locus-tag	class	description
GRF56_00105	ENOG4108K5H	permease YjgP YjgQ family protein
GRF56_00110	ENOG4108M8S	permease YjgP YjgQ family protein
GRF56_00115	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
GRF56_00120	ENOG4105MYG	DNA polymerase iii, chi subunit
GRF56_00145	ENOG4108RTV	Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol (By similarity)
GRF56_00150	ENOG4105CH6	catalase
GRF56_00170	ENOG4108UDW	Transcriptional regulator, luxr family
GRF56_00175	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
GRF56_00180	ENOG4107IFA	Lipase (EC 3.1.1.3)
GRF56_00200	ENOG4105C1X	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity (By similarity)
GRF56_00205	ENOG4105KNR	Activates the small RNA gene sgrS under glucose- phosphate stress conditions as well as yfdZ. Represses its own transcription under both stress and non-stress conditions. Might act as a sensor of the intracellular accumulation of phosphoglucose by binding these molecules in its C-terminal solute-binding domain (By similarity)
GRF56_00215	ENOG4108IQK	o-acetylhomoserine
GRF56_00245	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
GRF56_00255	ENOG4105E4X	binding-protein-dependent transport systems inner membrane Component
GRF56_00285	ENOG4105BZU	Histidine kinase
GRF56_00300	ENOG4107QYX	exodeoxyribonuclease v alpha
GRF56_00305	ENOG4107QKA	exodeoxyribonuclease V beta
GRF56_00310	ENOG4105DSY	exodeoxyribonuclease V, gamma
GRF56_00315	ENOG4108VBZ	doxx family
GRF56_00320	ENOG4105C2I	pirin domain protein
GRF56_00330	ENOG4105CWB	LysR family transcriptional Regulator
GRF56_00350	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
GRF56_00355	ENOG4105E0F	Histidine kinase
GRF56_00365	ENOG4105D05	Receptor
GRF56_00405	ENOG4108ZT0	50S ribosomal protein l17
GRF56_00410	ENOG4105CTF	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
GRF56_00415	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
GRF56_00420	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
GRF56_00425	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
GRF56_00430	ENOG41067V7	50S ribosomal protein L36
GRF56_00435	ENOG4105CGG	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity)
GRF56_00440	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
GRF56_00445	ENOG4105VPB	50S ribosomal protein L30
GRF56_00450	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
GRF56_00455	ENOG4105K4C	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity)
GRF56_00460	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
GRF56_00465	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
GRF56_00470	ENOG4105VBI	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
GRF56_00475	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
GRF56_00480	ENOG4105KAR	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity)
GRF56_00485	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
GRF56_00490	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
GRF56_00495	ENOG41083MP	50s ribosomal protein l29
GRF56_00500	ENOG4108R70	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity)
GRF56_00505	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
GRF56_00510	ENOG4105KAP	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity)
GRF56_00515	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
GRF56_00520	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
GRF56_00525	ENOG41080KG	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
GRF56_00530	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
GRF56_00535	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
GRF56_00540	ENOG4108Z10	Involved in the binding of tRNA to the ribosomes (By similarity)
GRF56_00550	ENOG4105E0F	Histidine kinase
GRF56_00555	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
GRF56_00560	ENOG4108RRZ	Transcription elongation factor GreB
GRF56_00565	ENOG4105BZM	domain protein
GRF56_00585	ENOG4105D3C	The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters (By similarity)
GRF56_00590	ENOG4105MJ2	Competence protein
GRF56_00595	ENOG4107RUK	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins (By similarity)
GRF56_00600	ENOG4105CSF	NADPH-dependent glycerol-3-phosphate dehydrogenase
GRF56_00605	ENOG4105IX2	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA (By similarity)
GRF56_00610	ENOG4107YZP	Rhodanese domain protein
GRF56_00615	ENOG4105CJI	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
GRF56_00620	ENOG41063SB	peptidase
GRF56_00630	ENOG4105DIQ	Transcriptional regulator
GRF56_00645	ENOG4108UHU	Aldolase
GRF56_00650	ENOG4105C01	Dihydroxy-acid dehydratase
GRF56_00655	ENOG4108Z67	carbohydrate kinase, thermoresistant glucokinase family
GRF56_00660	ENOG4105C6Z	Gluconate
GRF56_00665	ENOG4105JIM	Phosphatidylserine synthase
GRF56_00670	ENOG4105CB5	ATP-dependent DNA helicase recG
GRF56_00680	ENOG4105SUU	thioesterase domain
GRF56_00685	ENOG4105CCX	Catalyzes the production of spermidine from putrescine and decarboxylated S-adenosylmethionine (dcSAM), which serves as an aminopropyl donor (By similarity)
GRF56_00690	ENOG4108YYA	Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine (By similarity)
GRF56_00695	ENOG4107S2Z	UPF0761 membrane protein
GRF56_00700	ENOG4105C6K	Malic enzyme
GRF56_00705	ENOG4105CIC	tryptophan-specific transport protein
GRF56_00710	ENOG4105CGD	Nad-dependent epimerase dehydratase
GRF56_00720	ENOG4105C25	Primosomal protein n'
GRF56_00725	ENOG4105VFB	Binds the 23S rRNA (By similarity)
GRF56_00735	ENOG4108NVR	Methyl-accepting chemotaxis
GRF56_00740	ENOG4108YYX	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. Modulates RNA-binding and helicase activities of the degradosome (By similarity)
GRF56_00745	ENOG4105EX9	Membrane
GRF56_00755	ENOG4105CNG	UPF0061 protein
GRF56_00760	ENOG4105N7H	Cytochrome
GRF56_00765	ENOG4105C9U	ATP-dependent DNA helicase RecQ
GRF56_00770	ENOG4108VUY	thioesterase Superfamily protein
GRF56_00785	ENOG4108RPX	mosc domain containing protein
GRF56_00790	ENOG4105D38	putrescine abc transporter
GRF56_00795	ENOG4105F38	ABC transporter, permease
GRF56_00800	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
GRF56_00805	ENOG4108HM4	ABC transporter
GRF56_00815	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
GRF56_00820	ENOG4105CFQ	glutamine synthetase
GRF56_00825	ENOG4108V7X	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
GRF56_00840	ENOG4108RH0	Crea protein
GRF56_00845	ENOG4105C5I	Dehydrogenase
GRF56_00850	ENOG4105R8A	Heat shock protein
GRF56_00865	ENOG4107R28	alpha amylase, catalytic region
GRF56_00880	ENOG4107R9T	Catalyzes the formation of 5-methyl-uridine at position 54 (m5U54) in all tRNAs (By similarity)
GRF56_00885	ENOG4105C8Q	Methyl-accepting chemotaxis
GRF56_00890	ENOG4108HWV	)-transporter
GRF56_00895	ENOG4105C2J	ABC transporter
GRF56_00905	ENOG4105CNT	hydrolase family 2
GRF56_00910	ENOG41060NJ	transcriptional regulator
GRF56_00915	ENOG4105CMR	udp-glucose 4-epimerase
GRF56_00920	ENOG4105F0Z	galactose-1-phosphate uridylyltransferase
GRF56_00925	ENOG4105CRD	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P) (By similarity)
GRF56_00930	ENOG4105ENN	converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose (By similarity)
GRF56_00935	ENOG4105DWR	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity)
GRF56_00945	ENOG4105K6V	RNA polymerase
GRF56_00955	ENOG4105C75	arginyL-tRNA synthetase
GRF56_00965	ENOG4108R5P	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery (By similarity)
GRF56_00970	ENOG4105C4N	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis (By similarity)
GRF56_00980	ENOG4105D0S	secretion protein (HlyD
GRF56_00985	ENOG4105CJ1	ABC, transporter
GRF56_00990	ENOG4107QWP	ABC-2 type transporter
GRF56_00995	ENOG4107QWP	ABC-2 type transporter
GRF56_01000	ENOG4107QZF	nitrite reductase NADPH large subunit
GRF56_01005	ENOG4105WZK	nitrite reductase NADPH small subunit
GRF56_01010	ENOG4107V9H	nitrite transporter
GRF56_01015	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
GRF56_01020	ENOG4105CJW	magnesium transporter
GRF56_01030	ENOG4105CGH	5'-nucleotidase
GRF56_01040	ENOG4105UIB	(ABC) transporter
GRF56_01045	ENOG4108JQ9	ABC transporter
GRF56_01050	ENOG4105DIH	basic membrane
GRF56_01065	ENOG4105C4R	Atp-dependent dna helicase
GRF56_01070	ENOG4108K0D	peptidase, M48
GRF56_01095	ENOG41061EV	selenium-binding protein YdfZ
GRF56_01155	ENOG4105PF3	O-Antigen polymerase
GRF56_01165	ENOG4105CUI	Catalyzes the interconversion between ADP-D-glycero- beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose (By similarity)
GRF56_01170	ENOG41062JF	Transcriptional regulator
GRF56_01175	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
GRF56_01180	ENOG4105CPQ	Dehydrogenase
GRF56_01185	ENOG4105MPD	Cytochrome
GRF56_01190	ENOG4105BZU	Histidine kinase
GRF56_01195	ENOG4105C4R	Atp-dependent dna helicase
GRF56_01200	ENOG4105C9B	Cysteine desulfurase
GRF56_01205	ENOG4105P9C	Participates in cysteine desulfuration mediated by SufS. Cysteine desulfuration mobilizes sulfur from L-cysteine to yield L-alanine and constitutes an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules. Functions as a sulfur acceptor for SufS, by mediating the direct transfer of the sulfur atom from the S-sulfanylcysteine of SufS, an intermediate product of cysteine desulfuration process (By similarity)
GRF56_01210	ENOG4105CUZ	uba thif-type nad fad binding protein
GRF56_01240	ENOG4105F03	Provides the (R)-glutamate required for cell wall biosynthesis (By similarity)
GRF56_01250	ENOG41063Z6	transcriptional regulator, lysR family
GRF56_01265	ENOG4108UM6	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity)
GRF56_01270	ENOG4105CY8	phosphoribosylaminoimidazole carboxylase atpase subunit
GRF56_01275	ENOG4105FCD	Major Facilitator
GRF56_01280	ENOG4105DY9	regulatoR
GRF56_01285	ENOG4108HRK	Histidine kinase
GRF56_01290	ENOG4105CBX	hi0933 family
GRF56_01295	ENOG41090A1	ferritin
GRF56_01300	ENOG4105RKW	reductase (By
GRF56_01305	ENOG4108M6U	Universal stress protein A
GRF56_01335	ENOG4105EMK	carboxylate amino acid amine transporter
GRF56_01345	ENOG4108W7E	Catalyzes the ATP-dependent phosphorylation of the 3- deoxy-D-manno-octulosonic acid (Kdo) residue in Kdo-lipid IV(A) at the 4-OH position (By similarity)
GRF56_01350	ENOG4105DKP	glycosyl transferase, family 9
GRF56_01360	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
GRF56_01365	ENOG4105VFG	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity)
GRF56_01370	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
GRF56_01375	ENOG4105FE8	tRNA (Guanosine-2'-O-)-methyltransferase
GRF56_01380	ENOG4105EQK	-acetyltransferase
GRF56_01385	ENOG4108EUD	Lysophospholipase
GRF56_01390	ENOG4105DQF	Hydrolase
GRF56_01420	ENOG4105Y7M	Transcriptional regulator, TetR family
GRF56_01425	ENOG410624X	efflux transporter, rnd family, mfp subunit
GRF56_01430	ENOG4105BZS	acriflavin resistance protein
GRF56_01435	ENOG4105BZU	Histidine kinase
GRF56_01440	ENOG4105DC8	reductase
GRF56_01450	ENOG4105D9K	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity)
GRF56_01455	ENOG4105C8X	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity)
GRF56_01465	ENOG4105C08	Histidine kinase
GRF56_01470	ENOG4105EEX	Two component transcriptional regulator (Winged helix family
GRF56_01475	ENOG4105C2C	drug resistance transporter, Bcr CflA
GRF56_01490	ENOG4105JKW	Valine--pyruvate aminotransferase
GRF56_01495	ENOG4108ZNX	Heat shock protein
GRF56_01500	ENOG4108ZNX	Heat shock protein
GRF56_01510	ENOG4105ECQ	AraC Family Transcriptional Regulator
GRF56_01515	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
GRF56_01520	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
GRF56_01525	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
GRF56_01530	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
GRF56_01535	ENOG4105EAB	amino acid AbC transporter
GRF56_01540	ENOG4105E5Q	amino acid AbC transporter
GRF56_01545	ENOG4105CDA	abc transporter atp-binding protein
GRF56_01550	ENOG4105VG0	50S ribosomal protein l34
GRF56_01555	ENOG4105NVJ	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme (By similarity)
GRF56_01560	ENOG4105VAS	Could be involved in insertion of integral membrane proteins into the membrane (By similarity)
GRF56_01565	ENOG4105DHW	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
GRF56_01570	ENOG4105C1H	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity)
GRF56_01575	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
GRF56_01645	ENOG4107RHT	methyl-accepting chemotaxis sensory transducer with Pas Pac sensor
GRF56_01680	ENOG4108KTG	Membrane protein, drug metabolite transporter
GRF56_01720	ENOG4108F3G	Type I restriction-modification system, R subunit
GRF56_01740	ENOG4105CAF	HipA N-terminal domain protein
GRF56_01745	ENOG4105S6R	Iron-hydroxamate transporter permease subunit
GRF56_01750	ENOG4105J76	Periplasmic binding protein
GRF56_01755	ENOG4105E0A	ABC, transporter
GRF56_01760	ENOG4105IBP	Cyclic peptide transporter
GRF56_01770	ENOG4105QTB	Flavodoxin
GRF56_01775	ENOG4107RE5	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity)
GRF56_01780	ENOG4105D28	Specifically methylates the N7 position of a guanine in 16S rRNA (By similarity)
GRF56_01785	ENOG4107QJE	Chromosome Partitioning Protein
GRF56_01790	ENOG4105FA0	parb-like partition protein
GRF56_01800	ENOG4105EE4	it plays a direct role in the translocation of protons across the membrane (By similarity)
GRF56_01805	ENOG4105KY6	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
GRF56_01810	ENOG4107Z6K	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
GRF56_01815	ENOG4107S15	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
GRF56_01820	ENOG4105CDG	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity)
GRF56_01825	ENOG4105J80	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity)
GRF56_01830	ENOG4105C4J	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity)
GRF56_01835	ENOG4105KNM	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
GRF56_01840	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
GRF56_01845	ENOG4105CT7	inner membrane cred family protein
GRF56_01860	ENOG4105EB3	Histidine kinase
GRF56_01865	ENOG4105E3W	Two component transcriptional regulator (Winged helix family
GRF56_01870	ENOG410804X	Transcriptional regulator
GRF56_01875	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
GRF56_01880	ENOG4105VJY	transcriptional regulator
GRF56_01900	ENOG4109015	Biopolymer transport protein exbD tolR
GRF56_01905	ENOG410822N	TonB family
GRF56_01940	ENOG4105DQW	permease for cytosine purines, uracil, thiamine, allantoin
GRF56_01945	ENOG4105DZC	cytosine deaminase
GRF56_01950	ENOG4105WMR	Protein CrcB homolog
GRF56_01955	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
GRF56_01960	ENOG4105JC1	sterol-binding domain protein
GRF56_01965	ENOG4105CNK	Required, probably indirectly, for the hydroxylation of 2-octaprenylphenol to 2-octaprenyl-6-hydroxy-phenol, the fourth step in ubiquinone biosynthesis (By similarity)
GRF56_01970	ENOG4105WKS	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity)
GRF56_01975	ENOG4105X8U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation (By similarity)
GRF56_01980	ENOG4105DCX	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity)
GRF56_01985	ENOG4105F8V	Hydrolase, tatD family
GRF56_01990	ENOG4105D52	delta-aminolevulinic acid dehydratase
GRF56_02000	ENOG4105E03	chitinase
GRF56_02005	ENOG4105DGW	oligopeptidase A
GRF56_02010	ENOG4105BZU	Histidine kinase
GRF56_02015	ENOG4105FFN	Specifically methylates the guanosine in position 1516 of 16S rRNA (By similarity)
GRF56_02025	ENOG4105C9X	ppx gppa phosphatase
GRF56_02030	ENOG4105C1J	atp-dependent rna helicase
GRF56_02035	ENOG4105K63	Thioredoxin
GRF56_02040	ENOG4105C4P	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity)
GRF56_02050	ENOG4105D3H	Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol (By similarity)
GRF56_02055	ENOG4107QK7	reductase
GRF56_02070	ENOG4105W0Z	cytoplasmic protein
GRF56_02085	ENOG4105M78	Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide (By similarity)
GRF56_02090	ENOG4108IV0	ABC, transporter
GRF56_02095	ENOG4105C0Z	ABC transporter
GRF56_02100	ENOG4105CF8	branched-chain amino acid ABC transporter, permease
GRF56_02105	ENOG4105C32	Amino acid ABC transporter (Permease)
GRF56_02110	ENOG4105CP9	extracellular ligand-binding receptor
GRF56_02115	ENOG4105ETE	Transcriptional regulator (LacI family
GRF56_02120	ENOG4105F8D	glycoside hydrolase family 4
GRF56_02125	ENOG4105CI1	PTS System
GRF56_02130	ENOG4105FDP	GntR family transcriptional regulator
GRF56_02135	ENOG4105C8Q	Methyl-accepting chemotaxis
GRF56_02150	ENOG41072JS	exoenzyme T
GRF56_02155	ENOG4105BZU	Histidine kinase
GRF56_02170	ENOG4105C38	Glycyl-tRNA synthetase beta subunit
GRF56_02175	ENOG4108HMW	glycyl-tRNA synthetase, alpha subunit
GRF56_02180	ENOG4108R3E	Dna-3-methyladenine glycosylase i
GRF56_02185	ENOG4108ZG0	Ompa motb domain protein
GRF56_02190	ENOG4105M4H	endoribonuclease L-psp
GRF56_02195	ENOG41082K8	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Interacts with IscS and stimulates its activity. Then, accepts a sulfur from IscS and transfers it in turn to TusD (By similarity)
GRF56_02210	ENOG4105E0F	Histidine kinase
GRF56_02215	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
GRF56_02220	ENOG4105CHU	acetyl-coa acetyltransferase
GRF56_02225	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
GRF56_02230	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
GRF56_02235	ENOG4105D9Y	Splits dipeptides with a prolyl residue in the C- terminal position (By similarity)
GRF56_02240	ENOG4108ZK7	protein family UPF0029, Impact, N-terminal protein
GRF56_02245	ENOG4105D37	Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA (By similarity)
GRF56_02250	ENOG4108RR8	protoporphyrinogen oxidase
GRF56_02285	ENOG4105CD5	CoA-binding domain protein
GRF56_02300	ENOG4105EMY	transcriptional regulator
GRF56_02305	ENOG4105C6M	Alpha-keto-beta-hydroxylacyl reductoisomerase
GRF56_02310	ENOG4107QP8	phosphohexose isomerase
GRF56_02315	ENOG4105D64	Mechanosensitive ion channel
GRF56_02320	ENOG4105EC0	Required for nucleoid occlusion (NO) phenomenon, which prevents Z-ring formation and cell division over the nucleoid. Acts as a DNA-associated cell division inhibitor that binds simultaneously chromosomal DNA and FtsZ, and disrupts the assembly of FtsZ polymers. SlmA-DNA-binding sequences (SBS) are dispersed on non-Ter regions of the chromosome, preventing FtsZ polymerization at these regions (By similarity)
GRF56_02325	ENOG4108Z1K	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA (By similarity)
GRF56_02330	ENOG4105CJS	Phosphopantothenoylcysteine decarboxylase
GRF56_02335	ENOG4105W5Q	DNA repair protein (RadC
GRF56_02340	ENOG4105KDC	50s ribosomal protein l28
GRF56_02345	ENOG4105W0E	50S ribosomal protein L33
GRF56_02355	ENOG4105ERD	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity)
GRF56_02360	ENOG4108MJ5	VirK protein
GRF56_02365	ENOG4108ZEF	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity)
GRF56_02370	ENOG4105M5K	heptosyltransferase
GRF56_02375	ENOG4106WTF	Glycosyl transferase, family 2
GRF56_02380	ENOG4105XA0	heptosyltransferase ii
GRF56_02385	ENOG4105D8A	3-Deoxy-D-manno-octulosonic-acid transferase
GRF56_02400	ENOG4106ETB	IIa component
GRF56_02405	ENOG4105DIQ	Transcriptional regulator
GRF56_02410	ENOG4105D3Z	quinone oxidoreductase, yhdh yhfp family
GRF56_02440	ENOG4105VEI	Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4- hydroxybenzoate (4HB) for the ubiquinone pathway (By similarity)
GRF56_02445	ENOG4105C4G	Synthesis of 3-octaprenyl-4-hydroxybenzoate (By similarity)
GRF56_02450	ENOG4105E55	glycerol-3-phosphate acyltransferase
GRF56_02455	ENOG4105DS7	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity)
GRF56_02470	ENOG4107R73	Mate efflux family protein
GRF56_02475	ENOG4108UIQ	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity)
GRF56_02480	ENOG4105E0F	Histidine kinase
GRF56_02485	ENOG4105E3W	Two component transcriptional regulator (Winged helix family
GRF56_02495	ENOG4105D7W	serine acetyltransferase
GRF56_02505	ENOG41065UX	Non-essential, abundant cell division factor that is required for proper Z-ring formation. It is recruited early to the divisome by direct interaction with FtsZ, stimulating Z-ring assembly and thereby promoting cell division earlier in the cell cycle. Its recruitment to the Z-ring requires functional FtsA or ZipA (By similarity)
GRF56_02510	ENOG4108556	Isoprenoid biosynthesis protein with amidotransferase-like domain
GRF56_02515	ENOG4105C2M	dna polymerase I
GRF56_02520	ENOG4108Z0R	Transferase
GRF56_02555	ENOG4105CQ4	Transcriptional regulator
GRF56_02560	ENOG4105CNT	hydrolase family 2
GRF56_02565	ENOG4105FK9	beta-D-galactosidase beta subunit
GRF56_02570	ENOG4105E5D	amino acid
GRF56_02575	ENOG4108Y51	tRNA-binding protein
GRF56_02580	ENOG4105E5D	amino acid
GRF56_02585	ENOG4105DHU	Bile acid
GRF56_02600	ENOG4105C4W	S-formylglutathione hydrolase
GRF56_02610	ENOG4105CC0	LysR family Transcriptional regulator
GRF56_02615	ENOG4105DSJ	YicC domain protein
GRF56_02620	ENOG4105ED0	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates (By similarity)
GRF56_02625	ENOG4107QP2	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
GRF56_02635	ENOG4108Z6Z	Transcriptional regulator
GRF56_02645	ENOG4105PC1	Conserved Protein
GRF56_02655	ENOG4105E27	serine threonine protein kinase
GRF56_02660	ENOG4108Z33	Thiol disulfide Interchange Protein
GRF56_02665	ENOG4107RH7	Nicotinate phosphoribosyltransferase
GRF56_02670	ENOG4108RWI	nicotinamidase
GRF56_02680	ENOG4105EWC	Purine nucleoside phosphorylase
GRF56_02685	ENOG4106HNH	Acyl-transferase
GRF56_02690	ENOG4106HNH	Acyl-transferase
GRF56_02695	ENOG4105C0P	Mg chelatase subunit ChlI
GRF56_02710	ENOG4105P3Y	Acetolactate synthase 2 regulatory subunit
GRF56_02715	ENOG4105CM2	brancheD-chain amino acid aminotransferase
GRF56_02720	ENOG4105C01	Dihydroxy-acid dehydratase
GRF56_02725	ENOG4105C7B	Threonine dehydratase
GRF56_02735	ENOG4105KBX	Transcriptional regulator, TetR family
GRF56_02740	ENOG4105UYK	outer membrane protein a
GRF56_02745	ENOG4105CUC	YeeE YedE family protein
GRF56_02750	ENOG4108N3W	hemolysin secretion protein
GRF56_02755	ENOG4105FR1	rard protein
GRF56_02765	ENOG4105C26	Dehydrogenase
GRF56_02770	ENOG4108JCI	Transcriptional regulator
GRF56_02780	ENOG4105C26	Dehydrogenase
GRF56_02785	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
GRF56_02790	ENOG4107R11	Transcriptional regulator
GRF56_02795	ENOG4108TFM	Kinase, PfkB family
GRF56_02815	ENOG4105CGY	Dna recombination protein
GRF56_02820	ENOG4105EKD	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism (By similarity)
GRF56_02825	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
GRF56_02830	ENOG4105CUX	Signal transduction histidine kinase
GRF56_02840	ENOG4105C5F	glutamine synthetase
GRF56_02850	ENOG4105D37	Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA (By similarity)
GRF56_02855	ENOG4105C1A	potassium transporter peripheral membrane
GRF56_02860	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
GRF56_02865	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
GRF56_02870	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
GRF56_02875	ENOG4108WZM	domain protein
GRF56_02880	ENOG4105C79	DNA protecting protein DprA
GRF56_02885	ENOG4108RPN	Protein smg homolog
GRF56_02890	ENOG4108WI1	Dna topoisomerase
GRF56_02900	ENOG4105EK0	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
GRF56_02905	ENOG4105DBS	Key enzyme in heme biosynthesis. Catalyzes the oxidative decarboxylation of propionic acid side chains of rings A and B of coproporphyrinogen III (By similarity)
GRF56_02910	ENOG4105E2X	shikimate dehydrogenase
GRF56_02920	ENOG4105WHM	Necessary for normal cell division and for the maintenance of normal septation (By similarity)
GRF56_02925	ENOG4106RE7	Cytochrome
GRF56_02930	ENOG4105ZR3	A GTPase-activating protein (GAP) that modifies Der EngA GTPase function. May play a role in ribosome biogenesis (By similarity)
GRF56_02935	ENOG4105XCT	Protein of unknown function (DUF2489)
GRF56_02940	ENOG4105D4P	Coproporphyrinogen iii oxidase
GRF56_02960	ENOG4105C5B	carbamate kinase
GRF56_02965	ENOG4105DBV	ornithine carbamoyltransferase
GRF56_02970	ENOG4105CSX	c4-dicarboxylate anaerobic carrier
GRF56_02975	ENOG410682Y	Regulates arginine biosynthesis genes (By similarity)
GRF56_02980	ENOG4108R9M	Involved in allosteric regulation of aspartate carbamoyltransferase (By similarity)
GRF56_02985	ENOG4105CXT	aspartate transcarbamylase
GRF56_03005	ENOG4105DUM	transcriptional regulator, lysR family
GRF56_03015	ENOG4105C8Q	Methyl-accepting chemotaxis
GRF56_03025	ENOG4105CF7	AraC family transcriptional regulator
GRF56_03030	ENOG4108I6A	alcohol dehydrogenase
GRF56_03035	ENOG4108IIE	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
GRF56_03040	ENOG4105C15	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
GRF56_03050	ENOG4105WWK	YheO domain protein
GRF56_03055	ENOG4105CEM	UPF0597 protein
GRF56_03065	ENOG4107QMW	pyridine nucleotide-disulfide oxidoreductase
GRF56_03070	ENOG4106SNF	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
GRF56_03075	ENOG4105C34	Pseudouridine synthase
GRF56_03080	ENOG4105DBW	Multi-copper polyphenol oxidoreductase laccase
GRF56_03085	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
GRF56_03095	ENOG4105CU9	asparagine synthetase A
GRF56_03100	ENOG4108VVK	transcriptional Regulator, AsnC
GRF56_03115	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
GRF56_03120	ENOG410642E	Short chain dehydrogenase
GRF56_03135	ENOG4107WP9	Histidine kinase
GRF56_03145	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
GRF56_03150	ENOG4108UQ5	membrane protein YcdZ
GRF56_03180	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
GRF56_03185	ENOG4105IFJ	Histidine kinase
GRF56_03195	ENOG4107QY8	reductase
GRF56_03200	ENOG4105CUW	cytochrome C-TYPE protein
GRF56_03205	ENOG4105BZU	Histidine kinase
GRF56_03215	ENOG4108IYH	Dna topoisomerase
GRF56_03240	ENOG4107ZYR	domain protein
GRF56_03245	ENOG4105D4A	Cell wall formation (By similarity)
GRF56_03250	ENOG4105HJX	Biotin- acetyl-CoA-carboxylase ligase
GRF56_03270	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
GRF56_03280	ENOG4105PM1	preprotein translocase subunit SecE
GRF56_03285	ENOG4105E5V	Participates in transcription elongation, termination and antitermination (By similarity)
GRF56_03290	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
GRF56_03295	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
GRF56_03300	ENOG4108VZM	50s ribosomal protein L10
GRF56_03305	ENOG4105KBC	Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity)
GRF56_03310	ENOG4108IIJ	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
GRF56_03315	ENOG4105D27	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
GRF56_03320	ENOG4105WWK	YheO domain protein
GRF56_03325	ENOG4105KME	endoribonuclease L-psp
GRF56_03330	ENOG4108ZAT	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE (By similarity)
GRF56_03335	ENOG4108ZKU	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions (By similarity)
GRF56_03340	ENOG4105YKK	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions (By similarity)
GRF56_03345	ENOG4108UKE	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity)
GRF56_03350	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
GRF56_03355	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
GRF56_03360	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
GRF56_03365	ENOG4108ZI0	d,d-heptose 1,7-bisphosphate phosphatase
GRF56_03400	ENOG4105EJ2	Transcriptional regulator
GRF56_03415	ENOG4107FS9	Membrane
GRF56_03430	ENOG4105JQN	Transcriptional regulator
GRF56_03445	ENOG4105VVZ	metal-binding protein
GRF56_03450	ENOG41076UM	multiple antibiotic resistance (MarC)-related protein
GRF56_03470	ENOG4105CHQ	Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella (By similarity)
GRF56_03475	ENOG4107RZC	phospholipase d
GRF56_03490	ENOG4105CUG	Oligopeptidase b
GRF56_03505	ENOG4105EMU	Dehydrogenase
GRF56_03510	ENOG4108W5M	transcriptional regulator
GRF56_03515	ENOG4108K2R	Glutathione-regulated potassium-efflux system ancillary protein
GRF56_03540	ENOG4106H78	methyltransferase
GRF56_03545	ENOG4105CCP	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
GRF56_03550	ENOG4105CAK	Cell division ATP-binding protein ftsE
GRF56_03555	ENOG4105CRP	Part of the ABC transporter FtsEX involved in
GRF56_03565	ENOG41077A9	carbonic anhydrase
GRF56_03570	ENOG4105CZE	histidine utilization repressor
GRF56_03575	ENOG4105CI2	imidazolone-5-propionate hydrolase
GRF56_03580	ENOG41088SP	formiminoglutamate hydrolase
GRF56_03585	ENOG4105CGP	Urocanate hydratase
GRF56_03590	ENOG4105C84	Histidine ammonia-lyase
GRF56_03595	ENOG4105EWV	Sodium calcium exchanger membrane region
GRF56_03600	ENOG4105CXC	rtn protein
GRF56_03605	ENOG41062P1	Diguanylate cyclase phosphodiesterase
GRF56_03635	ENOG4105GVR	general secretion pathway protein D
GRF56_03650	ENOG4107QHF	type ii secretion system protein e
GRF56_03655	ENOG4105D7Q	type ii secretion system
GRF56_03675	ENOG4106855	Competence protein
GRF56_03700	ENOG4105DFF	Rod shape-determining protein mreb
GRF56_03705	ENOG4105N3I	Involved in formation and maintenance of cell shape (By similarity)
GRF56_03710	ENOG4105VQ7	Rod shape-determining protein MreD
GRF56_03715	ENOG4108Z03	MAF-like protein
GRF56_03720	ENOG4105C03	ribonuclease
GRF56_03725	ENOG4105QD6	exported protein
GRF56_03740	ENOG4105D1U	peptidase U62 modulator of DNA gyrase
GRF56_03755	ENOG4105CSH	Transporter
GRF56_03790	ENOG4105EEQ	Na H antiporter
GRF56_03795	ENOG4105C3R	Methionine synthase
GRF56_03800	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
GRF56_03810	ENOG4105ETX	regulatoR
GRF56_03830	ENOG4105CBF	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction (By similarity)
GRF56_03835	ENOG4108UV6	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity)
GRF56_03840	ENOG4105D06	uba thif-type nad fad binding protein
GRF56_03850	ENOG4105CA8	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity)
GRF56_03855	ENOG4105D41	biosynthesis protein thiH
GRF56_03875	ENOG4105EQK	-acetyltransferase
GRF56_03885	ENOG4105BZU	Histidine kinase
GRF56_03890	ENOG4105C44	Serine transporter
GRF56_03895	ENOG4105CH7	arginosuccinase
GRF56_03900	ENOG4105CDH	Citrulline--aspartate ligase
GRF56_03910	ENOG4105CAS	nag kinase
GRF56_03915	ENOG4105C0N	N-acetylglutamate semialdehyde dehydrogenase
GRF56_03925	ENOG4105CCA	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle (By similarity)
GRF56_03935	ENOG4108Z66	YbaK ebsC protein
GRF56_03955	ENOG4105CMU	LysR family (Transcriptional regulator
GRF56_03965	ENOG41067MG	lrgb family
GRF56_03975	ENOG4108NRW	Phospholipase, patatin family
GRF56_03980	ENOG4105D86	that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity)
GRF56_03985	ENOG4107TH8	cina domain protein
GRF56_03990	ENOG4105C68	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity)
GRF56_04000	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
GRF56_04005	ENOG4105CFH	Aspartokinase
GRF56_04010	ENOG4105VM8	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding (By similarity)
GRF56_04045	ENOG41061WM	D-Alanyl-D-Alanine
GRF56_04050	ENOG4106W5V	Membrane
GRF56_04065	ENOG4105HDK	L-asparaginase
GRF56_04080	ENOG4105D4X	repressor
GRF56_04085	ENOG4105C5Y	PTS System
GRF56_04090	ENOG4105CG3	alpha amylase, catalytic region
GRF56_04095	ENOG4108UW5	maltose o-acetyltransferase
GRF56_04105	ENOG4105D3G	Pseudouridine synthase
GRF56_04110	ENOG4105BZK	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair (By similarity)
GRF56_04135	ENOG4105DFP	Integrase
GRF56_04140	ENOG4105D70	Integrase catalytic subunit
GRF56_04145	ENOG4105F5W	AtP-binding protein
GRF56_04150	ENOG4107VGF	ig domain protein group 2 domain protein
GRF56_04155	ENOG4105BZU	Histidine kinase
GRF56_04175	ENOG4108P8R	
GRF56_04230	ENOG4108YGG	dna repair protein
GRF56_04270	ENOG4105FDP	GntR family transcriptional regulator
GRF56_04275	ENOG4108KD5	ADP-ribosylation crystallin J1
GRF56_04285	ENOG4108TFM	Kinase, PfkB family
GRF56_04295	ENOG4105MAW	Antitoxin component of a toxin-antitoxin (TA) module. Labile antitoxin that counteracts the effect of the CbtA (YeeV) toxin. It does not bind to the cognate toxin but instead binds to MreB and FtsZ (the toxin targets), enhancing their polymerization by forming higher-order bundles
GRF56_04315	ENOG4106RHG	Yeca family
GRF56_04325	ENOG4105DRC	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity)
GRF56_04340	ENOG4105CDM	Glutamate-1-semialdehyde aminotransferase
GRF56_04345	ENOG4105CMQ	Chloride channel
GRF56_04355	ENOG4108YX9	iron--sulfur cluster insertion protein erpA
GRF56_04360	ENOG4105DFD	Na H antiporter
GRF56_04400	ENOG4105CXW	Synthesizes alpha-1,4-glucan chains using ADP-glucose (By similarity)
GRF56_04405	ENOG4107QQ4	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans (By similarity)
GRF56_04410	ENOG4105D8J	Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle (By similarity)
GRF56_04415	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
GRF56_04430	ENOG4107IX6	phosphate transport regulator
GRF56_04435	ENOG4105CJ3	phosphate transporter
GRF56_04440	ENOG4105CFH	Aspartokinase
GRF56_04445	ENOG4105C28	cystathionine
GRF56_04450	ENOG4105GGQ	This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis (By similarity)
GRF56_04460	ENOG4108Z7R	Chaperone CsaA
GRF56_04465	ENOG4105C44	Serine transporter
GRF56_04470	ENOG4108RNI	3'(2')5'-bisphosphate nucleotidase
GRF56_04475	ENOG4107RK2	ADP-ribose diphosphatase NudE
GRF56_04480	ENOG4107Y3D	HAD-superfamily hydrolase subfamily IA variant 3
GRF56_04495	ENOG4108UW5	maltose o-acetyltransferase
GRF56_04500	ENOG4107PU6	Membrane
GRF56_04505	ENOG4105DE7	Sulfate ABC transporter periplasmic sulfate-binding protein
GRF56_04515	ENOG4108I5D	sulfate abc transporter
GRF56_04520	ENOG4105ECW	sulfate abc transporter
GRF56_04525	ENOG4108IJ6	ABC transporter
GRF56_04530	ENOG4107R11	Transcriptional regulator
GRF56_04535	ENOG4108IYI	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine (By similarity)
GRF56_04540	ENOG4105DRP	amino acid AbC transporter
GRF56_04550	ENOG4105CDA	abc transporter atp-binding protein
GRF56_04555	ENOG4105CT1	(ABC) transporter
GRF56_04560	ENOG4108M1A	Chitin-binding protein
GRF56_04565	ENOG4108N3W	hemolysin secretion protein
GRF56_04580	ENOG4108JA0	Oxidoreductase, FAD NAD(P)-binding domain protein
GRF56_04605	ENOG4105G0K	glycine radical enzyme YjjI family
GRF56_04610	ENOG41076CZ	activating enzyme
GRF56_04625	ENOG4105CGF	Aromatic amino acid aminotransferase
GRF56_04655	ENOG4108V1J	Has antioxidant activity. Could remove peroxides or H(2)O(2) (By similarity)
GRF56_04665	ENOG4105C1J	atp-dependent rna helicase
GRF56_04695	ENOG4105XTV	UPF0231 protein
GRF56_04700	ENOG4108IXP	Carbohydrate diacid transcriptional activator CdaR
GRF56_04705	ENOG4107QQ0	gntp family
GRF56_04710	ENOG4105BZW	Glycerate kinase
GRF56_04725	ENOG4105HEI	LysR family (Transcriptional regulator
GRF56_04730	ENOG4105D9N	nucleoside
GRF56_04740	ENOG4105VZ9	UPF0235 protein
GRF56_04745	ENOG4108VIA	integral membrane protein
GRF56_04750	ENOG4105II7	pyrroline-5-carboxylate reductase
GRF56_04755	ENOG4105DFA	alanine racemase domain protein
GRF56_04760	ENOG4105CZX	twitching motility protein
GRF56_04765	ENOG4105CZX	twitching motility protein
GRF56_04770	ENOG4105D1Q	UPF0246 protein
GRF56_04785	ENOG4108YZN	class I peptide chain release factor
GRF56_04790	ENOG4108YZA	Nitrogen regulatory protein pii
GRF56_04805	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
GRF56_04810	ENOG4105EZR	dyp-type peroxidase family protein
GRF56_04815	ENOG410682Y	Regulates arginine biosynthesis genes (By similarity)
GRF56_04820	ENOG4105E5Z	arginine transporter ATP-binding subunit
GRF56_04825	ENOG4106PMH	Extracellular solute-binding protein family 3
GRF56_04830	ENOG4105GBT	ABC transporter
GRF56_04835	ENOG4105DMR	ABC, transporter
GRF56_04840	ENOG4105C80	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
GRF56_04845	ENOG4108UV7	flagellar protein motX
GRF56_04850	ENOG4108EGH	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity)
GRF56_04860	ENOG4108JU6	CBS domain protein
GRF56_04865	ENOG4106KVJ	cytochrome C assembly protein
GRF56_04870	ENOG4105CB9	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
GRF56_04875	ENOG4105K5M	30s ribosomal protein S16
GRF56_04880	ENOG4108ZR6	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity)
GRF56_04885	ENOG4105D6X	Specifically methylates guanosine-37 in various tRNAs (By similarity)
GRF56_04890	ENOG4108YY1	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity)
GRF56_04905	ENOG4105IRT	Sequence-specific endonuclease that cleaves unmethylated GATC sequences. It is involved in DNA mismatch repair (By similarity)
GRF56_04910	ENOG4105EJF	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity)
GRF56_04915	ENOG4108HRM	phosphoenolpyruvate--protein phosphotransferase
GRF56_04920	ENOG4105C3B	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity)
GRF56_04925	ENOG4105C0V	Provides the sole de novo source of dTMP for DNA biosynthesis (By similarity)
GRF56_04930	ENOG4105DRC	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity)
GRF56_04940	ENOG41063Z6	transcriptional regulator, lysR family
GRF56_04945	ENOG41080HT	Transcriptional regulator, arsr family
GRF56_04950	ENOG4105KQV	Binds directly to 16S ribosomal RNA (By similarity)
GRF56_04955	ENOG4105CJR	Integral membrane protein (MviN
GRF56_04960	ENOG4105DTN	riboflavin biosynthesis protein ribF
GRF56_04965	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
GRF56_04970	ENOG4105M02	This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity)
GRF56_04975	ENOG41090X3	Peptidyl-prolyl cis-trans isomerase
GRF56_04980	ENOG4105C48	Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) (By similarity)
GRF56_05040	ENOG4105C4K	Nad synthetase
GRF56_05045	ENOG4108YZA	Nitrogen regulatory protein pii
GRF56_05055	ENOG4106762	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD) (By similarity)
GRF56_05065	ENOG4105X0D	Fimbrial protein
GRF56_05070	ENOG4105EYA	deoxyribonuclease
GRF56_05075	ENOG4105D9N	nucleoside
GRF56_05085	ENOG4105FCI	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate (By similarity)
GRF56_05090	ENOG4105CMW	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis (By similarity)
GRF56_05095	ENOG4105CZG	Phosphotransfer between the C1 and C5 carbon atoms of pentose (By similarity)
GRF56_05100	ENOG4105D3A	purine nucleoside phosphorylase DeoD-type
GRF56_05110	ENOG4105EAC	phosphoserine phosphatase
GRF56_05125	ENOG4105DNJ	May play a role in the repair of endogenous alkylation damage (By similarity)
GRF56_05135	ENOG4105PBF	Anti-RNA polymerase sigma 70 factor
GRF56_05140	ENOG4105K70	DNA-binding protein
GRF56_05150	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
GRF56_05155	ENOG4105C56	H( )-stimulated, divalent metal cation uptake system (By similarity)
GRF56_05160	ENOG4108ZDX	Binds together with S18 to 16S ribosomal RNA (By similarity)
GRF56_05165	ENOG4105VH8	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity)
GRF56_05170	ENOG4105K9Q	Binds to the 23S rRNA (By similarity)
GRF56_05175	ENOG4105DP0	ferredoxin-NADP reductase
GRF56_05200	ENOG4105DQ4	alcohol dehydrogenase
GRF56_05205	ENOG4105W39	Membrane
GRF56_05215	ENOG4105D9M	gamma-glutamylcysteine synthetase
GRF56_05220	ENOG4108IQE	Amp-dependent synthetase and ligase
GRF56_05230	ENOG4108RTV	Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol (By similarity)
GRF56_05250	ENOG4105BZU	Histidine kinase
GRF56_05255	ENOG4105CBZ	Short-chain dehydrogenase reductase Sdr
GRF56_05260	ENOG4105C8A	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP (By similarity)
GRF56_05265	ENOG4108MJ3	acetyltransferase
GRF56_05280	ENOG4105EV4	Multidrug resistance protein mdtH
GRF56_05295	ENOG4108Z9I	-acetyltransferase
GRF56_05300	ENOG4105D9U	N-acetyltransferase
GRF56_05310	ENOG4105D9R	oxidoreductase
GRF56_05320	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
GRF56_05325	ENOG4105CSA	Coproporphyrinogen iii oxidase
GRF56_05330	ENOG4105VCN	Rescues the ribosomes stalled at the 3' end of non-stop mRNAs. May induce hydrolysis of the ribosome-bound peptidyl-tRNA. This activity is crucial when the stalled ribosome can not be rescued by the SsrA(tmRNA)-SmpB quality control system
GRF56_05340	ENOG4105DC1	bifunctional purine biosynthesis protein purh
GRF56_05345	ENOG4105C12	Phosphoribosylglycinamide synthetase
GRF56_05365	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
GRF56_05370	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
GRF56_05375	ENOG4105KTH	gatB Yqey
GRF56_05380	ENOG4105VCC	30S ribosomal protein S21
GRF56_05385	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
GRF56_05395	ENOG4105DS2	Anaerobic c4-dicarboxylate transporter
GRF56_05400	ENOG4108IJ0	Aspartate ammonia-lyase
GRF56_05405	ENOG4108YH1	overproduction of this protein in Escherichia coli inhibits the F plasmid-mediated exclusion of bacteriophage T7
GRF56_05415	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
GRF56_05420	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
GRF56_05430	ENOG4105BZU	Histidine kinase
GRF56_05470	ENOG4108IAB	Phoh family
GRF56_05475	ENOG4107T0D	ABC, transporter
GRF56_05480	ENOG4106SMU	thiamine transporter membrane protein
GRF56_05485	ENOG4105DP9	ABC transporter
GRF56_05500	ENOG4105MQS	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
GRF56_05505	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
GRF56_05510	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
GRF56_05515	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
GRF56_05525	ENOG4105YVM	Phosphoesterase, PA-phosphatase related
GRF56_05540	ENOG4105C7K	acetolactate synthase
GRF56_05550	ENOG4108ZP8	Acetolactate synthase small subunit
GRF56_05555	ENOG4108NIW	Leucine export protein LeuE
GRF56_05560	ENOG4107R11	Transcriptional regulator
GRF56_05585	ENOG4105VY0	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters (By similarity)
GRF56_05590	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
GRF56_05600	ENOG4107V40	secretion protein, HlyD family
GRF56_05630	ENOG4105I93	response regulator
GRF56_05635	ENOG4105DUX	Transporter
GRF56_05640	ENOG4105C3Y	UTP-glucose-1-phosphate uridylyltransferase
GRF56_05645	ENOG41083P1	competence protein ComEA helix-hairpin-helix repeat protein
GRF56_05650	ENOG4105C6K	Malic enzyme
GRF56_05655	ENOG4105C6H	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity)
GRF56_05660	ENOG4105PQ6	UPF0208 membrane protein
GRF56_05665	ENOG4105XWI	UPF0304 protein
GRF56_05670	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
GRF56_05675	ENOG4105RH4	Glycine cleavage system transcriptional repressor
GRF56_05680	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
GRF56_05685	ENOG4107EG0	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
GRF56_05690	ENOG4107QWK	SAICAR synthetase
GRF56_05700	ENOG4105EXG	Transcriptional regulator
GRF56_05705	ENOG4108Q67	UPF0319 protein
GRF56_05725	ENOG4105BZU	Histidine kinase
GRF56_05730	ENOG4105C4Q	deoxyguanosinetriphosphate triphosphohydrolase-like protein
GRF56_05740	ENOG4105BZU	Histidine kinase
GRF56_05745	ENOG4105BZU	Histidine kinase
GRF56_05750	ENOG4108N3W	hemolysin secretion protein
GRF56_05755	ENOG4105MDZ	Transcriptional activator rfaH
GRF56_05760	ENOG4105D01	(LipO)protein
GRF56_05765	ENOG4108UMI	ABC transporter, permease
GRF56_05785	ENOG4105EH2	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity)
GRF56_05790	ENOG4105DR1	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)
GRF56_05795	ENOG4105K8N	protein family UPF0079, ATPase
GRF56_05800	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
GRF56_05810	ENOG4105DC6	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity)
GRF56_05815	ENOG4105DKX	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity)
GRF56_05820	ENOG4105KW8	RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity)
GRF56_05825	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
GRF56_05830	ENOG4107QJR	hflk protein
GRF56_05835	ENOG4105EPW	hflc protein
GRF56_05845	ENOG4105EAH	synthase
GRF56_05850	ENOG4105KK9	This protein binds to 23S rRNA in the presence of protein L20 (By similarity)
GRF56_05855	ENOG4105K46	50S ribosomal protein l27
GRF56_05860	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
GRF56_05865	ENOG4105DWD	nucleoside recognition domain protein
GRF56_05875	ENOG4105DEN	Luciferase family
GRF56_05890	ENOG4105DDT	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP (By similarity)
GRF56_05895	ENOG4105NWN	ApaG protein
GRF56_05900	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
GRF56_05905	ENOG4105CEZ	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) (By similarity)
GRF56_05910	ENOG4105DBD	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity)
GRF56_05915	ENOG4105E7H	involved in the assembly of LPS in the outer leaflet of the outer membrane. Determines N-hexane tolerance and is involved in outer membrane permeability. Essential for envelope biogenesis (By similarity)
GRF56_05920	ENOG4105EHM	Aminoglycoside phosphotransferase
GRF56_05925	ENOG4108S0S	Nucleotidyl transferase
GRF56_05930	ENOG41066UG	Regulatory DnaK co-chaperone. Direct interaction between DnaK and DjlA is needed for the induction of the wcaABCDE operon, involved in the synthesis of a colanic acid polysaccharide capsule, possibly through activation of the RcsB RcsC phosphotransfer signaling pathway. The colanic acid capsule may help the bacterium survive conditions outside the host (By similarity)
GRF56_05935	ENOG4105CIN	aminoacyl-histidine dipeptidase
GRF56_05945	ENOG4105DYA	Acts on guanine, xanthine and to a lesser extent hypoxanthine (By similarity)
GRF56_05950	ENOG4105V1F	Fermentation respiration switch protein
GRF56_05965	ENOG4105C2S	Catalyzes the NADPH dependent reduction of L-gamma- glutamyl 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate (By similarity)
GRF56_05980	ENOG4105VYA	Uncharacterized conserved protein (DUF2132)
GRF56_05985	ENOG4105DJ4	phosphatidylserine decarboxylase
GRF56_05995	ENOG4108RBP	3'-to-5' exoribonuclease specific for small oligoribonucleotides (By similarity)
GRF56_06035	ENOG4105VEQ	Cold shock protein
GRF56_06045	ENOG4105C8Q	Methyl-accepting chemotaxis
GRF56_06050	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
GRF56_06055	ENOG4105C7N	Xanthine uracil vitamin C permease
GRF56_06065	ENOG4105C5H	ABC transporter
GRF56_06080	ENOG4105E4C	Lytic transglycosylase catalytic
GRF56_06090	ENOG4105G4C	Periplasmic ligand-binding sensor protein
GRF56_06100	ENOG4105C6Y	Udp-glucose 6-dehydrogenase
GRF56_06110	ENOG4108JQ7	(ABC) transporter
GRF56_06125	ENOG4108IYQ	Binding-protein-dependent transport systems inner membrane component
GRF56_06130	ENOG4108I5X	binding-protein-dependent transport systems inner membrane Component
GRF56_06135	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
GRF56_06155	ENOG4109015	Biopolymer transport protein exbD tolR
GRF56_06170	ENOG4107N1Q	ErfK YbiS YcfS YnhG family protein
GRF56_06175	ENOG4105D07	Signal peptide peptidase, SppA
GRF56_06180	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
GRF56_06185	ENOG41069NU	Nitroreductase
GRF56_06200	ENOG4108JQ1	Dehydrogenase
GRF56_06205	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
GRF56_06210	ENOG4105CIS	alcohol dehydrogenase
GRF56_06215	ENOG4105HEI	LysR family (Transcriptional regulator
GRF56_06220	ENOG4105CI1	PTS System
GRF56_06225	ENOG4108IA2	Sodium pantothenate symporter
GRF56_06235	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
GRF56_06240	ENOG4105KM4	Acetyl-CoA carboxylase, biotin carboxyl carrier protein
GRF56_06245	ENOG4108Z38	Catalyzes a trans-dehydration via an enolate intermediate (By similarity)
GRF56_06250	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
GRF56_06260	ENOG4105BZU	Histidine kinase
GRF56_06270	ENOG4109039	Involved in the biogenesis of TorA. Acts on TorA before the insertion of the molybdenum cofactor and, as a result, probably favors a conformation of the apoenzyme that is competent for acquiring the cofactor (By similarity)
GRF56_06275	ENOG4108EM1	reductase
GRF56_06280	ENOG4105CUW	cytochrome C-TYPE protein
GRF56_06285	ENOG4106WF9	DNA-binding transcriptional regulator TorR
GRF56_06295	ENOG4108SV3	Tmao reductase system periplasmic protein tort
GRF56_06310	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
GRF56_06315	ENOG4108Z11	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes (By similarity)
GRF56_06320	ENOG4105D1W	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity)
GRF56_06335	ENOG4108UTT	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity)
GRF56_06340	ENOG4107YIM	Involved in the transcription termination process (By similarity)
GRF56_06345	ENOG4105CG2	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity)
GRF56_06350	ENOG4108ZAI	phosphatidylglycerophosphatase a
GRF56_06355	ENOG4108JQ6	ABC transporter
GRF56_06365	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
GRF56_06375	ENOG41069P5	Protein slyX homolog
GRF56_06385	ENOG4108V1T	peptidylprolyl cis-trans isomerase
GRF56_06390	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
GRF56_06410	ENOG4105CGH	5'-nucleotidase
GRF56_06415	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
GRF56_06420	ENOG4105CTB	Polyprenyl synthetase
GRF56_06425	ENOG41067QG	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
GRF56_06430	ENOG4105E14	MotA TolQ exbB proton channel
GRF56_06435	ENOG4107XSU	flagellar motor protein motb
GRF56_06440	ENOG4108UKH	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
GRF56_06450	ENOG4105HBR	Rna-binding protein
GRF56_06455	ENOG4105F7M	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit (By similarity)
GRF56_06460	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
GRF56_06465	ENOG4105EEI	dihydropteroate synthase
GRF56_06470	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
GRF56_06475	ENOG4105CP7	Triose-phosphate isomerase
GRF56_06495	ENOG4105K7D	Required for maturation of 30S ribosomal subunits (By similarity)
GRF56_06500	ENOG4105CHV	Transcription elongation factor NusA
GRF56_06505	ENOG4107QHU	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
GRF56_06510	ENOG4105KG7	Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity)
GRF56_06515	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
GRF56_06520	ENOG4105K77	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity)
GRF56_06525	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
GRF56_06530	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
GRF56_06535	ENOG4108Z4W	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis (By similarity)
GRF56_06540	ENOG4105BZU	Histidine kinase
GRF56_06545	ENOG4105C8Q	Methyl-accepting chemotaxis
GRF56_06550	ENOG4108V3W	Chemotaxis protein, CheW
GRF56_06560	ENOG4105CBS	Chea signal transduction histidine kinase
GRF56_06570	ENOG4108VYJ	response regulator receiver protein
GRF56_06575	ENOG4105C8Q	Methyl-accepting chemotaxis
GRF56_06580	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
GRF56_06590	ENOG4105N14	lysine exporter protein LysE YggA
GRF56_06595	ENOG4105CFP	Peptidase U32
GRF56_06600	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
GRF56_06640	ENOG4105CTD	carboxy-peptidase
GRF56_06665	ENOG4105E1F	short-chain dehydrogenase reductase
GRF56_06675	ENOG4105C8Q	Methyl-accepting chemotaxis
GRF56_06710	ENOG4105CRD	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P) (By similarity)
GRF56_06715	ENOG4105F0Z	galactose-1-phosphate uridylyltransferase
GRF56_06720	ENOG4105CMR	udp-glucose 4-epimerase
GRF56_06725	ENOG41060NJ	transcriptional regulator
GRF56_06730	ENOG4108KDD	Involved in the transport of maltose and maltodextrins (By similarity)
GRF56_06745	ENOG4105C8Q	Methyl-accepting chemotaxis
GRF56_06755	ENOG4107FKK	extracellular solute-binding protein family 1
GRF56_06765	ENOG4105EG2	ABC transporter, permease
GRF56_06775	ENOG4105C4C	beta-galactosidase
GRF56_06780	ENOG4105CI1	PTS System
GRF56_06790	ENOG4105CA9	Pyruvate kinase
GRF56_06805	ENOG4105W5Q	DNA repair protein (RadC
GRF56_06850	ENOG4108NF7	phage-type endonuclease
GRF56_06880	ENOG4105CQC	Prephenate dehydratase
GRF56_06895	ENOG4105FD2	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) (By similarity)
GRF56_06910	ENOG4107SEY	Conserved Protein
GRF56_06915	ENOG4108XDN	Transcriptional regulator
GRF56_06920	ENOG4105CVP	deoxyribo-dipyrimidine photolyase
GRF56_06930	ENOG4107FW0	short-chain dehydrogenase reductase
GRF56_06945	ENOG4105CV9	cyclopropane-fatty-acyl-phospholipid synthase
GRF56_06975	ENOG4105CJ2	(LipO)protein
GRF56_06980	ENOG4105D26	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. The first step is catalyzed by NqrF, which accepts electrons from NADH and reduces ubiquinone-1 to ubisemiquinone by a one-electron transfer pathway (By similarity)
GRF56_06985	ENOG4108IUB	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
GRF56_06990	ENOG4105F5D	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
GRF56_06995	ENOG4106I92	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
GRF56_07000	ENOG4108J5C	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
GRF56_07005	ENOG4105DWQ	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
GRF56_07010	ENOG4105M85	Bola protein
GRF56_07015	ENOG4105D8J	Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle (By similarity)
GRF56_07025	ENOG4108R5K	PPIases accelerate the folding of proteins (By similarity)
GRF56_07030	ENOG4105EYM	Major Facilitator superfamily
GRF56_07035	ENOG4105DRB	nucleoside-specific channel-forming protein
GRF56_07040	ENOG4108VPT	UPF0234 protein
GRF56_07045	ENOG4108JZF	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity)
GRF56_07050	ENOG4107S0N	DJ-1 family
GRF56_07060	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
GRF56_07065	ENOG4105C8Q	Methyl-accepting chemotaxis
GRF56_07070	ENOG4105ETT	transcriptional Regulator, LysR family
GRF56_07080	ENOG4105M08	Membrane
GRF56_07085	ENOG4105EZ6	Catalyzes the 2'-O-methylation at nucleotide C2498 in 23S rRNA (By similarity)
GRF56_07095	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
GRF56_07100	ENOG4105CIQ	May have a role in processing of nucleic acids. It is probably not an exonuclease
GRF56_07105	ENOG4105EWT	decarboxylase family
GRF56_07110	ENOG4105BZU	Histidine kinase
GRF56_07120	ENOG4107R1K	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) (By similarity)
GRF56_07125	ENOG4108T6E	Interacts with the SecY protein in vivo. May bind preferentially to an uncomplexed state of SecY, thus functioning either as a chelating agent for excess SecY in the cell or as a regulatory factor that negatively controls the translocase function (By similarity)
GRF56_07130	ENOG4105EXF	Zn-ribbon-containing, possibly nucleic-acid-binding protein
GRF56_07155	ENOG4105WP7	tRNA pseudouridine synthase C
GRF56_07160	ENOG4105DR9	pseudouridine synthase
GRF56_07165	ENOG4105QDK	Flavodoxin
GRF56_07175	ENOG4107W52	maltose operon periplasmic protein
GRF56_07180	ENOG4105CI1	PTS System
GRF56_07185	ENOG4108T8E	UPF0325 protein
GRF56_07190	ENOG4105DMJ	Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate (By similarity)
GRF56_07195	ENOG4105E1P	Modifies, by uridylylation or deuridylylation the PII (GlnB) regulatory protein (By similarity)
GRF56_07200	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
GRF56_07205	ENOG4105CE9	30S ribosomal protein S2
GRF56_07210	ENOG4105CU7	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity)
GRF56_07215	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
GRF56_07220	ENOG4108VCV	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity)
GRF56_07225	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
GRF56_07230	ENOG4105KNE	Phosphatidate cytidylyltransferase
GRF56_07235	ENOG4105CEA	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity)
GRF56_07240	ENOG4105DZP	Membrane-associated zinc metalloprotease
GRF56_07245	ENOG4105E1Z	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
GRF56_07250	ENOG4108RFI	Molecular chaperone that interacts specifically with outer membrane proteins, thus maintaining the solubility of early folding intermediates during passage through the periplasm (By similarity)
GRF56_07255	ENOG4105D7M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
GRF56_07260	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
GRF56_07265	ENOG4105DAF	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
GRF56_07270	ENOG4105D0V	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
GRF56_07275	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
GRF56_07280	ENOG4105C0B	DNA polymerase III (alpha subunit)
GRF56_07285	ENOG4107QM9	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA (By similarity)
GRF56_07295	ENOG4105CW3	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
GRF56_07300	ENOG4105BZG	amino acid carrier protein
GRF56_07305	ENOG4105F8C	transglutaminase domain-containing protein
GRF56_07315	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
GRF56_07325	ENOG4105G2Y	Transcriptional regulator
GRF56_07330	ENOG4105DUX	Transporter
GRF56_07335	ENOG4107Y66	Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity)
GRF56_07345	ENOG4105D7Z	glutathione synthase
GRF56_07350	ENOG4105QF0	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity)
GRF56_07360	ENOG4105GPY	SprT protein
GRF56_07365	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
GRF56_07370	ENOG4105CV1	Transketolase (EC 2.2.1.1)
GRF56_07390	ENOG4106KR7	LysR family Transcriptional regulator
GRF56_07395	ENOG4105TMR	Functions as a holding molecular chaperone (holdase) which stabilizes unfolding intermediates and rapidly releases them in an active form once stress has abated. Plays an important role in protecting cells from severe heat shock and starvation, as well as in acid resistance of stationary-phase cells. It catalyzes the conversion of methylglyoxal (MG) to D-lactate in a single glutathione (GSH)-independent step (By similarity)
GRF56_07405	ENOG4105KME	endoribonuclease L-psp
GRF56_07415	ENOG4105ED7	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling (By similarity)
GRF56_07420	ENOG4105DR5	peptidase
GRF56_07425	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
GRF56_07440	ENOG4105C7K	acetolactate synthase
GRF56_07450	ENOG4105EQ2	LysR family Transcriptional regulator
GRF56_07455	ENOG4105C44	Serine transporter
GRF56_07470	ENOG4105EXG	Transcriptional regulator
GRF56_07475	ENOG4105DVH	amino acid
GRF56_07480	ENOG4108M3R	transcriptional activator CadC
GRF56_07485	ENOG4105D5Q	Arginine ornithine antiporter
GRF56_07490	ENOG4105CXN	decarboxylase
GRF56_07495	ENOG4107XGF	functions in a salvage pathway. Uses pyridoxamine (By similarity)
GRF56_07510	ENOG4105C9K	Endothelin-converting enzyme 1
GRF56_07515	ENOG4105D3U	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
GRF56_07520	ENOG4105BZU	Histidine kinase
GRF56_07555	ENOG4107T9C	Alpha amylase catalytic region
GRF56_07585	ENOG4105DIT	ErfK YbiS YcfS YnhG family protein
GRF56_07590	ENOG4105EAQ	(twin-arginine translocation) pathway signal
GRF56_07600	ENOG4105EN6	Membrane
GRF56_07605	ENOG4105EXN	Sulfate transport protein CysZ
GRF56_07610	ENOG4105CDB	Required for chromosome condensation and partitioning (By similarity)
GRF56_07615	ENOG4107NPY	receptor for the septal ring structure, may anchor it to the inner-membrane (By similarity)
GRF56_07620	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
GRF56_07630	ENOG4105CJD	(Anaerobic) ribonucleoside-triphosphate reductase
GRF56_07635	ENOG4108RDD	Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine (By similarity)
GRF56_07665	ENOG4105J12	Multidrug resistance protein mdtN
GRF56_07670	ENOG4108US0	Transcription regulator that can specifically activate or repress expression of target genes (By similarity)
GRF56_07680	ENOG4107R1I	NAD-dependent malic enzyme
GRF56_07685	ENOG4105CEQ	signal transduction histidine kinase regulating citrate malate metabolism
GRF56_07690	ENOG4106YYS	transcriptional regulatory protein
GRF56_07695	ENOG4108IPJ	Membrane
GRF56_07705	ENOG4105C26	Dehydrogenase
GRF56_07710	ENOG4108JU9	GAF modulated sigma54 specific transcriptional regulator Fis family
GRF56_07715	ENOG4108ZI4	Glyoxalase Bleomycin resistance protein (Dioxygenase
GRF56_07720	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
GRF56_07725	ENOG4105BZU	Histidine kinase
GRF56_07735	ENOG4105ERG	peptidase m48, ste24p
GRF56_07750	ENOG4106N3A	copper homeostasis protein cutc
GRF56_07755	ENOG4108V1T	peptidylprolyl cis-trans isomerase
GRF56_07770	ENOG4105PTV	Nudix Hydrolase
GRF56_07795	ENOG4105BZG	amino acid carrier protein
GRF56_07805	ENOG4108KMH	lipoate-protein ligase a
GRF56_07810	ENOG4105C2W	permease
GRF56_07815	ENOG4105FSR	swimming returnes to normal when residues 206-207 are both mutated to Ala. Overexpression also leads to a reduction in flagellar abundance and a 20-fold increase in c-di- GMP levels in vivo. Required for aminoglycoside-mediated induction of biofilm formation, it also plays a lesser role in biofilm production in response to other classes of translation inhibitors. The c-di-GMP produced by this enzyme up-regulates poly-GlcNAc production as well as the biofilm synthesis protein PgaD, although c-di-GMP is probably not the main inducing principle. Cyclic-di- GMP is a second messenger which controls cell surface-associated traits in bacteria
GRF56_07820	ENOG4105RKX	Protein of unknown function (DUF2498)
GRF56_07825	ENOG4105UQX	Mate efflux family protein
GRF56_07830	ENOG4105ECQ	AraC Family Transcriptional Regulator
GRF56_07835	ENOG4107R1I	NAD-dependent malic enzyme
GRF56_07840	ENOG4105UYK	outer membrane protein a
GRF56_07850	ENOG4105UYK	outer membrane protein a
GRF56_07865	ENOG4107R7I	amino acid
GRF56_07870	ENOG4105D78	K07001 NTE family protein
GRF56_07875	ENOG4105BZU	Histidine kinase
GRF56_07880	ENOG4105J12	Multidrug resistance protein mdtN
GRF56_07890	ENOG4105CCT	upf0313 protein
GRF56_07895	ENOG4107RRE	RNA-directed DNA polymerase
GRF56_07945	ENOG4105EP9	oxidoreductase
GRF56_07950	ENOG4108Z0T	Part of a sulfur-relay system (By similarity)
GRF56_07955	ENOG4105EM2	membrane
GRF56_07960	ENOG4108MN8	Membrane
GRF56_07975	ENOG41064BZ	L-xylulose 5-phosphate 3-epimerase
GRF56_07980	ENOG4108K4B	hydrolase
GRF56_08015	ENOG4105F8D	glycoside hydrolase family 4
GRF56_08020	ENOG4105EZV	Transcriptional regulator
GRF56_08025	ENOG4105VCP	PTS System
GRF56_08030	ENOG4105CS2	ec 3.2.1.21
GRF56_08035	ENOG4105CK1	PTS System
GRF56_08040	ENOG4105VZJ	PTS System
GRF56_08080	ENOG4108VAU	general secretion pathway protein G
GRF56_08085	ENOG4105D7Q	type ii secretion system
GRF56_08090	ENOG4107QHF	type ii secretion system protein e
GRF56_08095	ENOG4105GVR	general secretion pathway protein D
GRF56_08115	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
GRF56_08135	ENOG4105C6T	cysteine synthase
GRF56_08140	ENOG4105KZ7	phosphocarrier protein hpr
GRF56_08150	ENOG4105C5Y	PTS System
GRF56_08155	ENOG4105BZU	Histidine kinase
GRF56_08160	ENOG4105C9K	Endothelin-converting enzyme 1
GRF56_08175	ENOG4105EGS	Mechanosensitive ion channel
GRF56_08180	ENOG4105CA9	Pyruvate kinase
GRF56_08190	ENOG4105C8E	extradiol ring-cleavage dioxygenase class IIi protein subunit b
GRF56_08210	ENOG4105EYH	Exonuclease
GRF56_08215	ENOG4107RH8	nuclease SbcCD subunit D
GRF56_08225	ENOG4105DH7	May be involved in recombination (By similarity)
GRF56_08230	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
GRF56_08235	ENOG4108V1T	peptidylprolyl cis-trans isomerase
GRF56_08250	ENOG4105CUB	amino acid
GRF56_08260	ENOG4105CUB	amino acid
GRF56_08265	ENOG4108JPW	Aminotransferase
GRF56_08270	ENOG4105C26	Dehydrogenase
GRF56_08275	ENOG4107VRI	Transcriptional regulator
GRF56_08280	ENOG4105CJP	fad dependent oxidoreductase
GRF56_08310	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
GRF56_08320	ENOG4105CPW	cytochrome b561
GRF56_08325	ENOG4108R96	Methyltransferase, YaeB family
GRF56_08345	ENOG4108JJ8	(ABC) transporter
GRF56_08350	ENOG4108JJ9	ABC, transporter
GRF56_08370	ENOG41065U4	response regulator
GRF56_08380	ENOG4108YYX	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. Modulates RNA-binding and helicase activities of the degradosome (By similarity)
GRF56_08410	ENOG4105D6J	arsenicaL-resistance protein
GRF56_08415	ENOG4105K89	arsenate reductase
GRF56_08420	ENOG4105D9N	nucleoside
GRF56_08440	ENOG4105S2T	inner membrane protein YbcI
GRF56_08455	ENOG4105F6H	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate (By similarity)
GRF56_08460	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
GRF56_08465	ENOG4105DK0	Indole-3-glycerol phosphate synthase
GRF56_08470	ENOG4108I0Q	anthranilate phosphoribosyltransferase
GRF56_08475	ENOG4108EFP	Anthranilate synthase component II
GRF56_08480	ENOG4105CRQ	synthase (Component I)
GRF56_08485	ENOG4105DB7	PHP domain protein
GRF56_08490	ENOG4107RTD	sua5 ycio yrdc ywlc family protein
GRF56_08500	ENOG4105K8I	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves (By similarity)
GRF56_08505	ENOG4105FE9	pseudouridine synthase
GRF56_08510	ENOG4105C29	acyl-CoA thioesterase
GRF56_08515	ENOG4105VS7	Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue. This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon. When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation (By similarity)
GRF56_08520	ENOG4106FVC	RNA methyltransferase
GRF56_08535	ENOG4105D5I	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate (By similarity)
GRF56_08540	ENOG4105D98	threonine synthase
GRF56_08545	ENOG4105CDB	Required for chromosome condensation and partitioning (By similarity)
GRF56_08560	ENOG4105CBM	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 (By similarity)
GRF56_08605	ENOG4105WH1	Two component transcriptional regulator luxr family
GRF56_08610	ENOG4105BZU	Histidine kinase
GRF56_08620	ENOG4105C8Q	Methyl-accepting chemotaxis
GRF56_08630	ENOG4105DUM	transcriptional regulator, lysR family
GRF56_08635	ENOG4105HMI	Membrane
GRF56_08645	ENOG4105WH1	Two component transcriptional regulator luxr family
GRF56_08650	ENOG4108JUA	Transcriptional regulator
GRF56_08655	ENOG4105CNW	domain protein
GRF56_08660	ENOG4108EQM	faD-dependent pyridine nucleotide-disulfide oxidoreductase
GRF56_08675	ENOG4105WH1	Two component transcriptional regulator luxr family
GRF56_08685	ENOG4105DQQ	Major facilitator superfamily MFS_1
GRF56_08690	ENOG4105CRU	nitrate reductase, alpha subunit
GRF56_08695	ENOG4108IUE	nitrate reductase beta subunit
GRF56_08700	ENOG4105R3A	Nitrate reductase
GRF56_08705	ENOG41076YT	nitrate reductase, gamma subunit
GRF56_08730	ENOG4105BZU	Histidine kinase
GRF56_08735	ENOG4105BZU	Histidine kinase
GRF56_08770	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
GRF56_08785	ENOG4105VYW	UPF0251 protein
GRF56_08800	ENOG4108IG5	Transcriptional regulator
GRF56_08805	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
GRF56_08810	ENOG4105BZS	acriflavin resistance protein
GRF56_08815	ENOG4105C1B	dTDP-glucose 4-6-dehydratase
GRF56_08820	ENOG4105DBZ	Dtdp-4-dehydrorhamnose reductase
GRF56_08830	ENOG4108URP	Dtdp-4-dehydrorhamnose 3,5-epimerase
GRF56_08835	ENOG4107QK7	reductase
GRF56_08840	ENOG4105EJZ	Glucose-1-phosphate cytidylyltransferase
GRF56_08845	ENOG4105FAW	cDP-glucose 4,6-dehydratase
GRF56_08850	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
GRF56_08855	ENOG4108SMP	Nad-dependent epimerase dehydratase
GRF56_08865	ENOG4107S6X	Glycosyl transferase, family 2
GRF56_08875	ENOG4105BZ1	(ABC) transporter
GRF56_08895	ENOG4105E2K	Glycosyl transferase (Group 1
GRF56_08900	ENOG4108TJN	glycosyl transferase group 1
GRF56_08905	ENOG4105CJT	Mannose-1-phosphate guanylyltransferase
GRF56_08910	ENOG4106ECQ	phosphomannomutase
GRF56_08915	ENOG4105D3Q	Sugar transferase
GRF56_08940	ENOG4108W78	Pfam:DUF1017
GRF56_08945	ENOG4105E3R	(LipO)protein
GRF56_08950	ENOG4108QY5	Ferric enterobactin transport protein
GRF56_08960	ENOG4108YX2	DNA-binding protein
GRF56_08965	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
GRF56_08970	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
GRF56_08975	ENOG4105DJY	efflux transporter, rnd family, mfp subunit
GRF56_08980	ENOG4105E2M	Manganese-dependent inorganic pyrophosphatase
GRF56_08985	ENOG4105C4F	May be involved in recombinational repair of damaged DNA (By similarity)
GRF56_08990	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
GRF56_08995	ENOG4105K90	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
GRF56_09000	ENOG4105CFG	Acts as a chaperone (By similarity)
GRF56_09005	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
GRF56_09015	ENOG4105D7K	pfkb domain protein
GRF56_09025	ENOG4108HKT	sucrose-6-phosphate hydrolase
GRF56_09030	ENOG4105WBN	Transcriptional regulator (LacI family
GRF56_09045	ENOG4107SA8	fad-dependent pyridine nucleotide-disulfide oxidoreductase
GRF56_09065	ENOG4105KFG	YeeE YedE family protein
GRF56_09085	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
GRF56_09090	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
GRF56_09095	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
GRF56_09100	ENOG4105BZU	Histidine kinase
GRF56_09105	ENOG4107RMF	Catalyzes both the ATP-dependent activation of exogenously supplied lipoate to lipoyl-AMP and the transfer of the activated lipoyl onto the lipoyl domains of lipoate-dependent enzymes (By similarity)
GRF56_09115	ENOG4105K4T	epimerase
GRF56_09120	ENOG4105YRI	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
GRF56_09125	ENOG4105C0A	alcohol dehydrogenase
GRF56_09130	ENOG4107SXA	Phosphorylase
GRF56_09135	ENOG4105D3G	Pseudouridine synthase
GRF56_09140	ENOG4105DU0	nucleoside hydrolase
GRF56_09155	ENOG4105RX8	Protein of unknown function (DUF1523)
GRF56_09165	ENOG410829K	Lysine exporter protein (Lyse ygga)
GRF56_09180	ENOG4105C3N	Participates in control of cell volume in low-osmolarity conditions (By similarity)
GRF56_09195	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
GRF56_09200	ENOG4105KUZ	arsenate reductase
GRF56_09210	ENOG4105CEE	C4-dicarboxylate transporter
GRF56_09215	ENOG4105CH2	amidohydrolase
GRF56_09225	ENOG4105DS2	Anaerobic c4-dicarboxylate transporter
GRF56_09235	ENOG4105C5S	asparaginyl-tRNA synthetase
GRF56_09250	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
GRF56_09255	ENOG4105CZF	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism (By similarity)
GRF56_09260	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
GRF56_09265	ENOG410626R	Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity)
GRF56_09270	ENOG4105E78	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity)
GRF56_09275	ENOG4105D0M	Protease HtpX homolog
GRF56_09280	ENOG4107SDU	Methyl-accepting chemotaxis
GRF56_09285	ENOG4105QVC	MOSC domain-containing protein
GRF56_09285	ENOG4105QVC	MOSC domain-containing protein
GRF56_09300	ENOG4105D95	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin (By similarity)
GRF56_09310	ENOG4108535	NAD dependent epimerase/dehydratase family
GRF56_09315	ENOG4105NAU	thioesterase Superfamily protein
GRF56_09330	ENOG41090BQ	Glutaredoxin
GRF56_09335	ENOG4106HRJ	d-alanyl-d-alanine carboxypeptidase
GRF56_09340	ENOG4105CFI	type iii restriction protein res subunit
GRF56_09345	ENOG4105EFX	secretion protein, HlyD family
GRF56_09350	ENOG4105KK7	inner membrane protein YiaW
GRF56_09360	ENOG4108NEV	two component transcriptional regulator, LytTR family
GRF56_09365	ENOG4108HRK	Histidine kinase
GRF56_09370	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
GRF56_09375	ENOG4105DIJ	Phosphoethanolamine transferase
GRF56_09380	ENOG4105E2R	ROK family
GRF56_09385	ENOG4105CE4	GlcNAc 6-P deacetylase
GRF56_09390	ENOG4105CKA	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion (By similarity)
GRF56_09395	ENOG4105CI1	PTS System
GRF56_09400	ENOG4105E2D	ec 3.2.1.52
GRF56_09405	ENOG4105CX6	glutaminyL-tRNA synthetase
GRF56_09410	ENOG41090R7	Ferric uptake
GRF56_09420	ENOG4105MHQ	Low-potential electron donor to a number of redox enzymes (By similarity)
GRF56_09425	ENOG4105NNH	LexA regulated protein
GRF56_09435	ENOG4105EV9	Alpha Beta Hydrolase
GRF56_09440	ENOG4107CDU	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated (By similarity)
GRF56_09445	ENOG4107QIX	Phosphoglucomutase (EC 5.4.2.2
GRF56_09460	ENOG4105CVE	Lytic murein transglycosylase
GRF56_09465	ENOG4108T9J	Cdp-alcohol phosphatidyltransferase
GRF56_09470	ENOG4108VGW	abc transporter atp-binding protein
GRF56_09480	ENOG4105VNH	ABC transporter solute-binding protein
GRF56_09490	ENOG4107ZN8	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity (By similarity)
GRF56_09500	ENOG4105KQ5	peptidylprolyl cis-trans isomerase
GRF56_09510	ENOG4105CFU	surface antigen
GRF56_09515	ENOG4105MA0	exported protein
GRF56_09535	ENOG4108WPH	sigma 54 modulation protein ribosomal protein S30EA
GRF56_09540	ENOG4105BZU	Histidine kinase
GRF56_09545	ENOG4107SC1	transglycosylase
GRF56_09550	ENOG41060NJ	transcriptional regulator
GRF56_09555	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
GRF56_09560	ENOG4105D05	Receptor
GRF56_09565	ENOG4105E4F	Isochorismate synthase
GRF56_09570	ENOG4108IQC	2,3-dihydroxybenzoate-AMP ligase
GRF56_09575	ENOG4105WQI	isochorismatase
GRF56_09580	ENOG4105X17	23-dihydro-2,3-dihydroxybenzoate dehydrogenase
GRF56_09585	ENOG4105C0W	non-ribosomal peptide synthetase
GRF56_09595	ENOG4107RUY	(E1 component), alpha subunit
GRF56_09600	ENOG4105CPP	Dehydrogenase, E1 component
GRF56_09605	ENOG4107QSN	dihydrolipoamide acetyltransferase
GRF56_09610	ENOG4105VEQ	Cold shock protein
GRF56_09635	ENOG4105E43	Extracellular solute-binding protein, family 5
GRF56_09640	ENOG4105N2W	Transcriptional regulator
GRF56_09645	ENOG4105C6N	Formate acetyltransferase
GRF56_09650	ENOG4105F1A	Pyruvate formate-lyase
GRF56_09655	ENOG4107T9Z	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
GRF56_09665	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
GRF56_09670	ENOG4105I08	Pseudouridine synthase
GRF56_09680	ENOG4107QSI	ABC, transporter
GRF56_09685	ENOG4108RE9	Phosphodiesterase
GRF56_09700	ENOG4107ESN	Flagella basal body P-ring formation protein flgA
GRF56_09705	ENOG4107R88	Chemotaxis protein (CheV)
GRF56_09710	ENOG4105BZU	Histidine kinase
GRF56_09715	ENOG4105K88	Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body (By similarity)
GRF56_09720	ENOG4108ZC9	flagellar basal-body rod protein flgc
GRF56_09725	ENOG4105W00	Flagellar hook capping protein
GRF56_09730	ENOG4105BZE	flagellar hook protein, FlgE
GRF56_09735	ENOG4108KPB	Flagellar basal-body rod protein FlgF
GRF56_09740	ENOG4105CGA	flagellar basal-body rod protein FlgG
GRF56_09745	ENOG4107W7W	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity)
GRF56_09750	ENOG4105D92	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity)
GRF56_09755	ENOG4108ZW7	flagellar rod assembly protein muramidase flgj
GRF56_09765	ENOG4105DTJ	flagellar hook-associated protein
GRF56_09770	ENOG4105CJW	magnesium transporter
GRF56_09775	ENOG4105C9X	ppx gppa phosphatase
GRF56_09780	ENOG4105CUU	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) (By similarity)
GRF56_09785	ENOG4105RH4	Glycine cleavage system transcriptional repressor
GRF56_09795	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
GRF56_09800	ENOG4105BZU	Histidine kinase
GRF56_09805	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
GRF56_09810	ENOG4107QNR	UPF0135 protein
GRF56_09815	ENOG4108V3E	phosphoribosylglycinamide formyltransferase
GRF56_09820	ENOG4105CXB	phosphoribosylaminoimidazole synthetase
GRF56_09825	ENOG4105CZ5	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate (By similarity)
GRF56_09840	ENOG4108I9X	Isocitrate lyase
GRF56_09845	ENOG4107QP3	malate synthase g
GRF56_09855	ENOG4108Z6B	deaminase
GRF56_09860	ENOG4105C8U	phosphate abc transporter
GRF56_09865	ENOG4105E2Z	phosphate ABC transporter (Permease
GRF56_09870	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
GRF56_09880	ENOG4105C37	(CBS) domain
GRF56_09890	ENOG4105C3R	Methionine synthase
GRF56_09895	ENOG4105D5Q	Arginine ornithine antiporter
GRF56_09910	ENOG4105CDA	abc transporter atp-binding protein
GRF56_09915	ENOG4105E5Q	amino acid AbC transporter
GRF56_09920	ENOG4106PMH	Extracellular solute-binding protein family 3
GRF56_09925	ENOG4105BZU	Histidine kinase
GRF56_09930	ENOG4105CXY	transporter
GRF56_09935	ENOG4105BZU	Histidine kinase
GRF56_09940	ENOG4108KX4	response regulator
GRF56_09945	ENOG4105NXH	GreA GreB family elongation factor
GRF56_09965	ENOG4105G6Z	alkaline phosphatase
GRF56_09970	ENOG4105C9W	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity (By similarity)
GRF56_09975	ENOG4105DGU	Histone deacetylase
GRF56_09985	ENOG4105DVT	helicase
GRF56_10000	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
GRF56_10010	ENOG4107RAB	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
GRF56_10015	ENOG4107QN8	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
GRF56_10050	ENOG4105K59	histidine triad (HIT) protein
GRF56_10055	ENOG4108NVR	Methyl-accepting chemotaxis
GRF56_10065	ENOG4105CD3	dihydroorotase
GRF56_10080	ENOG4105CK2	sodium dicarboxylate symporter
GRF56_10085	ENOG4105C8Q	Methyl-accepting chemotaxis
GRF56_10095	ENOG4105CKW	Inner membrane protein yedI
GRF56_10105	ENOG4105C2W	permease
GRF56_10115	ENOG4105CEP	NADH dehydrogenase
GRF56_10125	ENOG4105F1A	Pyruvate formate-lyase
GRF56_10130	ENOG4105BZU	Histidine kinase
GRF56_10135	ENOG4107QMW	pyridine nucleotide-disulfide oxidoreductase
GRF56_10145	ENOG4105DN3	alpha-2-macroglobulin domain protein
GRF56_10150	ENOG4108JQB	penicillin-binding protein 1C
GRF56_10220	ENOG4105D8I	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS (By similarity)
GRF56_10230	ENOG4105EN6	Membrane
GRF56_10240	ENOG4105I03	Flagellin
GRF56_10245	ENOG4105I03	Flagellin
GRF56_10260	ENOG4105MQ3	flagellar protein FliS
GRF56_10295	ENOG4105EQQ	protein containing aminopeptidase domain
GRF56_10310	ENOG4105D2T	synthase
GRF56_10320	ENOG4105F0R	Cytidylyltransferase
GRF56_10335	ENOG4105CHR	reductase
GRF56_10340	ENOG4105CEY	Amp-dependent synthetase and ligase
GRF56_10355	ENOG4105CND	Glycosyl transferase, family 2
GRF56_10360	ENOG4107R6R	udp-galactopyranose mutase
GRF56_10365	ENOG4105C0K	Gdp-mannose 4,6-dehydratase
GRF56_10410	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
GRF56_10415	ENOG4105C5E	polysaccharide biosynthesis protein
GRF56_10425	ENOG4105DH2	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group (By similarity)
GRF56_10430	ENOG4105DUF	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively (By similarity)
GRF56_10445	ENOG4108NVR	Methyl-accepting chemotaxis
GRF56_10460	ENOG4105CYM	Glutathione S-transferase
GRF56_10465	ENOG4105E5M	Multidrug resistance protein D
GRF56_10470	ENOG4105CBN	LysR family transcriptional regulator
GRF56_10475	ENOG4107H9G	Necessary for formate dehydrogenase activity (By similarity)
GRF56_10480	ENOG4107QKC	Oxidoreductase alpha (molybdopterin) subunit
GRF56_10490	ENOG4107YUN	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division (By similarity)
GRF56_10500	ENOG4105D0A	hydroxylase
GRF56_10505	ENOG4105EAK	ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family
GRF56_10510	ENOG4105D43	The glycine cleavage system catalyzes the degradation of glycine (By similarity)
GRF56_10515	ENOG4105KE9	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity)
GRF56_10520	ENOG4105CBI	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
GRF56_10550	ENOG4105DZR	Type I site-specific deoxyribonuclease
GRF56_10610	ENOG4105C0D	helicase
GRF56_10620	ENOG4107RHT	methyl-accepting chemotaxis sensory transducer with Pas Pac sensor
GRF56_10640	ENOG4105C85	amino acid
GRF56_10650	ENOG4105CF9	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation (By similarity)
GRF56_10655	ENOG4108HRN	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate (By similarity)
GRF56_10670	ENOG4105D01	(LipO)protein
GRF56_10675	ENOG4105E68	Sulfatase
GRF56_10680	ENOG4105PAN	UPF0352 protein
GRF56_10685	ENOG4106V8H	Nucleoid-associated protein
GRF56_10690	ENOG4107FKK	extracellular solute-binding protein family 1
GRF56_10695	ENOG4105D56	permease protein
GRF56_10700	ENOG4105EG2	ABC transporter, permease
GRF56_10705	ENOG4108IJ9	(ABC) transporter
GRF56_10710	ENOG4105CSR	polyphosphate kinase 2
GRF56_10730	ENOG41082K8	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Interacts with IscS and stimulates its activity. Then, accepts a sulfur from IscS and transfers it in turn to TusD (By similarity)
GRF56_10735	ENOG4105ERG	peptidase m48, ste24p
GRF56_10745	ENOG4105K89	arsenate reductase
GRF56_10755	ENOG4108ZYK	Acyl carrier protein phosphodiesterase
GRF56_10760	ENOG4106PMH	Extracellular solute-binding protein family 3
GRF56_10765	ENOG4105DYB	Isoaspartyl dipeptidase
GRF56_10770	ENOG4105DWU	Membrane
GRF56_10775	ENOG4108JEH	abc transporter atp-binding protein
GRF56_10780	ENOG4106PMH	Extracellular solute-binding protein family 3
GRF56_10785	ENOG4105DSP	amino acid AbC transporter
GRF56_10790	ENOG4106YG3	ABC transporter
GRF56_10805	ENOG4108W1A	pseudouridine synthase
GRF56_10815	ENOG4105E6K	4-Hydroxyphenylpyruvate dioxygenase
GRF56_10820	ENOG4105F1J	Homogentisate 1,2-dioxygenase
GRF56_10830	ENOG4108RXX	maleylacetoacetate isomerase
GRF56_10840	ENOG4105D42	Cleaves the N-terminal amino acid of tripeptides (By similarity)
GRF56_10845	ENOG4105CEE	C4-dicarboxylate transporter
GRF56_10855	ENOG4105CAQ	asparagine synthetase
GRF56_10865	ENOG4105CKD	glutathione-regulated potassium-efflux system protein
GRF56_10870	ENOG4105D4U	had-superfamily hydrolase, subfamily iia
GRF56_10875	ENOG4105EKD	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism (By similarity)
GRF56_10885	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
GRF56_10890	ENOG4105EE5	Membrane protein terC
GRF56_10900	ENOG4105CQB	FAD linked oxidase domain protein
GRF56_10910	ENOG4105KA0	thioesterase Superfamily protein
GRF56_10915	ENOG4105C1J	atp-dependent rna helicase
GRF56_10925	ENOG4105BZU	Histidine kinase
GRF56_10930	ENOG4105D3Y	Na H antiporter
GRF56_10935	ENOG4105DH5	Responsible for the end-turnover of tRNA specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis (By similarity)
GRF56_10940	ENOG4105EYK	Phosphatidylglycerophosphatase B
GRF56_10945	ENOG4105CJ0	Catalyzes the oxidation of erythronate-4-phosphate to 3- hydroxy-2-oxo-4-phosphonooxybutanoate (By similarity)
GRF56_10950	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
GRF56_10960	ENOG4105DI7	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity)
GRF56_10965	ENOG4107QTG	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA (By similarity)
GRF56_10970	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
GRF56_10975	ENOG4108S3P	Sporulation domain protein
GRF56_10980	ENOG4105K8R	UPF0145 protein
GRF56_10990	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
GRF56_10995	ENOG410810Y	Sulfite reductase
GRF56_11000	ENOG4107SHJ	sulfite reductase subunit b
GRF56_11005	ENOG4105D5B	Sulfite reductase, subunit A
GRF56_11010	ENOG4108NRW	Phospholipase, patatin family
GRF56_11015	ENOG4105EBE	Peptidase U61, LD-carboxypeptidase A
GRF56_11020	ENOG4107T7U	Sulfatase
GRF56_11030	ENOG4105CFH	Aspartokinase
GRF56_11035	ENOG4107QZM	n-acetylglutamate synthase
GRF56_11040	ENOG4107QXP	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
GRF56_11060	ENOG4105F2Z	3-oxoadipate enol-lactonase
GRF56_11075	ENOG4105KT7	mgtC SapB transporter
GRF56_11090	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
GRF56_11105	ENOG4105C2C	drug resistance transporter, Bcr CflA
GRF56_11160	ENOG4105CHH	sulfate transporter
GRF56_11175	ENOG4105FF5	Membrane
GRF56_11185	ENOG4105JJR	Histidine kinase
GRF56_11190	ENOG4107EXC	regulatoR
GRF56_11210	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
GRF56_11215	ENOG4105VEQ	Cold shock protein
GRF56_11220	ENOG4105KAE	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation (By similarity)
GRF56_11225	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
GRF56_11230	ENOG4105K9U	however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity)
GRF56_11235	ENOG4105DWA	May conjugate Arg from its aminoacyl-tRNA to the N- termini of proteins containing an N-terminal aspartate or glutamate
GRF56_11240	ENOG4108R4Z	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine (By similarity)
GRF56_11245	ENOG4107MBR	17 kDa surface antigen
GRF56_11250	ENOG4105BZU	Histidine kinase
GRF56_11255	ENOG4105C3M	thioredoxin reductase
GRF56_11260	ENOG4105DCF	alanine dehydrogenase
GRF56_11265	ENOG4105EW9	transcriptional regulator AsnC family
GRF56_11270	ENOG4105CNU	cell division protein FtsK
GRF56_11275	ENOG4107Y7W	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) (By similarity)
GRF56_11280	ENOG4105D1H	recombination factor protein RarA
GRF56_11285	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
GRF56_11290	ENOG4105E96	Colicin v production protein
GRF56_11295	ENOG4105CBA	glutamine phosphoribosylpyrophosphate amidotransferase
GRF56_11300	ENOG4105FR9	TRNA-(Ms 2 io 6 A)-hydroxylase
GRF56_11305	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
GRF56_11310	ENOG4105CFX	Catalyzes the ferrous insertion into protoporphyrin IX (By similarity)
GRF56_11320	ENOG4107RE1	Inosine-guanosine kinase
GRF56_11335	ENOG4105BZU	Histidine kinase
GRF56_11350	ENOG4105F3T	(LipO)protein
GRF56_11360	ENOG4105QZU	Inner membrane protein YfeZ
GRF56_11365	ENOG4107QUT	magnesium and cobalt transport protein CorA
GRF56_11370	ENOG4105DWH	electron transfer flavoprotein-ubiquinone oxidoreductase
GRF56_11375	ENOG4105BZJ	Electron transfer flavoprotein
GRF56_11380	ENOG4105C10	Electron transfer flavoprotein
GRF56_11385	ENOG4107QM1	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine (By similarity)
GRF56_11390	ENOG4105CMY	5-enolpyruvylshikimate-3-phosphate synthase
GRF56_11395	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
GRF56_11400	ENOG4108NVR	Methyl-accepting chemotaxis
GRF56_11405	ENOG4105D4P	Coproporphyrinogen iii oxidase
GRF56_11410	ENOG4105C1J	atp-dependent rna helicase
GRF56_11415	ENOG4108V06	Glutathione peroxidase
GRF56_11425	ENOG4105CPF	Cell wall formation (By similarity)
GRF56_11430	ENOG4105C8I	hydrolase, family 38
GRF56_11435	ENOG4105DM4	PTS System
GRF56_11440	ENOG4105FDP	GntR family transcriptional regulator
GRF56_11445	ENOG4105DVS	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
GRF56_11450	ENOG4105DS1	cytochrome b561
GRF56_11455	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
GRF56_11460	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
GRF56_11480	ENOG4108ESY	Metal dependent phosphohydrolase
GRF56_11485	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
GRF56_11495	ENOG4105BZU	Histidine kinase
GRF56_11500	ENOG4105E3S	small subunit
GRF56_11505	ENOG4105QA4	4Fe-4S Ferredoxin, iron-sulfur binding domain protein
GRF56_11510	ENOG4105CJ5	hydrogenase 2 b cytochrome subunit
GRF56_11515	ENOG4105DPX	Hydrogenase, large subunit
GRF56_11520	ENOG4108USZ	hydrogenase
GRF56_11525	ENOG4108WGS	hydrogenase 2-specific chaperone
GRF56_11535	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
GRF56_11540	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
GRF56_11545	ENOG4105C3U	ABC transporter
GRF56_11550	ENOG4105EFJ	Part of the ABC transporter complex NikABCDE involved in nickel import. Responsible for energy coupling to the transport system (By similarity)
GRF56_11555	ENOG4107RSS	Hydrogenase accessory protein HypB
GRF56_11560	ENOG4105WMM	Probably plays a role in a hydrogenase nickel cofactor insertion step (By similarity)
GRF56_11565	ENOG4105C45	hydrogenase expression formation protein (HypE)
GRF56_11570	ENOG4105CQS	hydrogenase expression formation protein HypD
GRF56_11575	ENOG4105WRB	Hydrogenase assembly chaperone hypC hupF
GRF56_11585	ENOG4105EM7	Selenocysteine-specific translation elongation factor
GRF56_11590	ENOG4105C1Y	Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis (By similarity)
GRF56_11600	ENOG4108MG9	hydrogenase 3 maturation protease
GRF56_11605	ENOG4105I6X	formate hydrogenlyase maturation
GRF56_11610	ENOG4105C47	NADH ubiquinone oxidoreductase 20 kda subunit
GRF56_11620	ENOG4105CQV	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
GRF56_11625	ENOG4107TDF	Formate hydrogenlyase subunit 4
GRF56_11630	ENOG4108JPZ	Monovalent cation H antiporter subunit D
GRF56_11635	ENOG4108MFN	small subunit of hydrogenase-3, iron-sulfur protein (part of formate hydrogenlyase (FHL) complex)
GRF56_11640	ENOG4105DFH	Transport of potassium into the cell (By similarity)
GRF56_11645	ENOG4105ESI	atpase involved in dna repair
GRF56_11650	ENOG4108RC0	Electron transport protein
GRF56_11670	ENOG4107H9G	Necessary for formate dehydrogenase activity (By similarity)
GRF56_11675	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
GRF56_11685	ENOG4105MWK	D-amino acid dehydrogenase, small subunit
GRF56_11690	ENOG4105EXX	Deoxyribodipyrimidine photolyase-related protein
GRF56_11700	ENOG4105C0F	tryptophanase EC 4.1.99.1
GRF56_11705	ENOG4107T42	This enzyme scavenge exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis (By similarity)
GRF56_11710	ENOG41067MG	lrgb family
GRF56_11720	ENOG4107R49	K07407 alpha-galactosidase EC 3.2.1.22
GRF56_11730	ENOG4105CJB	Exodeoxyribonuclease I
GRF56_11735	ENOG4105DFP	Integrase
GRF56_11790	ENOG4105YQ0	
GRF56_11965	ENOG4105CAR	Terminase, large subunit
GRF56_11980	ENOG4105D07	Signal peptide peptidase, SppA
GRF56_12070	ENOG4105C4X	radical SAM domain protein
GRF56_12095	ENOG4107QVM	von Willebrand factor, type A
GRF56_12115	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
GRF56_12120	ENOG4105ENH	Sulfatase
GRF56_12125	ENOG4105DHT	Metal Dependent Phosphohydrolase
GRF56_12135	ENOG4105CQ7	ATP-dependent helicase
GRF56_12145	ENOG4105KW6	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance (By similarity)
GRF56_12155	ENOG4105CHU	acetyl-coa acetyltransferase
GRF56_12160	ENOG4105D58	Diguanylate phosphodiesterase
GRF56_12165	ENOG4105CKF	membrane protein involved in aromatic hydrocarbon degradation
GRF56_12170	ENOG4105CKF	membrane protein involved in aromatic hydrocarbon degradation
GRF56_12180	ENOG4105EMN	RNA polymerase sigma factor
GRF56_12210	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
GRF56_12215	ENOG4105CHU	acetyl-coa acetyltransferase
GRF56_12220	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
GRF56_12225	ENOG4105ED1	spovr family
GRF56_12230	ENOG4106AKX	UPF0229 protein
GRF56_12235	ENOG4105CYN	Serine protein kinase
GRF56_12240	ENOG4105C9U	ATP-dependent DNA helicase RecQ
GRF56_12245	ENOG4107QV7	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system) (By similarity)
GRF56_12255	ENOG4105C44	Serine transporter
GRF56_12260	ENOG4105P8F	nudix hydrolase
GRF56_12275	ENOG4108Z8G	Alkylphosphonate utilization operon protein PhnA
GRF56_12290	ENOG4105CVJ	phosphoglycerate mutase
GRF56_12295	ENOG4105BZU	Histidine kinase
GRF56_12300	ENOG4108DG9	Smr protein MutS2
GRF56_12305	ENOG4105C76	Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue (By similarity)
GRF56_12310	ENOG4105D10	5-enolpyruvylshikimate-3-phosphate phospholyase
GRF56_12320	ENOG4105C1J	atp-dependent rna helicase
GRF56_12330	ENOG4105WJG	Glutathione
GRF56_12340	ENOG4105E0U	tyrosine-specific transport protein
GRF56_12345	ENOG4107B7Y	DNA-binding transcriptional regulator FruR
GRF56_12350	ENOG4105DTZ	bifunctional PTS system fructose-specific transporter subunit IIA HPr protein
GRF56_12355	ENOG4105DE4	1-phosphofructokinase
GRF56_12360	ENOG4105DM4	PTS System
GRF56_12365	ENOG4105XZD	Fe-S protein
GRF56_12370	ENOG4105CA3	membrane-bound lytic murein transglycosylase
GRF56_12375	ENOG4105XPH	Ferredoxin
GRF56_12380	ENOG4105E05	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
GRF56_12385	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
GRF56_12390	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
GRF56_12395	ENOG4108HWB	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
GRF56_12400	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
GRF56_12420	ENOG4105C22	threonyL-tRNA synthetase
GRF56_12425	ENOG4108UUX	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity)
GRF56_12435	ENOG4108YZX	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity)
GRF56_12440	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
GRF56_12445	ENOG4105C6A	phenylalanyl-tRNA synthetase (beta subunit)
GRF56_12450	ENOG4108ZUF	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
GRF56_12455	ENOG4105BZU	Histidine kinase
GRF56_12470	ENOG4105NDF	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity)
GRF56_12480	ENOG4108KHX	Diguanylate cyclase
GRF56_12485	ENOG4105ETE	Transcriptional regulator (LacI family
GRF56_12490	ENOG4108RVA	ribokinase
GRF56_12495	ENOG4105E9V	Periplasmic binding protein LacI transcriptional regulator
GRF56_12500	ENOG4105CNN	ABC, transporter
GRF56_12505	ENOG4105C2J	ABC transporter
GRF56_12510	ENOG4105MRB	Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose (By similarity)
GRF56_12515	ENOG4108K3A	Glutathione S-transferase
GRF56_12525	ENOG4107RUE	extracellular solute-binding protein family 1
GRF56_12530	ENOG4105D38	putrescine abc transporter
GRF56_12535	ENOG4105F38	ABC transporter, permease
GRF56_12555	ENOG4105CB3	Required for the thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32) (By similarity)
GRF56_12560	ENOG4105Q9Y	Universal stress protein
GRF56_12565	ENOG4105DS0	Transcriptional regulator, Crp Fnr family
GRF56_12580	ENOG4105C59	p-type ATPase
GRF56_12590	ENOG4105D6P	C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex (By similarity)
GRF56_12605	ENOG4105EUH	cytochrome C oxidase, cbb3-type, subunit i
GRF56_12615	ENOG4108ZGC	gaf domain protein
GRF56_12620	ENOG41073DY	may be a structural element that influences the osmotic activation of ProP at a post-translational level (By similarity)
GRF56_12625	ENOG4105CN1	protease
GRF56_12630	ENOG4105CD8	aminopeptidase N
GRF56_12640	ENOG4105C7I	Dehydrogenase
GRF56_12645	ENOG4107QYT	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor (By similarity)
GRF56_12650	ENOG4108T7E	Contributes to the efficiency of the cell division process by stabilizing the polymeric form of the cell division protein FtsZ. Acts by promoting interactions between FtsZ protofilaments and suppressing the GTPase activity of FtsZ (By similarity)
GRF56_12660	ENOG4105NRA	50s ribosomal protein l31 type b
GRF56_12670	ENOG4105C4H	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA (By similarity)
GRF56_12680	ENOG4105C5H	ABC transporter
GRF56_12685	ENOG4105WFT	During stationary phase, converts 70S ribosomes to an inactive dimeric form (100S ribosomes) (By similarity)
GRF56_12690	ENOG4108RKI	Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl- ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)- decenoyl-ACP. Can catalyze the dehydratase reaction for beta- hydroxyacyl-ACPs with saturated chain lengths up to 16 0, being most active on intermediate chain length (By similarity)
GRF56_12695	ENOG4105DAN	ATP-dependent protease
GRF56_12725	ENOG4105X2V	dna damage-inducible protein
GRF56_12730	ENOG4108KTS	Acetyltransferase and hydrolase with the alpha beta hydrolase fold
GRF56_12735	ENOG4105PDP	Short chain dehydrogenase
GRF56_12775	ENOG4105DXD	2-methylcitrate dehydratase
GRF56_12780	ENOG4105BZN	citrate synthase
GRF56_12785	ENOG4105CR4	methylisocitrate lyase
GRF56_12790	ENOG4105F1S	paraquat-inducible protein a
GRF56_12795	ENOG4105F1S	paraquat-inducible protein a
GRF56_12800	ENOG4105DY2	Paraquat-inducible protein b
GRF56_12805	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
GRF56_12820	ENOG4105F8V	Hydrolase, tatD family
GRF56_12825	ENOG4107QRG	dna polymerase iii
GRF56_12830	ENOG4108ZMD	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity)
GRF56_12835	ENOG4105HHA	aminodeoxychorismate lyase
GRF56_12840	ENOG4105YAZ	4-amino-4-deoxychorismate lyase
GRF56_12845	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
GRF56_12850	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
GRF56_12855	ENOG4105CHR	reductase
GRF56_12860	ENOG4105CJF	Malonyl coA-acyl carrier protein transacylase
GRF56_12865	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
GRF56_12870	ENOG4105C6B	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA (By similarity)
GRF56_12875	ENOG4105VGS	50s ribosomal protein l32
GRF56_12880	ENOG4105FCQ	metal-binding, possibly nucleic acid-binding protein
GRF56_12885	ENOG4108UHJ	MAF-like protein
GRF56_12895	ENOG4105EI2	Pseudouridine synthase
GRF56_12900	ENOG4105C03	ribonuclease
GRF56_12910	ENOG4105CJ3	phosphate transporter
GRF56_12915	ENOG4105DHP	deoxycytidine triphosphate deaminase
GRF56_12920	ENOG4105DBI	uridine monophosphokinase
GRF56_12925	ENOG4105D1F	ATP-binding protein
GRF56_12930	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
GRF56_12940	ENOG4105VSY	K01512 acylphosphatase EC 3.6.1.7
GRF56_12945	ENOG4108N3W	hemolysin secretion protein
GRF56_12950	ENOG4105DR4	Methyltransferase
GRF56_12955	ENOG4105FAT	Acyl-transferase
GRF56_12965	ENOG4105D4F	Synthesizes selenophosphate from selenide and ATP (By similarity)
GRF56_12970	ENOG4105CR7	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA (By similarity)
GRF56_12975	ENOG4105C5X	domain protein
GRF56_12985	ENOG4105CEY	Amp-dependent synthetase and ligase
GRF56_12990	ENOG4108MXF	Alpha Beta Hydrolase
GRF56_13000	ENOG41072GX	Peptidase M22 Glycoprotease
GRF56_13005	ENOG4105DVT	helicase
GRF56_13015	ENOG4105E21	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity)
GRF56_13020	ENOG4105CEK	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity)
GRF56_13025	ENOG4105CIH	Imidazole acetol-phosphate transaminase
GRF56_13030	ENOG4105ECC	imidazole-glycerol-phosphate dehydratase
GRF56_13035	ENOG4108UJE	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity)
GRF56_13040	ENOG4105CJV	Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase
GRF56_13045	ENOG4105C0S	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity)
GRF56_13050	ENOG4105K8F	Phosphoribosyl-amp cyclohydrolase
GRF56_13060	ENOG4105BZU	Histidine kinase
GRF56_13065	ENOG4105CEY	Amp-dependent synthetase and ligase
GRF56_13070	ENOG4105CSX	c4-dicarboxylate anaerobic carrier
GRF56_13080	ENOG4107MBR	17 kDa surface antigen
GRF56_13085	ENOG4108UTP	(2Fe-2S)-binding domain protein
GRF56_13090	ENOG4108HR6	Dehydrogenase
GRF56_13095	ENOG4105C7W	Xanthine dehydrogenase
GRF56_13100	ENOG4105C7N	Xanthine uracil vitamin C permease
GRF56_13105	ENOG4107QUY	Guanine deaminase
GRF56_13110	ENOG4105C2W	permease
GRF56_13115	ENOG4105C7W	Xanthine dehydrogenase
GRF56_13120	ENOG410873Y	FAD binding domain in molybdopterin dehydrogenase
GRF56_13125	ENOG4107UUR	Chlorohydrolase aminohydrolase
GRF56_13130	ENOG4105BZ8	glutamate synthase
GRF56_13140	ENOG4105MFX	4-diphosphocytidyl-2c-methyl-d-erythritol synthase
GRF56_13145	ENOG4105MJ6	selenium-dependent hydroxylase accessory protein YqeC
GRF56_13150	ENOG4107P0T	Selenium-dependent molybdenum hydroxylase system protein, YqeB family
GRF56_13155	ENOG4108Q5Y	Membrane
GRF56_13160	ENOG4105C5B	carbamate kinase
GRF56_13170	ENOG4107S4Y	M20 DapE family protein YgeY
GRF56_13175	ENOG4107RCH	Diaminopropionate ammonia-lyase
GRF56_13180	ENOG4105IW6	Carbamoyltransferase
GRF56_13215	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
GRF56_13235	ENOG4105DUC	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division (By similarity)
GRF56_13240	ENOG4105DAH	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF (By similarity)
GRF56_13245	ENOG4105GHU	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid partitioning. Probably acts via its interaction with MukB and MukE. Overexpression results in anucleate cells. It has a calcium binding activity (By similarity)
GRF56_13250	ENOG4106371	Methyltransferase
GRF56_13255	ENOG4107S90	membrAne
GRF56_13265	ENOG4105CTQ	phosphohexokinase
GRF56_13270	ENOG4105CK2	sodium dicarboxylate symporter
GRF56_13275	ENOG4105NBK	UPF0345 protein
GRF56_13280	ENOG4105EJQ	L-serine dehydratase
GRF56_13285	ENOG4105EJQ	L-serine dehydratase
GRF56_13290	ENOG4105VNG	YcgL domain-containing protein
GRF56_13295	ENOG4105K7U	Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization (By similarity)
GRF56_13300	ENOG4107QMS	site-determining protein
GRF56_13305	ENOG4105VJP	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell (By similarity)
GRF56_13315	ENOG4108VKV	Monofunctional biosynthetic peptidoglycan transglycosylase
GRF56_13320	ENOG4105XW2	UPF0263 protein
GRF56_13355	ENOG4108V3G	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity)
GRF56_13360	ENOG4108SXK	Transporter Drug Metabolite Exporter family
GRF56_13365	ENOG4108HH9	Catalyzes two reactions the first one is the production of beta-formyl glycinamide ribonucleotide (GAR) from formate, ATP and beta GAR
GRF56_13370	ENOG4107UW8	HAD-superfamily hydrolase subfamily IA variant 3
GRF56_13380	ENOG4108R6K	riboflavin synthase, subunit alpha
GRF56_13390	ENOG4105W1I	UPF0253 protein
GRF56_13395	ENOG4107QI1	Mate efflux family protein
GRF56_13425	ENOG4108JUB	Transcriptional regulator
GRF56_13440	ENOG4108VWS	Yaeq family
GRF56_13455	ENOG4105DKR	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity)
GRF56_13460	ENOG410635M	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein (By similarity)
GRF56_13465	ENOG4105DQR	SNARE associated Golgi
GRF56_13475	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
GRF56_13490	ENOG4105D0C	transport protein
GRF56_13495	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
GRF56_13500	ENOG4105CWG	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34 (By similarity)
GRF56_13515	ENOG4105CEE	C4-dicarboxylate transporter
GRF56_13530	ENOG4108VKG	metal-dependent hydrolase
GRF56_13545	ENOG4105CQ2	DNA polymerase
GRF56_13555	ENOG4105BZU	Histidine kinase
GRF56_13570	ENOG4105D1S	lipid A biosynthesis
GRF56_13575	ENOG4105NWR	lipid A biosynthesis (Kdo)2-(Lauroyl)-lipid IVA acyltransferase
GRF56_13585	ENOG4105DUM	transcriptional regulator, lysR family
GRF56_13590	ENOG4105EFU	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin (By similarity)
GRF56_13595	ENOG4105KDX	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection (By similarity)
GRF56_13600	ENOG4107QMP	dna polymerase iii subunits gamma and tau
GRF56_13605	ENOG4109003	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity)
GRF56_13610	ENOG4105WD1	Membrane
GRF56_13615	ENOG4105FBT	Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs (By similarity)
GRF56_13630	ENOG4105PAD	Hydrolase
GRF56_13635	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
GRF56_13685	ENOG4105CPB	ATP-dependent endonuclease of the OLD family
GRF56_13700	ENOG4105VP0	transcriptional regulator, lysR family
GRF56_13705	ENOG4105EJ9	Membrane
GRF56_13710	ENOG4106IUH	DTW domain containing protein
GRF56_13715	ENOG4105E2R	ROK family
GRF56_13720	ENOG4105C8Q	Methyl-accepting chemotaxis
GRF56_13725	ENOG4105K5B	UPF0225 protein
GRF56_13730	ENOG4107R5Y	anaerobic glycerol-3-phosphate dehydrogenase, subunit A
GRF56_13735	ENOG4108KJ0	anaerobic glycerol-3-phosphate dehydrogenase, subunit B
GRF56_13740	ENOG4105CHG	glycolate oxidase (iron-sulfur subunit)
GRF56_13750	ENOG4105JJ8	Cytochrome c nitrite reductase, pentaheme subunit
GRF56_13755	ENOG4105D3S	4Fe-4S Ferredoxin, iron-sulfur binding domain protein
GRF56_13760	ENOG4105DVI	reductase, NrfD
GRF56_13765	ENOG4105DA4	cytochrome c-type biogenesis protein
GRF56_13770	ENOG4107QX9	Thiol disulfide interChange protein
GRF56_13775	ENOG4108DMF	Cytochrome C biogenesis protein
GRF56_13790	ENOG4108KAZ	Involved in phosphonate degradation (By similarity)
GRF56_13795	ENOG4108JPW	Aminotransferase
GRF56_13800	ENOG4107STF	Involved in phosphonate degradation (By similarity)
GRF56_13810	ENOG4105C4Y	ABC transporter
GRF56_13820	ENOG4107RCV	ABC transporter, permease
GRF56_13825	ENOG4105CJP	fad dependent oxidoreductase
GRF56_13840	ENOG4105CH8	Succinyl-CoA ligase ADP-forming subunit alpha
GRF56_13845	ENOG4105CMV	Succinyl-CoA synthetase subunit beta
GRF56_13850	ENOG4105C7S	Dehydrogenase
GRF56_13855	ENOG4105C7P	2-oxoglutarate dehydrogenase, E1
GRF56_13860	ENOG4105E33	succinate dehydrogenase
GRF56_13865	ENOG4105C00	Succinate dehydrogenase (Flavoprotein subunit)
GRF56_13870	ENOG4105N1I	succinate dehydrogenase, hydrophobic membrane anchor protein
GRF56_13875	ENOG4108UTY	succinate dehydrogenase, cytochrome b556 subunit
GRF56_13885	ENOG4105BZN	citrate synthase
GRF56_13895	ENOG4105K5X	acetyltransferase
GRF56_13925	ENOG4107XGF	functions in a salvage pathway. Uses pyridoxamine (By similarity)
GRF56_13940	ENOG4105WQ3	Rna-binding protein
GRF56_13950	ENOG4105BZ1	(ABC) transporter
GRF56_13955	ENOG4105BZ1	(ABC) transporter
GRF56_13960	ENOG4105BZU	Histidine kinase
GRF56_13965	ENOG4105K63	Thioredoxin
GRF56_13970	ENOG4105C8P	)-transporter
GRF56_13975	ENOG4107QQN	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties (By similarity)
GRF56_13990	ENOG4108IPJ	Membrane
GRF56_14000	ENOG4108BY2	phosphohistidine phosphatase
GRF56_14005	ENOG4107QXK	peptidase
GRF56_14010	ENOG4105FQ6	thiopurine methyltransferase
GRF56_14025	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
GRF56_14050	ENOG4105HF0	Membrane
GRF56_14055	ENOG4105D5Q	Arginine ornithine antiporter
GRF56_14060	ENOG4105CHR	reductase
GRF56_14065	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
GRF56_14070	ENOG4105E39	Enoyl-CoA hydratase
GRF56_14075	ENOG4105E39	Enoyl-CoA hydratase
GRF56_14080	ENOG4105C1G	acyl-Coa dehydrogenase
GRF56_14085	ENOG4105C1G	acyl-Coa dehydrogenase
GRF56_14090	ENOG4107QX3	carboxylase
GRF56_14095	ENOG4105E39	Enoyl-CoA hydratase
GRF56_14105	ENOG4105CBH	Hydroxymethylglutaryl-CoA lyase
GRF56_14125	ENOG4106HK8	GPR1 FUN34 yaaH family protein
GRF56_14140	ENOG4105BZG	amino acid carrier protein
GRF56_14145	ENOG41060WC	Enoyl-CoA hydratase
GRF56_14160	ENOG41062QD	Membrane
GRF56_14165	ENOG4107QN1	sodium solute
GRF56_14170	ENOG4105C5H	ABC transporter
GRF56_14175	ENOG4105EIN	peptidylprolyl cis-trans isomerase
GRF56_14180	ENOG4105K70	DNA-binding protein
GRF56_14185	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
GRF56_14190	ENOG4105CHN	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
GRF56_14195	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
GRF56_14200	ENOG4105DEA	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation
GRF56_14215	ENOG4105D60	lipoprotein releasing system transmembrane protein
GRF56_14220	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
GRF56_14225	ENOG4105D60	lipoprotein releasing system transmembrane protein
GRF56_14240	ENOG4105CZI	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
GRF56_14245	ENOG4108J59	Extracellular solute-binding protein, family 5
GRF56_14255	ENOG4105C6N	Formate acetyltransferase
GRF56_14260	ENOG4105TMB	Formate nitrite transporter
GRF56_14265	ENOG4105DDY	UPF0142 protein ycaO
GRF56_14270	ENOG4105CS2	ec 3.2.1.21
GRF56_14275	ENOG4108KB2	LysR family Transcriptional regulator
GRF56_14285	ENOG4105DSS	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation (By similarity)
GRF56_14290	ENOG4105DZ2	Transcriptional regulator
GRF56_14295	ENOG4105EXG	Transcriptional regulator
GRF56_14300	ENOG4105CHJ	isochorismatase hydrolase
GRF56_14305	ENOG4105EUB	pirin domain protein
GRF56_14310	ENOG4105DJB	Major Facilitator Superfamily
GRF56_14315	ENOG41064T2	transcriptional regulator, lysR family
GRF56_14320	ENOG4105CR8	Transcriptional regulator
GRF56_14325	ENOG4108RYK	Nad-dependent epimerase dehydratase
GRF56_14335	ENOG4105C28	cystathionine
GRF56_14345	ENOG4105MH2	YfcL protein
GRF56_14355	ENOG4105EE5	Membrane protein terC
GRF56_14360	ENOG41090EK	ompa motb domain protein
GRF56_14365	ENOG4108KHX	Diguanylate cyclase
GRF56_14385	ENOG41090A4	Pterin carbinolamine dehydratase
GRF56_14390	ENOG4105MIR	Phenylalanine 4-monooxygenase
GRF56_14395	ENOG4106K28	UPF0283 membrane protein
GRF56_14400	ENOG4105CM6	amino acid regulated cytosolic protein
GRF56_14410	ENOG4105YYT	phage shock protein B
GRF56_14415	ENOG41087YS	Phage shock protein A
GRF56_14420	ENOG4105E51	psp operon transcriptional activator
GRF56_14425	ENOG4108J59	Extracellular solute-binding protein, family 5
GRF56_14430	ENOG4108I5W	peptide transport system, permease protein
GRF56_14435	ENOG4108EU3	peptide transport system, permease
GRF56_14440	ENOG4108JQ3	Peptide ABC transporter ATP-binding protein
GRF56_14445	ENOG4108JQ2	peptide transport system atp-binding protein
GRF56_14450	ENOG4105CJX	Molecular chaperone. Has ATPase activity (By similarity)
GRF56_14455	ENOG4105F3K	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity)
GRF56_14465	ENOG4108RMJ	sensory transduction regulator
GRF56_14475	ENOG4107104	thymidine kinase
GRF56_14480	ENOG4107S6Z	Na H antiporter
GRF56_14490	ENOG4108WBT	adenosyltransferase
GRF56_14495	ENOG4105VRT	cytoplasmic protein
GRF56_14500	ENOG4105EIZ	Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity)
GRF56_14505	ENOG4105FD2	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) (By similarity)
GRF56_14520	ENOG4106EG9	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) (By similarity)
GRF56_14525	ENOG4105CFV	Tetratricopeptide repeat protein
GRF56_14535	ENOG41080YA	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
GRF56_14540	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
GRF56_14545	ENOG4105CAT	Cytidine monophosphate kinase
GRF56_14550	ENOG4108JEN	Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate (By similarity)
GRF56_14555	ENOG4107R11	Transcriptional regulator
GRF56_14560	ENOG4105DUM	transcriptional regulator, lysR family
GRF56_14565	ENOG4108SC4	)-transporter
GRF56_14580	ENOG4108DBC	nitroreductase
GRF56_14585	ENOG4105CFC	Transporter
GRF56_14590	ENOG4105BZU	Histidine kinase
GRF56_14595	ENOG4105CBN	LysR family transcriptional regulator
GRF56_14600	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
GRF56_14615	ENOG4108RU0	short-chain dehydrogenase reductase
GRF56_14625	ENOG4107RGM	aldo keto reductase
GRF56_14630	ENOG4105VFU	Rna-binding protein
GRF56_14640	ENOG4105CDA	abc transporter atp-binding protein
GRF56_14645	ENOG4105EAD	ABC transporter
GRF56_14650	ENOG4106TNF	Periplasmic binding protein
GRF56_14655	ENOG4105EZ7	amino acid ABC transporter
GRF56_14660	ENOG4105HPZ	Involved in the removal of murein from the sacculus. May also facilitate integration of nascent murein strands into the sacculus by cleaving the peptide bonds between neighboring strands in mature murein (By similarity)
GRF56_14670	ENOG4105HA9	of methanol dehydrogenase type
GRF56_14685	ENOG4105E14	MotA TolQ exbB proton channel
GRF56_14690	ENOG4105ER2	Ompa motb domain protein
GRF56_14695	ENOG4105D05	Receptor
GRF56_14700	ENOG4105CUG	Oligopeptidase b
GRF56_14720	ENOG4105KWU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
GRF56_14725	ENOG4105ES3	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
GRF56_14730	ENOG4105CQV	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
GRF56_14735	ENOG4105GKE	subunit e
GRF56_14740	ENOG4107QIZ	NADH dehydrogenase
GRF56_14745	ENOG4108IEH	NADH dehydrogenase subunit g
GRF56_14750	ENOG4105CMZ	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone (By similarity)
GRF56_14755	ENOG4105P3U	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
GRF56_14760	ENOG4107UFS	subunit j
GRF56_14765	ENOG41080EA	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
GRF56_14770	ENOG4105D65	subunit l
GRF56_14775	ENOG4105C8S	subunit m
GRF56_14780	ENOG4105CNR	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
GRF56_14790	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
GRF56_14795	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
GRF56_14800	ENOG4107QIK	phosphoribosylformylglycinamidine synthase
GRF56_14805	ENOG4105CHQ	Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella (By similarity)
GRF56_14810	ENOG4105VPD	cellular component movement
GRF56_14815	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
GRF56_14820	ENOG4105CNE	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
GRF56_14825	ENOG4105N21	Membrane
GRF56_14830	ENOG4105CUT	histidyl-tRNA synthetase
GRF56_14835	ENOG4105C4E	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (By similarity)
GRF56_14840	ENOG4105HSZ	Cytoskeletal protein that is involved in cell-shape control through regulation of the length of the long axis (By similarity)
GRF56_14850	ENOG4105C55	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
GRF56_14855	ENOG4108UGX	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity)
GRF56_14870	ENOG4108ZIT	Ferredoxin, 2FE-2S
GRF56_14875	ENOG4105C9I	Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB
GRF56_14880	ENOG4108SWN	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA (By similarity)
GRF56_14885	ENOG4108Z4V	iron-sulfur cluster assembly
GRF56_14890	ENOG4107XTC	May be involved in the formation or repair of Fe-S clusters present in iron-sulfur proteins
GRF56_14895	ENOG4105C3J	Cysteine desulfurase
GRF56_14900	ENOG4108ZF1	Transcriptional regulator, BadM Rrf2 family
GRF56_14905	ENOG4105CVS	RNA methyltransferase TrmH family, group 1
GRF56_14915	ENOG4105XPQ	lipid carrier protein
GRF56_14920	ENOG4105CFP	Peptidase U32
GRF56_14925	ENOG4106RZ4	Peptidase U32
GRF56_14945	ENOG4107RAB	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
GRF56_14950	ENOG4107QN8	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
GRF56_14955	ENOG4105VIE	preprotein translocase, subunit YajC
GRF56_14960	ENOG4105C6U	Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity)
GRF56_14965	ENOG4105E2N	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) (By similarity)
GRF56_14970	ENOG4105W87	Cbs domain
GRF56_14975	ENOG4105D3R	alkyl hydroperoxide reductase
GRF56_15015	ENOG4105C42	Type I secretion membrane fusion protein (HlyD
GRF56_15020	ENOG4108JJA	ABC, transporter
GRF56_15025	ENOG4105N5T	Radical SAM Protein
GRF56_15030	ENOG4105CBC	glutamate synthase
GRF56_15035	ENOG4105BZ8	glutamate synthase
GRF56_15045	ENOG4105C1J	atp-dependent rna helicase
GRF56_15070	ENOG4108ZJT	translation initiation factor, Sui1
GRF56_15125	ENOG4108R5K	PPIases accelerate the folding of proteins (By similarity)
GRF56_15135	ENOG4105F10	Catalyzes the hydrolysis of the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1- phosphate (lipid X) and UMP (By similarity)
GRF56_15145	ENOG4105Y3U	Transglycosylase-associated protein
GRF56_15150	ENOG4105DHQ	Histidine kinase
GRF56_15195	ENOG4105CII	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity)
GRF56_15200	ENOG4105WH1	Two component transcriptional regulator luxr family
GRF56_15205	ENOG4105CET	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria (By similarity)
GRF56_15210	ENOG4105W49	UPF0434 protein
GRF56_15215	ENOG4105CHD	Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) (By similarity)
GRF56_15225	ENOG4108EQH	DNA internalization-related competence protein ComEC Rec2
GRF56_15240	ENOG4105CGF	Aromatic amino acid aminotransferase
GRF56_15250	ENOG4105CVI	Transcriptional regulator
GRF56_15255	ENOG4108WFC	UPF0438 protein yifE
GRF56_15260	ENOG4108QSZ	General inhibitor of pancreatic serine proteases inhibits chymotrypsin, trypsin, elastases, factor X, kallikrein as well as a variety of other proteases (By similarity)
GRF56_15265	ENOG4106MZZ	glycerophosphoryl diester phosphodiesterase
GRF56_15270	ENOG4105C6V	Glycerol-3-phosphate dehydrogenase
GRF56_15275	ENOG4105E98	transcriptional regulator DeoR family
GRF56_15280	ENOG4105CXY	transporter
GRF56_15285	ENOG4105D8C	Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity)
GRF56_15290	ENOG4108JQ0	Key enzyme in the regulation of glycerol uptake and metabolism (By similarity)
GRF56_15295	ENOG41069D7	Methyl-accepting chemotaxis
GRF56_15305	ENOG4105HEI	LysR family (Transcriptional regulator
GRF56_15320	ENOG4105CV8	reductase
GRF56_15330	ENOG4105F27	Major Facilitator
GRF56_15335	ENOG4108X0B	nad(p)h dehydrogenase (quinone)
GRF56_15350	ENOG4105E18	UPF0276 protein
GRF56_15370	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
GRF56_15375	ENOG4105C4M	(Ubiquinol oxidase) subunit I
GRF56_15380	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
GRF56_15390	ENOG4108Q2J	Inner membrane protein YebE
GRF56_15395	ENOG4105NAU	thioesterase Superfamily protein
GRF56_15400	ENOG4106428	Protein of unknown function (DUF2496)
GRF56_15415	ENOG4105DJ2	Major Facilitator Superfamily
GRF56_15420	ENOG4105FE9	pseudouridine synthase
GRF56_15430	ENOG4105I9P	Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor (By similarity)
GRF56_15440	ENOG4108R4U	Hnh endonuclease
GRF56_15445	ENOG4105DGN	Electron transport complex
GRF56_15450	ENOG4108R3D	Electron transport complex
GRF56_15460	ENOG4105D6A	Electron transport complex
GRF56_15470	ENOG4105DZB	Electron transport complex
GRF56_15475	ENOG4105CSM	endonuclease III
GRF56_15480	ENOG4108UYE	Lactoylglutathione lyase
GRF56_15485	ENOG4105EIY	sodium-type flagellar protein motY
GRF56_15515	ENOG4107QS8	(LipO)protein
GRF56_15520	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
GRF56_15525	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
GRF56_15530	ENOG4105DUK	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity)
GRF56_15545	ENOG4105MK2	5-formyltetrahydrofolate cyclo-ligase
GRF56_15550	ENOG4105E66	phosphoriboisomerase A
GRF56_15555	ENOG4108JQ1	Dehydrogenase
GRF56_15560	ENOG41080IJ	Diacylglycerol kinase
GRF56_15565	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
GRF56_15575	ENOG41080WI	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system (By similarity)
GRF56_15580	ENOG4108ESU	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Involved in the translocation of the substrate across the membrane (By similarity)
GRF56_15595	ENOG4105CZX	twitching motility protein
GRF56_15605	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
GRF56_15610	ENOG4105DU1	integral membrane protein, terc
GRF56_15615	ENOG4108JQ7	(ABC) transporter
GRF56_15620	ENOG4105C3U	ABC transporter
GRF56_15625	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
GRF56_15630	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
GRF56_15635	ENOG4107QSI	ABC, transporter
GRF56_15640	ENOG4105EZI	multiple antibiotic resistance (MarC)-related protein
GRF56_15645	ENOG4108EKI	Dehydrogenase
GRF56_15660	ENOG4105CDY	transcriptional regulatory protein
GRF56_15665	ENOG4105C9M	aspartyl-trna synthetase
GRF56_15675	ENOG41081XQ	Conserved Protein
GRF56_15680	ENOG4105DA6	Catalyzes the conversion of 5-methoxyuridine (mo5U) to uridine-5-oxyacetic acid (cmo5U) at position 34 in tRNA. May also participate in the methylation of uridine-5-oxyacetic acid (cmo5U) to uridine-5-oxyacetic acid methyl ester (mcmo5U) (By similarity)
GRF56_15685	ENOG4105PFA	Catalyzes the conversion of 5-hydroxyuridine (ho5U) to 5-methoxyuridine (mo5U) at position 34 in tRNA (By similarity)
GRF56_15705	ENOG4105D3R	alkyl hydroperoxide reductase
GRF56_15710	ENOG4105C5Q	Transcriptional regulator
GRF56_15715	ENOG4108QBX	(LipO)protein
GRF56_15725	ENOG4105W8I	Transcriptional regulator
GRF56_15735	ENOG4105BZC	d-serine deaminase
GRF56_15745	ENOG4108HMX	isocitrate dehydrogenase (NADP)
GRF56_15750	ENOG4108CIP	transcriptional regulator
GRF56_15755	ENOG4105EIP	mannose-6-phosphate isomerase
GRF56_15760	ENOG4105CWX	Alpha-1,2-mannosidase
GRF56_15775	ENOG4105CWX	Alpha-1,2-mannosidase
GRF56_15780	ENOG4105DM4	PTS System
GRF56_15795	ENOG4105KAF	membrAne
GRF56_15825	ENOG4107RGH	Aldehyde dehydrogenase
GRF56_15830	ENOG4107Z3H	Transcriptional regulator, TetR family
GRF56_15860	ENOG4105UQX	Mate efflux family protein
GRF56_15870	ENOG4105Z2P	Protein of unknown function (DUF465)
GRF56_15880	ENOG4105BZU	Histidine kinase
GRF56_15885	ENOG4108YXG	UPF0502 protein
GRF56_15915	ENOG4105CGK	Exodeoxyribonuclease III
GRF56_15940	ENOG4105EP1	Efflux transporter rnd family, mfp subunit
GRF56_15945	ENOG4108IJF	Heavy metal efflux pump, CzcA
GRF56_15955	ENOG4105S10	periplasmic binding protein
GRF56_15960	ENOG4105E0A	ABC, transporter
GRF56_15965	ENOG4105TVJ	transport system, permease
GRF56_15970	ENOG4105DQ5	transport system permease protein
GRF56_15975	ENOG4105D05	Receptor
GRF56_15980	ENOG4105Q26	Siderophore-interacting protein
GRF56_15985	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
GRF56_15995	ENOG4107RZZ	dna polymerase iii epsilon subunit
GRF56_16000	ENOG4108UMW	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
GRF56_16005	ENOG4105D1A	Methyltransferase
GRF56_16010	ENOG4108RW0	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
GRF56_16015	ENOG4105E9H	Lytic Murein transglycosylase
GRF56_16030	ENOG4105KR1	Trans-acting protein required for termination of DNA replication. Binds to DNA replication terminator sequences (terA to terF) to prevent the passage of replication forks. The termination efficiency will be affected by the affinity of this protein for the terminator sequence (By similarity)
GRF56_16040	ENOG4105BZU	Histidine kinase
GRF56_16045	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
GRF56_16050	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
GRF56_16055	ENOG4105BZS	acriflavin resistance protein
GRF56_16065	ENOG4107N1Q	ErfK YbiS YcfS YnhG family protein
GRF56_16075	ENOG4105C8P	)-transporter
GRF56_16085	ENOG4105EBA	Specifically methylates the adenine in position 1618 of 23S rRNA (By similarity)
GRF56_16090	ENOG4107TT5	NLP P60 protein
GRF56_16095	ENOG4107YAK	holo-(acyl carrier protein) synthase 2
GRF56_16100	ENOG4105K63	Thioredoxin
GRF56_16110	ENOG4105C66	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity)
GRF56_16115	ENOG4105CIY	formyltetrahydrofolate deformylase
GRF56_16125	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
GRF56_16140	ENOG4105E4C	Lytic transglycosylase catalytic
GRF56_16145	ENOG4105D8C	Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity)
GRF56_16155	ENOG4105CHM	Aminotransferase
GRF56_16160	ENOG4105CSX	c4-dicarboxylate anaerobic carrier
GRF56_16165	ENOG4105RKW	reductase (By
GRF56_16180	ENOG4105WWK	YheO domain protein
GRF56_16185	ENOG4105CEM	UPF0597 protein
GRF56_16190	ENOG4105KME	endoribonuclease L-psp
GRF56_16195	ENOG4105C44	Serine transporter
GRF56_16215	ENOG4105DP5	Catalyzes the biosynthesis of agmatine from arginine (By similarity)
GRF56_16220	ENOG4105D42	Cleaves the N-terminal amino acid of tripeptides (By similarity)
GRF56_16235	ENOG4105C3E	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine (By similarity)
GRF56_16245	ENOG4108YYC	ycei family
GRF56_16250	ENOG4105CC0	LysR family Transcriptional regulator
GRF56_16260	ENOG4105CKU	formyltetrahydrofolate synthetase
GRF56_16265	ENOG4105C8Q	Methyl-accepting chemotaxis
GRF56_16270	ENOG4105C8Q	Methyl-accepting chemotaxis
GRF56_16275	ENOG4105EUJ	GTP cyclohydrolase i
GRF56_16280	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
GRF56_16285	ENOG4105D06	uba thif-type nad fad binding protein
GRF56_16305	ENOG4105D3C	The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters (By similarity)
GRF56_16310	ENOG4105CGB	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system (By similarity)
GRF56_16315	ENOG4105E0C	molybdate abc transporter
GRF56_16320	ENOG4108S6J	ABC transporter, periplasmic molybdate-binding protein
GRF56_16325	ENOG4108ZAF	Molybdopterin
GRF56_16330	ENOG4105M00	molybdopterin converting factor, subunit 1
GRF56_16335	ENOG4108YXW	Together with MoaA, is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
GRF56_16340	ENOG4108RIR	Molybdenum cofactor biosynthesis protein
GRF56_16345	ENOG4105CUW	cytochrome C-TYPE protein
GRF56_16355	ENOG4105GXZ	Ferredoxin-type protein NapH
GRF56_16360	ENOG4108BGM	Quinol dehydrogenase periplasmic component
GRF56_16365	ENOG4107QIW	Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity)
GRF56_16380	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
GRF56_16385	ENOG4105BZU	Histidine kinase
GRF56_16390	ENOG4105WH1	Two component transcriptional regulator luxr family
GRF56_16405	ENOG4105BZU	Histidine kinase
GRF56_16415	ENOG4105CHW	UPF0052 protein
GRF56_16425	ENOG4105E7A	Glutamine amidotransferase
GRF56_16430	ENOG4105F55	Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate (By similarity)
GRF56_16435	ENOG4107QPN	acyl-Coa dehydrogenase
GRF56_16440	ENOG4105CH2	amidohydrolase
GRF56_16445	ENOG4105VDB	UPF0125 protein
GRF56_16450	ENOG4108Z1B	Cyclase dehydrase
GRF56_16455	ENOG4108UH4	Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity)
GRF56_16510	ENOG4105XB7	anti-repressor protein
GRF56_16675	ENOG4105NY2	NinB protein
GRF56_16750	ENOG41076J9	exonuclease VIII
GRF56_16780	ENOG4105DH7	May be involved in recombination (By similarity)
GRF56_16840	ENOG4108IYS	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
GRF56_16845	ENOG4105BZU	Histidine kinase
GRF56_16850	ENOG4105BZU	Histidine kinase
GRF56_16855	ENOG4108IEG	Formate dehydrogenase Alpha subunit
GRF56_16865	ENOG4107SSZ	Phosphatase
GRF56_16875	ENOG4107QPN	acyl-Coa dehydrogenase
GRF56_16880	ENOG4105BZS	acriflavin resistance protein
GRF56_16890	ENOG4105NHU	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group (By similarity)
GRF56_16925	ENOG41066XE	Type III export protein
GRF56_16955	ENOG4108KB1	transcriptional regulator, arac family
GRF56_16970	ENOG4106V6P	Exoenzyme S synthesis protein C
GRF56_17090	ENOG4105C87	Aminotransferase class I and II
GRF56_17095	ENOG4105CI1	PTS System
GRF56_17100	ENOG4107P2S	Transcriptional regulator
GRF56_17130	ENOG4105DM4	PTS System
GRF56_17135	ENOG4105CXY	transporter
GRF56_17140	ENOG4108YRF	PTS System
GRF56_17150	ENOG4108R99	pseudouridine synthase
GRF56_17160	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
GRF56_17165	ENOG41075W9	High frequency lysogenization protein HflD homolog
GRF56_17170	ENOG4107QTF	adenylosuccinate lyase
GRF56_17175	ENOG4105EZE	Cupin 4 family protein
GRF56_17195	ENOG4108RXX	maleylacetoacetate isomerase
GRF56_17200	ENOG4108S7T	Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) (By similarity)
GRF56_17240	ENOG4105M2J	Glutaredoxin
GRF56_17245	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
GRF56_17255	ENOG410903C	(LipO)protein
GRF56_17265	ENOG4105KWW	Biogenesis protein
GRF56_17270	ENOG4107QX9	Thiol disulfide interChange protein
GRF56_17275	ENOG4105DA4	cytochrome c-type biogenesis protein
GRF56_17280	ENOG4108ZKK	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH (By similarity)
GRF56_17285	ENOG4105X3C	heme exporter protein
GRF56_17290	ENOG41060IM	Heme exporter protein
GRF56_17295	ENOG4105CA5	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes (By similarity)
GRF56_17310	ENOG4108V3W	Chemotaxis protein, CheW
GRF56_17320	ENOG4107QJE	Chromosome Partitioning Protein
GRF56_17325	ENOG4108SEK	ompa motb domain protein
GRF56_17330	ENOG4105E14	MotA TolQ exbB proton channel
GRF56_17335	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
GRF56_17340	ENOG4105CBS	Chea signal transduction histidine kinase
GRF56_17345	ENOG4108KCC	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P) (By similarity)
GRF56_17350	ENOG4108VYJ	response regulator receiver protein
GRF56_17355	ENOG4105DN4	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
GRF56_17365	ENOG4105FZW	flagellar biosynthesis regulator FlhF
GRF56_17370	ENOG4105D7B	Flagellar biosynthesis protein flha
GRF56_17375	ENOG4105D00	flagellar biosynthetic protein flhB
GRF56_17380	ENOG4105D19	Role in flagellar biosynthesis (By similarity)
GRF56_17385	ENOG4105VS8	Flagellar biosynthetic protein fliq
GRF56_17390	ENOG4105CN7	Flagellar biosynthetic protein FliP
GRF56_17395	ENOG4105VTB	flagellar biosynthesis protein fliO
GRF56_17400	ENOG4105DD5	Flagellar motor switch protein
GRF56_17405	ENOG4105D24	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
GRF56_17425	ENOG4108JIR	Flagellum-specific ATP synthase
GRF56_17435	ENOG4105CS3	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
GRF56_17440	ENOG4105C1F	The M ring may be actively involved in energy transduction (By similarity)
GRF56_17445	ENOG4105VQ0	flagellar hook-basal body complex protein fliE
GRF56_17465	ENOG4105CA9	Pyruvate kinase
GRF56_17470	ENOG4106KNT	transcriptional regulator
GRF56_17475	ENOG4105CHC	glucokinase (EC 2.7.1.2)
GRF56_17500	ENOG4108NVR	Methyl-accepting chemotaxis
GRF56_17505	ENOG4106TNF	Periplasmic binding protein
GRF56_17510	ENOG4105C2W	permease
GRF56_17525	ENOG4107R1I	NAD-dependent malic enzyme
GRF56_17545	ENOG4105QAX	Iron-sulfur
GRF56_17550	ENOG4108IEG	Formate dehydrogenase Alpha subunit
GRF56_17550	ENOG4108IEG	Formate dehydrogenase Alpha subunit
GRF56_17590	ENOG4107H9G	Necessary for formate dehydrogenase activity (By similarity)
GRF56_17600	ENOG4105BZU	Histidine kinase
GRF56_17605	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
GRF56_17615	ENOG4107A5B	Binding-protein-dependent transport systems, inner membrane component
GRF56_17620	ENOG4108IUZ	ABC transporter
GRF56_17625	ENOG4105C6R	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor (By similarity)
GRF56_17630	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
GRF56_17635	ENOG4105DR8	Membrane
GRF56_17640	ENOG4108ESY	Metal dependent phosphohydrolase
GRF56_17650	ENOG4107SDU	Methyl-accepting chemotaxis
GRF56_17680	ENOG4105XIQ	Protein of unknown function (DUF2517)
GRF56_17700	ENOG4105BZU	Histidine kinase
GRF56_17715	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
GRF56_17725	ENOG4108JQ7	(ABC) transporter
GRF56_17735	ENOG4105RD7	BadF BadG BcrA BcrD
GRF56_17740	ENOG4105E2D	ec 3.2.1.52
GRF56_17745	ENOG4107RHT	methyl-accepting chemotaxis sensory transducer with Pas Pac sensor
GRF56_17755	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
GRF56_17760	ENOG4105EY2	Catalyzes the hydrolysis of N(2)-succinylarginine into N(2)-succinylornithine, ammonia and CO(2) (By similarity)
GRF56_17785	ENOG4105BZU	Histidine kinase
GRF56_17790	ENOG41068CG	regulatoR
GRF56_17815	ENOG4108NJZ	Sensory box GGDEF EAL domain protein
GRF56_17820	ENOG4105CFP	Peptidase U32
GRF56_17825	ENOG4105K5D	4fe-4S ferredoxin iroN-sulfur binding
GRF56_17835	ENOG41090EX	DsrE family
GRF56_17840	ENOG4105BZU	Histidine kinase
GRF56_17845	ENOG4105E5W	Transporter
GRF56_17850	ENOG4105ERU	peptidase
GRF56_17855	ENOG4105UBK	short-chain dehydrogenase reductase
GRF56_17860	ENOG4105C5Q	Transcriptional regulator
GRF56_17870	ENOG4105C87	Aminotransferase class I and II
GRF56_17885	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
GRF56_17890	ENOG4108V1U	phospholipid-binding protein
GRF56_17905	ENOG4105D5S	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine (By similarity)
GRF56_17915	ENOG4108VKA	Acts as a radical domain for damaged PFL and possibly other radical proteins (By similarity)
GRF56_17920	ENOG4105CK2	sodium dicarboxylate symporter
GRF56_17925	ENOG4105CXR	Phospho-2-dehydro-3-deoxyoctonate aldolase
GRF56_17930	ENOG41063JG	Transcriptional regulator
GRF56_17940	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
GRF56_17945	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
GRF56_17950	ENOG4105C7E	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) (By similarity)
GRF56_17955	ENOG4105C1U	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein (By similarity)
GRF56_17960	ENOG4105CTR	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol (By similarity)
GRF56_17970	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
GRF56_17975	ENOG4105CGH	5'-nucleotidase
GRF56_17980	ENOG4108ZPD	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity)
GRF56_17985	ENOG4105C3G	gtp-binding protein
GRF56_17995	ENOG4108NF7	phage-type endonuclease
GRF56_18025	ENOG4105F5W	AtP-binding protein
GRF56_18030	ENOG4105D70	Integrase catalytic subunit
GRF56_18050	ENOG4105W5Q	DNA repair protein (RadC
GRF56_18075	ENOG4107EV4	once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system (By similarity)
GRF56_18135	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
GRF56_18225	ENOG4107QWE	)-transporter
GRF56_18230	ENOG4106Z1T	Nicotinamide Mononucleotide Transporter
GRF56_18235	ENOG4108I5U	Uridine phosphorylase
GRF56_18255	ENOG4105CG3	alpha amylase, catalytic region
GRF56_18260	ENOG4105D95	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin (By similarity)
GRF56_18270	ENOG4107VXZ	Hydrolase
GRF56_18285	ENOG4105C26	Dehydrogenase
GRF56_18295	ENOG4105C8Y	Acetylornithine aminotransferase
GRF56_18300	ENOG4105DDQ	anthranilate synthase
GRF56_18310	ENOG4105C31	Tryptophanyl-tRNA synthetase
GRF56_18315	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
GRF56_18320	ENOG4105DJV	ribulose-phosphate 3-epimerase
GRF56_18325	ENOG4105DFE	Dna adenine methylase
GRF56_18335	ENOG4105D49	3-dehydroquinate synthase
GRF56_18340	ENOG4105KHV	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
GRF56_18345	ENOG4105E4G	Type IV pilus
GRF56_18370	ENOG4108JQC	penicillin-binding protein 1A
GRF56_18375	ENOG4105C5Q	Transcriptional regulator
GRF56_18380	ENOG4105C8Q	Methyl-accepting chemotaxis
GRF56_18395	ENOG4105EJC	lysr family transcriptional regulator
GRF56_18405	ENOG4105DR5	peptidase
GRF56_18415	ENOG4105EGS	Mechanosensitive ion channel
GRF56_18420	ENOG4108QXE	glycerophosphoryl diester phosphodiesterase
GRF56_18425	ENOG4105C8Q	Methyl-accepting chemotaxis
GRF56_18435	ENOG4105E33	succinate dehydrogenase
GRF56_18440	ENOG4108WJH	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane (By similarity)
GRF56_18445	ENOG4108VP9	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane (By similarity)
GRF56_18450	ENOG41074DU	domain protein
GRF56_18455	ENOG4108P2H	Inner membrane protein YjiG
GRF56_18460	ENOG4105D42	Cleaves the N-terminal amino acid of tripeptides (By similarity)
GRF56_18485	ENOG4108IQE	Amp-dependent synthetase and ligase
GRF56_18495	ENOG4105EMU	Dehydrogenase
GRF56_18505	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
GRF56_18510	ENOG4105DHQ	Histidine kinase
GRF56_18530	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
GRF56_18540	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
GRF56_18555	ENOG4105C5I	Dehydrogenase
GRF56_18590	ENOG4105BZU	Histidine kinase
GRF56_18595	ENOG4105VEQ	Cold shock protein
GRF56_18600	ENOG4106XMA	In vivo, quickly hydrolyzes the ureidoacrylate peracid to avoid toxicity, but can also hydrolyzes ureidoacrylate that is formed spontaneously from ureidoacrylate peracid. One of the products of hydrolysis, carbamate, hydrolyzes spontaneously, thereby releasing one of the pyrimidine rings nitrogen atoms as ammonia and one of its carbons as CO2 (By similarity)
GRF56_18605	ENOG4105EAK	ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family
GRF56_18610	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
GRF56_18615	ENOG4105C9A	Phoh family
GRF56_18620	ENOG4105KGE	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA (By similarity)
GRF56_18625	ENOG4108JU5	Magnesium and cobalt efflux protein
GRF56_18630	ENOG4105CE8	Transfers the fatty acyl group on membrane lipoproteins (By similarity)
GRF56_18635	ENOG4107SWG	transcriptional regulator MERR family
GRF56_18640	ENOG4105C2R	Single-stranded-DNA-specific exonuclease (RecJ)
GRF56_18650	ENOG4105M2E	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell (By similarity)
GRF56_18660	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
GRF56_18665	ENOG41071R3	Low-potential electron donor to a number of redox enzymes (By similarity)
GRF56_18670	ENOG4105D1U	peptidase U62 modulator of DNA gyrase
GRF56_18680	ENOG4107PAI	alpha helical protein
GRF56_18685	ENOG4105C8T	Leucyl-tRNA synthetase
GRF56_18700	ENOG4108Z1W	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity)
GRF56_18705	ENOG4105KEM	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation (By similarity)
GRF56_18710	ENOG4108UXA	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA (By similarity)
GRF56_18715	ENOG4105CJN	penicillin-binding protein
GRF56_18720	ENOG4105CNI	cell division protein FtsW
GRF56_18725	ENOG4105CVE	Lytic murein transglycosylase
GRF56_18730	ENOG4105K6T	rare lipoprotein A
GRF56_18735	ENOG4105DZ1	carboxypeptidase
GRF56_18740	ENOG4108Z43	UPF0250 protein
GRF56_18745	ENOG4108BDP	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity)
GRF56_18750	ENOG4105C0G	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity)
GRF56_18770	ENOG4105VUT	cytoplasmic protein
GRF56_18775	ENOG4105HDK	L-asparaginase
GRF56_18780	ENOG4105D6U	Sodium Glutamate Symporter
GRF56_18785	ENOG4105C8Q	Methyl-accepting chemotaxis
GRF56_18795	ENOG4105CRK	lysyL-tRNA synthetase
GRF56_18800	ENOG4107TIF	Phenazine biosynthesis protein, PhzF family
GRF56_18805	ENOG4107EER	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity)
GRF56_18810	ENOG4105ET1	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate (By similarity)
GRF56_18815	ENOG4105ET3	Reduction of activated sulfate into sulfite (By similarity)
GRF56_18825	ENOG4107XM3	UPF0442 protein
GRF56_18830	ENOG4105DWK	Membrane
GRF56_18840	ENOG4108RIR	Molybdenum cofactor biosynthesis protein
GRF56_18850	ENOG4105SUV	lipoprotein YgdR
GRF56_18855	ENOG4107RM6	sulfurtransferase
GRF56_18860	ENOG4105CSV	Glutaminase
GRF56_18865	ENOG41090ED	Protein with unknown function (DUF469)
GRF56_18870	ENOG4105CZ1	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity)
GRF56_18875	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
GRF56_18880	ENOG4105BZU	Histidine kinase
GRF56_18885	ENOG4105ECP	epimerase
GRF56_18890	ENOG4105CV6	ABC transporter, permease
GRF56_18895	ENOG4108I0Y	(ABC) transporter
GRF56_18900	ENOG4108UJV	acyl-CoA thioesterase i
GRF56_18905	ENOG4107R88	Chemotaxis protein (CheV)
GRF56_18950	ENOG4108M1A	Chitin-binding protein
GRF56_18955	ENOG4108MA4	Peptidase M66
GRF56_18975	ENOG4105BZU	Histidine kinase
GRF56_18985	ENOG4105VMP	Transcriptional regulator
GRF56_18995	ENOG4105D8G	Major Facilitator superfamily
GRF56_19020	ENOG4105PYN	Pyridoxamine 5-phosphate oxidase-related
GRF56_19025	ENOG41090JE	Utilization Protein
GRF56_19035	ENOG4105EHG	Permease protein
GRF56_19055	ENOG4108YXI	Secondary thiamine-phosphate synthase enzyme
GRF56_19060	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
GRF56_19065	ENOG4105CDU	Replicative dna helicase
GRF56_19075	ENOG4108YZY	peptidylprolyl cis-trans isomerase
GRF56_19080	ENOG4105VKU	nucleicacid-binding protein
GRF56_19090	ENOG4107R88	Chemotaxis protein (CheV)
GRF56_19095	ENOG4105DNZ	Alpha Beta Hydrolase
GRF56_19105	ENOG4105YP7	UPF0270 protein
GRF56_19110	ENOG4105CJE	phosphoribulokinase (EC 2.7.1.19)
GRF56_19125	ENOG4108UKZ	OsmC family
GRF56_19130	ENOG4107RYR	Transcriptional regulator, Crp Fnr family
GRF56_19165	ENOG4105DD7	kinase (PfkB family
GRF56_19170	ENOG4105D53	Catalyzes the hydrolysis of pseudouridine 5'-phosphate (PsiMP) to ribose 5-phosphate and uracil (By similarity)
GRF56_19195	ENOG4105KQT	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome (By similarity)
GRF56_19200	ENOG4105BZU	Histidine kinase
GRF56_19215	ENOG4105D0C	transport protein
GRF56_19220	ENOG4108UT2	hemolysin iii
GRF56_19225	ENOG4105DY8	decarboxylase
GRF56_19230	ENOG4107835	probably involved in intracellular septation (By similarity)
GRF56_19235	ENOG4105K9H	YciI-like protein
GRF56_19240	ENOG4108RNI	3'(2')5'-bisphosphate nucleotidase
GRF56_19245	ENOG4105CSZ	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate (By similarity)
GRF56_19250	ENOG41071DT	Involved in DNA repair and RecF pathway recombination (By similarity)
GRF56_19260	ENOG4108ZBM	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity)
GRF56_19265	ENOG4105C3F	Signal peptidase i
GRF56_19270	ENOG4105C4S	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity)
GRF56_19280	ENOG4105VQK	sigma E regulatory protein, MucB RseB
GRF56_19285	ENOG41069PW	sigma-e factor negative regulatory protein
GRF56_19290	ENOG4105EMN	RNA polymerase sigma factor
GRF56_19295	ENOG4108IYU	L-aspartate oxidase
GRF56_19305	ENOG4105Y75	tpr repeat protein
GRF56_19310	ENOG4106XY2	Folate-binding protein involved in regulating the level of ATP-DnaA and in the modification of some tRNAs. It is probably a key factor in regulatory networks that act via tRNA modification, such as initiation of chromosomal replication (By similarity)
GRF56_19335	ENOG4105CSG	Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps (By similarity)
GRF56_19350	ENOG4105CJP	fad dependent oxidoreductase
GRF56_19355	ENOG4105D2N	Aldolase
GRF56_19360	ENOG4105BZA	Phosphoglycerate kinase
GRF56_19365	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
GRF56_19370	ENOG4105DKQ	ROK family
GRF56_19375	ENOG4105CFZ	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III (By similarity)
GRF56_19380	ENOG4105E09	nadh pyrophosphatase
GRF56_19385	ENOG4105C26	Dehydrogenase
GRF56_19390	ENOG4106MWK	domain protein
GRF56_19395	ENOG4105EYW	Ion transport protein
GRF56_19400	ENOG4108NVR	Methyl-accepting chemotaxis
GRF56_19405	ENOG4105CE6	Adenylation and deadenylation of glutamate--ammonia ligase (By similarity)
GRF56_19445	ENOG4105E09	nadh pyrophosphatase
GRF56_19470	ENOG4107QWG	2-Nitropropane dioxygenase
GRF56_19485	ENOG4105CA0	peroxidase
GRF56_19490	ENOG4107V4F	S-adenosyl-l-methionine hydroxide adenosyltransferase
GRF56_19500	ENOG4105BZU	Histidine kinase
GRF56_19505	ENOG4105C1J	atp-dependent rna helicase
GRF56_19515	ENOG4107YH7	Beta-lactamase (EC 3.5.2.6)
GRF56_19530	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
GRF56_19535	ENOG4105DWY	Agmatine deiminase
GRF56_19550	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
GRF56_19560	ENOG4108K5P	(LipO)protein
GRF56_19565	ENOG4108UM1	dedA family
GRF56_19570	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
GRF56_19575	ENOG4105CV2	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates (By similarity)
GRF56_19580	ENOG4106NZV	Responsible for synthesis of pseudouridine from uracil- 13 in transfer RNAs (By similarity)
GRF56_19585	ENOG4108UH8	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (By similarity)
GRF56_19590	ENOG4105CE5	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) (By similarity)
GRF56_19595	ENOG4105XX3	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity)
GRF56_19600	ENOG4105CK7	Sodium proline symporter
GRF56_19610	ENOG4107N1Q	ErfK YbiS YcfS YnhG family protein
GRF56_19615	ENOG4105CUY	Mechanosensitive ion channel
GRF56_19625	ENOG4105XEP	YhcH YjgK YiaL family protein
GRF56_19650	ENOG4107SQD	Transcriptional regulator, GntR family
GRF56_19670	ENOG4105C5H	ABC transporter
GRF56_19680	ENOG4105D6S	protein involved in catabolism of external DNA
GRF56_19725	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
GRF56_19730	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
GRF56_19735	ENOG4105DXN	mazG family
GRF56_19740	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
GRF56_19745	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
GRF56_19750	ENOG4105BZU	Histidine kinase
GRF56_19755	ENOG4108W15	Protein of unknown function (DUF1456)
GRF56_19760	ENOG4108VBV	N-Acetylmuramoyl-L-alanine amidase
GRF56_19765	ENOG4108RMU	ferritin dps family protein
GRF56_19770	ENOG4105EJ7	Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O (By similarity)
GRF56_19780	ENOG4105CMR	udp-glucose 4-epimerase
GRF56_19785	ENOG41076MN	Phosphoesterase, PA-phosphatase related
GRF56_19790	ENOG4105DFU	Cell wall formation (By similarity)
GRF56_19795	ENOG4108UMA	3-octaprenyl-4-hydroxybenzoate carboxy-lyase
GRF56_19800	ENOG410630P	Transcriptional regulator
GRF56_19805	ENOG4108UGV	hypoxanthine phosphoribosyltransferase
GRF56_19810	ENOG4105DA5	(ABC) transporter
GRF56_19815	ENOG4105E3A	(ABC) transporter
GRF56_19820	ENOG4105DCU	2-hydroxyglutaryl-CoA dehydratase
GRF56_19825	ENOG4105CIZ	coA-substrate-specific enzyme activase
GRF56_19845	ENOG4108ETY	sodium dicarboxylate symporter
GRF56_19855	ENOG4108IAA	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate (By similarity)
GRF56_19860	ENOG4105CCG	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is tranferred onto alpha-ketoisovalerate to form ketopantoate (By similarity)
GRF56_19865	ENOG4105K8U	2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
GRF56_19870	ENOG4105DJ0	Poly(A) Polymerase
GRF56_19875	ENOG4106F3G	Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon (By similarity)
GRF56_19880	ENOG4108V7X	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
GRF56_19885	ENOG4105PW4	Sugar fermentation stimulation protein homolog
GRF56_19895	ENOG4105CQ7	ATP-dependent helicase
GRF56_19900	ENOG4105BZ4	penicillin-binding protein
GRF56_19905	ENOG4108YZK	glyoxalase bleomycin resistance protein dioxygenase
GRF56_19910	ENOG4108ZBZ	Catalyzes the excretion of spermidine (By similarity)
GRF56_19915	ENOG41090TI	Catalyzes the excretion of spermidine (By similarity)
GRF56_19925	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
GRF56_19930	ENOG4105F0N	pyrophosphate phospho-hydrolase
GRF56_19945	ENOG4108UUE	Transcriptional regulator
GRF56_19980	ENOG4107RHT	methyl-accepting chemotaxis sensory transducer with Pas Pac sensor
GRF56_20005	ENOG4108I67	Catalyzes the synthesis of activated sulfate (By similarity)
GRF56_20015	ENOG4105C3T	may be the GTPase, regulating ATP sulfurylase activity (By similarity)
GRF56_20020	ENOG4105C11	sulfate adenylyltransferase), subunit 2
GRF56_20025	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
GRF56_20030	ENOG4107QX8	SPFH domain, Band 7 family protein
GRF56_20035	ENOG4105G5H	Membrane
GRF56_20040	ENOG4105C8Q	Methyl-accepting chemotaxis
GRF56_20045	ENOG4105D0I	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate (By similarity)
GRF56_20050	ENOG4105DSB	aldose 1-epimerase
GRF56_20060	ENOG4107RTM	4-alpha-glucanotransferase (EC 2.4.1.25)
GRF56_20065	ENOG4105C9C	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity)
GRF56_20075	ENOG4105E0X	reductase
GRF56_20100	ENOG4105EW9	transcriptional regulator AsnC family
GRF56_20115	ENOG4108K4B	hydrolase
GRF56_20130	ENOG4105C8J	)-transporter
GRF56_20140	ENOG4105C8J	)-transporter
GRF56_20205	ENOG4105UFD	tol-pal system protein YbgF
GRF56_20210	ENOG4105KCK	Peptidoglycan-associated lipoprotein
GRF56_20215	ENOG4107R6Y	Involved in the TonB-independent uptake of proteins (By similarity)
GRF56_20225	ENOG4105M8F	Biopolymer transport protein exbD tolR
GRF56_20230	ENOG4105E02	MotA TolQ exbB proton channel
GRF56_20235	ENOG4107YD3	Thioesterase
GRF56_20240	ENOG4105KJB	cyd operon protein YbgE
GRF56_20250	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
GRF56_20255	ENOG4105C4M	(Ubiquinol oxidase) subunit I
GRF56_20260	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
GRF56_20265	ENOG4105KA4	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity)
GRF56_20270	ENOG4105C8Q	Methyl-accepting chemotaxis
GRF56_20275	ENOG4108ZUB	Lysine exporter protein (Lyse ygga)
GRF56_20280	ENOG4105VJY	transcriptional regulator
GRF56_20285	ENOG4105NNS	Autoinducer synthesis protein
GRF56_20290	ENOG4105CXD	Specific inhibitor of chromosomal initiation of replication in vitro. Binds the three 13-mers in the origin (oriC) to block initiation of replication (By similarity)
GRF56_20295	ENOG4108IEC	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction (By similarity)
GRF56_20310	ENOG4107VXZ	Hydrolase
GRF56_20315	ENOG4105KW8	RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity)
GRF56_20320	ENOG4105F1S	paraquat-inducible protein a
GRF56_20325	ENOG4105DY2	Paraquat-inducible protein b
GRF56_20335	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
GRF56_20340	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
GRF56_20345	ENOG4108RZ4	Short-chain dehydrogenase reductase Sdr
GRF56_20360	ENOG4105E39	Enoyl-CoA hydratase
GRF56_20365	ENOG4106WH9	Protein of unknown function (DUF2753)
GRF56_20370	ENOG4105EQK	-acetyltransferase
GRF56_20380	ENOG4107QSI	ABC, transporter
GRF56_20390	ENOG4107RHT	methyl-accepting chemotaxis sensory transducer with Pas Pac sensor
GRF56_20395	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
GRF56_20400	ENOG4105MYN	Zinc uptake regulation protein
GRF56_20415	ENOG4105CWM	branched-chain amino acid transport system II carrier protein
GRF56_20420	ENOG4105CWM	branched-chain amino acid transport system II carrier protein
GRF56_20425	ENOG4107S47	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC) (By similarity)
GRF56_20430	ENOG4105C1J	atp-dependent rna helicase
GRF56_20435	ENOG4107YB6	acetyltransferase, (GNAT) family
GRF56_20445	ENOG4105C2N	RNA methyltransferase TrmH family group 3
GRF56_20450	ENOG4105C40	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity)
GRF56_20455	ENOG4106TD9	Diguanylate cyclase
GRF56_20460	ENOG4105UYK	outer membrane protein a
GRF56_20470	ENOG4105H4F	exported protein
GRF56_20480	ENOG4105KMG	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes (By similarity)
GRF56_20485	ENOG4105CEN	a g-specific adenine glycosylase
GRF56_20490	ENOG4105D4J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
GRF56_20510	ENOG4105R2J	Conserved Protein
GRF56_20520	ENOG4105DR5	peptidase
GRF56_20540	ENOG4105NXV	High-affinity zinc uptake system protein
GRF56_20545	ENOG4105FDK	ABC transporter
GRF56_20550	ENOG4105FAV	ABC, transporter
GRF56_20555	ENOG4105ETT	transcriptional Regulator, LysR family
GRF56_20560	ENOG4105DFI	Membrane
GRF56_20565	ENOG4108RG0	uracil-dna glycosylase
GRF56_20580	ENOG41082IR	Excinuclease ABC C subunit domain protein
GRF56_20595	ENOG41087YS	Phage shock protein A
GRF56_20600	ENOG4107S7E	1-acyl-sn-glycerol-3-phosphate acyltransferase
GRF56_20620	ENOG4105N2G	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
GRF56_20630	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
GRF56_20635	ENOG4107EXU	Short-chain dehydrogenase reductase Sdr
GRF56_20640	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
GRF56_20660	ENOG4105DUX	Transporter
GRF56_20670	ENOG4105CBN	LysR family transcriptional regulator
GRF56_20680	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
GRF56_20685	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
GRF56_20690	ENOG4105IPS	esterase
GRF56_20695	ENOG41070EG	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes (By similarity)
GRF56_20700	ENOG4108SX3	cytoplasmic protein
GRF56_20705	ENOG41087AY	ADP-Ribose pyrophosphatase
GRF56_20710	ENOG4105DFG	type I secretion outer membrane protein
GRF56_20715	ENOG4105DW0	Catalyzes the ADP transfer to D-glycero-D-manno-heptose 1-phosphate, yielding ADP-D,D-heptose (By similarity)
GRF56_20720	ENOG4105D1S	lipid A biosynthesis
GRF56_20725	ENOG4105CTS	PTS system mannitol-specific
GRF56_20730	ENOG4107SQ3	mannitol-1-phosphate 5-dehydrogenase
GRF56_20735	ENOG4105E61	Mannitol repressor protein
GRF56_20765	ENOG4108UPT	UPF0178 protein
GRF56_20770	ENOG4107K5X	Membrane-bound metal-dependent hydrolase
GRF56_20780	ENOG4105D9N	nucleoside
GRF56_20785	ENOG4105C1J	atp-dependent rna helicase
GRF56_20805	ENOG4105EIS	1,4-dihydroxy-2-naphthoate octaprenyltransferase
GRF56_20810	ENOG4105E4F	Isochorismate synthase
GRF56_20815	ENOG4105C4A	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC) (By similarity)
GRF56_20820	ENOG4107J5P	Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC). Is also able to catalyze the hydrolysis of the thioester bond in palmitoyl-CoA in vitro (By similarity)
GRF56_20825	ENOG4108IPT	Naphthoate synthase
GRF56_20830	ENOG4105DNI	Converts SHCHC to OSB (By similarity)
GRF56_20835	ENOG4105CEY	Amp-dependent synthetase and ligase
GRF56_20850	ENOG4105NEV	Fimbrial
GRF56_20855	ENOG4108FZ9	Chaperone
GRF56_20860	ENOG4106PG1	outer membrane usher protein
GRF56_20870	ENOG4105HMV	Fimbrial protein
GRF56_20880	ENOG4107MM9	BNR Asp-box repeat-containing protein
GRF56_20885	ENOG4107GZ4	SanA protein
GRF56_20900	ENOG4107R88	Chemotaxis protein (CheV)
GRF56_20905	ENOG410904N	short-chain dehydrogenase reductase
GRF56_20910	ENOG4105E0I	Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of tRNA(Met), by using acetyl-CoA as an acetyl donor and ATP (or GTP) (By similarity)
GRF56_20925	ENOG4108UQY	Iron-storage protein
GRF56_20930	ENOG4108Z5K	methylglyoxal synthase
GRF56_20935	ENOG4108I6A	alcohol dehydrogenase
GRF56_20945	ENOG4105DZW	Dipeptidase
GRF56_20950	ENOG4105EMU	Dehydrogenase
GRF56_20990	ENOG4105E0M	Sulfatase
GRF56_20995	ENOG4108YXU	transcriptional regulator AsnC family
GRF56_21005	ENOG4105CVG	Homoserine O-transsuccinylase
GRF56_21010	ENOG4105E4Y	Endoribonuclease that initiates mRNA decay (By similarity)
GRF56_21015	ENOG4108I62	cina-like protein
GRF56_21025	ENOG410667J	hydrolase
GRF56_21035	ENOG41090HJ	UPF0265 protein
GRF56_21075	ENOG4108JCI	Transcriptional regulator
GRF56_21080	ENOG4105DKK	Benzoate
GRF56_21090	ENOG4105SYT	Methylenetetrahydrofolate reductase
GRF56_21105	ENOG4105C8Q	Methyl-accepting chemotaxis
GRF56_21110	ENOG4105EIF	outer membrane protein W
GRF56_21115	ENOG4105BZU	Histidine kinase
GRF56_21120	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
GRF56_21140	ENOG4105P8Q	Curli production assembly transport component CsgG
GRF56_21150	ENOG4108XDW	curli assembly protein CsgE
GRF56_21155	ENOG41086KC	Transcriptional regulator
GRF56_21160	ENOG4108UUM	single-stranded DNA-binding protein
GRF56_21185	ENOG4105VEQ	Cold shock protein
GRF56_21190	ENOG4105C7N	Xanthine uracil vitamin C permease
GRF56_21195	ENOG4105CMT	Dihydroxyacetone kinase
GRF56_21200	ENOG4108UTZ	Dihydroxyacetone kinase
GRF56_21205	ENOG4105VDH	Dihydroxyacetone kinase
GRF56_21215	ENOG4108JU9	GAF modulated sigma54 specific transcriptional regulator Fis family
GRF56_21235	ENOG4105IPI	Membrane
GRF56_21250	ENOG4105VEJ	Heat shock protein
GRF56_21255	ENOG4105F4C	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress (By similarity)
GRF56_21260	ENOG4105DJ1	Phosphoenolpyruvate Carboxylase
GRF56_21275	ENOG4105VXR	cytoplasmic protein
GRF56_21280	ENOG4108R6G	acetyltransferase
GRF56_21285	ENOG4108XTF	Outer Membrane Lipoprotein
GRF56_21290	ENOG4105BZU	Histidine kinase
GRF56_21295	ENOG4106TD9	Diguanylate cyclase
GRF56_21305	ENOG4108TPP	exopolysaccharide synthesis
GRF56_21315	ENOG4105DWD	nucleoside recognition domain protein
GRF56_21340	ENOG4105K7Z	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP (By similarity)
GRF56_21345	ENOG4107ZVW	dihydroneopterin aldolase
GRF56_21350	ENOG4105K8U	2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
GRF56_21360	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
GRF56_21370	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
GRF56_21375	ENOG4108IJF	Heavy metal efflux pump, CzcA
GRF56_21380	ENOG4105CKI	cobalamin synthesis protein
GRF56_21390	ENOG4105BZU	Histidine kinase
GRF56_21395	ENOG4107QIJ	Aconitate hydratase 2
GRF56_21400	ENOG4105D78	K07001 NTE family protein
GRF56_21405	ENOG4108N3W	hemolysin secretion protein
GRF56_21410	ENOG4105BZU	Histidine kinase
GRF56_21415	ENOG4107QN2	dihydrolipoyl dehydrogenase
GRF56_21420	ENOG4107QSN	dihydrolipoamide acetyltransferase
GRF56_21425	ENOG4105DAQ	Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) (By similarity)
GRF56_21430	ENOG41073TP	transcriptional regulator
GRF56_21445	ENOG4105D18	nicotinate-nucleotide pyrophosphorylase
GRF56_21455	ENOG4107QHF	type ii secretion system protein e
GRF56_21460	ENOG4105D7Q	type ii secretion system
GRF56_21475	ENOG4105DHA	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity (By similarity)
GRF56_21480	ENOG41067SF	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase (By similarity)
GRF56_21485	ENOG4105EJF	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity)
GRF56_21490	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
GRF56_21500	ENOG4105C7C	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
GRF56_21505	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
GRF56_21510	ENOG4105CIT	This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity)
GRF56_21515	ENOG4105K7E	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly (By similarity)
GRF56_21520	ENOG4105DFU	Cell wall formation (By similarity)
GRF56_21525	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
GRF56_21530	ENOG4105CNI	cell division protein FtsW
GRF56_21535	ENOG4105DMZ	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity)
GRF56_21540	ENOG4105CPY	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity)
GRF56_21545	ENOG4108EQQ	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein (By similarity)
GRF56_21550	ENOG4107EEN	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity)
GRF56_21555	ENOG4105CJN	penicillin-binding protein
GRF56_21560	ENOG41063Y6	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity)
GRF56_21565	ENOG4105CGJ	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity)
GRF56_21570	ENOG4108V6E	Cell division protein mraZ
GRF56_21580	ENOG4105E9H	Lytic Murein transglycosylase
GRF56_21595	ENOG4107RD7	Flagellar Motor Protein, MotA
GRF56_21620	ENOG4105MQ3	flagellar protein FliS
GRF56_21625	ENOG410804A	Flagellar hook-associated 2 domain-containing protein
GRF56_21630	ENOG4105I03	Flagellin
GRF56_21640	ENOG4105DTJ	flagellar hook-associated protein
GRF56_21645	ENOG4105E1Q	flagellar hook-associated protein
GRF56_21655	ENOG4105D92	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity)
GRF56_21660	ENOG4107W7W	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity)
GRF56_21665	ENOG4105CGA	flagellar basal-body rod protein FlgG
GRF56_21670	ENOG4108KPB	Flagellar basal-body rod protein FlgF
GRF56_21675	ENOG4105BZE	flagellar hook protein, FlgE
GRF56_21680	ENOG4105W00	Flagellar hook capping protein
GRF56_21685	ENOG4108ZC9	flagellar basal-body rod protein flgc
GRF56_21690	ENOG4105K88	Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body (By similarity)
GRF56_21695	ENOG4105XZC	flagellar basal body P-ring biosynthesis protein FlgA
GRF56_21715	ENOG4108JIR	Flagellum-specific ATP synthase
GRF56_21725	ENOG4105CS3	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
GRF56_21730	ENOG4105C1F	The M ring may be actively involved in energy transduction (By similarity)
GRF56_21735	ENOG4105VQ0	flagellar hook-basal body complex protein fliE
GRF56_21740	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
GRF56_21750	ENOG4105D00	flagellar biosynthetic protein flhB
GRF56_21755	ENOG4105D19	Role in flagellar biosynthesis (By similarity)
GRF56_21760	ENOG4105VS8	Flagellar biosynthetic protein fliq
GRF56_21765	ENOG4105CN7	Flagellar biosynthetic protein FliP
GRF56_21770	ENOG4105DD5	Flagellar motor switch protein
GRF56_21785	ENOG4105CU0	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity)
GRF56_21790	ENOG4105E1C	Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1A (PBP1a) (By similarity)
GRF56_21795	ENOG41082RQ	UPF0102 protein
GRF56_21800	ENOG4105F55	Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate (By similarity)
GRF56_21805	ENOG4105W4M	Transport-associated protein
GRF56_21810	ENOG4105KB2	stringent starvation protein b
GRF56_21815	ENOG4107MKT	Stringent starvation protein a
GRF56_21820	ENOG4105EIX	cytochrome c1
GRF56_21825	ENOG4105DJ5	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
GRF56_21830	ENOG4108R5F	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
GRF56_21835	ENOG4108UJD	30S ribosomal protein S9
GRF56_21840	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
GRF56_21845	ENOG4105D6Z	AFG1 family ATPase
GRF56_21855	ENOG4105C0H	protease
GRF56_21860	ENOG4105C0H	protease
GRF56_21890	ENOG41069H0	dihydroorotase EC 3.5.2.3
GRF56_21910	ENOG41080Z8	PHOSPHOCARRIER protein
GRF56_21915	ENOG4105C21	Displays ATPase and GTPase activities (By similarity)
GRF56_21920	ENOG4107RM2	PTS IIA-like nitrogen-regulatory protein PtsN
GRF56_21925	ENOG41080QH	sigma 54 modulation protein ribosomal protein S30EA
GRF56_21930	ENOG4105DTW	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
GRF56_21935	ENOG4108IUZ	ABC transporter
GRF56_21940	ENOG4105WI0	lipopolysaccharide transport periplasmic protein lptA
GRF56_21945	ENOG4108P1K	Required for the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane (By similarity)
GRF56_21950	ENOG4108Z4R	3-deoxy-d-manno-octulosonate 8-phosphate phosphatase
GRF56_21955	ENOG4105C2X	Arabinose 5-phosphate isomerase
GRF56_21960	ENOG4105DHJ	ABC, transporter
GRF56_21965	ENOG4105CY3	ABC transporter, permease
GRF56_21970	ENOG4107PE3	Mammalian cell entry related domain protein
GRF56_21975	ENOG4105E3I	toluene tolerance
GRF56_21985	ENOG4105VFK	BolA family
GRF56_21990	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
GRF56_21995	ENOG4105CMS	peptidase U62, modulator of DNA gyrase
GRF56_22000	ENOG4105N42	UPF0307 protein
GRF56_22005	ENOG4108Z86	Glutamine amidotransferase
GRF56_22015	ENOG4107RYR	Transcriptional regulator, Crp Fnr family
GRF56_22025	ENOG4105DFC	had-superfamily hydrolase, subfamily ia, variant
GRF56_22030	ENOG4108IYS	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
GRF56_22040	ENOG4105E4Z	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan (By similarity)
GRF56_22045	ENOG4105CU5	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity)
GRF56_22055	ENOG4105XQ6	frataxin-like protein
GRF56_22060	ENOG4106CJB	Phospholipase Carboxylesterase
GRF56_22065	ENOG4107T0K	Adenylate cyclase
GRF56_22070	ENOG4105D6W	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity)
GRF56_22075	ENOG41076E6	Uroporphyrinogen-III Synthase
GRF56_22080	ENOG4105ECF	c-methyltransferase
GRF56_22095	ENOG4105CBT	Fructose-1,6-bisphosphatase
GRF56_22115	ENOG4107SC7	Inner membrane transporter yjeM
GRF56_22120	ENOG41061WM	D-Alanyl-D-Alanine
GRF56_22140	ENOG4108IYS	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
GRF56_22155	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
GRF56_22220	ENOG4105VZ1	Replication Protein
GRF56_22230	ENOG4105ED4	portal protein