vWA) domain
J6598_17655	COG1022	Amp-dependent synthetase and ligase
J6598_17660	COG2918	glutathione biosynthetic process
J6598_17665	COG0612	Peptidase, M16
J6598_17670	COG1238	metal cluster binding
J6598_17675	COG1064	alcohol dehydrogenase
J6598_17700	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
J6598_17705	COG0359	binds to the 23S rRNA
J6598_17710	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
J6598_17715	COG0360	Binds together with S18 to 16S ribosomal RNA
J6598_17720	COG1914	H( )-stimulated, divalent metal cation uptake system
J6598_17725	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
J6598_17735	COG0776	regulation of translation
J6598_17750	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
J6598_17765	COG0560	Phosphoserine phosphatase
J6598_17775	COG0813	purine-nucleoside phosphorylase activity
J6598_17780	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
J6598_17785	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
J6598_17790	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
J6598_17800	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
J6598_17805	COG0084	hydrolase, TatD family'
J6598_17810	COG2165	general secretion pathway protein
J6598_17820	COG1854	S-ribosylhomocysteine lyase activity
J6598_17835	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
J6598_17835	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
J6598_17880	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
J6598_17885	COG1047	Peptidyl-prolyl cis-trans
J6598_17890	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
J6598_17895	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
J6598_17900	COG0196	riboflavin kinase activity
J6598_17905	COG0728	peptidoglycan biosynthetic process
J6598_17910	COG0268	Binds directly to 16S ribosomal RNA
J6598_17915	COG0640	Transcriptional regulator
J6598_17920	COG0583	DNA-binding transcription factor activity
J6598_17930	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
J6598_17935	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
J6598_17940	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
J6598_17950	COG1051	belongs to the nudix hydrolase family
J6598_17955	COG3066	DNA modification
J6598_17970	COG0335	large ribosomal subunit rRNA binding
J6598_17975	COG0336	Belongs to the RNA methyltransferase TrmD family
J6598_17980	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
J6598_17985	COG0228	four-way junction DNA binding
J6598_17990	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
J6598_17995	COG4137	Cytochrome C assembly protein
J6598_18000	COG4536	flavin adenine dinucleotide binding
J6598_18010	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
J6598_18010	COG1017	nitric oxide dioxygenase activity
J6598_18015	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
J6598_18020	COG0039	L-malate dehydrogenase activity
J6598_18025	COG4160	amino acid transport
J6598_18030	COG4215	(ABC) transporter
J6598_18035	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
J6598_18040	COG1126	abc transporter atp-binding protein
J6598_18045	COG1438	arginine binding
J6598_18050	COG2837	iron assimilation
J6598_18055	COG3842	ATPase activity
J6598_18065	COG1840	ABC-type Fe3 transport system, periplasmic component
J6598_18070	COG0347	Belongs to the P(II) protein family
J6598_18090	COG3022	response to hydroperoxide
J6598_18105	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
J6598_18110	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
J6598_18115	COG0762	integral membrane protein
J6598_18120	COG1872	DUF167
J6598_18130	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
J6598_18135	COG0583	DNA-binding transcription factor activity
J6598_18150	COG1929	Belongs to the glycerate kinase type-1 family
J6598_18155	COG2610	gluconate transmembrane transporter activity
J6598_18160	COG3835	regulator
J6598_18165	COG3112	Uncharacterised protein family (UPF0231)
J6598_18185	COG3568	Endonuclease Exonuclease Phosphatase
J6598_18195	COG0513	Belongs to the DEAD box helicase family
J6598_18235	COG1448	Aminotransferase
J6598_18250	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
J6598_18255	COG1328	CTP reductase activity
J6598_18280	COG0543	2 iron, 2 sulfur cluster binding
J6598_18280	COG0633	Ferredoxin
J6598_18295	COG1215	transferase activity, transferring glycosyl groups
J6598_18300	COG0726	polysaccharide deacetylase
J6598_18300	COG1649	PFAM Uncharacterised BCR, COG1649
J6598_18315	COG0840	transmembrane signaling receptor activity
J6598_18320	COG3397	chitin binding
J6598_18325	COG0583	DNA-binding transcription factor activity
J6598_18330	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
J6598_18335	COG4208	sulfate ABC transporter
J6598_18340	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
J6598_18350	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
J6598_18355	COG3174	membrane
J6598_18360	COG0110	maltose O-acetyltransferase activity
J6598_18375	COG1011	Hydrolase
J6598_18380	COG0494	nUDIX hydrolase
J6598_18385	COG1218	3'(2'),5'-bisphosphate nucleotidase
J6598_18390	COG0814	amino acid
J6598_18395	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
J6598_18410	COG0626	cystathionine gamma-synthase activity
J6598_18415	COG0527	aspartate kinase activity
J6598_18415	COG0460	homoserine dehydrogenase
J6598_18420	COG0306	phosphate transporter
J6598_18425	COG1392	Phosphate transport regulator
J6598_18435	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
J6598_18440	COG2813	Specifically methylates the guanine in position
J6598_18445	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
J6598_18450	COG0297	glycogen (starch) synthase activity
J6598_18490	COG1757	Na H antiporter
J6598_18495	COG0316	Belongs to the HesB IscA family
J6598_18505	COG0038	chloride channel
J6598_18510	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
J6598_18525	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
J6598_18525	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
J6598_18560	COG1396	sequence-specific DNA binding
J6598_18565	COG3135	benzoate transporter
J6598_18590	COG0840	transmembrane signaling receptor activity
J6598_18595	COG3047	cAMP biosynthetic process
J6598_18600	COG2199	diguanylate cyclase activity
J6598_18605	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
J6598_18640	COG2197	response regulator
J6598_18655	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
J6598_18665	COG1278	Cold shock
J6598_18670	COG2252	PERMEase
J6598_18675	COG2376	Dihydroxyacetone kinase
J6598_18680	COG1461	Dihydroxyacetone kinase
J6598_18685	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
J6598_18685	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
J6598_18685	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
J6598_18695	COG3284	Transcriptional regulator
J6598_18705	COG0628	permease
J6598_18710	COG0494	nUDIX hydrolase
J6598_18725	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
J6598_18730	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
J6598_18750	COG0456	acetyltransferase
J6598_18755	COG3133	Outer membrane lipoprotein
J6598_18760	COG0004	ammonium transporteR
J6598_18765	COG3706	GGDEF domain
J6598_18775	COG3932	Exopolysaccharide synthesis, ExoD
J6598_18780	COG0814	amino acid
J6598_18795	COG0110	maltose O-acetyltransferase activity
J6598_18820	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
J6598_18825	COG2022	thiamine diphosphate biosynthetic process
J6598_18835	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
J6598_18840	COG0352	thiamine-phosphate diphosphorylase activity
J6598_18845	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
J6598_18865	COG0745	RESPONSE REGULATOR receiver
J6598_18870	COG0642	Histidine kinase
J6598_18875	COG0189	ligase activity
J6598_18920	COG0477	Major facilitator Superfamily
J6598_18935	COG0312	modulator of DNA gyrase
J6598_18940	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
J6598_18950	COG3164	Protein of unknown function
J6598_18955	COG1530	ribonuclease E activity
J6598_18960	COG0424	maF-like protein
J6598_18965	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
J6598_18970	COG1792	Involved in formation and maintenance of cell shape
J6598_18975	COG1077	Cell shape determining protein MreB Mrl
J6598_19000	COG4968	Prepilin-type N-terminal cleavage methylation domain
J6598_19005	COG2165	general secretion pathway protein
J6598_19020	COG1459	type II secretion system
J6598_19025	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
J6598_19070	COG2200	EAL domain
J6598_19070	COG2199	diguanylate cyclase activity
J6598_19075	COG2200	EAL domain
J6598_19080	COG0387	Pfam Sodium calcium exchanger
J6598_19085	COG2986	histidine ammonia-lyase
J6598_19090	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
J6598_19095	COG0010	Belongs to the arginase family
J6598_19100	COG1228	amidohydrolase
J6598_19105	COG2188	Transcriptional regulator
J6598_19110	COG0288	reversible hydration of carbon dioxide
J6598_19120	COG2177	Part of the ABC transporter FtsEX involved in
J6598_19125	COG2884	Cell division ATP-binding protein ftsE
J6598_19130	COG0552	protein localization to endoplasmic reticulum
J6598_19135	COG0742	ribosomal rna small subunit methyltransferase
J6598_19160	COG2249	NAD(P)H dehydrogenase (quinone) activity
J6598_19165	COG0583	DNA-binding transcription factor activity
J6598_19170	COG4221	oxidoreductase activity
J6598_19185	COG1770	oligopeptidase
J6598_19200	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
J6598_19210	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
J6598_19220	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
J6598_19230	COG2095	MarC family integral membrane protein
J6598_19240	COG1301	dicarboxylic acid transport
J6598_19265	COG3714	YhhN family
J6598_19335	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
J6598_19340	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
J6598_19345	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
J6598_19350	COG0049	tRNA binding
J6598_19355	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
J6598_19360	COG2168	tRNA wobble position uridine thiolation
J6598_19365	COG2923	Belongs to the DsrF TusC family
J6598_19370	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
J6598_19380	COG2964	Protein conserved in bacteria
J6598_19385	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
J6598_19390	COG0085	RNA polymerase activity
J6598_19395	COG0222	ribosome binding
J6598_19400	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
J6598_19405	COG0081	regulation of translation
J6598_19410	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
J6598_19415	COG0250	Participates in transcription elongation, termination and antitermination
J6598_19430	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
J6598_19455	COG0812	UDP-N-acetylmuramate dehydrogenase activity
J6598_19460	COG0569	domain protein
J6598_19465	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
J6598_19495	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
J6598_19495	COG4191	Histidine kinase
J6598_19500	COG3005	denitrification pathway
J6598_19505	COG0243	molybdopterin cofactor binding
J6598_19550	COG2204	response regulator
J6598_19560	COG2205	protein histidine kinase activity
J6598_19575	COG1028	Short-chain dehydrogenase reductase Sdr
J6598_19580	COG0517	IMP dehydrogenase activity
J6598_19580	COG0516	GMP reductase activity
J6598_19585	COG5413	integral membrane protein
J6598_19595	COG1522	sequence-specific DNA binding
J6598_19600	COG2502	aspartate--ammonia ligase
J6598_19605	COG0542	response to heat
J6598_19615	COG0564	pseudouridine synthase activity
J6598_19620	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
J6598_19625	COG0446	pyridine nucleotide-disulphide oxidoreductase
J6598_19635	COG3681	Belongs to the UPF0597 family
J6598_19640	COG2964	Protein conserved in bacteria
J6598_19650	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
J6598_19655	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
J6598_19660	COG1979	alcohol dehydrogenase
J6598_19665	COG2207	Transcriptional regulator
J6598_19685	COG0583	DNA-binding transcription factor activity
J6598_19705	COG0540	Belongs to the ATCase OTCase family
J6598_19710	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
J6598_19715	COG1438	arginine binding
J6598_19720	COG1288	antiporter activity
J6598_19725	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
J6598_19755	COG0635	Involved in the biosynthesis of porphyrin-containing compound
J6598_19765	COG3078	GTPase activator activity
J6598_19775	COG0218	Necessary for normal cell division and for the maintenance of normal septation
J6598_19785	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
J6598_19790	COG0408	coproporphyrinogen oxidase activity
J6598_19795	COG0009	L-threonylcarbamoyladenylate synthase
J6598_19805	COG0551	DNA topoisomerase type I activity
J6598_19810	COG2922	Belongs to the Smg family
J6598_19815	COG0758	DNA mediated transformation
J6598_19820	COG1652	LysM domain
J6598_19825	COG0242	peptide deformylase activity
J6598_19830	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
J6598_19835	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
J6598_19835	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
J6598_19840	COG0569	domain protein
J6598_19845	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
J6598_19850	COG1217	gtp-binding protein TYPA
J6598_19855	COG0174	glutamine synthetase
J6598_19870	COG2204	response regulator
J6598_19875	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
J6598_19880	COG1322	Protein conserved in bacteria
J6598_19900	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
J6598_19905	COG0583	DNA-binding transcription factor activity
J6598_19910	COG0518	GMP synthase (glutamine-hydrolyzing) activity
J6598_19910	COG0519	Catalyzes the synthesis of GMP from XMP
J6598_19920	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
J6598_19925	COG1396	sequence-specific DNA binding
J6598_19930	COG1012	belongs to the aldehyde dehydrogenase family
J6598_19940	COG2962	Rard protein
J6598_19950	COG2391	methyltransferase activity
J6598_19965	COG0129	dihydroxy-acid dehydratase activity
J6598_19975	COG3978	acetolactate synthase activity
J6598_19985	COG0606	chelatase, subunit chli
J6598_19990	COG0204	Acyl-transferase
J6598_19995	COG0204	Acyl-transferase
J6598_20000	COG1683	Conserved Protein
J6598_20010	COG1335	isochorismatase
J6598_20020	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
J6598_20025	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
J6598_20035	COG3084	Protein conserved in bacteria
J6598_20040	COG5001	Diguanylate cyclase
J6598_20040	COG4251	negative regulation of phosphorylation
J6598_20040	COG3706	GGDEF domain
J6598_20040	COG2203	Gaf domain
J6598_20055	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
J6598_20060	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
J6598_20065	COG1561	YicC-like family, N-terminal region
J6598_20100	COG1715	Restriction endonuclease
J6598_20110	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
J6598_20135	COG0583	DNA-binding transcription factor activity
J6598_20155	COG1262	PFAM Formylglycine-generating sulfatase enzyme
J6598_20160	COG0385	Bile acid
J6598_20165	COG0531	amino acid
J6598_20170	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
J6598_20175	COG0531	amino acid
J6598_20180	COG2731	YhcH YjgK YiaL family protein
J6598_20185	COG3250	beta-galactosidase activity
J6598_20190	COG1609	Transcriptional regulator
J6598_20230	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
J6598_20235	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
J6598_20235	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
J6598_20240	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
J6598_20245	COG3074	FtsZ-dependent cytokinesis
J6598_20255	COG1045	serine acetyltransferase
J6598_20265	COG0745	RESPONSE REGULATOR receiver
J6598_20270	COG2205	protein histidine kinase activity
J6598_20275	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
J6598_20280	COG0534	Mate efflux family protein
J6598_20295	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
J6598_20300	COG2937	Belongs to the GPAT DAPAT family
J6598_20305	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
J6598_20310	COG3161	chorismate lyase activity
J6598_20330	COG0604	alcohol dehydrogenase
J6598_20335	COG1519	Transferase
J6598_20340	COG0859	PFAM glycosyl transferase family 9
J6598_20345	COG0463	Glycosyl transferase, family 2
J6598_20350	COG0859	PFAM glycosyl transferase family 9
J6598_20355	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
J6598_20360	COG2990	Protein conserved in bacteria
J6598_20365	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
J6598_20375	COG0267	Belongs to the bacterial ribosomal protein bL33 family
J6598_20380	COG0227	Belongs to the bacterial ribosomal protein bL28 family
J6598_20385	COG2003	Belongs to the UPF0758 family
J6598_20390	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
J6598_20395	COG0756	dUTP diphosphatase activity
J6598_20400	COG1309	transcriptional regulator
J6598_20405	COG0668	transmembrane transport
J6598_20410	COG0166	Belongs to the GPI family
J6598_20415	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
J6598_20435	COG0045	succinate-CoA ligase (ADP-forming) activity
J6598_20435	COG1042	CoA-binding domain protein
J6598_20435	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
J6598_20465	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
J6598_20470	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
J6598_20475	COG1739	Uncharacterized protein family UPF0029
J6598_20480	COG0006	proline dipeptidase activity
J6598_20485	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
J6598_20490	COG1250	3-hydroxyacyl-CoA dehydrogenase
J6598_20490	COG1024	Enoyl-CoA hydratase
J6598_20495	COG0183	Belongs to the thiolase family
J6598_20520	COG0425	Belongs to the sulfur carrier protein TusA family
J6598_20525	COG0251	oxidation-reduction process
J6598_20530	COG2885	chlorophyll binding
J6598_20535	COG2818	Glycosylase
J6598_20540	COG0752	glycyl-tRNA synthetase alpha subunit
J6598_20545	COG0751	glycine-tRNA ligase activity
J6598_20585	COG1609	Transcriptional regulator
J6598_20615	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
J6598_20630	COG2960	long-chain fatty acid transporting porin activity
J6598_20635	COG5001	Diguanylate cyclase
J6598_20645	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
J6598_20660	COG3118	belongs to the thioredoxin family
J6598_20665	COG0513	Belongs to the DEAD box helicase family
J6598_20670	COG0248	Ppx GppA phosphatase
J6598_20680	COG0742	ribosomal rna small subunit methyltransferase
J6598_20695	COG3469	chitinase activity
J6598_20710	COG0805	protein transport
J6598_20715	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
J6598_20720	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
J6598_20725	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
J6598_20730	COG3165	ubiquinone biosynthetic process from chorismate
J6598_20735	COG2226	methyltransferase
J6598_20740	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
J6598_20745	COG0402	S-adenosylhomocysteine deaminase activity
J6598_20750	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
J6598_20785	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
J6598_20790	COG0848	biopolymer transport protein
J6598_20795	COG0811	peptide transport
J6598_20800	COG0811	peptide transport
J6598_20810	COG2771	luxR family
J6598_20815	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
J6598_20820	COG1349	DNA-binding transcription factor activity
J6598_20825	COG0745	RESPONSE REGULATOR receiver
J6598_20830	COG2205	protein histidine kinase activity
J6598_20840	COG4452	Inner membrane protein CreD
J6598_20845	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
J6598_20850	COG0355	proton-transporting ATP synthase activity, rotational mechanism
J6598_20855	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
J6598_20860	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
J6598_20865	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
J6598_20870	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
J6598_20875	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
J6598_20885	COG0356	it plays a direct role in the translocation of protons across the membrane
J6598_20895	COG1475	DNA binding
J6598_20900	COG1192	Involved in chromosome partitioning
J6598_20905	COG0357	Ribosomal RNA small subunit methyltransferase G
J6598_20910	COG0445	tRNA wobble uridine modification
J6598_20915	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
J6598_20925	COG4615	Cyclic peptide transporter
J6598_20930	COG1120	ATPase activity
J6598_20935	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
J6598_20940	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
J6598_20945	COG3550	peptidyl-serine autophosphorylation
J6598_20965	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
J6598_20970	COG3041	Addiction module toxin RelE StbE family
J6598_21095	COG1479	Protein of unknown function DUF262
J6598_21115	COG4974	Belongs to the 'phage' integrase family
J6598_21120	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
J6598_21125	COG0706	membrane insertase activity
J6598_21130	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
J6598_21135	COG0594	ribonuclease P activity
J6598_21140	COG0230	Belongs to the bacterial ribosomal protein bL34 family
J6598_21145	COG1126	abc transporter atp-binding protein